<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0055560-RA transcript Note:&quot;Similar to TMEM170B Transmembrane protein 170B (Homo sapiens)&quot; offset:335 AED:0.00 eAED:0.00 QI:335|1|1|1|1|1|3|4345|127</BlastOutput_query-def>
  <BlastOutput_query-len>5064</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055560-RA transcript Note:&quot;Similar to TMEM170B Transmembrane protein 170B (Homo sapiens)&quot; offset:335 AED:0.00 eAED:0.00 QI:335|1|1|1|1|1|3|4345|127</Iteration_query-def>
  <Iteration_query-len>5064</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3541313195</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055561-RA transcript Note:&quot;Similar to MEAK7 MTOR-associated protein MEAK7 (Gallus gallus)&quot; offset:306 AED:0.36 eAED:0.44 QI:306|0.62|0.55|1|0.75|0.66|9|0|331</Iteration_query-def>
  <Iteration_query-len>1302</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>93</Statistics_hsp-len>
      <Statistics_eff-space>784391047</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055562-RA transcript Note:&quot;Similar to ca2 Carbonic anhydrase 2 (Tribolodon hakonensis)&quot; offset:0 AED:0.37 eAED:0.37 QI:0|0|0|0.8|0.75|0.6|5|0|211</Iteration_query-def>
  <Iteration_query-len>636</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>86</Statistics_hsp-len>
      <Statistics_eff-space>295654842</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0035569-RA transcript Note:&quot;Similar to CDH13 Cadherin-13 (Bos taurus)&quot; offset:2 AED:0.99 eAED:1.00 QI:2|0|0|0.16|0|0.16|6|35|314</Iteration_query-def>
  <Iteration_query-len>982</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>549855879</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055564-RA transcript Note:&quot;Similar to ECI2 Enoyl-CoA delta isomerase 2, mitochondrial (Homo sapiens)&quot; offset:0 AED:0.57 eAED:0.63 QI:0|0.25|0.44|0.77|1|1|9|0|527</Iteration_query-def>
  <Iteration_query-len>1584</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YLR284C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:706198:707040:-1 gene:YLR284C transcript:YLR284C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ECI1 description:Peroxisomal delta3,delta2-enoyl-CoA isomerase; hexameric protein that converts 3-hexenoyl-CoA to trans-2-hexenoyl-CoA, essential for the beta-oxidation of unsaturated fatty acids, oleate-induced; ECI1 has a paralog, DCI1, that arose from the whole genome duplication [Source:SGD;Acc:S000004274]</Hit_def>
  <Hit_accession>YLR284C</Hit_accession>
  <Hit_len>280</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>1.97711e-08</Hsp_evalue>
      <Hsp_query-from>1021</Hsp_query-from>
      <Hsp_query-to>1545</Hsp_query-to>
      <Hsp_hit-from>59</Hsp_hit-from>
      <Hsp_hit-to>243</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>189</Hsp_align-len>
      <Hsp_qseq>LKRAGDYFCSGNDLSNFTNILPSGIKQMALDAAELLRRFVS-------SFIEFPKPLVAVVNGPALGVAVTLLGL-------YDAATFQTPFSQLGQSPEGCSSYIFPKLMGAAKATEMLLFNKRLTSQQACDLGLVTEVYPDNSFQREVWARLETLAKLPKKREALHAANLRECQCLIECLQSEECMA</Hsp_qseq>
      <Hsp_hseq>IQSSGRFFSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFISKNFNMPSSNAEAF-NAKVLEELREKVKGLY---LPSCLGMKKLLKSNHIDA</Hsp_hseq>
      <Hsp_midline>++ +G +F SG D             +   + ++ +  FV+       +FI+  K L+  +NGPA+G++  L+ L        D      PF+ LG   EG ++   P   G     E L+FNK       C+ G +++ +   S   E +   + L +L +K + L+   L  C  + + L+S    A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>995451478</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055565-RA transcript Note:&quot;Similar to ECI2 Enoyl-CoA delta isomerase 2, mitochondrial (Homo sapiens)&quot; offset:122 AED:0.34 eAED:0.34 QI:122|0.42|0.5|1|1|1|8|0|303</Iteration_query-def>
  <Iteration_query-len>1034</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YLR284C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:706198:707040:-1 gene:YLR284C transcript:YLR284C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ECI1 description:Peroxisomal delta3,delta2-enoyl-CoA isomerase; hexameric protein that converts 3-hexenoyl-CoA to trans-2-hexenoyl-CoA, essential for the beta-oxidation of unsaturated fatty acids, oleate-induced; ECI1 has a paralog, DCI1, that arose from the whole genome duplication [Source:SGD;Acc:S000004274]</Hit_def>
  <Hit_accession>YLR284C</Hit_accession>
  <Hit_len>280</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>1.21644e-10</Hsp_evalue>
      <Hsp_query-from>453</Hsp_query-from>
      <Hsp_query-to>974</Hsp_query-to>
      <Hsp_hit-from>59</Hsp_hit-from>
      <Hsp_hit-to>259</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>201</Hsp_align-len>
      <Hsp_qseq>LKRAGDYFCSGNDLSNFTNIPPSGIKQMALDAADLLRRFVS-------SFIEFPKPLVAVVNGPAVGVSVTLLGL-------YDAATFHTPFSQLGQSPEGCSSYIFPKLMGAAKATEMLLFNKRLTSQQACDLGLVTEVY--PDNS---FQREVWARLETLAK---LP-----KKLSRDAEREALHAANLRECQRLIERW</Hsp_qseq>
      <Hsp_hseq>IQSSGRFFSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFNKANSVEVNESLKYW</Hsp_hseq>
      <Hsp_midline>++ +G +F SG D             +   + +  +  FV+       +FI+  K L+  +NGPA+G+S  L+ L        D      PF+ LG   EG ++   P   G     E L+FNK       C+ G +++ +  P ++   F  +V   L    K   LP     KKL +    +A + AN  E    ++ W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>589297018</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055566-RA transcript Note:&quot;Similar to Tubulin beta-1 chain (Manduca sexta)&quot; offset:109 AED:0.51 eAED:0.51 QI:109|1|0.66|1|1|1|3|0|109</Iteration_query-def>
  <Iteration_query-len>439</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YFL037W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:56336:57709:1 gene:YFL037W transcript:YFL037W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TUB2 description:Beta-tubulin; associates with alpha-tubulin (Tub1p and Tub3p) to form tubulin dimer, which polymerizes to form microtubules; mutation in human ortholog is associated with congenital fibrosis of the extraocular muscles (CFEOM) with polymicrogyria [Source:SGD;Acc:S000001857]</Hit_def>
  <Hit_accession>YFL037W</Hit_accession>
  <Hit_len>457</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>144.436</Hsp_bit-score>
      <Hsp_score>363</Hsp_score>
      <Hsp_evalue>1.39838e-42</Hsp_evalue>
      <Hsp_query-from>110</Hsp_query-from>
      <Hsp_query-to>391</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>94</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>94</Hsp_align-len>
      <Hsp_qseq>MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEASGGKFVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGR</Hsp_qseq>
      <Hsp_hseq>MREIIHISTGQCGNQIGAAFWETICGEHGLDFNGTYHGHDDIQKERLNVYFNEASSGKWVPRSINVDLEPGTIDAVRNSAIGNLFRPDNYIFGQ</Hsp_hseq>
      <Hsp_midline>MREI+HI  GQCGNQIGA FWE I  EHG+D  G+YHG  D+Q ER+NVY+NEAS GK+VPR+I VDLEPGT+D+VR+   G +FRPDN++FG+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YML085C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:97941:99400:-1 gene:YML085C transcript:YML085C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TUB1 description:Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules; relative distribution to nuclear foci increases upon DNA replication stress; TUB1 has a paralog, TUB3, that arose from the whole genome duplication [Source:SGD;Acc:S000004550]</Hit_def>
  <Hit_accession>YML085C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.4261</Hsp_bit-score>
      <Hsp_score>215</Hsp_score>
      <Hsp_evalue>1.3824e-21</Hsp_evalue>
      <Hsp_query-from>110</Hsp_query-from>
      <Hsp_query-to>394</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>98</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>100</Hsp_align-len>
      <Hsp_qseq>MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQL-----ERINVYYNEASGGKFVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGRQ</Hsp_qseq>
      <Hsp_hseq>MREVISINVGQAGCQIGNACWELYSLEHGIKPDG--HLEDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRNGPYKDLFHPEQLISGKE</Hsp_hseq>
      <Hsp_midline>MRE++ I  GQ G QIG   WE+ S EHGI P G  H +  L       E  + +++E   GKFVPRAI VDLEP  +D VR+GP+  +F P+  + G++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YML124C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:22048:23683:-1 gene:YML124C transcript:YML124C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TUB3 description:Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules; expressed at lower level than Tub1p; TUB3 has a paralog, TUB1, that arose from the whole genome duplication [Source:SGD;Acc:S000004593]</Hit_def>
  <Hit_accession>YML124C</Hit_accession>
  <Hit_len>445</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.1889</Hsp_bit-score>
      <Hsp_score>204</Hsp_score>
      <Hsp_evalue>4.96533e-20</Hsp_evalue>
      <Hsp_query-from>110</Hsp_query-from>
      <Hsp_query-to>394</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>98</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>100</Hsp_align-len>
      <Hsp_qseq>MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQL-----ERINVYYNEASGGKFVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGRQ</Hsp_qseq>
      <Hsp_hseq>MREVISINVGQAGCQIGNACWELYSLEHGIKEDG--HLEDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRTGRFKELFHPEQLINGKE</Hsp_hseq>
      <Hsp_midline>MRE++ I  GQ G QIG   WE+ S EHGI   G  H +  L       E  + +++E   GKFVPRAI VDLEP  +D VR+G F ++F P+  + G++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YLR212C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:564860:566281:-1 gene:YLR212C transcript:YLR212C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TUB4 description:Gamma-tubulin; involved in nucleating microtubules from both the cytoplasmic and nuclear faces of the spindle pole body; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004202]</Hit_def>
  <Hit_accession>YLR212C</Hit_accession>
  <Hit_len>473</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.5362</Hsp_bit-score>
      <Hsp_score>140</Hsp_score>
      <Hsp_evalue>1.9137e-11</Hsp_evalue>
      <Hsp_query-from>116</Hsp_query-from>
      <Hsp_query-to>376</Hsp_query-to>
      <Hsp_hit-from>4</Hsp_hit-from>
      <Hsp_hit-to>91</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>94</Hsp_align-len>
      <Hsp_qseq>EIVHIQAGQCGNQIGAKFWEVISDEHGID-------PTGSYHGDSDLQLERINVYYNEASGGKFVPRAILVDLEPGTMDSVRSGPFGQIFRPDN</Hsp_qseq>
      <Hsp_hseq>EIITLQAGQCGNHVGKFLWSQLAKEHAIGTDGLSQLPDSSTERDDDTK-----PFFRENSRNKFTPRAIMMDSEPSVIADVEN-TFRGFFDPRN</Hsp_hseq>
      <Hsp_midline>EI+ +QAGQCGN +G   W  ++ EH I        P  S   D D +      ++ E S  KF PRAI++D EP  +  V +  F   F P N</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>81</Statistics_hsp-len>
      <Statistics_eff-space>154665355</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055572-RA transcript Note:&quot;Similar to zc3h18 Zinc finger CCCH domain-containing protein 18 (Danio rerio)&quot; offset:100 AED:0.22 eAED:0.23 QI:100|0.23|0.35|0.57|0.92|0.92|14|2302|852</Iteration_query-def>
  <Iteration_query-len>4961</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3463113850</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055573-RA transcript Note:&quot;Similar to HAS3 Hyaluronan synthase 3 (Homo sapiens)&quot; offset:0 AED:0.05 eAED:0.05 QI:0|0|0|1|1|1|4|0|531</Iteration_query-def>
  <Iteration_query-len>1596</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YBR023C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:284428:287925:-1 gene:YBR023C transcript:YBR023C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHS3 description:Chitin synthase III; catalyzes the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for synthesis of the majority of cell wall chitin, the chitin ring during bud emergence, and spore wall chitosan; contains overlapping di-leucine and di-acidic signals that mediate, respectively, intracellular trafficking by AP-1 and trafficking to plasma membrane by exomer complex; requires AP-3 complex for its intracellular retention [Source:SGD;Acc:S000000227]</Hit_def>
  <Hit_accession>YBR023C</Hit_accession>
  <Hit_len>1165</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>1.16393e-07</Hsp_evalue>
      <Hsp_query-from>529</Hsp_query-from>
      <Hsp_query-to>1002</Hsp_query-to>
      <Hsp_hit-from>823</Hsp_hit-from>
      <Hsp_hit-to>999</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>178</Hsp_align-len>
      <Hsp_qseq>VLAESVDYIQVCDSDT-VLDSACTHELVRVLEADPCVGGVGGDVQILNRYASLLAFLSSVRYWVAFNVERACQSYFGCVQCISGPLGLYRSSLVREILEAWYG--------QRFLGSPCS---------FGDDRHLTNRVLGLGFSTK--YTARARCLTETPAGYLRWLNQQTRWSKS</Hsp_qseq>
      <Hsp_hseq>LMADFYETVLMVDADTKVFPDALTH-MVAEMVKDPLIMGLCGETKIANKAQSWVTAIQVFEYYISHHQAKAFESVFGSVTCLPGCFSMYRIKSPKGSDGYWVPVLANPDIVERYSDNVTNTLHKKNLLLLGEDRFLSSLMLKTFPKRKQVFVPKAACKTIAPDKFKVLLSQRRRWINS</Hsp_hseq>
      <Hsp_midline>++A+  + + + D+DT V   A TH +V  +  DP + G+ G+ +I N+  S +  +    Y+++ +  +A +S FG V C+ G   +YR    +     W          +R+  +  +          G+DR L++ +L      K  +  +A C T  P  +   L+Q+ RW  S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>1004626146</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055574-RA transcript Note:&quot;Similar to PDP1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial (Bos taurus)&quot; offset:0 AED:0.21 eAED:0.24 QI:0|0.37|0.55|1|0.75|0.66|9|1338|634</Iteration_query-def>
