<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0055103-RA transcript Note:&quot;Similar to SPTB Spectrin beta chain, erythrocytic (Homo sapiens)&quot; offset:0 AED:0.13 eAED:0.13 QI:0|0|0|0.82|1|1|28|0|1738</BlastOutput_query-def>
  <BlastOutput_query-len>5217</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055103-RA transcript Note:&quot;Similar to SPTB Spectrin beta chain, erythrocytic (Homo sapiens)&quot; offset:0 AED:0.13 eAED:0.13 QI:0|0|0|0.82|1|1|28|0|1738</Iteration_query-def>
  <Iteration_query-len>5217</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3655260812</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055105-RA transcript Note:&quot;Similar to s100a1 Protein S100-A1 (Misgurnus fossilis)&quot; offset:71 AED:0.25 eAED:0.25 QI:71|1|1|1|0.5|0.33|3|318|108</Iteration_query-def>
  <Iteration_query-len>716</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>87</Statistics_hsp-len>
      <Statistics_eff-space>353319917</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055106-RA transcript Note:&quot;Similar to s100a1 Protein S100-A1 (Misgurnus fossilis)&quot; offset:67 AED:0.25 eAED:0.25 QI:67|1|1|1|0.5|0.33|3|308|108</Iteration_query-def>
  <Iteration_query-len>702</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>87</Statistics_hsp-len>
      <Statistics_eff-space>343960449</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055107-RA transcript Note:&quot;Similar to Actg2 Actin, gamma-enteric smooth muscle (Rattus norvegicus)&quot; offset:0 AED:0.27 eAED:0.28 QI:0|0.6|0.33|1|1|1|6|0|328</Iteration_query-def>
  <Iteration_query-len>987</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YFL039C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:53260:54696:-1 gene:YFL039C transcript:YFL039C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ACT1 description:Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions [Source:SGD;Acc:S000001855]</Hit_def>
  <Hit_accession>YFL039C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>582.022</Hsp_bit-score>
      <Hsp_score>1499</Hsp_score>
      <Hsp_evalue>0</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>984</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>375</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>279</Hsp_identity>
      <Hsp_positive>304</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>374</Hsp_align-len>
      <Hsp_qseq>DEETTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQ------------------SKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRIAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMTMAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTI------------------------------KYSVWIGGSILASLSTFQQMWISKPEYDEAGPSIVHRKCF</Hsp_qseq>
      <Hsp_hseq>DSEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGIMVGMGQKDSYVGDEAQSKRGILTLRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPMNPKSNREKMTQIMFETFNVPAFYVSIQAVLSLYSSGRTTGIVLDSGDGVTHVVPIYAGFSLPHAILRIDLAGRDLTDYLMKILSERGYSFSTTAEREIVRDIKEKLCYVALDFEQEMQTAAQSSSIEKSYELPDGQVITIGNERFRAPEALFHPSVLGLESAGIDQTTYNSIMKCDVDVRKELYGNIVMSGGTTMFPGIAERMQKEITALAPSSMKVKIIAPPERKYSVWIGGSILASLTTFQQMWISKQEYDESGPSIVHHKCF</Hsp_hseq>
      <Hsp_midline>D E  ALV DNGSG+CKAGFAGDDAPRAVFPSIVGRPRHQ                  SKRGILTL+YPIEHGI+TNWDDMEKIWHH+FYNELR+APEEHP LLTEAP+NPK+NREKMTQIMFETFNVPA YV+IQAVLSLY+SGRTTGIVLDSGDGVTH VPIY G++LPHAI+R+DLAGRDLTDYLMKIL+ERGYSF TTAEREIVRDIKEKLCYVALDFE EM  AA SSS+EKSYELPDGQVITIGNERFR PE LF PS +G+ESAGI +TTYNSIMKCD+D+RK+LY N V+SGGTT+                              KYSVWIGGSILASL+TFQQMWISK EYDE+GPSIVH KCF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YDL029W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:399340:400638:1 gene:YDL029W transcript:YDL029W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ARP2 description:Essential component of the Arp2/3 complex; Arp2/3 is a highly conserved actin nucleation center required for the motility and integrity of actin patches; involved in endocytosis and membrane growth and polarity; required for efficient Golgi-to-ER trafficking in COPI mutants [Source:SGD;Acc:S000002187]</Hit_def>
  <Hit_accession>YDL029W</Hit_accession>
  <Hit_len>391</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>302.753</Hsp_bit-score>
      <Hsp_score>774</Hsp_score>
      <Hsp_evalue>8.46067e-102</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>963</Hsp_query-to>
      <Hsp_hit-from>7</Hsp_hit-from>
      <Hsp_hit-to>383</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>156</Hsp_identity>
      <Hsp_positive>223</Hsp_positive>
      <Hsp_gaps>64</Hsp_gaps>
      <Hsp_align-len>377</Hsp_align-len>
      <Hsp_qseq>LVCDNGSGLCKAGFAGDDAPRAVFPSIVGRP--RHQSK-------------------RGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRIAPEEH-PTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMTMAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTI-----------------------------------------KYSVWIGGSILAS-LSTFQQMWISKPEYDEAGPS</Hsp_qseq>
      <Hsp_hseq>IVLDQGTGFVKIGRAGENFPDYTFPSIVGRPILRAEERASVATPLKDIMIGDEASEVRSYLQISYPMENGIIKNWTDMELLWDYAFFEQMKLPSTSNGKILLTEPPMNPLKNREKMCEVMFEKYDFGGVYVAIQAVLALYAQGLSSGVVVDSGDGVTHIVPVYESVVLSHLTRRLDVAGRDVTRHLIDLLSRRGYAFNRTADFETVRQIKEKLCYVSYDLDLDTKLARETTALVESYELPDGRTIKVGQERFEAPECLFQPGLVDVEQPGVGELLFNTVQSADVDIRSSLYKAIVLSGGSSMYPGLPSRLEKELKQLWFSRVLHNDPSRLDKFKVRIEDPPRRKHMVFIGGAVLASIMADKDHMWLSKQEWQESGPS</Hsp_hseq>
      <Hsp_midline>+V D G+G  K G AG++ P   FPSIVGRP  R + +                   R  L + YP+E+GII NW DME +W ++F+ ++++    +   LLTE P+NP  NREKM ++MFE ++   +YVAIQAVL+LYA G ++G+V+DSGDGVTH VP+YE   L H   RLD+AGRD+T +L+ +L+ RGY+F  TA+ E VR IKEKLCYV+ D + +  +A  +++L +SYELPDG+ I +G ERF  PE LFQP  + +E  G+ E  +N++   D+DIR  LY   VLSGG+++                                         K+ V+IGG++LAS ++    MW+SK E+ E+GPS</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YHR129C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:362999:364153:-1 gene:YHR129C transcript:YHR129C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ARP1 description:Actin-related protein of the dynactin complex; required for spindle orientation and nuclear migration; forms actin-like short filament composed of 9 or 10 Arp1p monomers; putative ortholog of mammalian centractin [Source:SGD;Acc:S000001171]</Hit_def>
  <Hit_accession>YHR129C</Hit_accession>
  <Hit_len>384</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>295.434</Hsp_bit-score>
      <Hsp_score>755</Hsp_score>
      <Hsp_evalue>6.43171e-99</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>951</Hsp_query-to>
      <Hsp_hit-from>15</Hsp_hit-from>
      <Hsp_hit-to>374</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>151</Hsp_identity>
      <Hsp_positive>219</Hsp_positive>
      <Hsp_gaps>51</Hsp_gaps>
      <Hsp_align-len>360</Hsp_align-len>
      <Hsp_qseq>LVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRH------------------QSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRIAP-EEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYL-MKILTERGYSFVTTAEREIVRDIKEKLCYVALDFEN-EMTMAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTI------------------------------KYSVWIGGSILASLSTFQQMWISKPEYDE</Hsp_qseq>
      <Hsp_hseq>VVIDNGSGIIKAGFSGEERPKALEYCLVGNTKYDKVMLEGLQGDTFIGNNAQKLRGLLKLRYPIKHGVVEDWDSMELIWSYVLNEVLQLQNIGEHPLLITEAPMNPLKNREQMAQVLFETFDVSALYVSNPAVLSLYASGRTTGCVVDCGEGYCSTVPIYDGFALPASMMRMDIGGADITEQLQFQLRKSAGVSLFSSSEREIVRTMKEKVCYLAKNIKKEEEKYLQGTQDLISTFKLPDGRCIEVGNDRYRAPEILFSPQIIGLGYDGLSDMCMQSIWKVDLDLRKPLLSSIILSGGTTTLKGFGDRMLWDLEALTKGTSKIKIIAPSERKYTTWIGGSILTGLSTFQRLWTKKSDWLE</Hsp_hseq>
      <Hsp_midline>+V DNGSG+ KAGF+G++ P+A+   +VG  ++                  Q  RG+L L+YPI+HG++ +WD ME IW +     L++    EHP L+TEAP+NP  NRE+M Q++FETF+V A+YV+  AVLSLYASGRTTG V+D G+G    VPIY+G+ALP ++MR+D+ G D+T+ L  ++    G S  +++EREIVR +KEK+CY+A + +  E      +  L  +++LPDG+ I +GN+R+R PE LF P  IG+   G+ +    SI K D+D+RK L ++ +LSGGTT                               KY+ WIGGSIL  LSTFQ++W  K ++ E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YJR065C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:557809:559158:-1 gene:YJR065C transcript:YJR065C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ARP3 description:Essential component of the Arp2/3 complex; Arp2/3 is a highly conserved actin nucleation center required for the motility and integrity of actin patches; involved in endocytosis and membrane growth and polarity [Source:SGD;Acc:S000003826]</Hit_def>
  <Hit_accession>YJR065C</Hit_accession>
  <Hit_len>449</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>198.749</Hsp_bit-score>
      <Hsp_score>504</Hsp_score>
      <Hsp_evalue>1.31228e-60</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>972</Hsp_query-to>
      <Hsp_hit-from>8</Hsp_hit-from>
      <Hsp_hit-to>441</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>147</Hsp_identity>
      <Hsp_positive>200</Hsp_positive>
      <Hsp_gaps>127</Hsp_gaps>
      <Hsp_align-len>439</Hsp_align-len>
      <Hsp_qseq>ALVCDNGSGLCKAGFAGDDAPRAVFP--------------SIVGRPRHQS-----------------------------KRGI-------------------LTLKYPIEHGIITNWDDMEKIWHHSFYNELRIAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRT--------TGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVT--TAEREIVRDIKEKLCYVALDFENEMTMAASSSS-----LEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYN-SIMKCDIDIRKDLYANNVLSGGTTI--------------------------------------------KYSVWIGGSILASLSTFQQMWISKPEYDEAGPSIVH</Hsp_qseq>
      <Hsp_hseq>AVVMDNGTGLTKLGFAGNDSPSWVFPTAIATAAPSNTKKSSGVGAPSAVSNEASYFGNSTSATNFNGATGGLLSNNLSGKRGTEDLDFYIGNEALVASQGPSYSLSYPIRHGQVENWDHMERFWENSIFKYLRTEPEDHFFLLTEPPLNPPENREQVAEIFFESFNCAGLYIAVQAVLALAASWTSSKVTDRSLTGTVIDSGDGVTHVIPVAEGYVIGSAIKNIPIAGRDITLFIQSLLRERGEADTSLRTAEK-----IKQEYCYVCPDIVKEFNKFDKDPSKFAQFVVENQEKTRRKVVDIGYERFLAPEIFFNPEIASSDFLTPLPTVVDQTIQACPIDVRKGLYNNIVLSGGSTMFKDFGRRLQRDLKSIVNNRIAQSELLSGTKSTGVDVSVISHRKQRNAVWFGGSLLAQTAEFKGYCHTKKDYEEYGPEIVR</Hsp_hseq>
      <Hsp_midline>A+V DNG+GL K GFAG+D+P  VFP              S VG P   S                             KRG                     +L YPI HG + NWD ME+ W +S +  LR  PE+H  LLTE PLNP  NRE++ +I FE+FN   +Y+A+QAVL+L AS  +        TG V+DSGDGVTH +P+ EGY +  AI  + +AGRD+T ++  +L ERG +  +  TAE+     IK++ CYV  D   E        S     + ++ E    +V+ IG ERF  PE  F P     +      T  + +I  C ID+RK LY N VLSGG+T+                                            + +VW GGS+LA  + F+    +K +Y+E GP IV </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YJL081C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:283802:285271:-1 gene:YJL081C transcript:YJL081C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ARP4 description:Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes [Source:SGD;Acc:S000003617]</Hit_def>
  <Hit_accession>YJL081C</Hit_accession>
  <Hit_len>489</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>96.2857</Hsp_bit-score>
      <Hsp_score>238</Hsp_score>
      <Hsp_evalue>1.03741e-22</Hsp_evalue>
      <Hsp_query-from>10</Hsp_query-from>
      <Hsp_query-to>741</Hsp_query-to>
      <Hsp_hit-from>12</Hsp_hit-from>
      <Hsp_hit-to>295</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>284</Hsp_align-len>
      <Hsp_qseq>EETTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGR-PRHQSKRGILT------------LKYPIEHGIITNWDDMEKIWHHSFYNELRIAPEEH-PTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKIL-----------TERGYSFVTTA--------------EREIVRDIKEKLCYVALDFENEMTMAASSSSLEKSYELPDGQVITIGNE-RFRCPETLFQP</Hsp_qseq>
      <Hsp_hseq>DEVSAVVIDPGSYTTNIGYSGSDFPQSILPSVYGKYTADEGNKKIFSEQSIGIPRKDYELKPIIENGLVIDWDTAQEQWQWALQNELYLNSNSGIPALLTEPVWNSTENRKKSLEVLLEGMQFEACYLAPTSTCVSFAAGRPNCLVVDIGHDTCSVSPIVDGMTLSKSTRRNFIAGKFINHLIKKALEPKEIIPLFAIKQRKPEFIKKTFDYEVDKSLYDYANNRGFFQECKETLCHICPTKTLEETKTELSSTAKRSIESPWNEEIVFDNETRYGFAEELFLP</Hsp_hseq>
      <Hsp_midline>+E +A+V D GS     G++G D P+++ PS+ G+    +  + I +            LK  IE+G++ +WD  ++ W  +  NEL +      P LLTE   N   NR+K  +++ E     A Y+A  +    +A+GR   +V+D G       PI +G  L  +  R  +AG+ +   + K L            +R   F+                  R   ++ KE LC++      E T    SS+ ++S E P  + I   NE R+   E LF P</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>3.35519e-11</Hsp_evalue>
      <Hsp_query-from>703</Hsp_query-from>
      <Hsp_query-to>957</Hsp_query-to>
      <Hsp_hit-from>363</Hsp_hit-from>
      <Hsp_hit-to>479</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>117</Hsp_align-len>
      <Hsp_qseq>NERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTI--------------------------------KYSVWIGGSILASLSTFQQMWISKPEYDEAG</Hsp_qseq>
      <Hsp_hseq>NETGKRPLEEEKPPKENNELIGLADLVYSSIMSSDVDLRATLAHNVVLTGGTSSIPGLSDRLMTELNKILPSLKFRILTTGHTIERQYQSWLGGSILTSLGTFHQLWVGKKEYEEVG</Hsp_hseq>
      <Hsp_midline>NE  + P    +P     E  G+ +  Y+SIM  D+D+R  L  N VL+GGT+                                 +Y  W+GGSIL SL TF Q+W+ K EY+E G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YNL059C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:512668:514935:-1 gene:YNL059C transcript:YNL059C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ARP5 description:Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes; promotes nucleosome shifts in the 3 prime direction [Source:SGD;Acc:S000005004]</Hit_def>
  <Hit_accession>YNL059C</Hit_accession>
  <Hit_len>755</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.5741</Hsp_bit-score>
      <Hsp_score>205</Hsp_score>
      <Hsp_evalue>3.80169e-18</Hsp_evalue>
      <Hsp_query-from>19</Hsp_query-from>
      <Hsp_query-to>660</Hsp_query-to>
      <Hsp_hit-from>38</Hsp_hit-from>
      <Hsp_hit-to>271</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>235</Hsp_align-len>
      <Hsp_qseq>TALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQSKRGILTL---------------KYPIEHGIITNWDDMEKIWHHSFYNELRIAPEE---HPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLY---ASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMTMAASSSSLE</Hsp_qseq>
      <Hsp_hseq>SPIAIDFGSSKLRAGFVNHATPTHIFPNALTKFRDRKLNKNFTFVGNDTLLDQAVRSQSRSPFDGPFVTNWNLTEEILDYTFHH-LGVVPDNGIPNPILLTERLATVQSQRTNWYQILFETYNVPGVTFGIDSLFSFYNYNPSGNKTGLVISCGHEDTNVIPVVDGAGILTDAKRINWGGHQAVDYLNDLMALKYPYFPTKMSYLQYETMYKDYCYVSRNYDEDIEKILTLENLD</Hsp_hseq>
      <Hsp_midline>+ +  D GS   +AGF     P  +FP+ + + R +      T                + P +   +TNW+  E+I  ++F++ L + P+    +P LLTE     ++ R    QI+FET+NVP +   I ++ S Y    SG  TG+V+  G   T+ +P+ +G  +     R++  G    DYL  ++  +   F T         + +  CYV+ +++ ++    +  +L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YPR034W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:639525:640958:1 gene:YPR034W transcript:YPR034W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ARP7 description:Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation [Source:SGD;Acc:S000006238]</Hit_def>
