<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0043076-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.36 eAED:0.83 QI:0|0|0.5|1|0|0|4|0|528</BlastOutput_query-def>
  <BlastOutput_query-len>1587</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0043076-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.36 eAED:0.83 QI:0|0|0.5|1|0|0|4|0|528</Iteration_query-def>
  <Iteration_query-len>1587</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>997745145</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054882-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.56 eAED:0.56 QI:0|0|0|0.5|1|1|2|0|73</Iteration_query-def>
  <Iteration_query-len>222</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>46</Statistics_hsp-len>
      <Statistics_eff-space>73093076</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054883-RA transcript Note:&quot;Similar to Ints5 Integrator complex subunit 5 (Mus musculus)&quot; offset:0 AED:0.36 eAED:0.37 QI:0|0.39|0.44|0.72|1|1|29|558|1928</Iteration_query-def>
  <Iteration_query-len>6345</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YPR033C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:637379:639019:-1 gene:YPR033C transcript:YPR033C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HTS1 description:Cytoplasmic and mitochondrial histidine tRNA synthetase; efficient mitochondrial localization requires both a presequence and an amino-terminal sequence; mutations in human ortholog HARS2 are associated with Perrault syndrome [Source:SGD;Acc:S000006237]</Hit_def>
  <Hit_accession>YPR033C</Hit_accession>
  <Hit_len>546</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.5153</Hsp_bit-score>
      <Hsp_score>236</Hsp_score>
      <Hsp_evalue>2.65464e-20</Hsp_evalue>
      <Hsp_query-from>2143</Hsp_query-from>
      <Hsp_query-to>3063</Hsp_query-to>
      <Hsp_hit-from>132</Hsp_hit-from>
      <Hsp_hit-to>464</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>82</Hsp_identity>
      <Hsp_positive>148</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>336</Hsp_align-len>
      <Hsp_qseq>VPFARFVARNNVTNLKRYCVERVFRPRK--LHRAHPRELIECAFDIVTSAGGCLPDAEIIYTTSEIIQEFPDRNYCVHLNHTALIKAILIHCGIPEDKHHQVYGILCDTMNEKRTKQQIMASLCSLGLHPDTVTLLFHFVERRGNRMDVLAALRPLAGKHSKTVGLVKQGLSYLEEVMKHLEYMCIRHQVVISLGLVYKVQLHSGLIFQF----------TSFVRRKNKTVLDI--------LAAGGRYDNLISMFRXXXXXXXXXXX-XXXXLALDKITSAILSKEDPPSF---NLCDVLVGAVGDAMR-----PRACSLVKDMWAAGLRAGVHY</Hsp_qseq>
      <Hsp_hseq>VPFARYVAMNNIQSIKRYHIAKVYRRDQPAMTKGRMREFYQCDFDVAGTFESMVPDSECLSILVEGLTSLGIKDFKIKLNHRKILDGIFQIAGVKDEDVRKISSAV-DKLDKSPWEAVKKEMTEEKGQSEETADKIGEYVKLNGSLKEIHAVLSADANITSNEK--AKQGLDDIATLMKYTEAFDIDSFISFDLSLARGLDYYTGLIYEVVTSASAPPENASELKKKAKSAEDASEFVGVGSIAAGGRYDNLVNMFSEASGKKSTQIPCVGISFGVERIFSLIKQRINSSTTIKPTATQVFVMAFGGGKDWTGYLPERMKVTKQLWDAGIEAEYVY</Hsp_hseq>
      <Hsp_midline>VPFAR+VA NN+ ++KRY + +V+R  +  + +   RE  +C FD+  +    +PD+E +    E +     +++ + LNH  ++  I    G+ ++   ++   + D +++   +          G   +T   +  +V+  G+  ++ A L   A   S      KQGL  +  +MK+ E   I   +   L L   +  ++GLI++            S +++K K+  D         +AAGGRYDNL++MF             VG+S  +++I S I  + +  +        V V A G         P    + K +W AG+ A   Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>4.67636e-12</Hsp_evalue>
      <Hsp_query-from>1888</Hsp_query-from>
      <Hsp_query-to>2064</Hsp_query-to>
      <Hsp_hit-from>880</Hsp_hit-from>
      <Hsp_hit-to>936</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>43</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>59</Hsp_align-len>
      <Hsp_qseq>GLTGQIGTALYVSPEVLGNIKAVYNQKVDLYSLGIIFFEMTYHPMTTASERVAVLQKLR</Hsp_qseq>
      <Hsp_hseq>NLTSAIGTAMYVATEVLDGT-GHYNEKIDMYSLGIIFFEMIY-PFSTGMERVNILKKLR</Hsp_hseq>
      <Hsp_midline> LT  IGTA+YV+ EVL      YN+K+D+YSLGIIFFEM Y P +T  ERV +L+KLR</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>1.58516e-11</Hsp_evalue>
      <Hsp_query-from>2146</Hsp_query-from>
      <Hsp_query-to>2850</Hsp_query-to>
      <Hsp_hit-from>1097</Hsp_hit-from>
      <Hsp_hit-to>1333</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>249</Hsp_align-len>
      <Hsp_qseq>PFARFVARNNVTNLKRYCVERVFRPRKLHRA--HPRELIECAFDIVT--SAGGCLPDAEIIYTTSEIIQEFP---DRNYCVHLNHTALIKAILIHCGIPEDKHHQVYGILCD-----TMNEKRTKQQIMASLCSLGLHPDTVTLLFHFVERRGNRMDVLAALRPLAG--KHSKTVGLVKQGLSYLEEVMKHLEYMCIRHQVVISLGLVYKVQLHSGLIFQFTSFVRRKNKTVLDILAAGGRYDNLISMF</Hsp_qseq>
      <Hsp_hseq>PMARYLSKNPSLISKQYRMQHVYRPPDHSRSSLEPRKFGEIDFDIISKSSSESGFYDAESLKIIDEILTVFPVFEKTNTFFILNHADILESVFNFTNIDKAQRPLVSRMLSQVGFARSFKEVKNELKAQLNISSTALND---LELFDF------RLDFEAAKKRLYKLMIDSPHLKKIEDSLSHISKVLSYLKPLEVARNVVISPLSNYNSAFYKGGIMFHAVY---DDGSSRNMIAAGGRYDTLISFF</Hsp_hseq>
      <Hsp_midline>P AR++++N     K+Y ++ V+RP    R+   PR+  E  FDI++  S+     DAE +    EI+  FP     N    LNH  +++++     I + +   V  +L       +  E + + +   ++ S  L+      LF F      R+D  AA + L      S  +  ++  LS++ +V+ +L+ + +   VVIS    Y    + G I     +    + +  +++AAGGRYD LIS F</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>4.86095e-06</Hsp_evalue>
      <Hsp_query-from>1162</Hsp_query-from>
      <Hsp_query-to>1338</Hsp_query-to>
      <Hsp_hit-from>608</Hsp_hit-from>
      <Hsp_hit-to>664</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>25</Hsp_identity>
      <Hsp_positive>35</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>59</Hsp_align-len>
      <Hsp_qseq>GVLLEQLAVKNKLDGCYYALKRIAVNPTSRQFRRIKGEVTLLSRLNHENIVRYYNAWIE</Hsp_qseq>
      <Hsp_hseq>GAFGQVVKARNALDSRYYAIKKI--RHTEEKLSTILSEVMLLASLNHQYVVRYYAAWLE</Hsp_hseq>
      <Hsp_midline>G   + +  +N LD  YYA+K+I    T  +   I  EV LL+ LNH+ +VRYY AW+E</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>4</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>5.75189e-06</Hsp_evalue>
      <Hsp_query-from>64</Hsp_query-from>
      <Hsp_query-to>399</Hsp_query-to>
      <Hsp_hit-from>6</Hsp_hit-from>
      <Hsp_hit-to>122</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>117</Hsp_align-len>
      <Hsp_qseq>LEQDSYEDRQENELEVLTAIYGSELTDL-RKQDPW----KVCISLAPHDSTGSACYVTVDLTVSCPPRYPDELPEIELNNAKGLSNESVKELQAQLTTLVSELRGEVMIFQLAHHVK</Hsp_qseq>
      <Hsp_hseq>LTLDQYYEIQCNELEAIRSIYMDDFTDLTKRKSSWDKQPQIIFEITLRSVDKEPVESSITLHFAMTPMYPYTAPEIEFKNVQNVMDSQLQMLKSEFKKIHNTSRGQEIIFEITSFTQ</Hsp_hseq>
      <Hsp_midline>L  D Y + Q NELE + +IY  + TDL +++  W    ++   +            ++ L  +  P YP   PEIE  N + + +  ++ L+++   + +  RG+ +IF++    +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>1.60855e-10</Hsp_evalue>
      <Hsp_query-from>514</Hsp_query-from>
      <Hsp_query-to>1185</Hsp_query-to>
      <Hsp_hit-from>1036</Hsp_hit-from>
      <Hsp_hit-to>1246</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>230</Hsp_align-len>
      <Hsp_qseq>ERSVYRGKCIGESTHLRRQVFNALDNSTGELVVVYEWVLRWPVGHPDLRTSEDKEHMEKCRKQSLLKLRHEALVPYLGMESQETETALTVHLLAEHVSGTSLAGHLARTGPLPVETVRQ-YASQLLHVLDYLHASSVVHRDLRLSSVLLDCATGLLRVADYSLARRLADA---CVASEQPGRPGVPRVHFVEPECGPXXXXXXXRSQPPKTGKKG--DVWRLGVLLEQLA</Hsp_qseq>
      <Hsp_hseq>KRSFIGGGTFG-------QVYSAINLENGEILAVKE------IKIHDTTTMKKIFPLIKEEMTVLEMLNHPNIVQYYGVEVHRDK----VNIFMEYCEGGSLASLLDH-GRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDF-NGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMA</Hsp_hseq>
      <Hsp_midline>+RS   G   G       QV++A++   GE++ V E      +   D  T +    + K     L  L H  +V Y G+E    +    V++  E+  G SLA  L   G +  E V Q Y  +LL  L YLH S VVHRD++  ++LLD   G+++  D+  AR +  +    V +      GV      E    P   A    S     GK G  DVW LG ++ ++A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>1.7757e-10</Hsp_evalue>
      <Hsp_query-from>640</Hsp_query-from>
      <Hsp_query-to>1191</Hsp_query-to>
      <Hsp_hit-from>484</Hsp_hit-from>
      <Hsp_hit-to>654</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>188</Hsp_align-len>
      <Hsp_qseq>VGHPDLRTSEDKEHMEKCRKQ-SLLK-LRHEALVPYLGMESQETETALTVHLLAEHVSGTSLAGHLARTGPLPVETVRQYASQLLHVLDYLHASSVVHRDLRLSSVLLDCATGLLRVADYSLARRLADACVASEQPGRPGVP-RVHFVEPECGPXXXXXXXRSQPPKTGKKGDVWRLG-VLLEQLAVK</Hsp_qseq>
      <Hsp_hseq>VSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGA-SQE---GGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIK-GCVKITDFGISKKLSP--LNKKQNKRASLQGSVFWMSPEV----------VKQTATTAKADIWSTGCVVIEMFTGK</Hsp_hseq>
      <Hsp_midline>V HP    +  ++ ++  + + +LLK L HE +V Y G  SQE      +++  E+V G S++  L   GP     +  +  Q+L  + YLH  +++HRD++ +++L+D   G +++ D+ ++++L+   +  +Q  R  +   V ++ PE            +   T  K D+W  G V++E    K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>3.31724e-10</Hsp_evalue>
      <Hsp_query-from>529</Hsp_query-from>
      <Hsp_query-to>1191</Hsp_query-to>
      <Hsp_hit-from>1177</Hsp_hit-from>
      <Hsp_hit-to>1377</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>226</Hsp_align-len>
      <Hsp_qseq>RGKCIGESTHLRRQVFNALDNSTGELVVVYEWVLRWPVGHPDLRTSEDK--EHMEKCRKQ--SLLKLRHEALVPYLGMESQETETALTVHLLAEHVSGTSLAGHLARTGPLPVETVRQYASQLLHVLDYLHASSVVHRDLRLSSVLLDCATGLLRVADYSLARRLADACVASEQPGRPGVPRVHFVEPECGPXXXXXXXRSQPPKTGKKGDVWRLG-VLLEQLAVK</Hsp_qseq>
      <Hsp_hseq>KGEMIGKGSF--GAVYLCLNVTTGEMMAVKQ------VEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNN----IYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLD-QDGICKISDFGISRKSKDIYSNSDMTMR-GT--VFWMAPEMVDTKQGYSA---------KVDIWSLGCIVLEMFAGK</Hsp_hseq>
      <Hsp_midline>+G+ IG+ +     V+  L+ +TGE++ V +      V  P   +  +     +E  R +  +L  L H  +V YLG E++         L  E+V+G S+   +   G      ++   +Q+L  L YLH+  ++HRD++  ++LLD   G+ +++D+ ++R+  D    S+   R G   V ++ PE        +A         K D+W LG ++LE  A K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>3.3347e-10</Hsp_evalue>
      <Hsp_query-from>541</Hsp_query-from>
      <Hsp_query-to>1017</Hsp_query-to>
      <Hsp_hit-from>1272</Hsp_hit-from>
      <Hsp_hit-to>1417</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>IGESTHLRRQVFNALDNSTGELVVVYEWVLRWPVGHPDLRTSEDKEHMEKCRKQSLLKLRHEALVPYLGMESQETETALTVHLLAEHVSGTSLAGHLARTGPLPVETVRQ-YASQLLHVLDYLHASSVVHRDLRLSSVLLDCATGLLRVADYSLARRLAD</Hsp_qseq>
      <Hsp_hseq>IGGGTFGR--VYSAVDLDNGEILAVKE------INIQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGVEVHRDK----VNIFMEYCEGGSLAA-LLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDF-NGVIKYVDFGAAKKIAN</Hsp_hseq>
      <Hsp_midline>IG  T  R  V++A+D   GE++ V E      +   D ++ +    + K     L  L H  +V Y G+E    +    V++  E+  G SLA  L   G +  E V Q Y  QLL  L YLH S +VHRD++  ++LLD   G+++  D+  A+++A+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>7.54896e-10</Hsp_evalue>
      <Hsp_query-from>781</Hsp_query-from>
      <Hsp_query-to>1173</Hsp_query-to>
      <Hsp_hit-from>198</Hsp_hit-from>
      <Hsp_hit-to>313</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>137</Hsp_align-len>
      <Hsp_qseq>VHLLAEHVSGTSLAGHLARTGPLPVETVRQYASQLLHVLDYLHASSVVHRDLRLSSVLLDCATGLLRVADYSLA------RRLADACVASEQPGRPGVPRVHFVEPECGPXXXXXXXRSQPPKTGKKGDVWRLGVLL</Hsp_qseq>
      <Hsp_hseq>FYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMI-SSSGEIKIIDFGLSNIFDYRKQLHTFCGS-----------LYFAAPEL--------LKAQ-PYTGPEVDIWSFGIVL</Hsp_hseq>
      <Hsp_midline> ++L E+VSG  L  ++ + G L     R++A  +   L YLHA+++VHRDL++ ++++  ++G +++ D+ L+      ++L   C +           ++F  PE          ++Q P TG + D+W  G++L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>3.0095e-08</Hsp_evalue>
      <Hsp_query-from>781</Hsp_query-from>
      <Hsp_query-to>1173</Hsp_query-to>
      <Hsp_hit-from>219</Hsp_hit-from>
      <Hsp_hit-to>334</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>137</Hsp_align-len>
      <Hsp_qseq>VHLLAEHVSGTSLAGHLARTGPLPVETVRQYASQLLHVLDYLHASSVVHRDLRLSSVLLDCATGLLRVADYSLA------RRLADACVASEQPGRPGVPRVHFVEPECGPXXXXXXXRSQPPKTGKKGDVWRLGVLL</Hsp_qseq>
      <Hsp_hseq>FYMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSE-IKIIDFGLSNIYDSRKQLHTFCGS-----------LYFAAPELLKAN---------PYTGPEVDVWSFGVVL</Hsp_hseq>
      <Hsp_midline> ++L E+VSG  L  ++ + G +     R++A  +   L YLHA+++VHRDL++ ++++  ++  +++ D+ L+      ++L   C +           ++F  PE              P TG + DVW  GV+L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>3.42034e-08</Hsp_evalue>
      <Hsp_query-from>766</Hsp_query-from>
      <Hsp_query-to>1173</Hsp_query-to>
      <Hsp_hit-from>97</Hsp_hit-from>
      <Hsp_hit-to>217</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>ETALTVHLLAEHVSGTSLAGHLARTGPLPVETVRQYASQLLHVLDYLHASSVVHRDLRLSSVLLDCATGLLRVADYSLARRLADACVASEQPGRPGVPRVHFVEPECGPXXXXXXXRSQPPKTGKKGDVWRLGVLL</Hsp_qseq>
      <Hsp_hseq>ETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYN-IKIADFGMAALQTDADLLETSCGSP-----HYAAPEI---------VSGLPYEGFASDVWSCGVIL</Hsp_hseq>
      <Hsp_midline>ET   ++L+ E+     L   L   GPLP         Q++  + Y HA  +VHRDL+  ++LLD     +++AD+ +A    DA +     G P     H+  PE           S  P  G   DVW  GV+L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>6.95198e-08</Hsp_evalue>
      <Hsp_query-from>766</Hsp_query-from>
      <Hsp_query-to>1173</Hsp_query-to>
      <Hsp_hit-from>101</Hsp_hit-from>
      <Hsp_hit-to>221</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>ETALTVHLLAEHVSGTSLAGHLARTGPLPVETVRQYASQLLHVLDYLHASSVVHRDLRLSSVLLDCATGLLRVADYSLARRLADACVASEQPGRPGVPRVHFVEPECGPXXXXXXXRSQPPKTGKKGDVWRLGVLL</Hsp_qseq>
      <Hsp_hseq>ETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYN-IKIADFGMAALETEGKLLETSCGSP-----HYAAPEIV---------SGIPYQGFASDVWSCGVIL</Hsp_hseq>
      <Hsp_midline>ET   ++L+ E+     L   L   GPLP     ++  Q++  + Y HA  +VHRDL+  ++LLD     +++AD+ +A    +  +     G P     H+  PE           S  P  G   DVW  GV+L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>8.87298e-08</Hsp_evalue>
      <Hsp_query-from>766</Hsp_query-from>
      <Hsp_query-to>1173</Hsp_query-to>
      <Hsp_hit-from>184</Hsp_hit-from>
      <Hsp_hit-to>305</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>ETALTVHLLAEHVSGTSLAGHLARTGPLPVETVRQYASQLLHVLDYLHASSVVHRDLRLSSVLLDCATGLLRVADYSLA------RRLADACVASEQPGRPGVPRVHFVEPECGPXXXXXXXRSQPPKTGKKGDVWRLGVLL</Hsp_qseq>
      <Hsp_hseq>ENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTSC------GSP-----HYASPEIVMGR---------PYHGGPSDVWSCGIVL</Hsp_hseq>
      <Hsp_midline>E    ++L+ E+V G  L  +L   G LP      Y  Q++  + Y H+ ++ HRDL+  ++LLD     +++AD+ +A      + L  +C      G P     H+  PE   G          P  G   DVW  G++L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>9.90623e-08</Hsp_evalue>
      <Hsp_query-from>433</Hsp_query-from>
      <Hsp_query-to>1188</Hsp_query-to>
      <Hsp_hit-from>60</Hsp_hit-from>
      <Hsp_hit-to>276</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>114</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>258</Hsp_align-len>
      <Hsp_qseq>KRERLTSMCSSDNCSPGAEVLKFHTQGERSVYRGKCIGESTHLRRQVFNALDNSTGELVVVYEWVLRWPVGHPDLRTSEDKEHMEKCRKQSLLKLR------HEALVPYLGMESQETETALTVHLLAEHVSGTSLAGHLARTGPLPVETVRQYASQLLHVLDYLHASSVVHRDLRLSSVLLDCATGLLRVADYSLARRLADACVASEQPGRPGVPRVHFVEPECGPXXXXXXXRSQPPKTGKKGDVWRLGVLLEQLAV</Hsp_qseq>
      <Hsp_hseq>KREKLSALCKT----PPSLI---KTRG-KDYHRGHFLGEGGFAR--CFQIKDDS-GEIFAAK------TVAKASIKS-------EKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDS----NVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYN-LKIGDFGLAAVLANE--SERKYTICGTP--NYIAPEV--------LMGKHSGHSFEVDIWSLGVMLYALLI</Hsp_hseq>
      <Hsp_midline>KRE+L+++C +    P + +    T+G +  +RG  +GE    R   F   D+S GE+           V    +++       EK RK+ L +++      H  +V ++     ++     V++L E     SL   L R   L    VR + +Q+   + Y+H+  V+HRDL+L ++  D     L++ D+ LA  LA+   +  +    G P  +++ PE            +      + D+W LGV+L  L +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>1.28344e-07</Hsp_evalue>
