<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0056792-RA transcript Note:&quot;Similar to MAPK10 Mitogen-activated protein kinase 10 (Homo sapiens)&quot; offset:187 AED:0.44 eAED:0.49 QI:187|0.81|0.83|1|0.36|0.66|12|0|406</BlastOutput_query-def>
  <BlastOutput_query-len>1408</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056792-RA transcript Note:&quot;Similar to MAPK10 Mitogen-activated protein kinase 10 (Homo sapiens)&quot; offset:187 AED:0.44 eAED:0.49 QI:187|0.81|0.83|1|0.36|0.66|12|0|406</Iteration_query-def>
  <Iteration_query-len>1408</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>216.468</Hsp_bit-score>
      <Hsp_score>550</Hsp_score>
      <Hsp_evalue>6.85631e-66</Hsp_evalue>
      <Hsp_query-from>77</Hsp_query-from>
      <Hsp_query-to>1054</Hsp_query-to>
      <Hsp_hit-from>6</Hsp_hit-from>
      <Hsp_hit-to>345</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>127</Hsp_identity>
      <Hsp_positive>192</Hsp_positive>
      <Hsp_gaps>76</Hsp_gaps>
      <Hsp_align-len>371</Hsp_align-len>
      <Hsp_qseq>QFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVC*WITMAALWRDPASSSSQLGCIDCAAYDIMQNRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQME-LDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQLGT---------------------------PMAEFMKKLQPTVRNYVEN----RPK-------YAGYSFEKLFPDPPPKI-----YDKQLDEREHSIDEWKELIYKEVLDWEE</Hsp_qseq>
      <Hsp_hseq>EFIRTQIFGTVFEITNRYNDLNPVGMGAFGLVC------------------------SATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIF-----LSPLEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ--MTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENTLKFVTSLPHRDPIPFSERFKTVEPDAVDLLEKMLVFDPKKRITAADALAHPYSAPYHDPTDEPVADAKFDWHFNDADLPVDTWRVMMYSEILDFHK</Hsp_hseq>
      <Hsp_midline>+F   ++  + F +  RY +L P+G GA G+VC                        +A D + ++ VAIKK+ +PF     AKR YREL L+K + H+N+ICL ++F     L   +D+Y V EL   +L +++Q   L+ + + Y +YQ+L G+K++HSAG+IHRDLKPSNI++  +C LKI DFGLAR       MT YV TRYYRAPE++L    Y   VDIWS GCI  EMI G  LFPG DH+ Q++ I + LG+                           P +E  K ++P   + +E      PK          + +   + DP  +      +D   ++ +  +D W+ ++Y E+LD+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>199.519</Hsp_bit-score>
      <Hsp_score>506</Hsp_score>
      <Hsp_evalue>7.74587e-59</Hsp_evalue>
      <Hsp_query-from>83</Hsp_query-from>
      <Hsp_query-to>1045</Hsp_query-to>
      <Hsp_hit-from>8</Hsp_hit-from>
      <Hsp_hit-to>314</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>122</Hsp_identity>
      <Hsp_positive>187</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>334</Hsp_align-len>
      <Hsp_qseq>YSVEVGDSTFTVLKRYQNLKPIGSGAQGIVC*WITMAALWRDPASSSSQLGCIDCAAYDIMQNRNVAIKKLSRPFQNQTHAKRAYRELVLMKCV-NHKNIICLFN---VFTPQKSLEEFQDVYLVMELMDANLCQVIQ--MELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-----TAGNSFMMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQLGTPMAEFMKKL-QPTVRNYVENRPKYAGYSFEKLFPDPPPKIYDKQLDEREHSIDEWKELIYKEVLD</Hsp_qseq>
      <Hsp_hseq>HTFKVFNQDFSVDKRFQLIKEIGHGAYGIVC-----SARFAEAAEDTT-----------------VAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSI---NGLYLYEELMECDMHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALD--LLEQMLAFDPQKRITVDEALE</Hsp_hseq>
      <Hsp_midline>++ +V +  F+V KR+Q +K IG GA GIVC     +A + + A  ++                 VAIKK++  F      KR+ REL L++    HKNI CL++   VF P  S+     +YL  ELM+ ++ Q+I+    L         YQ+LCG+K++HSA ++HRDLKP N++V +DC LKI DFGLAR        NS  +T YV TR+YRAPE++L   GYT+ +D+WS GCI+ E + G  +F G D+++Q N+I++ LGTP  E ++++    V++Y+          F  L+P+   +  D  L E+  + D  K +   E L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>183.726</Hsp_bit-score>
      <Hsp_score>465</Hsp_score>
      <Hsp_evalue>3.21799e-54</Hsp_evalue>
      <Hsp_query-from>146</Hsp_query-from>
      <Hsp_query-to>1045</Hsp_query-to>
      <Hsp_hit-from>19</Hsp_hit-from>
      <Hsp_hit-to>305</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>116</Hsp_identity>
      <Hsp_positive>164</Hsp_positive>
      <Hsp_gaps>43</Hsp_gaps>
      <Hsp_align-len>315</Hsp_align-len>
      <Hsp_qseq>IGSGAQGIVC*WITMAALWRDPASSSSQLGCIDCAAYDIMQNRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQME-LDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLART-----------AGNSFMMTPYVVTRYYRAPEVIL-GMGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQLGTPMAEFMKKL--QPTVRNYVENRPKYAGYSFEKLFPDPPPKIYDKQLDEREHSIDEWKELIYKEVLD</Hsp_qseq>
      <Hsp_hseq>LGEGAYGVVC------------SATHKPTGEI------------VAIKKIE-PFDKPLFALRTLREIKILKHFKHENIITIFNIQRPD-SFENFNEVYIIQELMQTDLHRVISTQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHSDNDLRCIESPRAREYIKSLPMYPAAPLEKMFPRVNPKGID--LLQRMLVFDPAKRITAKEALE</Hsp_hseq>
      <Hsp_midline>+G GA G+VC            +++    G I            VAIKK+  PF     A R  RE+ ++K   H+NII +FN+  P  S E F +VY++ ELM  +L +VI  + L  + + Y IYQ L  +K LH + +IHRDLKPSN+++ S+C LK+ DFGLAR             G    MT YV TR+YRAPEV+L    Y+  +D+WS GCI+ E+     +FPG D+  Q   I   +GTP ++   +    P  R Y+++ P Y     EK+FP   PK  D  L +R    D  K +  KE L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>169.088</Hsp_bit-score>
      <Hsp_score>427</Hsp_score>
      <Hsp_evalue>1.50775e-48</Hsp_evalue>
      <Hsp_query-from>107</Hsp_query-from>
      <Hsp_query-to>949</Hsp_query-to>
      <Hsp_hit-from>6</Hsp_hit-from>
      <Hsp_hit-to>277</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>107</Hsp_identity>
      <Hsp_positive>158</Hsp_positive>
      <Hsp_gaps>43</Hsp_gaps>
      <Hsp_align-len>298</Hsp_align-len>
      <Hsp_qseq>TFTVLKRYQNLKPIGSGAQGIVC*WITMAALWRDPASSSSQLGCIDCAAYDIMQNRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVN-HKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQME------LDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSF--------MMTPYVVTRYYRAPEVILGMG-YTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQLGTPMAEFMKKLQPT-VRNYVENRPKYAGYSFEKLF</Hsp_qseq>
      <Hsp_hseq>TFDIPSQYKLVDLIGEGAYGTVC------------------------SAIHKPSGIKVAIKKI-QPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPV-SIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIANLPMRPPLPWETVW</Hsp_hseq>
      <Hsp_midline>TF +  +Y+ +  IG GA G VC                        +A        VAIKK+ +PF  +    R  RE+ L++  + H+NII + +   P  S+++   VYLV ELM+ +L +VI  +      L  + + Y  YQ+L  +K +HSA +IHRD+KPSN+++ S+C LK+ DFGLAR   +S          MT YV TR+YRAPE++L    YT  +DIWS GCI+ EM+ G  LFPG D+  Q   I+E LGTP  E   +++    + Y+ N P      +E ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>163.31</Hsp_bit-score>
      <Hsp_score>412</Hsp_score>
      <Hsp_evalue>6.94942e-46</Hsp_evalue>
      <Hsp_query-from>266</Hsp_query-from>
      <Hsp_query-to>967</Hsp_query-to>
      <Hsp_hit-from>47</Hsp_hit-from>
      <Hsp_hit-to>290</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>94</Hsp_identity>
      <Hsp_positive>144</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>247</Hsp_align-len>
      <Hsp_qseq>QNRNVAIKKLSRPFQNQTHAKRAYRELVLMKCV-NHKNIICLFN---VFTPQKSLEEFQDVYLVMELMDANLCQVIQME--LDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAG-----NSFMMTPYVVTRYYRAPEVILGMGY-TENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQLGTPMAEFMKKLQP-TVRNYVENRPKYAGYSFEKLFPDPPPK</Hsp_qseq>
      <Hsp_hseq>EETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGAL---NGVYLYEELMECDLSQIIRSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIPGRSFESILPGANPE</Hsp_hseq>
      <Hsp_midline>+  +VAI+K+   F N+   KR  REL L++ +  H NI+ LF+   VF P  +L     VYL  ELM+ +L Q+I+ E  L+       IYQ+LC +K++HSA ++H DLKP N++V SDC LKI +FGL+ +       N   +  Y+ + +Y+APE++L     T+ VDIWS GCI+ E++    +F G D++D  N I++ LGTP  E ++++    V NY+       G SFE + P   P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>156.762</Hsp_bit-score>
      <Hsp_score>395</Hsp_score>
      <Hsp_evalue>8.49469e-44</Hsp_evalue>
      <Hsp_query-from>128</Hsp_query-from>
      <Hsp_query-to>952</Hsp_query-to>
      <Hsp_hit-from>38</Hsp_hit-from>
      <Hsp_hit-to>304</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>103</Hsp_identity>
      <Hsp_positive>153</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>292</Hsp_align-len>
      <Hsp_qseq>YQNLKPIGSGAQGIVC*WITMAALWRDPASSSSQLGCIDCAAYDIMQNRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVN-HKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQ--MELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFM---------MTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQLGTPMAEFMKKLQPTVRNY----VENRPKYAGYSFEKLFP</Hsp_qseq>
      <Hsp_hseq>YEIIQFLGKGAYGTVC---SVKFKGRSPAA-------------------RIAVKKISNIFNKEILLKRAIRELKFMNFFKGHKNIVNLIDLEIVTSS--PYDGLYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDKDILIKFG-TIKAWNLGKNSNNPVYKKIPWSNIFP</Hsp_hseq>
      <Hsp_midline>Y+ ++ +G GA G VC   ++    R PA+                    +A+KK+S  F  +   KRA REL  M     HKNI+ L ++     S   +  +Y   EL+D +L +VI   ++L    + Y +YQ+LCG+K++HSA +IHRDLKP NI+   +  LKI DFGLAR     F          +T YV TR+YRAPE++L    Y+++VDIW+VGCI+ E      +F G D + Q  +II+ LGTP  + + K   T++ +      N P Y    +  +FP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>131.724</Hsp_bit-score>
      <Hsp_score>330</Hsp_score>
      <Hsp_evalue>8.86587e-35</Hsp_evalue>
      <Hsp_query-from>269</Hsp_query-from>
      <Hsp_query-to>991</Hsp_query-to>
      <Hsp_hit-from>62</Hsp_hit-from>
      <Hsp_hit-to>294</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>88</Hsp_identity>
      <Hsp_positive>141</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>253</Hsp_align-len>
      <Hsp_qseq>NRNVAIKKL--SRPFQNQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMELDHER-------MSYLIYQMLCGIKHLHS-AGIIHRDLKPSNIVVKSDC-TLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQLGTPMAEFMKKLQPTVRNYVENRPKYAGYSFEKLFPDPPPKIYDKQLDE</Hsp_qseq>
      <Hsp_hseq>NEKVAIKKVLQDKRFKN--------RELEIMKMLSHINIIDLKYFFYERDSQDEIY-LNLILEYMPQSLYQRLR-HFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILGTPSKQEICSMNP---NYMEHK-------FPQIKPIPLSRVFKKEDDQ</Hsp_hseq>
      <Hsp_midline>N  VAIKK+   + F+N        REL +MK ++H NII L   F  + S +E   + L++E M  +L Q ++    H+R       + Y ++Q+   + +LH  A + HRD+KP N++V  +  +LK+ DFG A+    +     Y+ +RYYRAPE+I G   YT  +DIWS GC+M E++ G  +FPG   IDQ  +II+ LGTP  + +  + P   NY+E++       F ++ P P  +++ K+ D+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>126.716</Hsp_bit-score>
      <Hsp_score>317</Hsp_score>
      <Hsp_evalue>1.39706e-33</Hsp_evalue>
      <Hsp_query-from>332</Hsp_query-from>
      <Hsp_query-to>856</Hsp_query-to>
      <Hsp_hit-from>50</Hsp_hit-from>
      <Hsp_hit-to>228</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>187</Hsp_align-len>
      <Hsp_qseq>AYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQME--------LDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAG---NSFMMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQLGTP</Hsp_qseq>
      <Hsp_hseq>AIREISLMKELKHENIVRLYDVIHTENKLT------LVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTF--SSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTP</Hsp_hseq>
      <Hsp_midline>A RE+ LMK + H+NI+ L++V   +  L       LV E MD +L + +           L+   + Y  +Q+L G+   H   I+HRDLKP N+++     LK+ DFGLAR  G   N+F  +  VVT +YRAP+V++G   Y+ ++DIWS GCI+ EMI G  LFPGT+  +Q   I + +GTP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>125.561</Hsp_bit-score>
      <Hsp_score>314</Hsp_score>
      <Hsp_evalue>4.15503e-33</Hsp_evalue>
      <Hsp_query-from>119</Hsp_query-from>
      <Hsp_query-to>856</Hsp_query-to>
      <Hsp_hit-from>5</Hsp_hit-from>
      <Hsp_hit-to>231</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>85</Hsp_identity>
      <Hsp_positive>124</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>253</Hsp_align-len>
      <Hsp_qseq>LKRYQNLKPIGSGAQGIVC*WITMAALWRDPASSSSQLGCIDCAAYDIMQNRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQ-----MELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSF-MMTPYVVTRYYRAPEVIL-GMGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQLGTP</Hsp_qseq>
      <Hsp_hseq>LANYKRLEKVGEGTYGVV-----YKALDLRPGQG----------------QRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVH-----SDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTP</Hsp_hseq>
      <Hsp_midline>L  Y+ L+ +G G  G+V       AL   P                    R VA+KK+    +++     A RE+ L+K +   NI+ L+++        +   +YLV E +D +L + ++       L  + +   + Q+  GI + HS  I+HRDLKP N+++  D  LK+ DFGLAR  G      T  +VT +YRAPEV+L G  Y+  VD WS+GCI  EM     +F G   IDQ  KI   LGTP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>126.331</Hsp_bit-score>
      <Hsp_score>316</Hsp_score>
      <Hsp_evalue>9.79564e-33</Hsp_evalue>
      <Hsp_query-from>281</Hsp_query-from>
      <Hsp_query-to>949</Hsp_query-to>
      <Hsp_hit-from>66</Hsp_hit-from>
      <Hsp_hit-to>293</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>124</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>236</Hsp_align-len>
      <Hsp_qseq>AIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANL--------CQVIQMELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDC-TLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQLGTPMAEFMKKLQPTVRNYVENRPKYAGYS---FEKLF</Hsp_qseq>
      <Hsp_hseq>AIKKVP------AHTEYKSRELQILRIADHPNIVKLQYFFTHLSPQDNKVYQHLAMECLPETLQIEINRYVTNKLEMPLKHIRL--YTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSISYICSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLREIAKLLGPPDKRFIFFSNPAYDGPLFSKPLFSGSSQQRFEKYF</Hsp_hseq>
      <Hsp_midline>AIKK+        H +   REL +++  +H NI+ L   FT     +     +L ME +   L           ++M L H R+    YQ+  G+ +LH  G+ HRD+KPSN++V  +   LKI DFG A+   ++     Y+ +R+YRAPE+I+G   YT  +DIW +GC+MGEM+ G  +F G + + Q  +I + LG P   F+    P     + ++P ++G S   FEK F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>122.094</Hsp_bit-score>
      <Hsp_score>305</Hsp_score>
      <Hsp_evalue>1.73515e-30</Hsp_evalue>
      <Hsp_query-from>278</Hsp_query-from>
      <Hsp_query-to>856</Hsp_query-to>
      <Hsp_hit-from>209</Hsp_hit-from>
      <Hsp_hit-to>400</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>197</Hsp_align-len>
      <Hsp_qseq>VAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVI---QMELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQLGTP</Hsp_qseq>
      <Hsp_hseq>VALKKLRLQGEREGFPITSIREIKLLQSFDHPNVSTIKEIM-----VESQKTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKMNSRADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTP</Hsp_hseq>
      <Hsp_midline>VA+KKL    + +     + RE+ L++  +H N+  +  +      +E  + VY++ E  D +L  ++   ++++ H +  +L  Q+L G+++LH   I+HRD+K SNI++ +   LKI DFGLAR   +    T  V+T +YR PE++LG   Y   VD+W  GC++ E+     +F G++ ++Q   I + +GTP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>122.479</Hsp_bit-score>
      <Hsp_score>306</Hsp_score>
      <Hsp_evalue>2.39832e-30</Hsp_evalue>
      <Hsp_query-from>272</Hsp_query-from>
      <Hsp_query-to>865</Hsp_query-to>
      <Hsp_hit-from>84</Hsp_hit-from>
      <Hsp_hit-to>305</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>222</Hsp_align-len>
      <Hsp_qseq>RNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIICLFNV-------FTPQKSLEEFQDVYLVMELMDANLCQVI---QMELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-------------TAGNSFMMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQLGTPMAE</Hsp_qseq>
      <Hsp_hseq>RQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTEE</Hsp_hseq>
      <Hsp_midline>R VA+KK+    +       A RE+ ++K +NHKNII L  +        T   S    +  Y+++  M A+L  V+   ++ L+   +  ++ Q+L G+ ++H A  +HRD+K +NI++  +  LK+ DFGLAR              AG+    T  VVTR+YRAPE++LG   YT  VDIW VGC+  E      +  G   IDQ + I + LGTP  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>119.783</Hsp_bit-score>
      <Hsp_score>299</Hsp_score>
      <Hsp_evalue>1.9155e-29</Hsp_evalue>
      <Hsp_query-from>113</Hsp_query-from>
      <Hsp_query-to>859</Hsp_query-to>
      <Hsp_hit-from>33</Hsp_hit-from>
      <Hsp_hit-to>305</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>84</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>281</Hsp_align-len>
      <Hsp_qseq>TVLKRYQNLKPIGSGAQGIVC*WITMAALWRDPASSSSQLGCIDCAAYDIMQNR------NVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMELDHER--------MSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVV-----------------KSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGY-TENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQLGTPM</Hsp_qseq>
      <Hsp_hseq>TLSDRYQLIEKLGAGSFGCVTLAKAQFPLSNILGKQHDIRGTLMDQPKNGHQNYITKTQGVVAIKTMMTKLHTLQDYTRVREIKFILAIPANDHLIQIFEVFIDSENYQ----LHIVMECMEQNLYQMMK----HRRRRVFSIPSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVENKNPYTAYVSTRWYRSPEILLRSGYYSKPLDIWAFGCVAVEVTVFRALFPGANEIDQIWKILEVLGTPI</Hsp_hseq>
      <Hsp_midline>T+  RYQ ++ +G+G+ G V        L           G +     +  QN        VAIK +           R      ++    + ++I +F VF   ++ +    +++VME M+ NL Q+++    H R        +  ++ Q+L G+KH+H     HRDLKP NI++                 + +  +K+ DFGLAR   N    T YV TR+YR+PE++L  GY ++ +DIW+ GC+  E+     LFPG + IDQ  KI+E LGTP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>111.309</Hsp_bit-score>
      <Hsp_score>277</Hsp_score>
      <Hsp_evalue>5.67985e-28</Hsp_evalue>
      <Hsp_query-from>269</Hsp_query-from>
      <Hsp_query-to>856</Hsp_query-to>
      <Hsp_hit-from>30</Hsp_hit-from>
      <Hsp_hit-to>224</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>201</Hsp_align-len>
      <Hsp_qseq>NRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQ---MELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLART-AGNSFMMTPYVVTRYYRAPEVILGMG-YTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQLGTP</Hsp_qseq>
      <Hsp_hseq>GRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNVIELIDIFM------AYDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTP</Hsp_hseq>
      <Hsp_midline> R +AIK++            A RE+  ++ + H N+I L ++F        + ++ LV+E +  +L  VI+   +      +   +   L G+ H H   I+HRDLKP+N++   D  +K+ DFGLAR       ++T  VVTR+YRAPE++ G   YT  +DIWSVG I  E++      PG + +DQ       LGTP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>112.464</Hsp_bit-score>
      <Hsp_score>280</Hsp_score>
      <Hsp_evalue>3.59796e-27</Hsp_evalue>
      <Hsp_query-from>323</Hsp_query-from>
      <Hsp_query-to>922</Hsp_query-to>
      <Hsp_hit-from>201</Hsp_hit-from>
      <Hsp_hit-to>409</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>122</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>AKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMELDHER-------MSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPY-----VVTRYYRAPEVILGM-GYTENVDIWSVGCIMGEMIRGAVLFPGTD-----------HIDQWNKIIEQLGTPMAEFMKKLQPTVRNYVENRPKY</Hsp_qseq>
      <Hsp_hseq>SQSACREMALCRELHNKHLTTLVEIFLERKC------VHMVYEYAEHDLLQIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDGCVKIGDLGLARKFHN-MLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELIGLQPIFKGEEAKLDSKKTVPFQVNQLQRILEVLGTP----DQKIWP----YLEKYPEY</Hsp_hseq>
      <Hsp_midline>++ A RE+ L + +++K++  L  +F  +K       V++V E  + +L Q+I      E+       +  +++Q+L G+ +LH   ++HRDLKP+NI+V  D  +KI D GLAR   N  + T Y     VVT +YRAPE++LG   YT  VD+WSVGCI  E+I    +F G +            ++Q  +I+E LGTP     +K+ P    Y+E  P+Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YDL079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:312951:314748:-1 gene:YDL079C transcript:YDL079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRK1 description:Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication [Source:SGD;Acc:S000002237]</Hit_def>
  <Hit_accession>YDL079C</Hit_accession>
  <Hit_len>501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>110.153</Hsp_bit-score>
      <Hsp_score>274</Hsp_score>
      <Hsp_evalue>1.46935e-26</Hsp_evalue>
      <Hsp_query-from>260</Hsp_query-from>
      <Hsp_query-to>904</Hsp_query-to>
      <Hsp_hit-from>184</Hsp_hit-from>
      <Hsp_hit-to>400</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>120</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>228</Hsp_align-len>
      <Hsp_qseq>IMQNRNVAIKKL--SRPFQNQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYL--VMELMDANLCQVI------QMELDHERMSYLIYQMLCGIKHLHSAG-IIHRDLKPSNIVVK-SDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQLGTPMAEFMKKLQPTVRNYV</Hsp_qseq>
      <Hsp_hseq>IETNQKVAIKKVLQDRRYKN--------RELETMKMLCHPNTVGLQYYFYEK---DEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKIMGIPTKDEISGMNPNYEDHV</Hsp_hseq>
      <Hsp_midline>I  N+ VAIKK+   R ++N        REL  MK + H N + L   F  +   +E  +VYL  V++ M  +L Q +      +M++    + +  YQ+   + +LH+   I HRD+KP N++V  +  + KI DFG A+          Y+ +RYYRAPE++ G   Y+  VD+WS  C++ E++ G  LF G   IDQ  +II+ +G P  + +  + P   ++V</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>102.449</Hsp_bit-score>
      <Hsp_score>254</Hsp_score>
      <Hsp_evalue>1.99578e-24</Hsp_evalue>
      <Hsp_query-from>341</Hsp_query-from>
      <Hsp_query-to>850</Hsp_query-to>
      <Hsp_hit-from>86</Hsp_hit-from>
      <Hsp_hit-to>266</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>181</Hsp_align-len>
      <Hsp_qseq>ELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVY---LVMELMDANLCQVIQMELDH------ERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNI-VVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVIL-GMGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQLG</Hsp_qseq>
      <Hsp_hseq>ELEILQNIRHPNLVTLEFFFESHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGIAKVCDFGSAQRLDDNTELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPLFKGDSANSQLEEIAKLLG</Hsp_hseq>
      <Hsp_midline>EL +++ + H N++ L   F    + ++   +Y    VME +   L   I    D+      + +    +Q+L  +  LHS  I H DLKPSNI ++ S    K+ DFG A+   ++  +  Y  +R+YRAPE++L    YT  +DIWS+GCI+GEMI+G  LF G     Q  +I + LG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>103.605</Hsp_bit-score>
      <Hsp_score>257</Hsp_score>
      <Hsp_evalue>4.83992e-24</Hsp_evalue>
      <Hsp_query-from>311</Hsp_query-from>
      <Hsp_query-to>886</Hsp_query-to>
      <Hsp_hit-from>428</Hsp_hit-from>
      <Hsp_hit-to>609</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>208</Hsp_align-len>
      <Hsp_qseq>NQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLI----YQMLCGIKHLHSAGIIHRDLKPSNIVV--KSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQLGTP----------MAEFMKKLQP</Hsp_qseq>
      <Hsp_hseq>NKHHFLRMYDSFV------HKNHLCL------------------VFELLSNNLYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPELKIIDFGSSCEEARTVYT--YIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAELFLGIPIFPGASEYNQLTRIIDTLGYPPSWMIDMGKNSGKFMKKLAP</Hsp_hseq>
      <Hsp_midline>N+ H  R Y   V      HKN +CL                  V EL+  NL ++++    H     LI     Q+L  +  L  + +IH DLKP NI++       LKI+DFG +     +     Y+ +R+YRAPE+ILG+ Y+ ++D+WS+GCI+ E+  G  +FPG    +Q  +II+ LG P            +FMKKL P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.1301</Hsp_bit-score>
      <Hsp_score>235</Hsp_score>
      <Hsp_evalue>3.64812e-21</Hsp_evalue>
      <Hsp_query-from>125</Hsp_query-from>
      <Hsp_query-to>787</Hsp_query-to>
      <Hsp_hit-from>619</Hsp_hit-from>
      <Hsp_hit-to>810</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>RYQNLKPIGSGAQGIVC*WITMAALWRDPASSSSQLGCIDCAAYDIMQNRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDA-NLCQVIQM-ELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGL-ARTAGNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRG</Hsp_qseq>
      <Hsp_hseq>KYANLVKIGQGASGGVY------------------------TAYEIGTNVSVAIKQMN--LEKQPKKELIINEILVMKGSKHPNIVNFIDSYVLKG------DLWVIMEYMEGGSLTDVVTHCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEG</Hsp_hseq>
      <Hsp_midline>+Y NL  IG GA G V                          AY+I  N +VAIK+++   + Q   +    E+++MK   H NI+   + +  +       D++++ME M+  +L  V+    L   ++  +  + L G++ LHS G++HRD+K  NI++  +  +K+ DFG  A+    +   T  V T Y+ APEV+    Y   VDIWS+G ++ EMI G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.5893</Hsp_bit-score>
      <Hsp_score>231</Hsp_score>
      <Hsp_evalue>1.0612e-20</Hsp_evalue>
      <Hsp_query-from>338</Hsp_query-from>
      <Hsp_query-to>910</Hsp_query-to>
      <Hsp_hit-from>243</Hsp_hit-from>
      <Hsp_hit-to>445</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>215</Hsp_align-len>
      <Hsp_qseq>RELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDA-NLCQVIQME--LDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSD--CTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMG-------------YTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQLG------TPMAEFMKKLQPTVRNYVEN</Hsp_qseq>
      <Hsp_hseq>RELEVLQKLNHPRIVRLKGFY------EDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQ----DQLYKQIGRGSYHEGPLKDF--RISEEARDFIDS</Hsp_hseq>
      <Hsp_midline>REL +++ +NH  I+ L   +      E+ +  Y+VME +   +L   +     +  +    +  Q+L  IK++HS GI HRDLKP NI+++ D    +KI DFGLA+  GN   M  +  T  Y APEVI G               Y+  VD+WS+GC++  ++ G + F G+      +++ +Q+G       P+ +F  ++    R+++++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.2041</Hsp_bit-score>
      <Hsp_score>230</Hsp_score>
      <Hsp_evalue>1.51735e-20</Hsp_evalue>
      <Hsp_query-from>338</Hsp_query-from>
      <Hsp_query-to>799</Hsp_query-to>
      <Hsp_hit-from>76</Hsp_hit-from>
      <Hsp_hit-to>227</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>RELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMELDH----ERMSYLIY-QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYTE-NVDIWSVGCIMGEMIRGAVLF</Hsp_qseq>
      <Hsp_hseq>REIVIMKLLSHPNVLSLYDVW------ETNNNLYLILEY--AEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPF</Hsp_hseq>
      <Hsp_midline>RE+V+MK ++H N++ L++V+      E   ++YL++E   A   ++  + +DH    ER +   + Q++ GI + H+ GI+HRDLKP N+++ S   +KI DFG+A    ++ ++     + +Y APE++ G+ Y     D+WS G I+  ++ G + F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>92.0485</Hsp_bit-score>
      <Hsp_score>227</Hsp_score>
      <Hsp_evalue>3.37254e-20</Hsp_evalue>
      <Hsp_query-from>338</Hsp_query-from>
      <Hsp_query-to>811</Hsp_query-to>
      <Hsp_hit-from>80</Hsp_hit-from>
      <Hsp_hit-to>235</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>163</Hsp_align-len>
      <Hsp_qseq>RELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMEL----DHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYTE-NVDIWSVGCIMGEMIRGAVLFPGTD</Hsp_qseq>
      <Hsp_hseq>REIIIMKLLNHPNVLRLYDVW------ETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFF-RQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEED</Hsp_hseq>
      <Hsp_midline>RE+++MK +NH N++ L++V+      E   D+YLV+E  +      + +E     +HE + +   Q++ G+ + H+ GI+HRDLKP N+++     +KI DFG+A       ++     + +Y APE++ G+ Y     D+WS G I+  ++ G + F   D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>91.2781</Hsp_bit-score>