  <Iteration_query-len>3243</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YOR090C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:491123:492841:-1 gene:YOR090C transcript:YOR090C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTC5 description:Mitochondrial type 2C protein phosphatase (PP2C); involved in regulation of pyruvate dehydrogenase activity by dephosphorylating the serine 133 of the Pda1p subunit; localizes to the intermembrane space and is imported via the presequence pathway and processed by the inner membrane protease (Imp1p-Imp2p); acts in concert with kinases Pkp1p and Pkp2p and phosphatase Ptc6p [Source:SGD;Acc:S000005616]</Hit_def>
  <Hit_accession>YOR090C</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.8113</Hsp_bit-score>
      <Hsp_score>216</Hsp_score>
      <Hsp_evalue>2.79404e-18</Hsp_evalue>
      <Hsp_query-from>667</Hsp_query-from>
      <Hsp_query-to>1806</Hsp_query-to>
      <Hsp_hit-from>194</Hsp_hit-from>
      <Hsp_hit-to>540</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>109</Hsp_identity>
      <Hsp_positive>183</Hsp_positive>
      <Hsp_gaps>131</Hsp_gaps>
      <Hsp_align-len>429</Hsp_align-len>
      <Hsp_qseq>GVFDGHGGSTCAQAVSERLFGYVASALLPQHTXXXXXXXXXXXXXXXXXGGWALLSSELGQAQGQGLAYLPAPPELLRWHGPAPGGTARTHYSESLRTFWQELIDLDNGEGLGVRDALITAFKRLDSDISLEA-QVPWEHPSLARKARRT-AFSGCTACVAHVHGPD--LHVANVGDSRAVLGVRRADGSWSALSLTNDHSAQNEKEVARLRAEHPMKERKTVVXXXXXXXXXMPTRAFGDVRFKWSVELQRRVLDETGYAGRQLR--PQD----------------------EFVVLATDGLWEVMHRQE----VVRLVGEHLDRAPSRPAHQPLPRGRPLTLADMXXXXXXXXXXXXPTDGW--------------DRNPATLLVRHAV---GRGEWGGVEPDRLARMLALPEDMARLHRDDITLTV</Hsp_qseq>
      <Hsp_hseq>GIFDGHGGPFTSEKLSKDLVRYVAY--------------------------------QLGQVYDQNKTVFHSDP--------------------------NQLID----------SAISKGFLKLDNDLVIESFRKLFQDPNNTNIANTLPAISGSCALLSLYNSTNSILKVAVTGDSRALICGLDNEGNWTVKSLSTDQTGDNLDEVRRIRKEHPGEP--NVIRNGRILGSLQPSRAFGDYRYKIKEVDGKPLSDLPEVAKLYFRREPRDFKTPPYVTAEPVITSAKIGENTKFMVMGSDGLFELLTNEEIASLVIRWMDKNMNLAPVKAEPGKLPK-----VIDVSEDKEAQRPAFRYKDNNSSSPSGSNPEYLIEDKNVATHLIRNALSAGGRKEY-------VSALVSIPSPMSRRYRDDLTVTV</Hsp_hseq>
      <Hsp_midline>G+FDGHGG   ++ +S+ L  YVA                                 +LGQ   Q      + P                           +LID           A+   F +LD+D+ +E+ +  ++ P+    A    A SG  A ++  +  +  L VA  GDSRA++     +G+W+  SL+ D +  N  EV R+R EHP +    V+R GR+LG L P+RAFGD R+K      + + D    A    R  P+D                      +F+V+ +DGL+E++  +E    V+R + ++++ AP +     LP+     + D+    +A++ A    D                D+N AT L+R+A+   GR E+       ++ ++++P  M+R +RDD+T+TV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YDL006W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:439909:440754:1 gene:YDL006W transcript:YDL006W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTC1 description:Type 2C protein phosphatase (PP2C); dephosphorylates Hog1p, inactivating osmosensing MAPK cascade; involved in Fus3p activation during pheromone response; deletion affects precursor tRNA splicing, mitochondrial inheritance, and sporulation [Source:SGD;Acc:S000002164]</Hit_def>
  <Hit_accession>YDL006W</Hit_accession>
  <Hit_len>281</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>2.29216e-07</Hsp_evalue>
      <Hsp_query-from>1006</Hsp_query-from>
      <Hsp_query-to>1536</Hsp_query-to>
      <Hsp_hit-from>89</Hsp_hit-from>
      <Hsp_hit-to>250</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>194</Hsp_align-len>
      <Hsp_qseq>VRDALITAFKRLDSDISLEAQVPWEHPSLARKARRTAFSGCTA--CVAHVHGPD---------------LHVANVGDSRAVLGVRRADGSWSALSLTNDHSAQNEKEVARLRAEHPMKERKTVVXXXXXXXXXMPTRAFGDVRFKWSVELQRRVLDETGYAGRQLRPQDEFVVLATDGLWEVMHRQEVVRLVGE</Hsp_qseq>
      <Hsp_hseq>VRDVLNDSFLAIDEEIN---------------TKLVGNSGCTAAVCVLRWELPDSVSDDSMDLAQHQRKLYTANVGDSRIVL-FRNGN----SIRLTYDHKASDTLEMQRV------EQAGGLIMKSRVNGMLAVTRSLGDKFF------DSLVVGSPFTTSVEITSEDKFLILACDGLWDVIDDQDACELIKD</Hsp_hseq>
      <Hsp_midline>VRD L  +F  +D +I+                +    SGCTA  CV     PD               L+ ANVGDSR VL  R  +    ++ LT DH A +  E+ R+      ++   ++   R+ G+L  TR+ GD  F         V+        ++  +D+F++LA DGLW+V+  Q+   L+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YBL056W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:113762:115168:1 gene:YBL056W transcript:YBL056W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTC3 description:Type 2C protein phosphatase (PP2C); dephosphorylates Hog1p (see also Ptc2p) to limit maximal kinase activity induced by osmotic stress; dephosphorylates T169 phosphorylated Cdc28p (see also Ptc2p); role in DNA damage checkpoint inactivation; PTC3 has a paralog, PTC2, that arose from the whole genome duplication [Source:SGD;Acc:S000000152]</Hit_def>
  <Hit_accession>YBL056W</Hit_accession>
  <Hit_len>468</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>4.58512e-07</Hsp_evalue>
      <Hsp_query-from>1120</Hsp_query-from>
      <Hsp_query-to>1530</Hsp_query-to>
      <Hsp_hit-from>118</Hsp_hit-from>
      <Hsp_hit-to>249</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>143</Hsp_align-len>
      <Hsp_qseq>SGCTACVAHVHGPD--LHVANVGDSRAVLGVRRADGSWSALSLTNDHSAQNEKEVARLRAEHPMKERKTVVXXXXXXXXXMPTRAFGDVRFKWSVEL---QRRVLDETGYAGRQLR-PQDEFVVLATDGLWEVMHRQEVVRLV</Hsp_qseq>
      <Hsp_hseq>SGCTATVILVSQLKKLLICANSGDSRTVLSTG---GNSKAMSF--DHKPTLLSEKSRIVAADGFVEMDRV------NGNLALSRAIGDFEFKSNTKLGPHEQVVTCVPDIICHNLNYDEDEFVILACDGIWDCLTSQECVDLV</Hsp_hseq>
      <Hsp_midline>SGCTA V  V      L  AN GDSR VL      G+  A+S   DH      E +R+ A     E   V       G L  +RA GD  FK + +L   ++ V          L   +DEFV+LA DG+W+ +  QE V LV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2211239727</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055555-RA transcript Note:&quot;Similar to Snrpd1 Small nuclear ribonucleoprotein Sm D1 (Mus musculus)&quot; offset:813 AED:0.51 eAED:0.51 QI:813|0.2|0.33|0.66|0.4|0.5|6|0|532</Iteration_query-def>
  <Iteration_query-len>2412</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1600690502</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055556-RA transcript Note:&quot;Similar to sacm1lb Phosphatidylinositide phosphatase SAC1-B (Danio rerio)&quot; offset:0 AED:0.25 eAED:0.25 QI:0|0|0|0.88|0.75|0.77|9|0|309</Iteration_query-def>
  <Iteration_query-len>930</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YKL212W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:34543:36414:1 gene:YKL212W transcript:YKL212W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAC1 description:Phosphatidylinositol phosphate (PtdInsP) phosphatase; involved in hydrolysis of PtdIns[4]P in the early and medial Golgi; regulated by interaction with Vps74p; ER localized transmembrane protein which cycles through the Golgi; involved in protein trafficking and processing, secretion, and cell wall maintenance; regulates sphingolipid biosynthesis through the modulation of PtdIns(4)P metabolism [Source:SGD;Acc:S000001695]</Hit_def>
  <Hit_accession>YKL212W</Hit_accession>
  <Hit_len>623</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>147.517</Hsp_bit-score>
      <Hsp_score>371</Hsp_score>
      <Hsp_evalue>1.36377e-40</Hsp_evalue>
      <Hsp_query-from>58</Hsp_query-from>
      <Hsp_query-to>903</Hsp_query-to>
      <Hsp_hit-from>69</Hsp_hit-from>
      <Hsp_hit-to>356</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>96</Hsp_identity>
      <Hsp_positive>150</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>307</Hsp_align-len>
      <Hsp_qseq>YLIVVTKKEKQGEISGQAIWKAVEFDILSYQKTILHLTDLQAQDNKTLLMMLRGVLHTESFFFSCTFDLTHSLQRLANTSPDFHEMSLCERADQRFVWNGHLLRELLTV----PELHRFAVPLIHGFLSVKACVINGKVFDWILISRRSCYRAGVRYYLRGEARLLSFAESIDQEGHAANFVETEQIVFYGGNKA------SFVQGLAS---------------SVCISLPQLDGFQRHFDSQIVSYGKQIVVNLVDHKGSEKRLEEAFAALTKRLGSDWIQYEAFDFHKECSRMRWERLHILIDRL</Hsp_qseq>
      <Hsp_hseq>YAIIANTVEETGRFNGHVFYRVLQHSIVS-TKFNSRIDSEEAEYIKLLELHLK----NSTFYFSYTYDLTNSLQRNEKVGP----AASWKTADERFFWNHYLTEDLRNFAHQDPRIDSFIQPVIYGYAKTVDAVLNATPIVLGLITRRSIFRAGTRYFRRG----------VDKDGNVGNFNETEQILLAENPESEKIHVFSFLQTRGSVPIYWAEINNLKYKPNLVLGENSLDATKKHFDQQKELYGDNYLVNLVNQKGHELPVKEGYESVVHALNDPKIHYVYFDFHHECRKMQWHRVKLLIDHL</Hsp_hseq>
      <Hsp_midline>Y I+    E+ G  +G   ++ ++  I+S  K    +   +A+  K L + L+      +F+FS T+DLT+SLQR     P     +  + AD+RF WN +L  +L       P +  F  P+I+G+      V+N       LI+RRS +RAG RY+ RG          +D++G+  NF ETEQI+     ++      SF+Q   S               ++ +    LD  ++HFD Q   YG   +VNLV+ KG E  ++E + ++   L    I Y  FDFH EC +M+W R+ +LID L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YNL106C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:420944:424495:-1 gene:YNL106C transcript:YNL106C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:INP52 description:Polyphosphatidylinositol phosphatase; dephosphorylates a number of phosphatidylinositol phosphates (PtdInsPs, PIPs) to PI; involved in endocytosis; hyperosmotic stress causes translocation to actin patches; synaptojanin-like protein with a Sac1 domain; INP52 has a paralog, INP53, that arose from the whole genome duplication [Source:SGD;Acc:S000005050]</Hit_def>
  <Hit_accession>YNL106C</Hit_accession>
  <Hit_len>1183</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.0409</Hsp_bit-score>
      <Hsp_score>214</Hsp_score>
      <Hsp_evalue>2.06237e-19</Hsp_evalue>
      <Hsp_query-from>172</Hsp_query-from>
      <Hsp_query-to>864</Hsp_query-to>
      <Hsp_hit-from>154</Hsp_hit-from>
      <Hsp_hit-to>402</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>114</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>265</Hsp_align-len>
      <Hsp_qseq>DLQAQDNKTLLMMLRGVLHTESFFFSCTFDLTHSLQRLANTSPDFHEMSLC-ERADQRFVWNGHLLRELLT--------VPEL---HRFAVPLIHGFLSVKACVINGKVFDWILISRRSCYRAGVRYYLRGEARLLSFAESIDQEGHAANFVETEQIVFYGGNKASFVQGLAS-------SVCISLPQLD----------GFQRHFDSQIVSYGKQIVVNLVDHKGSEKRLEEAFAALTK-----RLGSDWIQYEAFDFHKECSR</Hsp_qseq>
      <Hsp_hseq>NAQEQAPKHPCHELRKLLSNGSFYYSTDFDLTCTLQKRG-----FTEHSLSFDDFDREFMWNSFLMDEIITYRDRLDVTAKELLDQRGFLTTVIRGFAETIFSYINRLKVGLTIISRQSWKRAGTRFNARG----------IDDDGHVANFVETEMIMYSSQYCYAFTQIRGSLPIFWEQDTSLISPKIQITRSVEATQPTFDEHFIRLFKKYGPVHIINLLSTKSSEIQLSRRYKEQLKNSEKMKIGRD-VFLTSFDFHRETSQ</Hsp_hseq>
      <Hsp_midline>+ Q Q  K     LR +L   SF++S  FDLT +LQ+       F E SL  +  D+ F+WN  L+ E++T          EL     F   +I GF       IN       +ISR+S  RAG R+  RG          ID +GH ANFVETE I++      +F Q   S          +  P++            F  HF      YG   ++NL+  K SE +L   +    K     ++G D +   +FDFH+E S+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YNL325C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:28739:31378:-1 gene:YNL325C transcript:YNL325C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FIG4 description:Phosphatidylinositol 3,5-bisphosphate (PtdIns[3,5]P) phosphatase; required for efficient mating and response to osmotic shock; physically associates with and regulated by Vac14p; contains a SAC1-like domain; homologous to human FIG4, which is associated with CMT4J, a form of Charcot-Marie-Tooth disorder [Source:SGD;Acc:S000005269]</Hit_def>
  <Hit_accession>YNL325C</Hit_accession>
  <Hit_len>879</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.7962</Hsp_bit-score>
      <Hsp_score>190</Hsp_score>
      <Hsp_evalue>2.50339e-16</Hsp_evalue>
      <Hsp_query-from>58</Hsp_query-from>
      <Hsp_query-to>609</Hsp_query-to>
      <Hsp_hit-from>117</Hsp_hit-from>
      <Hsp_hit-to>296</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>192</Hsp_align-len>
      <Hsp_qseq>YLIVVTKKEKQGEISGQAIWKAVEFDILSYQKTILHLTDLQAQDNKTLLMMLRGVLHTESFFFSCTFDLTHSLQ----RLANTSPDFHEMSL-CERAD--QRFVWNGHLLRELLT-VPELHRFAVPLIHGFLSVKACVINGKVFDWILISRRSCYRAGVRYYLRGEARLLSFAESIDQEGHAANFVETEQIV</Hsp_qseq>
      <Hsp_hseq>YLIMVTKYSQVAVIGGHGIYHIDGIDIIPITNN--YKKPEKSSDEARLLNIFKDLDLTKTFYFSYTYDITNTLQTNILREKLKAVDRCDITIPCGITDYNEMFVWNNNLLSPIFACIDTVFDWFQCIIHGFIDQVNVSVLGKSIYITLIARRSHHFAGARFLKRG----------VNNKGHVANEVETEQIV</Hsp_hseq>
      <Hsp_midline>YLI+VTK  +   I G  I+     DI+       +    ++ D   LL + + +  T++F+FS T+D+T++LQ    R    + D  ++++ C   D  + FVWN +LL  +   +  +  +   +IHGF+      + GK     LI+RRS + AG R+  RG          ++ +GH AN VETEQIV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YOR109W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:525278:528601:1 gene:YOR109W transcript:YOR109W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:INP53 description:Polyphosphatidylinositol phosphatase; dephosphorylates multiple phosphatidylinositol phosphates; involved in trans Golgi network-to-early endosome pathway; hyperosmotic stress causes translocation to actin patches; contains Sac1 and 5-ptase domains; INP53 has a paralog, INP52, that arose from the whole genome duplication [Source:SGD;Acc:S000005635]</Hit_def>
  <Hit_accession>YOR109W</Hit_accession>
  <Hit_len>1107</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.559</Hsp_bit-score>
      <Hsp_score>179</Hsp_score>
      <Hsp_evalue>6.08758e-15</Hsp_evalue>
      <Hsp_query-from>115</Hsp_query-from>
      <Hsp_query-to>894</Hsp_query-to>
      <Hsp_hit-from>109</Hsp_hit-from>
      <Hsp_hit-to>387</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>119</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>294</Hsp_align-len>
      <Hsp_qseq>WKAVEFDILSYQKTILHLTDLQAQD--NKTLLMMLRGVLHTESFFFSCTFDLTHSLQRLANTSPDFHEMSLCERADQRFVWNGHLLRELLT-----------VPELHRFAVPLIHGFLSVKACVINGKVFDWILISRRSCYRAGVRYYLRGEARLLSFAESIDQEGHAANFVETEQIVFYGGNKASFVQGLAS-------SVCISLPQLD----------GFQRHFDSQIVSYGKQIVVNLVDHKGSE----KRLEEAFAALTKRLGSDWIQYEAFDFHKECSRMRWERLHILI</Hsp_qseq>
      <Hsp_hseq>WDFIEIDSSGY-PVLPETASTEYQDALPKHPCYELKKLLSNGSFYYSSDFDLTSTLQHRGYGQ---HSLS-TDTYEEEYMWNSFLMQEMITYRDHLDTNLKQILDDEGFLTTVIRGFAETFVSYVKKLKVALTIISKQSWKRAGTRFNARG----------VDDEANVANFVETEFIMYSSQYCYAFTQIRGSIPVFWEQGTSLINPRVQITRSFEATQPVFDKHIMKSVEKYGPVHVVNLLSTKSSEIELSKRYKEHLTHSKKLNFNKDIFLTEFDFHKETSQEGFSGVRKLI</Hsp_hseq>
