<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0058392-RA transcript Note:&quot;Similar to OTOL1 Otolin-1 (Homo sapiens)&quot; offset:0 AED:0.32 eAED:0.32 QI:0|0|0|0.28|1|1|7|0|221</BlastOutput_query-def>
  <BlastOutput_query-len>666</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058392-RA transcript Note:&quot;Similar to OTOL1 Otolin-1 (Homo sapiens)&quot; offset:0 AED:0.32 eAED:0.32 QI:0|0|0|0.28|1|1|7|0|221</Iteration_query-def>
  <Iteration_query-len>666</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>86</Statistics_hsp-len>
      <Statistics_eff-space>319119512</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058387-RA transcript Note:&quot;Similar to IVL Involucrin (Pongo pygmaeus)&quot; offset:0 AED:0.55 eAED:0.56 QI:0|0|0|0.33|1|1|3|0|225</Iteration_query-def>
  <Iteration_query-len>678</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>86</Statistics_hsp-len>
      <Statistics_eff-space>328505380</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058390-RA transcript Note:&quot;Similar to PRKCSH Glucosidase 2 subunit beta (Homo sapiens)&quot; offset:0 AED:0.21 eAED:0.21 QI:0|0.07|0.14|0.14|0.92|0.85|14|1760|380</Iteration_query-def>
  <Iteration_query-len>2903</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDR221W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:907330:909438:1 gene:YDR221W transcript:YDR221W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GTB1 description:Glucosidase II beta subunit, forms a complex with alpha subunit Rot2p; involved in removal of two glucose residues from N-linked glycans during glycoprotein biogenesis in the ER; relocalizes from ER to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000002629]</Hit_def>
  <Hit_accession>YDR221W</Hit_accession>
  <Hit_len>702</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>2.87049e-06</Hsp_evalue>
      <Hsp_query-from>31</Hsp_query-from>
      <Hsp_query-to>144</Hsp_query-to>
      <Hsp_hit-from>99</Hsp_hit-from>
      <Hsp_hit-to>136</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>25</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>38</Hsp_align-len>
      <Hsp_qseq>NGNFHCTNAGYRPQNIPSSRVNDGICDCCDTTDEYNSG</Hsp_qseq>
      <Hsp_hseq>NKYFYCDNKGFIPRYIRKSEVADGICDCCDCSDELLSG</Hsp_hseq>
      <Hsp_midline>N  F+C N G+ P+ I  S V DGICDCCD +DE  SG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>1962258956</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0046423-RA transcript Note:&quot;Similar to DMRTA2 Doublesex- and mab-3-related transcription factor A2 (Homo sapiens)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0|0|5|2|380</Iteration_query-def>
  <Iteration_query-len>1142</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>668591963</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058376-RA transcript Note:&quot;Similar to tal1 T-cell acute lymphocytic leukemia protein 1 homolog (Danio rerio)&quot; offset:0 AED:0.16 eAED:1.00 QI:0|0|0|0.5|0.8|0.66|6|0|1326</Iteration_query-def>
  <Iteration_query-len>3981</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2755394542</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0030957-RA transcript Note:&quot;Similar to foxd1 Forkhead box protein D1 (Xenopus tropicalis)&quot; offset:0 AED:0.18 eAED:0.18 QI:0|0|0|0.5|0|0|2|2|176</Iteration_query-def>
  <Iteration_query-len>530</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YCR065W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:229310:231004:1 gene:YCR065W transcript:YCR065W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HCM1 description:Forkhead transcription factor; drives S-phase activation of genes involved in chromosome segregation, spindle dynamics, budding; also activates genes involved in respiration, use of alternative energy sources (like proline), NAD synthesis, oxidative stress resistance; key factor in early adaptation to nutrient deficiency and diauxic shift; suppressor of calmodulin mutants with specific SPB assembly defects; ortholog of C. elegans lifespan regulator PHA-4 [Source:SGD;Acc:S000000661]</Hit_def>
  <Hit_accession>YCR065W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.1301</Hsp_bit-score>
      <Hsp_score>235</Hsp_score>
      <Hsp_evalue>9.79807e-24</Hsp_evalue>
      <Hsp_query-from>142</Hsp_query-from>
      <Hsp_query-to>405</Hsp_query-to>
      <Hsp_hit-from>109</Hsp_hit-from>
      <Hsp_hit-to>194</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>88</Hsp_align-len>
      <Hsp_qseq>KPPYSYIALITMAILQSPKKRLTLSEICDFISNRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNG</Hsp_qseq>
      <Hsp_hseq>KPPYSYATLICLAILQSQEGKLTLSQIYHWIHVHFPYYKQKDASWQNSIRHNLSLNDAFIKT--EKSCDGKGHFWEVRPGAETKFFKG</Hsp_hseq>
      <Hsp_midline>KPPYSY  LI +AILQS + +LTLS+I  +I   FPYY++K  +WQNSIRHNLSLND F+K   E    GKG++W + P +   F  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YNL068C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:495701:498289:-1 gene:YNL068C transcript:YNL068C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FKH2 description:Forkhead family transcription factor; rate-limiting activator of replication origins; evolutionarily conserved regulator of lifespan; binds multiple chromosomal elements with distinct specificities, cell cycle dynamics; positively regulates transcriptional elongation; facilitates clustering, activation of early-firing replication origins; negative role in chromatin silencing at HML and HMR; major role in expression of G2/M phase genes; relocalizes to cytosol under hypoxia [Source:SGD;Acc:S000005012]</Hit_def>
  <Hit_accession>YNL068C</Hit_accession>
  <Hit_len>862</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.1301</Hsp_bit-score>
      <Hsp_score>235</Hsp_score>
      <Hsp_evalue>1.00474e-23</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>372</Hsp_query-to>
      <Hsp_hit-from>339</Hsp_hit-from>
      <Hsp_hit-to>416</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>78</Hsp_align-len>
      <Hsp_qseq>VKPPYSYIALITMAILQSPKKRLTLSEICDFISNRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTL</Hsp_qseq>
      <Hsp_hseq>VKPPHSYATMITQAILSSPEGVISLADIYKYISSNYAYYRFAKSGWQNSIRHNLSLNKAFEKVPRRPNEPGKGMKWRI</Hsp_hseq>
      <Hsp_midline>VKPP+SY  +IT AIL SP+  ++L++I  +IS+ + YYR     WQNSIRHNLSLN  F K+PR P  PGKG  W +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YIL131C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:100781:102235:-1 gene:YIL131C transcript:YIL131C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FKH1 description:Forkhead family transcription factor; rate-limiting replication origin activator; evolutionarily conserved lifespan regulator; binds multiple chromosomal elements with distinct specificities, cell cycle dynamics; regulates transcription elongation, chromatin silencing at mating loci, expression of G2/M phase genes; facilitates clustering, activation of early-firing replication origins; binds HML recombination enhancer, regulates donor preference during mating-type switching [Source:SGD;Acc:S000001393]</Hit_def>
  <Hit_accession>YIL131C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.1225</Hsp_bit-score>
      <Hsp_score>222</Hsp_score>
      <Hsp_evalue>4.72453e-22</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>402</Hsp_query-to>
      <Hsp_hit-from>302</Hsp_hit-from>
      <Hsp_hit-to>389</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>88</Hsp_align-len>
      <Hsp_qseq>VKPPYSYIALITMAILQSPKKRLTLSEICDFISNRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDN</Hsp_qseq>
      <Hsp_hseq>IKPPQSYASMITQAILSTPEGSISLADIYKFISDNYAFYRFSQMAWQNSVRHNLSLNKAFEKVPKRAGQQGKGMNWKISDEVRRDFLN</Hsp_hseq>
      <Hsp_midline>+KPP SY ++IT AIL +P+  ++L++I  FIS+ + +YR    AWQNS+RHNLSLN  F K+P+  G  GKG  W +  E    F N</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YPR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:733623:736433:-1 gene:YPR104C transcript:YPR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FHL1 description:Regulator of ribosomal protein (RP) transcription; has forkhead associated domain that binds phosphorylated proteins; recruits coactivator Ifh1p or corepressor Crf1p to RP gene promoters; also has forkhead DNA-binding domain though in vitro DNA binding assays give inconsistent results; computational analyses suggest it binds DNA directly at highly active RP genes and indirectly through Rap1p motifs at others; suppresses RNA pol III and splicing factor prp4 mutants [Source:SGD;Acc:S000006308]</Hit_def>
  <Hit_accession>YPR104C</Hit_accession>
  <Hit_len>936</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>2.51496e-13</Hsp_evalue>
      <Hsp_query-from>142</Hsp_query-from>
      <Hsp_query-to>381</Hsp_query-to>
      <Hsp_hit-from>461</Hsp_hit-from>
      <Hsp_hit-to>537</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>81</Hsp_align-len>
      <Hsp_qseq>KPPYSYIALITMAILQ-SPKKRLTLSEICDFISNRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPE</Hsp_qseq>
      <Hsp_hseq>KPTVSYSAMLTTCIRKYSTAKGMSLSEIYAGIRELFPYYKYCPDGWQSSVRHNLSLNKSFRKVSKE----GKGWLWGLDEE</Hsp_hseq>
      <Hsp_midline>KP  SY A++T  I + S  K ++LSEI   I   FPYY+     WQ+S+RHNLSLN  F K+ +E    GKG  W LD E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>83</Statistics_hsp-len>
      <Statistics_eff-space>220062831</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0043912-RA transcript Note:&quot;Similar to MRPL55 39S ribosomal protein L55, mitochondrial (Homo sapiens)&quot; offset:64 AED:0.39 eAED:0.39 QI:64|0.5|0|1|0|0|3|0|120</Iteration_query-def>
  <Iteration_query-len>427</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>81</Statistics_hsp-len>
      <Statistics_eff-space>145147487</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058382-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.08 eAED:0.16 QI:0|0|0.5|1|0|0|2|847|38</Iteration_query-def>
  <Iteration_query-len>964</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>535935477</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058377-RA transcript Note:&quot;Similar to FREM1 FRAS1-related extracellular matrix protein 1 (Homo sapiens)&quot; offset:0 AED:0.14 eAED:0.15 QI:0|0|0|0.85|1|1|28|0|1616</Iteration_query-def>
  <Iteration_query-len>4851</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3382680238</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058378-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.29 eAED:0.31 QI:0|0.12|0.22|0.44|1|1|9|1253|440</Iteration_query-def>
  <Iteration_query-len>2576</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1723122920</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058379-RA transcript Note:&quot;Similar to EPS15 Epidermal growth factor receptor substrate 15 (Homo sapiens)&quot; offset:0 AED:0.51 eAED:0.51 QI:0|0.42|0.37|0.75|0.57|0.62|8|0|272</Iteration_query-def>
  <Iteration_query-len>819</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YBL047C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:127895:132040:-1 gene:YBL047C transcript:YBL047C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:EDE1 description:Scaffold protein involved in the formation of early endocytic sites; putative regulator of cytokinesis; homo-oligomerization is required for localization to and organization of endocytic sites; has a network of interactions with other endocytic proteins; binds membranes in a ubiquitin-dependent manner; may also bind ubiquitinated membrane-associated proteins; interacts with Cmk2 and functions upstream of CMK2 in regulating non-apoptotic cell death; homolog of mammalian Eps15 [Source:SGD;Acc:S000000143]</Hit_def>
  <Hit_accession>YBL047C</Hit_accession>
  <Hit_len>1381</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.5666</Hsp_bit-score>
      <Hsp_score>192</Hsp_score>
      <Hsp_evalue>7.49857e-17</Hsp_evalue>
      <Hsp_query-from>37</Hsp_query-from>
      <Hsp_query-to>666</Hsp_query-to>
      <Hsp_hit-from>12</Hsp_hit-from>
      <Hsp_hit-to>200</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>210</Hsp_align-len>
      <Hsp_qseq>SSGNPVYEKYYRLVDPGNTGQVGAAQAVVFLKKSGLPDLTLGKIWEVADPEGKGYLEKQGFYVALRLVACAQNALNVSLSSLDFPVPVPKFPEEKAKFDSIYDSLKPQNGLLSGEKVWDLSDIDRDGFLDRDEFSVSQAVSAAERLKYDEMFTKLDKDGDGQVTGLEVKEVFMKTGLSPAVLAQIWALSDTRQCGKLTRDQFGMAMHLVQ</Hsp_qseq>