      <Hsp_score>225</Hsp_score>
      <Hsp_evalue>5.29153e-20</Hsp_evalue>
      <Hsp_query-from>278</Hsp_query-from>
      <Hsp_query-to>904</Hsp_query-to>
      <Hsp_hit-from>591</Hsp_hit-from>
      <Hsp_hit-to>802</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>220</Hsp_align-len>
      <Hsp_qseq>VAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDA-NLCQVIQ---------MELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGL-ARTAGNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQLGTPMAEFMKKLQPTVRNYV</Hsp_qseq>
      <Hsp_hseq>VAIKQMV--LSKQPRKELIVNEILVMKDSRHKNIVNFLEAY-----LRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKAL-YLIATNGTPKLKHPESLSLEIKRFL</Hsp_hseq>
      <Hsp_midline>VAIK++      Q   +    E+++MK   HKNI+     +     L    D+++VME M+  +L  +I+           L   +++Y++ +   G+K LH   IIHRD+K  N+++ +   +KI DFG  AR           V T Y+ APEV+    Y E +D+WS+G +  EM+ G   +   D +     +I   GTP  +  + L   ++ ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.5817</Hsp_bit-score>
      <Hsp_score>218</Hsp_score>
      <Hsp_evalue>2.26034e-19</Hsp_evalue>
      <Hsp_query-from>281</Hsp_query-from>
      <Hsp_query-to>847</Hsp_query-to>
      <Hsp_hit-from>241</Hsp_hit-from>
      <Hsp_hit-to>430</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>196</Hsp_align-len>
      <Hsp_qseq>AIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMEL-------DHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQL</Hsp_qseq>
      <Hsp_hseq>ALKTINTMNTDPEYQKQIFRELQFNKSFKSDYIVQYYGMFTDEQS----SSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFGVSGEAVNSLAMT-FTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRFPFE-SDKITQNVAPIELL</Hsp_hseq>
      <Hsp_midline>A+K ++    +  + K+ +REL   K      I+  + +FT ++S      +Y+ ME M     +     L           +  +   +L G+ +LH   +IHRD+KP NI++     +K+ DFG++  A NS  MT +  T +Y APE I G  Y+   D+WS+G  + E+  G   F  +D I Q    IE L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.8113</Hsp_bit-score>
      <Hsp_score>216</Hsp_score>
      <Hsp_evalue>3.97463e-19</Hsp_evalue>
      <Hsp_query-from>272</Hsp_query-from>
      <Hsp_query-to>769</Hsp_query-to>
      <Hsp_hit-from>224</Hsp_hit-from>
      <Hsp_hit-to>411</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>190</Hsp_align-len>
      <Hsp_qseq>RNVAIKKLSRPFQNQTHAKRAYREL--VLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMD-ANLCQVIQME--LDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVV-------------------KSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIM</Hsp_qseq>
      <Hsp_hseq>QQVAVKIFHAQQNDDQKKNKQFREETNILMR-VQHPNIVNLLDSFVEPISKSQIQK-YLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVIL</Hsp_hseq>
      <Hsp_midline>+ VA+K       +     + +RE   +LM+ V H NI+ L + F    S  + Q  YLV+E +D   L + I  +  L  +    L  Q+L G+K+LH   IIHRD+KP NI++                   + D  +KI DFGLA+  G          T  Y APEV+   GYT  VD+WS G I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.8113</Hsp_bit-score>
      <Hsp_score>216</Hsp_score>
      <Hsp_evalue>4.47283e-19</Hsp_evalue>
      <Hsp_query-from>326</Hsp_query-from>
      <Hsp_query-to>868</Hsp_query-to>
      <Hsp_hit-from>197</Hsp_hit-from>
      <Hsp_hit-to>385</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>195</Hsp_align-len>
      <Hsp_qseq>KRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQME---LDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSF-----------MMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQLGTPMAEF</Hsp_qseq>
      <Hsp_hseq>ERTFAERSILSEIEHPNIVKLFYSFHDNSKL------YLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIPF</Hsp_hseq>
      <Hsp_midline>+R + E  ++  + H NI+ LF  F     L      YL+++ +          E   LD   +S+   ++ C ++ LH+ G+++RDLKP N ++     L + DFGL++ + N              +   + T  Y APE++LG  Y++N D +S+GC++ +M+ G   + G++H    NKI +    P   F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YIL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:287790:288908:-1 gene:YIL035C transcript:YIL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA1 description:Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000001297]</Hit_def>
  <Hit_accession>YIL035C</Hit_accession>
  <Hit_len>372</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.9593</Hsp_bit-score>
      <Hsp_score>206</Hsp_score>
      <Hsp_evalue>3.49596e-18</Hsp_evalue>
      <Hsp_query-from>368</Hsp_query-from>
      <Hsp_query-to>880</Hsp_query-to>
      <Hsp_hit-from>130</Hsp_hit-from>
      <Hsp_hit-to>297</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>174</Hsp_align-len>
      <Hsp_qseq>HKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVV-KSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMG-YTENVDIWSVGCIMGEMI-RGAVLFPGTDHIDQWNKIIEQLGTPMAEFMKKL</Hsp_qseq>
      <Hsp_hseq>HANIIHLFDIIKDPIS----KTPALVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGT--SDFEKYL</Hsp_hseq>
      <Hsp_midline>H NII LF++     S    +   LV E +D    +++  +L    + + ++++L  + + HS GI+HRD+KP N+++   +  L+++D+GLA     +      V +R+++ PE+++    Y  ++D+WS G ++  MI +    F GT + DQ  KI++ LGT  ++F K L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.1149</Hsp_bit-score>
      <Hsp_score>209</Hsp_score>
      <Hsp_evalue>3.54177e-18</Hsp_evalue>
      <Hsp_query-from>320</Hsp_query-from>
      <Hsp_query-to>802</Hsp_query-to>
      <Hsp_hit-from>261</Hsp_hit-from>
      <Hsp_hit-to>421</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>168</Hsp_align-len>
      <Hsp_qseq>HAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMEL-------DHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLFP</Hsp_qseq>
      <Hsp_hseq>YQKQIFRELQFNRSFQSEYIVRYYGMFTD----DENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVSGEAVNS-LATTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANGK--FP</Hsp_hseq>
      <Hsp_midline>+ K+ +REL   +    + I+  + +FT     +E   +Y+ ME M       I   L         + +  +   +L G+ +LH   +IHRD+KP NI++  +  +K+ DFG++  A NS + T +  T +Y APE I G  Y+   D+WS+G  + E+  G   FP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.5001</Hsp_bit-score>
      <Hsp_score>210</Hsp_score>
      <Hsp_evalue>5.52053e-18</Hsp_evalue>
      <Hsp_query-from>224</Hsp_query-from>
      <Hsp_query-to>799</Hsp_query-to>
      <Hsp_hit-from>122</Hsp_hit-from>
      <Hsp_hit-to>315</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>200</Hsp_align-len>
      <Hsp_qseq>SQLGCIDCAAYDIMQNRNVAIKKL-SRPFQN--QTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLC---QVIQMELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVV-KSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYTEN-VDIWSVGCIMGEMIRGAVLF</Hsp_qseq>
      <Hsp_hseq>SNNGTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVW------ENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPF</Hsp_hseq>
      <Hsp_midline>S  G +  +    M   NV+   + SR   N  QT+     RE+V+MK ++H N++ LF V+      E   ++YLV+E +D        V + +L      +   Q++ G+ + HS  I HRDLKP N+++ K +  +KI DFG+A     + ++     + +Y +PE+++G  Y     D+WS G ++  ++ G + F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YOR061W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:441534:442553:1 gene:YOR061W transcript:YOR061W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA2 description:Alpha&apos; catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000005587]</Hit_def>
  <Hit_accession>YOR061W</Hit_accession>
  <Hit_len>339</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.1889</Hsp_bit-score>
      <Hsp_score>204</Hsp_score>
      <Hsp_evalue>5.7292e-18</Hsp_evalue>
      <Hsp_query-from>260</Hsp_query-from>
      <Hsp_query-to>853</Hsp_query-to>
      <Hsp_hit-from>70</Hsp_hit-from>
      <Hsp_hit-to>262</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>213</Hsp_align-len>
      <Hsp_qseq>IMQNRNVAIKKLSRPFQNQTHAKRAYREL-VLMKCVNHKNIICLFNVF------TPQKSLEE-----FQDVYLVMELMDANLCQVIQMELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVK-SDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMG-YTENVDIWSVGCIMGEMI-RGAVLFPGTDHIDQWNKIIEQLGT</Hsp_qseq>
      <Hsp_hseq>IVNNQKCVIKVL-KPVK----MKKIYRELKILTNLTGGPNVVGLYDIVQDADSKIPALIFEEIKNVDFRTLYPTFKLPD---------------IQYYFTQLLIALDYCHSMGIMHRDVKPQNVMIDPTERKLRLIDWGLAEFYHPGVDYNVRVASRYHKGPELLVNLNQYDYSLDLWSVGCMLAAIVFKKEPFFKGSSNPDQLVKIATVLGT</Hsp_hseq>
      <Hsp_midline>I+ N+   IK L +P +     K+ YREL +L       N++ L+++        P    EE     F+ +Y   +L D               + Y   Q+L  + + HS GI+HRD+KP N+++  ++  L+++D+GLA            V +RY++ PE+++ +  Y  ++D+WSVGC++  ++ +    F G+ + DQ  KI   LGT</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>84.7297</Hsp_bit-score>
      <Hsp_score>208</Hsp_score>
      <Hsp_evalue>6.31778e-18</Hsp_evalue>
      <Hsp_query-from>278</Hsp_query-from>
      <Hsp_query-to>787</Hsp_query-to>
      <Hsp_hit-from>403</Hsp_hit-from>
      <Hsp_hit-to>578</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>188</Hsp_align-len>
      <Hsp_qseq>VAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVI------------QMELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGL------ARTAGNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRG</Hsp_qseq>
      <Hsp_hseq>VAIKQIR--LSEQPKKQLIMNELLVMNDSRQENIVNFLEAY-----IIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMVGTP-----YWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEG</Hsp_hseq>
      <Hsp_midline>VAIK++      Q   +    EL++M     +NI+     +     + + ++++++ME M+      I               L+  +M+Y++ +   G+K LH+  IIHRD+K  NI++ S   +KI DFG        R+   + + TP     Y+ APE++   GY E VD+WS+G ++ EMI G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.1889</Hsp_bit-score>
      <Hsp_score>204</Hsp_score>
      <Hsp_evalue>2.99024e-17</Hsp_evalue>
      <Hsp_query-from>236</Hsp_query-from>
      <Hsp_query-to>787</Hsp_query-to>
      <Hsp_hit-from>1192</Hsp_hit-from>
      <Hsp_hit-to>1376</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>192</Hsp_align-len>
      <Hsp_qseq>CIDCAAYDIMQNRNVAIKKLSRPFQNQTHAKRAYR-ELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVY-LVME-LMDANLCQVIQM--ELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVV--TRYYRAPEVI-LGMGYTENVDIWSVGCIMGEMIRG</Hsp_qseq>
      <Hsp_hseq>CLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYL-------GFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAG</Hsp_hseq>
      <Hsp_midline>C++    ++M  + V + K S   +       A R E+  +K ++H NI+            E   ++Y L +E +   ++  +I+M    D   + +L  Q+L G+ +LHS GI+HRD+K  N+++  D   KI DFG++R + + +  +   +  T ++ APE++    GY+  VDIWS+GCI+ EM  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.2629</Hsp_bit-score>
      <Hsp_score>199</Hsp_score>
      <Hsp_evalue>5.80173e-17</Hsp_evalue>
      <Hsp_query-from>227</Hsp_query-from>
      <Hsp_query-to>847</Hsp_query-to>
      <Hsp_hit-from>193</Hsp_hit-from>
      <Hsp_hit-to>418</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>232</Hsp_align-len>
      <Hsp_qseq>QLGCIDCA-------AYDIMQNRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVN-HKNIICLFNVFTPQKSLEEFQDVYLVMELMD-ANLCQVIQME---------------LDHERMSYLIYQMLCGIKHLHSA-GIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQL</Hsp_qseq>
      <Hsp_hseq>QLGKIGAGNSGTVVKALHVPDSKIVAKKTIPVEQNNSTIINQLVRELSIVKNVKPHENIITFYGAYYNQHINNE---IIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKLINSIADT-FVGTSTYMSPERIQGNVYSIKGDVWSLGLMIIELVTGE--FPLGGHNDTPDGILDLL</Hsp_hseq>
      <Hsp_midline>QLG I          A  +  ++ VA K +     N T   +  REL ++K V  H+NII  +  +  Q    E   + ++ME  D  +L +++ +                 +   +S + Y +L G+ HL+    IIHRD+KPSN+++ S   +K+ DFG+++   NS   T +V T  Y +PE I G  Y+   D+WS+G ++ E++ G   FP   H D  + I++ L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.6481</Hsp_bit-score>
      <Hsp_score>200</Hsp_score>
      <Hsp_evalue>8.25446e-17</Hsp_evalue>
      <Hsp_query-from>341</Hsp_query-from>
      <Hsp_query-to>841</Hsp_query-to>
      <Hsp_hit-from>228</Hsp_hit-from>
      <Hsp_hit-to>403</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>183</Hsp_align-len>
      <Hsp_qseq>ELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELM-DANLCQVIQM--ELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR--TAGNSFMMTP----------YVVTRYYRAPEVILGMGYTE-NVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIE</Hsp_qseq>
      <Hsp_hseq>KTALQKLNNSPSVVRLFSTFQDESSL------YFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPE-LLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMK</Hsp_hseq>
      <Hsp_midline>+  L K  N  +++ LF+ F  + SL      Y ++E   + +   +++    LD     Y   Q++  I +LHS GIIHRD+KP NI++  +  +K+ DFG A+     N+ +  P          +V T  Y +PE +L   +T+   DIW+ GCI+ +MI G   F  T+    + K+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YDL028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:400997:403291:-1 gene:YDL028C transcript:YDL028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MPS1 description:Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]</Hit_def>
  <Hit_accession>YDL028C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.2629</Hsp_bit-score>
      <Hsp_score>199</Hsp_score>
      <Hsp_evalue>9.09767e-17</Hsp_evalue>
      <Hsp_query-from>434</Hsp_query-from>
      <Hsp_query-to>787</Hsp_query-to>
      <Hsp_hit-from>512</Hsp_hit-from>
      <Hsp_hit-to>650</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>140</Hsp_align-len>
      <Hsp_qseq>VYLVMELMDANLCQVIQ----MELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGN---SFMMTPYVVTRYYRAPEVILGMGYTEN---------------VDIWSVGCIMGEMIRG</Hsp_qseq>
      <Hsp_hseq>LYLIMECGDHDLSQILNQRSGMPLDFNFVRFYTKEMLLCIKVVHDAGIVHSDLKPANFVLVKGI-LKIIDFGIANAVPEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYG</Hsp_hseq>
      <Hsp_midline>+YL+ME  D +L Q++     M LD   + +   +ML  IK +H AGI+H DLKP+N V+     LKI+DFG+A        +      + T  Y APE ++ M YT+N                D+WS GCI+ +MI G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.8777</Hsp_bit-score>
      <Hsp_score>198</Hsp_score>
      <Hsp_evalue>1.0205e-16</Hsp_evalue>
      <Hsp_query-from>326</Hsp_query-from>
      <Hsp_query-to>811</Hsp_query-to>
      <Hsp_hit-from>124</Hsp_hit-from>
      <Hsp_hit-to>285</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>169</Hsp_align-len>
      <Hsp_qseq>KRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELM-DANLCQVIQME--LDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVV--TRYYRAPEVILGM--GYTENVDIWSVGCIMGEMIRGAVLFPGTD</Hsp_qseq>
      <Hsp_hseq>KKLLSEIQIHKSMSHPNIVQFIDCF------EDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANE-SERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARD</Hsp_hseq>
      <Hsp_midline>K+   E+ + K ++H NI+   + F      E+  +VY+++E+  + +L ++++    L    + +   Q+   IK++HS  +IHRDLK  NI   S+  LKI DFGLA    N      Y +  T  Y APEV++G   G++  VDIWS+G ++  ++ G   F   D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.4925</Hsp_bit-score>
      <Hsp_score>197</Hsp_score>
      <Hsp_evalue>1.16783e-16</Hsp_evalue>
      <Hsp_query-from>251</Hsp_query-from>
      <Hsp_query-to>844</Hsp_query-to>
      <Hsp_hit-from>67</Hsp_hit-from>
      <Hsp_hit-to>291</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>229</Hsp_align-len>
      <Hsp_qseq>AYDIMQNRNVAIKKLSR-------PFQNQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMD---ANLCQVIQMELDHERMSYLIYQ--------MLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA----------RTAGNSFMMTPYVVTRYYRAPEVILG---MGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQ</Hsp_qseq>
      <Hsp_hseq>ARDLGTGALVAIKILNRFEKRSGYSLQLKVENPRVNQEIEVMKRCHHENVVELYEILNDPESTK----VYLVLEYCSRGPVKWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPFNANSGLELFDSIINK</Hsp_hseq>
      <Hsp_midline>A D+     VAIK L+R         Q +    R  +E+ +MK  +H+N++ L+ +    +S +    VYLV+E         C   +ME+     S L +Q        ++ G+++LHS GI HRD+KPSN+++ S+ T+KI DFG+A          +++    + +  + T  + APE+         +  +DIWS+G  +  ++ G + F     ++ ++ II +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.1814</Hsp_bit-score>
      <Hsp_score>191</Hsp_score>
      <Hsp_evalue>4.01679e-16</Hsp_evalue>
      <Hsp_query-from>251</Hsp_query-from>
      <Hsp_query-to>835</Hsp_query-to>
      <Hsp_hit-from>64</Hsp_hit-from>
      <Hsp_hit-to>278</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>218</Hsp_align-len>
      <Hsp_qseq>AYDIMQNRNVAIK-KLSRPFQ-NQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNI--VVKSDCT-LKILDFGLART-AGNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCI-----------MGEMIRG------AVLFPGTDHIDQWNKI</Hsp_qseq>
      <Hsp_hseq>ARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVD---AVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSPFIAESVEGFMEECTASRYPVTFHMPYWDNI</Hsp_hseq>
      <Hsp_midline>A  +  N +VAIK  L +  Q N    +  Y EL +++ ++H NI+   + F  +        +    EL D  L +    E+D      +I Q+L  ++++HS  ++HRDLKP N+  V KS+ + L I DFG+A+   G   ++     +  Y APEV+   G+ +  DIWS+G I           + E + G      A  +P T H+  W+ I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.5666</Hsp_bit-score>
      <Hsp_score>192</Hsp_score>
      <Hsp_evalue>5.43703e-16</Hsp_evalue>
      <Hsp_query-from>413</Hsp_query-from>
      <Hsp_query-to>844</Hsp_query-to>
      <Hsp_hit-from>413</Hsp_hit-from>
      <Hsp_hit-to>560</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>153</Hsp_align-len>
      <Hsp_qseq>SLEEFQDVYLVMELMDAN-LCQVIQME--LDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR------TAGNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQ</Hsp_qseq>
      <Hsp_hseq>SFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPE-----YLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQE</Hsp_hseq>
      <Hsp_midline>S +  + +Y V+  ++   L   +Q E   D  R  +   ++LC + +LH   +++RDLKP NI++     + + DFGL +         ++F  TP      Y APE++LG+GYT+ VD W++G ++ EM+ G   +   D    + KI+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.9518</Hsp_bit-score>
      <Hsp_score>193</Hsp_score>
      <Hsp_evalue>5.55708e-16</Hsp_evalue>
      <Hsp_query-from>278</Hsp_query-from>
      <Hsp_query-to>781</Hsp_query-to>
      <Hsp_hit-from>51</Hsp_hit-from>
      <Hsp_hit-to>212</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>VAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMEL-MDANLCQVIQME---LDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMI</Hsp_qseq>
      <Hsp_hseq>VAIKEVV--YENDEELNDIMAEISLLKNLNHNNIVKYHGFI--RKSYE----LYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVS-TIVNSSALT-LAGTLNWMAPEILGNRGASTLSDIWSLGATVVEML</Hsp_hseq>
      <Hsp_midline>VAIK++   ++N         E+ L+K +NH NI+        +KS E    +Y+++E   + +L ++I      L        + Q L G+K+LH  G+IHRD+K +NI++ +D T+K+ DFG++ T  NS  +T    T  + APE++   G +   DIWS+G  + EM+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.0258</Hsp_bit-score>
      <Hsp_score>188</Hsp_score>
      <Hsp_evalue>1.39514e-15</Hsp_evalue>
      <Hsp_query-from>434</Hsp_query-from>
      <Hsp_query-to>787</Hsp_query-to>
      <Hsp_hit-from>89</Hsp_hit-from>
      <Hsp_hit-to>213</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>125</Hsp_align-len>
      <Hsp_qseq>VYLVMELMDANLCQVIQME-----LDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGM--GYTENVDIWSVGCIMGEMIRG</Hsp_qseq>
      <Hsp_hseq>MWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKG</Hsp_hseq>
      <Hsp_midline>+++VME      C  +        L  E++S++I+++  G+K+LH    IHRD+K +NI++  +  +K+ DFG++    ++     +V T Y+ APEV+     GY E  DIWS+G    E+++G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.411</Hsp_bit-score>
      <Hsp_score>189</Hsp_score>
      <Hsp_evalue>1.77128e-15</Hsp_evalue>
      <Hsp_query-from>392</Hsp_query-from>
      <Hsp_query-to>868</Hsp_query-to>
      <Hsp_hit-from>770</Hsp_hit-from>
      <Hsp_hit-to>942</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>179</Hsp_align-len>
      <Hsp_qseq>NVFTPQKSLEEFQDVYLVMEL-MDANLCQVIQME-LDHERMSY--LIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTA---------------GNSFMMTPYVVTRYYRAPEVILGMG-YTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQLGTPMAEF</Hsp_qseq>
      <Hsp_hseq>NFVKPMTAVKKKSTLFIQMEYCENRTLYDLIHSENLNQQRDEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNVKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVLDGTGHYNEKIDMYSLGIIFFEMI-----YPFSTGMERVN-ILKKLRSVSIEF</Hsp_hseq>
      <Hsp_midline>N   P  ++++   +++ ME   +  L  +I  E L+ +R  Y  L  Q+L  + ++HS GIIHRDLKP NI +     +KI DFGLA+                 G+S  +T  + T  Y A EV+ G G Y E +D++S+G I  EMI     +P +  +++ N I+++L +   EF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.0258</Hsp_bit-score>
      <Hsp_score>188</Hsp_score>
      <Hsp_evalue>1.90026e-15</Hsp_evalue>
      <Hsp_query-from>413</Hsp_query-from>
      <Hsp_query-to>844</Hsp_query-to>
      <Hsp_hit-from>410</Hsp_hit-from>
      <Hsp_hit-to>557</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>148</Hsp_align-len>
      <Hsp_qseq>SLEEFQDVYLVMELMDAN-LCQVIQME--LDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-TAGNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQ</Hsp_qseq>
      <Hsp_hseq>SFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQ</Hsp_hseq>
      <Hsp_midline>S +  + +YLV+  ++   L   +Q E      R  + I ++LC +  LH   +I+RDLKP NI++     + + DFGL +    ++     +  T  Y APE++LG GYT+ VD W++G ++ EM+ G   +   +    + KI++Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YLL019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:105686:107899:-1 gene:YLL019C transcript:YLL019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KNS1 description:Protein kinase involved in negative regulation of PolIII transcription; effector kinase of the TOR signaling pathway and phosphorylates Rpc53p to regulate ribosome and tRNA biosynthesis; member of the LAMMER family of protein kinases, which are serine/threonine kinases also capable of phosphorylating tyrosine residues; capable of autophosphorylation [Source:SGD;Acc:S000003942]</Hit_def>
  <Hit_accession>YLL019C</Hit_accession>
  <Hit_len>737</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.6406</Hsp_bit-score>
      <Hsp_score>187</Hsp_score>
      <Hsp_evalue>2.15686e-15</Hsp_evalue>
      <Hsp_query-from>344</Hsp_query-from>
      <Hsp_query-to>859</Hsp_query-to>
      <Hsp_hit-from>377</Hsp_hit-from>
      <Hsp_hit-to>564</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>204</Hsp_align-len>
      <Hsp_qseq>LVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDC--------------------------------TLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQLGTPM</Hsp_qseq>
      <Hsp_hseq>LLLRECFDYKNHICLVTDLY-GRSIYDF-------------MCSNGIARFPGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENILICDETHIAQKLPLKTVQSLSKRRREASKGKRKILKNPEIKIIDFGSA--IFHYEYHPPVISTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVIGESLYPIHENLEHMAMMQRINGTPF</Hsp_hseq>
      <Hsp_midline>L+L +C ++KN ICL       +S+ +F             +C           +  +  Q++  +  LH  GIIH DLKP NI++  +                                  +KI+DFG A    +     P + TR+YRAPE++LG+G++   DIWS+ C++ E++ G  L+P  ++++    +    GTP </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.6406</Hsp_bit-score>
      <Hsp_score>187</Hsp_score>
      <Hsp_evalue>2.32149e-15</Hsp_evalue>
      <Hsp_query-from>326</Hsp_query-from>
      <Hsp_query-to>844</Hsp_query-to>
      <Hsp_hit-from>367</Hsp_hit-from>
      <Hsp_hit-to>557</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>197</Hsp_align-len>
      <Hsp_qseq>KRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMEL-MDANLCQVIQME----LDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNS-------------------FMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQ</Hsp_qseq>
      <Hsp_hseq>KRVLTEQEILATSDHPFIVTLYHSFQTKDYL------YLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTK</Hsp_hseq>
      <Hsp_midline>KR   E  ++   +H  I+ L++ F  +  L      YL ME  M     + +Q      +  E   +   +++  +++LH  G I+RDLKP NI++     + + DF L+  A  S                   F    +V T  Y APEVI G G+T  VD W++G ++ EM+ G   F G +  + ++ I+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.2554</Hsp_bit-score>
      <Hsp_score>186</Hsp_score>
      <Hsp_evalue>3.12556e-15</Hsp_evalue>
      <Hsp_query-from>413</Hsp_query-from>
      <Hsp_query-to>922</Hsp_query-to>
      <Hsp_hit-from>481</Hsp_hit-from>
      <Hsp_hit-to>654</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>175</Hsp_align-len>
      <Hsp_qseq>SLEEFQDVYLVMELMDAN-LCQVIQME--LDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKI-IEQLGTPMAEFMKKLQPTVRNYVENRPKY</Hsp_qseq>
      <Hsp_hseq>SFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNT-FCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNRNPKH</Hsp_hseq>
      <Hsp_midline>S +   D+YLV + M    L   +Q E     +R  + I +++  ++HLH   I++RDLKP NI++ ++  + + DFGL++        T +  T  Y APE++L   GYT+ VD WS+G ++ EM  G   F   ++   + KI   ++  P     ++ +  V+  +   PK+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.0998</Hsp_bit-score>
      <Hsp_score>183</Hsp_score>
      <Hsp_evalue>3.81927e-15</Hsp_evalue>
      <Hsp_query-from>341</Hsp_query-from>
      <Hsp_query-to>841</Hsp_query-to>
      <Hsp_hit-from>118</Hsp_hit-from>
      <Hsp_hit-to>279</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>175</Hsp_align-len>
      <Hsp_qseq>ELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMELDHERM-----SYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR---TAGNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIE</Hsp_qseq>
      <Hsp_hseq>ERRMLKLVEHPFLIRMWGTF------QDARNIFMVMDYIEGG--ELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTP-----DYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQ</Hsp_hseq>
      <Hsp_midline>E  ++K V H  +I ++  F      ++ +++++VM+ ++    ++  +    +R       +   +++  +++LH+  II+RDLKP NI++  +  +KI DFG A+   T   +   TP      Y APEVI    Y ++VD WS+G ++ EM+ G   F  T  +  + KI++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.8702</Hsp_bit-score>
      <Hsp_score>185</Hsp_score>
      <Hsp_evalue>4.64766e-15</Hsp_evalue>
      <Hsp_query-from>116</Hsp_query-from>
      <Hsp_query-to>838</Hsp_query-to>
      <Hsp_hit-from>129</Hsp_hit-from>
      <Hsp_hit-to>392</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>57</Hsp_gaps>
      <Hsp_align-len>281</Hsp_align-len>
      <Hsp_qseq>VLKRYQNLKPIGSGAQGIVC*WITMAALWRDPASSSSQLGCIDCA-AYDIMQNRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMEL---MDANLCQVIQMELDHERMSYLIYQ--------MLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGL---------------------ARTAGNSFMMTPYV------VTRYYRAPEVIL-GMGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKII</Hsp_qseq>
      <Hsp_hseq>VLNTYEIIKELGHGQHGKV-------KLARDILSK--QLVAIKIVDRHEKKQRKFFTFIKSSKISEND----KIKREIAIMKKCHHKHVVQLIEVLDDLKS----RKIYLVLEYCSRGEVKWCPPDCMESDAKGPSLLSFQETREILRGVVLGLEYLHYQGIIHRDIKPANLLISGDGTVKISDFGVSLAASSTNSSDSSESLDELELAKTVGTPAFFAPEMCLGEDAFTRYNLTKENLFRGSCISFMIDIWAVGVTLYCLLFGMLPFFSDFELKLFEKIV</Hsp_hseq>
