<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0033519-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.87 eAED:0.87 QI:0|0.25|0.22|0.44|0|0|9|151|334</BlastOutput_query-def>
  <BlastOutput_query-len>1156</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0033519-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.87 eAED:0.87 QI:0|0.25|0.22|0.44|0|0|9|151|334</Iteration_query-def>
  <Iteration_query-len>1156</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>680159298</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0045375-RA transcript Note:&quot;Similar to Jade1 Protein Jade-1 (Mus musculus)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.16|0.28|7|1|284</Iteration_query-def>
  <Iteration_query-len>853</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YPR031W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:631515:633761:1 gene:YPR031W transcript:YPR031W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NTO1 description:Subunit of the NuA3 histone acetyltransferase complex; this complex acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3 [Source:SGD;Acc:S000006235]</Hit_def>
  <Hit_accession>YPR031W</Hit_accession>
  <Hit_len>748</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>1.66052e-10</Hsp_evalue>
      <Hsp_query-from>538</Hsp_query-from>
      <Hsp_query-to>708</Hsp_query-to>
      <Hsp_hit-from>294</Hsp_hit-from>
      <Hsp_hit-to>350</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>32</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>60</Hsp_align-len>
      <Hsp_qseq>CYGIACVPAGSWLCRVC---DRGVAAPRCQLCPRRDGAMKPTRGGGKWAHVSCALWIPEV</Hsp_qseq>
      <Hsp_hseq>CYGIIFIPEGKWLCRRCMISKNNFAT--CLMCPSHTGAFKQTDTGS-WVHNICALWLPEL</Hsp_hseq>
      <Hsp_midline>CYGI  +P G WLCR C       A   C +CP   GA K T  G  W H  CALW+PE+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>89</Statistics_hsp-len>
      <Statistics_eff-space>453700065</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061651-RA transcript Note:&quot;Similar to Rgn Regucalcin (Mus musculus)&quot; offset:0 AED:0.32 eAED:0.32 QI:0|0.66|0.71|0.85|0.66|0.42|7|265|310</Iteration_query-def>
  <Iteration_query-len>1198</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>92</Statistics_hsp-len>
      <Statistics_eff-space>708208169</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061652-RA transcript Note:&quot;Similar to FAT4 Protocadherin Fat 4 (Homo sapiens)&quot; offset:0 AED:0.16 eAED:0.17 QI:0|0|0|0.63|1|0.90|11|0|2368</Iteration_query-def>
  <Iteration_query-len>7107</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>106</Statistics_hsp-len>
      <Statistics_eff-space>5011338821</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061654-RA transcript Note:&quot;Similar to Plk4 Serine/threonine-protein kinase PLK4 (Rattus norvegicus)&quot; offset:100 AED:0.37 eAED:0.51 QI:100|0|0|0.62|0.57|0.75|8|0|526</Iteration_query-def>
  <Iteration_query-len>1681</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.5817</Hsp_bit-score>
      <Hsp_score>218</Hsp_score>
      <Hsp_evalue>2.00527e-19</Hsp_evalue>
      <Hsp_query-from>86</Hsp_query-from>
      <Hsp_query-to>646</Hsp_query-to>
      <Hsp_hit-from>68</Hsp_hit-from>
      <Hsp_hit-to>259</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>205</Hsp_align-len>
      <Hsp_qseq>QDFQVMNLLGKGSFACVYRARSCHTGIEVAIKMIDKQAMRRAGMVDRVPCRSGDPTHSSSIPRFWSGVAGP---QMYGCFEDDNYVYLVLEMCHNGEM-SRYPQNQGAPSPRSKRTGXXXXXXXXXXXXXXXXXXXASP--------------DFGLAARLPLPGESRLTVCGTPNYMSPEVASRGPHGTPADAWALGCAAYAML</Hsp_qseq>
      <Hsp_hseq>HDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVE----------HTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQ---TVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEML</Hsp_hseq>
      <Hsp_midline> DFQ+M  LG GSF  V+  RS H G   AIK++ KQ + +   V+          H++   R    V  P   +M+G F+D   +++V++    GE+ S   ++Q  P+P +K   +    +     +     R   P              DFG A  +        T+CGTP+Y++PEV +  P+    D W+LG   Y ML</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.5817</Hsp_bit-score>
      <Hsp_score>218</Hsp_score>
      <Hsp_evalue>2.40225e-19</Hsp_evalue>
      <Hsp_query-from>89</Hsp_query-from>
      <Hsp_query-to>646</Hsp_query-to>
      <Hsp_hit-from>87</Hsp_hit-from>
      <Hsp_hit-to>277</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>204</Hsp_align-len>
      <Hsp_qseq>DFQVMNLLGKGSFACVYRARSCHTGIEVAIKMIDKQAMRRAGMVDRVPCRSGDPTHSSSIPRFWSGVAGP---QMYGCFEDDNYVYLVLEMCHNGEM-SRYPQNQGAPSPRSKRTGXXXXXXXXXXXXXXXXXXXASP--------------DFGLAARLPLPGESRLTVCGTPNYMSPEVASRGPHGTPADAWALGCAAYAML</Hsp_qseq>
      <Hsp_hseq>DFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVE----------HTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVP---DVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEML</Hsp_hseq>
      <Hsp_midline>DFQ++  LG GSF  V+  RS H G   A+K + K  + +   V+          H++   R  S V+ P   +M+G F+D   V++V++    GE+ S   ++Q  P+P +K   +    +     S     R   P              DFG A  +P   +   T+CGTP+Y++PEV S  P+    D W+ G   Y ML</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.0409</Hsp_bit-score>
      <Hsp_score>214</Hsp_score>
      <Hsp_evalue>5.92715e-19</Hsp_evalue>
      <Hsp_query-from>86</Hsp_query-from>
      <Hsp_query-to>646</Hsp_query-to>
      <Hsp_hit-from>85</Hsp_hit-from>
      <Hsp_hit-to>276</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>205</Hsp_align-len>
      <Hsp_qseq>QDFQVMNLLGKGSFACVYRARSCHTGIEVAIKMIDKQAMRRAGMVDRVPCRSGDPTHSSSIPRFWSGVAGP---QMYGCFEDDNYVYLVLEMCHNGEM-SRYPQNQGAPSPRSKRTGXXXXXXXXXXXXXXXXXXXASP--------------DFGLAARLPLPGESRLTVCGTPNYMSPEVASRGPHGTPADAWALGCAAYAML</Hsp_qseq>
      <Hsp_hseq>QDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVE----------HTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVP---DVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEML</Hsp_hseq>
      <Hsp_midline>QDFQ++  LG GSF  V+  RS H G   A+K++ K+ + R   V+          H++      S V  P   +M+G F+D   ++++++    GE+ S   ++Q  P+P +K   +    +     S     R   P              DFG A  +P   +   T+CGTP+Y++PEV S  P+    D W+ G   Y ML</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>3.38373e-13</Hsp_evalue>
      <Hsp_query-from>86</Hsp_query-from>
      <Hsp_query-to>730</Hsp_query-to>
      <Hsp_hit-from>80</Hsp_hit-from>
      <Hsp_hit-to>337</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>63</Hsp_gaps>
      <Hsp_align-len>268</Hsp_align-len>
      <Hsp_qseq>QDFQVMNLLGKGSFACVYRARSCHTGIEVAIKMIDKQAMRRAGMVDRVPCRSGDPTHSSSIPRFWSGVAGPQMYGCFEDDNYVYLVLEMCHNG---EMSRYPQNQGAPSPR--------------SKRTGXXXXXXXXXXXXXXXXXXXASPDFGLAARLPLPGESRLTVCGTPNYMSPEVA--SRGPHGTPADAWALGCAAYAMLP----------------------------------ATILRRLLRRDPGKRPGLPAVLEHPFL</Hsp_qseq>
      <Hsp_hseq>KDYHRGHFLGEGGFARCFQIKD-DSGEIFAAKTVAKASIKSEKT--RKKLLSEIQIHKS-----MSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIG--DFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRDKPISDEGKILIRDILSLDPIERPSLTEIMDYVWF</Hsp_hseq>
      <Hsp_midline>+D+   + LG+G FA  ++ +   +G   A K + K +++      R    S    H S      S     Q   CFEDD+ VY++LE+C NG   E+ +  +    P  R              S+R         +    S    +    DFGLAA L    E + T+CGTPNY++PEV       H    D W+LG   YA+L                                     ++R +L  DP +RP L  ++++ + </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>2.30173e-12</Hsp_evalue>
      <Hsp_query-from>89</Hsp_query-from>
      <Hsp_query-to>787</Hsp_query-to>
      <Hsp_hit-from>823</Hsp_hit-from>
      <Hsp_hit-to>1102</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>57</Hsp_gaps>
      <Hsp_align-len>285</Hsp_align-len>
      <Hsp_qseq>DFQVMNLLGKGSFACVYRARSCHTGIEVAIKMIDKQAMRRAGMVDRVPCRSGDPTHSSSIPR-FWSGVAGPQMYGCFEDDNYVYLVLEMCHNGEMSRYPQNQGAPSPRSK--------------RTGXXXXXXXXXXXXXXXXXXXASPDFGLAARLPLPGESRLTVCGTPNYMSPEVASRGPHGTPADAWALGCAAYAML--------------------------------PATILRRLLRRDPGKRPG-----LPAVLEHPFLADGGGETTAGLMAGPPLRP</Hsp_qseq>
      <Hsp_hseq>NFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTN-----LYCSFQTENRIYFAMEFIGGGDLMWHVQNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFFRNINFDDILNLRVKPPYIP</Hsp_hseq>
      <Hsp_midline>+F ++ +LGKG+F  V  ++S +T    AIK++ K  + +   ++           ++     F +      +Y  F+ +N +Y  +E    G++  + QNQ     R+K                G      +       P       D+GL       G    T CGTP +M+PE+     +    D WA G   Y ML                                   I + LL +DP KR G        V+E PF  +   +    L   PP  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>43.8986</Hsp_bit-score>
      <Hsp_score>102</Hsp_score>
      <Hsp_evalue>7.15177e-11</Hsp_evalue>
      <Hsp_query-from>491</Hsp_query-from>
      <Hsp_query-to>646</Hsp_query-to>
      <Hsp_hit-from>365</Hsp_hit-from>
      <Hsp_hit-to>414</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>19</Hsp_identity>
      <Hsp_positive>27</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>52</Hsp_align-len>
      <Hsp_qseq>DFGLAARLPLPGESRLTVCGTPNYMSPEVASRGPHGTPADAWALGCAAYAML</Hsp_qseq>
      <Hsp_hseq>DFGLSKQIF--SKNTKTPCGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTML</Hsp_hseq>
      <Hsp_midline>DFGL+ ++    ++  T CGT  Y +PEV     +    D W +GC  Y ML</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>35.039</Hsp_bit-score>
