<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0057498-RA transcript Note:&quot;Similar to Prex2 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (Mus musculus)&quot; offset:0 AED:0.73 eAED:0.74 QI:0|0|0|0.42|1|1|7|0|237</BlastOutput_query-def>
  <BlastOutput_query-len>714</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057498-RA transcript Note:&quot;Similar to Prex2 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (Mus musculus)&quot; offset:0 AED:0.73 eAED:0.74 QI:0|0|0|0.42|1|1|7|0|237</Iteration_query-def>
  <Iteration_query-len>714</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>87</Statistics_hsp-len>
      <Statistics_eff-space>353319917</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057499-RA transcript Note:&quot;Similar to Prex2 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (Mus musculus)&quot; offset:0 AED:0.48 eAED:0.49 QI:0|0|0|0.75|0.66|0.75|4|0|124</Iteration_query-def>
  <Iteration_query-len>375</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YJR138W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:684567:689321:1 gene:YJR138W transcript:YJR138W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IML1 description:GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex; SEACIT (Iml1p-Npr2p-Npr3p) is a subcomplex of the SEA complex, a coatomer-related complex that associates dynamically with the vacuole; Iml1p functions in the SEACIT complex as a GAP for the Rag family GTPase Gtr1p (EGOC subunit), resulting in the inhibition of TORC1 signaling in response to amino acid deprivation; the Iml1p/SEACIT complex is required for non-nitrogen-starvation (NNS)-induced autophagy [Source:SGD;Acc:S000003899]</Hit_def>
  <Hit_accession>YJR138W</Hit_accession>
  <Hit_len>1584</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>42.743</Hsp_bit-score>
      <Hsp_score>99</Hsp_score>
      <Hsp_evalue>4.43598e-06</Hsp_evalue>
      <Hsp_query-from>169</Hsp_query-from>
      <Hsp_query-to>336</Hsp_query-to>
      <Hsp_hit-from>1206</Hsp_hit-from>
      <Hsp_hit-to>1262</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>34</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>57</Hsp_align-len>
      <Hsp_qseq>DRKKKFATVPKCFLGSEFVSWL-KDVGEISKREEGINLGQALLENGIIHHGLIRLPF</Hsp_qseq>
      <Hsp_hseq>NRKWHWKKHEKCFVGSEMVNWLIRNFSDIDTREDAIKYGQKVMKEGLFVHVLNKHNF</Hsp_hseq>
      <Hsp_midline>+RK  +    KCF+GSE V+WL ++  +I  RE+ I  GQ +++ G+  H L +  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>79</Statistics_hsp-len>
      <Statistics_eff-space>110062682</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057500-RA transcript Note:&quot;Similar to Prex2 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (Mus musculus)&quot; offset:0 AED:0.70 eAED:0.71 QI:0|0|0|0.4|0.5|0.6|5|0|219</Iteration_query-def>
  <Iteration_query-len>660</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>86</Statistics_hsp-len>
      <Statistics_eff-space>314426578</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0030231-RA transcript Note:&quot;Similar to PREX2 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (Homo sapiens)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.5|0.38|13|136|583</Iteration_query-def>
  <Iteration_query-len>1888</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1215488911</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057501-RA transcript Note:&quot;Similar to Prex2 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (Mus musculus)&quot; offset:0 AED:0.19 eAED:0.19 QI:0|0.6|0.5|0.66|0.8|0.66|6|503|185</Iteration_query-def>
  <Iteration_query-len>1061</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>606128354</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057503-RA transcript Note:&quot;Similar to EIPR1 EARP and GARP complex-interacting protein 1 (Homo sapiens)&quot; offset:158 AED:0.19 eAED:0.19 QI:158|0.83|1|1|0.5|0.42|7|3635|311</Iteration_query-def>
  <Iteration_query-len>4729</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3291075291</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0040861-RA transcript Note:&quot;Similar to otof Otoferlin (Danio rerio)&quot; offset:275 AED:1.00 eAED:1.00 QI:275|0|0|0|0.2|0.33|6|0|164</Iteration_query-def>
  <Iteration_query-len>770</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>88</Statistics_hsp-len>
      <Statistics_eff-space>391988856</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0030362-RA transcript Note:&quot;Similar to otof Otoferlin (Danio rerio)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.60|0.66|24|1252|674</Iteration_query-def>
  <Iteration_query-len>3277</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2236034464</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057497-RA transcript Note:&quot;Similar to Stk35 Serine/threonine-protein kinase 35 (Mus musculus)&quot; offset:247 AED:0.13 eAED:0.13 QI:247|1|1|1|0.6|0.5|6|4815|336</Iteration_query-def>
  <Iteration_query-len>6073</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.0333</Hsp_bit-score>
      <Hsp_score>201</Hsp_score>
      <Hsp_evalue>5.30775e-16</Hsp_evalue>
      <Hsp_query-from>266</Hsp_query-from>
      <Hsp_query-to>1015</Hsp_query-to>
      <Hsp_hit-from>55</Hsp_hit-from>
      <Hsp_hit-to>254</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>58</Hsp_gaps>
      <Hsp_align-len>254</Hsp_align-len>
      <Hsp_qseq>YELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQP-DHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEGHFTA--KADIFALGIIVWAML-ERITFTD</Hsp_qseq>
      <Hsp_hseq>YQIVKTLGEGSFGKVKLAYHTTTGQKVALKII---------------------------------NKKVLAKSDMQGRI-----EREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLN---VKIADFGLSNI-------MTDGN-----FLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDD</Hsp_hseq>
      <Hsp_midline>Y++++ LG GSFG V  A    TG + A+K I                                 ++ VL  +    R+     ER  +YLRL+      +      +   + +V+EY  G ++  Y++ R          F  Q+  AV + HR+ IVHRDLKP+N+L+ E+     +K+ADFGLS I       ++ G      +L  +CGS  Y APEV  G   A  + D+++ G+I++ ML  R+ F D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.8777</Hsp_bit-score>
      <Hsp_score>198</Hsp_score>
      <Hsp_evalue>5.95197e-16</Hsp_evalue>
      <Hsp_query-from>266</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>47</Hsp_hit-from>
      <Hsp_hit-to>243</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>52</Hsp_gaps>
      <Hsp_align-len>246</Hsp_align-len>
      <Hsp_qseq>YELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLN-TSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVW--EGHFTAKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>YIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSF---------------KDWFESKDKF----------------------YIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGE-----------EDLIYKAAGSLGYVAPEVLTQDGH-GKPCDIWSIGVITYTLL</Hsp_hseq>
      <Hsp_midline>Y   R LG GSFGVV +A    T    A+K +   + +   + LQ L+   S+     H N+V F               +D +E  + +                      ++V +   GG++   +LSR     ++     +Q+  AV ++H  ++VHRDLKP+N+L  + S    L +ADFG++K   G+              +  A GS  Y+APEV   +GH     DI+++G+I + +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.2629</Hsp_bit-score>
      <Hsp_score>199</Hsp_score>
      <Hsp_evalue>1.35753e-15</Hsp_evalue>
      <Hsp_query-from>587</Hsp_query-from>
      <Hsp_query-to>1075</Hsp_query-to>
      <Hsp_hit-from>185</Hsp_hit-from>
      <Hsp_hit-to>335</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>NSYYLWLVMEYCDGGDMNGYLLS------RQPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEG--HFTAKADIFALGIIVWAMLE-RITFTDAESKRKLLGSYVRQGRRIVP</Hsp_qseq>
      <Hsp_hseq>NKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYF-----KQIVEGVSYCHSFNICHRDLKPENLLLDKKNRR--IKIADFGMAAL-----------ELPNK-LLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLK--VQSGKYQMP</Hsp_hseq>
      <Hsp_midline>N   L+LV+EY DGG++  YL+S      R+  H+       Q+   V++ H  +I HRDLKP+N+L+ + + R  +K+ADFG++ +           E  N+  L  +CGS  Y +PE+  G  +    +D+++ GI+++A+L   + F D   K+ LL   V+ G+  +P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.7962</Hsp_bit-score>
      <Hsp_score>190</Hsp_score>
      <Hsp_evalue>1.61232e-15</Hsp_evalue>
      <Hsp_query-from>248</Hsp_query-from>
      <Hsp_query-to>1207</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>267</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>85</Hsp_identity>
      <Hsp_positive>142</Hsp_positive>
      <Hsp_gaps>83</Hsp_gaps>
      <Hsp_align-len>335</Hsp_align-len>
      <Hsp_qseq>MAAEPKYELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESV-ELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHW-------LNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEGH--FTAKADIFALGIIVWAMLE-RITF--TDAESKRKLLGSYV-RQGRRIVPVGEALLE-NPRTELHIPRRRHSPMSTAMAVLVREMLSPHPQERPD</Hsp_qseq>
      <Hsp_hseq>MSSSSQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELK----HENIVRLYDVIHTENK-------------------------------------LTLVFEFMDN-DLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLI---NKRGQLKLGDFGLARAF---------GIPVNT--FSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPKYNPNIQQRPPRD------------LRQVLQPHTKEPLD</Hsp_hseq>
      <Hsp_midline>M++  +++ L +LG G++  VY+ + + TG   A+K ++  S E      ++E+  +K ++    H N+VR  + +   N                                      L LV E+ D  D+  Y+ SR   +        L   F  QL + +AF H N I+HRDLKP N+L+   + R  LK+ DFGL++ F         G  VN    S    + +Y AP+V  G   ++   DI++ G I+  M+  +  F  T+ E + KL+   +      + P    L + NP  +   PR             +R++L PH +E  D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.7221</Hsp_bit-score>
      <Hsp_score>195</Hsp_score>
      <Hsp_evalue>4.21802e-15</Hsp_evalue>
      <Hsp_query-from>266</Hsp_query-from>
      <Hsp_query-to>1063</Hsp_query-to>
      <Hsp_hit-from>120</Hsp_hit-from>
      <Hsp_hit-to>360</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>130</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>272</Hsp_align-len>
      <Hsp_qseq>YELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGN-SYYLWLVMEYCDGGDMNGYLLSRQP--DHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEGH-FTA-KADIFALGIIVWAML-ERITFTDAESKRKLLGSYVRQGR</Hsp_qseq>
      <Hsp_hseq>WEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAF-------LHKEQMLPPPKNEQDVLERQKKLEKEISRDKRTIR------EASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIREHQAR-KFARGIASALIYLHANNIVHRDLKIENIMISDSSE---IKIIDFGLSNIYDSRKQ------------LHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENS--SVLHEKIKQGK</Hsp_hseq>
      <Hsp_midline>+E +  +G GS G V  A  R T    AVK +   +          L   + + PP+   +V+   + + +   R  R  R      EA L  +       R F     S + +++ EY  GG +  Y++      +H     FA  ++ A+ +LH N+IVHRDLK +NI+++++S    +K+ DFGLS I+  + Q            L   CGS ++ APE+ + + +T  + D+++ G++++ ++  ++ F D  S   +L   ++QG+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.9518</Hsp_bit-score>
      <Hsp_score>193</Hsp_score>
      <Hsp_evalue>6.69403e-15</Hsp_evalue>
      <Hsp_query-from>284</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>1272</Hsp_hit-from>
      <Hsp_hit-to>1494</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>66</Hsp_gaps>
      <Hsp_align-len>263</Hsp_align-len>
      <Hsp_qseq>LGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLL-SRQPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESV---------------------NRAWLSPACGSSFYMAPEVWEGHFT----AKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>IGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNHPNIVSY---------YGVEVHRDKVN----------------------------IFMEYCEGGSLAALLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNG---VIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMI</Hsp_hseq>
      <Hsp_midline>+G G+FG VY AV    G   AVK I     +S++     +    SV     H N+V +             + RD                               + MEYC+GG +   L   R  D  +   + +QL   +A+LH + IVHRD+KP+NIL+  N    V+K  DFG +K  A  G  L+S   +                     N   L    G+  YMAPE   G  T       D+++LG +V  M+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.411</Hsp_bit-score>
      <Hsp_score>189</Hsp_score>
      <Hsp_evalue>1.68532e-14</Hsp_evalue>
      <Hsp_query-from>263</Hsp_query-from>
      <Hsp_query-to>997</Hsp_query-to>
      <Hsp_hit-from>619</Hsp_hit-from>
      <Hsp_hit-to>809</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>66</Hsp_gaps>
      <Hsp_align-len>251</Hsp_align-len>
      <Hsp_qseq>KYELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLNT-----SFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWE-GHFTAKADIFALGIIVWAMLE</Hsp_qseq>
      <Hsp_hseq>KYANLVKIGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKELIINEILVMKGSK----HPNIVNFIDSYV---------------------------LKGD----------LWVIMEYMEGGSLTDVVT-----HCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGD---IKLTDFG----FCAQINEL----NLKRTTM---VGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIE</Hsp_hseq>
      <Hsp_midline>KY  L ++G+G+ G VY A   GT    A+K++        EL + E+  +K  +    H N+V F +  +                           LKG+          LW++MEY +GG +   +      H + T     +   +    + FLH   ++HRD+K DNIL++       +K+ DFG    F  Q   L    ++ R  +    G+ ++MAPEV     +  K DI++LGI++  M+E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.411</Hsp_bit-score>
      <Hsp_score>189</Hsp_score>
      <Hsp_evalue>1.9625e-14</Hsp_evalue>
      <Hsp_query-from>590</Hsp_query-from>
      <Hsp_query-to>1075</Hsp_query-to>
      <Hsp_hit-from>195</Hsp_hit-from>
      <Hsp_hit-to>343</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>168</Hsp_align-len>
      <Hsp_qseq>SYYLWLVMEYCDGGDMNGYLL---SRQPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEGH-FTA-KADIFALGIIVWAML-ERITFTDAESKRKLLGSYVRQGRRIVP</Hsp_qseq>
      <Hsp_hseq>SNHFYMLFEYVSGGQLLDYIIQHGSLKEHHA--RKFARGIASALQYLHANNIVHRDLKIENIMIS-SSGE--IKIIDFGLSNIFDY------------RKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENS--SILHEKIKKGKVDYP</Hsp_hseq>
      <Hsp_midline>S + +++ EY  GG +  Y++   S +  H     FA  ++ A+ +LH N+IVHRDLK +NI+++ +SG   +K+ DFGLS IF              R  L   CGS ++ APE+ +   +T  + DI++ GI+++ ++  ++ F D  S   +L   +++G+   P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.0258</Hsp_bit-score>
      <Hsp_score>188</Hsp_score>
      <Hsp_evalue>2.2408e-14</Hsp_evalue>
      <Hsp_query-from>284</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>204</Hsp_hit-from>
      <Hsp_hit-to>402</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>72</Hsp_gaps>
      <Hsp_align-len>254</Hsp_align-len>
