<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0045667-RA transcript Note:&quot;Similar to etfrf1 Electron transfer flavoprotein regulatory factor 1 (Taeniopygia guttata)&quot; offset:2 AED:0.23 eAED:0.23 QI:2|0|0|0.66|0.5|0.33|3|0|154</BlastOutput_query-def>
  <BlastOutput_query-len>467</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0045667-RA transcript Note:&quot;Similar to etfrf1 Electron transfer flavoprotein regulatory factor 1 (Taeniopygia guttata)&quot; offset:2 AED:0.23 eAED:0.23 QI:2|0|0|0.66|0.5|0.33|3|0|154</Iteration_query-def>
  <Iteration_query-len>467</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>82</Statistics_hsp-len>
      <Statistics_eff-space>173219291</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061688-RA transcript Note:&quot;Similar to kcp Kielin/chordin-like protein (Xenopus laevis)&quot; offset:0 AED:0.42 eAED:0.43 QI:0|0.4|0.16|0.83|1|1|6|0|324</Iteration_query-def>
  <Iteration_query-len>975</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>545215745</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061690-RA transcript Note:&quot;Similar to melC2 Tyrosinase (Streptomyces antibioticus)&quot; offset:0 AED:0.93 eAED:0.93 QI:0|0|0|0.08|1|1|12|0|1532</Iteration_query-def>
  <Iteration_query-len>4599</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3195001810</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061691-RA transcript Note:&quot;Similar to IRF6 Interferon regulatory factor 6 (Bos taurus)&quot; offset:9 AED:0.30 eAED:0.37 QI:9|0.25|0.4|1|1|1|5|0|300</Iteration_query-def>
  <Iteration_query-len>912</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>89</Statistics_hsp-len>
      <Statistics_eff-space>500233405</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0027032-RA transcript Note:&quot;Similar to MUC5AC Mucin-5AC (Homo sapiens)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.18|0.30|23|1345|535</Iteration_query-def>
  <Iteration_query-len>2953</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>2000690295</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0030081-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.22|0.3|10|0|495</Iteration_query-def>
  <Iteration_query-len>1488</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>922054134</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061694-RA transcript Note:&quot;Similar to rps10 40S ribosomal protein S10 (Ictalurus punctatus)&quot; offset:0 AED:0.06 eAED:0.06 QI:0|0.8|0.83|1|0.6|0.66|6|1423|154</Iteration_query-def>
  <Iteration_query-len>1888</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YOR293W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:867098:867852:1 gene:YOR293W transcript:YOR293W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RPS10A description:Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S10, no bacterial homolog; RPS10A has a paralog, RPS10B, that arose from the whole genome duplication; mutations in the human homolog associated with Diamond-Blackfan anemia [Source:SGD;Acc:S000005819]</Hit_def>
  <Hit_accession>YOR293W</Hit_accession>
  <Hit_len>105</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>104.76</Hsp_bit-score>
      <Hsp_score>260</Hsp_score>
      <Hsp_evalue>2.16596e-27</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>285</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>102</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>103</Hsp_align-len>
      <Hsp_qseq>MLMPKKDRVAIYELLFKEGVMVAKKDVHLAKHPELAEKN--------SLKSRGFVKEQFAWRHFYWYLTNEGIQYLRDFLHLPPEIVPATLRRQIRPETARPR</Hsp_qseq>
      <Hsp_hseq>MLMPKEDRNKIHQYLFQEGVVVAKKDFNQAKHEEIDTKNLYVIKALQSLTSKGYVKTQFSWQYYYYTLTEEGVEYLREYLNLPEHIVPGTYIQERNP-TQRPQ</Hsp_hseq>
      <Hsp_midline>MLMPK+DR  I++ LF+EGV+VAKKD + AKH E+  KN        SL S+G+VK QF+W+++Y+ LT EG++YLR++L+LP  IVP T  ++  P T RP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YMR230W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:732414:733141:1 gene:YMR230W transcript:YMR230W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RPS10B description:Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S10, no bacterial homolog; RPS10B has a paralog, RPS10A, that arose from the whole genome duplication; mutations in the human homolog associated with Diamond-Blackfan anemia [Source:SGD;Acc:S000004843]</Hit_def>
  <Hit_accession>YMR230W</Hit_accession>
  <Hit_len>105</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>102.064</Hsp_bit-score>
      <Hsp_score>253</Hsp_score>
      <Hsp_evalue>1.83701e-26</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>285</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>102</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>103</Hsp_align-len>
      <Hsp_qseq>MLMPKKDRVAIYELLFKEGVMVAKKDVHLAKHPELAEKN--------SLKSRGFVKEQFAWRHFYWYLTNEGIQYLRDFLHLPPEIVPATLRRQIRPETARPR</Hsp_qseq>
      <Hsp_hseq>MLMPKQERNKIHQYLFQEGVVVAKKDFNQAKHEEIDTKNLYVIKALQSLTSKGYVKTQFSWQYYYYTLTEEGVEYLREYLNLPEHIVPGTYIQERNP-SQRPQ</Hsp_hseq>
      <Hsp_midline>MLMPK++R  I++ LF+EGV+VAKKD + AKH E+  KN        SL S+G+VK QF+W+++Y+ LT EG++YLR++L+LP  IVP T  ++  P + RP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1215488911</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061695-RA transcript Note:&quot;Similar to Etfbkmt Electron transfer flavoprotein beta subunit lysine methyltransferase (Rattus norvegicus)&quot; offset:0 AED:0.32 eAED:0.34 QI:0|-1|0|1|-1|1|1|0|92</Iteration_query-def>
  <Iteration_query-len>279</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>64</Statistics_hsp-len>
      <Statistics_eff-space>72258343</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061696-RA transcript Note:&quot;Similar to etfbkmt Electron transfer flavoprotein beta subunit lysine methyltransferase (Xenopus laevis)&quot; offset:0 AED:0.51 eAED:0.52 QI:0|0|0|0.66|1|1|3|0|136</Iteration_query-def>
  <Iteration_query-len>411</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>80</Statistics_hsp-len>
      <Statistics_eff-space>136005819</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0046437-RA transcript Note:&quot;Similar to Wee1 Wee1-like protein kinase (Rattus norvegicus)&quot; offset:1 AED:0.45 eAED:0.45 QI:1|0|0|0.37|0.33|0.25|16|200|896</Iteration_query-def>
  <Iteration_query-len>2892</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.4925</Hsp_bit-score>
      <Hsp_score>197</Hsp_score>
      <Hsp_evalue>3.63096e-16</Hsp_evalue>
      <Hsp_query-from>689</Hsp_query-from>
      <Hsp_query-to>1087</Hsp_query-to>
      <Hsp_hit-from>24</Hsp_hit-from>
      <Hsp_hit-to>154</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>135</Hsp_align-len>
      <Hsp_qseq>LGHGHFGSVSRCVKRLDGCVYAVKRSRRPVAHSADEQIAL--REVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIAQRTL</Hsp_qseq>
      <Hsp_hseq>IGRGNFGDVYKAVDRVTQEIVAIKVVN--LEHS-DEDIELLAQEIFFLAEL-KSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGM</Hsp_hseq>
      <Hsp_midline>+G G+FG V + V R+   + A+K     + HS DE I L  +E+   A L + P +  Y +   ED  M+I  EYC GGS +D L RS  +  PE +V  ++  V  GL+Y+H    +H DIK +NI + +  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.1814</Hsp_bit-score>
      <Hsp_score>191</Hsp_score>
      <Hsp_evalue>3.33867e-15</Hsp_evalue>
      <Hsp_query-from>668</Hsp_query-from>
      <Hsp_query-to>1399</Hsp_query-to>
      <Hsp_hit-from>443</Hsp_hit-from>
      <Hsp_hit-to>694</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>266</Hsp_align-len>
      <Hsp_qseq>EFHELGALGHGHFGSVSRCVKRLDGCVYAVKRSRRPVAHSADEQI-----ALREVCAHAVLGQH--PHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHA----FPEWRVRRMLLHVARGLRYIH-SLGLVHMDIKPSNIFIAQRTLSSELEEGE-------PQSDAGRVNSRHVEEGDSRFLALEVLQQ---DYLASPQXXXXXXXXXXXXXXXXXXXPRNEADWIRIRQGWLPEGAAVASLSLELRTLLTAMVRPQAGE</Hsp_qseq>
      <Hsp_hseq>KFTNVHSIGKGQFSTVYQVTFAQTNKKYAIK-AIKPNKYNSLKRILLEIKILNEVTNQITMDQEGKEYIIDYISSWKFQNSYYIMTELCENGNL-DGFLQEQVIAKKKRLEDWRIWKIIVELSLALRFIHDSCHIVHLDLKPANVMI---TFEGNLKLGDFGMATHLPLEDKSFEN-----EGDREYIAPEIISDCTYDYKAD----IFSLGLMIVEIAANVVLPDNGNAWHKLRSGDLSDAGRLSSTDIHSESLFSDITKVDTND</Hsp_hseq>
      <Hsp_midline>+F  + ++G G F +V +         YA+K + +P  +++ ++I      L EV     + Q    +++ Y S+W   N  YI  E C  G++ D  L+    A      +WR+ ++++ ++  LR+IH S  +VH+D+KP+N+ I   T    L+ G+       P  D    N     EGD  ++A E++     DY A     +F+L L  V  A    LP N   W ++R G L +   ++S  +   +L + + +    +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.7886</Hsp_bit-score>
      <Hsp_score>177</Hsp_score>
      <Hsp_evalue>1.83648e-13</Hsp_evalue>
      <Hsp_query-from>689</Hsp_query-from>
      <Hsp_query-to>1078</Hsp_query-to>
      <Hsp_hit-from>1181</Hsp_hit-from>
      <Hsp_hit-to>1313</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>135</Hsp_align-len>
      <Hsp_qseq>LGHGHFGSVSRCVKRLDGCVYAVKRSRRPVAHSADEQI-----ALREVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIAQ</Hsp_qseq>
      <Hsp_hseq>IGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLEYVAGGSV-GSLIRMYGR-FDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQ</Hsp_hseq>
      <Hsp_midline>+G G FG+V  C+    G + AVK+   P   S +E I     ALR   +      H ++VQY     ++N   +  EY +GGSV  +L+R  G  F E  ++ +   V +GL Y+HS G++H D+K  N+ + Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.3218</Hsp_bit-score>
      <Hsp_score>168</Hsp_score>
      <Hsp_evalue>1.82492e-12</Hsp_evalue>
      <Hsp_query-from>668</Hsp_query-from>
      <Hsp_query-to>1081</Hsp_query-to>
      <Hsp_hit-from>351</Hsp_hit-from>
      <Hsp_hit-to>486</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>141</Hsp_align-len>
      <Hsp_qseq>EFHELGALGHGHFGSVSRCVKRLDGCVYAVKRSRRPVAHSADEQI---ALREVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIAQR</Hsp_qseq>
      <Hsp_hseq>DFHTVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKAERDVLAGS---DSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIR--WQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIR</Hsp_hseq>
      <Hsp_midline>+FH +  +G G FG V    K+  G +YA+K   +   +  D+     A R+V A +     P VV  Y ++ +  ++Y+  E+  GG +   L+R     F E   R  +      +  IH LG +H DIKP NI I  R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>1.22873e-11</Hsp_evalue>
      <Hsp_query-from>686</Hsp_query-from>
      <Hsp_query-to>1078</Hsp_query-to>
      <Hsp_hit-from>203</Hsp_hit-from>
      <Hsp_hit-to>329</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>132</Hsp_align-len>
      <Hsp_qseq>ALGHGHFGSVSRCVKRLDGCVYAVKR-SRRPVAHSADEQIALREVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIAQ</Hsp_qseq>
      <Hsp_hseq>VVGQGAFATVKKAIERTTGKTFAVKIISKRKVIGNMDGVTRELEVLQKL---NHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFV--AAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQ</Hsp_hseq>
      <Hsp_midline> +G G F +V + ++R  G  +AVK  S+R V  + D      EV        HP +V+    + +    Y+  E+ SGG + D +  +   A  E   R +   +   ++YIHS+G+ H D+KP NI I Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>1.44371e-11</Hsp_evalue>
      <Hsp_query-from>689</Hsp_query-from>
      <Hsp_query-to>1072</Hsp_query-to>
      <Hsp_hit-from>1272</Hsp_hit-from>
      <Hsp_hit-to>1398</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>135</Hsp_align-len>
      <Hsp_qseq>LGHGHFGSVSRCVKRLDGCVYAVK-------RSRRPVAHSADEQIALREVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFI</Hsp_qseq>
      <Hsp_hseq>IGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEIL------NHPNIVSYYGVEVHRDKVNIFMEYCEGGSL--AALLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILL</Hsp_hseq>
      <Hsp_midline>+G G FG V   V   +G + AVK       +S + +     E++++ E+        HP++V YY      + + I  EYC GGS+  A L   G    E   +   L +  GL Y+H  G+VH D+KP NI +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>1.87452e-11</Hsp_evalue>
      <Hsp_query-from>671</Hsp_query-from>
      <Hsp_query-to>1078</Hsp_query-to>
      <Hsp_hit-from>496</Hsp_hit-from>
      <Hsp_hit-to>631</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>FHELGALGHGHFGSVSRCVKRLDGCVYAVKRSRRPVAHSADEQIA----LREVCAHAVLG--QHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIAQ</Hsp_qseq>
      <Hsp_hseq>FEKIRLLGQGDVGKVFLVREKKTNRVYALK------VLSKDEMIKRNKIKRVLTEQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQ</Hsp_hseq>
      <Hsp_midline>F ++  LG G  G V    ++    VYA+K        S DE I      R +    +L    HP +V  Y ++  ++++Y+  EYC GG    AL         E   R     V   L Y+H LG ++ D+KP NI + Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>3.24198e-11</Hsp_evalue>
      <Hsp_query-from>689</Hsp_query-from>
      <Hsp_query-to>1129</Hsp_query-to>
      <Hsp_hit-from>1040</Hsp_hit-from>
      <Hsp_hit-to>1185</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>148</Hsp_align-len>
      <Hsp_qseq>LGHGHFGSVSRCVKRLDGCVYAVKRSRRPVAHSADEQIAL-REVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIAQRTLSSELEEGEPQSDAG</Hsp_qseq>
      <Hsp_hseq>IGGGTFGQVYSAINLENGEILAVKEIKIHDTTTMKKIFPLIKEEMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEYCEGGSL--ASLLDHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDFNGIIKYVDFGTARTVVG</Hsp_hseq>
      <Hsp_midline>+G G FG V   +   +G + AVK  +     +  +   L +E      +  HP++VQYY      + + I  EYC GGS+  A L   G    E   +     +  GL Y+H  G+VH DIKP NI +    +   ++ G  ++  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>4.19883e-11</Hsp_evalue>
      <Hsp_query-from>671</Hsp_query-from>
      <Hsp_query-to>1078</Hsp_query-to>
      <Hsp_hit-from>324</Hsp_hit-from>
      <Hsp_hit-to>459</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>139</Hsp_align-len>
      <Hsp_qseq>FHELGALGHGHFGSVSRCVKRLDGCVYAVKRSRRPVAHSADEQIALREVCAHAVL---GQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIAQ</Hsp_qseq>
      <Hsp_hseq>FEKIRLLGQGDVGKVYLVRERDTNQIFALKVLNK---HEMIKRKKIKRVLTEQEILATSDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQ</Hsp_hseq>
      <Hsp_midline>F ++  LG G  G V    +R    ++A+K   +   H   ++  ++ V     +     HP +V  Y ++   +++Y+  EYC GG    AL         E   +     V   L Y+H LG ++ D+KP NI + Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>4.59287e-11</Hsp_evalue>
      <Hsp_query-from>662</Hsp_query-from>
      <Hsp_query-to>1081</Hsp_query-to>
      <Hsp_hit-from>20</Hsp_hit-from>
      <Hsp_hit-to>155</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>141</Hsp_align-len>
      <Hsp_qseq>STEFHELGALGHGHFGSVSRCVKRLDGCVYAVKRSRRPVAHSADE-QIALREVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIAQR</Hsp_qseq>
      <Hsp_hseq>SSLFKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLN--LDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLR-SLLR-PGK-IDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNE</Hsp_hseq>
      <Hsp_midline>S+ F     +G G FG V +      G VYA+K     +   +DE +   RE+   A L Q  ++ +YY ++ +D  ++I  E+C+GGS+  +LLR PG    E  +  ++  +   L+ IH   ++H DIK +N+ I   </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>5.21308e-11</Hsp_evalue>
      <Hsp_query-from>668</Hsp_query-from>
      <Hsp_query-to>1081</Hsp_query-to>
      <Hsp_hit-from>213</Hsp_hit-from>
      <Hsp_hit-to>353</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>EFHELGALGHGHFGSVSRCVKRLDGCVYAVKRSRRPVAHSADEQIALREVCAHAVLGQHPHVVQYYSAWAED--NHMYIQNEYCSGGSV--TDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIAQR</Hsp_qseq>
      <Hsp_hseq>EITTLGILGEGAGGSVAKCRLKNGKKVFALKTINTMNTDPEYQKQIFRELQFNKSF-KSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEK</Hsp_hseq>
      <Hsp_midline>E   LG LG G  GSV++C  +    V+A+K           ++   RE+  +    +  ++VQYY  + ++  + +YI  EY  G S+  T   L   G    E  + ++   V RGL Y+H   ++H DIKP NI + ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>5.32598e-11</Hsp_evalue>
      <Hsp_query-from>680</Hsp_query-from>
      <Hsp_query-to>1081</Hsp_query-to>
      <Hsp_hit-from>224</Hsp_hit-from>
      <Hsp_hit-to>360</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>139</Hsp_align-len>
      <Hsp_qseq>LGALGHGHFGSVSRCVKRLDGCVYAVKRSRRPVAHSADEQIALREVCAHAVLGQHPHVVQYYSAWAEDNH--MYIQNEYCSGGSVTDALLRSP---GHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIAQR</Hsp_qseq>
      <Hsp_hseq>LGILGEGAGGSVSKCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQFNRSF-QSEYIVRYYGMFTDDENSSIYIAMEYM-GGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNEN</Hsp_hseq>
      <Hsp_midline>LG LG G  GSVS+C  +    ++A+K           ++   RE+  +    Q  ++V+YY  + +D +  +YI  EY  GG   DA+ ++    G    E  + ++   V RGL Y+H   ++H DIKP NI + + </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>1.91498e-10</Hsp_evalue>
      <Hsp_query-from>662</Hsp_query-from>
      <Hsp_query-to>1075</Hsp_query-to>
      <Hsp_hit-from>22</Hsp_hit-from>
      <Hsp_hit-to>155</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>141</Hsp_align-len>
      <Hsp_qseq>STEFHELGALGHGHFGSVSRCVKRLDGCVYAVKRSRRPVAHSADEQIALREVCAHAVLGQ---HPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIA</Hsp_qseq>
      <Hsp_hseq>SVQYHLKQVIGRGSYGVVYKAINKHTDQVVAIKE----VVYENDEE--LNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRS-STGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLS</Hsp_hseq>
      <Hsp_midline>S ++H    +G G +G V + + +    V A+K     V +  DE+  L ++ A   L +   H ++V+Y+    +   +YI  EYC+ GS+   + RS      E   +  +     GL+Y+H  G++H DIK +NI ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>2.91632e-10</Hsp_evalue>
      <Hsp_query-from>686</Hsp_query-from>
      <Hsp_query-to>1072</Hsp_query-to>
      <Hsp_hit-from>26</Hsp_hit-from>
      <Hsp_hit-to>160</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>139</Hsp_align-len>
      <Hsp_qseq>ALGHGHFGSVSRCVKRLDGCVYAVKRSRRPV-----AHSADEQI----ALREVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHA-FPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFI</Hsp_qseq>
      <Hsp_hseq>TLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLS-HPNVLSLYDVWETNNNLYLILEYAEKGELFNLLV---DHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLL</Hsp_hseq>
      <Hsp_midline> LG G  G V        G   AVK   + +      HS D+ +      RE+    +L  HP+V+  Y  W  +N++Y+  EY   G + + L+    H   PE         +  G+ Y H+LG+VH D+KP N+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>3.15018e-10</Hsp_evalue>
      <Hsp_query-from>698</Hsp_query-from>
      <Hsp_query-to>1072</Hsp_query-to>
      <Hsp_hit-from>85</Hsp_hit-from>