      <Hsp_query-from>676</Hsp_query-from>
      <Hsp_query-to>1182</Hsp_query-to>
      <Hsp_hit-from>113</Hsp_hit-from>
      <Hsp_hit-to>258</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>170</Hsp_align-len>
      <Hsp_qseq>EHMEKCRKQSLLKL-RHEALVPYLGMESQETETALTVHLLAEHVSGTSLAGHLARTGPLPVETVRQYASQLLHVLDYLHASSVVHRDLRLSSVLLDCATGLLRVADYSLARRLADACVASEQPGRPGVPRVHFVEPECGPXXXXXXXRSQPPKTGKKGDVWRLGVLLEQL</Hsp_qseq>
      <Hsp_hseq>EHTNDERR--MLKLVEHPFLIRMWGT----FQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLD-RNGHIKITDFGFAKEV--QTVTWTLCGTPD-----YIAPEV--------ITTKP--YNKSVDWWSLGVLIYEM</Hsp_hseq>
      <Hsp_midline>EH    R+  +LKL  H  L+   G      + A  + ++ +++ G  L   L ++   P    + YA++++  L+YLHA ++++RDL+  ++LLD   G +++ D+  A+ +    V     G P      ++ PE           ++P    K  D W LGVL+ ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>1.6594e-07</Hsp_evalue>
      <Hsp_query-from>781</Hsp_query-from>
      <Hsp_query-to>1182</Hsp_query-to>
      <Hsp_hit-from>161</Hsp_hit-from>
      <Hsp_hit-to>276</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>134</Hsp_align-len>
      <Hsp_qseq>VHLLAEHVSGTSLAGHLARTGPLPVETVRQYASQLLHVLDYLHASSVVHRDLRLSSVLLDCATGLLRVADYSLARRLADACVASEQPGRPGVPRVHFVEPECGPXXXXXXXRSQPPKTGKKGDVWRLGVLLEQL</Hsp_qseq>
      <Hsp_hseq>VFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLD-KNGHIKITDFGFAKYVPD--VTYTLCGTPD-----YIAPEV--------VSTKP--YNKSVDWWSFGVLIYEM</Hsp_hseq>
      <Hsp_midline>V ++ +++ G  L   L ++   P    + YA+++   L+YLH+  +++RDL+  ++LLD   G +++ D+  A+ + D  V     G P      ++ PE           ++P    K  D W  GVL+ ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>1.78922e-07</Hsp_evalue>
      <Hsp_query-from>766</Hsp_query-from>
      <Hsp_query-to>1182</Hsp_query-to>
      <Hsp_hit-from>155</Hsp_hit-from>
      <Hsp_hit-to>275</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>139</Hsp_align-len>
      <Hsp_qseq>ETALTVHLLAEHVSGTSLAGHLARTGPLPVETVRQYASQLLHVLDYLHASSVVHRDLRLSSVLLDCATGLLRVADYSLARRLADACVASEQPGRPGVPRVHFVEPECGPXXXXXXXRSQPPKTGKKGDVWRLGVLLEQL</Hsp_qseq>
      <Hsp_hseq>QDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLD-KNGHIKITDFGFAKYVPDVTYT-----LCGTP--DYIAPEV--------VSTKP--YNKSIDWWSFGILIYEM</Hsp_hseq>
      <Hsp_midline>+ A  + ++ +++ G  L   L ++   P    + YA+++   L+YLH+  +++RDL+  ++LLD   G +++ D+  A+ + D           G P   ++ PE           ++P    K  D W  G+L+ ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>2.30285e-07</Hsp_evalue>
      <Hsp_query-from>784</Hsp_query-from>
      <Hsp_query-to>1347</Hsp_query-to>
      <Hsp_hit-from>157</Hsp_hit-from>
      <Hsp_hit-to>365</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>222</Hsp_align-len>
      <Hsp_qseq>HLLAEHVSGTSLAGHL-ARTGPLPVETVRQYASQLLHVLDYLHASSVVHRDLRLSSVLLDCATGLLRVADYSLA---RRLADACVASEQPGRPGVPRVHFVEPECGPXXXXXXXRSQPPKTGKKGDVWRLGVLL-------EQLAVKNKLDG--CYYALKR---------------------IAVNPTSRQFRRIKGEVTLLSRLNHENIVRYYNAWIERYE</Hsp_qseq>
      <Hsp_hseq>YIIMEYCSGGDLYEAIKADAVPKKTKSITHIITQIMDAIEYVHNKGIYHRDIKPENILISGIDWTIKLTDWGLATTDKTSMDRNVGSER----------YMSPELFDSNLDIKERKEPYDCAKV-DLWAMGIVFLNIVFHKNPFSIANQSDKSFCYFAANREALFDVFSTMAYDFFQVLRYSLTIDPANRDLKMMRTELQNLSEYTLDD--EYYNNLDEGYE</Hsp_hseq>
      <Hsp_midline>+++ E+ SG  L   + A   P   +++    +Q++  ++Y+H   + HRD++  ++L+      +++ D+ LA   +   D  V SE+          ++ PE          R +P    K  D+W +G++           ++ N+ D   CY+A  R                     + ++P +R  + ++ E+  LS    ++   YYN   E YE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>2.43873e-07</Hsp_evalue>
      <Hsp_query-from>781</Hsp_query-from>
      <Hsp_query-to>1188</Hsp_query-to>
      <Hsp_hit-from>227</Hsp_hit-from>
      <Hsp_hit-to>357</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>138</Hsp_align-len>
      <Hsp_qseq>VHLLAEHVSGTSLAGHLARTGPLPVETVRQYASQLLHVLDYLHASSVVHRDLRLSSVLLDCATGLLRVADYSLARRLA-DACVASEQPGRPGVPRVHFVEPE-CGPXXXXXXXRSQPPKTGKKGDVWRLGVLLEQLAV</Hsp_qseq>
      <Hsp_hseq>LYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLN-QRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQ------NCDWYSLGCLLYDMLV</Hsp_hseq>
      <Hsp_midline>++LL +++ G  L  HL   G L   TV  YA+++   L +LH   VV+RDL+  + LL+   G L + D+ L+++ A D+ V  E P            PE C P      A SQ        D + LG LL  + V</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>2.83206e-07</Hsp_evalue>
      <Hsp_query-from>778</Hsp_query-from>
      <Hsp_query-to>1182</Hsp_query-to>
      <Hsp_hit-from>252</Hsp_hit-from>
      <Hsp_hit-to>382</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>TVHLLAEHVSGTSLAGHLARTGPLPVETVRQYASQLLHVLDYLHASSVVHRDLRLSSVLLDCATGLLRVADYSLARRLADACVASEQP-------GRPGVPRVHFVEPECGPXXXXXXXRSQPPKTGKKGDVWRLGVLLEQL</Hsp_qseq>
      <Hsp_hseq>SLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMK-IKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSF----------TDYRCDIWAFGCILFQM</Hsp_hseq>
      <Hsp_midline>+++ L E+         + + G L     R YA+Q++  +DYLH++ ++HRD++  ++LLD     +++ D+  A+ L     +  +P        +  V    +V PE    +           T  + D+W  G +L Q+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>7.04842e-07</Hsp_evalue>
      <Hsp_query-from>805</Hsp_query-from>
      <Hsp_query-to>1182</Hsp_query-to>
      <Hsp_hit-from>312</Hsp_hit-from>
      <Hsp_hit-to>438</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>141</Hsp_align-len>
      <Hsp_qseq>SGTSLAGHLARTGPLPVETVRQYASQLLHVLDYLHASSVVHRDLRLSSVLLD---------------CATGLLRVADYSLARRLADACVASEQPGRPGVPRVHFVEPECGPXXXXXXXRSQPPKTGKKGDVWRLGVLLEQL</Hsp_qseq>
      <Hsp_hseq>AGDLLAAVMARNGRLEAWLIQRIFTEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLCKKIENNEMCTARCGSED-----YVSPEILMGV---------PYDGHLSDTWALGVILYSL</Hsp_hseq>
      <Hsp_midline>+G  LA  +AR G L    +++  ++++  + YLH +S++HRDL+L ++LL                C    + +AD+ L +++ +  + + + G        +V PE   G          P  G   D W LGV+L  L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>7.91218e-07</Hsp_evalue>
      <Hsp_query-from>736</Hsp_query-from>
      <Hsp_query-to>1182</Hsp_query-to>
      <Hsp_hit-from>885</Hsp_hit-from>
      <Hsp_hit-to>1017</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>149</Hsp_align-len>
      <Hsp_qseq>PYLGMESQETETALTVHLLAEHVSGTSLAGHLARTGPLPVETVRQYASQLLHVLDYLHASSVVHRDLRLSSVLLDCATGLLRVADYSLARRLADACVASEQPGRPGVPRVHFVEPECGPXXXXXXXRSQPPKTGKKGDVWRLGVLLEQL</Hsp_qseq>
      <Hsp_hseq>PFLTNLYCSFQTENRIYFAMEFIGGGDLMWHV-QNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILL-TPEGHIKIADYGLCK--DEMWYGNRTSTFCGTP--EFMAPEI----------LKEQEYTKAVDWWAFGVLLYQM</Hsp_hseq>
      <Hsp_midline>P+L       +T   ++   E + G  L  H+ +   L V   + YA+++L  L Y H + V++RDL+L ++LL    G +++ADY L +   +    +      G P   F+ PE            +  +  K  D W  GVLL Q+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>9.07826e-07</Hsp_evalue>
      <Hsp_query-from>766</Hsp_query-from>
      <Hsp_query-to>1005</Hsp_query-to>
      <Hsp_hit-from>483</Hsp_hit-from>
      <Hsp_hit-to>561</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>80</Hsp_align-len>
      <Hsp_qseq>ETALTVHLLAEHVSGTSLAGHLARTGPLPVETVRQYASQLLHVLDYLHASSVVHRDLRLSSVLLDCATGLLRVADYSLAR</Hsp_qseq>
      <Hsp_hseq>QTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLD-ANGNIALCDFGLSK</Hsp_hseq>
      <Hsp_midline>+T   ++L+ +++SG  L  HL + G    +  + Y ++L+  L++LH + +V+RDL+  ++LLD A G + + D+ L++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>1.62527e-06</Hsp_evalue>
      <Hsp_query-from>571</Hsp_query-from>
      <Hsp_query-to>1194</Hsp_query-to>
      <Hsp_hit-from>39</Hsp_hit-from>
      <Hsp_hit-to>215</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>215</Hsp_align-len>
      <Hsp_qseq>VFNALDNSTGELVVVYEWVLRWPVGHPDLRTSEDKEHMEKCRKQSLLK-LRHEALVPYLGMESQETETALTVHLLAEHVSGTSLAGHLARTGP-LPVETVRQYASQLLHVLDYLHASSVVHRDLRLSSVLLDCATGLLRVADYSLARRLADACVASEQPGRPGVPRVHFVEPECGPXXXXXXXRSQPPKTGKKG-----DVWRLGVLLEQLAVKN</Hsp_qseq>
      <Hsp_hseq>VYKAINKHTDQVVAIKEVVYE-----------NDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYE----LYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILL-SADNTVKLADFGVS-----TIVNSSALTLAGT--LNWMAPEI---------------LGNRGASTLSDIWSLGATVVEMLTKN</Hsp_hseq>
      <Hsp_midline>V+ A++  T ++V + E V              D+E  +   + SLLK L H  +V Y G   +  E    +++L E+ +  SL   ++R+   L     + Y +Q L  L YLH   V+HRD++ +++LL  A   +++AD+ ++       V S      G   ++++ PE                 G +G     D+W LG  + ++  KN</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>1.7561e-06</Hsp_evalue>
      <Hsp_query-from>847</Hsp_query-from>
      <Hsp_query-to>1011</Hsp_query-to>
      <Hsp_hit-from>136</Hsp_hit-from>
      <Hsp_hit-to>190</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>37</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>55</Hsp_align-len>
      <Hsp_qseq>LPVETVRQYASQLLHVLDYLHASSVVHRDLRLSSVLLDCATGLLRVADYSLARRL</Hsp_qseq>
      <Hsp_hseq>MPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKL</Hsp_hseq>
      <Hsp_midline>+P++ +R Y  Q+   + YLH   V HRD++ S+VL+D  TG+L++ D+  A++L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>2.01019e-06</Hsp_evalue>
      <Hsp_query-from>571</Hsp_query-from>
      <Hsp_query-to>1005</Hsp_query-to>
      <Hsp_hit-from>212</Hsp_hit-from>
      <Hsp_hit-to>344</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>146</Hsp_align-len>
      <Hsp_qseq>VFNALDNSTGELVVVYEWVLRWPVGHPDLRTSEDKEHMEKCRKQSLLKLRHEALVPYLGMESQETETALTVHLLAEHVSGTSLAGHLARTGPLPVETVRQYASQLLHVLDYLHASSVVHRDLRLSSVLLDCAT-GLLRVADYSLAR</Hsp_qseq>
      <Hsp_hseq>VKKAIERTTGKTFAVKIISKRKVIGNMDGVTRE---------LEVLQKLNHPRIVRLKGF-YEDTES---YYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAK</Hsp_hseq>
      <Hsp_midline>V  A++ +TG+   V     R  +G+ D  T E          + L KL H  +V   G   ++TE+    +++ E VSG  L   +A  G +  +  R+ + Q+L  + Y+H+  + HRDL+  ++L++     L+++ D+ LA+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>3.1873e-06</Hsp_evalue>
      <Hsp_query-from>694</Hsp_query-from>
      <Hsp_query-to>1173</Hsp_query-to>
      <Hsp_hit-from>102</Hsp_hit-from>
      <Hsp_hit-to>242</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>162</Hsp_align-len>
      <Hsp_qseq>RKQSLLKL-RHEALVPYLGMESQETETALTVHLLAEHVSGTSLAGHLARTGPLPVETVRQYASQLLHVLDYLHASSVVHRDLRLSSVLLDCATGLLRVADYSLARRLADACVASEQPGRPGVPRVHFVEPECG-PXXXXXXXRSQPPKTGKKGDVWRLGVLL</Hsp_qseq>
      <Hsp_hseq>REISYLRLLRHPHIIKLYDVIKSKDEIIMVIEY-----AGNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLN-VKIADFGLSNIMTDG---------------NFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVIL</Hsp_hseq>
      <Hsp_midline>R+ S L+L RH  ++    +   + E  + +       +G  L  ++ +   +  +  R++  Q++  ++Y H   +VHRDL+  ++LLD     +++AD+ L+  + D                +F++  CG P   A    S     G + DVW  GV+L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>6.31929e-06</Hsp_evalue>
      <Hsp_query-from>694</Hsp_query-from>
      <Hsp_query-to>1005</Hsp_query-to>
      <Hsp_hit-from>69</Hsp_hit-from>
      <Hsp_hit-to>167</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>107</Hsp_align-len>
      <Hsp_qseq>RKQSLLK-LRHEALVPYLGMESQETETALTVHLLAEHVSGTSLAGHLARTGPLPVETVRQYASQLLHVLDYLHASSVVHRDLRLSSVLL--DCATGLLRVADYSLAR</Hsp_qseq>
      <Hsp_hseq>RELKLLKHLRHENLICLQDIFLSPLED---IYFVTE-LQGTDLH-RLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCD---LKICDFGLAR</Hsp_hseq>
      <Hsp_midline>R+  LLK LRHE L+    +     E    ++ + E + GT L   L +T PL  + V+ +  Q+L  L Y+H++ V+HRDL+ S++L+  +C    L++ D+ LAR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>105</Statistics_hsp-len>
      <Statistics_eff-space>4464344670</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054884-RA transcript Note:&quot;Similar to SUPT5H Transcription elongation factor SPT5 (Gallus gallus)&quot; offset:262 AED:0.12 eAED:0.12 QI:262|0.88|0.92|1|0.37|0.46|28|1738|1034</Iteration_query-def>
  <Iteration_query-len>5105</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YML010W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:247677:250868:1 gene:YML010W transcript:YML010W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPT5 description:Spt4p/5p (DSIF) transcription elongation factor complex subunit; the Spt4/5 complex binds to ssRNA in a sequence-specific manner, and in concert with RNAP I and II has multiple roles regulating transcriptional elongation, RNA processing, quality control, and transcription-coupled repair; interacts with DNA upstream of RNAPII and the non-template strand of the transcription bubble; Spt5p is the only transcription elongation factor conserved in all domains of life [Source:SGD;Acc:S000004470]</Hit_def>
  <Hit_accession>YML010W</Hit_accession>
  <Hit_len>1063</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>214.542</Hsp_bit-score>
      <Hsp_score>545</Hsp_score>
      <Hsp_evalue>5.98279e-57</Hsp_evalue>
      <Hsp_query-from>728</Hsp_query-from>
      <Hsp_query-to>2389</Hsp_query-to>
      <Hsp_hit-from>287</Hsp_hit-from>
      <Hsp_hit-to>845</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>166</Hsp_identity>
      <Hsp_positive>288</Hsp_positive>
      <Hsp_gaps>55</Hsp_gaps>
      <Hsp_align-len>584</Hsp_align-len>
      <Hsp_qseq>LWTVKCKLGEERATAIGLMRKFIAYQFS------DTPMQIKSVIAPEHLKGYIYIEAYKQTHVKQAIEGVGNLRMGFWNQQMVPIKEMTDVMK-VVNEVTNLKPKSWVRLRRGIFKDDIAQVDYVEPSQNTIGLKLIPRIDYERI-------KSRMSMKDWFAKRKRYKRPPQRLFDVDKIRSLGGEV-TSDGDFLQFEGNKYTRKGFLIKGFAMSAVIIEGVKPTLSELEKFEDQPEGVDLELVSEA-------------KDNVEVCEGELINLQGTVLSVDGNKITIMPKHEDLKDPLEFPAHELRKYFKIGDHVKVIAGRYEGDTGLIVRAEENFVILFSDLTMHELKVLPRDLQLCSETASGVDSGGQHEWGELVLLDPQTVGVIVRLERETFQVLNMYGKVVTLKHQAVTKKRDNRHA--VALDSEQNNIQVKDIVKVIDGPHSGREGEVRHLYRSFAFLHSKRLVENGGMFVCKTRHVVLAGGAKPRDVTNFSVGTFAPKSPRLASPMHPSXXXXXXXXXXXXXXXXXXDTELIGQTVRITHGPYKGYIGVVKDATESTARVELHSTCQTISVDRTRL</Hsp_qseq>
      <Hsp_hseq>IWGVRCRPGKEKE----LIRKLLKKKFNLDRAMGKKKLKILSIFQRDNYTGRIYIEAPKQSVIEKFCNGVPDIYIS--QKLLIPVQELPLLLKPNKSDDVALEEGSYVRIKRGIYKGDLAMVDQISENNLEVMLKIVPRLDYGKFDEIDPTTQQRKSRRPTFAHRA----PPQLFNPTMALRLDQANLYKRDDRHFTYKNEDYI-DGYLYKSFRIQHVETKNIQPTVEELARFGSKEGAVDLTSVSQSIKKAQAAKVTFQPGDRIEVLNGEQRGSKGIVTRTTKDIATI--KLNGFTTPLEFPISTLRKIFEPGDHVTVINGEHQGDAGLVLMVEQGQVTFMSTQTSREVTITANNLSKSIDTTA---TSSEYALHDIVELSAKNVACIIQAGHDIFKVIDETGKVSTITKGSILSKINTARARVSSVDANGNEIKIGDT--IVEKVGSRREGQVLYIQTQQIFVVSKKIVENAGVFVVNPSNVE-AVASKDNMLSNKM--DLSKMNPEIISKMGPPSSKTFQQPIQSRGGREVA----LGKTVRIRSAGYKGQLGIVKDVNGDKATVELHSKNKHITIDKHKL</Hsp_hseq>
      <Hsp_midline>+W V+C+ G+E+     L+RK +  +F+         ++I S+   ++  G IYIEA KQ+ +++   GV ++ +    + ++P++E+  ++K   ++   L+  S+VR++RGI+K D+A VD +  +   + LK++PR+DY +        + R S +  FA R     PPQ       +R     +   D     ++   Y   G+L K F +  V  + ++PT+ EL +F  +   VDL  VS++              D +EV  GE    +G V     +  TI  K      PLEFP   LRK F+ GDHV VI G ++GD GL++  E+  V   S  T  E+ +   +L    +T +   +  ++   ++V L  + V  I++   + F+V++  GKV T+   ++  K +   A   ++D+  N I++ D   +++   S REG+V ++     F+ SK++VEN G+FV    +V  A  +K   ++N      +  +P + S M P      +       GR       +G+TVRI    YKG +G+VKD     A VELHS  + I++D+ +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3570358666</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0043074-RA transcript Note:&quot;Similar to CDC42EP2 Cdc42 effector protein 2 (Homo sapiens)&quot; offset:0 AED:0.28 eAED:0.36 QI:0|0.5|0|1|0|0|3|1282|317</Iteration_query-def>