      <Hsp_qseq>LGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGL-QELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQP-DHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVL-KVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEG--------------HFTAKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>VGQGAFATVKKAIERTTGKTFAVKIISKRKVIGNMDGVTRELEVLQKLNHPR----IVRL---------------KGFYEDTESY----------------------YMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDD--PVLVKITDFGLAKV---QGNG---------SFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVIL</Hsp_hseq>
      <Hsp_midline>+G+G+F  V +A+ R TG   AVK I          G+ +EL  L+ +  PR    +VR                +  YE  E+Y                      ++VME+  GGD+  ++ +            + Q+  A+ ++H   I HRDLKPDNIL+ ++   PVL K+ DFGL+K+   QG G         +++   CG+  Y+APEV  G               +++  D++++G +V+ +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.8702</Hsp_bit-score>
      <Hsp_score>185</Hsp_score>
      <Hsp_evalue>3.46333e-14</Hsp_evalue>
      <Hsp_query-from>536</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>79</Hsp_hit-from>
      <Hsp_hit-to>216</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>161</Hsp_align-len>
      <Hsp_qseq>LRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLNTSFAM----QLSRAVAFLHRNS-IVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVW---EGHFTAKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>LRLIDCNVSKE---------YMWIILEMADGGDLFDKI---EPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENILLDKNGN---LKLADFGLASQFRRKDGTLRV--SMDQR------GSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLL</Hsp_hseq>
      <Hsp_midline>LRL++ ++  E         Y+W+++E  DGGD+   +   +PD  +++  A     QL  A+ +LH    + HRD+KP+NIL+ +N     LK+ADFGL+  F  +   L    S+++       GS  YMAPEV    EG++  + DI+++GI+++ +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.0998</Hsp_bit-score>
      <Hsp_score>183</Hsp_score>
      <Hsp_evalue>5.77879e-14</Hsp_evalue>
      <Hsp_query-from>239</Hsp_query-from>
      <Hsp_query-to>1066</Hsp_query-to>
      <Hsp_hit-from>307</Hsp_hit-from>
      <Hsp_hit-to>547</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>84</Hsp_identity>
      <Hsp_positive>125</Hsp_positive>
      <Hsp_gaps>67</Hsp_gaps>
      <Hsp_align-len>292</Hsp_align-len>
      <Hsp_qseq>DKAMAAEPKYELLRE-LGRGSFGVVYEAVVRGTGARR--------AVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLNTS-FAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFA---GQGQGLSSGESVNRAWLSPACGSSFYMAPE--VWEGHFTAKADIFALGIIVWAM-LERITFTDAESKRKLLGSYVRQGRR</Hsp_qseq>
      <Hsp_hseq>DRQCFAE-KYGRCQEVLGKGAFGVVRICQKKNVSSQDGNKSEKLYAVKEFKRRTSESAEKYSKRLTSEFCISSSLHHTNIV-------------------------TTLDLFQDA-KGEYC----------EVMEYCAGGDLFTLVVAAGKLEYMEADCFFKQLIRGVVYMHEMGVCHRDLKPENLLLTHDG---VLKITDFGNSECFKMAWEKNIHLSGG----------VCGSSPYIAPEEYIKEEFDPRPVDIWACGVIYMAMRTGRQLWSSAEKDDPFYMNYLK-GRK</Hsp_hseq>
      <Hsp_midline>D+   AE KY   +E LG+G+FGVV     +   ++         AVK  +  + ES E   + L +   +     H N+V                           L L + + KGE C           VMEYC GGD+   +++     ++    F  QL R V ++H   + HRDLKP+N+L+  +    VLK+ DFG S+ F     +   LS G           CGSS Y+APE  + E       DI+A G+I  AM   R  ++ AE       +Y++ GR+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.485</Hsp_bit-score>
      <Hsp_score>184</Hsp_score>
      <Hsp_evalue>6.22085e-14</Hsp_evalue>
      <Hsp_query-from>248</Hsp_query-from>
      <Hsp_query-to>991</Hsp_query-to>
      <Hsp_hit-from>18</Hsp_hit-from>
      <Hsp_hit-to>260</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>103</Hsp_gaps>
      <Hsp_align-len>297</Hsp_align-len>
      <Hsp_qseq>MAAEPKYELLRELGRGSFGVVYEAVVRGTGAR----RAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLN--------------------------TSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAEN------------------SGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWE-GHFTAKADIFALGIIVWAM</Hsp_qseq>
      <Hsp_hseq>MASAGNYTAEKEIGKGSFATVYRGHLTSDKSQHVAIKEVSRAKLKNKKLLENLEIEIAILKKIKHPH----IVGLIDC--------ERTSTD-----------------------------FYLIMEYCALGDL-TFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLP------------NTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVVFEM</Hsp_hseq>
      <Hsp_midline>MA+   Y   +E+G+GSF  VY   +    ++    + V R +  + + +E    E+  LK ++ P     +V   +C         R + D                              +L+MEYC  GD+  +LL R+ +   N                           S+  QL+ A+ FL   ++VHRD+KP N+L++                       P+LK+ADFG ++               N +     CGS  YMAPE+     + AKAD++++G +V+ M</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.7146</Hsp_bit-score>
      <Hsp_score>182</Hsp_score>
      <Hsp_evalue>1.10037e-13</Hsp_evalue>
      <Hsp_query-from>572</Hsp_query-from>
      <Hsp_query-to>1204</Hsp_query-to>
      <Hsp_hit-from>147</Hsp_hit-from>
      <Hsp_hit-to>326</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>218</Hsp_align-len>
      <Hsp_qseq>CFGPGNSYYLWLVMEYCDGGDMNGYLLSR----QPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEGHFTA---KADIFALGIIVWAMLERITFTDAESKRKLLGSYVRQGRRIVPVGEALLENPRTELHIPRRRHSPMSTAMAVLVREMLSPHPQERP</Hsp_qseq>
      <Hsp_hseq>CFEDDSNVYILL--EICPNGSLMELLKRRKVLTEPEVRF---FTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYN---LKIGDFGLAAVLANESE---------RKYT--ICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYAL--------------LIGKPPFQARDVNTIYERI---KCRDFSFPRDK--PISDEGKILIRDILSLDPIERP</Hsp_hseq>
      <Hsp_midline>CF   ++ Y+ L  E C  G +   L  R    +P+      F  Q+  A+ ++H   ++HRDLK  NI    N     LK+ DFGL+ + A + +         R +    CG+  Y+APEV  G  +    + DI++LG++++A+              L+G    Q R +  + E +      +   PR +  P+S    +L+R++LS  P ERP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.7886</Hsp_bit-score>
      <Hsp_score>177</Hsp_score>
      <Hsp_evalue>3.14915e-13</Hsp_evalue>
      <Hsp_query-from>542</Hsp_query-from>
      <Hsp_query-to>1009</Hsp_query-to>
      <Hsp_hit-from>289</Hsp_hit-from>
      <Hsp_hit-to>445</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>177</Hsp_align-len>
      <Hsp_qseq>LVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQP--DHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAE-----NSGR--PV------LKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEV-----WEGHFTAKADIFALGIIVWAMLE-RITF</Hsp_qseq>
      <Hsp_hseq>LCDLIIKTPRALPPCD-----MIMSYCPAGDLLAAVMARNGRLEAWLIQRIFTEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLCKKIE------------NNEMCTARCGSEDYVSPEILMGVPYDGHL---SDTWALGVILYSLFEDRLPF</Hsp_hseq>
      <Hsp_midline>L +  +K  R   P +     ++M YC  GD+   +++R    + WL      ++  AV +LH NSI+HRDLK +NIL+       NS R  P+      +++ADFGL K               N    +  CGS  Y++PE+     ++GH    +D +ALG+I++++ E R+ F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>3.77814e-13</Hsp_evalue>
      <Hsp_query-from>263</Hsp_query-from>
      <Hsp_query-to>1000</Hsp_query-to>
      <Hsp_hit-from>24</Hsp_hit-from>
      <Hsp_hit-to>214</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>63</Hsp_gaps>
      <Hsp_align-len>250</Hsp_align-len>
      <Hsp_qseq>KYELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQP---DHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEGH-FTAKADIFALGIIVWAMLER</Hsp_qseq>
      <Hsp_hseq>QYHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNL----NHNNIVKY----------------------HGFIR---------------KSYELYILLEYCANGSLRR-LISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILL---SADNTVKLADFGVSTI-------------VNSSALTLA-GTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTK</Hsp_hseq>
      <Hsp_midline>+Y L + +GRGS+GVVY+A+ + T    A+K +   + E +   + E+  LK++     H+N+V++                        ++R                SY L++++EYC  G +   L+SR         + ++  Q    + +LH   ++HRD+K  NIL+   S    +K+ADFG+S I             VN + L+ A G+  +MAPE+      +  +DI++LG  V  ML +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.4034</Hsp_bit-score>
      <Hsp_score>176</Hsp_score>
      <Hsp_evalue>4.58896e-13</Hsp_evalue>
      <Hsp_query-from>284</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>421</Hsp_hit-from>
      <Hsp_hit-to>651</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>119</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>259</Hsp_align-len>
      <Hsp_qseq>LGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGL--------------------QELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQP-DHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVW-EGHFTAKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>IGSGSFGSVYLGMNAHTGELMAVKQVEI---KNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHH-----ENIVTYYGASQEG------GN---LNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILI---DIKGCVKITDFGISKKLSPLNKKQNK-----RASLQ---GSVFWMSPEVVKQTATTAKADIWSTGCVVIEMF</Hsp_hseq>
      <Hsp_midline>+G GSFG VY  +   TG   AVK++     ++  +G+                    +++  + +V  P+ + N+ R     LQH     +         E  +     S +G      GN   L + +EY  GG ++  L +  P +  L T+F  Q+   VA+LH+ +I+HRD+K  NIL+     +  +K+ DFG+SK  +   +  +      RA L    GS F+M+PEV  +   TAKADI++ G +V  M </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>6.32594e-13</Hsp_evalue>
      <Hsp_query-from>266</Hsp_query-from>
      <Hsp_query-to>997</Hsp_query-to>
      <Hsp_hit-from>18</Hsp_hit-from>
      <Hsp_hit-to>212</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>67</Hsp_gaps>
      <Hsp_align-len>253</Hsp_align-len>
      <Hsp_qseq>YELLRELGRGSFGVVYEAVVRGTGARRAVKRIRC-CSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWL---NTSFAM-QLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEV----WEGHFTAKADIFALGIIVWAMLE</Hsp_qseq>
      <Hsp_hseq>YSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYI--------------ATMLED---------------------------VSMWIVMEYCGGGSCSD-LLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEG---MVKLGDFGV------------SGHIRSTLKRDTFVGTPYWMAPEVVCCEVDG-YNEKADIWSLGITTYELLK</Hsp_hseq>
      <Hsp_midline>Y +   +GRG+FG VY+AV R T    A+K +    S E +EL  QE++ L  ++ P   + +              A M  D                             +W+VMEYC GG  +  LL R   + L     SF + +++  + +LH    +HRD+K  NIL+ E     ++K+ DFG+            SG   +        G+ ++MAPEV     +G +  KADI++LGI  + +L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.4034</Hsp_bit-score>
      <Hsp_score>176</Hsp_score>
      <Hsp_evalue>6.96775e-13</Hsp_evalue>
      <Hsp_query-from>599</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>784</Hsp_hit-from>
      <Hsp_hit-to>919</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>145</Hsp_align-len>
      <Hsp_qseq>LWLVMEYCDGGDMNGYL----LSRQPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSK-------IFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWE--GHFTAKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>LFIQMEYCENRTLYDLIHSENLNQQRDEYWR--LFRQILEALSYIHSQGIIHRDLKPMNIFIDESRN---VKIGDFGLAKNVHRSLDILKLDSQNL-PGSSDN---LTSAIGTAMYVATEVLDGTGHYNEKIDMYSLGIIFFEMI</Hsp_hseq>
      <Hsp_midline>L++ MEYC+   +   +    L++Q D +       Q+  A++++H   I+HRDLKP NI + E+     +K+ DFGL+K       I     Q L  G S N   L+ A G++ Y+A EV +  GH+  K D+++LGII + M+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>8.2154e-13</Hsp_evalue>
      <Hsp_query-from>599</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>177</Hsp_hit-from>
      <Hsp_hit-to>295</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>134</Hsp_align-len>
      <Hsp_qseq>LWLVMEYCDGGDMNGYLLSRQP-DHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEG-HFTAKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>VYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNN---VIKLTDFGWSIINPPENRRKT------------VCGTIDYLSPEMVESREYDHTIDAWALGVLAFELL</Hsp_hseq>
      <Hsp_midline>++L+MEY   G+M   L    P +  L + +  Q++ A+ ++H+ +I+HRD+KP+NIL+  N+   V+K+ DFG S I   + +  +             CG+  Y++PE+ E   +    D +ALG++ + +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>8.34238e-13</Hsp_evalue>
      <Hsp_query-from>599</Hsp_query-from>
      <Hsp_query-to>1090</Hsp_query-to>
      <Hsp_hit-from>106</Hsp_hit-from>
      <Hsp_hit-to>258</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>169</Hsp_align-len>
      <Hsp_qseq>LWLVMEYCDGGDMNGYLLSRQP--DHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEG--HFTAKADIFALGIIVWAMLE-RITFTDAESKRKLLGSYVRQGRRIVPVGEAL</Hsp_qseq>
      <Hsp_hseq>LYLVLEYAEKGELFNLLVERGPLPEHEA-IRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYN---IKIADFGMA---ALETEG---------KLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEI</Hsp_hseq>
      <Hsp_midline>L+LV+EY + G++   L+ R P  +H     F  Q+   V++ H   IVHRDLKP+N+L+        +K+ADFG++   A + +G           L  +CGS  Y APE+  G  +    +D+++ G+I++A+L  R+ F + +   + L   V++G   +P  + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>8.38292e-13</Hsp_evalue>
      <Hsp_query-from>599</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>253</Hsp_hit-from>
      <Hsp_hit-to>383</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>134</Hsp_align-len>
      <Hsp_qseq>LWLVMEYCDGGDMNGYLLSR-QPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEGHFTA-KADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>LYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILL---DGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMI</Hsp_hseq>
      <Hsp_midline>L+ ++EY   GD    +      D      +A Q+  A+ +LH N I+HRD+KP+NIL+    G   +K+ DFG +K+       +S  E           G++ Y++PE+    FT  + DI+A G I++ M+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.8626</Hsp_bit-score>
      <Hsp_score>172</Hsp_score>
      <Hsp_evalue>8.62599e-13</Hsp_evalue>
      <Hsp_query-from>263</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>36</Hsp_hit-from>
      <Hsp_hit-to>233</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>52</Hsp_gaps>
      <Hsp_align-len>247</Hsp_align-len>
      <Hsp_qseq>KYELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSR-QPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVW--EGHFTAKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>KYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAF---------------KDWFESKDKF----------------------YIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAK-------RLKSDEEL----LYKPAGSLGYVAPEVLTQDGH-GKPCDIWSIGVITYTLL</Hsp_hseq>
      <Hsp_midline>KY   + LG G+FGVV +A    TG   AVK +   + +  ++ L+ L+    +     H N+V F               +D +E  + +                      +++ +   GG++   +L + +          +++  AV ++H  +IVHRDLKP+N+L  + S    L VADFG++K        L S E +    L    GS  Y+APEV   +GH     DI+++G+I + +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>9.35332e-13</Hsp_evalue>
      <Hsp_query-from>284</Hsp_query-from>
      <Hsp_query-to>991</Hsp_query-to>
      <Hsp_hit-from>29</Hsp_hit-from>
      <Hsp_hit-to>213</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>67</Hsp_gaps>
      <Hsp_align-len>244</Hsp_align-len>
      <Hsp_qseq>LGRGSFGVVYEAVVRGTGARRAVKRIRCCSP----ESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWL--SPACGSSFYMAPEV-WEG-HFTAKADIFALGIIVWAM</Hsp_qseq>
