<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0042762-RA transcript Note:&quot;Similar to HSD3B7 3 beta-hydroxysteroid dehydrogenase type 7 (Homo sapiens)&quot; offset:47 AED:0.27 eAED:0.27 QI:47|0|0|0.71|0.83|0.85|7|318|343</BlastOutput_query-def>
  <BlastOutput_query-len>1397</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0042762-RA transcript Note:&quot;Similar to HSD3B7 3 beta-hydroxysteroid dehydrogenase type 7 (Homo sapiens)&quot; offset:47 AED:0.27 eAED:0.27 QI:47|0|0|0.71|0.83|0.85|7|318|343</Iteration_query-def>
  <Iteration_query-len>1397</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YGL001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:495453:496502:-1 gene:YGL001C transcript:YGL001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ERG26 description:C-3 sterol dehydrogenase; catalyzes the second of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; human homolog NSDHL implicated in CK syndrome, and can complement yeast null mutant; molecular target of natural product and antifungal compound FR171456 [Source:SGD;Acc:S000002969]</Hit_def>
  <Hit_accession>YGL001C</Hit_accession>
  <Hit_len>349</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.9442</Hsp_bit-score>
      <Hsp_score>180</Hsp_score>
      <Hsp_evalue>6.68829e-15</Hsp_evalue>
      <Hsp_query-from>285</Hsp_query-from>
      <Hsp_query-to>1037</Hsp_query-to>
      <Hsp_hit-from>106</Hsp_hit-from>
      <Hsp_hit-to>345</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>256</Hsp_align-len>
      <Hsp_qseq>NVVRACVEASVPILVYTSSTEVVGPNKQFDPFFRGNEDTPYKVSHNNFYSSTKCEAEKIVLSANGTKLITGGKLSTCVIRPSGIYGEKHDSLEQAYRRAQKKGGVVIRVSPTNSEHGRVYVGNVAWMHVMAAQAL--EKKPQVVGGQVYYACDESPFMNYTDFNMEFFSELGFRISGERMILPYYVLYL---FAILQEVLHVVLGPLMGFKPILNRYMLNSLISTFSVSSDKARRHFNYEPLYSWAECREHTVAWL</Hsp_qseq>
      <Hsp_hseq>NVIDMCKKCGVNILVYTSSAGVIFNGQDV---HNADETWPIPEVPMDAYNETKAIAEDMVLKANDPS----SDFYTVALRPAGIFGPGDRQLVPGLRQVAKLGQSKFQIGDNNNLFDWTYAGNVADAHVLAAQKLLDPKTRTAVSGETFFITNDTP---------TYFWALARTVWKADGHIDKHVIVLKRPVAICAGYLSEWVSKMLGKEPGLTPFRVKIVCAYRYHNIAKAKKLLGYTPRVGIEEGINKTLAWM</Hsp_hseq>
      <Hsp_midline>NV+  C +  V ILVYTSS  V+   +        +E  P      + Y+ TK  AE +VL AN           T  +RP+GI+G     L    R+  K G    ++   N+     Y GNVA  HV+AAQ L   K    V G+ ++  +++P          +F  L   +      +  +V+ L    AI    L   +  ++G +P L  + +  + +    +  KA++   Y P     E    T+AW+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>93</Statistics_hsp-len>
      <Statistics_eff-space>855699324</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0033245-RA transcript Note:&quot;Similar to SETD1B Histone-lysine N-methyltransferase SETD1B (Gallus gallus)&quot; offset:3325 AED:1.00 eAED:1.00 QI:3325|0|0|0|0.5|0.57|19|973|1218</Iteration_query-def>
  <Iteration_query-len>7955</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YHR119W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:346043:349285:1 gene:YHR119W transcript:YHR119W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SET1 description:Histone methyltransferase, subunit of the COMPASS (Set1C) complex; COMPASS methylates histone H3K4; Set1p-dependent H3K4 trimethylation recruits Nrd1p, allowing efficient termination of snoRNAs and cryptic unstable transcripts (CUTs) by Nrd1p-Nab3p-Sen1p pathway; modulates histone acetylation levels in promoter proximal regions to ensure efficient Nrd1p-dependent termination; required in transcriptional silencing near telomeres and at silent mating type loci; has a SET domain [Source:SGD;Acc:S000001161]</Hit_def>
  <Hit_accession>YHR119W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>186.422</Hsp_bit-score>
      <Hsp_score>472</Hsp_score>
      <Hsp_evalue>1.03569e-47</Hsp_evalue>
      <Hsp_query-from>6587</Hsp_query-from>
      <Hsp_query-to>6979</Hsp_query-to>
      <Hsp_hit-from>947</Hsp_hit-from>
      <Hsp_hit-to>1080</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>85</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>134</Hsp_align-len>
      <Hsp_qseq>IHDWGLFALEPIAADEMVIEYVGEGIRQVIADMRERHYEKEGIGSSYMFRVDHDHIIDATKCGNLARFINHSCNPNCYAKIITVDSHKKIVIYSKQAIAVNEEITYDYKFPIE---DEKIPCLCGAENCRGTLN</Hsp_qseq>
      <Hsp_hseq>IHNWGLYALDSIAAKEMIIEYVGERIRQPVAEMREKRYLKNGIGSSYLFRVDENTVIDATKKGGIARFINHCCDPNCTAKIIKVGGRRRIVIYALRDIAASEELTYDYKFEREKDDEERLPCLCGAPNCKGFLN</Hsp_hseq>
      <Hsp_midline>IH+WGL+AL+ IAA EM+IEYVGE IRQ +A+MRE+ Y K GIGSSY+FRVD + +IDATK G +ARFINH C+PNC AKII V   ++IVIY+ + IA +EE+TYDYKF  E   +E++PCLCGA NC+G LN</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YJL168C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:102227:104428:-1 gene:YJL168C transcript:YJL168C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SET2 description:Histone methyltransferase with a role in transcriptional elongation; methylates H3 lysine 36 (H3K36), which suppresses incorporation of acetylated histones and signals for the deacetylation of these histones within transcribed genes; associates with the C-terminal domain(CTD) of Rpo21p; H3K36me3 (trimethylation) requires Spt6p, proline 38 on H3, CTD of Rpo21p, Ctk1p, and C-terminal SRI domain of Ste2p; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000003704]</Hit_def>
  <Hit_accession>YJL168C</Hit_accession>
  <Hit_len>733</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>4.15103e-13</Hsp_evalue>
      <Hsp_query-from>6596</Hsp_query-from>
      <Hsp_query-to>6976</Hsp_query-to>
      <Hsp_hit-from>132</Hsp_hit-from>
      <Hsp_hit-to>259</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>130</Hsp_align-len>
      <Hsp_qseq>WGLFALEPIAADEMVIEYVGEGIRQVIADMRERHYEKEGIGSSYMFRVDHDHIIDATKCGNLARFINHSCNPNCYAKIITVDSHKKIVIYSKQAIAVNEEITYDY---KFPIEDEKIPCLCGAENCRGTL</Hsp_qseq>
      <Hsp_hseq>YGVRAEQDIEANQFIYEYKGEVIEEMEFRDRLIDYDQRHFKHFYFMMLQNGEFIDATIKGSLARFCNHSCSPNAYVNKWVVKDKLRMGIFAQRKILKGEEITFDYNVDRYGAQAQK--CYCEEPNCIGFL</Hsp_hseq>
      <Hsp_midline>+G+ A + I A++ + EY GE I ++    R   Y++      Y   + +   IDAT  G+LARF NHSC+PN Y     V    ++ I++++ I   EEIT+DY   ++  + +K  C C   NC G L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>107</Statistics_hsp-len>
      <Statistics_eff-space>5616813648</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053875-RA transcript Note:&quot;Similar to TMEM120B Transmembrane protein 120B (Homo sapiens)&quot; offset:219 AED:0.26 eAED:0.26 QI:219|0.8|0.90|0.90|1|1|11|0|290</Iteration_query-def>
  <Iteration_query-len>1092</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>631576491</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053877-RA transcript Note:&quot;Similar to hpd 4-hydroxyphenylpyruvate dioxygenase (Danio rerio)&quot; offset:0 AED:0.41 eAED:0.41 QI:0|0.16|0.25|0.31|0.90|0.96|32|863|1006</Iteration_query-def>
  <Iteration_query-len>3884</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YNL243W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:188051:190957:1 gene:YNL243W transcript:YNL243W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLA2 description:Adaptor protein that links actin to clathrin and endocytosis; involved in membrane cytoskeleton assembly and cell polarization; present in the actin cortical patch of the emerging bud tip; dimer in vivo [Source:SGD;Acc:S000005187]</Hit_def>
  <Hit_accession>YNL243W</Hit_accession>
  <Hit_len>968</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.6481</Hsp_bit-score>
      <Hsp_score>200</Hsp_score>
      <Hsp_evalue>5.72733e-16</Hsp_evalue>
      <Hsp_query-from>1717</Hsp_query-from>