  <Iteration_query-len>2236</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1473465816</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054919-RA transcript Note:&quot;Similar to acp7 Acid phosphatase type 7 (Danio rerio)&quot; offset:886 AED:0.19 eAED:0.19 QI:886|0.92|1|1|0|0|14|309|379</Iteration_query-def>
  <Iteration_query-len>2335</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1548503427</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0000460-RA transcript Note:&quot;Similar to Gpr176 G-protein coupled receptor 176 (Mus musculus)&quot; offset:0 AED:0.01 eAED:0.01 QI:0|0|0|1|1|1|2|0|470</Iteration_query-def>
  <Iteration_query-len>1413</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>93</Statistics_hsp-len>
      <Statistics_eff-space>869500926</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0000461-RB transcript Note:&quot;Similar to fsip1 Fibrous sheath-interacting protein 1 (Xenopus laevis)&quot; offset:70 AED:0.70 eAED:0.70 QI:70|0.9|0.72|0.90|0|0|11|1837|567</Iteration_query-def>
  <Iteration_query-len>3611</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2476708634</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0000463-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.38 eAED:0.40 QI:0|0.4|0.66|0.83|0|0|6|0|224</Iteration_query-def>
  <Iteration_query-len>675</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>86</Statistics_hsp-len>
      <Statistics_eff-space>326158913</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054921-RA transcript Note:&quot;Similar to Srsf5 Serine/arginine-rich splicing factor 5 (Rattus norvegicus)&quot; offset:985 AED:0.26 eAED:0.26 QI:985|0.6|1|1|0|0|6|650|310</Iteration_query-def>
  <Iteration_query-len>2568</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDR432W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1328783:1330027:1 gene:YDR432W transcript:YDR432W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NPL3 description:RNA-binding protein; promotes elongation, regulates termination, and carries poly(A) mRNA from nucleus to cytoplasm; represses translation initiation by binding eIF4G; required for pre-mRNA splicing; interacts with E3 ubiquitin ligase Bre1p, linking histone ubiquitination to mRNA processing; may have role in telomere maintenance; dissociation from mRNAs promoted by Mtr10p; phosphorylated by Sky1p in cytoplasm; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002840]</Hit_def>
  <Hit_accession>YDR432W</Hit_accession>
  <Hit_len>414</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>6.67384e-11</Hsp_evalue>
      <Hsp_query-from>1181</Hsp_query-from>
      <Hsp_query-to>1618</Hsp_query-to>
      <Hsp_hit-from>123</Hsp_hit-from>
      <Hsp_hit-to>270</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>148</Hsp_align-len>
      <Hsp_qseq>SSSRVFIARLGPHVRTKDVEKFFKGYGKIRDIDIKAGFGFVEFXXXXXXXXXXXXLNGRELNNESSGGRYGPPSRTDHRLVVENLSSTVSWQDLKDYMRQAG-EVTFADAH-RIHQNVGVVEFATRNDMKNAIDKLNGKEINGRKIKL</Hsp_qseq>
      <Hsp_hseq>SNTRLFVRPFPLDVQESELNEIFGPFGPMKEVKILNGFAFVEFEEAESAAKAIEEVHGKSFANQPLEVVYSKLPAKRYRITMKNLPEGCSWQDLKDLARENSLETTFSSVNTRDFDGTGALEFPSEEILVEALERLNNIEFRGSVITV</Hsp_hseq>
      <Hsp_midline>S++R+F+      V+  ++ + F  +G ++++ I  GF FVEF++   A  A+ +++G+   N+     Y       +R+ ++NL    SWQDLKD  R+   E TF+  + R     G +EF +   +  A+++LN  E  G  I +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YNL004W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:622915:624621:1 gene:YNL004W transcript:YNL004W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRB1 description:Poly(A+) RNA-binding protein; key surveillance factor for the selective export of spliced mRNAs from the nucleus to the cytoplasm; preference for intron-containing genes; similar to Npl3p; HRB1 has a paralog, GBP2, that arose from the whole genome duplication [Source:SGD;Acc:S000004949]</Hit_def>
  <Hit_accession>YNL004W</Hit_accession>
  <Hit_len>454</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>8.08888e-07</Hsp_evalue>
      <Hsp_query-from>1094</Hsp_query-from>
      <Hsp_query-to>1603</Hsp_query-to>
      <Hsp_hit-from>139</Hsp_hit-from>
      <Hsp_hit-to>328</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>199</Hsp_align-len>
      <Hsp_qseq>YGLWLAHLLVCFVSRIFHRLVFCQVSNMSSSSRVFIARLGPHVRTKDVEKFFKGYGKIRDIDI------KAGFGFVEFXXXXXXXXXXXXLNGRELNNESSGGRYG--PPS-----------------RTDHRLVVENLSSTVSWQDLKDYMRQAGEVTFA----DAHRIHQNVGVVEFATRNDMKNAIDKLNGKEING</Hsp_qseq>
      <Hsp_hseq>YGPLLARELDS---------TYEEKVNRNYSNSIFVGNLTYDSTPEDLTEFFSQIGKVVRADIITSRGHHRGMGTVEFTNSDDVDRAIRQYDGAFFMDRKIFVRQDNPPPSNNIKERKALDRGELRHNRKTHEVIVKNLPASVNWQALKDIFKECGNVAHADVELDGDGVSTGSGTVSFYDIKDLHRAIEKYNGYSIEG</Hsp_hseq>
      <Hsp_midline>YG  LA  L            + +  N + S+ +F+  L      +D+ +FF   GK+   DI        G G VEF +  D D A+   +G    +     R    PPS                 R  H ++V+NL ++V+WQ LKD  ++ G V  A    D   +    G V F    D+  AI+K NG  I G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1718588386</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0028647-RA transcript Note:&quot;Similar to PRKD1 Serine/threonine-protein kinase D1 (Homo sapiens)&quot; offset:0 AED:0.29 eAED:0.29 QI:0|-1|0|1|-1|1|1|0|103</Iteration_query-def>
  <Iteration_query-len>312</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>74</Statistics_hsp-len>
      <Statistics_eff-space>72770010</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0043057-RA transcript Note:&quot;Similar to PRKD3 Serine/threonine-protein kinase D3 (Homo sapiens)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.5|0.66|3|0|123</Iteration_query-def>
  <Iteration_query-len>372</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>78</Statistics_hsp-len>
      <Statistics_eff-space>110366282</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0026034-RA transcript Note:&quot;Similar to Prkd3 Serine/threonine-protein kinase D3 (Mus musculus)&quot; offset:0 AED:0.32 eAED:0.35 QI:0|0.25|0.23|0.92|0.33|0.38|13|0|597</Iteration_query-def>
  <Iteration_query-len>1794</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>108.612</Hsp_bit-score>
      <Hsp_score>270</Hsp_score>
      <Hsp_evalue>4.26619e-25</Hsp_evalue>
      <Hsp_query-from>844</Hsp_query-from>
      <Hsp_query-to>1509</Hsp_query-to>
      <Hsp_hit-from>201</Hsp_hit-from>
      <Hsp_hit-to>457</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>126</Hsp_positive>
      <Hsp_gaps>57</Hsp_gaps>
      <Hsp_align-len>268</Hsp_align-len>
      <Hsp_qseq>DEVLGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQESQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHG-DMLEMILSSEKGRLPERNTKFLVTQASRR-GRRILVALRHLHFKNIVHCDLKPENVLLASADPF------------------------------PQVIRSKQG------------YNRSLDMWSVGVIVYVSLSGTFPF--NEDEDINEQIQNAAFMYPPNPWKEITQDAIDLINNLLQVKMRKRYTS</Hsp_qseq>
      <Hsp_hseq>DEVVGQGAFATVKKAIERTTGKTFAVKIISKRKVIGNMDGVTR-ELEVLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFV--AAHGAVGE--------DAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGPLKDFRISEEARDFIDSLLQVDPNNRSTA</Hsp_hseq>
      <Hsp_midline>DEV+G G F  V     R TG   A+K+I K +     +   R E+ +LQ L+HP +V L+  +E  E  ++VME + G D+++ +  +  G + E         A R   R+IL A++++H   I H DLKP+N+L+   DP                               P+VIR K              Y+  +DMWS+G +VYV L+G  PF  +  + + +QI   ++   P     I+++A D I++LLQV    R T+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>100.138</Hsp_bit-score>
      <Hsp_score>248</Hsp_score>
      <Hsp_evalue>5.19373e-23</Hsp_evalue>
      <Hsp_query-from>847</Hsp_query-from>
      <Hsp_query-to>1368</Hsp_query-to>
      <Hsp_hit-from>41</Hsp_hit-from>
      <Hsp_hit-to>239</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>43</Hsp_gaps>
      <Hsp_align-len>208</Hsp_align-len>
      <Hsp_qseq>EVLGSGQFGIVYGGKHRKTGSDVAIKVIDK--LRFPTKQESQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHG-DMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVL-LASADPFPQVIR------------------------------SKQGYNRSLDMWSVGVIVYVSLSGTFPF</Hsp_qseq>
      <Hsp_hseq>KTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRIL--KKGKFTEEDAVRILVE-------ILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAF</Hsp_hseq>
      <Hsp_midline>+ LG+G FG+V   K+ +TG DVA+K++ K  L+    Q   L +E+ ILQ LHHP +V  +  FE+ ++ +++ +   G ++ + IL  +KG+  E +   ++ +       IL A++++H +NIVH DLKPEN+L +  +D  P V+                               ++ G+ +  D+WS+GVI Y  L G   F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>98.9821</Hsp_bit-score>
      <Hsp_score>245</Hsp_score>
      <Hsp_evalue>1.96831e-22</Hsp_evalue>
      <Hsp_query-from>853</Hsp_query-from>
      <Hsp_query-to>1515</Hsp_query-to>
      <Hsp_hit-from>206</Hsp_hit-from>
      <Hsp_hit-to>473</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>125</Hsp_positive>
      <Hsp_gaps>67</Hsp_gaps>
      <Hsp_align-len>278</Hsp_align-len>
      <Hsp_qseq>LGSGQFGIVYGGKHRKTGSDVAIKVID-KLRFPTKQESQLRNEVAILQSLHHPGVVNLQSMFETPE-----RVFVVMEKLH-GDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPEN-------------------------VLLASAD----------------------PFPQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNED---EDINEQIQNAAFMYPPNPWKEITQDAIDLINNLLQVKMRKRYTSEQ</Hsp_qseq>
      <Hsp_hseq>LGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALF---------KQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVL-TKKGYTSKVDLWSAGVILYVCLCGFPPFSDQLGPPSLKEQILQAKYAFYSPYWDKIDDSVLHLISNLLVLNPDERYNIDE</Hsp_hseq>
      <Hsp_midline>LG+G + +V   K++KTG  VA+K+   +     K+  Q R E  IL  + HP +VNL   F  P      + ++V+EK+  G++ E I+     R  E    F         +++L  L++LH +NI+H D+KPEN                         + +  AD                        P+V+ +K+GY   +D+WS GVI+YV L G  PF++      + EQI  A + +    W +I    + LI+NLL +   +RY  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>96.6709</Hsp_bit-score>
      <Hsp_score>239</Hsp_score>
      <Hsp_evalue>5.5941e-22</Hsp_evalue>
      <Hsp_query-from>823</Hsp_query-from>
      <Hsp_query-to>1518</Hsp_query-to>
      <Hsp_hit-from>85</Hsp_hit-from>
      <Hsp_hit-to>330</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>260</Hsp_align-len>
      <Hsp_qseq>QVYQIFPDEVLGSGQFGIVYGGKHRKTGSDVAIKVIDK-LRFPTKQESQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLL-------------------------ASADPFPQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNEDEDIN--EQIQNAAFMYPPNPWKEITQDAIDLINNLLQVKMRKRYTSEQD</Hsp_qseq>
      <Hsp_hseq>QDFQIL--RTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQ-RFPNPVAKFYAAE-------VCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPF----FNEDVKDLLSRLITRDLSQRLGNLQN</Hsp_hseq>
      <Hsp_midline>Q +QI     LG+G FG V+  + R  G   A+KV+ K +    KQ     +E  +L  + HP ++ +   F+  +++F++M+ + G  L  +L   + R P    KF   +       + +AL +LH K+I++ DLKPEN+LL                          + D     + S + YN+S+D WS G+++Y  L+G  PF +   +   E+I NA   +PP       +D  DL++ L+   + +R  + Q+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>96.2857</Hsp_bit-score>
      <Hsp_score>238</Hsp_score>
      <Hsp_evalue>1.03457e-21</Hsp_evalue>
      <Hsp_query-from>853</Hsp_query-from>
      <Hsp_query-to>1368</Hsp_query-to>
      <Hsp_hit-from>53</Hsp_hit-from>
      <Hsp_hit-to>249</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>207</Hsp_align-len>
      <Hsp_qseq>LGSGQFGIVYGGKHRKTGSDVAIKVIDK--LRFPTKQESQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVME-KLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVL---------LASAD-----------------------PFPQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPF</Hsp_qseq>
      <Hsp_hseq>LGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILS--RGKFTEVDAVEIIVQ-------ILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVL-TQDGHGKPCDIWSIGVITYTLLCGYSPF</Hsp_hseq>
      <Hsp_midline>LG+G FG+V   +   T  DVAIK++ K  L+    Q   L  E++ILQ L HP +V+ +  FE+ ++ ++V +    G++ + ILS  +G+  E +   ++ Q       IL A+ ++H KN+VH DLKPENVL         L  AD                         P+V+ ++ G+ +  D+WS+GVI Y  L G  PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.1301</Hsp_bit-score>
      <Hsp_score>235</Hsp_score>
      <Hsp_evalue>1.29333e-21</Hsp_evalue>
      <Hsp_query-from>853</Hsp_query-from>
      <Hsp_query-to>1500</Hsp_query-to>
      <Hsp_hit-from>76</Hsp_hit-from>
      <Hsp_hit-to>307</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>245</Hsp_align-len>
      <Hsp_qseq>LGSGQFGIVYGGKHRKTGSDVAIKVIDKLRF-PTKQESQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLL-------------------------ASADPF-PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNEDEDIN--EQIQNAAFMYPPNPWKEITQDAIDLINNLLQVKMRKR</Hsp_qseq>
      <Hsp_hseq>LGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQ-RFPNPVAKFYAAE-------VILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTPDYIAPEVITTKP-YNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPY----FHPDVVDLLSKLITADLTRR</Hsp_hseq>
      <Hsp_midline>LG+G FG V+  +    G   AIKV+ K +    KQ     +E  +L+ + HP ++ +   F+    +F+VM+ + G  L  +L   + R P    KF   +       +++AL +LH  NI++ DLKPEN+LL                          + D   P+VI +K  YN+S+D WS+GV++Y  L+G  PF +   +   E+I     +YPP        D +DL++ L+   + +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>96.6709</Hsp_bit-score>
      <Hsp_score>239</Hsp_score>
      <Hsp_evalue>3.02491e-21</Hsp_evalue>
      <Hsp_query-from>847</Hsp_query-from>
      <Hsp_query-to>1500</Hsp_query-to>
      <Hsp_hit-from>25</Hsp_hit-from>
      <Hsp_hit-to>273</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>53</Hsp_gaps>
      <Hsp_align-len>260</Hsp_align-len>
      <Hsp_qseq>EVLGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQES---------QLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLH-GDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLAS-----------------ADPF-----------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNEDE----DINEQIQNAAFMYPPNPWKEITQDAIDLINNLLQVKMRKR</Hsp_qseq>
      <Hsp_hseq>ETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLV--DHGPLPER-------EAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPND--TEISRDAQDLIGKILVVDPRQR</Hsp_hseq>
      <Hsp_midline>E LG G  G V   +H +TG   A+KVI K  F                +  E+ I++ L HP V++L  ++ET   +++++E    G++  +++  + G LPER       +A    R+I++ + + H   IVH DLKPEN+LL S                 AD             P+++        + D+WS GVI++  L+G  PF+E+     D+  ++Q   F  P +   EI++DA DLI  +L V  R+R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>92.0485</Hsp_bit-score>
      <Hsp_score>227</Hsp_score>
      <Hsp_evalue>1.75759e-20</Hsp_evalue>
      <Hsp_query-from>850</Hsp_query-from>
      <Hsp_query-to>1518</Hsp_query-to>
      <Hsp_hit-from>93</Hsp_hit-from>
      <Hsp_hit-to>331</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>251</Hsp_align-len>
      <Hsp_qseq>VLGSGQFGIVYGGKHRKTGSDVAIKVIDKLRF-PTKQESQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLL-------------------------ASADPFPQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNEDEDIN--EQIQNAAFMYPPNPWKEITQDAIDLINNLLQVKMRKRYTSEQD</Hsp_qseq>
      <Hsp_hseq>TLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQ-RFPNPVAKFYAAE-------VCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPF----FHPDAQDLLKKLITRDLSERLGNLQN</Hsp_hseq>