      <Hsp_hit-to>212</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>131</Hsp_align-len>
      <Hsp_qseq>GHF---GSVSRCVKRLD--GCVYAVKR-SRRPVAHSADEQIALREVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFI</Hsp_qseq>
      <Hsp_hseq>GHFLGEGGFARCFQIKDDSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMS-HPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPE--VRFFTTQICGAIKYMHSRRVIHRDLKLGNIFF</Hsp_hseq>
      <Hsp_midline>GHF   G  +RC +  D  G ++A K  ++  +      +  L E+  H  +  HP++VQ+   + +D+++YI  E C  GS+ + L R      PE  VR     +   ++Y+HS  ++H D+K  NIF </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>5.7718e-10</Hsp_evalue>
      <Hsp_query-from>809</Hsp_query-from>
      <Hsp_query-to>1072</Hsp_query-to>
      <Hsp_hit-from>80</Hsp_hit-from>
      <Hsp_hit-to>164</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>89</Hsp_align-len>
      <Hsp_qseq>REVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALL-RSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFI</Hsp_qseq>
      <Hsp_hseq>REIIIMKLLN-HPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGP---LPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLL</Hsp_hseq>
      <Hsp_midline>RE+    +L  HP+V++ Y  W  +  +Y+  EY   G + + L+ R P    PE    R    +  G+ Y H+LG+VH D+KP N+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>8.34778e-10</Hsp_evalue>
      <Hsp_query-from>668</Hsp_query-from>
      <Hsp_query-to>1072</Hsp_query-to>
      <Hsp_hit-from>86</Hsp_hit-from>
      <Hsp_hit-to>218</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>EFHELGALGHGHFGSVSRCVKRLDGCVYAVKRSRRPVA-------HSADEQIALREVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFI</Hsp_qseq>
      <Hsp_hseq>DFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVT-------HPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKS--QRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILL</Hsp_hseq>
      <Hsp_midline>+F  L  LG G FG V     R +G  YA+K  ++ +        H+ DE++ L  V        HP +++ +  + +   +++  +Y  GG +   L +S    FP    +     V   L Y+HS  +++ D+KP NI +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>1.33207e-09</Hsp_evalue>
      <Hsp_query-from>668</Hsp_query-from>
      <Hsp_query-to>1069</Hsp_query-to>
      <Hsp_hit-from>359</Hsp_hit-from>
      <Hsp_hit-to>492</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>EFHELGALGHGHFGSVSRCVKRLDGCVYAVKRSRRPVAHSADEQIALREVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDAL--------LRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIF</Hsp_qseq>
      <Hsp_hseq>ELEFLDELGHGNYGNVSKVLHKPTNVIMATKEVRLELDEAKFRQILMELEVLHKC--NSPYIVDFYGAFFIEGAVYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAF----IANAVIHGLKELKEQHN--IIHRDVKPTNIL</Hsp_hseq>
      <Hsp_midline>E   L  LGHG++G+VS+ + +    + A K  R  +  +   QI +     H      P++V +Y A+  +  +Y+  EY  GGS+            +  P  AF    +   ++H  + L+  H+  ++H D+KP+NI </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>1.82805e-09</Hsp_evalue>
      <Hsp_query-from>671</Hsp_query-from>
      <Hsp_query-to>1075</Hsp_query-to>
      <Hsp_hit-from>50</Hsp_hit-from>
      <Hsp_hit-to>198</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>155</Hsp_align-len>
      <Hsp_qseq>FHELGALGHGHFGSVSRCVKRLDGCVYAVKRSRRPVAHS------------ADEQIALREVCAHAVLGQHPHVVQYYSAWA--EDNHMYIQNEYCSGGSV-----TDALLRSPGHAFPEWR-VRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIA</Hsp_qseq>
      <Hsp_hseq>FEILATLGNGQYGKVKLARDLGTGALVAIKILNRFEKRSGYSLQLKVENPRVNQEIEVMKRC------HHENVVELYEILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLIS</Hsp_hseq>
      <Hsp_midline>F  L  LG+G +G V        G + A+K   R    S             +++I + + C       H +VV+ Y      E   +Y+  EYCS G V         +++ G +   ++  R+++L V  GL Y+HS G+ H DIKPSN+ I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>2.66953e-09</Hsp_evalue>
      <Hsp_query-from>689</Hsp_query-from>
      <Hsp_query-to>1072</Hsp_query-to>
      <Hsp_hit-from>17</Hsp_hit-from>
      <Hsp_hit-to>146</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>132</Hsp_align-len>
      <Hsp_qseq>LGHGHFGSVSRCV-KRLDGCVYAVKR-SRRPVAHSADEQIALREVCAHAVLGQ--HPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFI</Hsp_qseq>
      <Hsp_hseq>LGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELL-SLLHKMG-TFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLL</Hsp_hseq>
      <Hsp_midline>LGHG + +V + + K+    +YA+K  S++ +   A  +    E     +L Q  H  +++ Y  + ++ ++Y   ++  GG +  +LL   G  F +   R     +   L +IHS G++H D+KP N+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>7.63106e-09</Hsp_evalue>
      <Hsp_query-from>755</Hsp_query-from>
      <Hsp_query-to>1075</Hsp_query-to>
      <Hsp_hit-from>154</Hsp_hit-from>
      <Hsp_hit-to>257</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>107</Hsp_align-len>
      <Hsp_qseq>VKRSRRPVAHSADEQIALREVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIA</Hsp_qseq>
      <Hsp_hseq>LERQKRLEKEIARDKRTVREASLGQIL-YHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQH--GSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMIS</Hsp_hseq>
      <Hsp_midline>++R +R     A ++  +RE     +L  HPH+ + +      NH Y+  EY SGG + D +++    +  E   R+    +A  L+Y+H+  +VH D+K  NI I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>7.71787e-09</Hsp_evalue>
      <Hsp_query-from>662</Hsp_query-from>
      <Hsp_query-to>1075</Hsp_query-to>
      <Hsp_hit-from>617</Hsp_hit-from>
      <Hsp_hit-to>748</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>STEFHELGALGHGHFGSVSRCVKRLDGCVYAVKRSRRPVAHSADEQIALREVCAHAVL----GQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIA</Hsp_qseq>
      <Hsp_hseq>STKYANLVKIGQGASGGVYTAYEIGTNVSVAIKQMNL-------EKQPKKELIINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVTHC---ILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLS</Hsp_hseq>
      <Hsp_midline>ST++  L  +G G  G V    +       A+K+          E+   +E+  + +L     +HP++V +  ++     +++  EY  GGS+TD +         E ++  +      GL ++HS G++H DIK  NI ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>9.63372e-09</Hsp_evalue>
      <Hsp_query-from>686</Hsp_query-from>
      <Hsp_query-to>1099</Hsp_query-to>
      <Hsp_hit-from>42</Hsp_hit-from>
      <Hsp_hit-to>178</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>139</Hsp_align-len>
      <Hsp_qseq>ALGHGHFGSVSRCVKRLDGCVYAVKRSRRPVAHSADEQI-ALREVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIAQRTLSSEL</Hsp_qseq>
      <Hsp_hseq>TLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKG--KFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPL</Hsp_hseq>
      <Hsp_midline> LG G FG V +      G   AVK   +        Q+ AL +         HP++V +   +   +  YI  +   GG + D +L+     F E    R+L+ +   ++Y+HS  +VH D+KP N+    ++  S L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>1.30002e-08</Hsp_evalue>
      <Hsp_query-from>665</Hsp_query-from>
      <Hsp_query-to>1072</Hsp_query-to>
      <Hsp_hit-from>86</Hsp_hit-from>
      <Hsp_hit-to>219</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>143</Hsp_align-len>
      <Hsp_qseq>TEFHELGALGHGHFGSVSRCVKRLDGCVYAVKRSRR-------PVAHSADEQIALREVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFI</Hsp_qseq>
      <Hsp_hseq>SDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVS-------HPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKS--QRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILL</Hsp_hseq>
      <Hsp_midline>++F  L  LG G FG V       +G  YA+K  ++        V H+ DE+  L  V        HP +++ +  + +   +++  +Y  GG +   L +S    FP    +     V   L Y+HS  +++ D+KP NI +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>2.05584e-08</Hsp_evalue>
      <Hsp_query-from>668</Hsp_query-from>
      <Hsp_query-to>1102</Hsp_query-to>
      <Hsp_hit-from>121</Hsp_hit-from>
      <Hsp_hit-to>284</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>171</Hsp_align-len>
      <Hsp_qseq>EFHELGALGHGHFGSVSRCVKRLDGCVYAVK---RSRRPVAHS-------ADEQIAL-------------REVCAHAVLGQ---HPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIAQRTLSSELE</Hsp_qseq>
      <Hsp_hseq>EFVE--TVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPPPKNEQDVLERQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQH--GSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISD---SSEIK</Hsp_hseq>
      <Hsp_midline>EF E   +G G  G V     R    V AVK   R+ +   H         +EQ  L             +     A LGQ   HPH+ + +      NH Y+  EY SGG + D +++    +  E + R+    +A  L Y+H+  +VH D+K  NI I+    SSE++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>2.3804e-08</Hsp_evalue>
      <Hsp_query-from>686</Hsp_query-from>
      <Hsp_query-to>1198</Hsp_query-to>
      <Hsp_hit-from>52</Hsp_hit-from>
      <Hsp_hit-to>224</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>175</Hsp_align-len>
      <Hsp_qseq>ALGHGHFGSVSRCVKRLDGCVYAVKRSRRPVAHSADEQI-ALREVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIAQRTLSSEL---EEGEPQSDAGRVNSRHVEEGDSRFLALEVLQQD</Hsp_qseq>
      <Hsp_hseq>TLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRIL-SRGK-FTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQD</Hsp_hseq>
      <Hsp_midline> LG G FG V +  K       A+K   +      + Q+  L E  +      HP++V +   +   +  YI  +  +GG + D +L S G  F E     +++ +   + Y+HS  +VH D+KP N+    ++ +S L   + G  +   G  +  +   G   ++A EVL QD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>4.40127e-08</Hsp_evalue>
      <Hsp_query-from>671</Hsp_query-from>
      <Hsp_query-to>1078</Hsp_query-to>
      <Hsp_hit-from>55</Hsp_hit-from>
      <Hsp_hit-to>187</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>FHELGALGHGHFGSVSRCVKRLDGCVYAVKRSRRPVAHSADEQIALREVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIAQ</Hsp_qseq>
      <Hsp_hseq>YQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMS--EQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDE</Hsp_hseq>
      <Hsp_midline>+  +  LG G FG V        G   A+K   + V   +D Q  +    ++  L +HPH+++ Y      + + +  EY  G  + D +++    +  E   RR    +   + Y H   +VH D+KP N+ + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>4.87652e-08</Hsp_evalue>
      <Hsp_query-from>803</Hsp_query-from>
      <Hsp_query-to>1072</Hsp_query-to>
      <Hsp_hit-from>179</Hsp_hit-from>
      <Hsp_hit-to>267</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>25</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>91</Hsp_align-len>
      <Hsp_qseq>ALREVCAHAVLGQH-PHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFI</Hsp_qseq>
      <Hsp_hseq>VLNEVAIHKLVSKNNPHCTKFIAFQESANYYYLVTELVTGGEIFDRIVQLT--CFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLF</Hsp_hseq>
      <Hsp_midline> L EV  H ++ ++ PH  ++ +     N+ Y+  E  +GG + D +++     F E   R ++  VA  ++++H +G+VH D+KP N+  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>7.87809e-08</Hsp_evalue>
      <Hsp_query-from>671</Hsp_query-from>
      <Hsp_query-to>1075</Hsp_query-to>
      <Hsp_hit-from>824</Hsp_hit-from>
      <Hsp_hit-to>958</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>139</Hsp_align-len>
      <Hsp_qseq>FHELGALGHGHFGSV----SRCVKRLDGCVYAVKRSRRPVAHSADEQIALREVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIA</Hsp_qseq>
      <Hsp_hseq>FVLLKVLGKGNFGKVILSKSKNTDRL-CAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGG---DLMWHVQNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLT</Hsp_hseq>
      <Hsp_midline>F  L  LG G+FG V    S+   RL   +  +K+      H  +   A ++V   A   +HP +   Y ++  +N +Y   E+  GG   D +           R +     V   L+Y H  G+++ D+K  NI + </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>1.18446e-07</Hsp_evalue>
      <Hsp_query-from>668</Hsp_query-from>
      <Hsp_query-to>1072</Hsp_query-to>
      <Hsp_hit-from>69</Hsp_hit-from>
      <Hsp_hit-to>201</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>EFHELGALGHGHFGSVSRCVKRLDGCVYAVKRSRRP-------VAHSADEQIALREVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFI</Hsp_qseq>
      <Hsp_hseq>DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLK-------LVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKS--QRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILL</Hsp_hseq>
      <Hsp_midline>+F  +  LG G FG V       +G  YA+K  ++        V H+ DE+  L+       L +HP +++ +  + +  ++++  +Y  GG +   L +S    FP    +     V   L Y+H+  +++ D+KP NI +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>1.52893e-07</Hsp_evalue>
      <Hsp_query-from>809</Hsp_query-from>
      <Hsp_query-to>1081</Hsp_query-to>
      <Hsp_hit-from>163</Hsp_hit-from>
      <Hsp_hit-to>250</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>25</Hsp_identity>
      <Hsp_positive>44</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>91</Hsp_align-len>
      <Hsp_qseq>REVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIAQR</Hsp_qseq>
      <Hsp_hseq>REIVIMKLIS-HTNVMALFEVWENKSELYLVLEYVDGGELFDYLV-SKG-KLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKK</Hsp_hseq>
      <Hsp_midline>RE+    ++  H +V+  +  W   + +Y+  EY  GG + D L+ S G   PE         +  G+ Y HS  + H D+KP N+ + ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>1.6606e-07</Hsp_evalue>
      <Hsp_query-from>686</Hsp_query-from>
      <Hsp_query-to>1075</Hsp_query-to>
      <Hsp_hit-from>321</Hsp_hit-from>
      <Hsp_hit-to>458</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>141</Hsp_align-len>
      <Hsp_qseq>ALGHGHFGSVSRCVKR----LDGC----VYAVKRSRRPVAHSADE--QIALREVCAHAVLGQHPHVVQYYSAWAEDNHMYIQ-NEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIA</Hsp_qseq>
      <Hsp_hseq>VLGKGAFGVVRICQKKNVSSQDGNKSEKLYAVKEFKRRTSESAEKYSKRLTSEFCISSSL-HHTNIVTTLDLFQDAKGEYCEVMEYCAGGDLFTLVVAAGKLEYMEADC--FFKQLIRGVVYMHEMGVCHRDLKPENLLLT</Hsp_hseq>
      <Hsp_midline> LG G FG V  C K+     DG     +YAVK  +R  + SA++  +    E C  + L  H ++V     + +    Y +  EYC+GG +   ++ +    + E         + RG+ Y+H +G+ H D+KP N+ + </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>1.77374e-07</Hsp_evalue>
      <Hsp_query-from>803</Hsp_query-from>
      <Hsp_query-to>1072</Hsp_query-to>
      <Hsp_hit-from>233</Hsp_hit-from>
      <Hsp_hit-to>321</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>91</Hsp_align-len>
      <Hsp_qseq>ALREVCAHAVLGQH-PHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFI</Hsp_qseq>
      <Hsp_hseq>VLKEVALHKTVSAGCSQIVAFIDFQETDSYYYIIQELLTGGEIFGEIVRLT--YFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLF</Hsp_hseq>
      <Hsp_midline> L+EV  H  +      +V +      D++ YI  E  +GG +   ++R     F E   R ++  +A  ++++HSLG+VH DIKP N+  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YHR079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:258244:261591:-1 gene:YHR079C transcript:YHR079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IRE1 description:Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; role in homeostatic adaptation to ER stress; Kar2p binds inactive Ire1p and releases from it upon ER stress [Source:SGD;Acc:S000001121]</Hit_def>
  <Hit_accession>YHR079C</Hit_accession>
  <Hit_len>1115</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>2.37698e-07</Hsp_evalue>
      <Hsp_query-from>689</Hsp_query-from>
      <Hsp_query-to>1075</Hsp_query-to>
      <Hsp_hit-from>680</Hsp_hit-from>
      <Hsp_hit-to>806</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>137</Hsp_align-len>
      <Hsp_qseq>LGHGHFGSVSRCVKRLDGCVYAVKRSRRPVAHSADEQIALREVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCS--------GGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIA</Hsp_qseq>
      <Hsp_hseq>LGYGSSGTVV-FQGSFQGRPVAVKRMLIDFC-----DIALMEIKLLTESDDHPNVIRYYCSETTDRFLYIALELCNLNLQDLVESKNVSDENLKLQ----KEYNPISLLRQIASGVAHLHSLKIIHRDLKPQNILVS</Hsp_hseq>
      <Hsp_midline>LG+G  G+V        G   AVKR            IAL E+        HP+V++YY +   D  +YI  E C+          +V+D  L+       E+    +L  +A G+ ++HSL ++H D+KP NI ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>3.55375e-07</Hsp_evalue>
      <Hsp_query-from>668</Hsp_query-from>
      <Hsp_query-to>1072</Hsp_query-to>
      <Hsp_hit-from>411</Hsp_hit-from>
      <Hsp_hit-to>546</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>138</Hsp_align-len>
      <Hsp_qseq>EFHELGALGHGHFGSVSRCVKRLDGCVYAVKRSRRPVAHSADE---QIALREVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFI</Hsp_qseq>
      <Hsp_hseq>DFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEG--RFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILL</Hsp_hseq>
      <Hsp_midline>+F  L  LG G FG V +  K+    +YA+K   + V    +E    I  R +         P +V    ++     +Y+  +Y SGG +   L +     F E R +  +  +   L ++H   +V+ D+KP NI +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YJL057C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:328118:330121:-1 gene:YJL057C transcript:YJL057C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IKS1 description:Protein kinase of unknown cellular role; putative serine/threonine kinase; expression is induced during mild heat stress; deletion mutants are hypersensitive to copper sulphate and resistant to sorbate; interacts with an N-terminal fragment of Sst2p [Source:SGD;Acc:S000003593]</Hit_def>
  <Hit_accession>YJL057C</Hit_accession>
  <Hit_len>667</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>3.82728e-07</Hsp_evalue>
      <Hsp_query-from>659</Hsp_query-from>
      <Hsp_query-to>1063</Hsp_query-to>
      <Hsp_hit-from>169</Hsp_hit-from>
      <Hsp_hit-to>355</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>56</Hsp_gaps>
      <Hsp_align-len>189</Hsp_align-len>
      <Hsp_qseq>FSTEFHELGALGHGHFGSVSRCVKRLDGC---VYAVKRSRRPVAHSAD-EQIALREVCAHAVLG-QHPHVVQYYSAWAEDNH---------------------MYIQNEYCSGGSVTDALLRSPGHAFPEW----------------------------RVRRMLLHVARGLRYIHSLGLVHMDIKPSN</Hsp_qseq>
      <Hsp_hseq>FRKFFKILSLLGNGARGSVYKVVHTIGNTELGVFALKKI--PIGNDMEWFNKCIREVKALSSLTHKSANLITYNHVWLEMDSSVGFVRSIDGSQSDSQEEVPCIFILQQYCSGGNLEDCILRKVFNRFSDTESPEERKKKFRTRKKNHGKSGEVGLSTEQLVSIIRDIARGLHELHSIGLIHRDLKPSN</Hsp_hseq>
      <Hsp_midline>F   F  L  LG+G  GSV + V  +      V+A+K+   P+ +  +     +REV A + L  +  +++ Y   W E +                      ++I  +YCSGG++ D +LR   + F +                             ++  ++  +ARGL  +HS+GL+H D+KPSN</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>5.33067e-07</Hsp_evalue>
      <Hsp_query-from>659</Hsp_query-from>
      <Hsp_query-to>892</Hsp_query-to>
      <Hsp_hit-from>595</Hsp_hit-from>