      <Hsp_query-to>1974</Hsp_query-to>
      <Hsp_hit-from>807</Hsp_hit-from>
      <Hsp_hit-to>896</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>90</Hsp_align-len>
      <Hsp_qseq>EFYAKNSRWTEGLISASKAVGWGATMLVEAADKVVQG----DGKFEELVVCSHEIAASTAQLVAASKVKAERNSGKLARLQHASRGVNEA</Hsp_qseq>
      <Hsp_hseq>QFYLKNSRWTEGLISAAKAVAGATNVLITTASKLITSEDNENTSPEQFIVASKEVAASTIQLVAASRVKTSIHSKAQDKLEHCSKDVTDA</Hsp_hseq>
      <Hsp_midline>+FY KNSRWTEGLISA+KAV     +L+  A K++      +   E+ +V S E+AAST QLVAAS+VK   +S    +L+H S+ V +A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2681228131</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0042768-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:1.00 eAED:1.00 QI:0|-1|0|0|-1|1|1|0|178</Iteration_query-def>
  <Iteration_query-len>537</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>84</Statistics_hsp-len>
      <Statistics_eff-space>224168365</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053880-RA transcript Note:&quot;Similar to hvcn1 Voltage-gated hydrogen channel 1 (Danio rerio)&quot; offset:0 AED:0.15 eAED:0.15 QI:0|0.5|0.6|0.6|1|1|5|1252|272</Iteration_query-def>
  <Iteration_query-len>2071</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1354597398</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053881-RA transcript Note:&quot;Similar to SPNS1 Protein spinster homolog 1 (Bos taurus)&quot; offset:0 AED:0.30 eAED:0.35 QI:0|0.5|0.85|1|1|1|7|0|578</Iteration_query-def>
  <Iteration_query-len>1737</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1106940428</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053882-RA transcript Note:&quot;Similar to CUX1 Protein CASP (Homo sapiens)&quot; offset:0 AED:0.09 eAED:0.09 QI:0|0.73|0.7|1|0.84|0.9|20|1787|581</Iteration_query-def>
  <Iteration_query-len>3533</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YKL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:110464:112503:-1 gene:YKL179C transcript:YKL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:COY1 description:Golgi membrane protein with similarity to mammalian CASP; genetic interactions with GOS1 (encoding a Golgi snare protein) suggest a role in Golgi function [Source:SGD;Acc:S000001662]</Hit_def>
  <Hit_accession>YKL179C</Hit_accession>
  <Hit_len>679</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>144.821</Hsp_bit-score>
      <Hsp_score>364</Hsp_score>
      <Hsp_evalue>4.39122e-36</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>1776</Hsp_query-to>
      <Hsp_hit-from>21</Hsp_hit-from>
      <Hsp_hit-to>645</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>162</Hsp_identity>
      <Hsp_positive>289</Hsp_positive>
      <Hsp_gaps>79</Hsp_gaps>
      <Hsp_align-len>648</Hsp_align-len>
      <Hsp_qseq>MQRELDQTAAELAIRQDDSEQSRRRLIDQSRDFKKNTPEELRKQVAPLLKSFQGEIDALSKRSKEAETAFLNVYKRFIDVPDPVGVLEVAMQLQQKVQRLNDVEMENQKLRETLEEYNKEFAHVKNQEVTIKALKDRIREYEQTAGARVETLALEREQKIRGEYDERERLLQEDQQTLRKKLGEAEVRVSILQSDIIM-MDLXXXXXXXXXXXXXXXSLKEQLSAGGGVRPQADVGGSTV------------PLGDSQARLAFDHELAAKEREVAQLVDDVQRLQAALGQQRESG--ASHKLEEQLKA---------------------QADYSVIKSELNILKSMEFSSSLD------KSEAQESKPLEVLLLEKNRALQWXXXXXXXXXXXXELQEEHSEVVKVGAEQKQLIIQLEHDLSTLHSMGSITRPDAEGTEYTSTPMENVPDPVREASSRFFAPATRGEAPSSPSVELP-----PGQVDSLLSIISSQRERFRLRNQELESEARMHQQTVQALHAELDNLRADNVKLYEKIKFLQSYPGRGARED------DTEQRYSTQYEERLDPFASFGHRE-RQRKYMSLSPWDK--ATLSMVLYKTAWSESVGRDCAAYSDHLHKFHENDAAGI*CVPGSWSPEV</Hsp_qseq>
      <Hsp_hseq>LQRELDADVIEIKDKETLSLNSRKSLATETKKFKKLEPEEKLNNVNKIIKQYQREIDNLTQRSKFSEKVLFDVYEKLSEAPDPQPLLQSSLE---KLGKIDD----SKELKEKISYLEDKLAKYADYET----LKSRLLDLEQSSAKTLAKRLTAKTQEINSTWEEKGRNWKEREADLLKQLTNVQEQNKALEAKISKNIDIEGNGNEDGDQENNQKEVSTRIAEYNLVTQELETTQARIYQLEKRNEELSGALAKATSEAEKETELHAKELKLNQLESENALLSASYEQERKSTSHAINELKEQLNSVVAESESYKSELETVRRKLNNYSDYNKIKEELSALKKIEFGVNEDDSDNDIRSEDKNDNTFESSLLSANKKLQATLAEYRSKSTAQE--EERNEL-------KKSVDQLKQQIATLKEANEKLETDLEKVENVSPHFNETASMMSGVTRQMNNRTSHKMSPTSSIIGIPEDGELSGNQSTILPIVTKQRDRFRSRNMDLEKQLRQGNSEKGKLKLEISKLKGDNTKLYERIRYLQSYNNNNAPVNQSTERIDVESQYSRVYDESLHPMANFRQNELNHYKNKKLSALEKLFSSFAKVILQNKMTRMV---FLFYCIGLHGLVFMMSMYVINISGYMTPEV</Hsp_hseq>
      <Hsp_midline>+QRELD    E+  ++  S  SR+ L  +++ FKK  PEE    V  ++K +Q EID L++RSK +E    +VY++  + PDP  +L+ +++   K+ +++D    +++L+E +     + A   + E     LK R+ + EQ++   +      + Q+I   ++E+ R  +E +  L K+L   + +   L++ I   +D+E         +   + +  +++    V  + +   + +             L  + +    + EL AKE ++ QL  +   L A+  Q+R+S   A ++L+EQL +                      +DY+ IK EL+ LK +EF  + D      +SE +     E  LL  N+ LQ +           E  EE +E+       K+ + QL+  ++TL         D E  E  S         +   + +     +   +P+S  + +P      G   ++L I++ QR+RFR RN +LE + R        L  E+  L+ DN KLYE+I++LQSY    A  +      D E +YS  Y+E L P A+F   E    K   LS  +K  ++ + V+ +   +  V      Y   LH      +  +  + G  +PEV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2418274492</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053883-RA transcript Note:&quot;Similar to ATP2A1 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (Oryctolagus cuniculus)&quot; offset:100 AED:0.23 eAED:0.27 QI:100|0|0|0.88|0.81|0.82|17|0|714</Iteration_query-def>
  <Iteration_query-len>2245</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YGL167C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:187616:190468:-1 gene:YGL167C transcript:YGL167C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PMR1 description:High affinity Ca2+/Mn2+ P-type ATPase; required for Ca2+ and Mn2+ transport into Golgi; involved in Ca2+ dependent protein sorting, processing; D53A mutant (Mn2+ transporting) is rapamycin sensitive, Q783A mutant (Ca2+ transporting) is rapamycin resistant; Mn2+ transport into Golgi lumen required for rapamycin sensitivity; mutations in human homolog ATP2C1 cause acantholytic skin condition Hailey-Hailey disease; human ATP2C1 can complement yeast null mutant [Source:SGD;Acc:S000003135]</Hit_def>
  <Hit_accession>YGL167C</Hit_accession>
  <Hit_len>950</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>332.413</Hsp_bit-score>
      <Hsp_score>851</Hsp_score>
      <Hsp_evalue>1.41708e-101</Hsp_evalue>
      <Hsp_query-from>50</Hsp_query-from>
      <Hsp_query-to>1972</Hsp_query-to>
      <Hsp_hit-from>135</Hsp_hit-from>
      <Hsp_hit-to>816</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>237</Hsp_identity>
      <Hsp_positive>377</Hsp_positive>
      <Hsp_gaps>113</Hsp_gaps>
      <Hsp_align-len>718</Hsp_align-len>
      <Hsp_qseq>ERNAEGAIEALKEYEPEMGKVYR--QDRRILQLVKARDLVPGDIVEIAVGDKVPADVRLTSIKSTTLRVDQSILTGESISVIKHTDAI--------PDPRAVNQDKKNMLFSGTNIXXXXXXXXXXXXXXHTEIGKIRDAMVSTQQDKTPLQQKLDEFGKQLSKVISFVCVA-VWLINIGHFSDPVHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDSVEGDSCSLHEFNISGSTYTPDGEVLKDNNRVQTGKYDGLVELATICTLCNDSSLDYNEMNVFGTELNGLSKVERANTCNNVIKQLMKKEFTLEFSRDRKSMSVYCVPSGSTGKFQGP-----RMFVKGAPEGVVE-------------------------RCSH------VRV-GSTKV---------------DLTFVGVVAMLDPPRREVSHSIALCREAGIRVMMITGDNKGTAVAICRRIGIFGEEENVEGRAYTGREFDDLPVEQQRQAVQRACCFARVEPAHKSKIVQYLQSFNEITAM-------------AEIGIAMGS-GTAVAKSASEMVLADDNFASIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNRPPRSPKEGLISGWLFFRYM</Hsp_qseq>