      <Hsp_midline> LG+G FG V+  +    G   A+K + K      KQ     +E  +L  + HP ++ +   F+  ++VF+VM+ + G  L  +L   + R P    KF   +       + +AL +LH K+I++ DLKPEN+LL                          + D     + S + YN+S+D WS GV++Y  L+G  PF     +   E I NA   +PP        DA DL+  L+   + +R  + Q+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.1225</Hsp_bit-score>
      <Hsp_score>222</Hsp_score>
      <Hsp_evalue>3.4046e-19</Hsp_evalue>
      <Hsp_query-from>847</Hsp_query-from>
      <Hsp_query-to>1500</Hsp_query-to>
      <Hsp_hit-from>23</Hsp_hit-from>
      <Hsp_hit-to>277</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>127</Hsp_positive>
      <Hsp_gaps>65</Hsp_gaps>
      <Hsp_align-len>269</Hsp_align-len>
      <Hsp_qseq>EVLGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQESQ---------------LRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLH-GDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLAS------AD----------------------PFPQVIRS--KQGYNRSLDMWSVGVIVYVSLSGTFPFNEDEDIN-----EQIQNAAFMYPPNPWKEITQDAIDLINNLLQVKMRKR</Hsp_qseq>
      <Hsp_hseq>ETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLV--ERGPLPEH-------EAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQGF--ASDVWSCGVILFALLTGRLPFDE-EDGNIRTLLLKVQKGEFEMPSDD--EISREAQDLIRKILTVDPERR</Hsp_hseq>
      <Hsp_midline>E LG G  G V   ++  TG + A+KVI K  F T   S                +  E+ I++ L+HP V+ L  ++ET   +++V+E    G++  +++  E+G LPE        +A R  R+I++ + + H   IVH DLKPEN+LL        AD                        P+++     QG+  + D+WS GVI++  L+G  PF+E ED N      ++Q   F  P +   EI+++A DLI  +L V   +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.8853</Hsp_bit-score>
      <Hsp_score>211</Hsp_score>
      <Hsp_evalue>1.34408e-18</Hsp_evalue>
      <Hsp_query-from>877</Hsp_query-from>
      <Hsp_query-to>1500</Hsp_query-to>
      <Hsp_hit-from>118</Hsp_hit-from>
      <Hsp_hit-to>343</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>240</Hsp_align-len>
      <Hsp_qseq>VYGGKHRKTGSDVAIKVIDKLRF-PTKQESQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKL-HGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLASADPF----------------------------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNED--EDINEQIQNAAFMYPPNPWKEITQDAIDLINNLLQVKMRKR</Hsp_qseq>
      <Hsp_hseq>VYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLL------RL---HGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESRE-YDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMPSN----ISQDAQDLILKLLKYDPKDR</Hsp_hseq>
      <Hsp_midline>VY  +HR TG   A+KV++K        + Q R EV I  SL+HP +      F   +RV+++ME L +G+M +++      RL   +  F    AS    +I  AL ++H KNI+H D+KPEN+L+   +                              P+++ S++ Y+ ++D W++GV+ +  L+G  PF E+  +   ++I       P N    I+QDA DLI  LL+   + R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.6557</Hsp_bit-score>
      <Hsp_score>213</Hsp_score>
      <Hsp_evalue>3.40212e-18</Hsp_evalue>
      <Hsp_query-from>850</Hsp_query-from>
      <Hsp_query-to>1518</Hsp_query-to>
      <Hsp_hit-from>417</Hsp_hit-from>
      <Hsp_hit-to>661</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>254</Hsp_align-len>
      <Hsp_qseq>VLGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQESQL----RNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLAS-------------------ADPF--------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNEDEDINEQIQNAAFMYPPNPWKEITQDAIDLINNLLQVKMRKRYTSEQD</Hsp_qseq>
      <Hsp_hseq>LLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKE-GRFSEDRAKFYIAE-------LVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFA-ENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNRNPKHRLGAIDD</Hsp_hseq>
      <Hsp_midline>+LG G FG VY  K + T    A+KV+ K     K E       RN +    S   P +V L+  F+TP  +++V + + G  L   L  E GR  E   KF + +       +++AL HLH  +IV+ DLKPEN+LL +                    + F        P+++  + GY + +D WS+GV+++    G  PF   E+  +  Q  AF     P   ++Q+    +  LL    + R  +  D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.5001</Hsp_bit-score>
      <Hsp_score>210</Hsp_score>
      <Hsp_evalue>6.77893e-18</Hsp_evalue>
      <Hsp_query-from>829</Hsp_query-from>
      <Hsp_query-to>1485</Hsp_query-to>
      <Hsp_hit-from>55</Hsp_hit-from>
      <Hsp_hit-to>289</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>119</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>251</Hsp_align-len>
      <Hsp_qseq>YQIFPDEVLGSGQFGIVYGGKHRKTGSDVAIKVIDK-LRFPTKQESQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLAS------AD----------------------PFPQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNEDEDI---NEQIQNAAFMYPPNPWKEITQDAIDLINNLLQV</Hsp_qseq>
      <Hsp_hseq>YQIV--KTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGNELFDYIV--QRDKMSEQ-------EARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPF-DDESIPVLFKNISNGVYTLP----KFLSPGAAGLIKRMLIV</Hsp_hseq>
      <Hsp_midline>YQI   + LG G FG V    H  TG  VA+K+I+K +   +  + ++  E++ L+ L HP ++ L  + ++ + + +V+E    ++ + I+  ++ ++ E+       +A R  ++I+ A+ + H   IVH DLKPEN+LL        AD                        P+VI  K      +D+WS GVI+YV L    PF +DE I    + I N  +  P    K ++  A  LI  +L V</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.9593</Hsp_bit-score>
      <Hsp_score>206</Hsp_score>
      <Hsp_evalue>1.95798e-17</Hsp_evalue>
      <Hsp_query-from>781</Hsp_query-from>
      <Hsp_query-to>1512</Hsp_query-to>
      <Hsp_hit-from>304</Hsp_hit-from>
      <Hsp_hit-to>590</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>79</Hsp_identity>
      <Hsp_positive>128</Hsp_positive>
      <Hsp_gaps>65</Hsp_gaps>
      <Hsp_align-len>298</Hsp_align-len>
      <Hsp_qseq>RCRTVKFKRTW-DISQVYQIFPD-EVLGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQE-SQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGR-LPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLAS----------------------------------ADPF-------------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNEDEDINEQIQN---AAFMYPPNPWKEITQDAIDLINNLLQVKMRKRYTSE</Hsp_qseq>
      <Hsp_hseq>RLRTKSFGNKFQDITVEPQSFEKIRLLGQGDVGKVYLVRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASE-------VVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRG-NGHTAAVDWWTLGILIYEMLFGCTPFKGD-NSNETFSNILTKDVKFPHD--KEVSKNCKDLIKKLLNKNEAKRLGSK</Hsp_hseq>
      <Hsp_midline>R RT  F   + DI+   Q F    +LG G  G VY  + R T    A+KV++K     +++  ++  E  IL +  HP +V L   F+T + +++ ME   G      L + K + + E + KF  ++       ++ AL +LH    ++ DLKPEN+LL                                    +D F             P+VIR   G+  ++D W++G+++Y  L G  PF  D + NE   N       +P +  KE++++  DLI  LL     KR  S+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.8702</Hsp_bit-score>
      <Hsp_score>185</Hsp_score>
      <Hsp_evalue>8.45145e-15</Hsp_evalue>
      <Hsp_query-from>850</Hsp_query-from>
      <Hsp_query-to>1383</Hsp_query-to>
      <Hsp_hit-from>51</Hsp_hit-from>
      <Hsp_hit-to>257</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>215</Hsp_align-len>
      <Hsp_qseq>VLGSGQFGIVYGGKHRKTGSD-----VAIKVI--DKLRFPTKQESQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLASADPF-----------------------------PQVIRSKQGYN-RSLDMWSVGVIVYVSLSGTFPFNEDED</Hsp_qseq>
      <Hsp_hseq>TLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQ-RKRRLKESSACRLFAQ-------LISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLPWDDDHE</Hsp_hseq>
      <Hsp_midline> LG G+FG V  G  + + S+     VAIK+I  D ++    +E ++  E+  L+ L HP ++ L+ + +  + + +V+E + G      +   K RL E +   L  Q       ++  + ++H+K +VH DLK EN+LL   +                               P+++ S + Y  R  D+WS GVI+Y  L+G  P+++D +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.0998</Hsp_bit-score>
      <Hsp_score>183</Hsp_score>
      <Hsp_evalue>1.54252e-14</Hsp_evalue>
      <Hsp_query-from>847</Hsp_query-from>
      <Hsp_query-to>1620</Hsp_query-to>
      <Hsp_hit-from>29</Hsp_hit-from>
      <Hsp_hit-to>303</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>290</Hsp_align-len>
      <Hsp_qseq>EVLGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQE-SQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLASADPF--------------------------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNE--DEDINEQIQNAAFMYPPNPWKEITQDAIDLINNLLQVKMRKRYTSEQDYQ-TWLDLRE-LEVRRSERYVTHESD-DARWERHAAE</Hsp_qseq>
      <Hsp_hseq>QVIGRGSYGVVYKAINKHTDQVVAIK---EVVYENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQT-------LLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSALTLAGTLNWMAPEILGNRGASTLS-DIWSLGATVVEMLTKNPPYHNLTDANIYYAVENDTY-YPPSSFSEPLK---DFLSKCFVKNMYKRPTADQLLKHVWINSTENVKVDKLNKFKEDFTDADYHWDADFQE</Hsp_hseq>
      <Hsp_midline>+V+G G +G+VY   ++ T   VAIK   ++ +   +E + +  E+++L++L+H  +V           +++++E      L  ++S     L E  +K  VTQ        L+ L++LH + ++H D+K  N+LL++ +                            P+++ ++     S D+WS+G  V   L+   P++   D +I   ++N  + YPP+ + E  +   D ++      M KR T++Q  +  W++  E ++V +  ++    +D D  W+    E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.559</Hsp_bit-score>
      <Hsp_score>179</Hsp_score>
      <Hsp_evalue>3.33945e-14</Hsp_evalue>
      <Hsp_query-from>847</Hsp_query-from>
      <Hsp_query-to>1479</Hsp_query-to>
      <Hsp_hit-from>351</Hsp_hit-from>
      <Hsp_hit-to>580</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>244</Hsp_align-len>
      <Hsp_qseq>EVLGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQE-SQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLL---------------------ASADPF--------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNEDEDI---NEQIQNAAFMYPPNPWKEITQDAIDLINNLL</Hsp_qseq>
      <Hsp_hseq>KVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKE-GRFDLSRARFYTAE-------LLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLG-LGYTKAVDWWTLGVLLYEMLTGLPPY-YDEDVPKMYKKILQEPLVFPDG----FDRDAKDLLIGLL</Hsp_hseq>
      <Hsp_midline>+V+G G FG V   + + T    A+K I K    +K E +    E  +L  +  P +V L+  F++PE+++ V+  ++G  L   L  E GR      +F   +       +L AL +LH  ++V+ DLKPEN+LL                        D F        P+++    GY +++D W++GV++Y  L+G  P+  DED+    ++I     ++P        +DA DL+  LL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.3294</Hsp_bit-score>
      <Hsp_score>181</Hsp_score>
      <Hsp_evalue>3.39827e-14</Hsp_evalue>
      <Hsp_query-from>847</Hsp_query-from>
      <Hsp_query-to>1515</Hsp_query-to>
      <Hsp_hit-from>85</Hsp_hit-from>
      <Hsp_hit-to>362</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>126</Hsp_positive>
      <Hsp_gaps>81</Hsp_gaps>
      <Hsp_align-len>291</Hsp_align-len>
      <Hsp_qseq>EVLGSGQFGIVYGGKHRKTGSDVAIKVIDKLR----------FPTKQESQL--------------------------RNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHG-DMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLASAD-----------------------------PFPQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNED--EDINEQIQNAAFMYPPNPWKEITQDAIDLINNLLQVKMRKRYTSEQ</Hsp_qseq>
      <Hsp_hseq>KTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVS--KGKLPER-------EAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMPSN----LSSEARDLISKILVIDPEKRITTQE</Hsp_hseq>
      <Hsp_midline>+ LG G  G V   K+ +TG   AIK++ K +           P    S +                            E+ I++ + H  V+ L  ++E    +++V+E + G ++ + ++S  KG+LPER       +A    ++I+  + + H  NI H DLKPEN+LL   +                               P+++  +  +    D+WS G++++  L+G  PFN+D  + +  ++Q+  +  P N    ++ +A DLI+ +L +   KR T+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>4.0382e-14</Hsp_evalue>
      <Hsp_query-from>811</Hsp_query-from>
      <Hsp_query-to>1608</Hsp_query-to>
      <Hsp_hit-from>161</Hsp_hit-from>
      <Hsp_hit-to>477</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>79</Hsp_identity>
      <Hsp_positive>140</Hsp_positive>
      <Hsp_gaps>91</Hsp_gaps>
      <Hsp_align-len>337</Hsp_align-len>
      <Hsp_qseq>WDISQVYQIFPDEVLGSGQFG---IVYGGKHRKTG-----SDVAIKVIDKLRFPTKQESQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKL--HGDMLEMILSSE-KGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLASADPFPQVIRS------------------------------------------------KQGYNRSLDMWSVGVIVYVSLSGTFPFNEDEDINEQIQNA---AFMYPPNPWKEITQDAIDLINNLLQVKMRKRYTSEQDYQ-TWL--DLRELEVRRSERYVTH------ESDDARWER</Hsp_qseq>
      <Hsp_hseq>WEIT-------NRIVGNGTFGHVLITHNSKERDEDVCYHPENYAVKII-KLK-PNKFDKEAR----ILLRLDHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQ-------ILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGISPFYGDGSERSIIQNAKIGKLNFKLKQWDIVSDNAKSFVKDLLQTDVVKRLNSKQGLKHIWIAKHLSQLERLYYKKILCNNEGPKLESINSDWKR</Hsp_hseq>
      <Hsp_midline>W+I+       + ++G+G FG   I +  K R         + A+K+I KL+ P K + + R    IL  L HP ++ +   F        + + L   GD+   +   +    + E  +  +V Q       IL AL +LH ++IVH DLK +N+LL + +P  +++ +                                                ++GY+   D+WS+GVI ++ L+G  PF  D      IQNA      +    W  ++ +A   + +LLQ  + KR  S+Q  +  W+   L +LE    ++ + +      ES ++ W+R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>6.00266e-14</Hsp_evalue>
      <Hsp_query-from>781</Hsp_query-from>
      <Hsp_query-to>1500</Hsp_query-to>
      <Hsp_hit-from>476</Hsp_hit-from>
      <Hsp_hit-to>761</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>122</Hsp_positive>
      <Hsp_gaps>68</Hsp_gaps>
      <Hsp_align-len>297</Hsp_align-len>
      <Hsp_qseq>RCRTVKFKRTW-DISQVYQIFPD-EVLGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQE-SQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGR-LPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLAS-------------------------------------ADPF-------------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNEDEDINEQIQN---AAFMYPPNPWKEITQDAIDLINNLLQVKMRKR</Hsp_qseq>
      <Hsp_hseq>RLRTKSFSNKFQDIMVGPQSFEKIRLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASE-------VTAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRG-NGHTAAVDWWTLGILIYEMLFGFTPFKGD-NTNETFTNILKNEVSFPNN--NEISRTCKDLIKKLLTKNESKR</Hsp_hseq>
      <Hsp_midline>R RT  F   + DI    Q F    +LG G  G V+  + +KT    A+KV+ K     + +  ++  E  IL + +HP +V L   F++ + +++ ME   G      L + K + + E + +F  ++       +  AL +LH    ++ DLKPEN+LL                                       +D F             P+VIR   G+  ++D W++G+++Y  L G  PF  D + NE   N       +P N   EI++   DLI  LL     KR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>6.0829e-14</Hsp_evalue>
      <Hsp_query-from>847</Hsp_query-from>
      <Hsp_query-to>1515</Hsp_query-to>
      <Hsp_hit-from>124</Hsp_hit-from>
      <Hsp_hit-to>391</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>121</Hsp_positive>
      <Hsp_gaps>71</Hsp_gaps>
      <Hsp_align-len>281</Hsp_align-len>
      <Hsp_qseq>EVLGSGQFGIVYGGKHRKTGSDVAIKVID---------------------------KLRFPTKQESQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHG-DMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLASADPF----------------------------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNEDED--INEQIQNAAFMYPPNPWKEITQDAIDLINNLLQVKMRKRYTSEQ</Hsp_qseq>
      <Hsp_hseq>ETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPPPKNEQDVLERQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYII--QHGSIREH-------QARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKIKQGKVEYP----QHLSIEVISLLSKMLVVDPKRRATLKQ</Hsp_hseq>
      <Hsp_midline>E +G+G  G V   KHR T    A+K+++                           KL     ++ +   E ++ Q L+HP +  L  M       +++ E + G  +L+ I+  + G + E        QA +  R I  AL +LH  NIVH DLK EN++++ +                               P+++++       +D+WS GV+++V + G  PF+++    ++E+I+     YP    + ++ + I L++ +L V  ++R T +Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>6.87463e-14</Hsp_evalue>