      <Hsp_hit-to>668</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>79</Hsp_align-len>
      <Hsp_qseq>FSTEFHELGALGHGHFGSVSRCVKRLDGCVYAVKRSRRPVAHSADE-QIALREVCAHAVLGQHPHVVQYYSAWAEDNHM</Hsp_qseq>
      <Hsp_hseq>YASDFEEIAVLGQGAFGQVVKARNALDSRYYAIKKIR----HTEEKLSTILSEVMLLASL-NHQYVVRYYAAWLEEDSM</Hsp_hseq>
      <Hsp_midline>++++F E+  LG G FG V +    LD   YA+K+ R    H+ ++    L EV   A L  H +VV+YY+AW E++ M</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YOR267C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:822588:824867:-1 gene:YOR267C transcript:YOR267C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRK1 description:Protein kinase; implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005793]</Hit_def>
  <Hit_accession>YOR267C</Hit_accession>
  <Hit_len>759</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>5.38182e-07</Hsp_evalue>
      <Hsp_query-from>659</Hsp_query-from>
      <Hsp_query-to>1216</Hsp_query-to>
      <Hsp_hit-from>210</Hsp_hit-from>
      <Hsp_hit-to>400</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>200</Hsp_align-len>
      <Hsp_qseq>FSTEFHELGAL-GHGHFGSVSRCVKRLDGCVYAVK--RSRRP---VAHSADEQIALREVCAHAVLGQHPHVVQYYSAWAED--NHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIAQRTLSSELEEGE------PQSDAGRVNSRHVEEGDSRFLALEVLQQDYLASPQ</Hsp_qseq>
      <Hsp_hseq>LAQKYGKLGKLLGSGAGGSVKVLVRPTDGATFAVKEFRPRKPNESVKEYAKKCTA--EFCIGSTL-HHPNVIETVDVFSDSKQNKYYEVMEYCP----IDFFAVVMTGKMSRGEINCCLKQLTEGVKYLHSMGLAHRDLKLDNCVMTSQGILKLIDFGSAVVFRYPFEDG--VTMAHGIVGSDPYLAPEVITSTKSYDPQ</Hsp_hseq>
      <Hsp_midline> + ++ +LG L G G  GSV   V+  DG  +AVK  R R+P   V   A +  A  E C  + L  HP+V++    +++   N  Y   EYC      D              +   L  +  G++Y+HS+GL H D+K  N  +  + +   ++ G       P  D   V   H   G   +LA EV+       PQ</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YFL033C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:69115:74427:-1 gene:YFL033C transcript:YFL033C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM15 description:Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase [Source:SGD;Acc:S000001861]</Hit_def>
  <Hit_accession>YFL033C</Hit_accession>
  <Hit_len>1770</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>6.05257e-07</Hsp_evalue>
      <Hsp_query-from>668</Hsp_query-from>
      <Hsp_query-to>1072</Hsp_query-to>
      <Hsp_hit-from>793</Hsp_hit-from>
      <Hsp_hit-to>926</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>EFHELGALGHGHFGSVSRCVKRLDGCVYAVKRSRRPVAHSADEQIALR-EVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFI</Hsp_qseq>
      <Hsp_hseq>DYDILKPISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDKPYVARLFASFQNKDNLFLVMEYLPGGDLA-TLIKMMGYLPDQW-AKQYLTEIVVGVNDMHQNGIIHHDLKPENLLI</Hsp_hseq>
      <Hsp_midline>++  L  +  G +GSV    K+L G  +A+K  R+    + ++   ++ E     V    P+V + ++++   +++++  EY  GG +   L++  G+   +W  ++ L  +  G+  +H  G++H D+KP N+ I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>7.26047e-07</Hsp_evalue>
      <Hsp_query-from>671</Hsp_query-from>
      <Hsp_query-to>1075</Hsp_query-to>
      <Hsp_hit-from>133</Hsp_hit-from>
      <Hsp_hit-to>286</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>156</Hsp_align-len>
      <Hsp_qseq>FHELGALGHGHFGSVSRCVKRLDGCVYAVK-------RSRRPVAHSADEQIALREVCAH--AVLGQ--HPHVVQYYSAWAE--DNHMYIQNEYCSGGSV-------TDALLRSPGH-AFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIA</Hsp_qseq>
      <Hsp_hseq>YEIIKELGHGQHGKVKLARDILSKQLVAIKIVDRHEKKQRKFFTFIKSSKISENDKIKREIAIMKKCHHKHVVQLIEVLDDLKSRKIYLVLEYCSRGEVKWCPPDCMESDAKGPSLLSFQE--TREILRGVVLGLEYLHYQGIIHRDIKPANLLIS</Hsp_hseq>
      <Hsp_midline>+  +  LGHG  G V      L   + A+K       + R+        +I+  +      A++ +  H HVVQ      +     +Y+  EYCS G V        ++  + P   +F E   R +L  V  GL Y+H  G++H DIKP+N+ I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>7.40082e-07</Hsp_evalue>
      <Hsp_query-from>803</Hsp_query-from>
      <Hsp_query-to>1075</Hsp_query-to>
      <Hsp_hit-from>131</Hsp_hit-from>
      <Hsp_hit-to>216</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>93</Hsp_align-len>
      <Hsp_qseq>ALREVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEW--RVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIA</Hsp_qseq>
      <Hsp_hseq>AMYEVDIQTKIGRHQNI----AALLDFFDSYIIMEYCSGGDLYEAI---KADAVPKKTKSITHIITQIMDAIEYVHNKGIYHRDIKPENILIS</Hsp_hseq>
      <Hsp_midline>A+ EV     +G+H ++    +A  +    YI  EYCSGG + +A+      A P+    +  ++  +   + Y+H+ G+ H DIKP NI I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>7.61365e-07</Hsp_evalue>
      <Hsp_query-from>668</Hsp_query-from>
      <Hsp_query-to>1072</Hsp_query-to>
      <Hsp_hit-from>178</Hsp_hit-from>
      <Hsp_hit-to>311</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>144</Hsp_align-len>
      <Hsp_qseq>EFHELGALGHGHFGSV---------SRCVKRLDGCVYAVKRSRRPVAHSADEQIALREVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFI</Hsp_qseq>
      <Hsp_hseq>DFKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKK--VKYVSIEKTALQK------LNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFL-SLMKKYG-SLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILL</Hsp_hseq>
      <Hsp_midline>+F     +G G + +V          R   ++    Y +++ +  V + + E+ AL++      L   P VV+ +S + +++ +Y   EY   G    +L++  G +  E   R     +   + Y+HS G++H DIKP NI +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>1.22629e-06</Hsp_evalue>
      <Hsp_query-from>842</Hsp_query-from>
      <Hsp_query-to>1072</Hsp_query-to>
      <Hsp_hit-from>513</Hsp_hit-from>
      <Hsp_hit-to>587</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>42</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>77</Hsp_align-len>
      <Hsp_qseq>HPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFI</Hsp_qseq>
      <Hsp_hseq>HENIVTYYGASQEGGNLNIFLEYVPGGSVS-SMLNNYG-PFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILI</Hsp_hseq>
      <Hsp_midline>H ++V YY A  E  ++ I  EY  GGSV+ ++L + G  F E  +      +  G+ Y+H   ++H DIK +NI I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>1.50331e-06</Hsp_evalue>
      <Hsp_query-from>743</Hsp_query-from>
      <Hsp_query-to>1075</Hsp_query-to>
      <Hsp_hit-from>130</Hsp_hit-from>
      <Hsp_hit-to>236</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>111</Hsp_align-len>
      <Hsp_qseq>CVYAVKRSRRPVAHSADEQIALREVCAHAVLGQHPHVVQYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIA</Hsp_qseq>
      <Hsp_hseq>CALKVMEKEEIIKYNLQKQFR-REVEIQTSLN-HPNLTKSYGYFHDEKRVYLLMEYLVNGEMY-KLLRLHG-PFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIG</Hsp_hseq>
      <Hsp_midline>C   V      + ++  +Q   REV     L  HP++ + Y  + ++  +Y+  EY   G +   LLR  G  F +      +  +A  L Y+H   ++H DIKP NI I </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>1.78749e-06</Hsp_evalue>
      <Hsp_query-from>809</Hsp_query-from>
      <Hsp_query-to>1195</Hsp_query-to>
      <Hsp_hit-from>604</Hsp_hit-from>
      <Hsp_hit-to>742</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>139</Hsp_align-len>
      <Hsp_qseq>REVCAHAVL----GQHPHVVQYYSAWA-EDNHMYIQNEYCSGGSVTDALLRSPGH-----AFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIAQRTLSSELEEGEPQSDAGRVNSRHVEEGDSRFLALEVLQQ</Hsp_qseq>
      <Hsp_hseq>KELIVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQ</Hsp_hseq>
      <Hsp_midline>+E+  + +L     +H ++V +  A+   D+ +++  E+  GGS+TD +  SP +        E ++  ++    +GL+++H   ++H DIK  N+ +  R      + G       + + R    G   ++A EV++Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>3.38446e-06</Hsp_evalue>
      <Hsp_query-from>662</Hsp_query-from>
      <Hsp_query-to>1081</Hsp_query-to>
      <Hsp_hit-from>20</Hsp_hit-from>
      <Hsp_hit-to>155</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>143</Hsp_align-len>
      <Hsp_qseq>STEFHELGALGHGHFGSVSRCVKRLDGCVYAVKRSRRPVAHSADEQIALREVCAHAVLGQHPHVV---QYYSAWAEDNHMYIQNEYCSGGSVTDALLRSPGHAFPEWRVRRMLLHVARGLRYIHSLGLVHMDIKPSNIFIAQR</Hsp_qseq>
      <Hsp_hseq>TNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHL-RHENLICLQDIFLSPLED--IYFVTE-LQGTDLHRLLQTRP---LEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINEN</Hsp_hseq>
      <Hsp_midline>+  +++L  +G G FG V      L     A+K+  +P + +   +   RE+     L +H +++     + +  ED  +Y   E   G  +   L   P     +  V+  L  + RGL+Y+HS G++H D+KPSNI I + </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>1955476955</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061697-RA transcript Note:&quot;Similar to BRSK2 Serine/threonine-protein kinase BRSK2 (Homo sapiens)&quot; offset:0 AED:0.28 eAED:0.28 QI:0|0|0|0.92|1|1|13|0|500</Iteration_query-def>
  <Iteration_query-len>1503</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>209.149</Hsp_bit-score>
      <Hsp_score>531</Hsp_score>
      <Hsp_evalue>6.18131e-61</Hsp_evalue>
      <Hsp_query-from>61</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>69</Hsp_hit-from>
      <Hsp_hit-to>294</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>102</Hsp_identity>
      <Hsp_positive>156</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>227</Hsp_align-len>
      <Hsp_qseq>VKLGIHSVTGRKVAVKIVNREKLSESVL----------MKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSI--WDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL------------VLLEKVKRGVFHMPHFIPPDCQALLRGMIEVDAEKR</Hsp_qseq>
      <Hsp_hseq>VKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEY-AGNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGAAGLIKRMLIVNPLNR</Hsp_hseq>
      <Hsp_midline>VKL  H+ TG+KVA+KI+N++ L++S +          ++L+ HPH++KLYDV ++K  + +V+E+ +G ELFDY+V++ +++ +EARRFF+QIISA+++CH H I   DLKPENLLLDE  N++IADFG++++    + L+TSCGSP+YA PEVI G+ Y G + DVWSCGVIL+ +L            VL + +  GV+ +P F+ P    L++ M+ V+   R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>204.527</Hsp_bit-score>
      <Hsp_score>519</Hsp_score>
      <Hsp_evalue>1.87082e-57</Hsp_evalue>
      <Hsp_query-from>133</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>164</Hsp_hit-from>
      <Hsp_hit-to>357</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>101</Hsp_identity>
      <Hsp_positive>137</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>194</Hsp_align-len>
      <Hsp_qseq>ESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKN-NIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLV------------LLEKVKRGVFHMPHFIPPDCQALLRGMIEVDAEKR</Hsp_qseq>
      <Hsp_hseq>EIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMPSNLSSEARDLISKILVIDPEKR</Hsp_hseq>
      <Hsp_midline>E V+MKLI H +V+ L++V+ENK  LYLVLE+V GGELFDYLV KG+L  +EA  +F+QI+  + +CHS +I   DLKPENLLLD+KN  I+IADFGMA+L++ + LL+TSCGSPHYA PE++ G  Y G  +DVWSCG++LFALL             LL KV+ G + MP  +  + + L+  ++ +D EKR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>202.986</Hsp_bit-score>
      <Hsp_score>515</Hsp_score>
      <Hsp_evalue>5.2041e-57</Hsp_evalue>
      <Hsp_query-from>61</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>33</Hsp_hit-from>
      <Hsp_hit-to>277</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>113</Hsp_identity>
      <Hsp_positive>148</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>245</Hsp_align-len>
      <Hsp_qseq>VKLGIHSVTGRKVAVKIVNREKLS------------------------ESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSI--WDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL--------------VLLEKVKRGVFHMPH--FIPPDCQALLRGMIEVDAEKR</Hsp_qseq>
      <Hsp_hseq>VQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERR</Hsp_hseq>
      <Hsp_midline>V+L  +  TG++ AVK++++   +                        E ++MKL+ HP+VL+LYDV+E    LYLVLE+   GELF+ LV++G L   EA RFFRQII  + +CH+  I   DLKPENLLLD K NI+IADFGMA+L+    LLETSCGSPHYA PE++ G  Y G  +DVWSCGVILFALL               LL KV++G F MP    I  + Q L+R ++ VD E+R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>196.823</Hsp_bit-score>
      <Hsp_score>499</Hsp_score>
      <Hsp_evalue>6.22987e-55</Hsp_evalue>
      <Hsp_query-from>61</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>35</Hsp_hit-from>
      <Hsp_hit-to>273</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>111</Hsp_identity>
      <Hsp_positive>142</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>239</Hsp_align-len>
      <Hsp_qseq>VKLGIHSVTGRKVAVKIVNREKLS------------------ESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSI--WDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLV--------------LLEKVKRGVFHMPH--FIPPDCQALLRGMIEVDAEKR</Hsp_qseq>
      <Hsp_hseq>VQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQR</Hsp_hseq>
      <Hsp_midline>V+L  H  TG + AVK++++   +                  E V+MKL+ HP+VL LYDV+E    LYL+LE+   GELF+ LV  G L  +EA   FRQII  + +CH+  I   DLKPENLLLD   NI+IADFGMA+LQ    LLETSCGSPHYA PE++ G  Y+G  +DVWSCGVILFALL               LL KV++G F MP+   I  D Q L+  ++ VD  +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>144.436</Hsp_bit-score>
      <Hsp_score>363</Hsp_score>
      <Hsp_evalue>2.69468e-37</Hsp_evalue>
      <Hsp_query-from>91</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>75</Hsp_hit-from>
      <Hsp_hit-to>301</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>86</Hsp_identity>
      <Hsp_positive>125</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>227</Hsp_align-len>
      <Hsp_qseq>RKVAVKIVNREKLS-----------ESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSI--WDLKPENLLLDEKNNIRIADFGMAS-LQVGDSLLETSCGSPHYACPE-VIRGEKYDGRKADVWSCGVILFALLV-------------------LLEKVKRGVFHMPHFIPPDCQALLRGMIEVDAEKR</Hsp_qseq>
      <Hsp_hseq>KQVAIKLIKRDSISNDYRKEVKIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVNEFCSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGRLYNYINSTPLKFPDYILPIPRDLLRRMLVSDPKKR</Hsp_hseq>
      <Hsp_midline>++VA+K++ R+ +S           E   +K + HP+++KL +V +N +Y+ +VLE+  GGE + Y+ KK RL    A R F Q+IS + + HS  +   DLK ENLLLD+  N+ I DFG  +     + L++TSCGSP YA PE VI  E Y+ RKAD+WSCGVIL+A+L                    L   +       P +I P  + LLR M+  D +KR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>137.117</Hsp_bit-score>
      <Hsp_score>344</Hsp_score>
      <Hsp_evalue>9.68126e-35</Hsp_evalue>
      <Hsp_query-from>106</Hsp_query-from>
      <Hsp_query-to>675</Hsp_query-to>
      <Hsp_hit-from>183</Hsp_hit-from>
      <Hsp_hit-to>388</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>125</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>206</Hsp_align-len>
      <Hsp_qseq>KIVNREK--LSESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSI--WDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL------------VLLEKVKRGVFHMPHFIPPDCQALLRGMIEVDAEKRGI</Hsp_qseq>
      <Hsp_hseq>KEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKIKQGKVEYPQHLSIEVISLLSKMLVVDPKRRAT</Hsp_hseq>
      <Hsp_midline>K ++R+K  + E+ L +++ HPH+ +L+++     + Y++ E+VSGG+L DY+++ G +   +AR+F R I SAL + H+++I   DLK EN+++ + + I+I DFG++++      L T CGS ++A PE+++   Y G + DVWS GV+LF L+            VL EK+K+G    P  +  +  +LL  M+ VD ++R  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>136.732</Hsp_bit-score>
      <Hsp_score>343</Hsp_score>
      <Hsp_evalue>1.07644e-34</Hsp_evalue>
      <Hsp_query-from>61</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>60</Hsp_hit-from>
      <Hsp_hit-to>301</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>85</Hsp_identity>
      <Hsp_positive>131</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>242</Hsp_align-len>
      <Hsp_qseq>VKLGIHSVTG-----RKVAVKIVNREKLSESV-----------LMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSI--WDLKPENLLLDEKNNIRIADFGMASLQVGDS-LLETSCGSPHYACPE-VIRGEKYDGRKADVWSCGVILFALLV-------------------LLEKVKRGVFHMPHFIPPDCQALLRGMIEVDAEKR</Hsp_qseq>
      <Hsp_hseq>VKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARLYKYITQTPLKFPEYITPIPRDLLRRILVPNPRRR</Hsp_hseq>
      <Hsp_midline>VKLG    +      ++VA+K++ R+ + +              +K + HP+++ L +V +N KY+ +VLE VSGGE + Y+ +K RL    A R F Q+IS +++ H   +   DLK ENLLLD+  N+ I DFG  +    D+ L++TSCGSP YA PE V+  + Y+ RKADVWSCGVIL+A+L                    L + + +     P +I P  + LLR ++  +  +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>132.88</Hsp_bit-score>
      <Hsp_score>333</Hsp_score>
      <Hsp_evalue>2.77638e-33</Hsp_evalue>
      <Hsp_query-from>76</Hsp_query-from>
      <Hsp_query-to>675</Hsp_query-to>
      <Hsp_hit-from>142</Hsp_hit-from>
      <Hsp_hit-to>367</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>126</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>226</Hsp_align-len>
      <Hsp_qseq>HSVTGRKVAVKIVNREK------------LSESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSI--WDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL------------VLLEKVKRGVFHMPHFIPPDCQALLRGMIEVDAEKRGI</Hsp_qseq>
      <Hsp_hseq>HSLPSPKNESEILERQKRLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYPSHLSIEVISLLTRMIVVDPLRRAT</Hsp_hseq>
      <Hsp_midline>HS+   K   +I+ R+K            + E+ L +++ HPH+ +L+++     + Y++ E+VSGG+L DY+++ G L    AR+F R I SAL + H+++I   DLK EN+++     I+I DFG++++      L T CGS ++A PE+++ + Y G + D+WS G++L+ L+            +L EK+K+G    P  +  +  +LL  MI VD  +R  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>124.405</Hsp_bit-score>
      <Hsp_score>311</Hsp_score>
      <Hsp_evalue>6.62375e-32</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>92</Hsp_hit-from>
      <Hsp_hit-to>307</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>121</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>219</Hsp_align-len>
      <Hsp_qseq>TGRKVAVKIVNREKL----------SESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLV------------LLEKVKRGVFHMPHFIPPDCQALLRGMIEVDAEKR</Hsp_qseq>
      <Hsp_hseq>NGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFA--KEVQTVTWTLCGTPDYIAPEVITTKPYN-KSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRR</Hsp_hseq>
      <Hsp_midline> GR  A+K++ ++++           E  ++KL+EHP +++++  +++ + +++V++++ GGELF  L K  R     A+ +  ++I AL++ H+H+I   DLKPEN+LLD   +I+I DFG A  +   ++  T CG+P Y  PEVI  + Y+ +  D WS GV+++ +L               EK+ +G    P +  PD   LL  +I  D  +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>121.709</Hsp_bit-score>
      <Hsp_score>304</Hsp_score>
      <Hsp_evalue>8.81547e-30</Hsp_evalue>
      <Hsp_query-from>61</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>212</Hsp_hit-from>