      <Hsp_midline>W  +E D   Y   +      + QD   K     L+ +L   SF++S  FDLT +LQ         H +S  +  ++ ++WN  L++E++T           + +   F   +I GF       +        +IS++S  RAG R+  RG          +D E + ANFVETE I++      +F Q   S          +  P++            F +H    +  YG   VVNL+  K SE    KR +E      K   +  I    FDFHKE S+  +  +  LI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>89</Statistics_hsp-len>
      <Statistics_eff-space>514193407</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055557-RA transcript Note:&quot;Similar to PDCD2L Programmed cell death protein 2-like (Gallus gallus)&quot; offset:363 AED:0.03 eAED:0.03 QI:363|0.85|0.87|1|0.85|0.75|8|423|386</Iteration_query-def>
  <Iteration_query-len>1947</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YOL022C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:280272:281498:-1 gene:YOL022C transcript:YOL022C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TSR4 description:Cytoplasmic protein required for correct processing of 20S pre-rRNA; protein required for processing of the 20S pre-rRNA at site D to generate mature 18S rRNA; essential gene in S288C background but not in CEN.PK2 [Source:SGD;Acc:S000005382]</Hit_def>
  <Hit_accession>YOL022C</Hit_accession>
  <Hit_len>408</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>2.43096e-11</Hsp_evalue>
      <Hsp_query-from>1174</Hsp_query-from>
      <Hsp_query-to>1494</Hsp_query-to>
      <Hsp_hit-from>294</Hsp_hit-from>
      <Hsp_hit-to>403</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>111</Hsp_align-len>
      <Hsp_qseq>GDRLFLKFMKRTARCPRQVLRYSWGGEPL-YVSAPDPHLTAPPTPCPLCGAPRVFEMQLMPALVWQLRGAEGTDSVPEFGSVLVFTCARSC---WAEAGGGVPCEEEVRFQ</Hsp_qseq>
      <Hsp_hseq>DDDTFQKFQEVVGYNPLQVLRYDLGGKPLLYAETKVDILSTVPRPGYNPSSQRIFEMQLMPKMIFDLEEVVSVDNGMEWGTILVFTDVENYMPEFDEHGVGY-VEECVKVQ</Hsp_hseq>
      <Hsp_midline> D  F KF +     P QVLRY  GG+PL Y       L+  P P     + R+FEMQLMP +++ L      D+  E+G++LVFT   +    + E G G   EE V+ Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1261098251</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055558-RA transcript Note:&quot;Similar to BCAR1 Breast cancer anti-estrogen resistance protein 1 (Homo sapiens)&quot; offset:0 AED:0.60 eAED:0.60 QI:0|0|0|0.16|1|1|6|0|823</Iteration_query-def>
  <Iteration_query-len>2472</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YHL002W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:102612:103970:1 gene:YHL002W transcript:YHL002W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSE1 description:Subunit of the endosomal Vps27p-Hse1p complex; complex is required for sorting of ubiquitinated membrane proteins into intralumenal vesicles prior to vacuolar degradation, as well as for recycling of Golgi proteins and formation of lumenal membranes [Source:SGD;Acc:S000000994]</Hit_def>
  <Hit_accession>YHL002W</Hit_accession>
  <Hit_len>452</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>1.10799e-08</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>174</Hsp_query-to>
      <Hsp_hit-from>223</Hsp_hit-from>
      <Hsp_hit-to>269</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>25</Hsp_identity>
      <Hsp_positive>32</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>50</Hsp_align-len>
      <Hsp_qseq>KALYDNVAESPDELAFRKGDIVTVLEQNAGGLQGWWLCSLHGRQGVAPGN</Hsp_qseq>
      <Hsp_hseq>RALYDLTTNEPDELSFRKGDVITVLEQ---VYRDWWKGALRGNMGIFPLN</Hsp_hseq>
      <Hsp_midline>+ALYD     PDEL+FRKGD++TVLEQ     + WW  +L G  G+ P N</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YHR016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:136881:138455:-1 gene:YHR016C transcript:YHR016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YSC84 description:Actin-binding protein; involved in bundling of actin filaments and endocytosis of actin cortical patches; activity stimulated by Las17p; contains SH3 domain similar to Rvs167p; YSC84 has a paralog, LSB3, that arose from the whole genome duplication [Source:SGD;Acc:S000001058]</Hit_def>
  <Hit_accession>YHR016C</Hit_accession>
  <Hit_len>468</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>3.59039e-07</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>186</Hsp_query-to>
      <Hsp_hit-from>414</Hsp_hit-from>
      <Hsp_hit-to>467</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>36</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>55</Hsp_align-len>
      <Hsp_qseq>AKALYDNVAESPDELAFRKGDIVTVLEQNAGGLQGWWLCSLHGRQGVAPGNRLRL</Hsp_qseq>
      <Hsp_hseq>AVALYNFAGEQPGDLAFKKGDVITILKK-SDSQNDWWTGRTNGKEGIFPANYVRV</Hsp_hseq>
      <Hsp_midline>A ALY+   E P +LAF+KGD++T+L++ +     WW    +G++G+ P N +R+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YFR024C-A</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:201960:203433:-1 gene:YFR024C-A transcript:YFR024C-A_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:LSB3 description:Protein containing a C-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization; protein abundance increases in response to DNA replication stress; LSB3 has a paralog, YSC84, that arose from the whole genome duplication [Source:SGD;Acc:S000002968]</Hit_def>
  <Hit_accession>YFR024C-A</Hit_accession>
  <Hit_len>459</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>4.46006e-06</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>189</Hsp_query-to>
      <Hsp_hit-from>405</Hsp_hit-from>
      <Hsp_hit-to>459</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>34</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>56</Hsp_align-len>
      <Hsp_qseq>AKALYDNVAESPDELAFRKGDIVTVLEQNAGGLQGWWLCSLHGRQGVAPGNRLRLL</Hsp_qseq>
      <Hsp_hseq>AVALYSFAGEESGDLPFRKGDVITILKK-SDSQNDWWTGRVNGREGIFPANYVELV</Hsp_hseq>
      <Hsp_midline>A ALY    E   +L FRKGD++T+L++ +     WW   ++GR+G+ P N + L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1646035842</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055559-RA transcript Note:&quot;Similar to Cfdp1 Craniofacial development protein 1 (Rattus norvegicus)&quot; offset:0 AED:0.65 eAED:0.71 QI:0|0.16|0|0.57|0.83|0.85|7|0|304</Iteration_query-def>
  <Iteration_query-len>915</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YBR231C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:682179:683090:-1 gene:YBR231C transcript:YBR231C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWC5 description:Component of the SWR1 complex; complex exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; protein abundance increases in response to DNA replication stress; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000000435]</Hit_def>
  <Hit_accession>YBR231C</Hit_accession>
  <Hit_len>303</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.3654</Hsp_bit-score>
      <Hsp_score>111</Hsp_score>
      <Hsp_evalue>9.70295e-07</Hsp_evalue>
      <Hsp_query-from>514</Hsp_query-from>
      <Hsp_query-to>858</Hsp_query-to>
      <Hsp_hit-from>151</Hsp_hit-from>
      <Hsp_hit-to>276</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>129</Hsp_align-len>
      <Hsp_qseq>KVSITKVFDFAGEEVRVTKEVDAESKEARSYLXXXX----------XXXXXXXXXXXXXXXXXXRPGGAAGLSAVLGQI--GGKKTKMSTLEKSKMDWDQFKEVEGISDELATHNRG--KAGWAFLDRV</Hsp_qseq>
      <Hsp_hseq>KILIERNYKFAGETVHEKKWVSRSSAEGQEYLNSLKFKQQAPAAPVQLEKAVRTKSNESRQHLRRPLKRPPL---LEQIISGGLRPKLTTLEKSQLDWASYVDRAGLNDELVLHNKDGFLARQEFLQRV</Hsp_hseq>
      <Hsp_midline>K+ I + + FAGE V   K V   S E + YL SL+            ++  + +  +     +RP     L   L QI  GG + K++TLEKS++DW  + +  G++DEL  HN+    A   FL RV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>89</Statistics_hsp-len>
      <Statistics_eff-space>502560072</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055563-RA transcript Note:&quot;Similar to Pskh1 Serine/threonine-protein kinase H1 (Mus musculus)&quot; offset:0 AED:0.03 eAED:0.03 QI:0|-1|0|1|-1|1|1|0|355</Iteration_query-def>
  <Iteration_query-len>1068</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>160.614</Hsp_bit-score>
      <Hsp_score>405</Hsp_score>
      <Hsp_evalue>8.34211e-46</Hsp_evalue>
      <Hsp_query-from>304</Hsp_query-from>
      <Hsp_query-to>951</Hsp_query-to>
      <Hsp_hit-from>53</Hsp_hit-from>
      <Hsp_hit-to>253</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>85</Hsp_identity>
      <Hsp_positive>125</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>220</Hsp_align-len>
      <Hsp_qseq>IGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGR----EACACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEET</Hsp_qseq>
      <Hsp_hseq>LGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLK------------------GEEDLIYKAAGSLGYVAPEVLTQDG-HGKPCDIWSIGVITYTLLCGYSPFIAES</Hsp_hseq>
      <Hsp_midline>+G GSF  V +A   S+ +  AIK++   A +G     +    EL++L+++ HPN+V   + FE+  + Y+V +LATGGELFDRIL+RG FTE DA   +  +L    Y+H+  + HRDLKPEN+LY     +S L I DFG+A  ++                  G E  +  A G+  Y+ PEVL++ G   +  D+W+IGVI+Y LL G  PF  E+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>156.762</Hsp_bit-score>
      <Hsp_score>395</Hsp_score>
      <Hsp_evalue>2.24178e-44</Hsp_evalue>
      <Hsp_query-from>283</Hsp_query-from>
      <Hsp_query-to>990</Hsp_query-to>
      <Hsp_hit-from>36</Hsp_hit-from>
      <Hsp_hit-to>256</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>86</Hsp_identity>
      <Hsp_positive>128</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>240</Hsp_align-len>
      <Hsp_qseq>KYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGR----EACACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGKY</Hsp_qseq>
      <Hsp_hseq>KYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSD------------------EELLYKPAGSLGYVAPEVLTQDG-HGKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEY</Hsp_hseq>
      <Hsp_midline>KY     +G G+F  V +A++  + +  A+K++   A +G     EA   EL +L+R+ HPN+V   + FE+  + Y++ +LA GGELFDRIL +G FTE DA R L  +L   +Y+H+  I HRDLKPENLLY     +S L + DFG+A  +++                   E  +    G+  Y+ PEVL++ G   +  D+W+IGVI+Y LL G   F  E           G+Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>145.591</Hsp_bit-score>
      <Hsp_score>366</Hsp_score>
      <Hsp_evalue>5.98009e-39</Hsp_evalue>
      <Hsp_query-from>292</Hsp_query-from>
      <Hsp_query-to>1026</Hsp_query-to>
      <Hsp_hit-from>200</Hsp_hit-from>
      <Hsp_hit-to>440</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>87</Hsp_identity>
      <Hsp_positive>144</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>264</Hsp_align-len>
      <Hsp_qseq>LKALIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGR-EACACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALS-MLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLF-ITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVL------------SRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGKYSYVGEVR----AEEAR</Hsp_qseq>
      <Hsp_hseq>IDEVVGQGAFATVKKAIERTTGKTFAVKIISKRKVIGNMDGVTRELEVLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGE-DAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQD--DPVLVKITDFGLA-------------------KVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSY-HEGPLKDFRISEEAR</Hsp_hseq>
      <Hsp_midline>+  ++G+G+F++V +A  R++ + +A+K++      G  +    EL VL+++ HP +V+L   +E     Y+VME  +GG+L D + A G+  E DA R +S  +L   +Y+H++GI+HRDLKP+N+L      D  L  ITDFGLA                      G  S ++T CGT  Y+ PEV+              R  ++  VDMW++G + Y++L+G +PF   T+ +L++ I RG Y + G ++    +EEAR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>133.265</Hsp_bit-score>
      <Hsp_score>334</Hsp_score>
      <Hsp_evalue>5.97511e-35</Hsp_evalue>
      <Hsp_query-from>265</Hsp_query-from>
      <Hsp_query-to>993</Hsp_query-to>
      <Hsp_hit-from>48</Hsp_hit-from>
      <Hsp_hit-to>270</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>84</Hsp_identity>
      <Hsp_positive>129</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>250</Hsp_align-len>
      <Hsp_qseq>DARVTAKYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVET-----SATEGREACACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLF--ITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGKYS</Hsp_qseq>
      <Hsp_hseq>DGAHIGNYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGR--IEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLL-----DEHLNVKIADFGLS-NIMT----------------DG--NFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYT</Hsp_hseq>
      <Hsp_midline>D      Y +   +G GSF  V  A H ++ Q  A+K++       S  +GR     E++ LR +RHP++++L +V ++     +V+E A G ELFD I+ R   +E++A R    ++    Y H   I HRDLKPENLL      D  L   I DFGL+ N+                  DG  + ++T+CG+P Y  PEV+S +      VD+W+ GVI Y++L   +PF++E+   LF+ I  G Y+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>130.568</Hsp_bit-score>
      <Hsp_score>327</Hsp_score>
      <Hsp_evalue>1.9937e-34</Hsp_evalue>
      <Hsp_query-from>235</Hsp_query-from>
      <Hsp_query-to>996</Hsp_query-to>
      <Hsp_hit-from>186</Hsp_hit-from>
      <Hsp_hit-to>441</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>88</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>52</Hsp_gaps>
      <Hsp_align-len>281</Hsp_align-len>
      <Hsp_qseq>RKVAKYR--AKFDARVTAKYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGREACAC---ELAVLRRVRHPNVVQLIEVFETPT-----RTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLL----------------YYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEET-RSRLFRAILRGKYSY</Hsp_qseq>