      <Hsp_hseq>SQEQAFYNQKFHQLDTEDLGVVTGEAVRPLFASSGLPGQLLSQVWATVDIDNKGFLNLNEFSAALRMIAQLQNAPNQPISAALY----ESTPTQLASFSINQNPAPMQSGSATGNT--NNTDI--------------PALSSNDIAKFSQLFDRTAK-GAQTVAGDKAKDIFLKARLPNQTLGEIWALCDRDASGVLDKSEFIMAMYLIQ</Hsp_hseq>
      <Hsp_midline>S     Y + +  +D  + G V           SGLP   L ++W   D + KG+L    F  ALR++A  QNA N  +S+  +       P + A F    +    Q+G  +G    + +DI               A+S+ +  K+ ++F +  K G   V G + K++F+K  L    L +IWAL D    G L + +F MAM+L+Q</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>6.05578e-12</Hsp_evalue>
      <Hsp_query-from>61</Hsp_query-from>
      <Hsp_query-to>672</Hsp_query-to>
      <Hsp_hit-from>138</Hsp_hit-from>
      <Hsp_hit-to>345</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>212</Hsp_align-len>
      <Hsp_qseq>KYYRLVDPGNTG--QVGAAQAVVFLKKSGLPDLTLGKIWEVADPEGKGYLEKQGFYVALRLVACAQNALNVSLSSLDFPVPVPKFPEEKAKFDSIYDSLKPQNGLLSGEKVWDLSDIDRDGFLDR---DEFSVSQA---VSAAERLKYDEMFTKLDKDGDGQVTGLEVKEVFMKTGLSPAVLAQIWALSDTRQCGKLTRDQFGMAMHLVQEK</Hsp_qseq>
      <Hsp_hseq>KFSQLFDRTAKGAQTVAGDKAKDIFLKARLPNQTLGEIWALCDRDASGVLDKSEFIMAMYLI---QLCMSHHPSMNTPPAVLPTQLWDSIRLEPVVVNQPNRTTPLSANST-GVSSLTRHSTISRLSTGAFSNAASDWSLSFEKKQQFDAIFDSLDKQHAGSLSSAVLVPFFLSSRLNQETLATIWDLADIHNNAEFTKLEFAIAMFLIQKK</Hsp_hseq>
      <Hsp_midline>K+ +L D    G   V   +A     K+ LP+ TLG+IW + D +  G L+K  F +A+ L+   Q  ++   S    P  +P    +  + + +  +   +   LS      +S + R   + R     FS + +   +S  ++ ++D +F  LDK   G ++   +   F+ + L+   LA IW L+D     + T+ +F +AM L+Q+K</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>8.0374e-07</Hsp_evalue>
      <Hsp_query-from>454</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>10</Hsp_hit-from>
      <Hsp_hit-to>81</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>42</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>72</Hsp_align-len>
      <Hsp_qseq>VSAAERLKYDEMFTKLDKDGDGQVTGLEVKEVFMKTGLSPAVLAQIWALSDTRQCGKLTRDQFGMAMHLVQE</Hsp_qseq>
      <Hsp_hseq>LSSQEQAFYNQKFHQLDTEDLGVVTGEAVRPLFASSGLPGQLLSQVWATVDIDNKGFLNLNEFSAALRMIAQ</Hsp_hseq>
      <Hsp_midline>+S+ E+  Y++ F +LD +  G VTG  V+ +F  +GL   +L+Q+WA  D    G L  ++F  A+ ++ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YIR006C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:365466:369908:-1 gene:YIR006C transcript:YIR006C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PAN1 description:Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p; associates with actin patches on cell cortex; promotes protein-protein interactions essential for endocytosis; binds to and activates Arp2/3 complex in vitro; phosphorylation of Thr-1225 is regulated by MAPK Hog1p in response to osmotic stress; previously thought to be a subunit of poly(A) ribonuclease [Source:SGD;Acc:S000001445]</Hit_def>
  <Hit_accession>YIR006C</Hit_accession>
  <Hit_len>1480</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>2.40263e-11</Hsp_evalue>
      <Hsp_query-from>454</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>266</Hsp_hit-from>
      <Hsp_hit-to>337</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>72</Hsp_align-len>
      <Hsp_qseq>VSAAERLKYDEMFTKLDKDGDGQVTGLEVKEVFMKTGLSPAVLAQIWALSDTRQCGKLTRDQFGMAMHLVQE</Hsp_qseq>
      <Hsp_hseq>ITAQDQAKFETLFRSIVTNGSNTVSGANCRKILMRSGLPPSQLARIWTLCDTSKAGELLFPEFALAMHLIND</Hsp_hseq>
      <Hsp_midline>++A ++ K++ +F  +  +G   V+G   +++ M++GL P+ LA+IW L DT + G+L   +F +AMHL+ +</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>3.86863e-08</Hsp_evalue>
      <Hsp_query-from>439</Hsp_query-from>
      <Hsp_query-to>675</Hsp_query-to>
      <Hsp_hit-from>591</Hsp_hit-from>
      <Hsp_hit-to>669</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>26</Hsp_identity>
      <Hsp_positive>40</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>79</Hsp_align-len>
      <Hsp_qseq>SVSQAVSAAERLKYDEMFTKLDKDGDGQVTGLEVKEVFMKTGLSPAVLAQIWALSDTRQCGKLTRDQFGMAMHLVQEKI</Hsp_qseq>
      <Hsp_hseq>SSQDKISTEEKSLFYKIFETFDTQNKGLLDSPTAVEIFRKSGLNRADLEQIWNLCDINNTGQLNKQEFALGMHLVYGKL</Hsp_hseq>
      <Hsp_midline>S    +S  E+  + ++F   D    G +      E+F K+GL+ A L QIW L D    G+L + +F + MHLV  K+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>88</Statistics_hsp-len>
      <Statistics_eff-space>431654395</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058380-RA transcript Note:&quot;Similar to STIL SCL-interrupting locus protein (Homo sapiens)&quot; offset:0 AED:0.17 eAED:0.17 QI:0|1|0.5|1|1|1|2|1717|392</Iteration_query-def>
  <Iteration_query-len>2896</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>1957737622</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058381-RA transcript Note:&quot;Similar to stil SCL-interrupting locus protein homolog (Danio rerio)&quot; offset:0 AED:0.79 eAED:0.79 QI:0|0|0|0.22|1|0.88|9|0|438</Iteration_query-def>
  <Iteration_query-len>1317</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>93</Statistics_hsp-len>
      <Statistics_eff-space>795892382</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0043910-RA transcript Note:&quot;Similar to trabd2b Metalloprotease TIKI2 (Xenopus tropicalis)&quot; offset:1 AED:0.22 eAED:0.22 QI:1|0|0|0.33|0.2|0.33|6|1|338</Iteration_query-def>
  <Iteration_query-len>1016</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>575376616</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0043911-RA transcript Note:&quot;Similar to SLC1A1 Excitatory amino acid transporter 3 (Oryctolagus cuniculus)&quot; offset:357 AED:0.40 eAED:0.49 QI:357|0|0|0.81|0.2|0.27|11|0|487</Iteration_query-def>
  <Iteration_query-len>1821</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1170978304</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058383-RA transcript Note:&quot;Similar to SPATA6 Spermatogenesis-associated protein 6 (Homo sapiens)&quot; offset:399 AED:0.29 eAED:0.29 QI:399|0.62|0.88|1|0.87|0.77|9|1376|232</Iteration_query-def>
  <Iteration_query-len>2474</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1646035842</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058384-RA transcript Note:&quot;Similar to AGBL4 Cytosolic carboxypeptidase 6 (Homo sapiens)&quot; offset:397 AED:0.39 eAED:0.39 QI:397|0.33|0.5|1|0.33|0.25|4|0|184</Iteration_query-def>
  <Iteration_query-len>952</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>526655209</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0043916-RA transcript Note:&quot;Protein of unknown function&quot; offset:796 AED:0.22 eAED:0.22 QI:796|1|0.66|1|0.2|0.5|6|1487|144</Iteration_query-def>
  <Iteration_query-len>2718</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>1824358269</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0043917-RA transcript Note:&quot;Similar to RNF11 RING finger protein 11 (Homo sapiens)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0|0.5|2|15|81</Iteration_query-def>
  <Iteration_query-len>261</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>58</Statistics_hsp-len>
      <Statistics_eff-space>73406743</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0027426-RA transcript Note:&quot;Similar to Mast4 Microtubule-associated serine/threonine-protein kinase 4 (Mus musculus)&quot; offset:2854 AED:1.00 eAED:1.00 QI:2854|0|0|0|0.59|0.56|23|0|608</Iteration_query-def>
  <Iteration_query-len>4681</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YFL033C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:69115:74427:-1 gene:YFL033C transcript:YFL033C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM15 description:Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase [Source:SGD;Acc:S000001861]</Hit_def>
  <Hit_accession>YFL033C</Hit_accession>
  <Hit_len>1770</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>158.303</Hsp_bit-score>
      <Hsp_score>399</Hsp_score>
      <Hsp_evalue>3.80385e-39</Hsp_evalue>
      <Hsp_query-from>627</Hsp_query-from>
      <Hsp_query-to>1094</Hsp_query-to>
      <Hsp_hit-from>789</Hsp_hit-from>
      <Hsp_hit-to>945</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>157</Hsp_align-len>
      <Hsp_qseq>PCEEDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTF-AENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKIGLM</Hsp_qseq>
      <Hsp_hseq>PSIKDYDILKPISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDKPYVARLFASFQNKDNLFLVMEYLPGGDLATLIKMMGYLPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLIDNAGHVKLTDFGLSRAGLI</Hsp_hseq>
      <Hsp_midline>P  +D++ +K IS GAYG+VYL R K T   FA+K + K ++I +NQ+     ER I+   ++ P+V  +F SF+ K +L +VMEY+ GGD ATL+K +G LP   A+ Y  E V+ +  +H  GI+H DLKP+NLLI + GHVKLTDFGLS+ GL+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>2.90168e-11</Hsp_evalue>
      <Hsp_query-from>1165</Hsp_query-from>
      <Hsp_query-to>1389</Hsp_query-to>
      <Hsp_hit-from>1205</Hsp_hit-from>
      <Hsp_hit-to>1285</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>81</Hsp_align-len>
      <Hsp_qseq>IVWPEGEDA------LPSDVQDLITGLLERNPLERLGTGGAFEVKQHQFFHSLDWDGLLRQKAEFVPQLESEEDTSYFDTR</Hsp_qseq>
      <Hsp_hseq>IQWPEFKNEEEEREFLTPEAKDLIEKLLVVDPAKRLGAKGIQEIKDHPYFKNVDWDHVYDEEASFVPTIDNPEDTDYFDLR</Hsp_hseq>
      <Hsp_midline>I WPE ++       L  + +DLI  LL  +P +RLG  G  E+K H +F ++DWD +  ++A FVP +++ EDT YFD R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>137.502</Hsp_bit-score>
      <Hsp_score>345</Hsp_score>
      <Hsp_evalue>3.62215e-35</Hsp_evalue>
      <Hsp_query-from>618</Hsp_query-from>
      <Hsp_query-to>1082</Hsp_query-to>
      <Hsp_hit-from>62</Hsp_hit-from>
      <Hsp_hit-to>216</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>155</Hsp_align-len>
      <Hsp_qseq>KKKPCEEDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSK</Hsp_qseq>
      <Hsp_hseq>KGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAK</Hsp_hseq>
      <Hsp_midline>K K    DF+ ++ +  G++G V+LVR     + +A+K + KQ ++   Q++    ER +L   E+PF++ M+ +F+  R++ MVM+Y+EGG+  +LL+     P  +A+ Y AE +LALEYLH + I++RDLKP+N+L+   GH+K+TDFG +K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>141.739</Hsp_bit-score>
      <Hsp_score>356</Hsp_score>
      <Hsp_evalue>1.11005e-34</Hsp_evalue>
      <Hsp_query-from>636</Hsp_query-from>
      <Hsp_query-to>1079</Hsp_query-to>
      <Hsp_hit-from>350</Hsp_hit-from>
      <Hsp_hit-to>497</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>148</Hsp_align-len>
      <Hsp_qseq>EDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLS</Hsp_qseq>
      <Hsp_hseq>EDFHTVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLS</Hsp_hseq>
      <Hsp_midline>EDF T+K+I  GA+G V LV+ K+T + +AMK + K  +  ++Q+     ERD+L  +++P+VV ++ SF+  ++L ++ME++ GGD  T+L        D+ + Y AE +LA+E +H  G +HRD+KPDN+LI   GH+KL+DFGLS</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>137.887</Hsp_bit-score>
      <Hsp_score>346</Hsp_score>
      <Hsp_evalue>5.27381e-34</Hsp_evalue>
      <Hsp_query-from>471</Hsp_query-from>
      <Hsp_query-to>1079</Hsp_query-to>
      <Hsp_hit-from>117</Hsp_hit-from>
      <Hsp_hit-to>322</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>206</Hsp_align-len>
      <Hsp_qseq>DIPRYIISQLGLTRDPLEEMAQLSSC-DSGNPETPETDDATDSRAAESLPKK--KPCEEDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLS</Hsp_qseq>
      <Hsp_hseq>DMFDYVISRRQRTKQVLEYLQQQSQLPNSDQIKLNEEWSSYLQREHQVLRKRRLKPKNRDFEMITQVGQGGYGQVYLARKKDTKEVCALKILNKKLLFKLNETKHVLTERDILTTTRSEWLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINTRCLKSGHARFYISEMFCAVNALHDLGYTHRDLKPENFLIDAKGHIKLTDFGLA</Hsp_hseq>
      <Hsp_midline>D+  Y+IS+   T+  LE + Q S   +S   +  E   +   R  + L K+  KP   DFE I  +  G YG VYL R K+T++  A+K +NK+ L   N+ +    ERDILT   + ++V +  +F+  + L + ME+V GGD  TLL N   L    A+ Y +E   A+  LH+ G  HRDLKP+N LI + GH+KLTDFGL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>130.954</Hsp_bit-score>
      <Hsp_score>328</Hsp_score>
      <Hsp_evalue>6.52751e-33</Hsp_evalue>
      <Hsp_query-from>636</Hsp_query-from>
      <Hsp_query-to>1082</Hsp_query-to>
      <Hsp_hit-from>85</Hsp_hit-from>
      <Hsp_hit-to>233</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>149</Hsp_align-len>
      <Hsp_qseq>EDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSK</Hsp_qseq>
      <Hsp_hseq>QDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAK</Hsp_hseq>
      <Hsp_midline>+DF+ ++ +  G++G V+L+R +   + +AMK + K+ ++   Q++    ER +L+   +PF++ M+ +F+  + + M+M+Y+EGG+  +LL+     P  +A+ Y AE  LALEYLH+  I++RDLKP+N+L+   GH+K+TDFG +K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>130.568</Hsp_bit-score>
      <Hsp_score>327</Hsp_score>
      <Hsp_evalue>1.06163e-32</Hsp_evalue>
      <Hsp_query-from>639</Hsp_query-from>