  <Hit_accession>YPR034W</Hit_accession>
  <Hit_len>477</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>3.43784e-13</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>513</Hsp_query-to>
      <Hsp_hit-from>8</Hsp_hit-from>
      <Hsp_hit-to>191</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>185</Hsp_align-len>
      <Hsp_qseq>LVCDNGSGLCKAGFAGDDAPRAVFPS--------------IVGR-----PRHQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRIAPEEHPTLLTEAPLNPKANR---EKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDY</Hsp_qseq>
      <Hsp_hseq>VVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAEKRNGDEVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAILERYYELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSKFGG-DFLDF</Hsp_hseq>
      <Hsp_midline>+V  NGS    AGF+  + P+ + PS              I G         + + G          G+  NWD +E  W + +  +L+++PEE P ++T    N K +    E+  ++ F+  NVP   + I+ +    + G+++  V+D G    +  PI +G  + +A++R    G D  D+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YLR085C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:300673:301989:-1 gene:YLR085C transcript:YLR085C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ARP6 description:Actin-related protein that binds nucleosomes; a component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A [Source:SGD;Acc:S000004075]</Hit_def>
  <Hit_accession>YLR085C</Hit_accession>
  <Hit_len>438</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>3.08158e-12</Hsp_evalue>
      <Hsp_query-from>13</Hsp_query-from>
      <Hsp_query-to>954</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>393</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>86</Hsp_identity>
      <Hsp_positive>147</Hsp_positive>
      <Hsp_gaps>84</Hsp_gaps>
      <Hsp_align-len>395</Hsp_align-len>
      <Hsp_qseq>ETTALVCDNGSGLCKAGFAGDDAPRAVFPSIV----------GRPRHQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRI------APEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYA----------SGRTTGI--------------------------------VLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEK--------------------LCYVALDFENEMTMAASSSSLEKSYELP-DGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGG--TTIKYSVWIGGSILASLSTFQQMWISKPEYDEA</Hsp_qseq>
      <Hsp_hseq>ETPPIVIDNGSYEIKFGPSTNKKPFRALNALAKDKFGTSYLSNHIKNIKDISSITFRRPHELGQLTLWELESCIWDYCLFNPSEFDGFDLKEGKGHHLVASESCMTLPELSKHADQVIFEEYEFDSLFKSPVAVFVPFTKSYKGEMRTISGKDEDIDIVRGNSDSTNSTSSESKNAQDSGSDYHDFQLVIDSGFNCTWIIPVLKGIPYYKAVKKLDIGGRFLTGLLKETLSFRHYNMMD--ETILVNNIKEQCLFVSPVSYFDSFKTKDKHALEYVLPDFQTSF-LGYVRNPRKENVPLPEDAQIITLTDELFTIPETFFHPEISQITKPGIVEAILESLSMLPEIVRPLMVGNIVCTGGNFNLPNFAQRLAAELQRQLPTDWTCHVSVPEGDCA</Hsp_hseq>
      <Hsp_midline>ET  +V DNGS   K G + +  P     ++              ++      +T + P E G +T W+    IW +  +N            + H  + +E+ +      +   Q++FE +   +++ +  AV   +           SG+   I                                V+DSG   T  +P+ +G     A+ +LD+ GR LT  L + L+ R Y+ +   E  +V +IKE+                    L YV  DF+    +    +  +++  LP D Q+IT+ +E F  PET F P    +   GI E    S+      +R  +  N V +GG      ++  +   +   L T     +S PE D A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>554496013</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055110-RA transcript Note:&quot;Protein of unknown function&quot; offset:285 AED:0.63 eAED:0.63 QI:285|0.5|0.57|0.57|0.5|0.42|7|0|290</Iteration_query-def>
  <Iteration_query-len>1158</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>682472765</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055111-RA transcript Note:&quot;Similar to Sipa1l2 Signal-induced proliferation-associated 1-like protein 2 (Mus musculus)&quot; offset:999 AED:0.00 eAED:0.00 QI:999|0.71|0.75|1|0.85|0.75|8|783|757</Iteration_query-def>
  <Iteration_query-len>4056</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>102</Statistics_hsp-len>
      <Statistics_eff-space>2801083750</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0028113-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.32 eAED:0.35 QI:0|0|0.4|1|0|0|5|2207|121</Iteration_query-def>
  <Iteration_query-len>2573</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1720855653</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055114-RA transcript Note:&quot;Similar to BOD1 Biorientation of chromosomes in cell division protein 1 (Homo sapiens)&quot; offset:306 AED:0.02 eAED:0.02 QI:306|1|1|1|1|1|3|942|192</Iteration_query-def>
  <Iteration_query-len>1827</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1175552438</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055098-RA transcript Note:&quot;Similar to s100a1 Protein S100-A1 (Misgurnus fossilis)&quot; offset:72 AED:0.01 eAED:0.01 QI:72|1|1|1|0.5|0.33|3|480|108</Iteration_query-def>
  <Iteration_query-len>879</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>89</Statistics_hsp-len>
      <Statistics_eff-space>474640068</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055099-RA transcript Note:&quot;Protein of unknown function&quot; offset:72 AED:0.01 eAED:0.01 QI:72|1|1|1|0.5|0.33|3|479|108</Iteration_query-def>
  <Iteration_query-len>878</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>89</Statistics_hsp-len>
      <Statistics_eff-space>472313401</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0035935-RA transcript Note:&quot;Similar to s100a1 Protein S100-A1 (Misgurnus fossilis)&quot; offset:0 AED:0.22 eAED:0.22 QI:0|0.6|0|1|0.6|0.5|6|346|219</Iteration_query-def>
  <Iteration_query-len>1006</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>568416415</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055101-RA transcript Note:&quot;Similar to s100a1 Protein S100-A1 (Misgurnus fossilis)&quot; offset:71 AED:0.02 eAED:0.02 QI:71|1|1|1|0.5|0.33|3|282|108</Iteration_query-def>
  <Iteration_query-len>680</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>86</Statistics_hsp-len>
      <Statistics_eff-space>328505380</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055104-RA transcript Note:&quot;Similar to APLF Aprataxin and PNK-like factor (Homo sapiens)&quot; offset:301 AED:0.26 eAED:0.26 QI:301|0.66|0.75|1|1|1|4|182|177</Iteration_query-def>
  <Iteration_query-len>1017</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>577696683</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0013487-RA transcript Note:&quot;Similar to ZNF615 Zinc finger protein 615 (Pongo abelii)&quot; offset:47 AED:0.75 eAED:0.91 QI:47|0|0|0.66|0|0|3|0|140</Iteration_query-def>
  <Iteration_query-len>470</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YOR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:534075:536819:1 gene:YOR113W transcript:YOR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AZF1 description:Zinc-finger transcription factor; involved in diauxic shift; in the presence of glucose, activates transcription of genes involved in growth and carbon metabolism; in nonfermentable carbon sources, activates transcription of genes involved in maintenance of cell wall integrity; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000005639]</Hit_def>
  <Hit_accession>YOR113W</Hit_accession>
  <Hit_len>914</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>1.13857e-13</Hsp_evalue>
      <Hsp_query-from>123</Hsp_query-from>
      <Hsp_query-to>356</Hsp_query-to>
      <Hsp_hit-from>598</Hsp_hit-from>
      <Hsp_hit-to>677</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>80</Hsp_align-len>
      <Hsp_qseq>CGKAFALTSKLKRHQMTH--SKPYFCNECGKRFSKLFNLKTHQVTHTGEWPHVCDACGKGFPHVSQLNTHKMTHTGEWPY</Hsp_qseq>
      <Hsp_hseq>CHRLFSQATHLEVHVRSHIGYKPFVCDYCGKRFTQGGNLRTHERLHTGEKPYSCDICDKKFSRKGNLAAHLVTHQKLKPF</Hsp_hseq>
      <Hsp_midline>C + F+  + L+ H  +H   KP+ C+ CGKRF++  NL+TH+  HTGE P+ CD C K F     L  H +TH    P+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>2.0555e-09</Hsp_evalue>
      <Hsp_query-from>180</Hsp_query-from>
      <Hsp_query-to>359</Hsp_query-to>
      <Hsp_hit-from>591</Hsp_hit-from>
      <Hsp_hit-to>650</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>26</Hsp_identity>
      <Hsp_positive>34</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>60</Hsp_align-len>
      <Hsp_qseq>KPYFCNECGKRFSKLFNLKTHQVTHTGEWPHVCDACGKGFPHVSQLNTHKMTHTGEWPYN</Hsp_qseq>
      <Hsp_hseq>KKHECPYCHRLFSQATHLEVHVRSHIGYKPFVCDYCGKRFTQGGNLRTHERLHTGEKPYS</Hsp_hseq>
      <Hsp_midline>K + C  C + FS+  +L+ H  +H G  P VCD CGK F     L TH+  HTGE PY+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>3.10169e-09</Hsp_evalue>
      <Hsp_query-from>123</Hsp_query-from>
      <Hsp_query-to>329</Hsp_query-to>
      <Hsp_hit-from>626</Hsp_hit-from>
      <Hsp_hit-to>698</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>38</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>73</Hsp_align-len>
      <Hsp_qseq>CGKAFALTSKLKRHQMTHS--KPYFCNECGKRFSKLFNLKTHQVTHTGEWPHVC--DACGKGFPHVSQLNTHK</Hsp_qseq>
      <Hsp_hseq>CGKRFTQGGNLRTHERLHTGEKPYSCDICDKKFSRKGNLAAHLVTHQKLKPFVCKLENCNKTFTQLGNMKAHQ</Hsp_hseq>
      <Hsp_midline>CGK F     L+ H+  H+  KPY C+ C K+FS+  NL  H VTH    P VC  + C K F  +  +  H+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YJL056C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:330431:333073:-1 gene:YJL056C transcript:YJL056C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZAP1 description:Zinc-regulated transcription factor; binds to zinc-responsive promoters to induce transcription of certain genes in presence of zinc, represses other genes in low zinc; regulates its own transcription; contains seven zinc-finger domains [Source:SGD;Acc:S000003592]</Hit_def>
  <Hit_accession>YJL056C</Hit_accession>
  <Hit_len>880</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>1.22369e-11</Hsp_evalue>
      <Hsp_query-from>120</Hsp_query-from>
      <Hsp_query-to>365</Hsp_query-to>
      <Hsp_hit-from>744</Hsp_hit-from>
      <Hsp_hit-to>827</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>41</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>ECGKAFALTSKLKRHQMTHSK--PYFCNECGKRFSKLFNLKTHQVTHTGEWPHVCDACGKGFPHVSQLNTHKMTHTGEWPYNFK</Hsp_qseq>
      <Hsp_hseq>DCHRTFPQRQKLIRHLKVHSKYKPYKCKTCKRCFSSEETLVQHTRTHSGEKPYKCHICNKKFAISSSLKIHIRTHTGEKPLQCK</Hsp_hseq>
      <Hsp_midline>+C + F    KL RH   HSK  PY C  C + FS    L  H  TH+GE P+ C  C K F   S L  H  THTGE P   K</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>4.92183e-11</Hsp_evalue>
      <Hsp_query-from>123</Hsp_query-from>
      <Hsp_query-to>350</Hsp_query-to>
      <Hsp_hit-from>773</Hsp_hit-from>
      <Hsp_hit-to>850</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>43</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>78</Hsp_align-len>
      <Hsp_qseq>CGKAFALTSKLKRHQMTHS--KPYFCNECGKRFSKLFNLKTHQVTHTGEWPHVCDACGKGFPHVSQLNTHKMTHTGEW</Hsp_qseq>
      <Hsp_hseq>CKRCFSSEETLVQHTRTHSGEKPYKCHICNKKFAISSSLKIHIRTHTGEKPLQCKICGKRFNESSNLSKHIKTHQKKY</Hsp_hseq>
      <Hsp_midline>C + F+    L +H  THS  KPY C+ C K+F+   +LK H  THTGE P  C  CGK F   S L+ H  TH  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YNL027W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:579580:581616:1 gene:YNL027W transcript:YNL027W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CRZ1 description:Transcription factor, activates transcription of stress response genes; nuclear localization is positively regulated by calcineurin-mediated dephosphorylation; rapidly localizes to the nucleus under blue light stress; can be activated in stochastic pulses of nuclear localization in response to calcium [Source:SGD;Acc:S000004972]</Hit_def>
  <Hit_accession>YNL027W</Hit_accession>
  <Hit_len>678</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>3.63222e-11</Hsp_evalue>
      <Hsp_query-from>186</Hsp_query-from>
      <Hsp_query-to>356</Hsp_query-to>
      <Hsp_hit-from>569</Hsp_hit-from>
      <Hsp_hit-to>625</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>34</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>57</Hsp_align-len>
      <Hsp_qseq>YFCNECGKRFSKLFNLKTHQVTHTGEWPHVCDACGKGFPHVSQLNTHKMTHTGEWPY</Hsp_qseq>
      <Hsp_hseq>FACDVCGKKFTRPYNLKSHLRTHTNERPFICSICGKAFARQHDRKRHEDLHTGKKRY</Hsp_hseq>
      <Hsp_midline>+ C+ CGK+F++ +NLK+H  THT E P +C  CGK F        H+  HTG+  Y</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>4.4386e-10</Hsp_evalue>
      <Hsp_query-from>123</Hsp_query-from>
      <Hsp_query-to>344</Hsp_query-to>
      <Hsp_hit-from>574</Hsp_hit-from>
      <Hsp_hit-to>658</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>41</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>85</Hsp_align-len>
      <Hsp_qseq>CGKAFALTSKLKRHQMTHS--KPYFCNECGKRFSKLFNLKTHQVTHTGEWPHVCD---------ACGKGFPHVSQLNTHKMTHTG</Hsp_qseq>
      <Hsp_hseq>CGKKFTRPYNLKSHLRTHTNERPFICSICGKAFARQHDRKRHEDLHTGKKRYVCGGKLKDGKPWGCGKKFARSDALGRHFKTESG</Hsp_hseq>
      <Hsp_midline>CGK F     LK H  TH+  +P+ C+ CGK F++  + K H+  HTG+  +VC           CGK F     L  H  T +G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YGL209W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:95858:97006:1 gene:YGL209W transcript:YGL209W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MIG2 description:Zinc finger transcriptional repressor; cooperates with Mig1p in glucose-induced gene repression; under low glucose conditions relocalizes to mitochondrion, where it interacts with Ups1p, antagonizes mitochondrial fission factor Dnm1p, indicative of a role in mitochondrial fusion or regulating morphology; regulates filamentous growth in response to glucose depletion; activated in stochastic pulses of nuclear localization in response to low glucose [Source:SGD;Acc:S000003177]</Hit_def>
  <Hit_accession>YGL209W</Hit_accession>
  <Hit_len>382</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>3.92891e-09</Hsp_evalue>
      <Hsp_query-from>177</Hsp_query-from>
      <Hsp_query-to>377</Hsp_query-to>
      <Hsp_hit-from>14</Hsp_hit-from>
      <Hsp_hit-to>82</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>37</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>69</Hsp_align-len>
      <Hsp_qseq>SKPYFCNECGKRFSKLFNLKTHQVTHTGEWPHVC--DACGKGFPHVSQLNTHKMTHTGEWPYNFKAAIV</Hsp_qseq>
      <Hsp_hseq>NRPFRCDTCHRGFHRLEHKKRHLRTHTGEKPHHCAFPGCGKSFSRSDELKRHMRTHTGQSQRRLKKASV</Hsp_hseq>