      <Hsp_midline>VL  Y+ +K +G G  G V        L RD  S   QL  I     ++  Q +     K S+  +N     +  RE+ +MK  +HK+++ L  V    KS    + +YLV+E     +   C    ME D +  S L +Q        ++ G+++LH  GIIHRD+KP+N+++  D T+KI DFG+                     A+T G      P +       TRY    E +  G   +  +DIW+VG  +  ++ G + F     +  + KI+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.485</Hsp_bit-score>
      <Hsp_score>184</Hsp_score>
      <Hsp_evalue>6.33714e-15</Hsp_evalue>
      <Hsp_query-from>269</Hsp_query-from>
      <Hsp_query-to>841</Hsp_query-to>
      <Hsp_hit-from>519</Hsp_hit-from>
      <Hsp_hit-to>731</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>219</Hsp_align-len>
      <Hsp_qseq>NRNVAIKKLSR-PFQNQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMEL-MDANLCQVIQMELD----HERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNS----------------------FMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIE</Hsp_qseq>
      <Hsp_hseq>NRVYALKVLSKDEMIKRNKIKRVLTEQEILATSNHPFIVTLYHSFQSEDYL------YLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILK</Hsp_hseq>
      <Hsp_midline>NR  A+K LS+     +   KR   E  ++   NH  I+ L++ F  +  L      YL ME  M     + +Q         +   +   ++   +++LH  G I+RDLKP NI++     + + DF L+  A +S                      F    +V T  Y APEVI G G+T  VD W++G ++ EM+ G   F G +  + +  I++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.7146</Hsp_bit-score>
      <Hsp_score>182</Hsp_score>
      <Hsp_evalue>7.82606e-15</Hsp_evalue>
      <Hsp_query-from>251</Hsp_query-from>
      <Hsp_query-to>781</Hsp_query-to>
      <Hsp_hit-from>72</Hsp_hit-from>
      <Hsp_hit-to>246</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>181</Hsp_align-len>
      <Hsp_qseq>AYDIMQNRNVAIKKLSRPFQNQTHAK-RAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVI--QMELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYT-ENVDIWSVGCIMGEMI</Hsp_qseq>
      <Hsp_hseq>AYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVI---KSKDE---IIMVIEYAGNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVML</Hsp_hseq>
      <Hsp_midline>AY     + VA+K +++    ++  + R  RE+  ++ + H +II L++V    KS +E   + +V+E     L   I  + ++  +       Q++  +++ H   I+HRDLKP N+++     +KI DFGL+    +   +     +  Y APEVI G  Y    VD+WS G I+  M+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.559</Hsp_bit-score>
      <Hsp_score>179</Hsp_score>
      <Hsp_evalue>1.31304e-14</Hsp_evalue>
      <Hsp_query-from>341</Hsp_query-from>
      <Hsp_query-to>838</Hsp_query-to>
      <Hsp_hit-from>135</Hsp_hit-from>
      <Hsp_hit-to>295</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>171</Hsp_align-len>
      <Hsp_qseq>ELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMELDHERM-----SYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKII</Hsp_qseq>
      <Hsp_hseq>ERLMLSIVTHPFIIRMWGTF------QDAQQIFMIMDYIEGG--ELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPD--VTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKIL</Hsp_hseq>
      <Hsp_midline>E +++  V H  II ++  F      ++ Q ++++M+ ++    ++  +    +R       +   ++   +++LHS  II+RDLKP NI++  +  +KI DFG A+   +  +      T  Y APEV+    Y +++D WS G ++ EM+ G   F  ++ +  + KI+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.7886</Hsp_bit-score>
      <Hsp_score>177</Hsp_score>
      <Hsp_evalue>1.64433e-14</Hsp_evalue>
      <Hsp_query-from>326</Hsp_query-from>
      <Hsp_query-to>799</Hsp_query-to>
      <Hsp_hit-from>147</Hsp_hit-from>
      <Hsp_hit-to>301</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>161</Hsp_align-len>
      <Hsp_qseq>KRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVME-LMDANLCQVIQME--LDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLF</Hsp_qseq>
      <Hsp_hseq>KQFRREVEIQTSLNHPNLTKSYGYFHDEKR------VYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPPF</Hsp_hseq>
      <Hsp_midline>K+  RE+ +   +NH N+   +  F  +K       VYL+ME L++  + +++++    +    S  IYQ+   + ++H   IIHRD+KP NI++  +  +K+ DFG +              T  Y +PE++    Y   +D W++G +  E++ GA  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.7886</Hsp_bit-score>
      <Hsp_score>177</Hsp_score>
      <Hsp_evalue>2.91401e-14</Hsp_evalue>
      <Hsp_query-from>251</Hsp_query-from>
      <Hsp_query-to>799</Hsp_query-to>
      <Hsp_hit-from>54</Hsp_hit-from>
      <Hsp_hit-to>239</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>189</Hsp_align-len>
      <Hsp_qseq>AYDIMQNRNVAIKKLSRPF--QNQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNI--VVKSDCT-LKILDFGLA-RTAGNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLF</Hsp_qseq>
      <Hsp_hseq>AKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVR---ILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAF</Hsp_hseq>
      <Hsp_midline>A +     +VA+K L +     N+   +  Y EL +++ ++H NI+   + F  +        +    EL D  L +    E D  R   ++ ++L  +K++HS  I+HRDLKP N+  + KSD + L + DFG+A R   +  ++     +  Y APEV+   G+ +  DIWS+G I   ++ G   F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YNL183C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:293137:295509:-1 gene:YNL183C transcript:YNL183C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NPR1 description:Protein kinase; stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p; negatively regulates Ldb19p-mediated endocytosis through phosphorylation of Ldb19p, which prevents its association with the plasma membrane; Npr1p activity is negatively regulated via phosphorylation by the TOR complex; NPR1 has a paralog, PRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005127]</Hit_def>
  <Hit_accession>YNL183C</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>3.16845e-14</Hsp_evalue>
      <Hsp_query-from>251</Hsp_query-from>
      <Hsp_query-to>781</Hsp_query-to>
      <Hsp_hit-from>455</Hsp_hit-from>
      <Hsp_hit-to>635</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>187</Hsp_align-len>
      <Hsp_qseq>AYDIMQNRNVAIKKLSRPFQNQT---HAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVI-QMELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLART-----AGNSFMMTPYVVTRYYRAPEVILGMGYTEN-VDIWSVGCIMGEMI</Hsp_qseq>
      <Hsp_hseq>AQRISDNKIFAVKEFRTKFENESKRDYVKKITSEYCIGTTLNHPNIIETIEI------VYENDRILQVMEYCEYDLFAIVMSNKMSYEEICCCFKQILTGVQYLHSIGLAHRDLKLDNCVINEKGIVKLIDFGAAVVFSYPFSKNLVEASGIVGSDPYLAPEVCIFAKYDPRPVDIWSSAIIFACMI</Hsp_hseq>
      <Hsp_midline>A  I  N+  A+K+    F+N++   + K+   E  +   +NH NII    +      + E   +  VME  + +L  ++   ++ +E +     Q+L G+++LHS G+ HRDLK  N V+     +K++DFG A       + N    +  V +  Y APEV +   Y    VDIWS   I   MI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>4.40884e-14</Hsp_evalue>
      <Hsp_query-from>341</Hsp_query-from>
      <Hsp_query-to>838</Hsp_query-to>
      <Hsp_hit-from>136</Hsp_hit-from>
      <Hsp_hit-to>296</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>171</Hsp_align-len>
      <Hsp_qseq>ELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMELDHERM-----SYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKII</Hsp_qseq>
      <Hsp_hseq>ERRMLSIVSHPFIIRMWGTF------QDSQQVFMVMDYIEGG--ELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPD--VTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENIL</Hsp_hseq>
      <Hsp_midline>E  ++  V+H  II ++  F      ++ Q V++VM+ ++    ++  +    +R       +   ++   +++LHS  II+RDLKP NI++  +  +KI DFG A+   +  +      T  Y APEV+    Y ++VD WS G ++ EM+ G   F  ++ +  +  I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>6.6901e-14</Hsp_evalue>
      <Hsp_query-from>341</Hsp_query-from>
      <Hsp_query-to>841</Hsp_query-to>
      <Hsp_hit-from>174</Hsp_hit-from>
      <Hsp_hit-to>351</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>185</Hsp_align-len>
      <Hsp_qseq>ELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELM-DANLCQVIQM--ELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR----TAGNSFMMTPY----------VVTRYYRAPEVILGMGYTEN-VDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIE</Hsp_qseq>
      <Hsp_hseq>KLALQKLNGTKGIFKLFFTFQDEASL------YFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPE-LLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMK</Hsp_hseq>
      <Hsp_midline>+L L K    K I  LF  F  + SL      Y ++E     +   +I+    L+     Y   Q++  +  LH+ GIIHRD+KP NI++  +  +K+ DFG A+       N+    PY          V T  Y +PE +L   YT++  DIW+ GCI+ +M+ G   F   +    + K+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>1.297e-13</Hsp_evalue>
      <Hsp_query-from>269</Hsp_query-from>
      <Hsp_query-to>838</Hsp_query-to>
      <Hsp_hit-from>847</Hsp_hit-from>
      <Hsp_hit-to>1037</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>199</Hsp_align-len>
      <Hsp_qseq>NRNVAIKKLSRPFQNQTH---AKRAYRELVLMKC-VNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDAN--LCQVIQMELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTA---GNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKII</Hsp_qseq>
      <Hsp_hseq>DRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENR------IYFAMEFIGGGDLMWHVQNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNR--TSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAIL</Hsp_hseq>
      <Hsp_midline>+R  AIK L +    Q H   + RA +++ L+     H  +  L+  F  +        +Y  ME +     +  V    L   R  +   ++L  +K+ H  G+I+RDLK  NI++  +  +KI D+GL +     GN    + +  T  + APE++    YT+ VD W+ G ++ +M+     F G D  + +N I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>1.57209e-13</Hsp_evalue>
      <Hsp_query-from>341</Hsp_query-from>
      <Hsp_query-to>817</Hsp_query-to>
      <Hsp_hit-from>1149</Hsp_hit-from>
      <Hsp_hit-to>1310</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>170</Hsp_align-len>
      <Hsp_qseq>ELVLMKCVN---HKNIICLFNVFTPQKSLEEFQDVYLVMELMDA-----NLCQVIQMELD-HERMSYLIY-QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYT-ENVDIWSVGCIMGEMIRGAVLFPGTDHI</Hsp_qseq>
      <Hsp_hseq>EIQIMATLNKKPHENILRLLDFF-------EDDDYYYIETPVHGETGCIDLFDLIEFKTNMTEFEAKLIFKQVVAGIKHLHDQGIVHRDIKDENVIVDSKGFVKIIDFGSAAYV-KSGPFDVFVGTIDYAAPEVLGGNPYEGQPQDIWAIGILLYTVVFKENPFYNIDEI</Hsp_hseq>
      <Hsp_midline>E+ +M  +N   H+NI+ L + F       E  D Y +   +       +L  +I+ + +  E  + LI+ Q++ GIKHLH  GI+HRD+K  N++V S   +KI+DFG A     S     +V T  Y APEV+ G  Y  +  DIW++G ++  ++     F   D I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>1.97444e-13</Hsp_evalue>
      <Hsp_query-from>326</Hsp_query-from>
      <Hsp_query-to>787</Hsp_query-to>
      <Hsp_hit-from>177</Hsp_hit-from>
      <Hsp_hit-to>352</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>182</Hsp_align-len>
      <Hsp_qseq>KRAYRELVLMKCVNHKNIICL-FNVFTPQKSLEEFQDVYLVMELMDAN--LCQVIQMELDHERMS-YLIYQMLCGIKHLHSAGIIHRDLKPSNIVV-------------KSD-----------CTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRG</Hsp_qseq>
      <Hsp_hseq>KKVLNEVAIHKLVSKNNPHCTKFIAF--QESANYY---YLVTELVTGGEIFDRIVQLTCFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLRNNTAKTP-CGTIEYVASEVFTSKRYSMKVDMWSIGCVLFTLLCG</Hsp_hseq>
      <Hsp_midline>K+   E+ + K V+  N  C  F  F  Q+S   +   YLV EL+       +++Q+    E ++ ++I Q+   IKH+H  GI+HRD+KP N++              K D             +K++DFGLA+   N+   TP   T  Y A EV     Y+  VD+WS+GC++  ++ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>2.47804e-13</Hsp_evalue>
      <Hsp_query-from>350</Hsp_query-from>
      <Hsp_query-to>838</Hsp_query-to>
      <Hsp_hit-from>66</Hsp_hit-from>
      <Hsp_hit-to>243</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>184</Hsp_align-len>
      <Hsp_qseq>LMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDAN--LCQVIQMELDHERMS-YLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLART-----AGNSFMM-------------TPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKII</Hsp_qseq>
      <Hsp_hseq>LLAQKHHAGIIKLYYTF------HDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPFRGENELKTFEKIV</Hsp_hseq>
      <Hsp_midline>L+   +H  II L+  F       + +++Y V++       L  + +M   ++  + +   Q++  ++ +HS GIIHRDLKP N+++  D  L I DFG A T     +G+S                  +V T  Y +PE++L        DIW++GC++ + ++G   F G + +  + KI+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>2.90727e-13</Hsp_evalue>
      <Hsp_query-from>341</Hsp_query-from>
      <Hsp_query-to>826</Hsp_query-to>
      <Hsp_hit-from>1083</Hsp_hit-from>
      <Hsp_hit-to>1259</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>189</Hsp_align-len>
      <Hsp_qseq>ELVLMKCVNHKNIICLFNVFTPQKSLEEFQD-VYLVMELMDANLCQVIQMELDHERMS------YLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMT-----------------PYVVTRYYRAPEVILGMGYTENV---DIWSVGCIMGEMIRGAVLFPGTDHIDQW</Hsp_qseq>
      <Hsp_hseq>EMTVLEMLNHPNIVQYYGV-------EVHRDKVNIFMEYCEGGSLASL---LDHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRR--PWSNLDNEW</Hsp_hseq>
      <Hsp_midline>E+ +++ +NH NI+  + V       E  +D V + ME  +      +   LDH R+          +++L G+ +LH +G++HRD+KP NI++  +  +K +DFG ART   S   T                   + T  Y APE I G      +   D+W++GC++ EM  G    P ++  ++W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>3.45318e-13</Hsp_evalue>
      <Hsp_query-from>266</Hsp_query-from>
      <Hsp_query-to>835</Hsp_query-to>
      <Hsp_hit-from>47</Hsp_hit-from>
      <Hsp_hit-to>279</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>57</Hsp_gaps>
      <Hsp_align-len>240</Hsp_align-len>
      <Hsp_qseq>QNRNVAIKKLSRP-FQNQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVME---LMDANLCQVIQMEL-------------------DHERM------SYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCT---------------------LKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKI</Hsp_qseq>
      <Hsp_hseq>KSQHVAIKEVSRAKLKNKKLLENLEIEIAILKKIKHPHIVGLIDCERTS------TDFYLIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYL-QQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVVFEMCCGTPPFRASNHLELFKKI</Hsp_hseq>
      <Hsp_midline>++++VAIK++SR   +N+   +    E+ ++K + H +I+ L +            D YL+ME   L D       + EL                   +H  +      SYL  Q+   +K L S  ++HRD+KP N+++ +                        LKI DFG AR   N+ +      +  Y APE++    Y    D+WSVG ++ EM  G   F  ++H++ + KI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>3.96081e-13</Hsp_evalue>
      <Hsp_query-from>326</Hsp_query-from>
      <Hsp_query-to>799</Hsp_query-to>
      <Hsp_hit-from>168</Hsp_hit-from>
      <Hsp_hit-to>323</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>162</Hsp_align-len>
      <Hsp_qseq>KRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDAN--LCQVIQM-ELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYT-ENVDIWSVGCIMGEMIRGAVLF</Hsp_qseq>
      <Hsp_hseq>KRTVREASLGQILYHPHICRLFEMCTMSNHF------YMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPF</Hsp_hseq>
      <Hsp_midline>KR  RE  L + + H +I  LF + T           Y++ E +     L  +IQ   L           +   +++LH+  I+HRDLK  NI++ S   +KI+DFGL+        +  +  + Y+ APE++    YT   VDIWS G ++  ++ G V F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>4.42099e-13</Hsp_evalue>
      <Hsp_query-from>341</Hsp_query-from>
      <Hsp_query-to>823</Hsp_query-to>
      <Hsp_hit-from>894</Hsp_hit-from>
      <Hsp_hit-to>1070</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>185</Hsp_align-len>
      <Hsp_qseq>ELVLMKCVN---HKNIICLFNVFTPQKSLEEFQDVYLVM-----ELMDANLCQVIQMELDH-ERMSYLIY-QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYT-ENVDIWSVGCIM-------------GEMIRGAVLFPGTDHIDQ</Hsp_qseq>
      <Hsp_hseq>EIQIMATLNKNSQENILKLLDFF-------EDDDYYYIETPVHGETGSIDLFDVIEFKKDMVEHEAKLVFKQVVASIKHLHDQGIVHRDIKDENVIVDSHGFVKLIDFGSAAYI-KSGPFDVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLYTIIYKENPYYNIDEILEGELRFDKSEHVSE</Hsp_hseq>
      <Hsp_midline>E+ +M  +N    +NI+ L + F       E  D Y +      E    +L  VI+ + D  E  + L++ Q++  IKHLH  GI+HRD+K  N++V S   +K++DFG A     S     +V T  Y APEV+ G  Y  +  DIW++G ++              E++ G + F  ++H+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>6.08996e-13</Hsp_evalue>
      <Hsp_query-from>284</Hsp_query-from>
      <Hsp_query-to>802</Hsp_query-to>
      <Hsp_hit-from>481</Hsp_hit-from>
      <Hsp_hit-to>658</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>181</Hsp_align-len>
      <Hsp_qseq>IKKLSRPFQNQT-HAKRA---YRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAG----NSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLFP</Hsp_qseq>
      <Hsp_hseq>VGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLE-YVPGGSVSSMLNNYGPFE--ESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPFP</Hsp_hseq>
      <Hsp_midline>+  +S P  NQ  H K       E+ L+K ++H+NI+  +       +L  F + Y+    + + L      E     ++    Q+L G+ +LH   IIHRD+K +NI++     +KI DFG+++                 + ++ +PEV+     T   DIWS GC++ EM  G   FP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YOR267C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:822588:824867:-1 gene:YOR267C transcript:YOR267C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRK1 description:Protein kinase; implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005793]</Hit_def>
  <Hit_accession>YOR267C</Hit_accession>
  <Hit_len>759</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.5514</Hsp_bit-score>
      <Hsp_score>166</Hsp_score>
      <Hsp_evalue>8.02018e-13</Hsp_evalue>
      <Hsp_query-from>314</Hsp_query-from>
      <Hsp_query-to>781</Hsp_query-to>
      <Hsp_hit-from>256</Hsp_hit-from>
      <Hsp_hit-to>415</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>164</Hsp_align-len>
      <Hsp_qseq>QTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQM-ELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSF-----MMTPYVVTRYYRAPEVILGMGY--TENVDIWSVGCIMGEMI</Hsp_qseq>
      <Hsp_hseq>KEYAKKCTAEFCIGSTLHHPNVIETVDVFSDSKQ----NKYYEVMEYCPIDFFAVVMTGKMSRGEINCCLKQLTEGVKYLHSMGLAHRDLKLDNCVMTSQGILKLIDFGSAVVFRYPFEDGVTMAHGIVGSDPYLAPEVITSTKSYDPQCVDIWSIGIIYCCMV</Hsp_hseq>
      <Hsp_midline>+ +AK+   E  +   ++H N+I   +VF+  K        Y VME    +   V+   ++    ++  + Q+  G+K+LHS G+ HRDLK  N V+ S   LK++DFG A      F     M    V +  Y APEVI        + VDIWS+G I   M+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>1.30018e-12</Hsp_evalue>
      <Hsp_query-from>308</Hsp_query-from>
      <Hsp_query-to>802</Hsp_query-to>
      <Hsp_hit-from>220</Hsp_hit-from>
      <Hsp_hit-to>418</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>52</Hsp_gaps>
      <Hsp_align-len>208</Hsp_align-len>
      <Hsp_qseq>QNQTHAKRAYRELVLMKCVNHKNI------ICLFNVFTPQKSLEEFQDVYLVMELMDAN--LCQVIQMELDHERMS-YLIYQMLCGIKHLHSAGIIHRDLKPSNIVV--------------KSD--------------------CTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLFP</Hsp_qseq>
      <Hsp_hseq>KGKDSTKTSSRDQVLKEVALHKTVSAGCSQIVAFIDFQETDSY-----YYIIQELLTGGEIFGEIVRLTYFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKNTKTP-CGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTMLCG---FP</Hsp_hseq>
      <Hsp_midline>+ +   K + R+ VL +   HK +      I  F  F    S       Y++ EL+       +++++    E +S ++I Q+   +KH+HS G++HRD+KP N++               KSD                      +K+ DFGL++   +    TP   T  Y APEV+    Y+  VD+W +GC++  M+ G   FP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>1.97719e-12</Hsp_evalue>
      <Hsp_query-from>257</Hsp_query-from>
      <Hsp_query-to>799</Hsp_query-to>
      <Hsp_hit-from>173</Hsp_hit-from>
      <Hsp_hit-to>344</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>185</Hsp_align-len>
      <Hsp_qseq>DIMQNRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDAN--LCQVIQM-ELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYT-ENVDIWSVGCIMGEMIRGAVLF</Hsp_qseq>
      <Hsp_hseq>DVLERQKKLEKEISR-------DKRTIREASLGQILYHPHICRLFEMCTLSNHF------YMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPF</Hsp_hseq>
      <Hsp_midline>D+++ +    K++SR        KR  RE  L + + H +I  LF + T           Y++ E +     L  +IQ   +   +       +   + +LH+  I+HRDLK  NI++     +KI+DFGL+    +   +  +  + Y+ APE++    YT   VD+WS G ++  ++ G V F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>2.18708e-12</Hsp_evalue>
      <Hsp_query-from>272</Hsp_query-from>
      <Hsp_query-to>787</Hsp_query-to>
      <Hsp_hit-from>75</Hsp_hit-from>
      <Hsp_hit-to>248</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>181</Hsp_align-len>
      <Hsp_qseq>RNVAIKKLSRPFQNQTHAK--RAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELM-DANLCQVIQMELDHERMS--YLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLART--AGNSFMMTPYVVTRYYRAPEVILGMGYTE--NVDIWSVGCIMGEMIRG</Hsp_qseq>
      <Hsp_hseq>KQVAIKLIKRDSISNDYRKEVKIYREINALKHLSHPNIVKLEEV------LQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVNEFCSRNELMKT-SCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAG</Hsp_hseq>
      <Hsp_midline>+ VAIK + R   +  + K  + YRE+  +K ++H NI+ L  V      L+  + + +V+E        + IQ +   + M+   L  Q++ G+ ++HS G++HRDLK  N+++  +  L I DFG      + N  M T    +  Y APE+++     E    DIWS G I+  ++ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>2.5449e-12</Hsp_evalue>
      <Hsp_query-from>83</Hsp_query-from>
      <Hsp_query-to>787</Hsp_query-to>
      <Hsp_hit-from>1251</Hsp_hit-from>
      <Hsp_hit-to>1496</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>77</Hsp_gaps>
      <Hsp_align-len>279</Hsp_align-len>
      <Hsp_qseq>YSVEVGDSTFTVLKRYQNLKPIGSGAQGIVC*WITMAALWRDPASSSSQLGCIDCAAYDIMQNRNVAIKKLSRPFQNQTHAKRAY----RELVLMKCVNHKNIICLFNVFTPQKSLEEFQD-VYLVMELMDA-NLCQVIQMELDHERMSYLIY--QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFM---------------------------------MTPYVVTRYYRAPEVILG---MGYTENVDIWSVGCIMGEMIRG</Hsp_qseq>
      <Hsp_hseq>YLVSLASSISNVSMRWQKRNFIGGGTFGRVY------------------------SAVDLDNGEILAVKEIN--IQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGV-------EVHRDKVNIFMEYCEGGSLAALLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITG</Hsp_hseq>
      <Hsp_midline>Y V +  S   V  R+Q    IG G  G V                         +A D+     +A+K+++   Q+    ++ +     E+ +++ +NH NI+  + V       E  +D V + ME  +  +L  +++     + M   +Y  Q+L G+ +LH +GI+HRD+KP NI++  +  +K +DFG A+   N+                                   +   + T  Y APE I G    G     D+WS+GC++ EMI G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>71</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>3.02548e-12</Hsp_evalue>
      <Hsp_query-from>272</Hsp_query-from>
      <Hsp_query-to>898</Hsp_query-to>
      <Hsp_hit-from>75</Hsp_hit-from>
      <Hsp_hit-to>288</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>227</Hsp_align-len>
      <Hsp_qseq>RNVAIKKLSRPFQNQTHAK--RAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDAN-LCQVIQME--LDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSF-----MMTPYVVTRYYRAPEVILGMGYTE--NVDIWSVGCIMGEMIRGAVLF------PGTDHIDQWNKIIEQLGTPMAEFMKKLQPTVRN</Hsp_qseq>
      <Hsp_hseq>KQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEV------LQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFV----NEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARLYKYITQ--TPL-KFPEYITPIPRD</Hsp_hseq>
      <Hsp_midline>+ VAIK + R    +   K  + YRE+  +K + H NII L  V      L+  + + +V+E +      + IQ +  L       L  Q++ G+ ++H  G++HRDLK  N+++     L I DFG      N F     +M     +  Y APE+++     E    D+WS G I+  M+ G + +      P  D I +  K I Q  TP+ +F + + P  R+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>72</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>4.75527e-12</Hsp_evalue>
      <Hsp_query-from>347</Hsp_query-from>
      <Hsp_query-to>844</Hsp_query-to>
      <Hsp_hit-from>212</Hsp_hit-from>
      <Hsp_hit-to>436</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>73</Hsp_gaps>
      <Hsp_align-len>232</Hsp_align-len>
      <Hsp_qseq>VLMKCVNHKNIICLFNVFTPQKS---------LEEFQDVYLVMELMDAN-----LCQVIQMELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTA----------------------------------------------GNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLFPGT------DHIDQWNKIIEQ</Hsp_qseq>
      <Hsp_hseq>LLFKLNETKHVLTERDILTTTRSEWLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINTRCLKSGHAR--FYISEMFCAVNALHDLGYTHRDLKPENFLIDAKGHIKLTDFGLAAGTISNERIESMKIRLEKIKDLEFPAFTEKSIEDRRKMYNQLREKEINYANSMVGSP-----DYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYDNLRRWKQTLRR</Hsp_hseq>
      <Hsp_midline>+L K    K+++   ++ T  +S          ++ Q +YL ME +        L     ++  H R  + I +M C +  LH  G  HRDLKP N ++ +   +K+ DFGLA                                                  NS + +P      Y A EV+ G  Y   VD WS+GC++ E + G   F G+      D++ +W + + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>73</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>5.50129e-12</Hsp_evalue>
      <Hsp_query-from>488</Hsp_query-from>
      <Hsp_query-to>787</Hsp_query-to>
      <Hsp_hit-from>115</Hsp_hit-from>
      <Hsp_hit-to>216</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>102</Hsp_align-len>
      <Hsp_qseq>ELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVV-TRYYRAPEVIL-GMGYTENVDIWSVGCIMGEMIRG</Hsp_qseq>
      <Hsp_hseq>KIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATG</Hsp_hseq>
      <Hsp_midline>++D + +  ++ ++L  +K +H   +IHRD+K +N+++ ++  +K+ DFG+A     + +    +  T Y+ APEVI+ G+ Y   VDIWS+G    E+  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>74</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>5.54588e-12</Hsp_evalue>
      <Hsp_query-from>326</Hsp_query-from>
      <Hsp_query-to>787</Hsp_query-to>
      <Hsp_hit-from>60</Hsp_hit-from>
      <Hsp_hit-to>218</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>165</Hsp_align-len>
      <Hsp_qseq>KRAYRELVLM-KCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDA-NLCQVIQMEL--DHERMSYLIYQMLCGIKHLH-SAGIIHRDLKPSNIVVKSDCTLKILDFGLA----RTAGNSFMMTPYVVTRYYRAPEVILGMG--YTENVDIWSVGCIMGEMIRG</Hsp_qseq>
      <Hsp_hseq>KDITKEVVLQSKCSKHPNVLRLIDCNVSKEYM------WIILEMADGGDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTG</Hsp_hseq>
      <Hsp_midline>K   +E+VL  KC  H N++ L +    ++ +      ++++E+ D  +L   I+ ++  D +   +   Q++  I +LH   G+ HRD+KP NI++  +  LK+ DFGLA    R  G   +      +  Y APEV+      Y +  DIWS+G ++  ++ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>75</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>7.60799e-12</Hsp_evalue>
      <Hsp_query-from>347</Hsp_query-from>
      <Hsp_query-to>934</Hsp_query-to>
      <Hsp_hit-from>409</Hsp_hit-from>
      <Hsp_hit-to>618</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>222</Hsp_align-len>
      <Hsp_qseq>VLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQME------LDHERMSYLIYQMLCGIKHLHSA-GIIHRDLKPSNIVVKSD-CTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMG-----YTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQL-----GTPMAEFMKKLQPTVRNYV--------ENRPKYAGYS</Hsp_qseq>