      <Hsp_hit-to>454</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>129</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>243</Hsp_align-len>
      <Hsp_qseq>VKLGIHSVTGRKVAVKIVNREKL--------SESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNN--IRIADFGMASLQVGDSLLETSCGSPHYACPEVIRG-------EKYDGRK-----ADVWSCGVILFALLV------------LLEKVKRGVFH---MPHF-IPPDCQALLRGMIEVDAEKR</Hsp_qseq>
      <Hsp_hseq>VKKAIERTTGKTFAVKIISKRKVIGNMDGVTRELEVLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGPLKDFRISEEARDFIDSLLQVDPNNR</Hsp_hseq>
      <Hsp_midline>VK  I   TG+  AVKI+++ K+         E  +++ + HP +++L   YE+ +  Y+V+E VSGG+L D++   G +     R   RQI++A+ + HS  I   DLKP+N+L+++ +   ++I DFG+A +Q   S ++T CG+  Y  PEVIRG       ++Y+ R       D+WS G +++ +L             L +++ RG +H   +  F I  + +  +  +++VD   R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>112.079</Hsp_bit-score>
      <Hsp_score>279</Hsp_score>
      <Hsp_evalue>1.9107e-27</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>110</Hsp_hit-from>
      <Hsp_hit-to>325</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>219</Hsp_align-len>
      <Hsp_qseq>TGRKVAVKIVNREKL----------SESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLV------------LLEKVKRGVFHMPHFIPPDCQALLRGMIEVDAEKR</Hsp_qseq>
      <Hsp_hseq>NGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKY-VPD-VTYTLCGTPDYIAPEVVSTKPYN-KSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSER</Hsp_hseq>
      <Hsp_midline> GR  A+K + +  +           E  ++ ++ HP +++++  +++ + +++V++++ GGELF  L K  R     A+ +  ++  AL++ HS  I   DLKPEN+LLD+  +I+I DFG A   V D +  T CG+P Y  PEV+  + Y+ +  D WS GV+++ +L               E +       P F  PD Q LL+ +I  D  +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>109.383</Hsp_bit-score>
      <Hsp_score>272</Hsp_score>
      <Hsp_evalue>1.54564e-26</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>109</Hsp_hit-from>
      <Hsp_hit-to>324</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>219</Hsp_align-len>
      <Hsp_qseq>TGRKVAVKIVNREKL----------SESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLV------------LLEKVKRGVFHMPHFIPPDCQALLRGMIEVDAEKR</Hsp_qseq>
      <Hsp_hseq>NGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKY-VPD-VTYTLCGTPDYIAPEVVSTKPYN-KSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRDLSQR</Hsp_hseq>
      <Hsp_midline> GR  A+K++ +E +           E +++ ++ HP +++++  +++ + ++++++++ GGELF  L K  R     A+ +  ++  AL++ HS  I   DLKPEN+LLD+  +I+I DFG A   V D +  T CG+P Y  PEV+  + Y+ +  D WS G++++ +L               EK+       P F   D + LL  +I  D  +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>110.153</Hsp_bit-score>
      <Hsp_score>274</Hsp_score>
      <Hsp_evalue>1.6665e-26</Hsp_evalue>
      <Hsp_query-from>58</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>50</Hsp_hit-from>
      <Hsp_hit-to>233</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>185</Hsp_align-len>
      <Hsp_qseq>LVKLGIHSVTGRKVAVKIVNREKL-----------SESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSI--WDLKPENLLLDEKNN---IRIADFGMAS-LQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL</Hsp_qseq>
      <Hsp_hseq>VVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGH-GKPCDIWSIGVITYTLL</Hsp_hseq>
      <Hsp_midline>+V+   ++ TG  VAVKI+ ++ L            E  +++ + HP+++   D +E+K   Y++ +   GGELFD ++KKG+ T ++A R   +I+SA+ + HS +I   DLKPENLL  +K++   + +ADFG+A  L+  + LL    GS  Y  PEV+  + + G+  D+WS GVI + LL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>107.457</Hsp_bit-score>
      <Hsp_score>267</Hsp_score>
      <Hsp_evalue>2.08875e-25</Hsp_evalue>
      <Hsp_query-from>73</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>47</Hsp_hit-from>
      <Hsp_hit-to>217</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>175</Hsp_align-len>
      <Hsp_qseq>IHSVTGRKVAVKIVNREKLSESVLM-KLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCH-----SHSIWDLKPENLLLDEKNNIRIADFGMAS-LQVGDSLLETSC---GSPHYACPEVIRGEK-YDGRKADVWSCGVILFALLV</Hsp_qseq>
      <Hsp_hseq>IHVPTCKKMGLS--DKDITKEVVLQSKCSKHPNVLRLIDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHR--DIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLT</Hsp_hseq>
      <Hsp_midline>IH  T +K+ +   +++   E VL  K  +HP+VL+L D   +K+Y++++LE   GG+LFD +     +    A+ +F+Q++SA+++ H     +H   D+KPEN+LLD+  N+++ADFG+AS  +  D  L  S    GSP Y  PEV+  E+ Y   + D+WS G++LF LL </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>105.145</Hsp_bit-score>
      <Hsp_score>261</Hsp_score>
      <Hsp_evalue>1.0991e-24</Hsp_evalue>
      <Hsp_query-from>58</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>213</Hsp_hit-from>
      <Hsp_hit-to>415</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>204</Hsp_align-len>
      <Hsp_qseq>LVKLGIHSVTGRKVAVKIV----------NREKLSESVLMKLIEHPHVLKLYDVY-----ENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLL----------------DEKN---NIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL</Hsp_qseq>
      <Hsp_hseq>LVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKKGYTS-KVDLWSAGVILYVCL</Hsp_hseq>
      <Hsp_midline>LVK   +  TG++VAVKI           N++   E+ ++  ++HP+++ L D +     +++   YLVLE +  GELF+ +V+K  L   E++  F+Q+++ L + H  +I   D+KPEN+LL                DE      ++IADFG+A          T CG+P Y  PEV+  + Y   K D+WS GVIL+  L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>105.916</Hsp_bit-score>
      <Hsp_score>263</Hsp_score>
      <Hsp_evalue>1.53201e-24</Hsp_evalue>
      <Hsp_query-from>61</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>55</Hsp_hit-from>
      <Hsp_hit-to>227</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>173</Hsp_align-len>
      <Hsp_qseq>VKLGIHSVTGRKVAVKIVNREK---LSESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHS-HSI-WDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLV</Hsp_qseq>
      <Hsp_hseq>VYLALHRPTHRKVCLKTSDKNDPNIVREVFYHRQFDFPYITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTRECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLIT</Hsp_hseq>
      <Hsp_midline>V L +H  T RKV +K  ++     + E    +  + P++ KLY+V   +  +++ LE+  G EL+D+L+   R++  E    F QI  A+ + HS H +  DLK EN+LLD+  N ++ DFG     +  + LET CG+  Y  PE+I    YDG K D+WS GVIL+ L+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>103.99</Hsp_bit-score>
      <Hsp_score>258</Hsp_score>
      <Hsp_evalue>4.43667e-24</Hsp_evalue>
      <Hsp_query-from>127</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>390</Hsp_hit-from>
      <Hsp_hit-to>584</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>196</Hsp_align-len>
      <Hsp_qseq>LSESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMASLQVGDS-LLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL------------VLLEKVKRGVFHMPHFIPPDCQALLRGMIEVDAEKR</Hsp_qseq>
      <Hsp_hseq>LAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYT-KTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAAKDLLIGLLSRDPSRR</Hsp_hseq>
      <Hsp_midline>L+E  ++  ++ P ++ L   +++ + LYLVL  ++GGELF +L  +GR +   +R +  +++ ALD  H   +   DLKPEN+LLD + +I + DFG+  L + D+   +T CG+P Y  PE++ G+ Y  +  D W+ G++L+ ++            V+ +K+ +     P    P  + LL G++  D  +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>99.7525</Hsp_bit-score>
      <Hsp_score>247</Hsp_score>
      <Hsp_evalue>1.93217e-23</Hsp_evalue>
      <Hsp_query-from>76</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>123</Hsp_hit-from>
      <Hsp_hit-to>343</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>222</Hsp_align-len>
      <Hsp_qseq>HSVTGRKVAVKIVNREKLSESVLMKL----------IEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLV----LLEKVKRGVF--------HMPHFIPPDCQALLRGMIEVDAEKR</Hsp_qseq>
      <Hsp_hseq>HRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYD-HTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMPSNISQDAQDLILKLLKYDPKDR</Hsp_hseq>
      <Hsp_midline>H  TG   A+K++ +E++ +  L K           + HP++ K Y  + ++K +YL++E++  GE++  L   G      A  +  QI +ALD+ H  +I   D+KPEN+L+   N I++ DFG + +   ++  +T CG+  Y  PE++   +YD    D W+ GV+ F LL       E++K   +         MP  I  D Q L+  +++ D + R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>101.679</Hsp_bit-score>
      <Hsp_score>252</Hsp_score>
      <Hsp_evalue>2.74634e-23</Hsp_evalue>
      <Hsp_query-from>79</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>111</Hsp_hit-from>
      <Hsp_hit-to>325</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>216</Hsp_align-len>
      <Hsp_qseq>SVTGRKVAVKIVNREKLSESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMASLQVGDSLLE-TSCGSPHYACPEVIRGEKYDGR--KADVWSCGVILFALLV------------LLEKVKRGVFHMPHFIP--PDCQALLRGMIEVDAEKR</Hsp_qseq>
      <Hsp_hseq>TVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMG-KHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRDKPISDEGKILIRDILSLDPIER</Hsp_hseq>
      <Hsp_midline>+V    +  +   ++ LSE  + K + HP++++  D +E+   +Y++LE    G L + L ++  LT  E R F  QI  A+ + HS  +   DLK  N+  D   N++I DFG+A++   +S  + T CG+P+Y  PEV+ G K+ G   + D+WS GV+L+ALL+            + E++K   F  P   P   + + L+R ++ +D  +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>101.293</Hsp_bit-score>
      <Hsp_score>251</Hsp_score>
      <Hsp_evalue>3.13453e-23</Hsp_evalue>
      <Hsp_query-from>127</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>393</Hsp_hit-from>
      <Hsp_hit-to>587</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>196</Hsp_align-len>
      <Hsp_qseq>LSESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSI--WDLKPENLLLDEKNNIRIADFGMASLQV-GDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVLL--------EKVKRGVFHMPHFIPP----DCQALLRGMIEVDAEKR</Hsp_qseq>
      <Hsp_hseq>LAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGY-TKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSRDPTRR</Hsp_hseq>
      <Hsp_midline>L+E  ++  ++ P ++ L   +++ + LY VL  ++GGELF +L K+GR     AR +  +++ ALD  H   +   DLKPEN+LLD + +I + DFG+  L +  D   +T CG+P Y  PE++ G  Y  +  D W+ GV+L+ +L  L         K+ + +   P   P     D + LL G++  D  +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>99.3673</Hsp_bit-score>
      <Hsp_score>246</Hsp_score>
      <Hsp_evalue>5.90968e-23</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>69</Hsp_hit-from>
      <Hsp_hit-to>243</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>176</Hsp_align-len>
      <Hsp_qseq>TGRKVAVKIVNREKLS-----------ESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSI--WDLKPENLL-LDEKNN--IRIADFGMA-SLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL</Hsp_qseq>
      <Hsp_hseq>TNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGH-GKPCDIWSIGVITYTLL</Hsp_hseq>
      <Hsp_midline>T   VA+KI+ ++ L            E  +++ + HP+++   D +E+K   Y+V +  +GGELFD ++ +G+ T  +A     QI+ A+++ HS ++   DLKPEN+L +D+  N  + IADFG+A  L+  + L+  + GS  Y  PEV+  + + G+  D+WS GVI + LL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.9745</Hsp_bit-score>
      <Hsp_score>232</Hsp_score>
      <Hsp_evalue>1.07285e-20</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>201</Hsp_hit-from>
      <Hsp_hit-to>384</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>185</Hsp_align-len>
      <Hsp_qseq>TGRKVAVKIVNREKL-----------SESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSI--WDLKPENLLLDEKNNIRIADFGMASL--QVGDSL------LETSC----GSPHYACPEVIRGEKYDGRKADVWSCGVILFALLV</Hsp_qseq>
      <Hsp_hseq>TKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYR-CDIWAFGCILFQMIA</Hsp_hseq>
      <Hsp_midline>T ++ A K++N+E L            ++ L KL   P V++L+  ++++  LY +LE+   G+    + K G L    AR +  QII A+D+ HS+ I   D+KPEN+LLD +  I++ DFG A L     +S+      L T      G+  Y  PE++     D R  D+W+ G ILF ++ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>92.8189</Hsp_bit-score>
      <Hsp_score>229</Hsp_score>
      <Hsp_evalue>2.14405e-20</Hsp_evalue>
      <Hsp_query-from>163</Hsp_query-from>
      <Hsp_query-to>558</Hsp_query-to>
      <Hsp_hit-from>473</Hsp_hit-from>
      <Hsp_hit-to>605</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>134</Hsp_align-len>
      <Hsp_qseq>PHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSI--WDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFAL</Hsp_qseq>
      <Hsp_hseq>PFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR-TNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEM</Hsp_hseq>
      <Hsp_midline>P ++ L   ++    LYLV +++SGGELF +L K+GR +   A+ +  +++ AL+  H + I   DLKPEN+LLD   NI + DFG++   + D    T CG+  Y  PE++  E    +  D WS GV++F +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>91.6633</Hsp_bit-score>
      <Hsp_score>226</Hsp_score>
      <Hsp_evalue>3.09247e-20</Hsp_evalue>
      <Hsp_query-from>127</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>200</Hsp_hit-from>
      <Hsp_hit-to>357</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>159</Hsp_align-len>
      <Hsp_qseq>LSESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSI--WDLKPENLLLDEKNNIRIADFGMASLQVGDSLLE-----------TSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLV</Hsp_qseq>
      <Hsp_hseq>FAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAY-SQNCDWYSLGCLLYDMLV</Hsp_hseq>
      <Hsp_midline> +E  ++  IEHP+++KL+  + +   LYL+L+++ GGELF +L + G L       +  +I  AL F H+  +   DLKPEN LL+++ ++ + DFG++     DS ++           +  G+P Y  PE++ G+ Y  +  D +S G +L+ +LV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.5077</Hsp_bit-score>
      <Hsp_score>223</Hsp_score>
      <Hsp_evalue>1.13492e-19</Hsp_evalue>
      <Hsp_query-from>73</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>43</Hsp_hit-from>
      <Hsp_hit-to>313</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>121</Hsp_positive>
      <Hsp_gaps>74</Hsp_gaps>
      <Hsp_align-len>272</Hsp_align-len>
      <Hsp_qseq>IHSVTGRKVAVKIVNREKLS----------ESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLT---------------PKEARR---------FFRQIISALDFCHSHSI--WDLKPENLLL--------DEKNN-------------IRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFAL------------LVLLEKVKRG--VFHMPHF--IPPDCQALLRGMIEVDAEKR</Hsp_qseq>
      <Hsp_hseq>LTSDKSQHVAIKEVSRAKLKNKKLLENLEIEIAILKKIKHPHIVGLIDCERTSTDFYLIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVVFEMCCGTPPFRASNHLELFKKIKRANDVITFPSYCNIEPELKELICSLLTFDPAQR</Hsp_hseq>
      <Hsp_midline>+ S   + VA+K V+R KL           E  ++K I+HPH++ L D        YL++E+ + G+L   L ++  L                P E            + +Q+ SAL F  S ++   D+KP+NLLL        D K+              ++IADFG A      SL ET CGSP Y  PE++  +KY+  KAD+WS G ++F +            L L +K+KR   V   P +  I P+ + L+  ++  D  +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.9669</Hsp_bit-score>
      <Hsp_score>219</Hsp_score>
      <Hsp_evalue>2.78318e-19</Hsp_evalue>
      <Hsp_query-from>130</Hsp_query-from>
      <Hsp_query-to>558</Hsp_query-to>
      <Hsp_hit-from>372</Hsp_hit-from>
      <Hsp_hit-to>522</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>151</Hsp_align-len>
      <Hsp_qseq>SESVLMKLIEHPHVLKLYDVYENKKYLYL-VLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMA-----SLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFAL</Hsp_qseq>
      <Hsp_hseq>SEFCISSSLHHTNIVTTLDLFQDAKGEYCEVMEYCAGGDLFTLVVAAGKLEYMEADCFFKQLIRGVVYMHEMGVCHRDLKPENLLLTHDGVLKITDFGNSECFKMAWEKNIHLSGGVCGSSPYIAPEEYIKEEFDPRPVDIWACGVIYMAM</Hsp_hseq>
      <Hsp_midline>SE  +   + H +++   D++++ K  Y  V+E+ +GG+LF  +V  G+L   EA  FF+Q+I  + + H   +   DLKPENLLL     ++I DFG +     + +    L    CGS  Y  PE    E++D R  D+W+CGVI  A+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.0409</Hsp_bit-score>
      <Hsp_score>214</Hsp_score>
      <Hsp_evalue>1.73217e-18</Hsp_evalue>
      <Hsp_query-from>61</Hsp_query-from>
      <Hsp_query-to>648</Hsp_query-to>
      <Hsp_hit-from>1110</Hsp_hit-from>
      <Hsp_hit-to>1335</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>227</Hsp_align-len>
      <Hsp_qseq>VKLGIHSVTGRKVAVKIVNREKL---------------SESVLMKLIE---HPHVLKLYDVYENKKYLYLVLE-HVSGG--ELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSI--WDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVL------LEKVKRG--VFHMPHFIPPDCQALLRGMI</Hsp_qseq>
      <Hsp_hseq>VNLCIHKKNRYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKKPHENILRLLDFFEDDDYYYIETPVHGETGCIDLFDLIEFKTNMTEFEAKLIFKQVVAGIKHLHDQGIVHRDIKDENVIVDSKGFVKIIDFGSAAY-VKSGPFDVFVGTIDYAAPEVLGGNPYEGQPQDIWAIGILLYTVVFKENPFYNIDEILEGDLKFNNAEEVSEDCIELIKSIL</Hsp_hseq>
      <Hsp_midline>V L IH      V +K++ +E++               SE  +M  +    H ++L+L D +E+  Y Y+    H   G  +LFD +  K  +T  EA+  F+Q+++ +   H   I   D+K EN+++D K  ++I DFG A+  V     +   G+  YA PEV+ G  Y+G+  D+W+ G++L+ ++        ++++  G   F+    +  DC  L++ ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.5001</Hsp_bit-score>
      <Hsp_score>210</Hsp_score>
      <Hsp_evalue>4.57975e-18</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>642</Hsp_hit-from>
      <Hsp_hit-to>808</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>170</Hsp_align-len>
      <Hsp_qseq>TGRKVAVKIVNREK-------LSESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMASLQVGDSLLE--TSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL</Hsp_qseq>
      <Hsp_hseq>TNVSVAIKQMNLEKQPKKELIINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTD-VVTHCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCA-QINELNLKRTTMVGTPYWMAPEVVSRKEY-GPKVDIWSLGIMIIEMI</Hsp_hseq>
      <Hsp_midline>T   VA+K +N EK       ++E ++MK  +HP+++   D Y  K  L++++E++ GG L D +V    LT  +     R+ +S L+F HS  +   D+K +N+LL  + +I++ DFG  + Q+ +  L+  T  G+P++  PEV+  ++Y G K D+WS G+++  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.1889</Hsp_bit-score>
      <Hsp_score>204</Hsp_score>
      <Hsp_evalue>2.69428e-17</Hsp_evalue>
      <Hsp_query-from>91</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>50</Hsp_hit-from>
      <Hsp_hit-to>224</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>177</Hsp_align-len>
      <Hsp_qseq>RKVAVKIVNREKLSESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSI--WDLKPENLLLDEKNNIRIADFGMASL----QVGDSLLETS--------------CGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL</Hsp_qseq>
      <Hsp_hseq>KEAKVKYVTIEKNTMNLLAQK-HHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQC-GYGSDIWALGCMIYQFV</Hsp_hseq>