      <Hsp_query-to>1082</Hsp_query-to>
      <Hsp_hit-from>87</Hsp_hit-from>
      <Hsp_hit-to>234</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>148</Hsp_align-len>
      <Hsp_qseq>DFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSK</Hsp_qseq>
      <Hsp_hseq>DFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAK</Hsp_hseq>
      <Hsp_midline>DF+ ++ +  G++G V+L+R     + +A+K + K  ++   Q++    ER +L+   +PF++ M+ +F+  + + MVM+Y+EGG+  +LL+     P  +A+ Y AE  LALEYLH+  I++RDLKP+N+L+   GH+K+TDFG +K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>131.339</Hsp_bit-score>
      <Hsp_score>329</Hsp_score>
      <Hsp_evalue>2.54355e-31</Hsp_evalue>
      <Hsp_query-from>636</Hsp_query-from>
      <Hsp_query-to>1118</Hsp_query-to>
      <Hsp_hit-from>410</Hsp_hit-from>
      <Hsp_hit-to>573</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>164</Hsp_align-len>
      <Hsp_qseq>EDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFA---ENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKIGLMSLTTNLAA</Hsp_qseq>
      <Hsp_hseq>QDFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCG</Hsp_hseq>
      <Hsp_midline>+DFE ++L+  G +G VY V+ K+T++ +AMK ++K+ ++ +N+I     ER+IL       +PF+VG+  SF+T   L +V +Y+ GG+    L+  G    D A+ Y AE VLALE+LH+  IV+RDLKP+N+L+ + G++ L DFGLSK  L   T     </Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>2.11325e-06</Hsp_evalue>
      <Hsp_query-from>1186</Hsp_query-from>
      <Hsp_query-to>1383</Hsp_query-to>
      <Hsp_hit-from>634</Hsp_hit-from>
      <Hsp_hit-to>702</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>38</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>69</Hsp_align-len>
      <Hsp_qseq>DALPSDVQDLITGLLERNPLERLGT-GGAFEVKQHQFFHSLDWDGLLRQKA--EFVPQLESEEDTSYFD</Hsp_qseq>
      <Hsp_hseq>DVLSQEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFADIDWEALKQKKIPPPFKPHLVSETDTSNFD</Hsp_hseq>
      <Hsp_midline>D L  + +  + GLL RNP  RLG      E++ H FF  +DW+ L ++K    F P L SE DTS FD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YPR111W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:747306:749000:1 gene:YPR111W transcript:YPR111W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF20 description:Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006315]</Hit_def>
  <Hit_accession>YPR111W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>127.872</Hsp_bit-score>
      <Hsp_score>320</Hsp_score>
      <Hsp_evalue>6.90676e-31</Hsp_evalue>
      <Hsp_query-from>471</Hsp_query-from>
      <Hsp_query-to>1079</Hsp_query-to>
      <Hsp_hit-from>109</Hsp_hit-from>
      <Hsp_hit-to>314</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>206</Hsp_align-len>
      <Hsp_qseq>DIPRYIISQLGLTRDPLEEMAQLSSCDS-GNPETPETDDATDSRAAESLPKK--KPCEEDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLS</Hsp_qseq>
      <Hsp_hseq>DMFDYVISRRQRTKQVLRYLEQQRSVKNVSNKVLNEEWALYLQREHEVLRKRRLKPKHKDFQILTQVGQGGYGQVYLAKKKDSDEICALKILNKKLLFKLNETNHVLTERDILTTTRSDWLVKLLYAFQDPESLYLAMEFVPGGDFRTLLINTRILKSGHARFYISEMFCAVNALHELGYTHRDLKPENFLIDATGHIKLTDFGLA</Hsp_hseq>
      <Hsp_midline>D+  Y+IS+   T+  L  + Q  S  +  N    E       R  E L K+  KP  +DF+ +  +  G YG VYL + K++ +  A+K +NK+ L   N+      ERDILT   + ++V +  +F+    L + ME+V GGD  TLL N   L    A+ Y +E   A+  LH  G  HRDLKP+N LI + GH+KLTDFGL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>129.413</Hsp_bit-score>
      <Hsp_score>324</Hsp_score>
      <Hsp_evalue>7.67364e-31</Hsp_evalue>
      <Hsp_query-from>636</Hsp_query-from>
      <Hsp_query-to>1079</Hsp_query-to>
      <Hsp_hit-from>322</Hsp_hit-from>
      <Hsp_hit-to>471</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>150</Hsp_align-len>
      <Hsp_qseq>EDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGA--LPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLS</Hsp_qseq>
      <Hsp_hseq>QSFEKIRLLGQGDVGKVYLVRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLS</Hsp_hseq>
      <Hsp_midline>+ FE I+L+  G  G VYLVR ++T Q FA+K +NK  +I R +I++   E++IL  +++PF+V ++ SF+TK +L + MEY  GG+    L+   +  +  + A+ Y +E V ALEYLH  G ++RDLKP+N+L+   GHV L+DF LS</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>120.939</Hsp_bit-score>
      <Hsp_score>302</Hsp_score>
      <Hsp_evalue>5.06682e-28</Hsp_evalue>
      <Hsp_query-from>636</Hsp_query-from>
      <Hsp_query-to>1079</Hsp_query-to>
      <Hsp_hit-from>494</Hsp_hit-from>
      <Hsp_hit-to>643</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>150</Hsp_align-len>
      <Hsp_qseq>EDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDC--ATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLS</Hsp_qseq>
      <Hsp_hseq>QSFEKIRLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDFDLS</Hsp_hseq>
      <Hsp_midline>+ FE I+L+  G  G V+LVR K+T + +A+K ++K  +I RN+I++   E++IL  + +PF+V ++ SF+++ +L + MEY  GG+   A   +    +  D A+ Y +E   ALEYLH  G ++RDLKP+N+L+   GH+ L+DF LS</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>116.316</Hsp_bit-score>
      <Hsp_score>290</Hsp_score>
      <Hsp_evalue>8.21958e-27</Hsp_evalue>
      <Hsp_query-from>618</Hsp_query-from>
      <Hsp_query-to>1091</Hsp_query-to>
      <Hsp_hit-from>338</Hsp_hit-from>
      <Hsp_hit-to>496</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>159</Hsp_align-len>
      <Hsp_qseq>KKKPCE-EDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKIGL</Hsp_qseq>
      <Hsp_hseq>RNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNM</Hsp_hseq>
      <Hsp_midline>+ KP   +DF+ +K+I  G++G V  VR K+T++ +A+K I K  ++ ++++     ER +L   + PF+V +  SF++   L  V+ ++ GG+    L+  G   +  A+ Y AE + AL+ LH   +V+RDLKP+N+L+   GH+ L DFGL K+ +</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>1.97737e-09</Hsp_evalue>
      <Hsp_query-from>1165</Hsp_query-from>
      <Hsp_query-to>1461</Hsp_query-to>
      <Hsp_hit-from>562</Hsp_hit-from>
      <Hsp_hit-to>658</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>101</Hsp_align-len>
      <Hsp_qseq>IVWPEGEDALPSDVQDLITGLLERNPLERLGTGGAFEVKQHQFFHSLDWDGLLRQK--AEFVPQLESEEDTSYFDTRSDRYHHLDSEDDTNDEEPLEMRQF</Hsp_qseq>
      <Hsp_hseq>LVFPDGFD---RDAKDLLIGLLSRDPTRRLGYNGADEIRNHPFFSQLSWKRLLMKGYIPPYKPAVSNSMDTSNFDEEFTREKPIDSVVDEYLSESVQ-KQF</Hsp_hseq>
      <Hsp_midline>+V+P+G D    D +DL+ GLL R+P  RLG  GA E++ H FF  L W  LL +     + P + +  DTS FD    R   +DS  D    E ++ +QF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>116.701</Hsp_bit-score>
      <Hsp_score>291</Hsp_score>
      <Hsp_evalue>1.31114e-26</Hsp_evalue>
      <Hsp_query-from>483</Hsp_query-from>
      <Hsp_query-to>1082</Hsp_query-to>
      <Hsp_hit-from>764</Hsp_hit-from>
      <Hsp_hit-to>972</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>121</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>213</Hsp_align-len>
      <Hsp_qseq>YIISQLGLTRDPLEEMAQLS--------SCDSGNPETPETDDATD--SRAAESLPKKKPCEEDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFA---ENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSK</Hsp_qseq>
      <Hsp_hseq>FQIEQDHASKEVLQETVSLAPTSTHASRTTDQQSPQKSQTSTSAKHKKRAAK---RRKVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQN-QRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCK</Hsp_hseq>
      <Hsp_midline>+ I Q   +++ L+E   L+        + D  +P+  +T  +     RAA+   ++K   ++F  +K++  G +G V L + K T +  A+K + K N+I  + I+ A  E+ +   A   ++PF+  ++CSF+T+  +   ME++ GGD    ++N   L V  A+ Y AE +LAL+Y H+ G+++RDLK +N+L+T  GH+K+ D+GL K</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>3.22663e-06</Hsp_evalue>
      <Hsp_query-from>1192</Hsp_query-from>
      <Hsp_query-to>1383</Hsp_query-to>
      <Hsp_hit-from>1047</Hsp_hit-from>
      <Hsp_hit-to>1114</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>25</Hsp_identity>
      <Hsp_positive>44</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>68</Hsp_align-len>
      <Hsp_qseq>LPSDVQDLITGLLERNPLERLGTG--GAFEVKQHQFFHSLDWDGLL--RQKAEFVPQLESEEDTSYFD</Hsp_qseq>
      <Hsp_hseq>MAGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFFRNINFDDILNLRVKPPYIPEIKSPEDTSYFE</Hsp_hseq>
      <Hsp_midline>+  ++  +  GLL ++P +RLG G   A EV +  FF ++++D +L  R K  ++P+++S EDTSYF+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>115.161</Hsp_bit-score>
      <Hsp_score>287</Hsp_score>
      <Hsp_evalue>4.40947e-26</Hsp_evalue>
      <Hsp_query-from>636</Hsp_query-from>
      <Hsp_query-to>1085</Hsp_query-to>
      <Hsp_hit-from>177</Hsp_hit-from>
      <Hsp_hit-to>327</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>151</Hsp_align-len>
      <Hsp_qseq>EDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAEN-PFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKI</Hsp_qseq>
      <Hsp_hseq>KDFKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKL</Hsp_hseq>
      <Hsp_midline>+DF+   +I +GAY  V L    +T++R+A K +NK+ LI + +++   +E+  L    N P VV +F +F+ +  L  ++EY   GD  +L+K  G+L    A+ Y A+ + A++YLH+ GI+HRD+KP+N+L+     +KLTDFG +K+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>114.005</Hsp_bit-score>
      <Hsp_score>284</Hsp_score>
      <Hsp_evalue>4.47831e-26</Hsp_evalue>
      <Hsp_query-from>618</Hsp_query-from>
      <Hsp_query-to>1091</Hsp_query-to>
      <Hsp_hit-from>335</Hsp_hit-from>
      <Hsp_hit-to>493</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>159</Hsp_align-len>
      <Hsp_qseq>KKKPCE-EDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKIGL</Hsp_qseq>
      <Hsp_hseq>KNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNM</Hsp_hseq>
      <Hsp_midline>K KP   +DF+ +K+I  G++G V  VR K+T++ +A+K + K  ++ + ++     ER +L   + PF+V +  SF++   L +V+ ++ GG+    L++ G   +  ++ Y AE + AL+ LH   +++RDLKP+N+L+   GH+ L DFGL K+ +</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>1.0185e-07</Hsp_evalue>
      <Hsp_query-from>1165</Hsp_query-from>
      <Hsp_query-to>1425</Hsp_query-to>
      <Hsp_hit-from>559</Hsp_hit-from>
      <Hsp_hit-to>644</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>89</Hsp_align-len>
      <Hsp_qseq>IVWPEGEDALPSDVQDLITGLLERNPLERLGTGGAFEVKQHQFFHSLDWDGLLRQK--AEFVPQLESEEDTSYFDTRSDRYHHLDSEDD</Hsp_qseq>
      <Hsp_hseq>LLFPDGFDPA---AKDLLIGLLSRDPSRRLGVNGTDEIRNHPFFKDISWKKLLLKGYIPPYKPIVKSEIDTANFDQEFTKEKPIDSVVD</Hsp_hseq>
      <Hsp_midline>+++P+G D      +DL+ GLL R+P  RLG  G  E++ H FF  + W  LL +     + P ++SE DT+ FD    +   +DS  D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>111.309</Hsp_bit-score>
      <Hsp_score>277</Hsp_score>
      <Hsp_evalue>1.22228e-25</Hsp_evalue>
      <Hsp_query-from>639</Hsp_query-from>
      <Hsp_query-to>1082</Hsp_query-to>
      <Hsp_hit-from>127</Hsp_hit-from>
      <Hsp_hit-to>300</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>174</Hsp_align-len>
      <Hsp_qseq>DFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLI--------------------------LRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSK</Hsp_qseq>
      <Hsp_hseq>DFKPVRVLGQGAYGKVLLVKDVNTSKLYAMKQLRKAEILISQTATDSKREDEDKNDGNNNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSK</Hsp_hseq>
      <Hsp_midline>DF+ ++++  GAYG V LV+   T + +AMK++ K  ++                          L  ++++ F ER IL+  E+P +V +F SF     L ++++Y+ GG+    LK  G L       Y AE   AL +LH  G+V+RDLKP+N L+   GH+ LTDFGLSK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.1301</Hsp_bit-score>
      <Hsp_score>235</Hsp_score>
      <Hsp_evalue>3.93485e-20</Hsp_evalue>
      <Hsp_query-from>636</Hsp_query-from>
      <Hsp_query-to>1085</Hsp_query-to>
      <Hsp_hit-from>123</Hsp_hit-from>
      <Hsp_hit-to>273</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>151</Hsp_align-len>
      <Hsp_qseq>EDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDIL-TFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKI</Hsp_qseq>
      <Hsp_hseq>KDFKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQKLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKI</Hsp_hseq>
      <Hsp_midline>+DF+  + + +G+Y +V L   +++ +++A+K ++K+ LI + +++   VE+  L        +  +F +F+ +  L  ++EY   GD   L+K  G+L    A+ Y ++ + A++ LHN GI+HRD+KP+N+L+     VKLTDFG +KI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.2041</Hsp_bit-score>
      <Hsp_score>230</Hsp_score>
      <Hsp_evalue>1.23009e-19</Hsp_evalue>
      <Hsp_query-from>639</Hsp_query-from>
      <Hsp_query-to>1085</Hsp_query-to>
      <Hsp_hit-from>54</Hsp_hit-from>
      <Hsp_hit-to>201</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>151</Hsp_align-len>
      <Hsp_qseq>DFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDI--LTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKI</Hsp_qseq>