      <Hsp_hseq>IGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQIS------NITRY---------------------YGSYLK--DTSL--------------WIIMEHCAGGSLRSLLRPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLIT-NEGN--VKLCDFGV----AAQ---------VNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEI</Hsp_hseq>
      <Hsp_midline>+GRG FGVVY+     TG   A+K +   S     E V+  +Q L +LK +       N+ R+                       +YL+  +TSL              W++ME+C GG +   L   + D         +L  A+  +H+++++HRD+K  N+L+  N G   +K+ DFG+    A Q         VN+  L      G+ ++MAPEV  EG ++  K DI++LGI  + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>1.05794e-12</Hsp_evalue>
      <Hsp_query-from>263</Hsp_query-from>
      <Hsp_query-to>1015</Hsp_query-to>
      <Hsp_hit-from>443</Hsp_hit-from>
      <Hsp_hit-to>654</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>55</Hsp_gaps>
      <Hsp_align-len>259</Hsp_align-len>
      <Hsp_qseq>KYELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLL------SRQPDHWLNTSFAMQLSRAVAFLHRN-SIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVW-EGHFTAKADIFALGIIVWAMLERITFTD</Hsp_qseq>
      <Hsp_hseq>KFTNVHSIGKGQFSTVYQVTFAQTNKKYAIKAIKPNKYNSLKRILLEIKILNEVT------NQITMDQ------------------EGKEYIIDYISSWKFQ------NSYYI--MTELCENGNLDGFLQEQVIAKKKRLEDWRIWKIIVELSLALRFIHDSCHIVHLDLKPANVMITFEGN---LKLGDFGMATHLPLEDKSFENE------------GDREYIAPEIISDCTYDYKADIFSLGLMIVEIAANVVLPD</Hsp_hseq>
      <Hsp_midline>K+  +  +G+G F  VY+     T  + A+K I+     S++  L E+  L  V       N +  D+                   G+ Y+    +S K +      NSYY+  + E C+ G+++G+L        ++ + W      ++LS A+ F+H +  IVH DLKP N+++        LK+ DFG++     + +   +             G   Y+APE+  +  +  KADIF+LG+++  +   +   D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>1.09188e-12</Hsp_evalue>
      <Hsp_query-from>284</Hsp_query-from>
      <Hsp_query-to>991</Hsp_query-to>
      <Hsp_hit-from>1040</Hsp_hit-from>
      <Hsp_hit-to>1245</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>246</Hsp_align-len>
      <Hsp_qseq>LGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYL-LSRQPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVN-----RAWLSPACGSSFYMAPEVWEGHFT----AKADIFALGIIVWAM</Hsp_qseq>
      <Hsp_hseq>IGGGTFGQVYSAINLENGEILAVKEIKIHDTTTMKKIFPLIKEEMTVLEMLNHPNIVQY---------YGVEVHRDKVN----------------------------IFMEYCEGGSLASLLDHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDFNG---IIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEM</Hsp_hseq>
      <Hsp_midline>+G G+FG VY A+    G   AVK I+     +++     +    +V     H N+V++             + RD                               + MEYC+GG +   L   R  D  +   +  +L   +A+LH++ +VHRD+KP+NIL+  N    ++K  DFG ++   G         +V         L+   G+  YMAPE   G          D++ALG +V  M</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>1.48529e-12</Hsp_evalue>
      <Hsp_query-from>266</Hsp_query-from>
      <Hsp_query-to>1102</Hsp_query-to>
      <Hsp_hit-from>41</Hsp_hit-from>
      <Hsp_hit-to>272</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>129</Hsp_positive>
      <Hsp_gaps>75</Hsp_gaps>
      <Hsp_align-len>293</Hsp_align-len>
      <Hsp_qseq>YELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLNTS--FAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWE--GHFTAKADIFALGIIVWAMLE-RITFTD---AESKRKLLGSYVRQGRRIVP------VGEALLENP</Hsp_qseq>
      <Hsp_hseq>YKILKQIGEGSFGKVYLALHRPTHRKVCLKTSDKNDP-----------------------NIVRE---VFYHR-------QFDFPYITKLYEVIVTESK------------VWMALEYCPGKELYDHLLSLRRISLLECGELFA-QISGAVYYAHSMHCVHRDLKLENILLDKNGN---AKLTDFGFTR------------ECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDAKVIPDDARDLISRLLAKNP</Hsp_hseq>
      <Hsp_midline>Y++L+++G GSFG VY A+ R T  +  +K      P                       N+VR    V  H        + D+        ++ T  K            +W+ +EYC G ++  +LLS +    L     FA Q+S AV + H    VHRDLK +NIL+ +N      K+ DFG ++            E + +  L   CG++ YMAPE+ E   +   K DI++LG+I++ ++   + F D   A++K K++    +   +++P      +   L +NP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>1.66451e-12</Hsp_evalue>
      <Hsp_query-from>242</Hsp_query-from>
      <Hsp_query-to>1075</Hsp_query-to>
      <Hsp_hit-from>57</Hsp_hit-from>
      <Hsp_hit-to>285</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>126</Hsp_positive>
      <Hsp_gaps>69</Hsp_gaps>
      <Hsp_align-len>288</Hsp_align-len>
      <Hsp_qseq>KAMAAEPKY-----ELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLN---TSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEGH-FTAKADIFALGIIVWAMLERIT-FTDAESKRKLLGSYVRQGRRIVP</Hsp_qseq>
      <Hsp_hseq>KSLVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKK----------QQVVKMKQV-----------------EHTNDERRM-----------LKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGEL--FSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGH---IKITDFGFAK------------EVQTVTWT--LCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTY--EKILQGKVVYP</Hsp_hseq>
      <Hsp_midline>K++ ++ KY     +++R LG GSFG V+       G   A+K ++           Q++  +K V                 +H     RM           L+LVE            ++  +++VM+Y +GG++  + L R+   + N     +A ++  A+ +LH ++I++RDLKP+NIL+  N     +K+ DFG +K            E     W    CG+  Y+APEV     +    D ++LG++++ ML   T F D    +      + QG+ + P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>2.35913e-12</Hsp_evalue>
      <Hsp_query-from>587</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>121</Hsp_hit-from>
      <Hsp_hit-to>246</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>140</Hsp_align-len>
      <Hsp_qseq>NSYYLWLVMEYCDGGDMNGYLLSRQPDHWLNTS-FAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEV---WEGHFTAKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>NSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNEN---LVITDFGFVNEFCSRNELMKT-----------SCGSPCYAAPELVISAEPYEARKADIWSCGVILYAIL</Hsp_hseq>
      <Hsp_midline>NS Y+ +V+EY  GG+   Y+  ++    +N      QL   V ++H   +VHRDLK +N+L+ +N     L + DFG    F  + + + +           +CGS  Y APE+    E +   KADI++ G+I++A+L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>2.53215e-12</Hsp_evalue>
      <Hsp_query-from>266</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>88</Hsp_hit-from>
      <Hsp_hit-to>277</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>61</Hsp_gaps>
      <Hsp_align-len>247</Hsp_align-len>
      <Hsp_qseq>YELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLN---TSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEGH-FTAKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>FQILRTLGTGSFGRVH--LIRSNHNGR-------------------FYALKTLK----KHTIVKLKQ--VEHTNDERRM-----------LSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGEL--FSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGH---IKITDFGFAKYVPDVTYTL--------------CGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEML</Hsp_hseq>
      <Hsp_midline>+++LR LG GSFG V+  ++R     R                    +ALK+++     H +V+  +  ++H     RM           L +V             +S  +++VM+Y +GG++  + L R+   + N     +A ++  A+ +LH   I++RDLKP+NIL+ +N     +K+ DFG +K        L              CG+  Y+APEV     +    D ++ G++++ ML</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YFL029C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:78055:79161:-1 gene:YFL029C transcript:YFL029C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CAK1 description:Cyclin-dependent kinase-activating kinase; required for passage through the cell cycle; phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases [Source:SGD;Acc:S000001865]</Hit_def>
  <Hit_accession>YFL029C</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>4.71888e-12</Hsp_evalue>
      <Hsp_query-from>608</Hsp_query-from>
      <Hsp_query-to>1006</Hsp_query-to>
      <Hsp_hit-from>120</Hsp_hit-from>
      <Hsp_hit-to>242</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>137</Hsp_align-len>
      <Hsp_qseq>VMEYCDGGDMNGYLLSRQPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSG--RPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEG--HFTAKADIFALGIIVWAMLERIT</Hsp_qseq>
      <Hsp_hseq>VQKYTNQLDVNRYSLS----------FFRQMVEGIAFLHENKIIHRDIKPQNIMLTNNTSTVSPKLYIIDFGISYDMANNSQ--TSAEPMDSKVTDISTG--IYKAPEVLFGVKCYDGGVDVWSLLIIISQWFQRET</Hsp_hseq>
      <Hsp_midline>V +Y +  D+N Y LS          F  Q+   +AFLH N I+HRD+KP NI++  N+    P L + DFG+S   A   Q  +S E ++      + G   Y APEV  G   +    D+++L II+    +R T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>5.51002e-12</Hsp_evalue>
      <Hsp_query-from>266</Hsp_query-from>
      <Hsp_query-to>1027</Hsp_query-to>
      <Hsp_hit-from>8</Hsp_hit-from>
      <Hsp_hit-to>217</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>118</Hsp_positive>
      <Hsp_gaps>66</Hsp_gaps>
      <Hsp_align-len>265</Hsp_align-len>
      <Hsp_qseq>YELLRELGRGSFGVVYEAV-VR-GTGARR-AVKRIRCCSPES--VELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLNTS----FAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEG--HFTAKADIFALGIIVWAMLERITFTDAESK</Hsp_qseq>
      <Hsp_hseq>YKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELK----DDNIVRLYDIV--HS----------------------------------DAHKLYLVFEFLDL-DLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGN---LKLGDFGLARAFGVPLRAYT--HEIVTLW---------YRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSE</Hsp_hseq>
      <Hsp_midline>Y+ L ++G G++GVVY+A+ +R G G R  A+K+IR  S +       ++E+  LK ++      N+VR  + V  H+                                  +++ L+LV E+ D  D+  Y+     D  L       F MQL + +A+ H + I+HRDLKP N+L+ ++     LK+ DFGL++ F    +  +    +   W         Y APEV  G   ++   D +++G I   M  R      +S+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>1.13348e-11</Hsp_evalue>
      <Hsp_query-from>260</Hsp_query-from>
      <Hsp_query-to>997</Hsp_query-to>
      <Hsp_hit-from>358</Hsp_hit-from>
      <Hsp_hit-to>577</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>82</Hsp_gaps>
      <Hsp_align-len>274</Hsp_align-len>
      <Hsp_qseq>PKYELLRELGRGSFGVVYEA-----------------VVRGTGARRAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYL----LSRQPDHW--LNTS----FAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPE-VWEGHFTAKADIFALGIIVWAMLE</Hsp_qseq>
      <Hsp_hseq>PYFQLVEKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQPKKQLIMNELLVMNDSR----QENIVNFLEAYI----------IDDEE--------------------------LWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILL---NSQGLVKITDFGFCVELTEK-----------RSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIE</Hsp_hseq>
      <Hsp_midline>P ++L+ + G+G+ G VY +                   R  G R A+K+IR       +L + EL  +   R      N+V F E  +           DD E                          LW++MEY +GG +   L     S   +H   LN +       +  + + FLH   I+HRD+K DNIL+   + + ++K+ DFG       +           R+  +   G+ ++MAPE V +  +  K D+++LGI++  M+E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>1.30161e-11</Hsp_evalue>
      <Hsp_query-from>266</Hsp_query-from>
      <Hsp_query-to>1054</Hsp_query-to>
      <Hsp_hit-from>87</Hsp_hit-from>
      <Hsp_hit-to>300</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>119</Hsp_positive>
      <Hsp_gaps>65</Hsp_gaps>
      <Hsp_align-len>271</Hsp_align-len>
      <Hsp_qseq>YELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLN---TSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEGH-FTAKADIFALGIIVWAMLERIT-FTDAESKR---KLLGSYVR</Hsp_qseq>
      <Hsp_hseq>FQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKK----------EIVVRLKQVE----HTNDERLMLSIVTH---------------PFIIRMWGTFQDAQQIF---------MIMDYIEGGEL--FSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGH---IKITDFGFAKYVPDVTYTL--------------CGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELR</Hsp_hseq>
      <Hsp_midline>+++LR LG GSFG V+    R  G   A+K ++           + +  LK V     H N  R    ++ H                  +R+  T    ++ F         ++M+Y +GG++  + L R+   + N     +A ++  A+ +LH   I++RDLKP+NIL+ +N     +K+ DFG +K        L              CG+  Y+APEV     +    D ++ GI+++ ML   T F D+ + +   K+L + +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>1.40941e-11</Hsp_evalue>
      <Hsp_query-from>239</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>14</Hsp_hit-from>
      <Hsp_hit-to>227</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>54</Hsp_gaps>
      <Hsp_align-len>260</Hsp_align-len>
      <Hsp_qseq>DKAMAAEPKYELLRELGRGSFGVVYEA--VVRGTGARRAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQP---DHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEV---WEGHFTAKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>NQDFSVDKRFQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTL-LCKRSLRELKLLRHFRGHKNIT----CL--------------YDMDIVFYPD-----------GSINGLYLYEELMECD---MHQIIKSGQPLTDAHY--QSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQ---LKICDFGLAR-------GYSENPVENSQFLTEYVATRWYRAPEIMLSYQG-YTKAIDVWSAGCILAEFL</Hsp_hseq>
      <Hsp_midline>++  + + +++L++E+G G++G+V  A           A+K++     +++ L  + L  LK +R  RGH N+     C+              Y+    +              G  N  YL+  +  CD   M+  + S QP    H+   SF  Q+   + ++H   ++HRDLKP N+LV  +     LK+ DFGL++       G S     N  +L+    + +Y APE+   ++G +T   D+++ G I+   L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>1.85419e-11</Hsp_evalue>
      <Hsp_query-from>266</Hsp_query-from>
      <Hsp_query-to>1039</Hsp_query-to>
      <Hsp_hit-from>13</Hsp_hit-from>
      <Hsp_hit-to>233</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>120</Hsp_positive>
      <Hsp_gaps>43</Hsp_gaps>
      <Hsp_align-len>261</Hsp_align-len>
      <Hsp_qseq>YELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVW--EGHFTAKADIFALGIIVWAM-LERITFTDAESKRKLL</Hsp_qseq>
      <Hsp_hseq>FQLKSLLGEGAYGVVCSATHKPTGEIVAIKKI--------EPFDKPLFALRTLREIK-----------ILKHFKHENIITIFNIQRPDSFENFNEV-------------YIIQELMQTDLHRVISTQMLSD--DHI--QYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCD---LKVCDFGLARII-DESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLL</Hsp_hseq>
      <Hsp_midline>++L   LG G++GVV  A  + TG   A+K+I        E   + L+AL+++R  +           +L+H      +   + +R +++    E              Y +  +M+      ++  +LS   DH     F  Q  RAV  LH ++++HRDLKP N+L+  N     LKV DFGL++I   +    +S  +  ++ ++    + +Y APEV      ++   D+++ G I+  + L R  F   + + +LL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>2.05909e-11</Hsp_evalue>
      <Hsp_query-from>599</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>199</Hsp_hit-from>
      <Hsp_hit-to>331</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>139</Hsp_align-len>
      <Hsp_qseq>LWLVMEYCDGGDMNGYLLSRQPDHWLNTS----FAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPA--CGSSFYMAPEVWEGHFT-AKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>LYFLLEYAPHGDFLGLI---KKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKNMK---VKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQML</Hsp_hseq>