      <Hsp_hseq>EYRSEKSLEALNKLVPAECHLMRCGQESHVL----ASTLVPGDLVHFRIGDRIPADIRI--IEAIDLSIDESNLTGENEPVHKTSQTIEKSSFNDQPNSIVPISERSCIAYMGTLVKEGHGKGIVVGTGTNTSFGAVFEMMNNIEKPKTPLQLTMDKLGKDLS-LVSFIVIGMICLVGI------IQGRSWLE----MFQISVSLAVAAIPEGLPIIVTVTLALGVLRMAKRKAIVRRLPSVETLGSVNVICSDKTGTLTSNHMTVSKLWCLDSM---SNKLNVLSLDKNKKTKNS-----NGNLKNYLTEDVRETLTIGNLCNNASFSQEHAIFLGNPTDVALLEQLANFEMPDIRNTVQKVQELPFNSKRKLMAT---------KILNPVDNKCTVYVKGAFERILEYSTSYLKSKGKKTEKLTEAQKATINECANSMASEGLRVFGFAKLTLSDSSTPLTEDLIKDLTFTGLIGMNDPPRPNVKFAIEQLLQGGVHIIMITGDSENTAVNIAKQIGIPVIDPKLS--VLSGDKLDEMSDDQLANVIDHVNIFARATPEHKLNIVRALRKRGDVVAMTGDGVNDAPALKLSDIGVSMGRIGTDVAKEASDMVLTDDDFSTILTAIEEGKGIFNNIQNFLTFQLSTSVAALSLVALSTAFKLPNPLNAMQILWINILMDGPPAQSLGVEPVDHEVMKKPPRKRTDKILTHDVMKRLL</Hsp_hseq>
      <Hsp_midline>E  +E ++EAL +  P    + R  Q+  +L    A  LVPGD+V   +GD++PAD+R+  I++  L +D+S LTGE+  V K +  I        P+      ++  + + GT +  G   G+VV TG +T  G + + M + ++ KTPLQ  +D+ GK LS ++SF+ +  + L+ I      + G SWL      F+I+V+LAVAAIPEGLP ++T  LALG  RMAK+ AIVR LPSVETLG  +VICSDKTGTLT+N M+V +++ LDS+   S  L+  ++  +  T +      N  ++    + + E  TI  LCN++S         G   +     + AN     I+  ++K   L F+  RK M+          K   P      ++VKGA E ++E                          C++      +RV G  K+               DLTF G++ M DPPR  V  +I    + G+ ++MITGD++ TAV I ++IGI   +  +     +G + D++  +Q    +     FAR  P HK  IV+ L+   ++ AM             ++IG++MG  GT VAK AS+MVL DD+F++I+ A+EEG+ I+NN++ F+ + +S++V  +  + L+ A   P  L  +Q+LW+N++ DG PA +LG  P D ++M +PPR   + +++  +  R +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YDR039C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:531307:534582:-1 gene:YDR039C transcript:YDR039C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ENA2 description:P-type ATPase sodium pump; involved in Na+ efflux to allow salt tolerance; likely not involved in Li+ efflux [Source:SGD;Acc:S000002446]</Hit_def>
  <Hit_accession>YDR039C</Hit_accession>
  <Hit_len>1091</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>151.369</Hsp_bit-score>
      <Hsp_score>381</Hsp_score>
      <Hsp_evalue>3.45015e-38</Hsp_evalue>
      <Hsp_query-from>1265</Hsp_query-from>
      <Hsp_query-to>1981</Hsp_query-to>
      <Hsp_hit-from>638</Hsp_hit-from>
      <Hsp_hit-to>901</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>92</Hsp_identity>
      <Hsp_positive>142</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>266</Hsp_align-len>
      <Hsp_qseq>DLTFVGVVAMLDPPRREVSHSIALCREAGIRVMMITGDNKGTAVAICRRIGIFG------EEENVEGRAYTGREFDDLPVEQQRQAVQRACCFARVEPAHKSKIVQYLQSFNEITAM-------------AEIGIAMG-SGTAVAKSASEMVLADDNFASIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEA-------LIPVQLLWVNLVTDGLPATALGFNPPDLDIMNRPPRSPKEGLISGWLFFRYMAIG</Hsp_qseq>
      <Hsp_hseq>DLVFLGLIGIYDPPRNETAGAVKKFHQAGINVHMLTGDFVGTAKAIAQEVGILPTNLYHYSQEIVDSMVMTGSQFDGLSEEEVDDLPVLPLVIARCSPQTKVRMIEALHRRKKFCAMTGDGVNDSPSLKMANVGIAMGINGSDVSKEASDIVLSDDNFASILNAVEEGRRMTDNIQKFVLQLLAENVAQ--ALYLIIGLVFRDENGKSVFPLSPVEVLWIIVVTSCFPAMGLGLEKAAPDLMDRPPHDSEVGIFTWEVIIDTFAYG</Hsp_hseq>
      <Hsp_midline>DL F+G++ + DPPR E + ++    +AGI V M+TGD  GTA AI + +GI         +E V+    TG +FD L  E+           AR  P  K ++++ L    +  AM             A +GIAMG +G+ V+K AS++VL+DDNFASI+ AVEEGR + +N+++F+  L++ NV +   ++L   L F +        L PV++LW+ +VT   PA  LG      D+M+RPP   + G+ +  +     A G</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>104.375</Hsp_bit-score>
      <Hsp_score>259</Hsp_score>
      <Hsp_evalue>2.32125e-23</Hsp_evalue>
      <Hsp_query-from>50</Hsp_query-from>
      <Hsp_query-to>829</Hsp_query-to>
      <Hsp_hit-from>112</Hsp_hit-from>
      <Hsp_hit-to>386</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>91</Hsp_identity>
      <Hsp_positive>145</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>291</Hsp_align-len>
      <Hsp_qseq>ERNAEGAIEALKEYEPEMGKVYRQDRRILQLVKARDLVPGDIVEIAVGDKVPADVRLTSIKSTTLRVDQSILTGESISVIKHTDAI--PDPRAVNQDKKNMLFSGTNIXXXXXXXXXXXXXXHTEIGKI------------RDAMVSTQQDK-----------------TPLQQKLDEFGKQLSKVISFVCVAVWLINIGHFSDPVHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFI</Hsp_qseq>
      <Hsp_hseq>EYKATKTMNSLKNLSSPNAHVIRNGKS--ETINSKDVVPGDICLVKVGDTIPADLRL--IETKNFDTDESLLTGESLPVSKDANLVFGKEEETSVGDRLNLAFSSSAVVKGRAKGIVIKTALNSEIGKIAKSLQGDSGLISRDPSKSWLQNTWISTKKVTGAFLGTNVGTPLHRKL----SKLAVLLFWIAVLFAIIVMASQKFDVDK----RVAIY----AICVALSMIPSSLVVVLTITMSVGAAVMVSRNVIVRKLDSLEALGAVNDICSDKTGTLTQGKMLARQIWI</Hsp_hseq>
      <Hsp_midline>E  A   + +LK        V R  +   + + ++D+VPGDI  + VGD +PAD+RL  I++     D+S+LTGES+ V K  + +   +      D+ N+ FS + +  GRA G+V+ T +++EIGKI            RD   S  Q+                  TPL +KL     +L+ ++ ++ V   +I +      V      R A+Y    A+ +A++ IP  L  V+T  +++G   M  +N IVR L S+E LG  + ICSDKTGTLT  +M   +++I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YDR038C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:527422:530697:-1 gene:YDR038C transcript:YDR038C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ENA5 description:Protein with similarity to P-type ATPase sodium pumps; member of the Na+ efflux ATPase family [Source:SGD;Acc:S000002445]</Hit_def>
  <Hit_accession>YDR038C</Hit_accession>
  <Hit_len>1091</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>150.984</Hsp_bit-score>
      <Hsp_score>380</Hsp_score>
      <Hsp_evalue>4.08248e-38</Hsp_evalue>
      <Hsp_query-from>1265</Hsp_query-from>
      <Hsp_query-to>1981</Hsp_query-to>
      <Hsp_hit-from>638</Hsp_hit-from>
      <Hsp_hit-to>901</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>92</Hsp_identity>
      <Hsp_positive>142</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>266</Hsp_align-len>
      <Hsp_qseq>DLTFVGVVAMLDPPRREVSHSIALCREAGIRVMMITGDNKGTAVAICRRIGIFG------EEENVEGRAYTGREFDDLPVEQQRQAVQRACCFARVEPAHKSKIVQYLQSFNEITAM-------------AEIGIAMG-SGTAVAKSASEMVLADDNFASIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEA-------LIPVQLLWVNLVTDGLPATALGFNPPDLDIMNRPPRSPKEGLISGWLFFRYMAIG</Hsp_qseq>
      <Hsp_hseq>DLVFLGLIGIYDPPRNETAGAVKKFHQAGINVHMLTGDFVGTAKAIAQEVGILPTNLYHYSQEIVDSMVMTGSQFDGLSEEEVDDLPVLPLVIARCSPQTKVRMIEALHRRKKFCAMTGDGVNDSPSLKMANVGIAMGINGSDVSKEASDIVLSDDNFASILNAVEEGRRMTDNIQKFVLQLLAENVAQ--ALYLIIGLVFRDENGKSVFPLSPVEVLWIIVVTSCFPAMGLGLEKAAPDLMDRPPNDSEVGIFTWEVIIDTFAYG</Hsp_hseq>
      <Hsp_midline>DL F+G++ + DPPR E + ++    +AGI V M+TGD  GTA AI + +GI         +E V+    TG +FD L  E+           AR  P  K ++++ L    +  AM             A +GIAMG +G+ V+K AS++VL+DDNFASI+ AVEEGR + +N+++F+  L++ NV +   ++L   L F +        L PV++LW+ +VT   PA  LG      D+M+RPP   + G+ +  +     A G</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>104.375</Hsp_bit-score>
      <Hsp_score>259</Hsp_score>
      <Hsp_evalue>2.26197e-23</Hsp_evalue>
      <Hsp_query-from>50</Hsp_query-from>
      <Hsp_query-to>829</Hsp_query-to>
      <Hsp_hit-from>112</Hsp_hit-from>
      <Hsp_hit-to>386</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>91</Hsp_identity>
      <Hsp_positive>145</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>291</Hsp_align-len>
      <Hsp_qseq>ERNAEGAIEALKEYEPEMGKVYRQDRRILQLVKARDLVPGDIVEIAVGDKVPADVRLTSIKSTTLRVDQSILTGESISVIKHTDAI--PDPRAVNQDKKNMLFSGTNIXXXXXXXXXXXXXXHTEIGKI------------RDAMVSTQQDK-----------------TPLQQKLDEFGKQLSKVISFVCVAVWLINIGHFSDPVHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFI</Hsp_qseq>
      <Hsp_hseq>EYKATKTMNSLKNLSSPNAHVIRNGKS--ETINSKDVVPGDICLVKVGDTIPADLRL--IETKNFDTDESLLTGESLPVSKDANLVFGKEEETSVGDRLNLAFSSSAVVKGRAKGIVIKTALNSEIGKIAKSLQGDSGLISRDPSKSWLQNTWISTKKVTGAFLGTNVGTPLHRKL----SKLAVLLFWIAVLFAIIVMASQKFDVDK----RVAIY----AICVALSMIPSSLVVVLTITMSVGAAVMVSRNVIVRKLDSLEALGAVNDICSDKTGTLTQGKMLARQIWI</Hsp_hseq>