      <Hsp_hseq>NYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKK--VLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNI</Hsp_hseq>
      <Hsp_midline>+++ +K +  G++G V L  H  T Q+ A+K INK+  +L     Q  +ER+I  L    +P ++ ++   ++K  + MV+EY  G +    +     +    A+ +F + + A+EY H + IVHRDLKP+NLL+    +VK+ DFGLS I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>91.2781</Hsp_bit-score>
      <Hsp_score>225</Hsp_score>
      <Hsp_evalue>8.02128e-19</Hsp_evalue>
      <Hsp_query-from>669</Hsp_query-from>
      <Hsp_query-to>1085</Hsp_query-to>
      <Hsp_hit-from>30</Hsp_hit-from>
      <Hsp_hit-to>176</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>149</Hsp_align-len>
      <Hsp_qseq>GAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAF--------VERDI--LTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKI</Hsp_qseq>
      <Hsp_hseq>GSTGKVQLAQHERTGHRTAVKVISKS--IFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAAL</Hsp_hseq>
      <Hsp_midline>G+ G V L +H+ T  R A+K I+K   I  N    +         +ER+I  +    +P V+ ++  +ET  +L +++EY E G+   LL + G LP   A   F + ++ + Y H  GIVHRDLKP+NLL+ S  ++K+ DFG++ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.0409</Hsp_bit-score>
      <Hsp_score>214</Hsp_score>
      <Hsp_evalue>2.39762e-18</Hsp_evalue>
      <Hsp_query-from>438</Hsp_query-from>
      <Hsp_query-to>1088</Hsp_query-to>
      <Hsp_hit-from>36</Hsp_hit-from>
      <Hsp_hit-to>252</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>221</Hsp_align-len>
      <Hsp_qseq>GHAKEDQGIKSDIPRYIISQLGLTRDPLEEMAQLSSCDSGNPETPETDDATDSRAA---ESLPKKKPCE-EDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKIG</Hsp_qseq>
      <Hsp_hseq>SHSPQQRNPNSKIPSPVREKLN--RLPVNNKKFLDMESSKIPSP--IRKATSSKMIHENKKLPKFKSLSLDDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIIN</Hsp_hseq>
      <Hsp_midline> H+ + +   S IP  +  +L   R P+     L    S  P       AT S+     + LPK K    +DFE  K +  G +G VY VRH+ T    A+K + K+ +I  N  +Q   E +I T   +P +   +  F  ++ + ++MEY+  G+   LL+  G     +A  Y  +   AL+Y+H   I+HRD+KP+N+LI     +KLTDFG S I </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.1965</Hsp_bit-score>
      <Hsp_score>217</Hsp_score>
      <Hsp_evalue>5.58088e-18</Hsp_evalue>
      <Hsp_query-from>588</Hsp_query-from>
      <Hsp_query-to>1085</Hsp_query-to>
      <Hsp_hit-from>179</Hsp_hit-from>
      <Hsp_hit-to>345</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>169</Hsp_align-len>
      <Hsp_qseq>TDSRAAESLPKKKPCEEDFETI-KLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGH--VKLTDFGLSKI</Hsp_qseq>
      <Hsp_hseq>TSSTASSMVANKTGIFKDFSIIDEVVGQGAFATVKKAIERTTGKTFAVKIISKRKVI--GNMDGVTRELEVLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKV</Hsp_hseq>
      <Hsp_midline>T S A+  +  K    +DF  I +++  GA+  V     + T + FA+K I+K+ +I    +     E ++L    +P +V +   +E      MVME+V GGD    +   GA+  D  +    + + A++Y+H+ GI HRDLKPDN+LI       VK+TDFGL+K+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.1149</Hsp_bit-score>
      <Hsp_score>209</Hsp_score>
      <Hsp_evalue>6.81421e-17</Hsp_evalue>
      <Hsp_query-from>669</Hsp_query-from>
      <Hsp_query-to>1079</Hsp_query-to>
      <Hsp_hit-from>28</Hsp_hit-from>
      <Hsp_hit-to>178</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>151</Hsp_align-len>
      <Hsp_qseq>GAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFV------------ERDILTFA--ENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLS</Hsp_qseq>
      <Hsp_hseq>GSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMA</Hsp_hseq>
      <Hsp_midline>G+ G V L R+  T Q  A+K I+K      N    + V            ER+I+      +P V+ ++  +ET   L +V+EY E G+   LL   G LP   A  +F + ++ + Y H  GIVHRDLKP+NLL+    ++K+ DFG++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.2629</Hsp_bit-score>
      <Hsp_score>199</Hsp_score>
      <Hsp_evalue>8.29754e-16</Hsp_evalue>
      <Hsp_query-from>621</Hsp_query-from>
      <Hsp_query-to>1073</Hsp_query-to>
      <Hsp_hit-from>4</Hsp_hit-from>
      <Hsp_hit-to>158</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>155</Hsp_align-len>
      <Hsp_qseq>KKPCEEDFETIKLISNGAYGAVYLVRHKETRQR-FAMKKINKQNLILRNQIQQAFVERDILTF---AENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFG</Hsp_qseq>
      <Hsp_hseq>RKRSPHDFIFKEELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFG</Hsp_hseq>
      <Hsp_midline>+K    DF   + + +G+Y  V+    K++  + +A+K  +K+++I   +++   +E++ +       +  ++ ++ +F  + +L  V+++  GG+  +LL  +G       + + A+ + ALE++H++GI+HRDLKP+N+L+   G + +TDFG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.8777</Hsp_bit-score>
      <Hsp_score>198</Hsp_score>
      <Hsp_evalue>1.26707e-15</Hsp_evalue>
      <Hsp_query-from>639</Hsp_query-from>
      <Hsp_query-to>1085</Hsp_query-to>
      <Hsp_hit-from>98</Hsp_hit-from>
      <Hsp_hit-to>272</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>175</Hsp_align-len>
      <Hsp_qseq>DFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQN------------------LILRNQIQQAFVERDILTFAE--------NPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKI</Hsp_qseq>
      <Hsp_hseq>DWEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESEILERQKRLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNI</Hsp_hseq>
      <Hsp_midline>D+E ++ +  G+ G V LV+H++T++   +K +N+ +                  ++ R +  +  + RD  T  E        +P +  +F       H  M+ EYV GG     +   G+L    A+ +      AL+YLH   IVHRDLK +N++I+S G +K+ DFGLS I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.7221</Hsp_bit-score>
      <Hsp_score>195</Hsp_score>
      <Hsp_evalue>2.32113e-15</Hsp_evalue>
      <Hsp_query-from>660</Hsp_query-from>
      <Hsp_query-to>1076</Hsp_query-to>
      <Hsp_hit-from>626</Hsp_hit-from>
      <Hsp_hit-to>760</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>148</Hsp_align-len>
      <Hsp_qseq>ISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTF--AENPFVVGMFCSFETKRHLCMVMEYVEGGD-------CATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGL</Hsp_qseq>
      <Hsp_hseq>IGQGASGGVYTAYEIGTNVSVAIKQMN-----LEKQPKKELIINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVTHCILTEGQIGAV--------CRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGF</Hsp_hseq>
      <Hsp_midline>I  GA G VY      T    A+K++N     L  Q ++  +  +IL    +++P +V    S+  K  L ++MEY+EGG        C      +GA+          ET+  LE+LH+ G++HRD+K DN+L++  G +KLTDFG </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.7221</Hsp_bit-score>
      <Hsp_score>195</Hsp_score>
      <Hsp_evalue>2.69346e-15</Hsp_evalue>
      <Hsp_query-from>522</Hsp_query-from>
      <Hsp_query-to>1085</Hsp_query-to>
      <Hsp_hit-from>78</Hsp_hit-from>
      <Hsp_hit-to>293</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>216</Hsp_align-len>
      <Hsp_qseq>EEMAQLSSCDSGNPETPETDDATDSRAAESLPKK--KPCEEDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINK------------------QNLILRNQIQQAFVERDILTFAE--------NPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKI</Hsp_qseq>
      <Hsp_hseq>ERQVELEGKSRENAPKPNTTSQSRVSSSQGMPKQFHRKSLGDWEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPPPKNEQDVLERQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNI</Hsp_hseq>
      <Hsp_midline>E   +L      N   P T   +   +++ +PK+  +    D+E ++ +  G+ G V L +H+ T +  A+K +N+                  Q+++ R +  +  + RD  T  E        +P +  +F       H  M+ EYV GG     +   G++    A+ +      AL YLH   IVHRDLK +N++I+    +K+ DFGLS I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.0258</Hsp_bit-score>
      <Hsp_score>188</Hsp_score>
      <Hsp_evalue>8.22287e-15</Hsp_evalue>
      <Hsp_query-from>633</Hsp_query-from>
      <Hsp_query-to>1145</Hsp_query-to>
      <Hsp_hit-from>211</Hsp_hit-from>
      <Hsp_hit-to>380</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>178</Hsp_align-len>
      <Hsp_qseq>EEDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVV---GMFCSFETKRHLCMVMEYVEGGDCATLLKNL---GALPVDMAQLYFAETVL-ALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKIGLMSLTTNLAALVTLSATVF</Hsp_qseq>
      <Hsp_hseq>KDEITTLGILGEGAGGSVAKCRLKNGKKVFALKTINTMNTDPEYQ-KQIFRELQFNKSFKSDYIVQYYGMFTD-EQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFGVSGEAVNSLA------MTFTGTSF</Hsp_hseq>
      <Hsp_midline>+++  T+ ++  GA G+V   R K  ++ FA+K IN  N     Q +Q F E       ++ ++V   GMF   E    + + MEY+ G       KNL   G    +      AE+VL  L YLH   ++HRD+KP N+L+   G +KL DFG+S   + SL       +T + T F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.8702</Hsp_bit-score>
      <Hsp_score>185</Hsp_score>
      <Hsp_evalue>2.39242e-14</Hsp_evalue>
      <Hsp_query-from>633</Hsp_query-from>
      <Hsp_query-to>1118</Hsp_query-to>
      <Hsp_hit-from>218</Hsp_hit-from>
      <Hsp_hit-to>384</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>169</Hsp_align-len>
      <Hsp_qseq>EEDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVV---GMFCSFETKRHLCMVMEYVEGGDCATLLKNL---GALPVDMAQLYFAETVL-ALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKIGLMSLTTNLAA</Hsp_qseq>
      <Hsp_hseq>KDRIETLGILGEGAGGSVSKCKLKNGSKIFALKVINTLNTDPEYQ-KQIFRELQFNRSFQSEYIVRYYGMFTDDENS-SIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVSGEAVNSLATTFTG</Hsp_hseq>
      <Hsp_midline>++  ET+ ++  GA G+V   + K   + FA+K IN  N     Q +Q F E       ++ ++V   GMF   E    + + MEY+ G     + KNL   G    +      AE VL  L YLH   ++HRD+KP N+L+   G VKL DFG+S   + SL T    </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.485</Hsp_bit-score>
      <Hsp_score>184</Hsp_score>
      <Hsp_evalue>5.65075e-14</Hsp_evalue>
      <Hsp_query-from>657</Hsp_query-from>
      <Hsp_query-to>1082</Hsp_query-to>
      <Hsp_hit-from>1180</Hsp_hit-from>
      <Hsp_hit-to>1326</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>148</Hsp_align-len>
      <Hsp_qseq>LISNGAYGAVYLVRHKETRQRFAMKKI-----NKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHL-CMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSK</Hsp_qseq>
      <Hsp_hseq>MIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIV-QYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISR</Hsp_hseq>
      <Hsp_midline>+I  G++GAVYL  +  T +  A+K++     + QN  + + ++    E   L   ++  +V  +  FE K ++  + +EYV GG   +L++  G     + +    + +  L YLH+ GI+HRD+K DNLL+   G  K++DFG+S+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.7146</Hsp_bit-score>
      <Hsp_score>182</Hsp_score>
      <Hsp_evalue>6.3245e-14</Hsp_evalue>
      <Hsp_query-from>846</Hsp_query-from>
      <Hsp_query-to>1112</Hsp_query-to>
      <Hsp_hit-from>394</Hsp_hit-from>
      <Hsp_hit-to>482</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>89</Hsp_align-len>
      <Hsp_qseq>ETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKIGLMSLTTNL</Hsp_qseq>
      <Hsp_hseq>DAKGEYCEVMEYCAGGDLFTLVVAAGKLEYMEADCFFKQLIRGVVYMHEMGVCHRDLKPENLLLTHDGVLKITDFGNSECFKMAWEKNI</Hsp_hseq>
      <Hsp_midline>+ K   C VMEY  GGD  TL+   G L    A  +F + +  + Y+H  G+ HRDLKP+NLL+T  G +K+TDFG S+   M+   N+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.0998</Hsp_bit-score>
      <Hsp_score>183</Hsp_score>
      <Hsp_evalue>8.05789e-14</Hsp_evalue>
      <Hsp_query-from>642</Hsp_query-from>
      <Hsp_query-to>1082</Hsp_query-to>
      <Hsp_hit-from>1266</Hsp_hit-from>
      <Hsp_hit-to>1413</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>152</Hsp_align-len>
      <Hsp_qseq>FETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFV----ERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDM-AQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSK</Hsp_qseq>
      <Hsp_hseq>WQKRNFIGGGTFGRVYSAVDLDNGEILAVKEINIQD---SKSMQKIFPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAALLEH-GRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAK</Hsp_hseq>
      <Hsp_midline>++    I  G +G VY     +  +  A+K+IN Q+      +Q+ F     E  +L    +P +V  +     +  + + MEY EGG  A LL++ G +  +M  Q+Y  + +  L YLH  GIVHRD+KP+N+L+   G +K  DFG +K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.9442</Hsp_bit-score>
      <Hsp_score>180</Hsp_score>
      <Hsp_evalue>9.14425e-14</Hsp_evalue>
      <Hsp_query-from>609</Hsp_query-from>
      <Hsp_query-to>1079</Hsp_query-to>
      <Hsp_hit-from>7</Hsp_hit-from>
      <Hsp_hit-to>163</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>161</Hsp_align-len>
      <Hsp_qseq>SLPKKKPCEEDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAE--NPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKN--LGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLS</Hsp_qseq>