      <Hsp_midline>L+ ++EY   GD  G +   +    LN +    +A Q+  AV  LH   I+HRD+KP+NIL+ +N     +K+ DFG +KI   +    + G+     +       G++ Y++PE+   ++T ++ DI+A G I++ ML</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>2.23635e-11</Hsp_evalue>
      <Hsp_query-from>263</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>199</Hsp_hit-from>
      <Hsp_hit-to>415</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>73</Hsp_gaps>
      <Hsp_align-len>267</Hsp_align-len>
      <Hsp_qseq>KYELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGLQ---ELWALKSVRPPRGHHNVVRFDECVLQHNGRA---ARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVA----ENSGRPVL------------KVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEGH-FTAKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>KYLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHP----NIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKT-----CLRQDESKALF-----------------------------KQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAK-FTGEMQ-----------FTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVILYVCL</Hsp_hseq>
      <Hsp_midline>KY L +ELG G + +V EA  + TG + AVK       +  +   Q   E   L  V+ P    N+V   +  ++   ++     +  +  + GE + R+V  +     C     S  L+                              QL   + +LH  +I+HRD+KP+NIL+     EN  +  L            K+ADFGL+K F G+ Q           + +  CG+  Y+APEV     +T+K D+++ G+I++  L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>2.73971e-11</Hsp_evalue>
      <Hsp_query-from>284</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>1181</Hsp_hit-from>
      <Hsp_hit-to>1374</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>65</Hsp_gaps>
      <Hsp_align-len>248</Hsp_align-len>
      <Hsp_qseq>LGRGSFGVVYEAVVRGTGARRAVKRIRCCSPES--------VELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYL-LSRQPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEGH--FTAKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>IGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDL----DHLNIVQ-------------------------YL-----------GFENKNNIY-SLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDG---ICKISDFGISR----KSKDIYSNSDMTMR------GTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMF</Hsp_hseq>
      <Hsp_midline>+G+GSFG VY  +   TG   AVK++      S        VE    E+  LK +     H N+V+                         YL            F   N+ Y  L +EY  GG +   + +  + D  L      Q+ + +A+LH   I+HRD+K DN+L+ ++    + K++DFG+S+    + + + S   +         G+ F+MAPE+ +    ++AK DI++LG IV  M </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>2.75608e-11</Hsp_evalue>
      <Hsp_query-from>266</Hsp_query-from>
      <Hsp_query-to>1120</Hsp_query-to>
      <Hsp_hit-from>21</Hsp_hit-from>
      <Hsp_hit-to>276</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>79</Hsp_identity>
      <Hsp_positive>135</Hsp_positive>
      <Hsp_gaps>71</Hsp_gaps>
      <Hsp_align-len>306</Hsp_align-len>
      <Hsp_qseq>YELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVE--TSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLNTSFAM----QLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEG--HFTAKADIFALGIIVWAMLE-RITFTDAESKRKLLGSYVRQGRRIVP------------VGEALLENPRTELHI</Hsp_qseq>
      <Hsp_hseq>WKLGETLGFGSTGKVQLAQHERTGHRTAVKVIS-----------------KSIFNNNGNHS---NDDSVLPYN----------IEREIVIMKLLSHPNVLSLYDVWETNNN--LYLILEYAEKGELFNLLVDHGP---LPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYN---IKIADFGMAAL------------QTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKI</Hsp_hseq>
      <Hsp_midline>++L   LG GS G V  A    TG R AVK I                  KS+    G+H+    D+ VL +N           ER    ++L+     L     +   N+  L+L++EY + G++   L+   P   L    A+    Q+   +++ H   IVHRDLKP+N+L+        +K+ADFG++ +              +   L  +CGS  Y APE+  G  +    +D+++ G+I++A+L  R+ F +     + L   V++G+  +P            +G+ L+ +PR  + I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>2.86813e-11</Hsp_evalue>
      <Hsp_query-from>248</Hsp_query-from>
      <Hsp_query-to>1009</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>204</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>60</Hsp_gaps>
      <Hsp_align-len>259</Hsp_align-len>
      <Hsp_qseq>MAAEPKYELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCS-PESVEL-GLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRL-VETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEG--HFTAKADIFALGIIVWAMLERITF</Hsp_qseq>
      <Hsp_hseq>MKVNMEYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQ----HPNVIELIDIF---------MAYDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTL----------------------------RGVYHCHRNFILHRDLKPNNLLFSPDGQ---IKVADFGLARAIPAPHEILTSN-----------VVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPY</Hsp_hseq>
      <Hsp_midline>M    +Y   +++G G++ VVY      TG + A+K I+     + +++  ++E+  L+ ++    H NV+   +           MA D+      +L   +E  +K +           W++M                              R V   HRN I+HRDLKP+N+L + +     +KVADFGL++      + L+S              + +Y APE+  G  H+T+  DI+++G+I   ++ RI +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>4.83543e-11</Hsp_evalue>
      <Hsp_query-from>263</Hsp_query-from>
      <Hsp_query-to>1057</Hsp_query-to>
      <Hsp_hit-from>49</Hsp_hit-from>
      <Hsp_hit-to>291</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>124</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>279</Hsp_align-len>
      <Hsp_qseq>KYELLRELGRGSFGVVYEAVVRGTGARRAVK---RIRCCSPESVELGL------QELWALKSVRPPRGHH-NVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVW----EGHFTAKADIFALGIIVWAMLERITFTDAESKRKLLGSYVRQ</Hsp_qseq>
      <Hsp_hseq>NFEILATLGNGQYGKVKLARDLGTGALVAIKILNRFEKRSGYSLQLKVENPRVNQEIEVMK-----RCHHENVVELYEIL------------NDPESTKVYL-VLEYCSRGPVKWCPENKMEIKAV-----GPSILTFQQSRK--------VVLDVVSGLEYLHSQGITHRDIKPSNLLISSNG---TVKISDFGVAMSTATGSTNIQS--SHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPFNANSGLELFDSIINK</Hsp_hseq>
      <Hsp_midline> +E+L  LG G +G V  A   GTGA  A+K   R    S  S++L +      QE+  +K     R HH NVV   E +            +D E  + YL ++E   +G   + P N   +  V     G  +  +  SR+          + +   + +LH   I HRD+KP N+L++ N     +K++DFG++   A     + S  S  +   S A G+  + APE+     E   ++  DI++LG+ ++ +L      +A S  +L  S + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>5.34762e-11</Hsp_evalue>
      <Hsp_query-from>263</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>12</Hsp_hit-from>
      <Hsp_hit-to>220</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>249</Hsp_align-len>
      <Hsp_qseq>KYELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGL-QELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYL--RLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEG--HFTAKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>QYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQ---PFSKKLFVTRTIREIKLLRYFHEHENIISILDKV-----RPVSIDK----LNAVYLVEELMETDL--QKVINNQNSGFSTL------SDDHVQY-------------FTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCD---LKVCDFGLARCLASS----SDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMV</Hsp_hseq>
      <Hsp_midline>+Y+L+  +G G++G V  A+ + +G + A+K+I+   P S +L + + +  +K +R    H N++   + V     R   + +        YL   L+ET L  ++     NS +  L        D   Y             F  Q+ RA+  +H   ++HRD+KP N+L+  N     LKV DFGL++  A      S        +++    + +Y APE+      +T   DI++ G I+  M+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>6.52308e-11</Hsp_evalue>
      <Hsp_query-from>587</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>121</Hsp_hit-from>
      <Hsp_hit-to>246</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>143</Hsp_align-len>
      <Hsp_qseq>NSYYLWLVMEYCDGGDMNGYLLSRQPDHWLNTSFA----MQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEV---WEGHFTAKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>NSKYIGIVLEFVSGGEFYKYI---QRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHEN---LVITDFGFVNEFFEDNE-----------LMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAML</Hsp_hseq>
      <Hsp_midline>NS Y+ +V+E+  GG+   Y+   Q    L  S A     QL   V ++H   +VHRDLK +N+L+ ++     L + DFG    F    +            +  +CGS  Y APE+    + +   KAD+++ G+I++AML</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YFL033C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:69115:74427:-1 gene:YFL033C transcript:YFL033C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM15 description:Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase [Source:SGD;Acc:S000001861]</Hit_def>
  <Hit_accession>YFL033C</Hit_accession>
  <Hit_len>1770</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>7.42584e-11</Hsp_evalue>
      <Hsp_query-from>266</Hsp_query-from>
      <Hsp_query-to>826</Hsp_query-to>
      <Hsp_hit-from>794</Hsp_hit-from>
      <Hsp_hit-to>941</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>51</Hsp_gaps>
      <Hsp_align-len>193</Hsp_align-len>
      <Hsp_qseq>YELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGD------MNGYLLSRQPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSK</Hsp_qseq>
      <Hsp_hseq>YDILKPISKGAYGSVYLARKKLTGDYFAIKVLR----KSDMIAKNQVTNVKS---------------------ERAIMMVQSD----KPYVARLFASFQ--------NKDNLFLVMEYLPGGDLATLIKMMGYL----PDQWAK-QYLTEIVVGVNDMHQNGIIHHDLKPENLLI-DNAGH--VKLTDFGLSR</Hsp_hseq>
      <Hsp_midline>Y++L+ + +G++G VY A  + TG   A+K +R    +S  +   ++  +KS                      RA  M + D    + Y+  +  S +        N   L+LVMEY  GGD      M GYL    PD W    +  ++   V  +H+N I+H DLKP+N+L+ +N+G   +K+ DFGLS+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>9.7443e-11</Hsp_evalue>
      <Hsp_query-from>704</Hsp_query-from>
      <Hsp_query-to>982</Hsp_query-to>
      <Hsp_hit-from>335</Hsp_hit-from>
      <Hsp_hit-to>412</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>94</Hsp_align-len>
      <Hsp_qseq>RAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEGH-FTAKADIFALGIIV</Hsp_qseq>
      <Hsp_hseq>RGLSYLHEKKVIHRDIKPQNILLNENGQ---VKLCDFGV------------SGEAVN-SLATTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTI</Hsp_hseq>
      <Hsp_midline>R +++LH   ++HRD+KP NIL+ EN     +K+ DFG+            SGE+VN +  +   G+SFYMAPE  +G  ++  +D+++LG+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>1.14828e-10</Hsp_evalue>
      <Hsp_query-from>263</Hsp_query-from>
      <Hsp_query-to>997</Hsp_query-to>
      <Hsp_hit-from>22</Hsp_hit-from>
      <Hsp_hit-to>212</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>64</Hsp_gaps>
      <Hsp_align-len>250</Hsp_align-len>
      <Hsp_qseq>KYELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESV--ELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEV---WEGHFTAKADIFALGIIVWAMLE</Hsp_qseq>
      <Hsp_hseq>RYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLR----HENLI----CL-----------------QDIFLSPLED---------------IYFVTE-LQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCD---LKICDFGLARIQDPQMTGYVS--------------TRYYRAPEIMLTWQK-YDVEVDIWSAGCIFAEMIE</Hsp_hseq>
      <Hsp_midline>+Y  L  +G G+FG+V  A    T    A+K+I      +V  +   +EL  LK +R    H N++    C+                  + +L  +E                ++ V E   G D++  L +R  +      F  Q+ R + ++H   ++HRDLKP NIL+ EN     LK+ DFGL++I   Q  G  S              + +Y APE+   W+  +  + DI++ G I   M+E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>1.16875e-10</Hsp_evalue>
      <Hsp_query-from>266</Hsp_query-from>
      <Hsp_query-to>991</Hsp_query-to>
      <Hsp_hit-from>412</Hsp_hit-from>
      <Hsp_hit-to>605</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>62</Hsp_gaps>
      <Hsp_align-len>249</Hsp_align-len>
      <Hsp_qseq>YELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYY----LWLVMEYCDGGDMNGYLLSRQPDHWLNTSFAM-QLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVW--EGHFTAKADIFALGIIVWAM</Hsp_qseq>
      <Hsp_hseq>FEVLRLLGKGTFGQVYQVKKKDT---------------------QRIYAMK-----------VLSKKVIVKKNEIAHTI-------GERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGN---IALCDFGLSK-----------ADLKDRT--NTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEM</Hsp_hseq>
      <Hsp_midline>+E+LR LG+G+FG VY+   + T                     Q ++A+K           V   + +++ N  A  +       GE  + +   S       G   S+     L+LV +Y  GG++  +L            F + +L  A+  LH N IV+RDLKP+NIL+  N     + + DFGLSK            +  +R   +  CG++ Y+APE+   E  +T   D ++LG++++ M</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>1.68583e-10</Hsp_evalue>
      <Hsp_query-from>266</Hsp_query-from>
      <Hsp_query-to>997</Hsp_query-to>
      <Hsp_hit-from>546</Hsp_hit-from>
      <Hsp_hit-to>763</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>84</Hsp_gaps>
      <Hsp_align-len>273</Hsp_align-len>
      <Hsp_qseq>YELLRELGRGSFGVVYEA-------------VVRG------TGARRAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLNTS---------FAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEG-HFTAKADIFALGIIVWAMLE</Hsp_qseq>
      <Hsp_hseq>FKVIEKAGQGASGSVYLAERTHIPTESNMIELINNDIDEPHVGDKVAIKQMVLSKQPRKELIVNEILVMKDSR----HKNIVNF---------------------LEAYLRTDDD---------------LWVVMEFMEGGSLTD-IIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLL---DTRARVKITDFGFCARLTDK-----------RSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLE</Hsp_hseq>
      <Hsp_midline>++++ + G+G+ G VY A             ++         G + A+K++        EL + E+  +K  R    H N+V F                      EAYLR  +                LW+VME+ +GG +   ++   P +  + S            +  + + FLH   I+HRD+K DN+L+     R  +K+ DFG       +           R+  +   G+ ++MAPEV +   +  K D+++LGI+   MLE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>1.75473e-10</Hsp_evalue>
      <Hsp_query-from>266</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>824</Hsp_hit-from>
      <Hsp_hit-to>1018</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>58</Hsp_gaps>
      <Hsp_align-len>248</Hsp_align-len>
      <Hsp_qseq>YELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETS---LKGERC-FGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVW-EGHFTAKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>FVLLKVLGKGNFGKVILSKSKNTDRLCAIK-------------------------------VLKKDNIIQNHDIESARAEK------KVFLLATKTKHPFLTNLYCSFQTENRIYF--AMEFIGGGDLMWHVQNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGH---IKIADYGLCKDEMWYG---------NRT--STFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQML</Hsp_hseq>
      <Hsp_midline>+ LL+ LG+G+FG V  +  + T    A+K                               V++ D  +  H+  +AR  +      + +L   +T    L    C F   N  Y    ME+  GGD+  ++ +++        +A ++  A+ + H N +++RDLK +NIL+        +K+AD+GL K     G         NR   S  CG+  +MAPE+  E  +T   D +A G++++ ML</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>1.76494e-10</Hsp_evalue>
      <Hsp_query-from>599</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>227</Hsp_hit-from>
      <Hsp_hit-to>356</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>134</Hsp_align-len>