      <Hsp_hseq>RKLNKTRPVSFFD-----KYLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFT-------------------GEMQFTNTLCGTPSYVAPEVLTKKG-YTSKVDLWSAGVILYVCLCGFPPFSDQLGPPSLKEQILQAKYAF</Hsp_hseq>
      <Hsp_midline>RK+ K R  + FD     KY L   +G G ++ V  A+++ + Q  A+K+      + ++       E  +L RV+HPN+V L++ F  P      + YLV+E    GELF+RI+ +    + ++      LL G +YLH   I HRD+KPEN+L                +     D ++ I DFGLA                      G      T CGTP Y+ PEVL+++G +T  VD+W+ GVI Y+ L G  PF ++     L   IL+ KY++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>131.339</Hsp_bit-score>
      <Hsp_score>329</Hsp_score>
      <Hsp_evalue>5.3387e-34</Hsp_evalue>
      <Hsp_query-from>235</Hsp_query-from>
      <Hsp_query-to>1017</Hsp_query-to>
      <Hsp_hit-from>114</Hsp_hit-from>
      <Hsp_hit-to>341</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>263</Hsp_align-len>
      <Hsp_qseq>RKVAKYRAKFDARVTAKYDLKALIGRGSFSSVVRAEHRSSRQ--PYAIKLVETSATEGREACACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGKYSYVGEVRAE</Hsp_qseq>
      <Hsp_hseq>KKKAFVHCSNNGTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYGIER--------------EIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLL--DKKNRRIKIADFGMAA-------------------LELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMPSNLSSE</Hsp_hseq>
      <Hsp_midline>+K A      +  V   Y    +    S  S+   EH +  Q  PY I+               E+ +++ + H NV+ L EV+E  +  YLV+E   GGELFD ++++G   ER+A      ++EG  Y H+  I HRDLKPENLL      + R+ I DFG+A                     + P   ++T+CG+P Y  PE++  R       D+W+ G++ + LL+G +PF ++   +L   +  GKY     + +E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>126.716</Hsp_bit-score>
      <Hsp_score>317</Hsp_score>
      <Hsp_evalue>1.8965e-32</Hsp_evalue>
      <Hsp_query-from>286</Hsp_query-from>
      <Hsp_query-to>990</Hsp_query-to>
      <Hsp_hit-from>21</Hsp_hit-from>
      <Hsp_hit-to>246</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>79</Hsp_identity>
      <Hsp_positive>125</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>251</Hsp_align-len>
      <Hsp_qseq>YDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETS--ATEGREA---------CACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLL---YYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRS--RLFRAILRGKY</Hsp_qseq>
      <Hsp_hseq>WKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYN------IKIADFGMAA---------------LQTDAD----LLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQF</Hsp_hseq>
      <Hsp_midline>+ L   +G GS   V  A+H  +    A+K++  S     G  +            E+ +++ + HPNV+ L +V+ET    YL++E A  GELF+ ++  G   ER+A      ++ G  Y HALGI HRDLKPENLL   +Y+      + I DFG+A                 + + D     + T+CG+P Y  PE++S       A D+W+ GVI + LL+G +PF+EE  +   L   + +G++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>123.25</Hsp_bit-score>
      <Hsp_score>308</Hsp_score>
      <Hsp_evalue>2.35974e-31</Hsp_evalue>
      <Hsp_query-from>286</Hsp_query-from>
      <Hsp_query-to>981</Hsp_query-to>
      <Hsp_hit-from>347</Hsp_hit-from>
      <Hsp_hit-to>559</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>235</Hsp_align-len>
      <Hsp_qseq>YDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGREACACELA---VLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILR</Hsp_qseq>
      <Hsp_hseq>FDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQG---HIALCDFGLC--------------KLNMKDDDKTD----TFCGTPEYLAPELLLGLG-YTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQ</Hsp_hseq>
      <Hsp_midline>+DL  +IG+GSF  V++   + +++ YA+K +  S    +      LA   VL RV  P +V L   F++P + Y V+    GGELF  +   G F    A    + LL     LH L + +RDLKPEN+L  + G    + + DFGL               + + +++D  +    T CGTPEY+ PE+L   G +T+AVD W +GV+ Y +L+G  P+ +E   ++++ IL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>123.25</Hsp_bit-score>
      <Hsp_score>308</Hsp_score>
      <Hsp_evalue>2.78431e-31</Hsp_evalue>
      <Hsp_query-from>286</Hsp_query-from>
      <Hsp_query-to>948</Hsp_query-to>
      <Hsp_hit-from>19</Hsp_hit-from>
      <Hsp_hit-to>234</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>82</Hsp_identity>
      <Hsp_positive>118</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>238</Hsp_align-len>
      <Hsp_qseq>YDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVE-----TSATEGREACAC------------ELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEE</Hsp_qseq>
      <Hsp_hseq>WKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDH---KYNIKIADFGMAA----------------LETEG---KLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEE</Hsp_hseq>
      <Hsp_midline>+ L   +G GS   V  A + S+ Q  A+K++      T    G                  E+ +++ + HPNV++L +V+ET T  YLV+E A  GELF+ ++ RG   E +A R    ++ G  Y HALGI HRDLKPENLL  H      + I DFG+A                  E E      + T+CG+P Y  PE++S       A D+W+ GVI + LL+G +PF+EE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>119.398</Hsp_bit-score>
      <Hsp_score>298</Hsp_score>
      <Hsp_evalue>4.11401e-30</Hsp_evalue>
      <Hsp_query-from>286</Hsp_query-from>
      <Hsp_query-to>981</Hsp_query-to>
      <Hsp_hit-from>344</Hsp_hit-from>
      <Hsp_hit-to>556</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>122</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>235</Hsp_align-len>
      <Hsp_qseq>YDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGREACACELA---VLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILR</Hsp_qseq>
      <Hsp_hseq>FDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQG---HIALCDFGLC-------------KLNMKDNDK-----TDTFCGTPEYLAPEILLGQG-YTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQ</Hsp_hseq>
      <Hsp_midline>+DL  +IG+GSF  V++   + +++ YA+K +  +    +      LA   VL RV  P +V L   F++P + YLV+    GGELF  +   G F+   +   ++ LL     LH L + +RDLKPEN+L  + G    + + DFGL                  ++N+        T CGTPEY+ PE+L  +G +T+ VD W +G++ Y +++G  P+ +E    +++ IL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>118.242</Hsp_bit-score>
      <Hsp_score>295</Hsp_score>
      <Hsp_evalue>1.35285e-29</Hsp_evalue>
      <Hsp_query-from>286</Hsp_query-from>
      <Hsp_query-to>1029</Hsp_query-to>
      <Hsp_hit-from>412</Hsp_hit-from>
      <Hsp_hit-to>642</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>254</Hsp_align-len>
      <Hsp_qseq>YDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGREACACE------LAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGKYSYVGEVRAEEARS</Hsp_qseq>
      <Hsp_hseq>FEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILL---DANGNIALCDFGLS--------------------KADLKDRTNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRS</Hsp_hseq>
      <Hsp_midline>+++  L+G+G+F  V + + + +++ YA+K++       +   A        L        P +V L   F+TPT  YLV +  +GGELF  +   G F+E  A   ++ L+    +LH   I +RDLKPEN+L     A+  + + DFGL+                    +   +    T CGT EY+ PE+L     +T+ VD W++GV+ + +  G  PF  E   ++++ I  GK  +  +V ++E RS</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>115.931</Hsp_bit-score>
      <Hsp_score>289</Hsp_score>
      <Hsp_evalue>3.79755e-29</Hsp_evalue>
      <Hsp_query-from>283</Hsp_query-from>
      <Hsp_query-to>1002</Hsp_query-to>
      <Hsp_hit-from>120</Hsp_hit-from>
      <Hsp_hit-to>377</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>82</Hsp_identity>
      <Hsp_positive>124</Hsp_positive>
      <Hsp_gaps>62</Hsp_gaps>
      <Hsp_align-len>280</Hsp_align-len>
      <Hsp_qseq>KYDLKALIGRGSFSSVVRAE--HRSSRQPYAIKLVETSATEG--------------REACACELAVLRRV--RHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHP----GADSRLF------------------ITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGKYSYVG</Hsp_qseq>
      <Hsp_hseq>NYKLLNKIGEGAFSRVFKAVGINTDDQAPVAIKAIIKKGISSDAILKGNDRIQGSSRKKVLNEVAIHKLVSKNNPHCTKFIAFQESANYYYLVTELVTGGEIFDRIVQLTCFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLL-FEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLR--------------------NNTAKTPCGTIEYVASEVFTSK-RYSMKVDMWSIGCVLFTLLCGYPPFYEKNEKTLLKKISRGDYEFLA</Hsp_hseq>
      <Hsp_midline> Y L   IG G+FS V +A   +   + P AIK +                     R+    E+A+ + V   +P+  + I   E+    YLV EL TGGE+FDRI+    F+E  A   ++ +    +++H +GI HRD+KPENLL + P    G D  +                   + DFGLA  +R                     +  +T CGT EY+  EV + +  ++  VDMW+IG + + LL G  PF E+    L + I RG Y ++ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>113.235</Hsp_bit-score>
      <Hsp_score>282</Hsp_score>
      <Hsp_evalue>8.89225e-29</Hsp_evalue>
      <Hsp_query-from>304</Hsp_query-from>
      <Hsp_query-to>996</Hsp_query-to>
      <Hsp_hit-from>76</Hsp_hit-from>
      <Hsp_hit-to>284</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>236</Hsp_align-len>
      <Hsp_qseq>IGRGSFSSV--VRAEHRSSRQPYAIKLV---ETSATEGREACACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGKYSY</Hsp_qseq>
      <Hsp_hseq>LGTGSFGRVHLVRSVHNGRY--YAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILL---DRNGHIKITDFGFAKEV---------------------QTVTWTLCGTPDYIAPEVITTK-PYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVY</Hsp_hseq>
      <Hsp_midline>+G GSF  V  VR+ H      YAIK++   +    +  E    E  +L+ V HP ++++   F+     ++VM+   GGELF  +     F    A    + ++    YLHA  I +RDLKPEN+L      +  + ITDFG A  V                     ++   T CGTP+Y+ PEV++ +  + ++VD W++GV+ Y +L+G  PF + T  + +  IL+GK  Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>108.227</Hsp_bit-score>
      <Hsp_score>269</Hsp_score>
      <Hsp_evalue>3.21757e-26</Hsp_evalue>
      <Hsp_query-from>367</Hsp_query-from>
      <Hsp_query-to>948</Hsp_query-to>
      <Hsp_hit-from>78</Hsp_hit-from>
      <Hsp_hit-to>255</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>199</Hsp_align-len>
      <Hsp_qseq>AIKLV--ETSATEGREACAC--ELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPE-VLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEE</Hsp_qseq>
      <Hsp_hseq>AIKLIKRDSISNDYRKEVKIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLL---DKNENLVITDFGFVNEF-------------CSRNE-----LMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPWDDD</Hsp_hseq>
      <Hsp_midline>AIKL+  ++ + + R+      E+  L+ + HPN+V+L EV +      +V+E A GGE +  I  +    E +A R  S L+ G  Y+H+ G+ HRDLK ENLL      +  L ITDFG                     NE      ++T+CG+P Y  PE V+S      +  D+W+ GVI Y +L+G +P++++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>106.301</Hsp_bit-score>
      <Hsp_score>264</Hsp_score>
      <Hsp_evalue>1.30068e-25</Hsp_evalue>
      <Hsp_query-from>301</Hsp_query-from>
      <Hsp_query-to>978</Hsp_query-to>
      <Hsp_hit-from>329</Hsp_hit-from>
      <Hsp_hit-to>555</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>233</Hsp_align-len>
      <Hsp_qseq>LIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGREACA---CELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGS--FTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEEN--EDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAIL</Hsp_qseq>
      <Hsp_hseq>LLGQGDVGKVYLVRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSG---HVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRT--NSFVGTEEYLAPEVI-RGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNIL</Hsp_hseq>
      <Hsp_midline>L+G+G    V     R + Q +A+K++       R+       E  +L    HP +V L   F+T    YL ME   GGE F  +  R S    E DA    S ++    YLH LG  +RDLKPEN+L +  G    + ++DF L+      +          +     DG  +   +  GT EY+ PEV+ R    T AVD W +G++ Y +L G  PF+ +  +  F  IL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>106.301</Hsp_bit-score>
      <Hsp_score>264</Hsp_score>
      <Hsp_evalue>1.5235e-25</Hsp_evalue>
      <Hsp_query-from>286</Hsp_query-from>
      <Hsp_query-to>1029</Hsp_query-to>
      <Hsp_hit-from>11</Hsp_hit-from>
      <Hsp_hit-to>260</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>258</Hsp_align-len>
      <Hsp_qseq>YDLKALIGRGSFSSVVRA-EHRSSRQPYAIK------LVETSATEGREACACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQ---AVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGKYSYVGEVRAEEARS</Hsp_qseq>
      <Hsp_hseq>FIFKEELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLL---DRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCA-SFVGTAEYVSPELL----LYNQCGYGSDIWALGCMIYQFVQGQPPFRGENELKTFEKIVALDYPWGPNNRINNSTS</Hsp_hseq>
      <Hsp_midline>+  K  +G GS+S+V +A + +S  + YAIK      +++ +  +        + +L +  H  +++L   F      Y V++ A GGEL   +   G+F +       + L++   ++H+ GI HRDLKPEN+L      D RL ITDFG A  +         +           ++C  +  GT EY+ PE+L     + Q     D+WA+G + Y  + G  PF  E   + F  I+   Y +    R   + S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>103.99</Hsp_bit-score>
      <Hsp_score>258</Hsp_score>
      <Hsp_evalue>2.26882e-25</Hsp_evalue>
      <Hsp_query-from>268</Hsp_query-from>
      <Hsp_query-to>987</Hsp_query-to>
      <Hsp_hit-from>75</Hsp_hit-from>
      <Hsp_hit-to>298</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>249</Hsp_align-len>
      <Hsp_qseq>ARVTA-KYDLKAL-----IGRGSFSSVVRAEHRSSRQPYAIKLVETSAT---EGREACACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGK</Hsp_qseq>
      <Hsp_hseq>ARVTSGKYSLQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILL---DKNGHIKITDFGFAKYV---------------------PDVTYTLCGTPDYIAPEVVSTK-PYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAE</Hsp_hseq>
      <Hsp_midline>ARVT+ KY L+       +G GSF  V     R + + YA+K+++       +  E    E  +L  V HP ++++   F+   + +++M+   GGELF  +     F    A    + +     YLH+  I +RDLKPEN+L      +  + ITDFG A  V                          T CGTP+Y+ PEV+S +  + +++D W+ G++ Y +L+G  PF +    + +  IL  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>103.219</Hsp_bit-score>
      <Hsp_score>256</Hsp_score>