      <Hsp_score>79</Hsp_score>
      <Hsp_evalue>7.15177e-11</Hsp_evalue>
      <Hsp_query-from>92</Hsp_query-from>
      <Hsp_query-to>370</Hsp_query-to>
      <Hsp_hit-from>163</Hsp_hit-from>
      <Hsp_hit-to>275</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>113</Hsp_align-len>
      <Hsp_qseq>FQVMNLLGKGSFACVYRA----RSCHTGIE-----VAIKMIDKQAMRRAGMVDRVPCRSGDPTHSSSIPRFWSGVAGPQMY--GCF---------EDDNYVYLVLEMCHNGEM</Hsp_qseq>
      <Hsp_hseq>YKLINKIGEGAFSKVFRAIPAKNSSNEFLTKNYKAVAIKVIKKADLSSINGDHRKKDKGKDSTKTSSRDQVLKEVALHKTVSAGCSQIVAFIDFQETDSYYYIIQELLTGGEI</Hsp_hseq>
      <Hsp_midline>++++N +G+G+F+ V+RA     S +  +      VAIK+I K  +       R   +  D T +SS  +    VA  +    GC          E D+Y Y++ E+   GE+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>23.8682</Hsp_bit-score>
      <Hsp_score>50</Hsp_score>
      <Hsp_evalue>7.15177e-11</Hsp_evalue>
      <Hsp_query-from>421</Hsp_query-from>
      <Hsp_query-to>483</Hsp_query-to>
      <Hsp_hit-from>308</Hsp_hit-from>
      <Hsp_hit-to>328</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>10</Hsp_identity>
      <Hsp_positive>12</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>21</Hsp_align-len>
      <Hsp_qseq>GVIHRDLTLANLLLASDMSTR</Hsp_qseq>
      <Hsp_hseq>GVVHRDIKPENLLFEPIEFTR</Hsp_hseq>
      <Hsp_midline>GV+HRD+   NLL      TR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>6.94163e-10</Hsp_evalue>
      <Hsp_query-from>89</Hsp_query-from>
      <Hsp_query-to>721</Hsp_query-to>
      <Hsp_hit-from>54</Hsp_hit-from>
      <Hsp_hit-to>263</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>226</Hsp_align-len>
      <Hsp_qseq>DFQVMNLLGKGSFACVYRARSCHTGIEVAIKMIDKQAMRRAGMVDRVPCRSGDPTHSSSIPRFWSGVAGPQMYGCFEDDNYVYLVLEMCHNGEMSRYPQNQGAPSPRSKRTGXXXXXXXXXXXXXXXXXXXASP--------------DFGLAARLPLPGESRLTVCGTPNYMSPEVASRGPHGTP-ADAWALGCAAYAMLPATILRRLLRRDPGKRPGLPAVLEH</Hsp_qseq>
      <Hsp_hseq>NYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIE-------REISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLS-NIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVM--------LCRRLPFDDESIPVLFKN</Hsp_hseq>
      <Hsp_midline>++Q++  LG+GSF  V  A    TG +VA+K+I+K+ + ++ M  R+           S  R        ++Y   +  + + +V+E   N       Q        ++R      ++           R   P              DFGL+  +   G    T CG+PNY +PEV S   +  P  D W+ G   Y M        L RR P     +P + ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>7.51574e-10</Hsp_evalue>
      <Hsp_query-from>491</Hsp_query-from>
      <Hsp_query-to>730</Hsp_query-to>
      <Hsp_hit-from>175</Hsp_hit-from>
      <Hsp_hit-to>287</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>114</Hsp_align-len>
      <Hsp_qseq>DFGLAARLPLPGESRLTVCGTPNYMSPEVASRGPH-GTPADAWALGCAAYAMLPA---------------------------------TILRRLLRRDPGKRPGLPAVLEHPFL</Hsp_qseq>
      <Hsp_hseq>DFGFT-RECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDAKVIPDDARDLISRLLAKNPGERPSLSQVLRHPFL</Hsp_hseq>
      <Hsp_midline>DFG   R  +   +  TVCGT  YM+PE+  R  + G   D W+LG   Y ++                                    ++ RLL ++PG+RP L  VL HPFL</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>23.8682</Hsp_bit-score>
      <Hsp_score>50</Hsp_score>
      <Hsp_evalue>7.51574e-10</Hsp_evalue>
      <Hsp_query-from>415</Hsp_query-from>
      <Hsp_query-to>462</Hsp_query-to>
      <Hsp_hit-from>148</Hsp_hit-from>
      <Hsp_hit-to>165</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>10</Hsp_identity>
      <Hsp_positive>13</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>18</Hsp_align-len>
      <Hsp_qseq>AHGV--IHRDLTLANLLL</Hsp_qseq>
      <Hsp_hseq>AHSMHCVHRDLKLENILL</Hsp_hseq>
      <Hsp_midline>AH +  +HRDL L N+LL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>1.20768e-09</Hsp_evalue>
      <Hsp_query-from>89</Hsp_query-from>
      <Hsp_query-to>646</Hsp_query-to>
      <Hsp_hit-from>103</Hsp_hit-from>
      <Hsp_hit-to>295</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>201</Hsp_align-len>
      <Hsp_qseq>DFQVMNLLGKGSFACVYRARSCHTGIEVAIKMIDKQAMRRAGMVDRVPCRSGDPTHSSSIPRFWSGVAGPQMYGCFEDDNYVYLVLEMCHNGEMSRY-----PQNQGAPSPRSKRTGXXXXXXXXXXXXXX----------XXXXXASPDFGLAARLPLPGESRLTVCGTPNYMSPEVASRGPHGTPADAWALGCAAYAML</Hsp_qseq>
      <Hsp_hseq>DFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFR-REVEIQTSLNHPNL------TKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINP-PENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELL</Hsp_hseq>
      <Hsp_midline>DF++   LGKG F  VY  R   TG   A+K+++K+ + +  +  +   R  +   S + P         + YG F D+  VYL++E   NGEM +      P N    S    +  ++                              DFG +   P P   R TVCGT +Y+SPE+     +    DAWALG  A+ +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YMR291W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:852630:854390:1 gene:YMR291W transcript:YMR291W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TDA1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000004905]</Hit_def>
  <Hit_accession>YMR291W</Hit_accession>
  <Hit_len>586</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>39.6614</Hsp_bit-score>
      <Hsp_score>91</Hsp_score>
      <Hsp_evalue>1.27333e-09</Hsp_evalue>
      <Hsp_query-from>104</Hsp_query-from>
      <Hsp_query-to>391</Hsp_query-to>
      <Hsp_hit-from>43</Hsp_hit-from>
      <Hsp_hit-to>149</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>25</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>107</Hsp_align-len>
      <Hsp_qseq>NLLGKGSFACVYRARSCHTGIEVAIKMIDKQAMR-RAGMVDR---------VPCRSGDPTHSSSIPRFWSGVAGPQMYGCFEDDNYVYLVLEMCHNGEM-SRYPQNQ</Hsp_qseq>
      <Hsp_hseq>NSLGDGNFSVVKECMNIHTKDLYAMKLIKKQTVKNKIQLIQREFDLLRSISEKIRDMEKKNEHSLDIFEGHHHILQLFDYFETADNIVLITQLCQKGDLYEKIVENQ</Hsp_hseq>
      <Hsp_midline>N LG G+F+ V    + HT    A+K+I KQ ++ +  ++ R            R  +  +  S+  F       Q++  FE  + + L+ ++C  G++  +  +NQ</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>35.8094</Hsp_bit-score>
      <Hsp_score>81</Hsp_score>
      <Hsp_evalue>1.27333e-09</Hsp_evalue>
      <Hsp_query-from>491</Hsp_query-from>
      <Hsp_query-to>643</Hsp_query-to>
      <Hsp_hit-from>220</Hsp_hit-from>
      <Hsp_hit-to>285</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>27</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>66</Hsp_align-len>
      <Hsp_qseq>DFGLAARLPLPGESRLT-VCGTPNYMSPEVAS--------------RGPHGTPADAWALGCAAYAM</Hsp_qseq>
      <Hsp_hseq>DFGLAAEYNTSKVNSLKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGCPVDIWALGVLTYFM</Hsp_hseq>
      <Hsp_midline>DFGLAA       + L    GT +Y++PE+                   +G P D WALG   Y M</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>23.0978</Hsp_bit-score>
      <Hsp_score>48</Hsp_score>
      <Hsp_evalue>1.27333e-09</Hsp_evalue>
      <Hsp_query-from>415</Hsp_query-from>
      <Hsp_query-to>462</Hsp_query-to>
      <Hsp_hit-from>173</Hsp_hit-from>
      <Hsp_hit-to>188</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>7</Hsp_identity>
      <Hsp_positive>11</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>16</Hsp_align-len>
      <Hsp_qseq>AHGVIHRDLTLANLLL</Hsp_qseq>
      <Hsp_hseq>SQGIVHRDLKAENVLF</Hsp_hseq>
      <Hsp_midline>+ G++HRDL   N+L </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>7.46572e-09</Hsp_evalue>
      <Hsp_query-from>110</Hsp_query-from>
      <Hsp_query-to>646</Hsp_query-to>
      <Hsp_hit-from>43</Hsp_hit-from>
      <Hsp_hit-to>233</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>204</Hsp_align-len>
      <Hsp_qseq>LGKGSFACVYRARSCHTGIEVAIKMIDKQAMR-----RAGMVDRVPCRSGDPTHSSSIPRF--WSGVAGPQMYGCFEDDNYVYLVLEMCHNGEM-SRYPQNQGAPSPRSKRTGXXXXXXXXXXXXXXXXXXXASP-----------------DFGLAARLPLPGESRLTVCGTPNYMSPEVASRGPHGTPADAWALGCAAYAML</Hsp_qseq>
      <Hsp_hseq>LGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQ--RLHHPNIVAFKDW-----------FESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLL</Hsp_hseq>
      <Hsp_midline>LG G+F  V +A++  TG +VA+K++ K+A++        + D +        H  +I  F  W           FE  +  Y++ ++   GE+  R  +        + R      ++     S     R   P                 DFG+A RL    E      G+  Y++PEV ++  HG P D W++G   Y +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>1.64085e-08</Hsp_evalue>
      <Hsp_query-from>86</Hsp_query-from>
      <Hsp_query-to>778</Hsp_query-to>
      <Hsp_hit-from>123</Hsp_hit-from>
      <Hsp_hit-to>407</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>70</Hsp_gaps>
      <Hsp_align-len>293</Hsp_align-len>
      <Hsp_qseq>QDFQVMNLLGKGSFACVYRARSCHTGIEVAIKMIDKQAMRRAGMVDRVPCRSGDPTHSSSIPRFWSGVAGP-QMYGCFEDDNYVYLVLEMCHNGEM--------------SRYPQNQGAPSPRS-KRTGXXXXXXXXXXXXXXXXXXXASPDFGLAARLP--------------LPGESRLTVCGTPNYMSPEVASRGPHGTPADAWALGCAAYAMLP--------------------------------ATILRRLLRRDPGKRPGLPAVLEHPFLADGGGETTAGLMAGPP</Hsp_qseq>
      <Hsp_hseq>KDFKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYV-------TVEKLALQKLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSK-SFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKIQYAFTAGFPQIVKDLVKKLLVRDPNDRLTIKQIKAHLFFHEVNFEDGSVWDDNPP</Hsp_hseq>