      <Hsp_hseq>SIRSRTPPSKLYSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEH----SDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVS</Hsp_hseq>
      <Hsp_midline>S+  + P  + +     I  G +G VY    + T++  A+K +N ++    +      + ++I   AE  +P +     +      + +VMEY  GG C+ LLK   +  LP +       E  L L+YLH    +HRD+K  N+L+   G VKL DFG+S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>8.32129e-13</Hsp_evalue>
      <Hsp_query-from>657</Hsp_query-from>
      <Hsp_query-to>1121</Hsp_query-to>
      <Hsp_hit-from>1039</Hsp_hit-from>
      <Hsp_hit-to>1196</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>159</Hsp_align-len>
      <Hsp_qseq>LISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVER-DILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMA-QLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSK--IGLMSLTTNLAAL</Hsp_qseq>
      <Hsp_hseq>FIGGGTFGQVYSAINLENGEILAVKEIKIHDTTTMKKIFPLIKEEMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEYCEGGSLASLLDH-GRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAV</Hsp_hseq>
      <Hsp_midline> I  G +G VY   + E  +  A+K+I   +     +I     E   +L    +P +V  +     +  + + MEY EGG  A+LL + G +  +M  Q+Y  E +  L YLH  G+VHRD+KP+N+L+   G +K  DFG ++  +G  + T   AA+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.3218</Hsp_bit-score>
      <Hsp_score>168</Hsp_score>
      <Hsp_evalue>1.02458e-12</Hsp_evalue>
      <Hsp_query-from>639</Hsp_query-from>
      <Hsp_query-to>1085</Hsp_query-to>
      <Hsp_hit-from>12</Hsp_hit-from>
      <Hsp_hit-to>161</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>156</Hsp_align-len>
      <Hsp_qseq>DFETIKLISNGAYGAVYLVRHKETRQRFAMKKI---NKQNLILRN----QIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKI</Hsp_qseq>
      <Hsp_hseq>DFQLKSLLGEGAYGVVCSATHKPTGEIVAIKKIEPFDKPLFALRTLREIKILKHFKHENIITI----FNIQRPDSFENFNEVYIIQELMQTDLHRVISTQM--LSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARI</Hsp_hseq>
      <Hsp_midline>DF+   L+  GAYG V    HK T +  A+KKI   +K    LR     +I + F   +I+T     F +    SFE    + ++ E ++      +   +  L  D  Q +  +T+ A++ LH   ++HRDLKP NLLI S   +K+ DFGL++I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>1.06187e-12</Hsp_evalue>
      <Hsp_query-from>654</Hsp_query-from>
      <Hsp_query-to>1085</Hsp_query-to>
      <Hsp_hit-from>29</Hsp_hit-from>
      <Hsp_hit-to>170</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>145</Hsp_align-len>
      <Hsp_qseq>KLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLL-KNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKI</Hsp_qseq>
      <Hsp_hseq>QVIGRGSYGVVYKAINKHTDQVVAIKEVVYEN---DEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTI</Hsp_hseq>
      <Hsp_midline>++I  G+YG VY   +K T Q  A+K++  +N     ++     E  +L    +  +V           L +++EY   G    L+ ++   L  + ++ Y  +T+L L+YLH  G++HRD+K  N+L+++   VKL DFG+S I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>2.43321e-12</Hsp_evalue>
      <Hsp_query-from>783</Hsp_query-from>
      <Hsp_query-to>1091</Hsp_query-to>
      <Hsp_hit-from>161</Hsp_hit-from>
      <Hsp_hit-to>266</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>106</Hsp_align-len>
      <Hsp_qseq>VERDI--LTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMG-HVKLTDFGLSKIGL</Hsp_qseq>
      <Hsp_hseq>IEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALEL</Hsp_hseq>
      <Hsp_midline>+ER+I  +    +  V+ +F  +E K  L +V+EYV+GG+    L + G LP   A  YF + V  + Y H++ I HRDLKP+NLL+      +K+ DFG++ + L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>2.55571e-12</Hsp_evalue>
      <Hsp_query-from>513</Hsp_query-from>
      <Hsp_query-to>1145</Hsp_query-to>
      <Hsp_hit-from>374</Hsp_hit-from>
      <Hsp_hit-to>622</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>252</Hsp_align-len>
      <Hsp_qseq>DPLEEMAQLSSCDSGNPETPETDDATDSRAAESLPKKKPCEEDFETIKLISNGAYGAVYLVRHKETRQRFAMKKI-------------NKQ----------------------------NLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKIGLMSLTTNLAALVTLSATVF</Hsp_qseq>
      <Hsp_hseq>DAISNQLELLSVESGEEE--DHDFFGEDSDIVSLPTKIATPKNWLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISK-KLSPLNKKQNKRASLQGSVF</Hsp_hseq>
      <Hsp_midline>D +    +L S +SG  E  + D   +     SLP K    +++     I +G++G+VYL  +  T +  A+K++             NKQ                              I R  +     E ++L    +  +V  + + +   +L + +EYV GG  +++L N G     +   +  + ++ + YLH   I+HRD+K  N+LI   G VK+TDFG+SK  L  L        +L  +VF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>4.3516e-12</Hsp_evalue>
      <Hsp_query-from>642</Hsp_query-from>
      <Hsp_query-to>1145</Hsp_query-to>
      <Hsp_hit-from>360</Hsp_hit-from>
      <Hsp_hit-to>547</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>200</Hsp_align-len>
      <Hsp_qseq>FETIKLISNGAYGAVYLVR-----------------HKETRQRFAMKKIN-----KQNLILRNQ-IQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLL-----KNLG--ALPVDMAQLYF--AETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKIGLMSLTTNLAALVTLSATVF</Hsp_qseq>
      <Hsp_hseq>FQLVEKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQPKKQLIMNELLVMNDSRQENIVNFLE-AYIID-------DEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGF----CVELTEKRSKRATMVGTPY</Hsp_hseq>
      <Hsp_midline>F+ ++    GA GAVYL +                 H+   +R A+K+I      K+ LI+    +     + +I+ F E  +++           L ++MEY+EGG    +L      N G  + P++  Q+ +   ET   L++LHN  I+HRD+K DN+L+ S G VK+TDFG      + LT   +   T+  T +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>5.35851e-12</Hsp_evalue>
      <Hsp_query-from>639</Hsp_query-from>
      <Hsp_query-to>1082</Hsp_query-to>
      <Hsp_hit-from>40</Hsp_hit-from>
      <Hsp_hit-to>180</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>148</Hsp_align-len>
      <Hsp_qseq>DFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSK</Hsp_qseq>
      <Hsp_hseq>NYKILKQIGEGSFGKVYLALHRPTHRKVCLKTSDKNDP---NIVREVFYHRQF----DFPYITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTR</Hsp_hseq>
      <Hsp_midline>+++ +K I  G++G VYL  H+ T ++  +K  +K +    N +++ F  R      + P++  ++    T+  + M +EY  G +    L +L  + +      FA+   A+ Y H+   VHRDLK +N+L+   G+ KLTDFG ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>6.76919e-12</Hsp_evalue>
      <Hsp_query-from>651</Hsp_query-from>
      <Hsp_query-to>1082</Hsp_query-to>
      <Hsp_hit-from>186</Hsp_hit-from>
      <Hsp_hit-to>329</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>152</Hsp_align-len>
      <Hsp_qseq>IKLISNGAYGAVYLVRHKETRQRFAMKKINKQN--------LILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSK</Hsp_qseq>
      <Hsp_hseq>IMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNVSTIKE--------IMVESQKTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLAR</Hsp_hseq>
      <Hsp_midline>I  +  G YG VY  ++  T +  A+KK+  Q          I   ++ Q+F   ++ T  E           E+++ + M+ EY +      LL     +     +  F + +L +EYLH+  I+HRD+K  N+LI + G++K+TDFGL++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>9.3063e-12</Hsp_evalue>
      <Hsp_query-from>573</Hsp_query-from>
      <Hsp_query-to>1082</Hsp_query-to>
      <Hsp_hit-from>14</Hsp_hit-from>
      <Hsp_hit-to>187</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>174</Hsp_align-len>
      <Hsp_qseq>ETDDATDSRAAESLPKKKPCEEDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRN-QIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLI---TSMGHVKLTDFGLSK</Hsp_qseq>
      <Hsp_hseq>QTEEDSEGKMAHVQPASYVNKKKYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAK</Hsp_hseq>
      <Hsp_midline>+T++ ++ + A   P     ++ +   K +  G +G V   ++ ET +  A+K + K+ L     Q++  + E DIL    +P +V     FE+K    ++ +  +GG+    +   G    + A     E + A++Y+H+  IVHRDLKP+NLL    +    + + DFG++K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>1.06954e-11</Hsp_evalue>
      <Hsp_query-from>867</Hsp_query-from>
      <Hsp_query-to>1154</Hsp_query-to>
      <Hsp_hit-from>158</Hsp_hit-from>
      <Hsp_hit-to>255</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>99</Hsp_align-len>
      <Hsp_qseq>MVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVL--ALEYLHNYGIVHRDLKPDNLLITSMGH-VKLTDFGLSKIGLMSLTTNLAALVTLSATVFDTT</Hsp_qseq>
      <Hsp_hseq>IIMEYCSGGDLYEAIK-ADAVPKKTKSITHIITQIMDAIEYVHNKGIYHRDIKPENILISGIDWTIKLTDWGLATTDKTSMDRNVGSERYMSPELFDSN</Hsp_hseq>
      <Hsp_midline>++MEY  GGD    +K   A+P     +    T +  A+EY+HN GI HRD+KP+N+LI+ +   +KLTD+GL+     S+  N+ +   +S  +FD+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>1.13757e-11</Hsp_evalue>
      <Hsp_query-from>576</Hsp_query-from>
      <Hsp_query-to>1118</Hsp_query-to>
      <Hsp_hit-from>176</Hsp_hit-from>
      <Hsp_hit-to>383</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>208</Hsp_align-len>
      <Hsp_qseq>TDDATDSRAAESLPKKKPCE--EDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSF-----ETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLIT----------SMG---------HVKLTDFGLSKI-GLMSLTTNLAA</Hsp_qseq>
      <Hsp_hseq>SQNATTSAAIRKLNKTRPVSFFDKYLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCG</Hsp_hseq>
      <Hsp_midline>+ +AT S A   L K +P    + +   K +  G Y  V   ++K+T Q+ A+K  + Q    + + +Q   E +IL   ++P +V +  SF     +++    +V+E ++ G+    +     L  D ++  F + +  L+YLH   I+HRD+KP+N+L+            +G          VK+ DFGL+K  G M  T  L  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>1.27867e-11</Hsp_evalue>
      <Hsp_query-from>807</Hsp_query-from>
      <Hsp_query-to>1079</Hsp_query-to>
      <Hsp_hit-from>73</Hsp_hit-from>
      <Hsp_hit-to>164</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>92</Hsp_align-len>
      <Hsp_qseq>AENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLH-NYGIVHRDLKPDNLLITSMGHVKLTDFGLS</Hsp_qseq>
      <Hsp_hseq>SKHPNVLRLIDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGLA</Hsp_hseq>
      <Hsp_midline>+++P V+ +     +K ++ +++E  +GGD    ++    +  D+AQ YF + V A+ YLH   G+ HRD+KP+N+L+   G++KL DFGL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>1.536e-11</Hsp_evalue>
      <Hsp_query-from>639</Hsp_query-from>
      <Hsp_query-to>1079</Hsp_query-to>
      <Hsp_hit-from>49</Hsp_hit-from>
      <Hsp_hit-to>211</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>165</Hsp_align-len>
      <Hsp_qseq>DFETIKLISNGAYGAVYLVRHKETRQRFAMKKINK------QNLILRNQIQQAFVERDILTFAENPFVVGMFCSF----ETKRHLCMVMEYVEGGDCATL------LKNLGA--LPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLS</Hsp_qseq>
      <Hsp_hseq>NFEILATLGNGQYGKVKLARDLGTGALVAIKILNRFEKRSGYSLQLKVENPRVNQEIEVMKRCHHENVVELYEILNDPESTKVYL--VLEYCSRGPVKWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVA</Hsp_hseq>
      <Hsp_midline>+FE +  + NG YG V L R   T    A+K +N+       +L L+ +  +   E +++    +  VV ++        TK +L  V+EY   G           +K +G   L    ++    + V  LEYLH+ GI HRD+KP NLLI+S G VK++DFG++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>4.28125e-11</Hsp_evalue>
      <Hsp_query-from>636</Hsp_query-from>
      <Hsp_query-to>1115</Hsp_query-to>
      <Hsp_hit-from>358</Hsp_hit-from>
      <Hsp_hit-to>521</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>170</Hsp_align-len>
      <Hsp_qseq>EDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLL---KNLGALPVDMAQLYF-AETVL----ALEYLHNYGIVHRDLKPDNLLITS-MGHVKLTDFGLSKIGLMSLT-TNLA</Hsp_qseq>
      <Hsp_hseq>DELEFLDELGHGNYGNVSKVLHKPTNVIMATKEVRLE--LDEAKFRQILMELEVLHKCNSPYIVDFYGAFFIEGAVYMCMEYMDGGSLDKIYDESSEIGG--IDEPQLAFIANAVIHGLKELKEQHN--IIHRDVKPTNILCSANQGTVKLCDFGVSGNLVASLAKTNIG</Hsp_hseq>
      <Hsp_midline>++ E +  + +G YG V  V HK T    A K++  +  +   + +Q  +E ++L    +P++V  + +F  +  + M MEY++GG    +      +G   +D  QL F A  V+     L+  HN  I+HRD+KP N+L ++  G VKL DFG+S   + SL  TN+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>4.58044e-11</Hsp_evalue>
      <Hsp_query-from>639</Hsp_query-from>
      <Hsp_query-to>1073</Hsp_query-to>
      <Hsp_hit-from>1095</Hsp_hit-from>
      <Hsp_hit-to>1250</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>164</Hsp_align-len>
      <Hsp_qseq>DFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRH--LCMVMEYVEGGD-------------CATLLKNLGALPVDM----AQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFG</Hsp_qseq>
      <Hsp_hseq>DFVSLQKMGEGAYGKVNLCIHKKNRYIVVIKMIFKERILVDTWVR----DRKLGTI---PSEIQIMATLNKKPHENILRLLDFFEDDDYYYIETPVHGETGCIDLF-DLIEFKTNMTEFEAKLIFKQVVAGIKHLHDQGIVHRDIKDENVIVDSKGFVKIIDFG</Hsp_hseq>
      <Hsp_midline>DF +++ +  GAYG V L  HK+ R    +K I K+ +++   ++    +R + T    P  + +  +   K H  +  ++++ E  D             C  L  +L     +M    A+L F + V  +++LH+ GIVHRD+K +N+++ S G VK+ DFG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>7.7587e-11</Hsp_evalue>