      <Hsp_evalue>2.31163e-25</Hsp_evalue>
      <Hsp_query-from>343</Hsp_query-from>
      <Hsp_query-to>975</Hsp_query-to>
      <Hsp_hit-from>123</Hsp_hit-from>
      <Hsp_hit-to>313</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>214</Hsp_align-len>
      <Hsp_qseq>HRSSRQPYAIKLVETSAT---EGREACACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAI</Hsp_qseq>
      <Hsp_hseq>HRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILI---GFNNVIKLTDFGWSI-------------------INPPENRRKTVCGTIDYLSPEMVESR-EYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRI</Hsp_hseq>
      <Hsp_midline>HRS+    A+K++E         ++    E+ +   + HPN+ +    F    R YL+ME    GE++  +   G F +  A+  +  +     Y+H   I HRD+KPEN+L    G ++ + +TDFG +                     + PE+  +T CGT +Y+ PE++  R  +   +D WA+GV+++ LL+G  PFEEE +   ++ I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>105.531</Hsp_bit-score>
      <Hsp_score>262</Hsp_score>
      <Hsp_evalue>2.36918e-25</Hsp_evalue>
      <Hsp_query-from>286</Hsp_query-from>
      <Hsp_query-to>948</Hsp_query-to>
      <Hsp_hit-from>46</Hsp_hit-from>
      <Hsp_hit-to>255</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>231</Hsp_align-len>
      <Hsp_qseq>YDLKALIGRGSFSSVVRAEHRSSR-----QPYAIKLV--ETSATEGREACAC--ELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPE-VLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEE</Hsp_qseq>
      <Hsp_hseq>YIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLL---DKHENLVITDFGFVNEF-------------FEDNE-----LMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLPWDDD</Hsp_hseq>
      <Hsp_midline>Y + + +G G F  V     ++S      +  AIKL+  +T   +  +      E+  L+ + HPN++ L EV +      +V+E  +GGE +  I  +    E  A R  + L+ G  Y+H  G+ HRDLK ENLL         L ITDFG                   E+NE      ++T+CG+P Y  PE V+S +    +  D+W+ GVI Y +L+G +P++++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>103.99</Hsp_bit-score>
      <Hsp_score>258</Hsp_score>
      <Hsp_evalue>9.84922e-25</Hsp_evalue>
      <Hsp_query-from>277</Hsp_query-from>
      <Hsp_query-to>990</Hsp_query-to>
      <Hsp_hit-from>22</Hsp_hit-from>
      <Hsp_hit-to>235</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>240</Hsp_align-len>
      <Hsp_qseq>TAKYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGREACACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGS--FTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGKY</Hsp_qseq>
      <Hsp_hseq>SVQYHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSL-RRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILL---SADNTVKLADFGVSTIVN---------------------SSALTLAGTLNWMAPEILGNRGASTLS-DIWSLGATVVEMLTKNPPYHNLTDANIYYAVENDTY</Hsp_hseq>
      <Hsp_midline>+ +Y LK +IGRGS+  V +A ++ + Q  AIK V     E       E+++L+ + H N+V+           Y+++E    G L  R+++R S   +E ++   ++  L G +YLH  G+ HRD+K  N+L     AD+ + + DFG++  V                      S   T  GT  +M PE+L  RGA T + D+W++G     +L+   P+   T + ++ A+    Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>103.219</Hsp_bit-score>
      <Hsp_score>256</Hsp_score>
      <Hsp_evalue>1.74283e-24</Hsp_evalue>
      <Hsp_query-from>301</Hsp_query-from>
      <Hsp_query-to>996</Hsp_query-to>
      <Hsp_hit-from>501</Hsp_hit-from>
      <Hsp_hit-to>736</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>242</Hsp_align-len>
      <Hsp_qseq>LIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGREACA---CELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGS--FTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESC-----VRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGKYSY</Hsp_qseq>
      <Hsp_hseq>LLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSG---HIMLSDFDLS--IQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVI-RGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKNEVSF</Hsp_hseq>
      <Hsp_midline>L+G+G    V     + + + YA+K++       R        E  +L    HP +V L   F++    YL ME   GGE F  +  R +    E DA    S +     YLH LG  +RDLKPEN+L +  G    + ++DF L+  ++A            +      + C       +  GT EY+ PEV+ R    T AVD W +G++ Y +L G  PF+ +  +  F  IL+ + S+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>102.449</Hsp_bit-score>
      <Hsp_score>254</Hsp_score>
      <Hsp_evalue>2.20271e-24</Hsp_evalue>
      <Hsp_query-from>286</Hsp_query-from>
      <Hsp_query-to>999</Hsp_query-to>
      <Hsp_hit-from>163</Hsp_hit-from>
      <Hsp_hit-to>440</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>125</Hsp_positive>
      <Hsp_gaps>82</Hsp_gaps>
      <Hsp_align-len>299</Hsp_align-len>
      <Hsp_qseq>YDLKALIGRGSFSSVVRA--EHRSSRQ-------PYAIKLV-------------------ETSATEGREACACELAVLRRVRH--PNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYY------------------HPGADSRLF-------------ITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGKYSYV</Hsp_qseq>
      <Hsp_hseq>YKLINKIGEGAFSKVFRAIPAKNSSNEFLTKNYKAVAIKVIKKADLSSINGDHRKKDKGKDSTKTSSRDQVLKEVALHKTVSAGCSQIVAFIDFQETDSYYYIIQELLTGGEIFGEIVRLTYFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKN--------------------TKTPCGTVGYTAPEVV-KDEHYSMKVDMWGIGCVLYTMLCGFPPFYDEKIDTLTEKISRGEYTFL</Hsp_hseq>
      <Hsp_midline>Y L   IG G+FS V RA     SS +         AIK++                   +++ T  R+    E+A+ + V      +V  I+  ET +  Y++ EL TGGE+F  I+    F+E  +   +  L    +++H+LG+ HRD+KPENLL+                      AD  +F             + DFGL+  + +                       +T CGT  Y  PEV+ +   ++  VDMW IG + Y +L G  PF +E    L   I RG+Y+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>100.523</Hsp_bit-score>
      <Hsp_score>249</Hsp_score>
      <Hsp_evalue>3.44877e-24</Hsp_evalue>
      <Hsp_query-from>235</Hsp_query-from>
      <Hsp_query-to>996</Hsp_query-to>
      <Hsp_hit-from>71</Hsp_hit-from>
      <Hsp_hit-to>302</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>259</Hsp_align-len>
      <Hsp_qseq>RKVAKYRAKFDARVTAKYDLKALIGRGSFSSV--VRAEHRSSRQPYAIKLVETSAT---EGREACACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGKYSY</Hsp_qseq>
      <Hsp_hseq>KPMLQYRDTSGKYSLSDFQILRTLGTGSFGRVHLIRSNHNGRF--YALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILL---DKNGHIKITDFGFAKYV---------------------PDVTYTLCGTPDYIAPEVVSTK-PYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKF</Hsp_hseq>
      <Hsp_midline>+ + +YR        + + +   +G GSF  V  +R+ H      YA+K ++       +  E    E  +L  V HP ++++   F+   + ++VM+   GGELF  +     F    A    + +     YLH+  I +RDLKPEN+L      +  + ITDFG A  V                          T CGTP+Y+ PEV+S +  + ++VD W+ GV+ Y +L+G  PF      + +  IL  +  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>101.293</Hsp_bit-score>
      <Hsp_score>251</Hsp_score>
      <Hsp_evalue>3.60334e-24</Hsp_evalue>
      <Hsp_query-from>301</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>167</Hsp_hit-from>
      <Hsp_hit-to>385</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>54</Hsp_gaps>
      <Hsp_align-len>243</Hsp_align-len>
      <Hsp_qseq>LIGRGSFSSVVRAEHRSSR--------QPYAIKLVETSATEGREACACELAVLRRVRHPNVVQLIEVF-ETPTRTYLVMELATGGELFDRILARG----SFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEV-----------------LSRRGAFTQAVDMWAIGVISYILLSGTMPF</Hsp_qseq>
      <Hsp_hseq>IVGNGTFGHVLITHNSKERDEDVCYHPENYAVKIIKLKPNKFDK----EARILLRLDHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLF-SYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKER------------------MHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRG-YDSKCDLWSLGVITHIMLTGISPF</Hsp_hseq>
      <Hsp_midline>++G G+F  V+   +   R        + YA+K+++    +  +    E  +L R+ HPN++++   F +     Y+  +L  GG+LF   LA+G    S +E ++   +  +L+   YLH   I HRDLK +N+L   P   +R+ + DFG+A ++ + +                    + T  GTPEY  PEV                 L +RG +    D+W++GVI++I+L+G  PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>100.908</Hsp_bit-score>
      <Hsp_score>250</Hsp_score>
      <Hsp_evalue>5.05381e-24</Hsp_evalue>
      <Hsp_query-from>445</Hsp_query-from>
      <Hsp_query-to>942</Hsp_query-to>
      <Hsp_hit-from>74</Hsp_hit-from>
      <Hsp_hit-to>223</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>168</Hsp_align-len>
      <Hsp_qseq>RHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHA-LGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVL-SRRGAFTQAVDMWAIGVISYILLSGTMPFE</Hsp_qseq>
      <Hsp_hseq>KHPNVLRLIDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENILLDKNG---NLKLADFGLASQFR---------------RKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQTPWE</Hsp_hseq>
      <Hsp_midline>+HPNV++LI+   +    ++++E+A GG+LFD+I          A      L+    YLH   G+AHRD+KPEN+L    G    L + DFGLA   R                +DG         G+P YM PEVL S  G +    D+W+IG++ ++LL+G  P+E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>100.523</Hsp_bit-score>
      <Hsp_score>249</Hsp_score>
      <Hsp_evalue>1.3384e-23</Hsp_evalue>
      <Hsp_query-from>259</Hsp_query-from>
      <Hsp_query-to>1017</Hsp_query-to>
      <Hsp_hit-from>90</Hsp_hit-from>
      <Hsp_hit-to>349</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>120</Hsp_positive>
      <Hsp_gaps>51</Hsp_gaps>
      <Hsp_align-len>282</Hsp_align-len>
      <Hsp_qseq>KFDARVTAKYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLV-------------------ETSATEGREACACELAVLRR----------VRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGKYSYVGEVRAE</Hsp_qseq>
      <Hsp_hseq>QFHRRSLGDWEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESEILERQKRLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSG---EIKIIDFGLS-------------------NIFDYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYPSHLSIE</Hsp_hseq>
      <Hsp_midline>+F  R    ++    +G GS   V   +HR +++   IK+V                   E+   E ++    E+A  +R          + HP++ +L E+       Y++ E  +GG+L D I+  GS  E  A +    +    +YLHA  I HRDLK EN++    G    + I DFGL+                   N       + T CG+  +  PE+L  +      VD+W+ G++ Y+L+ G +PF++E  S L   I +GK  Y   +  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>99.3673</Hsp_bit-score>
      <Hsp_score>246</Hsp_score>
      <Hsp_evalue>1.75919e-23</Hsp_evalue>
      <Hsp_query-from>301</Hsp_query-from>
      <Hsp_query-to>987</Hsp_query-to>
      <Hsp_hit-from>133</Hsp_hit-from>
      <Hsp_hit-to>378</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>120</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>260</Hsp_align-len>
      <Hsp_qseq>LIGRGSFSSVVRAEHRSSRQPYAIK-------LVETSATEGR----------------------EACACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESC--VRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGK</Hsp_qseq>
      <Hsp_hseq>VLGQGAYGKVLLVKDVNTSKLYAMKQLRKAEILISQTATDSKREDEDKNDGNNNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRG---HLVLTDFGLS----------KKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGK-AYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNK</Hsp_hseq>
      <Hsp_midline>++G+G++  V+  +  ++ + YA+K       L+  +AT+ +                      E    E ++L  + HPN+V+L   F   ++ YL+++   GGELF  +   G+  E   +   + +    R+LH  G+ +RDLKPEN L    G    L +TDFGL+          +        +E+ PE+   + +  GTPEY  PE+L  + A++Q  D +++G + Y +L G  P+       +   I + K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>98.9821</Hsp_bit-score>
      <Hsp_score>245</Hsp_score>
      <Hsp_evalue>4.26811e-23</Hsp_evalue>
      <Hsp_query-from>280</Hsp_query-from>
      <Hsp_query-to>1026</Hsp_query-to>
      <Hsp_hit-from>39</Hsp_hit-from>
      <Hsp_hit-to>261</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>114</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>249</Hsp_align-len>
      <Hsp_qseq>AKYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGREACACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGKYSYVGEVRAEEAR</Hsp_qseq>
      <Hsp_hseq>GNYKILKQIGEGSFGKVYLALHRPTHRKVCLK----TSDKNDPNIVREVFYHRQFDFPYITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSMHCVHRDLKLENILLDKNG---NAKLTDFGFT-------------------RECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDAKVIPDDAR</Hsp_hseq>
      <Hsp_midline>  Y +   IG GSF  V  A HR + +   +K    ++ +       E+   R+   P + +L EV  T ++ ++ +E   G EL+D +L+    +  +     + +     Y H++   HRDLK EN+L    G      +TDFG                      E   ++ + T CGT  YM PE++ RR      +D+W++GVI Y L++G +PF+++  ++    I+  +  Y  +V  ++AR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>98.2117</Hsp_bit-score>
      <Hsp_score>243</Hsp_score>
      <Hsp_evalue>6.54318e-23</Hsp_evalue>
      <Hsp_query-from>301</Hsp_query-from>
      <Hsp_query-to>996</Hsp_query-to>
      <Hsp_hit-from>87</Hsp_hit-from>
      <Hsp_hit-to>300</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>236</Hsp_align-len>
      <Hsp_qseq>LIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEG---REACACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVL-SRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGKYSY</Hsp_qseq>
      <Hsp_hseq>FLGEGGFARCFQIKDDSG-EIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFF---DSNYNLKIGDFGLAAVL-------------ANESERK-----YTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSF</Hsp_hseq>
      <Hsp_midline> +G G F+   + +  S  + +A K V  ++ +    R+    E+ + + + HPN+VQ I+ FE  +  Y+++E+   G L + +  R   TE +     + +    +Y+H+  + HRDLK  N+ +    ++  L I DFGLA  +               E+E        T CGTP Y+ PEVL  +    +  VD+W++GV+ Y LL G  PF+    + ++  I    +S+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>98.2117</Hsp_bit-score>
      <Hsp_score>243</Hsp_score>
      <Hsp_evalue>7.00604e-23</Hsp_evalue>
      <Hsp_query-from>259</Hsp_query-from>
      <Hsp_query-to>1017</Hsp_query-to>
      <Hsp_hit-from>111</Hsp_hit-from>
      <Hsp_hit-to>370</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>118</Hsp_positive>