      <Hsp_midline>E  A   + +LK        V R  +   + + ++D+VPGDI  + VGD +PAD+RL  I++     D+S+LTGES+ V K  + +   +      D+ N+ FS + +  GRA G+V+ T +++EIGKI            RD   S  Q+                  TPL +KL     +L+ ++ ++ V   +I +      V      R A+Y    A+ +A++ IP  L  V+T  +++G   M  +N IVR L S+E LG  + ICSDKTGTLT  +M   +++I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YDR040C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:535192:538467:-1 gene:YDR040C transcript:YDR040C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ENA1 description:P-type ATPase sodium pump; involved in Na+ and Li+ efflux to allow salt tolerance [Source:SGD;Acc:S000002447]</Hit_def>
  <Hit_accession>YDR040C</Hit_accession>
  <Hit_len>1091</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>150.984</Hsp_bit-score>
      <Hsp_score>380</Hsp_score>
      <Hsp_evalue>4.66246e-38</Hsp_evalue>
      <Hsp_query-from>1265</Hsp_query-from>
      <Hsp_query-to>1981</Hsp_query-to>
      <Hsp_hit-from>638</Hsp_hit-from>
      <Hsp_hit-to>901</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>93</Hsp_identity>
      <Hsp_positive>144</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>266</Hsp_align-len>
      <Hsp_qseq>DLTFVGVVAMLDPPRREVSHSIALCREAGIRVMMITGDNKGTAVAICRRIGIFG------EEENVEGRAYTGREFDDLPVEQQRQAVQRACCFARVEPAHKSKIVQYL---QSFNEITA----------MAEIGIAMG-SGTAVAKSASEMVLADDNFASIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEA-------LIPVQLLWVNLVTDGLPATALGFNPPDLDIMNRPPRSPKEGLISGWLFFRYMAIG</Hsp_qseq>
      <Hsp_hseq>DLVFLGLIGIYDPPRNETAGAVKKFHQAGINVHMLTGDFVGTAKAIAQEVGILPTNLYHYSQEIVDSMVMTGSQFDGLSEEEVDDLPVLPLVIARCSPQTKVRMIEALHRRKKFCTMTGDGVNDSPSLKMANVGIAMGINGSDVSKEASDIVLSDDNFASILNAVEEGRRMTDNIQKFVLQLLAENVAQ--ALYLIIGLVFRDENGKSVFPLSPVEVLWIIVVTSCFPAMGLGLEKAAPDLMDRPPHDSEVGIFTWEVIIDTFAYG</Hsp_hseq>
      <Hsp_midline>DL F+G++ + DPPR E + ++    +AGI V M+TGD  GTA AI + +GI         +E V+    TG +FD L  E+           AR  P  K ++++ L   + F  +T           MA +GIAMG +G+ V+K AS++VL+DDNFASI+ AVEEGR + +N+++F+  L++ NV +   ++L   L F +        L PV++LW+ +VT   PA  LG      D+M+RPP   + G+ +  +     A G</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>104.375</Hsp_bit-score>
      <Hsp_score>259</Hsp_score>
      <Hsp_evalue>2.18527e-23</Hsp_evalue>
      <Hsp_query-from>50</Hsp_query-from>
      <Hsp_query-to>829</Hsp_query-to>
      <Hsp_hit-from>112</Hsp_hit-from>
      <Hsp_hit-to>386</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>91</Hsp_identity>
      <Hsp_positive>145</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>291</Hsp_align-len>
      <Hsp_qseq>ERNAEGAIEALKEYEPEMGKVYRQDRRILQLVKARDLVPGDIVEIAVGDKVPADVRLTSIKSTTLRVDQSILTGESISVIKHTDAI--PDPRAVNQDKKNMLFSGTNIXXXXXXXXXXXXXXHTEIGKI------------RDAMVSTQQDK-----------------TPLQQKLDEFGKQLSKVISFVCVAVWLINIGHFSDPVHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFI</Hsp_qseq>
      <Hsp_hseq>EYKATKTMNSLKNLSSPNAHVIRNGKS--ETINSKDVVPGDICLVKVGDTIPADLRL--IETKNFDTDESLLTGESLPVSKDANLVFGKEEETSVGDRLNLAFSSSAVVKGRAKGIVIKTALNSEIGKIAKSLQGDSGLISRDPSKSWLQNTWISTKKVTGAFLGTNVGTPLHRKL----SKLAVLLFWIAVLFAIIVMASQKFDVDK----RVAIY----AICVALSMIPSSLVVVLTITMSVGAAVMVSRNVIVRKLDSLEALGAVNDICSDKTGTLTQGKMLARQIWI</Hsp_hseq>
      <Hsp_midline>E  A   + +LK        V R  +   + + ++D+VPGDI  + VGD +PAD+RL  I++     D+S+LTGES+ V K  + +   +      D+ N+ FS + +  GRA G+V+ T +++EIGKI            RD   S  Q+                  TPL +KL     +L+ ++ ++ V   +I +      V      R A+Y    A+ +A++ IP  L  V+T  +++G   M  +N IVR L S+E LG  + ICSDKTGTLT  +M   +++I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YGL006W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:485921:489442:1 gene:YGL006W transcript:YGL006W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PMC1 description:Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions; prevents growth inhibition by activation of calcineurin in the presence of elevated concentrations of calcium; similar to mammalian PMCA1a [Source:SGD;Acc:S000002974]</Hit_def>
  <Hit_accession>YGL006W</Hit_accession>
  <Hit_len>1173</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>137.117</Hsp_bit-score>
      <Hsp_score>344</Hsp_score>
      <Hsp_evalue>1.39597e-33</Hsp_evalue>
      <Hsp_query-from>1268</Hsp_query-from>
      <Hsp_query-to>1948</Hsp_query-to>
      <Hsp_hit-from>728</Hsp_hit-from>
      <Hsp_hit-to>971</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>84</Hsp_identity>
      <Hsp_positive>132</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>244</Hsp_align-len>
      <Hsp_qseq>LTFVGVVAMLDPPRREVSHSIALCREAGIRVMMITGDNKGTAVAICRRIGIFGEEENVEG-RAYTGREFDDLPVEQQRQAVQRACCFARVEPAHKSKIVQYLQSFNEITA-------------MAEIGIAMG-SGTAVAKSASEMVLADDNFASIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEA--LIPVQLLWVNLVTDGLPATALGFNPPDLDIMNRPPRSPKEGLIS</Hsp_qseq>
      <Hsp_hseq>LILDGLLGIQDPLRAGVRESVQQCQRAGVTVRMVTGDNILTAKAIARNCAILSTDISSEAYSAMEGTEFRKLTKNERIRILPNLRVLARSSPEDKRLLVETLKGMGDVVAVTGDGTNDAPALKLADVGFSMGISGTEVAREASDIILMTDDFSAIVNAIKWGRCVSVSIKKFIQFQLIVNITAVILTFVSSVASSDETSVLTAVQLLWINLIMDTLAALALATDKPDPNIMDRKPRGRSTSLIS</Hsp_hseq>
      <Hsp_midline>L   G++ + DP R  V  S+  C+ AG+ V M+TGDN  TA AI R   I   + + E   A  G EF  L   ++ + +      AR  P  K  +V+ L+   ++ A             +A++G +MG SGT VA+ AS+++L  D+F++IV A++ GR +  ++K+FI++ +  N+  V+  F+++     E   L  VQLLW+NL+ D L A AL  + PD +IM+R PR     LIS</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>104.375</Hsp_bit-score>
      <Hsp_score>259</Hsp_score>
      <Hsp_evalue>2.30391e-23</Hsp_evalue>
      <Hsp_query-from>110</Hsp_query-from>
      <Hsp_query-to>862</Hsp_query-to>
      <Hsp_hit-from>196</Hsp_hit-from>
      <Hsp_hit-to>473</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>94</Hsp_identity>
      <Hsp_positive>138</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>287</Hsp_align-len>
      <Hsp_qseq>VYRQDRRILQLVKARDLVPGDIVEIAVGDKVPADVRLTSIKSTTLRVDQSILTGESISVIK------------------HTDAIP-DPRAVNQDKKN----MLFSGTNIXXXXXXXXXXXXXXHTEIGKIRDAMVSTQQDKTPLQQKLDEFGKQLSK-------VISFVCVAVWLINI----GHFSD--PVHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDSVEGDSCSL</Hsp_qseq>
      <Hsp_hseq>VIRNDQEIL--ISIHHVLVGDVISLQTGDVVPADCVMISGKC---EADESSITGESNTIQKFPVDNSLRDFKKFNSIDSHNHSKPLDIGDVNEDGNKIADCMLISGSRILSGLGRGVITSVGINSVYGQTMTSL-NAEPESTPLQLHLSQLADNISVYGCVSAIILFLVLFTRYLFYIIPEDGRFHDLDPAQKGSKF---MNIFITSITVIVVAVPEGLPLAVTLALAFATTRMTKDGNLVRVLRSCETMGSATAVCSDKTGTLTENVMTVVRGFPGNSKFDDSKSL</Hsp_hseq>
      <Hsp_midline>V R D+ IL  +    ++ GD++ +  GD VPAD  + S K      D+S +TGES ++ K                  H  + P D   VN+D       ML SG+ I +G   GV+ + G+++  G+   ++ + + + TPLQ  L +    +S        ++  V    +L  I    G F D  P   GS     +  F  ++ + V A+PEGLP  +T  LA  T RM K   +VR L S ET+G  + +CSDKTGTLT N M+V R F  +S   DS SL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YGL008C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:479910:482666:-1 gene:YGL008C transcript:YGL008C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PMA1 description:Plasma membrane P2-type H+-ATPase; pumps protons out of cell; major regulator of cytoplasmic pH and plasma membrane potential; long-lived protein asymmetrically distributed at plasma membrane between mother cells and buds; accumulates at high levels in mother cells during aging, buds emerge with very low levels of Pma1p, newborn cells have low levels of Pma1p; Hsp30p plays a role in Pma1p regulation; interactions with Std1p appear to propagate [GAR+] [Source:SGD;Acc:S000002976]</Hit_def>
  <Hit_accession>YGL008C</Hit_accession>
  <Hit_len>918</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>98.9821</Hsp_bit-score>
      <Hsp_score>245</Hsp_score>
      <Hsp_evalue>8.44489e-22</Hsp_evalue>
      <Hsp_query-from>50</Hsp_query-from>
      <Hsp_query-to>862</Hsp_query-to>