      <Hsp_qseq>LWLVMEYCDGGDMNGYLLSRQP-DHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEGH-FTAKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>LYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQ---RGHLVLTDFGLSKKSANDS-AVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDML</Hsp_hseq>
      <Hsp_midline>L+L+++Y  GG++  +L      D    + +A ++S A+ FLH   +V+RDLKP+N L+ +   R  L + DFGLSK  A     +   +  N   L    G+  Y APE+  G  ++   D ++LG +++ ML</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>1.97245e-10</Hsp_evalue>
      <Hsp_query-from>278</Hsp_query-from>
      <Hsp_query-to>997</Hsp_query-to>
      <Hsp_hit-from>45</Hsp_hit-from>
      <Hsp_hit-to>244</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>62</Hsp_gaps>
      <Hsp_align-len>251</Hsp_align-len>
      <Hsp_qseq>RELGRGSFGVVYEAVVRGTGAR----RAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFD-----ECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVW--EGHFTAKADIFALGIIVWAMLE</Hsp_qseq>
      <Hsp_hseq>KRIGHGSFGTVTQSILSSNSIEWLGPYAIKRV-VKSPKVQSL---ELEILQNIRHP----NLVTLEFFFESHCTTKDGGHL-------YQKNFV-MEYIPQTLSSE-------------IHEYFDNG-------SKMPTKHIKL-YTFQILRALLTLHSMSICHGDLKPSNILIIPSSG--IAKVCDF-------GSAQRLDDNTELKTYF----C-SRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIK</Hsp_hseq>
      <Hsp_midline>+ +G GSFG V ++++           A+KR+   SP+   L   EL  L+++R P    N+V  +      C  +  G         Y++    +  +  +L  E             + EY D G       S+ P   +   +  Q+ RA+  LH  SI H DLKP NIL+  +SG  + KV DF       G  Q L     +   +    C S FY APE+      +T + DI++LG I+  M++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>2.38704e-10</Hsp_evalue>
      <Hsp_query-from>266</Hsp_query-from>
      <Hsp_query-to>1000</Hsp_query-to>
      <Hsp_hit-from>60</Hsp_hit-from>
      <Hsp_hit-to>279</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>251</Hsp_align-len>
      <Hsp_qseq>YELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGLQELWALKSVRPPR--GHHNVVRFDECVLQHNGRAARMARDDYERG-EAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLS-SGESVNRAWLSPACGSSFYMAPEVWEG--HFTAKADIFALGIIVWAMLER</Hsp_qseq>
      <Hsp_hseq>YREDEKLGQGTFGEVYKGIHLETQRQVAMKKIIV----SVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGV-LHNP------RINLEMCDIKNM-----------------MLQILEGLNYIHCAKFMHRDIKTANILIDHNG---VLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEK</Hsp_hseq>
      <Hsp_midline>Y    +LG+G+FG VY+ +   T  + A+K+I      SVE  L  + A + +   +   H N+++  E V  H+      A  +  +     L  +   L G     P       + +E CD  +M                  +Q+   + ++H    +HRD+K  NIL+  N    VLK+ADFGL++++ G    L   G + + A  +    + +Y APE+  G   +T   DI+ +G +     E+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>2.5913e-10</Hsp_evalue>
      <Hsp_query-from>575</Hsp_query-from>
      <Hsp_query-to>982</Hsp_query-to>
      <Hsp_hit-from>280</Hsp_hit-from>
      <Hsp_hit-to>405</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>FGPGNSYYLWLVMEYCDGGDMNGY---LLSR--QPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEGH-FTAKADIFALGIIV</Hsp_qseq>
      <Hsp_hseq>FTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNE---KGEIKLCDFGV------------SGEAVNSLAMT-FTGTSFYMAPERIQGQPYSVTCDVWSLGLTL</Hsp_hseq>
      <Hsp_midline>F    S  +++ MEY  G  +      LL R  +    +    A  + R +++LH   ++HRD+KP NIL+ E   +  +K+ DFG+            SGE+VN   ++   G+SFYMAPE  +G  ++   D+++LG+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>3.73926e-10</Hsp_evalue>
      <Hsp_query-from>596</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>568</Hsp_hit-from>
      <Hsp_hit-to>711</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>147</Hsp_align-len>
      <Hsp_qseq>YLWLVMEYCDGGDMNGYLLSRQPDHWLNTS---FAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSF----------YMAPEVWEGH-FTAKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>YLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQ-SGHIML--SDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEML</Hsp_hseq>
      <Hsp_midline>YL+L MEYC GG+    L +R+           +A +++ A+ +LH    ++RDLKP+NIL+ + SG  +L  +DF LS         +  G + +    +  C   F          Y+APEV  G+  TA  D + LGI+++ ML</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>4.21662e-10</Hsp_evalue>
      <Hsp_query-from>266</Hsp_query-from>
      <Hsp_query-to>1000</Hsp_query-to>
      <Hsp_hit-from>38</Hsp_hit-from>
      <Hsp_hit-to>246</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>250</Hsp_align-len>
      <Hsp_qseq>YELLRELGRGSFGVVYEAVVRG--TGARRAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETS-LKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEGH--FTAKADIFALGIIVWAMLER</Hsp_qseq>
      <Hsp_hseq>YEIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNKEILLK-RAIRELKFMNFFKGHKNIVNLID-----------------------LEIVTSSPYDGLYCYQELIDYDLAKVIHS-----------SVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNG---CLKICDFGLAR---GIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYAR</Hsp_hseq>
      <Hsp_midline>YE+++ LG+G++G V     +G    AR AVK+I     + + L  + +  LK +   +GH N+V   +                       L +V +S   G  C+     Y L  V+             S Q   +    F  Q+   + ++H   ++HRDLKP NIL   N     LK+ DFGL++   G   G     S  +  ++    + +Y APE+   +  ++   DI+A+G I+     R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>5.71234e-10</Hsp_evalue>
      <Hsp_query-from>596</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>396</Hsp_hit-from>
      <Hsp_hit-to>536</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>148</Hsp_align-len>
      <Hsp_qseq>YLWLVMEYCDGGDMNGYLLSRQPDHWLNTS---FAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWL-SPACGSSF----------YMAPEVWEGH-FTAKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>YLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQ-SGHVML--SDFDLSI----QATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEML</Hsp_hseq>
      <Hsp_midline>YL+L MEYC GG+    L +R+           +A ++  A+ +LH    ++RDLKP+NIL+ + SG  +L  +DF LS     Q  G       +  +L +  C   F          Y+APEV  G+  TA  D + LGI+++ ML</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>1.35915e-09</Hsp_evalue>
      <Hsp_query-from>683</Hsp_query-from>
      <Hsp_query-to>1078</Hsp_query-to>
      <Hsp_hit-from>265</Hsp_hit-from>
      <Hsp_hit-to>391</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>138</Hsp_align-len>
      <Hsp_qseq>SFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEG--HFTAKADIFALGIIVWAMLE-RITFTDAESK---RKLLGSYVRQGRRIVPV</Hsp_qseq>
      <Hsp_hseq>SIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDG---CVKIGDLGLARKFHNMLQTLYTGDKV--------VVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELIGLQPIFKGEEAKLDSKKTVPFQVNQLQRILEV</Hsp_hseq>
      <Hsp_midline>S   QL   V++LH+N ++HRDLKP NI+V  +     +K+ D GL++ F    Q L +G+ V          + +Y APE+  G  H+T   D++++G I   ++  +  F   E+K   +K +   V Q +RI+ V</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>1.8839e-09</Hsp_evalue>
      <Hsp_query-from>686</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>144</Hsp_hit-from>
      <Hsp_hit-to>234</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>105</Hsp_align-len>
      <Hsp_qseq>FAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEG--HFTAKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>YTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETG--VLKICDFGSAKKLEH-----------NQPSISYIC-SRFYRAPELIIGCTQYTTQIDIWGLGCVMGEML</Hsp_hseq>
      <Hsp_midline>+  Q++R + +LH   + HRD+KP N+LV   +G  VLK+ DFG +K               N+  +S  C S FY APE+  G   +T + DI+ LG ++  ML</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>3.2613e-09</Hsp_evalue>
      <Hsp_query-from>602</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>157</Hsp_hit-from>
      <Hsp_hit-to>283</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>144</Hsp_align-len>
      <Hsp_qseq>WLVMEYCDGGDMNGYLLSRQ-PDHWLN-TSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRP-VLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEGHFT----------AKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>YIIMEYCSGGDLYEAIKADAVPKKTKSITHIITQIMDAIEYVHNKGIYHRDIKPENILI---SGIDWTIKLTDWGLA--------------TTDKTSMDRNVGSERYMSPELFDSNLDIKERKEPYDCAKVDLWAMGIVFLNIV</Hsp_hseq>
      <Hsp_midline>+++MEYC GGD+   + +   P    + T    Q+  A+ ++H   I HRD+KP+NIL+   SG    +K+ D+GL+              + ++  +    GS  YM+PE+++ +            AK D++A+GI+   ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>1.95119e-08</Hsp_evalue>
      <Hsp_query-from>266</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>344</Hsp_hit-from>
      <Hsp_hit-to>536</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>58</Hsp_gaps>
      <Hsp_align-len>247</Hsp_align-len>
      <Hsp_qseq>YELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHN-GRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLNTS--FAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEGH-FTAKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>FDLLKVIGKGSFGKVMQVRKKDT---------------------QKIYALKALR------KAYIVSKCEVTHTLAERTVLARVDC----PFIVPLKFSFQSPE--------KLYLVLAFINGGEL-FYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILL-DYQGH--IALCDFGLCKLNMKDNDKTDT-----------FCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMM</Hsp_hseq>
      <Hsp_midline>++LL+ +G+GSFG V +   + T                     Q+++ALK++R            +C + H       +AR D      ++  ++ S +            L+LV+ + +GG++  Y L  +    L  S  +  +L  A+  LH+  +++RDLKP+NIL+ +  G   + + DFGL K+         +            CG+  Y+APE+  G  +T   D + LGI+++ M+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>3.31484e-08</Hsp_evalue>
      <Hsp_query-from>575</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>256</Hsp_hit-from>
      <Hsp_hit-to>414</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>174</Hsp_align-len>
      <Hsp_qseq>FGPGNSYYLWLVMEYCDGGDMNGYLLSRQP-DHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVA----ENSGRPVL---------------------------KVADFGLSK-IFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEG-HFTAKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>FQETDSYY-YIIQELLTGGEIFGEIVRLTYFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKNTKT--------------PCGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTML</Hsp_hseq>
      <Hsp_midline>F   +SYY +++ E   GG++ G ++        L+     QL+ AV  +H   +VHRD+KP+N+L        S +P L                           K+ADFGLSK IF+   +                CG+  Y APEV +  H++ K D++ +G +++ ML</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>6.07533e-08</Hsp_evalue>
      <Hsp_query-from>599</Hsp_query-from>
      <Hsp_query-to>997</Hsp_query-to>
      <Hsp_hit-from>88</Hsp_hit-from>
      <Hsp_hit-to>225</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>143</Hsp_align-len>
      <Hsp_qseq>LWLVMEYCDGGDMNGYL--LSRQPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIF-------AGQGQGLSSGESVNRAWLSPACGSSFYMAPE-VWEGHFTAKADIFALGIIVWAMLE</Hsp_qseq>
      <Hsp_hseq>LYFVLDFAPGGELLSLLHKMGTFNDIWTR-HFTAQLIDALEFIHSHGIIHRDLKPENVLL-DRDGR--LMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCAS-FVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQ</Hsp_hseq>
      <Hsp_midline>L+ V+++  GG++   L  +    D W    F  QL  A+ F+H + I+HRDLKP+N+L+ +  GR  L + DFG +          + +    S+G   N+   S   G++ Y++PE +        +DI+ALG +++  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YKL168C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:131288:133462:-1 gene:YKL168C transcript:YKL168C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KKQ8 description:Putative serine/threonine protein kinase with unknown cellular role; KKQ8 has a paralog, HAL5, that arose from the whole genome duplication [Source:SGD;Acc:S000001651]</Hit_def>
  <Hit_accession>YKL168C</Hit_accession>
  <Hit_len>724</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>6.97096e-08</Hsp_evalue>
      <Hsp_query-from>608</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>512</Hsp_hit-from>
      <Hsp_hit-to>638</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>137</Hsp_align-len>
      <Hsp_qseq>VMEYCDGGDMNGYLLSRQPD----HWLNTS-FAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVW-EGHFTAK--ADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>VMEFCPAGDLYGMLVGKSKLKGRLHPLEADCFMKQLLHGVKFMHDHGIAHCDLKPENILFYPHG---LLKICDFGTSSVFQTAWERRVHAQKG-------IIGSEPYVAPEEFVDGEYYDPRLIDCWSCGVVYITMI</Hsp_hseq>
      <Hsp_midline>VME+C  GD+ G L+ +       H L    F  QL   V F+H + I H DLKP+NIL   +    +LK+ DFG S +F    +     +           GS  Y+APE + +G +      D ++ G++   M+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YDL214C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:74446:76545:-1 gene:YDL214C transcript:YDL214C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR2 description:Serine/threonine protein kinase; inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance; PRR2 has a paralog, NPR1, that arose from the whole genome duplication [Source:SGD;Acc:S000002373]</Hit_def>
  <Hit_accession>YDL214C</Hit_accession>
  <Hit_len>699</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>1.07639e-07</Hsp_evalue>
      <Hsp_query-from>599</Hsp_query-from>
      <Hsp_query-to>1000</Hsp_query-to>
      <Hsp_hit-from>436</Hsp_hit-from>
      <Hsp_hit-to>560</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>138</Hsp_align-len>
      <Hsp_qseq>LWLVMEYCDGGDMNGYLLSRQPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAG--QGQGLSSGESVNRAWLSPACGSSFYMAPEV-WEGHFTAKA-DIFALGIIVWAMLER</Hsp_qseq>
      <Hsp_hseq>IFQILEYCEY-DLFSLVMSEKMHYEEICCLFKQLINGVKYLHDIGLSHRDLKLDNCVVTR---RGILKLIDFGASSVFHYPLSSQMIEANGIV---------GSDPYLSPEVFYFNEYDPRALDVWSVGIIFFCMITR</Hsp_hseq>
      <Hsp_midline>++ ++EYC+  D+   ++S +  +        QL   V +LH   + HRDLK DN +V     R +LK+ DFG S +F      Q + +   V         GS  Y++PEV +   +  +A D++++GII + M+ R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>1.58433e-07</Hsp_evalue>
      <Hsp_query-from>596</Hsp_query-from>
      <Hsp_query-to>1006</Hsp_query-to>
      <Hsp_hit-from>236</Hsp_hit-from>
      <Hsp_hit-to>383</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>149</Hsp_align-len>
      <Hsp_qseq>YLWLVMEYCDGGDMNGYLLSRQPDHWLNTS----FAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACG--------SSFYMAPEVWEGHFTAKADIFALGIIVWAMLERIT</Hsp_qseq>
      <Hsp_hseq>HLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKERMHTVVGTPE-YCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGIS</Hsp_hseq>
      <Hsp_midline>+L++  +   GGD+  YL        ++ +       Q+ +A+ +LH   IVHRDLK DNIL+        + +ADFG++K      + + +       + +P  G         SF  A  + +  + +K D+++LG+I   ML  I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>2.06883e-07</Hsp_evalue>
      <Hsp_query-from>596</Hsp_query-from>
      <Hsp_query-to>832</Hsp_query-to>
      <Hsp_hit-from>424</Hsp_hit-from>
      <Hsp_hit-to>500</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>80</Hsp_align-len>