      <Hsp_query-from>847</Hsp_query-from>
      <Hsp_query-to>1449</Hsp_query-to>
      <Hsp_hit-from>828</Hsp_hit-from>
      <Hsp_hit-to>1053</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>238</Hsp_align-len>
      <Hsp_qseq>EVLGSGQFGIVYGGKHRKTGSDVAIKVIDK---LRFPTKQESQLRNEVAILQS-LHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLASADPF-----------------------------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNEDEDINEQIQNAAF----MYPPNPWKEITQ</Hsp_qseq>
      <Hsp_hseq>KVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGG--DLMWHVQNQRLSVRRAKFYAAE-------VLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILK-EQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDE--DEVFNAILTDEPLYPIDMAGEIVQ</Hsp_hseq>
      <Hsp_midline>+VLG G FG V   K + T    AIKV+ K   ++    + ++   +V +L +   HP + NL   F+T  R++  ME + G   +++   +  RL  R  KF   +       +L+AL++ H   +++ DLK EN+LL                                   P++++ +Q Y +++D W+ GV++Y  L    PF+ D++  +++ NA      +YP +   EI Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>8.15162e-14</Hsp_evalue>
      <Hsp_query-from>853</Hsp_query-from>
      <Hsp_query-to>1515</Hsp_query-to>
      <Hsp_hit-from>13</Hsp_hit-from>
      <Hsp_hit-to>283</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>118</Hsp_positive>
      <Hsp_gaps>74</Hsp_gaps>
      <Hsp_align-len>283</Hsp_align-len>
      <Hsp_qseq>LGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQESQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALR---HLHFKNIVHCDLKPENVL-------------LASADP----------------FPQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNEDEDINEQIQ-----------------------NAAFMYPPNPWKEI-------TQDAIDLINNLLQVKMRKRYTSEQ</Hsp_qseq>
      <Hsp_hseq>VGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNVIELIDIFMAYDNLNLVLEFLPTD-LEVVI---------KDKSILFTPADIKA-WMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVI-FAELMLRIPYLPGQNDVDQMEVTFRALGTPTDRDWPEVSSFMTYNKLQIYPPPSRDELRKRFIAASEYALDFMCGMLTMNPQKRWTAVQ</Hsp_hseq>
      <Hsp_midline>+G G + +VY G    TG  +AIK I    F    +     EV  LQ + HP V+ L  +F   + + +V+E L  D LE+++         ++   L T A  +   +L+ LR   H H   I+H DLKP N+L             LA A P                 P+++   + Y  ++D+WSVGVI +  L    P+   ++  +Q++                       N   +YPP    E+       ++ A+D +  +L +  +KR+T+ Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.7886</Hsp_bit-score>
      <Hsp_score>177</Hsp_score>
      <Hsp_evalue>8.99355e-14</Hsp_evalue>
      <Hsp_query-from>847</Hsp_query-from>
      <Hsp_query-to>1380</Hsp_query-to>
      <Hsp_hit-from>1179</Hsp_hit-from>
      <Hsp_hit-to>1384</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>215</Hsp_align-len>
      <Hsp_qseq>EVLGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQES------QLRNEVAILQSLHHPGVVNLQSMFETPERVF-VVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLL---------------ASADPF---------------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNEDE</Hsp_qseq>
      <Hsp_hseq>EMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLG-FENKNNIYSLFLEYVAGGSVGSLIRMY-GRFDEPLIKHLTTQ-------VLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLE</Hsp_hseq>
      <Hsp_midline>E++G G FG VY   +  TG  +A+K ++  ++ ++ E+       LR+EV+ L+ L H  +V     FE    ++ + +E + G  +  ++    GR  E   K L TQ       +L  L +LH K I+H D+K +N+LL                S D +               P+++ +KQGY+  +D+WS+G IV    +G  P++  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.4034</Hsp_bit-score>
      <Hsp_score>176</Hsp_score>
      <Hsp_evalue>1.10809e-13</Hsp_evalue>
      <Hsp_query-from>811</Hsp_query-from>
      <Hsp_query-to>1368</Hsp_query-to>
      <Hsp_hit-from>17</Hsp_hit-from>
      <Hsp_hit-to>220</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>216</Hsp_align-len>
      <Hsp_qseq>WDISQVYQIFPDEVLGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQESQLRNEVAILQSLHH-PGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLA--------------------------SADPF---PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPF</Hsp_qseq>
      <Hsp_hseq>MDVSSLFKR--TEVIGRGKFGVVYKGYNVKTGRVYAIKVLN-LDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLL--RPGKIDEKYIGVIM-------RELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPY</Hsp_hseq>
      <Hsp_midline> D+S +++    EV+G G+FG+VY G + KTG   AIKV++ L   + +   ++ E+  L SL     +      +     ++++ME   G  L  +L    G++ E+    ++       R +LVAL+ +H  N++H D+K  NVL+                           +  P+   P+VI     Y+  +D+WS+G+  Y   +G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>1.77613e-13</Hsp_evalue>
      <Hsp_query-from>847</Hsp_query-from>
      <Hsp_query-to>1377</Hsp_query-to>
      <Hsp_hit-from>348</Hsp_hit-from>
      <Hsp_hit-to>545</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>207</Hsp_align-len>
      <Hsp_qseq>EVLGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQE-SQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLL---------------------ASADPF--------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNED</Hsp_qseq>
      <Hsp_hseq>KVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHE-GRFSLARSRFYIAE-------LLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLG-QGYTKTVDWWTLGILLYEMMTGLPPYYDE</Hsp_hseq>
      <Hsp_midline>+V+G G FG V   + + T    A+K + K    +K E +    E  +L  +  P +V L+  F++PE++++V+  ++G  L   L  E GR     ++F + +       +L AL  LH  ++++ DLKPEN+LL                        D F        P+++   QGY +++D W++G+++Y  ++G  P+ ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>2.10285e-13</Hsp_evalue>
      <Hsp_query-from>850</Hsp_query-from>
      <Hsp_query-to>1377</Hsp_query-to>
      <Hsp_hit-from>46</Hsp_hit-from>
      <Hsp_hit-to>255</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>218</Hsp_align-len>
      <Hsp_qseq>VLGSGQFGIVYGG--KHRKTGSD--------VAIKVI--DKLRFPTKQESQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLASADPF-----------------------------PQVIRSKQGYN-RSLDMWSVGVIVYVSLSGTFPFNED</Hsp_qseq>
      <Hsp_hseq>TLGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRKEVKIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQ-KKRRLKEMNACRLFSQ-------LISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVNEFCSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPWDDD</Hsp_hseq>
      <Hsp_midline> LG G+FG V  G  K+    S+        VAIK+I  D +    ++E ++  E+  L+ L HP +V L+ + +    + +V+E   G      +  +K RL E N   L +Q       ++  + ++H K +VH DLK EN+LL   +                               P+++ S + Y  R  D+WS GVI+Y  L+G  P+++D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>2.79197e-13</Hsp_evalue>
      <Hsp_query-from>847</Hsp_query-from>
      <Hsp_query-to>1506</Hsp_query-to>
      <Hsp_hit-from>103</Hsp_hit-from>
      <Hsp_hit-to>367</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>122</Hsp_positive>
      <Hsp_gaps>71</Hsp_gaps>
      <Hsp_align-len>278</Hsp_align-len>
      <Hsp_qseq>EVLGSGQFGIVYGGKHRKTGSDVAIKVIDKLR---------FPT-KQESQLRN-----------------EVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHG-DMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLASADPF----------------------------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNEDED--INEQIQNAAFMYPPNPWKEITQDAIDLINNLLQVKMRKRYT</Hsp_qseq>
      <Hsp_hseq>ETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESEILERQKRLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYII--QHGSLKEHH-------ARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYP----SHLSIEVISLLTRMIVVDPLRRAT</Hsp_hseq>
      <Hsp_midline>E +G+G  G V   KHR+T     IK++++            P+ K ES++                   E ++ Q L+HP +  L  M       +++ E + G  +L+ I+  + G L E +       A +  R I  AL++LH  NIVH DLK EN++++S+                               P++++++      +D+WS G+++YV + G  PF+++    ++E+I+     YP      ++ + I L+  ++ V   +R T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.5514</Hsp_bit-score>
      <Hsp_score>166</Hsp_score>
      <Hsp_evalue>5.17584e-13</Hsp_evalue>
      <Hsp_query-from>808</Hsp_query-from>
      <Hsp_query-to>1338</Hsp_query-to>
      <Hsp_hit-from>6</Hsp_hit-from>
      <Hsp_hit-to>213</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>57</Hsp_gaps>
      <Hsp_align-len>221</Hsp_align-len>
      <Hsp_qseq>TWDISQVYQIFPDEVLGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQESQLRNEVAILQSLHHPGVVNLQSM-----FETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLAS----------------------ADP-----------------FPQVIRSKQGYNRSLDMWSVGVIV</Hsp_qseq>
      <Hsp_hseq>VYNISSDFQL--KSLLGEGAYGVVCSATHKPTGEIVAIKKIEPFDKPLFALRTLR-EIKILKHFKHENIITIFNIQRPDSFENFNEVYIIQELMQTD-LHRVISTQ--MLSDDHIQYFIYQTLR-------AVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCIL</Hsp_hseq>
      <Hsp_midline> ++IS  +Q+    +LG G +G+V    H+ TG  VAIK I+    P      LR E+ IL+   H  ++ + ++     FE    V+++ E +  D L  ++S++   L + + ++ + Q  R       A++ LH  N++H DLKP N+L+ S                      ++P                  P+V+ +   Y+R++D+WS G I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>2.35692e-12</Hsp_evalue>
      <Hsp_query-from>751</Hsp_query-from>
      <Hsp_query-to>1422</Hsp_query-to>
      <Hsp_hit-from>17</Hsp_hit-from>
      <Hsp_hit-to>296</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>118</Hsp_positive>
      <Hsp_gaps>58</Hsp_gaps>
      <Hsp_align-len>281</Hsp_align-len>
      <Hsp_qseq>LMPGKSPSASRCR-TVKFKRTWDISQVYQIFPD----EVLGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQESQLR-------NEVAILQSLHHPGVVNLQSMFETPE--RVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRG-RRILVALRHLHFKNIVHCDLKPENVLLASADPF--------------------------------------PQVIRSKQGYNRS--LDMWSVGVIVYVSLSGTFPFNEDEDIN--EQIQNAAFMYP</Hsp_qseq>
      <Hsp_hseq>LYNNASNSSSRIKETRKVKLLYNPLTKRQILNNFEILATLGNGQYGKVKLARDLGTGALVAIKILNRFEKRSGYSLQLKVENPRVNQEIEVMKRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVKWC-PENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPFNANSGLELFDSIINKPLEFP</Hsp_hseq>
      <Hsp_midline>L    S S+SR + T K K  ++     QI  +      LG+GQ+G V   +   TG+ VAIK++++    +    QL+        E+ +++  HH  VV L  +   PE  +V++V+E      ++      K  +       L  Q SR+    ++  L +LH + I H D+KP N+L++S                                          P++  +++ Y+ S  +D+WS+GV +Y  L G  PFN +  +   + I N    +P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>2.38826e-12</Hsp_evalue>
      <Hsp_query-from>853</Hsp_query-from>
      <Hsp_query-to>1485</Hsp_query-to>
      <Hsp_hit-from>88</Hsp_hit-from>
      <Hsp_hit-to>320</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>246</Hsp_align-len>
      <Hsp_qseq>LGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPT-KQESQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKL-HGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLASADPF-----------------------------PQVIRSKQ-GYNRSLDMWSVGVIVYVSLSGTFPFNEDEDIN---EQIQNAAFMYPPNPWKEITQDAIDLINNLLQV</Hsp_qseq>
      <Hsp_hseq>LGEGGFARCFQIKD-DSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELL--KRRKVLTEPEVRFFTTQ-------ICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPF-QARDVNTIYERIKCRDFSFPRD--KPISDEGKILIRDILSL</Hsp_hseq>
      <Hsp_midline>LG G F   +  K   +G   A K + K    + K   +L +E+ I +S+ HP +V     FE    V++++E   +G ++E++    +  L E   +F  TQ       I  A++++H + ++H DLK  N+   S                                 P+V+  K  G++  +D+WS+GV++Y  L G  PF +  D+N   E+I+   F +P +  K I+ +   LI ++L +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>3.41578e-12</Hsp_evalue>
      <Hsp_query-from>820</Hsp_query-from>
      <Hsp_query-to>1383</Hsp_query-to>
      <Hsp_hit-from>5</Hsp_hit-from>
      <Hsp_hit-to>216</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>219</Hsp_align-len>
      <Hsp_qseq>SQVYQIFPDEVLGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQESQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLL-----------ASADPF------------------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGT--FPFNEDED</Hsp_qseq>
      <Hsp_hseq>SQFKQL---EKLGNGTYATVYKGLNKTTGVYVALKEV-KLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQ---LLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEE</Hsp_hseq>
      <Hsp_midline>SQ  Q+   E LG+G +  VY G ++ TG  VA+K + KL       S    E+++++ L H  +V L  +  T  ++ +V E +  D+ + + S   G  P      LV     +   +L  L   H   I+H DLKP+N+L+             A  F                  P V+   + Y+ S+D+WS G I+   ++G   FP   DE+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>1.51203e-11</Hsp_evalue>
      <Hsp_query-from>808</Hsp_query-from>
      <Hsp_query-to>1515</Hsp_query-to>
      <Hsp_hit-from>6</Hsp_hit-from>
      <Hsp_hit-to>306</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>129</Hsp_positive>
      <Hsp_gaps>87</Hsp_gaps>
      <Hsp_align-len>312</Hsp_align-len>
      <Hsp_qseq>TWDISQVYQIFPDEVLGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQESQLRNEVAILQSLH-HPGVVNLQSM-----FETPERVFVVMEKLHGDMLEMILSSEKG--RLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLL------------------ASADP------------------FPQVIRSKQGYNRSLDMWSVGVIVYVSLSGT--FPFNED----------------EDIN--------EQIQNAAFMYPPNPWK------EITQDAIDLINNLLQVKMRKRYTSEQ</Hsp_qseq>
      <Hsp_hseq>TFDIPSQYKLV--DLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRTIR-EIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQ-------ILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIANLP-MRPPLPWETVWSKTDLNPDMIDLLDKMLQFNPDKRISAAE</Hsp_hseq>
      <Hsp_midline>T+DI   Y++   +++G G +G V    H+ +G  VAIK I            +R E+ +L+  H H  ++++         +    V++V E +  D+ ++I +   G   L + + ++   Q       IL AL+ +H   ++H D+KP N+LL                  +S+D                    P+++ + Q Y  ++D+WS G I+   +SG   FP  +                 ED N        E I N   M PP PW+      ++  D IDL++ +LQ    KR ++ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>4.79285e-11</Hsp_evalue>
      <Hsp_query-from>820</Hsp_query-from>
      <Hsp_query-to>1374</Hsp_query-to>
      <Hsp_hit-from>15</Hsp_hit-from>
      <Hsp_hit-to>219</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>215</Hsp_align-len>
      <Hsp_qseq>SQVYQIFPDEVLGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQESQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILS-SEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLASA--------------------DPF--------PQVIRSK-QGYNRSLDMWSVGVIVYVSLSGTFPFNE</Hsp_qseq>
      <Hsp_hseq>SKLYSI--QSCIGRGNFGDVYKAVDRVTQEIVAIKVVN-LEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHE-------VTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPPLSK</Hsp_hseq>
      <Hsp_midline>S++Y I     +G G FG VY    R T   VAIKV++ L    +    L  E+  L  L  P + N  +       +++VME   G     +L  S    LPE    F++ +       + + L++LH +  +H D+K  N+LL                       D F        P+V+  +  GYN   D+WS+G+  Y  L G  P ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>4.83964e-11</Hsp_evalue>
      <Hsp_query-from>847</Hsp_query-from>
      <Hsp_query-to>1377</Hsp_query-to>
      <Hsp_hit-from>364</Hsp_hit-from>
      <Hsp_hit-to>586</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>66</Hsp_gaps>
      <Hsp_align-len>233</Hsp_align-len>
      <Hsp_qseq>EVLGSGQFGIVYGGK-----------------HRKTGSDVAIKVIDKLRFPTKQESQLRNEVAILQSLHHPGVVN-LQSMFETPERVFVVMEKLHG----DMLEMILSSEKGR----LPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLAS--------------------------ADPF---PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPF-NED</Hsp_qseq>