      <Hsp_midline>++  VK V  EK + ++L +   H  ++KLY  + +++ LY VL+   GGEL   L K G       R F  Q+I AL+F HSH I   DLKPEN+LLD    + I DFG A+       GDS    S               G+  Y  PE++   +  G  +D+W+ G +++  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.4925</Hsp_bit-score>
      <Hsp_score>197</Hsp_score>
      <Hsp_evalue>2.96819e-17</Hsp_evalue>
      <Hsp_query-from>58</Hsp_query-from>
      <Hsp_query-to>567</Hsp_query-to>
      <Hsp_hit-from>20</Hsp_hit-from>
      <Hsp_hit-to>200</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>182</Hsp_align-len>
      <Hsp_qseq>LVKLGIHSVTGRKVAVKIVNREKLSESVLMKLI---------EHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMA-SLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVL</Hsp_qseq>
      <Hsp_hseq>VVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNVIELIDIFMAYDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVI-FAELML</Hsp_hseq>
      <Hsp_midline>+V LG    TGRK+A+K +   +  + + M  I         +HP+V++L D++     L LVLE +          K    TP + + +    +  +  CH + I   DLKP NLL      I++ADFG+A ++     +L ++  +  Y  PE++ G K+     D+WS GVI FA L+L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YKL168C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:131288:133462:-1 gene:YKL168C transcript:YKL168C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KKQ8 description:Putative serine/threonine protein kinase with unknown cellular role; KKQ8 has a paralog, HAL5, that arose from the whole genome duplication [Source:SGD;Acc:S000001651]</Hit_def>
  <Hit_accession>YKL168C</Hit_accession>
  <Hit_len>724</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.8037</Hsp_bit-score>
      <Hsp_score>203</Hsp_score>
      <Hsp_evalue>3.17935e-17</Hsp_evalue>
      <Hsp_query-from>163</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>494</Hsp_hit-from>
      <Hsp_hit-to>639</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>146</Hsp_align-len>
      <Hsp_qseq>PHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKK----GRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMASL--QVGDSLLETSCG----SPHYACPEVIRGEKYDGRKADVWSCGVILFALLV</Hsp_qseq>
      <Hsp_hseq>PNILNVFDILEDSSSFIEVMEFCPAGDLYGMLVGKSKLKGRLHPLEADCFMKQLLHGVKFMHDHGIAHCDLKPENILFYPHGLLKICDFGTSSVFQTAWERRVHAQKGIIGSEPYVAPEEFVDGEYYDPRLIDCWSCGVVYITMIL</Hsp_hseq>
      <Hsp_midline>P++L ++D+ E+      V+E    G+L+  LV K    GRL P EA  F +Q++  + F H H I   DLKPEN+L      ++I DFG +S+     +  +    G     P+ A  E + GE YD R  D WSCGV+   +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.4185</Hsp_bit-score>
      <Hsp_score>202</Hsp_score>
      <Hsp_evalue>4.74542e-17</Hsp_evalue>
      <Hsp_query-from>61</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>139</Hsp_hit-from>
      <Hsp_hit-to>332</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>196</Hsp_align-len>
      <Hsp_qseq>VKLGIHSVTGRKVAVKIVNREKL-----------SESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPH---------------YACPEVIRGEKYDGRKADVWSCGVILFALLV</Hsp_qseq>
      <Hsp_hseq>VVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQKLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKI-LPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELL-NDNYTDSRCDIWAFGCILYQMLA</Hsp_hseq>
      <Hsp_midline>V L     +G+K AVK++++E L            +  L KL     + KL+  ++++  LY +LE+   G+    + K G L    AR +  QII A+D  H+  I   D+KPEN+LLD+   +++ DFG A + + +    T+ G P+               Y  PE++  + Y   + D+W+ G IL+ +L </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.4185</Hsp_bit-score>
      <Hsp_score>202</Hsp_score>
      <Hsp_evalue>5.6534e-17</Hsp_evalue>
      <Hsp_query-from>61</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>855</Hsp_hit-from>
      <Hsp_hit-to>1087</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>234</Hsp_align-len>
      <Hsp_qseq>VKLGIHSVTGRKVAVKIVNREKL---------------SESVLMKLIE---HPHVLKLYDVYENKKYLYL---VLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVL------LEKVKRGV--FHMPHFIPPDCQALLRGMIEVDAEKR</Hsp_qseq>
      <Hsp_hseq>VNLCIHNREHYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKNSQENILKLLDFFEDDDYYYIETPVHGETGSIDLFDVIEFKKDMVEHEAKLVFKQVVASIKHLHDQGIVHRDIKDENVIVDSHGFVKLIDFGSAAY-IKSGPFDVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLYTIIYKENPYYNIDEILEGELRFDKSEHVSEECISLIKRILTREVDKR</Hsp_hseq>
      <Hsp_midline>V L IH+     V +K++ +E++               SE  +M  +      ++LKL D +E+  Y Y+   V       +LFD +  K  +   EA+  F+Q+++++   H   I   D+K EN+++D    +++ DFG A+  +     +   G+  YA PEV+ G  Y G+  D+W+ GV+L+ ++        ++++  G   F     +  +C +L++ ++  + +KR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.0333</Hsp_bit-score>
      <Hsp_score>201</Hsp_score>
      <Hsp_evalue>6.02402e-17</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>346</Hsp_hit-from>
      <Hsp_hit-to>536</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>192</Hsp_align-len>
      <Hsp_qseq>TGRKVAVKIVNREK----------LSESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYL-VKKGRLTPKEARRFF-RQIISALDFCH--SHSIWDLKPENLLLDEKNNIRIADFGMASLQVG--------DSLLETS-----------CGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL</Hsp_qseq>
      <Hsp_hseq>TNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTA-AVDWWTLGILIYEML</Hsp_hseq>
      <Hsp_midline>T +  A+K++N+ +          L+E  ++   +HP ++ LY  ++ K YLYL +E+  GGE F  L  +K +   +E  +F+  ++++AL++ H       DLKPEN+LL +  ++ ++DF ++    G         + L+T             G+  Y  PEVIRG  +     D W+ G++++ +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.7221</Hsp_bit-score>
      <Hsp_score>195</Hsp_score>
      <Hsp_evalue>6.29164e-17</Hsp_evalue>
      <Hsp_query-from>70</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>24</Hsp_hit-from>
      <Hsp_hit-to>204</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>182</Hsp_align-len>
      <Hsp_qseq>GIHSVTGRKVAVKIVNREK--------LSESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKG-RLTPKE-----ARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMA-SLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLV</Hsp_qseq>
      <Hsp_hseq>GLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDN-DLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMIT</Hsp_hseq>
      <Hsp_midline>G++  TG  VA+K V  +         + E  LMK ++H ++++LYDV   +  L LV E +   +L  Y+  +    TP+       + F  Q++  L FCH + I   DLKP+NLL++++  +++ DFG+A +  +  +   +   +  Y  P+V+ G +      D+WSCG IL  ++ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.0333</Hsp_bit-score>
      <Hsp_score>201</Hsp_score>
      <Hsp_evalue>6.61313e-17</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>846</Hsp_hit-from>
      <Hsp_hit-to>1019</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>176</Hsp_align-len>
      <Hsp_qseq>TGRKVAVKIVNREKLSES-------------VLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSI--WDLKPENLLLDEKNNIRIADFGMASLQVG-DSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLV</Hsp_qseq>
      <Hsp_hseq>TDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLM-WHVQNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEY-TKAVDWWAFGVLLYQMLL</Hsp_hseq>
      <Hsp_midline>T R  A+K++ ++ + ++             +L    +HP +  LY  ++ +  +Y  +E + GG+L  + V+  RL+ + A+ +  +++ AL + H + +   DLK EN+LL  + +I+IAD+G+   ++   +   T CG+P +  PE+++ ++Y  +  D W+ GV+L+ +L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.337</Hsp_bit-score>
      <Hsp_score>194</Hsp_score>
      <Hsp_evalue>1.28336e-16</Hsp_evalue>
      <Hsp_query-from>88</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>25</Hsp_hit-from>
      <Hsp_hit-to>216</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>194</Hsp_align-len>
      <Hsp_qseq>GRKVAVKIVNREKLSESVL------MKLIE----HPHVLKLYDVYENKKYLYLVLEHVSGGELFDYL-VKKGRLTPK-------EARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEK----------------YDGRKADVWSCGVILFALL</Hsp_qseq>
      <Hsp_hseq>NRYVALKITPKYKTSEANMKNEYDVMKILSSCNPHPNICSMLDFYTDDSYYIMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQIDMQKIIKQLCSAISFAHSLGIAHRDIKPENILLTINGDIKLADWGHA-IQSPKS-NDFQIGTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLM</Hsp_hseq>
      <Hsp_midline> R VA+KI  + K SE+ +      MK++     HP++  + D Y +  Y  +VLE+   G+L+D+L + K + +P        + ++  +Q+ SA+ F HS  I   D+KPEN+LL    +I++AD+G A +Q   S  +   G+ +Y  PE   G                  Y+  +AD WS G  +F L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.7221</Hsp_bit-score>
      <Hsp_score>195</Hsp_score>
      <Hsp_evalue>2.11029e-16</Hsp_evalue>
      <Hsp_query-from>58</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>154</Hsp_hit-from>
      <Hsp_hit-to>402</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>55</Hsp_gaps>
      <Hsp_align-len>254</Hsp_align-len>
      <Hsp_qseq>LVKLGIHSVTGRKVAVKI--VNREK-LSESVLMKLI--EHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSI--WDLKPENLLLD-----------EKNN-------------IRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL------------VLLEKVKRGVFHMPHFIPPDCQALLRG-------MIEVDAEKR</Hsp_qseq>
      <Hsp_hseq>IIKKGISSDAILKGNDRIQGSSRKKVLNEVAIHKLVSKNNPHCTKFIAFQESANYYYLVTELVTGGEIFDRIVQLTCFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAK-KLRNNTAKTPCGTIEYVASEVFTSKRY-SMKVDMWSIGCVLFTLLCGYPPFYEKNEKTLLKKISRGDY---EFLAPWWDNISSGAKNAVTHLLEVDPNKR</Hsp_hseq>
      <Hsp_midline>++K GI S    K   +I   +R+K L+E  + KL+   +PH  K     E+  Y YLV E V+GGE+FD +V+    +   AR    Q+  A+   H   I   D+KPENLL +           +K +             +++ DFG+A  ++ ++  +T CG+  Y   EV   ++Y   K D+WS G +LF LL             LL+K+ RG +    F+ P    +  G       ++EVD  KR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.4925</Hsp_bit-score>
      <Hsp_score>197</Hsp_score>
      <Hsp_evalue>2.32044e-16</Hsp_evalue>
      <Hsp_query-from>58</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>36</Hsp_hit-from>
      <Hsp_hit-to>215</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>182</Hsp_align-len>
      <Hsp_qseq>LVKLGIHSVTGRKVAVKIVNREKLSESV---------LMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSI--WDLKPENLLLDEKNNIRIADFGMASLQVGDSLL--ETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLV</Hsp_qseq>
      <Hsp_hseq>VVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRS-LLRPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAA-QVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIAT</Hsp_hseq>
      <Hsp_midline>+V  G +  TGR  A+K++N +  S+ V         L  L +  ++ + Y  Y     L++++EH +GG L   L++ G++  K      R+++ AL   H  ++   D+K  N+L+  + N+++ DFG+A+ QV  + L  +T  G+P++  PEVI    Y   K D+WS G+  + +  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.337</Hsp_bit-score>
      <Hsp_score>194</Hsp_score>
      <Hsp_evalue>3.61499e-16</Hsp_evalue>
      <Hsp_query-from>61</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>64</Hsp_hit-from>
      <Hsp_hit-to>270</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>207</Hsp_align-len>
      <Hsp_qseq>VKLGIHSVTGRKVAVKIVNR-EKLS---------------ESVLMKLIEHPHVLKLYDVYENKKY--LYLVLEHVSGG--------ELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMA-SLQVGDSLLETS---------CGSPHYACPEVIRGEK-YDGRKA-DVWSCGVILFALL</Hsp_qseq>
      <Hsp_hseq>VKLARDLGTGALVAIKILNRFEKRSGYSLQLKVENPRVNQEIEVMKRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLL</Hsp_hseq>
      <Hsp_midline>VKL     TG  VA+KI+NR EK S               E  +MK   H +V++LY++  + +   +YLVLE+ S G        ++    V    LT +++R+    ++S L++ HS  I   D+KP NLL+     ++I+DFG+A S   G + +++S          G+P +  PE+   EK Y    A D+WS GV ++ LL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.5666</Hsp_bit-score>
      <Hsp_score>192</Hsp_score>
      <Hsp_evalue>8.74795e-16</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>518</Hsp_hit-from>
      <Hsp_hit-to>711</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>196</Hsp_align-len>
      <Hsp_qseq>TGRKVAVKIVNREK----------LSESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYL-VKKGR-LTPKEARRFFRQIISALDFCH--SHSIWDLKPENLLLDEKNNIRIADFGMASLQVGDS------------LLETS-----------CGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL</Hsp_qseq>
      <Hsp_hseq>TNRVYALKVLSKDEMIKRNKIKRVLTEQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDFDL-SIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRGNGHTA-AVDWWTLGILIYEML</Hsp_hseq>
      <Hsp_midline>T R  A+K++++++          L+E  ++    HP ++ LY  ++++ YLYL +E+  GGE F  L  +K + +   +AR +  ++ +AL++ H       DLKPEN+LL +  +I ++DF + S+Q  DS            L++T             G+  Y  PEVIRG  +     D W+ G++++ +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.4034</Hsp_bit-score>
      <Hsp_score>176</Hsp_score>
      <Hsp_evalue>7.32747e-14</Hsp_evalue>
      <Hsp_query-from>16</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>560</Hsp_hit-from>
      <Hsp_hit-to>762</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>204</Hsp_align-len>
      <Hsp_qseq>IWMPSSDFIVTPSRLVKLGIHSV----TGRKVAVK--IVNREK-----LSESVLMKLIEHPHVLKLYDVY-ENKKYLYLVLEHVSGGELFDYLVKK-------GRLTPKEARRFFRQIISALDFCHSHSI--WDLKPENLLLDEKNNIRIADFGM-ASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL</Hsp_qseq>
      <Hsp_hseq>VYLAERTHIPTESNMIELINNDIDEPHVGDKVAIKQMVLSKQPRKELIVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYD-EKIDVWSLGIMTIEML</Hsp_hseq>
      <Hsp_midline>+++     I T S +++L  + +     G KVA+K  +++++      ++E ++MK   H +++   + Y      L++V+E + GG L D +            LT  +     R+    L F H   I   D+K +N+LLD +  ++I DFG  A L    S   T  G+P++  PEV++  +YD  K DVWS G++   +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>8.78483e-14</Hsp_evalue>
      <Hsp_query-from>214</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>305</Hsp_hit-from>
      <Hsp_hit-to>439</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>135</Hsp_align-len>
      <Hsp_qseq>LVLEHVSGGELFD-YLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLD----------------EKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL</Hsp_qseq>
      <Hsp_hseq>MIMSYCPAGDLLAAVMARNGRLEAWLIQRIFTEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLCKKIENNEMCTARCGSEDYVSPEILMGVPYDGHLSDTWALGVILYSLF</Hsp_hseq>
      <Hsp_midline>+++ +   G+L    + + GRL     +R F +++ A+ + H +SI   DLK EN+LL                 ++N I +ADFG+      + +    CGS  Y  PE++ G  YDG  +D W+ GVIL++L </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>1.21763e-13</Hsp_evalue>
      <Hsp_query-from>100</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>204</Hsp_hit-from>
      <Hsp_hit-to>410</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>64</Hsp_gaps>
      <Hsp_align-len>213</Hsp_align-len>
      <Hsp_qseq>AVKIVNREKLSESVLMKLIEHPHVL---------------KLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCH--SHSIWDLKPENLLLDEKNNIRIADFGMASLQVGDSLLE-----------------------------------------TSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLV</Hsp_qseq>
      <Hsp_hseq>ALKILNKK-----LLFKLNETKHVLTERDILTTTRSEWLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINTRCLKSGHARFYISEMFCAVNALHDLGYTHRDLKPENFLIDAKGHIKLTDFGLAAGTISNERIESMKIRLEKIKDLEFPAFTEKSIEDRRKMYNQLREKEINYANSMVGSPDYMALEVLEGKKYDF-TVDYWSLGCMLFESLV</Hsp_hseq>
      <Hsp_midline>A+KI+N++     +L KL E  HVL               KL   +++ + LYL +E V GG+    L+    L    AR +  ++  A++  H   ++  DLKPEN L+D K +I++ DFG+A+  + +  +E                                         +  GSP Y   EV+ G+KYD    D WS G +LF  LV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.8626</Hsp_bit-score>
      <Hsp_score>172</Hsp_score>
      <Hsp_evalue>1.44866e-13</Hsp_evalue>
      <Hsp_query-from>100</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>197</Hsp_hit-from>
      <Hsp_hit-to>380</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>186</Hsp_align-len>
      <Hsp_qseq>AVKIV----NREKLSESVLMKLIEHPHVLKLYDVY-ENKKYLYLVLEHVSGGELFDYLVKKGRLTP---KEARRFFRQIISALDFCHSHSI--WDLKPENLLL---DEKNNIRIADFGMA-SLQVGDSLLETSCGSPHYACPEV-----------------IRGEKYDGRKADVWSCGVILFALLV</Hsp_qseq>
      <Hsp_hseq>AVKIIKLKPNKFDKEARILLRL-DHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDS-KCDLWSLGVITHIMLT</Hsp_hseq>
      <Hsp_midline>AVKI+    N+      +L++L +HP+++K+Y  + +   +LY+  + + GG+LF YL K   LT     E+     QI+ AL++ H   I   DLK +N+LL   +    I +ADFG+A  L      + T  G+P Y  PEV                 +    YD  K D+WS GVI   +L </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>1.85985e-13</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>558</Hsp_query-to>
      <Hsp_hit-from>235</Hsp_hit-from>
      <Hsp_hit-to>408</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>176</Hsp_align-len>
      <Hsp_qseq>TGRKV-AVKIVN---------REKLSESVLMKLIEHPHVLKLYDVY--ENKKYLYLVLEHVSGGEL---FDYLVKKG-RLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFAL</Hsp_qseq>
      <Hsp_hseq>NGKKVFALKTINTMNTDPEYQKQIFRELQFNKSFKSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFGVSGEAV-NSLAMTFTGTSFYMAPERIQGQPY-SVTCDVWSLGLTLLEV</Hsp_hseq>
      <Hsp_midline> G+KV A+K +N         ++   E    K  +  ++++ Y ++  E    +Y+ +E++ G  L   +  L+K+G R++ +   +    ++  L + H   +   D+KP+N+LL+EK  I++ DFG++   V +SL  T  G+  Y  PE I+G+ Y     DVWS G+ L  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YFL033C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:69115:74427:-1 gene:YFL033C transcript:YFL033C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM15 description:Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase [Source:SGD;Acc:S000001861]</Hit_def>
  <Hit_accession>YFL033C</Hit_accession>
  <Hit_len>1770</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.8626</Hsp_bit-score>
      <Hsp_score>172</Hsp_score>
      <Hsp_evalue>2.73367e-13</Hsp_evalue>
      <Hsp_query-from>61</Hsp_query-from>
      <Hsp_query-to>420</Hsp_query-to>
      <Hsp_hit-from>808</Hsp_hit-from>
      <Hsp_hit-to>940</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>133</Hsp_align-len>
      <Hsp_qseq>VKLGIHSVTGRKVAVKIVNRE-----------KLSESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSI--WDLKPENLLLDEKNNIRIADFGMA</Hsp_qseq>
      <Hsp_hseq>VYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDKPYVARLFASFQNKDNLFLVMEYLPGGDLATLIKMMGYLPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLIDNAGHVKLTDFGLS</Hsp_hseq>
      <Hsp_midline>V L    +TG   A+K++ +            K   +++M   + P+V +L+  ++NK  L+LV+E++ GG+L   +   G L  + A+++  +I+  ++  H + I   DLKPENLL+D   ++++ DFG++</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>47.3654</Hsp_bit-score>
      <Hsp_score>111</Hsp_score>
      <Hsp_evalue>4.6874e-06</Hsp_evalue>