      <Hsp_hit-from>162</Hsp_hit-from>
      <Hsp_hit-to>406</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>271</Hsp_align-len>
      <Hsp_qseq>ERNAEGAIEALKEYEPEMGKVYRQDRRILQLVKARDLVPGDIVEIAVGDKVPADVRLTSIKSTTLRVDQSILTGESISVIKHTDAIPDPRAVNQDKKNMLFSGTNIXXXXXXXXXXXXXXHTEIGKIRDAMVSTQQDKTPLQQKLDEFGKQLSKVISFVCVAVWLINIGHFSDPVHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDSVEGDSCSL</Hsp_qseq>
      <Hsp_hseq>EFQAGSIVDELKKTLANTAVVIR-DGQLVE-IPANEVVPGDILQLEDGTVIPTDGRIVT-EDCFLQIDQSAITGESLAVDKH-------------YGDQTFSSSTVKRGEGFMVVTATGDNTFVGRAAALVNKAAGGQGHFTEVLNGIGIILLVLVIATLLLVWTACFYR----------TNGIVRILRYTLGITIIGVPVGLPAVVTTTMAVGAAYLAKKQAIVQKLSAIESLAGVEILCSDKTGTLTKNKLSLHEPYTVEGVSPDDLML</Hsp_hseq>
      <Hsp_midline>E  A   ++ LK+       V R D ++++ + A ++VPGDI+++  G  +P D R+ + +   L++DQS +TGES++V KH               +  FS + +  G    VV ATG +T +G+    +      +    + L+  G  L  ++    + VW                  G V   +  + + +  +P GLPAV+TT +A+G   +AKK AIV+ L ++E+L    ++CSDKTGTLT N++S+   + ++ V  D   L</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>88.1965</Hsp_bit-score>
      <Hsp_score>217</Hsp_score>
      <Hsp_evalue>1.8537e-18</Hsp_evalue>
      <Hsp_query-from>1277</Hsp_query-from>
      <Hsp_query-to>1756</Hsp_query-to>
      <Hsp_hit-from>527</Hsp_hit-from>
      <Hsp_hit-to>697</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>173</Hsp_align-len>
      <Hsp_qseq>VGVVAMLDPPRREVSHSIALCREAGIRVMMITGDNKGTAVAICRRIGIFGEEENVEGRAYTGREFDDLPVEQQRQAVQRACCFARVEPAHKSKIVQYLQSFNEITAM-------------AEIGIAMGSGTAVAKSASEMVLADDNFASIVAAVEEGRAIYNNMKQFIRYLIS</Hsp_qseq>
      <Hsp_hseq>LGVMPCMDPPRDDTAQTVSEARHLGLRVKMLTGDAVGIAKETCRQLGLGTNIYNAERLGLGGGG--DMPGSELADFVENADGFAEVFPQHKYRVVEILQNRGYLVAMTGDGVNDAPSLKKADTGIAVEGATDAARSAADIVFLAPGLSAIIDALKTSRQIFHRMYSYVVYRIA</Hsp_hseq>
      <Hsp_midline>+GV+  +DPPR + + +++  R  G+RV M+TGD  G A   CR++G+     N E     G    D+P  +    V+ A  FA V P HK ++V+ LQ+   + AM             A+ GIA+   T  A+SA+++V      ++I+ A++  R I++ M  ++ Y I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YPL036W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:482843:485686:1 gene:YPL036W transcript:YPL036W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PMA2 description:Plasma membrane H+-ATPase; isoform of Pma1p, involved in pumping protons out of the cell; regulator of cytoplasmic pH and plasma membrane potential [Source:SGD;Acc:S000005957]</Hit_def>
  <Hit_accession>YPL036W</Hit_accession>
  <Hit_len>947</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>98.2117</Hsp_bit-score>
      <Hsp_score>243</Hsp_score>
      <Hsp_evalue>1.68082e-21</Hsp_evalue>
      <Hsp_query-from>50</Hsp_query-from>
      <Hsp_query-to>862</Hsp_query-to>
      <Hsp_hit-from>191</Hsp_hit-from>
      <Hsp_hit-to>435</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>137</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>271</Hsp_align-len>
      <Hsp_qseq>ERNAEGAIEALKEYEPEMGKVYRQDRRILQLVKARDLVPGDIVEIAVGDKVPADVRLTSIKSTTLRVDQSILTGESISVIKHTDAIPDPRAVNQDKKNMLFSGTNIXXXXXXXXXXXXXXHTEIGKIRDAMVSTQQDKTPLQQKLDEFGKQLSKVISFVCVAVWLINIGHFSDPVHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDSVEGDSCSL</Hsp_qseq>
      <Hsp_hseq>EFQAGSIVDELKKTLANTATVIR-DGQLIE-IPANEVVPGEILQLESGTIAPADGRIVT-EDCFLQIDQSAITGESLAAEKHYG-------------DEVFSSSTVKTGEAFMVVTATGDNTFVGRAAALVGQASGVEGHFTEVLNGIGIILLVLVIATLLLVW---TACFYRTV-------GIVSILRYTLGITIIGVPVGLPAVVTTTMAVGAAYLAKKQAIVQKLSAIESLAGVEILCSDKTGTLTKNKLSLHEPYTVEGVSPDDLML</Hsp_hseq>
      <Hsp_midline>E  A   ++ LK+       V R D ++++ + A ++VPG+I+++  G   PAD R+ + +   L++DQS +TGES++  KH               + +FS + +  G A  VV ATG +T +G+    +      +    + L+  G  L  ++    + VW      F   V       G V   +  + + +  +P GLPAV+TT +A+G   +AKK AIV+ L ++E+L    ++CSDKTGTLT N++S+   + ++ V  D   L</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>86.6557</Hsp_bit-score>
      <Hsp_score>213</Hsp_score>
      <Hsp_evalue>6.35201e-18</Hsp_evalue>
      <Hsp_query-from>1277</Hsp_query-from>
      <Hsp_query-to>1756</Hsp_query-to>
      <Hsp_hit-from>556</Hsp_hit-from>
      <Hsp_hit-to>726</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>173</Hsp_align-len>
      <Hsp_qseq>VGVVAMLDPPRREVSHSIALCREAGIRVMMITGDNKGTAVAICRRIGIFGEEENVEGRAYTGREFDDLPVEQQRQAVQRACCFARVEPAHKSKIVQYLQSFNEITAM-------------AEIGIAMGSGTAVAKSASEMVLADDNFASIVAAVEEGRAIYNNMKQFIRYLIS</Hsp_qseq>
      <Hsp_hseq>LGVMPCMDPPRDDTAQTINEARNLGLRIKMLTGDAVGIAKETCRQLGLGTNIYNAERLGLGGGG--DMPGSELADFVENADGFAEVFPQHKYRVVEILQNRGYLVAMTGDGVNDAPSLKKADTGIAVEGATDAARSAADIVFLAPGLSAIIDALKTSRQIFHRMYSYVVYRIA</Hsp_hseq>
      <Hsp_midline>+GV+  +DPPR + + +I   R  G+R+ M+TGD  G A   CR++G+     N E     G    D+P  +    V+ A  FA V P HK ++V+ LQ+   + AM             A+ GIA+   T  A+SA+++V      ++I+ A++  R I++ M  ++ Y I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YDR270W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1005675:1008689:1 gene:YDR270W transcript:YDR270W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CCC2 description:Cu(+2)-transporting P-type ATPase; required for export of copper from the cytosol into an extracytosolic compartment; similar to human proteins involved in Menkes and Wilsons diseases; protein abundance increases in response to DNA replication stress; affects TBSV model (+)RNA virus replication by regulating copper metabolism; human homologs ATP7A and ATP7B both complement yeast null mutant [Source:SGD;Acc:S000002678]</Hit_def>
  <Hit_accession>YDR270W</Hit_accession>
  <Hit_len>1004</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>7.63986e-09</Hsp_evalue>
      <Hsp_query-from>170</Hsp_query-from>
      <Hsp_query-to>838</Hsp_query-to>
      <Hsp_hit-from>435</Hsp_hit-from>
      <Hsp_hit-to>646</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>231</Hsp_align-len>
      <Hsp_qseq>DIVEIAVGDKVPADVRLTSIKSTTLRVDQSILTGESISVIKHTDAIPDPRAVNQDKKNMLFSGTNIXXXXXXXXXXXXXXHTEIGKIRDAMVSTQQDKTPLQQKLDEF------GKQLSKVISFVCVAVWLINIGHFSDPVHGGSWLRGAVYY--FKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDS</Hsp_qseq>
      <Hsp_hseq>DIVEIKPGMKIPADGIITRGES---EIDESLMTGESILVPKKT-GFPVIAGSVNGPGHFYFRTTTVGE------------ETKLANIIKVMKEAQLSKAPIQGYADYLASIFVPGILILAVLTFF-IWCFILNISA-NPPVAFTANTKADNFFICLQTATSVVIVACPCALGLATPTAIMVGTGVGAQNGVLIKGGEVLEKFNSITTFVFDKTGTLTTGFM-VVKKFLKDS</Hsp_hseq>
      <Hsp_midline>DIVEI  G K+PAD  +T  +S    +D+S++TGESI V K T   P          +  F  T +               T++  I   M   Q  K P+Q   D        G  +  V++F  +  +++NI   + PV   +  +   ++   + A ++ + A P  L     T + +GT   A+   +++    +E     +    DKTGTLTT  M V + F+ DS</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1480287417</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053884-RA transcript Note:&quot;Similar to Ash2l Set1/Ash2 histone methyltransferase complex subunit ASH2 (Mus musculus)&quot; offset:1 AED:0.13 eAED:0.13 QI:1|0.64|0.6|0.73|0.92|0.93|15|3188|572</Iteration_query-def>
  <Iteration_query-len>4908</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3425131311</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053886-RA transcript Note:&quot;Similar to TBC1D10B TBC1 domain family member 10B (Homo sapiens)&quot; offset:100 AED:0.53 eAED:0.53 QI:100|0.87|0.77|0.88|0.87|0.88|9|330|409</Iteration_query-def>
  <Iteration_query-len>1660</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YGR100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:690245:693097:1 gene:YGR100W transcript:YGR100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MDR1 description:Cytoplasmic GTPase-activating protein; activates Ypt/Rab transport GTPases Ypt6p, Ypt31p and Sec4p; involved in recycling of internalized proteins and regulation of Golgi secretory function [Source:SGD;Acc:S000003332]</Hit_def>
