<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0058600-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.64 eAED:0.65 QI:0|0|0|0.66|1|1|3|0|71</BlastOutput_query-def>
  <BlastOutput_query-len>216</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058600-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.64 eAED:0.65 QI:0|0|0|0.66|1|1|3|0|71</Iteration_query-def>
  <Iteration_query-len>216</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>44</Statistics_hsp-len>
      <Statistics_eff-space>73462676</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058601-RA transcript Note:&quot;Similar to TIGD2 Tigger transposable element-derived protein 2 (Homo sapiens)&quot; offset:0 AED:0.06 eAED:0.16 QI:0|-1|0|1|-1|1|1|0|613</Iteration_query-def>
  <Iteration_query-len>1842</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1186987773</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058589-RA transcript Note:&quot;Similar to TLR1 Toll-like receptor 1 (Homo sapiens)&quot; offset:0 AED:0.23 eAED:0.23 QI:0|0|0|1|0|0|2|0|543</Iteration_query-def>
  <Iteration_query-len>1632</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>1032150150</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0010990-RA transcript Note:&quot;Similar to Uba1 Ubiquitin-like modifier-activating enzyme 1 (Rattus norvegicus)&quot; offset:65 AED:1.00 eAED:1.00 QI:65|0|0|0|0.45|0.41|12|0|456</Iteration_query-def>
  <Iteration_query-len>1436</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YKL210W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:39163:42237:1 gene:YKL210W transcript:YKL210W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBA1 description:Ubiquitin activating enzyme (E1); involved in ubiquitin-mediated protein degradation and essential for viability; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001693]</Hit_def>
  <Hit_accession>YKL210W</Hit_accession>
  <Hit_len>1024</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>272.322</Hsp_bit-score>
      <Hsp_score>695</Hsp_score>
      <Hsp_evalue>4.10267e-82</Hsp_evalue>
      <Hsp_query-from>84</Hsp_query-from>
      <Hsp_query-to>1400</Hsp_query-to>
      <Hsp_hit-from>13</Hsp_hit-from>
      <Hsp_hit-to>625</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>203</Hsp_identity>
      <Hsp_positive>289</Hsp_positive>
      <Hsp_gaps>176</Hsp_gaps>
      <Hsp_align-len>614</Hsp_align-len>
      <Hsp_qseq>DIDEEYFSRQLYVLGHEATRRIQEAHVLVSGMHGLGLEVAKNXXXXXXXXXXXHDTQPLARRDLSSQFYGREEDLKRNRAQLSQSHL------------------KQLNEF--------------VRVSDYSDSLTEEFLSQFQESL---------------------------------GVVTCAEAEGHDFENGDLVVFSGVRGMTELNRCR----------------------------------PRTVT---VIEALVRPRF--QEGCDQTVALTLHKAFQALHRFQQKQN-RSPRPHNQADADEVVK---------------------------------ESAXXXXXXXXXXXXXXXXACTGSFMPLNQWMYYSAAKCLPDECAGTVDMEEACKPTDSRYDGQIAVFGKKFQEKLASLKYFLVGAGAIGCELLKNFAMMGLGE-----VTVTDMDNIERSNLHRQFLFRPGDVKKPKSEVAARAASEMNPDV--RITPHRLSVGPASESVFGKSFFDELD-----------------GCVNHRKPLLESGTEGLEGSVHVVVPFLTQSYGCVANPRKKTIPLCS-------------WAKEEFEELFA</Hsp_qseq>
      <Hsp_hseq>EIDESLYSRQLYVLGKEAMLKMQTSNVLILGLKGLGVEIAKNVVLAGVKSMTVFDPEPVQLADLSTQFFLTEKDIGQKRGDVTRAKLAELNAYVPVNVLDSLDDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVLDPTGEEPRTGMVSDIEPDGTVTMLDDNRHGLEDGNFVRFSEVEGLDKLNDGTLFKVEVLGPFAFRIGSVKEYGEYKKGGIFTEVKVPRKISFKSLKQQLSNPEFVFSDFAKFDRAAQLHLGFQALHQFAVRHNGELPRTMNDEDANELIKLVTDLSVQQPEVLGEGVDVNEDLIKELSYQARGDIPGVVAFFGGLVAQEVLKACSGKFTPLKQFMYFDSLESLPDPKNFPRN-EKTTQPVNSRYDNQIAVFGLDFQKKIANSKVFLVGSGAIGCEMLKNWALLGLGSGSDGYIVVTDNDSIEKSNLNRQFLFRPKDVGKNKSEVAAEAVCAMNPDLKGKINAKIDKVGPETEEIFNDSFWESLDFVTNALDNVDARTYVDRRCVFYRKPLLESGTLGTKGNTQVIIPRLTESYSSSRDPPEKSIPLCTLRSFPNKIDHTIAWAKSLFQGYFT</Hsp_hseq>
      <Hsp_midline>+IDE  +SRQLYVLG EA  ++Q ++VL+ G+ GLG+E+AKNVVL GV ++TV D +P+   DLS+QF+  E+D+ + R  ++++ L                   QL++F              V+++++  S    F+S     L                                 G VT  +   H  E+G+ V FS V G+ +LN                                     PR ++   + + L  P F   +      A  LH  FQALH+F  + N   PR  N  DA+E++K                                 +   V       V  +   AC+G F PL Q+MY+ + + LPD      + E+  +P +SRYD QIAVFG  FQ+K+A+ K FLVG+GAIGCE+LKN+A++GLG      + VTD D+IE+SNL+RQFLFRP DV K KSEVAA A   MNPD+  +I      VGP +E +F  SF++ LD                  CV +RKPLLESGT G +G+  V++P LT+SY    +P +K+IPLC+             WAK  F+  F </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YDR390C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1254937:1256847:-1 gene:YDR390C transcript:YDR390C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBA2 description:Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Aos1p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability [Source:SGD;Acc:S000002798]</Hit_def>
  <Hit_accession>YDR390C</Hit_accession>
  <Hit_len>636</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>112.464</Hsp_bit-score>
      <Hsp_score>280</Hsp_score>
      <Hsp_evalue>5.45217e-27</Hsp_evalue>
      <Hsp_query-from>882</Hsp_query-from>
      <Hsp_query-to>1400</Hsp_query-to>
      <Hsp_hit-from>3</Hsp_hit-from>
      <Hsp_hit-to>203</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>204</Hsp_align-len>
      <Hsp_qseq>RYDGQIAVFGKKFQEKLASLKYFLVGAGAIGCELLKNFAMMGLGEVTVTDMDNIERSNLHRQFLFRPGDVKKPKSEVAARAASEMNPDVRITPHRLSVGPASESVFGKSFFDELDGCVNHRK-----------------PLLESGTEGLEGSVHVVVPFLTQSYGCVANPRKKTIPLCS-------------WAKE-EFEELFA</Hsp_qseq>
      <Hsp_hseq>RETSLVTIIGEDSYKKLRSSRCLLVGAGGIGSELLKDIILMEFGEIHIVDLDTIDLSNLNRQFLFRQKDIKQPKSTTAVKAVQHFN-NSKLVPYQGNV--MDISTFPLHWFEQFDIIFNALDNLAARRYVNKISQFLSLPLIESGTAGFDGYMQPIIPGKTECFECTKKETPKTFPVCTIRSTPSQPIHCIVWAKNFLFNQLFA</Hsp_hseq>
      <Hsp_midline>R    + + G+   +KL S +  LVGAG IG ELLK+  +M  GE+ + D+D I+ SNL+RQFLFR  D+K+PKS  A +A    N + ++ P++ +V     S F   +F++ D   N                    PL+ESGT G +G +  ++P  T+ + C      KT P+C+             WAK   F +LFA</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YPR066W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:681213:682112:1 gene:YPR066W transcript:YPR066W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBA3 description:Protein that activates Rub1p (NEDD8) before neddylation; acts together with Ula1p; may play a role in protein degradation; GFP-fusion protein localizes to the cytoplasm in a punctate pattern [Source:SGD;Acc:S000006270]</Hit_def>
  <Hit_accession>YPR066W</Hit_accession>
  <Hit_len>299</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>91.6633</Hsp_bit-score>
      <Hsp_score>226</Hsp_score>
      <Hsp_evalue>4.20865e-21</Hsp_evalue>
      <Hsp_query-from>942</Hsp_query-from>
      <Hsp_query-to>1376</Hsp_query-to>
      <Hsp_hit-from>4</Hsp_hit-from>
      <Hsp_hit-to>172</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>169</Hsp_align-len>
      <Hsp_qseq>KYFLVGAGAIGCELLKNFAMMG-LGEVTVTDMDNIERSNLHRQFLFRPGDVKKPKSEVAARAASEMNPDVRITPH--RLSVGPAS------------ESVFGKSFFDE------LDGCVNHRKPLLESGTEGLEGSVHVVVPFLTQSYGCVAN---PRKKTIPLCSWAK</Hsp_qseq>
      <Hsp_hseq>KILVLGAGGLGCEILKNLTMLSFVKQVHIVDIDTIELTNLNRQFLFCDKDIGKPKAQVAAQYVNTRFPQLEVVAHVQDLTTLPPSFYKDFQFIISGLDAIEPRRFINETLVKLTLESNYEICIPFIDGGTEGLKGHVKTIIPGITACWECSIDTLPSQQDTVPMCTIAN</Hsp_hseq>
      <Hsp_midline>K  ++GAG +GCE+LKN  M+  + +V + D+D IE +NL+RQFLF   D+ KPK++VAA+  +   P + +  H   L+  P S            +++  + F +E      L+       P ++ GTEGL+G V  ++P +T  + C  +    ++ T+P+C+ A </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YHR111W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:333072:334394:1 gene:YHR111W transcript:YHR111W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBA4 description:E1-like protein that activates Urm1p before urmylation; also acts in thiolation of the wobble base of cytoplasmic tRNAs by adenylating and then thiolating Urm1p; receives sulfur from Tum1p [Source:SGD;Acc:S000001153]</Hit_def>
  <Hit_accession>YHR111W</Hit_accession>
  <Hit_len>440</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>3.14997e-11</Hsp_evalue>
      <Hsp_query-from>882</Hsp_query-from>
      <Hsp_query-to>1214</Hsp_query-to>
      <Hsp_hit-from>46</Hsp_hit-from>
      <Hsp_hit-to>161</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>116</Hsp_align-len>
      <Hsp_qseq>RYDGQIAV---FGKKFQEKLASLKYFLVGAGAIGCELLKNFAMMGLGEVTVTDMDNIERSNLHRQFLFRPGDVKKPKSEVAARAASEMNPDVRIT--PHRLSVGPASESVFGKSFF</Hsp_qseq>
      <Hsp_hseq>RYGRQMIVEETGGVAGQVKLKNTKVLVVGAGGLGCPALPYLAGAGVGQIGIVDNDVVETSNLHRQVLHDSSRVGMLKCESARQYITKLNPHINVVTYPVRLNSSNAFDIFKGYNYI</Hsp_hseq>
      <Hsp_midline>RY  Q+ V    G   Q KL + K  +VGAG +GC  L   A  G+G++ + D D +E SNLHRQ L     V   K E A +  +++NP + +   P RL+   A +   G ++ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YPR180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:895961:897004:1 gene:YPR180W transcript:YPR180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AOS1 description:Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006384]</Hit_def>
  <Hit_accession>YPR180W</Hit_accession>
  <Hit_len>347</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>2.27386e-09</Hsp_evalue>
      <Hsp_query-from>885</Hsp_query-from>
      <Hsp_query-to>1316</Hsp_query-to>
      <Hsp_hit-from>16</Hsp_hit-from>
      <Hsp_hit-to>172</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>159</Hsp_align-len>
      <Hsp_qseq>YDGQIAVFGKKFQEKLASLKYFLVGAGAIGCELLKNFAMMGLGEVTVTDMDNIERSNLHRQFLFRPGDVKKPKSEVAARAASEMNPDVRITPHRLSVGPASESVFGKSFFD-------ELDGCVN----HRK---PLLESGTEGLEGSVHV-VVPFLTQ</Hsp_qseq>
      <Hsp_hseq>YDRQIRLWGMTAQANMRSAKVLLINLGAIGSEITKSIVLSGIGHLTILDGHMVTEEDLGSQFFIGSEDVGQWKIDATKERIQDLNPRIELNFDKQDLQEKDEEFFQQ--FDLVVATEMQIDEAIKINTLTRKLNIPLYVAGSNGLFAYVFIDLIEFISE</Hsp_hseq>
      <Hsp_midline>YD QI ++G   Q  + S K  L+  GAIG E+ K+  + G+G +T+ D   +   +L  QF     DV + K +       ++NP + +   +  +    E  F +  FD       ++D  +      RK   PL  +G+ GL   V + ++ F+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YHR171W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:445713:447605:1 gene:YHR171W transcript:YHR171W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG7 description:Autophagy-related protein and dual specificity member of the E1 family; mediates the attachment of Atg12p to Atg5p and Atg8p to phosphatidylethanolamine which are required steps in autophagosome formation; E1 enzymes are also known as ubiquitin-activating enzymes; involved in methionine restriction extension of chronological lifespan in an autophagy-dependent manner [Source:SGD;Acc:S000001214]</Hit_def>
  <Hit_accession>YHR171W</Hit_accession>
  <Hit_len>630</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>1.83035e-06</Hsp_evalue>
      <Hsp_query-from>942</Hsp_query-from>
      <Hsp_query-to>1175</Hsp_query-to>
      <Hsp_hit-from>326</Hsp_hit-from>
      <Hsp_hit-to>403</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>26</Hsp_identity>
      <Hsp_positive>42</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>78</Hsp_align-len>
      <Hsp_qseq>KYFLVGAGAIGCELLKNFAMMGLGEVTVTDMDNIERSNLHRQFLFRPGDVKKPKSEVAARAASEMNPDVRITPHRLSV</Hsp_qseq>
      <Hsp_hseq>KVLLLGAGTLGCYVSRALIAWGVRKITFVDNGTVSYSNPVRQALYNFEDCGKPKAELAAASLKRIFPLMDATGVKLSI</Hsp_hseq>
      <Hsp_midline>K  L+GAG +GC + +     G+ ++T  D   +  SN  RQ L+   D  KPK+E+AA +   + P +  T  +LS+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>93</Statistics_hsp-len>
      <Statistics_eff-space>885602795</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058603-RA transcript Note:&quot;Similar to TBK1 Serine/threonine-protein kinase TBK1 (Homo sapiens)&quot; offset:0 AED:0.38 eAED:0.38 QI:0|0|0|0.30|1|1|13|0|456</Iteration_query-def>
  <Iteration_query-len>1371</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>99.3673</Hsp_bit-score>
      <Hsp_score>246</Hsp_score>
      <Hsp_evalue>1.31938e-22</Hsp_evalue>
      <Hsp_query-from>31</Hsp_query-from>
      <Hsp_query-to>624</Hsp_query-to>
      <Hsp_hit-from>200</Hsp_hit-from>
      <Hsp_hit-to>409</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>218</Hsp_align-len>
      <Hsp_qseq>LTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQERESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYG-LSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGEQFVSLCGT------------------EEYLPR-AYHATVDLWSIGVTIYHVATGCLPWA</Hsp_qseq>
      <Hsp_hseq>IDEVVGQGAFATVKKAIERTTGKTFAVKIISKRKVIGNMDGVTRELEVLQKLNHPRIVRLKGFYED--TESYYMVMEFVSGGDLMDFVA----AHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNIL--IEQDDPVLVKITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFS</Hsp_hseq>
      <Hsp_midline>+ +V+G+G+   V     RTTG   A+K++S   +    +   RE  VL +L+HP IVRL    E+  T    +VME  SGG L   +     A+G + ED   ++   ++  + ++   GI HRDLKP NI+     D     K+TDF  A+   +G    + CGT                  +EY  R  Y + VD+WS+G  +Y + TG LP++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>92.4337</Hsp_bit-score>
      <Hsp_score>228</Hsp_score>
      <Hsp_evalue>2.47361e-20</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>19</Hsp_hit-from>
      <Hsp_hit-to>231</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>223</Hsp_align-len>
      <Hsp_qseq>WSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVL-------------SVDGMRRPPELQ---ERESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGEQFVSLCGTEEY--------LPRAYHATVDLWSIGVTIYHVATGCLPW</Hsp_qseq>
      <Hsp_hseq>WKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLY--LVLEYAEKGELFNLLVE---RGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLL----LDHKYNIKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQGFAS-DVWSCGVILFALLTGRLPF</Hsp_hseq>
      <Hsp_midline>W L + LG GSTG V   R+ +TG  +A+KV+             S+ G   P  L    ERE  ++  L+HPN++RL  V E +   +  +V+E    G L ++L E      L E + ++    ++ G+++    GIVHRDLKP N++     D K   K+ DF  A    +G+   + CG+  Y        +P    A+ D+WS GV ++ + TG LP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>89.7373</Hsp_bit-score>
      <Hsp_score>221</Hsp_score>