      <Hsp_gaps>51</Hsp_gaps>
      <Hsp_align-len>282</Hsp_align-len>
      <Hsp_qseq>KFDARVTAKYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLV-------------------ETSATEGREACACELAVLRR----------VRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGKYSYVGEVRAE</Hsp_qseq>
      <Hsp_hseq>QFHRKSLGDWEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPPPKNEQDVLERQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMI---SDSSEIKIIDFGLS-------------------NIYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKIKQGKVEYPQHLSIE</Hsp_hseq>
      <Hsp_midline>+F  +    ++    +G GS   V  A+HR + +  A+K+V                   E    E ++    E++  +R          + HP++ +L E+       Y++ E  +GG+L D I+  GS  E  A +    +     YLHA  I HRDLK EN++       S + I DFGL+                   N       + T CG+  +  PE+L         VD+W+ GV+ ++L+ G +PF++E  S L   I +GK  Y   +  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.1301</Hsp_bit-score>
      <Hsp_score>235</Hsp_score>
      <Hsp_evalue>8.5637e-22</Hsp_evalue>
      <Hsp_query-from>214</Hsp_query-from>
      <Hsp_query-to>996</Hsp_query-to>
      <Hsp_hit-from>151</Hsp_hit-from>
      <Hsp_hit-to>408</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>133</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>270</Hsp_align-len>
      <Hsp_qseq>EYIDPSSRKVAKYRAKFDARVTAK----YDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETS---ATEGREACACELAVLRRVRH-PNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQ-AVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGKYSY</Hsp_qseq>
      <Hsp_hseq>EHDSSSQKPIAKESSKAQKNIIKKGIKDFKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILL---DGEMKIKLTDFGTAKLLNP-------TNNSVSKPEYDLSTRSKSFVGTAEYVSPELLN--DSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKVQYAF</Hsp_hseq>
      <Hsp_midline>E+   S + +AK  +K    +  K    +   ++IG G++S+V+ A    +++ YA K++        +  +  + E   L+++ + P+VV+L   F+  +  Y ++E A  G+    +   GS  E  A    + +++   YLH+ GI HRD+KPEN+L      + ++ +TDFG A  +               + E    +  ++  GT EY+ PE+L+   +FT    D+WA G I + +++G  PF+       F+ +++ +Y++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.1301</Hsp_bit-score>
      <Hsp_score>235</Hsp_score>
      <Hsp_evalue>8.79394e-22</Hsp_evalue>
      <Hsp_query-from>304</Hsp_query-from>
      <Hsp_query-to>987</Hsp_query-to>
      <Hsp_hit-from>30</Hsp_hit-from>
      <Hsp_hit-to>283</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>66</Hsp_gaps>
      <Hsp_align-len>274</Hsp_align-len>
      <Hsp_qseq>IGRGSFSSVVRAEHRSSR-QPYAIKLVETSATEGR---EACACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDA---------------------ARALSMLLEGA---RYLHALGIAHRDLKPENLLYYHPGA---DSRLF---------------ITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGK</Hsp_qseq>
      <Hsp_hseq>IGKGSFATVYRGHLTSDKSQHVAIKEVSRAKLKNKKLLENLEIEIAILKKIKHPHIVGLIDCERTSTDFYLIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNT-------------------SLAETLCGSPLYMAPEILNYQ-KYNAKADLWSVGTVVFEMCCGTPPFRASNHLELFKKIKRAN</Hsp_hseq>
      <Hsp_midline>IG+GSF++V R    S + Q  AIK V  +  + +   E    E+A+L++++HP++V LI+   T T  YL+ME    G+L   +  R    E                        A  LS L + A   ++L +  + HRD+KP+NLL   P     DS+ F               I DFG A  +                      S   T CG+P YM PE+L+ +  +    D+W++G + + +  GT PF       LF+ I R  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>94.7449</Hsp_bit-score>
      <Hsp_score>234</Hsp_score>
      <Hsp_evalue>1.06125e-21</Hsp_evalue>
      <Hsp_query-from>214</Hsp_query-from>
      <Hsp_query-to>1002</Hsp_query-to>
      <Hsp_hit-from>104</Hsp_hit-from>
      <Hsp_hit-to>358</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>126</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>273</Hsp_align-len>
      <Hsp_qseq>EYIDPSSRKVAKYRAKFDARVTAKYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETS----ATEGREACACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPE-----SCVRTACGTPEYMPPEVLSRRGAFTQA-VDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGKYSYVG</Hsp_qseq>
      <Hsp_hseq>DVVDPATGELTKHVVKMGIK---DFKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQKLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILL---DKNMKVKLTDFGTA----------KILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDN--YTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKIQYAFTA</Hsp_hseq>
      <Hsp_midline>+ +DP++ ++ K+  K   +    +     +G GS+SSVV A  R S + YA+K++         + +     +LA+ +      + +L   F+     Y ++E A  G+    I   GS  E  A    S +++    LH +GI HRD+KPEN+L      + ++ +TDFG A          +          DG       +  ++  GT EY+ PE+L+    +T +  D+WA G I Y +L+G  PF+       F+ +++ +Y++  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.9745</Hsp_bit-score>
      <Hsp_score>232</Hsp_score>
      <Hsp_evalue>1.39217e-21</Hsp_evalue>
      <Hsp_query-from>271</Hsp_query-from>
      <Hsp_query-to>981</Hsp_query-to>
      <Hsp_hit-from>45</Hsp_hit-from>
      <Hsp_hit-to>290</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>261</Hsp_align-len>
      <Hsp_qseq>RVTAKYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGREACAC-----------ELAVLRRVRHPNVVQLIEVFETP--TRTYLVMELATGG--------ELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRT-ACGTPEYMPPEVLSRRGAF--TQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILR</Hsp_qseq>
      <Hsp_hseq>QILNNFEILATLGNGQYGKVKLARDLGTGALVAIKIL--NRFEKRSGYSLQLKVENPRVNQEIEVMKRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGT---VKISDFGVAMSTATGSTNI----------QSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPFNANSGLELFDSIIN</Hsp_hseq>
      <Hsp_midline>++   +++ A +G G +  V  A    +    AIK++  +  E R   +            E+ V++R  H NVV+L E+   P  T+ YLV+E  + G        ++  + +     T + + + +  ++ G  YLH+ GI HRD+KP NLL    G    + I+DFG+A +   G  +           +   E  +++ A GTP +  PE+ S    +  + A+D+W++GV  Y LL G +PF   +   LF +I+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>94.3597</Hsp_bit-score>
      <Hsp_score>233</Hsp_score>
      <Hsp_evalue>1.50478e-21</Hsp_evalue>
      <Hsp_query-from>244</Hsp_query-from>
      <Hsp_query-to>978</Hsp_query-to>
      <Hsp_hit-from>807</Hsp_hit-from>
      <Hsp_hit-to>1037</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>254</Hsp_align-len>
      <Hsp_qseq>AKYRAKFDARVTAKYD---LKALIGRGSFSSVVRAEHRSSRQPYAIK------LVETSATEGREACACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAIL</Hsp_qseq>
      <Hsp_hseq>AKHKKRAAKRRKVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQRLSVRRAKFYAAEVLL-ALKYFHDNGVIYRDLKLENILLTPEG---HIKIADYGLC------------------KDEMWYGNRTSTFCGTPEFMAPEILKEQ-EYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAIL</Hsp_hseq>
      <Hsp_midline>AK++ +   R     D   L  ++G+G+F  V+ ++ +++ +  AIK      +++    E   A      +  + +HP +  L   F+T  R Y  ME   GG+L   +  +     R    A  +LL   +Y H  G+ +RDLK EN+L    G    + I D+GL                   ++E    +   T CGTPE+M PE+L  +  +T+AVD WA GV+ Y +L    PF  +    +F AIL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>92.0485</Hsp_bit-score>
      <Hsp_score>227</Hsp_score>
      <Hsp_evalue>7.27651e-21</Hsp_evalue>
      <Hsp_query-from>265</Hsp_query-from>
      <Hsp_query-to>975</Hsp_query-to>
      <Hsp_hit-from>613</Hsp_hit-from>
      <Hsp_hit-to>826</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>237</Hsp_align-len>
      <Hsp_qseq>DARVTAKYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGREACACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAI</Hsp_qseq>
      <Hsp_hseq>DGDPSTKYANLVKIGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKELIINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTD-VVTHCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEG---DIKLTDFGFCAQINELNLKRT------------------TMVGTPYWMAPEVVSRK-EYGPKVDIWSLGIMIIEMIEGEPPYLNETPLRALYLI</Hsp_hseq>
      <Hsp_midline>D   + KY     IG+G+   V  A    +    AIK +       +E    E+ V++  +HPN+V  I+ +      +++ME   GG L D ++     TE          L G  +LH+ G+ HRD+K +N+L    G    + +TDFG    +                          T  GTP +M PEV+SR+  +   VD+W++G++   ++ G  P+  ET  R    I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.1965</Hsp_bit-score>
      <Hsp_score>217</Hsp_score>
      <Hsp_evalue>2.72251e-20</Hsp_evalue>
      <Hsp_query-from>271</Hsp_query-from>
      <Hsp_query-to>906</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>194</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>217</Hsp_align-len>
      <Hsp_qseq>RVTAKYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETSA-TEGREACAC-ELAVLRRVRHPNVVQLIEVFETPTRTYLVME-LATGGELFDRILARGS--FTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVI</Hsp_qseq>
      <Hsp_hseq>KVNMEYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNVIELIDIFMAYDNLNLVLEFLPTDLEV---VIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLF---SPDGQIKVADFGLARAIPA------------------PHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVI</Hsp_hseq>
      <Hsp_midline>+V  +Y  +  +G G+++ V      S+ +  AIK ++TS   +G +  A  E+  L+ ++HPNV++LI++F       LV+E L T  E+   ++   S  FT  D    + M L G  + H   I HRDLKP NLL+     D ++ + DFGLA  + A                  P   + +   T  Y  PE+L     +T A+D+W++GVI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>89.3521</Hsp_bit-score>
      <Hsp_score>220</Hsp_score>
      <Hsp_evalue>5.31229e-20</Hsp_evalue>
      <Hsp_query-from>295</Hsp_query-from>
      <Hsp_query-to>927</Hsp_query-to>
      <Hsp_hit-from>319</Hsp_hit-from>
      <Hsp_hit-to>525</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>KALIGRGSF--------SSVVRAEHRSSRQPYAIKLVETSATEGREA----CACELAVLRRVRHPNVVQLIEVFETPTRTYL-VMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSG</Hsp_qseq>
      <Hsp_hseq>QEVLGKGAFGVVRICQKKNVSSQDGNKSEKLYAVKEFKRRTSESAEKYSKRLTSEFCISSSLHHTNIVTTLDLFQDAKGEYCEVMEYCAGGDLFTLVVAAGKLEYMEADCFFKQLIRGVVYMHEMGVCHRDLKPENLLLTHDGV---LKITDFGNSECFKMAWEKNIHLSGG--------------VCGSSPYIAPEEYIKEEFDPRPVDIWACGVIYMAMRTG</Hsp_hseq>
      <Hsp_midline>+ ++G+G+F         +V   +   S + YA+K  +   +E  E        E  +   + H N+V  +++F+     Y  VME   GG+LF  ++A G     +A      L+ G  Y+H +G+ HRDLKPENLL  H G    L ITDFG +   +           G               CG+  Y+ PE   +     + VD+WA GVI   + +G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.2705</Hsp_bit-score>
      <Hsp_score>212</Hsp_score>
      <Hsp_evalue>3.84127e-19</Hsp_evalue>
      <Hsp_query-from>286</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>18</Hsp_hit-from>
      <Hsp_hit-to>217</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>223</Hsp_align-len>
      <Hsp_qseq>YDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETS-ATEGREACACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGG---ELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVL-SRRGAFTQAVDMWAIGVISYILLSGTMPF</Hsp_qseq>
      <Hsp_hseq>YSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNG-LPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGM---VKLGDFGVSGHIRSTLKRD-------------------TFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPPL</Hsp_hseq>
      <Hsp_midline>Y +++ IGRG+F  V +A  R +++  AIK+V    + E  E  A E+  L  ++ P +   I         ++VME   GG   +L  R    G   E   +  +  +  G +YLH     HRD+K  N+L    G    + + DFG++G++R+                        T  GTP +M PEV+      + +  D+W++G+ +Y LL G  P </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YMR291W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:852630:854390:1 gene:YMR291W transcript:YMR291W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TDA1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000004905]</Hit_def>
  <Hit_accession>YMR291W</Hit_accession>
  <Hit_len>586</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.1889</Hsp_bit-score>
      <Hsp_score>204</Hsp_score>
      <Hsp_evalue>5.05812e-18</Hsp_evalue>
      <Hsp_query-from>304</Hsp_query-from>
      <Hsp_query-to>1047</Hsp_query-to>
      <Hsp_hit-from>45</Hsp_hit-from>
      <Hsp_hit-to>326</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>118</Hsp_positive>
      <Hsp_gaps>72</Hsp_gaps>
      <Hsp_align-len>301</Hsp_align-len>
      <Hsp_qseq>IGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGR-EACACELAVLRRVR-------------------HPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFT-ERDAARALSMLLEGARYLHALGIAHRDLKPENLLY-------------YHPG------ADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGA-------------FTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGKYSYVGEVRAEEARSEGVEWG</Hsp_qseq>
      <Hsp_hseq>LGDGNFSVVKECMNIHTKDLYAMKLIKKQTVKNKIQLIQREFDLLRSISEKIRDMEKKNEHSLDIFEGHHHILQLFDYFETADNIVLITQLCQKGDLYEKIVENQCLDLETQVTSYCACLVSVLEFLHSQGIVHRDLKAENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLVLADFGLAA-----------------EYNTSKVNSLKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGCPVDIWALGVLTYFMAFGYTPFDCTTDDETLECISKCDY-YVDEQMMHDPKYEQF-WN</Hsp_hseq>
      <Hsp_midline>+G G+FS V    +  ++  YA+KL++    + + +    E  +LR +                    H +++QL + FET     L+ +L   G+L+++I+       E       + L+    +LH+ GI HRDLK EN+L+              H G          L + DFGLA                  E      + ++   GT  Y+ PE++  +G              +   VD+WA+GV++Y +  G  PF+  T       I +  Y YV E    + + E   W </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.1889</Hsp_bit-score>
      <Hsp_score>204</Hsp_score>
      <Hsp_evalue>6.95048e-18</Hsp_evalue>
      <Hsp_query-from>367</Hsp_query-from>
      <Hsp_query-to>948</Hsp_query-to>
      <Hsp_hit-from>592</Hsp_hit-from>
      <Hsp_hit-to>771</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>202</Hsp_align-len>
      <Hsp_qseq>AIKLVETSATEGREACACELAVLRRVRHPNVVQLIEVF-ETPTRTYLVMELATGGELFDRI-------LARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEE</Hsp_qseq>