      <Hsp_hseq>VLHKC-NSPYIVDFYGAFFIEGA------VYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSANQGTVKLCDFGVSGNLVASLAKT-NIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYP----PETYDNIFSQLSAIVDGPPPRLPSDKFSSDAQDFVSLCLQKIPERRPTYAALT</Hsp_hseq>
      <Hsp_midline>VL KC N   I+  +  F  + +      VY+ ME MD      I  E      +D  +++++   ++ G+K L     IIHRD+KP+NI+  ++  T+K+ DFG++     S   T  +  + Y APE I  +      YT   DIWS+G  + EM  G   +P     + ++ I  QL     G P      K     +++V        E RP YA  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>76</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>1.85519e-11</Hsp_evalue>
      <Hsp_query-from>281</Hsp_query-from>
      <Hsp_query-to>826</Hsp_query-to>
      <Hsp_hit-from>351</Hsp_hit-from>
      <Hsp_hit-to>538</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>196</Hsp_align-len>
      <Hsp_qseq>AIKKLSRPFQN--QTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLART-----------AGNSFMMTPYVVTRYYRAPEVILGMGYTEN-VDIWSVGCIMGEMIRGAVLFPGTDHIDQW</Hsp_qseq>
      <Hsp_hseq>AVKEFKRRTSESAEKYSKRLTSEFCISSSLHHTNIVTTLDLF--QDAKGEYCEVMEYCAGGDLFTLVVAAGKLEYMEADCFFKQLIRGVVYMHEMGVCHRDLKPENLLLTHDGVLKITDFGNSECFKMAWEKNIHLSGGVCGSSPYI------APEEYIKEEFDPRPVDIWACGVIYMAMRTGRQLWSSAEKDDPF</Hsp_hseq>
      <Hsp_midline>A+K+  R      + ++KR   E  +   ++H NI+   ++F  Q +  E+ +V       D     V   +L++        Q++ G+ ++H  G+ HRDLKP N+++  D  LKI DFG +             +G     +PY+      APE  +   +    VDIW+ G I   M  G  L+   +  D +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>77</Hit_num>
  <Hit_id>YDL025C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:405344:407206:-1 gene:YDL025C transcript:YDL025C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RTK1 description:Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002183]</Hit_def>
  <Hit_accession>YDL025C</Hit_accession>
  <Hit_len>620</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>2.54302e-11</Hsp_evalue>
      <Hsp_query-from>308</Hsp_query-from>
      <Hsp_query-to>781</Hsp_query-to>
      <Hsp_hit-from>346</Hsp_hit-from>
      <Hsp_hit-to>504</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>170</Hsp_align-len>
      <Hsp_qseq>QNQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLIYQMLC-GIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPY----------VVTRYYRAPEVILGMGYTENV-DIWSVGCIMGEMI</Hsp_qseq>
      <Hsp_hseq>QLANYSKKVTTEFCIGSTLHHENIVETLDMLT------EGDTYLLVMEYAPYDFFNLVMSNLMTQDEVNCYFKQLCHGVNYLHSMGLAHRDLKLDNCVVTKDGILKLIDFGSA-----VVFQYPYEDTIVKSHGIVGSDPYLAPELLKQTSYDPRVADVWSIAIIFYCMV</Hsp_hseq>
      <Hsp_midline>Q   ++K+   E  +   ++H+NI+   ++ T      E     LVME    +   ++   L  +      ++ LC G+ +LHS G+ HRDLK  N VV  D  LK++DFG A          PY          V +  Y APE++    Y   V D+WS+  I   M+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>78</Hit_num>
  <Hit_id>YPR111W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:747306:749000:1 gene:YPR111W transcript:YPR111W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF20 description:Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006315]</Hit_def>
  <Hit_accession>YPR111W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>3.41933e-11</Hsp_evalue>
      <Hsp_query-from>410</Hsp_query-from>
      <Hsp_query-to>853</Hsp_query-to>
      <Hsp_hit-from>231</Hsp_hit-from>
      <Hsp_hit-to>431</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>57</Hsp_gaps>
      <Hsp_align-len>203</Hsp_align-len>
      <Hsp_qseq>KSLEEFQD---VYLVMELMDAN-----LCQVIQMELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-TAGNSFMMT-------------PYVVTRY---------------------------YRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLFPGT------DHIDQWNKIIEQLGT</Hsp_qseq>
      <Hsp_hseq>KLLYAFQDPESLYLAMEFVPGGDFRTLLINTRILKSGHAR--FYISEMFCAVNALHELGYTHRDLKPENFLIDATGHIKLTDFGLAAGTVSNERIESMKIRLEEVKNLEFPAFTERSIEDRRKIYHNMRKTEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYENLRYWKKTLRRPRT</Hsp_hseq>
      <Hsp_midline>K L  FQD   +YL ME +        L     ++  H R  + I +M C +  LH  G  HRDLKP N ++ +   +K+ DFGLA  T  N  + +             P    R                            Y A EV+ G  Y   VD WS+GC++ E + G   F G+      +++  W K + +  T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>79</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>4.33263e-11</Hsp_evalue>
      <Hsp_query-from>335</Hsp_query-from>
      <Hsp_query-to>769</Hsp_query-to>
      <Hsp_hit-from>133</Hsp_hit-from>
      <Hsp_hit-to>279</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>159</Hsp_align-len>
      <Hsp_qseq>YRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMEL-MDANLCQVIQMEL---DHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKS-DCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVI-LGMGYTE--------NVDIWSVGCIM</Hsp_qseq>
      <Hsp_hseq>YEVDIQTKIGRHQNIAALLDFF----------DSYIIMEYCSGGDLYEAIKADAVPKKTKSITHIITQIMDAIEYVHNKGIYHRDIKPENILISGIDWTIKLTDWGLATTDKTS--MDRNVGSERYMSPELFDSNLDIKERKEPYDCAKVDLWAMGIVF</Hsp_hseq>
      <Hsp_midline>Y   +  K   H+NI  L + F          D Y++ME     +L + I+ +      + ++++I Q++  I+++H+ GI HRD+KP NI++   D T+K+ D+GLA T   S  M   V +  Y +PE+    +   E         VD+W++G + </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>80</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>6.53345e-11</Hsp_evalue>
      <Hsp_query-from>251</Hsp_query-from>
      <Hsp_query-to>799</Hsp_query-to>
      <Hsp_hit-from>19</Hsp_hit-from>
      <Hsp_hit-to>222</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>213</Hsp_align-len>
      <Hsp_qseq>AYDIMQNRNVAIKKLSRPFQNQTHAKRAYREL-VLMKCVNHKNIICLFNVFTPQKS----LE--EFQDVYLVMELMDANLC----QVIQMELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTA--GNSFMMTPYVVTRYYRAPEVILG-----------------MGYTENVDIWSVGCIMGEMIRGAVLF</Hsp_qseq>
      <Hsp_hseq>AWSTTHNRYVALKITPKYKTSEANMKNEYDVMKILSSCNPHPNICSMLDFYTDDSYYIMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQID-----MQKIIKQLCSAISFAHSLGIAHRDIKPENILLTINGDIKLADWGHAIQSPKSNDFQ----IGTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFGDCLF</Hsp_hseq>
      <Hsp_midline>A+    NR VA+K   +   ++ + K  Y  + +L  C  H NI  + + +T        LE  E  D+Y  +++  +        +IQ++     M  +I Q+   I   HS GI HRD+KP NI++  +  +K+ D+G A  +   N F     + T  YRAPE   G                 +  T   D WS+G  +  ++ G  LF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>81</Hit_num>
  <Hit_id>YFL029C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:78055:79161:-1 gene:YFL029C transcript:YFL029C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CAK1 description:Cyclin-dependent kinase-activating kinase; required for passage through the cell cycle; phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases [Source:SGD;Acc:S000001865]</Hit_def>
  <Hit_accession>YFL029C</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>1.4676e-10</Hsp_evalue>
      <Hsp_query-from>488</Hsp_query-from>
      <Hsp_query-to>775</Hsp_query-to>
      <Hsp_hit-from>126</Hsp_hit-from>
      <Hsp_hit-to>236</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>111</Hsp_align-len>
      <Hsp_qseq>ELDHERMSYLIY-QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCT-----LKILDFGLARTAGNSFMMTPY--------VVTRYYRAPEVILGMG-YTENVDIWSVGCIMGE</Hsp_qseq>
      <Hsp_hseq>QLDVNRYSLSFFRQMVEGIAFLHENKIIHRDIKPQNIMLTNNTSTVSPKLYIIDFGISYDMANNSQTSAEPMDSKVTDISTGIYKAPEVLFGVKCYDGGVDVWSLLIIISQ</Hsp_hseq>
      <Hsp_midline>+LD  R S   + QM+ GI  LH   IIHRD+KP NI++ ++ +     L I+DFG++    N+   +          + T  Y+APEV+ G+  Y   VD+WS+  I+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>82</Hit_num>
  <Hit_id>YDL214C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:74446:76545:-1 gene:YDL214C transcript:YDL214C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR2 description:Serine/threonine protein kinase; inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance; PRR2 has a paralog, NPR1, that arose from the whole genome duplication [Source:SGD;Acc:S000002373]</Hit_def>
  <Hit_accession>YDL214C</Hit_accession>
  <Hit_len>699</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>3.47215e-10</Hsp_evalue>
      <Hsp_query-from>284</Hsp_query-from>
      <Hsp_query-to>781</Hsp_query-to>
      <Hsp_hit-from>375</Hsp_hit-from>
      <Hsp_hit-to>558</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>184</Hsp_align-len>
      <Hsp_qseq>IKKLSRPFQNQTHAKRAYRELVLMKCVNH--KNIICLFNVFTPQKS---------LEEFQDVYLVMELMDANLCQVIQME-LDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLART-----AGNSFMMTPYVVTRYYRAPEVILGMGYT-ENVDIWSVGCIMGEMI</Hsp_qseq>
      <Hsp_hseq>VKLVQRVLDNKVFALKEYRSKKKRESERKYIKNIISEYCIASTLKNPNICETLEILYEKGKIFQILEYCEYDLFSLVMSEKMHYEEICCLFKQLINGVKYLHDIGLSHRDLKLDNCVVTRRGILKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFYFNEYDPRALDVWSVGIIFFCMI</Hsp_hseq>
      <Hsp_midline>+K + R   N+  A + YR     +      KNII  + + +  K+         L E   ++ ++E  + +L  ++  E + +E +  L  Q++ G+K+LH  G+ HRDLK  N VV     LK++DFG +       +         V +  Y +PEV     Y    +D+WSVG I   MI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>83</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.5362</Hsp_bit-score>
      <Hsp_score>140</Hsp_score>
      <Hsp_evalue>1.5118e-09</Hsp_evalue>
      <Hsp_query-from>515</Hsp_query-from>
      <Hsp_query-to>844</Hsp_query-to>
      <Hsp_hit-from>137</Hsp_hit-from>
      <Hsp_hit-to>247</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>111</Hsp_align-len>
      <Hsp_qseq>LIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYTE-NVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQ</Hsp_qseq>
      <Hsp_hseq>LFAQISGAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTRECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNE</Hsp_hseq>
      <Hsp_midline>L  Q+   + + HS   +HRDLK  NI++  +   K+ DFG  R       +     T  Y APE+I    Y    +DIWS+G I+  +I G + F   D      KI+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>84</Hit_num>
  <Hit_id>YAR018C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:170396:171703:-1 gene:YAR018C transcript:YAR018C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN3 description:Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol [Source:SGD;Acc:S000000071]</Hit_def>
  <Hit_accession>YAR018C</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>2.7568e-09</Hsp_evalue>
      <Hsp_query-from>563</Hsp_query-from>
      <Hsp_query-to>835</Hsp_query-to>
      <Hsp_hit-from>170</Hsp_hit-from>
      <Hsp_hit-to>300</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>131</Hsp_align-len>
      <Hsp_qseq>IIHRDLKPSNIVVKSD---------------------------------------CTLKILDFGLARTAGNSFMM-TPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKI</Hsp_qseq>
      <Hsp_hseq>VIHRDLKPGNIFLSYDDSDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLAKSLETSIQFATTYVGTPYYMSPEVLMDQPYSPLSDIWSLGCVIFEMCSLHPPFQAKNYLELQTKI</Hsp_hseq>
      <Hsp_midline>+IHRDLKP NI +  D                                         +K+ DFGLA++   S    T YV T YY +PEV++   Y+   DIWS+GC++ EM      F   ++++   KI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>85</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>2.88079e-09</Hsp_evalue>
      <Hsp_query-from>422</Hsp_query-from>
      <Hsp_query-to>835</Hsp_query-to>
      <Hsp_hit-from>518</Hsp_hit-from>
      <Hsp_hit-to>662</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>148</Hsp_align-len>
      <Hsp_qseq>EFQDVYLVMELM--DANLCQVIQME-------LDHERMSYLIYQMLCGIKHLH-SAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKI</Hsp_qseq>
      <Hsp_hseq>KFQNSYYIMTELCENGNLDGFLQEQVIAKKKRLEDWRIWKIIVELSLALRFIHDSCHIVHLDLKPANVMITFEGNLKLGDFGMATHLPLEDKSFENEGDREYIAPEIISDCTYDYKADIFSLGLMIVEIAANVVL---PDNGNAWHKL</Hsp_hseq>
      <Hsp_midline>+FQ+ Y +M  +  + NL   +Q +       L+  R+  +I ++   ++ +H S  I+H DLKP+N+++  +  LK+ DFG+A               R Y APE+I    Y    DI+S+G ++ E+    VL    D+ + W+K+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>86</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>5.40862e-09</Hsp_evalue>
      <Hsp_query-from>338</Hsp_query-from>
      <Hsp_query-to>799</Hsp_query-to>
      <Hsp_hit-from>258</Hsp_hit-from>
      <Hsp_hit-to>445</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>188</Hsp_align-len>
      <Hsp_qseq>RELVLMKCVNHKNIICLFNVFTPQ-------------KSLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLI----YQMLCGIKHLHSAGIIHRDLKPSNIVVKSD-------------CT---LKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYTENV-DIWSVGCIMGEMIRGAVLF</Hsp_qseq>
      <Hsp_hseq>RELQVLKSLNHPCIVKLLGINNPIFVTSKKPLCDLIIKTPRALPPCDMIMSYCPAGDLLAAVMARNGRLEAWLIQRIFTEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLCKKIENNEMCTARCGSEDYVSPEILMGVPYDGHLSDTWALGVILYSLFEDRLPF</Hsp_hseq>
      <Hsp_midline>REL ++K +NH  I+ L  +  P              K+        ++M    A       M  +    ++LI     +++  +K+LH   IIHRDLK  NI++K               C    +++ DFGL +   N+ M T    +  Y +PE+++G+ Y  ++ D W++G I+  +    + F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>87</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>1.08701e-08</Hsp_evalue>
      <Hsp_query-from>338</Hsp_query-from>
      <Hsp_query-to>805</Hsp_query-to>
      <Hsp_hit-from>210</Hsp_hit-from>
      <Hsp_hit-to>387</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>178</Hsp_align-len>
      <Hsp_qseq>RELVLMKCVNHKNIICLFNVFTPQKS-LEEFQDVYLVMELMDANLCQVIQMELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVV--KSDCTLKIL-DFGLARTA-GNSFMMTPYVVTRYYRAPEV-----------------ILGMGYTENVDIWSVGCIMGEMIRGAVLFPG</Hsp_qseq>
      <Hsp_hseq>KEARILLRLDHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGISPFYG</Hsp_hseq>
      <Hsp_midline>+E  ++  ++H NII +++ F  + + L  FQD+    +L            +       +++Q+L  + +LH   I+HRDLK  NI++     CT  +L DFG+A+    N   M   V T  Y APEV                 +   GY    D+WS+G I   M+ G   F G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>88</Hit_num>
  <Hit_id>YPL204W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:164276:165760:1 gene:YPL204W transcript:YPL204W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRR25 description:Conserved casein kinase; regulates diverse events including: vesicular traffic, DNA repair, the CVT pathway, monopolar attachment of sister kinetochores at meiosis I, and ribosomal subunit biogenesis; monopolin subunit; binds the RNAPII CTD; phosphorylates COPII coat subunits; interacts with Sit4p phosphatase; antagonizes calcineurin signaling, reducing nuclear accumulation of Crz1p; phosphorylates Dsn1p, the kinetochore receptor for monopolin; homolog of mammalian CK1delta [Source:SGD;Acc:S000006125]</Hit_def>
  <Hit_accession>YPL204W</Hit_accession>
  <Hit_len>494</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>3.0132e-08</Hsp_evalue>
      <Hsp_query-from>497</Hsp_query-from>
      <Hsp_query-to>844</Hsp_query-to>
      <Hsp_hit-from>97</Hsp_hit-from>
      <Hsp_hit-to>231</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>135</Hsp_align-len>
      <Hsp_qseq>HERMSY-----LIYQMLCGIKHLHSAGIIHRDLKPSNIVV---KSDCTLKILDFGLARTAG--NSFMMTPY------VVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLFPG---TDHIDQWNKIIEQ</Hsp_qseq>
      <Hsp_hseq>HRRFSFKTVIMLALQMFCRIQYIHGRSFIHRDIKPDNFLMGVGRRGSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLTGTARYASVNTHLGIEQSRRDDLESLGYVLIYFCKGSLPWQGLKATTKKQKYDRIMEK</Hsp_hseq>
      <Hsp_midline>H R S+     L  QM C I+++H    IHRD+KP N ++   +   T+ ++DFGL++     N+    PY        T  Y +    LG+  +   D+ S+G ++    +G++ + G   T    ++++I+E+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>89</Hit_num>
  <Hit_id>YFL033C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:69115:74427:-1 gene:YFL033C transcript:YFL033C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM15 description:Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase [Source:SGD;Acc:S000001861]</Hit_def>
  <Hit_accession>YFL033C</Hit_accession>
  <Hit_len>1770</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>6.74974e-08</Hsp_evalue>
      <Hsp_query-from>119</Hsp_query-from>
      <Hsp_query-to>652</Hsp_query-to>
      <Hsp_hit-from>791</Hsp_hit-from>
      <Hsp_hit-to>943</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>43</Hsp_gaps>
      <Hsp_align-len>187</Hsp_align-len>
      <Hsp_qseq>LKRYQNLKPIGSGAQGIVC*WITMAALWRDPASSSSQLGCIDCAAYDIMQNRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVME-LMDANLCQVIQMELDHERMSYL--------IYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTA</Hsp_qseq>
      <Hsp_hseq>IKDYDILKPISKGAYGSV--YLARKKL------------TGDYFAIKVLRKSDMIAK-------NQVTNVKSERAIMMVQS-DKPYVARLFASFQNKDNL------FLVMEYLPGGDLATLIKM------MGYLPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLIDNAGHVKLTDFGLSRAG</Hsp_hseq>
      <Hsp_midline>+K Y  LKPI  GA G V  ++    L              D  A  +++  ++  K       NQ    ++ R +++++  +   +  LF  F  + +L      +LVME L   +L  +I+M      M YL        + +++ G+  +H  GIIH DLKP N+++ +   +K+ DFGL+R  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>90</Hit_num>
  <Hit_id>YPL026C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:500675:502183:-1 gene:YPL026C transcript:YPL026C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKS1 description:Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway; SKS1 has a paralog, VHS1, that arose from the whole genome duplication [Source:SGD;Acc:S000005947]</Hit_def>
  <Hit_accession>YPL026C</Hit_accession>
  <Hit_len>502</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>6.9244e-08</Hsp_evalue>
      <Hsp_query-from>308</Hsp_query-from>
      <Hsp_query-to>769</Hsp_query-to>
      <Hsp_hit-from>98</Hsp_hit-from>
      <Hsp_hit-to>265</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>175</Hsp_align-len>
      <Hsp_qseq>QNQTHAKRAYRELVL-MKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVI---QMELDHERMSYLIYQMLC-GIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVIL--------GMGY--------TENVDIWSVGCIM</Hsp_qseq>
      <Hsp_hseq>ENELNRLPHYREIAFQLRVQSHGNIVKIHQV------LESSIATFIVMDYYDRDLFTSIVDDKHFVNHGILIKKVFLQLCSALDHCHRLGIYHCDIKPENVLLDRNDNAYLCDFGLS-TKSKYLAPNVCVGSSYYMAPERILYCLNTTTNGIHVDECCSSLPTDTGDIWSLGIIL</Hsp_hseq>
      <Hsp_midline>+N+ +    YRE+   ++  +H NI+ +  V      LE     ++VM+  D +L   I   +  ++H  +   ++  LC  + H H  GI H D+KP N+++  +    + DFGL+ T          V + YY APE IL        G+          T+  DIWS+G I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>91</Hit_num>
  <Hit_id>YKL198C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:68232:70220:-1 gene:YKL198C transcript:YKL198C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK1 description:Putative serine/threonine protein kinase; regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein; PTK1 has a paralog, PTK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001681]</Hit_def>
  <Hit_accession>YKL198C</Hit_accession>
  <Hit_len>662</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>7.18296e-08</Hsp_evalue>
      <Hsp_query-from>326</Hsp_query-from>
      <Hsp_query-to>643</Hsp_query-to>
      <Hsp_hit-from>241</Hsp_hit-from>
      <Hsp_hit-to>351</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>111</Hsp_align-len>
      <Hsp_qseq>KRAYRELVLMKCVNHK-NIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQ----MELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA</Hsp_qseq>
      <Hsp_hseq>KRCSKEFIIAKQLSHHVHITNTFLLVKVPTTVYTTRGWGFVMELGLRDLFAMIQKSGWRSVALAEKFCIFKQVACGVKFCHDQGIAHRDLKPENVLLSPDGVCKLTDFGIS</Hsp_hseq>
      <Hsp_midline>KR  +E ++ K ++H  +I   F +     ++   +    VMEL   +L  +IQ      +       +  Q+ CG+K  H  GI HRDLKP N+++  D   K+ DFG++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>92</Hit_num>
  <Hit_id>YKL168C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:131288:133462:-1 gene:YKL168C transcript:YKL168C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KKQ8 description:Putative serine/threonine protein kinase with unknown cellular role; KKQ8 has a paralog, HAL5, that arose from the whole genome duplication [Source:SGD;Acc:S000001651]</Hit_def>
  <Hit_accession>YKL168C</Hit_accession>
  <Hit_len>724</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>1.34085e-07</Hsp_evalue>
      <Hsp_query-from>515</Hsp_query-from>
      <Hsp_query-to>883</Hsp_query-to>
      <Hsp_hit-from>543</Hsp_hit-from>
      <Hsp_hit-to>663</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>130</Hsp_align-len>
      <Hsp_qseq>LIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPY-----VVTRYYRAPEVILGMGYTEN--VDIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIEQLGTPMAEFMKKLQ</Hsp_qseq>
      <Hsp_hseq>FMKQLLHGVKFMHDHGIAHCDLKPENILFYPHGLLKICDFGTSSVFQTAWERRVHAQKGIIGSEPYVAPEEFVDGEYYDPRLIDCWSCGVVYITMILGHYL---------WKVASREKDMSYDEFYKEMQ</Hsp_hseq>
      <Hsp_midline> + Q+L G+K +H  GI H DLKP NI+      LKI DFG +     ++    +     + +  Y APE  +   Y +   +D WS G +   MI G  L         W     +      EF K++Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>93</Hit_num>
  <Hit_id>YMR216C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:698811:701039:-1 gene:YMR216C transcript:YMR216C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKY1 description:SR protein kinase (SRPK); involved in regulating proteins involved in mRNA metabolism and cation homeostasis; similar to human SRPK1 [Source:SGD;Acc:S000004829]</Hit_def>
  <Hit_accession>YMR216C</Hit_accession>
  <Hit_len>742</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>1.37609e-07</Hsp_evalue>
      <Hsp_query-from>584</Hsp_query-from>
      <Hsp_query-to>1024</Hsp_query-to>
      <Hsp_hit-from>540</Hsp_hit-from>
      <Hsp_hit-to>679</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>153</Hsp_align-len>
      <Hsp_qseq>PSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGAVLF-PGTDHI-----DQWNKIIEQLGTPMAEFMKKLQPTVRNYVENRPKYAGYSFEKLFPDPPPKIYDKQLDEREHSIDEWKEL</Hsp_qseq>
      <Hsp_hseq>PENLI-----QIKIADLGNACWYDEHY--TNSIQTREYRSPEVLLGAPWGCGADIWSTACLIFELITGDFLFEPDEGHSYTKDDDHIAQIIELLGE-LPSYLLRNGKYTRTFFNSRGLLRNISKLKFWP-----LEDVLTEKYKFSKDEAKEI</Hsp_hseq>
      <Hsp_midline>P N++      +KI D G A      +  T  + TR YR+PEV+LG  +    DIWS  C++ E+I G  LF P   H      D   +IIE LG  +  ++ +     R +  +R      S  K +P     + D   ++ + S DE KE+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>94</Hit_num>
  <Hit_id>YJL165C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:106894:109461:-1 gene:YJL165C transcript:YJL165C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HAL5 description:Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters; HAL5 has a paralog, KKQ8, that arose from the whole genome duplication [Source:SGD;Acc:S000003701]</Hit_def>
  <Hit_accession>YJL165C</Hit_accession>
  <Hit_len>855</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>1.77061e-07</Hsp_evalue>
      <Hsp_query-from>515</Hsp_query-from>
      <Hsp_query-to>799</Hsp_query-to>
      <Hsp_hit-from>668</Hsp_hit-from>
      <Hsp_hit-to>769</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>102</Hsp_align-len>
      <Hsp_qseq>LIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSF-----MMTPYVVTRYYRAP-EVILGMGYTEN-VDIWSVGCIMGEMIRGAVLF</Hsp_qseq>
      <Hsp_hseq>FMKQLLNGVQYMHDHGIAHCDLKPENILFQPNGLLKICDFGTSSVFQTAWEKHVHFQSGAMGSEPYVAPEEFIRDAEYDPRLVDCWSCGIVYCTMVMGQYLW</Hsp_hseq>
      <Hsp_midline> + Q+L G++++H  GI H DLKP NI+ + +  LKI DFG +     ++       +  + +  Y AP E I    Y    VD WS G +   M+ G  L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>95</Hit_num>
  <Hit_id>YIL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:183937:186369:1 gene:YIL095W transcript:YIL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRK1 description:Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton and reduces endocytic ability of cell through the phosphorylation of the Pan1p-Sla1p-End3p protein complex; PRK1 has a paralog, ARK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001357]</Hit_def>
  <Hit_accession>YIL095W</Hit_accession>
  <Hit_len>810</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>3.03119e-07</Hsp_evalue>
      <Hsp_query-from>224</Hsp_query-from>
      <Hsp_query-to>769</Hsp_query-to>
      <Hsp_hit-from>34</Hsp_hit-from>
      <Hsp_hit-to>235</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>205</Hsp_align-len>
      <Hsp_qseq>SQLGCIDCAAYDIMQNRNVA-IKKLSRPFQNQTHAKRAYRELVLMKCV-NHKNIICLFNVFTPQKSLEEFQDVYLVMELMDAN-----LCQVIQMELDHERMSYLIYQMLCGIKHLHS--AGIIHRDLKPSNIVVKSDCTLKILDF----GLARTAGNSFMMTPYV-------VTRYYRAPEVI---LGMGYTENVDIWSVGCIM</Hsp_qseq>
      <Hsp_hseq>AQVYTAEISPPDPYSNANIACLKRVIVPHKQGLNTLRA--EVDAMKLLRNNKHVVSYIDSHAARSVNGIAYEVFVLMEFCERGGLIDFMNTRLQNRLQESEILEIMSQTVQGITAMHALQPPLIHRDIKIENVLISHDGLYKVCDFGSVSGVIRPPRNTQEFN-YVQHDILTNTTAQYRSPEMIDLYRGLPIDEKSDIWALGVFL</Hsp_hseq>
      <Hsp_midline>+Q+   + +  D   N N+A +K++  P +   +  RA  E+  MK + N+K+++   +    +       +V+++ME  +       +   +Q  L    +  ++ Q + GI  +H+    +IHRD+K  N+++  D   K+ DF    G+ R   N+     YV        T  YR+PE+I    G+   E  DIW++G  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>96</Hit_num>
  <Hit_id>YKL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:347214:349136:-1 gene:YKL048C transcript:YKL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ELM1 description:Serine/threonine protein kinase; regulates the orientation checkpoint, the morphogenesis checkpoint and the metabolic switch from fermentative to oxidative metabolism by phosphorylating the activation loop of Kin4p, Hsl1p and Snf4p respectively; cooperates with Hsl7p in recruiting Hsl1p to the septin ring, a prerequisite for subsequent recruitment, phosphorylation, and degradation of Swe1p; forms part of the bud neck ring; regulates cytokinesis [Source:SGD;Acc:S000001531]</Hit_def>
  <Hit_accession>YKL048C</Hit_accession>
  <Hit_len>640</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>3.26331e-07</Hsp_evalue>
      <Hsp_query-from>515</Hsp_query-from>
      <Hsp_query-to>841</Hsp_query-to>
      <Hsp_hit-from>239</Hsp_hit-from>
      <Hsp_hit-to>368</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>130</Hsp_align-len>
      <Hsp_qseq>LIYQMLCGIKHLHSAGIIHRDLKPSNIVV-KSDCTLKILDFGLARTAGNSF-------------MMTPYVVTRYYRAPEVI-LGMGYTENV------DIWSVGCIMGEMIRGAVLFPGTDHIDQWNKIIE</Hsp_qseq>
      <Hsp_hseq>ILEDMTKGLEYLHSQGCIHRDIKPSNILLDEEEKVAKLSDFGSCIFTPQSLPFSDANFEDCFQRELNKIVGTPAFIAPELCHLGNSKRDFVTDGFKLDIWSLGVTLYCLLYNELPFFGENEFETYHKIIE</Hsp_hseq>
      <Hsp_midline>++  M  G+++LHS G IHRD+KPSNI++ + +   K+ DFG       S               +   V T  + APE+  LG    + V      DIWS+G  +  ++   + F G +  + ++KIIE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>97</Hit_num>
  <Hit_id>YHR079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:258244:261591:-1 gene:YHR079C transcript:YHR079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IRE1 description:Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; role in homeostatic adaptation to ER stress; Kar2p binds inactive Ire1p and releases from it upon ER stress [Source:SGD;Acc:S000001121]</Hit_def>