  <Hit_accession>YGR100W</Hit_accession>
  <Hit_len>950</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>122.865</Hsp_bit-score>
      <Hsp_score>307</Hsp_score>
      <Hsp_evalue>8.57463e-30</Hsp_evalue>
      <Hsp_query-from>260</Hsp_query-from>
      <Hsp_query-to>871</Hsp_query-to>
      <Hsp_hit-from>242</Hsp_hit-from>
      <Hsp_hit-to>445</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>206</Hsp_align-len>
      <Hsp_qseq>RKGIPPSLRARAWEHLSGSKYIMEQMPGKFEEL--DKLPGDPKWLEVIQKDLHRQFPFHELFRAKGGQGQQDLFRVLKAYTVYRPEEGYCQGQAPVAAVLLMHMPAEEAFWCFVQICEKYLPGYYSAGLESLQLDGEILFALLRKVSLIGYRHLKWHSVDPVLYMTEWFMCVFSRTLPWDSVLRVWDMFFCEGVKTMFRVGLVLLR</Hsp_qseq>
      <Hsp_hseq>RIGVPNRMRGEIWELCSGAMYMRYANSGEYERILNENAGKTSQAIDEIEKDLKRSLPEYSAYQTE--EGIQRLRNVLTAYSWKNPDVGYCQAMNIVVAGFLIFMSEEQAFWCLCNLCDIYVPGYYSKTMYGTLLDQRVFESFVEDRMPVLWEYILQHDIQLSVVSLPWFLSLFFTSMPLEYAVRIMDIFFMNGSITLFQVALAVLK</Hsp_hseq>
      <Hsp_midline>R G+P  +R   WE  SG+ Y+     G++E +  +      + ++ I+KDL R  P +  ++ +  +G Q L  VL AY+   P+ GYCQ    V A  L+ M  E+AFWC   +C+ Y+PGYYS  +    LD  +  + +     + + ++  H +   +    WF+ +F  ++P +  +R+ D+FF  G  T+F+V L +L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YOL112W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:106710:108188:1 gene:YOL112W transcript:YOL112W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MSB4 description:GTPase-activating protein of the Ras superfamily; acts primarily on Sec4p, localizes to the bud site and bud tip; msb3 msb4 double mutation causes defects in secretion and actin organization; similar to the TBC-domain Tre2 oncogene; MSB4 has a paralog, MSB3, that arose from the whole genome duplication; human homolog USP6NL can complement yeast msb3 msb4 double null mutant [Source:SGD;Acc:S000005472]</Hit_def>
  <Hit_accession>YOL112W</Hit_accession>
  <Hit_len>492</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>105.531</Hsp_bit-score>
      <Hsp_score>262</Hsp_score>
      <Hsp_evalue>1.19044e-24</Hsp_evalue>
      <Hsp_query-from>260</Hsp_query-from>
      <Hsp_query-to>871</Hsp_query-to>
      <Hsp_hit-from>145</Hsp_hit-from>
      <Hsp_hit-to>380</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>239</Hsp_align-len>
      <Hsp_qseq>RKGIPPSLRARAWEHLSGSKYIMEQMPGKFEELDKLPGD-------PKWLEVIQKDLHRQFPFHELFRAKGGQGQQ-----DLFRVLKAYTVYRPEEGYCQGQAPVAAVLLMHMPAEEAFWCFVQICEKYLPGYYSAGLESLQLDGEILFALLRKV-----SLIGYRHLKWH-SVDPV-----------------LYMTEWFMCVFSRTLPWDSVLRVWDMFFCEGVKTMFRVGLVLLR</Hsp_qseq>
      <Hsp_hseq>RKGIPAEWRGNAWWYFAGGQRQLDANVGVY---DRLKSDCREGAVSGKDMEAIERDLYRTFPDNIHFHKESFQNGEPAIIRSLRRVLMAFSVYDKTIGYCQSMNFLVGLLLLFMEEEKAFWMLVIITGKYLPGVYESDLEGANVDQGVLVLCIKEYLPEIWSHIESSYMNGNGSTDQISGPASGEEYLCRLPTLTLCTASWFMSCFVGVVPIETTLRIWDCLFYEESHFLFKVALGILK</Hsp_hseq>
      <Hsp_midline>RKGIP   R  AW + +G +  ++   G +   D+L  D        K +E I++DL+R FP +  F  +  Q  +      L RVL A++VY    GYCQ    +  +LL+ M  E+AFW  V I  KYLPG Y + LE   +D  +L   +++      S I   ++  + S D +                 L    WFM  F   +P ++ LR+WD  F E    +F+V L +L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YNL293W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:80640:82541:1 gene:YNL293W transcript:YNL293W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MSB3 description:Rab GTPase-activating protein; regulates endocytosis via inactivation of Vps21p at endosomes and vacuole fusion via inactivation of Ypt7p at vacuoles; also acts on Ypt52p and Sec4p; localizes to plasma membrane, sites of polarized growth; relocalizes from bud neck to cytoplasm upon DNA replication stress; similar to TBC-domain Tre2 oncogene; MSB3 has a paralog, MSB4, that arose from the whole genome duplication; human homolog USP6NL can complement yeast msb3 msb4 double null [Source:SGD;Acc:S000005237]</Hit_def>
  <Hit_accession>YNL293W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>97.0561</Hsp_bit-score>
      <Hsp_score>240</Hsp_score>
      <Hsp_evalue>1.00109e-21</Hsp_evalue>
      <Hsp_query-from>239</Hsp_query-from>
      <Hsp_query-to>871</Hsp_query-to>
      <Hsp_hit-from>214</Hsp_hit-from>
      <Hsp_hit-to>469</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>256</Hsp_align-len>
      <Hsp_qseq>KKVKLRCRKGIPPSLRARAW-------EHLSGSKYIMEQMPGKFEELDKLPGDPKW---LEVIQKDLHRQFPFHELFRA-----KGGQGQQDLFRVLKAYTVYRPEEGYCQGQAPVAAVLLMHMPAEEAFWCFVQICEKYLPGYYSAGLESLQLDGEIL----------------------------FALLRKVSLIGYRHLKW-HSVDPVLYMT-EWFMCVFSRTLPWDSVLRVWDMFFCEGVKTMFRVGLVLLR</Hsp_qseq>
      <Hsp_hseq>ERLKRYVRKGIPAEWRGNAWWHFARGQEKLNKNKGVYSQLLRKMKQIKKQNPNEKQVQDLDIIERDLNRTFPDNIHFQSSLHNKEGPPIIKSLRRVLVAFSLYNPKIGYCQSMNFLAGLLLLFLDEERAFWMLVIITSRYLPGVHNINLEGVNIDQGVLMLCVKEYIPEVWSYIKPSIDHHQKNNKTFSPSNKKVLFNMQKNEFLYRLPPITLCTASWFMSCFVGVVPIETTLRIWDCLFYEESHFLFKVSLAVLK</Hsp_hseq>
      <Hsp_midline>+++K   RKGIP   R  AW       E L+ +K +  Q+  K +++ K   + K    L++I++DL+R FP +  F++     +G    + L RVL A+++Y P+ GYCQ    +A +LL+ +  E AFW  V I  +YLPG ++  LE + +D  +L                            F+   K  L   +  ++ + + P+   T  WFM  F   +P ++ LR+WD  F E    +F+V L +L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YPL249C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:76669:79353:-1 gene:YPL249C transcript:YPL249C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GYP5 description:GTPase-activating protein (GAP) for yeast Rab family members; involved in ER to Golgi trafficking; exhibits GAP activity toward Ypt1p that is stimulated by Gyl1p, also acts on Sec4p; interacts with Gyl1p, Rvs161p and Rvs167p; involved in recruiting Rvs167p to the bud tip during polarized growth; relocalizes from bud neck to cytoplasm upon DNA replication stress; GYP5 has a paralog, GYL1, that arose from the whole genome duplication [Source:SGD;Acc:S000006170]</Hit_def>
  <Hit_accession>YPL249C</Hit_accession>
  <Hit_len>894</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.8113</Hsp_bit-score>
      <Hsp_score>216</Hsp_score>
      <Hsp_evalue>1.11276e-18</Hsp_evalue>
      <Hsp_query-from>191</Hsp_query-from>
      <Hsp_query-to>868</Hsp_query-to>
      <Hsp_hit-from>426</Hsp_hit-from>
      <Hsp_hit-to>642</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>233</Hsp_align-len>
      <Hsp_qseq>WLEMLRYWDKWITKGYKKVKLRCRKGIPPSLRARAWEHLSGSKYIMEQMPGKFEELDKLPGDPKWLEVIQKDLHRQFPFHELFRAKGGQGQQDLFRVLKAYTVYRPEEGYCQGQAPVAAVLLMHMPAE-EAFWCFVQICEKY------LPGYYSAGLESLQLDGEILFALLRKVSLIGYRHLKWHSVDPVLYMTEWFMCVFSRTLPWDSVLRVWDMFFCEGVKTMFRVGLVLL</Hsp_qseq>
      <Hsp_hseq>WTQVVNDYATVASNEPENLEAHVTNGIPPQIRGIIWQLMANSKS--REMEDIYETL--LDTECLHEATIRRDLRRT-----KFVAE--DKMESLYKVIKVYSVYDPDVGYTQGMGFIAAPLLINCENEAESFGLLVGLMKNYGLRELFLPGMPGLMLMLYQFD-----RLLEEHSPSLYNRLIREGISSTMYATQWFLTFFAYKFPLEFVLRIFDIVFVEGIEVLLKFAVNLM</Hsp_hseq>
      <Hsp_midline>W +++  +    +   + ++     GIPP +R   W+ ++ SK    +M   +E L  L  +      I++DL R       F A+     + L++V+K Y+VY P+ GY QG   +AA LL++   E E+F   V + + Y      LPG     L   Q D      LL + S   Y  L    +   +Y T+WF+  F+   P + VLR++D+ F EG++ + +  + L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YMR055C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:386101:387021:-1 gene:YMR055C transcript:YMR055C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BUB2 description:Mitotic exit network regulator; forms GTPase-activating Bfa1p-Bub2p complex that binds Tem1p and spindle pole bodies, blocks cell cycle progression before anaphase in response to spindle and kinetochore damage [Source:SGD;Acc:S000004659]</Hit_def>