      <Hsp_midline>++P+ C+ C + F +L + K H  THTGE PH C    CGK F    +L  H  THTG+     K A V</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YPR186C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:909733:911022:-1 gene:YPR186C transcript:YPR186C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PZF1 description:Transcription factor IIIA (TFIIIA); essential DNA binding protein required for transcription of 5S rRNA by RNA polymerase III; not involved in transcription of other RNAP III genes; nine conserved zinc fingers; may also bind 5S rRNA [Source:SGD;Acc:S000006390]</Hit_def>
  <Hit_accession>YPR186C</Hit_accession>
  <Hit_len>429</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>9.528e-09</Hsp_evalue>
      <Hsp_query-from>93</Hsp_query-from>
      <Hsp_query-to>350</Hsp_query-to>
      <Hsp_hit-from>46</Hsp_hit-from>
      <Hsp_hit-to>134</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>44</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>89</Hsp_align-len>
      <Hsp_qseq>PPALTAAHQECGKAFALTSKLKRHQMT-HS--KPYFCNECGKRFSKLFNLKTHQVTHTGEWPHVCDACGKGFPHVSQLNTHKMTHTGEW</Hsp_qseq>
      <Hsp_hseq>PKTYFCDYDGCDKAFTRPSILTEHQLSVHQGLRAFQCDKCAKSFVKKSHLERHLYTHSDTKPFQCSYCGKGVTTRQQLKRHEVTHTKSF</Hsp_hseq>
      <Hsp_midline>P      +  C KAF   S L  HQ++ H   + + C++C K F K  +L+ H  TH+   P  C  CGKG     QL  H++THT  +</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>44.2838</Hsp_bit-score>
      <Hsp_score>103</Hsp_score>
      <Hsp_evalue>1.86284e-06</Hsp_evalue>
      <Hsp_query-from>123</Hsp_query-from>
      <Hsp_query-to>335</Hsp_query-to>
      <Hsp_hit-from>85</Hsp_hit-from>
      <Hsp_hit-to>157</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>38</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>73</Hsp_align-len>
      <Hsp_qseq>CGKAFALTSKLKRHQMTHS--KPYFCNECGKRFSKLFNLKTHQVTHTGEWPHVCDACGKGFPHVSQLNTHKMT</Hsp_qseq>
      <Hsp_hseq>CAKSFVKKSHLERHLYTHSDTKPFQCSYCGKGVTTRQQLKRHEVTHTKSFICPEEGCNLRFYKHPQLRAHILS</Hsp_hseq>
      <Hsp_midline>C K+F   S L+RH  THS  KP+ C+ CGK  +    LK H+VTHT  +    + C   F    QL  H ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YGL254W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:22304:23203:1 gene:YGL254W transcript:YGL254W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FZF1 description:Transcription factor involved in sulfite metabolism; sole identified regulatory target is SSU1; overexpression suppresses sulfite-sensitivity of many unrelated mutants due to hyperactivation of SSU1, contains five zinc fingers; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003223]</Hit_def>
  <Hit_accession>YGL254W</Hit_accession>
  <Hit_len>299</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>3.44811e-08</Hsp_evalue>
      <Hsp_query-from>123</Hsp_query-from>
      <Hsp_query-to>338</Hsp_query-to>
      <Hsp_hit-from>19</Hsp_hit-from>
      <Hsp_hit-to>94</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>42</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>76</Hsp_align-len>
      <Hsp_qseq>CGKAFALTSKLKRHQMTHS--KPYFCNE--CGKRFSKLFNLKTHQVTHTGEWPHVCDACGKGFPHVSQLNTHKMTH</Hsp_qseq>
      <Hsp_hseq>CEKVYNRPSLLQQHQNSHTNQKPYHCDEPGCGKKFIRPCHLRVHKWTHSQIKPKACTLCQKRFVTNQQLRRHLNSH</Hsp_hseq>
      <Hsp_midline>C K +   S L++HQ +H+  KPY C+E  CGK+F +  +L+ H+ TH+   P  C  C K F    QL  H  +H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YPL038W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:480535:481068:1 gene:YPL038W transcript:YPL038W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MET31 description:Zinc-finger DNA-binding transcription factor; targets strong transcriptional activator Met4p to promoters of sulfur metabolic genes; involved in transcriptional regulation of the methionine biosynthetic genes; feedforward loop controlling expression of MET32 and the lack of such a loop for MET31 may account for the differential actions of Met31p and Met32p; MET31 has a paralog, MET32, that arose from the whole genome duplication [Source:SGD;Acc:S000005959]</Hit_def>
  <Hit_accession>YPL038W</Hit_accession>
  <Hit_len>177</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.9802</Hsp_bit-score>
      <Hsp_score>110</Hsp_score>
      <Hsp_evalue>1.23276e-07</Hsp_evalue>
      <Hsp_query-from>162</Hsp_query-from>
      <Hsp_query-to>341</Hsp_query-to>
      <Hsp_hit-from>87</Hsp_hit-from>
      <Hsp_hit-to>146</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>31</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>60</Hsp_align-len>
      <Hsp_qseq>HQMTHSKPYFCNECGKRFSKLFNLKTHQVTHTGEWPHVCDACGKGFPHVSQLNTHKMTHT</Hsp_qseq>
      <Hsp_hseq>HSKEGAQLYSCAKCQLKFSRSSDLRRHEKVHSLVLPHICSNCGKGFARKDALKRHSNTLT</Hsp_hseq>
      <Hsp_midline>H    ++ Y C +C  +FS+  +L+ H+  H+   PH+C  CGKGF     L  H  T T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YDR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:637139:639823:1 gene:YDR096W transcript:YDR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIS1 description:Histone demethylase and transcription factor; regulates genes during nutrient limitation; activity modulated by proteasome-mediated proteolysis; has JmjC and JmjN domain in N-terminus that interact, promoting stability and proper transcriptional activity; contains two transactivating domains downstream of Jmj domains and a C-terminal DNA binding domain; relocalizes to the cytosol in response to hypoxia; GIS1 has a paralog, RPH1, that arose from the whole genome duplication [Source:SGD;Acc:S000002503]</Hit_def>
  <Hit_accession>YDR096W</Hit_accession>
  <Hit_len>894</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.4394</Hsp_bit-score>
      <Hsp_score>106</Hsp_score>
      <Hsp_evalue>8.61231e-07</Hsp_evalue>
      <Hsp_query-from>174</Hsp_query-from>
      <Hsp_query-to>347</Hsp_query-to>
      <Hsp_hit-from>824</Hsp_hit-from>
      <Hsp_hit-to>885</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>26</Hsp_identity>
      <Hsp_positive>33</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>62</Hsp_align-len>
      <Hsp_qseq>HSKPYFCNECGKRFSKLFNLKTHQVT-HTGEWPHVCDACGKGFP---HVSQLNTHKMTHTGE</Hsp_qseq>
      <Hsp_hseq>HGKIYICRECNRQFSSGHHLTRHKKSVHSGEKPHSCPRCGKRFKRRDHVLQHLNKKIPCTQE</Hsp_hseq>
      <Hsp_midline>H K Y C EC ++FS   +L  H+ + H+GE PH C  CGK F    HV Q    K+  T E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YDR253C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:963990:964565:-1 gene:YDR253C transcript:YDR253C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MET32 description:Zinc-finger DNA-binding transcription factor; involved in transcriptional regulation of the methionine biosynthetic genes; targets strong transcriptional activator Met4p to promoters of sulfur metabolic genes; feedforward loop exists in the regulation of genes controlled by Met4p and Met32p; lack of such a loop for MET31 may account for the differential actions of Met32p and Met31p; MET32 has a paralog, MET31, that arose from the whole genome duplication [Source:SGD;Acc:S000002661]</Hit_def>
  <Hit_accession>YDR253C</Hit_accession>
  <Hit_len>191</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>44.669</Hsp_bit-score>
      <Hsp_score>104</Hsp_score>
      <Hsp_evalue>9.88257e-07</Hsp_evalue>
      <Hsp_query-from>159</Hsp_query-from>
      <Hsp_query-to>341</Hsp_query-to>
      <Hsp_hit-from>89</Hsp_hit-from>
      <Hsp_hit-to>149</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>22</Hsp_identity>
      <Hsp_positive>30</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>61</Hsp_align-len>
      <Hsp_qseq>RHQMTHSKPYFCNECGKRFSKLFNLKTHQVTHTGEWPHVCDACGKGFPHVSQLNTHKMTHT</Hsp_qseq>
      <Hsp_hseq>RRNSTGEKRFKCAKCSLEFSRSSDLRRHEKTHFAILPNICPQCGKGFARKDALKRHYDTLT</Hsp_hseq>
      <Hsp_midline>R   T  K + C +C   FS+  +L+ H+ TH    P++C  CGKGF     L  H  T T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YML081W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:104777:108532:1 gene:YML081W transcript:YML081W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TDA9 description:Transcription factor that regulates acetate production; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; TDA9 has a paralog, RSF2, that arose from the whole genome duplication [Source:SGD;Acc:S000004546]</Hit_def>
  <Hit_accession>YML081W</Hit_accession>
  <Hit_len>1251</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>44.669</Hsp_bit-score>
      <Hsp_score>104</Hsp_score>
      <Hsp_evalue>1.67754e-06</Hsp_evalue>
      <Hsp_query-from>90</Hsp_query-from>
      <Hsp_query-to>299</Hsp_query-to>
      <Hsp_hit-from>29</Hsp_hit-from>
      <Hsp_hit-to>98</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>20</Hsp_identity>
      <Hsp_positive>35</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>70</Hsp_align-len>
      <Hsp_qseq>SPPALTAAHQECGKAFALTSKLKRHQMTHSKPYFCNECGKRFSKLFNLKTHQVTHTGEWPHVCDACGKGF</Hsp_qseq>
      <Hsp_hseq>APPCVGATGNDKIQVLPIPKKSRTIKTDKPRPFLCHICTRGFVRQEHLKRHQRAHTNEKPFLCVFCGRCF</Hsp_hseq>
      <Hsp_midline>+PP + A   +  +   +  K +  +    +P+ C+ C + F +  +LK HQ  HT E P +C  CG+ F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YER028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:210692:211876:-1 gene:YER028C transcript:YER028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MIG3 description:Transcriptional regulator; partially nonfunctional in S288C strains but has a major role in catabolite repression and ethanol response in some other strains; involved in response to toxic agents; phosphorylation by Snf1p or the Mec1p pathway inactivates Mig3p, allowing induction of damage response genesenvironment [Source:SGD;Acc:S000000830]</Hit_def>
  <Hit_accession>YER028C</Hit_accession>
  <Hit_len>394</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>43.8986</Hsp_bit-score>
      <Hsp_score>102</Hsp_score>
      <Hsp_evalue>2.82133e-06</Hsp_evalue>
      <Hsp_query-from>180</Hsp_query-from>
      <Hsp_query-to>341</Hsp_query-to>
      <Hsp_hit-from>15</Hsp_hit-from>
      <Hsp_hit-to>70</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>29</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>56</Hsp_align-len>
      <Hsp_qseq>KPYFCNECGKRFSKLFNLKTHQVTHTGEWPHVC--DACGKGFPHVSQLNTHKMTHT</Hsp_qseq>
      <Hsp_hseq>RPFRCEICSRGFHRLEHKKRHGRTHTGEKPHKCTVQGCPKSFSRSDELKRHLRTHT</Hsp_hseq>
      <Hsp_midline>+P+ C  C + F +L + K H  THTGE PH C    C K F    +L  H  THT</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YGL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:431548:433062:-1 gene:YGL035C transcript:YGL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MIG1 description:Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase; regulates filamentous growth along with Mig2p in response to glucose depletion; activated in stochastic pulses of nuclear localization, shuttling between cytosol and nucleus depending on external glucose levels and its phosphorylation state [Source:SGD;Acc:S000003003]</Hit_def>
  <Hit_accession>YGL035C</Hit_accession>
  <Hit_len>504</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>43.8986</Hsp_bit-score>
      <Hsp_score>102</Hsp_score>
      <Hsp_evalue>3.22751e-06</Hsp_evalue>
      <Hsp_query-from>180</Hsp_query-from>
      <Hsp_query-to>353</Hsp_query-to>
      <Hsp_hit-from>36</Hsp_hit-from>
      <Hsp_hit-to>95</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>22</Hsp_identity>
      <Hsp_positive>29</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>60</Hsp_align-len>
      <Hsp_qseq>KPYFCNECGKRFSKLFNLKTHQVTHTGEWPHVCD--ACGKGFPHVSQLNTHKMTHTGEWP</Hsp_qseq>
      <Hsp_hseq>RPHACPICHRAFHRLEHQTRHMRIHTGEKPHACDFPGCVKRFSRSDELTRHRRIHTNSHP</Hsp_hseq>
      <Hsp_midline>+P+ C  C + F +L +   H   HTGE PH CD   C K F    +L  H+  HT   P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>82</Statistics_hsp-len>
      <Statistics_eff-space>175592158</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055108-RA transcript Note:&quot;Similar to Moxd1 DBH-like monooxygenase protein 1 (Mus musculus)&quot; offset:0 AED:0.39 eAED:0.39 QI:0|0|0|0.25|1|1|12|0|567</Iteration_query-def>
  <Iteration_query-len>1704</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1081782691</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055109-RA transcript Note:&quot;Similar to NOVA1 RNA-binding protein Nova-1 (Macaca fascicularis)&quot; offset:0 AED:0.10 eAED:0.10 QI:0|0|0|0.66|1|1|3|0|444</Iteration_query-def>
  <Iteration_query-len>1335</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YBL032W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:160184:161329:1 gene:YBL032W transcript:YBL032W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HEK2 description:RNA binding protein involved in asymmetric localization of ASH1 mRNA; represses translation of ASH1 mRNA, an effect reversed by Yck1p-dependent phosphoryation; regulates telomere position effect and length; similarity to hnRNP-K [Source:SGD;Acc:S000000128]</Hit_def>
  <Hit_accession>YBL032W</Hit_accession>
  <Hit_len>381</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>2.07569e-06</Hsp_evalue>
      <Hsp_query-from>37</Hsp_query-from>
      <Hsp_query-to>258</Hsp_query-to>
      <Hsp_hit-from>154</Hsp_hit-from>
      <Hsp_hit-to>225</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>42</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>74</Hsp_align-len>
      <Hsp_qseq>EGLYFLKILIPSYAAGSIIGKGGQTIVQLQKDSGATIKLSKSKDFYPGTTERVALIQGAPDSLNGVHCFIADKI</Hsp_qseq>
      <Hsp_hseq>EDIGYVRLIVANSHISSIIGKAGATIKSLINKHG--VKIVASKDFLPASDERIIEIQGFPGSITNVLIEISEII</Hsp_hseq>
      <Hsp_midline>E + ++++++ +    SIIGK G TI  L    G  +K+  SKDF P + ER+  IQG P S+  V   I++ I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>93</Statistics_hsp-len>
      <Statistics_eff-space>809693984</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0034355-RA transcript Note:&quot;Similar to Cdkl4 Cyclin-dependent kinase-like 4 (Mus musculus)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0|0|2|735|87</Iteration_query-def>
  <Iteration_query-len>999</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>563776281</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055112-RA transcript Note:&quot;Similar to cdkl1 Cyclin-dependent kinase-like 1 (Danio rerio)&quot; offset:0 AED:0.21 eAED:0.22 QI:0|0|0|1|1|1|2|0|105</Iteration_query-def>
  <Iteration_query-len>318</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>111.694</Hsp_bit-score>
      <Hsp_score>278</Hsp_score>
      <Hsp_evalue>3.95366e-31</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>294</Hsp_query-to>
      <Hsp_hit-from>141</Hsp_hit-from>
      <Hsp_hit-to>234</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>97</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLITKTLG</Hsp_qseq>