      <Hsp_midline>+DF+    LG GS++ V  A +  +G + A+K++ K+ + R   V  V       T      +  +G  G  +++  F+D+  +Y +LE   +G+               +RY  +Q   +  S    G      +          +    DFG A  LP              L  +S+ +  GT  Y+SPE+ +     +  D WA GC  Y ML                                   ++++LL RDP  R  +  +  H F  +   E  +     PP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>2.12233e-08</Hsp_evalue>
      <Hsp_query-from>86</Hsp_query-from>
      <Hsp_query-to>646</Hsp_query-to>
      <Hsp_hit-from>195</Hsp_hit-from>
      <Hsp_hit-to>402</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>218</Hsp_align-len>
      <Hsp_qseq>QDFQVMN-LLGKGSFACVYRARSCHTGIEVAIKMIDKQAMRRAGMVDRVPCRSGDPTHSSSIPRFWSGVAGPQMYGCFEDDNYVYLVLEMCHNGEMSRYPQNQGAPSPRSKRTGXXXXXXXXXXXXXXXXX-----------------XXASPDFGLAARLPLPGESRLTVCGTPNYMSPEVA-------------SRGPHGTPADAWALGCAAYAML</Hsp_qseq>
      <Hsp_hseq>KDFSIIDEVVGQGAFATVKKAIERTTGKTFAVKIISKRKV--IGNMDGV-TRELEVLQKLNHPRI------VRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGL-AKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVIL</Hsp_hseq>
      <Hsp_midline>+DF +++ ++G+G+FA V +A    TG   A+K+I K+ +   G +D V  R  +     + PR        ++ G +ED    Y+V+E    G++  +    GA    + R  S    +      S                          DFGL A++   G    T CGT  Y++PEV               R  + +  D W++GC  Y +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>9.64385e-08</Hsp_evalue>
      <Hsp_query-from>491</Hsp_query-from>
      <Hsp_query-to>646</Hsp_query-to>
      <Hsp_hit-from>757</Hsp_hit-from>
      <Hsp_hit-to>808</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>29</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>52</Hsp_align-len>
      <Hsp_qseq>DFGLAARLPLPGESRLTVCGTPNYMSPEVASRGPHGTPADAWALGCAAYAML</Hsp_qseq>
      <Hsp_hseq>DFGFCAQINELNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMI</Hsp_hseq>
      <Hsp_midline>DFG  A++      R T+ GTP +M+PEV SR  +G   D W+LG     M+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>23.8682</Hsp_bit-score>
      <Hsp_score>50</Hsp_score>
      <Hsp_evalue>9.64385e-08</Hsp_evalue>
      <Hsp_query-from>415</Hsp_query-from>
      <Hsp_query-to>465</Hsp_query-to>
      <Hsp_hit-from>732</Hsp_hit-from>
      <Hsp_hit-to>748</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>8</Hsp_identity>
      <Hsp_positive>13</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>17</Hsp_align-len>
      <Hsp_qseq>AHGVIHRDLTLANLLLA</Hsp_qseq>
      <Hsp_hseq>SKGVLHRDIKSDNILLS</Hsp_hseq>
      <Hsp_midline>+ GV+HRD+   N+LL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YAR018C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:170396:171703:-1 gene:YAR018C transcript:YAR018C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN3 description:Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol [Source:SGD;Acc:S000000071]</Hit_def>
  <Hit_accession>YAR018C</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>9.80131e-08</Hsp_evalue>
      <Hsp_query-from>491</Hsp_query-from>
      <Hsp_query-to>643</Hsp_query-to>
      <Hsp_hit-from>231</Hsp_hit-from>
      <Hsp_hit-to>281</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>28</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>51</Hsp_align-len>
      <Hsp_qseq>DFGLAARLPLPGESRLTVCGTPNYMSPEVASRGPHGTPADAWALGCAAYAM</Hsp_qseq>
      <Hsp_hseq>DFGLAKSLETSIQFATTYVGTPYYMSPEVLMDQPYSPLSDIWSLGCVIFEM</Hsp_hseq>
      <Hsp_midline>DFGLA  L    +   T  GTP YMSPEV    P+   +D W+LGC  + M</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>1.04239e-07</Hsp_evalue>
      <Hsp_query-from>110</Hsp_query-from>
      <Hsp_query-to>730</Hsp_query-to>
      <Hsp_hit-from>25</Hsp_hit-from>
      <Hsp_hit-to>289</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>60</Hsp_gaps>
      <Hsp_align-len>266</Hsp_align-len>
      <Hsp_qseq>LGKGSFACVYRARSCHTGIEVAIKMIDKQAMRRAGMVDRVPCRSGDP-------THSSSIPRFWSGVAGPQMYGCFEDDNYVYLVLEMCHNGEMSRYPQNQG-APSPRSKR--------------TGXXXXXXXXXXXXXXXXXXXASPDFGLAARLPLPGESRLTVCGTPNYMSPEVASRGPH-GTPADAWALGCAAYAMLP------------------------------------ATILRRLLRRDPGKRPGLPAVLEHPFL</Hsp_qseq>
      <Hsp_hseq>LGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAA-LETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERRIKTRDILKHPLL</Hsp_hseq>
      <Hsp_midline>LG GS   V  AR+  TG E A+K+I K       +       S  P            I +  +     ++Y  +E +  +YLVLE    GE+      +G  P   + R               G      +               DFG+AA L   G+   T CG+P+Y +PE+ S  P+ G  +D W+ G   +A+L                                       ++R++L  DP +R     +L+HP L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>3.48016e-07</Hsp_evalue>
      <Hsp_query-from>491</Hsp_query-from>
      <Hsp_query-to>646</Hsp_query-to>
      <Hsp_hit-from>258</Hsp_hit-from>
      <Hsp_hit-to>309</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>25</Hsp_identity>
      <Hsp_positive>34</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>53</Hsp_align-len>
      <Hsp_qseq>DFGLAARLPLPGESRLTVCGTPNYMSPEVASRGP-HGTPADAWALGCAAYAML</Hsp_qseq>
      <Hsp_hseq>DFGMAA-LELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALL</Hsp_hseq>
      <Hsp_midline>DFG+AA L LP +   T CG+P+Y SPE+    P HG P+D W+ G   +A+L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>5.29269e-07</Hsp_evalue>
      <Hsp_query-from>110</Hsp_query-from>
      <Hsp_query-to>646</Hsp_query-to>
      <Hsp_hit-from>27</Hsp_hit-from>
      <Hsp_hit-to>221</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>203</Hsp_align-len>
      <Hsp_qseq>LGKGSFACVYRARSCHTGIEVAIKMIDKQAMRRAGMVDRVPCRSGDPT-------HSSSIPRFWSGVAGPQMYGCFEDDNYVYLVLEMCHNGEMSRYPQNQGAPSPRSKRT----------------GXXXXXXXXXXXXXXXXXXXASPDFGLAARLPLPGESRLTVCGTPNYMSPEVASRGPH-GTPADAWALGCAAYAML</Hsp_qseq>
      <Hsp_hseq>LGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNG------NHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHG-PLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAA-LQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALL</Hsp_hseq>
      <Hsp_midline>LG GS   V  A+   TG   A+K+I K      G        S D +           I +  S      +Y  +E +N +YL+LE    GE+     + G P P  +                  G      +               DFG+AA L    +   T CG+P+Y +PE+ S  P+ G  +D W+ G   +A+L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>5.3068e-07</Hsp_evalue>
      <Hsp_query-from>83</Hsp_query-from>
      <Hsp_query-to>646</Hsp_query-to>
      <Hsp_hit-from>22</Hsp_hit-from>
      <Hsp_hit-to>212</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>204</Hsp_align-len>
      <Hsp_qseq>SQDFQVMNLLGKGSFACVYRARSCHTGIEVAIKMIDKQAMRRAGMVDRVPCRSGDPTHSSSIPRFWSGVAGPQMYGCFEDDNYVYLVLEMCHNGEMSRYPQ--NQGAPSPRSKR--------------TGXXXXXXXXXXXXXXXXXXXASPDFGLAARLPLPGESRLTVCGTPNYMSPEVASRGPHGTPADAWALGCAAYAML</Hsp_qseq>
      <Hsp_hseq>SVQYHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNHNNIV----------KYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVST---IVNSSALTLAGTLNWMAPEILGNRGASTLSDIWSLGATVVEML</Hsp_hseq>
      <Hsp_midline>S  + +  ++G+GS+  VY+A + HT   VAIK +  +       +        +  H++ +          + +G       +Y++LE C NG + R     + G     SK                G      ++              DFG++    +   S LT+ GT N+M+PE+       T +D W+LG     ML</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>41.9726</Hsp_bit-score>
      <Hsp_score>97</Hsp_score>
      <Hsp_evalue>8.91482e-07</Hsp_evalue>
      <Hsp_query-from>491</Hsp_query-from>
      <Hsp_query-to>730</Hsp_query-to>
      <Hsp_hit-from>193</Hsp_hit-from>
      <Hsp_hit-to>313</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>43</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>121</Hsp_align-len>
      <Hsp_qseq>DFGLAARLPLPGESRLTVCGTPNYMSPE-VASRGPH-GTPADAWALGCAAYAML---------------------------------------PATILRRLLRRDPGKRPGLPAVLEHPFL</Hsp_qseq>
      <Hsp_hseq>DFGFVNEFCSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGRLYNYINSTPLKFPDYILPIPRDLLRRMLVSDPKKRINLKQIKKHEWL</Hsp_hseq>
      <Hsp_midline>DFG         E   T CG+P Y +PE V S  P+    AD W+ G   YA+L                                       P  +LRR+L  DP KR  L  + +H +L</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>27.7202</Hsp_bit-score>
      <Hsp_score>60</Hsp_score>
      <Hsp_evalue>8.91482e-07</Hsp_evalue>
      <Hsp_query-from>415</Hsp_query-from>
      <Hsp_query-to>462</Hsp_query-to>
      <Hsp_hit-from>168</Hsp_hit-from>
      <Hsp_hit-to>183</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>10</Hsp_identity>
      <Hsp_positive>13</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>16</Hsp_align-len>
      <Hsp_qseq>AHGVIHRDLTLANLLL</Hsp_qseq>
      <Hsp_hseq>SKGLVHRDLKLENLLL</Hsp_hseq>
      <Hsp_midline>+ G++HRDL L NLLL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>44.669</Hsp_bit-score>
      <Hsp_score>104</Hsp_score>
      <Hsp_evalue>1.03722e-06</Hsp_evalue>
      <Hsp_query-from>491</Hsp_query-from>
      <Hsp_query-to>643</Hsp_query-to>
      <Hsp_hit-from>162</Hsp_hit-from>
      <Hsp_hit-to>213</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>30</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>52</Hsp_align-len>
      <Hsp_qseq>DFGLAARLPLPGESRLTVCGTPNYMSPEVASRGP-HGTPADAWALGCAAYAM</Hsp_qseq>
      <Hsp_hseq>DFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEI</Hsp_hseq>
      <Hsp_midline>DFG+AA++      R T+ GTP +M+PEV   G  + T  D W+LG   Y +</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>24.6386</Hsp_bit-score>
      <Hsp_score>52</Hsp_score>