  <Hit_accession>YHR079C</Hit_accession>
  <Hit_len>1115</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>3.51214e-07</Hsp_evalue>
      <Hsp_query-from>263</Hsp_query-from>
      <Hsp_query-to>715</Hsp_query-to>
      <Hsp_hit-from>694</Hsp_hit-from>
      <Hsp_hit-to>861</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>180</Hsp_align-len>
      <Hsp_qseq>MQNRNVAIKKLSRPFQNQTHAKRAYREL-VLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQ----------MELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDC-----------TLKIL--DFGLART--AGNSFMMTPY---VVTRYYRAPEVI</Hsp_qseq>
      <Hsp_hseq>FQGRPVAVKRMLIDF-----CDIALMEIKLLTESDDHPNVIRYYCSETTDRFL------YIALELCNLNLQDLVESKNVSDENLKLQKEYNPIS-LLRQIASGVAHLHSLKIIHRDLKPQNILVSTSSRFTADQQTGAENLRILISDFGLCKKLDSGQSSFRTNLNNPSGTSGWRAPELL</Hsp_hseq>
      <Hsp_midline> Q R VA+K++   F        A  E+ +L +  +H N+I  +   T  + L      Y+ +EL + NL  +++          ++ ++  +S L+ Q+  G+ HLHS  IIHRDLKP NI+V +              L+IL  DFGL +   +G S   T       T  +RAPE++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>98</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>7.55271e-07</Hsp_evalue>
      <Hsp_query-from>413</Hsp_query-from>
      <Hsp_query-to>643</Hsp_query-to>
      <Hsp_hit-from>418</Hsp_hit-from>
      <Hsp_hit-to>497</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>25</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>80</Hsp_align-len>
      <Hsp_qseq>SLEEFQDVYLVMELMDAN--LCQVIQMELDHERMS-YLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA</Hsp_qseq>
      <Hsp_hseq>SFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLS</Hsp_hseq>
      <Hsp_midline>S ++ Q +YL+ME +     +  +I+ +L  E ++ + + + +  I+ +H  G IHRD+KP NI++     +K+ DFGL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>99</Hit_num>
  <Hit_id>YJR059W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:545787:548243:1 gene:YJR059W transcript:YJR059W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK2 description:Serine/threonine protein kinase; involved in regulation of ion transport across plasma membrane; carboxyl terminus is essential for glucose-dependent Pma1p activation via phosphorylation of Pma1p-Ser899; enhances spermine uptake; PTK2 has a paralog, PTK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003820]</Hit_def>
  <Hit_accession>YJR059W</Hit_accession>
  <Hit_len>818</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>9.51385e-07</Hsp_evalue>
      <Hsp_query-from>281</Hsp_query-from>
      <Hsp_query-to>643</Hsp_query-to>
      <Hsp_hit-from>283</Hsp_hit-from>
      <Hsp_hit-to>410</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>128</Hsp_align-len>
      <Hsp_qseq>AIKKLSRPFQNQTHA--KRAYRELVLMKCVNHK-NIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQM----ELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA</Hsp_qseq>
      <Hsp_hseq>ALKKLNMIYHESPEKFYKRCSKEFIIAKHLSHNVHITNTFYLLKVPTTTYTTRGWGFIMELGVKDLFQLMERTGWKNVPFNEKYCLFKQVAQGIKFCHDNGIAHRDLKPENVLISKEGICKLTDFGIS</Hsp_hseq>
      <Hsp_midline>A+KKL+  +        KR  +E ++ K ++H  +I   F +     +    +    +MEL   +L Q+++      +       L  Q+  GIK  H  GI HRDLKP N+++  +   K+ DFG++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>100</Hit_num>
  <Hit_id>YBR059C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:356861:360187:-1 gene:YBR059C transcript:YBR059C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AKL1 description:Ser-Thr protein kinase; member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization [Source:SGD;Acc:S000000263]</Hit_def>
  <Hit_accession>YBR059C</Hit_accession>
  <Hit_len>1108</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.9802</Hsp_bit-score>
      <Hsp_score>110</Hsp_score>
      <Hsp_evalue>6.28228e-06</Hsp_evalue>
      <Hsp_query-from>380</Hsp_query-from>
      <Hsp_query-to>781</Hsp_query-to>
      <Hsp_hit-from>127</Hsp_hit-from>
      <Hsp_hit-to>262</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>149</Hsp_align-len>
      <Hsp_qseq>ICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLIYQMLCGIKHLH--SAGIIHRDLKPSNIVVKSDCTLKILDFG-------LARTAGNSFMMTPYV---VTRYYRAPEVI---LGMGYTENVDIWSVGCIMGEMI</Hsp_qseq>
      <Hsp_hseq>VLLLMELCPNKSLLDYMNQRLSTKLTEAEIVKIM-------------YDVALSISQMHYLPVSLIHRDIKIENVLVDAKNNFKLADFGSTSTCFPIVTTHQDIALLTQNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGVFLYKLL</Hsp_hseq>
      <Hsp_midline>+ L     P KSL ++ +  L  +L +A + +++             Y +   I  +H     +IHRD+K  N++V +    K+ DFG       +  T  +  ++T  +    T  YR+PE+I     +   E  DIW++G  + +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>93</Statistics_hsp-len>
      <Statistics_eff-space>864900392</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0043406-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.5|0.66|3|0|86</Iteration_query-def>
  <Iteration_query-len>261</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>58</Statistics_hsp-len>
      <Statistics_eff-space>73406743</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0028074-RA transcript Note:&quot;Similar to ANTXR1 Anthrax toxin receptor 1 (Homo sapiens)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.4|0.54|11|0|307</Iteration_query-def>
  <Iteration_query-len>924</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>89</Statistics_hsp-len>
      <Statistics_eff-space>509540073</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0005758-RA transcript Note:&quot;Similar to BMP3 Bone morphogenetic protein 3 (Bos taurus)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0|0.33|3|0|299</Iteration_query-def>
  <Iteration_query-len>900</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>89</Statistics_hsp-len>
      <Statistics_eff-space>490926737</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0005759-RA transcript Note:&quot;Similar to Aak1 AP2-associated protein kinase 1 (Rattus norvegicus)&quot; offset:0 AED:0.43 eAED:0.43 QI:0|0.85|0.75|1|0.14|0.37|8|107|323</Iteration_query-def>
  <Iteration_query-len>1079</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>620009156</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0043404-RA transcript Note:&quot;Similar to AAK1 AP2-associated protein kinase 1 (Bos taurus)&quot; offset:0 AED:0.52 eAED:0.52 QI:0|0.87|0.66|0.88|0.5|0.66|9|0|351</Iteration_query-def>
  <Iteration_query-len>1056</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YNL020C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:595623:597539:-1 gene:YNL020C transcript:YNL020C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ARK1 description:Serine/threonine protein kinase; involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis; ARK1 has a paralog, PRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004965]</Hit_def>
  <Hit_accession>YNL020C</Hit_accession>
  <Hit_len>638</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>216.468</Hsp_bit-score>
      <Hsp_score>550</Hsp_score>
      <Hsp_evalue>2.28512e-65</Hsp_evalue>
      <Hsp_query-from>100</Hsp_query-from>
      <Hsp_query-to>987</Hsp_query-to>
      <Hsp_hit-from>11</Hsp_hit-from>
      <Hsp_hit-to>315</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>117</Hsp_identity>
      <Hsp_positive>172</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>305</Hsp_align-len>
      <Hsp_qseq>VGRVYAVGRHQVTVEEVLAEGGFAIVF--LVKT----SGGVRSALKRMYVNNEHDLKVCQREITIMKELSGHKNIVGYLDS-SINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQ-AHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPFGE-SQVAICDGNFTIPDHSRYSHEMHCLIRYMLEPDPDSRPEIYQVACFAFKLSGKECPILNVNGLSLP</Hsp_qseq>
      <Hsp_hseq>VGTQLTVGSHQVEIIKYLTSGGFAQVYSALINPPDPHSNSSVACLKRVIVPDKPSLNTLRAEVDAMRLLKNNRYVVSYIDSHAAKAMLHNGSYEVFVLMEYCERGGLIDFMNTRLQNRLHEFEILQIMSQVTQGVAAMHALQPPLIHRDIKIENVLISANNEYKLCDFGSVCGIIRPPRNSQELSYVQQDILKNTTAQYRSPEMIDTFRGLPIDEKSDIWALGIFLYKLCYYTTPFEKGGDLAILSGKFEFPLYPNYSEQLKGLIRDILVQDPRHRPNVYQLLKRISIMQNVPCPINDIQVVQAP</Hsp_hseq>
      <Hsp_midline>VG    VG HQV + + L  GGFA V+  L+      S    + LKR+ V ++  L   + E+  M+ L  ++ +V Y+DS +  A   +G +EV +LME C  G +++ MN RL     E E+L+I     + VA +H  + P+IHRD+K+EN+L+  N  Y LCDFGS    I  P+ +  +S V+ +I K TT  YR+PEM++ + G PI  KSDIWALG  LYKLC++T PF +   +AI  G F  P +  YS ++  LIR +L  DP  RP +YQ+      +    CPI ++  +  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YIL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:183937:186369:1 gene:YIL095W transcript:YIL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRK1 description:Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton and reduces endocytic ability of cell through the phosphorylation of the Pan1p-Sla1p-End3p protein complex; PRK1 has a paralog, ARK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001357]</Hit_def>
  <Hit_accession>YIL095W</Hit_accession>
  <Hit_len>810</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>213.772</Hsp_bit-score>
      <Hsp_score>543</Hsp_score>
      <Hsp_evalue>2.58402e-63</Hsp_evalue>
      <Hsp_query-from>103</Hsp_query-from>
      <Hsp_query-to>966</Hsp_query-to>
      <Hsp_hit-from>12</Hsp_hit-from>
      <Hsp_hit-to>307</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>111</Hsp_identity>
      <Hsp_positive>161</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>296</Hsp_align-len>
      <Hsp_qseq>GRVYAVGRHQVTVEEVLAEGGFAIVFLVKTS------GGVRSALKRMYVNNEHDLKVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQ-AHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPFGES-QVAICDGNFTIPDHSRYSHEMHCLIRYMLEPDPDSRPEIYQVACFAFKLSGKECPILN</Hsp_qseq>
      <Hsp_hseq>GTILTVGSHHAKIIKYLTSGGFAQVYTAEISPPDPYSNANIACLKRVIVPHKQGLNTLRAEVDAMKLLRNNKHVVSYIDSHAARSVNGIAYEVFVLMEFCERGGLIDFMNTRLQNRLQESEILEIMSQTVQGITAMHALQPPLIHRDIKIENVLISHDGLYKVCDFGSVSGVIRPPRNTQEFNYVQHDILTNTTAQYRSPEMIDLYRGLPIDEKSDIWALGVFLYKICYYTTPFEKSGEAGILHARYQYPSFPQYSDRLKNLIRLMLMEAPSQRPNICQVLEEVSRLQNKPCPIRN</Hsp_hseq>
      <Hsp_midline>G +  VG H   + + L  GGFA V+  + S          + LKR+ V ++  L   + E+  MK L  +K++V Y+DS      +   +EV +LME C  G +++ MN RL     E E+L I   T + +  +H  + P+IHRD+K+EN+L+  +G Y +CDFGS +  I  P+     + V+ +I   TT  YR+PEM++LY G PI  KSDIWALG  LYK+C++T PF +S +  I    +  P   +YS  +  LIR ML   P  RP I QV     +L  K CPI N</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YBR059C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:356861:360187:-1 gene:YBR059C transcript:YBR059C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AKL1 description:Ser-Thr protein kinase; member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization [Source:SGD;Acc:S000000263]</Hit_def>
  <Hit_accession>YBR059C</Hit_accession>
  <Hit_len>1108</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>199.519</Hsp_bit-score>
      <Hsp_score>506</Hsp_score>
      <Hsp_evalue>1.48627e-57</Hsp_evalue>
      <Hsp_query-from>103</Hsp_query-from>
      <Hsp_query-to>960</Hsp_query-to>
      <Hsp_hit-from>25</Hsp_hit-from>
      <Hsp_hit-to>327</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>120</Hsp_identity>
      <Hsp_positive>175</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>305</Hsp_align-len>
      <Hsp_qseq>GRVYAVGRHQVTVEEVLAEGGFAIVFLVK----------TSG-----GVRSALKRMYVNNEHDLKVCQREITIMKELSGHKNIVGYLDSSINAQTSSGV--WEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAH-GVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPFGES-QVAICDGNFTIPDHSRYSHEMHCLIRYMLEPDPDSRPEIYQVACFAFKLSGKECPI</Hsp_qseq>
      <Hsp_hseq>GHIVCVGTHKVEVVNYLAEGGFAQIYVVKFLEYLNEFDNTASVPLKIGDVACLKRVLVQDENGLNEMRNEVEVMKKLKGAPNIVQYFDSNA-SRRRDGVQGFEVLLLMELCPNKSLLDYMNQRLSTKLTEAEIVKIMYDVALSISQMHYLPVSLIHRDIKIENVLVDAKNNFKLADFGSTSTCFPIVTTHQDIALLTQNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGVFLYKLLFFTTPFEMTGQFAILHSKYEFPVN-KYSSKLINLIIIMLAENPNLRPNIYQVLYHLCEILNVEVPI</Hsp_hseq>
      <Hsp_midline>G +  VG H+V V   LAEGGFA +++VK          T+      G  + LKR+ V +E+ L   + E+ +MK+L G  NIV Y DS+  ++   GV  +EVL+LME+C    +++ MNQRLST  TE E+++I  D   +++++H     +IHRD+K+EN+L+    N+ L DFGS +        H  ++ +   I  +TT  YR+PEM++LY   PI  KSDIWALG  LYKL FFT PF  + Q AI    +  P + +YS ++  LI  ML  +P+ RP IYQV     ++   E PI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>98.5969</Hsp_bit-score>
      <Hsp_score>244</Hsp_score>
      <Hsp_evalue>4.58805e-23</Hsp_evalue>
      <Hsp_query-from>151</Hsp_query-from>
      <Hsp_query-to>933</Hsp_query-to>
      <Hsp_hit-from>88</Hsp_hit-from>
      <Hsp_hit-to>336</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>90</Hsp_identity>
      <Hsp_positive>126</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>273</Hsp_align-len>
      <Hsp_qseq>LAEGGFAIVFLVKTSGGVRSALK---RMYVNNEHDLKVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYT---TLSYRAPE-MVNLYNGTPITAKSDIWALGCLLYKLCFFTLPFGESQV-----AICDGNFTIPDHSRYSHEMHCLIRYMLEPDPDSRPEIYQVACFAF</Hsp_qseq>
      <Hsp_hseq>LGEGGFARCFQIKDDSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMS-HPNIVQFIDC---FEDDSNVY---ILLEICPNGSLMELLKRR--KVLTEPEVRFFTTQICGAIKYMHSRR--VIHRDLKLGNIFFDSNYNLKIGDFGLA----------AVLANESE-RKYTICGTPNYIAPEVLMGKHSGHSFEV--DIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRDKPISDEGKILIRDILSLDPIERPSLTEIMDYVW</Hsp_hseq>
      <Hsp_midline>L EGGFA  F +K   G   A K   +  + +E   K    EI I K +S H NIV ++D     +  S V+   IL+EIC  G ++  + +R     TE EV       C A+  +H  +  +IHRDLK+ NI    N N  + DFG A           V A E E +KYT   T +Y APE ++  ++G       DIW+LG +LY L     PF    V      I   +F+ P     S E   LIR +L  DP  RP + ++  + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YPL236C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:101608:102702:-1 gene:YPL236C transcript:YPL236C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ENV7 description:Vacuolar membrane protein kinase; negatively regulates membrane fusion; associates with vacuolar membrane through palmitoylation of one or more cysteines in consensus sequence; vacuolar membrane association is essential to its kinase activity; mutant shows defect in CPY processing; ortholog of human serine/threonine kinase 16 (STK16) [Source:SGD;Acc:S000006157]</Hit_def>
  <Hit_accession>YPL236C</Hit_accession>
  <Hit_len>364</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.5817</Hsp_bit-score>
      <Hsp_score>218</Hsp_score>
      <Hsp_evalue>3.39104e-20</Hsp_evalue>
      <Hsp_query-from>94</Hsp_query-from>
      <Hsp_query-to>903</Hsp_query-to>
      <Hsp_hit-from>17</Hsp_hit-from>
      <Hsp_hit-to>350</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>83</Hsp_identity>
      <Hsp_positive>136</Hsp_positive>
      <Hsp_gaps>68</Hsp_gaps>
      <Hsp_align-len>336</Hsp_align-len>
      <Hsp_qseq>AFVGRVYAVGRHQVTVEEVLAEGGFAIVFLVKTS-------GGVRS----ALKRMYVNNEHDLKVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTG--FTECEVLRIFCDTCEAVARLHQC-----------------------------KTPI---------------IHRDLKVENILLHDNGNYVLCDFGSATN-KILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPFG-ESQV-------AICDGNFTIPDHSRYSHEMHCLIRYMLEPDPDSRP</Hsp_qseq>
      <Hsp_hseq>GFSDATIRVNDKRYRIQRLLGEGGMSFVYLVQLSKNSLIIDNGIATPELYALKKIICPSVESISNGMREIENYKRFQS-PYVIKSIDSQV-MQEKDGSKTIYIVLPYYSLGSLQDSINRRLLEGTFVSEAECVRIMLGVTRGLLCLHDPASRQDNATSRVNVDAVSMTYSDETAMLLEDTPLEMDMLSSNSAGSIAYAHRDITPSNILFSSDGLPVIGDLGSCSQADITIENRHQLSELQEWVNDNCTLPYTPPELLNLKLNQVLSSKVDIWSLGCTFYTLMFGISPFEREEQIHGASLTYAINTGKYSFPRNSRFSEGLLSVIKKCIQVDPIQRP</Hsp_hseq>
      <Hsp_midline> F      V   +  ++ +L EGG + V+LV+ S        G+ +    ALK++   +   +    REI   K       ++  +DS +  Q   G   + I++     G + + +N+RL  G   +E E +RI       +  LH                                TP+                HRD+   NIL   +G  V+ D GS +   I     H +S +++ +    TL Y  PE++NL     +++K DIW+LGC  Y L F   PF  E Q+       AI  G ++ P +SR+S  +  +I+  ++ DP  RP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.4185</Hsp_bit-score>
      <Hsp_score>202</Hsp_score>
      <Hsp_evalue>1.30647e-17</Hsp_evalue>
      <Hsp_query-from>256</Hsp_query-from>
      <Hsp_query-to>900</Hsp_query-to>
      <Hsp_hit-from>78</Hsp_hit-from>
      <Hsp_hit-to>277</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>231</Hsp_align-len>
      <Hsp_qseq>CQREITIMKELSGHKNIVGYLDSSINAQTSSGVWE----VLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTL----SYRAPEMVNLYNGTPITA-KSDIWALGCLLYKLCFFTLPFGESQ-------VAICDGNFTIPDHSRYSHEMHCLIRYMLEPDPDSR</Hsp_qseq>
      <Hsp_hseq>IEREIIIMK-LLNHPNVLRLYD----------VWETNTDLYLVLEYAEKGELFNLLVER--GPLPEHEAIRFFRQIIIGVSYCHALG--IVHRDLKPENLLLDHKYNIKIADFGMA-------------ALETEGKLLETSCGSPHYAAPEIV---SGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERR</Hsp_hseq>
      <Hsp_midline> +REI IMK L  H N++   D          VWE    + +++E    G++ N + +R      E E +R F      V+  H     I+HRDLK EN+LL    N  + DFG A             A+E E K   T      Y APE+V   +G P     SD+W+ G +L+ L    LPF E         + +  G F +P     S E   LIR +L  DP+ R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.4034</Hsp_bit-score>
      <Hsp_score>176</Hsp_score>
      <Hsp_evalue>2.55177e-14</Hsp_evalue>
      <Hsp_query-from>130</Hsp_query-from>
      <Hsp_query-to>783</Hsp_query-to>
      <Hsp_hit-from>24</Hsp_hit-from>
      <Hsp_hit-to>218</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>222</Hsp_align-len>
      <Hsp_qseq>QVTVEEVLAEGGFAIVF-LVKTSGGVRSALKRMYVNNEHDLKVCQREITIMKELSGHKNIV---GYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPF</Hsp_qseq>
      <Hsp_hseq>QYHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNL-NHNNIVKYHGFIRKS---------YELYILLEYCANGSL-RRLISRSSTGLSENESKTYVTQTLLGLKYLH--GEGVIHRDIKAANILLSADNTVKLADFGVST--IVNSSALTLAG---------TLNWMAPEILGNRGASTL---SDIWSLGATVVEMLTKNPPY</Hsp_hseq>
      <Hsp_midline>Q  +++V+  G + +V+  +        A+K +   N+ +L     EI+++K L  H NIV   G++  S         +E+ IL+E C  G +  ++  R STG +E E       T   +  LH     +IHRD+K  NILL  +    L DFG +T  I+N  A  ++          TL++ APE++     + +   SDIW+LG  + ++     P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>3.04185e-14</Hsp_evalue>
      <Hsp_query-from>106</Hsp_query-from>
      <Hsp_query-to>753</Hsp_query-to>
      <Hsp_hit-from>31</Hsp_hit-from>
      <Hsp_hit-to>240</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>225</Hsp_align-len>
      <Hsp_qseq>RVYAVGRHQVTVEEVLAEGGFAIVFLVKTSG---GVRSALKRM--YVNNEHDLKVCQREITIMKELSGHKNIVGYLDSSI-NAQTSSGVW--EVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKY-TTLSYRAPEMVNLYNGTPITAKSDIWALGCLL</Hsp_qseq>
      <Hsp_hseq>RISIPGYYEII--QFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGHKNIVNLIDLEIVTSSPYDGLYCYQELIDYDLAK----VIHSSVQLSEFHIKYFLYQILC----GLKYIHSAD--VIHRDLKPGNILCTLNGCLKICDFGLARG-IHAGFFKCHSTVQPHITNYVATRWYRAPEL--LLSNQPYSKSVDIWAVGCIL</Hsp_hseq>
      <Hsp_midline>R+   G +++   + L +G +  V  VK  G     R A+K++    N E  LK   RE+  M    GHKNIV  +D  I  +    G++  + LI  ++ +    V   + +LS    +  + +I C     +  +H     +IHRDLK  NIL   NG   +CDFG A   I        S V+  I  Y  T  YRAPE+  L +  P +   DIWA+GC+L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>4.55794e-14</Hsp_evalue>
      <Hsp_query-from>340</Hsp_query-from>
      <Hsp_query-to>933</Hsp_query-to>
      <Hsp_hit-from>103</Hsp_hit-from>
      <Hsp_hit-to>286</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>210</Hsp_align-len>
      <Hsp_qseq>TSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVN--LYNGTPITAKSDIWALGCLLYKLCFFTLPFGESQVAICDGNF----------TIPDHSRYSHEMHCLIRYMLEPDPDSRPEIYQVACFAF</Hsp_qseq>
      <Hsp_hseq>TESKVW---MALEYCPGKELYDHLLSLRRISLLECGEL--FAQISGAVYYAHSMH--CVHRDLKLENILLDKNGNAKLTDFGFTRECMTKTTLETVCG---------TTVYMAPELIERRTYDGFKI----DIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDAKVIPDDAR------DLISRLLAKNPGERPSLSQVLRHPF</Hsp_hseq>
      <Hsp_midline>T S VW   + +E C   ++ + +         EC  L  F     AV   H      +HRDLK+ENILL  NGN  L DFG     +       V           T  Y APE++    Y+G  I    DIW+LG +LY L    LPF +   A                 IPD +R       LI  +L  +P  RP + QV    F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>1.23617e-13</Hsp_evalue>
      <Hsp_query-from>232</Hsp_query-from>
      <Hsp_query-to>891</Hsp_query-to>
      <Hsp_hit-from>227</Hsp_hit-from>
      <Hsp_hit-to>427</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>231</Hsp_align-len>
      <Hsp_qseq>NNEHDLKVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQ------VVNQMNQRLS-----TGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPFGESQVAICDGNFTIPDHSRYSHEMHCLIRYMLEPDP</Hsp_qseq>
      <Hsp_hseq>NNSTIINQLVRELSIVKNVKPHENIITFYGAYYNQHINN---EIIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYR-QYKIIHRDIKPSNVLINSKGQIKLCDFG-VSKKLINSIADTFVG---------TSTYMSPERI---QGNVYSIKGDVWSLGLMIIELVTGEFPLG--------GHNDTPDGI-----LDLLQRIVNEPSP</Hsp_hseq>
      <Hsp_midline>NN   +    RE++I+K +  H+NI+ +  +  N   ++   E++ILME    G       V  +  QR +     T F E  + +I       +  L++ +  IIHRD+K  N+L++  G   LCDFG  + K++N  A              T +Y +PE +    G   + K D+W+LG ++ +L     P G        G+   PD       +  L R + EP P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>2.16403e-13</Hsp_evalue>
      <Hsp_query-from>250</Hsp_query-from>
      <Hsp_query-to>900</Hsp_query-to>
      <Hsp_hit-from>60</Hsp_hit-from>
      <Hsp_hit-to>269</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>226</Hsp_align-len>
      <Hsp_qseq>KVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRI-FCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCF----FTLPFGESQVAIC----DGNFTIPDHSRYSHEMHCLIRYMLEPDPDSR</Hsp_qseq>
      <Hsp_hseq>KDITKEVVLQSKCSKHPNVLRLIDCNVSKEY---MW---IILEMADGGDLFDKIEPDVGV---DSDVAQFYFQQLVSAINYLH-VECGVAHRDIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVS-----MDQRGSPPYMAPEVLYSEEGY-YADRTDIWSIGILLFVLLTGQTPWELPSLENEDFVFFIENDGNLNWGPWSKIEFTHLNLLRKILQPDPNKR</Hsp_hseq>
      <Hsp_midline>K   +E+ +  + S H N++  +D +++ +    +W   I++E+   G + +++   +     + +V +  F     A+  LH  +  + HRD+K ENILL  NGN  L DFG A+          VS     + +  +  Y APE++    G     ++DIW++G LL+ L      + LP  E++  +     DGN      S+       L+R +L+PDP+ R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>3.57528e-13</Hsp_evalue>
      <Hsp_query-from>256</Hsp_query-from>
      <Hsp_query-to>918</Hsp_query-to>
      <Hsp_hit-from>74</Hsp_hit-from>
      <Hsp_hit-to>279</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>237</Hsp_align-len>
      <Hsp_qseq>CQREITIMKELSGHKNIVGYLDSSINAQTSSGVWE----VLILMEICRAGQVVNQMNQRLSTG-FTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSA---TNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITA-KSDIWALGCLLYKLCFFTLPFGESQVAICD-------GNFTIPDHSRYSHEMHCLIRYMLEPDPDSRPEIYQV</Hsp_qseq>
      <Hsp_hseq>IEREIVIMKLLS-HPNVLSLYD----------VWETNNNLYLILEYAEKGELFNLL---VDHGPLPEREAINCFRQIIIGISYCHALG--IVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCG------------SPHYAAPEIV---SGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDI</Hsp_hseq>
      <Hsp_midline> +REI IMK LS H N++   D          VWE    + +++E    G++ N +   +  G   E E +  F      ++  H     I+HRDLK EN+LL    N  + DFG A   T+  L   + G            +  Y APE+V   +G P     SD+W+ G +L+ L    LPF E    + D       G F +P+ +  S +   LI  +L  DP  R +I  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>4.40689e-13</Hsp_evalue>
      <Hsp_query-from>145</Hsp_query-from>
      <Hsp_query-to>765</Hsp_query-to>
      <Hsp_hit-from>12</Hsp_hit-from>
      <Hsp_hit-to>206</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>217</Hsp_align-len>
      <Hsp_qseq>EVLAEGGFAIVF----LVKTSGGVRSALKRMYVNNEHD--LKVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYT----TLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLC</Hsp_qseq>
      <Hsp_hseq>EKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDL-DLKRYMEGIPK-DQPLGADI----VKKFMMQLCKGIAYCHSHR--ILHRDLKPQNLLINKDGNLKLGDFGLA-------RAFGVP-----LRAYTHEIVTLWYRAPEV--LLGGKQYSTGVDTWSIGCIFAEMC</Hsp_hseq>
      <Hsp_midline>E + EG + +V+    L    G    ALK++ + +E +       REI+++KEL     +  Y     +A     V+E L L ++ R  + + + +Q L        V +     C+ +A  H  +  I+HRDLK +N+L++ +GN  L DFG A       +A GV      ++ YT    TL YRAPE+  L  G   +   D W++GC+  ++C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>6.30984e-13</Hsp_evalue>
      <Hsp_query-from>130</Hsp_query-from>
      <Hsp_query-to>765</Hsp_query-to>
      <Hsp_hit-from>12</Hsp_hit-from>
      <Hsp_hit-to>220</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>218</Hsp_align-len>
      <Hsp_qseq>QVTVEEVLAEGGFAIV-FLVKTSGGVRSALKRMYVNNEHDLKVCQ--REITIMKELSGHKNIVGYLDS--SINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKY-TTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLC</Hsp_qseq>
      <Hsp_hseq>QYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKK-LFVTRTIREIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELME-TDLQKVINNQNSGFST-LSDDHVQYFTYQILRALKSIHSAQ--VIHRDIKPSNLLLNSNCDLKVCDFGLA--RCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQE--YTTAMDIWSCGCILAEMV</Hsp_hseq>
      <Hsp_midline>Q  + +++ EG +  V   +    G++ A+K++   ++  L V +  REI +++    H+NI+  LD    ++    + V+ V  LME     +V+N  N   ST  ++  V         A+  +H  +  +IHRD+K  N+LL+ N +  +CDFG A  + L   +     +   + +Y  T  YRAPE++  +     T   DIW+ GC+L ++ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>9.33863e-13</Hsp_evalue>
      <Hsp_query-from>103</Hsp_query-from>
      <Hsp_query-to>783</Hsp_query-to>
      <Hsp_hit-from>558</Hsp_hit-from>
      <Hsp_hit-to>768</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>233</Hsp_align-len>
      <Hsp_qseq>GRVYAVGRHQVTVEEVLAEGGFAIVFLVKTSGGVRSALKRMYVNNEHDLKVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVV--NQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTL----SYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPF</Hsp_qseq>
      <Hsp_hseq>GSVYLAERTHIPTESNMIE--LINNDIDEPHVGDKVAIKQMVLSKQPRKELIVNEILVMKD-SRHKNIVNFLEAYL--RTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKH--IIHRDIKSDNVLLDTRARVKITDFG------------FCARLTDKRSKRATMVGTPYWMAPEVVKQRE---YDEKIDVWSLGIMTIEMLEGEPPY</Hsp_hseq>
      <Hsp_midline>G VY   R  +  E  + E       + +   G + A+K+M ++ +   ++   EI +MK+ S HKNIV +L++ +  +T   +W V+  ME      ++  +  N    +  TE ++  I  +TC+ +  LH     IIHRD+K +N+LL       + DFG              + + D+  K  T+     + APE+V          K D+W+LG +  ++     P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>9.54229e-13</Hsp_evalue>
      <Hsp_query-from>118</Hsp_query-from>
      <Hsp_query-to>918</Hsp_query-to>
      <Hsp_hit-from>52</Hsp_hit-from>
      <Hsp_hit-to>300</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>135</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>278</Hsp_align-len>
      <Hsp_qseq>VGRHQVTVEEVLAEGGFAIVFLV-KTSGGVRSALK--RMYVNNEHDLK-VCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVN--LYNGTPITAKSDIWALGCLLYKLCFFTLPFGESQVA-----ICDGNFTIPDHSRYSHEMHCLIRYMLEPDPDSRPEIYQV</Hsp_qseq>