      <Hsp_hseq>IHRDLKPSNILINENCDLKICDFGLARI---QDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLG</Hsp_hseq>
      <Hsp_midline>IHRD+KP NILI ++  +K+CDFG AR+   Q+ + T YV+TR+YRAPE+++   +Y   VD+W+AGC+FAEM+ G  L+PG   +HQ  +IT  LG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>110.153</Hsp_bit-score>
      <Hsp_score>274</Hsp_score>
      <Hsp_evalue>7.53426e-31</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>294</Hsp_query-to>
      <Hsp_hit-from>140</Hsp_hit-from>
      <Hsp_hit-to>243</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>104</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDR-------YTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLITKTLG</Hsp_qseq>
      <Hsp_hseq>IHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLG</Hsp_hseq>
      <Hsp_midline>IHRD+KP N+L+  +  +K+CDFG AR L    D         T+YVATRWYRAPE+++   +Y  A+D+W+ GC+ AEM+ G  L+PG    HQL LI + LG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>109.383</Hsp_bit-score>
      <Hsp_score>272</Hsp_score>
      <Hsp_evalue>9.60779e-30</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>294</Hsp_query-to>
      <Hsp_hit-from>192</Hsp_hit-from>
      <Hsp_hit-to>300</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>109</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLL------------TGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLITKTLG</Hsp_qseq>
      <Hsp_hseq>MHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLG</Hsp_hseq>
      <Hsp_midline>+HRD+K  NILI  +GV+KL DFG ARL              G   +YT  V TRWYRAPEL++GD QY  AVD+W  GCVFAE      +  G +D+ Q H+I K LG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>107.071</Hsp_bit-score>
      <Hsp_score>266</Hsp_score>
      <Hsp_evalue>1.03555e-29</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>294</Hsp_query-to>
      <Hsp_hit-from>134</Hsp_hit-from>
      <Hsp_hit-to>240</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>107</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLL----------TGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLITKTLG</Hsp_qseq>
      <Hsp_hseq>IHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIG</Hsp_hseq>
      <Hsp_midline>IHRD+KP N+LI  +  +K+CDFG AR++          TGQ+   T+YVATRWYRAPE+++   +Y  A+DVW+ GC+ AE+     ++PG    HQL LI   +G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>103.219</Hsp_bit-score>
      <Hsp_score>256</Hsp_score>
      <Hsp_evalue>1.12548e-28</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>294</Hsp_query-to>
      <Hsp_hit-from>129</Hsp_hit-from>
      <Hsp_hit-to>226</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>98</Hsp_align-len>
      <Hsp_qseq>CIHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLITKTLG</Hsp_qseq>
      <Hsp_hseq>ILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMG</Hsp_hseq>
      <Hsp_midline> +HRD+KP+N+LI K G +KL DFG AR      + ++  V T WYRAP++L+G   Y  ++D+W+ GC+ AEM+ G  L+PG +D  QL LI   +G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>103.99</Hsp_bit-score>
      <Hsp_score>258</Hsp_score>
      <Hsp_evalue>2.38283e-28</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>294</Hsp_query-to>
      <Hsp_hit-from>163</Hsp_hit-from>
      <Hsp_hit-to>267</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>105</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLL--------TGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLITKTLG</Hsp_qseq>
      <Hsp_hseq>IHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLG</Hsp_hseq>
      <Hsp_midline>IHRD+KP NIL T +G +K+CDFG AR +        +  +   T+YVATRWYRAPELL+ +  Y  +VD+WA GC+ AE      ++ G   +HQ+  I K LG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>97.8265</Hsp_bit-score>
      <Hsp_score>242</Hsp_score>
      <Hsp_evalue>1.20593e-26</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>294</Hsp_query-to>
      <Hsp_hit-from>132</Hsp_hit-from>
      <Hsp_hit-to>229</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>98</Hsp_align-len>
      <Hsp_qseq>CIHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLITKTLG</Hsp_qseq>
      <Hsp_hseq>ILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLG</Hsp_hseq>
      <Hsp_midline> +HRD+KP+N+LI K G +KL DFG AR        YT  + T WYRAPE+L+G  QY   VD W+ GC+FAEM     ++ G+S++ Q+  I + LG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>98.9821</Hsp_bit-score>
      <Hsp_score>245</Hsp_score>
      <Hsp_evalue>1.30731e-26</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>294</Hsp_query-to>
      <Hsp_hit-from>162</Hsp_hit-from>
      <Hsp_hit-to>257</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>97</Hsp_align-len>
      <Hsp_qseq>HRDVKPENILIT-KHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLITKTLG</Hsp_qseq>
      <Hsp_hseq>HRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSIS-YICSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLREIAKLLG</Hsp_hseq>
      <Hsp_midline>HRD+KP N+L+  + GV+K+CDFG A+ L   +   + Y+ +R+YRAPEL++G TQY   +D+W  GCV  EML G A++ G   L QL  I K LG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>97.4413</Hsp_bit-score>
      <Hsp_score>241</Hsp_score>
      <Hsp_evalue>1.70622e-26</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>309</Hsp_query-to>
      <Hsp_hit-from>125</Hsp_hit-from>
      <Hsp_hit-to>227</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>103</Hsp_align-len>
      <Hsp_qseq>CIHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLITKTLGDLRSR</Hsp_qseq>
      <Hsp_hseq>ILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDR</Hsp_hseq>
      <Hsp_midline> +HRD+KP N+L +  G +K+ DFG AR +    +  T  V TRWYRAPELL G   Y  A+D+W+ G +FAE++      PG +D+ Q+ +  + LG    R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>98.5969</Hsp_bit-score>
      <Hsp_score>244</Hsp_score>
      <Hsp_evalue>4.6266e-26</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>294</Hsp_query-to>
      <Hsp_hit-from>303</Hsp_hit-from>
      <Hsp_hit-to>398</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>97</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLITKTLG</Hsp_qseq>
      <Hsp_hseq>LHRDVKGSNILIDNQGNLKITDFGLARKMNSRAD-YTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMG</Hsp_hseq>
      <Hsp_midline>+HRDVK  NILI   G +K+ DFG AR +  + D YT+ V T WYR PELL+G T YG  VD+W  GC+  E+    A++ G+++L Q+  I K +G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>97.0561</Hsp_bit-score>
      <Hsp_score>240</Hsp_score>
      <Hsp_evalue>5.75514e-26</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>294</Hsp_query-to>
      <Hsp_hit-from>162</Hsp_hit-from>
      <Hsp_hit-to>257</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>97</Hsp_align-len>
      <Hsp_qseq>HRDVKPENILITKHG-VVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLITKTLG</Hsp_qseq>
      <Hsp_hseq>HRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVS-YICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILG</Hsp_hseq>
      <Hsp_midline>HRD+KP+N+L+      +KLCDFG A+ L   E   + Y+ +R+YRAPEL+ G T Y   +D+W++GCV AE+L G  ++PG S + QL  I K LG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>96.2857</Hsp_bit-score>
      <Hsp_score>238</Hsp_score>
      <Hsp_evalue>3.01658e-25</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>294</Hsp_query-to>
      <Hsp_hit-from>150</Hsp_hit-from>
      <Hsp_hit-to>250</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>101</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQ----EDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLITKTLG</Hsp_qseq>
      <Hsp_hseq>LHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLG</Hsp_hseq>
      <Hsp_midline>+HRD+KP N+L+     +K+CDFG AR  +          T+YVATRWYRAPE+++    Y  A+DVW+AGC+ AE L G  ++ G   ++QL+ I + LG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YDL079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:312951:314748:-1 gene:YDL079C transcript:YDL079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRK1 description:Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication [Source:SGD;Acc:S000002237]</Hit_def>
  <Hit_accession>YDL079C</Hit_accession>
  <Hit_len>501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.5077</Hsp_bit-score>
      <Hsp_score>223</Hsp_score>
      <Hsp_evalue>3.68541e-23</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>294</Hsp_query-to>
      <Hsp_hit-from>287</Hsp_hit-from>
      <Hsp_hit-to>382</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>97</Hsp_align-len>
      <Hsp_qseq>HRDVKPENILITKHGV-VKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLITKTLG</Hsp_qseq>
      <Hsp_hseq>HRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVS-YICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKIMG</Hsp_hseq>
      <Hsp_midline>HRD+KP+N+L+       K+CDFG A+ L   +   + Y+ +R+YRAPEL+ G T Y   VDVW++ CV AE+L G  L+ G S + QL  I K +G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.1225</Hsp_bit-score>
      <Hsp_score>222</Hsp_score>
      <Hsp_evalue>4.86502e-23</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>294</Hsp_query-to>
      <Hsp_hit-from>191</Hsp_hit-from>
      <Hsp_hit-to>302</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>113</Hsp_align-len>
      <Hsp_qseq>HRDVKPENILIT-----------------KHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLITKTLG</Hsp_qseq>
      <Hsp_hseq>HRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVENK-NPYTAYVSTRWYRSPEILLRSGYYSKPLDIWAFGCVAVEVTVFRALFPGANEIDQIWKILEVLG</Hsp_hseq>
      <Hsp_midline>HRD+KPENILIT                  + V+KL DFG AR +  + + YT YV+TRWYR+PE+L+    Y   +D+WA GCV  E+    AL+PG +++ Q+  I + LG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.8853</Hsp_bit-score>
      <Hsp_score>211</Hsp_score>
      <Hsp_evalue>9.12183e-22</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>294</Hsp_query-to>
      <Hsp_hit-from>171</Hsp_hit-from>
      <Hsp_hit-to>266</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>97</Hsp_align-len>
      <Hsp_qseq>HRDVKPENILIT-KHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLITKTLG</Hsp_qseq>
      <Hsp_hseq>HGDLKPSNILIIPSSGIAKVCDFGSAQRLDDNTELKT-YFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPLFKGDSANSQLEEIAKLLG</Hsp_hseq>
      <Hsp_midline>H D+KP NILI    G+ K+CDFG A+ L    +  T Y  +R+YRAPELL+    Y   +D+W+ GC+  EM+ G  L+ G+S   QL  I K LG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>84.7297</Hsp_bit-score>
      <Hsp_score>208</Hsp_score>
      <Hsp_evalue>3.73546e-21</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>294</Hsp_query-to>
      <Hsp_hit-from>283</Hsp_hit-from>
      <Hsp_hit-to>393</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>111</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQ-EDRYT--DYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNS-----------DLHQLHLITKTLG</Hsp_qseq>
      <Hsp_hseq>LHRDLKPANIMVTIDGCVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELIGLQPIFKGEEAKLDSKKTVPFQVNQLQRILEVLG</Hsp_hseq>
      <Hsp_midline>+HRD+KP NI++T  G VK+ D G AR      +  YT    V T WYRAPELL+G   Y PAVD+W+ GC+FAE++    ++ G              ++QL  I + LG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.3294</Hsp_bit-score>
      <Hsp_score>181</Hsp_score>
      <Hsp_evalue>1.52448e-17</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>294</Hsp_query-to>
      <Hsp_hit-from>493</Hsp_hit-from>
      <Hsp_hit-to>587</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>101</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILIT--KHGVVKLCDFGFARLLTGQEDR--YTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLITKTLG</Hsp_qseq>
      <Hsp_hseq>IHCDLKPENILLCAPDKPELKIIDFGS----SCEEARTVYT-YIQSRFYRAPEIILG-IPYSTSIDMWSLGCIVAELFLGIPIFPGASEYNQLTRIIDTLG</Hsp_hseq>
      <Hsp_midline>IH D+KPENIL+       +K+ DFG     + +E R  YT Y+ +R+YRAPE+++G   Y  ++D+W+ GC+ AE+  G  ++PG S+ +QL  I  TLG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.7886</Hsp_bit-score>
      <Hsp_score>177</Hsp_score>
      <Hsp_evalue>6.75827e-17</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>231</Hsp_query-to>
      <Hsp_hit-from>535</Hsp_hit-from>
      <Hsp_hit-to>608</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>76</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCG</Hsp_qseq>
      <Hsp_hseq>VYRDLKPENILLDANGNIALCDFGLSK--ADLKDRTNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCG</Hsp_hseq>
      <Hsp_midline>++RD+KPENIL+  +G + LCDFG ++     +DR   +  T  Y APELL+ +T Y   VD W+ G +  EM CG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>2.14629e-16</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>279</Hsp_query-to>
      <Hsp_hit-from>736</Hsp_hit-from>
      <Hsp_hit-to>826</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>92</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLI</Hsp_qseq>
      <Hsp_hseq>LHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTMVGTPYWMAPE-VVSRKEYGPKVDIWSLGIMIIEMIEGEPPYLNETPLRALYLI</Hsp_hseq>
      <Hsp_midline>+HRD+K +NIL++  G +KL DFGF   +     + T  V T ++ APE +V   +YGP VD+W+ G +  EM+ G   +   + L  L+LI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>7.65108e-16</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>231</Hsp_query-to>
      <Hsp_hit-from>467</Hsp_hit-from>
      <Hsp_hit-to>541</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>76</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCG</Hsp_qseq>
      <Hsp_hseq>VYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLG-LGYTKAVDWWTLGVLLYEMLTG</Hsp_hseq>
      <Hsp_midline>++RD+KPENIL+   G + LCDFG  +L    +D+   +  T  Y APELL+G   Y  AVD W  G +  EML G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.3218</Hsp_bit-score>
      <Hsp_score>168</Hsp_score>
      <Hsp_evalue>9.08631e-16</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>279</Hsp_query-to>
      <Hsp_hit-from>504</Hsp_hit-from>
      <Hsp_hit-to>594</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>92</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLI</Hsp_qseq>
      <Hsp_hseq>IHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPE-IVNQKGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLI</Hsp_hseq>
      <Hsp_midline>IHRD+K +NIL+   G+VK+ DFGF   LT +  +    V T ++ APE +V    Y   VDVW+ G +  EM+ G   +     L  L+LI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>1.54209e-15</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>288</Hsp_query-to>
      <Hsp_hit-from>141</Hsp_hit-from>
      <Hsp_hit-to>235</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>95</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLITKT</Hsp_qseq>
      <Hsp_hseq>IHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIKS</Hsp_hseq>