      <Hsp_evalue>1.03722e-06</Hsp_evalue>
      <Hsp_query-from>421</Hsp_query-from>
      <Hsp_query-to>486</Hsp_query-to>
      <Hsp_hit-from>139</Hsp_hit-from>
      <Hsp_hit-to>160</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>8</Hsp_identity>
      <Hsp_positive>16</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>22</Hsp_align-len>
      <Hsp_qseq>GVIHRDLTLANLLLASDMSTRI</Hsp_qseq>
      <Hsp_hseq>NVIHRDIKAANVLITNEGNVKL</Hsp_hseq>
      <Hsp_midline> VIHRD+  AN+L+ ++ + ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>1.53193e-06</Hsp_evalue>
      <Hsp_query-from>86</Hsp_query-from>
      <Hsp_query-to>715</Hsp_query-to>
      <Hsp_hit-from>177</Hsp_hit-from>
      <Hsp_hit-to>416</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>247</Hsp_align-len>
      <Hsp_qseq>QDFQVMNLLGKGSFACVYRARSCHTGIEVAIKMIDKQAMRRAGMVDRVPCRSGDPTHSSSIPRFWSGVAGPQMYGCFEDDNYVYLVLEMCHNGEMSRYPQNQGAPSPRSKR---------------TGXXXXXXXXXXXXXXXXXXXASPDFGLAARL------------PLPGESRLTVCGTPNYMSPEVASRGPHGTPADAWALGCAAYAML------PAT----ILRRLLRRDPGKRPGLPAVL</Hsp_qseq>
      <Hsp_hseq>KDFKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSI------EKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSK-SFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKVQYAFTPGFPLII</Hsp_hseq>
      <Hsp_midline>+DF+  +++G G+++ V  A S  T    A K+++K+ + R   V  V          +++ +  +  +  +++  F+D++ +Y +LE   NG+     +  G+      R                G      +          +    DFG A  L             L   S+ +  GT  Y+SPE+ +        D WA GC  + M+       AT      +++++      PG P ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.9802</Hsp_bit-score>
      <Hsp_score>110</Hsp_score>
      <Hsp_evalue>6.05222e-06</Hsp_evalue>
      <Hsp_query-from>86</Hsp_query-from>
      <Hsp_query-to>730</Hsp_query-to>
      <Hsp_hit-from>119</Hsp_hit-from>
      <Hsp_hit-to>414</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>95</Hsp_gaps>
      <Hsp_align-len>303</Hsp_align-len>
      <Hsp_qseq>QDFQVMNLLGKGSFACVYRARSCHTGIE--VAIKMIDKQAMRRAGMVDRVPCRSGDPTHSSSIPRFWSGVAGPQM----------YGCFEDD-NYVYLVLEM--------------CHNGEMSRYPQNQGA------------------------PSPRSKRTGXXXXXXXXXXXXXXXXXXXAS-PDFGLAARLPLPGESRLTVCGTPNYMSPEVASRGPHGTPADAWALGCAAYAML----------PATILRR--------------------------LLRRDPGKRPGLPAVLEHPFL</Hsp_qseq>
      <Hsp_hseq>HNYKLLNKIGEGAFSRVFKAVGINTDDQAPVAIKAIIKKGISSDAIL-----KGNDRIQGSSRKKVLNEVAIHKLVSKNNPHCTKFIAFQESANYYYLVTELVTGGEIFDRIVQLTCFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLR--NNTAKTPCGTIEYVASEVFTSKRYSMKVDMWSIGCVLFTLLCGYPPFYEKNEKTLLKKISRGDYEFLAPWWDNISSGAKNAVTHLLEVDPNKRYDIDDFLNDPWL</Hsp_hseq>
      <Hsp_midline> +++++N +G+G+F+ V++A   +T  +  VAIK I K+ +    ++     +  D    SS  +  + VA  ++          +  F++  NY YLV E+              C + +++R+   Q A                        P P     G                       DFGLA +L     +  T CGT  Y++ EV +   +    D W++GC  + +L            T+L++                          LL  DP KR  +   L  P+L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1063486155</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061655-RA transcript Note:&quot;Similar to FAXDC2 Fatty acid hydroxylase domain-containing protein 2 (Macaca fascicularis)&quot; offset:276 AED:0.01 eAED:0.01 QI:276|1|1|1|0.12|0.22|9|3778|336</Iteration_query-def>
  <Iteration_query-len>5065</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YGR060W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:610564:611493:1 gene:YGR060W transcript:YGR060W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ERG25 description:C-4 methyl sterol oxidase; catalyzes the first of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants accumulate the sterol intermediate 4,4-dimethylzymosterol; human MSMO1 functionally complements the growth defect caused by repression of ERG25 expression [Source:SGD;Acc:S000003292]</Hit_def>
  <Hit_accession>YGR060W</Hit_accession>
  <Hit_len>309</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.5666</Hsp_bit-score>
      <Hsp_score>192</Hsp_score>
      <Hsp_evalue>6.87563e-16</Hsp_evalue>
      <Hsp_query-from>451</Hsp_query-from>
      <Hsp_query-to>1143</Hsp_query-to>
      <Hsp_hit-from>34</Hsp_hit-from>
      <Hsp_hit-to>270</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>249</Hsp_align-len>
      <Hsp_qseq>DFWQSQWALFYNAYEEEPFKIFVFCSMVVPTG-MFWLFNALLMCVDVTGW-----PAFFLRYKIQADKNVPVDPAKLRNAIFTVLANQLFISFPMVLIAYVISLWRGGTCGPELPTFHWVLLELLVFGLIEEVMFYYSHRLFHHPALYKRFHKQHHEWTAPIGLVSLYAHPLEHF---LSNMLPPVMGPVLMGS-HAATIMLWFTMALLSTSVAHCGYHLP-----LLP---SPEFHDFHHLKFNQCYG</Hsp_qseq>
      <Hsp_hseq>NFMEKYWAAWYSYMNND----------VLATGLMFFLLHEFMYFFRCLPWFIIDQIPYFRRWKLQPTK-IPSAKEQLY-CLKSVLLSHFLVEAIPIWTFHPMCEKLGITVEVPFPSLKTMALEIGLFFVLEDTWHYWAHRLFHYGVFYKYIHKQHHRYAAPFGLSAEYAHPAETLSLGFGTVGMPILYVMYTGKLHLFTLCVWITLRLFQAVDSHSGYDFPWSLNKIMPFWAGAEHHDLHHHYFIGNYA</Hsp_hseq>
      <Hsp_midline>+F +  WA +Y+    +          V+ TG MF+L +  +       W       +F R+K+Q  K +P    +L   + +VL +   +    +   + +    G T     P+   + LE+ +F ++E+   Y++HRLFH+   YK  HKQHH + AP GL + YAHP E        +  P++  +  G  H  T+ +W T+ L     +H GY  P     ++P     E HD HH  F   Y </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YDR297W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1056551:1057600:1 gene:YDR297W transcript:YDR297W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SUR2 description:Sphinganine C4-hydroxylase; catalyses the conversion of sphinganine to phytosphingosine in sphingolipid biosyntheis [Source:SGD;Acc:S000002705]</Hit_def>
  <Hit_accession>YDR297W</Hit_accession>
  <Hit_len>349</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>4.50957e-10</Hsp_evalue>
      <Hsp_query-from>838</Hsp_query-from>
      <Hsp_query-to>1128</Hsp_query-to>
      <Hsp_hit-from>173</Hsp_hit-from>
      <Hsp_hit-to>277</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>106</Hsp_align-len>
      <Hsp_qseq>YYSHRLFH-HPALYKRFHKQHHEWTAPIGLVSLYAHPLEHFLSNMLPPVMGPVLMG-SHAATIMLWFTMALLSTSVAHCGYHLPLLP-------SPEFHDFHHLKF</Hsp_qseq>
      <Hsp_hseq>YFLHRLMHMNKTLYKWFHSVHHELYVPYAYGALFNNPVEGFLLDTLGTGIAMTLTHLTHREQIIL-FTFATMKTVDDHCGYALPLDPFQWLFPNNAVYHDIHHQQF</Hsp_hseq>
      <Hsp_midline>Y+ HRL H +  LYK FH  HHE   P    +L+ +P+E FL + L   +   L   +H   I+L FT A + T   HCGY LPL P       +  +HD HH +F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YLR056W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:253861:254958:1 gene:YLR056W transcript:YLR056W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ERG3 description:C-5 sterol desaturase; glycoprotein that catalyzes the introduction of a C-5(6) double bond into episterol, a precursor in ergosterol biosynthesis; transcriptionally down-regulated when ergosterol is in excess; mutants are viable, but cannot grow on non-fermentable carbon sources; substrate of HRD ubiquitin ligase; mutation is functionally complemented by human SC5D [Source:SGD;Acc:S000004046]</Hit_def>
  <Hit_accession>YLR056W</Hit_accession>
  <Hit_len>365</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>8.84969e-10</Hsp_evalue>
      <Hsp_query-from>790</Hsp_query-from>
      <Hsp_query-to>1194</Hsp_query-to>
      <Hsp_hit-from>181</Hsp_hit-from>
      <Hsp_hit-to>315</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>139</Hsp_align-len>
      <Hsp_qseq>VLLELLVFGLIEEVMFYYSHRLFHHPALYKRFHKQHHEWTAPIGLVSLYAHPLEHFLSNMLPPVMGPVLMGSHAATIMLWFTMALLSTSVAHCGYHL---PLLPSPEFHDFHHLKFNQCYGVLGVL-DRLHGTDAAFRR</Hsp_qseq>
      <Hsp_hseq>LIIEYFTFIFFTDCGVYLAHRWLHWPRVYRALHKPHHKWLVCTPFASHSFHPVDGFLQSISYHIY-PLILPLHKVSYLILFTFVNFWTVMIHDGQYLSNNPAVNGTACHTVHHLYFNYNYGQFTTLWDRLGG---SYRR</Hsp_hseq>
      <Hsp_midline>+++E   F    +   Y +HR  H P +Y+  HK HH+W       S   HP++ FL ++   +  P+++  H  + ++ FT     T + H G +L   P +     H  HHL FN  YG    L DRL G   ++RR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3541313195</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061658-RA transcript Note:&quot;Similar to Pkd1l2 Polycystic kidney disease protein 1-like 2 (Mus musculus)&quot; offset:0 AED:0.44 eAED:0.52 QI:0|0.31|0.35|0.47|0.93|0.94|17|0|1554</Iteration_query-def>
  <Iteration_query-len>4665</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3244155684</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0045827-RA transcript Note:&quot;Similar to PKD1L2 Polycystic kidney disease protein 1-like 2 (Homo sapiens)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.5|0.2|5|0|272</Iteration_query-def>
  <Iteration_query-len>819</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>88</Statistics_hsp-len>
      <Statistics_eff-space>431654395</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061659-RA transcript Note:&quot;Similar to Taar7b Trace amine-associated receptor 7b (Rattus norvegicus)&quot; offset:0 AED:0.32 eAED:0.32 QI:0|-1|0|1|-1|1|1|0|316</Iteration_query-def>
  <Iteration_query-len>951</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>526655209</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061660-RA transcript Note:&quot;Similar to PFAS Phosphoribosylformylglycinamidine synthase (Homo sapiens)&quot; offset:86 AED:0.46 eAED:0.46 QI:86|1|0.66|1|0.5|0.66|3|0|134</Iteration_query-def>
  <Iteration_query-len>491</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>82</Statistics_hsp-len>