      <Hsp_evalue>1.21045e-19</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>329</Hsp_hit-from>
      <Hsp_hit-to>542</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>217</Hsp_align-len>
      <Hsp_qseq>VLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQE--RESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIM-------------RAFRADG--KATYKLTDFDTARWLEDGEQFVSLCGTEEYLP------RAYHATVDLWSIGVTIYHVATGCLPW</Hsp_qseq>
      <Hsp_hseq>LLGQGDVGKVYLVRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPFIVTLYHSFQ--TKDYLYLCMEYCMGGEFFRAL-QTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPF</Hsp_hseq>
      <Hsp_midline>+LG+G  G VY  R R T    A+KVL+   M +  +++    E  +LA  DHP IV L    +     +  + ME C GG     L +   +  ++E+D     S+VVA + +L   G ++RDLKP NI+              + +A G  K T K + +   +   DG +  S  GTEEYL         + A VD W++G+ IY +  GC P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.5817</Hsp_bit-score>
      <Hsp_score>218</Hsp_score>
      <Hsp_evalue>4.29805e-19</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>630</Hsp_query-to>
      <Hsp_hit-from>1034</Hsp_hit-from>
      <Hsp_hit-to>1255</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>234</Hsp_align-len>
      <Hsp_qseq>WSLTDVLGRGSTGCVYHGRHRTTG---APSAIKVLSVDGMRRPPELQERESRVLAELDHPNIVRLLAVEEESVTRHRV-VVMEVCSGGSLHSILNEPENAYGLSEDDFL-QVLS-DVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWL-----------------EDGEQFVSLCGTEEYL-PRAYHATV--------DLWSIGVTIYHVATGCLPWAQL</Hsp_qseq>
      <Hsp_hseq>WQKRSFIGGGTFGQVYSAINLENGEILAVKEIKIHDTTTMKKIFPLIKEEMTVLEMLNHPNIVQYYGVE---VHRDKVNIFMEYCEGGSLASLLD-----HGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDF----NGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPWSNL</Hsp_hseq>
      <Hsp_midline>W     +G G+ G VY   +   G   A   IK+     M++   L + E  VL  L+HPNIV+   VE   V R +V + ME C GGSL S+L+     +G  ED+ + QV + +++ G+ +L + G+VHRD+KP NI+  F        K  DF TAR +                  + +    + GT  Y+ P     +         D+W++G  +  +ATG  PW+ L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.4261</Hsp_bit-score>
      <Hsp_score>215</Hsp_score>
      <Hsp_evalue>5.01248e-19</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>627</Hsp_query-to>
      <Hsp_hit-from>18</Hsp_hit-from>
      <Hsp_hit-to>219</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>209</Hsp_align-len>
      <Hsp_qseq>WSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQERESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGEQFVSLCGTEEYL-PRA-------YHATVDLWSIGVTIYHVATGCLPWAQ</Hsp_qseq>
      <Hsp_hseq>YSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMW--IVMEYCGGGSCSDLLKR-SYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANIL----LNEEGMVKLGDFGVSGHIRSTLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPPLSK</Hsp_hseq>
      <Hsp_midline>+S+   +GRG+ G VY    R T    AIKV++++      EL  +E   LAEL  P I   +A   E V+    +VME C GGS   +L       GL E+    ++ +V  G+ +L E+  +HRD+K  NI+     + +   KL DF  +  +    +  +  GT  ++ P         Y+   D+WS+G+T Y +  G  P ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.2705</Hsp_bit-score>
      <Hsp_score>212</Hsp_score>
      <Hsp_evalue>7.02577e-19</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>690</Hsp_query-to>
      <Hsp_hit-from>82</Hsp_hit-from>
      <Hsp_hit-to>307</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>237</Hsp_align-len>
      <Hsp_qseq>WSLTDV-----LGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQ--ERESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGEQFVSLCGTEEYLP------RAYHATVDLWSIGVTIYHVATGCLPWAQLQELLSGLTGVTPDLQL--FFNE</Hsp_qseq>
      <Hsp_hseq>YSLQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDA--QQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYA---AEVCLALEYLHSKDIIYRDLKPENIL----LDKNGHIKITDFGFAKYVPDVT--YTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNE</Hsp_hseq>
      <Hsp_midline>+SL D      LG GS G V+  R R  G   A+KVL  + + R  +++    E  +L+ + HP I+R+    +++  +   ++M+   GG L S+L + +         +    ++V   + +L  K I++RDLKP NI+     D     K+TDF  A+++ D     +LCGT +Y+       + Y+ ++D WS G+ IY +  G  P+     + +    +  +L+   FFNE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.8853</Hsp_bit-score>
      <Hsp_score>211</Hsp_score>
      <Hsp_evalue>1.00431e-18</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>83</Hsp_hit-from>
      <Hsp_hit-to>283</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>212</Hsp_align-len>
      <Hsp_qseq>WSLTDV-----LGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQ--ERESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGEQFVSLCGTEEYLP------RAYHATVDLWSIGVTIYHVATGCLPW</Hsp_qseq>
      <Hsp_hseq>YSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDS--QQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYA---AEVCLALEYLHSKDIIYRDLKPENIL----LDKNGHIKITDFGFAKYVPDVT--YTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPF</Hsp_hseq>
      <Hsp_midline>+SL+D      LG GS G V+  R    G   A+K L    + +  +++    E R+L+ + HP I+R+    ++S  +   +VM+   GG L S+L + +         +    ++V   + +L  K I++RDLKP NI+     D     K+TDF  A+++ D     +LCGT +Y+       + Y+ +VD WS GV IY +  G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.6557</Hsp_bit-score>
      <Hsp_score>213</Hsp_score>
      <Hsp_evalue>1.93492e-18</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>639</Hsp_query-to>
      <Hsp_hit-from>23</Hsp_hit-from>
      <Hsp_hit-to>226</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>217</Hsp_align-len>
      <Hsp_qseq>WSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQERESRVLAELDH-PNIVRLLA--VEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQV-LSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGE-QFVSLCGTEEYL-PRA------YHATVDLWSIGVTIYHVATGCLPWAQLQEL</Hsp_qseq>
      <Hsp_hseq>FKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSL----WIIMEHCAGGSLRSLLRP-----GKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVL----ITNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYCDVEAL</Hsp_hseq>
      <Hsp_midline>+  T+V+GRG  G VY G +  TG   AIKVL++D      E  +RE + LA L    NI R     +++ S+     ++ME C+GGSL S+L       G  ++ ++ V + +++  +  + +  ++HRD+K  N++       +   KL DF  A  +     +  ++ GT  ++ P        Y   VD+WS+G+T Y +ATG  P+  ++ L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.2705</Hsp_bit-score>
      <Hsp_score>212</Hsp_score>
      <Hsp_evalue>2.55346e-18</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>627</Hsp_query-to>
      <Hsp_hit-from>21</Hsp_hit-from>
      <Hsp_hit-to>229</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>220</Hsp_align-len>
      <Hsp_qseq>WSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRP----------PELQERESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYG-LSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGEQFVSLCGTEEY--------LPRAYHATVDLWSIGVTIYHVATGCLPWAQ</Hsp_qseq>
      <Hsp_hseq>WKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWE--TNNNLYLILEYAEKGELFNLLVD----HGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLL----LDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFAS-DVWSCGVILFALLTGRLPFDE</Hsp_hseq>
      <Hsp_midline>W L + LG GSTG V   +H  TG  +A+KV+S                 P   ERE  ++  L HPN++ L  V E     +  +++E    G L ++L +    +G L E + +     ++ G+++    GIVHRDLKP N++     D     K+ DF  A    D +   + CG+  Y        LP    A+ D+WS GV ++ + TG LP+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.5001</Hsp_bit-score>
      <Hsp_score>210</Hsp_score>
      <Hsp_evalue>4.34705e-18</Hsp_evalue>
      <Hsp_query-from>13</Hsp_query-from>
      <Hsp_query-to>633</Hsp_query-to>
      <Hsp_hit-from>1171</Hsp_hit-from>
      <Hsp_hit-to>1384</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>ENFTWSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSV-------DGMRRPPELQERESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLS-DVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLED--GEQFVSLCGTEEYLP-------RAYHATVDLWSIGVTIYHVATGCLPWAQLQ</Hsp_qseq>
      <Hsp_hseq>KEFAWMKGEMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNNIYS--LFLEYVAGGSVGSLIR----MYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLL----LDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLE</Hsp_hseq>
      <Hsp_midline>+ F W   +++G+GS G VY   + TTG   A+K + V       + +    E    E   L +LDH NIV+ L  E ++      + +E  +GGS+ S++      YG  ++  ++ L+  V+ G+ +L  KGI+HRD+K  N++     D     K++DF  +R  +D      +++ GT  ++        + Y A VD+WS+G  +  +  G  PW+ L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.1889</Hsp_bit-score>
      <Hsp_score>204</Hsp_score>
      <Hsp_evalue>6.46101e-18</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>70</Hsp_hit-from>
      <Hsp_hit-to>265</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>207</Hsp_align-len>
      <Hsp_qseq>WSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQER--ESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGEQFVSLCGTEEYLP------RAYHATVDLWSIGVTIYHVATGCLPW</Hsp_qseq>
      <Hsp_hseq>FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDA--RNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYA---AEVILALEYLHAHNIIYRDLKPENIL----LDRNGHIKITDFGFAKEVQTVTW--TLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPF</Hsp_hseq>
      <Hsp_midline>+ +   LG GS G V+  R    G   AIKVL    + +  +++    E R+L  ++HP ++R+    +++  R+  +VM+   GG L S+L + +         +    ++V+  + +L    I++RDLKP NI+     D     K+TDF  A+ ++      +LCGT +Y+       + Y+ +VD WS+GV IY +  G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.1889</Hsp_bit-score>
      <Hsp_score>204</Hsp_score>
      <Hsp_evalue>1.27495e-17</Hsp_evalue>
      <Hsp_query-from>43</Hsp_query-from>
      <Hsp_query-to>624</Hsp_query-to>
      <Hsp_hit-from>206</Hsp_hit-from>
      <Hsp_hit-to>422</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>221</Hsp_align-len>
      <Hsp_qseq>LGRGSTGCVYHGRHRTTGAPSAIKVLSV---DGMRRPPELQERESRVLAELDHPNIVRLLAVEEESVTRHRV---VVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAF-RADGKA--------------TYKLTDFDTARWLEDGEQFVSLCGTEEYL------PRAYHATVDLWSIGVTIYHVATGCLPWA</Hsp_qseq>
      <Hsp_hseq>LGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFRE-ETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERI---VRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVILYVCLCGFPPFS</Hsp_hseq>
      <Hsp_midline>LG G    V   +++ TG   A+K+      D  ++  + +E E+ +L  + HPNIV LL    E +++ ++   +V+E    G L   +        L +D+   +   ++ G+ +L E+ I+HRD+KP NI+    R +  +                K+ DF  A++  + +   +LCGT  Y+       + Y + VDLWS GV +Y    G  P++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.1889</Hsp_bit-score>
      <Hsp_score>204</Hsp_score>
      <Hsp_evalue>1.64366e-17</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>45</Hsp_hit-from>
      <Hsp_hit-to>276</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>244</Hsp_align-len>
      <Hsp_qseq>QLSENFTWSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQ--------ERESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPEN-----AYGLSEDDFLQ---VLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDG--------EQFVS-------------LCGTE-EYLPRAYHATVDLWSIGVTIYHVATGCLPW</Hsp_qseq>
      <Hsp_hseq>QILNNF--EILATLGNGQYGKVKLARDLGTGALVAIKILNRFEKRSGYSLQLKVENPRVNQEIEVMKRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVKWC---PENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLL----ISSNGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEY---SCSSAIDIWSLGVTIYCLLFGKLPF</Hsp_hseq>
      <Hsp_midline>Q+  NF   +   LG G  G V   R   TGA  AIK+L+    R    LQ         +E  V+    H N+V L  +  +  +    +V+E CS G +      PEN     A G S   F Q   V+ DVV+G+ +L  +GI HRD+KP N++         T K++DF  A     G        EQ +              LC TE EY   +  + +D+WS+GVTIY +  G LP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.1889</Hsp_bit-score>
      <Hsp_score>204</Hsp_score>
      <Hsp_evalue>1.96553e-17</Hsp_evalue>
      <Hsp_query-from>43</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>30</Hsp_hit-from>
      <Hsp_hit-to>267</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>51</Hsp_gaps>
      <Hsp_align-len>241</Hsp_align-len>
      <Hsp_qseq>LGRGSTGCVYHGRHRTTGAPS--AIKVLSVDGMRRPPELQ--ERESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSIL--------NEP-------------ENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIM-----------RAFRADGKA------TYKLTDFDTARWLEDGEQFVSLCGTEEYLP------RAYHATVDLWSIGVTIYHVATGCLPW</Hsp_qseq>
      <Hsp_hseq>IGKGSFATVYRG-HLTSDKSQHVAIKEVSRAKLKNKKLLENLEIEIAILKKIKHPHIVGLIDCERTSTDFY--LIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVVFEMCCGTPPF</Hsp_hseq>
      <Hsp_midline>+G+GS   VY G H T+      AIK +S   ++    L+  E E  +L ++ HP+IV L+  E  S   +  ++ME C+ G L  +L        N P             EN  GL     L  L  + + +  LR K +VHRD+KP N++           ++F   G          K+ DF  AR+L +     +LCG+  Y+       + Y+A  DLWS+G  ++ +  G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.0333</Hsp_bit-score>
      <Hsp_score>201</Hsp_score>
      <Hsp_evalue>4.82488e-17</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>648</Hsp_query-to>
      <Hsp_hit-from>46</Hsp_hit-from>
      <Hsp_hit-to>261</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>225</Hsp_align-len>
      <Hsp_qseq>WSLTDVLGRGSTGCVYHGRHRTTGAPS-----AIKVLSVDGMRRPPELQ---ERESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFD-TARWLEDGEQFVSLCGTEEYLP-------RAYHA-TVDLWSIGVTIYHVATGCLPWAQLQELLSG</Hsp_qseq>
      <Hsp_hseq>YIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEVLQNS--KYIGIVLEFVSGGEFYKYI---QRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLL----LDKHENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPTG</Hsp_hseq>
      <Hsp_midline>+ +   LG G  G V  G  + + +       AIK++  D +++  + +    RE   L  L HPNI+ L  V + S  ++  +V+E  SGG  +  +   +    L E    ++ + +++G+N++  KG+VHRDLK  N++     D      +TDF     + ED E   + CG+  Y         +AY A   D+WS GV +Y +  G LPW    E  +G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.0333</Hsp_bit-score>