      <Hsp_hseq>EKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQPKKQ--LIMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQ-------GLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQK-GYDEKVDVWSLGIMLIEMIEGEPPYLNED</Hsp_hseq>
      <Hsp_midline>E  G G  G VY  K                 HR  G  VAIK I     P KQ   + NE+ ++       +VN L++     E ++V+ME + G    D+L+ +  S  G     L E    ++V +  +        L+ LH K I+H D+K +N+LL S                            P+   P+++  K GY+  +D+WS+G+++   + G  P+ NED</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YFL033C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:69115:74427:-1 gene:YFL033C transcript:YFL033C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM15 description:Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase [Source:SGD;Acc:S000001861]</Hit_def>
  <Hit_accession>YFL033C</Hit_accession>
  <Hit_len>1770</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>6.46144e-11</Hsp_evalue>
      <Hsp_query-from>853</Hsp_query-from>
      <Hsp_query-to>1260</Hsp_query-to>
      <Hsp_hit-from>800</Hsp_hit-from>
      <Hsp_hit-to>929</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>138</Hsp_align-len>
      <Hsp_qseq>LGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTK-QESQLRNEVAILQ-SLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLASA</Hsp_qseq>
      <Hsp_hseq>ISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDKPYVARLFASFQNKDNLFLVMEYLPGGDLATLIKM-MGYLPDQWAKQYLTE-------IVVGVNDMHQNGIIHHDLKPENLLIDNA</Hsp_hseq>
      <Hsp_midline>+  G +G VY  + + TG   AIKV+ K     K Q + +++E AI+      P V  L + F+  + +F+VME L G  L  ++    G LP++  K  +T+       I+V +  +H   I+H DLKPEN+L+ +A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>1.95014e-10</Hsp_evalue>
      <Hsp_query-from>850</Hsp_query-from>
      <Hsp_query-to>1365</Hsp_query-to>
      <Hsp_hit-from>226</Hsp_hit-from>
      <Hsp_hit-to>421</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>201</Hsp_align-len>
      <Hsp_qseq>VLGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQESQLRNEVAILQSLHHPGVVNLQSMFETPER--VFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLL-------------------ASADPF--------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFP</Hsp_qseq>
      <Hsp_hseq>ILGEGAGGSVSKCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQFNRSFQSEYIVRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKN----LLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVSGEAVNSLATTFTGTSFYMAPERIQG-QPYSVTSDVWSLGLTILEVANGKFP</Hsp_hseq>
      <Hsp_midline>+LG G  G V   K +      A+KVI+ L    + + Q+  E+   +S     +V    MF   E   +++ ME + G  L+ I  +    L ER  +       +    +L  L +LH K ++H D+KP+N+LL                   + A  F        P+ I+  Q Y+ + D+WS+G+ +    +G FP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>2.93104e-10</Hsp_evalue>
      <Hsp_query-from>853</Hsp_query-from>
      <Hsp_query-to>1251</Hsp_query-to>
      <Hsp_hit-from>1272</Hsp_hit-from>
      <Hsp_hit-to>1398</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>135</Hsp_align-len>
      <Hsp_qseq>LGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQE--SQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLL</Hsp_qseq>
      <Hsp_hseq>IGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAALL--EHGRIEDE----MVTQV--YTLQLLEGLAYLHESGIVHRDVKPENILL</Hsp_hseq>
      <Hsp_midline>+G G FG VY       G  +A+K I+     + Q+    ++ E+++L+ L+HP +V+   +    ++V + ME   G  L  +L  E GR+ +     +VTQ      ++L  L +LH   IVH D+KPEN+LL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>2.9543e-10</Hsp_evalue>
      <Hsp_query-from>853</Hsp_query-from>
      <Hsp_query-to>1401</Hsp_query-to>
      <Hsp_hit-from>189</Hsp_hit-from>
      <Hsp_hit-to>391</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>216</Hsp_align-len>
      <Hsp_qseq>LGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQE----SQLRNEVAILQSLHHPGVVNLQS-MFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLASADPF----------------------------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNEDEDINEQIQ</Hsp_qseq>
      <Hsp_hseq>VGEGTYGKVYKAKNTNTEKLVALK---KLRLQGEREGFPITSIR-EIKLLQSFDHPNVSTIKEIMVESQKTVYMIFEYADNDLSGLLLNKE--------VQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKMNSRADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNEL-EQIE</Hsp_hseq>
      <Hsp_midline>+G G +G VY  K+  T   VA+K   KLR   ++E    + +R E+ +LQS  HP V  ++  M E+ + V+++ E    D+  ++L+ E         +   +Q     +++L+ + +LH   I+H D+K  N+L+ +                                P+++     Y   +DMW  G ++    + T  F    ++ EQI+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>3.08606e-10</Hsp_evalue>
      <Hsp_query-from>853</Hsp_query-from>
      <Hsp_query-to>1368</Hsp_query-to>
      <Hsp_hit-from>626</Hsp_hit-from>
      <Hsp_hit-to>814</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>203</Hsp_align-len>
      <Hsp_qseq>LGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQESQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRG--RRILVALRHLHFKNIVHCDLKPENVLLAS--------------------------ADPF---PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPF</Hsp_qseq>
      <Hsp_hseq>IGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKE--LIINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEG-----------GSLTDVVTHCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTMVGTPYWMAPEVV-SRKEYGPKVDIWSLGIMIIEMIEGEPPY</Hsp_hseq>
      <Hsp_midline>+G G  G VY      T   VAIK ++  + P K+   + NE+ +++   HP +VN    +     ++V+ME + G           G L +  T  ++T+       R  L  L  LH K ++H D+K +N+LL+                             P+   P+V+ S++ Y   +D+WS+G+++   + G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>3.70271e-10</Hsp_evalue>
      <Hsp_query-from>835</Hsp_query-from>
      <Hsp_query-to>1515</Hsp_query-to>
      <Hsp_hit-from>12</Hsp_hit-from>
      <Hsp_hit-to>286</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>70</Hsp_gaps>
      <Hsp_align-len>286</Hsp_align-len>
      <Hsp_qseq>IFPDEVLGSGQFGIVYGGKHRKTGSDV-AIKVIDKLRFPTKQESQL----RNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLL--------------ASADP--------------------------------FPQVIRSKQ-GYNRSLDMWSVGVIVYVSLSGTFPFNEDEDINEQIQNAAFMYPPNPWKEITQDA-------IDLINNLLQVKMRKRYTSEQ</Hsp_qseq>
      <Hsp_hseq>IFKEE-LGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLH-KMGTFNDIWTRHFTAQ-------LIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQCGYGS--DIWALGCMIYQFVQGQPPFRGENELKTFEKIVALDYPWGPNNRINNSTSPINPLVINLVQKILVIEVNERISLEQ</Hsp_hseq>
      <Hsp_midline>IF +E LG G +  V+    +K+ + + AIKV  K     + + +     +N + +L   HH G++ L   F   E ++ V++   G  L  +L  + G   +  T+    Q       ++ AL  +H   I+H DLKPENVLL              A+ DP                                 P+++   Q GY    D+W++G ++Y  + G  PF  + ++    +  A  YP  P   I           I+L+  +L +++ +R + EQ</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>4.25404e-10</Hsp_evalue>
      <Hsp_query-from>787</Hsp_query-from>
      <Hsp_query-to>1356</Hsp_query-to>
      <Hsp_hit-from>9</Hsp_hit-from>
      <Hsp_hit-to>213</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>217</Hsp_align-len>
      <Hsp_qseq>RTVKFKRTWDISQVYQIFPDEVLGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQESQLRNEVAILQSLHHPGVVNLQSMFETP-ERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLAS--------------ADP------------FPQVIRSKQGYNRSLDMWSVGVIVYVSLSG</Hsp_qseq>
      <Hsp_hseq>RTQIFGTVFEITNRYNDL--NPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLSPLEDIYFVTE-LQGTDLHRLLQTRP--LEKQFVQYFLYQ-------ILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEG</Hsp_hseq>
      <Hsp_midline>RT  F   ++I+  Y       +G G FG+V       T   VAIK I K         +   E+ +L+ L H  ++ LQ +F +P E ++ V E L G  L  +L +    L ++  ++ + Q       IL  L+++H   ++H DLKP N+L+                 DP             P+++ + Q Y+  +D+WS G I    + G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>5.72186e-10</Hsp_evalue>
      <Hsp_query-from>850</Hsp_query-from>
      <Hsp_query-to>1380</Hsp_query-to>
      <Hsp_hit-from>219</Hsp_hit-from>
      <Hsp_hit-to>419</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>209</Hsp_align-len>
      <Hsp_qseq>VLGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQESQLRNEVAILQSLHHPGVVNLQSMF--ETPERVFVVMEKLHGDMLEMI---LSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLASADPF---------------------------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNEDE</Hsp_qseq>
      <Hsp_hseq>ILGEGAGGSVAKCRLKNGKKVFALKTINTMNTDPEYQKQIFRELQFNKSFKSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISER-------VIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFGVSGEAVNSLAMTFTGTSFYMAPERIQG-QPYSVTCDVWSLGLTLLEVAGGRFPFESDK</Hsp_hseq>
      <Hsp_midline>+LG G  G V   + +      A+K I+ +    + + Q+  E+   +S     +V    MF  E    +++ ME + G  LE     L    GR+ ER          +    +L  L +LH + ++H D+KP+N+LL                                 P+ I+  Q Y+ + D+WS+G+ +     G FPF  D+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>1.7028e-09</Hsp_evalue>
      <Hsp_query-from>853</Hsp_query-from>
      <Hsp_query-to>1533</Hsp_query-to>
      <Hsp_hit-from>1102</Hsp_hit-from>
      <Hsp_hit-to>1354</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>119</Hsp_positive>
      <Hsp_gaps>58</Hsp_gaps>
      <Hsp_align-len>269</Hsp_align-len>
      <Hsp_qseq>LGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPT------KQESQLRNEVAILQSLH---HPGVVNLQSMFETPERVFVVMEKLHG-----DMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLAS----------------ADPF-----------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNEDEDINEQIQNAAFMYPPNPWKEITQDAIDLINNLLQVKMRKRYTSEQ-DYQTWL</Hsp_qseq>
      <Hsp_hseq>MGEGAYGKVNLCIHKKNRYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKKPHENILRLLDFFED-DDYYYIETPVHGETGCIDLFDLI---------EFKTNMTEFEAKLIFKQVVAGIKHLHDQGIVHRDIKDENVIVDSKGFVKIIDFGSAAYVKSGPFDVFVGTIDYAAPEVLGGNPYEGQPQDIWAIGILLYTVVFKENPFYNIDEILE--GDLKF----NNAEEVSEDCIELIKSILNRCVPKRPTIDDINNDKWL</Hsp_hseq>
      <Hsp_midline>+G G +G V    H+K    V IK+I K R         ++   + +E+ I+ +L+   H  ++ L   FE  +  + +   +HG     D+ ++I         E  T     +A    ++++  ++HLH + IVH D+K ENV++ S                + PF           P+V+       +  D+W++G+++Y  +    PF   ++I E   +  F    N  +E+++D I+LI ++L   + KR T +  +   WL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.5362</Hsp_bit-score>
      <Hsp_score>140</Hsp_score>
      <Hsp_evalue>2.12519e-09</Hsp_evalue>
      <Hsp_query-from>904</Hsp_query-from>
      <Hsp_query-to>1377</Hsp_query-to>
      <Hsp_hit-from>588</Hsp_hit-from>
      <Hsp_hit-to>772</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>195</Hsp_align-len>
      <Hsp_qseq>GSDVAIKVIDKLRFPTKQESQLRNEVAILQSLHHPGVVN-LQSMFETPERVFVVMEKLHG----DMLEMILSSEKGRLP--ERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLAS--------------------------ADPF---PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPF-NED</Hsp_qseq>
      <Hsp_hseq>GDKVAIKQMVLSKQPRKE--LIVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIV-------RETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQRE-YDEKIDVWSLGIMTIEMLEGEPPYLNED</Hsp_hseq>
      <Hsp_midline>G  VAIK +   + P K+   + NE+ +++   H  +VN L++   T + ++VVME + G    D++E   +++    P  E    ++V       R     L+ LH K+I+H D+K +NVLL +                            P+   P+V++ ++ Y+  +D+WS+G++    L G  P+ NED</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>2.14509e-09</Hsp_evalue>
      <Hsp_query-from>976</Hsp_query-from>
      <Hsp_query-to>1647</Hsp_query-to>
      <Hsp_hit-from>86</Hsp_hit-from>
      <Hsp_hit-to>349</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>265</Hsp_align-len>
      <Hsp_qseq>EVAILQSLHHPGVVNLQSMFE----TPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLASADPF-----------------------------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNEDEDINEQIQNAAFMYPPNPWKEI--TQDAIDLINNLLQVKMRKRYTSEQDYQTWLDLRELEVRRSER-----YVTHESDDA-RWERHAAECGLAYPTHL</Hsp_qseq>
      <Hsp_hseq>ELEILQNIRHPNLVTLEFFFESHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGIAKVCDFGSAQRLDDNTELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQ-PLFKGDSANSQLEEIAKLLGRFPKSSIKNSQELQDSLNDQKFKKFMHWFPSIEFFDVEFLLKVLTYDATERCDARQLMAHEFFDALRNETYFLPRGSSMPVHL</Hsp_hseq>
      <Hsp_midline>E+ ILQ++ HP +V L+  FE    T +   +  +    + +   LSSE     +  +K           +IL AL  LH  +I H DLKP N+L+  +                                P+++ + + Y   +D+WS+G I+   + G  P  + +  N Q++  A +    P   I  +Q+  D +N+    K    + S + +     L+ L    +ER      + HE  DA R E +    G + P HL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>3.39273e-09</Hsp_evalue>
      <Hsp_query-from>853</Hsp_query-from>
      <Hsp_query-to>1251</Hsp_query-to>
      <Hsp_hit-from>1040</Hsp_hit-from>
      <Hsp_hit-to>1166</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>LGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQES---QLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLL</Hsp_qseq>
      <Hsp_hseq>IGGGTFGQVYSAINLENGEILAVKEI-KIHDTTTMKKIFPLIKEEMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEYCEGGSLASLL--DHGRIEDE----MVTQVYTF--ELLEGLAYLHQSGVVHRDIKPENILL</Hsp_hseq>
      <Hsp_midline>+G G FG VY   + + G  +A+K I K+   T  +     ++ E+ +L+ L+HP +V    +    ++V + ME   G  L  +L  + GR+ +     +VTQ       +L  L +LH   +VH D+KPEN+LL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>4.87704e-09</Hsp_evalue>
      <Hsp_query-from>853</Hsp_query-from>
      <Hsp_query-to>1479</Hsp_query-to>
      <Hsp_hit-from>47</Hsp_hit-from>
      <Hsp_hit-to>268</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>59</Hsp_gaps>
      <Hsp_align-len>245</Hsp_align-len>
      <Hsp_qseq>LGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQESQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHG-DMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLL-----ASADPF-----------------------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNEDED-------INEQIQNAAFMYPPNPWKEITQDAIDLINNLL</Hsp_qseq>
      <Hsp_hseq>IGEGSFGKVYLALHRPTHRKVCLKTSDK------NDPNIVREVFYHRQFDFPYITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFA---------QISGAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTRECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEE--------PKYDAKVIPDDARDLISRLL</Hsp_hseq>
      <Hsp_midline>+G G FG VY   HR T   V +K  DK       +  +  EV   +    P +  L  +  T  +V++ +E   G ++ + +LS  +  L E    F          +I  A+ + H  + VH DLK EN+LL     A    F                       P++I  +      +D+WS+GVI+Y  ++G  PF++D++       +NE+        P    K I  DA DLI+ LL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>2.34574e-08</Hsp_evalue>
      <Hsp_query-from>838</Hsp_query-from>
      <Hsp_query-to>1608</Hsp_query-to>
      <Hsp_hit-from>362</Hsp_hit-from>
      <Hsp_hit-to>643</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>53</Hsp_gaps>
      <Hsp_align-len>296</Hsp_align-len>
      <Hsp_qseq>FPDEVLGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQESQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMIL--SSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLASADP----------------------------FPQVIRS----KQGYNRSLDMWSVGVIVYVSLSGTFPFNED--EDINEQIQNAAFMYPPN-PWKEITQDAIDLINNLLQV--KMRKRYTSEQDYQTWLDLRELEVRRSERYVTHESDDARWER</Hsp_qseq>