      <Statistics_eff-space>192202227</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0045828-RA transcript Note:&quot;Similar to PFAS Phosphoribosylformylglycinamidine synthase (Homo sapiens)&quot; offset:1857 AED:0.19 eAED:0.19 QI:1857|0.36|0.42|0.92|0.36|0.38|26|1027|481</Iteration_query-def>
  <Iteration_query-len>4330</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YGR061C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:611889:615965:-1 gene:YGR061C transcript:YGR061C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ADE6 description:Formylglycinamidine-ribonucleotide (FGAM)-synthetase; catalyzes a step in the &apos;de novo&apos; purine nucleotide biosynthetic pathway [Source:SGD;Acc:S000003293]</Hit_def>
  <Hit_accession>YGR061C</Hit_accession>
  <Hit_len>1358</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>132.88</Hsp_bit-score>
      <Hsp_score>333</Hsp_score>
      <Hsp_evalue>1.47898e-31</Hsp_evalue>
      <Hsp_query-from>2626</Hsp_query-from>
      <Hsp_query-to>3270</Hsp_query-to>
      <Hsp_hit-from>1102</Hsp_hit-from>
      <Hsp_hit-to>1356</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>94</Hsp_identity>
      <Hsp_positive>124</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>258</Hsp_align-len>
      <Hsp_qseq>NGDREMAAALHMAGF-----------------ERFRGLVFVGGFSYADVLGSARGWAASVLFNX-XXXXXXXXXXXXXDTFSLG-----------EALAPGVVLAP----NVSGRFESRFVSVRVQEDSPAXXXXXXXXXXXX-----XWVAHGEGRMAFSNE-EQLERLIAGKLAPLRYVDDQGSPTESYPLNPNGSPRGVAALCSPDGRHLAMMPHPERCVLPWQWAWAPTA----WRGSVTTSPWLRLFSNARAW</Hsp_qseq>
      <Hsp_hseq>NGQMEMAWCFQQAGFNSVDVTMTDLLEGRFHLDDFIGLAACGGFSYGDVLGAGAGWAKSVLYHEGVRSQFSKFFNERQDTFAFGACNGCQFLSRLKDIIPGCENWPSFERNVSEQYEARVCMVQISQEKDNSSEESVFLNGMAGSKLPIAVAHGEGKATFSKSAEQLEKFEKDGLCCIRYVDNYGNVTERFPFNPNGSTNGIAGIKSPNGRVLAMMPHPERVCRLEANSWYPEGKYEEWGG---YGPWIRLFRSARRW</Hsp_hseq>
      <Hsp_midline>NG  EMA     AGF                 + F GL   GGFSY DVLG+  GWA SVL++          F  R DTF+ G           + + PG    P    NVS ++E+R   V++ ++        +  + +      + VAHGEG+  FS   EQLE+     L  +RYVD+ G+ TE +P NPNGS  G+A + SP+GR LAMMPHPER       +W P      W G     PW+RLF +AR W</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>101.679</Hsp_bit-score>
      <Hsp_score>252</Hsp_score>
      <Hsp_evalue>4.98334e-22</Hsp_evalue>
      <Hsp_query-from>1034</Hsp_query-from>
      <Hsp_query-to>1546</Hsp_query-to>
      <Hsp_hit-from>384</Hsp_hit-from>
      <Hsp_hit-to>556</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>176</Hsp_align-len>
      <Hsp_qseq>ELPWEDASFRYPGNFATPLEIAVEASNGASDYGNKFGEPLLAGFARSFGLRLPSGERCEWV----KPVMFSGGIGAIEDRHVGK-MPPEPGMAVVKMGGPAYRIXXXXXXXXXXEVQGDNSAELDLGAVQRGDAEMEQRMNRALRGCIEMGGDANPVLSIHDQGAGGNGNVLKELV</Hsp_qseq>
      <Hsp_hseq>EQPWE-LNIGKPYHIASALDIMIEAPLGSAAFNNEFGRPCINGYFRTLTTKVLNHQGKEEIRGFHKPIMIAGGFGTVRPQFALKNTPITPGSCLIVLGGQSMLIGLGGGAASSV-ASGEGSADLDFASVQRGNPEMERRCQQVIDACVALGNN-NPIQSIHDVGAGGLSNALPELV</Hsp_hseq>
      <Hsp_midline>E PWE  +   P + A+ L+I +EA  G++ + N+FG P + G+ R+   ++ + +  E +    KP+M +GG G +  +   K  P  PG  ++ +GG +  IG+GGGAASSV   G+ SA+LD  +VQRG+ EME+R  + +  C+ +G + NP+ SIHD GAGG  N L ELV</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>93.2041</Hsp_bit-score>
      <Hsp_score>230</Hsp_score>
      <Hsp_evalue>2.24619e-19</Hsp_evalue>
      <Hsp_query-from>1822</Hsp_query-from>
      <Hsp_query-to>2511</Hsp_query-to>
      <Hsp_hit-from>637</Hsp_hit-from>
      <Hsp_hit-to>910</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>85</Hsp_identity>
      <Hsp_positive>129</Hsp_positive>
      <Hsp_gaps>84</Hsp_gaps>
      <Hsp_align-len>294</Hsp_align-len>
      <Hsp_qseq>PVDLQLDWVLGKMPRKVPVHRRPTNIEQAMDCAGVEFVMAHENVALAPLRLPDGLSVRQALERVLRLPSVASKRYLT-------------NKCVGPLHTPLADVAVVAHSMCGTV---GAATSIGEQPIKGLVDPAAGARM-----------ADV------KCSGNWMWAAKLPGEGARLVTACRAM-CSCMRQLGIAVDGGKDSLSMAARVGSNTVKAP------------------------------GVLLHVSLGPARHRLGGSALAQCYGQIGDSSPDMDSPETVVAGF</Hsp_qseq>
      <Hsp_hseq>PIDLEMPILFGKPPK----MSRET-ITEALN-------LPEANLSEIP-------SLQDAIQRVLNLPSVGSKSFLITIGDRSVTGLIDRDQFVGPWQVPVADVGVTGTSLGETIISTGEAMAMGEKPVNALISASASAKLSVAESLLNIFAADVKSLNHIKLSANWMSPASHQGEGSKLYEAVQALGLDLCPALGVAIPVGKDSMSMKMKWDDKEVTAPLSLNITAFAPVFNTSKTWTPLLNRNTDDSVLVLVDLSAKQETKSLGASALLQVYNQVGNKSPTV-YDNAILKGF</Hsp_hseq>
      <Hsp_midline>P+DL++  + GK P+      R T I +A++       +   N++  P       S++ A++RVL LPSV SK +L              ++ VGP   P+ADV V   S+  T+   G A ++GE+P+  L+  +A A++           ADV      K S NWM  A   GEG++L  A +A+       LG+A+  GKDS+SM  +     V AP                               VL+ +S       LG SAL Q Y Q+G+ SP +     ++ GF</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>4</Hsp_num>
      <Hsp_bit-score>72.7886</Hsp_bit-score>
      <Hsp_score>177</Hsp_score>
      <Hsp_evalue>3.99456e-13</Hsp_evalue>
      <Hsp_query-from>324</Hsp_query-from>
      <Hsp_query-to>887</Hsp_query-to>
      <Hsp_hit-from>103</Hsp_hit-from>
      <Hsp_hit-to>297</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>206</Hsp_align-len>
      <Hsp_qseq>VLKRLNFSTAWSTNAVSICHSIGLH-HVKRIECSQRHLFKVHGEEAVSEQARRVLASGLHDRTTECVY-DHPLGSFALSVRTEP-----VWIT---------GVLRQARS--GLALDEWDLDYYTRLFRERVGRNPTSVECFDIAQSNRQAKPAPAQVIYEHSRHWLFRGRLTVDGQALEESLFDMIIGTQQHSNPNNVIKFSDNS</Hsp_qseq>
      <Hsp_hseq>VVPRSGTISPWSSKATNIAHVCGLQDKVQRIERGLALLIKTVPGFPLLENLNDISLKCVYDRMTQQLYLTEPPNTMSIFTHEEPKPLVHVPLTPKDTKQSPKDILSKANTELGLALDSGEMEYLIHAFVETMKRDPTDVELFMFAQVNS-----------EHCRHKIFNADWTIDGIKQQFTLFQMIRNTHKLNPEYTISAYSDNA</Hsp_hseq>
      <Hsp_midline>V+ R    + WS+ A +I H  GL   V+RIE     L K      + E    +    ++DR T+ +Y   P  + ++    EP     V +T          +L +A +  GLALD  +++Y    F E + R+PT VE F  AQ N            EH RH +F    T+DG   + +LF MI  T + +    +  +SDN+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>102</Statistics_hsp-len>
      <Statistics_eff-space>3005002647</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061662-RA transcript Note:&quot;Similar to Cyclic nucleotide-gated channel rod photoreceptor subunit alpha (Gallus gallus)&quot; offset:0 AED:0.12 eAED:0.13 QI:0|0|0|0.83|1|1|6|0|590</Iteration_query-def>
  <Iteration_query-len>1773</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1134385232</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0034604-RA transcript Note:&quot;Similar to ATP8A1 Phospholipid-transporting ATPase IA (Homo sapiens)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.45|0.44|25|1984|299</Iteration_query-def>
  <Iteration_query-len>2884</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YER166W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:512744:517459:1 gene:YER166W transcript:YER166W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DNF1 description:Aminophospholipid translocase (flippase); type 4 P-type ATPase; involved in phospholipid translocation, contributing to endocytosis, protein transport, and cellular polarization; localizes primarily to the plasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; DNF1 has a paralog, DNF2, that arose from the whole genome duplication [Source:SGD;Acc:S000000968]</Hit_def>
  <Hit_accession>YER166W</Hit_accession>
  <Hit_len>1571</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>125.176</Hsp_bit-score>
      <Hsp_score>313</Hsp_score>
      <Hsp_evalue>8.0944e-44</Hsp_evalue>
      <Hsp_query-from>939</Hsp_query-from>
      <Hsp_query-to>1412</Hsp_query-to>
      <Hsp_hit-from>954</Hsp_hit-from>
      <Hsp_hit-to>1166</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>114</Hsp_positive>
      <Hsp_gaps>55</Hsp_gaps>
      <Hsp_align-len>213</Hsp_align-len>
      <Hsp_qseq>DLLLLGATAIEDKLQDGVPETIATLIRANIRIWVLTGDKQETAINIGYSTRLLNQDMGLVIINESSKDATR----------AELTAQLEDLGEQVNRENDL--------------ALIVDGKSLKSEIV-DAVKKKV-------------------RAAI-----------TLAVGDGANDVGMIKTAHVGVGISGNEGLQAVNSSDYSIAQV</Hsp_qseq>
      <Hsp_hseq>ELILLGGTAIEDRLQDGVPDCIELLAEAGIKLWVLTGDKVETAINIGFSCNLLNNEMELLVIKTTGDDVKEFGSEPSEIVDALLSKYLKEYFNLTGSEEEIFEAKKDHEFPKGNYAIVIDGDALKLALYGEDIRRKFLLLCKNCRAVLCCRVSPSQKAAVVKLVKDSLDVMTLAIGDGSNDVAMIQSADVGIGIAGEEGRQAVMCSDYAIGQF</Hsp_hseq>
      <Hsp_midline>+L+LLG TAIED+LQDGVP+ I  L  A I++WVLTGDK ETAINIG+S  LLN +M L++I  +  D             A L+  L++       E ++              A+++DG +LK  +  + +++K                    +AA+           TLA+GDG+NDV MI++A VG+GI+G EG QAV  SDY+I Q </Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>46.2098</Hsp_bit-score>
      <Hsp_score>108</Hsp_score>
      <Hsp_evalue>8.0944e-44</Hsp_evalue>
      <Hsp_query-from>1421</Hsp_query-from>
      <Hsp_query-to>1537</Hsp_query-to>
      <Hsp_hit-from>1160</Hsp_hit-from>
      <Hsp_hit-to>1198</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>19</Hsp_identity>
      <Hsp_positive>27</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>39</Hsp_align-len>
      <Hsp_qseq>DVGVSQFCHLKKLLLVHGAWSYTRVAKCILYSFYKNVVL</Hsp_qseq>
      <Hsp_hseq>DYAIGQFRYLARLVLVHGRWSYKRLAEMIPEFFYKNMIF</Hsp_hseq>
      <Hsp_midline>D  + QF +L +L+LVHG WSY R+A+ I   FYKN++ </Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>45.0542</Hsp_bit-score>
      <Hsp_score>105</Hsp_score>
      <Hsp_evalue>8.0944e-44</Hsp_evalue>
      <Hsp_query-from>1591</Hsp_query-from>