      <Hsp_score>201</Hsp_score>
      <Hsp_evalue>5.51252e-17</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>630</Hsp_query-to>
      <Hsp_hit-from>1266</Hsp_hit-from>
      <Hsp_hit-to>1503</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>60</Hsp_gaps>
      <Hsp_align-len>250</Hsp_align-len>
      <Hsp_qseq>WSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSVD---GMRRPPELQERESRVLAELDHPNIVRLLAVEEESVTRHRV-VVMEVCSGGSLHSILNEPENAYGLSEDDFL-QVLS-DVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWL---------------EDGEQ------------------FVSLCGTEEYL-PRAYHATV--------DLWSIGVTIYHVATGCLPWAQL</Hsp_qseq>
      <Hsp_hseq>WQKRNFIGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGVE---VHRDKVNIFMEYCEGGSLAALLE-----HGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDF----NGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPWANL</Hsp_hseq>
      <Hsp_midline>W   + +G G+ G VY       G   A+K +++     M++   L + E  VL  L+HPNIV    VE   V R +V + ME C GGSL ++L      +G  ED+ + QV +  ++ G+ +L E GIVHRD+KP NI+  F        K  DF  A+ +                DGE                    + + GT  Y+ P +   +         D+WS+G  +  + TG  PWA L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.4925</Hsp_bit-score>
      <Hsp_score>197</Hsp_score>
      <Hsp_evalue>1.60757e-16</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>636</Hsp_query-to>
      <Hsp_hit-from>25</Hsp_hit-from>
      <Hsp_hit-to>223</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>210</Hsp_align-len>
      <Hsp_qseq>WSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQERESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGEQFVSLCGTEEYLP------RAYHATVDLWSIGVTIYHVATGCLPWAQLQE</Hsp_qseq>
      <Hsp_hseq>YHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMA-EISLLKNLNHNNIVKYHGFIRKSYELY--ILLEYCANGSLRRLISR--SSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLS--ADN--TVKLADFGVSTIVNSSA--LTLAGTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNPPYHNLTD</Hsp_hseq>
      <Hsp_midline>+ L  V+GRGS G VY   ++ T    AIK +  +      ++   E  +L  L+H NIV+      +S   +  +++E C+ GSL  +++   ++ GLSE++    ++  + G+ +L  +G++HRD+K  NI+ +  AD   T KL DF  +  +      ++L GT  ++       R      D+WS+G T+  + T   P+  L +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.5666</Hsp_bit-score>
      <Hsp_score>192</Hsp_score>
      <Hsp_evalue>4.27085e-16</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>155</Hsp_hit-from>
      <Hsp_hit-to>385</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>233</Hsp_align-len>
      <Hsp_qseq>LSENFTWSLTD-VLGRGSTGCV---YHGRHRTTGAPSAIKVLSVDGMRRPPELQERESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLE-DGEQFVSLCGTEEYLP-----------------------RAYHATVDLWSIGVTIYHVATGCLPW</Hsp_qseq>
      <Hsp_hseq>LREVDQWEITNRIVGNGTFGHVLITHNSKERDEDVCYHPENYAVKIIKLKPNKFDKEARILLRLDHPNIIKVYHTFCDR-NNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLC-TPEPCTRIVLADFGIAKDLNSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGISPF</Hsp_hseq>
      <Hsp_midline>L E   W +T+ ++G G+ G V   ++ + R        +  +V  ++  P   ++E+R+L  LDHPNI+++     +    H  +  ++  GG L S L + +    +SE + L ++  ++  +N+L ++ IVHRDLK  NI+     +      L DF  A+ L  + E+  ++ GT EY                         R Y +  DLWS+GV  + + TG  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.0258</Hsp_bit-score>
      <Hsp_score>188</Hsp_score>
      <Hsp_evalue>1.86829e-15</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>501</Hsp_hit-from>
      <Hsp_hit-to>717</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>225</Hsp_align-len>
      <Hsp_qseq>VLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQE--RESRVLAELDHPNIVRLL-AVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTA----------------------RWLEDGEQFVSLCGTEEYLP------RAYHATVDLWSIGVTIYHVATGCLPW</Hsp_qseq>
      <Hsp_hseq>LLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQEILATSNHPFIVTLYHSFQSED---YLYLCMEYCMGGEFFRAL-QTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENIL--LHQSGHIM--LSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPF</Hsp_hseq>
      <Hsp_midline>+LG+G  G V+  R + T    A+KVLS D M +  +++    E  +LA  +HP IV L  + + E    +  + ME C GG     L +      + EDD     S+V A + +L   G ++RDLKP NI+      G     L+DFD +                      +   DG +  S  GTEEY+         + A VD W++G+ IY +  G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.0998</Hsp_bit-score>
      <Hsp_score>183</Hsp_score>
      <Hsp_evalue>2.84062e-15</Hsp_evalue>
      <Hsp_query-from>67</Hsp_query-from>
      <Hsp_query-to>627</Hsp_query-to>
      <Hsp_hit-from>118</Hsp_hit-from>
      <Hsp_hit-to>303</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>200</Hsp_align-len>
      <Hsp_qseq>VYHGRHRTTGAPSAIKVLSVDGMRRPPELQE---RESRVLAELDHPNIVRLLAV--EEESVTRHRVVVMEVCSGGSLHSIL--NEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGEQFVSLCGTEEYL------PRAYHATVDLWSIGVTIYHVATGCLPWAQ</Hsp_qseq>
      <Hsp_hseq>VYCVRHRSTGYICALKVMEKEEIIKY-NLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRV----YLLMEYLVNGEMYKLLRLHGPFNDI-LASDYIYQIAN----ALDYMHKKNIIHRDIKPENILIGF----NNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPPFEE</Hsp_hseq>
      <Hsp_midline>VY  RHR+TG   A+KV+  + + +   LQ+   RE  +   L+HPN+ +      +E+ V     ++ME    G ++ +L  + P N   L+ D   Q+ +     ++++ +K I+HRD+KP NI+  F        KLTDF  +       +  ++CGT +YL       R Y  T+D W++GV  + + TG  P+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.0998</Hsp_bit-score>
      <Hsp_score>183</Hsp_score>
      <Hsp_evalue>4.54315e-15</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>675</Hsp_query-to>
      <Hsp_hit-from>226</Hsp_hit-from>
      <Hsp_hit-to>448</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>234</Hsp_align-len>
      <Hsp_qseq>VLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQE---RESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSIL-NEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGEQFVSLC----GTEEYLP------RAYHATVDLWSIGVTIYHVATGCLPWAQLQ--------ELLSGLTGVTPDLQ</Hsp_qseq>
      <Hsp_hseq>ILGEGAGGSVSKCKLKNGSKIFALKV--INTLNTDPEYQKQIFRELQFNRSFQSEYIVRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNIL--LNENGQV--KLCDFGVS-----GEAVNSLATTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANGKFPCSSEKMAANIAPFELLMWILTFTPELK</Hsp_hseq>
      <Hsp_midline>+LG G+ G V   + +      A+KV  ++ +   PE Q+   RE +         IVR   +  +       + ME   G SL +I  N  E    +SE    ++   V+ G+++L EK ++HRD+KP NI+     +G+   KL DF  +     GE   SL     GT  Y+       + Y  T D+WS+G+TI  VA G  P +  +        ELL  +   TP+L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.9442</Hsp_bit-score>
      <Hsp_score>180</Hsp_score>
      <Hsp_evalue>1.66263e-14</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>344</Hsp_hit-from>
      <Hsp_hit-to>542</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>208</Hsp_align-len>
      <Hsp_qseq>WSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQER--ESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARW-LEDGEQFVSLCGTEEYLP------RAYHATVDLWSIGVTIYHVATGCLPW</Hsp_qseq>
      <Hsp_hseq>FDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLY--LVLAFINGGELFYHLQH-EGRFSLARSRF--YIAELLCALDSLHKLDVIYRDLKPENIL----LDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPY</Hsp_hseq>
      <Hsp_midline>+ L  V+G+GS G V   R + T    A+K L    +    E+     E  VLA +D P IV L    +     +  +V+   +GG L   L   E  + L+   F   +++++  ++ L +  +++RDLKP NI+     D +    L DF   +  ++D ++  + CGT EYL       + Y  TVD W++G+ +Y + TG  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.559</Hsp_bit-score>
      <Hsp_score>179</Hsp_score>
      <Hsp_evalue>1.85998e-14</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>54</Hsp_hit-from>
      <Hsp_hit-to>252</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>210</Hsp_align-len>
      <Hsp_qseq>TWSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQ---ERESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGEQFVSLCGTEEY-LPRAYHAT------VDLWSIGVTIYHVATGCLPW</Hsp_qseq>
      <Hsp_hseq>NYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKS-DMQGRIEREISYLRLLRHPHIIKLYDVIK---SKDEIIMVIEYAGNELFDYIVQRDK---MSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLL----LDEHLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPF</Hsp_hseq>
      <Hsp_midline> + +   LG GS G V    H TTG   A+K+++   + +  ++Q   ERE   L  L HP+I++L  V +   ++  ++++   +G  L   + + +    +SE +  +    +++ + +     IVHRDLKP N++     D     K+ DF  +  + DG    + CG+  Y  P            VD+WS GV +Y +    LP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.559</Hsp_bit-score>
      <Hsp_score>179</Hsp_score>
      <Hsp_evalue>2.72402e-14</Hsp_evalue>
      <Hsp_query-from>43</Hsp_query-from>
      <Hsp_query-to>675</Hsp_query-to>
      <Hsp_hit-from>626</Hsp_hit-from>
      <Hsp_hit-to>835</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>222</Hsp_align-len>
      <Hsp_qseq>LGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQERESRVLAELDHPNIVRLLAVEEESVTRHRV-VVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFD-TARWLEDGEQFVSLCGTEEYLP------RAYHATVDLWSIGVTIYHVATGCLPW---AQLQELLSGLTGVTPDLQ</Hsp_qseq>
      <Hsp_hseq>IGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKK-ELIINEILVMKGSKHPNIVNFI---DSYVLKGDLWVIMEYMEGGSLTDVVTH----CILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGD----IKLTDFGFCAQINELNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPPYLNETPLRALYLIATNGTPKLK</Hsp_hseq>
      <Hsp_midline>+G+G++G VY      T    AIK ++++   +  EL   E  V+    HPNIV  +   +  V +  + V+ME   GGSL  ++        L+E     V  + ++G+  L  KG++HRD+K  NI+ +   D     KLTDF   A+  E   +  ++ GT  ++       + Y   VD+WS+G+ I  +  G  P+     L+ L    T  TP L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.7886</Hsp_bit-score>
      <Hsp_score>177</Hsp_score>
      <Hsp_evalue>3.97715e-14</Hsp_evalue>
      <Hsp_query-from>160</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>99</Hsp_hit-from>
      <Hsp_hit-to>252</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>163</Hsp_align-len>
      <Hsp_qseq>RESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFD-TARWLEDGEQFVSLCGTEEYL-------PRAYHA-TVDLWSIGVTIYHVATGCLPW</Hsp_qseq>
      <Hsp_hseq>REINALKHLSHPNIVKLEEVLQNS--RYIGIVLEYACGGEFYKYI---QKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLL----LDKNENLVITDFGFVNEFCSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPW</Hsp_hseq>
      <Hsp_midline>RE   L  L HPNIV+L  V + S  R+  +V+E   GG  +  +   +    L E +  ++ S +++G++++  KG+VHRDLK  N++     D      +TDF     +    E   + CG+  Y           Y A   D+WS GV +Y +  G LPW</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>4.34024e-14</Hsp_evalue>
      <Hsp_query-from>16</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>46</Hsp_hit-from>
      <Hsp_hit-to>249</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>213</Hsp_align-len>
      <Hsp_qseq>NFTWSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVL---SVDGMRRPPELQERESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHS-ILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGEQFVSLCG------TEEYLPRAYHAT-VDLWSIGVTIYHVATGCLPW</Hsp_qseq>
      <Hsp_hseq>NYIFGRT--LGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFY--IVTQLATGGELFDRILSRGK----FTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSEN-SPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSPF</Hsp_hseq>
      <Hsp_midline>N+ +  T  LG GS G V   R  +T    AIK+L   ++ G     ++   E  +L +L HPNIV      E     +  +V ++ +GG L   IL+  +     +E D ++++  ++  + ++  K +VHRDLKP N++   +++  +   + DF  A+ L+  E  +            E L +  H    D+WSIGV  Y +  G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>9.13676e-14</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>347</Hsp_hit-from>
      <Hsp_hit-to>545</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>208</Hsp_align-len>
      <Hsp_qseq>WSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQER--ESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARW-LEDGEQFVSLCGTEEYL-PR-----AYHATVDLWSIGVTIYHVATGCLPW</Hsp_qseq>
      <Hsp_hseq>FDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLY--FVLAFINGGELFYHLQK-EGRFDLSRARFYT--AELLCALDNLHKLDVVYRDLKPENIL----LDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPY</Hsp_hseq>
      <Hsp_midline>+ L  V+G+GS G V   R + T    A+K +    +    E+     E  VLA +D P IV L    +     +   V+   +GG L   L + E  + LS   F    ++++  +++L +  +V+RDLKP NI+     D +    L DF   +  ++D ++  + CGT EYL P       Y   VD W++GV +Y + TG  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.8626</Hsp_bit-score>
      <Hsp_score>172</Hsp_score>
      <Hsp_evalue>1.17809e-13</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>675</Hsp_query-to>
      <Hsp_hit-from>219</Hsp_hit-from>
      <Hsp_hit-to>441</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>234</Hsp_align-len>
      <Hsp_qseq>VLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQE---RESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYG-LSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGEQFVSLC----GTEEYLP------RAYHATVDLWSIGVTIYHVATGCLPWAQLQ--------ELLSGLTGVTPDLQ</Hsp_qseq>
      <Hsp_hseq>ILGEGAGGSVAKCRLKNGKKVFALK--TINTMNTDPEYQKQIFRELQFNKSFKSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNIL----LNEKGEIKLCDFGVS-----GEAVNSLAMTFTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRFPFESDKITQNVAPIELLTMILTFSPQLK</Hsp_hseq>
      <Hsp_midline>+LG G+ G V   R +      A+K  +++ M   PE Q+   RE +         IV+   +  +  +    + ME   G SL +         G +SE    ++   V+ G+++L E+ ++HRD+KP NI+     + K   KL DF  +     GE   SL     GT  Y+       + Y  T D+WS+G+T+  VA G  P+   +        ELL+ +   +P L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>1.6201e-13</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>609</Hsp_query-to>
      <Hsp_hit-from>42</Hsp_hit-from>
      <Hsp_hit-to>235</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>202</Hsp_align-len>