      <Hsp_hseq>FLDE-LGHGNYGNVSKVLHKPTNVIMATKEV-RLELDEAKFRQILMELEVLHKCNSPYIVDFYGAFFIEGAVYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAF-IANAVIHG---LKELKEQH--NIIHRDVKPTNILCSANQGTVKLCDFGVSGNLVASLAKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYPPETYDNIFSQLSAIVDGPPPRLPSDKFSSDAQDFVSLCLQKIPERRPTYAALTEHPWLVKYRNQDVHMSE-YITE-----RLER</Hsp_hseq>
      <Hsp_midline>F DE LG G +G V    H+ T   +A K + +L     +  Q+  E+ +L   + P +V+    F     V++ ME + G  L+ I   SSE G + E    F +  A   G   L  L+  H  NI+H D+KP N+L ++                                P+ I+S    +  Y    D+WS+G+ +     G +P+  +  ++I  Q+       PP  P  + + DA D ++  LQ   + R  Y +  ++   +  R  +V  SE Y+T      R ER</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>2.97842e-08</Hsp_evalue>
      <Hsp_query-from>853</Hsp_query-from>
      <Hsp_query-to>1368</Hsp_query-to>
      <Hsp_hit-from>30</Hsp_hit-from>
      <Hsp_hit-to>267</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>70</Hsp_gaps>
      <Hsp_align-len>240</Hsp_align-len>
      <Hsp_qseq>LGSGQFGIVYGGKHRKTGSD-VAIKVIDKLRFPTKQE-SQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVT--------QASRRG----------RRILVALRHLHFKNIVHCDLKPENVLLAS-------ADPFPQV-----------------------------------------IRSKQGYNRSLDMWSVGVIVYVSLSGTFPF</Hsp_qseq>
      <Hsp_hseq>IGKGSFATVYRGHLTSDKSQHVAIKEVSRAKLKNKKLLENLEIEIAILKKIKHPHIVGLIDCERTSTDFYLIMEYCALGDLTFLLKRRKELM--ENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVVFEMCCGTPPF</Hsp_hseq>
      <Hsp_midline>+G G F  VY G      S  VAIK + + +   K+    L  E+AIL+ + HP +V L     T    +++ME      L  +L   K  +   N   L T          +  G          +++  AL+ L  KN+VH D+KP+N+LL++       +  F ++                                         I + Q YN   D+WSVG +V+    GT PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>3.03493e-08</Hsp_evalue>
      <Hsp_query-from>976</Hsp_query-from>
      <Hsp_query-to>1515</Hsp_query-to>
      <Hsp_hit-from>202</Hsp_hit-from>
      <Hsp_hit-to>411</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>54</Hsp_gaps>
      <Hsp_align-len>222</Hsp_align-len>
      <Hsp_qseq>EVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLA-----------------------SADP----------------FPQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPF---NEDEDINEQIQNAAFMYPPNPWKEITQDAIDLINNLLQVKMRKRYTSEQ</Hsp_qseq>
      <Hsp_hseq>ERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLK-EHGTLDETTVSFYAAEIS-------CALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGK-AYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNK--QGPKIPFY-LSEGMKDILNALLKKETAKRWNVDK</Hsp_hseq>
      <Hsp_midline>E +IL  + HP +V L   F    +++++++ + G  L   L  E G L E    F   + S        ALR LH K +V+ DLKPEN LL                          DP                 P+++  K  Y+++ D +S+G ++Y  L G  P+   N    IN+  QN     P  P+  +++   D++N LL+ +  KR+  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>5.92642e-08</Hsp_evalue>
      <Hsp_query-from>847</Hsp_query-from>
      <Hsp_query-to>1539</Hsp_query-to>
      <Hsp_hit-from>845</Hsp_hit-from>
      <Hsp_hit-to>1101</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>122</Hsp_positive>
      <Hsp_gaps>60</Hsp_gaps>
      <Hsp_align-len>274</Hsp_align-len>
      <Hsp_qseq>EVLGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPT------KQESQLRNEVAILQSLH---HPGVVNLQSMFETPERVFVVMEKLHG-----DMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLAS----------------ADPF-----------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFP-FNEDEDINEQIQNAAFMYPPNPWKEITQDAIDLINNLLQVKMRKRYTSEQDYQT-WLDL</Hsp_qseq>
      <Hsp_hseq>QVMGEGAYGKVNLCIHNREHYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKNSQENILKLLDFFED-DDYYYIETPVHGETGSIDLFDVI--EFKKDMVEHEAKLVFKQ-------VVASIKHLHDQGIVHRDIKDENVIVDSHGFVKLIDFGSAAYIKSGPFDVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLYTIIYKENPYYNIDEILEGELRF-------DKSEHVSEECISLIKRILTREVDKRPTIDEIYEDKWLKI</Hsp_hseq>
      <Hsp_midline>+V+G G +G V    H +    V IK+I K R         ++   + +E+ I+ +L+      ++ L   FE  +  + +   +HG     D+ ++I    K  + E   K +  Q       ++ +++HLH + IVH D+K ENV++ S                + PF           P+V+       +  D+W++GV++Y  +    P +N DE +  +++        +  + ++++ I LI  +L  ++ KR T ++ Y+  WL +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>1.10256e-07</Hsp_evalue>
      <Hsp_query-from>847</Hsp_query-from>
      <Hsp_query-to>1251</Hsp_query-to>
      <Hsp_hit-from>356</Hsp_hit-from>
      <Hsp_hit-to>483</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>137</Hsp_align-len>
      <Hsp_qseq>EVLGSGQFGIVYGGKHRKTGSDVAIKVIDKLR-FPTKQESQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKL-HGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLL</Hsp_qseq>
      <Hsp_hseq>KVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQ--LFTEDVTRFYMAEC-------ILAIETIHKLGFIHRDIKPDNILI</Hsp_hseq>
      <Hsp_midline>+V+G G FG V   + + TG   A+K + K   +   Q + ++ E  +L     P VV+L   F+  + ++++ME L  GD++ M++  +     E  T+F + +        ++A+  +H    +H D+KP+N+L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>1.31572e-07</Hsp_evalue>
      <Hsp_query-from>847</Hsp_query-from>
      <Hsp_query-to>1506</Hsp_query-to>
      <Hsp_hit-from>19</Hsp_hit-from>
      <Hsp_hit-to>271</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>120</Hsp_positive>
      <Hsp_gaps>61</Hsp_gaps>
      <Hsp_align-len>267</Hsp_align-len>
      <Hsp_qseq>EVLGSGQFGIVYGGKHRKTGSDV-AIKVIDKLRFPTKQESQLRNE----VAILQSL--HHPGVVNLQSMFETPERVFVVMEKLHG-DMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFK-NIVHCDLKPENVLL-------------------------ASAD-----PF--PQVIRSKQGY--NRSLDMWSVGVIVYVSLSGTFPFN----EDEDINEQIQNAAFMYPPNPWKEITQDAIDLINNLLQVKMRKRYT</Hsp_qseq>
      <Hsp_hseq>DTVGQGAFACVKNAHLQMDPSIILAVKFI---HVPTCKKMGLSDKDITKEVVLQSKCSKHPNVLRLIDCNVSKEYMWIILEMADGGDLFDKI---------EPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRT-DIWSIGILLFVLLTGQTPWELPSLENEDFVFFIENDGNL-NWGPWSKIEFTHLNLLRKILQPDPNKRVT</Hsp_hseq>
      <Hsp_midline>+ +G G F  V     +   S + A+K I     PT ++  L ++      +LQS    HP V+ L     + E +++++E   G D+ + I         E +       A    ++++ A+ +LH +  + H D+KPEN+LL                          S D     P+  P+V+ S++GY  +R+ D+WS+G++++V L+G  P+     E+ED    I+N   +    PW +I    ++L+  +LQ    KR T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YPR111W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:747306:749000:1 gene:YPR111W transcript:YPR111W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF20 description:Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006315]</Hit_def>
  <Hit_accession>YPR111W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>1.40345e-07</Hsp_evalue>
      <Hsp_query-from>853</Hsp_query-from>
      <Hsp_query-to>1260</Hsp_query-to>
      <Hsp_hit-from>175</Hsp_hit-from>
      <Hsp_hit-to>303</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>137</Hsp_align-len>
      <Hsp_qseq>LGSGQFGIVYGGKHRKTGSDVAIKVIDK-LRFPTKQESQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLASA</Hsp_qseq>
      <Hsp_hseq>VGQGGYGQVYLAKKKDSDEICALKILNKKLLFKLNETNHVLTERDILTTTRSDWLVKLLYAFQDPESLYLAMEFVPGGDFRTLLINTRI-LKSGHARFYISE-------MFCAVNALHELGYTHRDLKPENFLIDAT</Hsp_hseq>
      <Hsp_midline>+G G +G VY  K + +    A+K+++K L F   + + +  E  IL +     +V L   F+ PE +++ ME + G     +L + +  L   + +F +++       +  A+  LH     H DLKPEN L+ + </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>1.65889e-07</Hsp_evalue>
      <Hsp_query-from>847</Hsp_query-from>
      <Hsp_query-to>1368</Hsp_query-to>
      <Hsp_hit-from>129</Hsp_hit-from>
      <Hsp_hit-to>337</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>55</Hsp_gaps>
      <Hsp_align-len>219</Hsp_align-len>
      <Hsp_qseq>EVLGSGQFGIVYGGKHRKTGSDVAIKVIDK-LRFPTKQESQLRNEVAILQSLHH-PGVVNLQSMFETPERVFVVMEKL-HGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLL------------------------ASADPF------------------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPF</Hsp_qseq>
      <Hsp_hseq>EQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQKLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLI--KKYGSLNETCARYYASQ-------IIDAVDSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSR-CDIWAFGCILYQMLAGKPPF</Hsp_hseq>
      <Hsp_midline>E LG G +  V     R +G   A+KV+ K      K+   +  E   LQ L+   G+  L   F+    ++ ++E   HGD L +I   + G L E   ++  +Q       I+ A+  LH   I+H D+KPEN+LL                        A   P+                  P+++      +R  D+W+ G I+Y  L+G  PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>1.78552e-07</Hsp_evalue>
      <Hsp_query-from>847</Hsp_query-from>
      <Hsp_query-to>1401</Hsp_query-to>
      <Hsp_hit-from>43</Hsp_hit-from>
      <Hsp_hit-to>251</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>60</Hsp_gaps>
      <Hsp_align-len>227</Hsp_align-len>
      <Hsp_qseq>EVLGSGQFGIVYGGKHRKTGSDVAI-KVIDKLRFPTKQESQLRNEVAILQSLHHPGVVNLQSMF---ETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGR--------RILVALRHL-HFKNIVHCDLKPENVL------------------LASADP-----------FPQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNEDEDINEQIQ</Hsp_qseq>
      <Hsp_hseq>EVVGHGSFGVVFATVIQETNEKVAIKKVLQDKRFKNR-------ELEIMKMLSHINIIDLKYFFYERDSQDEIY----------LNLILEYMPQSLYQRLRHF-VHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVE</Hsp_hseq>
      <Hsp_midline>EV+G G FG+V+    ++T   VAI KV+   RF  +       E+ I++ L H  +++L+  F   ++ + ++          L +IL      L +R   F V Q +   R        ++  +L +L HF N+ H D+KP+N+L                  L   +P            P++I     Y   +D+WS G ++   L G   F  +  I++ ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>3.18139e-07</Hsp_evalue>
      <Hsp_query-from>799</Hsp_query-from>
      <Hsp_query-to>1392</Hsp_query-to>
      <Hsp_hit-from>13</Hsp_hit-from>
      <Hsp_hit-to>241</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>234</Hsp_align-len>
      <Hsp_qseq>FKRTWDISQVYQIFPDEVLGSGQFGIVYGGKHRKTGSD--VAIKVIDKLRFPTKQESQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDML-EMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLA----------------SADPF-----------------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNEDEDINE</Hsp_qseq>
      <Hsp_hseq>FNQDFSVDKRFQLIKE--IGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLR--HFRGHKNITCLYDM-DIVFYPDGSINGLYLYEELMECDMHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQ</Hsp_hseq>
      <Hsp_midline>F + + + + +Q+  +  +G G +GIV   +  +   D  VAIK +  +   T    +   E+ +L+  H  G  N+  +++  + VF     ++G  L E ++  +  ++ +               +IL  L+++H  +++H DLKP N+L+                 S +P                  P+++ S QGY +++D+WS G I+   L G   F   + +N+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>3.32474e-07</Hsp_evalue>
      <Hsp_query-from>850</Hsp_query-from>
      <Hsp_query-to>1251</Hsp_query-to>
      <Hsp_hit-from>184</Hsp_hit-from>
      <Hsp_hit-to>311</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>137</Hsp_align-len>
      <Hsp_qseq>VLGSGQFGIVYGGKHRKTGSDVAIKVIDK-LRFPTKQESQLRNEVAILQSLHH-PGVVNLQSMFETPERVFVVMEKL-HGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLL</Hsp_qseq>
      <Hsp_hseq>VIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLM--KKYGSLDETCARYYAAQ-------IIDAIDYLHSNGIIHRDIKPENILL</Hsp_hseq>
      <Hsp_midline>V+G G +  V       T    A KV++K      K+   +  E   LQ L++ P VV L S F+    ++ ++E   +GD L ++   + G L E   ++   Q       I+ A+ +LH   I+H D+KPEN+LL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>3.54331e-07</Hsp_evalue>
      <Hsp_query-from>844</Hsp_query-from>
      <Hsp_query-to>1251</Hsp_query-to>
      <Hsp_hit-from>63</Hsp_hit-from>
      <Hsp_hit-to>203</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>145</Hsp_align-len>
      <Hsp_qseq>DEVLGSGQFGIVYGGKHRKTGSDVAIKVI----DKLRFPTKQESQLRNEVAILQSLHHPGVVNLQSMF--ETPERVFVVMEKLHGD---MLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLL</Hsp_qseq>
      <Hsp_hseq>DEKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQR----EITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILI</Hsp_hseq>
      <Hsp_midline>DE LG G FG VY G H +T   VA+K I    +K  FP   +     E+ IL+ L+H  ++ L  M    +P+        LH     +L  +++   G L        +        +IL  L ++H    +H D+K  N+L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>5.96143e-07</Hsp_evalue>
      <Hsp_query-from>847</Hsp_query-from>
      <Hsp_query-to>1338</Hsp_query-to>
      <Hsp_hit-from>373</Hsp_hit-from>
      <Hsp_hit-to>560</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>201</Hsp_align-len>
      <Hsp_qseq>EVLGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQESQLRNEVAILQSL---------HHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLASADP----------------------------FPQVIRSKQGYNRSLDMWSVGVIV</Hsp_qseq>
      <Hsp_hseq>DILGQGTFGQVVKCQNLLTKEILAVKVV---KSRTEYLTQSITEAKILELLNQKIDPTNKHH--FLRMYDSFVHKNHLCLVFELLSNNLYELLKQNKFHGLSIQLIRTFTTQ-------ILDSLCVLKESKLIHCDLKPENILLCAPDKPELKIIDFGSSCEEARTVYTYIQSRFYRAPEIILGIP-YSTSIDMWSLGCIV</Hsp_hseq>
      <Hsp_midline>++LG G FG V   ++  T   +A+KV+   +  T+  +Q   E  IL+ L         HH   + +   F     + +V E L  ++ E++  ++   L  +  +   TQ       IL +L  L    ++HCDLKPEN+LL + D                              P++I     Y+ S+DMWS+G IV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>8.11171e-07</Hsp_evalue>
      <Hsp_query-from>745</Hsp_query-from>
      <Hsp_query-to>1338</Hsp_query-to>
      <Hsp_hit-from>10</Hsp_hit-from>
      <Hsp_hit-to>240</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>61</Hsp_gaps>
      <Hsp_align-len>245</Hsp_align-len>
      <Hsp_qseq>QALMPGKSPSASRCRTVKFKRTWDISQVYQIFPDEVLGSGQFGIVYGGKH--RKTGSDVAIKVIDKLRFPTKQESQLRNEVAILQSLH----HPGVVNL---QSMFETP-ERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLL-------------------------ASADPF------------PQVIRSKQGYNRSLDMWSVGVIV</Hsp_qseq>
      <Hsp_hseq>RAINVASNLGAPQQRTIFAKERISIPGYYEII--QFLGKGAYGTVCSVKFKGRSPAARIAVKKISNI---FNKEILLKRAIRELKFMNFFKGHKNIVNLIDLEIVTSSPYDGLYCYQELIDYDLAKVIHSSV--QLSEFHIKYFLYQ-------ILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCIL</Hsp_hseq>
      <Hsp_midline>+A+    +  A + RT+  K    I   Y+I   + LG G +G V   K   R   + +A+K I  +     +E  L+  +  L+ ++    H  +VNL   + +  +P + ++   E +  D+ ++I SS   +L E + K+ + Q       IL  L+++H  +++H DLKP N+L                          ++  P             P+++ S Q Y++S+D+W+VG I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>1.04694e-06</Hsp_evalue>
      <Hsp_query-from>847</Hsp_query-from>
      <Hsp_query-to>1251</Hsp_query-to>
      <Hsp_hit-from>320</Hsp_hit-from>
      <Hsp_hit-to>457</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>147</Hsp_align-len>
      <Hsp_qseq>EVLGSGQFGIVYGGKHRKTGSDVAIK-----VIDKLRFPTKQESQ-----LRNEVAILQSLHHPGVVNLQSMFETPERVFV-VMEKLHG-DMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLL</Hsp_qseq>
      <Hsp_hseq>EVLGKGAFGVVRICQKKNVSSQDGNKSEKLYAVKEFKRRTSESAEKYSKRLTSEFCISSSLHHTNIVTTLDLFQDAKGEYCEVMEYCAGGDLFTLVVAAGKLEYMEADCFF---------KQLIRGVVYMHEMGVCHRDLKPENLLL</Hsp_hseq>
      <Hsp_midline>EVLG G FG+V   + +   S    K      + + +  T + ++     L +E  I  SLHH  +V    +F+  +  +  VME   G D+  +++++ K    E +  F         ++++  + ++H   + H DLKPEN+LL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>1.78164e-06</Hsp_evalue>
      <Hsp_query-from>823</Hsp_query-from>
      <Hsp_query-to>1254</Hsp_query-to>
      <Hsp_hit-from>131</Hsp_hit-from>
      <Hsp_hit-to>286</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>164</Hsp_align-len>