      <Hsp_hseq>IGNYQIV--KTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLR-HPHIIKLYDV-IKSKD-----EIIMVIEYA-GNELFDYIVQR--DKMSEQEARRFFQQIISAVEYCHRHK--IVHRDLKPENLLLDEHLNVKIADFG-LSNIMTDGNFLKTSC--------GSPNYAAPEVISGKLYAGPEV----DVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKF--LSPGAAGLIKRMLIVNPLNRISIHEI</Hsp_hseq>
      <Hsp_midline>+G +Q+   + L EG F  V L   T+ G + ALK     V  + D++   +REI+ ++ L  H +I+   D  I ++      E+++++E     ++ + + QR     +E E  R F     AV   H+ K  I+HRDLK EN+LL ++ N  + DFG  +N + +      S          + +Y APE+++  LY G  +    D+W+ G +LY +    LPF +  +      I +G +T+P     S     LI+ ML  +P +R  I+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>1.56275e-12</Hsp_evalue>
      <Hsp_query-from>160</Hsp_query-from>
      <Hsp_query-to>966</Hsp_query-to>
      <Hsp_hit-from>1043</Hsp_hit-from>
      <Hsp_hit-to>1330</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>82</Hsp_identity>
      <Hsp_positive>139</Hsp_positive>
      <Hsp_gaps>53</Hsp_gaps>
      <Hsp_align-len>305</Hsp_align-len>
      <Hsp_qseq>GGFAIVF-LVKTSGGVRSALKRMYVNNEHDLK----VCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECE-VLRIFC-DTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGV--SAVED---EIKKYT----TLSYRAPEMVNLYNGTPITAK---SDIWALGCLLYKLCFFTLPFG--ESQVAI----CDGNF-TIPDHSRYSHEMHCLIRYMLEPDPDSR---------PEIYQVACFAFKLSGK-ECPILN</Hsp_qseq>
      <Hsp_hseq>GTFGQVYSAINLENGEILAVKEIKIHDTTTMKKIFPLIKEEMTVL-EMLNHPNIVQYYGVEVHRD------KVNIFMEYCEGGSLASLLDH----GRIEDEMVTQVYTFELLEGLAYLHQ--SGVVHRDIKPENILLDFNGIIKYVDFGTART-VVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETI---SGSAVKGKLGADDVWALGCVVLEMATGRRPWSNLDNEWAIMYHVAAGRIPQLPNRDEMTAAGRAFLERCLVQDPTMRATAVELLIDPWMIQIREIAFGNSEKDQVPILS</Hsp_hseq>
      <Hsp_midline>G F  V+  +    G   A+K + +++   +K    + + E+T++ E+  H NIV Y    ++        +V I ME C  G + + ++     G  E E V +++  +  E +A LHQ  + ++HRD+K ENILL  NG     DFG+A   ++  +   V  +AV+D   E K       T  Y APE +   +G+ +  K    D+WALGC++ ++     P+   +++ AI      G    +P+    +      +   L  DP  R         P + Q+   AF  S K + PIL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>2.38143e-12</Hsp_evalue>
      <Hsp_query-from>262</Hsp_query-from>
      <Hsp_query-to>762</Hsp_query-to>
      <Hsp_hit-from>71</Hsp_hit-from>
      <Hsp_hit-to>226</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>171</Hsp_align-len>
      <Hsp_qseq>REITIMKELSGHKNIVGYLDSSINAQTS---SGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKY-TTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKL</Hsp_qseq>
      <Hsp_hseq>RELKLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLYEELME-CDLSQII-RSEQRLEDAHFQSFIYQILC----ALKYIHSAN--VLHCDLKPKNLLVNSDCQLKICNFGLSCSYSEN---HKVN--DGFIKGYITSIWYKAPEI--LLNYQECTKAVDIWSTGCILAEL</Hsp_hseq>
      <Hsp_midline>RE+ +++ L GH NIV   D+ I    +   +GV+    LME C   Q++ +  QRL     +  + +I C    A+  +H     ++H DLK +N+L++ +    +C+FG + +   N   H V+  +  IK Y T++ Y+APE+  L N    T   DIW+ GC+L +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>2.73259e-12</Hsp_evalue>
      <Hsp_query-from>94</Hsp_query-from>
      <Hsp_query-to>903</Hsp_query-to>
      <Hsp_hit-from>24</Hsp_hit-from>
      <Hsp_hit-to>288</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>79</Hsp_identity>
      <Hsp_positive>124</Hsp_positive>
      <Hsp_gaps>53</Hsp_gaps>
      <Hsp_align-len>294</Hsp_align-len>
      <Hsp_qseq>AFVGRVYAVGRHQVTVEEVLAEGGFAIVFLVKTSG-----GVRSALKRMYVNNEHDLKVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVW-----EVLILMEICRAGQVVNQMNQRLSTG-FTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGN---YVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLY-NGTPITAKSDIWALGCLLYK-LCFFTLPFGESQVAICD----GNFTIPDHSRY----SHEMHCLIRYMLEPDPDSRP</Hsp_qseq>
      <Hsp_hseq>AHVQPASYVNKKKYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLH-HPNIVAFKD-----------WFESKDKFYIITQLAKGGELFDRI---LKKGKFTEEDAVRILVEILSAVKYMHSQN--IVHRDLKPENLLYIDKSDESPLVVADFGIA--KRLK------SDEELLYKPAGSLGYVAPEVLTQDGHGKPC----DIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNKAKQFILKALNLDPSKRP</Hsp_hseq>
      <Hsp_midline>A V     V + +    + L  G F +V   K +       V+  +K+    N+  L+    E+ I++ L  H NIV + D           W     +  I+ ++ + G++ +++   L  G FTE + +RI  +   AV  +H     I+HRDLK EN+L  D  +    V+ DFG A  K L       S  E   K   +L Y APE++    +G P     DIW++G + Y  LC ++    E      D    G + +  H  Y    S++    I   L  DP  RP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>2.91087e-12</Hsp_evalue>
      <Hsp_query-from>142</Hsp_query-from>
      <Hsp_query-to>813</Hsp_query-to>
      <Hsp_hit-from>63</Hsp_hit-from>
      <Hsp_hit-to>292</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>247</Hsp_align-len>
      <Hsp_qseq>EEVLAEGGFAIVFL-VKTSGGVRSALKRMYVNNEHDL--KVCQREITIMKELSGHKNIVGYL----DSS---INAQTSS---GVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSA------TNKILNPQAHGVSAVEDEIKKYT----TLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPFGESQVAICDG</Hsp_qseq>
      <Hsp_hseq>DEKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLN-HKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVL---HNPRIN--LEMCDIKNMMLQILEGLNYIHCAK--FMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGA------KYTSVVVTRWYRAPELV--LGDKQYTTAVDIWGVGCVFAEF-FEKKPILQGKTDIDQG</Hsp_hseq>
      <Hsp_midline>+E L +G F  V+  +      + A+K++ V+ E DL     QREITI+K L+ HKNI+  +    D S    NA +S+     + +L  M    +G +    N R++     C++  +     E +  +H  K   +HRD+K  NIL+  NG   L DFG A         +  P   G  A      KYT    T  YRAPE+V        T   DIW +GC+  +  F   P  + +  I  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>3.51354e-12</Hsp_evalue>
      <Hsp_query-from>262</Hsp_query-from>
      <Hsp_query-to>753</Hsp_query-to>
      <Hsp_hit-from>71</Hsp_hit-from>
      <Hsp_hit-to>223</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>REITIMKELSGHKNI--------VGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITAKSDIWALGCLL</Hsp_qseq>
      <Hsp_hseq>RELKLLRHFRGHKNITCLYDMDIVFYPDGSIN-----GLYLYEELME-CDMHQII-KSGQPLTDAHYQSFTYQILC----GLKYIHSAD--VLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTE----YVATRWYRAPEIMLSYQG--YTKAIDVWSAGCIL</Hsp_hseq>
      <Hsp_midline>RE+ +++   GHKNI        V Y D SIN     G++    LME C   Q++ +  Q L+    +    +I C     +  +H     ++HRDLK  N+L++ +    +CDFG A     NP  +     E       T  YRAPE++  Y G   T   D+W+ GC+L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>4.33094e-12</Hsp_evalue>
      <Hsp_query-from>145</Hsp_query-from>
      <Hsp_query-to>900</Hsp_query-to>
      <Hsp_hit-from>27</Hsp_hit-from>
      <Hsp_hit-to>264</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>118</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>266</Hsp_align-len>
      <Hsp_qseq>EVLAEGGFAIVFL---VKTSGGVRSALKRMYVNNEHD-LKVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTG-FTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYT---TLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPFGE------SQVAICDGNFTIPDHSRYSHEMHCLIRYMLEPDPDSR</Hsp_qseq>
      <Hsp_hseq>EVIGRGKFGVVYKGYNVKT--GRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLK---DTSLW---IIMEHCAGGS----LRSLLRPGKIDEKYIGVIMRELLVALKCIH--KDNVIHRDIKAANVLITNEGNVKLCDFGVAA------QVNQTS-----LRRQTMAGTPYWMAPEVI--MEGVYYDTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIKSKPPRLEDRS-YSTSLKEFIALCLDEDPKER</Hsp_hseq>
      <Hsp_midline>EV+  G F +V+    VKT  G   A+K + ++++ D ++  QREI  +  L    NI  Y  S +     + +W   I+ME C  G     +   L  G   E  +  I  +   A+  +H  K  +IHRD+K  N+L+ + GN  LCDFG A       Q +  S     +++ T   T  + APE++    G     K DIW+LG   Y++     P+ +       Q+ I      + D S YS  +   I   L+ DP  R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>5.53625e-12</Hsp_evalue>
      <Hsp_query-from>145</Hsp_query-from>
      <Hsp_query-to>762</Hsp_query-to>
      <Hsp_hit-from>43</Hsp_hit-from>
      <Hsp_hit-to>233</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>210</Hsp_align-len>
      <Hsp_qseq>EVLAEGGFAIVF-LVKTSGGVRSALKRMYVNNEHDLKVCQREITIMKELSGHKNIVG--YLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLH-DNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKL</Hsp_qseq>
      <Hsp_hseq>EVVGHGSFGVVFATVIQETNEKVAIKKVL----QDKRFKNRELEIMKMLS-HINIIDLKYFFYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQR--TPMSRLEIKYYMFQLFKSLNYLHHFAN-VCHRDIKPQNLLVDPETWSLKLCDFGSA--KQLKPTEPNVSYI-------CSRYYRAPELI--FGATNYTNQIDIWSSGCVMAEL</Hsp_hseq>
      <Hsp_midline>EV+  G F +VF  V      + A+K++      D +   RE+ IMK LS H NI+   Y     ++Q    +  +L  M      ++ + ++QR  T  +  E+        +++  LH     + HRD+K +N+L+  +  +  LCDFGSA  K L P    VS +        +  YRAPE++  +  T  T + DIW+ GC++ +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>5.63881e-12</Hsp_evalue>
      <Hsp_query-from>94</Hsp_query-from>
      <Hsp_query-to>783</Hsp_query-to>
      <Hsp_hit-from>40</Hsp_hit-from>
      <Hsp_hit-to>249</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>54</Hsp_gaps>
      <Hsp_align-len>247</Hsp_align-len>
      <Hsp_qseq>AFVGRV-YAVGRHQVTVEEVLAEGGFAIVFLVKTSG-----GVRSALKRMYVNNEHDLKVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVW-----EVLILMEICRAGQVVNQMNQRLSTG-FTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHD---NGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYT-TLSYRAPEMVNLY-NGTPITAKSDIWALGCLLYKLCFFTLPF</Hsp_qseq>
      <Hsp_hseq>SYVNRTNYIFGR-------TLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLS-HPNIVSFKD-----------WFESKDKFYIVTQLATGGELFDRI---LSRGKFTEVDAVEIIVQILGAVEYMHSKN--VVHRDLKPENVLYVDKSENSPLVIADFGIAKQ---------LKGEEDLIYKAAGSLGYVAPEVLTQDGHGKP----CDIWSIGVITYTLLCGYSPF</Hsp_hseq>
      <Hsp_midline>++V R  Y  GR        L  G F +V   +         ++  LK+    N   L++   E++I+++LS H NIV + D           W     +  I+ ++   G++ +++   LS G FTE + + I      AV  +H     ++HRDLK EN+L  D   N   V+ DFG A           +   ED I K   +L Y APE++    +G P     DIW++G + Y L     PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>6.47807e-12</Hsp_evalue>
      <Hsp_query-from>148</Hsp_query-from>
      <Hsp_query-to>783</Hsp_query-to>
      <Hsp_hit-from>184</Hsp_hit-from>
      <Hsp_hit-to>389</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>221</Hsp_align-len>
      <Hsp_qseq>VLAEGGFAIVFLVKTSGGVR----SALKRMYVNNEHDLKVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYT-----TLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPF</Hsp_qseq>
      <Hsp_hseq>VIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVV-RLFSTFQDESS-----LYFLLEYAPNGDFLSLMKKYGS--LDETCARYYAAQIIDAIDYLHS--NGIIHRDIKPENILLDGEMKIKLTDFGTA--KLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELL---NDSFTDYRCDIWAFGCILFQMIAGKPPF</Hsp_hseq>
      <Hsp_midline>V+ +G ++ V L  +    +      L + Y+  +  +K    E T +++L+   ++V  L S+   ++S     +  L+E    G  ++ M +  S    E           +A+  LH     IIHRD+K ENILL       L DFG+A  K+LNP  + VS  E ++   +     T  Y +PE++   N +    + DIWA GC+L+++     PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>7.19991e-12</Hsp_evalue>
      <Hsp_query-from>145</Hsp_query-from>
      <Hsp_query-to>762</Hsp_query-to>
      <Hsp_hit-from>11</Hsp_hit-from>
      <Hsp_hit-to>202</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>214</Hsp_align-len>
      <Hsp_qseq>EVLAEGGFAIVF--LVKTSGGVRSALKRMYVNNEHDL-KVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFT----ECEVLRIF-CDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKL</Hsp_qseq>
      <Hsp_hseq>EKLGNGTYATVYKGLNKTTG-VYVALKEVKLDSEEGTPSTAIREISLMKELK-HENIVRLYDVIHTENKLTLVFEFM-------DNDLKKYMDSR-TVGNTPRGLELNLVKYFQWQLLQGLAFCHENK--ILHRDLKPQNLLINKRGQLKLGDFGLA-------RAFGI-PVNTFSSEVVTLWYRAPDV--LMGSRTYSTSIDIWSCGCILAEM</Hsp_hseq>
      <Hsp_midline>E L  G +A V+  L KT+G V  ALK + +++E        REI++MKEL  H+NIV   D        + V+E +          +   M+ R + G T    E  +++ F     + +A  H+ K  I+HRDLK +N+L++  G   L DFG A       +A G+  V     +  TL YRAP++  L      +   DIW+ GC+L ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>1.1228e-11</Hsp_evalue>
      <Hsp_query-from>259</Hsp_query-from>
      <Hsp_query-to>900</Hsp_query-to>
      <Hsp_hit-from>162</Hsp_hit-from>
      <Hsp_hit-to>357</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>227</Hsp_align-len>
      <Hsp_qseq>QREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTG-FTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYV-LCDFGSAT----NKILNPQAHGVSAVEDEIKKYTTLSYRAPEMV--NLYNGTPITAKSDIWALGCLLYKLCFFTLPFGESQV-----AICDGNFTIPDHSRYSHEMHCLIRYMLEPDPDSR</Hsp_qseq>
      <Hsp_hseq>EREIVIMKLIS-HTNVMALFEVWENKS------ELYLVLEYVDGGELFDYL---VSKGKLPEREAIHYFKQIVEGVSYCHSFN--ICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTSC-------------GSPHYASPEIVMGRPYHGGP----SDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMP--SNLSSEARDLISKILVIDPEKR</Hsp_hseq>
      <Hsp_midline>+REI IMK +S H N++   +   N        E+ +++E    G++ + +   +S G   E E +  F    E V+  H     I HRDLK EN+LL      + + DFG A     NK+L                  +  Y +PE+V    Y+G P    SD+W+ G +L+ L    LPF +  +      +  G + +P  S  S E   LI  +L  DP+ R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>1.12589e-11</Hsp_evalue>
      <Hsp_query-from>199</Hsp_query-from>
      <Hsp_query-to>783</Hsp_query-to>
      <Hsp_hit-from>400</Hsp_hit-from>
      <Hsp_hit-to>582</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>205</Hsp_align-len>
      <Hsp_qseq>GVRSALKRMYVNNEHDLKVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQ--RLSTG-----FTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYT---TLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPF</Hsp_qseq>
      <Hsp_hseq>GERVAIKQIRLSEQPKKQLIMNELLVMND-SRQENIVNFLEAYIIDDE-----ELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKK--IIHRDIKSDNILLNSQGLVKITDFGFC-----------VELTEKRSKRATMVGTPYWMAPEIV---NQKGYDEKVDVWSLGIMLIEMIEGEPPY</Hsp_hseq>
      <Hsp_midline>G R A+K++ ++ +   ++   E+ +M + S  +NIV +L++ I         E+ ++ME    G + + ++   R +TG       E ++  I  +TC+ +  LH  K  IIHRD+K +NILL+  G   + DFG             V   E   K+ T   T  + APE+V   N      K D+W+LG +L ++     P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>2.07719e-11</Hsp_evalue>
      <Hsp_query-from>439</Hsp_query-from>
      <Hsp_query-to>918</Hsp_query-to>
      <Hsp_hit-from>949</Hsp_hit-from>
      <Hsp_hit-to>1093</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>162</Hsp_align-len>
      <Hsp_qseq>ECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMV--NLYNGTPITAKSDIWALGCLLYKLCFFTLPFGESQVAICDGNFTIPDHSRYSHEMHCLIRYMLEPDPDSRPEIYQV</Hsp_qseq>
      <Hsp_hseq>EHEAKLVFKQVVASIKHLHDQG--IVHRDIKDENVIVDSHGFVKLIDFGSAAYIKSGPFDVFVG----------TMDYAAPEVLGGSSYKGKP----QDIWALGVLLYTIIYKENPYYNID-EILEGELRFDKSEHVSEECISLIKRILTREVDKRPTIDEI</Hsp_hseq>
      <Hsp_midline>E E   +F     ++  LH     I+HRD+K EN+++  +G   L DFGSA      P    V           T+ Y APE++  + Y G P     DIWALG LLY + +   P+      I +G          S E   LI+ +L  + D RP I ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>2.13195e-11</Hsp_evalue>
      <Hsp_query-from>109</Hsp_query-from>
      <Hsp_query-to>933</Hsp_query-to>
      <Hsp_hit-from>117</Hsp_hit-from>
      <Hsp_hit-to>390</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>118</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>293</Hsp_align-len>
      <Hsp_qseq>VYAVGRHQVTVEEVLAEGGFAIVFLVKT-SGGVRSALK---RMYVNNEHDLKVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYT-------TLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPFGES-------QVAICDGNFTIPDHSRYSHEMHCLIRYMLEPDPDSRPEIYQVACFAF</Hsp_qseq>
      <Hsp_hseq>VVKMGIKDFKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQKLNGTKGIFKLF---FTFQDEASLY---FLLEYAPHGDFLGLIKKYGS--LNETCARYYASQIIDAVDSLHNIG--IIHRDIKPENILLDKNMKVKLTDFGTA--KILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPE---LLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKIQYAFT----AGFPQIVKDLVKKLLVRDPNDRLTIKQIKAHLF</Hsp_hseq>
      <Hsp_midline>V  +G       E L +G ++ V L      G + A+K   + Y+  +  +K    E   +++L+G K I          Q  + ++    L+E    G  +  + +  S    E           +AV  LH     IIHRD+K ENILL  N    L DFG+A  KIL  +    +  +     Y        T  Y +PE   L N     ++ DIWA GC+LY++     PF  +       +V      FT    + +   +  L++ +L  DP+ R  I Q+    F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>2.56119e-11</Hsp_evalue>
      <Hsp_query-from>145</Hsp_query-from>
      <Hsp_query-to>798</Hsp_query-to>
      <Hsp_hit-from>1179</Hsp_hit-from>
      <Hsp_hit-to>1385</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>227</Hsp_align-len>
      <Hsp_qseq>EVLAEGGFAIVFL-VKTSGGVRSALKRMYV-----NNEHDLKVCQ---REITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPFGESQV</Hsp_qseq>
      <Hsp_hseq>EMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLD-HLNIVQYL----GFENKNNIYS--LFLEYVAGGSVGSLI--RMYGRFDEPLIKHLTTQVLKGLAYLHS--KGILHRDMKADNLLLDQDGICKISDFG------ISRKSKDIYSNSDMTMRGTVF-WMAPEMVDTKQG--YSAKVDIWSLGCIVLEMFAGKRPWSNLEV</Hsp_hseq>
      <Hsp_midline>E++ +G F  V+L +  + G   A+K++ V      NE  L   +    E++ +K+L  H NIV YL      +  + ++   + +E    G V + +  R+   F E  +  +     + +A LH     I+HRD+K +N+LL  +G   + DFG      ++ ++  + +  D   + T   + APEMV+   G   +AK DIW+LGC++ ++     P+   +V</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>3.13285e-11</Hsp_evalue>
      <Hsp_query-from>367</Hsp_query-from>
      <Hsp_query-to>999</Hsp_query-to>
      <Hsp_hit-from>221</Hsp_hit-from>
      <Hsp_hit-to>415</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>222</Hsp_align-len>
      <Hsp_qseq>ILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTT----LSYRAPEMV--NLYNGTPITAKSDIWALGCLLYKLCFFTLPFGESQVA-----ICDGNFTIPDHSRYSHEMHCLIRYMLEPDPDSRPEIYQVACFAFKLSGKECPILNVNGLSLPNKLP</Hsp_qseq>
      <Hsp_hseq>MLFEYVSGGQLLDYIIQHGS--IREHQARKFARGIASALIYLHANN--IVHRDLKIENIMISDSSEIKIIDF-------------GLSNIYDSRKQLHTFCGSLYFAAPELLKANPYTGPEV----DVWSFGVVLFVLVCGKVPFDDENSSVLHEKIKQGKVEYPQH--LSIEVISLLSKMLVVDPKRRATLKQVVEHHWMVRGFNGPPPSY----LPKRVP</Hsp_hseq>
      <Hsp_midline>+L E    GQ+++ + Q  S    E +  +       A+  LH     I+HRDLK+ENI++ D+    + DF             G+S + D  K+  T    L + APE++  N Y G  +    D+W+ G +L+ L    +PF +   +     I  G    P H   S E+  L+  ML  DP  R  + QV    + + G   P  +     LP ++P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>4.08893e-11</Hsp_evalue>
      <Hsp_query-from>127</Hsp_query-from>
      <Hsp_query-to>798</Hsp_query-to>
      <Hsp_hit-from>9</Hsp_hit-from>
      <Hsp_hit-to>236</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>246</Hsp_align-len>
      <Hsp_qseq>HQVTVEEVLAEGGFAIVFLVKTSGGVRSALKRMYVNNEHDLKVCQREITI----MKELSGHKNIVGYLDSSINA------QTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYT-----------TLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPF-GESQV</Hsp_qseq>
      <Hsp_hseq>HDFIFKEELGHGSYSTVF---------KALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLL-HKMGT-FNDIWTRHFTAQLIDALEFIHSHG--IIHRDLKPENVLLDRDGRLMITDFGAAA--TIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELL-LYNQ--CGYGSDIWALGCMIYQFVQGQPPFRGENEL</Hsp_hseq>
      <Hsp_midline>H    +E L  G ++ VF          AL +   N  + +KVC ++  I    +K ++  KN +  L    +A       T      +  +++    G++++ +  ++ T F +           +A+  +H     IIHRDLK EN+LL  +G  ++ DFG+A    ++P   G SA  +     +           T  Y +PE++ LYN       SDIWALGC++Y+      PF GE+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>5.00875e-11</Hsp_evalue>
      <Hsp_query-from>421</Hsp_query-from>
      <Hsp_query-to>783</Hsp_query-to>
      <Hsp_hit-from>1198</Hsp_hit-from>
      <Hsp_hit-to>1304</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>123</Hsp_align-len>
      <Hsp_qseq>LSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMV--NLYNGTPITAKSDIWALGCLLYKLCFFTLPF</Hsp_qseq>
      <Hsp_hseq>FKTNMTEFEAKLIFKQVVAGIKHLHDQG--IVHRDIKDENVIVDSKGFVKIIDFGSA--------AYVKSGPFDVF--VGTIDYAAPEVLGGNPYEGQP----QDIWAIGILLYTVVFKENPF</Hsp_hseq>
      <Hsp_midline>  T  TE E   IF      +  LH     I+HRD+K EN+++   G   + DFGSA        A+  S   D      T+ Y APE++  N Y G P     DIWA+G LLY + F   PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>5.83921e-11</Hsp_evalue>
      <Hsp_query-from>121</Hsp_query-from>
      <Hsp_query-to>783</Hsp_query-to>
      <Hsp_hit-from>408</Hsp_hit-from>
      <Hsp_hit-to>612</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>228</Hsp_align-len>
      <Hsp_qseq>GRHQVTVEEVLAEGGFAIVFLVKTSGGVRS------ALKRMYVNNEHDLKVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKY-TTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPF</Hsp_qseq>
      <Hsp_hseq>GPQDFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVG-LKFSFQTPT-----DLYLVTDYMSGGELFWHLQKE--GRFSEDRAKFYIAELVLALEHLHDND--IVYRDLKPENILLDANGNIALCDFGLSK-----------ADLKDRTNTFCGTTEYLAPEL--LLDETGYTKMVDFWSLGVLIFEMCCGWSPF</Hsp_hseq>
      <Hsp_midline>G     V  +L +G F  V+ VK     R       + K +   NE    + +R I +         IVG L  S    T     ++ ++ +    G++   + +     F+E        +   A+  LH     I++RDLK ENILL  NGN  LCDFG +            + ++D    +  T  Y APE+  L + T  T   D W+LG L++++C    PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>8.21871e-11</Hsp_evalue>
      <Hsp_query-from>259</Hsp_query-from>
      <Hsp_query-to>918</Hsp_query-to>
      <Hsp_hit-from>502</Hsp_hit-from>
      <Hsp_hit-to>706</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>229</Hsp_align-len>
      <Hsp_qseq>QREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFG-----SATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLP---FGESQVAICDGNFTIPD-HSRYSHEMHCLIRYMLEPDPDSRPEIYQV</Hsp_qseq>
      <Hsp_hseq>QHEMNLLKELH-HENIVTYYGASQEGGN------LNIFLEYVPGGSVSSMLNNY--GPFEESLITNFTRQILIGVAYLH--KKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSV----------FWMSPEVV---KQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKIGTNTTPEIPSWATSEGKNFLRKAFELDYQYRPSALEL</Hsp_hseq>
      <Hsp_midline>Q E+ ++KEL  H+NIV Y  +S           + I +E    G V + +N      F E  +          VA LH  K  IIHRD+K  NIL+   G   + DFG     S  NK  N +A    +V           + +PE+V     T  TAK+DIW+ GC++ ++     P   F + Q     G  T P+  S  + E    +R   E D   RP   ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>9.22085e-11</Hsp_evalue>
      <Hsp_query-from>151</Hsp_query-from>
      <Hsp_query-to>927</Hsp_query-to>
      <Hsp_hit-from>189</Hsp_hit-from>
      <Hsp_hit-to>414</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>262</Hsp_align-len>
      <Hsp_qseq>LAEGGFAIVFLVKTSGGVR-SALKRMYVNNEHD-LKVCQ-REITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPFGESQVAICDGNFTIPDHSRYSHEMHCLIRYMLEPDPDSRPEIYQVACF</Hsp_qseq>
      <Hsp_hseq>VGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFD-HPNVSTIKEIMVESQKT-----VYMIFEYADNDLSGLLLNKEVQISHSQCKHL--FKQLLLGMEYLHDNK--ILHRDVKGSNILIDNQGNLKITDFGLA--RKMNSRA-------DYTNRVITLWYRPPEL--LLGTTNYGTEVDMWGCGCLLVELF--------NKTAIFQGSNEL-------EQIESIFKIMGTPTINSWPTLYDMPWF</Hsp_hseq>
      <Hsp_midline>+ EG +  V+  K +   +  ALK++ +  E +   +   REI +++    H N+    +  + +Q +     V ++ E          +N+ +    ++C+ L  F      +  LH  K  I+HRD+K  NIL+ + GN  + DFG A  + +N +A       D   +  TL YR PE+  L   T    + D+W  GCLL +L         ++ AI  G+  +        ++  + + M  P  +S P +Y +  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>1.26061e-10</Hsp_evalue>
      <Hsp_query-from>124</Hsp_query-from>
      <Hsp_query-to>918</Hsp_query-to>
      <Hsp_hit-from>211</Hsp_hit-from>
      <Hsp_hit-to>475</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>290</Hsp_align-len>
      <Hsp_qseq>RHQVTVEEVLAEGGFAIVFLVKTSGGVRS-ALKRMYVNNEHDLKVCQREITIMKELSGHKN-----IVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVAR----LHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPFGESQVA-----------ICDGNFTIPDHSR----YSHEMHCLIRYMLEPDPDSRPEIYQV</Hsp_qseq>
      <Hsp_hseq>KDEITTLGILGEGAGGSVAKCRLKNGKKVFALKTINTMNTD----PEYQKQIFRELQFNKSFKSDYIVQYYGMFTDEQSSS----IYIAMEYMGGKSLEATYKNLLKRGGRISE--RVIGKIAESVLRGLSYLHERK--VIHRDIKPQNILLNEKGEIKLCDFG-VSGEAVNSLAMTFTG---------TSFYMAPERI---QGQPYSVTCDVWSLGLTLLEVAGGRFPFESDKITQNVAPIELLTMILTFSPQLKDEPELDISWSKTFRSFIDYCLKKDARERPSPRQM</Hsp_hseq>
      <Hsp_midline>+ ++T   +L EG    V   +   G +  ALK +   N       + +  I +EL  +K+     IV Y     + Q+SS    + I ME      +       L  G    E  R+     E+V R    LH+ K  +IHRD+K +NILL++ G   LCDFG  + + +N  A   +          T  Y APE +    G P +   D+W+LG  L ++     PF   ++            I   +  + D       +S      I Y L+ D   RP   Q+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>1.84051e-10</Hsp_evalue>
      <Hsp_query-from>454</Hsp_query-from>
      <Hsp_query-to>918</Hsp_query-to>
      <Hsp_hit-from>324</Hsp_hit-from>
      <Hsp_hit-to>482</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>175</Hsp_align-len>
      <Hsp_qseq>RIFCDTCEAVAR----LHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLS-YRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPFGESQVAICDGNFTI--------------PDHS-RYSHEMHCLIRYMLEPDPDSRPEIYQV</Hsp_qseq>
      <Hsp_hseq>KVLGKIAEAVLRGLSYLHEKK--VIHRDIKPQNILLNENGQVKLCDFGVSG-----------EAVNSLATTFTGTSFYMAPERI---QGQPYSVTSDVWSLGLTILEVANGKFPCSSEKMAANIAPFELLMWILTFTPELKDEPESNIIWSPSFKSFIDYCLKKDSRERPSPRQM</Hsp_hseq>
      <Hsp_midline>++     EAV R    LH+ K  +IHRD+K +NILL++NG   LCDFG +             AV      +T  S Y APE +    G P +  SD+W+LG  + ++     P    ++A     F +              P+ +  +S      I Y L+ D   RP   Q+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>2.4345e-10</Hsp_evalue>
      <Hsp_query-from>154</Hsp_query-from>
      <Hsp_query-to>783</Hsp_query-to>
      <Hsp_hit-from>630</Hsp_hit-from>
      <Hsp_hit-to>814</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>215</Hsp_align-len>
      <Hsp_qseq>AEGGFAIVFLVKTSGGVRSALKRMYVNNEHDLKVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFG--SATNKILNPQAHGVSAVEDEIKKYT---TLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPF</Hsp_qseq>
      <Hsp_hseq>ASGGVYTAYEIGTNVSV--AIKQMNLEKQPKKELIINEILVMKG-SKHPNIVNFIDSYV---LKGDLW---VIMEYMEGGSLTDVVTHCI---LTEGQIGAVCRETLSGLEFLHSKG--VLHRDIKSDNILLSMEGDIKLTDFGFCAQINEL-------------NLKRTTMVGTPYWMAPEVVSRKEYGP---KVDIWSLGIMIIEMIEGEPPY</Hsp_hseq>
      <Hsp_midline>A GG    + + T+  V  A+K+M +  +   ++   EI +MK  S H NIV ++DS +       +W   ++ME    G + + +   +    TE ++  +  +T   +  LH     ++HRD+K +NILL   G+  L DFG  +  N++              +K+ T   T  + APE+V+     P   K DIW+LG ++ ++     P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>2.59841e-10</Hsp_evalue>
      <Hsp_query-from>148</Hsp_query-from>
      <Hsp_query-to>1032</Hsp_query-to>
      <Hsp_hit-from>329</Hsp_hit-from>
      <Hsp_hit-to>649</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>86</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>54</Hsp_gaps>
      <Hsp_align-len>335</Hsp_align-len>
      <Hsp_qseq>VLAEGGFAIVFLVKTSGGVRSALKRMYVNNEHDL---KVCQREITIMKEL--SGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDF-------GSATNKILNPQAHGVSAVEDEIKKYT---TLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPF-----GESQVAICDGNFTIPDHSRYSHEMHCLIRYMLEPDPD------------SRPEIYQVACFAFKLSGKECPI---LNVNGLSLP-----NKLPEPLKASEAAAR</Hsp_qseq>