      <Hsp_hseq>AIKQMVLSKQPRKELIVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLL---DTRARVKITDFGFCARLTDK------------------RSKRATMVGTPYWMAPEVVKQR-EYDEKIDVWSLGIMTIEMLEGEPPYLNE</Hsp_hseq>
      <Hsp_midline>AIK +  S    +E    E+ V++  RH N+V  +E +  T    ++VME   GG L D I        +    TE   A  +    +G ++LH   I HRD+K +N+L       +R+ ITDFG    +                      S   T  GTP +M PEV+ +R  + + +D+W++G+++  +L G  P+  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.4185</Hsp_bit-score>
      <Hsp_score>202</Hsp_score>
      <Hsp_evalue>1.23768e-17</Hsp_evalue>
      <Hsp_query-from>271</Hsp_query-from>
      <Hsp_query-to>978</Hsp_query-to>
      <Hsp_hit-from>128</Hsp_hit-from>
      <Hsp_hit-to>392</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>119</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>271</Hsp_align-len>
      <Hsp_qseq>RVTAKYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVE--------------TSATEGREACACELAVLRRVRHPNVVQLIEVFE--TPTRTYLVMELATGGEL------FDRILARG----SFTE-RDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFG--LAGNVRAXXXXXXXXXXXXEENEDG------PESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAIL</Hsp_qseq>
      <Hsp_hseq>KVLNTYEIIKELGHGQHGKVKLARDILSKQLVAIKIVDRHEKKQRKFFTFIKSSKISENDKIKREIAIMKKCHHKHVVQLIEVLDDLKSRKIYLVLEYCSRGEVKWCPPDCMESDAKGPSLLSFQETREILRGVVLGLE---YLHYQGIIHRDIKPANLLI---SGDGTVKISDFGVSLAASSTNSSDSSESLDELELAKTVGTPAFFAPEMCLGEDAFTRYNLTKENLFRGSCISFMIDIWAVGVTLYCLLFGMLPFFSDFELKLFEKIV</Hsp_hseq>
      <Hsp_midline>+V   Y++   +G G    V  A    S+Q  AIK+V+              +S     +    E+A++++  H +VVQLIEV +     + YLV+E  + GE+           A+G    SF E R+  R + + LE   YLH  GI HRD+KP NLL      D  + I+DFG  LA +        +           G      PE C+     T   +  E L R    +  +D+WA+GV  Y LL G +PF  +   +LF  I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.4185</Hsp_bit-score>
      <Hsp_score>202</Hsp_score>
      <Hsp_evalue>1.63572e-17</Hsp_evalue>
      <Hsp_query-from>301</Hsp_query-from>
      <Hsp_query-to>969</Hsp_query-to>
      <Hsp_hit-from>1180</Hsp_hit-from>
      <Hsp_hit-to>1391</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>233</Hsp_align-len>
      <Hsp_qseq>LIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGR--------EACACELAVLRRVRHPNVVQLIEVFETPTRTY-LVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEE-ETRSRLFR</Hsp_qseq>
      <Hsp_hseq>MIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLG-FENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICK---ISDFGIS-----------------RKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFK</Hsp_hseq>
      <Hsp_midline>+IG+GSF +V    + ++ +  A+K VE      +        EA   E++ L+ + H N+VQ +  FE     Y L +E   GG +   I   G F E       + +L+G  YLH+ GI HRD+K +NLL    G      I+DFG++                  +++D   +   T  GT  +M PE++  +  ++  VD+W++G I   + +G  P+   E  + +F+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.7221</Hsp_bit-score>
      <Hsp_score>195</Hsp_score>
      <Hsp_evalue>1.0352e-16</Hsp_evalue>
      <Hsp_query-from>274</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>1030</Hsp_hit-from>
      <Hsp_hit-to>1252</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>230</Hsp_align-len>
      <Hsp_qseq>VTAKYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGREAC----ACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSM-LLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPES-CVRTACGTPEYMPPEVLSRRGAFTQ--AVDMWAIGVISYILLSGTMPF</Hsp_qseq>
      <Hsp_hseq>VSMRWQKRSFIGGGTFGQVYSAINLENGEILAVKEIKIHDTTTMKKIFPLIKEEMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEYCEGGSLAS-LLDHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDFNGI---IKYVDFGTA---RTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPW</Hsp_hseq>
      <Hsp_midline>V+ ++  ++ IG G+F  V  A +  + +  A+K ++   T   +        E+ VL  + HPN+VQ   V     +  + ME   GG L   +L  G   +    +  +  LLEG  YLH  G+ HRD+KPEN+L    G    +   DFG A   R   G      R     + G E+  +    GTP YM PE +S      +  A D+WA+G +   + +G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YOR267C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:822588:824867:-1 gene:YOR267C transcript:YOR267C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRK1 description:Protein kinase; implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005793]</Hit_def>
  <Hit_accession>YOR267C</Hit_accession>
  <Hit_len>759</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.9518</Hsp_bit-score>
      <Hsp_score>193</Hsp_score>
      <Hsp_evalue>1.45063e-16</Hsp_evalue>
      <Hsp_query-from>388</Hsp_query-from>
      <Hsp_query-to>1020</Hsp_query-to>
      <Hsp_hit-from>254</Hsp_hit-from>
      <Hsp_hit-to>452</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>218</Hsp_align-len>
      <Hsp_qseq>SATEGREACACELAVLRRVRHPNVVQLIEVFETPTRT--YLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFT-QAVDMWAIGVISYILLSGTMPF----EEETRSRLFRAILRGKYSYVGEVRAEE</Hsp_qseq>
      <Hsp_hseq>SVKEYAKKCTAEFCIGSTLHHPNVIETVDVFSDSKQNKYYEVMEYCPID--FFAVVMTGKMSRGEINCCLKQLTEGVKYLHSMGLAHRDLKLDNCVMTSQGI---LKLIDFGSAVVFRYPF-------------EDG-VTMAHGIVGSDPYLAPEVITSTKSYDPQCVDIWSIGIIYCCMVLKRFPWKAPRDSDDNFRLYCMPDDIEHDYVESARHHE</Hsp_hseq>
      <Hsp_midline>S  E  + C  E  +   + HPNV++ ++VF    +   Y VME       F  ++  G  +  +    L  L EG +YLH++G+AHRDLK +N +    G    L + DFG A   R                EDG  +      G+  Y+ PEV++   ++  Q VD+W+IG+I   ++    P+    + +   RL+      ++ YV   R  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.0258</Hsp_bit-score>
      <Hsp_score>188</Hsp_score>
      <Hsp_evalue>2.6472e-16</Hsp_evalue>
      <Hsp_query-from>271</Hsp_query-from>
      <Hsp_query-to>906</Hsp_query-to>
      <Hsp_hit-from>8</Hsp_hit-from>
      <Hsp_hit-to>212</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>218</Hsp_align-len>
      <Hsp_qseq>RVTAKYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGREACAC-ELAVLRRVRHPNVVQLIEV-----FETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVI</Hsp_qseq>
      <Hsp_hseq>NISSDFQLKSLLGEGAYGVVCSATHKPTGEIVAIKKIEPFDKPLFALRTLREIKILKHFKHENIITIFNIQRPDSFENFNEVYIIQELMQTD--LHRVISTQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLI---NSNCDLKVCDFGLARII--------DESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCI</Hsp_hseq>
      <Hsp_midline> +++ + LK+L+G G++  V  A H+ + +  AIK +E             E+ +L+  +H N++ +  +     FE     Y++ EL        R+++    ++      +   L   + LH   + HRDLKP NLL     ++  L + DFGLA  +         +         G +S +     T  Y  PEV+     +++A+D+W+ G I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.0258</Hsp_bit-score>
      <Hsp_score>188</Hsp_score>
      <Hsp_evalue>8.87755e-16</Hsp_evalue>
      <Hsp_query-from>268</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>1260</Hsp_hit-from>
      <Hsp_hit-to>1500</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>249</Hsp_align-len>
      <Hsp_qseq>ARVTAKYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGREAC----ACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSM-LLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGP----------------ESCVRTACGTPEYMPPEVLSRRGAFTQ----AVDMWAIGVISYILLSGTMPF</Hsp_qseq>
      <Hsp_hseq>SNVSMRWQKRNFIGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSL-AALLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGV---IKYVDFGAAKKIANNGTRLASMNKI--ENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESIT--GSTTKGKLGADDVWSLGCVVLEMITGRRPW</Hsp_hseq>
      <Hsp_midline>+ V+ ++  +  IG G+F  V  A    + +  A+K +    ++  +        E++VL  + HPN+V    V     +  + ME   GG L   +L  G   +    +  ++ LLEG  YLH  GI HRD+KPEN+L    G    +   DFG A  +           +   EN DG                 E+ +    GTP YM PE ++  G+ T+    A D+W++G +   +++G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.2554</Hsp_bit-score>
      <Hsp_score>186</Hsp_score>
      <Hsp_evalue>1.11988e-15</Hsp_evalue>
      <Hsp_query-from>343</Hsp_query-from>
      <Hsp_query-to>948</Hsp_query-to>
      <Hsp_hit-from>396</Hsp_hit-from>
      <Hsp_hit-to>585</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>212</Hsp_align-len>
      <Hsp_qseq>HRSSRQPYAIKLVETSATEGREACACELAVLRRVRHPNVVQLIEVFETPTR-TYLVMELATGGELFDRI--LARGS-------FTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEE</Hsp_qseq>
      <Hsp_hseq>HRVVGERVAIKQIRLSEQPKKQLIMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGL---VKITDFGFCVELTEKRSKRA------------------TMVGTPYWMAPEIVNQKG-YDEKVDVWSLGIMLIEMIEGEPPYLNE</Hsp_hseq>
      <Hsp_midline>HR   +  AIK +  S    ++    EL V+   R  N+V  +E +       +++ME   GG L D +  +AR +         E   A  +    +G ++LH   I HRD+K +N+L    G    + ITDFG    +   +                      T  GTP +M PE+++++G + + VD+W++G++   ++ G  P+  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YPR111W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:747306:749000:1 gene:YPR111W transcript:YPR111W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF20 description:Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006315]</Hit_def>
  <Hit_accession>YPR111W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.8702</Hsp_bit-score>
      <Hsp_score>185</Hsp_score>
      <Hsp_evalue>1.42526e-15</Hsp_evalue>
      <Hsp_query-from>304</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>175</Hsp_hit-from>
      <Hsp_hit-to>407</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>239</Hsp_align-len>
      <Hsp_qseq>IGRGSFSSVVRAEHRSSRQPYAIKLVETS---ATEGREACACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAAR-ALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGL-AGNVRAXXXXXXXXXXXXEENEDGPESCVR---------------------TACGTPEYMPPEVLS-RRGAFTQAVDMWAIGVISYILLSGTMPF</Hsp_qseq>
      <Hsp_hseq>VGQGGYGQVYLAKKKDSDEICALKILNKKLLFKLNETNHVLTERDILTTTRSDWLVKLLYAFQDPESLYLAMEFVPGGD-FRTLLINTRILKSGHARFYISEMFCAVNALHELGYTHRDLKPENFLI---DATGHIKLTDFGLAAGTVSNERIESMKIRLEEVKNLEFPAFTERSIEDRRKIYHNMRKTEINYANSMVGSPDYMALEVLEGKKYDFT--VDYWSLGCMLFESLVGYTPF</Hsp_hseq>
      <Hsp_midline>+G+G +  V  A+ + S +  A+K++                E  +L   R   +V+L+  F+ P   YL ME   GG+ F  +L      +   AR  +S +      LH LG  HRDLKPEN L     A   + +TDFGL AG V   +           +N + P    R                     +  G+P+YM  EVL  ++  FT  VD W++G + +  L G  PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.0998</Hsp_bit-score>
      <Hsp_score>183</Hsp_score>
      <Hsp_evalue>2.2037e-15</Hsp_evalue>
      <Hsp_query-from>274</Hsp_query-from>
      <Hsp_query-to>975</Hsp_query-to>
      <Hsp_hit-from>19</Hsp_hit-from>
      <Hsp_hit-to>229</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>237</Hsp_align-len>
      <Hsp_qseq>VTAKYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGREACAC--ELAVLRRVRHPNVVQLIEVFETPTR-TYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAI</Hsp_qseq>
      <Hsp_hseq>ITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLSPLEDIYFVTELQ--GTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILI---NENCDLKICDFGLA-------------------RIQDPQ--MTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSII</Hsp_hseq>
      <Hsp_midline>+T +Y+    +G G+F  V  A    + QP AIK +    +    A     EL +L+ +RH N++ L ++F +P    Y V EL   G    R+L      ++     L  +L G +Y+H+ G+ HRDLKP N+L      +  L I DFGLA                       P+  +     T  Y  PE++     +   VD+W+ G I   ++ G   F  +     F  I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.7146</Hsp_bit-score>
      <Hsp_score>182</Hsp_score>
      <Hsp_evalue>3.36405e-15</Hsp_evalue>
      <Hsp_query-from>298</Hsp_query-from>
      <Hsp_query-to>948</Hsp_query-to>
      <Hsp_hit-from>218</Hsp_hit-from>
      <Hsp_hit-to>418</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>225</Hsp_align-len>
      <Hsp_qseq>ALIGRGSFSSVVRAEHRSSRQPYAIKLVETSAT--EGREACACELAVLRRVRHPNVVQLIEVF--ETPTRTYLVMELATGGEL---FDRILARGS-FTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEE</Hsp_qseq>
      <Hsp_hseq>GILGEGAGGSVAKCRLKNGKKVFALKTINTMNTDPEYQKQIFRELQFNKSFKSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKG---EIKLCDFGVSG--------------------EAVNSLAMTFTGTSFYMAPERIQGQ-PYSVTCDVWSLGLTLLEVAGGRFPFESD</Hsp_hseq>
      <Hsp_midline> ++G G+  SV +   ++ ++ +A+K + T  T  E ++    EL   +  +   +VQ   +F  E  +  Y+ ME   G  L   +  +L RG   +ER   +    +L G  YLH   + HRD+KP+N+L    G    + + DFG++G                    +   S   T  GT  YM PE +  +  ++   D+W++G+    +  G  PFE +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.0998</Hsp_bit-score>
      <Hsp_score>183</Hsp_score>
      <Hsp_evalue>3.50581e-15</Hsp_evalue>
      <Hsp_query-from>256</Hsp_query-from>
      <Hsp_query-to>987</Hsp_query-to>
      <Hsp_hit-from>13</Hsp_hit-from>
      <Hsp_hit-to>236</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>246</Hsp_align-len>
      <Hsp_qseq>AKFDARVTAKYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVE-TSATEGREACACELAVLRRVRH-PNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGK</Hsp_qseq>
      <Hsp_hseq>AEGEMDVSSLFKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSL-RSLLRPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEG---NVKLCDFGVAAQVNQTSLRR------------------QTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIKSK</Hsp_hseq>
      <Hsp_midline>A+ +  V++ +    +IGRG F  V +  +  + + YAIK++   S ++  E    E+  L  ++   N+ +    +   T  +++ME   GG L   +L  G   E+     +  LL   + +H   + HRD+K  N+L  + G    + + DFG+A  V                         +T  GTP +M PEV+     +   VD+W++G+ +Y + +G  P+ +    R  + I++ K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.3294</Hsp_bit-score>
      <Hsp_score>181</Hsp_score>
      <Hsp_evalue>6.84528e-15</Hsp_evalue>
      <Hsp_query-from>304</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>1102</Hsp_hit-from>