      <Hsp_query-to>1770</Hsp_query-to>
      <Hsp_hit-from>1229</Hsp_hit-from>
      <Hsp_hit-to>1288</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>34</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>60</Hsp_align-len>
      <Hsp_qseq>FTALPPFVLGIFERSCSQDSMLRFPALYKQSQNAEEFNSRIFWIHCLNGLFHSVVLFWIP</Hsp_qseq>
      <Hsp_hseq>FTSLPVIFLGILDQDVNDTISLVVPQLYRVGILRKEWNQRKFLWYMLDGLYQSIICFFFP</Hsp_hseq>
      <Hsp_midline>FT+LP   LGI ++  +    L  P LY+     +E+N R F  + L+GL+ S++ F+ P</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>4</Hsp_num>
      <Hsp_bit-score>117.087</Hsp_bit-score>
      <Hsp_score>292</Hsp_score>
      <Hsp_evalue>6.09684e-27</Hsp_evalue>
      <Hsp_query-from>229</Hsp_query-from>
      <Hsp_query-to>675</Hsp_query-to>
      <Hsp_hit-from>401</Hsp_hit-from>
      <Hsp_hit-to>564</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>167</Hsp_align-len>
      <Hsp_qseq>VAVGDLVKVTNGQHLPADLILLSSSEPQGMCYIETSSLDGETNLKIRQPAAASGR-------------IECEPPNRFLYDFMGNI---NL-DGH-SPQPLGPDQVLLRGAQLRNTQWVVGVTVYTGHDTKLMQSDTPAMARTSNLNEELGQPTSAVIRDFLTMMAVC</Hsp_qseq>
      <Hsp_hseq>VKVGDIVRIHNNDEIPADIILLSTSDTDGACYVETKNLDGETNLKVRQSLKCTNTIRTSKDIARTKFWIESEGPHSNLYTYQGNMKWRNLADGEIRNEPITINNVLLRGCTLRNTKWAMGVVMFTGGDTKIMLNSGITPTKKSRISREL---NFSVVINFVLLFILC</Hsp_hseq>
      <Hsp_midline>V VGD+V++ N   +PAD+ILLS+S+  G CY+ET +LDGETNLK+RQ    +               IE E P+  LY + GN+   NL DG    +P+  + VLLRG  LRNT+W +GV ++TG DTK+M +      + S ++ EL     +V+ +F+ +  +C</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>5</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>2.33095e-11</Hsp_evalue>
      <Hsp_query-from>652</Hsp_query-from>
      <Hsp_query-to>867</Hsp_query-to>
      <Hsp_hit-from>770</Hsp_hit-from>
      <Hsp_hit-to>844</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>53</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>75</Hsp_align-len>
      <Hsp_qseq>FLTMMAVCHTVIPERSEGS---IIYQATSPDESALVRAAKDMGFTFCGRTPDSIIIDALGKEETYKLLNVLEFSS</Hsp_qseq>
      <Hsp_hseq>FMLALALCHSVLVEANPDNPKKLDLKAQSPDEAALVATARDVGFSFVGKTKKGLIIEMQGIQKEFEILNILEFNS</Hsp_hseq>
      <Hsp_midline>F+  +A+CH+V+ E +  +   +  +A SPDE+ALV  A+D+GF+F G+T   +II+  G ++ +++LN+LEF+S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YDR093W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:631282:636120:1 gene:YDR093W transcript:YDR093W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DNF2 description:Aminophospholipid translocase (flippase); type 4 P-type ATPase; involved in phospholipid translocation, contributing to endocytosis, protein transport, and cellular polarization; localizes primarily to the plasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; DNF2 has a paralog, DNF1, that arose from the whole genome duplication [Source:SGD;Acc:S000002500]</Hit_def>
  <Hit_accession>YDR093W</Hit_accession>
  <Hit_len>1612</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>131.339</Hsp_bit-score>
      <Hsp_score>329</Hsp_score>
      <Hsp_evalue>1.83738e-43</Hsp_evalue>
      <Hsp_query-from>939</Hsp_query-from>
      <Hsp_query-to>1412</Hsp_query-to>
      <Hsp_hit-from>997</Hsp_hit-from>
      <Hsp_hit-to>1209</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>85</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>59</Hsp_gaps>
      <Hsp_align-len>215</Hsp_align-len>
      <Hsp_qseq>DLLLLGATAIEDKLQDGVPETIATLIRANIRIWVLTGDKQETAINIGYSTRLLNQDMGLVIINESSKDA--------------------TRAELTAQLEDLGEQVNREN-----DLALIVDGKSL--------------------------------KSEIVDAVKKKVRAAITLAVGDGANDVGMIKTAHVGVGISGNEGLQAVNSSDYSIAQV</Hsp_qseq>
      <Hsp_hseq>ELILLGGTAIEDRLQDGVPDSIALLAEAGIKLWVLTGDKVETAINIGFSCNVLNNDMELLVVKASGEDVEEFGSDPIQVVNNLVTKYLREKFGMSGSEEELKE-AKREHGLPQGNFAVIIDGDALKVALNGEEMRRKFLLLCKNCKAVLCCRVSPAQKAAVVKLVKKTL-DVMTLAIGDGSNDVAMIQSADVGVGIAGEEGRQAVMCSDYAIGQF</Hsp_hseq>
      <Hsp_midline>+L+LLG TAIED+LQDGVP++IA L  A I++WVLTGDK ETAINIG+S  +LN DM L+++  S +D                      +  ++   E+L E   RE+     + A+I+DG +L                                K+ +V  VKK +   +TLA+GDG+NDV MI++A VGVGI+G EG QAV  SDY+I Q </Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>44.669</Hsp_bit-score>
      <Hsp_score>104</Hsp_score>
      <Hsp_evalue>1.83738e-43</Hsp_evalue>
      <Hsp_query-from>1421</Hsp_query-from>
      <Hsp_query-to>1537</Hsp_query-to>
      <Hsp_hit-from>1203</Hsp_hit-from>
      <Hsp_hit-to>1241</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>18</Hsp_identity>
      <Hsp_positive>26</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>39</Hsp_align-len>
      <Hsp_qseq>DVGVSQFCHLKKLLLVHGAWSYTRVAKCILYSFYKNVVL</Hsp_qseq>
      <Hsp_hseq>DYAIGQFRYVTRLVLVHGKWCYKRLAEMIPQFFYKNVIF</Hsp_hseq>
      <Hsp_midline>D  + QF ++ +L+LVHG W Y R+A+ I   FYKNV+ </Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>38.891</Hsp_bit-score>
      <Hsp_score>89</Hsp_score>
      <Hsp_evalue>1.83738e-43</Hsp_evalue>
      <Hsp_query-from>1591</Hsp_query-from>
      <Hsp_query-to>1779</Hsp_query-to>
      <Hsp_hit-from>1272</Hsp_hit-from>
      <Hsp_hit-to>1334</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>18</Hsp_identity>
      <Hsp_positive>34</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>63</Hsp_align-len>
      <Hsp_qseq>FTALPPFVLGIFERSCSQDSMLRFPALYKQSQNAEEFNSRIFWIHCLNGLFHSVVLFWIPLKA</Hsp_qseq>
      <Hsp_hseq>FTSVPVILLAVLDQDVSDTVSMLVPQLYRVGILRKEWNQTKFLWYMLDGVYQSVICFFFPYLA</Hsp_hseq>
      <Hsp_midline>FT++P  +L + ++  S    +  P LY+     +E+N   F  + L+G++ SV+ F+ P  A</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>4</Hsp_num>
      <Hsp_bit-score>115.931</Hsp_bit-score>
      <Hsp_score>289</Hsp_score>
      <Hsp_evalue>1.28444e-26</Hsp_evalue>
      <Hsp_query-from>220</Hsp_query-from>
      <Hsp_query-to>681</Hsp_query-to>
      <Hsp_hit-from>440</Hsp_hit-from>
      <Hsp_hit-to>611</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>175</Hsp_align-len>
      <Hsp_qseq>EDY---VAVGDLVKVTNGQHLPADLILLSSSEPQGMCYIETSSLDGETNLKIRQPAAASGRI-------------ECEPPNRFLYDFMGNIN----LDGH-SPQPLGPDQVLLRGAQLRNTQWVVGVTVYTGHDTKLMQSDTPAMARTSNLNEELGQPTSAVIRDFLTMMAVCHT</Hsp_qseq>
      <Hsp_hseq>KDYWKNVKVGDIVRVHNNDEIPADMILLSTSDVDGACYVETKNLDGETNLKVRQSLKCSKIIKSSRDITRTKFWVESEGPHANLYSYQGNFKWQDTQNGNIRNEPVNINNLLLRGCTLRNTKWAMGMVIFTGDDTKIMINAGVTPTKKSRISREL---NFSVILNFVLLFILCFT</Hsp_hseq>
      <Hsp_midline>+DY   V VGD+V+V N   +PAD+ILLS+S+  G CY+ET +LDGETNLK+RQ    S  I             E E P+  LY + GN       +G+   +P+  + +LLRG  LRNT+W +G+ ++TG DTK+M +      + S ++ EL     +VI +F+ +  +C T</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>5</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>3.43594e-10</Hsp_evalue>
      <Hsp_query-from>652</Hsp_query-from>
      <Hsp_query-to>867</Hsp_query-to>
      <Hsp_hit-from>815</Hsp_hit-from>
      <Hsp_hit-to>889</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>75</Hsp_align-len>
      <Hsp_qseq>FLTMMAVCHTVIPERSEGS---IIYQATSPDESALVRAAKDMGFTFCGRTPDSIIIDALGKEETYKLLNVLEFSS</Hsp_qseq>
      <Hsp_hseq>FLLALALCHSVLVEPNKDDPKKLDIKAQSPDESALVSTARQLGYSFVGSSKSGLIVEIQGVQKEFQVLNVLEFNS</Hsp_hseq>
      <Hsp_midline>FL  +A+CH+V+ E ++     +  +A SPDESALV  A+ +G++F G +   +I++  G ++ +++LNVLEF+S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YAL026C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:95630:99697:-1 gene:YAL026C transcript:YAL026C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DRS2 description:Trans-golgi network aminophospholipid translocase (flippase); maintains membrane lipid asymmetry in post-Golgi secretory vesicles; contributes to clathrin-coated vesicle formation, endocytosis, protein trafficking between the Golgi and endosomal system and the cellular response to mating pheromone; autoinhibited by its C-terminal tail; localizes to the trans-Golgi network; mutations in human homolog ATP8B1 result in liver disease [Source:SGD;Acc:S000000024]</Hit_def>
  <Hit_accession>YAL026C</Hit_accession>
  <Hit_len>1355</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>168.703</Hsp_bit-score>
      <Hsp_score>426</Hsp_score>
      <Hsp_evalue>4.35547e-43</Hsp_evalue>
      <Hsp_query-from>28</Hsp_query-from>
      <Hsp_query-to>582</Hsp_query-to>
      <Hsp_hit-from>204</Hsp_hit-from>
      <Hsp_hit-to>431</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>97</Hsp_identity>
      <Hsp_positive>139</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>229</Hsp_align-len>
      <Hsp_qseq>TTAKYNVVTFLPRFLFEQFRKXXXXXXXXXXXXXXXPDVSPTGRYTTLVPLIFILTLAAIKELIEDY-------------------------------VAVGDLVKVTNGQHLPADLILLSSSEPQGMCYIETSSLDGETNLKIRQPAAAS-------------GRIECEPPNRFLYDFMGNINLDGHSPQPLGPDQVLLRGAQLRNTQWVVGVTVYTGHDTKLMQSDT</Hsp_qseq>
      <Hsp_hseq>STTKYNFATFLPKFLFQEFSKYANLFFLCTSAIQQVPHVSPTNRYTTIGTLLVVLIVSAMKECIEDIKRANSDKELNNSTAEIFSEAHDDFVEKRWIDIRVGDIIRVKSEEPIPADTIILSSSEPEGLCYIETANLDGETNLKIKQSRVETAKFIDVKTLKNMNGKVVSEQPNSSLYTYEGTMTLNDRQI-PLSPDQMILRGATLRNTAWIFGLVIFTGHETKLLRNAT</Hsp_hseq>
      <Hsp_midline>+T KYN  TFLP+FLF++F K AN FFL  + +QQ+P VSPT RYTT+  L+ +L ++A+KE IED                                + VGD+++V + + +PAD I+LSSSEP+G+CYIET++LDGETNLKI+Q    +             G++  E PN  LY + G + L+     PL PDQ++LRGA LRNT W+ G+ ++TGH+TKL+++ T</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>167.548</Hsp_bit-score>