      <Hsp_hseq>LLGQGDVGKVYLVRERDT--NQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPFIVTLYHS---FQTKDYLY---LCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLG--FIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVI---RGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKFPHDKEVSKNCKDLIKKLLNKNEAKRLGSKSGAADIKRHPFFKKVQWSF-LRNQDPPLIPALNDNGCELPFILSCNKHPKRNSVSEQETK</Hsp_hseq>
      <Hsp_midline>+L +G    V+LV+      + +  + V N+H++   K  +R +T  + L  S H  IV    S    QT   ++   + ME C  G+    +  R S    E +      +   A+  LH      I+RDLK ENILLH +G+ +L DF       GS    + +          D  +  +   T  Y APE++    G   TA  D W LG L+Y++ F   PF      E+   I   +   P     S     LI+ +L  +               R   ++   ++F L  ++ P+   LN NG  LP     NK P+    SE   +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>2.62224e-10</Hsp_evalue>
      <Hsp_query-from>214</Hsp_query-from>
      <Hsp_query-to>789</Hsp_query-to>
      <Hsp_hit-from>82</Hsp_hit-from>
      <Hsp_hit-to>254</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>198</Hsp_align-len>
      <Hsp_qseq>LKRMYVNNEHDLKV-CQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVN--QMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLS--YRAPEMVNLYNGTPITA-KSDIWALGCLLYKLCFFTLPFGE</Hsp_qseq>
      <Hsp_hseq>IKRDSISNDYRKEVKIYREINALKHLS-HPNIVKLEEVLQNSRY------IGIVLEYACGGEFYKYIQKKRRLK----EMNACRLFSQLISGVHYIHSKG--LVHRDLKLENLLLDKNENLVITDFG-FVNEFCS---------RNELMKTSCGSPCYAAPELV--ISAEPYEARKADIWSCGVILYAILAGYLPWDD</Hsp_hseq>
      <Hsp_midline>+KR  ++N++  +V   REI  +K LS H NIV   +   N++       + I++E    G+     Q  +RL     E    R+F      V  +H     ++HRDLK+EN+LL  N N V+ DFG   N+  +          +E+ K +  S  Y APE+V   +  P  A K+DIW+ G +LY +    LP+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>8.74408e-10</Hsp_evalue>
      <Hsp_query-from>361</Hsp_query-from>
      <Hsp_query-to>948</Hsp_query-to>
      <Hsp_hit-from>177</Hsp_hit-from>
      <Hsp_hit-to>359</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>205</Hsp_align-len>
      <Hsp_qseq>VLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNL--YNGTPITAKSDIWALGCLLYKLCFFTLPFGE-------SQVAICDGNFTIPDHSRYSHEMHCLIRYMLEPDPDSRPEIYQVACFAFKLSGK</Hsp_qseq>
      <Hsp_hseq>VYLLMEYLVNGEMYKLL--RLHGPFNDILASDYIYQIANALDYMH--KKNIIHRDIKPENILIGFNNVIKLTDFGWS---IINPPENRRKTV------CGTIDYLSPEMVESREYDHT-----IDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALD--IKMP--SNISQDAQDLILKLLKYDPKDRMRLGDVKMHPWILRNK</Hsp_hseq>
      <Hsp_midline>V +LME    G++   +  RL   F +            A+  +H  K  IIHRD+K ENIL+  N    L DFG +   I+NP  +    V        T+ Y +PEMV    Y+ T      D WALG L ++L     PF E        ++A  D    +P  S  S +   LI  +L+ DP  R  +  V    + L  K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>1.12645e-09</Hsp_evalue>
      <Hsp_query-from>148</Hsp_query-from>
      <Hsp_query-to>792</Hsp_query-to>
      <Hsp_hit-from>92</Hsp_hit-from>
      <Hsp_hit-to>285</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>222</Hsp_align-len>
      <Hsp_qseq>VLAEGGFAIVFLVKTSGGVRSALKRMYVNNEHDLKVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVW-------EVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPFGES</Hsp_qseq>
      <Hsp_hseq>TLGTGSFGRVHLIRSRHNGRY----------YAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLL--RKSQRFPNPVAKFYAAEVCLALEYLHSKD--IIYRDLKPENILLDKNGHIKITDFGFA--KYVPDVTYTLCGTPD---------YIAPEVVST---KPYNKSIDWWSFGILIYEMLAGYTPFYDS</Hsp_hseq>
      <Hsp_midline> L  G F  V L+++    R           + +KV ++EI +  +   H N    + S +       +W       ++ ++M+    G++ + +  R S  F          + C A+  LH     II+RDLK ENILL  NG+  + DFG A  K +    + +    D         Y APE+V+     P     D W+ G L+Y++     PF +S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>1.22797e-09</Hsp_evalue>
      <Hsp_query-from>151</Hsp_query-from>
      <Hsp_query-to>768</Hsp_query-to>
      <Hsp_hit-from>8</Hsp_hit-from>
      <Hsp_hit-to>217</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>56</Hsp_gaps>
      <Hsp_align-len>236</Hsp_align-len>
      <Hsp_qseq>LAEGGFAIVFLVKTSGGVRSALKRM---YVNNEHDLKVCQREITIMKELSG---HKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTG------FTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVN------------------LYNGTPITAKSDIWALGCLLYKLCF</Hsp_qseq>
      <Hsp_hseq>IQSGTFSTVYKAWSTTHNRYVALKITPKYKTSEANMK---NEYDVMKILSSCNPHPNICSMLDFYTDDSY------YIMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQIDMQKIIKQLCSAISFAHSLG--IAHRDIKPENILLTINGDIKLADWGHA---IQSPKSNDFQIGTD--------NYRAPETFSGRVSNSCFKKNFDRSSAPLYN----TYQADYWSLGATIFYLMF</Hsp_hseq>
      <Hsp_midline>+  G F+ V+   ++   R    ++   Y  +E ++K    E  +MK LS    H NI   LD   +          ++++E C  G + + ++   S G        + ++ +I    C A++  H     I HRD+K ENILL  NG+  L D+G A   I +P+++      D        +YRAPE  +                  LYN    T ++D W+LG  ++ L F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>1.395e-09</Hsp_evalue>
      <Hsp_query-from>148</Hsp_query-from>
      <Hsp_query-to>789</Hsp_query-to>
      <Hsp_hit-from>51</Hsp_hit-from>
      <Hsp_hit-to>254</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>228</Hsp_align-len>
      <Hsp_qseq>VLAEGGFAIVFLVKTSGGVRSA---------LKRMYVNNEHDLKV-CQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVN--QMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLS--YRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPFGE</Hsp_qseq>
      <Hsp_hseq>TLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLT-HPNII-YLEEVLQNSKYIG-----IVLEFVSGGEFYKYIQRKRRLK----ESSACRLFAQLISGVNYMHYKG--LVHRDLKLENLLLDKHENLVITDFG-FVNEFFE---------DNELMKTSCGSPCYAAPELV-VSTKAYEARKADVWSCGVILYAMLAGYLPWDD</Hsp_hseq>
      <Hsp_midline> L EG F  V L  T     +          ++R  +  + D ++   REI  +K L+ H NI+ YL+  +      G     I++E    G+     Q  +RL     E    R+F      V  +H     ++HRDLK+EN+LL  + N V+ DFG   N+            ++E+ K +  S  Y APE+V +        K+D+W+ G +LY +    LP+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>2.35725e-09</Hsp_evalue>
      <Hsp_query-from>262</Hsp_query-from>
      <Hsp_query-to>762</Hsp_query-to>
      <Hsp_hit-from>58</Hsp_hit-from>
      <Hsp_hit-to>216</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>REITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFC-DTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYT----TLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKL</Hsp_qseq>
      <Hsp_hseq>REIKILKHFK-HENIITIFNIQ-RPDSFENFNEVYIIQELMQT-----DLHRVISTQMLSDDHIQYFIYQTLRAVKVLHGSN--VIHRDLKPSNLLINSNCDLKVCDFGLA--RIIDESAADNSEPTGQQSGMTEYVATRWYRAPEV--MLTSAKYSRAMDVWSCGCILAEL</Hsp_hseq>
      <Hsp_midline>REI I+K    H+NI+   +      +     EV I+ E+ +       +++ +ST     + ++ F   T  AV  LH     +IHRDLK  N+L++ N +  +CDFG A  +I++  A   S    +    T    T  YRAPE+  +      +   D+W+ GC+L +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>2.38422e-09</Hsp_evalue>
      <Hsp_query-from>130</Hsp_query-from>
      <Hsp_query-to>795</Hsp_query-to>
      <Hsp_hit-from>6</Hsp_hit-from>
      <Hsp_hit-to>208</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>226</Hsp_align-len>
      <Hsp_qseq>QVTVEEVLAEGGFAIVFL-VKTSGGVRSALKRMYVNNEHD-LKVCQ-REITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLIL-MEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPFGESQ</Hsp_qseq>
      <Hsp_hseq>EYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQ-HPNVIELIDIFMAYDNLNLVLEFLPTDLEVVIKDK---------SILFTPADIKAWMLMTLRGVYHCH--RNFILHRDLKPNNLLFSPDGQIKVADFGLA-RAIPAPHEILTSNV-------VTRWYRAPEL--LFGAKHYTSAIDIWSVGVIFAEL-MLRIPYLPGQ</Hsp_hseq>
      <Hsp_midline>+ T E+ + EG +A+V+L  + S G + A+K +  +   D L +   RE+  ++E+  H N++  +D  +     + V E L   +E+    +         S  FT  ++      T   V   H  +  I+HRDLK  N+L   +G   + DFG A   I  P     S V        T  YRAPE+  L+     T+  DIW++G +  +L    +P+   Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>2.66702e-09</Hsp_evalue>
      <Hsp_query-from>229</Hsp_query-from>
      <Hsp_query-to>933</Hsp_query-to>
      <Hsp_hit-from>49</Hsp_hit-from>
      <Hsp_hit-to>271</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>249</Hsp_align-len>
      <Hsp_qseq>VNNEH---DLKVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYT---TLSYRAPEM----VNLYNGTPITAKSDIWALGCLLYKLCFFTLPFGESQVAICDGNFTIPDHSR----YSHEMHCLIRYMLEPDPDSRPEIYQVACFAF</Hsp_qseq>
      <Hsp_hseq>VNLEHSDEDIELLAQEIFFLAELKSPL-ITNYIATMLE---DVSMW---IVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRK--IHRDIKAANILLNEEGMVKLGDFGVSGH------------IRSTLKRDTFVGTPYWMAPEVVCCEVDGYN-----EKADIWSLGITTYELLKGLPPLSKYDPMKVMTNLPKRKPPKLQGPFSDAAKDFVAGCLVKTPADRPSAYNLLSFEF</Hsp_hseq>
      <Hsp_midline>VN EH   D+++  +EI  + EL     I  Y+ + +       +W   I+ME C  G   + + +    G  E +V  I  +    +  LH+ +   IHRD+K  NILL++ G   L DFG + +            +   +K+ T   T  + APE+    V+ YN      K+DIW+LG   Y+L     P  +        N       +    +S      +   L   P  RP  Y +  F F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>3.66012e-09</Hsp_evalue>
      <Hsp_query-from>262</Hsp_query-from>
      <Hsp_query-to>783</Hsp_query-to>
      <Hsp_hit-from>103</Hsp_hit-from>
      <Hsp_hit-to>276</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>183</Hsp_align-len>
      <Hsp_qseq>REITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVV----NQMNQRL--STGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTL---SYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPF</Hsp_qseq>
      <Hsp_hseq>QEIEVMKRCH-HENVVE-LYEILNDPESTKVY---LVLEYCSRGPVKWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHS--QGITHRDIKPSNLLISSNGTVKISDFGVAMSTATG--STNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPF</Hsp_hseq>
      <Hsp_midline>+EI +MK    H+N+V  L   +N   S+ V+   +++E C  G V     N+M  +    +  T  +  ++  D    +  LH     I HRD+K  N+L+  NG   + DFG A +      +  + +  +++ K   L   ++ APE+ +       ++  DIW+LG  +Y L F  LPF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>3.75e-09</Hsp_evalue>
      <Hsp_query-from>361</Hsp_query-from>
      <Hsp_query-to>879</Hsp_query-to>
      <Hsp_hit-from>569</Hsp_hit-from>
      <Hsp_hit-to>754</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>196</Hsp_align-len>
      <Hsp_qseq>VLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDF---------------GSATNKILNPQAHGVSAVEDEIKKYT---TLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPF-----GESQVAICDGNFTIPDHSRYSHEMHCLIRYML</Hsp_qseq>
      <Hsp_hseq>LYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLG--FIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVD-----TKICSDGFRTNSFVGTEEYIAPEVI---RGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKNEVSFPNNNEISRTCKDLIKKLL</Hsp_hseq>
      <Hsp_midline>+ + ME C  G+    +  R +    E +      +   A+  LH      I+RDLK ENILLH +G+ +L DF               GSA + +++          D  +  +   T  Y APE++    G   TA  D W LG L+Y++ F   PF      E+   I     + P+++  S     LI+ +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>4.07178e-09</Hsp_evalue>
      <Hsp_query-from>112</Hsp_query-from>
      <Hsp_query-to>792</Hsp_query-to>
      <Hsp_hit-from>83</Hsp_hit-from>
      <Hsp_hit-to>286</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>230</Hsp_align-len>
      <Hsp_qseq>YAVGRHQVTVEEVLAEGGFAIVFLVKTS-GGVRSALKRMYVNNEHDLKVCQREITIMKELS--GHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPFGES</Hsp_qseq>
      <Hsp_hseq>YSLSDFQIL--RTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQ------QVFMVMDYIEGGELFSLL--RKSQRFPNPVAKFYAAEVCLALEYLHSKD--IIYRDLKPENILLDKNGHIKITDFGFA--KYVPDVTYTLCGTPD---------YIAPEVVST---KPYNKSVDWWSFGVLIYEMLAGYTPFYNS</Hsp_hseq>
      <Hsp_midline>Y++   Q+     L  G F  V L++++  G   ALK +  +    LK  +      + LS   H  I+    +  ++Q      +V ++M+    G++ + +  R S  F          + C A+  LH     II+RDLK ENILL  NG+  + DFG A  K +    + +    D         Y APE+V+     P     D W+ G L+Y++     PF  S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>4.61767e-09</Hsp_evalue>
      <Hsp_query-from>160</Hsp_query-from>
      <Hsp_query-to>786</Hsp_query-to>
      <Hsp_hit-from>1275</Hsp_hit-from>
      <Hsp_hit-to>1501</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>240</Hsp_align-len>
      <Hsp_qseq>GGFAIVF-LVKTSGGVRSALKRMYVNNEHDLK----VCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECE-VLRIFC-DTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSAT------------NKILNPQA--HGVSAVEDE----------IKKYTTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPFG</Hsp_qseq>
      <Hsp_hseq>GTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVL-EILNHPNIVSYYGVEVHRD------KVNIFMEYCEGGSLA----ALLEHGRIEDEMVTQVYTLQLLEGLAYLHE--SGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPWA</Hsp_hseq>
      <Hsp_midline>G F  V+  V    G   A+K + + +   ++    + + E++++ E+  H NIV Y    ++        +V I ME C  G +       L  G  E E V +++     E +A LH+  + I+HRD+K ENILL  NG     DFG+A             NKI N       V+ V D           +    T  Y APE +            D+W+LGC++ ++     P+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>5.34763e-09</Hsp_evalue>
      <Hsp_query-from>151</Hsp_query-from>
      <Hsp_query-to>909</Hsp_query-to>
      <Hsp_hit-from>206</Hsp_hit-from>
      <Hsp_hit-to>471</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>118</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>275</Hsp_align-len>
      <Hsp_qseq>LAEGGFAIVFLVKTSG-GVRSALKRMYVNNEHDLKVCQ--REITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLH--DNGNYVLCDFGSATNKILNPQAH----GVSAVEDEIKKYTTL----SYRAPEMVNLYNGTPITAKSDIWALGCLLYK-LCFFTLPFGES--------QVAICDGNFTIPDHSRYSHEMHCLIRYMLEPDPDSRPEI</Hsp_qseq>
      <Hsp_hseq>LGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKI-DDGELFERIVRK--TCLRQDESKALFKQLLTGLKYLHEQN--IIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVL---TKKGYTSKVDLWSAGVILYVCLCGFP-PFSDQLGPPSLKEQILQAKYAFYSPYWDKIDDSVLHLISNLLVLNPDERYNI</Hsp_hseq>
      <Hsp_midline>L  G +A+V   K    G + A+K  +     D K  +  RE T +     H NIV  LDS +   + S + + L+L +I   G++  ++ ++  T   + E   +F      +  LH+    IIHRD+K ENILL+     N      G      ++ Q      G++    E++   TL    SY APE++        T+K D+W+ G +LY  LC F  PF +         Q+      F  P   +    +  LI  +L  +PD R  I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YDL028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:400997:403291:-1 gene:YDL028C transcript:YDL028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MPS1 description:Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]</Hit_def>
  <Hit_accession>YDL028C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>5.47376e-09</Hsp_evalue>
      <Hsp_query-from>109</Hsp_query-from>
      <Hsp_query-to>933</Hsp_query-to>
      <Hsp_hit-from>432</Hsp_hit-from>
      <Hsp_hit-to>715</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>43</Hsp_gaps>
      <Hsp_align-len>301</Hsp_align-len>
      <Hsp_qseq>VYAVGRHQVTVEEVLAEGGFAIVFLVKTSGGVRSALKRMYVN--NEHDLKVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFC-DTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNGT------------PITAKSDIWALGCLLYKLCFFTLPFGESQ-----VAICDGNFTI--PDHSRYSHEMHC----LIRYMLEPDPDSRPEIYQVACFAF</Hsp_qseq>
      <Hsp_hseq>IITVNDSQYEKIELLGRGGSSRVYKVKGSGNRVYALKRVSFDAFDDSSIDGFKGEIELLEKLKDQKRVIQLLDYEM------GDGLLYLIME-CGDHDLSQILNQRSGMPL-DFNFVRFYTKEMLLCIKVVHDAG--IVHSDLKPANFVLV-KGILKIIDFGIA-NAV--PE-HTVNIYRE--TQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYGKPPYGSFQGQNRLLAIMNPDVKIPFPEHTSNNEKIPKSAIELMKACLYRNPDKRWTVDKVLSSTF</Hsp_hseq>
      <Hsp_midline>+  V   Q    E+L  GG + V+ VK SG    ALKR+  +  ++  +   + EI ++++L   K ++  LD  +      G   + ++ME C    +   +NQR      +   +R +  +    +  +H     I+H DLK  N +L   G   + DFG A N +  P+ H V+   +   +  T +Y APE +   N T             +   SD+W+ GC++Y++ +   P+G  Q     +AI + +  I  P+H+  + ++      L++  L  +PD R  + +V    F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>1.04e-08</Hsp_evalue>
      <Hsp_query-from>367</Hsp_query-from>
      <Hsp_query-to>900</Hsp_query-to>
      <Hsp_hit-from>200</Hsp_hit-from>
      <Hsp_hit-to>365</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>188</Hsp_align-len>
      <Hsp_qseq>ILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTT----LSYRAPEMVNLYNGTPITAKS-DIWALGCLLYKLCFFTLPFGESQVAIC-----DGNFTIPDHSRYSHEMHCLIRYMLEPDPDSR</Hsp_qseq>
      <Hsp_hseq>MLFEYVSGGQLLDYIIQHGS--LKEHHARKFARGIASALQYLHANN--IVHRDLKIENIMISSSGEIKIIDF-------------GLSNIFDYRKQLHTFCGSLYFAAPE---LLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYPSH--LSIEVISLLTRMIVVDPLRR</Hsp_hseq>
      <Hsp_midline>+L E    GQ+++ + Q  S    E    +       A+  LH     I+HRDLK+ENI++  +G   + DF             G+S + D  K+  T    L + APE   L    P T    DIW+ G +LY L    +PF +   +I       G    P H   S E+  L+  M+  DP  R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>1.70049e-08</Hsp_evalue>
      <Hsp_query-from>136</Hsp_query-from>
      <Hsp_query-to>900</Hsp_query-to>
      <Hsp_hit-from>25</Hsp_hit-from>
      <Hsp_hit-to>313</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>127</Hsp_positive>
      <Hsp_gaps>62</Hsp_gaps>
      <Hsp_align-len>303</Hsp_align-len>
      <Hsp_qseq>TVEEVLAEGGFAIVFL--VKTSGGVRSALK---RMYVNNEHDLKVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQR---------LST-------------GFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILL-------HDNGNYVLCDFGSATN-KILNPQAHGVSAVEDEIKKYTTLS----YRAPEMVNL--YNGTPITAKSDIWALGCLLYKLCFFTLPFGES-------QVAICDGNFTIPDHSRYSHEMHCLIRYMLEPDPDSR</Hsp_qseq>
      <Hsp_hseq>TAEKEIGKGSFATVYRGHLTSDKSQHVAIKEVSRAKLKNKKLLENLEIEIAILKKIK-HPHIVGLIDCE---RTSTDFY---LIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKN--LVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYN-----AKADLWSVGTVVFEMCCGTPPFRASNHLELFKKIKRANDVITFPSYCNIEPELKELICSLLTFDPAQR</Hsp_hseq>
      <Hsp_midline>T E+ + +G FA V+   + +      A+K   R  + N+  L+  + EI I+K++  H +IVG +D     +TS+  +   ++ME C  G +   + +R         L T             G     VL        A+  L      ++HRD+K +N+LL       HD+ ++    F    N  IL     G +          TL     Y APE++N   YN     AK+D+W++G +++++C  T PF  S       ++   +   T P +     E+  LI  +L  DP  R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>3.40991e-08</Hsp_evalue>
      <Hsp_query-from>511</Hsp_query-from>
      <Hsp_query-to>762</Hsp_query-to>
      <Hsp_hit-from>140</Hsp_hit-from>
      <Hsp_hit-to>210</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>IIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKL</Hsp_qseq>
      <Hsp_hseq>VIHRDLKPSNILINENCDLKICDFGLA--RIQDPQMTGY---------VSTRYYRAPEIMLTWQKYDV--EVDIWSAGCIFAEM</Hsp_hseq>
      <Hsp_midline>+IHRDLK  NIL+++N +  +CDFG A  +I +PQ  G           +T  YRAPE++  +    +  + DIW+ GC+  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YAR018C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:170396:171703:-1 gene:YAR018C transcript:YAR018C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN3 description:Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol [Source:SGD;Acc:S000000071]</Hit_def>
  <Hit_accession>YAR018C</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>3.86262e-08</Hsp_evalue>
      <Hsp_query-from>124</Hsp_query-from>
      <Hsp_query-to>918</Hsp_query-to>
      <Hsp_hit-from>22</Hsp_hit-from>
      <Hsp_hit-to>337</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>137</Hsp_positive>
      <Hsp_gaps>77</Hsp_gaps>
      <Hsp_align-len>329</Hsp_align-len>
      <Hsp_qseq>RHQVTVEEVLAEGGFA----IVFLVKTSGGVRSALKRMYVNNEHDLKVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLIL-MEICRAG---QVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLH-------------QCKTPI------IHRDLKVENILL-HDNGNYVLC---------------DFGSATNKILNPQAHG-----------VSAVEDEIKKYTTL----SYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPFG-----ESQVAICDGN-FTIPDHSRYSHEMHCLIRYMLEPDPDSRPEIYQV</Hsp_qseq>
      <Hsp_hseq>RSEYQVLEEIGRGSFGSVRKVIHIPTKKLLVRKDIKYGHMNSKERQQLIA-ECSILSQLK-HENIVEFYNWDFDEQK-----EVLYLYMEYCSRGDLSQMIKHYKQE-HKYIPEKIVWGILAQLLTALYKCHYGVELPTLTTIYDRMKPPVKGKNIVIHRDLKPGNIFLSYDDSDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLAKSLETSIQFATTYVGTPYYMSPEVLM---DQPYSPLSDIWSLGCVIFEMCSLHPPFQAKNYLELQTKIKNGKCDTVPEY--YSRGLNAIIHSMIDVNLRTRPSTFEL</Hsp_hseq>
      <Hsp_midline>R +  V E +  G F     ++ +      VR  +K  ++N++   ++   E +I+ +L  H+NIV + +   + Q      EVL L ME C  G   Q++    Q       E  V  I      A+ + H             + K P+      IHRDLK  NI L +D+ +Y +                D    + K  +P  +              ++E  I+  TT      Y +PE++      P +  SDIW+LGC+++++C    PF      E Q  I +G   T+P++  YS  ++ +I  M++ +  +RP  +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>7.22463e-08</Hsp_evalue>
      <Hsp_query-from>127</Hsp_query-from>
      <Hsp_query-to>792</Hsp_query-to>
      <Hsp_hit-from>68</Hsp_hit-from>
      <Hsp_hit-to>268</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>231</Hsp_align-len>
      <Hsp_qseq>HQVTVEEVLAEGGFAIVFLVKTSGGVR----SALKRMYVNNEHDLKVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYT-----TLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPFGES</Hsp_qseq>
      <Hsp_hseq>HDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLK-LVEHPFLIRMWGTFQDARN------IFMVMDYIEGGELFSLL--RKSQRFPNPVAKFYAAEVILALEYLHAHN--IIYRDLKPENILLDRNGHIKITDFGFAK----------------EVQTVTWTLCGTPDYIAPEVITT---KPYNKSVDWWSLGVLIYEMLAGYTPFYDT</Hsp_hseq>
      <Hsp_midline>H   +   L  G F  V LV++    R      LK+  V     ++    E  ++K L  H  ++    +  +A+       + ++M+    G++ + +  R S  F          +   A+  LH     II+RDLK ENILL  NG+  + DFG A                 E++  T     T  Y APE++      P     D W+LG L+Y++     PF ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YHR079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:258244:261591:-1 gene:YHR079C transcript:YHR079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IRE1 description:Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; role in homeostatic adaptation to ER stress; Kar2p binds inactive Ire1p and releases from it upon ER stress [Source:SGD;Acc:S000001121]</Hit_def>
  <Hit_accession>YHR079C</Hit_accession>
  <Hit_len>1115</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>8.40357e-08</Hsp_evalue>
      <Hsp_query-from>124</Hsp_query-from>
      <Hsp_query-to>918</Hsp_query-to>
      <Hsp_hit-from>671</Hsp_hit-from>
      <Hsp_hit-to>974</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>125</Hsp_positive>
      <Hsp_gaps>67</Hsp_gaps>
      <Hsp_align-len>318</Hsp_align-len>
      <Hsp_qseq>RHQVTVEEVLAEGGFAIVFLVKTSGGVRSALKRMYVNNEHDLKVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEV--LILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNY-------------VLCDFGSATNKILNPQAHGVSAVEDEIKKYT-TLSYRAPEMVNLYNG-----------------------TPITAKS-----DIWALGCLLYK-LCFFTLPFGES---QVAICDGNFTIPD----HSR-YSHEMHCLIRYMLEPDPDSRPEIYQV</Hsp_qseq>
      <Hsp_hseq>KNLVVSEKILGYGSSGTVVFQGSFQGRPVAVKRMLIDF---CDIALMEIKLLTESDDHPNVIRYYCSETTDRFLYIALELCNLNLQDLVESKNVSDE-NLKLQKEYNPISLLR---QIASGVAHLHSLK--IIHRDLKPQNILVSTSSRFTADQQTGAENLRILISDFG-----LCKKLDSGQSSFRTNLNNPSGTSGWRAPELLEESNNLQCQVETEHSSSRHTVVSSDSFYDPFTKRRLTRSIDIFSMGCVFYYILSKGKHPFGDKYSRESNIIRGIFSLDEMKCLHDRSLIAEATDLISQMIDHDPLKRPTAMKV</Hsp_hseq>
      <Hsp_midline>++ V  E++L  G    V    +  G   A+KRM ++      +   EI ++ E   H N++ Y  S    +      E+  L L ++  +  V ++ N +L   +    +LR        VA LH  K  IIHRDLK +NIL+  +  +             ++ DFG     +      G S+    +   + T  +RAPE++   N                         P T +      DI+++GC+ Y  L     PFG+    +  I  G F++ +    H R    E   LI  M++ DP  RP   +V</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YDL079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:312951:314748:-1 gene:YDL079C transcript:YDL079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRK1 description:Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication [Source:SGD;Acc:S000002237]</Hit_def>
  <Hit_accession>YDL079C</Hit_accession>
  <Hit_len>501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>9.97014e-08</Hsp_evalue>
      <Hsp_query-from>145</Hsp_query-from>
      <Hsp_query-to>798</Hsp_query-to>
      <Hsp_hit-from>168</Hsp_hit-from>
      <Hsp_hit-to>371</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>230</Hsp_align-len>
      <Hsp_qseq>EVLAEGGFAIVF---LVKTSGGVRSALKRMYVNNEHDLKVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEIC-----RAGQVVNQMNQ--RLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNG-NYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPF-GESQV</Hsp_qseq>
      <Hsp_hseq>EVVGHGSFGVVVTTVIIETNQKV--AIKKVL----QDRRYKNRELETMKMLC-HPNTVGLQYYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFK-------ALNYLHNVPR-ICHRDIKPQNLLVDPTTFSFKICDFGSA--KCLKPDQPNVSYI-------CSRYYRAPEL--MFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGI</Hsp_hseq>
      <Hsp_midline>EV+  G F +V    +++T+  V  A+K++      D +   RE+  MK L  H N VG             V+  L+L  +      R    VN   Q  R+   F   ++ +       A+  LH     I HRD+K +N+L+     ++ +CDFGSA  K L P    VS +        +  YRAPE+  ++  T  + + D+W+  C++ +L      F GES +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>1.89777e-07</Hsp_evalue>
      <Hsp_query-from>478</Hsp_query-from>
      <Hsp_query-to>900</Hsp_query-to>
      <Hsp_hit-from>457</Hsp_hit-from>
      <Hsp_hit-to>587</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>149</Hsp_align-len>
      <Hsp_qseq>AVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYT---TLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPFGESQVA-----ICDGNFTIPDHSRYSHEMHCLIRYMLEPDPDSR</Hsp_qseq>
      <Hsp_hseq>ALDNLH--KLDVVYRDLKPENILLDYQGHIALCDFGLCK---LN--------MKDDDKTDTFCGTPEYLAPELL---LGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDG--FDRDAKDLLIGLLSRDPTRR</Hsp_hseq>
      <Hsp_midline>A+  LH  K  +++RDLK ENILL   G+  LCDFG      LN        ++D+ K  T   T  Y APE++    G   T   D W LG LLY++     P+ +  V      I       PD   +  +   L+  +L  DP  R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>1.91168e-07</Hsp_evalue>
      <Hsp_query-from>406</Hsp_query-from>
      <Hsp_query-to>804</Hsp_query-to>
      <Hsp_hit-from>434</Hsp_hit-from>
      <Hsp_hit-to>549</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>QMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYT---TLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPFGESQVAI</Hsp_qseq>
      <Hsp_hseq>QHEGRFSLARSRFYIAELLC----ALDSLH--KLDVIYRDLKPENILLDYQGHIALCDFGLCK---LN--------MKDNDKTDTFCGTPEYLAPEIL---LGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPV</Hsp_hseq>
      <Hsp_midline>Q   R S   +   +  + C    A+  LH  K  +I+RDLK ENILL   G+  LCDFG      LN        ++D  K  T   T  Y APE++    G   T   D W LG LLY++     P+ +  V +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>2.21718e-07</Hsp_evalue>
      <Hsp_query-from>259</Hsp_query-from>
      <Hsp_query-to>783</Hsp_query-to>
      <Hsp_hit-from>190</Hsp_hit-from>
      <Hsp_hit-to>379</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>197</Hsp_align-len>
      <Hsp_qseq>QREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVV------NQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGS--ATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEM--------------VNLYNGTPITAKSDIWALGCLLYKLCFFTLPF</Hsp_qseq>