      <Hsp_query-from>460</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>1149</Hsp_hit-from>
      <Hsp_hit-to>1239</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>41</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>91</Hsp_align-len>
      <Hsp_qseq>GSPHYACPEVIRGEKYDGRKADVWSCGVILFALLV------------LLEKVKRGVFHMPH---------FIPPDCQALLRGMIEVDAEKR</Hsp_qseq>
      <Hsp_hseq>GTPDYLAPETIEGKGEDNKQCDWWSVGCIFFELLLGYPPFHAETPDAVFKKILSGVIQWPEFKNEEEEREFLTPEAKDLIEKLLVVDPAKR</Hsp_hseq>
      <Hsp_midline>G+P Y  PE I G+  D ++ D WS G I F LL+            + +K+  GV   P          F+ P+ + L+  ++ VD  KR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YPR111W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:747306:749000:1 gene:YPR111W transcript:YPR111W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF20 description:Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006315]</Hit_def>
  <Hit_accession>YPR111W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>3.05009e-13</Hsp_evalue>
      <Hsp_query-from>100</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>196</Hsp_hit-from>
      <Hsp_hit-to>402</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>64</Hsp_gaps>
      <Hsp_align-len>213</Hsp_align-len>
      <Hsp_qseq>AVKIVNREKLSESVLMKLIEHPHVL---------------KLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHS--HSIWDLKPENLLLDEKNNIRIADFGMASLQVGDSLLE-----------------------------------------TSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLV</Hsp_qseq>
      <Hsp_hseq>ALKILNKK-----LLFKLNETNHVLTERDILTTTRSDWLVKLLYAFQDPESLYLAMEFVPGGDFRTLLINTRILKSGHARFYISEMFCAVNALHELGYTHRDLKPENFLIDATGHIKLTDFGLAAGTVSNERIESMKIRLEEVKNLEFPAFTERSIEDRRKIYHNMRKTEINYANSMVGSPDYMALEVLEGKKYDF-TVDYWSLGCMLFESLV</Hsp_hseq>
      <Hsp_midline>A+KI+N++     +L KL E  HVL               KL   +++ + LYL +E V GG+    L+    L    AR +  ++  A++  H   ++  DLKPEN L+D   +I++ DFG+A+  V +  +E                                         +  GSP Y   EV+ G+KYD    D WS G +LF  LV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YDR247W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:956013:957398:1 gene:YDR247W transcript:YDR247W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VHS1 description:Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; VHS1 has a paralog, SKS1, that arose from the whole genome duplication [Source:SGD;Acc:S000002655]</Hit_def>
  <Hit_accession>YDR247W</Hit_accession>
  <Hit_len>461</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>3.22141e-13</Hsp_evalue>
      <Hsp_query-from>136</Hsp_query-from>
      <Hsp_query-to>567</Hsp_query-to>
      <Hsp_hit-from>110</Hsp_hit-from>
      <Hsp_hit-to>270</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>167</Hsp_align-len>
      <Hsp_qseq>SVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKE--ARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSC-GSPHYACPEVIRGEKYDGR------------------KADVWSCGVILFALLVL</Hsp_qseq>
      <Hsp_hseq>SLHLRVHHHKNIVTIHEVLQSAVCTFIVMDYYPT-DLFTSIVDNRHFVTNGLLVKKVFLQICSALNYCHEHGIYHCDIKPENLLLDTEDNVFLCDFGLSTTST--YIKPNVCIGSSYYMPPERI---SFDGRVSSSKSGGHKLGKVCPSCNGDLWSLGIILINLTCI</Hsp_hseq>
      <Hsp_midline>S+ +++  H +++ +++V ++    ++V+++    +LF  +V            ++ F QI SAL++CH H I+  D+KPENLLLD ++N+ + DFG+++      +    C GS +Y  PE I    +DGR                    D+WS G+IL  L  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YJL165C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:106894:109461:-1 gene:YJL165C transcript:YJL165C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HAL5 description:Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters; HAL5 has a paralog, KKQ8, that arose from the whole genome duplication [Source:SGD;Acc:S000003701]</Hit_def>
  <Hit_accession>YJL165C</Hit_accession>
  <Hit_len>855</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>3.39105e-13</Hsp_evalue>
      <Hsp_query-from>163</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>601</Hsp_hit-from>
      <Hsp_hit-to>764</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>164</Hsp_align-len>
      <Hsp_qseq>PHVLKLYDVYENKKYLYLVLEHVSGGELFDYL-------------------VKKGR---LTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMASL-----QVGDSLLETSCGSPHYACPE-VIRGEKYDGRKADVWSCGVILFALLV</Hsp_qseq>
      <Hsp_hseq>PNILKILDLMEYSNSFVEVMEFCASGDLYSLLTRNNISNESNNGSSRLIQTVKEGSGSPLHPLEADCFMKQLLNGVQYMHDHGIAHCDLKPENILFQPNGLLKICDFGTSSVFQTAWEKHVHFQSGAMGSEPYVAPEEFIRDAEYDPRLVDCWSCGIVYCTMVM</Hsp_hseq>
      <Hsp_midline>P++LK+ D+ E       V+E  + G+L+  L                   VK+G    L P EA  F +Q+++ + + H H I   DLKPEN+L      ++I DFG +S+     +        + GS  Y  PE  IR  +YD R  D WSCG++   +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>3.92083e-13</Hsp_evalue>
      <Hsp_query-from>193</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>779</Hsp_hit-from>
      <Hsp_hit-to>919</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>ENKKYLYLVLEHVSGGELFDYLVKKGRLTPK--EARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMA---------------SLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL</Hsp_qseq>
      <Hsp_hseq>KKKSTLFIQMEYCENRTLYD-LIHSENLNQQRDEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNVKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVLDGTGHYNEKIDMYSLGIIFFEMI</Hsp_hseq>
      <Hsp_midline>+ K  L++ +E+     L+D L+    L  +  E  R FRQI+ AL + HS  I   DLKP N+ +DE  N++I DFG+A               +L      L ++ G+  Y   EV+ G  +   K D++S G+I F ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.3218</Hsp_bit-score>
      <Hsp_score>168</Hsp_score>
      <Hsp_evalue>5.53821e-13</Hsp_evalue>
      <Hsp_query-from>55</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>389</Hsp_hit-from>
      <Hsp_hit-to>576</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>189</Hsp_align-len>
      <Hsp_qseq>RLVKLGIHSVTGRKVAVKIVNREK-------LSESVLMKLIEHPHVLKLYDVYE-NKKYLYLVLEHVSGGELFDYLVKKGR---------LTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGM-ASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL</Hsp_qseq>
      <Hsp_hseq>RFLKSHCHRVVGERVAIKQIRLSEQPKKQLIMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYD-EKVDVWSLGIMLIEMI</Hsp_hseq>
      <Hsp_midline>R +K   H V G +VA+K +   +       ++E ++M      +++   + Y  + + L++++E++ GG L D L    R         L   +     ++    L F H+  I   D+K +N+LL+ +  ++I DFG    L    S   T  G+P++  PE++  + YD  K DVWS G++L  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.3218</Hsp_bit-score>
      <Hsp_score>168</Hsp_score>
      <Hsp_evalue>5.69757e-13</Hsp_evalue>
      <Hsp_query-from>94</Hsp_query-from>
      <Hsp_query-to>594</Hsp_query-to>
      <Hsp_hit-from>222</Hsp_hit-from>
      <Hsp_hit-to>437</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>53</Hsp_gaps>
      <Hsp_align-len>218</Hsp_align-len>
      <Hsp_qseq>KVAVKIVNREK-LSESVLMKLIEH--PHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSI--WDLKPENLLLD----------------------------------EKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL------------VLLEKVKRGVF</Hsp_qseq>
      <Hsp_hseq>KDSTKTSSRDQVLKEVALHKTVSAGCSQIVAFIDFQETDSYYYIIQELLTGGEIFGEIVRLTYFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGL-SKQIFSKNTKTPCGTVGYTAPEVVKDEHY-SMKVDMWGIGCVLYTMLCGFPPFYDEKIDTLTEKISRGEY</Hsp_hseq>
      <Hsp_midline>K + K  +R++ L E  L K +      ++   D  E   Y Y++ E ++GGE+F  +V+    +   +R   +Q+  A+   HS  +   D+KPENLL +                                      +++ADFG+ S Q+     +T CG+  Y  PEV++ E Y   K D+W  G +L+ +L             L EK+ RG +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>7.67507e-13</Hsp_evalue>
      <Hsp_query-from>91</Hsp_query-from>
      <Hsp_query-to>549</Hsp_query-to>
      <Hsp_hit-from>35</Hsp_hit-from>
      <Hsp_hit-to>202</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>168</Hsp_align-len>
      <Hsp_qseq>RKVAVKIVNREKLSESV---------LMKLIEHPHVLKLYD-VYENKKYLYLVLEHVSGG--ELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMA-SLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVIL</Hsp_qseq>
      <Hsp_hseq>RVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIF</Hsp_hseq>
      <Hsp_midline>R VA+K +  E   E V         L+K ++  ++++LYD V+ +   LYLV E +        + + K   L     ++F  Q+   + +CHSH I   DLKP+NLL+++  N+++ DFG+A +  V          +  Y  PEV+ G K      D WS G I </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>9.82208e-13</Hsp_evalue>
      <Hsp_query-from>79</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>113</Hsp_hit-from>
      <Hsp_hit-to>283</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>179</Hsp_align-len>
      <Hsp_qseq>SVTGRKVAVKIVNR---EKLSE-SVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEAR---RFFRQIISALDFCHSHSIW--DLKPENLLLDEKN-NIRIADFGMASLQVGDSLLETSCGSPHYACPEVI--------RGEKYDGRKADVWSCGVILFALL</Hsp_qseq>
      <Hsp_hseq>SLISSKVKSRLSNNICLEAMYEVDIQTKIGRHQNIAALLDFFDS----YIIMEYCSGGDLYEAI--KADAVPKKTKSITHIITQIMDAIEYVHNKGIYHRDIKPENILISGIDWTIKLTDWGLAT--TDKTSMDRNVGSERYMSPELFDSNLDIKERKEPYDCAKVDLWAMGIVFLNIV</Hsp_hseq>
      <Hsp_midline>S+   KV  ++ N    E + E  +  K+  H ++  L D +++    Y+++E+ SGG+L++ +  K    PK+ +       QI+ A+++ H+  I+  D+KPEN+L+   +  I++ D+G+A+     + ++ + GS  Y  PE+         R E YD  K D+W+ G++   ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.5514</Hsp_bit-score>
      <Hsp_score>166</Hsp_score>
      <Hsp_evalue>1.39238e-12</Hsp_evalue>
      <Hsp_query-from>61</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>1189</Hsp_hit-from>
      <Hsp_hit-to>1374</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>187</Hsp_align-len>
      <Hsp_qseq>VKLGIHSVTGRKVAVKIVNREKLS---ESVL------------MKLIEHPHVLKLYDVYENKKYLY-LVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMA--SLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL</Hsp_qseq>
      <Hsp_hseq>VYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQ-YLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMF</Hsp_hseq>
      <Hsp_midline>V L ++  TG  +AVK V   K S   E++L            +K ++H ++++ Y  +ENK  +Y L LE+V+GG +   +   GR      +    Q++  L + HS  I   D+K +NLLLD+    +I+DFG++  S  +  +   T  G+  +  PE++  ++    K D+WS G I+  + </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>2.68399e-12</Hsp_evalue>
      <Hsp_query-from>58</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>38</Hsp_hit-from>
      <Hsp_hit-to>213</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>179</Hsp_align-len>
      <Hsp_qseq>LVKLGIHSVTGRKVAVKIV---NREKL----SESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGR-LTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLV</Hsp_qseq>
      <Hsp_hseq>VVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSAL--TLAGTLNWMAPEIL-GNRGASTLSDIWSLGATVVEMLT</Hsp_hseq>
      <Hsp_midline>+V   I+  T + VA+K V   N E+L    +E  L+K + H +++K +        LY++LE+ + G L   + +    L+  E++ +  Q +  L + H   +   D+K  N+LL   N +++ADFG++++    +L  T  G+ ++  PE++ G +     +D+WS G  +  +L </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>2.94316e-12</Hsp_evalue>
      <Hsp_query-from>55</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>207</Hsp_hit-from>
      <Hsp_hit-to>375</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>RLVKLGIHSVTGRKVAVKIVNREKLSESVLMKLIEHPHVLKLYDVY-ENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL</Hsp_qseq>
      <Hsp_hseq>KLVALKKLRLQGEREGFPITS---IREIKLLQSFDHPNVSTIKEIMVESQKTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKMNSRADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELF</Hsp_hseq>
      <Hsp_midline>+LV L    + G +    I +   + E  L++  +HP+V  + ++  E++K +Y++ E+         L K+ +++  + +  F+Q++  +++ H + I   D+K  N+L+D + N++I DFG+A      +       +  Y  PE++ G    G + D+W CG +L  L </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>3.01702e-12</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>558</Hsp_query-to>
      <Hsp_hit-from>242</Hsp_hit-from>
      <Hsp_hit-to>415</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>177</Hsp_align-len>
      <Hsp_qseq>TGRKV-AVKIVN---------REKLSESVLMKLIEHPHVLKLYDVY--ENKKYLYLVLEHVSGGELFDYLVKK-----GRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFAL</Hsp_qseq>
      <Hsp_hseq>NGSKIFALKVINTLNTDPEYQKQIFRELQFNRSFQSEYIVRYYGMFTDDENSSIYIAMEYM-GGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVSGEAV-NSLATTFTGTSFYMAPERIQGQPY-SVTSDVWSLGLTILEV</Hsp_hseq>
      <Hsp_midline> G K+ A+K++N         ++   E    +  +  ++++ Y ++  +    +Y+ +E++ GG   D + K      GR++ K   +    ++  L + H   +   D+KP+N+LL+E   +++ DFG++   V +SL  T  G+  Y  PE I+G+ Y    +DVWS G+ +  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YNL183C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:293137:295509:-1 gene:YNL183C transcript:YNL183C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NPR1 description:Protein kinase; stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p; negatively regulates Ldb19p-mediated endocytosis through phosphorylation of Ldb19p, which prevents its association with the plasma membrane; Npr1p activity is negatively regulated via phosphorylation by the TOR complex; NPR1 has a paralog, PRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005127]</Hit_def>
  <Hit_accession>YNL183C</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>5.02494e-12</Hsp_evalue>
      <Hsp_query-from>130</Hsp_query-from>
      <Hsp_query-to>567</Hsp_query-to>
      <Hsp_hit-from>487</Hsp_hit-from>
      <Hsp_hit-to>636</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>154</Hsp_align-len>
      <Hsp_qseq>SESVLMKLIEHPHVLKLYD-VYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETS--CGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVL</Hsp_qseq>
      <Hsp_hseq>SEYCIGTTLNHPNIIETIEIVYENDRILQ-VMEYCEY-DLF-AIVMSNKMSYEEICCCFKQILTGVQYLHSIGLAHRDLKLDNCVINEKGIVKLIDFGAAVVFSYPFSKNLVEASGIVGSDPYLAPEVCIFAKYDPRPVDIWSSAII-FACMIL</Hsp_hseq>
      <Hsp_midline>SE  +   + HP++++  + VYEN + L  V+E+    +LF  +V   +++ +E    F+QI++ + + HS  +   DLK +N +++EK  +++ DFG A   S     +L+E S   GS  Y  PEV    KYD R  D+WS  +I FA ++L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>7.35531e-12</Hsp_evalue>
      <Hsp_query-from>64</Hsp_query-from>
      <Hsp_query-to>558</Hsp_query-to>
      <Hsp_hit-from>1064</Hsp_hit-from>
      <Hsp_hit-to>1245</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>187</Hsp_align-len>
      <Hsp_qseq>KLGIHSVTGRKVAVKIVNREKLSESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFR-QIISALDFCHSHSI--WDLKPENLLLDEKNNIRIADFGMASLQVG------------DSLLETSC-----GSPHYACPEVIRGEKYDGR--KADVWSCGVILFAL</Hsp_qseq>
      <Hsp_hseq>EIKIHDTTTMKKIFPLIKEEM----TVLEMLNHPNIVQYYGVEVHRDKVNIFMEYCEGGSLAS-LLDHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEM</Hsp_hseq>
      <Hsp_midline>++ IH  T  K    ++  E      +++++ HP++++ Y V  ++  + + +E+  GG L   L+  GR+  +   + +  +++  L + H   +   D+KPEN+LLD    I+  DFG A   VG            D  +ET       G+P Y  PE I G    G+    DVW+ G ++  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>1.67454e-11</Hsp_evalue>
      <Hsp_query-from>58</Hsp_query-from>
      <Hsp_query-to>609</Hsp_query-to>
      <Hsp_hit-from>36</Hsp_hit-from>
      <Hsp_hit-to>226</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>197</Hsp_align-len>
      <Hsp_qseq>LVKLGIHSVTGRKVAVK---------IVNREKLSESVLMKLIEHPHVLKLYDVYENK-KYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEV-IRGEKYDGRKADVWSCGVILFALLVLLEKVKRGVFHMPHF</Hsp_qseq>
      <Hsp_hseq>LVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLSPLEDIYFVTE-LQGTDLH-RLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQ--DPQMTGYVSTRYYRAPEIMLTWQKYD-VEVDIWSAGCI-FAEMIEGKPLFPGKDHVHQF</Hsp_hseq>
      <Hsp_midline>LV     ++T + VA+K         ++ +    E  L+K + H +++ L D++ +  + +Y V E + G +L   L++   L  +  + F  QI+  L + HS  +   DLKP N+L++E  +++I DFG+A +Q  D  +     + +Y  PE+ +  +KYD  + D+WS G I FA ++  + +  G  H+  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>2.21443e-11</Hsp_evalue>
      <Hsp_query-from>76</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>486</Hsp_hit-from>
      <Hsp_hit-to>700</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>217</Hsp_align-len>
      <Hsp_qseq>HSVTGRKVAVKIVNREKLSESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMAS----LQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVIL------------FALLVLLEKVKRGVF-HMPHFIPPDCQALLRGMIEVDAEKR</Hsp_qseq>
      <Hsp_hseq>HPKTNQNIHRKMVDALQ-HEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVK-QTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKIGTNTTPEIPSWATSEGKNFLRKAFELDYQYR</Hsp_hseq>
      <Hsp_midline>H  T + +  K+V+  +  E  L+K + H +++  Y   +    L + LE+V GG +   L   G         F RQI+  + + H  +I   D+K  N+L+D K  ++I DFG++     L    +   +  GS  +  PEV++ +     KAD+WS G ++            F+ +  + K+       +P +   + +  LR   E+D + R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>3.82193e-11</Hsp_evalue>
      <Hsp_query-from>73</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>56</Hsp_hit-from>
      <Hsp_hit-to>227</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>178</Hsp_align-len>
      <Hsp_qseq>IHSVTGRKVAVKIVNREKLSESVLMKLIEHPHVLKLYDV----YENKK----YLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMA-----SLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL</Hsp_qseq>
      <Hsp_hseq>IPNAFGNKLSCKRTLREL---KLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLY---EELMECDLSQIIRSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELL</Hsp_hseq>
      <Hsp_midline>I +  G K++ K   RE     +L  L  HP+++ L+D     Y N      YLY   E +   +L   +  + RL     + F  QI+ AL + HS ++   DLKP+NLL++    ++I +FG++     + +V D  ++    S  Y  PE++   +   +  D+WS G IL  LL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YIL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:287790:288908:-1 gene:YIL035C transcript:YIL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA1 description:Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000001297]</Hit_def>
  <Hit_accession>YIL035C</Hit_accession>
  <Hit_len>372</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>4.63543e-11</Hsp_evalue>
      <Hsp_query-from>160</Hsp_query-from>
      <Hsp_query-to>591</Hsp_query-to>
      <Hsp_hit-from>130</Hsp_hit-from>
      <Hsp_hit-to>275</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>149</Hsp_align-len>