      <Hsp_query-from>642</Hsp_query-from>
      <Hsp_query-to>1079</Hsp_query-to>
      <Hsp_hit-from>133</Hsp_hit-from>
      <Hsp_hit-to>299</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>167</Hsp_align-len>
      <Hsp_qseq>FETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQ--------NLILRNQIQQA-FVERDILTFAE--NPFVVGMFCSFE--TKRHLCMVMEYVEGG-------DC-ATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLS</Hsp_qseq>
      <Hsp_hseq>YEIIKELGHGQHGKVKLARDILSKQLVAIKIVDRHEKKQRKFFTFIKSSKISENDKIKREIAIMKKCHHKHVVQLIEVLDDLKSRKIYLVLEYCSRGEVKWCPPDCMESDAKGPSLLSFQETREILRGVVLGLEYLHYQGIIHRDIKPANLLISGDGTVKISDFGVS</Hsp_hseq>
      <Hsp_midline>+E IK + +G +G V L R   ++Q  A+K +++           I  ++I +   ++R+I    +  +  VV +    +    R + +V+EY   G       DC  +  K    L     +      VL LEYLH  GI+HRD+KP NLLI+  G VK++DFG+S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>1.41068e-10</Hsp_evalue>
      <Hsp_query-from>642</Hsp_query-from>
      <Hsp_query-to>1076</Hsp_query-to>
      <Hsp_hit-from>546</Hsp_hit-from>
      <Hsp_hit-to>714</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>169</Hsp_align-len>
      <Hsp_qseq>FETIKLISNGAYGAVYLVRHKETRQRFAM--------------KKINKQNLILRNQIQQAFVERDILTFAENPF--VVGMFCSF-ETKRHLCMVMEYVEGGDCATLLKNLGA-----LPVDMAQLYF--AETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGL</Hsp_qseq>
      <Hsp_hseq>FKVIEKAGQGASGSVYLAERTHIPTESNMIELINNDIDEPHVGDKVAIKQMVLSKQPRKELIVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGF</Hsp_hseq>
      <Hsp_midline>F+ I+    GA G+VYL           M               K+  + ++L  Q ++  +  +IL   ++    +V    ++  T   L +VME++EGG    +++N         P+   Q+ +   ET   L++LH+  I+HRD+K DN+L+ +   VK+TDFG </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>1.73796e-10</Hsp_evalue>
      <Hsp_query-from>642</Hsp_query-from>
      <Hsp_query-to>1130</Hsp_query-to>
      <Hsp_hit-from>7</Hsp_hit-from>
      <Hsp_hit-to>172</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>168</Hsp_align-len>
      <Hsp_qseq>FETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGG-----DCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKIGLMSLTTNLAALVTL</Hsp_qseq>
      <Hsp_hseq>FKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSE--EGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTL</Hsp_hseq>
      <Hsp_midline>F+ ++ + NG Y  VY   +K T    A+K++   +         A  E  ++   ++  +V ++    T+  L +V E+++       D  T+      L +++ + +  + +  L + H   I+HRDLKP NLLI   G +KL DFGL++   + + T  + +VTL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>2.71466e-10</Hsp_evalue>
      <Hsp_query-from>654</Hsp_query-from>
      <Hsp_query-to>1082</Hsp_query-to>
      <Hsp_hit-from>51</Hsp_hit-from>
      <Hsp_hit-to>197</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>148</Hsp_align-len>
      <Hsp_qseq>KLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRN-QIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALP-VDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGH---VKLTDFGLSK</Hsp_qseq>
      <Hsp_hseq>RTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEI-IVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAK</Hsp_hseq>
      <Hsp_midline>+ +  G++G V   R   T +  A+K + K+ L   N Q+Q  + E  IL    +P +V     FE+K    +V +   GG+    + + G    VD  ++   + + A+EY+H+  +VHRDLKP+N+L         + + DFG++K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>4.00209e-10</Hsp_evalue>
      <Hsp_query-from>642</Hsp_query-from>
      <Hsp_query-to>1079</Hsp_query-to>
      <Hsp_hit-from>23</Hsp_hit-from>
      <Hsp_hit-to>166</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>149</Hsp_align-len>
      <Hsp_qseq>FETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDI---LTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLS</Hsp_qseq>
      <Hsp_hseq>FKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLN----LDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLR-PGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVA</Hsp_hseq>
      <Hsp_midline>F+  ++I  G +G VY   + +T + +A+K +N    +  +  +   V+R+I    +  +   +   + S+     L ++ME+  GG   +LL+  G +      +   E ++AL+ +H   ++HRD+K  N+LIT+ G+VKL DFG++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>4.81001e-10</Hsp_evalue>
      <Hsp_query-from>642</Hsp_query-from>
      <Hsp_query-to>1073</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>153</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>153</Hsp_align-len>
      <Hsp_qseq>FETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLL---KNLGA------LPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFG</Hsp_qseq>
      <Hsp_hseq>YTKLRSIQSGTFSTVYKAWSTTHNRYVALKITPKYKTSEANMKNEYDVMKILSSCNPHPNICSMLDFYTDDSYYIMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQIDMQKI-IKQLCSAISFAHSLGIAHRDIKPENILLTINGDIKLADWG</Hsp_hseq>
      <Hsp_midline>+  ++ I +G +  VY        +  A+K   K      N   +  V + + +   +P +  M   +    +  MV+EY E GD    L   K+ G+      + +DM ++   +   A+ + H+ GI HRD+KP+N+L+T  G +KL D+G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>2.05987e-09</Hsp_evalue>
      <Hsp_query-from>654</Hsp_query-from>
      <Hsp_query-to>1082</Hsp_query-to>
      <Hsp_hit-from>11</Hsp_hit-from>
      <Hsp_hit-to>152</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>145</Hsp_align-len>
      <Hsp_qseq>KLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGAL--PVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSK</Hsp_qseq>
      <Hsp_hseq>KKVGEGTYAVVYLGCQHSTGRKIAIKEI-KTSEFKDGLDMSAIREVKYLQEMQHPNVIELIDIFMAYDNLNLVLEFLPT-DLEVVIKDKSILFTPADI-KAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLAR</Hsp_hseq>
      <Hsp_midline>K +  G Y  VYL     T ++ A+K+I K +         A  E   L   ++P V+ +   F    +L +V+E++   D   ++K+   L  P D+ + +   T+  + + H   I+HRDLKP+NLL +  G +K+ DFGL++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>3.13428e-09</Hsp_evalue>
      <Hsp_query-from>642</Hsp_query-from>
      <Hsp_query-to>1082</Hsp_query-to>
      <Hsp_hit-from>13</Hsp_hit-from>
      <Hsp_hit-to>166</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>158</Hsp_align-len>
      <Hsp_qseq>FETIKLISNGAYGAVYLVRHKETRQRFAMKKIN--KQNLILRNQIQQAFVERDILTFAENPFVVGMF-----CSFETKRHLCMVMEYVEGGDCATLLKN----LGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSK</Hsp_qseq>
      <Hsp_hseq>YKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRTIREIKLLR---YFHEHENIISILDKVRPVSIDKLNAVYLVEELMET-DLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLAR</Hsp_hseq>
      <Hsp_midline>++ + LI  GAYG V    HK +  + A+KKI    + L +   I++  + R    F E+  ++ +       S +    + +V E +E  D   ++ N       L  D  Q +  + + AL+ +H+  ++HRD+KP NLL+ S   +K+ DFGL++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>3.19701e-09</Hsp_evalue>
      <Hsp_query-from>639</Hsp_query-from>
      <Hsp_query-to>1073</Hsp_query-to>
      <Hsp_hit-from>840</Hsp_hit-from>
      <Hsp_hit-to>995</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>161</Hsp_align-len>
      <Hsp_qseq>DFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATL------------LKNLGALPVDM----AQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFG</Hsp_qseq>
      <Hsp_hseq>DFTILQVMGEGAYGKVNLCIHNREHYIVVIKMIFKERILVDTWVR----DRKLGTIPSEIQIMATLNK-NSQENILKLLDFFEDDDYYYIETPVHGETGSIDLFDVIEFKKDMVEHEAKLVFKQVVASIKHLHDQGIVHRDIKDENVIVDSHGFVKLIDFG</Hsp_hseq>
      <Hsp_midline>DF  ++++  GAYG V L  H        +K I K+ +++   ++    +R + T      ++       ++ ++  ++++ E  D   +            L ++     DM    A+L F + V ++++LH+ GIVHRD+K +N+++ S G VKL DFG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>7.7701e-09</Hsp_evalue>
      <Hsp_query-from>642</Hsp_query-from>
      <Hsp_query-to>1082</Hsp_query-to>
      <Hsp_hit-from>38</Hsp_hit-from>
      <Hsp_hit-to>189</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>163</Hsp_align-len>
      <Hsp_qseq>FETIKLISNGAYGAVYLVRHK--ETRQRFAMKKI----NKQNLILRNQIQQAFV-----ERDILTFAENPFVV-----GMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSK</Hsp_qseq>
      <Hsp_hseq>YEIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGHKNIVNLIDLEIVTSSPYDGLYCYQE-------LIDY----DLAKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLAR</Hsp_hseq>
      <Hsp_midline>+E I+ +  GAYG V  V+ K      R A+KKI    NK+ L+ R   +  F+      ++I+   +   V      G++C  E       +++Y    D A ++ +   L     + +  + +  L+Y+H+  ++HRDLKP N+L T  G +K+ DFGL++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YKL198C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:68232:70220:-1 gene:YKL198C transcript:YKL198C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK1 description:Putative serine/threonine protein kinase; regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein; PTK1 has a paralog, PTK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001681]</Hit_def>
  <Hit_accession>YKL198C</Hit_accession>
  <Hit_len>662</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>1.22715e-08</Hsp_evalue>
      <Hsp_query-from>654</Hsp_query-from>
      <Hsp_query-to>1079</Hsp_query-to>
      <Hsp_hit-from>200</Hsp_hit-from>
      <Hsp_hit-to>351</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>157</Hsp_align-len>
      <Hsp_qseq>KLISNGAYGAVYLVRHKETRQR-FAMKKINKQNLILRNQIQQAFVERDILTFA-----------ENPFV-VGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLY--FAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLS</Hsp_qseq>
      <Hsp_hseq>KTIGWGGSCEVRKIRSKYRKKDVFALKKLN----MIYNETPEKFYKRCSKEFIIAKQLSHHVHITNTFLLVKVPTTVYTTRGWGFVME-LGLRDLFAMIQKSGWRSVALAEKFCIFKQVACGVKFCHDQGIAHRDLKPENVLLSPDGVCKLTDFGIS</Hsp_hseq>
      <Hsp_midline>K I  G    V  +R K  ++  FA+KK+N    ++ N+  + F +R    F             N F+ V +  +  T R    VME +   D   +++  G   V +A+ +  F +    +++ H+ GI HRDLKP+N+L++  G  KLTDFG+S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>2.44995e-08</Hsp_evalue>
      <Hsp_query-from>669</Hsp_query-from>
      <Hsp_query-to>1076</Hsp_query-to>
      <Hsp_hit-from>55</Hsp_hit-from>
      <Hsp_hit-to>196</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>143</Hsp_align-len>
      <Hsp_qseq>GAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQ-------AFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGL</Hsp_qseq>
      <Hsp_hseq>GEFGKVKLGWTKASSSNEVPKQVAIK-LIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGF</Hsp_hseq>
      <Hsp_midline>G +G V L   K +      K++  + LI R+ I++        + E + L    +P ++ +    +  +++ +V+E+V GG+    ++    L    A   FA+ +  + Y+H  G+VHRDLK +NLL+    ++ +TDFG </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>2.62382e-08</Hsp_evalue>
      <Hsp_query-from>636</Hsp_query-from>
      <Hsp_query-to>1079</Hsp_query-to>
      <Hsp_hit-from>442</Hsp_hit-from>
      <Hsp_hit-to>601</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>163</Hsp_align-len>
      <Hsp_qseq>EDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENP---------FVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLY-----FAETVLALEYLHNY-GIVHRDLKPDNLLITSMGHVKLTDFGLS</Hsp_qseq>
      <Hsp_hseq>EKFTNVHSIGKGQFSTVYQVTFAQTNKKYAIKAIKPNKY---NSLKRILLEIKILNEVTNQITMDQEGKEYIIDYISSWKFQNSYYIMTELCENGNLDGFLQEQVIAKKKRLEDWRIWKIIVELSLALRFIHDSCHIVHLDLKPANVMITFEGNLKLGDFGMA</Hsp_hseq>
      <Hsp_midline>E F  +  I  G +  VY V   +T +++A+K I        N +++  +E  IL    N          +++    S++ +    ++ E  E G+    L+          + +       E  LAL ++H+   IVH DLKP N++IT  G++KL DFG++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>2.95658e-08</Hsp_evalue>
      <Hsp_query-from>639</Hsp_query-from>
      <Hsp_query-to>1130</Hsp_query-to>
      <Hsp_hit-from>7</Hsp_hit-from>
      <Hsp_hit-to>175</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>174</Hsp_align-len>
      <Hsp_qseq>DFETIKLISNGAYGAVYL---VRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRH-LCMVMEYVEGGDCATLLKNLGALP------VDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKIGLMSLTTNLAALVTL</Hsp_qseq>
      <Hsp_hseq>NYKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESED-EGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLD----LDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTL</Hsp_hseq>
      <Hsp_midline>+++ ++ +  G YG VY    +R  + ++  A+KKI  ++         A  E  +L   ++  +V ++    +  H L +V E+++      L + +  +P       D+ + +  +    + Y H++ I+HRDLKP NLLI   G++KL DFGL++   + L      +VTL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YOR061W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:441534:442553:1 gene:YOR061W transcript:YOR061W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA2 description:Alpha&apos; catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000005587]</Hit_def>