      <Hsp_qseq>YLWLVMEYCDGGDMNGYLLSRQPDHWLNTSFAM-QLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIF</Hsp_qseq>
      <Hsp_hseq>YLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILI---DIRGHIKLSDFGLSTGF</Hsp_hseq>
      <Hsp_midline>YL+L+ME+  GGD+   L+  Q      T F M +   A+  +H+   +HRD+KPDNIL+     R  +K++DFGLS  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>2.45474e-07</Hsp_evalue>
      <Hsp_query-from>266</Hsp_query-from>
      <Hsp_query-to>1000</Hsp_query-to>
      <Hsp_hit-from>183</Hsp_hit-from>
      <Hsp_hit-to>377</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>68</Hsp_gaps>
      <Hsp_align-len>254</Hsp_align-len>
      <Hsp_qseq>YELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGLQELWALKSVRPPR-----GHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSR--QPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEG--HFTAKADIFALGIIVWAMLER</Hsp_qseq>
      <Hsp_hseq>YLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRL-------QGEREGFPITSIREIKLLQSFDHPNVSTIKEIMVESQKT------------------------------------VYMIFEYADN-DLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILI-DNQGN--LKITDFGLARKMN------SRADYTNRVI------TLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNK</Hsp_hseq>
      <Hsp_midline>Y  + ++G G++G VY+A    T    A+K++R         G +E + + S+R  +      H NV    E +++                                        ++++ EY D  D++G LL++  Q  H        QL   + +LH N I+HRD+K  NIL+ +N G   LK+ DFGL++         S  +  NR        + +Y  PE+  G  ++  + D++  G ++  +  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YJR059W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:545787:548243:1 gene:YJR059W transcript:YJR059W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK2 description:Serine/threonine protein kinase; involved in regulation of ion transport across plasma membrane; carboxyl terminus is essential for glucose-dependent Pma1p activation via phosphorylation of Pma1p-Ser899; enhances spermine uptake; PTK2 has a paralog, PTK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003820]</Hit_def>
  <Hit_accession>YJR059W</Hit_accession>
  <Hit_len>818</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>2.50355e-07</Hsp_evalue>
      <Hsp_query-from>671</Hsp_query-from>
      <Hsp_query-to>1018</Hsp_query-to>
      <Hsp_hit-from>357</Hsp_hit-from>
      <Hsp_hit-to>485</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>WLNTSFA------MQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVW----EGHFTAK---------ADIFALGIIVWAMLERIT-FTDA</Hsp_qseq>
      <Hsp_hseq>WKNVPFNEKYCLFKQVAQGIKFCHDNGIAHRDLKPENVLISKEG---ICKLTDFGISDWYHVIPHDYTSPVKTCQGMI----GSPPYTPPEVMYFDAKKHYPEKFQKPYNPLAMDSYALGIMLITMINNIIPFIDS</Hsp_hseq>
      <Hsp_midline>W N  F        Q+++ + F H N I HRDLKP+N+L+++     + K+ DFG+S  +       +S     +  +    GS  Y  PEV     + H+  K          D +ALGI++  M+  I  F D+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>2.92927e-07</Hsp_evalue>
      <Hsp_query-from>578</Hsp_query-from>
      <Hsp_query-to>1000</Hsp_query-to>
      <Hsp_hit-from>99</Hsp_hit-from>
      <Hsp_hit-to>229</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>143</Hsp_align-len>
      <Hsp_qseq>GPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEGH--FTAKADIFALGIIVWAMLER</Hsp_qseq>
      <Hsp_hseq>GALNGVYLYEELMECDLSQIIRSEQRLEDAHF--QSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQ---LKICNFGLSCSY-------SENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGR</Hsp_hseq>
      <Hsp_midline>G  N  YL+  +  CD   +       +  H+   SF  Q+  A+ ++H  +++H DLKP N+LV  +     LK+ +FGLS  +       S    VN  ++     S +Y APE+   +   T   DI++ G I+  +L R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>3.80427e-07</Hsp_evalue>
      <Hsp_query-from>266</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>347</Hsp_hit-from>
      <Hsp_hit-to>539</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>56</Hsp_gaps>
      <Hsp_align-len>246</Hsp_align-len>
      <Hsp_qseq>YELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGLQELWALKSVRPPRGHHNVVRFDECVLQHNGRAARMARDDYERGEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLNTS--FAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEG-HFTAKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>FDLLKVIGKGSFGKVMQVRKKDT---------------------QKVYALKAIR----KSYIVSKSEVTHTLAERTV-LARVDC----PFIVPLKFSFQSPEK--------LYFVLAFINGGEL-FYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILL-DYQGH--IALCDFGLCKLNMKDDDKTDT-----------FCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEML</Hsp_hseq>
      <Hsp_midline>++LL+ +G+GSFG V +   + T                     Q+++ALK++R       +V   E       R   +AR D      ++  ++ S +            L+ V+ + +GG++  Y L ++    L+ +  +  +L  A+  LH+  +V+RDLKP+NIL+ +  G   + + DFGL K+         +            CG+  Y+APE+  G  +T   D + LG++++ ML</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>71</Hit_num>
  <Hit_id>YKL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:347214:349136:-1 gene:YKL048C transcript:YKL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ELM1 description:Serine/threonine protein kinase; regulates the orientation checkpoint, the morphogenesis checkpoint and the metabolic switch from fermentative to oxidative metabolism by phosphorylating the activation loop of Kin4p, Hsl1p and Snf4p respectively; cooperates with Hsl7p in recruiting Hsl1p to the septin ring, a prerequisite for subsequent recruitment, phosphorylation, and degradation of Swe1p; forms part of the bud neck ring; regulates cytokinesis [Source:SGD;Acc:S000001531]</Hit_def>
  <Hit_accession>YKL048C</Hit_accession>
  <Hit_len>640</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>4.45904e-07</Hsp_evalue>
      <Hsp_query-from>536</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>182</Hsp_hit-from>
      <Hsp_hit-to>348</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>180</Hsp_align-len>
      <Hsp_qseq>LRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPD-----HWLN--------TSFAMQ----LSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSG--ESVNRAWLSPACGSSFYMAPEVW-----EGHFTA---KADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>VRLIE-------CLDSPFSESIWIVTNWCSLGELQ---WKRDDDEDILPQWKKIVISNCSVSTFAKKILEDMTKGLEYLHSQGCIHRDIKPSNILLDEEEK--VAKLSDFG-SCIFTPQSLPFSDANFEDCFQRELNKIVGTPAFIAPELCHLGNSKRDFVTDGFKLDIWSLGVTLYCLL</Hsp_hseq>
      <Hsp_midline>+RL+E       C     S  +W+V  +C  G++      R  D      W          ++FA +    +++ + +LH    +HRD+KP NIL+ E     V K++DFG S IF  Q    S    E   +  L+   G+  ++APE+      +  F     K DI++LG+ ++ +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>72</Hit_num>
  <Hit_id>YJL165C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:106894:109461:-1 gene:YJL165C transcript:YJL165C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HAL5 description:Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters; HAL5 has a paralog, KKQ8, that arose from the whole genome duplication [Source:SGD;Acc:S000003701]</Hit_def>
  <Hit_accession>YJL165C</Hit_accession>
  <Hit_len>855</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>4.59822e-07</Hsp_evalue>
      <Hsp_query-from>608</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>619</Hsp_hit-from>
      <Hsp_hit-to>763</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>161</Hsp_align-len>
      <Hsp_qseq>VMEYCDGGDMNGYLL----------------------SRQPDHWLNTS-FAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAW------LSPACGSSFYMAPE--VWEGHFTAK-ADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>VMEFCASGDLYSLLTRNNISNESNNGSSRLIQTVKEGSGSPLHPLEADCFMKQLLNGVQYMHDHGIAHCDLKPENILFQPNG---LLKICDFGTSSVFQ-------------TAWEKHVHFQSGAMGSEPYVAPEEFIRDAEYDPRLVDCWSCGIVYCTMV</Hsp_hseq>
      <Hsp_midline>VME+C  GD+   L                       S  P H L    F  QL   V ++H + I H DLKP+NIL   N    +LK+ DFG S +F               AW       S A GS  Y+APE  + +  +  +  D ++ GI+   M+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>73</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>6.98146e-07</Hsp_evalue>
      <Hsp_query-from>599</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>267</Hsp_hit-from>
      <Hsp_hit-to>398</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>150</Hsp_align-len>
      <Hsp_qseq>LWLVMEYCDGGDMN------------GYLLSRQPDHWLN----TSFAMQLSRAVAFLHRN-SIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEGH-FTAKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>IIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKT--WFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLI---NSKGQIKLCDFGVSKKLIN-------------SIADTFVGTSTYMSPERIQGNVYSIKGDVWSLGLMIIELV</Hsp_hseq>
      <Hsp_midline>+ ++MEY D G ++            G + S++   W N    +  A  +   +  L+R   I+HRD+KP N+L+   + +  +K+ DFG+SK                 +      G+S YM+PE  +G+ ++ K D+++LG+++  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>74</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>9.0603e-07</Hsp_evalue>
      <Hsp_query-from>599</Hsp_query-from>
      <Hsp_query-to>991</Hsp_query-to>
      <Hsp_hit-from>431</Hsp_hit-from>
      <Hsp_hit-to>557</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>LWLVMEYCDGGDMNGYLLSRQPDHWLNTSFAMQLSRAV-----AFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWE------GHFTAKADIFALGIIVWAM</Hsp_qseq>
      <Hsp_hseq>VYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSANQG--TVKLCDFGVS------GNLVASLAKTN-------IGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEM</Hsp_hseq>
      <Hsp_midline>+++ MEY DGG ++           ++      ++ AV         +++I+HRD+KP NIL + N G   +K+ DFG+S      G  ++S    N        G   YMAPE  +        +T ++DI++LG+ +  M</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>75</Hit_num>
  <Hit_id>YHR079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:258244:261591:-1 gene:YHR079C transcript:YHR079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IRE1 description:Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; role in homeostatic adaptation to ER stress; Kar2p binds inactive Ire1p and releases from it upon ER stress [Source:SGD;Acc:S000001121]</Hit_def>
  <Hit_accession>YHR079C</Hit_accession>
  <Hit_len>1115</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>1.21048e-06</Hsp_evalue>
      <Hsp_query-from>683</Hsp_query-from>
      <Hsp_query-to>934</Hsp_query-to>
      <Hsp_hit-from>776</Hsp_hit-from>
      <Hsp_hit-to>862</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>94</Hsp_align-len>
      <Hsp_qseq>SFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENS--------GRPVLK--VADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWE</Hsp_qseq>
      <Hsp_hseq>SLLRQIASGVAHLHSLKIIHRDLKPQNILVSTSSRFTADQQTGAENLRILISDFGLCK-------KLDSGQSSFRTNLNNPSGTSGWRAPELLE</Hsp_hseq>
      <Hsp_midline>S   Q++  VA LH   I+HRDLKP NILV+ +S        G   L+  ++DFGL K        L SG+S  R  L+   G+S + APE+ E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>76</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>1.80893e-06</Hsp_evalue>
      <Hsp_query-from>575</Hsp_query-from>
      <Hsp_query-to>1030</Hsp_query-to>
      <Hsp_hit-from>68</Hsp_hit-from>
      <Hsp_hit-to>229</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>180</Hsp_align-len>
      <Hsp_qseq>FGPGNSYYLWLVMEYCDGGDMNGYL-LSRQPDHWLNTSFAM--------QLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWEG------------------HFTAKADIFALG-IIVWAMLERITFTDAESKR</Hsp_qseq>
      <Hsp_hseq>FYTDDSYYI-MVLEYCECGDLYDFLDIAKSQGSPSSPSLIQIDMQKIIKQLCSAISFAHSLGIAHRDIKPENILLTINGD---IKLADW---------GHAIQSPKSNDF-----QIGTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFGDCLFRVSKSKK</Hsp_hseq>
      <Hsp_midline>F   +SYY+ +V+EYC+ GD+  +L +++      + S           QL  A++F H   I HRD+KP+NIL+  N     +K+AD+         G  + S +S +        G+  Y APE + G                  + T +AD ++LG  I + M     F  ++SK+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>77</Hit_num>
  <Hit_id>YDL025C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:405344:407206:-1 gene:YDL025C transcript:YDL025C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RTK1 description:Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002183]</Hit_def>
  <Hit_accession>YDL025C</Hit_accession>
  <Hit_len>620</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>4.12199e-06</Hsp_evalue>
      <Hsp_query-from>584</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>379</Hsp_hit-from>
      <Hsp_hit-to>504</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>139</Hsp_align-len>
      <Hsp_qseq>GNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVWE--GHFTAKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>GDTY--LLVMEYAPYDFFNLVMSNLMTQDEVNCYFK-QLCHGVNYLHSMGLAHRDLKLDNCVVTKDG---ILKLIDFGSAVVFQYPYE-----DTIVKSH--GIVGSDPYLAPELLKQTSYDPRVADVWSIAIIFYCMV</Hsp_hseq>
      <Hsp_midline>G++Y   LVMEY      N  + +      +N  F  QL   V +LH   + HRDLK DN +V ++    +LK+ DFG + +F    +     +++ ++      GS  Y+APE+ +   +    AD++++ II + M+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>78</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>5.1012e-06</Hsp_evalue>
      <Hsp_query-from>263</Hsp_query-from>
      <Hsp_query-to>979</Hsp_query-to>
      <Hsp_hit-from>37</Hsp_hit-from>
      <Hsp_hit-to>274</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>67</Hsp_gaps>
      <Hsp_align-len>272</Hsp_align-len>
      <Hsp_qseq>KYELLRELGRGSFGVVYEAVVRGTGARRAVKRIRCCSPESVELGLQ-ELWALKSVRPPRGHHNVVRFDECVLQHNGRAARM-ARDDYER------------GEAYLRLVETSLKGERCFGPGNSYYLWLVMEYCDGGDMNGYLLSRQPDHWLNTSFAMQLSRAVA---FLHRNSIVHRDLKPDNILVAENS--------------GRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEVW--EGHFTAKADIFALGII</Hsp_qseq>
      <Hsp_hseq>RYQLIEKLGAGSFGCVTLA--------------KAQFPLSNILGKQHDIRGTLMDQPKNGHQNYITKTQGVVAIKTMMTKLHTLQDYTRVREIKFILAIPANDHLIQIFEVFIDSE-------NYQLHIVME-CMEQNLYQMMKHRRRRVFSIPSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLAR------------HVENKNPYTAYVSTRWYRSPEILLRSGYYSKPLDIWAFGCV</Hsp_hseq>
      <Hsp_midline>+Y+L+ +LG GSFG V  A              +   P S  LG Q ++      +P  GH N +   + V+       ++    DY R             +  +++ E  +  E       +Y L +VME C   ++   +  R+   +   S    LS+ +A    +H ++  HRDLKP+NIL+  ++                 V+K+ADFGL++               N+   +    + +Y +PE+    G+++   DI+A G +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>79</Hit_num>
  <Hit_id>YNL183C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:293137:295509:-1 gene:YNL183C transcript:YNL183C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NPR1 description:Protein kinase; stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p; negatively regulates Ldb19p-mediated endocytosis through phosphorylation of Ldb19p, which prevents its association with the plasma membrane; Npr1p activity is negatively regulated via phosphorylation by the TOR complex; NPR1 has a paralog, PRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005127]</Hit_def>