      <Hsp_qseq>VLGRGSTGCVYHGRHRTTGAPSAIKVL---SVDGMRRPPELQERESRVLAELDHPNIVRLLAVEEESVTRHRV-VVMEVCSGGSLHS-ILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGEQF-------VSLCGTEEYLPRAYHATVDLWSIGVTIYHVATG</Hsp_qseq>
      <Hsp_hseq>TLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIV---AFKDWFESKDKFYIITQLAKGGELFDRILKKGK----FTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSD-ESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCG</Hsp_hseq>
      <Hsp_midline> LG G+ G V   ++  TG   A+K+L   ++ G +   E    E  +L  L HPNIV   A ++   ++ +  ++ ++  GG L   IL + +     +E+D +++L ++++ + ++  + IVHRDLKP N++   ++D ++   + DF  A+ L+  E+        +     E      +    D+WSIGV  Y +  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>3.71611e-13</Hsp_evalue>
      <Hsp_query-from>136</Hsp_query-from>
      <Hsp_query-to>672</Hsp_query-to>
      <Hsp_hit-from>495</Hsp_hit-from>
      <Hsp_hit-to>677</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>193</Hsp_align-len>
      <Hsp_qseq>RRPPELQERESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLS-DVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWL----EDGEQFVSLCGT------EEYLPRAYHATVDLWSIGVTIYHVATGCLP---WAQLQELLSGLTGVTPDL</Hsp_qseq>
      <Hsp_hseq>RKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLN--IFLEYVPGGSVSSMLNN----YGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANIL----IDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKIGTNTTPEI</Hsp_hseq>
      <Hsp_midline>R+  +  + E  +L EL H NIV      +E    +  + +E   GGS+ S+LN     YG  E+  +   +  ++ G+ +L +K I+HRD+K  NI+     D K   K+TDF  ++ L    +   +  SL G+      E     A  A  D+WS G  +  + TG  P   ++Q+Q +    T  TP++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.3218</Hsp_bit-score>
      <Hsp_score>168</Hsp_score>
      <Hsp_evalue>5.41348e-13</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>417</Hsp_hit-from>
      <Hsp_hit-to>612</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>207</Hsp_align-len>
      <Hsp_qseq>VLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQER--ESRVL---AELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARW-LEDGEQFVSLCGTEEYLP-------RAYHATVDLWSIGVTIYHVATGCLPW</Hsp_qseq>
      <Hsp_hseq>LLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLY--LVTDYMSGGELFWHLQKEGR---FSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENIL----LDANGNIALCDFGLSKADLKDRTN--TFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPF</Hsp_hseq>
      <Hsp_midline>+LG+G+ G VY  + + T    A+KVLS   + +  E+     E  +L   A    P IV L    +     +  +V +  SGG L   L +       SED     ++++V  + HL +  IV+RDLKP NI+     D      L DF  ++  L+D     + CGT EYL          Y   VD WS+GV I+ +  G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>1.41012e-12</Hsp_evalue>
      <Hsp_query-from>163</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>129</Hsp_hit-from>
      <Hsp_hit-to>281</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>162</Hsp_align-len>
      <Hsp_qseq>ESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWL-EDGEQFVSLCGTEEYLP--------RAYHATVDLWSIGVTIYHVATGCLPW</Hsp_qseq>
      <Hsp_hseq>EIQIHKSMSHPNIVQFIDCFEDDSNVY--ILLEICPNGSLMELLKRRK---VLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIF----FDSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPF</Hsp_hseq>
      <Hsp_midline>E ++   + HPNIV+ +   E+    +  +++E+C  GSL  +L   +    L+E +     + +   + ++  + ++HRDLK GNI      D     K+ DF  A  L  + E+  ++CGT  Y+           +   VD+WS+GV +Y +  G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>1.51163e-12</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>702</Hsp_query-to>
      <Hsp_hit-from>179</Hsp_hit-from>
      <Hsp_hit-to>414</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>248</Hsp_align-len>
      <Hsp_qseq>WSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQ--ERESRVLAELDH-PNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYG-LSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGEQFV------------SLCGTEEYL-PRAYHATV-----DLWSIGVTIYHVATGCLPWAQLQELLSGLTGVTPDLQLFFNEGRPL</Hsp_qseq>
      <Hsp_hseq>FKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLY--FLLEYAPNGDFLSLMKK----YGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENIL----LDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVM--KVQYAFTPGFPL</Hsp_hseq>
      <Hsp_midline>+    V+G G+   V       T    A KVL+ + + R  +++    E   L +L++ P++VRL +  ++  + +   ++E    G   S++ +    YG L E       + ++  +++L   GI+HRD+KP NI+     DG+   KLTDF TA+ L      V            S  GT EY+ P   + +      D+W+ G  ++ +  G  P+    E L+    +   +Q  F  G PL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>3.5873e-12</Hsp_evalue>
      <Hsp_query-from>106</Hsp_query-from>
      <Hsp_query-to>675</Hsp_query-to>
      <Hsp_hit-from>592</Hsp_hit-from>
      <Hsp_hit-to>789</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>207</Hsp_align-len>
      <Hsp_qseq>AIKVLSVDGMRRPPELQERESRVLAELDHPNIVRLLAVEEESVTRHRV---VVMEVCSGGSLHSIL-NEPENAYG---LSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFD-TARWLEDGEQFVSLCGTEEYLP------RAYHATVDLWSIGVTIYHVATGCLPWAQ---LQELLSGLTGVTPDLQ</Hsp_qseq>
      <Hsp_hseq>AIKQMVLSKQPRK-ELIVNEILVMKDSRHKNIVNFL----EAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVL----LDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATNGTPKLK</Hsp_hseq>
      <Hsp_midline>AIK + +    R  EL   E  V+ +  H NIV  L    E+  R      VVME   GGSL  I+ N P N      L+E     ++ +   G+  L +K I+HRD+K  N++     D +A  K+TDF   AR  +   +  ++ GT  ++       R Y   +D+WS+G+    +  G  P+     L+ L    T  TP L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>3.61008e-12</Hsp_evalue>
      <Hsp_query-from>43</Hsp_query-from>
      <Hsp_query-to>609</Hsp_query-to>
      <Hsp_hit-from>13</Hsp_hit-from>
      <Hsp_hit-to>205</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>200</Hsp_align-len>
      <Hsp_qseq>LGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQERESRVLAELDHPNIVRLLAV---EEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLE-DGEQFVSLCGTEEYL-------PRAYHATVDLWSIGVTIYHVATG</Hsp_qseq>
      <Hsp_hseq>LGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPR---GLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLL----INKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITG</Hsp_hseq>
      <Hsp_midline>LG G+   VY G ++TTG   A+K + +D     P    RE  ++ EL H NIVRL  V   E +       +  ++       ++ N P    GL  +        ++ G+    E  I+HRDLKP N++     + +   KL DF  AR        F S   T  Y         R Y  ++D+WS G  +  + TG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>5.93684e-12</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>636</Hsp_query-to>
      <Hsp_hit-from>120</Hsp_hit-from>
      <Hsp_hit-to>361</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>248</Hsp_align-len>
      <Hsp_qseq>TWSLTDVLGRGSTGCVYH--GRHRTTGAPSAIKVL---------------SVDGMRRPPELQERESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRA----FRADG----------------KATYKLTDFDTARWLEDGEQFVSLCGTEEYL------PRAYHATVDLWSIGVTIYHVATGCLPWAQLQE</Hsp_qseq>
      <Hsp_hseq>NYKLLNKIGEGAFSRVFKAVGINTDDQAPVAIKAIIKKGISSDAILKGNDRIQGSSRKKVLNEVAIHKLVSKNNPHCTKFIAFQESA--NYYYLVTELVTGGE---IFDRIVQLTCFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLRNNTA-KTPCGTIEYVASEVFTSKRYSMKVDMWSIGCVLFTLLCGYPPFYEKNE</Hsp_hseq>
      <Hsp_midline> + L + +G G+   V+   G +    AP AIK +                + G  R   L E     L   ++P+  + +A +E +   +  +V E+ +GG    I +        SED    V++ V   + H+   GIVHRD+KP N++      +  DG                    KL DF  A+ L +     + CGT EY+       + Y   VD+WSIG  ++ +  G  P+ +  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>7.61003e-12</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>699</Hsp_query-to>
      <Hsp_hit-from>360</Hsp_hit-from>
      <Hsp_hit-to>600</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>258</Hsp_align-len>
      <Hsp_qseq>WSLTDVLGRGSTGCVYHGR-----------------HRTTGAPSAIKVLSVDGMRRPPELQERESRVLAELDHPNIVRLL---AVEEESVTRHRVVVMEVCSGGSLHSIL------NEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWL-EDGEQFVSLCGTEEYLP------RAYHATVDLWSIGVTIYHVATGCLPWAQLQELLSGLTGVTPDLQLFFNEGRP</Hsp_qseq>
      <Hsp_hseq>FQLVEKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQPKK-QLIMNELLVMNDSRQENIVNFLEAYIIDDEELW----VIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNIL----LNSQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKA--------LYLIANNGSP</Hsp_hseq>
      <Hsp_midline>+ L +  G+G++G VY  +                 HR  G   AIK + +    +  +L   E  V+ +    NIV  L    +++E +     V+ME   GG L  IL      N  E++  L+E+    ++ +   G+  L  K I+HRD+K  NI+     + +   K+TDF     L E   +  ++ GT  ++       + Y   VD+WS+G+ +  +  G  P+     L +        L L  N G P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>9.18699e-12</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>99</Hsp_hit-from>
      <Hsp_hit-to>323</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>235</Hsp_align-len>
      <Hsp_qseq>WSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVL------------SVDGMRRPPELQERESRVLAE----------------LDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYG-LSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGEQFVSLCGTEEY----LPRAYHAT---VDLWSIGVTIYHVATGCLPW</Hsp_qseq>
      <Hsp_hseq>WEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESEILERQKRLEKEIARDKRTVREASLGQILYHPHICRLF--EMCTMSNHFYMLFEYVSGGQLLDYIIQ----HGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIM----ISSSGEIKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPF</Hsp_hseq>
      <Hsp_midline>W   + +G GS G V   +HR T     IK++            S+   +   E+ ER+ R+  E                L HP+I RL   E  +++ H  ++ E  SGG L   + +    +G L E    +    + + + +L    IVHRDLK  NIM           K+ DF  +   +  +Q  + CG+  +    L +A   T   VD+WS G+ +Y +  G +P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>9.56186e-12</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>120</Hsp_hit-from>
      <Hsp_hit-to>344</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>235</Hsp_align-len>
      <Hsp_qseq>WSLTDVLGRGSTGCVYHGRHRTTGAPSAIKV--------LSVDGMRRPPELQE--------------RESRVLAE------LDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYG-LSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGEQFVSLCGTEEY-LPRAYHAT------VDLWSIGVTIYHVATGCLPW</Hsp_qseq>
      <Hsp_hseq>WEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPPPKNEQDVLERQKKLEKEISRDKRTIREASLGQILYHPHICRLF--EMCTLSNHFYMLFEYVSGGQLLDYIIQ----HGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIM----ISDSSEIKIIDFGLSNIYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPF</Hsp_hseq>
      <Hsp_midline>W   + +G GS G V   +HR T    A+K+        L  + M  PP+ ++              R+ R + E      L HP+I RL   E  +++ H  ++ E  SGG L   + +    +G + E    +    + + + +L    IVHRDLK  NIM        +  K+ DF  +   +  +Q  + CG+  +  P    A       VD+WS GV ++ +  G +P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>1.4433e-11</Hsp_evalue>
      <Hsp_query-from>31</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>17</Hsp_hit-from>
      <Hsp_hit-to>222</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>222</Hsp_align-len>
      <Hsp_qseq>LTDVLGRGSTGCVYHGRH----------RTTGAPSAIKV-LSVDGMRRPPELQERESRVLAELDHPNIVRLLAVEEESVTRHRV-VVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLR-EKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWL--EDGEQFVSLC--GTEEYLP-------RAYHAT-VDLWSIGVTIYHVATGCLPW</Hsp_qseq>
      <Hsp_hseq>LGDTVGQGAFACVKNAHLQMDPSIILAVKFIHVPTCKKMGLSDKDITKEVVLQSKCSK------HPNVLRLIDC---NVSKEYMWIILEMADGGDLFDKI-EPD--VGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENIL----LDKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQTPW</Hsp_hseq>
      <Hsp_midline>L D +G+G+  CV +             +    P+  K+ LS   + +   LQ + S+      HPN++RL+     +V++  + +++E+  GG L   + EP+   G+  D        +V+ +N+L  E G+ HRD+KP NI+     D     KL DF  A     +DG   VS+   G+  Y+          Y+A   D+WSIG+ ++ + TG  PW</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YFL033C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:69115:74427:-1 gene:YFL033C transcript:YFL033C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM15 description:Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase [Source:SGD;Acc:S000001861]</Hit_def>
  <Hit_accession>YFL033C</Hit_accession>
  <Hit_len>1770</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>1.92797e-11</Hsp_evalue>
      <Hsp_query-from>43</Hsp_query-from>
      <Hsp_query-to>486</Hsp_query-to>
      <Hsp_hit-from>800</Hsp_hit-from>
      <Hsp_hit-to>941</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>152</Hsp_align-len>
      <Hsp_qseq>LGRGSTGCVYHGRHRTTGAPSAIKVLSVDGM---RRPPELQERESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFL-QVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTAR</Hsp_qseq>
      <Hsp_hseq>ISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDKPYVARLFASFQNK--DNLFLVMEYLPGGDLATLIK----MMGYLPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLL----IDNAGHVKLTDFGLSR</Hsp_hseq>
      <Hsp_midline>+ +G+ G VY  R + TG   AIKVL    M    +   ++   + ++ + D P + RL A  +     +  +VME   GG L +++       G   D +  Q L+++V G+N + + GI+H DLKP N++     D     KLTDF  +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>1.93279e-11</Hsp_evalue>
      <Hsp_query-from>43</Hsp_query-from>
      <Hsp_query-to>582</Hsp_query-to>
      <Hsp_hit-from>189</Hsp_hit-from>
      <Hsp_hit-to>368</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>190</Hsp_align-len>
      <Hsp_qseq>LGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRP-PELQERESRVLAELDHPNI--VRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGEQFVSLCGTEEYLP-------RAYHATVDLWSIG</Hsp_qseq>
      <Hsp_hseq>VGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNVSTIKEIMVESQKTV---YMIFEYADNDLSGLLLNK---EVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNIL----IDNQGNLKITDFGLARKMNSRADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCG</Hsp_hseq>