  <Hit_accession>YOR061W</Hit_accession>
  <Hit_len>339</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>4.63853e-08</Hsp_evalue>
      <Hsp_query-from>639</Hsp_query-from>
      <Hsp_query-to>1085</Hsp_query-to>
      <Hsp_hit-from>49</Hsp_hit-from>
      <Hsp_hit-to>192</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>153</Hsp_align-len>
      <Hsp_qseq>DFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILT-FAENPFVVGMFCSFET--KRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLI-TSMGHVKLTDFGLSKI</Hsp_qseq>
      <Hsp_hseq>NYEIINKIGRGKYSEVFSGRCIVNNQKCVIKVLKPV------KMKKIYRELKILTNLTGGPNVVGLYDIVQDADSKIPALIFEEIKNVDFRTLYPTF-KLP-DI-QYYFTQLLIALDYCHSMGIMHRDVKPQNVMIDPTERKLRLIDWGLAEF</Hsp_hseq>
      <Hsp_midline>++E I  I  G Y  V+  R     Q+  +K +         ++++ + E  ILT     P VVG++   +    +   ++ E ++  D  TL      LP D+ Q YF + ++AL+Y H+ GI+HRD+KP N++I  +   ++L D+GL++ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>8.01605e-08</Hsp_evalue>
      <Hsp_query-from>648</Hsp_query-from>
      <Hsp_query-to>1139</Hsp_query-to>
      <Hsp_hit-from>164</Hsp_hit-from>
      <Hsp_hit-to>331</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>TIKLISNGAYGAVYLVRH-KETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSF-ETKRHLCMVMEYVEGGDCATLLKN---LGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITS---MGHVKLTDFGLSKIGLMSLTTNLAALVTLSAT</Hsp_qseq>
      <Hsp_hseq>TNRIVGNGTFGHVLITHNSKERDEDVCYHPENYAVKIIKLKPNKFDKEARILLRLDHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAK----DLNSNKERMHTVVGT</Hsp_hseq>
      <Hsp_midline>T +++ NG +G V +  + KE  +       N    I++ +  +   E  IL   ++P ++ ++ +F +   HL +  + + GGD  + L     L ++    + L   + + AL YLH+  IVHRDLK DN+L+ +      + L DFG++K     L +N   + T+  T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>8.12965e-08</Hsp_evalue>
      <Hsp_query-from>780</Hsp_query-from>
      <Hsp_query-to>1076</Hsp_query-to>
      <Hsp_hit-from>98</Hsp_hit-from>
      <Hsp_hit-to>196</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>99</Hsp_align-len>
      <Hsp_qseq>FVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGL</Hsp_qseq>
      <Hsp_hseq>YREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGF</Hsp_hseq>
      <Hsp_midline>+ E + L    +P +V +    +  R++ +V+EY  GG+    ++    L    A   F++ +  + Y+H+ G+VHRDLK +NLL+    ++ +TDFG </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>8.45312e-08</Hsp_evalue>
      <Hsp_query-from>636</Hsp_query-from>
      <Hsp_query-to>1085</Hsp_query-to>
      <Hsp_hit-from>80</Hsp_hit-from>
      <Hsp_hit-to>228</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>150</Hsp_align-len>
      <Hsp_qseq>EDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKI</Hsp_qseq>
      <Hsp_hseq>KDYHRGHFLGEGGFARCFQIK-DDSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAV</Hsp_hseq>
      <Hsp_midline>+D+     +  G +   + ++  ++ + FA K + K ++      ++   E  I     +P +V     FE   ++ +++E    G    LLK    L     + +  +   A++Y+H+  ++HRDLK  N+   S  ++K+ DFGL+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>1.15069e-07</Hsp_evalue>
      <Hsp_query-from>636</Hsp_query-from>
      <Hsp_query-to>1127</Hsp_query-to>
      <Hsp_hit-from>189</Hsp_hit-from>
      <Hsp_hit-to>369</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>190</Hsp_align-len>
      <Hsp_qseq>EDFETIKLISNGAYGAVYLVRHKETRQRFAMKKI--NKQNLILRNQ-------IQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALP-------VDMAQLYFAETVLA---------LEYLH-NYGIVHRDLKPDNLLITSMGHVKLTDFGLSKIGLMSLTTNLAALVT</Hsp_qseq>
      <Hsp_hseq>QDLVQLGKIGAGNSGTVVKALHVPDSKIVAKKTIPVEQNNSTIINQLVRELSIVKNVKPHENIITF------YGAYYNQHINNEIIILMEY---SDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKLINSIADTFVGTST</Hsp_hseq>
      <Hsp_midline>+D   +  I  G  G V    H    +  A K I   + N  + NQ       ++      +I+TF       G + +      + ++MEY    DC +L K L           V   + +F E  ++         L++L+  Y I+HRD+KP N+LI S G +KL DFG+SK  + S+        T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YJR059W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:545787:548243:1 gene:YJR059W transcript:YJR059W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK2 description:Serine/threonine protein kinase; involved in regulation of ion transport across plasma membrane; carboxyl terminus is essential for glucose-dependent Pma1p activation via phosphorylation of Pma1p-Ser899; enhances spermine uptake; PTK2 has a paralog, PTK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003820]</Hit_def>
  <Hit_accession>YJR059W</Hit_accession>
  <Hit_len>818</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>1.50625e-07</Hsp_evalue>
      <Hsp_query-from>654</Hsp_query-from>
      <Hsp_query-to>1079</Hsp_query-to>
      <Hsp_hit-from>259</Hsp_hit-from>
      <Hsp_hit-to>410</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>158</Hsp_align-len>
      <Hsp_qseq>KLISNGAYGAVYLVRHKETRQR--FAMKKINKQNLILRNQIQQAFVERDILTF------AENPFVVGMF------CSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLY--FAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLS</Hsp_qseq>
      <Hsp_hseq>KPIGSGGSSEVRKVK-SSYRQKDVYALKKLN----MIYHESPEKFYKRCSKEFIIAKHLSHNVHITNTFYLLKVPTTTYTTRGWGFIME-LGVKDLFQLMERTGWKNVPFNEKYCLFKQVAQGIKFCHDNGIAHRDLKPENVLISKEGICKLTDFGIS</Hsp_hseq>
      <Hsp_midline>K I +G    V  V+    RQ+  +A+KK+N    ++ ++  + F +R    F      + N  +   F       +  T R    +ME +   D   L++  G   V   + Y  F +    +++ H+ GI HRDLKP+N+LI+  G  KLTDFG+S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>1.67612e-07</Hsp_evalue>
      <Hsp_query-from>819</Hsp_query-from>
      <Hsp_query-to>1082</Hsp_query-to>
      <Hsp_hit-from>771</Hsp_hit-from>
      <Hsp_hit-to>858</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>90</Hsp_align-len>
      <Hsp_qseq>FVVGMFCSFETKRHLCMVMEYVEGGDCATLL--KNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSK</Hsp_qseq>
      <Hsp_hseq>FVKPM-TAVKKKSTLFIQMEYCENRTLYDLIHSENLNQQRDEYWRL-FRQILEALSYIHSQGIIHRDLKPMNIFIDESRNVKIGDFGLAK</Hsp_hseq>
      <Hsp_midline>FV  M  + + K  L + MEY E      L+  +NL     +  +L F + + AL Y+H+ GI+HRDLKP N+ I    +VK+ DFGL+K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>2.43505e-07</Hsp_evalue>
      <Hsp_query-from>642</Hsp_query-from>
      <Hsp_query-to>1085</Hsp_query-to>
      <Hsp_hit-from>23</Hsp_hit-from>
      <Hsp_hit-to>168</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>150</Hsp_align-len>
      <Hsp_qseq>FETIKLISNGAYGAVYLVRHKETRQRFAMKKINK--QNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKI</Hsp_qseq>
      <Hsp_hseq>YNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLA---KRTYRELKLLKHLRHENLICLQDIFLSPLEDIYFVTELQGTDLHRLLQTR-PLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARI</Hsp_hseq>
      <Hsp_midline>+  +  +  GA+G V       T Q  A+KKI K     +L    ++ + E  +L    +  ++ +   F +       +  ++G D   LL+    L     Q +  + +  L+Y+H+ G++HRDLKP N+LI     +K+ DFGL++I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YKL168C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:131288:133462:-1 gene:YKL168C transcript:YKL168C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KKQ8 description:Putative serine/threonine protein kinase with unknown cellular role; KKQ8 has a paralog, HAL5, that arose from the whole genome duplication [Source:SGD;Acc:S000001651]</Hit_def>
  <Hit_accession>YKL168C</Hit_accession>
  <Hit_len>724</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>3.01007e-07</Hsp_evalue>
      <Hsp_query-from>816</Hsp_query-from>
      <Hsp_query-to>1085</Hsp_query-to>
      <Hsp_hit-from>494</Hsp_hit-from>
      <Hsp_hit-to>587</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>94</Hsp_align-len>
      <Hsp_qseq>PFVVGMFCSFETKRHLCMVMEYVEGGDCATLL----KNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKI</Hsp_qseq>
      <Hsp_hseq>PNILNVFDILEDSSSFIEVMEFCPAGDLYGMLVGKSKLKGRLHPLEADCFMKQLLHGVKFMHDHGIAHCDLKPENILFYPHGLLKICDFGTSSV</Hsp_hseq>
      <Hsp_midline>P ++ +F   E       VME+   GD   +L    K  G L    A  +  + +  ++++H++GI H DLKP+N+L    G +K+ DFG S +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YDL214C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:74446:76545:-1 gene:YDL214C transcript:YDL214C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR2 description:Serine/threonine protein kinase; inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance; PRR2 has a paralog, NPR1, that arose from the whole genome duplication [Source:SGD;Acc:S000002373]</Hit_def>
  <Hit_accession>YDL214C</Hit_accession>
  <Hit_len>699</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>3.28498e-07</Hsp_evalue>
      <Hsp_query-from>657</Hsp_query-from>
      <Hsp_query-to>1112</Hsp_query-to>
      <Hsp_hit-from>366</Hsp_hit-from>
      <Hsp_hit-to>517</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>154</Hsp_align-len>
      <Hsp_qseq>LISNGAYGAVYLVRHKETRQRFAMK--KINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKIGLMSLTTNL</Hsp_qseq>
      <Hsp_hseq>VLGEGSGGKVKLVQRVLDNKVFALKEYRSKKKRESERKYIKNIISEYCIASTLKNPNICETLEILYEKGKIFQILEYCEY-DLFSLVMSEKMHYEEICCL-FKQLINGVKYLHDIGLSHRDLKLDNCVVTRRGILKLIDFGASSVFHYPLSSQM</Hsp_hseq>
      <Hsp_midline>++  G+ G V LV+     + FA+K  +  K+    R  I+    E  I +  +NP +         K  +  ++EY E  D  +L+ +      ++  L F + +  ++YLH+ G+ HRDLK DN ++T  G +KL DFG S +    L++ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>71</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>3.32996e-07</Hsp_evalue>
      <Hsp_query-from>642</Hsp_query-from>
      <Hsp_query-to>1082</Hsp_query-to>
      <Hsp_hit-from>23</Hsp_hit-from>
      <Hsp_hit-to>176</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>154</Hsp_align-len>
      <Hsp_qseq>FETIKLISNGAYGAVYLVRHKETRQ--RFAMKKINK---QNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDC--ATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSK</Hsp_qseq>
      <Hsp_hseq>FQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLAR</Hsp_hseq>
      <Hsp_midline>F+ IK I +GAYG V   R  E  +    A+KK+     + L+ +  +++  + R          +  M   F     +  +  Y E  +C    ++K+   L     Q +  + +  L+Y+H+  ++HRDLKP NLL+ +   +K+ DFGL++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>72</Hit_num>
  <Hit_id>YDL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:424209:425732:1 gene:YDL017W transcript:YDL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC7 description:DDK (Dbf4-dependent kinase) catalytic subunit; required for origin firing and replication fork progression in mitotic S phase through phosphorylation of Mcm2-7p complexes and Cdc45p; kinase activity correlates with cyclical DBF4 expression; required for pre-meiotic DNA replication, meiotic DSB formation, recruitment of monopolin complex to kinetochores during meiosis I, regulation of meiosis-specific Ndt80p; mutation complemented by human CDC7 and DBF4 co-expression [Source:SGD;Acc:S000002175]</Hit_def>
  <Hit_accession>YDL017W</Hit_accession>
  <Hit_len>507</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>3.41383e-07</Hsp_evalue>
      <Hsp_query-from>633</Hsp_query-from>
      <Hsp_query-to>1082</Hsp_query-to>
      <Hsp_hit-from>30</Hsp_hit-from>
      <Hsp_hit-to>187</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>161</Hsp_align-len>
      <Hsp_qseq>EEDFETIKLISNGAYGAVYLVRH--KETRQRFAMKKINK-------QNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKR-HLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLIT-SMGHVKLTDFGLSK</Hsp_qseq>
      <Hsp_hseq>ENEYKLIDKIGEGTFSSVYKAKDITGKITKKFASHFWNYGSNYVALKKIYVTSSPQRIYNELNLLYIMTGSSRVAPLCDAKRVRDQVIAVLPYYPHEEFRTFYRDL---PIKGIKKYIWELLRALKFVHSKGIIHRDIKPTNFLFNLELGRGVLVDFGLAE</Hsp_hseq>
      <Hsp_midline>E +++ I  I  G + +VY  +    +  ++FA    N        + + + +  Q+ + E ++L        V   C  +  R  +  V+ Y    +  T  ++L   P+   + Y  E + AL+++H+ GI+HRD+KP N L    +G   L DFGL++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>73</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>4.55775e-07</Hsp_evalue>
      <Hsp_query-from>693</Hsp_query-from>
      <Hsp_query-to>1082</Hsp_query-to>
      <Hsp_hit-from>243</Hsp_hit-from>
      <Hsp_hit-to>393</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>155</Hsp_align-len>
      <Hsp_qseq>VRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGM---FCSF--ETKRHL--C-MVMEYVEGGDC-ATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLI----------------TSMGHVKLTDFGLSK</Hsp_qseq>
      <Hsp_hseq>LRYKETLSRLE-NSLTRELQVLKSLNHPCIVK---LLGINNPIFVTSKKPLCDLIIKTPRALPPCDMIMSYCPAGDLLAAVMARNGRLEAWLIQRIFTEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLCK</Hsp_hseq>