      <Hsp_score>423</Hsp_score>
      <Hsp_evalue>1.04252e-42</Hsp_evalue>
      <Hsp_query-from>939</Hsp_query-from>
      <Hsp_query-to>1412</Hsp_query-to>
      <Hsp_hit-from>800</Hsp_hit-from>
      <Hsp_hit-to>990</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>95</Hsp_identity>
      <Hsp_positive>122</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>192</Hsp_align-len>
      <Hsp_qseq>DLLLLGATAIEDKLQDGVPETIATLIRANIRIWVLTGDKQETAINIGYSTRLLNQDMGLVIINESSKDATRAELTAQLEDLGEQ---VNRENDLALIVDGKSL-------------------------------KSEIVDAVKKKVRAAITLAVGDGANDVGMIKTAHVGVGISGNEGLQAVNSSDYSIAQV</Hsp_qseq>
      <Hsp_hseq>NLILIGATAIEDKLQDGVPETIHTLQEAGIKIWVLTGDRQETAINIGMSCRLLSEDMNLLIINEETRDDTERNLLEKINALNEHQLSTHDMNTLALVIDGKSLGFALEPELEDYLLTVAKLCKAVICCRVSPLQKALVVKMVKRK-SSSLLLAIGDGANDVSMIQAAHVGVGISGMEGMQAARSADIAVGQF</Hsp_hseq>
      <Hsp_midline>+L+L+GATAIEDKLQDGVPETI TL  A I+IWVLTGD+QETAINIG S RLL++DM L+IINE ++D T   L  ++  L E     +  N LAL++DGKSL                               K+ +V  VK+K  +++ LA+GDGANDV MI+ AHVGVGISG EG+QA  S+D ++ Q </Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>106.301</Hsp_bit-score>
      <Hsp_score>264</Hsp_score>
      <Hsp_evalue>6.39882e-37</Hsp_evalue>
      <Hsp_query-from>1588</Hsp_query-from>
      <Hsp_query-to>2385</Hsp_query-to>
      <Hsp_hit-from>1052</Hsp_hit-from>
      <Hsp_hit-to>1299</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>125</Hsp_positive>
      <Hsp_gaps>78</Hsp_gaps>
      <Hsp_align-len>296</Hsp_align-len>
      <Hsp_qseq>MFTALPPFVLGIFERSCSQDSMLRFPALYKQSQNAEEFNSRIFWIHCLNGLFHSVVLF------------------------W---IPLKAVEHVCLKAGLETTAWTRLSHIAVWGSIALWVVFFGIYSLLWPAIPLAPDMSGQASMMLKSGVFWMALILIPI-TVRRSCFQSLVEEVQESEARAQKSDRIMLTSILNKRHKPRGGDXXXXXXXXXXXXXXXXXXPTSLVPTSSFTERAHL--LRNAFKKTSPEFGNTKSSVRRDFMHGYAFSQEENGVLSQTEVVRAYDTTRQQG</Hsp_qseq>
      <Hsp_hseq>FFTVWPPFVIGVFDQFVSSRLLERYPQLYKLGQKGQFFSVYIFWGWIINGFFHSAIVFIGTILIYRYGFALNMHGELADHWSWGVTVYTTSVIIVLGKAALVTNQWTKFTLIAIPGSLLFWLIFFPIYASIFPHANISREYYGVVKHTYGSGVFWLTLIVLPIFALVRDFLWKYYKRMYEPETY----------HVIQEMQKYNISDS-----------------------------RPHVQQFQNAIRK-------VRQVQRMKKQRGFAFSQAEEG--GQEKIVRMYDTTQKRG</Hsp_hseq>
      <Hsp_midline> FT  PPFV+G+F++  S   + R+P LYK  Q  + F+  IFW   +NG FHS ++F                        W   +   +V  V  KA L T  WT+ + IA+ GS+  W++FF IY+ ++P   ++ +  G       SGVFW+ LI++PI  + R       + + E E             ++ +  K    D+                             R H+   +NA +K        +   R     G+AFSQ E G   Q ++VR YDTT+++G</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>4</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>6.39882e-37</Hsp_evalue>
      <Hsp_query-from>1403</Hsp_query-from>
      <Hsp_query-to>1561</Hsp_query-to>
      <Hsp_hit-from>978</Hsp_hit-from>
      <Hsp_hit-to>1030</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>37</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>53</Hsp_align-len>
      <Hsp_qseq>RAGGVCDVGVSQFCHLKKLLLVHGAWSYTRVAKCILYSFYKNVVLYIIEIFTV</Hsp_qseq>
      <Hsp_hseq>QAARSADIAVGQFKFLKKLLLVHGSWSYQRISVAILYSFYKNTALYMTQFWYV</Hsp_hseq>
      <Hsp_midline>+A    D+ V QF  LKKLLLVHG+WSY R++  ILYSFYKN  LY+ + + V</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>5</Hsp_num>
      <Hsp_bit-score>93.9745</Hsp_bit-score>
      <Hsp_score>232</Hsp_score>
      <Hsp_evalue>6.94142e-20</Hsp_evalue>
      <Hsp_query-from>595</Hsp_query-from>
      <Hsp_query-to>867</Hsp_query-to>
      <Hsp_hit-from>604</Hsp_hit-from>
      <Hsp_hit-to>700</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>97</Hsp_align-len>
      <Hsp_qseq>RTSNLNEELGQPT---SAVIRDFLTMMAVCHTVIPE-RSEGSIIYQATSPDESALVRAAKDMGFTFCGRTPDS--IIIDALGKEETYKLLNVLEFSS</Hsp_qseq>
      <Hsp_hseq>KFDDLKKKLNDPSDEDSPIINDFLTLLATCHTVIPEFQSDGSIKYQAASPDEGALVQGGADLGYKFIIRKPNSVTVLLEETGEEKEYQLLNICEFNS</Hsp_hseq>
      <Hsp_midline>+  +L ++L  P+   S +I DFLT++A CHTVIPE +S+GSI YQA SPDE ALV+   D+G+ F  R P+S  ++++  G+E+ Y+LLN+ EF+S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YMR162C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:578951:583921:-1 gene:YMR162C transcript:YMR162C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DNF3 description:Trans-golgi network aminophospholipid translocase (flippase); type 4 P-type ATPase; involved in phospholipid translocation, contributing to the maintenance of membrane lipid asymmetry in post-Golgi secretory vesicles; role in protein trafficking between the Golgi and endosomal system; localizes to the trans-Golgi network; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone [Source:SGD;Acc:S000004772]</Hit_def>
  <Hit_accession>YMR162C</Hit_accession>
  <Hit_len>1656</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>119.013</Hsp_bit-score>
      <Hsp_score>297</Hsp_score>
      <Hsp_evalue>1.57808e-27</Hsp_evalue>
      <Hsp_query-from>942</Hsp_query-from>
      <Hsp_query-to>1412</Hsp_query-to>
      <Hsp_hit-from>1080</Hsp_hit-from>
      <Hsp_hit-to>1265</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>191</Hsp_align-len>
      <Hsp_qseq>LLLLGATAIEDKLQDGVPETIATLIRANIRIWVLTGDKQETAINIGYSTRLLNQDMGLVIINESSKDATRAELTAQLEDLGEQVNREN--DLALIVDGKSL--------------------------------KSEIVDAVKKKVRAAITLAVGDGANDVGMIKTAHVGVGISGNEGLQAVNSSDYSIAQV</Hsp_qseq>
      <Hsp_hseq>LNLLGVTAIEDKLQDGVSEAIEKIRRAGIKMWMLTGDKRETAINIGYSCMLIKDYSTVVILT-----TTDENIISKMNAVSQEVDSGNIAHCVVVIDGATMAMFEGNPTYMSVFVELCTKTDSVICCRASPSQKALMVSNIRNTDPNLVTLAIGDGANDIAMIQSADIGVGIAGKEGLQASRVSDYSIGQF</Hsp_hseq>
      <Hsp_midline>L LLG TAIEDKLQDGV E I  + RA I++W+LTGDK+ETAINIGYS  L+     +VI+       T   + +++  + ++V+  N     +++DG ++                                K+ +V  ++      +TLA+GDGAND+ MI++A +GVGI+G EGLQA   SDYSI Q </Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>105.145</Hsp_bit-score>
      <Hsp_score>261</Hsp_score>
      <Hsp_evalue>2.81849e-23</Hsp_evalue>
      <Hsp_query-from>235</Hsp_query-from>
      <Hsp_query-to>567</Hsp_query-to>
      <Hsp_hit-from>304</Hsp_hit-from>
      <Hsp_hit-to>433</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>130</Hsp_align-len>
      <Hsp_qseq>VGDLVKVTNGQHLPADLILLSSSEPQGMCYIETSSLDGETNLKIRQP--------AAASG------RIECEPPNRFLYDFMGNINLDGHSPQ-----PLGPDQVLLRGAQLRNTQWVVGVTVYTGHDTKL</Hsp_qseq>
      <Hsp_hseq>VGDFVLLTQDDWVPADLLLLTCDGENSECFVETMALDGETNLKSKQPHPELNKLTKAASGLANINAQVTVEDPNIDLYNFEGNLELKNHRNDTIMKYPLGPDNVIYRGSILRNTQNVVGMVIFSGEETKI</Hsp_hseq>
      <Hsp_midline>VGD V +T    +PADL+LL+       C++ET +LDGETNLK +QP         AASG      ++  E PN  LY+F GN+ L  H        PLGPD V+ RG+ LRNTQ VVG+ +++G +TK+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>1.6964e-09</Hsp_evalue>
      <Hsp_query-from>652</Hsp_query-from>
      <Hsp_query-to>870</Hsp_query-to>
      <Hsp_hit-from>731</Hsp_hit-from>
      <Hsp_hit-to>816</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>86</Hsp_align-len>
      <Hsp_qseq>FLTMMAVCHTVIPERS------EGSIIYQATSPDESALVRAAKDMGFTFCGRTPDSIII-------DALGKEETYKLLNVLEFSSE</Hsp_qseq>
      <Hsp_hseq>FFLSLALCHSCLPKKTHNESIGEDSIEYQSSSPDELALVTAARDLGYIVLNRNAQILTIKTFPDGFDGEAKLENYEILNYIDFNSQ</Hsp_hseq>
      <Hsp_midline>F   +A+CH+ +P+++      E SI YQ++SPDE ALV AA+D+G+    R    + I       D   K E Y++LN ++F+S+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>4</Hsp_num>
      <Hsp_bit-score>45.8246</Hsp_bit-score>
      <Hsp_score>107</Hsp_score>
      <Hsp_evalue>2.41217e-09</Hsp_evalue>
      <Hsp_query-from>1403</Hsp_query-from>
      <Hsp_query-to>1552</Hsp_query-to>
      <Hsp_hit-from>1253</Hsp_hit-from>
      <Hsp_hit-to>1302</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>20</Hsp_identity>
      <Hsp_positive>30</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>50</Hsp_align-len>
      <Hsp_qseq>RAGGVCDVGVSQFCHLKKLLLVHGAWSYTRVAKCILYSFYKNVVLYIIEI</Hsp_qseq>
      <Hsp_hseq>QASRVSDYSIGQFRFLLKLLFVHGRYNYIRTSKFMLCTFYKEITFYFTQL</Hsp_hseq>
      <Hsp_midline>+A  V D  + QF  L KLL VHG ++Y R +K +L +FYK +  Y  ++</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>5</Hsp_num>
      <Hsp_bit-score>33.4982</Hsp_bit-score>
      <Hsp_score>75</Hsp_score>
      <Hsp_evalue>2.41217e-09</Hsp_evalue>
      <Hsp_query-from>1588</Hsp_query-from>
      <Hsp_query-to>1722</Hsp_query-to>
      <Hsp_hit-from>1327</Hsp_hit-from>
      <Hsp_hit-to>1373</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>16</Hsp_identity>
      <Hsp_positive>27</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>47</Hsp_align-len>
      <Hsp_qseq>MFTALPPFVLGIFERSCSQDSMLRFPALYKQSQNAEEFNSRIF--WI</Hsp_qseq>
      <Hsp_hseq>LFTSLPVLCIGMFEKDLKPMTLLTVPELYSYGRLSQGFNWLIFMEWV</Hsp_hseq>
      <Hsp_midline>+FT+LP   +G+FE+     ++L  P LY   + ++ FN  IF  W+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YIL048W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:261437:264892:1 gene:YIL048W transcript:YIL048W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NEO1 description:Phospholipid translocase (flippase), role in phospholipid asymmetry of plasma membrane; involved in endocytosis, vacuolar biogenesis and Golgi to ER vesicle-mediated transport; localizes to endosomes and the Golgi apparatus [Source:SGD;Acc:S000001310]</Hit_def>
  <Hit_accession>YIL048W</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>103.605</Hsp_bit-score>