      <Hsp_midline>IHRD+K  N+LIT  G VKLCDFG A  +     R      T ++ APE+++    Y   VD+W+ G    E+  GN  +     L  + LI K+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.5514</Hsp_bit-score>
      <Hsp_score>166</Hsp_score>
      <Hsp_evalue>1.91369e-15</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>294</Hsp_query-to>
      <Hsp_hit-from>150</Hsp_hit-from>
      <Hsp_hit-to>250</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>102</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTD-----YVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLITKTLG</Hsp_qseq>
      <Hsp_hseq>LHCDLKPKNLLVNSDCQLKICNFGLSCSYS-ENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFEGKDYVDHLNHILQILG</Hsp_hseq>
      <Hsp_midline>+H D+KP+N+L+     +K+C+FG +   + +  +  D     Y+ + WY+APE+L+   +   AVD+W+ GC+ AE+L    ++ G   +  L+ I + LG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>7.89903e-15</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>243</Hsp_query-to>
      <Hsp_hit-from>1155</Hsp_hit-from>
      <Hsp_hit-to>1252</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>98</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDR----------------YTDYVATRWYRAPELLVGDTQYGP--AVDVWAAGCVFAEMLCGNALW</Hsp_qseq>
      <Hsp_hseq>VHRDIKPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPW</Hsp_hseq>
      <Hsp_midline>+HRD+KPENIL+  +G++K  DFG AR + G   R                  + + T  Y APE + G    G   A DVWA GCV  EM  G   W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>1.07748e-14</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>231</Hsp_query-to>
      <Hsp_hit-from>464</Hsp_hit-from>
      <Hsp_hit-to>538</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>43</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>76</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCG</Hsp_qseq>
      <Hsp_hseq>IYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQG-YTKTVDWWTLGILLYEMMTG</Hsp_hseq>
      <Hsp_midline>I+RD+KPENIL+   G + LCDFG  +L     D+   +  T  Y APE+L+G   Y   VD W  G +  EM+ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>1.53532e-14</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>228</Hsp_query-to>
      <Hsp_hit-from>174</Hsp_hit-from>
      <Hsp_hit-to>247</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>75</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLC</Hsp_qseq>
      <Hsp_hseq>VHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFLKTS-CGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLC</Hsp_hseq>
      <Hsp_midline>+HRD+KPEN+L+ +H  VK+ DFG + ++T      T    +  Y APE++ G    GP VDVW+ G +   MLC</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>2.48649e-14</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>231</Hsp_query-to>
      <Hsp_hit-from>246</Hsp_hit-from>
      <Hsp_hit-to>333</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>89</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTD-------------YVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCG</Hsp_qseq>
      <Hsp_hseq>IHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELL-NDNYTDSRCDIWAFGCILYQMLAG</Hsp_hseq>
      <Hsp_midline>IHRD+KPENIL+ K+  VKL DFG A++L  +     D             +V T  Y +PELL  D       D+WA GC+  +ML G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>2.57679e-14</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>279</Hsp_query-to>
      <Hsp_hit-from>690</Hsp_hit-from>
      <Hsp_hit-to>780</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>92</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLI</Hsp_qseq>
      <Hsp_hseq>IHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPE-VVKQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLI</Hsp_hseq>
      <Hsp_midline>IHRD+K +N+L+     VK+ DFGF   LT +  +    V T ++ APE +V   +Y   +DVW+ G +  EML G   +     L  L+LI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>3.68462e-14</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>231</Hsp_query-to>
      <Hsp_hit-from>245</Hsp_hit-from>
      <Hsp_hit-to>319</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>76</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCG</Hsp_qseq>
      <Hsp_hseq>VHRDLKIENIMISSSGEIKIIDFGLSNIFDYRKQLHT-FCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCG</Hsp_hseq>
      <Hsp_midline>+HRD+K ENI+I+  G +K+ DFG + +   ++  +T +  + ++ APELL      GP VD+W+ G V   ++CG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YJL165C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:106894:109461:-1 gene:YJL165C transcript:YJL165C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HAL5 description:Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters; HAL5 has a paralog, KKQ8, that arose from the whole genome duplication [Source:SGD;Acc:S000003701]</Hit_def>
  <Hit_accession>YJL165C</Hit_accession>
  <Hit_len>855</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>4.5343e-14</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>243</Hsp_query-to>
      <Hsp_hit-from>686</Hsp_hit-from>
      <Hsp_hit-to>769</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>HRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDY----VATRWYRAPELLVGDTQYGPA-VDVWAAGCVFAEMLCGNALW</Hsp_qseq>
      <Hsp_hseq>HCDLKPENILFQPNGLLKICDFGTSSVFQTAWEKHVHFQSGAMGSEPYVAPEEFIRDAEYDPRLVDCWSCGIVYCTMVMGQYLW</Hsp_hseq>
      <Hsp_midline>H D+KPENIL   +G++K+CDFG + +     +++  +    + +  Y APE  + D +Y P  VD W+ G V+  M+ G  LW</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>7.9161e-14</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>231</Hsp_query-to>
      <Hsp_hit-from>266</Hsp_hit-from>
      <Hsp_hit-to>340</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>76</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCG</Hsp_qseq>
      <Hsp_hseq>VHRDLKIENIMISDSSEIKIIDFGLSNIYDSRKQLHT-FCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCG</Hsp_hseq>
      <Hsp_midline>+HRD+K ENI+I+    +K+ DFG + +   ++  +T +  + ++ APELL  +   GP VDVW+ G V   ++CG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YOR061W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:441534:442553:1 gene:YOR061W transcript:YOR061W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA2 description:Alpha&apos; catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000005587]</Hit_def>
  <Hit_accession>YOR061W</Hit_accession>
  <Hit_len>339</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>9.24043e-14</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>294</Hsp_query-to>
      <Hsp_hit-from>164</Hsp_hit-from>
      <Hsp_hit-to>261</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>99</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILIT-KHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGN-ALWPGNSDLHQLHLITKTLG</Hsp_qseq>
      <Hsp_hseq>MHRDVKPQNVMIDPTERKLRLIDWGLAEFYHPGVD-YNVRVASRYHKGPELLVNLNQYDYSLDLWSVGCMLAAIVFKKEPFFKGSSNPDQLVKIATVLG</Hsp_hseq>
      <Hsp_midline>+HRDVKP+N++I      ++L D+G A       D Y   VA+R+++ PELLV   QY  ++D+W+ GC+ A ++      + G+S+  QL  I   LG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YKL168C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:131288:133462:-1 gene:YKL168C transcript:YKL168C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KKQ8 description:Putative serine/threonine protein kinase with unknown cellular role; KKQ8 has a paralog, HAL5, that arose from the whole genome duplication [Source:SGD;Acc:S000001651]</Hit_def>
  <Hit_accession>YKL168C</Hit_accession>
  <Hit_len>724</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>3.04524e-13</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>243</Hsp_query-to>
      <Hsp_hit-from>561</Hsp_hit-from>
      <Hsp_hit-to>644</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>HRDVKPENILITKHGVVKLCDFGFARLL-TGQEDRY---TDYVATRWYRAPELLVGDTQYGPA-VDVWAAGCVFAEMLCGNALW</Hsp_qseq>
      <Hsp_hseq>HCDLKPENILFYPHGLLKICDFGTSSVFQTAWERRVHAQKGIIGSEPYVAPEEFVDGEYYDPRLIDCWSCGVVYITMILGHYLW</Hsp_hseq>
      <Hsp_midline>H D+KPENIL   HG++K+CDFG + +  T  E R       + +  Y APE  V    Y P  +D W+ G V+  M+ G+ LW</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>4.37245e-13</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>243</Hsp_query-to>
      <Hsp_hit-from>1387</Hsp_hit-from>
      <Hsp_hit-to>1500</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>114</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQ--------------------------------EDRYTDYVATRWYRAPELLVGDTQYGP--AVDVWAAGCVFAEMLCGNALW</Hsp_qseq>
      <Hsp_hseq>VHRDVKPENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPW</Hsp_hseq>
      <Hsp_midline>+HRDVKPENIL+  +GV+K  DFG A+ +                                   E+   D + T  Y APE + G T  G   A DVW+ GCV  EM+ G   W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>5.27985e-13</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>231</Hsp_query-to>
      <Hsp_hit-from>300</Hsp_hit-from>
      <Hsp_hit-to>385</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>87</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQED-----------RYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCG</Hsp_qseq>
      <Hsp_hseq>IHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELL-NDSFTDYRCDIWAFGCILFQMIAG</Hsp_hseq>
      <Hsp_midline>IHRD+KPENIL+     +KL DFG A+LL    +           R   +V T  Y +PELL  D+      D+WA GC+  +M+ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>5.28811e-13</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>258</Hsp_query-to>
      <Hsp_hit-from>328</Hsp_hit-from>
      <Hsp_hit-to>409</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>86</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFA-RLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSD</Hsp_qseq>
      <Hsp_hseq>IHRDIKPSNVLINSKGQIKLCDFGVSKKLINSIAD---TFVGTSTYMSPERIQGNV-YSIKGDVWSLGLMIIELVTGEFPLGGHND</Hsp_hseq>
      <Hsp_midline>IHRD+KP N+LI   G +KLCDFG + +L+    D    +V T  Y +PE + G+  Y    DVW+ G +  E++ G     G++D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YIL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:287790:288908:-1 gene:YIL035C transcript:YIL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA1 description:Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000001297]</Hit_def>
  <Hit_accession>YIL035C</Hit_accession>
  <Hit_len>372</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>8.75941e-13</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>294</Hsp_query-to>
      <Hsp_hit-from>192</Hsp_hit-from>
      <Hsp_hit-to>289</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>99</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILIT-KHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCG-NALWPGNSDLHQLHLITKTLG</Hsp_qseq>
      <Hsp_hseq>MHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNME-YNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLG</Hsp_hseq>
      <Hsp_midline>+HRDVKP N++I  K+  ++L D+G A       + Y   VA+R+++ PELLV    Y  ++D+W+ G + A M+      + G S+  QL  I K LG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>1.09914e-12</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>243</Hsp_query-to>
      <Hsp_hit-from>1300</Hsp_hit-from>
      <Hsp_hit-to>1380</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTD----YVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALW</Hsp_qseq>
      <Hsp_hseq>LHRDMKADNLLLDQDGICKISDFGISR---KSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPW</Hsp_hseq>
      <Hsp_midline>+HRD+K +N+L+ + G+ K+ DFG +R     +D Y++       T ++ APE++     Y   VD+W+ GC+  EM  G   W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>1.25491e-12</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>258</Hsp_query-to>
      <Hsp_hit-from>346</Hsp_hit-from>
      <Hsp_hit-to>425</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>87</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQ--EDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSD</Hsp_qseq>
      <Hsp_hseq>IHRDIKPQNILLNENGQVKLCDFG----VSGEAVNSLATTFTGTSFYMAPERIQGQP-YSVTSDVWSLGLTILEV--ANGKFPCSSE</Hsp_hseq>
      <Hsp_midline>IHRD+KP+NIL+ ++G VKLCDFG    ++G+      T +  T +Y APE + G   Y    DVW+ G    E+   N  +P +S+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>1.40636e-12</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>231</Hsp_query-to>
      <Hsp_hit-from>224</Hsp_hit-from>
      <Hsp_hit-to>297</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>76</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCG</Hsp_qseq>
      <Hsp_hseq>IHRDIKPENILIGFNNVIKLTDFGWS-IINPPENRRKTVCGTIDYLSPE-MVESREYDHTIDAWALGVLAFELLTG</Hsp_hseq>
      <Hsp_midline>IHRD+KPENILI  + V+KL DFG++ ++   E+R      T  Y +PE +V   +Y   +D WA G +  E+L G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>1.63125e-12</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>231</Hsp_query-to>
      <Hsp_hit-from>153</Hsp_hit-from>
      <Hsp_hit-to>228</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>43</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>77</Hsp_align-len>
      <Hsp_qseq>CIHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCG</Hsp_qseq>
      <Hsp_hseq>CVHRDLKLENILLDKNGNAKLTDFGFTRECMTKTTLET-VCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITG</Hsp_hseq>
      <Hsp_midline>C+HRD+K ENIL+ K+G  KL DFGF R    +    T    T  Y APEL+   T  G  +D+W+ G +   ++ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>3.08012e-12</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>231</Hsp_query-to>
      <Hsp_hit-from>168</Hsp_hit-from>
      <Hsp_hit-to>245</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>79</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILI---TKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCG</Hsp_qseq>
      <Hsp_hseq>VHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDG-HGKPCDIWSIGVITYTLLCG</Hsp_hseq>
      <Hsp_midline>+HRD+KPEN+L    +++  + + DFG A+ L G+ED       +  Y APE+L  D  +G   D+W+ G +   +LCG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>3.25526e-12</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>231</Hsp_query-to>
      <Hsp_hit-from>208</Hsp_hit-from>
      <Hsp_hit-to>279</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>76</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCG</Hsp_qseq>
      <Hsp_hseq>IYRDLKPENILLDKNGHIKITDFGFAKYVP---DVTYTLCGTPDYIAPE-VVSTKPYNKSVDWWSFGVLIYEMLAG</Hsp_hseq>
      <Hsp_midline>I+RD+KPENIL+ K+G +K+ DFGFA+ +    D       T  Y APE +V    Y  +VD W+ G +  EML G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>4.44843e-12</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>213</Hsp_query-to>
      <Hsp_hit-from>972</Hsp_hit-from>