      <Hsp_midline>+G G+ G VY  ++  T    A+K L + G R   P    RE ++L   DHPN+  ++ + VE +       ++ E         +LN+      +S      +   ++ GM +L +  I+HRD+K  NI+     D +   K+TDF  AR +     + +   T  Y P         Y   VD+W  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>2.32288e-11</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>34</Hsp_hit-from>
      <Hsp_hit-to>232</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>214</Hsp_align-len>
      <Hsp_qseq>QLSENFTWSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQERESRVLAELDHPNIVRLLAVEEESVTRHRV-VVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGEQFVSLCGTEEYLP------RAYHA-TVDLWSIGVTIYHVATGCLPW</Hsp_qseq>
      <Hsp_hseq>ELTEVGNYKILKQIGEGSFGKVYLALHR----PTHRKVCLKTSDKNDPNIV-REVFYHRQFDFPYITKLYEV---IVTESKVWMALEYCPGKELY---DHLLSLRRISLLECGELFAQISGAVYYAHSMHCVHRDLKLENIL----LDKNGNAKLTDFGFTRECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPF</Hsp_hseq>
      <Hsp_midline>+L+E   + +   +G GS G VY   HR    P+  KV      +  P +  RE     + D P I +L  V    VT  +V + +E C G  L+   +   +   +S  +  ++ + +   + +      VHRDLK  NI+     D     KLTDF   R         ++CGT  Y+       R Y    +D+WS+GV +Y + TG LP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>3.86094e-11</Hsp_evalue>
      <Hsp_query-from>37</Hsp_query-from>
      <Hsp_query-to>636</Hsp_query-to>
      <Hsp_hit-from>320</Hsp_hit-from>
      <Hsp_hit-to>534</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>223</Hsp_align-len>
      <Hsp_qseq>DVLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGM----RRPPELQERESRVL-------AELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTAR-----WLEDGEQFVSLCGT------EEYLPRAYHA-TVDLWSIGVTIYHVATGCLPWAQLQE</Hsp_qseq>
      <Hsp_hseq>EVLGKGAFGVVRICQKKNVSSQDGNKSEKLYAVKEFKRRTSESAEKYSKRLTSEFCISSSLHHTNIVTTLDLFQDAKGEY-CEVMEYCAGGDLFTLVVAAGKLEYMEADCFFKQL---IRGVVYMHEMGVCHRDLKPENLL--LTHDG--VLKITDFGNSECFKMAWEKNIHLSGGVCGSSPYIAPEEYIKEEFDPRPVDIWACGVIYMAMRTGRQLWSSAEK</Hsp_hseq>
      <Hsp_midline>+VLG+G+ G V   + +   +    K   +  +    RR  E  E+ S+ L       + L H NIV  L + +++   +   VME C+GG L +++        +  D F + L   + G+ ++ E G+ HRDLKP N++     DG    K+TDF  +      W ++      +CG+      EEY+   +    VD+W+ GV    + TG   W+  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>7.50845e-11</Hsp_evalue>
      <Hsp_query-from>160</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>258</Hsp_hit-from>
      <Hsp_hit-to>445</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>192</Hsp_align-len>
      <Hsp_qseq>RESRVLAELDHPNIVRLLAVEEESVTRHRV-----------------VVMEVCSGGSLHSILNEPENAYGLSEDDFLQ-VLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYK------------LTDFDTARWLEDGEQFVSLCGTEEY--------LPRAYHATVDLWSIGVTIYHVATGCLPW</Hsp_qseq>
      <Hsp_hseq>RELQVLKSLNHPCIVKLLGINNPIFVTSKKPLCDLIIKTPRALPPCDMIMSYCPAGDLLAAVMA---RNGRLEAWLIQRIFTEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLCKKIENNEMCTARCGSEDYVSPEILMGVPYDGHLS-DTWALGVILYSLFEDRLPF</Hsp_hseq>
      <Hsp_midline>RE +VL  L+HP IV+LL +        +                  ++M  C  G L + +       G  E   +Q + ++VV  + +L E  I+HRDLK  NI+  +  D   +++            L DF   + +E+ E   + CG+E+Y        +P   H + D W++GV +Y +    LP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>8.13483e-11</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>699</Hsp_query-to>
      <Hsp_hit-from>125</Hsp_hit-from>
      <Hsp_hit-to>361</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>249</Hsp_align-len>
      <Hsp_qseq>WSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQ--ERESRVLAELD-HPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYG-LSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLE-------DGEQFV-------SLCGTEEYL-PRAYH-----ATVDLWSIGVTIYHVATGCLPWAQLQELLSGLTGVTPDLQLFFNEGRP</Hsp_qseq>
      <Hsp_hseq>FKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQKLNGTKGIFKLFFTFQDEASLY--FLLEYAPHGDFLGLIKK----YGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENIL----LDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMK--IQYAFTAGFP</Hsp_hseq>
      <Hsp_midline>+   + LG GS   V     R +G   A+KVLS + + R  +++    E   L +L+    I +L    ++  + +   ++E    G    ++ +    YG L+E       S ++  ++ L   GI+HRD+KP NI+     D     KLTDF TA+ L        DG+ +        S  GT EY+ P   +     +  D+W+ G  +Y +  G  P+    E L+    +   +Q  F  G P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>1.54815e-10</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>81</Hsp_hit-from>
      <Hsp_hit-to>315</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>54</Hsp_gaps>
      <Hsp_align-len>244</Hsp_align-len>
      <Hsp_qseq>WSLTDVLGRGSTGCVYHGRHRTTGAPSAIKV-----------------------LSVDGMRRP--------------PELQERESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGK-ATYKLTDFDTARWLEDGEQFVSLCGTEEY------LPRAYH-ATVDLWSIGVTIYHVATGCLPW</Hsp_qseq>
      <Hsp_hseq>WKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELY--LVLEYVDGGELFDYLVSKGK---LPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLL----LDKKNRRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPF</Hsp_hseq>
      <Hsp_midline>W L   LG+GS+G V   ++  TG  +AIK+                       +    +  P              P   ERE  ++  + H N++ L  V E     +  +V+E   GG L   L        L E + +     +V G+++     I HRDLKP N++     D K    K+ DF  A      +   + CG+  Y      + R YH    D+WS G+ ++ + TG LP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>1.63052e-10</Hsp_evalue>
      <Hsp_query-from>37</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>364</Hsp_hit-from>
      <Hsp_hit-to>564</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>215</Hsp_align-len>
      <Hsp_qseq>DVLGRGSTGCVYHGRHRTTGAPSAIKV--LSVDGMRRPPELQERESRVLAELDHPNIVRLLAVE--EESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREK-GIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGEQFVSLC----GTEEYLP----------RA-YHATVDLWSIGVTIYHVATGCLPW</Hsp_qseq>
      <Hsp_hseq>DELGHGNYGNVSKVLHKPTNVIMATKEVRLELDEAKFRQILMELE--VLHKCNSPYIVDFYGAFFIEGAV----YMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSA---NQGTVKLCDFGVS-----GNLVASLAKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPY</Hsp_hseq>
      <Hsp_midline>D LG G+ G V    H+ T    A K   L +D  +    L E E  VL + + P IV        E +V     + ME   GGSL  I +E     G+ E     + + V+ G+  L+E+  I+HRD+KP NI+ +     + T KL DF  +     G    SL     G + Y+           RA Y    D+WS+G++I  +A G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>1.96604e-10</Hsp_evalue>
      <Hsp_query-from>142</Hsp_query-from>
      <Hsp_query-to>648</Hsp_query-to>
      <Hsp_hit-from>1147</Hsp_hit-from>
      <Hsp_hit-to>1313</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>179</Hsp_align-len>
      <Hsp_qseq>PPELQERESRVLAELD---HPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGEQFVSLCGTEEY-LPRAYHAT------VDLWSIGVTIYHVATGCLPWAQLQELLSG</Hsp_qseq>
      <Hsp_hseq>PSEIQ-----IMATLNKKPHENILRLLDFFEDD--DYYYIETPVHGETGCIDLFDLIEFKTNMTEFEAKLIFKQVVAGIKHLHDQGIVHRDIKDENVI----VDSKGFVKIIDFGSAAYVKSGP-FDVFVGTIDYAAPEVLGGNPYEGQPQDIWAIGILLYTVVFKENPFYNIDEILEG</Hsp_hseq>
      <Hsp_midline>P E+Q     ++A L+   H NI+RLL   E+    +  +   V        + +  E    ++E +   +   VVAG+ HL ++GIVHRD+K  N++     D K   K+ DF +A +++ G  F    GT +Y  P             D+W+IG+ +Y V     P+  + E+L G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>2.11732e-10</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>648</Hsp_query-to>
      <Hsp_hit-from>841</Hsp_hit-from>
      <Hsp_hit-to>1058</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>227</Hsp_align-len>
      <Hsp_qseq>WSLTDVLGRGSTG----CVYHGRHRTTGAPSAIKV-LSVDGMRRPPELQE--RESRVLAELD---HPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSI--LNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGEQFVSLCGTEEY-LPRAYHATV------DLWSIGVTIYHVATGCLPWAQLQELLSG</Hsp_qseq>
      <Hsp_hseq>FTILQVMGEGAYGKVNLCIHNREHYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKNSQENILKLLDFFEDDDYYY----IETPVHGETGSIDLFDVIEFKKDMVEHEAKLVFKQVVASIKHLHDQGIVHRDIKDENVI----VDSHGFVKLIDFGSAAYIKSG-PFDVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLYTIIYKENPYYNIDEILEG</Hsp_hseq>
      <Hsp_midline>+++  V+G G+ G    C+++  H         K  + VD   R  +L     E +++A L+     NI++LL   E+    +    +E    G   SI   +  E    + E +   V   VVA + HL ++GIVHRD+K  N++     D     KL DF +A +++ G  F    GT +Y  P     +       D+W++GV +Y +     P+  + E+L G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>5.11947e-10</Hsp_evalue>
      <Hsp_query-from>43</Hsp_query-from>
      <Hsp_query-to>699</Hsp_query-to>
      <Hsp_hit-from>197</Hsp_hit-from>
      <Hsp_hit-to>427</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>241</Hsp_align-len>
      <Hsp_qseq>LGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQ-ERESRVLAELD-HPNIVRLL-AVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYG----------LSEDDFLQVLSDVVAGMNHL-REKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLED--GEQFVSLCGTEEYLP------RAYHATVDLWSIGVTIYHVATGCLPWAQLQELLSGLTGVTPDLQLFFNEGRP</Hsp_qseq>
      <Hsp_hseq>IGAGNSGTVVKALHVPDSKIVAKKTIPVEQNNSTIINQLVRELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVL----INSKGQIKLCDFGVSKKLINSIADTFV---GTSTYMSPERIQGNVYSIKGDVWSLGLMIIELVTGEFPLGGHNDTPDGILDL---LQRIVNEPSP</Hsp_hseq>
      <Hsp_midline>+G G++G V    H       A K + V+        Q  RE  ++  +  H NI+    A   + +    +++ME    GSL  IL+  +               +E    ++   V+ G++HL R+  I+HRD+KP N++     + K   KL DF  ++ L +   + FV   GT  Y+         Y    D+WS+G+ I  + TG  P     +   G+  +   LQ   NE  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>1.04532e-09</Hsp_evalue>
      <Hsp_query-from>157</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>190</Hsp_hit-from>
      <Hsp_hit-to>379</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>195</Hsp_align-len>
      <Hsp_qseq>ERESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLH-----SILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDF---------------------DTARWLEDGEQFV-SLCGTEEYLPRAYHAT-------------VDLWSIGVTIYHVATGCLPW</Hsp_qseq>
      <Hsp_hseq>KREIAIMKKCHHKHVVQLIEVLDDLKSRKIYLVLEYCSRGEVKWCPPDCMESDAKGPSLLSFQETREILRGVVLGLEYLHYQGIIHRDIKPANLL----ISGDGTVKISDFGVSLAASSTNSSDSSESLDELELAKTVGTPAFFAPEMCLGEDAFTR-YNLTKENLFRGSCISFMIDIWAVGVTLYCLLFGMLPF</Hsp_hseq>
      <Hsp_midline>+RE  ++ +  H ++V+L+ V ++  +R   +V+E CS G +       + ++ +    LS  +  ++L  VV G+ +L  +GI+HRD+KP N++      G  T K++DF                     + A+ +     F   +C  E+   R Y+ T             +D+W++GVT+Y +  G LP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>1.36209e-09</Hsp_evalue>
      <Hsp_query-from>163</Hsp_query-from>
      <Hsp_query-to>624</Hsp_query-to>
      <Hsp_hit-from>202</Hsp_hit-from>
      <Hsp_hit-to>363</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>ESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYG-LSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDF--------DTARWLEDGEQ---FVSLCGTEEY------LPRAYHATVDLWSIGVTIYHVATGCLPWA</Hsp_qseq>
      <Hsp_hseq>ERSILSEIEHPNIVKLFYSFHDNSKLY--LLLQYIPGGELFYHLKE----HGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCL----LNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYT</Hsp_hseq>
      <Hsp_midline>E  +L+E++HPNIV+L     ++   +  ++++   GG L   L E    +G L E       +++   +  L  KG+V+RDLKP N +     + +    LTDF        D+A   ED E      S+ GT EY      L +AY    D +S+G  +Y +  G  P+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>2.22001e-09</Hsp_evalue>
      <Hsp_query-from>16</Hsp_query-from>
      <Hsp_query-to>591</Hsp_query-to>
      <Hsp_hit-from>4</Hsp_hit-from>
      <Hsp_hit-to>195</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>201</Hsp_align-len>
      <Hsp_qseq>NFTWSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQE-RESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGEQFVSLCGTEEYL--------PRAYHATVDLWSIGVTI</Hsp_qseq>
      <Hsp_hseq>NMEYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNVIELIDIFMAYDNLN--LVLEFLPT-DLEVVIKD--KSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLL--FSPDGQI--KVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIF</Hsp_hseq>
      <Hsp_midline>N  ++    +G G+   VY G   +TG   AIK +     +   ++   RE + L E+ HPN++ L+ +       +  +V+E      L  ++ +   +   +  D    +   + G+ H     I+HRDLKP N++  F  DG+   K+ DF  AR +    + ++      +          + Y + +D+WS+GV  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>2.28627e-09</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>609</Hsp_query-to>
      <Hsp_hit-from>13</Hsp_hit-from>
      <Hsp_hit-to>222</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>214</Hsp_align-len>
      <Hsp_qseq>WSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQERESRVLAEL-DHPNIVRLL-AVEEESVTR-HRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLS-DVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWL---EDGEQFVSLCGTEEYLPRAYHA------------TVDLWSIGVTIYHVATG</Hsp_qseq>
      <Hsp_hseq>YKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLL----LNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSG</Hsp_hseq>
      <Hsp_midline>+ L D++G G+ G V    H+ +G   AIK +     +       RE ++L    +H NI+ +L  V   S+ + + V ++E      L  ++N   + +    DD +Q  +  ++  +  +    ++HRD+KP N++     +     K+ DF  AR L    D  + +    TE    R Y A             +D+WS G  +  + +G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YPL204W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:164276:165760:1 gene:YPL204W transcript:YPL204W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRR25 description:Conserved casein kinase; regulates diverse events including: vesicular traffic, DNA repair, the CVT pathway, monopolar attachment of sister kinetochores at meiosis I, and ribosomal subunit biogenesis; monopolin subunit; binds the RNAPII CTD; phosphorylates COPII coat subunits; interacts with Sit4p phosphatase; antagonizes calcineurin signaling, reducing nuclear accumulation of Crz1p; phosphorylates Dsn1p, the kinetochore receptor for monopolin; homolog of mammalian CK1delta [Source:SGD;Acc:S000006125]</Hit_def>
  <Hit_accession>YPL204W</Hit_accession>
  <Hit_len>494</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>3.67136e-09</Hsp_evalue>