      <Hsp_midline>+R+KET  R     + ++  +L++      V+   L    NP  V      C    +T R L  C M+M Y   GD  A ++   G L   + Q  F E VLA++YLH   I+HRDLK +N+L+                     ++L DFGL K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>74</Hit_num>
  <Hit_id>YNL183C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:293137:295509:-1 gene:YNL183C transcript:YNL183C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NPR1 description:Protein kinase; stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p; negatively regulates Ldb19p-mediated endocytosis through phosphorylation of Ldb19p, which prevents its association with the plasma membrane; Npr1p activity is negatively regulated via phosphorylation by the TOR complex; NPR1 has a paralog, PRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005127]</Hit_def>
  <Hit_accession>YNL183C</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>5.63833e-07</Hsp_evalue>
      <Hsp_query-from>681</Hsp_query-from>
      <Hsp_query-to>1112</Hsp_query-to>
      <Hsp_hit-from>451</Hsp_hit-from>
      <Hsp_hit-to>594</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>147</Hsp_align-len>
      <Hsp_qseq>AVYLVRHKETRQRFAMKKINK--QNLILRNQIQQAFVERDILTFAENPFVVGMF-CSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKIGLMSLTTNL</Hsp_qseq>
      <Hsp_hseq>SVKLAQRISDNKIFAVKEFRTKFENESKRDYVKKITSEYCIGTTLNHPNIIETIEIVYENDR-ILQVMEYCEYDLFAIVMSN--KMSYEEICCCFKQILTGVQYLHSIGLAHRDLKLDNCVINEKGIVKLIDFGAAVVFSYPFSKNL</Hsp_hseq>
      <Hsp_midline>+V L +     + FA+K+     +N   R+ +++   E  I T   +P ++      +E  R +  VMEY E    A ++ N   +  +     F + +  ++YLH+ G+ HRDLK DN +I   G VKL DFG + +     + NL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>75</Hit_num>
  <Hit_id>YIL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:287790:288908:-1 gene:YIL035C transcript:YIL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA1 description:Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000001297]</Hit_def>
  <Hit_accession>YIL035C</Hit_accession>
  <Hit_len>372</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>7.35688e-07</Hsp_evalue>
      <Hsp_query-from>864</Hsp_query-from>
      <Hsp_query-to>1112</Hsp_query-to>
      <Hsp_hit-from>149</Hsp_hit-from>
      <Hsp_hit-to>229</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>CMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMG-HVKLTDFGLSKIGLMSLTTNL</Hsp_qseq>
      <Hsp_hseq>ALVFEYVDNVDFRILYPKLTDLEI---RFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNV</Hsp_hseq>
      <Hsp_midline> +V EYV+  D   L   L  L +   + Y  E + AL+Y H+ GI+HRD+KP N++I      ++L D+GL++   +++  N+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>76</Hit_num>
  <Hit_id>YDL025C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:405344:407206:-1 gene:YDL025C transcript:YDL025C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RTK1 description:Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002183]</Hit_def>
  <Hit_accession>YDL025C</Hit_accession>
  <Hit_len>620</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>8.35429e-07</Hsp_evalue>
      <Hsp_query-from>660</Hsp_query-from>
      <Hsp_query-to>1073</Hsp_query-to>
      <Hsp_hit-from>308</Hsp_hit-from>
      <Hsp_hit-to>450</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>155</Hsp_align-len>
      <Hsp_qseq>ISNGAYGAVYLVRHKETRQRFAMKKINKQNLILR--NQIQQAFVERDILTFAENPFVVGMFCSFETKRH---------------LCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFG</Hsp_qseq>
      <Hsp_hseq>LGEGASGSVSVVERTDGK-LFACKMFRKPHLNNEGTNQSQLANYSKKVTT---------EFCIGSTLHHENIVETLDMLTEGDTYLLVMEYAPYDFFNLVMSNL--MTQDEVNCYFKQLCHGVNYLHSMGLAHRDLKLDNCVVTKDGILKLIDFG</Hsp_hseq>
      <Hsp_midline>+  GA G+V +V   + +  FA K   K +L     NQ Q A   + + T          FC   T  H                 +VMEY        ++ NL  +  D    YF +    + YLH+ G+ HRDLK DN ++T  G +KL DFG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>77</Hit_num>
  <Hit_id>YMR291W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:852630:854390:1 gene:YMR291W transcript:YMR291W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TDA1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000004905]</Hit_def>
  <Hit_accession>YMR291W</Hit_accession>
  <Hit_len>586</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>9.71447e-07</Hsp_evalue>
      <Hsp_query-from>576</Hsp_query-from>
      <Hsp_query-to>1037</Hsp_query-to>
      <Hsp_hit-from>3</Hsp_hit-from>
      <Hsp_hit-to>188</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>188</Hsp_align-len>
      <Hsp_qseq>TDDATDSRAAESLPKKKPCEE------DFETIKL--------ISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDIL-------------------TFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDM-AQLYFAETVLALEYLHNYGIVHRDLKPDNLLI</Hsp_qseq>
      <Hsp_hseq>TASSSASQLQQRLPEEKPWPQLSGSNADAQTFKCKYVTNHNSLGDGNFSVVKECMNIHTKDLYAMKLIKKQ--TVKNKIQLIQREFDLLRSISEKIRDMEKKNEHSLDIFEGHHHILQLFDYFETADNIVLITQLCQKGDLYEKIVENQCLDLETQVTSYCACLVSVLEFLHSQGIVHRDLKAENVLF</Hsp_hseq>
      <Hsp_midline>T  ++ S+  + LP++KP  +      D +T K         + +G +  V    +  T+  +AMK I KQ   ++N+IQ    E D+L                    F  +  ++ +F  FET  ++ ++ +  + GD    +     L ++     Y A  V  LE+LH+ GIVHRDLK +N+L </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>78</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>1.37891e-06</Hsp_evalue>
      <Hsp_query-from>798</Hsp_query-from>
      <Hsp_query-to>1037</Hsp_query-to>
      <Hsp_hit-from>188</Hsp_hit-from>
      <Hsp_hit-to>267</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>25</Hsp_identity>
      <Hsp_positive>40</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>80</Hsp_align-len>
      <Hsp_qseq>LTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLI</Hsp_qseq>
      <Hsp_hseq>LVSKNNPHCTKFIAFQESANYYYLVTELVTGGEIFDRIVQLTCFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLF</Hsp_hseq>
      <Hsp_midline>L    NP         E+  +  +V E V GG+    +  L     D+A+    +  +A++++H  GIVHRD+KP+NLL </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>79</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>1.76437e-06</Hsp_evalue>
      <Hsp_query-from>627</Hsp_query-from>
      <Hsp_query-to>1082</Hsp_query-to>
      <Hsp_hit-from>34</Hsp_hit-from>
      <Hsp_hit-to>188</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>163</Hsp_align-len>
      <Hsp_qseq>PCEEDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSF-----ETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQL----YFAETVLALEYLHNYG-IVHRDLKPDNLLI-TSMGHVKLTDFGLSK</Hsp_qseq>
      <Hsp_hseq>PVQISFPTTEVVGHGSFGVVFATVIQETNEKVAIKKV-LQDKRFKNR------ELEIMKMLSHINIIDLKYFFYERDSQDEIYLNLILEYMPQS-LYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAK</Hsp_hseq>
      <Hsp_midline>P +  F T +++ +G++G V+    +ET ++ A+KK+  Q+   +N+      E +I+    +  ++ +   F     + + +L +++EY+        L++       M++L    Y  +   +L YLH++  + HRD+KP NLL+      +KL DFG +K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>80</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>2.02367e-06</Hsp_evalue>
      <Hsp_query-from>639</Hsp_query-from>
      <Hsp_query-to>1043</Hsp_query-to>
      <Hsp_hit-from>23</Hsp_hit-from>
      <Hsp_hit-to>182</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>DFETIKLISNGAYGAVYLVR-HKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLK------------------------NLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITS</Hsp_qseq>
      <Hsp_hseq>NYTAEKEIGKGSFATVYRGHLTSDKSQHVAIKEVSRAKLKNKKLLENLEIEIAILKKIKHPHIVGLIDCERTSTDFYLIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLST</Hsp_hseq>
      <Hsp_midline>++   K I  G++  VY      +  Q  A+K++++  L  +  ++   +E  IL   ++P +VG+     T     ++MEY   GD   LLK                        N   L       Y  +   AL++L +  +VHRD+KP NLL+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>81</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>2.2648e-06</Hsp_evalue>
      <Hsp_query-from>660</Hsp_query-from>
      <Hsp_query-to>1082</Hsp_query-to>
      <Hsp_hit-from>41</Hsp_hit-from>
      <Hsp_hit-to>188</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>155</Hsp_align-len>
      <Hsp_qseq>ISNGAYGAV---YLVRHKETR-QRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSF--------ETKRHLCM-VMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLI-TSMGHVKLTDFGLSK</Hsp_qseq>
      <Hsp_hseq>IGRGAFGTVVQAYLTQDKKNWLGPFAIKKVPAHTEYKSRELQ-------ILRIADHPNIVKLQYFFTHLSPQDNKVYQHLAMECLPETLQIEINRYVTNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAK</Hsp_hseq>
      <Hsp_midline>I  GA+G V   YL + K+     FA+KK+         ++Q       IL  A++P +V +   F        +  +HL M  +      +    + N   +P+   +LY  +    + YLH  G+ HRD+KP N+L+    G +K+ DFG +K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>82</Hit_num>
  <Hit_id>YOR267C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:822588:824867:-1 gene:YOR267C transcript:YOR267C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRK1 description:Protein kinase; implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005793]</Hit_def>
  <Hit_accession>YOR267C</Hit_accession>
  <Hit_len>759</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>2.27546e-06</Hsp_evalue>
      <Hsp_query-from>654</Hsp_query-from>
      <Hsp_query-to>1073</Hsp_query-to>
      <Hsp_hit-from>219</Hsp_hit-from>
      <Hsp_hit-to>360</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>145</Hsp_align-len>
      <Hsp_qseq>KLISNGAYGAVYLVRHKETRQRFAMKKIN--KQNLILRNQIQQAFVERDILTFAENPFV---VGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFG</Hsp_qseq>
      <Hsp_hseq>KLLGSGAGGSVKVLVRPTDGATFAVKEFRPRKPNESVKEYAKKCTAEFCIGSTLHHPNVIETVDVFSDSKQNKYY-EVMEYCPIDFFAVVM--TGKMSRGEINCCLKQLTEGVKYLHSMGLAHRDLKLDNCVMTSQGILKLIDFG</Hsp_hseq>
      <Hsp_midline>KL+ +GA G+V ++        FA+K+    K N  ++   ++   E  I +   +P V   V +F   +  ++   VMEY      A ++   G +          +    ++YLH+ G+ HRDLK DN ++TS G +KL DFG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>83</Hit_num>
  <Hit_id>YDL079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:312951:314748:-1 gene:YDL079C transcript:YDL079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRK1 description:Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication [Source:SGD;Acc:S000002237]</Hit_def>
  <Hit_accession>YDL079C</Hit_accession>
  <Hit_len>501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>4.79778e-06</Hsp_evalue>
      <Hsp_query-from>642</Hsp_query-from>
      <Hsp_query-to>1082</Hsp_query-to>
      <Hsp_hit-from>164</Hsp_hit-from>
      <Hsp_hit-to>313</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>158</Hsp_align-len>
      <Hsp_qseq>FETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSF-----ETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQL----YFAETVLALEYLHNYG-IVHRDLKPDNLLI-TSMGHVKLTDFGLSK</Hsp_qseq>
      <Hsp_hseq>YPTTEVVGHGSFGVVVTTVIIETNQKVAIKKV-LQDRRYKNR------ELETMKMLCHPNTVGLQYYFYEKDEEDEVYLNLVLDYMPQS-LYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAK</Hsp_hseq>
      <Hsp_midline>+ T +++ +G++G V      ET Q+ A+KK+  Q+   +N+      E + +    +P  VG+   F     E + +L +V++Y+        L++   L + M ++    Y  +   AL YLHN   I HRD+KP NLL+  +    K+ DFG +K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>84</Hit_num>
  <Hit_id>YDL028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:400997:403291:-1 gene:YDL028C transcript:YDL028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MPS1 description:Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]</Hit_def>
  <Hit_accession>YDL028C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>5.90177e-06</Hsp_evalue>
      <Hsp_query-from>633</Hsp_query-from>
      <Hsp_query-to>1079</Hsp_query-to>
      <Hsp_hit-from>437</Hsp_hit-from>
      <Hsp_hit-to>584</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>163</Hsp_align-len>
      <Hsp_qseq>EEDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGG------------DCATLLKNLGALPVDM--AQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLS</Hsp_qseq>
      <Hsp_hseq>DSQYEKIELLGRGGSSRVYKVKGSGNRV-YALKRVS----------FDAFDDSSIDGFKGE---IELLEKLKDQKRVIQLLDYEMGDGLLYLIMECGDHDLSQILNQRSGMPLDFNFVRFYTKEMLLCIKVVHDAGIVHSDLKPANFVLVK-GILKIIDFGIA</Hsp_hseq>
      <Hsp_midline>+  +E I+L+  G    VY V+    R  +A+K+++            AF +  I  F      + +    + ++ +  +++Y  G             D + +L     +P+D    + Y  E +L ++ +H+ GIVH DLKP N ++   G +K+ DFG++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3255327019</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