      <Hsp_hit-to>1039</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>41</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>70</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVF</Hsp_qseq>
      <Hsp_hseq>VHRDIKDENVIVDSHGFVKLIDFGSAAYI--KSGPFDVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLL</Hsp_hseq>
      <Hsp_midline>+HRD+K EN+++  HG VKL DFG A  +  +   +  +V T  Y APE+L G +  G   D+WA G + </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.5362</Hsp_bit-score>
      <Hsp_score>140</Hsp_score>
      <Hsp_evalue>5.72631e-12</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>231</Hsp_query-to>
      <Hsp_hit-from>207</Hsp_hit-from>
      <Hsp_hit-to>278</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>76</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCG</Hsp_qseq>
      <Hsp_hseq>IYRDLKPENILLDKNGHIKITDFGFAKYVP---DVTYTLCGTPDYIAPE-VVSTKPYNKSIDWWSFGILIYEMLAG</Hsp_hseq>
      <Hsp_midline>I+RD+KPENIL+ K+G +K+ DFGFA+ +    D       T  Y APE +V    Y  ++D W+ G +  EML G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.5362</Hsp_bit-score>
      <Hsp_score>140</Hsp_score>
      <Hsp_evalue>6.32936e-12</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>285</Hsp_query-to>
      <Hsp_hit-from>576</Hsp_hit-from>
      <Hsp_hit-to>668</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>97</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLT---GQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLITK</Hsp_qseq>
      <Hsp_hseq>IHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPE-VVKQTATTAKADIWSTGCVVIEMFTGKHPFP---DFSQMQAIFK</Hsp_hseq>
      <Hsp_midline>IHRD+K  NILI   G VK+ DFG ++ L+    ++++      + ++ +PE +V  T      D+W+ GCV  EM  G   +P   D  Q+  I K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>1.01562e-11</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>258</Hsp_query-to>
      <Hsp_hit-from>339</Hsp_hit-from>
      <Hsp_hit-to>418</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>87</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQ--EDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSD</Hsp_qseq>
      <Hsp_hseq>IHRDIKPQNILLNEKGEIKLCDFG----VSGEAVNSLAMTFTGTSFYMAPERIQGQP-YSVTCDVWSLGLTLLEVAGGR--FPFESD</Hsp_hseq>
      <Hsp_midline>IHRD+KP+NIL+ + G +KLCDFG    ++G+        +  T +Y APE + G   Y    DVW+ G    E+  G   +P  SD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>2.01575e-11</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>243</Hsp_query-to>
      <Hsp_hit-from>140</Hsp_hit-from>
      <Hsp_hit-to>222</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>43</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>83</Hsp_align-len>
      <Hsp_qseq>HRDVKPENILITKHGVVKLCDFGFA---RLLTGQEDRYTDYVATRWYRAPELLVGDT-QYGPAVDVWAAGCVFAEMLCGNALW</Hsp_qseq>
      <Hsp_hseq>HRDIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQTPW</Hsp_hseq>
      <Hsp_midline>HRD+KPENIL+ K+G +KL DFG A   R   G      D   +  Y APE+L  +   Y    D+W+ G +   +L G   W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>3.02909e-11</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>231</Hsp_query-to>
      <Hsp_hit-from>190</Hsp_hit-from>
      <Hsp_hit-to>261</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>76</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCG</Hsp_qseq>
      <Hsp_hseq>IYRDLKPENILLDRNGHIKITDFGFAKEV--QTVTWT-LCGTPDYIAPEVIT-TKPYNKSVDWWSLGVLIYEMLAG</Hsp_hseq>
      <Hsp_midline>I+RD+KPENIL+ ++G +K+ DFGFA+ +  Q   +T    T  Y APE++     Y  +VD W+ G +  EML G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>3.66148e-11</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>285</Hsp_query-to>
      <Hsp_hit-from>832</Hsp_hit-from>
      <Hsp_hit-to>934</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>108</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFAR--------------LLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLITK</Hsp_qseq>
      <Hsp_hseq>IHRDLKPMNIFIDESRNVKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVLDGTGHYNEKIDMYSLGIIFFEM-----IYPFSTGMERVNILKK</Hsp_hseq>
      <Hsp_midline>IHRD+KP NI I +   VK+ DFG A+               L G  D  T  + T  Y A E+L G   Y   +D+++ G +F EM     ++P ++ + +++++ K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>5.17325e-11</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>258</Hsp_query-to>
      <Hsp_hit-from>946</Hsp_hit-from>
      <Hsp_hit-to>1029</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>85</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSD</Hsp_qseq>
      <Hsp_hseq>IYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEIL-KEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDE</Hsp_hseq>
      <Hsp_midline>I+RD+K ENIL+T  G +K+ D+G  +      +R + +  T  + APE+L  + +Y  AVD WA G +  +ML   + + G+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>5.41155e-11</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>279</Hsp_query-to>
      <Hsp_hit-from>135</Hsp_hit-from>
      <Hsp_hit-to>242</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>109</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARL----LTGQEDRY-------------TDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLI</Hsp_qseq>
      <Hsp_hseq>IHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYN-QCGYGSDIWALGCMIYQFVQGQPPFRGENELKTFEKI</Hsp_hseq>
      <Hsp_midline>IHRD+KPEN+L+ + G + + DFG A      L+G   ++               +V T  Y +PELL+ + Q G   D+WA GC+  + + G   + G ++L     I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>6.84982e-11</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>288</Hsp_query-to>
      <Hsp_hit-from>172</Hsp_hit-from>
      <Hsp_hit-to>274</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>103</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQY-GPAVDVWAAGCVFAEMLCGNALW------PGNSDLHQLH-LITKT</Hsp_qseq>
      <Hsp_hseq>VHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARLYKYITQT</Hsp_hseq>
      <Hsp_midline>+HRD+K EN+L+ KH  + + DFGF        +       +  Y APEL+V    Y     DVW+ G +   ML G   W      P   D+ +L+  IT+T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>1.02676e-10</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>231</Hsp_query-to>
      <Hsp_hit-from>149</Hsp_hit-from>
      <Hsp_hit-to>223</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>41</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>76</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCG</Hsp_qseq>
      <Hsp_hseq>VHRDLKPENLLLDSFYNIKIADFGMAALQT-DADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTG</Hsp_hseq>
      <Hsp_midline>+HRD+KPEN+L+     +K+ DFG A L T   D       +  Y APE++ G    G A DVW+ G +   +L G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YAR018C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:170396:171703:-1 gene:YAR018C transcript:YAR018C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN3 description:Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol [Source:SGD;Acc:S000000071]</Hit_def>
  <Hit_accession>YAR018C</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>1.65746e-10</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>222</Hsp_query-to>
      <Hsp_hit-from>171</Hsp_hit-from>
      <Hsp_hit-to>281</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>112</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILIT-------------------------------KHG--------VVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEM</Hsp_qseq>
      <Hsp_hseq>IHRDLKPGNIFLSYDDSDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLAKSLETSIQFATTYVGTPYYMSPEVLM-DQPYSPLSDIWSLGCVIFEM</Hsp_hseq>
      <Hsp_midline>IHRD+KP NI ++                               K G        VVKL DFG A+ L       T YV T +Y +PE+L+ D  Y P  D+W+ GCV  EM</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>2.15149e-10</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>243</Hsp_query-to>
      <Hsp_hit-from>447</Hsp_hit-from>
      <Hsp_hit-to>529</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>HRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDY----VATRWYRAPELLVGDTQYGP-AVDVWAAGCVFAEMLCGNALW</Hsp_qseq>
      <Hsp_hseq>HRDLKPENLLLTHDGVLKITDFGNSECFKMAWEKNIHLSGGVCGSSPYIAPEEYIKE-EFDPRPVDIWACGVIYMAMRTGRQLW</Hsp_hseq>
      <Hsp_midline>HRD+KPEN+L+T  GV+K+ DFG +       ++          +  Y APE  + + ++ P  VD+WA G ++  M  G  LW</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>2.55709e-10</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>231</Hsp_query-to>
      <Hsp_hit-from>138</Hsp_hit-from>
      <Hsp_hit-to>213</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>44</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>77</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQ-YGPAVDVWAAGCVFAEMLCG</Hsp_qseq>
      <Hsp_hseq>IHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRDT-FVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKG</Hsp_hseq>
      <Hsp_midline>IHRD+K  NIL+ + G+VKL DFG +  +     R T +V T ++ APE++  +   Y    D+W+ G    E+L G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YLL019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:105686:107899:-1 gene:YLL019C transcript:YLL019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KNS1 description:Protein kinase involved in negative regulation of PolIII transcription; effector kinase of the TOR signaling pathway and phosphorylates Rpc53p to regulate ribosome and tRNA biosynthesis; member of the LAMMER family of protein kinases, which are serine/threonine kinases also capable of phosphorylating tyrosine residues; capable of autophosphorylation [Source:SGD;Acc:S000003942]</Hit_def>
  <Hit_accession>YLL019C</Hit_accession>
  <Hit_len>737</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>2.90128e-10</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>294</Hsp_query-to>
      <Hsp_hit-from>437</Hsp_hit-from>
      <Hsp_hit-to>561</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>129</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILIT--------------------------------KHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLITKTLG</Hsp_qseq>
      <Hsp_hseq>IHTDLKPENILICDETHIAQKLPLKTVQSLSKRRREASKGKRKILKNPEIKIIDFGSAIF---HYEYHPPVISTRHYRAPEIVLGLGWSFPC-DIWSIACVLVELVIGESLYPIHENLEHMAMMQRING</Hsp_hseq>
      <Hsp_midline>IH D+KPENILI                                 K+  +K+ DFG A       + +   ++TR YRAPE+++G     P  D+W+  CV  E++ G +L+P + +L  + ++ +  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>4.02721e-10</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>231</Hsp_query-to>
      <Hsp_hit-from>153</Hsp_hit-from>
      <Hsp_hit-to>227</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>42</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>76</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCG</Hsp_qseq>
      <Hsp_hseq>VHRDLKPENLLLDHKYNIKIADFGMAALETEGKLLETS-CGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTG</Hsp_hseq>
      <Hsp_midline>+HRD+KPEN+L+     +K+ DFG A L T  +   T    +  Y APE++ G    G A DVW+ G +   +L G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>6.28552e-10</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>204</Hsp_query-to>
      <Hsp_hit-from>1227</Hsp_hit-from>
      <Hsp_hit-to>1291</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>26</Hsp_identity>
      <Hsp_positive>39</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>67</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAG</Hsp_qseq>
      <Hsp_hseq>VHRDIKDENVIVDSKGFVKIIDFGSAAYV--KSGPFDVFVGTIDYAAPEVLGGNPYEGQPQDIWAIG</Hsp_hseq>
      <Hsp_midline>+HRD+K EN+++   G VK+ DFG A  +  +   +  +V T  Y APE+L G+   G   D+WA G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>6.99871e-10</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>261</Hsp_query-to>
      <Hsp_hit-from>187</Hsp_hit-from>
      <Hsp_hit-to>282</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>96</Hsp_align-len>
      <Hsp_qseq>HRDVKPENILITKHGVVKLCDFGFA-RLLTGQEDRYTDY--------VATRWYRAPELLVGDTQY--GPAVDVWAAGCVFAEMLCGNALWPGNSDL</Hsp_qseq>
      <Hsp_hseq>HRDIKPSNLLISSNGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPFNANSGL</Hsp_hseq>
      <Hsp_midline>HRD+KP N+LI+ +G VK+ DFG A    TG  +  + +        + T  + APEL   + +Y    A+D+W+ G     +L G   +  NS L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>7.43852e-10</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>255</Hsp_query-to>
      <Hsp_hit-from>317</Hsp_hit-from>
      <Hsp_hit-to>412</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>97</Hsp_align-len>
      <Hsp_qseq>HRDVKPENILITKHG--VVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVG-DT-----------QYGPAVDVWAAGCVFAEMLCGNALWPGNS</Hsp_qseq>
      <Hsp_hseq>HRDLKPDNILIEQDDPVLVKITDFGLAKV-QGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGST</Hsp_hseq>
      <Hsp_midline>HRD+KP+NILI +    +VK+ DFG A++  G       +  T  Y APE++ G DT           +Y   VD+W+ GC+   +L G+  + G++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>9.67538e-10</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>285</Hsp_query-to>
      <Hsp_hit-from>446</Hsp_hit-from>
      <Hsp_hit-to>557</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>113</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQED------------------RYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPG-NSDLHQLHLITK</Hsp_qseq>
      <Hsp_hseq>IYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNG-HTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTK</Hsp_hseq>
      <Hsp_midline>I+RD+KPENIL+ + G V L DF  +   TG +                   R   +V T  Y APE++ G+  +  AVD W  G +  EML G   + G NS+    +++TK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>1.02569e-09</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>231</Hsp_query-to>
      <Hsp_hit-from>158</Hsp_hit-from>
      <Hsp_hit-to>235</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>42</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>79</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILI---TKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCG</Hsp_qseq>
      <Hsp_hseq>VHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDG-HGKPCDIWSIGVITYTLLCG</Hsp_hseq>
      <Hsp_midline>+HRD+KPEN+L    +    + + DFG A+ L   E+       +  Y APE+L  D  +G   D+W+ G +   +LCG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>1.89895e-09</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>273</Hsp_query-to>
      <Hsp_hit-from>172</Hsp_hit-from>
      <Hsp_hit-to>268</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>97</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQY-GPAVDVWAAGCVFAEMLCGNALW------PGNSDLHQLH</Hsp_qseq>