      <Hsp_query-from>43</Hsp_query-from>
      <Hsp_query-to>633</Hsp_query-to>
      <Hsp_hit-from>15</Hsp_hit-from>
      <Hsp_hit-to>217</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>215</Hsp_align-len>
      <Hsp_qseq>LGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQERESRVLAELDH----PNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATY--------KLTDFDTARWLEDGEQFVSLCGTEEYLPRAYHATV------DLWSIGVTIYHVATGCLPWAQLQ</Hsp_qseq>
      <Hsp_hseq>IGSGSFGDIYHGTNLISGEEVAIKLESIRS--RHPQL-DYESRVYRYLSGGVGIP-FIRWFGREGE----YNAMVIDLL-GPSLEDLFNYCHRRFSFKTVIMLAL--QMFCRIQYIHGRSFIHRDIKPDNFLMGVGRRGSTVHVIDFGLSKKYRDFNTHRHIPYREN-KSLTGTARYASVNTHLGIEQSRRDDLESLGYVLIYFCKGSLPWQGLK</Hsp_hseq>
      <Hsp_midline>+G GS G +YHG +  +G   AIK+ S+    R P+L + ESRV   L      P  +R    E E    +  +V+++  G SL  + N     +       L +   +   + ++  +  +HRD+KP N +      G   +        K  DF+T R +   E   SL GT  Y     H  +      DL S+G  + +   G LPW  L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YHR079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:258244:261591:-1 gene:YHR079C transcript:YHR079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IRE1 description:Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; role in homeostatic adaptation to ER stress; Kar2p binds inactive Ire1p and releases from it upon ER stress [Source:SGD;Acc:S000001121]</Hit_def>
  <Hit_accession>YHR079C</Hit_accession>
  <Hit_len>1115</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>4.08646e-09</Hsp_evalue>
      <Hsp_query-from>16</Hsp_query-from>
      <Hsp_query-to>504</Hsp_query-to>
      <Hsp_hit-from>665</Hsp_hit-from>
      <Hsp_hit-to>839</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>184</Hsp_align-len>
      <Hsp_qseq>NFTWSLTD------VLGRGSTG-CVYHGRHRTTGAPSAIKVLSVDGMRRPPELQERESRVLAELD-HPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEP----ENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRA----FRADGKATYK-----LTDFDTARWLEDGE</Hsp_qseq>
      <Hsp_hseq>NFEQSLKNLVVSEKILGYGSSGTVVFQGSFQ--GRPVAVKRMLIDFC----DIALMEIKLLTESDDHPNVIRYYC--SETTDRFLYIALELCNL-NLQDLVESKNVSDENLKLQKEYNPISLLRQIASGVAHLHSLKIIHRDLKPQNILVSTSSRFTADQQTGAENLRILISDFGLCKKLDSGQ</Hsp_hseq>
      <Hsp_midline>NF  SL +      +LG GS+G  V+ G  +  G P A+K + +D      ++   E ++L E D HPN++R      E+  R   + +E+C+  +L  ++       EN     E + + +L  + +G+ HL    I+HRDLKP NI+ +    F AD +   +     ++DF   + L+ G+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>6.98624e-09</Hsp_evalue>
      <Hsp_query-from>43</Hsp_query-from>
      <Hsp_query-to>684</Hsp_query-to>
      <Hsp_hit-from>41</Hsp_hit-from>
      <Hsp_hit-to>265</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>237</Hsp_align-len>
      <Hsp_qseq>LGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQERESRVLAELDHPNIVRL------LAVEEESVTRHRVVVMEVCSGGSLHSILNE-PENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGK-ATYKLTDFDTARWLEDGEQFVSLCGTEEYLPRA---------YHATVDLWSIGVTI------YHVATGCLPWAQLQELLSGLTGVTPDLQLFF</Hsp_qseq>
      <Hsp_hseq>IGRGAFGTVVQA-YLTQDKKNWLGPFAIKKVPAHTEYKSRELQILRIADHPNIVKLQYFFTHLSPQDNKVYQH--LAME-CLPETLQIEINRYVTNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVL----VDPETGVLKICDFGSAKKLEHNQPSISYICSRFY--RAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLRE-IAKLLG-PPDKRFIF</Hsp_hseq>
      <Hsp_midline>+GRG+ G V    + T    + +   ++  +    E + RE ++L   DHPNIV+L      L+ ++  V +H  + ME C   +L   +N    N   +           +  GM +L   G+ HRD+KP N++     D +    K+ DF +A+ LE  +  +S   +  Y  RA         Y   +D+W +G  +        +  G  P  QL+E ++ L G  PD +  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>1.01866e-08</Hsp_evalue>
      <Hsp_query-from>13</Hsp_query-from>
      <Hsp_query-to>624</Hsp_query-to>
      <Hsp_hit-from>173</Hsp_hit-from>
      <Hsp_hit-to>416</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>62</Hsp_gaps>
      <Hsp_align-len>255</Hsp_align-len>
      <Hsp_qseq>ENFTWSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPE----LQERESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFD-----------------------------TARWLEDGEQFV------------SLCGTEEYLP------RAYHATVDLWSIGVTIYHVATGCLPWA</Hsp_qseq>
      <Hsp_hseq>KNRDFEMITQVGQGGYGQVYLARKKDTKEVCALKILNKKLLFKLNETKHVLTERD--ILTTTRSEWLVKLLYAFQDLQSLY--LAMEFVPGGDFRTLL---INTRCLKSGHARFYISEMFCAVNALHDLGYTHRDLKPEN----FLIDAKGHIKLTDFGLAAGTISNERIESMKIRLEKIKDLEFPAFTEKSIEDRRKMYNQLREKEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFS</Hsp_hseq>
      <Hsp_midline>+N  + +   +G+G  G VY  R + T    A+K+L+   + +  E    L ER+  +L       +V+LL   ++  + +  + ME   GG   ++L    N   L        +S++   +N L + G  HRDLKP N    F  D K   KLTDF                              T + +ED  +              S+ G+ +Y+       + Y  TVD WS+G  ++    G  P++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>1.11352e-08</Hsp_evalue>
      <Hsp_query-from>13</Hsp_query-from>
      <Hsp_query-to>624</Hsp_query-to>
      <Hsp_hit-from>822</Hsp_hit-from>
      <Hsp_hit-to>1025</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>219</Hsp_align-len>
      <Hsp_qseq>ENFTWSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQ----ERESRVLA-ELDHPNIVRLLAVEEESVTRHRV-VVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTAR---WLEDGEQFVSLCGTEEYLP------RAYHATVDLWSIGVTIYHVATGCLPWA</Hsp_qseq>
      <Hsp_hseq>DNFV--LLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQ---TENRIYFAMEFIGGGDL--MWHVQNQRLSVRRAKF--YAAEVLLALKYFHDNGVIYRDLKLENILLT----PEGHIKIADYGLCKDEMWY--GNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFS</Hsp_hseq>
      <Hsp_midline>+NF   L  VLG+G+ G V   + + T    AIKVL  D + +  +++    E++  +LA +  HP +  L    +   T +R+   ME   GG L  + +       +    F    ++V+  + +  + G+++RDLK  NI+       +   K+ D+   +   W   G +  + CGT E++       + Y   VD W+ GV +Y +     P++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YOR267C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:822588:824867:-1 gene:YOR267C transcript:YOR267C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRK1 description:Protein kinase; implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005793]</Hit_def>
  <Hit_accession>YOR267C</Hit_accession>
  <Hit_len>759</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>1.84918e-08</Hsp_evalue>
      <Hsp_query-from>31</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>217</Hsp_hit-from>
      <Hsp_hit-to>421</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>217</Hsp_align-len>
      <Hsp_qseq>LTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPE-LQERESRVLAE------LDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTA---RW-LEDGEQFV-SLCGTEEYL-PRAYHAT-------VDLWSIGVTIYHVATGCLPW</Hsp_qseq>
      <Hsp_hseq>LGKLLGSGAGGSVKVLVRPTDGATFAVKEFRP---RKPNESVKEYAKKCTAEFCIGSTLHHPNVIETVDVFSDSKQNKYYEVMEYCPIDFFAVVM-----TGKMSRGEINCCLKQLTEGVKYLHSMGLAHRDLKLDNCVMT----SQGILKLIDFGSAVVFRYPFEDGVTMAHGIVGSDPYLAPEVITSTKSYDPQCVDIWSIGIIYCCMVLKRFPW</Hsp_hseq>
      <Hsp_midline>L  +LG G+ G V      T GA  A+K       R+P E ++E   +  AE      L HPN++  + V  +S       VME C       ++        +S  +    L  +  G+ +L   G+ HRDLK  N +       +   KL DF +A   R+  EDG      + G++ YL P    +T       VD+WSIG+    +     PW</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>6.26861e-08</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>501</Hsp_query-to>
      <Hsp_hit-from>13</Hsp_hit-from>
      <Hsp_hit-to>165</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>163</Hsp_align-len>
      <Hsp_qseq>WSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQE--RESRVLAELDHPNIVRLLAVE--EESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDG</Hsp_qseq>
      <Hsp_hseq>FQLKSLLGEGAYGVVCSATHKPTGEIVAIK--KIEPFDKPLFALRTLREIKILKHFKHENIITIFNIQRPDSFENFNEVYIIQELMQTDLHRVIS----TQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLL----INSNCDLKVCDFGLARIIDES</Hsp_hseq>
      <Hsp_midline>+ L  +LG G+ G V    H+ TG   AIK   ++   +P       RE ++L    H NI+ +  ++  +     + V +++      LH +++       LS+D     +   +  +  L    ++HRDLKP N++     +     K+ DF  AR +++ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>8.57348e-08</Hsp_evalue>
      <Hsp_query-from>43</Hsp_query-from>
      <Hsp_query-to>582</Hsp_query-to>
      <Hsp_hit-from>66</Hsp_hit-from>
      <Hsp_hit-to>270</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>216</Hsp_align-len>
      <Hsp_qseq>LGRGSTGCVYHGRHRTTGAPSAIK--VLSVDGMRRPPELQERESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGG--------------SLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLE-------------DGEQFVSLCGTEEYLP-------RAYHATVDLWSIG</Hsp_qseq>
      <Hsp_hseq>LGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQ-REITILKRLNHKNIIKLI----EMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPR--INLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANIL----IDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVG</Hsp_hseq>
      <Hsp_midline>LG+G+ G VY G H  T    A+K  ++SV+    P   Q RE  +L  L+H NI++L+    E V  H   +    S                 L  +L+ P     L   D   ++  ++ G+N++     +HRD+K  NI+     D     KL DF  AR                 G ++ S+  T  Y         + Y   VD+W +G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YPR111W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:747306:749000:1 gene:YPR111W transcript:YPR111W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF20 description:Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006315]</Hit_def>
  <Hit_accession>YPR111W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>1.38375e-07</Hsp_evalue>
      <Hsp_query-from>43</Hsp_query-from>
      <Hsp_query-to>624</Hsp_query-to>
      <Hsp_hit-from>175</Hsp_hit-from>
      <Hsp_hit-to>408</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>62</Hsp_gaps>
      <Hsp_align-len>245</Hsp_align-len>
      <Hsp_qseq>LGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPE----LQERESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFD-----------------------------TARWLEDGEQFV------------SLCGTEEYLP------RAYHATVDLWSIGVTIYHVATGCLPWA</Hsp_qseq>
      <Hsp_hseq>VGQGGYGQVYLAKKKDSDEICALKILNKKLLFKLNETNHVLTERD--ILTTTRSDWLVKLLYAFQDPESLY--LAMEFVPGGDFRTLL---INTRILKSGHARFYISEMFCAVNALHELGYTHRDLKPEN----FLIDATGHIKLTDFGLAAGTVSNERIESMKIRLEEVKNLEFPAFTERSIEDRRKIYHNMRKTEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFS</Hsp_hseq>
      <Hsp_midline>+G+G  G VY  + + +    A+K+L+   + +  E    L ER+  +L       +V+LL   ++  + +  + ME   GG   ++L    N   L        +S++   +N L E G  HRDLKP N    F  D     KLTDF                              T R +ED  +              S+ G+ +Y+       + Y  TVD WS+G  ++    G  P++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>1.42331e-07</Hsp_evalue>
      <Hsp_query-from>43</Hsp_query-from>
      <Hsp_query-to>615</Hsp_query-to>
      <Hsp_hit-from>8</Hsp_hit-from>
      <Hsp_hit-to>221</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>226</Hsp_align-len>
      <Hsp_qseq>LGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQERESRVLAELD----------HPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPEN-----AYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGK--------ATYKLTDF----DTARWLEDGEQFVS-LCGTEEY------LPRAYHATVDLWSIGVTIYHVATG-CL</Hsp_qseq>
      <Hsp_hseq>IQSGTFSTVYKAWSTTHNRYVALKI--------TPKYKTSEANMKNEYDVMKILSSCNPHPNICSMLDFYTDD--SYYIMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQIDMQKIIKQLCSAISFAHSLGIAHRDIKPENILLTINGDIKLADWGHAIQSPKSNDFQIGTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQA--DYWSLGATIFYLMFGDCL</Hsp_hseq>
      <Hsp_midline>+  G+   VY     T     A+K+         P+ +  E+ +  E D          HPNI  +L    +    + ++V+E C  G L+  L+  ++     +  L + D  +++  + + ++     GI HRD+KP NI+     D K         + K  DF    D  R  E     VS  C  + +      L   Y A  D WS+G TI+++  G CL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>4.16148e-07</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>660</Hsp_query-to>
      <Hsp_hit-from>38</Hsp_hit-from>
      <Hsp_hit-to>246</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>227</Hsp_align-len>
      <Hsp_qseq>TWSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQERESRVLAELDHPNIVRLLAVEEESVTRHRV---VVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLRE-KGIVHRDLKPGNIMRAFRADGKA-TYKLTDFDTARWLEDGEQFVSLCGTEEYLPRA---------YHATVDLWSIGVTIYHVATGCLPWAQLQELLSGLTGV</Hsp_qseq>
      <Hsp_hseq>SFPTTEVVGHGSFGVVFATVIQETNEKVAIKKVLQDK-----RFKNRELEIMKMLSHINIIDLKYFFYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLL----VDPETWSLKLCDFGSAKQLKPTEPNVSYICSRYY--RAPELIFGATNYTNQIDIWSSGCVMAELLLG-------QPMFPGESGI</Hsp_hseq>
      <Hsp_midline>++  T+V+G GS G V+    + T    AIK +  D        + RE  ++  L H NI+ L     E  ++  +   +++E         + +       +S  +    +  +   +N+L     + HRD+KP N++     D +  + KL DF +A+ L+  E  VS   +  Y  RA         Y   +D+WS G  +  +  G       Q +  G +G+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>4.33745e-07</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>474</Hsp_query-to>
      <Hsp_hit-from>357</Hsp_hit-from>
      <Hsp_hit-to>494</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>147</Hsp_align-len>
      <Hsp_qseq>VLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQ--ERESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDF</Hsp_qseq>
      <Hsp_hseq>VIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDA--QYLYLIMEFLPGGDLMTMLIRWQ---LFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNIL----IDIRGHIKLSDF</Hsp_hseq>
      <Hsp_midline>V+G+G+ G V   + + TG   A+K L    M +  +L   + E  VLA  D P +V L    +++  ++  ++ME   GG L ++L   +     +ED     +++ +  +  + + G +HRD+KP NI+     D +   KL+DF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YJL165C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:106894:109461:-1 gene:YJL165C transcript:YJL165C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HAL5 description:Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters; HAL5 has a paralog, KKQ8, that arose from the whole genome duplication [Source:SGD;Acc:S000003701]</Hit_def>
  <Hit_accession>YJL165C</Hit_accession>