      <Hsp_hseq>KREIAIMKKCH-HKHVVQLIEVLDDLKS----RKIYLVLEYCSRGEVKWCPPDCMESDAKGPSLLSFQETREILRGVVLGLEYLHYQG--IIHRDIKPANLLISGDGTVKISDFGVSLAASSTNSSDSSESLDELELAKTVGTPAFFAPEMCLGEDAFTRYNLTKENLFRGSCISFMIDIWAVGVTLYCLLFGMLPF</Hsp_hseq>
      <Hsp_midline>+REI IMK+   HK++V  ++   + ++     ++ +++E C  G+V        + + +  +  +  E   I       +  LH     IIHRD+K  N+L+  +G   + DFG   A +   +  +       +  K   T ++ APEM               NL+ G+ I+   DIWA+G  LY L F  LPF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>2.33117e-07</Hsp_evalue>
      <Hsp_query-from>130</Hsp_query-from>
      <Hsp_query-to>783</Hsp_query-to>
      <Hsp_hit-from>221</Hsp_hit-from>
      <Hsp_hit-to>445</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>55</Hsp_gaps>
      <Hsp_align-len>249</Hsp_align-len>
      <Hsp_qseq>QVTVEEVLAEGGFAIVFLVKTSGGVRSALKRMYVNNEHDLKVCQREITIMKELSGHKNIVGYL--DSSINAQTSSGVWEVLI-----------LMEICRAGQVVNQMNQRLSTGFTECEVL-RIFCDTCEAVARLHQCKTPIIHRDLKVENILLH---DNGNYV-------------LCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITAK-SDIWALGCLLYKLCFFTLPF</Hsp_qseq>
      <Hsp_hseq>QVAVKRLKYPEELSNVEQINTSLRYKETLSRL----ENSLT---RELQVLKSL-NHPCIVKLLGINNPIFVTSKKPLCDLIIKTPRALPPCDMIMSYCPAGDLLAAVMAR--NGRLEAWLIQRIFTEVVLAVKYLHENS--IIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLCKKIENNEMCTARCGSED---------YVSPEIL---MGVPYDGHLSDTWALGVILYSLFEDRLPF</Hsp_hseq>
      <Hsp_midline>QV V+ +      + V  + TS   +  L R+    E+ L    RE+ ++K L  H  IV  L  ++ I   +   + +++I           +M  C AG ++  +  R   G  E  ++ RIF +   AV  LH+    IIHRDLK+ENILL    D+ N               L DFG       N         ED         Y +PE++    G P     SD WALG +LY L    LPF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YKL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:347214:349136:-1 gene:YKL048C transcript:YKL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ELM1 description:Serine/threonine protein kinase; regulates the orientation checkpoint, the morphogenesis checkpoint and the metabolic switch from fermentative to oxidative metabolism by phosphorylating the activation loop of Kin4p, Hsl1p and Snf4p respectively; cooperates with Hsl7p in recruiting Hsl1p to the septin ring, a prerequisite for subsequent recruitment, phosphorylation, and degradation of Swe1p; forms part of the bud neck ring; regulates cytokinesis [Source:SGD;Acc:S000001531]</Hit_def>
  <Hit_accession>YKL048C</Hit_accession>
  <Hit_len>640</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>2.52865e-07</Hsp_evalue>
      <Hsp_query-from>100</Hsp_query-from>
      <Hsp_query-to>795</Hsp_query-to>
      <Hsp_hit-from>110</Hsp_hit-from>
      <Hsp_hit-to>359</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>266</Hsp_align-len>
      <Hsp_qseq>VGRVYAV--------GRHQVTVEEVLAEGGFAIVFLVKTSGGVRSALKRMYVNNEHDLKVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVV-------NQMNQRLSTGFTECEV----LRIFCDTCEAVARLHQ--CKTPIIHRDLKVENILLHDNGNYV-LCDFGSATNKILNPQAHGVSAV--ED----EIKKYT-TLSYRAPEMVNLYNGTP--ITA--KSDIWALGCLLYKLCFFTLP-FGESQ</Hsp_qseq>
      <Hsp_hseq>LGKVVAVKIIPKKPWNAQQYSVNQVMRQ-----IQLWKSKGKITTNMSGNEAMRLMNIEKCRWEIFAASRLRNNVHIVRLIEC-LDSPFSESIW---IVTNWCSLGELQWKRDDDEDILPQWKKIVISNCSVSTFAKKILEDMTKGLEYLHSQGC----IHRDIKPSNILLDEEEKVAKLSDFGSC---IFTPQSLPFSDANFEDCFQRELNKIVGTPAFIAPELCHLGNSKRDFVTDGFKLDIWSLGVTLYCLLYNELPFFGENE</Hsp_hseq>
      <Hsp_midline>+G+V AV           Q +V +V+ +     + L K+ G + + +         +++ C+ EI     L  + +IV  ++  +++  S  +W   I+   C  G++        + + Q      + C V     +I  D  + +  LH   C    IHRD+K  NILL +      L DFGS    I  PQ+   S    ED    E+ K   T ++ APE+ +L N     +T   K DIW+LG  LY L +  LP FGE++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>2.98215e-07</Hsp_evalue>
      <Hsp_query-from>511</Hsp_query-from>
      <Hsp_query-to>903</Hsp_query-to>
      <Hsp_hit-from>481</Hsp_hit-from>
      <Hsp_hit-to>612</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>IIHRDLKVENILLHDN-GNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNG--TPITAKSDIWALGCLLYKLCFFTLPFGE-------SQV-AICDGNFTIPDHSRYSHEMHCLIRYMLEPDPDSRP</Hsp_qseq>
      <Hsp_hseq>IIHRDVKPTNILCSANQGTVKLCDFGVSGNLV-------ASLAKTNIG---CQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYPPETYDNIFSQLSAIVDGPPPRLPSDKFSSDAQDFVSLCLQKIPERRP</Hsp_hseq>
      <Hsp_midline>IIHRD+K  NIL   N G   LCDFG + N +        S  +  I      SY APE +   N      T +SDIW+LG  + ++     P+         SQ+ AI DG        ++S +    +   L+  P+ RP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>3.32348e-07</Hsp_evalue>
      <Hsp_query-from>115</Hsp_query-from>
      <Hsp_query-to>900</Hsp_query-to>
      <Hsp_hit-from>813</Hsp_hit-from>
      <Hsp_hit-to>1066</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>281</Hsp_align-len>
      <Hsp_qseq>AVGRHQVTVE-----EVLAEGGFAIVFLVKTSGGVR----SALKRMYVNNEHDLKVCQREITIMKELSGHKNIVGYLDSSI-NAQTSSGVWEVLILMEICRAGQVV-NQMNQRLS---TGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPF-GESQVAICDGNFTIPDHSRYSHEMHCLI----RYMLEPDPDSR</Hsp_qseq>
      <Hsp_hseq>AAKRRKVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVF--LLATKTKHPFLTNLYCSFQTENRIY---FAMEFIGGGDLMWHVQNQRLSVRRAKFYAAEVLL-------ALKYFHD--NGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFC--------GTPEFMAPEIL---KEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVF--NAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKR</Hsp_hseq>
      <Hsp_midline>A  R +V+++     +VL +G F  V L K+    R      LK+  +   HD++  + E  +   L   K    +L +   + QT + ++     ME    G ++ +  NQRLS     F   EVL        A+   H     +I+RDLK+ENILL   G+  + D+G   +++                   T  + APE++        T   D WA G LLY++     PF G+ +  +   N  + D   Y  +M   I    + +L  DP+ R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>4.83729e-07</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>900</Hsp_query-to>
      <Hsp_hit-from>200</Hsp_hit-from>
      <Hsp_hit-to>454</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>127</Hsp_positive>
      <Hsp_gaps>57</Hsp_gaps>
      <Hsp_align-len>283</Hsp_align-len>
      <Hsp_qseq>VEEVLAEGGFAIV--FLVKTSG---GVRSALKRMYVNNEHDLKVCQREITIMKELSGHKNIV---GYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYV--LCDFGSATNKILNPQAHGVSAVEDEIKKY-TTLSYRAPEMVNLYNGT----------PITAKSDIWALGCLLYKLCFFTLPF-GESQ----VAICDGNF---TIPDHSRYSHEMHCLIRYMLEPDPDSR</Hsp_qseq>
      <Hsp_hseq>IDEVVGQGAFATVKKAIERTTGKTFAVKIISKRKVIGN---MDGVTRELEVLQKLN-HPRIVRLKGFYEDT---------ESYYMVMEFVSGGDLMDFVAAHGAVG--EDAGREISRQILTAIKYIHSMG--ISHRDLKPDNILIEQDDPVLVKITDFGLA-----KVQGNGSF-----MKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGPLKDF-RISEEARDFIDSLLQVDPNNR</Hsp_hseq>
      <Hsp_midline>++EV+ +G FA V   + +T+G    V+   KR  + N   +    RE+ ++++L+ H  IV   G+ + +             ++ME    G +++ +    + G  E     I      A+  +H     I HRDLK +NIL+  +   +  + DFG A       Q +G       +K +  TL+Y APE++   + +            ++  D+W++GCL+Y +    LPF G +Q      I  G++    + D  R S E    I  +L+ DP++R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>71</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>7.23584e-07</Hsp_evalue>
      <Hsp_query-from>445</Hsp_query-from>
      <Hsp_query-to>903</Hsp_query-to>
      <Hsp_hit-from>811</Hsp_hit-from>
      <Hsp_hit-to>970</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>168</Hsp_align-len>
      <Hsp_qseq>EVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATN-----KILNPQAHGVSAVEDEIKKYT-TLSYRAPEMVNLYNGTP-ITAKSDIWALGCLLYKLCFFTLPF--GESQVAICDGNFTI-----PDHSRYSHEMH-CLIRYMLEPDPDSRP</Hsp_qseq>
      <Hsp_hseq>EYWRLFRQILEALSYIHS--QGIIHRDLKPMNIFIDESRNVKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVL---DGTGHYNEKIDMYSLGIIFFEMIY---PFSTGMERVNILKKLRSVSIEFPPDFDDNKMKVEKKIIRLLIDHDPNKRP</Hsp_hseq>
      <Hsp_midline>E  R+F    EA++ +H     IIHRDLK  NI + ++ N  + DFG A N      IL   +  +    D +     T  Y A E++   +GT     K D+++LG + +++ +   PF  G  +V I     ++     PD      ++   +IR +++ DP+ RP</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>46.9802</Hsp_bit-score>
      <Hsp_score>110</Hsp_score>
      <Hsp_evalue>3.33531e-06</Hsp_evalue>
      <Hsp_query-from>232</Hsp_query-from>
      <Hsp_query-to>900</Hsp_query-to>
      <Hsp_hit-from>298</Hsp_hit-from>
      <Hsp_hit-to>515</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>57</Hsp_gaps>
      <Hsp_align-len>249</Hsp_align-len>
      <Hsp_qseq>NNEHDLKVCQREI-TIMKELSGHKNI---VGYLDSSINAQTSSGVWEVLILMEICR---AGQVVNQMNQRLSTGFTECEVLRIF-CDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILN--------------PQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPFGESQVAICDGNFTIP----DHSRYSHEMHCLIRYMLEPDPDSR</Hsp_qseq>
      <Hsp_hseq>NGKKEIANLEKELETVLK--AKHDNVNRLFGYTVERMGRNNATFVWKIRLLTEYCNYYPLGDLIQ------SVGFVNLATARIWMIRLLEGLEAIH--KLGIVHKCINLETVILVKD-----ADFGSTIPKLVHSTYGYTVLNMLSRYPNKNG-SSVE-----LSPSTWIAPELLKFNNAKP-QRLTDIWQLGVLFIQII------SGSDIVM---NFETPQEFLDSTSMDETLYDLLSKMLNNDPKKR</Hsp_hseq>
      <Hsp_midline>N + ++   ++E+ T++K  + H N+    GY    +    ++ VW++ +L E C     G ++       S GF      RI+     E +  +H  K  I+H+ + +E ++L  +      DFGS   K+++              P  +G S+VE      +  ++ APE++   N  P    +DIW LG L  ++         S + +   NF  P    D +     ++ L+  ML  DP  R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>72</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>1.23611e-06</Hsp_evalue>
      <Hsp_query-from>421</Hsp_query-from>
      <Hsp_query-to>798</Hsp_query-to>
      <Hsp_hit-from>272</Hsp_hit-from>
      <Hsp_hit-to>420</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>155</Hsp_align-len>
      <Hsp_qseq>LSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQ-----------------AHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTP-------ITAKS-----DIWALGCLLYKLCFFTLPFGESQV</Hsp_qseq>
      <Hsp_hseq>LKSGHARFYISEMFC----AVNALHDLG--YTHRDLKPENFLIDAKGHIKLTDFGLAAGTISNERIESMKIRLEKIKDLEFPAFTEKSIEDRRKMYNQLREKEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSST</Hsp_hseq>
      <Hsp_midline>L +G     +  +FC    AV  LH       HRDLK EN L+   G+  L DFG A   I N +                 A    ++ED  K Y  L  +     N   G+P       +  K      D W+LGC+L++      PF  S  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>73</Hit_num>
  <Hit_id>YDL025C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:405344:407206:-1 gene:YDL025C transcript:YDL025C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RTK1 description:Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002183]</Hit_def>
  <Hit_accession>YDL025C</Hit_accession>
  <Hit_len>620</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>1.2413e-06</Hsp_evalue>
      <Hsp_query-from>151</Hsp_query-from>
      <Hsp_query-to>783</Hsp_query-to>
      <Hsp_hit-from>308</Hsp_hit-from>
      <Hsp_hit-to>510</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>228</Hsp_align-len>
      <Hsp_qseq>LAEGGFAIVFLVKTSGGVRSA---LKRMYVNNE----HDLKVCQREITI---MKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSAT-------NKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPF</Hsp_qseq>
      <Hsp_hseq>LGEGASGSVSVVERTDGKLFACKMFRKPHLNNEGTNQSQLANYSKKVTTEFCIGSTLHHENIVETLDMLTEGDT------YLLVMEYA----PYDFFNLVMSNLMTQDEVNCYFKQLCHGVNYLHSMG--LAHRDLKLDNCVVTKDGILKLIDFGSAVVFQYPYEDTIV--KSHGIVGSD---------PYLAPELLKQTSYDPRVA--DVWSIAIIFYCMVLKRFPW</Hsp_hseq>
      <Hsp_midline>L EG    V +V+ + G   A    ++ ++NNE      L    +++T    +     H+NIV  LD      T       L++ME        +  N  +S   T+ EV   F   C  V  LH     + HRDLK++N ++  +G   L DFGSA        + I+  ++HG+   +          Y APE++   +  P  A  D+W++  + Y +     P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>74</Hit_num>
  <Hit_id>YPL026C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:500675:502183:-1 gene:YPL026C transcript:YPL026C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKS1 description:Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway; SKS1 has a paralog, VHS1, that arose from the whole genome duplication [Source:SGD;Acc:S000005947]</Hit_def>
  <Hit_accession>YPL026C</Hit_accession>
  <Hit_len>502</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>1.42971e-06</Hsp_evalue>
      <Hsp_query-from>262</Hsp_query-from>
      <Hsp_query-to>762</Hsp_query-to>
      <Hsp_hit-from>108</Hsp_hit-from>
      <Hsp_hit-to>268</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>185</Hsp_align-len>
      <Hsp_qseq>REITIMKELSGHKNIVG---YLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSAT-NKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLY------NGTPI--------TAKSDIWALGCLLYKL</Hsp_qseq>
      <Hsp_hseq>REIAFQLRVQSHGNIVKIHQVLESSIATFIVMDYYDRDLFTSIVDDKHFVNH-------GIL---IKKVFLQLCSALDHCH--RLGIYHCDIKPENVLLDRNDNAYLCDFGLSTKSKYLAPNVCVGSSY-----------YMAPERI-LYCLNTTTNGIHVDECCSSLPTDTGDIWSLGIILINL</Hsp_hseq>
      <Hsp_midline>REI     +  H NIV     L+SSI        ++  +   I      VN        G     + ++F   C A+   H  +  I H D+K EN+LL  N N  LCDFG +T +K L P     S+            Y APE + LY      NG  +        T   DIW+LG +L  L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>75</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>1.68218e-06</Hsp_evalue>
      <Hsp_query-from>178</Hsp_query-from>
      <Hsp_query-to>771</Hsp_query-to>
      <Hsp_hit-from>86</Hsp_hit-from>
      <Hsp_hit-to>281</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>210</Hsp_align-len>
      <Hsp_qseq>FLVKTSGGVRSALKRMYVNNEHDLK--VCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYV----LCDFGSATNKILNPQAHGVSAVEDEIKKYT----TLSYRAPEMV--NLYNGTPITAKSDIWALGCLLYKLCFF</Hsp_qseq>
      <Hsp_hseq>YITKTQGVV--AIKTM-MTKLHTLQDYTRVREIKFILAIPANDHLIQIFEVFIDSEN----YQLHIVME-CMEQNLYQMMKHRRRRVFSIPSLKSILSQILAGLKHIHEHN--FFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVENKNPYTAYVSTRWYRSPEILLRSGYYSKPL----DIWAFGCVAVEVTVF</Hsp_hseq>
      <Hsp_midline>++ KT G V  A+K M +   H L+     REI  +  +  + +++   +  I+++     +++ I+ME C    +   M  R    F+   +  I       +  +H+      HRDLK ENIL+  +  Y     +   G   N ++     G++   +    YT    T  YR+PE++  + Y   P+    DIWA GC+  ++  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>76</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.3654</Hsp_bit-score>
      <Hsp_score>111</Hsp_score>
      <Hsp_evalue>2.26379e-06</Hsp_evalue>
      <Hsp_query-from>151</Hsp_query-from>
      <Hsp_query-to>765</Hsp_query-to>
      <Hsp_hit-from>450</Hsp_hit-from>
      <Hsp_hit-to>647</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>220</Hsp_align-len>
      <Hsp_qseq>LAEGGFAIVFLVK-TSGGVRSALKRMYVNNEHDLKVCQREITIMKELS--------GHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCE---AVARLHQ-CKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVN--LYNGTPITAKSDIWALGCLLYKLC</Hsp_qseq>
      <Hsp_hseq>IGKGQFSTVYQVTFAQTNKKYAIKAIKPNKYNSLKRILLEIKILNEVTNQITMDQEGKEYIIDYI-SSWKFQNS-----YYIMTELCENGNLDGFLQEQVIAKKKRLEDWRIWKIIVELSLALRFIHDSCH--IVHLDLKPANVMITFEGNLKLGDFGMATHLPLEDK-----SFENEGDR----EYIAPEIISDCTYD-----YKADIFSLGLMIVEIA</Hsp_hseq>
      <Hsp_midline>+ +G F+ V+ V       + A+K +  N  + LK    EI I+ E++        G + I+ Y+ SS   Q S       I+ E+C  G +   + +++       E  RI+    E   A+  +H  C   I+H DLK  N+++   GN  L DFG AT+  L  +     + E+E  +     Y APE+++   Y+      K+DI++LG ++ ++ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>77</Hit_num>
  <Hit_id>YFL029C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:78055:79161:-1 gene:YFL029C transcript:YFL029C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CAK1 description:Cyclin-dependent kinase-activating kinase; required for passage through the cell cycle; phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases [Source:SGD;Acc:S000001865]</Hit_def>
  <Hit_accession>YFL029C</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.2098</Hsp_bit-score>
      <Hsp_score>108</Hsp_score>
      <Hsp_evalue>4.28969e-06</Hsp_evalue>
      <Hsp_query-from>451</Hsp_query-from>
      <Hsp_query-to>741</Hsp_query-to>
      <Hsp_hit-from>134</Hsp_hit-from>
      <Hsp_hit-to>230</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>105</Hsp_align-len>
      <Hsp_qseq>LRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYV-----LCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEM---VNLYNGTPITAKSDIWAL</Hsp_qseq>
      <Hsp_hseq>LSFFRQMVEGIAFLHENK--IIHRDIKPQNIMLTNNTSTVSPKLYIIDFGISYDMANNSQT-SAEPMDSKVTDISTGIYKAPEVLFGVKCYDGG-----VDVWSL</Hsp_hseq>
      <Hsp_midline>L  F    E +A LH+ K  IIHRD+K +NI+L +N + V     + DFG + +   N Q      ++ ++   +T  Y+APE+   V  Y+G       D+W+L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>78</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.2098</Hsp_bit-score>
      <Hsp_score>108</Hsp_score>
      <Hsp_evalue>4.43126e-06</Hsp_evalue>
      <Hsp_query-from>511</Hsp_query-from>
      <Hsp_query-to>783</Hsp_query-to>
      <Hsp_hit-from>273</Hsp_hit-from>
      <Hsp_hit-to>362</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>53</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>99</Hsp_align-len>
      <Hsp_qseq>IIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKK-----YT---TLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPF</Hsp_qseq>
      <Hsp_hseq>VVYRDLKPENCLLNQRGHLVLTDFG------LSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEIL---LGKAYSQNCDWYSLGCLLYDMLVGKPPY</Hsp_hseq>
      <Hsp_midline>+++RDLK EN LL+  G+ VL DFG      L+ ++   SAV++E  +     Y+   T  Y APE++    G   +   D ++LGCLLY +     P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>79</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.2098</Hsp_bit-score>
      <Hsp_score>108</Hsp_score>
      <Hsp_evalue>5.64877e-06</Hsp_evalue>
      <Hsp_query-from>448</Hsp_query-from>
      <Hsp_query-to>828</Hsp_query-to>
      <Hsp_hit-from>263</Hsp_hit-from>
      <Hsp_hit-to>379</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>129</Hsp_align-len>
      <Hsp_qseq>VLRIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSAT--NKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPFGESQVAICDGNFTIP</Hsp_qseq>
      <Hsp_hseq>VRSIMWQLLDGVSYLHQ--NWVLHRDLKPANIMVTIDGCVKIGDLGLARKFHNMLQTLYTGDKVV-------VTIWYRAPEL--LLGARHYTPAVDLWSVGCIFAELIGLQ-PIFKGEEAKLDSKKTVP</Hsp_hseq>
      <Hsp_midline>V  I     + V+ LHQ    ++HRDLK  NI++  +G   + D G A   + +L     G   V        T+ YRAPE+  L      T   D+W++GC+  +L     P  + + A  D   T+P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>80</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.4394</Hsp_bit-score>
      <Hsp_score>106</Hsp_score>
      <Hsp_evalue>7.34543e-06</Hsp_evalue>
      <Hsp_query-from>211</Hsp_query-from>
      <Hsp_query-to>753</Hsp_query-to>
      <Hsp_hit-from>66</Hsp_hit-from>
      <Hsp_hit-to>230</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>185</Hsp_align-len>
      <Hsp_qseq>ALKRMYVNNEHDLKVCQREITIMKELSGHKNIVG--YLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTGFTECEVLRIFCDTCE-AVARLHQCKTPIIHRDLKVENILLH-DNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNGTPITAKSDIWALGCLL</Hsp_qseq>
      <Hsp_hseq>AIKKVPAHTEYK----SRELQILR-IADHPNIVKLQYFFTHLSPQDNK-VYQHLAMECLPETLQI--EIN-RYVTNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSA--KKLEHNQPSISYI-------CSRFYRAPELI--IGCTQYTTQIDIWGLGCVM</Hsp_hseq>
      <Hsp_midline>A+K++  + E+      RE+ I++ ++ H NIV   Y  + ++ Q +  V++ L +  +    Q+  ++N R  T   E  +  I   T + A   L+     + HRD+K  N+L+  + G   +CDFGSA  K L      +S +        +  YRAPE++     T  T + DIW LGC++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>81</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.4394</Hsp_bit-score>
      <Hsp_score>106</Hsp_score>
      <Hsp_evalue>7.74742e-06</Hsp_evalue>
      <Hsp_query-from>478</Hsp_query-from>
      <Hsp_query-to>753</Hsp_query-to>
      <Hsp_hit-from>160</Hsp_hit-from>
      <Hsp_hit-to>239</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>94</Hsp_align-len>
      <Hsp_qseq>AVARLHQCKTPIIHRDLKVENILL-HDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYT-TLSYRAPEMVNLYNGTPITAKSDIWALGCLL</Hsp_qseq>
      <Hsp_hseq>ALLTLHSMS--ICHGDLKPSNILIIPSSGIAKVCDFGSAQRLDDN----------TELKTYFCSRFYRAPEL--LLNSKDYTTQIDIWSLGCII</Hsp_hseq>
      <Hsp_midline>A+  LH     I H DLK  NIL+   +G   +CDFGSA     N           E+K Y  +  YRAPE+  L N    T + DIW+LGC++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>603814887</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056800-RA transcript Note:&quot;Similar to TACR2 Substance-K receptor (Homo sapiens)&quot; offset:0 AED:0.07 eAED:0.07 QI:0|0|0.16|1|1|1|6|2494|372</Iteration_query-def>
  <Iteration_query-len>3613</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2478956101</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056801-RA transcript Note:&quot;Similar to PLA2G12B Group XIIB secretory phospholipase A2-like protein (Homo sapiens)&quot; offset:361 AED:0.08 eAED:0.08 QI:361|0.66|0.75|1|1|1|4|1878|200</Iteration_query-def>
  <Iteration_query-len>2842</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>1917045616</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056802-RA transcript Note:&quot;Similar to micu1 Calcium uptake protein 1, mitochondrial (Xenopus tropicalis)&quot; offset:0 AED:0.36 eAED:0.36 QI:0|0.7|0.81|0.90|0.7|0.81|11|2033|421</Iteration_query-def>
  <Iteration_query-len>3299</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2251812933</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0031265-RA transcript Note:&quot;Protein of unknown function&quot; offset:2 AED:0.29 eAED:0.32 QI:2|0|0|0.5|0|0|2|0|238</Iteration_query-def>
  <Iteration_query-len>716</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>87</Statistics_hsp-len>
      <Statistics_eff-space>353319917</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0027755-RA transcript Note:&quot;Similar to nrg1 Pro-neuregulin-1, membrane-bound isoform (Xenopus laevis)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0|0|5|0|366</Iteration_query-def>
  <Iteration_query-len>1101</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>638516892</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056798-RA transcript Note:&quot;Similar to BMP10 Bone morphogenetic protein 10 (Homo sapiens)&quot; offset:0 AED:0.06 eAED:0.06 QI:0|0|0|1|0|0|2|0|513</Iteration_query-def>
  <Iteration_query-len>1542</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>963340140</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056795-RA transcript Note:&quot;Similar to PF10_0343 S-antigen protein (Plasmodium falciparum (isolate 3D7))&quot; offset:0 AED:0.31 eAED:0.58 QI:0|0|0|1|0|0|2|0|420</Iteration_query-def>
  <Iteration_query-len>1263</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>92</Statistics_hsp-len>
      <Statistics_eff-space>758959243</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056824-RA transcript Note:&quot;Similar to znf503 Zinc finger protein 503 (Danio rerio)&quot; offset:31 AED:0.05 eAED:0.05 QI:31|1|1|1|1|1|2|759|618</Iteration_query-def>
  <Iteration_query-len>2647</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1777537328</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056825-RA transcript Note:&quot;Similar to NTSR1 Neurotensin receptor type 1 (Homo sapiens)&quot; offset:0 AED:0.16 eAED:0.16 QI:0|0|0|1|0|0.5|2|0|432</Iteration_query-def>
  <Iteration_query-len>1299</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>92</Statistics_hsp-len>
      <Statistics_eff-space>786641647</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056828-RA transcript Note:&quot;Similar to eif4e Eukaryotic translation initiation factor 4E (Xenopus laevis)&quot; offset:527 AED:0.10 eAED:0.10 QI:527|0.8|1|1|0.6|0.83|6|0|211</Iteration_query-def>
  <Iteration_query-len>1163</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YOL139C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:60383:61024:-1 gene:YOL139C transcript:YOL139C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC33 description:mRNA cap binding protein and translation initiation factor eIF4E; the eIF4E-cap complex is responsible for mediating cap-dependent mRNA translation via interactions with translation initiation factor eIF4G (Tif4631p or Tif4632p); protein abundance increases in response to DNA replication stress; mutants are defective for adhesion and pseudohyphal growth; human homolog EIF4E can complement yeast cdc33 null mutant [Source:SGD;Acc:S000005499]</Hit_def>
  <Hit_accession>YOL139C</Hit_accession>
  <Hit_len>213</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.8113</Hsp_bit-score>
      <Hsp_score>216</Hsp_score>
      <Hsp_evalue>1.0012e-20</Hsp_evalue>
      <Hsp_query-from>723</Hsp_query-from>
      <Hsp_query-to>1112</Hsp_query-to>
      <Hsp_hit-from>34</Hsp_hit-from>
      <Hsp_hit-to>200</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>168</Hsp_align-len>
      <Hsp_qseq>EMKHPLENRWALWFFKN--DKTKSWQANLRLISKVDTVEDFWALYNHIQVASHLMSGCDYSLFK------------------------------------LLCLIGEAFDDHSDNICGAVVNIRGKGDKVAVWTRDCENREGIMTIGKVYKERLGLSGKMHLGYESHS</Hsp_qseq>
      <Hsp_hseq>DVKHPLNTKWTLWYTKPAVDKSESWSDLLRPVTSFQTVEEFWAIIQNIPEPHELPLKSDYHVFRNDVRPEWEDEANAKGGKWSFQLRGKGADIDELWLRTLLAVIGETIDEDDSQINGVVLSIRKGGNKFALWTK-SEDKEPLLRIGGKFKQVLKLTDDGHLEFFPHS</Hsp_hseq>
      <Hsp_midline>++KHPL  +W LW+ K   DK++SW   LR ++   TVE+FWA+  +I     L    DY +F+                                    LL +IGE  D+    I G V++IR  G+K A+WT+  E++E ++ IG  +K+ L L+   HL +  HS</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>684786232</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056829-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.17 eAED:0.17 QI:0|0.8|1|1|0.4|0.66|6|425|147</Iteration_query-def>
  <Iteration_query-len>869</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>89</Statistics_hsp-len>
      <Statistics_eff-space>465333400</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056830-RA transcript Note:&quot;Similar to PRSS12 Neurotrypsin (Saguinus labiatus)&quot; offset:0 AED:0.27 eAED:0.27 QI:0|0.1|0.18|0.72|1|1|11|663|427</Iteration_query-def>
  <Iteration_query-len>1947</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1261098251</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056831-RA transcript Note:&quot;Similar to Dapp1 Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (Mus musculus)&quot; offset:342 AED:0.42 eAED:0.42 QI:342|0.6|0.66|1|1|1|6|0|166</Iteration_query-def>
  <Iteration_query-len>843</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>89</Statistics_hsp-len>
      <Statistics_eff-space>446720064</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056832-RA transcript Note:&quot;Similar to Cxxc5 CXXC-type zinc finger protein 5 (Rattus norvegicus)&quot; offset:127 AED:0.00 eAED:0.00 QI:127|1|1|1|1|1|2|281|395</Iteration_query-def>
  <Iteration_query-len>1596</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>1004626146</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