      <Hsp_qseq>HPHVLKLYDVYEN--KKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKN-NIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVLLEKVKRGV</Hsp_qseq>
      <Hsp_hseq>HANIIHLFDIIKDPISKTPALVFEYVDN---VDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGT</Hsp_hseq>
      <Hsp_midline>H +++ L+D+ ++   K   LV E+V      D+ +   +LT  E R +  +++ ALD+CHS  I   D+KP N+++D KN  +R+ D+G+A     +        S  +  PE++   +      D+WS G +L +++   E    G </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>5.20628e-11</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>61</Hsp_hit-from>
      <Hsp_hit-to>235</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>176</Hsp_align-len>
      <Hsp_qseq>TGRKVAVKIV---NREKLSESVLMKLIEHPHVLKL-YDVYE----NKKYLYLVLEHVSGG---ELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW---DLKPENLLLD-EKNNIRIADFGMA-SLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLV</Hsp_qseq>
      <Hsp_hseq>TNEKVAIKKVLQDKRFKNRELEIMKMLSHINIIDLKYFFYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVSYIC-SRYYRAPELIFGATNYTNQIDIWSSGCVMAELLL</Hsp_hseq>
      <Hsp_midline>T  KVA+K V    R K  E  +MK++ H +++ L Y  YE    ++ YL L+LE++       L  ++ ++  ++  E + +  Q+  +L++ H  +     D+KP+NLL+D E  ++++ DFG A  L+  +  +   C S +Y  PE+I G      + D+WS G ++  LL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>9.52802e-11</Hsp_evalue>
      <Hsp_query-from>70</Hsp_query-from>
      <Hsp_query-to>630</Hsp_query-to>
      <Hsp_hit-from>35</Hsp_hit-from>
      <Hsp_hit-to>239</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>207</Hsp_align-len>
      <Hsp_qseq>GIHSVTGRKVAVKIVNREKLSESV--------LMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLT--PKEARRFF-RQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDG--RKADVWSCGVILFALLVLLEKVKRG-----VFHMPHFIPPDCQA</Hsp_qseq>
      <Hsp_hseq>AVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSD-LLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRDTFVGTPYWMAPEVVCCE-VDGYNEKADIWSLGITTYELLKGLPPLSKYDPMKVMTNLPKRKPPKLQG</Hsp_hseq>
      <Hsp_midline> +  VT   VA+K+VN E   E +         +  ++ P +            +++V+E+  GG   D L+K+  +   P+E   F   ++   L + H       D+K  N+LL+E+  +++ DFG++         +T  G+P++  PEV+  E  DG   KAD+WS G+  + LL  L  + +      + ++P   PP  Q </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>9.81204e-11</Hsp_evalue>
      <Hsp_query-from>61</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>147</Hsp_hit-from>
      <Hsp_hit-to>373</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>60</Hsp_gaps>
      <Hsp_align-len>227</Hsp_align-len>
      <Hsp_qseq>VKLGIHSVTGRKVAVKIVNR--------------EKLSES-------VLMKLIEHPHVLKLYDVYEN--KKYLYLVLEHVSGGELF----DYLVKKGR----LTPKEARRFFRQIISALDFCHSHSI--WDLKPENLLLDEKNNIRIADFGMA-----------SLQVGDSLLETSCGSPHYACPEVIRGE----KYDGRKA------------DVWSCGVILFALL</Hsp_qseq>
      <Hsp_hseq>VKLARDILSKQLVAIKIVDRHEKKQRKFFTFIKSSKISENDKIKREIAIMKKCHHKHVVQLIEVLDDLKSRKIYLVLEYCSRGEVKWCPPDCMESDAKGPSLLSFQETREILRGVVLGLEYLHYQGIIHRDIKPANLLISGDGTVKISDFGVSLAASSTNSSDSSESLDELELAKTVGTPAFFAPEMCLGEDAFTRYNLTKENLFRGSCISFMIDIWAVGVTLYCLL</Hsp_hseq>
      <Hsp_midline>VKL    ++ + VA+KIV+R               K+SE+        +MK   H HV++L +V ++   + +YLVLE+ S GE+     D +    +    L+ +E R   R ++  L++ H   I   D+KP NLL+     ++I+DFG++           S  + +  L  + G+P +  PE+  GE    +Y+  K             D+W+ GV L+ LL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>2.5618e-10</Hsp_evalue>
      <Hsp_query-from>70</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>30</Hsp_hit-from>
      <Hsp_hit-to>218</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>192</Hsp_align-len>
      <Hsp_qseq>GIHSVTGRKVAVKIVNR--------EKLSESVLMKLIEHPHVLKLYDV-----YENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMASLQVGDSLLETS------------CGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLV</Hsp_qseq>
      <Hsp_hseq>ATHKPTGEIVAIKKIEPFDKPLFALRTLREIKILKHFKHENIITIFNIQRPDSFENFNEVYIIQELMQTD--LHRVISTQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARI-IDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFL</Hsp_hseq>
      <Hsp_midline>  H  TG  VA+K +            L E  ++K  +H +++ ++++     +EN   +Y++ E +        ++    L+    + F  Q + A+   H  ++   DLKP NLL++   ++++ DFG+A + + +S  + S              +  Y  PEV+       R  DVWSCG IL  L +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YPL026C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:500675:502183:-1 gene:YPL026C transcript:YPL026C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKS1 description:Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway; SKS1 has a paralog, VHS1, that arose from the whole genome duplication [Source:SGD;Acc:S000005947]</Hit_def>
  <Hit_accession>YPL026C</Hit_accession>
  <Hit_len>502</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>3.71931e-10</Hsp_evalue>
      <Hsp_query-from>145</Hsp_query-from>
      <Hsp_query-to>558</Hsp_query-to>
      <Hsp_hit-from>114</Hsp_hit-from>
      <Hsp_hit-to>268</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>158</Hsp_align-len>
      <Hsp_qseq>MKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEA--RRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSC-GSPHYACPEVI--------RGEKYD-------GRKADVWSCGVILFAL</Hsp_qseq>
      <Hsp_hseq>LRVQSHGNIVKIHQVLESSIATFIVMDYY-DRDLFTSIVDDKHFVNHGILIKKVFLQLCSALDHCHRLGIYHCDIKPENVLLDRNDNAYLCDFGLST--KSKYLAPNVCVGSSYYMAPERILYCLNTTTNGIHVDECCSSLPTDTGDIWSLGIILINL</Hsp_hseq>
      <Hsp_midline>+++  H +++K++ V E+    ++V+++    +LF  +V            ++ F Q+ SALD CH   I+  D+KPEN+LLD  +N  + DFG+++      L    C GS +Y  PE I         G   D           D+WS G+IL  L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>71</Hit_num>
  <Hit_id>YDL214C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:74446:76545:-1 gene:YDL214C transcript:YDL214C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR2 description:Serine/threonine protein kinase; inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance; PRR2 has a paralog, NPR1, that arose from the whole genome duplication [Source:SGD;Acc:S000002373]</Hit_def>
  <Hit_accession>YDL214C</Hit_accession>
  <Hit_len>699</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>4.05325e-10</Hsp_evalue>
      <Hsp_query-from>127</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>409</Hsp_hit-from>
      <Hsp_hit-to>559</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>155</Hsp_align-len>
      <Hsp_qseq>LSESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCH----SHSIWDLKPENLLLDEKNNIRIADFGMASL---QVGDSLLETS--CGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLV</Hsp_qseq>
      <Hsp_hseq>ISEYCIASTLKNPNICETLEILYEKGKIFQILEYCEY-DLFS-LVMSEKMHYEEICCLFKQLINGVKYLHDIGLSHR--DLKLDNCVVTRRGILKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFYFNEYDPRALDVWSVGIIFFCMIT</Hsp_hseq>
      <Hsp_midline>+SE  +   +++P++ +  ++   K  ++ +LE+    +LF  LV   ++  +E    F+Q+I+ + + H    SH   DLK +N ++  +  +++ DFG +S+    +   ++E +   GS  Y  PEV    +YD R  DVWS G+I F ++ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>72</Hit_num>
  <Hit_id>YOR061W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:441534:442553:1 gene:YOR061W transcript:YOR061W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA2 description:Alpha&apos; catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000005587]</Hit_def>
  <Hit_accession>YOR061W</Hit_accession>
  <Hit_len>339</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>4.24088e-10</Hsp_evalue>
      <Hsp_query-from>82</Hsp_query-from>
      <Hsp_query-to>588</Hsp_query-to>
      <Hsp_hit-from>71</Hsp_hit-from>
      <Hsp_hit-to>246</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>179</Hsp_align-len>
      <Hsp_qseq>VTGRKVAVKIVNREKLSE-----SVLMKLIEHPHVLKLYDVYEN--KKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLD-EKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVLLEKVKRG</Hsp_qseq>
      <Hsp_hseq>VNNQKCVIKVLKPVKMKKIYRELKILTNLTGGPNVVGLYDIVQDADSKIPALIFEEIKNVD-FRTLYPTFKLP--DIQYYFTQLLIALDYCHSMGIMHRDVKPQNVMIDPTERKLRLIDWGLAEFYHPGVDYNVRVASRYHKGPELLVNLNQYDYSLDLWSVGCMLAAIVFKKEPFFKG</Hsp_hseq>
      <Hsp_midline>V  +K  +K++   K+ +      +L  L   P+V+ LYD+ ++   K   L+ E +   + F  L    +L   + + +F Q++ ALD+CHS  I   D+KP+N+++D  +  +R+ D+G+A              S ++  PE++          D+WS G +L A++   E   +G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>73</Hit_num>
  <Hit_id>YDL079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:312951:314748:-1 gene:YDL079C transcript:YDL079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRK1 description:Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication [Source:SGD;Acc:S000002237]</Hit_def>
  <Hit_accession>YDL079C</Hit_accession>
  <Hit_len>501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>5.0446e-10</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>186</Hsp_hit-from>
      <Hsp_hit-to>360</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>177</Hsp_align-len>
      <Hsp_qseq>TGRKVAVKIV---NREKLSESVLMKLIEHPHVLKL-YDVYENKK----YLYLVLEHVSGG---ELFDYLVKKGRLTPKEARRFFRQIISALDFCHS-----HSIWDLKPENLLLDEKN-NIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLV</Hsp_qseq>
      <Hsp_hseq>TNQKVAIKKVLQDRRYKNRELETMKMLCHPNTVGLQYYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNVPRICHR--DIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLL</Hsp_hseq>
      <Hsp_midline>T +KVA+K V    R K  E   MK++ HP+ + L Y  YE  +    YL LVL+++       L  ++  K ++   E + +  Q+  AL++ H+     H   D+KP+NLL+D    + +I DFG A     D    +   S +Y  PE++ G      + DVWS   ++  LL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>74</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>6.14098e-10</Hsp_evalue>
      <Hsp_query-from>109</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>231</Hsp_hit-from>
      <Hsp_hit-to>399</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>171</Hsp_align-len>
      <Hsp_qseq>IVNREKLSESVLMKLIEHPHVLKLYDVYENK---KYLYLVLEHVSGGEL------FDYLVKKGRLTPKEA-------RRFFRQIISALDFCHSHSIW---DLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLV</Hsp_qseq>
      <Hsp_hseq>IINQLVRELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGV-SKKLINSIADTFVGTSTYMSPERIQGNVY-SIKGDVWSLGLMIIELVT</Hsp_hseq>
      <Hsp_midline>I+N+     S++  +  H +++  Y  Y N+     + +++E+   G L      +   V++G ++ K+         +    +++ LD  +        D+KP N+L++ K  I++ DFG+ S ++ +S+ +T  G+  Y  PE I+G  Y   K DVWS G+++  L+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>75</Hit_num>
  <Hit_id>YMR291W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:852630:854390:1 gene:YMR291W transcript:YMR291W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TDA1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000004905]</Hit_def>
  <Hit_accession>YMR291W</Hit_accession>
  <Hit_len>586</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>2.25069e-09</Hsp_evalue>
      <Hsp_query-from>91</Hsp_query-from>
      <Hsp_query-to>624</Hsp_query-to>
      <Hsp_hit-from>90</Hsp_hit-from>
      <Hsp_hit-to>294</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>211</Hsp_align-len>
      <Hsp_qseq>RKVAVKIVNREKLSESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLT-PKEARRFFRQIISALDFCHSHSI--WDLKPENLLL------DEKN----------------NIRIADFGMASLQVGDSL--LETSCGSPHYACPEVIR----GEKYDGR--KADVWSCGVILFALLVLLEKVKRGVFHMPHFIPPDC</Hsp_qseq>
      <Hsp_hseq>RSISEKIRDMEKKNEHSLDIFEGHHHILQLFDYFETADNIVLITQLCQKGDLYEKIVENQCLDLETQVTSYCACLVSVLEFLHSQGIVHRDLKAENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLVLADFGLAAEYNTSKVNSLKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGCPVDIWALGVLTYFMAFG------YTPFDC</Hsp_hseq>
      <Hsp_midline>R ++ KI + EK +E  L     H H+L+L+D +E    + L+ +    G+L++ +V+   L    +   +   ++S L+F HS  I   DLK EN+L       +EKN                ++ +ADFG+A+      +  L+   G+  Y  PE+++    GE    +  K D + C V ++AL VL   +  G      + P DC</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>76</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>2.6145e-09</Hsp_evalue>
      <Hsp_query-from>133</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>1315</Hsp_hit-from>
      <Hsp_hit-to>1495</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>182</Hsp_align-len>
      <Hsp_qseq>ESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFR-QIISALDFCHSHSI--WDLKPENLLLDEKNNIRIADFGMA---------------------------------SLQVGDSLLETSCGSPHYACPEVIRGEKYDGR--KADVWSCGVILFALLV</Hsp_qseq>
      <Hsp_hseq>EMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSL-AALLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMIT</Hsp_hseq>
      <Hsp_midline>E  +++++ HP+++  Y V  ++  + + +E+  GG L   L++ GR+  +   + +  Q++  L + H   I   D+KPEN+LLD    I+  DFG A                                 +++  ++ L    G+P Y  PE I G    G+    DVWS G ++  ++ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>77</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>2.72951e-09</Hsp_evalue>
      <Hsp_query-from>157</Hsp_query-from>
      <Hsp_query-to>423</Hsp_query-to>
      <Hsp_hit-from>408</Hsp_hit-from>
      <Hsp_hit-to>498</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>91</Hsp_align-len>
      <Hsp_qseq>EHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSI--WDLKPENLLLDEKNNIRIADFGMAS</Hsp_qseq>
      <Hsp_hseq>DSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLST</Hsp_hseq>
      <Hsp_midline>+ P V+ LY  +++ +YLYL++E + GG+L   L++    T    R +  + I A++  H       D+KP+N+L+D + +I+++DFG+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>78</Hit_num>
  <Hit_id>YDL025C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:405344:407206:-1 gene:YDL025C transcript:YDL025C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RTK1 description:Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002183]</Hit_def>
  <Hit_accession>YDL025C</Hit_accession>
  <Hit_len>620</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>3.06764e-09</Hsp_evalue>
      <Hsp_query-from>130</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>356</Hsp_hit-from>
      <Hsp_hit-to>505</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>154</Hsp_align-len>
      <Hsp_qseq>SESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDY--LVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETS--CGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLV</Hsp_qseq>
      <Hsp_hseq>TEFCIGSTLHHENIVETLDMLTEGDTYLLVMEYAP----YDFFNLVMSNLMTQDEVNCYFKQLCHGVNYLHSMGLAHRDLKLDNCVVTKDGILKLIDFGSAVVFQYPYEDTIVKSHGIVGSDPYLAPELLKQTSYDPRVADVWSIAIIFYCMVL</Hsp_hseq>
      <Hsp_midline>+E  +   + H ++++  D+        LV+E+      +D+  LV    +T  E   +F+Q+   +++ HS  +   DLK +N ++ +   +++ DFG A        D+++++    GS  Y  PE+++   YD R ADVWS  +I + +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>79</Hit_num>
  <Hit_id>YOR267C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:822588:824867:-1 gene:YOR267C transcript:YOR267C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRK1 description:Protein kinase; implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005793]</Hit_def>
  <Hit_accession>YOR267C</Hit_accession>
  <Hit_len>759</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>9.67345e-09</Hsp_evalue>
      <Hsp_query-from>61</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>229</Hsp_hit-from>
      <Hsp_hit-to>416</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>190</Hsp_align-len>
      <Hsp_qseq>VKLGIHSVTGRKVAVKIVNREKLSESV------------LMKLIEHPHVLKLYDVYENKKY--LYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMA-----SLQVGDSLLETSCGSPHYACPEVIRGEK-YDGRKADVWSCGVILFALLV</Hsp_qseq>
      <Hsp_hseq>VKVLVRPTDGATFAVKEFRPRKPNESVKEYAKKCTAEFCIGSTLHHPNVIETVDVFSDSKQNKYYEVMEYCPID--FFAVVMTGKMSRGEINCCLKQLTEGVKYLHSMGLAHRDLKLDNCVMTSQGILKLIDFGSAVVFRYPFEDGVTMAHGIVGSDPYLAPEVITSTKSYDPQCVDIWSIGIIYCCMVL</Hsp_hseq>
      <Hsp_midline>VK+ +    G   AVK     K +ESV            +   + HP+V++  DV+ + K    Y V+E+      F  +V  G+++  E     +Q+   + + HS  +   DLK +N ++  +  +++ DFG A       + G ++     GS  Y  PEVI   K YD +  D+WS G+I   +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>80</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>1.7143e-08</Hsp_evalue>
      <Hsp_query-from>142</Hsp_query-from>
      <Hsp_query-to>549</Hsp_query-to>
      <Hsp_hit-from>89</Hsp_hit-from>
      <Hsp_hit-to>239</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>151</Hsp_align-len>
      <Hsp_qseq>LMKLIEHPHVLKLYDVYE------NKKYLY---LVLEHVS---GGELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSI--WDLKPENLLLDEKNNI-RIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVIL</Hsp_qseq>
      <Hsp_hseq>ILQNIRHPNLVTLEFFFESHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGIAKVCDFGSAQRLDDNTELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCII</Hsp_hseq>
      <Hsp_midline>+++ I HP+++ L   +E      +  +LY    V+E++      E+ +Y     ++  K  + +  QI+ AL   HS SI   DLKP N+L+   + I ++ DFG A     ++ L+T   S  Y  PE++   K    + D+WS G I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>81</Hit_num>
  <Hit_id>YKL198C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:68232:70220:-1 gene:YKL198C transcript:YKL198C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK1 description:Putative serine/threonine protein kinase; regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein; PTK1 has a paralog, PTK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001681]</Hit_def>
  <Hit_accession>YKL198C</Hit_accession>
  <Hit_len>662</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>3.35292e-08</Hsp_evalue>
      <Hsp_query-from>241</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>288</Hsp_hit-from>
      <Hsp_hit-to>417</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>130</Hsp_align-len>
      <Hsp_qseq>ELFDYLVKKGRLTPKEARRF--FRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMASLQVGDSLLETS--------CGSPHYACPEVIR-----------GEKYDGRKADVWSCGVILFALL</Hsp_qseq>
      <Hsp_hseq>DLFAMIQKSGWRSVALAEKFCIFKQVACGVKFCHDQGIAHRDLKPENVLLSPDGVCKLTDFGISDWYHTDPHDLSSPVKKCAGMIGSPPYAPPEVMFYDSKKHYDTELQQPYDPRALDCYGLGIILMTLV</Hsp_hseq>
      <Hsp_midline>+LF  + K G  +   A +F  F+Q+   + FCH   I   DLKPEN+LL      ++ DFG++     D    +S         GSP YA PEV+             + YD R  D +  G+IL  L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>82</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>4.15128e-08</Hsp_evalue>