  <Hit_accession>YNL183C</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>6.91418e-06</Hsp_evalue>
      <Hsp_query-from>599</Hsp_query-from>
      <Hsp_query-to>994</Hsp_query-to>
      <Hsp_hit-from>513</Hsp_hit-from>
      <Hsp_hit-to>635</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>134</Hsp_align-len>
      <Hsp_qseq>LWLVMEYCDGGDMNGYLLSRQPDHWLNTSFAMQLSRAVAFLHRNSIVHRDLKPDNILVAENSGRPVLKVADFGLSKIFAGQGQGLSSGESVNRAWLSPACGSSFYMAPEV--WEGHFTAKADIFALGIIVWAML</Hsp_qseq>
      <Hsp_hseq>ILQVMEYCEY-DLFAIVMSNKMSYEEICCCFKQILTGVQYLHSIGLAHRDLKLDNCVINE---KGIVKLIDFGAAVVF-------SYPFSKNLVEASGIVGSDPYLAPEVCIFAKYDPRPVDIWSSAIIFACMI</Hsp_hseq>
      <Hsp_midline>+  VMEYC+  D+   ++S +  +        Q+   V +LH   + HRDLK DN ++ E   + ++K+ DFG + +F       S   S N    S   GS  Y+APEV  +  +     DI++  II   M+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>105</Statistics_hsp-len>
      <Statistics_eff-space>4262227573</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0032173-RA transcript Note:&quot;Similar to TLL2 Tolloid-like protein 2 (Homo sapiens)&quot; offset:0 AED:0.35 eAED:0.37 QI:0|0|0|0.2|0.75|0.8|5|0|185</Iteration_query-def>
  <Iteration_query-len>558</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>84</Statistics_hsp-len>
      <Statistics_eff-space>240686034</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057502-RA transcript Note:&quot;Similar to Slc2a12 Solute carrier family 2, facilitated glucose transporter member 12 (Mus musculus)&quot; offset:486 AED:0.32 eAED:0.32 QI:486|0.57|0.5|0.87|1|1|8|0|450</Iteration_query-def>
  <Iteration_query-len>1839</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDR342C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1154216:1155928:-1 gene:YDR342C transcript:YDR342C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HXT7 description:High-affinity glucose transporter; member of the major facilitator superfamily, nearly identical to Hxt6p, expressed at high basal levels relative to other HXTs, expression repressed by high glucose levels; HXT7 has a paralog, HXT4, that arose from the whole genome duplication [Source:SGD;Acc:S000002750]</Hit_def>
  <Hit_accession>YDR342C</Hit_accession>
  <Hit_len>570</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>4.84368e-14</Hsp_evalue>
      <Hsp_query-from>805</Hsp_query-from>
      <Hsp_query-to>1293</Hsp_query-to>
      <Hsp_hit-from>192</Hsp_hit-from>
      <Hsp_hit-to>355</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>VAEVAHPRRRGALVSAYELGVTGGVLAAYAANLXXXXXXXXXXXXXAPWRWMFGLCCVPALAQV--MLLVACLPASPSSLLRCGQAEAAERTL----RRILGQQDVSAEIDALRSSLEMEK---QYSVLDLLRRKDSMRTRMLIGGGLVAFQQLTGQPTVLFYAASVFRAAG</Hsp_qseq>
      <Hsp_hseq>ISEVSPKHLRGTLVSCYQLMITAGIFLGYCTNFGTKNYSNS-----VQWRVPLGLCFAWALFMIGGMTFV---PESPRYLAEVGKIEEAKRSIAVSNKVAVDDPSVLAEVEAVLAGVEAEKLAGNASWGELFSSKTKVLQRLIMGAMIQSLQQLTGDNYFFYYGTTIFKAVG</Hsp_hseq>
      <Hsp_midline>++EV+    RG LVS Y+L +T G+   Y  N                WR   GLC   AL  +  M  V   P SP  L   G+ E A+R++    +  +    V AE++A+ + +E EK     S  +L   K  +  R+++G  + + QQLTG     +Y  ++F+A G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YHR096C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:294669:296447:-1 gene:YHR096C transcript:YHR096C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HXT5 description:Hexose transporter with moderate affinity for glucose; induced in the presence of non-fermentable carbon sources, induced by a decrease in growth rate, contains an extended N-terminal domain relative to other HXTs; HXT5 has a paralog, HXT3, that arose from the whole genome duplication [Source:SGD;Acc:S000001138]</Hit_def>
  <Hit_accession>YHR096C</Hit_accession>
  <Hit_len>592</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>4.94137e-14</Hsp_evalue>
      <Hsp_query-from>805</Hsp_query-from>
      <Hsp_query-to>1293</Hsp_query-to>
      <Hsp_hit-from>213</Hsp_hit-from>
      <Hsp_hit-to>376</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>170</Hsp_align-len>
      <Hsp_qseq>VAEVAHPRRRGALVSAYELGVTGGVLAAYAANLXXXXXXXXXXXXXAPWRWMFGLCCVPALAQVMLLVACLPASPSSLLRCGQAEAAERTLRRILGQQD----VSAEIDALRSSLEMEK---QYSVLDLLRRKDSMRTRMLIGGGLVAFQQLTGQPTVLFYAASVFRAAG</Hsp_qseq>
      <Hsp_hseq>ISEVSPKQLRGTLVSCYQLMITFGIFLGYCTNF-----GTKNYSNSVQWRVPLGLCFAWSIFMIVGMTF-VPESPRYLVEVGKIEEAKRSLARANKTTEDSPLVTLEMENYQSSIEAERLAGSASWGELVTGKPQMFRRTLMGMMIQSLQQLTGDNYFFYYGTTIFQAVG</Hsp_hseq>
      <Hsp_midline>++EV+  + RG LVS Y+L +T G+   Y  N                WR   GLC   ++  ++ +   +P SP  L+  G+ E A+R+L R     +    V+ E++  +SS+E E+     S  +L+  K  M  R L+G  + + QQLTG     +Y  ++F+A G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YDR343C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1159608:1161320:-1 gene:YDR343C transcript:YDR343C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HXT6 description:High-affinity glucose transporter; member of the major facilitator superfamily, nearly identical to Hxt7p, expressed at high basal levels relative to other HXTs, repression of expression by high glucose requires SNF3; HXT6 has a paralog, HXT1, that arose from the whole genome duplication [Source:SGD;Acc:S000002751]</Hit_def>
  <Hit_accession>YDR343C</Hit_accession>
  <Hit_len>570</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>5.14853e-14</Hsp_evalue>
      <Hsp_query-from>805</Hsp_query-from>
      <Hsp_query-to>1293</Hsp_query-to>
      <Hsp_hit-from>192</Hsp_hit-from>
      <Hsp_hit-to>355</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>VAEVAHPRRRGALVSAYELGVTGGVLAAYAANLXXXXXXXXXXXXXAPWRWMFGLCCVPALAQV--MLLVACLPASPSSLLRCGQAEAAERTL----RRILGQQDVSAEIDALRSSLEMEK---QYSVLDLLRRKDSMRTRMLIGGGLVAFQQLTGQPTVLFYAASVFRAAG</Hsp_qseq>
      <Hsp_hseq>ISEVSPKHLRGTLVSCYQLMITAGIFLGYCTNFGTKNYSNS-----VQWRVPLGLCFAWALFMIGGMTFV---PESPRYLAEVGKIEEAKRSIAVSNKVAVDDPSVLAEVEAVLAGVEAEKLAGNASWGELFSSKTKVLQRLIMGAMIQSLQQLTGDNYFFYYGTTIFKAVG</Hsp_hseq>
      <Hsp_midline>++EV+    RG LVS Y+L +T G+   Y  N                WR   GLC   AL  +  M  V   P SP  L   G+ E A+R++    +  +    V AE++A+ + +E EK     S  +L   K  +  R+++G  + + QQLTG     +Y  ++F+A G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YLR081W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:290212:291936:1 gene:YLR081W transcript:YLR081W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GAL2 description:Galactose permease; required for utilization of galactose; also able to transport glucose [Source:SGD;Acc:S000004071]</Hit_def>
  <Hit_accession>YLR081W</Hit_accession>
  <Hit_len>574</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.4034</Hsp_bit-score>
      <Hsp_score>176</Hsp_score>
      <Hsp_evalue>8.22937e-14</Hsp_evalue>
      <Hsp_query-from>805</Hsp_query-from>
      <Hsp_query-to>1293</Hsp_query-to>
      <Hsp_hit-from>198</Hsp_hit-from>
      <Hsp_hit-to>361</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>170</Hsp_align-len>
      <Hsp_qseq>VAEVAHPRRRGALVSAYELGVTGGVLAAYAANLXXXXXXXXXXXXXAPWRWMFGLCCVPALAQVMLLVACLPASPSSLLRCGQAEAAERTLRR--ILGQQD--VSAEIDALRSSLEMEK---QYSVLDLLRRKDSMRTRMLIGGGLVAFQQLTGQPTVLFYAASVFRAAG</Hsp_qseq>
      <Hsp_hseq>ISEIAPKHLRGTLVSCYQLMITAGIFLGYCTNY-----GTKSYSNSVQWRVPLGLCFAWSLFMIGAL-TLVPESPRYLCEVNKVEDAKRSIAKSNKVSPEDPAVQAELDLIMAGIEAEKLAGNASWGELFSTKTKVFQRLLMGVFVQMFQQLTGNNYFFYYGTVIFKSVG</Hsp_hseq>
      <Hsp_midline>++E+A    RG LVS Y+L +T G+   Y  N         +      WR   GLC   +L  +  L   +P SP  L    + E A+R++ +   +  +D  V AE+D + + +E EK     S  +L   K  +  R+L+G  +  FQQLTG     +Y   +F++ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YJL219W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:19497:21200:1 gene:YJL219W transcript:YJL219W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HXT9 description:Putative hexose transporter that is nearly identical to Hxt11p; has similarity to major facilitator superfamily (MFS) transporters, expression of HXT9 is regulated by transcription factors Pdr1p and Pdr3p [Source:SGD;Acc:S000003755]</Hit_def>
  <Hit_accession>YJL219W</Hit_accession>
  <Hit_len>567</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>9.76187e-14</Hsp_evalue>
      <Hsp_query-from>805</Hsp_query-from>
      <Hsp_query-to>1299</Hsp_query-to>
      <Hsp_hit-from>188</Hsp_hit-from>
      <Hsp_hit-to>353</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>178</Hsp_align-len>
      <Hsp_qseq>VAEVAHPRRRGALVSAYELGVTGGVLAAYAANLXXXXXXXXXXXXXAPWRWMFGLCCVPALAQVMLLVACL---PASPSSLLRCGQAEAAERTLRRILGQQDVS-------AEIDALRSSLEMEK---QYSVLDLLRRKDSMRTRMLIGGGLVAFQQLTGQPTVLFYAASVFRAAGYR</Hsp_qseq>
      <Hsp_hseq>ISEVAPKQIRGTLVQLYQLMCTMGIFLGYCTNY-----GTKNYHNATQWRVGLGLC----FAWTTFMVSGMMFVPESPRYLIEVGKDEEAKRSLSK---SNKVSVDDPALLAEYDTIKAGIELEKLAGNASWSELLSTKTKVFQRVLMGVMIQSLQQLTGDNYFFYYGTTIFKSVGLK</Hsp_hseq>
      <Hsp_midline>++EVA  + RG LV  Y+L  T G+   Y  N                WR   GLC     A    +V+ +   P SP  L+  G+ E A+R+L +      VS       AE D +++ +E+EK     S  +LL  K  +  R+L+G  + + QQLTG     +Y  ++F++ G +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YOL156W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:25273:26976:1 gene:YOL156W transcript:YOL156W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HXT11 description:Hexose transporter; capable of transporting a broad range of substrates including: glucose, fructose, mannose and galactose; polyol transporter that supports the growth on and uptake of xylitol with low affinity when overexpressed in a strain deleted for hexose family members; nearly identical in sequence to Hxt9p; has similarity to major facilitator superfamily (MFS) transporters; involved in pleiotropic drug resistance [Source:SGD;Acc:S000005516]</Hit_def>
  <Hit_accession>YOL156W</Hit_accession>
  <Hit_len>567</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.8626</Hsp_bit-score>
      <Hsp_score>172</Hsp_score>
      <Hsp_evalue>2.37431e-13</Hsp_evalue>
      <Hsp_query-from>805</Hsp_query-from>
      <Hsp_query-to>1299</Hsp_query-to>
      <Hsp_hit-from>188</Hsp_hit-from>
      <Hsp_hit-to>353</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>177</Hsp_align-len>
      <Hsp_qseq>VAEVAHPRRRGALVSAYELGVTGGVLAAYAANLXXXXXXXXXXXXXAPWRWMFGLCCVPALAQV--MLLVACLPASPSSLLRCGQAEAAERTLRRILGQQDVS-------AEIDALRSSLEMEK---QYSVLDLLRRKDSMRTRMLIGGGLVAFQQLTGQPTVLFYAASVFRAAGYR</Hsp_qseq>
      <Hsp_hseq>ISEVAPKHIRGTLVQLYQLMGTMGIFLGYCTNY-----GTKNYHNATQWRVGLGLCFAWATFMVSGMMFV---PESPRYLIEVGKDEEAKRSLSK---SNKVSVDDPALLVEYDTIKAGIELEKLAGNASWSELLSTKTKVFQRVLMGVMIQSLQQLTGDNYFFYYGTTIFKSVGLK</Hsp_hseq>
      <Hsp_midline>++EVA    RG LV  Y+L  T G+   Y  N                WR   GLC   A   V  M+ V   P SP  L+  G+ E A+R+L +      VS        E D +++ +E+EK     S  +LL  K  +  R+L+G  + + QQLTG     +Y  ++F++ G +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YHR092C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:287081:288811:-1 gene:YHR092C transcript:YHR092C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HXT4 description:High-affinity glucose transporter; member of the major facilitator superfamily, expression is induced by low levels of glucose and repressed by high levels of glucose; HXT4 has a paralog, HXT7, that arose from the whole genome duplication [Source:SGD;Acc:S000001134]</Hit_def>
  <Hit_accession>YHR092C</Hit_accession>
  <Hit_len>576</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>6.79479e-12</Hsp_evalue>
      <Hsp_query-from>805</Hsp_query-from>
      <Hsp_query-to>1293</Hsp_query-to>
      <Hsp_hit-from>198</Hsp_hit-from>
      <Hsp_hit-to>361</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>VAEVAHPRRRGALVSAYELGVTGGVLAAYAANLXXXXXXXXXXXXXAPWRWMFGLCCVPALAQV--MLLVACLPASPSSLLRCGQAEAAERT--LRRILGQQD--VSAEIDALRSSLEMEK---QYSVLDLLRRKDSMRTRMLIGGGLVAFQQLTGQPTVLFYAASVFRAAG</Hsp_qseq>
      <Hsp_hseq>ISEVSPKHIRGTLVSCYQLMITLGIFLGYCTNY-----GTKTYTNSVQWRVPLGLGFAWALFMIGGMTFV---PESPRYLVEVGKIEEAKRSIALSNKVSADDPAVMAEVEVVQATVEAEKLAGNASWGEIFSTKTKVFQRLIMGAMIQSLQQLTGDNYFFYYGTTVFTAVG</Hsp_hseq>
      <Hsp_midline>++EV+    RG LVS Y+L +T G+   Y  N         T      WR   GL    AL  +  M  V   P SP  L+  G+ E A+R+  L   +   D  V AE++ +++++E EK     S  ++   K  +  R+++G  + + QQLTG     +Y  +VF A G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YDR345C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1162957:1164660:-1 gene:YDR345C transcript:YDR345C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HXT3 description:Low affinity glucose transporter of the major facilitator superfamily; expression is induced in low or high glucose conditions; HXT3 has a paralog, HXT5, that arose from the whole genome duplication [Source:SGD;Acc:S000002753]</Hit_def>
  <Hit_accession>YDR345C</Hit_accession>
  <Hit_len>567</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>7.00423e-12</Hsp_evalue>
      <Hsp_query-from>805</Hsp_query-from>
      <Hsp_query-to>1293</Hsp_query-to>
      <Hsp_hit-from>189</Hsp_hit-from>
      <Hsp_hit-to>352</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>VAEVAHPRRRGALVSAYELGVTGGVLAAYAANLXXXXXXXXXXXXXAPWRWMFGLCCVPALAQV--MLLVACLPASPSSLLRCGQAEAAERTLRRIL----GQQDVSAEIDALRSSLEMEK---QYSVLDLLRRKDSMRTRMLIGGGLVAFQQLTGQPTVLFYAASVFRAAG</Hsp_qseq>
      <Hsp_hseq>ISEVAPKEMRGTLVSCYQLMITLGIFLGYCTNF-----GTKNYSNSVQWRVPLGLCFAWALFMIGGMTFV---PESPRYLVEAGQIDEARASLSKVNKVAPDHPFIQQELEVIEASVEEARAAGSASWGELFTGKPAMFKRTMMGIMIQSLQQLTGDNYFFYYGTTVFNAVG</Hsp_hseq>
      <Hsp_midline>++EVA    RG LVS Y+L +T G+   Y  N                WR   GLC   AL  +  M  V   P SP  L+  GQ + A  +L ++         +  E++ + +S+E  +     S  +L   K +M  R ++G  + + QQLTG     +Y  +VF A G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YEL069C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:21537:23231:-1 gene:YEL069C transcript:YEL069C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HXT13 description:Putative transmembrane polyol transporter; supports growth on and uptake of mannitol and sorbitol with moderate affinity when overexpressed in a strain deleted for hexose family members; minor hexose transport activity when overexpressed in a similar strain; induced by non-fermentable carbon sources; induced in low glucose, repressed in high glucose; HXT13 has a paralog, HXT17, that arose from a segmental duplication [Source:SGD;Acc:S000000795]</Hit_def>
  <Hit_accession>YEL069C</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>7.53088e-11</Hsp_evalue>
      <Hsp_query-from>805</Hsp_query-from>
      <Hsp_query-to>1293</Hsp_query-to>
      <Hsp_hit-from>185</Hsp_hit-from>
      <Hsp_hit-to>348</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>VAEVAHPRRRGALVSAYELGVTGGVLAAYAANLXXXXXXXXXXXXXAPWRWMFGLCCVPALAQV--MLLVACLPASPSSLLRCGQAEAAERTLRRI--LGQQD--VSAEIDALRSSLEMEKQY---SVLDLLRRKDSMRTRMLIGGGLVAFQQLTGQPTVLFYAASVFRAAG</Hsp_qseq>