      <Hsp_score>257</Hsp_score>
      <Hsp_evalue>6.63437e-23</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>624</Hsp_query-to>
      <Hsp_hit-from>169</Hsp_hit-from>
      <Hsp_hit-to>412</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>79</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>244</Hsp_align-len>
      <Hsp_qseq>RFQGATGTTAKYNVVTFLPRFLFEQFRKXXXXXXXXXXXXXXXPDVSPTGRYTTLVPLIFILTLAAIKELI--------------EDY-------------VAVGDLVKVTNGQHLPADLILLSSSEPQGMCYIETSSLDGETNLKIR------QPAAASGRIE-----CEPPNRFLYDFMGNINLDGHSPQPLGPDQVLLRGAQLRNTQWVVGVTVYTGHDTKLMQSDTPAMARTSNLNEELG</Hsp_qseq>
      <Hsp_hseq>RYVSNELSNAKYNAVTFVPTLLYEQFKFFYNLYFLVVALSQAVPALRIGYLSSYIVPLAFVLTVTMAKEAIDDIQRRRRDRESNNELYHVITRNRSIPSKDLKVGDLIKVHKGDRIPADLVLLQSSEPSGESFIKTDQLDGETDWKLRVACPLTQNLSENDLINRISITASAPEKSIHKFLGKVTYKDSTSNPLSVDNTLWANTVLASSGFCIACVVYTGRDTRQAMNTTTAKVKTGLLELEIN</Hsp_hseq>
      <Hsp_midline>R+     + AKYN VTF+P  L+EQF+   N +FL++AL Q +P +      + +VPL F+LT+   KE I              E Y             + VGDL+KV  G  +PADL+LL SSEP G  +I+T  LDGET+ K+R      Q  + +  I         P + ++ F+G +     +  PL  D  L     L ++ + +   VYTG DT+   + T A  +T  L  E+ </Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>93.5893</Hsp_bit-score>
      <Hsp_score>231</Hsp_score>
      <Hsp_evalue>7.74479e-20</Hsp_evalue>
      <Hsp_query-from>939</Hsp_query-from>
      <Hsp_query-to>1436</Hsp_query-to>
      <Hsp_hit-from>739</Hsp_hit-from>
      <Hsp_hit-to>920</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>196</Hsp_align-len>
      <Hsp_qseq>DLLLLGATAIEDKLQDGVPETIATLIRANIRIWVLTGDKQETAINIGYSTRLLNQDMGLVIINESSKDATRAE-LTAQLEDLGEQVNRENDLALIVDGKSL-------KSEIVDAV-------------KKKVRAAITL---------AVGDGANDVGMIKTAHVGVGISGNEGLQAVNSSDYSIAQVVSAMWACH</Hsp_qseq>
      <Hsp_hseq>DLELLGLTGVEDKLQKDVKSSIELLRNAGIKIWMLTGDKVETARCVSISAKLISRGQYVHTITK----VTRPEGAFNQLEYL--KINR--NACLLIDGESLGMFLKHYEQEFFDVVVHLPTVIACRCTPQQKADVALVIRKMTGKRVCCIGDGGNDVSMIQCADVGVGIVGKEGKQASLAADFSITQF------CH</Hsp_hseq>
      <Hsp_midline>DL LLG T +EDKLQ  V  +I  L  A I+IW+LTGDK ETA  +  S +L+++   +  I +     TR E    QLE L  ++NR  +  L++DG+SL       + E  D V             ++K   A+ +          +GDG NDV MI+ A VGVGI G EG QA  ++D+SI Q       CH</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>3.06351e-08</Hsp_evalue>
      <Hsp_query-from>643</Hsp_query-from>
      <Hsp_query-to>870</Hsp_query-to>
      <Hsp_hit-from>566</Hsp_hit-from>
      <Hsp_hit-to>643</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>44</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>78</Hsp_align-len>
      <Hsp_qseq>IRDFLTMMAVCHTVIPERSEGSIIYQATSPDESALVRAAKDMGFTFCGRTPDSI--IIDALGKEETYKLLNVLEFSSE</Hsp_qseq>
      <Hsp_hseq>VRDMILTLAICHNVTPTFEDDELTYQAASPDEIAIVKFTESVGLSLFKRDRHSISLLHEHSGKTLNYEILQVFPFNSD</Hsp_hseq>
      <Hsp_midline>+RD +  +A+CH V P   +  + YQA SPDE A+V+  + +G +   R   SI  + +  GK   Y++L V  F+S+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>1948694954</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061653-RA transcript Note:&quot;Similar to GUCY1B1 Guanylate cyclase soluble subunit beta-1 (Bos taurus)&quot; offset:0 AED:0.22 eAED:0.23 QI:0|0|0|0.81|1|1|11|0|491</Iteration_query-def>
  <Iteration_query-len>1476</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>912879466</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061656-RA transcript Note:&quot;Similar to Nup58 Nucleoporin p58/p45 (Rattus norvegicus)&quot; offset:162 AED:0.05 eAED:0.05 QI:162|0.92|0.86|1|0.57|0.46|15|2127|579</Iteration_query-def>
  <Iteration_query-len>4029</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>102</Statistics_hsp-len>
      <Statistics_eff-space>2780915947</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061657-RA transcript Note:&quot;Similar to TRPC3 Short transient receptor potential channel 3 (Homo sapiens)&quot; offset:0 AED:0.32 eAED:0.37 QI:0|0.3|0.36|1|1|1|11|0|660</Iteration_query-def>
  <Iteration_query-len>1983</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1288463855</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061661-RA transcript Note:&quot;Similar to fam160a2 FTS and Hook-interacting protein homolog (Danio rerio)&quot; offset:0 AED:0.24 eAED:0.24 QI:0|0|0|0.84|1|1|13|0|1076</Iteration_query-def>
  <Iteration_query-len>3231</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2202223459</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061663-RA transcript Note:&quot;Similar to cyfip1 Cytoplasmic FMR1-interacting protein 1 homolog (Danio rerio)&quot; offset:0 AED:0.48 eAED:0.48 QI:0|0|0|1|1|1|2|0|88</Iteration_query-def>
  <Iteration_query-len>267</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>60</Statistics_hsp-len>
      <Statistics_eff-space>73023943</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061664-RA transcript Note:&quot;Similar to CYFIP1 Cytoplasmic FMR1-interacting protein 1 (Homo sapiens)&quot; offset:0 AED:0.32 eAED:0.32 QI:0|0.05|0.11|0.88|0.94|0.94|18|0|688</Iteration_query-def>
  <Iteration_query-len>2067</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1352316931</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061665-RA transcript Note:&quot;Similar to CYFIP2 Cytoplasmic FMR1-interacting protein 2 (Homo sapiens)&quot; offset:0 AED:0.41 eAED:0.41 QI:0|0.4|0.33|1|1|1|6|0|554</Iteration_query-def>
  <Iteration_query-len>1665</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YLR330W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:787664:789679:1 gene:YLR330W transcript:YLR330W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHS5 description:Component of the exomer complex; the exomer which also contains Csh6p, Bch1p, Bch2p, and Bud7, is involved in the export of select proteins, such as chitin synthase Chs3p, from the Golgi to the plasma membrane; interacts selectively with the activated, GTP-bound form of Arf1p; Chs5p is the only protein with a BRCT domain that is not localized to the nucleus [Source:SGD;Acc:S000004322]</Hit_def>
  <Hit_accession>YLR330W</Hit_accession>
  <Hit_len>671</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>2.33061e-08</Hsp_evalue>
      <Hsp_query-from>390</Hsp_query-from>
      <Hsp_query-to>671</Hsp_query-to>
      <Hsp_hit-from>454</Hsp_hit-from>
      <Hsp_hit-to>545</Hsp_hit-to>
      <Hsp_query-frame>-2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>36</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>94</Hsp_align-len>
      <Hsp_qseq>TLNTPVRTLNTPVRTLNTSVITLNAPVVTLNTPVRTLNTPVRTLNTPVRTLNTSVITLNAPVVTLNTPVRTLNTPVRTLNTPVRTLNTSVVMLN</Hsp_qseq>
      <Hsp_hseq>EFGRPEAEIETP--EVNESIEDANEPAEDSNEPVEDSNKPVKDSNKPVEDSNKPVEDSNKPVEDSNKPVEDANEPVEDTSEPVEDAGEPVQETN</Hsp_hseq>
      <Hsp_midline>    P   + TP   +N S+   N P    N PV   N PV+  N PV   N  V   N PV   N PV   N PV   + PV      V   N</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>1.11179e-07</Hsp_evalue>
      <Hsp_query-from>345</Hsp_query-from>
      <Hsp_query-to>623</Hsp_query-to>
      <Hsp_hit-from>449</Hsp_hit-from>
      <Hsp_hit-to>546</Hsp_hit-to>
      <Hsp_query-frame>-2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>36</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>98</Hsp_align-len>
      <Hsp_qseq>NTSVITLNAPVVTLNTP-----VRTLNTPVRTLNTPVRTLNTSVITLNAPVVTLNTPVRTLNTPVRTLNTPVRTLNTSVVMLNAPVVTLNAPVRTLNT</Hsp_qseq>
      <Hsp_hseq>DDAAMEFGRPEAEIETPEVNESIEDANEPAEDSNEPVEDSNKPVKDSNKPVEDSNKPVEDSNKPVEDSNKPVEDANEPVEDTSEPVEDAGEPVQETNE</Hsp_hseq>
      <Hsp_midline>+ + +    P   + TP     +   N P    N PV   N  V   N PV   N PV   N PV   N PV   N  V   + PV     PV+  N </Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>3.38298e-07</Hsp_evalue>
      <Hsp_query-from>450</Hsp_query-from>
      <Hsp_query-to>680</Hsp_query-to>
      <Hsp_hit-from>470</Hsp_hit-from>
      <Hsp_hit-to>546</Hsp_hit-to>
      <Hsp_query-frame>-2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>30</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>77</Hsp_align-len>
      <Hsp_qseq>SVRTLNTPVRTLNTPVRTLNTSVITLNAPVVTLNTPVRTLNTPVRTLNTPVRTLNTSVITLNAPVVTLNTPVRTLNT</Hsp_qseq>
      <Hsp_hseq>SIEDANEPAEDSNEPVEDSNKPVKDSNKPVEDSNKPVEDSNKPVEDSNKPVEDANEPVEDTSEPVEDAGEPVQETNE</Hsp_hseq>
      <Hsp_midline>S+   N P    N PV   N  V   N PV   N PV   N PV   N PV   N  V   + PV     PV+  N </Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>4</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>4.04856e-06</Hsp_evalue>
      <Hsp_query-from>786</Hsp_query-from>
      <Hsp_query-to>1028</Hsp_query-to>
      <Hsp_hit-from>466</Hsp_hit-from>
      <Hsp_hit-to>546</Hsp_hit-to>
      <Hsp_query-frame>-2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>25</Hsp_identity>
      <Hsp_positive>31</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>81</Hsp_align-len>
      <Hsp_qseq>TLNTSVRTLNTPVRTLNTSIRTLNTSVRTLNTPVRTLNTPVRTLNTSVITLNALVVTLNTPVRTLNTPVRTLNTPVRTLNT</Hsp_qseq>
      <Hsp_hseq>EVNESIEDANEPAEDSNEPVEDSNKPVKDSNKPVEDSNKPVEDSNKPVEDSNKPVEDANEPVEDTSEPVEDAGEPVQETNE</Hsp_hseq>
      <Hsp_midline> +N S+   N P    N  +   N  V+  N PV   N PV   N  V   N  V   N PV   + PV     PV+  N </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1052050820</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