  <Hit_accession>YMR055C</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>2.0883e-07</Hsp_evalue>
      <Hsp_query-from>284</Hsp_query-from>
      <Hsp_query-to>892</Hsp_query-to>
      <Hsp_hit-from>43</Hsp_hit-from>
      <Hsp_hit-to>258</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>220</Hsp_align-len>
      <Hsp_qseq>RARAWEHLSGSKYIMEQMPGKFEELDKL-PGDPKWLEVIQKDLHRQFPFHELFRAKGGQGQQDLFRVLKAY---TVYR---------PEEGYCQGQAPVAAVLLMHMPAEE-AFWCFVQICEKYLPGYYSAGLESLQLDGEILFALLRKVSLIGYRHLKWHSVDPVLYMTEWFMCVFSRTLPWDSVLRVWDMFFCEG--VKTMFRVG-LVLLRHALGNSE</Hsp_qseq>
      <Hsp_hseq>RCYVWTVLSQTS--MEASTQRYLALLKLGPPSTTIYQKIKNDTSRTFQTDPNFRNRVSEDA--LIRCLSCFAWQTQQRRQKTRFGRIPVSTYVQGMNVLLAPLLYSCPSEPMAYQLFTKLCYEMIPTYLTKNLNGAQNGAKLLDISLRIIDPKLSKFLSDNLLTAEIYGMPSILTLSSCNKPLDQVIKLWDFMFAYGFHMNILFVVAFLVKMRSKVFKSD</Hsp_hseq>
      <Hsp_midline>R   W  LS +   ME    ++  L KL P      + I+ D  R F     FR +  +    L R L  +   T  R         P   Y QG   + A LL   P+E  A+  F ++C + +P Y +  L   Q   ++L   LR +     + L  + +   +Y     + + S   P D V+++WD  F  G  +  +F V  LV +R  +  S+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YMR192W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:647118:649280:1 gene:YMR192W transcript:YMR192W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GYL1 description:Putative GTPase activating protein (GAP) with a role in exocytosis; stimulates Gyp5p GAP activity on Ypt1p, colocalizes with Gyp5p at sites of polarized growth; interacts with Gyp5p, Rvs161p, and Rvs167p; involved in recruiting Rvs167p to the bud tip during polarized growth; increases in abundance and relocalizes from bud neck to cytoplasm upon DNA replication stress; GYL1 has a paralog, GYP5, that arose from the whole genome duplication [Source:SGD;Acc:S000004804]</Hit_def>
  <Hit_accession>YMR192W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>1.98958e-06</Hsp_evalue>
      <Hsp_query-from>191</Hsp_query-from>
      <Hsp_query-to>877</Hsp_query-to>
      <Hsp_hit-from>272</Hsp_hit-from>
      <Hsp_hit-to>492</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>249</Hsp_align-len>
      <Hsp_qseq>WLEMLRYWDKWITKGYKKVKLRCRKGIPPSLRARAWEHLSGSK----------YIMEQMPGKFEELDKLPGDPKWLEVIQKDLHRQFPFHELFRAKGGQGQQDLFRVLKAYTVYRPEEGYCQGQAPVAAVLLMHMPAEE----AFWCFVQICEKY------LPGYYSAGLESLQLDGEILFALLRKVSLIGYRHLKWHSVDPVLYMTEWFMCVFSRTLPWDSVLRVWDMFFCEGVKTMFRVGLVLLRHA</Hsp_qseq>
      <Hsp_hseq>WLKVIGDYQNILINDIETLHFQLSRGIPAAYRLVVWQLVSYAKSKSFDPIYETYLTEMAPFDVQEFEN-----------QLKMMDEVPSEYVKR---------ISNVLKAYLLFDPE---CEFSTDIAYIINMILDVCEEEANAFGLLVRLMKVYGLRLLFLPSASEIDILCYKFD-----RLVEEFYPEIHNHMVEKGVRSSMFLPGFFTTLFQKKLPTEIQPRIGDMVFLEGIDSIMRILATLLSNS</Hsp_hseq>
      <Hsp_midline>WL+++  +   +    + +  +  +GIP + R   W+ +S +K          Y+ E  P   +E +            Q  +  + P   + R         +  VLKAY ++ PE   C+    +A ++ M +   E    AF   V++ + Y      LP      +   + D      L+ +     + H+    V   +++  +F  +F + LP +   R+ DM F EG+ ++ R+   LL ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1047476686</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053887-RA transcript Note:&quot;Similar to Ankfy1 Rabankyrin-5 (Mus musculus)&quot; offset:0 AED:0.05 eAED:0.07 QI:0|0.21|0.20|1|1|1|24|3011|1131</Iteration_query-def>
  <Iteration_query-len>6407</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDR264C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:996029:998323:-1 gene:YDR264C transcript:YDR264C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AKR1 description:Palmitoyl transferase involved in protein palmitoylation; acts as a negative regulator of pheromone response pathway; required for endocytosis of pheromone receptors; involved in cell shape control; contains ankyrin repeats; AKR1 has a paralog, AKR2, that arose from the whole genome duplication; any of several human homologs encoding DHHC-type zinc fingers (ZDHHC) can complement temperature sensitivity of yeast akr1 null mutant [Source:SGD;Acc:S000002672]</Hit_def>
  <Hit_accession>YDR264C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>1.39088e-09</Hsp_evalue>
      <Hsp_query-from>2365</Hsp_query-from>
      <Hsp_query-to>3174</Hsp_query-to>
      <Hsp_hit-from>111</Hsp_hit-from>
      <Hsp_hit-to>379</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>114</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>294</Hsp_align-len>
      <Hsp_qseq>TPLHIAISNQHDVIIALLLSH---PELRLGARDRQGQTPFACAMTYKNNRAADAILKR--EPTAAEQVDNKGRNFLHVAVQNSDIESVLFLISVSANVNSR------VQDSTGLTPLHLATQGGSEIIVRNLLLAGANVRELTKNRQTALHLAAQLDLPSICSVLIENSTDFSACDDNGNNALHLAVMHGRLNVVRVLLTESSIDAEAFNLRGQ-------------SPMHVLGQYGKENAAAIFELFLECMPEYPLDKPDIEGHTVLLLAYMKGNGNLCRAVVRAGARLGLTN</Hsp_qseq>
      <Hsp_hseq>TGLHWASINNRLSVVDFLVSQGADVNARAGALH---ATPLHWAARYGYVYIVDFLLKHGADPT---MTDDQGFNLLHLSVNSSNIMLVLYVL---FNVVSKGLLDIDCRDPKGRTSLLWAAYQGDSLTVAELLKFGASIKIADTEGFTPLHWGTVKGQPHVLKYLIQDGADFFQKTDTGKDCFAIAQEMNTVYSLREALTHSGFDYHGYPIKKWFKKSQHAKLVTFITPFLFLG--------IAFALFSHINPLFVI--------IVLFLLAIATNKGLNKFVLPSYGRMGVHN</Hsp_hseq>
      <Hsp_midline>T LH A  N    ++  L+S       R GA      TP   A  Y      D +LK   +PT     D++G N LH++V +S+I  VL+++    NV S+       +D  G T L  A   G  + V  LL  GA+++       T LH       P +   LI++  DF    D G +   +A     +  +R  LT S  D   + ++               +P   LG          F LF    P + +         VL L  +  N  L + V+ +  R+G+ N</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YGR232W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:953960:954646:1 gene:YGR232W transcript:YGR232W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NAS6 description:Evolutionarily conserved 19S regulatory particle assembly-chaperone; proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); ortholog of human oncoprotein gankyrin, also known as p28, which interacts with the Rb tumor suppressor and CDK4/6 [Source:SGD;Acc:S000003464]</Hit_def>
  <Hit_accession>YGR232W</Hit_accession>
  <Hit_len>228</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>6.3985e-08</Hsp_evalue>
      <Hsp_query-from>2518</Hsp_query-from>
      <Hsp_query-to>3027</Hsp_query-to>
      <Hsp_hit-from>21</Hsp_hit-from>
      <Hsp_hit-to>193</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>176</Hsp_align-len>
      <Hsp_qseq>ILKREPTAAEQVDNKGRNFLHVAVQNSDIESVLFLISVSANVN-SRVQDSTGLTPLHLATQGGSEIIVRNLL--LAGANVRELTKNRQTALHLAAQLDLPSICSVLIENSTDFSACDDNGNNALHLAVMHGRLNVVRVL--LTESSIDAEAFNLRGQSPM-HVLGQYGKENAAAIF</Hsp_qseq>
      <Hsp_hseq>LLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQ--DKQGWTPLFHALAE-GHGDAAVLL</Hsp_hseq>
      <Hsp_midline>+L  +P+   Q D  GR  LH +V     E   FL+S   NVN     D +G TP H+A   G+  +V++L       ++ ++T    T LHLA       +   LIEN       D      LH A   G L ++ +L  L +S+++ +  + +G +P+ H L + G  +AA + </Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>6.26585e-06</Hsp_evalue>
      <Hsp_query-from>2011</Hsp_query-from>
      <Hsp_query-to>2589</Hsp_query-to>
      <Hsp_hit-from>32</Hsp_hit-from>
      <Hsp_hit-to>216</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>196</Hsp_align-len>
      <Hsp_qseq>RTAEGQTPLQLAIRQQLPLVVDALCTRGADMTVRHGCDSTCWGPGPGGCQQTLLHRAIDENNEKIACFLIRRRPGLKGEGQEEARDGQTPLHLAATWGLEEVVQCLLEYRANVNMQGR---TPLHIAISNQHDVIIALLLSHPELRLGARDRQGQTPFACAMTYKNNRAADAILKREPTAAEQVDNKGRNFLHVAV</Hsp_qseq>
      <Hsp_hseq>KDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTP---------FHIACSVGNLEVVKSLYDRP--LKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEKYGAEYDLVDNKGAKAEDVAL</Hsp_hseq>