      <Hsp_hseq>VHRDLKLENLLLDKNENLVITDFGFVNEFCSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGRLY</Hsp_hseq>
      <Hsp_midline>+HRD+K EN+L+ K+  + + DFGF      + +       +  Y APEL++    Y     D+W+ G +   +L G   W      P  SD+ +L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>2.1292e-09</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>258</Hsp_query-to>
      <Hsp_hit-from>237</Hsp_hit-from>
      <Hsp_hit-to>318</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>85</Hsp_align-len>
      <Hsp_qseq>HRDVKPENILITKHGV-VKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSD</Hsp_qseq>
      <Hsp_hseq>HRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTS-CGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHL--PFNDD</Hsp_hseq>
      <Hsp_midline>HRD+KPEN+L+ K    +K+ DFG A L    +   T    +  Y +PE+++G   +G   DVW+ G V   +L G+   P N D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>2.6856e-09</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>312</Hsp_query-to>
      <Hsp_hit-from>576</Hsp_hit-from>
      <Hsp_hit-to>671</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>53</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>104</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNSDL-HQLHLITKTLGDLRSRG</Hsp_qseq>
      <Hsp_hseq>VHLDLKPANVMITFEGNLKLGDFGMATHLP-LEDKSFENEGDREYIAPE-IISDCTYDYKADIFSLGLMIVE-IAANVVLPDNGNAWHKLR-----SGDLSDAG</Hsp_hseq>
      <Hsp_midline>+H D+KP N++IT  G +KL DFG A  L   ED+  +    R Y APE ++ D  Y    D+++ G +  E +  N + P N +  H+L       GDL   G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YOR267C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:822588:824867:-1 gene:YOR267C transcript:YOR267C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRK1 description:Protein kinase; implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005793]</Hit_def>
  <Hit_accession>YOR267C</Hit_accession>
  <Hit_len>759</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>2.91574e-09</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>258</Hsp_query-to>
      <Hsp_hit-from>338</Hsp_hit-from>
      <Hsp_hit-to>428</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>91</Hsp_align-len>
      <Hsp_qseq>HRDVKPENILITKHGVVKLCDFGFARLLTGQ-EDRYT---DYVATRWYRAPELLVGDTQYGP-AVDVWAAGCVFAEMLCGNALW--PGNSD</Hsp_qseq>
      <Hsp_hseq>HRDLKLDNCVMTSQGILKLIDFGSAVVFRYPFEDGVTMAHGIVGSDPYLAPEVITSTKSYDPQCVDIWSIGIIYCCMVLKRFPWKAPRDSD</Hsp_hseq>
      <Hsp_midline>HRD+K +N ++T  G++KL DFG A +     ED  T     V +  Y APE++     Y P  VD+W+ G ++  M+     W  P +SD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>4.11204e-09</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>231</Hsp_query-to>
      <Hsp_hit-from>325</Hsp_hit-from>
      <Hsp_hit-to>417</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>44</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>95</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENIL--ITKHG-----------------VVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCG</Hsp_qseq>
      <Hsp_hseq>IHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAK-FTGEMQFTNTLCGTPSYVAPEVLT-KKGYTSKVDLWSAGVILYVCLCG</Hsp_hseq>
      <Hsp_midline>IHRD+KPENIL  IT+                    VK+ DFG A+  TG+         T  Y APE+L     Y   VD+W+AG +    LCG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>7.14477e-09</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>231</Hsp_query-to>
      <Hsp_hit-from>169</Hsp_hit-from>
      <Hsp_hit-to>263</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>97</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITK-----HG----------------VVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCG</Hsp_qseq>
      <Hsp_hseq>VHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAET-LCGSPLYMAPEIL-NYQKYNAKADLWSVGTVVFEMCCG</Hsp_hseq>
      <Hsp_midline>+HRD+KP+N+L++      H                 ++K+ DFGFAR L       T    +  Y APE+L    +Y    D+W+ G V  EM CG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>71</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>7.52132e-09</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>231</Hsp_query-to>
      <Hsp_hit-from>201</Hsp_hit-from>
      <Hsp_hit-to>277</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>42</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>77</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGD-TQYGPAVDVWAAGCVFAEMLCG</Hsp_qseq>
      <Hsp_hseq>IHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIG</Hsp_hseq>
      <Hsp_midline>IHRD+K  NI    +  +K+ DFG A +L  + +R      T  Y APE+L+G  + +   VD+W+ G +   +L G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>72</Hit_num>
  <Hit_id>YDL214C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:74446:76545:-1 gene:YDL214C transcript:YDL214C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR2 description:Serine/threonine protein kinase; inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance; PRR2 has a paralog, NPR1, that arose from the whole genome duplication [Source:SGD;Acc:S000002373]</Hit_def>
  <Hit_accession>YDL214C</Hit_accession>
  <Hit_len>699</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>8.36499e-09</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>243</Hsp_query-to>
      <Hsp_hit-from>482</Hsp_hit-from>
      <Hsp_hit-to>564</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>HRDVKPENILITKHGVVKLCDFG----FARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGP-AVDVWAAGCVFAEMLCGNALW</Hsp_qseq>
      <Hsp_hseq>HRDLKLDNCVVTRRGILKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFYFN-EYDPRALDVWSVGIIFFCMITRRFPW</Hsp_hseq>
      <Hsp_midline>HRD+K +N ++T+ G++KL DFG    F   L+ Q       V +  Y +PE+   + +Y P A+DVW+ G +F  M+     W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>73</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>1.20608e-08</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>246</Hsp_query-to>
      <Hsp_hit-from>482</Hsp_hit-from>
      <Hsp_hit-to>565</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>40</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>86</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILIT-KHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVG----DTQYGPAVDVWAAGCVFAEMLCGNALWP</Hsp_qseq>
      <Hsp_hseq>IHRDVKPTNILCSANQGTVKLCDFGVSGNLVASLAKTN--IGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYP</Hsp_hseq>
      <Hsp_midline>IHRDVKP NIL +   G VKLCDFG +  L     +    +  + Y APE +         Y    D+W+ G    EM  G   +P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>74</Hit_num>
  <Hit_id>YDL025C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:405344:407206:-1 gene:YDL025C transcript:YDL025C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RTK1 description:Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002183]</Hit_def>
  <Hit_accession>YDL025C</Hit_accession>
  <Hit_len>620</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>1.55815e-08</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>243</Hsp_query-to>
      <Hsp_hit-from>428</Hsp_hit-from>
      <Hsp_hit-to>510</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>HRDVKPENILITKHGVVKLCDFGFARLLT-GQED---RYTDYVATRWYRAPELLVGDTQYGPAV-DVWAAGCVFAEMLCGNALW</Hsp_qseq>
      <Hsp_hseq>HRDLKLDNCVVTKDGILKLIDFGSAVVFQYPYEDTIVKSHGIVGSDPYLAPELL-KQTSYDPRVADVWSIAIIFYCMVLKRFPW</Hsp_hseq>
      <Hsp_midline>HRD+K +N ++TK G++KL DFG A +     ED   +    V +  Y APELL   T Y P V DVW+   +F  M+     W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>75</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>1.7748e-08</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>243</Hsp_query-to>
      <Hsp_hit-from>131</Hsp_hit-from>
      <Hsp_hit-to>222</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>96</Hsp_align-len>
      <Hsp_qseq>HRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDY-VATRWYRAPELLVG-----------DTQYGP-----AVDVWAAGCVFAEMLCGNALW</Hsp_qseq>
      <Hsp_hseq>HRDIKPENILLTINGDIKLADWGHAI----QSPKSNDFQIGTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFGDCLF</Hsp_hseq>
      <Hsp_midline>HRD+KPENIL+T +G +KL D+G A     Q  +  D+ + T  YRAPE   G           D    P       D W+ G     ++ G+ L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>76</Hit_num>
  <Hit_id>YMR216C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:698811:701039:-1 gene:YMR216C transcript:YMR216C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKY1 description:SR protein kinase (SRPK); involved in regulating proteins involved in mRNA metabolism and cation homeostasis; similar to human SRPK1 [Source:SGD;Acc:S000004829]</Hit_def>
  <Hit_accession>YMR216C</Hit_accession>
  <Hit_len>742</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>1.92087e-08</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>306</Hsp_query-to>
      <Hsp_hit-from>540</Hsp_hit-from>
      <Hsp_hit-to>631</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>101</Hsp_align-len>
      <Hsp_qseq>PENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALW---PGNS---DLHQLHLITKTLGDLRS</Hsp_qseq>
      <Hsp_hseq>PENLI-----QIKIADLGNA---CWYDEHYTNSIQTREYRSPEVLLG-APWGCGADIWSTACLIFELITGDFLFEPDEGHSYTKDDDHIAQIIELLGELPS</Hsp_hseq>
      <Hsp_midline>PEN++      +K+ D G A      ++ YT+ + TR YR+PE+L+G   +G   D+W+  C+  E++ G+ L+    G+S   D   +  I + LG+L S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>77</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>2.64232e-08</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>255</Hsp_query-to>
      <Hsp_hit-from>274</Hsp_hit-from>
      <Hsp_hit-to>366</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>96</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTD------------YVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNS</Hsp_qseq>
      <Hsp_hseq>VYRDLKPENCLLNQRGHLVLTDFGLSK--KSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKA-YSQNCDWYSLGCLLYDMLVGKPPYTGSN</Hsp_hseq>
      <Hsp_midline>++RD+KPEN L+ + G + L DFG ++      D   D             + T  Y APE+L+G   Y    D ++ GC+  +ML G   + G++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>78</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>3.46994e-08</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>234</Hsp_query-to>
      <Hsp_hit-from>143</Hsp_hit-from>
      <Hsp_hit-to>215</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>38</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>77</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGN</Hsp_qseq>
      <Hsp_hseq>IHRDIKAANILLSADNTVKLADFGVSTIVNSSA---LTLAGTLNWMAPEIL-GNRGASTLSDIWSLGATVVEMLTKN</Hsp_hseq>
      <Hsp_midline>IHRD+K  NIL++    VKL DFG + ++            T  + APE+L G+       D+W+ G    EML  N</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>79</Hit_num>
  <Hit_id>YNL183C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:293137:295509:-1 gene:YNL183C transcript:YNL183C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NPR1 description:Protein kinase; stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p; negatively regulates Ldb19p-mediated endocytosis through phosphorylation of Ldb19p, which prevents its association with the plasma membrane; Npr1p activity is negatively regulated via phosphorylation by the TOR complex; NPR1 has a paralog, PRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005127]</Hit_def>
  <Hit_accession>YNL183C</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.9802</Hsp_bit-score>
      <Hsp_score>110</Hsp_score>
      <Hsp_evalue>6.44431e-08</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>243</Hsp_query-to>
      <Hsp_hit-from>559</Hsp_hit-from>
      <Hsp_hit-to>641</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>HRDVKPENILITKHGVVKLCDFG----FARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGP-AVDVWAAGCVFAEMLCGNALW</Hsp_qseq>
      <Hsp_hseq>HRDLKLDNCVINEKGIVKLIDFGAAVVFSYPFSKNLVEASGIVGSDPYLAPEVCIF-AKYDPRPVDIWSSAIIFACMILKKFPW</Hsp_hseq>
      <Hsp_midline>HRD+K +N +I + G+VKL DFG    F+   +      +  V +  Y APE+ +   +Y P  VD+W++  +FA M+     W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>80</Hit_num>
  <Hit_id>YIL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:183937:186369:1 gene:YIL095W transcript:YIL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRK1 description:Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton and reduces endocytic ability of cell through the phosphorylation of the Pan1p-Sla1p-End3p protein complex; PRK1 has a paralog, ARK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001357]</Hit_def>
  <Hit_accession>YIL095W</Hit_accession>
  <Hit_len>810</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.9802</Hsp_bit-score>
      <Hsp_score>110</Hsp_score>
      <Hsp_evalue>8.07335e-08</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>228</Hsp_query-to>
      <Hsp_hit-from>155</Hsp_hit-from>
      <Hsp_hit-to>239</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>88</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLL-----TGQEDRYTDY----VATRWYRAPELLVGDTQYGPAV----DVWAAGCVFAEMLC</Hsp_qseq>
      <Hsp_hseq>IHRDIKIENVLISHDGLYKVCDFGSVSGVIRPPRNTQEFNYVQHDILTNTTAQYRSPEMI--DLYRGLPIDEKSDIWALG-VFLYKIC</Hsp_hseq>
      <Hsp_midline>IHRD+K EN+LI+  G+ K+CDFG    +       QE  Y  +      T  YR+PE++  D   G  +    D+WA G VF   +C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>81</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.595</Hsp_bit-score>
      <Hsp_score>109</Hsp_score>
      <Hsp_evalue>9.96967e-08</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>231</Hsp_query-to>
      <Hsp_hit-from>310</Hsp_hit-from>
      <Hsp_hit-to>416</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>43</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>110</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILI----------------------TKHGVV------------KLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCG</Hsp_qseq>
      <Hsp_hseq>VHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKNTKTP--CGTVGYTAPEV-VKDEHYSMKVDMWGIGCVLYTMLCG</Hsp_hseq>
      <Hsp_midline>+HRD+KPEN+L                          G+             KL DFG ++ +  +  +      T  Y APE+ V D  Y   VD+W  GCV   MLCG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>82</Hit_num>
  <Hit_id>YJR059W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:545787:548243:1 gene:YJR059W transcript:YJR059W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK2 description:Serine/threonine protein kinase; involved in regulation of ion transport across plasma membrane; carboxyl terminus is essential for glucose-dependent Pma1p activation via phosphorylation of Pma1p-Ser899; enhances spermine uptake; PTK2 has a paralog, PTK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003820]</Hit_def>