      <Hsp_hseq>LSEIAPTDLRGGLVSLYQLNMTFGIFLGYCS-----VYGTRKYDNTAQWRVPLGLCFLWALIIIIGMLLV---PESPRYLIECERHEEARASIAKINKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFSVKTKVLQRLITGILVQTFLQLTGENYFFFYGTTIFKSVG</Hsp_hseq>
      <Hsp_midline>++E+A    RG LVS Y+L +T G+   Y +               A WR   GLC + AL  +  MLLV   P SP  L+ C + E A  ++ +I  +  +D  V  + D + + +  +++    S  +L   K  +  R++ G  +  F QLTG+    FY  ++F++ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YHR094C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:290913:292625:-1 gene:YHR094C transcript:YHR094C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HXT1 description:Low-affinity glucose transporter of the major facilitator superfamily; expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting; HXT1 has a paralog, HXT6, what arose from the whole genome duplication [Source:SGD;Acc:S000001136]</Hit_def>
  <Hit_accession>YHR094C</Hit_accession>
  <Hit_len>570</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>1.22324e-10</Hsp_evalue>
      <Hsp_query-from>805</Hsp_query-from>
      <Hsp_query-to>1293</Hsp_query-to>
      <Hsp_hit-from>192</Hsp_hit-from>
      <Hsp_hit-to>355</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>VAEVAHPRRRGALVSAYELGVTGGVLAAYAANLXXXXXXXXXXXXXAPWRWMFGLCCVPALAQV--MLLVACLPASPSSLLRCGQAEAAERTLRRIL----GQQDVSAEIDALRSSLEMEKQYSVL---DLLRRKDSMRTRMLIGGGLVAFQQLTGQPTVLFYAASVFRAAG</Hsp_qseq>
      <Hsp_hseq>ISEVAPSEMRGTLVSCYQVMITLGIFLGYCTNF-----GTKNYSNSVQWRVPLGLCFAWALFMIGGMMFV---PESPRYLVEAGRIDEARASLAKVNKCPPDHPYIQYELETIEASVEEMRAAGTASWGELFTGKPAMFQRTMMGIMIQSLQQLTGDNYFFYYGTIVFQAVG</Hsp_hseq>
      <Hsp_midline>++EVA    RG LVS Y++ +T G+   Y  N                WR   GLC   AL  +  M+ V   P SP  L+  G+ + A  +L ++         +  E++ + +S+E  +        +L   K +M  R ++G  + + QQLTG     +Y   VF+A G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YNR072W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:772657:774351:1 gene:YNR072W transcript:YNR072W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HXT17 description:Putative transmembrane polyol transporter; supports growth on and uptake of mannitol and sorbitol with moderate affinity when overexpressed in a strain deleted for hexose family members; minor hexose transport activity when overexpressed in a similar strain; induced by raffinose and galactose at pH 7.7 versus pH 4.7, repressed by high levels of glucose; HXT17 has a paralog, HXT13, that arose from a segmental duplication [Source:SGD;Acc:S000005355]</Hit_def>
  <Hit_accession>YNR072W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>1.92195e-10</Hsp_evalue>
      <Hsp_query-from>805</Hsp_query-from>
      <Hsp_query-to>1293</Hsp_query-to>
      <Hsp_hit-from>185</Hsp_hit-from>
      <Hsp_hit-to>348</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>VAEVAHPRRRGALVSAYELGVTGGVLAAYAANLXXXXXXXXXXXXXAPWRWMFGLCCVPALAQV--MLLVACLPASPSSLLRCGQAEAAERTLRRI--LGQQD--VSAEIDALRSSLEMEKQY---SVLDLLRRKDSMRTRMLIGGGLVAFQQLTGQPTVLFYAASVFRAAG</Hsp_qseq>
      <Hsp_hseq>LSEIAPTDLRGGLVSLYQLNMTFGIFLGYCS-----VYGTRKYDNTAQWRVPLGLCFLWTLIIIIGMLLV---PESPRYLIECERHEEARASIAKINKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFSVKTKVLQRLITGILVQTFLQLTGENYFFFYGTTIFKSVG</Hsp_hseq>
      <Hsp_midline>++E+A    RG LVS Y+L +T G+   Y +               A WR   GLC +  L  +  MLLV   P SP  L+ C + E A  ++ +I  +  +D  V  + D + + +  +++    S  +L   K  +  R++ G  +  F QLTG+    FY  ++F++ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YJR158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:732440:734143:1 gene:YJR158W transcript:YJR158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HXT16 description:Putative transmembrane polyol transporter; supports growth on and uptake of sorbitol with moderate affinity and mannitol with lower affinity when overexpressed in a strain deleted for hexose family members; minor hexose transport activity when overexpressed in a similar strain; similarity to hexose transporters; expression is repressed by high levels of glucose [Source:SGD;Acc:S000003919]</Hit_def>
  <Hit_accession>YJR158W</Hit_accession>
  <Hit_len>567</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>2.77699e-10</Hsp_evalue>
      <Hsp_query-from>805</Hsp_query-from>
      <Hsp_query-to>1293</Hsp_query-to>
      <Hsp_hit-from>188</Hsp_hit-from>
      <Hsp_hit-to>351</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>VAEVAHPRRRGALVSAYELGVTGGVLAAYAANLXXXXXXXXXXXXXAPWRWMFGLCCVPALAQV--MLLVACLPASPSSLLRCGQAEAAERTLRRI--LGQQD--VSAEIDALRSSLEMEKQY---SVLDLLRRKDSMRTRMLIGGGLVAFQQLTGQPTVLFYAASVFRAAG</Hsp_qseq>
      <Hsp_hseq>LSEIAPTDLRGGLVSLYQLNMTFGIFLGYCS-----VYGTRKYSNTAQWRIPVGLCFLWALIIIVGMLLV---PESPRYLIECERHEEACVSIAKIDKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFSVKTKVLQRLITGILVQTFLQLTGENYFFFYGTTIFKSVG</Hsp_hseq>
      <Hsp_midline>++E+A    RG LVS Y+L +T G+   Y +               A WR   GLC + AL  +  MLLV   P SP  L+ C + E A  ++ +I  +  +D  V  + D + + +  +++    S  +L   K  +  R++ G  +  F QLTG+    FY  ++F++ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YDL245C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:11657:13360:-1 gene:YDL245C transcript:YDL245C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HXT15 description:Putative transmembrane polyol transporter; supports growth on and uptake of mannitol, sorbitol and xylitol with moderate affinity when overexpressed in a strain deleted for hexose family members; minor hexose transport activity when overexpressed in a similar strain; similarity to hexose transporters; expression is induced by low levels of glucose and repressed by high levels of glucose [Source:SGD;Acc:S000002404]</Hit_def>
  <Hit_accession>YDL245C</Hit_accession>
  <Hit_len>567</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>2.95072e-10</Hsp_evalue>
      <Hsp_query-from>805</Hsp_query-from>
      <Hsp_query-to>1293</Hsp_query-to>
      <Hsp_hit-from>188</Hsp_hit-from>
      <Hsp_hit-to>351</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>VAEVAHPRRRGALVSAYELGVTGGVLAAYAANLXXXXXXXXXXXXXAPWRWMFGLCCVPALAQV--MLLVACLPASPSSLLRCGQAEAAERTLRRI--LGQQD--VSAEIDALRSSLEMEKQY---SVLDLLRRKDSMRTRMLIGGGLVAFQQLTGQPTVLFYAASVFRAAG</Hsp_qseq>
      <Hsp_hseq>LSEIAPTDLRGGLVSLYQLNMTFGIFLGYCS-----VYGTRKYSNTAQWRIPVGLCFLWALIIIVGMLLV---PESPRYLIECERHEEACVSIAKINKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFSVKTKVLQRLITGILVQTFLQLTGENYFFFYGTTIFKSVG</Hsp_hseq>
      <Hsp_midline>++E+A    RG LVS Y+L +T G+   Y +               A WR   GLC + AL  +  MLLV   P SP  L+ C + E A  ++ +I  +  +D  V  + D + + +  +++    S  +L   K  +  R++ G  +  F QLTG+    FY  ++F++ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YOL103W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:124001:125830:1 gene:YOL103W transcript:YOL103W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ITR2 description:Myo-inositol transporter; member of the sugar transporter superfamily; expressed constitutively; ITR2 has a paralog, ITR1, that arose from the whole genome duplication [Source:SGD;Acc:S000005463]</Hit_def>
  <Hit_accession>YOL103W</Hit_accession>
  <Hit_len>609</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>1.42375e-08</Hsp_evalue>
      <Hsp_query-from>799</Hsp_query-from>
      <Hsp_query-to>1302</Hsp_query-to>
      <Hsp_hit-from>225</Hsp_hit-from>
      <Hsp_hit-to>394</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>180</Hsp_align-len>
      <Hsp_qseq>VYVAEVAHPRRRGALVSAYELGVTGGVLAAYAANLXXXXXXXXXXXXXAPWRWMFGLCCVPALAQVMLLVACLPASPSSLLRCGQAEAAERTLRR--------ILGQQDVSAEIDALRSSL----EMEKQYSVLDLLRRKDSMRTRMLIGGGLVAFQQLTGQPTVLFYAASVFRAAGYRG</Hsp_qseq>
      <Hsp_hseq>LFISEIAPKMIRGRLTVINSLWLTGGQLIAYGCG-------AGLNHVKNGWRILVGLSLIPTVLQFSFF-CFLPDTPRYYVMKGDLKRAKMVLKRSYVNTEDEIIDQK--VEELSSLNQSIPGKNPITKFWNMVKELHTVPSNFRALIIGCGLQAIQQFTGWNSLMYFSGTIFETVGFKN</Hsp_hseq>
      <Hsp_midline>++++E+A    RG L     L +TGG L AY           G       WR + GL  +P + Q       LP +P   +  G  + A+  L+R        I+ Q+    E+ +L  S+     + K ++++  L    S    ++IG GL A QQ TG  ++++++ ++F   G++ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YDR497C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1443713:1445467:-1 gene:YDR497C transcript:YDR497C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ITR1 description:Myo-inositol transporter; member of the sugar transporter superfamily; expression is repressed by inositol and choline via Opi1p and derepressed via Ino2p and Ino4p; relative distribution to the vacuole increases upon DNA replication stress; ITR1 has a paralog, ITR2, that arose from the whole genome duplication [Source:SGD;Acc:S000002905]</Hit_def>
  <Hit_accession>YDR497C</Hit_accession>
  <Hit_len>584</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>2.50332e-08</Hsp_evalue>
      <Hsp_query-from>799</Hsp_query-from>
      <Hsp_query-to>1302</Hsp_query-to>
      <Hsp_hit-from>202</Hsp_hit-from>
      <Hsp_hit-to>371</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>181</Hsp_align-len>
      <Hsp_qseq>VYVAEVAHPRRRGALVSAYELGVTGGVLAAYAANLXXXXXXXXXXXXXAPWRWMFGLCCVPALAQVMLLVACLPASPSSLLRCGQAEAAERTLRRILGQQDVSAEIDALRSSLEM-------------EKQYSVLDLLRRKDSMRTRMLIGGGLVAFQQLTGQPTVLFYAASVFRAAGYRG</Hsp_qseq>
      <Hsp_hseq>LFISEIAPKMIRGRLTVINSLWLTGGQLVAYGCG-------AGLNYVNNGWRILVGLSLIPTAVQFTCL-CFLPDTPRYYVMKGDLARATEVLKR--SYTDTSEEIIE-RKVEELVTLNQSIPGKNVPEKVWNTIKELHTVPSNLRALIIGCGLQAIQQFTGWNSLMYFSGTIFETVGFKN</Hsp_hseq>
      <Hsp_midline>++++E+A    RG L     L +TGG L AY           G       WR + GL  +P   Q   L   LP +P   +  G    A   L+R     D S EI   R   E+             EK ++ +  L    S    ++IG GL A QQ TG  ++++++ ++F   G++ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1184700706</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057504-RA transcript Note:&quot;Similar to Tpo Thyroid peroxidase (Rattus norvegicus)&quot; offset:0 AED:0.29 eAED:0.29 QI:0|0.44|0.5|1|1|1|10|0|649</Iteration_query-def>
  <Iteration_query-len>1950</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1263378718</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057505-RA transcript Note:&quot;Similar to otof Otoferlin (Danio rerio)&quot; offset:0 AED:0.20 eAED:0.21 QI:0|0.12|0.09|0.87|1|1|32|1121|1356</Iteration_query-def>
  <Iteration_query-len>5192</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3635152409</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057507-RA transcript Note:&quot;Similar to Plec Plectin (Mus musculus)&quot; offset:0 AED:0.17 eAED:0.17 QI:0|0.38|0.46|0.81|1|1|32|0|3544</Iteration_query-def>
  <Iteration_query-len>10635</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDR129C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:713340:715379:-1 gene:YDR129C transcript:YDR129C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAC6 description:Fimbrin, actin-bundling protein; cooperates with Scp1p in organization and maintenance of the actin cytoskeleton; phosphorylated by Cdc28p/Clb2p in metaphase on T103, to regulate conformation, and modulate actin filament binding affinity and actin cable dynamics; relocalizes from the plasma membrane to the cytoplasm upon DNA replication stress; human homologs PLS3 and LCP1 implicated in spinocerebellar ataxia type 2 (SCA2) can each complement yeast null mutant [Source:SGD;Acc:S000002536]</Hit_def>
  <Hit_accession>YDR129C</Hit_accession>
  <Hit_len>642</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>1.76371e-09</Hsp_evalue>
      <Hsp_query-from>247</Hsp_query-from>
      <Hsp_query-to>891</Hsp_query-to>
      <Hsp_hit-from>413</Hsp_hit-from>
      <Hsp_hit-to>637</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>234</Hsp_align-len>
      <Hsp_qseq>QKKTFTKWVNKHLMKVRKHVNDMYEDLRDGHNLISLLE-VLSG-------EKLPREKGRM-RFHRLHNVQIALDFLRLRQIKLVNIRSDDIADGNPKLTLGLIWTII-LHFQIADIQVSGQSEDMTAKDRLLLWSQRMVEGYPGIRCDNFTTSWRDGRLFNA-----IIHRHRPELIDMKRVAVRANRE----NLEQAFTVAERDMGVTRLLXXXXXXXXXXXXKSIITYVSSL</Hsp_qseq>
      <Hsp_hseq>EARVFTLWLNS--LDVDPPVISLFDDLKDGLILLQAYEKVMPGAVDFKHVNKRPASGAEISRFKALENTNYAVDLGRAKGFSLVGIEGSDIVDGNKLLTLGLVWQLMRRNISITMKTLSSSGRDMS-DSQILKWAQDQVT--KGGK-NSTIRSFKDQALSNAHFLLDVLNGIAPGYVDYDLVTPGNTEEERYANARLAISIA-RKLGA--LIWLVPEDINEVRARLIITFIASL</Hsp_hseq>
      <Hsp_midline>+ + FT W+N   + V   V  +++DL+DG  L+   E V+ G        K P     + RF  L N   A+D  R +   LV I   DI DGN  LTLGL+W ++  +  I    +S    DM+   ++L W+Q  V    G + ++   S++D  L NA     +++   P  +D   V      E    N   A ++A R +G   L+     D+     + IIT+++SL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>109</Statistics_hsp-len>
      <Statistics_eff-space>7540875812</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057523-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.09 eAED:0.11 QI:0|0|0|0.33|1|1|3|0|160</Iteration_query-def>
  <Iteration_query-len>483</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>82</Statistics_hsp-len>
      <Statistics_eff-space>187456493</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057527-RA transcript Note:&quot;Similar to Collagen alpha-2(IV) chain (Ascaris suum)&quot; offset:0 AED:0.09 eAED:0.54 QI:0|0|0|0.57|1|1|7|0|1099</Iteration_query-def>
  <Iteration_query-len>3300</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2254067000</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0040871-RA transcript Note:&quot;Similar to Csmd1 CUB and sushi domain-containing protein 1 (Mus musculus)&quot; offset:0 AED:0.19 eAED:0.20 QI:0|0|0|0.85|0.16|0.14|7|77|251</Iteration_query-def>
  <Iteration_query-len>833</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>88</Statistics_hsp-len>
      <Statistics_eff-space>440987463</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057519-RA transcript Note:&quot;Similar to Csmd3 CUB and sushi domain-containing protein 3 (Mus musculus)&quot; offset:0 AED:0.05 eAED:0.05 QI:0|0|0|1|1|1|2|0|119</Iteration_query-def>
  <Iteration_query-len>360</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>78</Statistics_hsp-len>
      <Statistics_eff-space>100769214</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057520-RA transcript Note:&quot;Similar to Csmd3 CUB and sushi domain-containing protein 3 (Mus musculus)&quot; offset:0 AED:0.24 eAED:0.25 QI:0|0|0|1|1|0.8|5|0|272</Iteration_query-def>
  <Iteration_query-len>819</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>88</Statistics_hsp-len>
      <Statistics_eff-space>431654395</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057521-RA transcript Note:&quot;Similar to Csmd1 CUB and sushi domain-containing protein 1 (Mus musculus)&quot; offset:0 AED:0.39 eAED:0.39 QI:0|0|0|1|1|0.66|3|0|270</Iteration_query-def>
  <Iteration_query-len>813</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>88</Statistics_hsp-len>
      <Statistics_eff-space>426987861</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