      <Hsp_midline>+  +G+ PL  ++  Q   +   L ++  ++ +    D + W P          H A    N ++   L  R   LK +  +    G T LHLA      EV Q L+E  A+V ++ +    PLH A S     +I LL    +  +  +D+QG TP   A+   +  AA  ++++     + VDNKG     VA+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>105</Statistics_hsp-len>
      <Statistics_eff-space>4508766010</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053891-RA transcript Note:&quot;Similar to Rabep1 Rab GTPase-binding effector protein 1 (Rattus norvegicus)&quot; offset:202 AED:0.10 eAED:0.11 QI:202|0.68|0.82|1|0.87|0.94|17|1724|690</Iteration_query-def>
  <Iteration_query-len>3999</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2768879344</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0016414-RA transcript Note:&quot;Similar to ATXN2 Ataxin-2 (Homo sapiens)&quot; offset:505 AED:0.19 eAED:0.19 QI:505|0.5|0.47|1|0.05|0.10|19|2030|776</Iteration_query-def>
  <Iteration_query-len>4866</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3393851573</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0016033-RA transcript Note:&quot;Similar to mybbp1a Myb-binding protein 1A-like protein (Danio rerio)&quot; offset:0 AED:0.18 eAED:0.21 QI:0|0.72|0.73|1|0.76|0.80|26|221|1219</Iteration_query-def>
  <Iteration_query-len>3881</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2678980664</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0030289-RA transcript Note:&quot;Similar to qprt Nicotinate-nucleotide pyrophosphorylase [carboxylating] (Fragment) (Nematostella vectensis)&quot; offset:0 AED:0.14 eAED:0.14 QI:0|0.66|0.25|1|0.33|0.75|4|850|242</Iteration_query-def>
  <Iteration_query-len>1579</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YFR047C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:244279:245166:-1 gene:YFR047C transcript:YFR047C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BNA6 description:Quinolinate phosphoribosyl transferase; required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p [Source:SGD;Acc:S000001943]</Hit_def>
  <Hit_accession>YFR047C</Hit_accession>
  <Hit_len>295</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>181.415</Hsp_bit-score>
      <Hsp_score>459</Hsp_score>
      <Hsp_evalue>1.57395e-53</Hsp_evalue>
      <Hsp_query-from>28</Hsp_query-from>
      <Hsp_query-to>600</Hsp_query-to>
      <Hsp_hit-from>92</Hsp_hit-from>
      <Hsp_hit-to>295</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>104</Hsp_identity>
      <Hsp_positive>142</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>204</Hsp_align-len>
      <Hsp_qseq>VAVVTGKARHLLLAERPALNCLARASGVXXXXXXXXXXXXXXGWAGQVAGTRKTTPGFRLVEKHALLVGGAATHRYDLSSMIMLKDNHVWSSGGITQAVRDAKRVGGFSLKVEVECRTLXXXXXXXXXXXDVIMLDNVA-------------PPSEFPTVVVEASGGVTDENLLRYLGPSVDIVSLGSLTQGYPVVDFSLKVSR</Hsp_qseq>
      <Hsp_hseq>VAKITGPAKNILLAERTALNILSRSSGIATASHKIISLARSTGYKGTIAGTRKTTPGLRRLEKYSMLVGGCDTHRYDLSSMVMLKDNHIWATGSITNAVKNARAVCGFAVKIEVECLSEDEATEAIEAGADVIMLDNFKGDGLKMCAQSLKNKWNGKKHFLLECSGGLNLDNLEEYLCDDIDIYSTSSIHQGTPVIDFSLKLAH</Hsp_hseq>
      <Hsp_midline>VA +TG A+++LLAER ALN L+R+SG+ATA+ +    AR+ G+ G +AGTRKTTPG R +EK+++LVGG  THRYDLSSM+MLKDNH+W++G IT AV++A+ V GF++K+EVEC + +E  EA  AGADVIMLDN                 +     ++E SGG+  +NL  YL   +DI S  S+ QG PV+DFSLK++ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>990864144</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053895-RA transcript Note:&quot;Similar to nxn Nucleoredoxin (Danio rerio)&quot; offset:233 AED:0.04 eAED:0.04 QI:233|1|1|1|0.66|0.57|7|1376|238</Iteration_query-def>
  <Iteration_query-len>2326</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1541681826</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053896-RA transcript Note:&quot;Similar to TEX14 Inactive serine/threonine-protein kinase TEX14 (Homo sapiens)&quot; offset:30 AED:0.24 eAED:0.24 QI:30|0.64|0.77|0.94|0.70|0.66|18|1872|906</Iteration_query-def>
  <Iteration_query-len>4623</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3212875946</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053898-RA transcript Note:&quot;Similar to Ankrd13d Ankyrin repeat domain-containing protein 13D (Mus musculus)&quot; offset:96 AED:0.12 eAED:0.12 QI:96|0.92|0.92|1|0.76|0.78|14|2129|628</Iteration_query-def>
  <Iteration_query-len>4112</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>102</Statistics_hsp-len>
      <Statistics_eff-space>2841419356</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053899-RA transcript Note:&quot;Similar to BOLA2 BolA-like protein 2 (Homo sapiens)&quot; offset:134 AED:0.06 eAED:0.06 QI:134|1|1|1|1|1|3|1118|87</Iteration_query-def>
  <Iteration_query-len>1516</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YGL220W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:82374:82736:1 gene:YGL220W transcript:YGL220W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Cytosolic protein involved in repression of iron regulon transcription; forms an iron-independent complex with Fra1p, Grx3p, and Grx4p; null mutant fails to repress the iron regulon and is sensitive to nickel; sequence similarity to human BOLA family member, BOLA2 [Source:SGD;Acc:S000003188]</Hit_def>
  <Hit_accession>YGL220W</Hit_accession>
  <Hit_len>120</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>5.97571e-14</Hsp_evalue>
      <Hsp_query-from>141</Hsp_query-from>
      <Hsp_query-to>380</Hsp_query-to>
      <Hsp_hit-from>38</Hsp_hit-from>
      <Hsp_hit-to>117</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>81</Hsp_align-len>
      <Hsp_qseq>ITAEALKQKLEKELDASY-VEVDDISPTMCGASFKVLVVSSKFEGKPLLQRHRLVNAALAEELKEIHAFQQKTLTPEQWQQ</Hsp_qseq>
      <Hsp_hseq>VTEQGLRERIESAIPQVYHIIVTDLSYG-CGQSFDIVVVSDFFQGKSKLMRSRAVNKAVKEELQEIHAFSCKCYTEEEWSK</Hsp_hseq>
      <Hsp_midline>+T + L++++E  +   Y + V D+S   CG SF ++VVS  F+GK  L R R VN A+ EEL+EIHAF  K  T E+W +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YAL046C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:57029:57385:-1 gene:YAL046C transcript:YAL046C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BOL3 description:Protein involved in Fe-S cluster transfer to mitochondrial clients; protects [4Fe-4S] clusters from damage due to oxidative stress by acting along with Nfu1p at a late step in the transfer of [4Fe-4S] clusters from the ISA complex to mitochondrial client proteins like lipoate synthase and succinate dehydrogenase; sequence similarity to human BOLA family member, BOLA3, mutations of which are associated with Multiple Mitochondria Dysfunctions Syndrome (MMDS2) [Source:SGD;Acc:S000000044]</Hit_def>
  <Hit_accession>YAL046C</Hit_accession>
  <Hit_len>118</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>7.90696e-08</Hsp_evalue>
      <Hsp_query-from>165</Hsp_query-from>
      <Hsp_query-to>356</Hsp_query-to>
      <Hsp_hit-from>45</Hsp_hit-from>
      <Hsp_hit-to>107</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>38</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>64</Hsp_align-len>
      <Hsp_qseq>KLEKELDASYVEVDDISPTMCGASFKVLVVSSKFEGKPLLQRHRLVNAALAEELKEIHAFQQKT</Hsp_qseq>
      <Hsp_hseq>KLQQELEPEVCKVQDVSGG-CGSMFAINITSKKFNGLSLIKQHQLVNRILRDDISRWHGLQLTT</Hsp_hseq>
      <Hsp_midline>KL++EL+    +V D+S   CG+ F + + S KF G  L+++H+LVN  L +++   H  Q  T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>942697137</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