      <Hsp_qseq>QVYQIFPDEVLGSGQFGIVYGGKHRKTGSDVAIKVIDK-----LRFPT-------KQESQLRNEVAILQSLHHPGVVNLQSMFE--TPERVFVVMEKL-HGDML----EMILSSEKGRLPERNTKFLVTQASRR-GRRILVALRHLHFKNIVHCDLKPENVLLA</Hsp_qseq>
      <Hsp_hseq>NTYEIIKE--LGHGQHGKVKLARDILSKQLVAIKIVDRHEKKQRKFFTFIKSSKISENDKIKREIAIMKKCHHKHVVQLIEVLDDLKSRKIYLVLEYCSRGEVKWCPPDCMESDAKG------PSLLSFQETREILRGVVLGLEYLHYQGIIHRDIKPANLLIS</Hsp_hseq>
      <Hsp_midline>  Y+I  +  LG GQ G V   +   +   VAIK++D+      +F T        +  +++ E+AI++  HH  VV L  + +     ++++V+E    G++     + + S  KG         L  Q +R   R +++ L +LH++ I+H D+KP N+L++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>1.81102e-06</Hsp_evalue>
      <Hsp_query-from>1270</Hsp_query-from>
      <Hsp_query-to>1515</Hsp_query-to>
      <Hsp_hit-from>389</Hsp_hit-from>
      <Hsp_hit-to>471</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNED--EDINEQIQNAAFMYPPNPWKEITQDAIDLINNLLQVKMRKRYTSEQ</Hsp_qseq>
      <Hsp_hseq>PEVVKDEH-YSMKVDMWGIGCVLYTMLCGFPPFYDEKIDTLTEKISRGEYTFLKPWWDEISAGAKNAVAKLLELEPSKRYDIDQ</Hsp_hseq>
      <Hsp_midline>P+V++ +  Y+  +DMW +G ++Y  L G  PF ++  + + E+I    + +    W EI+  A + +  LL+++  KRY  +Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>2.60108e-06</Hsp_evalue>
      <Hsp_query-from>853</Hsp_query-from>
      <Hsp_query-to>1368</Hsp_query-to>
      <Hsp_hit-from>421</Hsp_hit-from>
      <Hsp_hit-to>657</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>83</Hsp_gaps>
      <Hsp_align-len>246</Hsp_align-len>
      <Hsp_qseq>LGSGQFGIVYGGKHRKTGSDVAIKVI----DKLRFPTKQESQ--------------------------------------LRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLL--------------ASADPF------------------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPF</Hsp_qseq>
      <Hsp_hseq>IGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNN-YGPFEES----LITNFTRQ---ILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKA-DIWSTGCVVIEMFTGKHPF</Hsp_hseq>
      <Hsp_midline>+GSG FG VY G +  TG  +A+K +    + +  PT    Q                                      L++E+ +L+ LHH  +V      +    + + +E + G  +  +L++  G   E     L+T  +R+   IL+ + +LH KNI+H D+K  N+L+                  P                   P+V++      ++ D+WS G +V    +G  PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.595</Hsp_bit-score>
      <Hsp_score>109</Hsp_score>
      <Hsp_evalue>4.74453e-06</Hsp_evalue>
      <Hsp_query-from>847</Hsp_query-from>
      <Hsp_query-to>1446</Hsp_query-to>
      <Hsp_hit-from>12</Hsp_hit-from>
      <Hsp_hit-to>240</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>43</Hsp_gaps>
      <Hsp_align-len>236</Hsp_align-len>
      <Hsp_qseq>EVLGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQE---SQLRNEVAILQSLHHPGVVNLQSMFET-PERVFVVMEKLHGDMLEMILSSEKGR-LPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLL---------------ASADPF--------------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNEDEDINEQIQNAAFMYPPNP--WKEIT</Hsp_qseq>
      <Hsp_hseq>EKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCK-------GIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIV</Hsp_hseq>
      <Hsp_midline>E +G G +G+VY     + G    +  + K+R  ++ E   S    E+++L+ L    +V L  +  +   ++++V E L  D+   +    K + L     K  + Q  +        + + H   I+H DLKP+N+L+               A   P               P+V+   + Y+  +D WS+G I     +    F+ D +I++  +    +  PN   W +I </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.9802</Hsp_bit-score>
      <Hsp_score>110</Hsp_score>
      <Hsp_evalue>5.47516e-06</Hsp_evalue>
      <Hsp_query-from>1051</Hsp_query-from>
      <Hsp_query-to>1545</Hsp_query-to>
      <Hsp_hit-from>104</Hsp_hit-from>
      <Hsp_hit-to>326</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>78</Hsp_gaps>
      <Hsp_align-len>233</Hsp_align-len>
      <Hsp_qseq>VFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLLAS---------------------ADPF------------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNEDEDI-----------------------NEQIQNAAFMYPPNPWKEITQ-------DAIDLINNLLQVKMRKRYTSEQDYQ-----TWLDLRE</Hsp_qseq>
      <Hsp_hseq>VYLYEELMECDLSQIIRSEQ--RLEDAHFQSFIYQ-------ILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCIL-AELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIPGRSFESILPGANPEALELLKKMLEFDPKKRITVEDALEHPYLSMWHDIDE</Hsp_hseq>
      <Hsp_midline>V++  E +  D+ ++I S +  RL + + +  + Q       IL AL+++H  N++HCDLKP+N+L+ S                      D F            P+++ + Q   +++D+WS G I+   L G  P  E +D                        ++++ N  F +   P +           +A++L+  +L+   +KR T E   +      W D+ E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.3654</Hsp_bit-score>
      <Hsp_score>111</Hsp_score>
      <Hsp_evalue>5.64055e-06</Hsp_evalue>
      <Hsp_query-from>853</Hsp_query-from>
      <Hsp_query-to>1251</Hsp_query-to>
      <Hsp_hit-from>183</Hsp_hit-from>
      <Hsp_hit-to>308</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>134</Hsp_align-len>
      <Hsp_qseq>LGSGQFGIVYGGKHRKTGSDVAIKVIDK-LRFPTKQESQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMILSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVLL</Hsp_qseq>
      <Hsp_hseq>VGQGGYGQVYLARKKDTKEVCALKILNKKLLFKLNETKHVLTERDILTTTRSEWLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINTRC-LKSGHARFYISE-------MFCAVNALHDLGYTHRDLKPENFLI</Hsp_hseq>
      <Hsp_midline>+G G +G VY  + + T    A+K+++K L F   +   +  E  IL +     +V L   F+  + +++ ME + G     +L + +  L   + +F +++       +  A+  LH     H DLKPEN L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.595</Hsp_bit-score>
      <Hsp_score>109</Hsp_score>
      <Hsp_evalue>8.27676e-06</Hsp_evalue>
      <Hsp_query-from>736</Hsp_query-from>
      <Hsp_query-to>1383</Hsp_query-to>
      <Hsp_hit-from>137</Hsp_hit-from>
      <Hsp_hit-to>369</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>53</Hsp_gaps>
      <Hsp_align-len>251</Hsp_align-len>
      <Hsp_qseq>AIRQALMPGKSPSASRCRTVKFKRTWDISQVYQIFPDEVLGSGQFGIVYGGKHRKTGSDVAIKVIDKLRFPTKQESQLRNEVAILQSLHHPGVVNLQSMFETPERVFVVMEKLHGDMLEMI---LSSEKGRLPERNTKFLVTQASRRGRRILVALRHLHFKNIVHCDLKPENVL-----------LASADPF---------------------PQVIRSKQGYNRSLDMWSVGVIVYVSLSGTFPFNEDED</Hsp_qseq>
      <Hsp_hseq>ALRRNLLKDEGVTPGRIRTTR----EDVSPHYN-SQKQTLIKKPLTVFYAIKKFKTEKDG----VEQLHYTGISQSACR-EMALCRELHNKHLTTLVEIFLERKCVHMVYEYAEHDLLQIIHFHSHPEKRMIPPRMVRSIMWQ-------LLDGVSYLHQNWVLHRDLKPANIMVTIDGCVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCI-FAELIGLQPIFKGEE</Hsp_hseq>
      <Hsp_midline>A+R+ L+  +  +  R RT +     D+S  Y     + L      + Y  K  KT  D     +++L +    +S  R E+A+ + LH+  +  L  +F   + V +V E    D+L++I      EK  +P R  + ++ Q       +L  + +LH   ++H DLKP N++           L  A  F                     P+++   + Y  ++D+WSVG I +  L G  P  + E+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1150394701</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054917-RA transcript Note:&quot;Similar to NPAS3 Neuronal PAS domain-containing protein 3 (Homo sapiens)&quot; offset:0 AED:0.13 eAED:0.17 QI:0|0|0|0.71|1|1|7|0|708</Iteration_query-def>
  <Iteration_query-len>2127</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1391606604</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054918-RA transcript Note:&quot;Similar to AKAP6 A-kinase anchor protein 6 (Homo sapiens)&quot; offset:954 AED:0.42 eAED:0.42 QI:954|0.6|0.83|1|0.8|0.66|6|0|286</Iteration_query-def>
  <Iteration_query-len>1815</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1166404170</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054920-RA transcript Note:&quot;Similar to THBS1 Thrombospondin-1 (Homo sapiens)&quot; offset:212 AED:0.12 eAED:0.12 QI:212|0.73|0.85|0.95|0.57|0.55|20|1992|1024</Iteration_query-def>
  <Iteration_query-len>5279</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>104</Statistics_hsp-len>
      <Statistics_eff-space>3686788885</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0000464-RA transcript Note:&quot;Similar to snap25a Synaptosomal-associated protein 25-A (Danio rerio)&quot; offset:0 AED:0.57 eAED:0.57 QI:0|0|0|0.66|0|0|3|472|112</Iteration_query-def>
  <Iteration_query-len>811</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>88</Statistics_hsp-len>
      <Statistics_eff-space>424654594</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0043058-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0|0|3|1426|115</Iteration_query-def>
  <Iteration_query-len>1774</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1134385232</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0017522-RA transcript Note:&quot;Similar to RASGRP3 Ras guanyl-releasing protein 3 (Homo sapiens)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|-1|0|0|-1|0|1|0|73</Iteration_query-def>
  <Iteration_query-len>222</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>46</Statistics_hsp-len>
      <Statistics_eff-space>73093076</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0043056-RA transcript Note:&quot;Similar to FOXG1 Forkhead box protein G1 (Gallus gallus)&quot; offset:0 AED:0.29 eAED:0.33 QI:0|0|0|0.66|0|0|3|0|346</Iteration_query-def>
  <Iteration_query-len>1041</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YNL068C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:495701:498289:-1 gene:YNL068C transcript:YNL068C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FKH2 description:Forkhead family transcription factor; rate-limiting activator of replication origins; evolutionarily conserved regulator of lifespan; binds multiple chromosomal elements with distinct specificities, cell cycle dynamics; positively regulates transcriptional elongation; facilitates clustering, activation of early-firing replication origins; negative role in chromatin silencing at HML and HMR; major role in expression of G2/M phase genes; relocalizes to cytosol under hypoxia [Source:SGD;Acc:S000005012]</Hit_def>
  <Hit_accession>YNL068C</Hit_accession>
  <Hit_len>862</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>109.768</Hsp_bit-score>
      <Hsp_score>273</Hsp_score>
      <Hsp_evalue>8.94719e-27</Hsp_evalue>
      <Hsp_query-from>169</Hsp_query-from>
      <Hsp_query-to>492</Hsp_query-to>
      <Hsp_hit-from>340</Hsp_hit-from>
      <Hsp_hit-to>451</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>112</Hsp_align-len>
      <Hsp_qseq>KPPFSYNALIMMAIRQSPEKRLTLSGIYEYIMHNFPYYRQNKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSSDDVFIG----GRTGKLRRRSAASPRGKLQLA</Hsp_qseq>
      <Hsp_hseq>KPPHSYATMITQAILSSPEGVISLADIYKYISSNYAYYRFAKSGWQNSIRHNLSLNKAFEKVPRRPNEPGKGMKWRISESYQQEFLNKWNTGKVGKIRRGSSVARQLQLHMA</Hsp_hseq>
      <Hsp_midline>KPP SY  +I  AI  SPE  ++L+ IY+YI  N+ YYR  K GWQNSIRHNLSLNK F KVPR  ++PGKG  W +  S    F+     G+ GK+RR S+ + + +L +A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YCR065W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:229310:231004:1 gene:YCR065W transcript:YCR065W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HCM1 description:Forkhead transcription factor; drives S-phase activation of genes involved in chromosome segregation, spindle dynamics, budding; also activates genes involved in respiration, use of alternative energy sources (like proline), NAD synthesis, oxidative stress resistance; key factor in early adaptation to nutrient deficiency and diauxic shift; suppressor of calmodulin mutants with specific SPB assembly defects; ortholog of C. elegans lifespan regulator PHA-4 [Source:SGD;Acc:S000000661]</Hit_def>
  <Hit_accession>YCR065W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>97.8265</Hsp_bit-score>
      <Hsp_score>242</Hsp_score>
      <Hsp_evalue>6.69015e-23</Hsp_evalue>
      <Hsp_query-from>169</Hsp_query-from>
      <Hsp_query-to>435</Hsp_query-to>
      <Hsp_hit-from>109</Hsp_hit-from>
      <Hsp_hit-to>195</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>89</Hsp_align-len>
      <Hsp_qseq>KPPFSYNALIMMAIRQSPEKRLTLSGIYEYIMHNFPYYRQNKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSSDDVFIGGR</Hsp_qseq>
      <Hsp_hseq>KPPYSYATLICLAILQSQEGKLTLSQIYHWIHVHFPYYKQKDASWQNSIRHNLSLNDAFIKTEKSCD--GKGHFWEVRPGAETKFFKGE</Hsp_hseq>
      <Hsp_midline>KPP+SY  LI +AI QS E +LTLS IY +I  +FPYY+Q    WQNSIRHNLSLN  F+K  +  D  GKG++W + P ++  F  G </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YIL131C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:100781:102235:-1 gene:YIL131C transcript:YIL131C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FKH1 description:Forkhead family transcription factor; rate-limiting replication origin activator; evolutionarily conserved lifespan regulator; binds multiple chromosomal elements with distinct specificities, cell cycle dynamics; regulates transcription elongation, chromatin silencing at mating loci, expression of G2/M phase genes; facilitates clustering, activation of early-firing replication origins; binds HML recombination enhancer, regulates donor preference during mating-type switching [Source:SGD;Acc:S000001393]</Hit_def>
  <Hit_accession>YIL131C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>89.7373</Hsp_bit-score>
      <Hsp_score>221</Hsp_score>
      <Hsp_evalue>2.27696e-20</Hsp_evalue>
      <Hsp_query-from>169</Hsp_query-from>
      <Hsp_query-to>489</Hsp_query-to>
      <Hsp_hit-from>303</Hsp_hit-from>
      <Hsp_hit-to>411</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>109</Hsp_align-len>
      <Hsp_qseq>KPPFSYNALIMMAIRQSPEKRLTLSGIYEYIMHNFPYYRQNKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWML-DPSSDDVFIGGRTGKLRR-RSAASPRGKLQL</Hsp_qseq>
      <Hsp_hseq>KPPQSYASMITQAILSTPEGSISLADIYKFISDNYAFYRFSQMAWQNSVRHNLSLNKAFEKVPKRAGQQGKGMNWKISDEVRRDFLNKWNAGKLSKIRRGASVTRQLQL</Hsp_hseq>
      <Hsp_midline>KPP SY ++I  AI  +PE  ++L+ IY++I  N+ +YR ++  WQNS+RHNLSLNK F KVP+     GKG  W + D    D       GKL + R  AS   +LQL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YPR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:733623:736433:-1 gene:YPR104C transcript:YPR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FHL1 description:Regulator of ribosomal protein (RP) transcription; has forkhead associated domain that binds phosphorylated proteins; recruits coactivator Ifh1p or corepressor Crf1p to RP gene promoters; also has forkhead DNA-binding domain though in vitro DNA binding assays give inconsistent results; computational analyses suggest it binds DNA directly at highly active RP genes and indirectly through Rap1p motifs at others; suppresses RNA pol III and splicing factor prp4 mutants [Source:SGD;Acc:S000006308]</Hit_def>
  <Hit_accession>YPR104C</Hit_accession>
  <Hit_len>936</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>2.58249e-14</Hsp_evalue>
      <Hsp_query-from>169</Hsp_query-from>
      <Hsp_query-to>459</Hsp_query-to>
      <Hsp_hit-from>461</Hsp_hit-from>
      <Hsp_hit-to>550</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>98</Hsp_align-len>
      <Hsp_qseq>KPPFSYNALIMMAIRQ-SPEKRLTLSGIYEYIMHNFPYYRQNKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSSDDVFIGGRTGKLRRRS</Hsp_qseq>
      <Hsp_hseq>KPTVSYSAMLTTCIRKYSTAKGMSLSEIYAGIRELFPYYKYCPDGWQSSVRHNLSLNKSFRKVSKE----GKGWLWGL----DEEYIAERERQKKKQS</Hsp_hseq>
      <Hsp_midline>KP  SY+A++   IR+ S  K ++LS IY  I   FPYY+    GWQ+S+RHNLSLNK F KV +     GKG  W L    D+ +I  R  + +++S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>592247552</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