  <Hit_len>855</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>4.86147e-07</Hsp_evalue>
      <Hsp_query-from>184</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>598</Hsp_hit-from>
      <Hsp_hit-to>769</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>52</Hsp_gaps>
      <Hsp_align-len>185</Hsp_align-len>
      <Hsp_qseq>LDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSIL------NEPENA----------------YGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDG-EQFVSL----CGTE------------EYLPRAYHATVDLWSIGVTIYHVATGCLPW</Hsp_qseq>
      <Hsp_hseq>FNAPNILKILDLMEYSNSF--VEVMEFCASGDLYSLLTRNNISNESNNGSSRLIQTVKEGSGSPLHPLEADCFMKQL---LNGVQYMHDHGIAHCDLKPENIL--FQPNG--LLKICDFGTSSVFQTAWEKHVHFQSGAMGSEPYVAPEEFIRDAEYDPR----LVDCWSCGIVYCTMVMGQYLW</Hsp_hseq>
      <Hsp_midline> + PNI+++L + E S +   V VME C+ G L+S+L      NE  N                 + L  D F++ L   + G+ ++ + GI H DLKP NI+  F+ +G    K+ DF T+   +   E+ V       G+E            EY PR     VD WS G+    +  G   W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>5.01038e-07</Hsp_evalue>
      <Hsp_query-from>43</Hsp_query-from>
      <Hsp_query-to>639</Hsp_query-to>
      <Hsp_hit-from>17</Hsp_hit-from>
      <Hsp_hit-to>236</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>232</Hsp_align-len>
      <Hsp_qseq>LGRGSTGCVYHG-RHRTTGAPSAIKVLSVDGMRRPPE-----LQERESRVLAELDHPNIVRLLAV--EEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQ-VLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDF------------DTARW------LEDGEQFVSLCGTEEYLPRA---YHA---TVDLWSIGVTIYHVATGCLPWAQLQEL</Hsp_qseq>
      <Hsp_hseq>LGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQKHHAGIIKLYYTFHDEENL----YFVLDFAPGGELLSLLHK----MGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVL--LDRDGRLM--ITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPFRGENEL</Hsp_hseq>
      <Hsp_midline>LG GS   V+     ++     AIKV S   + +  +     +++    +LA+  H  I++L     +EE++      V++   GG L S+L++     G   D + +   + ++  +  +   GI+HRDLKP N++     DG+    +TDF            D+A++       +D +   S  GT EY+      Y+      D+W++G  IY    G  P+    EL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>5.83709e-07</Hsp_evalue>
      <Hsp_query-from>190</Hsp_query-from>
      <Hsp_query-to>624</Hsp_query-to>
      <Hsp_hit-from>144</Hsp_hit-from>
      <Hsp_hit-to>290</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>HPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGEQFVSLCGTEEYL-PRAYH--------------ATVDLWSIGVTIYHVATGCLPWA</Hsp_qseq>
      <Hsp_hseq>HQNIAALLDFFDS------YIIMEYCSGGDLYEAIKA--DAVPKKTKSITHIITQIMDAIEYVHNKGIYHRDIKPENIL---ISGIDWTIKLTDWGLA--TTDKTSMDRNVGSERYMSPELFDSNLDIKERKEPYDCAKVDLWAMGIVFLNIVFHKNPFS</Hsp_hseq>
      <Hsp_midline>H NI  LL   +        ++ME CSGG L+  +    +A          +++ ++  + ++  KGI HRD+KP NI+    +    T KLTD+  A    D        G+E Y+ P  +               A VDLW++G+   ++     P++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>71</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>8.3408e-07</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>591</Hsp_query-to>
      <Hsp_hit-from>38</Hsp_hit-from>
      <Hsp_hit-to>240</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>218</Hsp_align-len>
      <Hsp_qseq>WSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQERESRVLAELD----HPNIVRLLAVEEESVTRHRVV-----VMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRA--------------------FRADGKATYKLTDFDTARWLEDGEQFVSLCGTEEYLPRAYHATVDLWSIGVTI</Hsp_qseq>
      <Hsp_hseq>YEIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGHKNIVNLIDLEIVTSSPYDGLYCYQELIDYDLAKVIHS-------SVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLS--------NQPYSKSVDIWAVGCIL</Hsp_hseq>
      <Hsp_midline>+ +   LG+G+ G V   + +     + I V  +  +     L +R  R L  ++    H NIV L+ +E  + + +  +     +++      +HS       +  LSE      L  ++ G+ ++    ++HRDLKPGNI+                      F+        +T++   RW    E  +S         + Y  +VD+W++G  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>72</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>8.93728e-07</Hsp_evalue>
      <Hsp_query-from>43</Hsp_query-from>
      <Hsp_query-to>609</Hsp_query-to>
      <Hsp_hit-from>29</Hsp_hit-from>
      <Hsp_hit-to>213</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>198</Hsp_align-len>
      <Hsp_qseq>LGRGSTGCVYHGRHRTTGAPSAIK-VLSVDGMRRPPELQERESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQ-VLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDFDTARWLEDGEQFVSLCGTEEYLP-------RAYHATVDLWSIGVTIYHVATG</Hsp_qseq>
      <Hsp_hseq>VGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLSPL--EDIYFVTELQGTDLHRLLQTRP-----LEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCD----LKICDFGLAR-IQD-PQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEG</Hsp_hseq>
      <Hsp_midline>+G G+ G V       T  P AIK ++         +   RE ++L  L H N++ L  +    +    +  +    G  LH +L          E  F+Q  L  ++ G+ ++   G++HRDLKP NI+     D     K+ DF  AR ++D  Q      T  Y         + Y   VD+WS G     +  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>73</Hit_num>
  <Hit_id>YHR135C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:372694:374310:-1 gene:YHR135C transcript:YHR135C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YCK1 description:Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform; shares redundant functions with Yck2p in morphogenesis, proper septin assembly, endocytic trafficking, and glucose sensing; stabilized by Sod1p binding in the presence of glucose and oxygen, causing glucose repression of respiratory metabolism; involved in the phosphorylation and regulation of glucose sensor Rgt2p; YCK1 has a paralog, YCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001177]</Hit_def>
  <Hit_accession>YHR135C</Hit_accession>
  <Hit_len>538</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>1.59002e-06</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>633</Hsp_query-to>
      <Hsp_hit-from>69</Hsp_hit-from>
      <Hsp_hit-to>279</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>219</Hsp_align-len>
      <Hsp_qseq>WSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQERESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIM--RAFRADGKATYKLTDFDTARWLEDGE--------QFVSLCGTEEY------LPRAYHATVDLWSIGVTIYHVATGCLPWAQLQ</Hsp_qseq>
      <Hsp_hseq>YKIGKKIGEGSFGVLFEGTNMINGVPVAIKFEPRK--TEAPQLRDEYKTYKILNGTPNIPYAYYFGQEGL--HNILVIDLL-GPSLEDLFDWCGRKFSVKT--VVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANNIH-LIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGHLPWQGLK</Hsp_hseq>
      <Hsp_midline>+ +   +G GS G ++ G +   G P AIK          P+L++           PNI       +E +  H ++V+++  G SL  + +     + +     +QV   ++  +  L    +++RD+KP N +  R  + D    + L DF  A+   D +        +  SL GT  Y      L R      D+ ++G   ++   G LPW  L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>74</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>1.76166e-06</Hsp_evalue>
      <Hsp_query-from>343</Hsp_query-from>
      <Hsp_query-to>582</Hsp_query-to>
      <Hsp_hit-from>173</Hsp_hit-from>
      <Hsp_hit-to>272</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>43</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>100</Hsp_align-len>
      <Hsp_qseq>VLSDVVAGMNHLREKGIVHRDLKPGNI-------------MRAFRADGKATYKLTDFDTARWLEDGEQFVSLCGTE-----EYLPRA--YHATVDLWSIG</Hsp_qseq>
      <Hsp_hseq>ILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVENKNPYTAYVSTRWYRSPEILLRSGYYSKPLDIWAFG</Hsp_hseq>
      <Hsp_midline>+LS ++AG+ H+ E    HRDLKP NI             M           KL DF  AR +E+   + +   T      E L R+  Y   +D+W+ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>75</Hit_num>
  <Hit_id>YNL154C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:343636:345276:-1 gene:YNL154C transcript:YNL154C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YCK2 description:Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform; shares redundant functions with Yck1p in morphogenesis, proper septin assembly, endocytic trafficking, and glucose sensing; stabilized by Sod1p binding in the presence of glucose and oxygen, causing glucose repression of respiratory metabolism; involved in the phosphorylation and regulation of glucose sensor Rgt2p; YCK2 has a paralog, YCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005098]</Hit_def>
  <Hit_accession>YNL154C</Hit_accession>
  <Hit_len>546</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>2.67539e-06</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>633</Hsp_query-to>
      <Hsp_hit-from>76</Hsp_hit-from>
      <Hsp_hit-to>286</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>221</Hsp_align-len>
      <Hsp_qseq>WSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQE--RESRVLAELDHPNIVRLLAVEEESVTRHRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIM--RAFRADGKATYKLTDFDTARWLEDGE--------QFVSLCGTEEY------LPRAYHATVDLWSIGVTIYHVATGCLPWAQLQ</Hsp_qseq>
      <Hsp_hseq>YKIGKKIGEGSFGVLFEGTNMINGLPVAIKFEPRK--TEAPQLKDEYRTYKILAGT--PGIPQEYYFGQEGL--HNILVIDLL-GPSLEDLFDWCGRRFSVKT--VVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANKVH-LIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEAMGHVFFYFLRGQLPWQGLK</Hsp_hseq>
      <Hsp_midline>+ +   +G GS G ++ G +   G P AIK          P+L++  R  ++LA    P I +     +E +  H ++V+++  G SL  + +     + +     +QV   ++  +  L    +++RD+KP N +  R  + D    + L DF  A+   D +        +  SL GT  Y      L R      D+ ++G   ++   G LPW  L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>76</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.2098</Hsp_bit-score>
      <Hsp_score>108</Hsp_score>
      <Hsp_evalue>8.29463e-06</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>609</Hsp_query-to>
      <Hsp_hit-from>363</Hsp_hit-from>
      <Hsp_hit-to>566</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>212</Hsp_align-len>
      <Hsp_qseq>LSENFTWSLTDVLGRGSTGCVYHGRHRTTGAPSAIKVLSVDGMRRPPELQER--ESRVL----AELDHPNIVRLLAVEEESVTR-HRVVVMEVCSGGSLHSILNEPENAYGLSEDDFLQVLSDVVAGMNHLREKGIVHRDLKPGNIMRAFRADGKATYKLTDF----DTARWLEDGEQFVSLCGTEEYLPRAYHATVDLWSIGVTIYHVATG</Hsp_qseq>
      <Hsp_hseq>VEQNRKYLVLDILGQGTFGQVVKCQNLLTKEILAVKVVK----SRTEYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKNHLCLVFELLSN-NLYELLKQ-NKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLC--APDKPELKIIDFGSSCEEARTVYTYIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAELFLG</Hsp_hseq>
      <Hsp_midline>+ +N  + + D+LG+G+ G V   ++  T    A+KV+      R   L +   E+++L     ++D  N    L + +  V + H  +V E+ S  +L+ +L +    +GLS        + ++  +  L+E  ++H DLKP NI+    A  K   K+ DF    + AR +    Q       E  L   Y  ++D+WS+G  +  +  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>93</Statistics_hsp-len>
      <Statistics_eff-space>837297188</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0028844-RA transcript Note:&quot;Protein of unknown function&quot; offset:340 AED:1.00 eAED:1.00 QI:340|0|0|0|0|0|3|1|94</Iteration_query-def>
  <Iteration_query-len>623</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>85</Statistics_hsp-len>
      <Statistics_eff-space>287074174</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058604-RA transcript Note:&quot;Similar to Rassf1 Ras association domain-containing protein 1 (Mus musculus)&quot; offset:0 AED:0.24 eAED:0.32 QI:0|0|0|0.6|1|1|5|0|270</Iteration_query-def>
  <Iteration_query-len>813</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>88</Statistics_hsp-len>
      <Statistics_eff-space>426987861</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058605-RA transcript Note:&quot;Similar to CFAP57 Cilia- and flagella-associated protein 57 (Homo sapiens)&quot; offset:0 AED:0.47 eAED:0.55 QI:0|0|0|1|1|1|3|0|318</Iteration_query-def>
  <Iteration_query-len>957</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>531295343</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058606-RA transcript Note:&quot;Similar to Cfap57 Cilia- and flagella-associated protein 57 (Mus musculus)&quot; offset:0 AED:0.16 eAED:0.16 QI:0|0.2|0.18|1|1|1|16|1062|784</Iteration_query-def>
  <Iteration_query-len>3417</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2341975613</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058609-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.34 eAED:0.58 QI:0|-1|0|1|-1|1|1|0|486</Iteration_query-def>
  <Iteration_query-len>1461</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>901411131</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058613-RA transcript Note:&quot;Protein of unknown function&quot; offset:187 AED:0.42 eAED:0.62 QI:187|0.2|0.33|1|0.6|0.5|6|0|164</Iteration_query-def>
  <Iteration_query-len>682</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>86</Statistics_hsp-len>
      <Statistics_eff-space>330851847</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0010300-RA transcript Note:&quot;Similar to C3orf84 Uncharacterized protein C3orf84 (Homo sapiens)&quot; offset:215 AED:0.01 eAED:0.01 QI:215|0.75|0.4|1|0.5|0.6|5|466|258</Iteration_query-def>
  <Iteration_query-len>1458</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>93</Statistics_hsp-len>
      <Statistics_eff-space>904004931</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058615-RA transcript Note:&quot;Similar to Pxk PX domain-containing protein kinase-like protein (Rattus norvegicus)&quot; offset:821 AED:0.26 eAED:0.30 QI:821|0.3|0.54|0.90|0.9|0.90|11|0|379</Iteration_query-def>
  <Iteration_query-len>1961</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1270220119</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058618-RA transcript Note:&quot;Similar to AHCYL2 Adenosylhomocysteinase 3 (Bos taurus)&quot; offset:69 AED:0.45 eAED:0.45 QI:69|0.71|0.87|1|1|1|8|0|261</Iteration_query-def>