      <Hsp_query-from>82</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>390</Hsp_hit-from>
      <Hsp_hit-to>565</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>181</Hsp_align-len>
      <Hsp_qseq>VTGRKVAVKIVNR------EKLSESVLMKLIEHP-------HVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGR---LTPKEARRFFRQIISALDFCHSHSI--WDLKPENLLL--DEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLV</Hsp_qseq>
      <Hsp_hseq>LTKEILAVKVVKSRTEYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKNHLCLVFELLSNN-LYE-LLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPELKIIDFGSSCEEA--RTVYTYIQSRFYRAPEIILGIPY-STSIDMWSLGCIVAELFL</Hsp_hseq>
      <Hsp_midline>+T   +AVK+V        + ++E+ +++L+          H L++YD + +K +L LV E +S   L++ L+K+ +   L+ +  R F  QI+ +L       +   DLKPEN+LL   +K  ++I DFG +  +     + T   S  Y  PE+I G  Y     D+WS G I+  L +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>83</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>4.34891e-08</Hsp_evalue>
      <Hsp_query-from>112</Hsp_query-from>
      <Hsp_query-to>588</Hsp_query-to>
      <Hsp_hit-from>200</Hsp_hit-from>
      <Hsp_hit-to>367</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>173</Hsp_align-len>
      <Hsp_qseq>VNREKLSESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGEL----FDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMA--------SLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVLLEKVKRG</Hsp_qseq>
      <Hsp_hseq>ISQSACREMALCRELHNKHLTTLVEIFLERKCVHMVYEYAEHDLLQIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDGCVKIGDLGLARKFHNMLQTLYTGDKVVVTIW----YRAPELLLGARHYTPAVDLWSVGCI-FAELIGLQPIFKG</Hsp_hseq>
      <Hsp_midline>+++    E  L + + + H+  L +++  +K +++V E+     L    F    +K  + P+  R    Q++  + + H + +   DLKP N+++     ++I D G+A        +L  GD ++ T      Y  PE++ G ++     D+WS G I FA L+ L+ + +G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>84</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>6.86837e-08</Hsp_evalue>
      <Hsp_query-from>124</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>77</Hsp_hit-from>
      <Hsp_hit-to>235</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>KLSESVLMKLIEHPHVLKLYDVY------ENKKYLYLVLEHVSGG---ELFDYLVKKGRLTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLD-EKNNIRIADFGMAS-LQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLV</Hsp_qseq>
      <Hsp_hseq>KSRELQILRIADHPNIVKLQYFFTHLSPQDNKVYQHLAMECLPETLQIEINRYVTNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSISYIC-SRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLI</Hsp_hseq>
      <Hsp_midline>K  E  ++++ +HP+++KL   +      +NK Y +L +E +      E+  Y+  K  +  K  R +  QI   + + H   +   D+KP N+L+D E   ++I DFG A  L+     +   C S  Y  PE+I G      + D+W  G ++  +L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>85</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>1.10387e-07</Hsp_evalue>
      <Hsp_query-from>70</Hsp_query-from>
      <Hsp_query-to>549</Hsp_query-to>
      <Hsp_hit-from>30</Hsp_hit-from>
      <Hsp_hit-to>216</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>187</Hsp_align-len>
      <Hsp_qseq>GIHSVTGRKVAVK---------IVNREKLSESVLMKLIEHPHVLKLYD----VYENKKYLYLVLEHVSGGELFDYLVKKGR----LTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMASLQVGDS--------LLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVIL</Hsp_qseq>
      <Hsp_hseq>AIHKPSGIKVAIKKIQPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCIL</Hsp_hseq>
      <Hsp_midline> IH  +G KVA+K          V R      +L    EH +++ + D    V  +K     ++E +   +L   +  +      L+    + F  QI+ AL   HS  +   D+KP NLLL+   ++++ DFG+A      S         +     +  Y  PE++   +      D+WSCG IL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>86</Hit_num>
  <Hit_id>YDL028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:400997:403291:-1 gene:YDL028C transcript:YDL028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MPS1 description:Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]</Hit_def>
  <Hit_accession>YDL028C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>1.36575e-07</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>489</Hsp_hit-from>
      <Hsp_hit-to>648</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>163</Hsp_align-len>
      <Hsp_qseq>VLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKE---ARRFFRQIISALDFCHSHSI--WDLKPENLLLDEKNNIRIADFGMASL---QVGDSLLETSCGSPHYACPEVIRGEKYD--------------GRKADVWSCGVILFALL</Hsp_qseq>
      <Hsp_hseq>LLEKLKDQKRVIQLLDYEMGDGLLYLIME--CGDHDLSQILNQRSGMPLDFNFVRFYTKEMLLCIKVVHDAGIVHSDLKPANFVL-VKGILKIIDFGIANAVPEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMI</Hsp_hseq>
      <Hsp_midline>+L KL +   V++L D       LYL++E   G      ++ +    P +    R + ++++  +   H   I   DLKP N +L  K  ++I DFG+A+       +   ET  G+P+Y  PE +    Y               GR +D+WSCG I++ ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>87</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>2.0952e-07</Hsp_evalue>
      <Hsp_query-from>97</Hsp_query-from>
      <Hsp_query-to>558</Hsp_query-to>
      <Hsp_hit-from>488</Hsp_hit-from>
      <Hsp_hit-to>646</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>166</Hsp_align-len>
      <Hsp_qseq>VAVKIVNREKLSESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGELFDYL-----VKKGRLTPKEARRFFRQIIS---ALDFCHS--HSI-WDLKPENLLLDEKNNIRIADFGMAS-LQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFAL</Hsp_qseq>
      <Hsp_hseq>LEIKILN--EVTNQITMDQEGKEYIIDYISSWKFQNSYYIMTELCENGNLDGFLQEQVIAKKKRL---EDWRIWKIIVELSLALRFIHDSCHIVHLDLKPANVMITFEGNLKLGDFGMATHLPLEDKSFENE-GDREYIAPEIISDCTYD-YKADIFSLGLMIVEI</Hsp_hseq>
      <Hsp_midline>+ +KI+N  +++  + M      +++     ++ +   Y++ E    G L  +L      KK RL   E  R ++ I+    AL F H   H +  DLKP N+++  + N+++ DFGMA+ L + D   E   G   Y  PE+I    YD  KAD++S G+++  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>88</Hit_num>
  <Hit_id>YBR059C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:356861:360187:-1 gene:YBR059C transcript:YBR059C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AKL1 description:Ser-Thr protein kinase; member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization [Source:SGD;Acc:S000000263]</Hit_def>
  <Hit_accession>YBR059C</Hit_accession>
  <Hit_len>1108</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>3.44574e-07</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>567</Hsp_query-to>
      <Hsp_hit-from>97</Hsp_hit-from>
      <Hsp_hit-to>264</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>VLMKLIEHPHVLKLYDVYENKKY-------LYLVLEHVSGGELFDYLVKK--GRLTPKEARRFFRQIISALDFCHSHSI------WDLKPENLLLDEKNNIRIADFGMAS-------LQVGDSLLETSC---GSPHYACPEVIRGEKYD----GRKADVWSCGVILFALLVL</Hsp_qseq>
      <Hsp_hseq>VMKKLKGAPNIVQYFDSNASRRRDGVQGFEVLLLMELCPNKSLLDYMNQRLSTKLTEAEIVKIMYDV--ALSISQMHYLPVSLIHRDIKIENVLVDAKNNFKLADFGSTSTCFPIVTTHQDIALLTQNIYVHTTPQYRSPEMI--DLYRCLPINEKSDIWALGVFLYKLLFF</Hsp_hseq>
      <Hsp_midline>V+ KL   P++++ +D   +++        + L++E      L DY+ ++   +LT  E  +    +  AL     H +       D+K EN+L+D KNN ++ADFG  S            +LL  +     +P Y  PE+I  + Y       K+D+W+ GV L+ LL  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>89</Hit_num>
  <Hit_id>YAR018C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:170396:171703:-1 gene:YAR018C transcript:YAR018C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN3 description:Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol [Source:SGD;Acc:S000000071]</Hit_def>
  <Hit_accession>YAR018C</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>3.88084e-07</Hsp_evalue>
      <Hsp_query-from>127</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>70</Hsp_hit-from>
      <Hsp_hit-to>331</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>83</Hsp_gaps>
      <Hsp_align-len>263</Hsp_align-len>
      <Hsp_qseq>LSESVLMKLIEHPHVLKLY--DVYENKKYLYLVLEHVSGGELFD----YLVKKGRLTPKEARRFFRQIISALDFCHS-------HSIWD----------------LKPENLLL----------------DEKNN-----------------------IRIADFGMA-SLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFAL------------LVLLEKVKRG-VFHMPHFIPPDCQALLRGMIEVDAEKR</Hsp_qseq>
      <Hsp_hseq>IAECSILSQLKHENIVEFYNWDFDEQKEVLYLYMEYCSRGDLSQMIKHYKQEHKYIPEKIVWGILAQLLTALYKCHYGVELPTLTTIYDRMKPPVKGKNIVIHRDLKPGNIFLSYDDSDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLAKSLETSIQFATTYVGTPYYMSPEVLMDQPYSPL-SDIWSLGCVIFEMCSLHPPFQAKNYLELQTKIKNGKCDTVPEYYSRGLNAIIHSMIDVNLRTR</Hsp_hseq>
      <Hsp_midline>++E  ++  ++H ++++ Y  D  E K+ LYL +E+ S G+L      Y  +   +  K       Q+++AL  CH         +I+D                LKP N+ L                +E N+                       +++ DFG+A SL+       T  G+P+Y  PEV+  + Y    +D+WS G ++F +            L L  K+K G    +P +      A++  MI+V+   R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>90</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>3.95903e-07</Hsp_evalue>
      <Hsp_query-from>256</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>118</Hsp_hit-from>
      <Hsp_hit-to>227</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>110</Hsp_align-len>
      <Hsp_qseq>LVKKGR-LTPKEARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNIRIADFGMA-----SLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL</Hsp_qseq>
      <Hsp_hseq>IIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFL</Hsp_hseq>
      <Hsp_midline>++K G+ LT    + F  QI+  L + HS  +   DLKP NLL++    ++I DFG+A     +       L     +  Y  PE++   +   +  DVWS G IL   L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>91</Hit_num>
  <Hit_id>YKL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:347214:349136:-1 gene:YKL048C transcript:YKL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ELM1 description:Serine/threonine protein kinase; regulates the orientation checkpoint, the morphogenesis checkpoint and the metabolic switch from fermentative to oxidative metabolism by phosphorylating the activation loop of Kin4p, Hsl1p and Snf4p respectively; cooperates with Hsl7p in recruiting Hsl1p to the septin ring, a prerequisite for subsequent recruitment, phosphorylation, and degradation of Swe1p; forms part of the bud neck ring; regulates cytokinesis [Source:SGD;Acc:S000001531]</Hit_def>
  <Hit_accession>YKL048C</Hit_accession>
  <Hit_len>640</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>1.15036e-06</Hsp_evalue>
      <Hsp_query-from>289</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>236</Hsp_hit-from>
      <Hsp_hit-to>348</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>53</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>113</Hsp_align-len>
      <Hsp_qseq>ARRFFRQIISALDFCHSHSIW--DLKPENLLLDEKNNI-RIADFGM-----ASLQVGDSLLETS--------CGSPHYACPEVI------RGEKYDGRKADVWSCGVILFALL</Hsp_qseq>
      <Hsp_hseq>AKKILEDMTKGLEYLHSQGCIHRDIKPSNILLDEEEKVAKLSDFGSCIFTPQSLPFSDANFEDCFQRELNKIVGTPAFIAPELCHLGNSKRDFVTDGFKLDIWSLGVTLYCLL</Hsp_hseq>
      <Hsp_midline>A++    +   L++ HS      D+KP N+LLDE+  + +++DFG       SL   D+  E           G+P +  PE+       R    DG K D+WS GV L+ LL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>92</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.595</Hsp_bit-score>
      <Hsp_score>109</Hsp_score>
      <Hsp_evalue>7.75463e-06</Hsp_evalue>
      <Hsp_query-from>118</Hsp_query-from>
      <Hsp_query-to>558</Hsp_query-to>
      <Hsp_hit-from>401</Hsp_hit-from>
      <Hsp_hit-to>557</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>158</Hsp_align-len>
      <Hsp_qseq>REKLSESVLMKLIEHPHVLKLYDVYENKKYLYLVLEHVSGGEL---FDYLVKKGRLTPKEARRFFRQIISAL-DFCHSHSI--WDLKPENLLLD-EKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGR----KADVWSCGVILFAL</Hsp_qseq>
      <Hsp_hseq>RQILMELEVLHKCNSPYIVDFYGAFFIEGAVYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSANQGTVKLCDFGVSGNLVA-SLAKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEM</Hsp_hseq>
      <Hsp_midline>R+ L E  ++     P+++  Y  +  +  +Y+ +E++ GG L   +D   + G +   +       +I  L +    H+I   D+KP N+L    +  +++ DFG++   V  SL +T+ G   Y  PE I+    D      ++D+WS G+ +  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>933522469</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061698-RA transcript Note:&quot;Similar to lmf2 Lipase maturation factor 2 (Xenopus laevis)&quot; offset:28 AED:0.42 eAED:0.42 QI:28|0.37|0.33|0.88|0.87|0.77|9|0|596</Iteration_query-def>
  <Iteration_query-len>1819</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1168691237</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0013861-RA transcript Note:&quot;Protein of unknown function&quot; offset:346 AED:0.29 eAED:0.33 QI:346|0.25|0.33|0.88|0.37|0.44|9|0|278</Iteration_query-def>
  <Iteration_query-len>1183</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>92</Statistics_hsp-len>
      <Statistics_eff-space>696673834</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0045669-RA transcript Note:&quot;Protein of unknown function&quot; offset:50 AED:1.00 eAED:1.00 QI:50|0|0|0|0.33|0.3|10|0|573</Iteration_query-def>
  <Iteration_query-len>1772</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1132098165</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061700-RA transcript Note:&quot;Similar to TNNT2 Troponin T, cardiac muscle isoforms (Gallus gallus)&quot; offset:4 AED:0.16 eAED:0.16 QI:4|0.8|0.83|1|0.6|0.5|6|0|215</Iteration_query-def>
  <Iteration_query-len>652</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>86</Statistics_hsp-len>
      <Statistics_eff-space>307387177</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0045672-RA transcript Note:&quot;Similar to GUCA1A Guanylyl cyclase-activating protein 1 (Lithobates pipiens)&quot; offset:22 AED:0.20 eAED:0.20 QI:22|0|0|0.66|0|0.66|3|0|173</Iteration_query-def>
  <Iteration_query-len>544</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDR373W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1222759:1223331:1 gene:YDR373W transcript:YDR373W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRQ1 description:N-myristoylated calcium-binding protein; may have a role in intracellular signaling through its regulation of the phosphatidylinositol 4-kinase Pik1p; member of the recoverin/frequenin branch of the EF-hand superfamily; human NCS1 functionally complements the heat sensitivity of a frq1 ts mutant [Source:SGD;Acc:S000002781]</Hit_def>
  <Hit_accession>YDR373W</Hit_accession>
  <Hit_len>190</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.8929</Hsp_bit-score>
      <Hsp_score>224</Hsp_score>
      <Hsp_evalue>7.49956e-24</Hsp_evalue>
      <Hsp_query-from>68</Hsp_query-from>
      <Hsp_query-to>478</Hsp_query-to>
      <Hsp_hit-from>26</Hsp_hit-from>
      <Hsp_hit-to>167</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>146</Hsp_align-len>
      <Hsp_qseq>EIHLWYKKFMRECPSGQLTLHEF----KQFFGISSVTAEGNAYIEQMFRTFDMNKDGYIDFMEYVAALSLVLRGKVEQKLRWYFKMYDSDGNGCIDKGELLNIIKAIRGIDGCA-----HETTPEEFTSIVFDRIDVDRDGERTDD</Hsp_qseq>
      <Hsp_hseq>EIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFAN----HLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLD</Hsp_hseq>
      <Hsp_midline>EI  W+K F+R+CPSGQL   +F    KQFF   S     N     +F  FD + +G+I F E++  LS   RG +E+KL W F++YD + +G I   E+L I+ ++  + G        E TPE     +F  +D + DG  T D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YKL190W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:82947:83550:1 gene:YKL190W transcript:YKL190W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CNB1 description:Calcineurin B; regulatory subunit of calcineurin, a Ca++/calmodulin-regulated type 2B protein phosphatase which regulates Crz1p (stress-response transcription factor); other calcineurin subunit encoded by CNA1 and/or CMP1; regulates function of Aly1p alpha-arrestin; myristoylation by Nmt1p reduces calcineurin activity in response to submaximal Ca signals, is needed to prevent constitutive phosphatase activity; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001673]</Hit_def>
  <Hit_accession>YKL190W</Hit_accession>
  <Hit_len>175</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>2.03501e-13</Hsp_evalue>
      <Hsp_query-from>68</Hsp_query-from>
      <Hsp_query-to>382</Hsp_query-to>
      <Hsp_hit-from>22</Hsp_hit-from>
      <Hsp_hit-to>124</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>108</Hsp_align-len>
      <Hsp_qseq>EIHLWYKKFMR--ECPSGQLTLHEFKQFFGISSVTAEGNAYIEQMFRTFDMNKDGYIDFMEYVAALSLVL-RGKVEQKLRWYFKMYDSDGNGCIDKGELLNIIKAIRG</Hsp_qseq>
      <Hsp_hseq>EIERLRKRFMKLDRDSSGSIDKNEFMSIPGVSS-----NPLAGRIMEVFDADNSGDVDFQEFITGLSIFSGRGSKDEKLRFAFKIYDIDKDGFISNGELFIVLKIMVG</Hsp_hseq>
      <Hsp_midline>EI    K+FM+     SG +  +EF    G+SS     N    ++   FD +  G +DF E++  LS+   RG  ++KLR+ FK+YD D +G I  GEL  ++K + G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>84</Statistics_hsp-len>
      <Statistics_eff-space>228887699</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061708-RA transcript Note:&quot;Similar to Kcna3 Potassium voltage-gated channel subfamily A member 3 (Mus musculus)&quot; offset:0 AED:0.05 eAED:0.05 QI:0|0|0|0.5|1|1|2|0|559</Iteration_query-def>
  <Iteration_query-len>1680</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1063486155</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061709-RA transcript Note:&quot;Similar to Kcna3 Potassium voltage-gated channel subfamily A member 3 (Mus musculus)&quot; offset:0 AED:0.05 eAED:0.05 QI:0|-1|0|1|-1|1|1|0|545</Iteration_query-def>
  <Iteration_query-len>1638</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>1036737484</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0013862-RA transcript Note:&quot;Similar to spc24 Kinetochore protein Spc24 (Xenopus laevis)&quot; offset:240 AED:1.00 eAED:1.00 QI:240|0|0|0|0|0|6|386|199</Iteration_query-def>
  <Iteration_query-len>1226</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>92</Statistics_hsp-len>
      <Statistics_eff-space>728969972</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061699-RA transcript Note:&quot;Protein of unknown function&quot; offset:108 AED:0.00 eAED:0.00 QI:108|1|1|1|1|1|3|3889|257</Iteration_query-def>
  <Iteration_query-len>4771</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3322355029</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