  <Hit_accession>YJR059W</Hit_accession>
  <Hit_len>818</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.8246</Hsp_bit-score>
      <Hsp_score>107</Hsp_score>
      <Hsp_evalue>1.58025e-07</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>225</Hsp_query-to>
      <Hsp_hit-from>386</Hsp_hit-from>
      <Hsp_hit-to>476</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>43</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>91</Hsp_align-len>
      <Hsp_qseq>HRDVKPENILITKHGVVKLCDFGFARLLTGQEDRYTDYVATRW-------YRAPELLVGDTQ----------YGP-AVDVWAAGCVFAEML</Hsp_qseq>
      <Hsp_hseq>HRDLKPENVLISKEGICKLTDFGISDWYHVIPHDYTSPVKTCQGMIGSPPYTPPEVMYFDAKKHYPEKFQKPYNPLAMDSYALGIMLITMI</Hsp_hseq>
      <Hsp_midline>HRD+KPEN+LI+K G+ KL DFG +         YT  V T         Y  PE++  D +          Y P A+D +A G +   M+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>83</Hit_num>
  <Hit_id>YNL020C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:595623:597539:-1 gene:YNL020C transcript:YNL020C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ARK1 description:Serine/threonine protein kinase; involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis; ARK1 has a paralog, PRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004965]</Hit_def>
  <Hit_accession>YNL020C</Hit_accession>
  <Hit_len>638</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.8246</Hsp_bit-score>
      <Hsp_score>107</Hsp_score>
      <Hsp_evalue>1.95801e-07</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>228</Hsp_query-to>
      <Hsp_hit-from>156</Hsp_hit-from>
      <Hsp_hit-to>240</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>90</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFA-----------RLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAV----DVWAAGCVFAEMLC</Hsp_qseq>
      <Hsp_hseq>IHRDIKIENVLISANNEYKLCDFGSVCGIIRPPRNSQELSYVQQDILKNTTAQ--YRSPEMI--DTFRGLPIDEKSDIWALG-IFLYKLC</Hsp_hseq>
      <Hsp_midline>IHRD+K EN+LI+ +   KLCDFG              L   Q+D   +  A   YR+PE++  DT  G  +    D+WA G +F   LC</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>84</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.4394</Hsp_bit-score>
      <Hsp_score>106</Hsp_score>
      <Hsp_evalue>2.32186e-07</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>255</Hsp_query-to>
      <Hsp_hit-from>618</Hsp_hit-from>
      <Hsp_hit-to>721</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>105</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFA--------RLLTGQED-------------RYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCGNALWPGNS</Hsp_qseq>
      <Hsp_hseq>IYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRGNG-HTAAVDWWTLGILIYEMLFGFTPFKGDN</Hsp_hseq>
      <Hsp_midline>I+RD+KPENIL+ + G + L DF  +         ++ G                R   +V T  Y APE++ G+  +  AVD W  G +  EML G   + G++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>85</Hit_num>
  <Hit_id>YFL029C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:78055:79161:-1 gene:YFL029C transcript:YFL029C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CAK1 description:Cyclin-dependent kinase-activating kinase; required for passage through the cell cycle; phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases [Source:SGD;Acc:S000001865]</Hit_def>
  <Hit_accession>YFL029C</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.0542</Hsp_bit-score>
      <Hsp_score>105</Hsp_score>
      <Hsp_evalue>2.89413e-07</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>198</Hsp_query-to>
      <Hsp_hit-from>153</Hsp_hit-from>
      <Hsp_hit-to>229</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>26</Hsp_identity>
      <Hsp_positive>42</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>78</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGV-----VKLCDFGFARLLTGQ--------EDRYTDYVATRWYRAPELLVGDTQYGPAVDVWA</Hsp_qseq>
      <Hsp_hseq>IHRDIKPQNIMLTNNTSTVSPKLYIIDFGISYDMANNSQTSAEPMDSKVTD-ISTGIYKAPEVLFGVKCYDGGVDVWS</Hsp_hseq>
      <Hsp_midline>IHRD+KP+NI++T +       + + DFG +  +           + + TD ++T  Y+APE+L G   Y   VDVW+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>86</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>44.2838</Hsp_bit-score>
      <Hsp_score>103</Hsp_score>
      <Hsp_evalue>6.72241e-07</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>297</Hsp_query-to>
      <Hsp_hit-from>274</Hsp_hit-from>
      <Hsp_hit-to>394</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>124</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFA----------RLLTGQEDRYTDYVATRWYRAPELLVGD---TQYGPA-------------VDVWAAGCVFAEMLCGNALWPGNSDLHQLHLITKTLGD</Hsp_qseq>
      <Hsp_hseq>IHRDIKPANLLISGDGTVKISDFGVSLAASSTNSSDSSESLDELELAKTVGTPAFFAPEMCLGEDAFTRYNLTKENLFRGSCISFMIDIWAVGVTLYCLLFG--MLPFFSDF-ELKLFEKIVND</Hsp_hseq>
      <Hsp_midline>IHRD+KP N+LI+  G VK+ DFG +             +  E      V T  + APE+ +G+   T+Y                +D+WA G     +L G  + P  SD  +L L  K + D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>87</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>43.5134</Hsp_bit-score>
      <Hsp_score>101</Hsp_score>
      <Hsp_evalue>1.21526e-06</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>231</Hsp_query-to>
      <Hsp_hit-from>256</Hsp_hit-from>
      <Hsp_hit-to>352</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>44</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>100</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENIL---ITKHGV---------------------VKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQYGPAVDVWAAGCVFAEMLCG</Hsp_qseq>
      <Hsp_hseq>VHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLRNNTAKTP--CGTIEYVASEVFT-SKRYSMKVDMWSIGCVLFTLLCG</Hsp_hseq>
      <Hsp_midline>+HRDVKPEN+L   I  +G+                     VKL DFG A+ L     +      T  Y A E+     +Y   VD+W+ GCV   +LCG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>88</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>43.5134</Hsp_bit-score>
      <Hsp_score>101</Hsp_score>
      <Hsp_evalue>1.32063e-06</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>225</Hsp_query-to>
      <Hsp_hit-from>205</Hsp_hit-from>
      <Hsp_hit-to>283</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>41</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>82</Hsp_align-len>
      <Hsp_qseq>HRDVKPENILITK-HGVVKLCDFGFARLLTGQEDRYTDYVATRWYRAPELLVGDTQ-------YGPA-VDVWAAGCVFAEML</Hsp_qseq>
      <Hsp_hseq>HRDIKPENILISGIDWTIKLTDWGLATTDKTSMDR---NVGSERYMSPELFDSNLDIKERKEPYDCAKVDLWAMGIVFLNIV</Hsp_hseq>
      <Hsp_midline>HRD+KPENILI+     +KL D+G A       DR    V +  Y +PEL   +         Y  A VD+WA G VF  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>89</Hit_num>
  <Hit_id>YDL028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:400997:403291:-1 gene:YDL028C transcript:YDL028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MPS1 description:Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]</Hit_def>
  <Hit_accession>YDL028C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>42.743</Hsp_bit-score>
      <Hsp_score>99</Hsp_score>
      <Hsp_evalue>2.04767e-06</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>231</Hsp_query-to>
      <Hsp_hit-from>560</Hsp_hit-from>
      <Hsp_hit-to>650</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>93</Hsp_align-len>
      <Hsp_qseq>IHRDVKPENILITKHGVVKLCDFGFARLL---TGQEDRYTDYVATRWYRAPELLVG-------DTQY-------GPAVDVWAAGCVFAEMLCG</Hsp_qseq>
      <Hsp_hseq>VHSDLKPANFVLVK-GILKIIDFGIANAVPEHTVNIYRETQ-IGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYG</Hsp_hseq>
      <Hsp_midline>+H D+KP N ++ K G++K+ DFG A  +   T    R T  + T  Y APE LV        + Q+       G   D+W+ GC+  +M+ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>90</Hit_num>
  <Hit_id>YKL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:347214:349136:-1 gene:YKL048C transcript:YKL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ELM1 description:Serine/threonine protein kinase; regulates the orientation checkpoint, the morphogenesis checkpoint and the metabolic switch from fermentative to oxidative metabolism by phosphorylating the activation loop of Kin4p, Hsl1p and Snf4p respectively; cooperates with Hsl7p in recruiting Hsl1p to the septin ring, a prerequisite for subsequent recruitment, phosphorylation, and degradation of Swe1p; forms part of the bud neck ring; regulates cytokinesis [Source:SGD;Acc:S000001531]</Hit_def>
  <Hit_accession>YKL048C</Hit_accession>
  <Hit_len>640</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>42.3578</Hsp_bit-score>
      <Hsp_score>98</Hsp_score>
      <Hsp_evalue>2.5499e-06</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>285</Hsp_query-to>
      <Hsp_hit-from>255</Hsp_hit-from>
      <Hsp_hit-to>368</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>115</Hsp_align-len>
      <Hsp_qseq>CIHRDVKPENILI-TKHGVVKLCDFGFARLLTGQEDRYTD-------------YVATRWYRAPELL-VGDTQY-----GPAVDVWAAGCVFAEMLCGNALWPGNSDLHQLHLITK</Hsp_qseq>
      <Hsp_hseq>CIHRDIKPSNILLDEEEKVAKLSDFG-SCIFTPQSLPFSDANFEDCFQRELNKIVGTPAFIAPELCHLGNSKRDFVTDGFKLDIWSLGVTLYCLLYNELPFFGENEFETYHKIIE</Hsp_hseq>
      <Hsp_midline>CIHRD+KP NIL+  +  V KL DFG + + T Q   ++D              V T  + APEL  +G+++      G  +D+W+ G     +L     + G ++    H I +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>76</Statistics_hsp-len>
      <Statistics_eff-space>72374010</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0034354-RA transcript Note:&quot;Similar to CDKL1 Cyclin-dependent kinase-like 1 (Homo sapiens)&quot; offset:0 AED:0.26 eAED:0.26 QI:0|0|0|1|0|0|2|72|71</Iteration_query-def>
  <Iteration_query-len>288</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>67</Statistics_hsp-len>
      <Statistics_eff-space>71684143</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055113-RA transcript Note:&quot;Similar to LBR Delta(14)-sterol reductase LBR (Gallus gallus)&quot; offset:199 AED:0.15 eAED:0.15 QI:199|0.75|1|1|0.12|0.44|9|556|337</Iteration_query-def>
  <Iteration_query-len>1769</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YNL280C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:109095:110411:-1 gene:YNL280C transcript:YNL280C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ERG24 description:C-14 sterol reductase; acts in ergosterol biosynthesis; mutants accumulate the abnormal sterol ignosterol (ergosta-8,14 dienol), and are viable under anaerobic growth conditions but inviable on rich medium under aerobic conditions [Source:SGD;Acc:S000005224]</Hit_def>
  <Hit_accession>YNL280C</Hit_accession>
  <Hit_len>438</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>149.058</Hsp_bit-score>
      <Hsp_score>375</Hsp_score>
      <Hsp_evalue>8.08011e-40</Hsp_evalue>
      <Hsp_query-from>356</Hsp_query-from>
      <Hsp_query-to>1210</Hsp_query-to>
      <Hsp_hit-from>68</Hsp_hit-from>
      <Hsp_hit-to>438</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>125</Hsp_identity>
      <Hsp_positive>168</Hsp_positive>
      <Hsp_gaps>100</Hsp_gaps>
      <Hsp_align-len>378</Hsp_align-len>
      <Hsp_qseq>GLAQLWDVRAFGICVAWILFQALLYTLPIGYVAEGLPLKNGKKLKYKINAFQAFIITLATLGLAVYYGL------DLSYIHDRLLQXXXXXXXXXXXXXTYLYARSLT----------KPESELSTAGNSGFFSYDFFMGHELNPRIGSFDFKYFCELRPGLIGW----------------------------------------ECILTTMDIVHDGFGFMLVCGDLAWVPFVYSLQANYLVSHPRSISYASAALICVVKGVGYVIFRGANSQKNAFRRNPNDHAVS-------------------------------------RFSHXXXXXXXXXXXXXXXHREARDANQCGKKYGAAWEEYCNRVKYRIFPYIY</Hsp_qseq>
      <Hsp_hseq>GNRELWTVY----CLWYGILAVLDVILP-GRVMKGVQLRDGSKLSYKINGIA--MSTTLVLVLAIRWKLTDGQLPELQYLYENHVSLCIISILFSFFLATYCYVASFIPLIFKKNGNGKREKILALGGNSGNIIYDWFIGRELNPRLGPLDIKMFSELRPGMLLWLLINLSCLHHHYLKTGKINDALVLVNFLQGFYIFDGVLNEEGVLTMMDITTDGFGFMLAFGDLSLVPFTYSLQARYLSVSPVELGWVKVVGILAIMFLGFHIFHSANKQKSEFRQGKLENLKSIQTKRGTKLLCDGWWAKSQHINYFGDWLISLSWCLATWFQTPLTYYYSLYFATLLLHRQQRDEHKCRLKYGENWEEYERKVPYKIIPYVY</Hsp_hseq>
      <Hsp_midline>G  +LW V     C+ + +   L   LP G V +G+ L++G KL YKIN     + T   L LA+ + L      +L Y+++  +     +IL S  L+TY Y  S            K E  L+  GNSG   YD+F+G ELNPR+G  D K F ELRPG++ W                                        E +LT MDI  DGFGFML  GDL+ VPF YSLQA YL   P  + +     I  +  +G+ IF  AN QK+ FR+   ++  S                                      F   L Y+Y LYF  LL+HR+ RD ++C  KYG  WEEY  +V Y+I PY+Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YGL012W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:472855:474276:1 gene:YGL012W transcript:YGL012W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ERG4 description:C-24(28) sterol reductase; catalyzes the final step in ergosterol biosynthesis; mutants are viable, but lack ergosterol [Source:SGD;Acc:S000002980]</Hit_def>
  <Hit_accession>YGL012W</Hit_accession>
  <Hit_len>473</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>84.3445</Hsp_bit-score>
      <Hsp_score>207</Hsp_score>
      <Hsp_evalue>8.20369e-18</Hsp_evalue>
      <Hsp_query-from>173</Hsp_query-from>
      <Hsp_query-to>1054</Hsp_query-to>
      <Hsp_hit-from>3</Hsp_hit-from>
      <Hsp_hit-to>367</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>101</Hsp_identity>
      <Hsp_positive>141</Hsp_positive>
      <Hsp_gaps>87</Hsp_gaps>
      <Hsp_align-len>373</Hsp_align-len>
      <Hsp_qseq>KDRDHQRDTMGKEKAGVK----------------ELEFGGPLGTVALLALMPCTILYLVLLCGSEDGGVLSVPAP----------------PGGLAQLWDVRAFGICVAWILFQALLYTLPIGYVAEGLPLKN--GKKLKYKINAFQAFIITLATLGLAVYYG--LDLSYIHDRLLQXXXXXXXXXXXXXTYLYARSLTKPESELSTAGNSGFFSYDFFMGHELNPRIGSFDFKYFCELR-------------------------PGL---------------IGWECILTTMDIVHDGFGFMLVCGDLAWVPFVYSLQANYLVSHPRSISYASAAL---ICVVKGVGYVIFRGANSQKNAFRRNPNDHAVSR</Hsp_qseq>
      <Hsp_hseq>KDNSEKLQVQGEEKKSKQPVNFLPQGKWLKPNEIEYEFGGTTGVIGMLIGFPL-LMYYMWICAEFYHGKVALPKAGESWMHFIKHLYQLVLENGIPEKYDWTIF--LTFWVFQIIFYYTLP-GIWTKGQPLSHLKGKQLPYFCNAMWTLYVT-TTLVLVLHFTNLFRLYVIIDRFGRIMTCAIISGFAFSIILYLWTLFISHDYHRMTGNH---LYDFFMGAPLNPRWGILDLKMFFEVRLPWFTLYFITLGACLKQWETYGYVTPQLGVVMLAHWLYANACAKGEELIVPTWDMAYEKFGFMLIFWNIAGVPYTYCHCTLYLYYHDPSEYHWSTLYNVSLYVVLLCAYYFFDTANAQKNAFRKQMSGDKTGR</Hsp_hseq>
      <Hsp_midline>KD   +    G+EK   +                E EFGG  G + +L   P  ++Y + +C     G +++P                    G+ + +D   F     W+      YTLP G   +G PL +  GK+L Y  NA     +T  TL L +++     L  I DR  +    AI+     S  LY  +L          GN     YDFFMG  LNPR G  D K F E+R                         P L                G E I+ T D+ ++ FGFML+  ++A VP+ Y     YL  H  S  + S      + VV    Y  F  AN+QKNAFR+  +     R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1129811098</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