  <Iteration_query-len>855</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YER043C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:235770:237119:-1 gene:YER043C transcript:YER043C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAH1 description:S-adenosyl-L-homocysteine hydrolase; catabolizes S-adenosyl-L-homocysteine which is formed after donation of the activated methyl group of S-adenosyl-L-methionine (AdoMet) to an acceptor; regulates cellular lipid homoeostasis by regulating phosphatidylcholine(PC)synthesis and triacylglycerol (TG) levels [Source:SGD;Acc:S000000845]</Hit_def>
  <Hit_accession>YER043C</Hit_accession>
  <Hit_len>449</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>94.7449</Hsp_bit-score>
      <Hsp_score>234</Hsp_score>
      <Hsp_evalue>1.55383e-22</Hsp_evalue>
      <Hsp_query-from>373</Hsp_query-from>
      <Hsp_query-to>807</Hsp_query-to>
      <Hsp_hit-from>273</Hsp_hit-from>
      <Hsp_hit-to>448</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>176</Hsp_align-len>
      <Hsp_qseq>EIEIAEQGNKNVVTREHLDRLKNGCIVCNMGHSNTEIDVASLRTPDLTWERVRSQVDHIIWPDGKRILLLAEGRLLNLSCSSV-PSFVLSITATTQALALIELYNAPE-------------GRYKQDVYLLPKKME-----------------LTDEQAKYLGINKNGPFKPNYYR</Hsp_qseq>
      <Hsp_hseq>QVFVTTTGCRDIINGEHFINMPEDAIVCNIGHFDIEIDVAWLKANAKECINIKPQVDRYLLSSGRHVILLANGRLVNLGCATGHSSFVMSCSFSNQVLAQIALFKSNDKSFREKHIEFQKTGPFEVGVHVLPKILDEAVAKFHLGNLGVRLTKLSKVQSEYLGIPEEGPFKADHYR</Hsp_hseq>
      <Hsp_midline>++ +   G ++++  EH   +    IVCN+GH + EIDVA L+        ++ QVD  +   G+ ++LLA GRL+NL C++   SFV+S + + Q LA I L+ + +             G ++  V++LPK ++                 L+  Q++YLGI + GPFK ++YR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>89</Statistics_hsp-len>
      <Statistics_eff-space>456026732</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0021472-RA transcript Note:&quot;Similar to MAGI1 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (Homo sapiens)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.47|0.38|18|0|1154</Iteration_query-def>
  <Iteration_query-len>3465</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2378040685</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058621-RA transcript Note:&quot;Similar to MON1A Vacuolar fusion protein MON1 homolog A (Macaca fascicularis)&quot; offset:0 AED:0.10 eAED:0.10 QI:0|0.36|0.25|0.66|1|1|12|4112|879</Iteration_query-def>
  <Iteration_query-len>6752</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YGL124C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:274780:276714:-1 gene:YGL124C transcript:YGL124C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MON1 description:Subunit of a heterodimeric guanine nucleotide exchange factor (GEF); subunit of the Mon1-Ccz1 GEF complex which stimulates nucleotide exchange and activation of Ypt7p, a Rab family GTPase involved in membrane tethering and fusion events at the late endosome and vacuole; GEF activity is stimulated by membrane association and anionic phospholipids; role in localizing Ypt7p to the vacuolar membrane; required for autophagy, the CVT pathway and mitophagy; potential Cdc28 substrate [Source:SGD;Acc:S000003092]</Hit_def>
  <Hit_accession>YGL124C</Hit_accession>
  <Hit_len>644</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>134.42</Hsp_bit-score>
      <Hsp_score>337</Hsp_score>
      <Hsp_evalue>1.87078e-32</Hsp_evalue>
      <Hsp_query-from>1501</Hsp_query-from>
      <Hsp_query-to>2619</Hsp_query-to>
      <Hsp_hit-from>182</Hsp_hit-from>
      <Hsp_hit-to>638</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>119</Hsp_identity>
      <Hsp_positive>210</Hsp_positive>
      <Hsp_gaps>90</Hsp_gaps>
      <Hsp_align-len>460</Hsp_align-len>
      <Hsp_qseq>KHIFVLSEAGKPIYSRHGSEEALSSIMGVMLALVSFVQASR-NAIRSIHTGT--HVVVFLQRGPLVLVAVSRSRQSEQQLAQELQYVYSQILSVLTATQLNRVFQTKQSYDLRRLLAGTE-RFLDSLLDLM--ETDPCFLLSAVRCLPLPGS----LRDSVSQSLQQAKD---KDLVFSVILA-----------KNHLVGTSHFGVQHGSRAECVPSICVEGEVWLPICLPQFNPSGFFYAHVSY----XXXXXXXXXXXXXXXREAFFTASDCRRRALERMRRQDALSGVLAALGSDSYSVAQTGIPDLRHFMYKCRSTSQFT--------------------RQRLFDLYQQLHGRVHNASRPL---KLIYHVR-------------------------------QQETL----LAWVTSGFELYTCFSP-LVTKAAAINAITKLLRWIKKEEERLFI</Hsp_qseq>
      <Hsp_hseq>KNFFIFTSAGKPIYCMHGKDEQIMSYTGLVNTVISYFQVNGPSELKTISTLTSGKRLTFLDKSPILLMAQSERGESSNELLNQLDFLYSYILSSLSERQLLRLFSKRENFDLRNYLESTDFENLDEICSLICNRMFPDLLLNSLQCLPFNHSSRLKLQNVVLQQLEKRQDIPRGTLLYGLIIAPQNKLCCVLRPRGHTLHTTDLHLLFCLISHQFQNLDETQELWVPICFPKFNSSGFLYCYIKFLPNDTHSNEKSALVLISAQKDAFFSLKSFSDELIIKLEEEKLLKKINTSKG---FKLSDIPAPMVHHFIYKSKQNVQYVMPHFEVNSNIALDSSQGLEYELKLKTYYQQLHGTVVRDNGNLLSRSMLNFVRWSSKDNEDLAMDETQMDFSELDEYIIGNSSFKQESVNMVGMAWVTPTFELYLIGNNGIVDKRVLFKSARKVANWCQKHESRLFI</Hsp_hseq>
      <Hsp_midline>K+ F+ + AGKPIY  HG +E + S  G++  ++S+ Q +  + +++I T T    + FL + P++L+A S   +S  +L  +L ++YS ILS L+  QL R+F  ++++DLR  L  T+   LD +  L+     P  LL++++CLP   S    L++ V Q L++ +D     L++ +I+A           + H + T+   +     +    ++    E+W+PIC P+FN SGF Y ++ +            L+L+ A ++AFF+        + ++  +  L  +  + G   + ++    P + HF+YK +   Q+                       +L   YQQLHG V   +  L    ++  VR                               +QE++    +AWVT  FELY   +  +V K     +  K+  W +K E RLFI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>105</Statistics_hsp-len>
      <Statistics_eff-space>4764188715</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0034763-RA transcript Note:&quot;Similar to CFTR Cystic fibrosis transmembrane conductance regulator (Squalus acanthias)&quot; offset:0 AED:0.84 eAED:1.00 QI:0|0|0|0.06|0.42|0.46|15|232|488</Iteration_query-def>
  <Iteration_query-len>1699</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDR135C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:723004:727551:-1 gene:YDR135C transcript:YDR135C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YCF1 description:Vacuolar glutathione S-conjugate transporter; ABC-C transporter of the ATP-binding cassette family; required for vacuole fusion; forms stable complexes with vacuole fusion machinery; regulates Vam7p recruitment to vacuoles; role in detoxifying metals (Cd, Hg, As); transports GSSG that is not immediately reduced in cytosol to vacuole; transports unconjugated bilirubin, selenodigluthatione, oxidized glutathione; similar to human cystic fibrosis protein CFTR [Source:SGD;Acc:S000002542]</Hit_def>
  <Hit_accession>YDR135C</Hit_accession>
  <Hit_len>1515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>4.46573e-08</Hsp_evalue>
      <Hsp_query-from>313</Hsp_query-from>
      <Hsp_query-to>1344</Hsp_query-to>
      <Hsp_hit-from>261</Hsp_hit-from>
      <Hsp_hit-to>673</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>110</Hsp_identity>
      <Hsp_positive>171</Hsp_positive>
      <Hsp_gaps>159</Hsp_gaps>
      <Hsp_align-len>458</Hsp_align-len>
      <Hsp_qseq>REWDREISQSENRPHLLTAIRRCFLWRFVGLGVIMLLAEFTKVV-------QPFFLG---QIIASFN-----------------PSTVDVQEPLLLALGLSACFVVRTLLLHPAVFGLQHLGMDVRIATFCLIYKK----------------IMKLSSSVLDK-------------------ITVGQLVSLLSNN-------------LNKF----------------DERIALTSEVLENIEAIKVHGWEEAMGKLIDELR-KQELK-LTSRASYSRYXXXXXXXXXXXXXXXXXILPYA---------VYNE---LTLRRVLTSVSFFNVLRMAITRSLPWSLQMWVDATASIRKIQDFLLLKEYRPLDYNLSTTEVEIVSITASWDQIDGIVPEQGSKVKN---GIINVA--ATDL----PFYKSYVLSDINFKLNKGEMLIVMGSFGSGKNITL</Hsp_qseq>
      <Hsp_hseq>KNWENELKQKSN-PSLSWAICRTF-------GSKMLLAAFFKAIHDVLAFTQPQLLRILIKFVTDYNSERQDDHSSLQGFENNHPQKLPIVRGFLIAFAMFLVGFTQTSVLHQYFLNVFNTGMYIKSALTALIYQKSLVLSNEASGLSSTGDIVNLMSVDVQKLQDLTQWLNLIWSGPFQIIICLYSLYKLLGNSMWVGVIILVIMMPLNSFLMRIQKKLQKSQMKYKDERTRVISEILNNIKSLKLYAWEKPYREKLEEVRNNKELKNLTKLGCY-----------MAVTSFQFNIVPFLVSCCTFAVFVYTEDRALTTDLVFPALTLFNLLSFPLM-IIPMVLNSFIEASVSIGRLFTFFTNEELQP----------------------DSV--QRLPKVKNIGDVAINIGDDATFLWQRKPEYK-VALKNINFQAKKGNLTCIVGKVGSGKTALL</Hsp_hseq>
      <Hsp_midline>+ W+ E+ Q  N P L  AI R F       G  MLLA F K +       QP  L    + +  +N                 P  + +    L+A  +      +T +LH     + + GM ++ A   LIY+K                I+ L S  + K                   I +  L  LL N+             LN F                DER  + SE+L NI+++K++ WE+   + ++E+R  +ELK LT    Y             V     +I+P+          VY E   LT   V  +++ FN+L   +   +P  L  +++A+ SI ++  F   +E +P                      D +  ++  KVKN     IN+   AT L    P YK   L +INF+  KG +  ++G  GSGK   L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YHL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:27978:32756:-1 gene:YHL035C transcript:YHL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VMR1 description:Vacuolar membrane protein; involved in multiple drug resistance and metal sensitivity; ATP-binding cassette (ABC) family member involved in drug transport; potential Cdc28p substrate; induced under respiratory conditions; VMR1 has a paralog, YBT1, that arose from the whole genome duplication [Source:SGD;Acc:S000001027]</Hit_def>
  <Hit_accession>YHL035C</Hit_accession>
  <Hit_len>1592</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>7.64605e-08</Hsp_evalue>
      <Hsp_query-from>697</Hsp_query-from>
      <Hsp_query-to>1335</Hsp_query-to>
      <Hsp_hit-from>507</Hsp_hit-from>
      <Hsp_hit-to>709</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>226</Hsp_align-len>
      <Hsp_qseq>LLSNNLNKF--------DERIALTSEVLENIEAIKVHGWEEAMGKLIDELRKQELKLTSRAS--YSRYXXXXXXXXXXXXXXXXXILPYAVYNELTLRRVLTSVSFFNVLRMAITRSLPWSLQMWVDATASIRKIQDFLLLKE---YRPLDYNLSTTEVEIVSITASWDQIDGIVPEQGSKVKNGIINVAATDLPFYKSYVLSDINFKLNKGEMLIVMGSFGSGKN</Hsp_qseq>
      <Hsp_hseq>LLANLLGKFQKQTLKCTDQRISKLNECLQNIRIVKYFAWERNIINEIKSIRQKELRSLLKKSLVWSVTSFLWFVTPTLVTGVTFAICTFVQHEDLNAPLAFTTLSLFTLLKTPLDQ-LSNMLSFINQSKVSLKRISDFLRMDDTEKYNQLTISPDKNKIEFKNATLTWNEND-------------------SDMNAFK---LCGLNIKFQIGKLNLILGSTGSGKS</Hsp_hseq>
      <Hsp_midline>LL+N L KF        D+RI+  +E L+NI  +K   WE  +   I  +R++EL+   + S  +S          + V  V  +I  +  + +L      T++S F +L+  + + L   L     +  S+++I DFL + +   Y  L  +    ++E  + T +W++ D                   +D+  +K   L  +N K   G++ +++GS GSGK+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YLL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:41280:46265:-1 gene:YLL048C transcript:YLL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YBT1 description:Transporter of the ATP-binding cassette (ABC) family; involved in bile acid transport; negative regulator of vacuole fusion; regulates release of lumenal Ca2+ stores; similar to mammalian bile transporters; YBT1 has a paralog, VMR1, that arose from the whole genome duplication [Source:SGD;Acc:S000003971]</Hit_def>
  <Hit_accession>YLL048C</Hit_accession>
  <Hit_len>1661</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>5.21712e-07</Hsp_evalue>
      <Hsp_query-from>697</Hsp_query-from>
      <Hsp_query-to>1332</Hsp_query-to>
      <Hsp_hit-from>545</Hsp_hit-from>
      <Hsp_hit-to>735</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>218</Hsp_align-len>
      <Hsp_qseq>LLSNNLNKFDERIALTSEVLENIEAIKVHGWEEAMGKLIDELRKQELKLTSRASYSRYXXXXXXXXXXXXXXXXXILPYAVYNE---LTLRRVLTSVSFFNVLRMAITRSLPWSLQMWVDATASIRKIQDFLL---LKEYRPLDYNLSTTEVEIVSITASWDQIDGIVPEQGSKVKNGIINVAATDLPFYKSYVLSDINFKLNKGEMLIVMGSFGSGK</Hsp_qseq>
      <Hsp_hseq>LQKKNLAVTDNRIQKLNEAFQAIRIIKYFSWEENFEKDINTIRENELSLLLMRSIV-WSISSFLWFVTPTIVTAASFAYYIYVQGEVLTTPVAFTALSLFTLLRDPLDR-LSDMLSFVVQSKVSLDRVQDFLNENDTKKYDQLTIDPNGNRFAFENSTISWDKDN-------------------------QDFKLKDLNIEFKTGKLNVVIGPTGSGK</Hsp_hseq>
      <Hsp_midline>L   NL   D RI   +E  + I  IK   WEE   K I+ +R+ EL L    S   +  S+  +F    +V A+   Y +Y +   LT     T++S F +LR  + R L   L   V +  S+ ++QDFL     K+Y  L  + +       + T SWD+ +                         + + L D+N +   G++ +V+G  GSGK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YLL015W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:116432:121111:1 gene:YLL015W transcript:YLL015W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BPT1 description:ABC type transmembrane transporter of MRP/CFTR family; found in vacuolar membrane, involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates, along with Ycf1p [Source:SGD;Acc:S000003938]</Hit_def>
  <Hit_accession>YLL015W</Hit_accession>
  <Hit_len>1559</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>8.63809e-07</Hsp_evalue>
      <Hsp_query-from>277</Hsp_query-from>
      <Hsp_query-to>705</Hsp_query-to>
      <Hsp_hit-from>253</Hsp_hit-from>
      <Hsp_hit-to>398</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>151</Hsp_align-len>
      <Hsp_qseq>PGECGVRSAGKAREWDREISQSENRPHLLTAIRRCFLWRFVG--LGVIMLL---AEFTKVVQPFFLGQIIASFNPSTVDVQEPL---LLALGLSACFVVRTLLLHPAVFGLQHLGMDVRIATFCLIYKKIMKLSSSVLDKITVGQLVSLLS</Hsp_qseq>
      <Hsp_hseq>PVDLNIKSISKEFKANWELEKWLNRNSLWRAI-----WKSFGRTISVAMLYETTSDLLSVVQPQFLRIFIDGLNPETSSKYPPLNGVFIALTLFVISVVSVFLTNQFYIGIFEAGLGIRGSLASLVYQKSLRLTLAERNEKSTGDILNLMS</Hsp_hseq>
      <Hsp_midline>P +  ++S  K  + + E+ +  NR  L  AI     W+  G  + V ML    ++   VVQP FL   I   NP T     PL    +AL L    VV   L +    G+   G+ +R +   L+Y+K ++L+ +  ++ + G +++L+S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1077208557</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058623-RA transcript Note:&quot;Similar to Cyp2g1 Cytochrome P450 2G1 (Rattus norvegicus)&quot; offset:0 AED:0.32 eAED:0.51 QI:0|0.14|0|1|1|1|8|0|393</Iteration_query-def>
  <Iteration_query-len>1182</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>92</Statistics_hsp-len>
      <Statistics_eff-space>696673834</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0045198-RA transcript Note:&quot;Similar to SLC16A7 Monocarboxylate transporter 2 (Homo sapiens)&quot; offset:228 AED:0.22 eAED:0.22 QI:228|0|0|0.85|0.66|0.71|7|146|460</Iteration_query-def>
  <Iteration_query-len>1757</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1120662830</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0027686-RA transcript Note:&quot;Similar to Dnajc16 DnaJ homolog subfamily C member 16 (Mus musculus)&quot; offset:0 AED:0.39 eAED:0.39 QI:0|0.46|0.35|1|0.53|0.64|14|657|637</Iteration_query-def>
  <Iteration_query-len>2571</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1720855653</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