      <Hsp_hit-to>1304</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>230</Hsp_align-len>
      <Hsp_qseq>IGRGSFSSVVRAEHRSSRQPYAIK-------LVETSATEGREACACE----LAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGE-----LFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLF--ITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPF</Hsp_qseq>
      <Hsp_hseq>MGEGAYGKVNLCIHKKNRYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKKPHENILRLLDFFEDDD--YYYIETPVHGETGCIDLFDLIEFKTNMTEFEAKLIFKQVVAGIKHLHDQGIVHRDIKDENVI-----VDSKGFVKIIDFGSAAYVKS-----------------GP---FDVFVGTIDYAAPEVLGGNPYEGQPQDIWAIGILLYTVVFKENPF</Hsp_hseq>
      <Hsp_midline>+G G++  V    H+ +R    IK       LV+T   + +          +A L +  H N+++L++ FE     Y  +E    GE     LFD I  + + TE +A      ++ G ++LH  GI HRD+K EN++      DS+ F  I DFG A  V++                 GP        GT +Y  PEVL       Q  D+WAIG++ Y ++    PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>1.07534e-14</Hsp_evalue>
      <Hsp_query-from>304</Hsp_query-from>
      <Hsp_query-to>927</Hsp_query-to>
      <Hsp_hit-from>13</Hsp_hit-from>
      <Hsp_hit-to>205</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>218</Hsp_align-len>
      <Hsp_qseq>IGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGREACAC-ELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSM---------LLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSG</Hsp_qseq>
      <Hsp_hseq>LGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDN----DLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRG---QLKLGDFGLA---RAFGI---------------PVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITG</Hsp_hseq>
      <Hsp_midline>+G G++++V +  ++++    A+K V+  + EG  + A  E+++++ ++H N+V+L +V  T  +  LV E        D      S T  +  R L +         LL+G  + H   I HRDLKP+NLL    G   +L + DFGLA   RA                  P +   +   T  Y  P+VL     ++ ++D+W+ G I   +++G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>1.35375e-14</Hsp_evalue>
      <Hsp_query-from>445</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>143</Hsp_hit-from>
      <Hsp_hit-to>289</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>174</Hsp_align-len>
      <Hsp_qseq>RHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTE-RDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLS-------RRGAFTQA-VDMWAIGVISYILLSGTMPF</Hsp_qseq>
      <Hsp_hseq>RHQNIAALLDFFDS----YIIMEYCSGGDLYEAIKADAVPKKTKSITHIITQIMDAIEYVHNKGIYHRDIKPENILI--SGIDWTIKLTDWGLATTDK---------------------TSMDRNVGSERYMSPELFDSNLDIKERKEPYDCAKVDLWAMGIVFLNIVFHKNPF</Hsp_hseq>
      <Hsp_midline>RH N+  L++ F++    Y++ME  +GG+L++ I A     + +     ++ +++   Y+H  GI HRD+KPEN+L    G D  + +TD+GLA   +                     + +    G+  YM PE+         R+  +  A VD+WA+G++   ++    PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.8626</Hsp_bit-score>
      <Hsp_score>172</Hsp_score>
      <Hsp_evalue>5.50705e-14</Hsp_evalue>
      <Hsp_query-from>286</Hsp_query-from>
      <Hsp_query-to>987</Hsp_query-to>
      <Hsp_hit-from>177</Hsp_hit-from>
      <Hsp_hit-to>431</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>260</Hsp_align-len>
      <Hsp_qseq>YDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETS---ATEGREACACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAG----NVRAXXXXXXXXXXXXEENEDGPESCV------------------RTACGTPEYMPPEVLS-RRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGK</Hsp_qseq>
      <Hsp_hseq>FEMITQVGQGGYGQVYLARKKDTKEVCALKILNKKLLFKLNETKHVLTERDILTTTRSEWLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINTRCLKSGHARFYISEMFCAVNALHDLGYTHRDLKPENFLI---DAKGHIKLTDFGLAAGTISNERIESMKIRLEKIKDLEFPAFTEKSIEDRRKMYNQLREKEINYANSMVGSPDYMALEVLEGKKYDFT--VDYWSLGCMLFESLVGYTPFSGSSTNETYDNLRRWK</Hsp_hseq>
      <Hsp_midline>+++   +G+G +  V  A  + +++  A+K++           +    E  +L   R   +V+L+  F+     YL ME   GG+    ++         A   +S +      LH LG  HRDLKPEN L     A   + +TDFGLA     N R      + +     E     E  +                   +  G+P+YM  EVL  ++  FT  VD W++G + +  L G  PF   + +  +  + R K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>1.3744e-13</Hsp_evalue>
      <Hsp_query-from>445</Hsp_query-from>
      <Hsp_query-to>921</Hsp_query-to>
      <Hsp_hit-from>767</Hsp_hit-from>
      <Hsp_hit-to>919</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>161</Hsp_align-len>
      <Hsp_qseq>RHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAA-RALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSR-LFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILL</Hsp_qseq>
      <Hsp_hseq>RRRNFVKPMTAVKKKSTLFIQMEYCENRTLYDLIHSENLNQQRDEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI----DESRNVKIGDFGLAKNVH----RSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVLDGTGHYNEKIDMYSLGIIFFEMI</Hsp_hseq>
      <Hsp_midline>R  N V+ +   +  +  ++ ME      L+D I +     +RD   R    +LE   Y+H+ GI HRDLKP N+       +SR + I DFGLA NV           +   +N  G    + +A GT  Y+  EVL   G + + +DM+++G+I + ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.5514</Hsp_bit-score>
      <Hsp_score>166</Hsp_score>
      <Hsp_evalue>4.03424e-13</Hsp_evalue>
      <Hsp_query-from>304</Hsp_query-from>
      <Hsp_query-to>975</Hsp_query-to>
      <Hsp_hit-from>366</Hsp_hit-from>
      <Hsp_hit-to>576</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>233</Hsp_align-len>
      <Hsp_qseq>IGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGR-EACACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGEL---FDRILARGSFTERDAARALSMLLEGARYL-HALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSR----RGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAI</Hsp_qseq>
      <Hsp_hseq>LGHGNYGNVSKVLHKPTNVIMATKEVRLELDEAKFRQILMELEVLHKCNSPYIVDFYGAFFIEGAVYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCS--ANQGTVKLCDFGVSGNLVA--------------------SLAKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYPPETYDNIFSQL</Hsp_hseq>
      <Hsp_midline>+G G++ +V +  H+ +    A K V     E +      EL VL +   P +V     F      Y+ ME   GG L   +D     G   E   A   + ++ G + L     I HRD+KP N+L         + + DFG++GN+ A                    S  +T  G   YM PE +      R  +T   D+W++G+    +  G  P+  ET   +F  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YFL033C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:69115:74427:-1 gene:YFL033C transcript:YFL033C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM15 description:Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase [Source:SGD;Acc:S000001861]</Hit_def>
  <Hit_accession>YFL033C</Hit_accession>
  <Hit_len>1770</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>1.32762e-12</Hsp_evalue>
      <Hsp_query-from>286</Hsp_query-from>
      <Hsp_query-to>735</Hsp_query-to>
      <Hsp_hit-from>794</Hsp_hit-from>
      <Hsp_hit-to>946</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>156</Hsp_align-len>
      <Hsp_qseq>YDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETS---ATEGREACACELAVLR-RVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGL--AGNVR</Hsp_qseq>
      <Hsp_hseq>YDILKPISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDKPYVARLFASFQNKDNLFLVMEYLPGGDLATLIKMMGYLPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLIDNAG---HVKLTDFGLSRAGLIR</Hsp_hseq>
      <Hsp_midline>YD+   I +G++ SV  A  + +   +AIK++  S   A         E A++  +   P V +L   F+     +LVME   GG+L   I   G   ++ A + L+ ++ G   +H  GI H DLKPENLL  + G    + +TDFGL  AG +R</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>1.81174e-07</Hsp_evalue>
      <Hsp_query-from>820</Hsp_query-from>
      <Hsp_query-to>984</Hsp_query-to>
      <Hsp_hit-from>1149</Hsp_hit-from>
      <Hsp_hit-to>1203</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>22</Hsp_identity>
      <Hsp_positive>32</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>55</Hsp_align-len>
      <Hsp_qseq>GTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRG</Hsp_qseq>
      <Hsp_hseq>GTPDYLAPETIEGKGEDNKQCDWWSVGCIFFELLLGYPPFHAETPDAVFKKILSG</Hsp_hseq>
      <Hsp_midline>GTP+Y+ PE +  +G   +  D W++G I + LL G  PF  ET   +F+ IL G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>2.47348e-12</Hsp_evalue>
      <Hsp_query-from>271</Hsp_query-from>
      <Hsp_query-to>981</Hsp_query-to>
      <Hsp_hit-from>178</Hsp_hit-from>
      <Hsp_hit-to>395</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>243</Hsp_align-len>
      <Hsp_qseq>RVTAKYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETSAT-EGREACAC-ELAVLRRVRHPNVVQLIEVF-ETPTRTYLVMELATG---GELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILR</Hsp_qseq>
      <Hsp_hseq>RSTSVYLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNVSTIKEIMVESQKTVYMIFEYADNDLSGLLLNKEVQ---ISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQG---NLKITDFGLARKMNSRA--------------DYTNRVI-----TLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFK</Hsp_hseq>
      <Hsp_midline>R T+ Y     +G G++  V +A++ ++ +  A+K +      EG    +  E+ +L+   HPNV  + E+  E+    Y++ E A     G L ++ +     +          LL G  YLH   I HRD+K  N+L  + G    L ITDFGLA  + +                D     +     T  Y PPE+L     +   VDMW  G +   L + T  F+         +I +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YKL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:347214:349136:-1 gene:YKL048C transcript:YKL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ELM1 description:Serine/threonine protein kinase; regulates the orientation checkpoint, the morphogenesis checkpoint and the metabolic switch from fermentative to oxidative metabolism by phosphorylating the activation loop of Kin4p, Hsl1p and Snf4p respectively; cooperates with Hsl7p in recruiting Hsl1p to the septin ring, a prerequisite for subsequent recruitment, phosphorylation, and degradation of Swe1p; forms part of the bud neck ring; regulates cytokinesis [Source:SGD;Acc:S000001531]</Hit_def>
  <Hit_accession>YKL048C</Hit_accession>
  <Hit_len>640</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>3.79618e-12</Hsp_evalue>
      <Hsp_query-from>406</Hsp_query-from>
      <Hsp_query-to>993</Hsp_query-to>
      <Hsp_hit-from>163</Hsp_hit-from>
      <Hsp_hit-to>376</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>222</Hsp_align-len>
      <Hsp_qseq>EACACELAVLRRVRHP-NVVQLIEVFETP--TRTYLVMELATGGEL-------------FDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVL----SRRGAFTQA--VDMWAIGVISYILLSGTMPF----EEETRSRLFRAILRGKYS</Hsp_qseq>
      <Hsp_hseq>EKCRWEIFAASRLRNNVHIVRLIECLDSPFSESIWIVTNWCSLGELQWKRDDDEDILPQWKKIVISNCSVSTFAKKILEDMTKGLEYLHSQGCIHRDIKPSNILLDEEEKVAKL--SDFG------SCIFTPQSLPFSDANFEDCFQRELNKIVGTPAFIAPELCHLGNSKRDFVTDGFKLDIWSLGVTLYCLLYNELPFFGENEFETYHKIIEVSLSSKIN</Hsp_hseq>
      <Hsp_midline>E C  E+    R+R+  ++V+LIE  ++P     ++V    + GEL             + +I+         A + L  + +G  YLH+ G  HRD+KP N+L       ++L  +DFG      +     Q         ED  +  +    GTP ++ PE+     S+R   T    +D+W++GV  Y LL   +PF    E ET  ++    L  K +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>4.62073e-12</Hsp_evalue>
      <Hsp_query-from>304</Hsp_query-from>
      <Hsp_query-to>942</Hsp_query-to>
      <Hsp_hit-from>198</Hsp_hit-from>
      <Hsp_hit-to>446</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>74</Hsp_gaps>
      <Hsp_align-len>268</Hsp_align-len>
      <Hsp_qseq>IGRGSFSSVVRAEHRSSRQP-----------YAIKL--VETSATEGR---------EACACELAVLRRVRHPNVVQLI----EVFETPTRTY---------------LVMELATGGELFDRILAR-GSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLF-------------ITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFE</Hsp_qseq>
      <Hsp_hseq>IGSGNFSTVLLYELMDQSNPKLKQVAVKRLKYPEELSNVEQINTSLRYKETLSRLENSLTRELQVLKSLNHPCIVKLLGINNPIFVTSKKPLCDLIIKTPRALPPCDMIMSYCPAGDLLAAVMARNGRLEAWLIQRIFTEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLCKKI--------------ENNE-----MCTARCGSEDYVSPEILMGVPYDGHLSDTWALGVILYSLFEDRLPFD</Hsp_hseq>
      <Hsp_midline>IG G+FS+V+  E      P           Y  +L  VE   T  R          +   EL VL+ + HP +V+L+     +F T  +                 ++M     G+L   ++AR G        R  + ++   +YLH   I HRDLK EN+L  +   D   F             + DFGL   +              E NE          CG+ +Y+ PE+L          D WA+GVI Y L    +PF+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>6.40969e-12</Hsp_evalue>
      <Hsp_query-from>265</Hsp_query-from>
      <Hsp_query-to>942</Hsp_query-to>
      <Hsp_hit-from>16</Hsp_hit-from>
      <Hsp_hit-to>234</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>238</Hsp_align-len>
      <Hsp_qseq>DARVTAKYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGREACAC-----ELAVLRRVR-HPNVVQLIE---VFETP---TRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFE</Hsp_qseq>
      <Hsp_hseq>DFILNKHFHLTGKIGRGSHSLICSSTYTESNEETHVAIRKIPNAFGNKL-SCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLYEELMEC-DLSQIIRSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLV---NSDCQLKICNFGLSCSY--------------SENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFE</Hsp_hseq>
      <Hsp_midline>D  +   + L   IGRGS S +  + +  S +   + + +     G +  +C     EL +LR +R HPN+V L +   VF         YL  EL    +L   I +     +      +  +L   +Y+H+  + H DLKP+NLL     +D +L I +FGL+ +                EN    +  ++    +  Y  PE+L      T+AVD+W+ G I   LL     FE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>9.26627e-12</Hsp_evalue>
      <Hsp_query-from>268</Hsp_query-from>
      <Hsp_query-to>948</Hsp_query-to>
      <Hsp_hit-from>215</Hsp_hit-from>
      <Hsp_hit-to>425</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>235</Hsp_align-len>
      <Hsp_qseq>ARVTAKYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETSAT--EGREACACELAVLRRVRHPNVVQLIEVF--ETPTRTYLVMELATGGEL---FDRILARGS-FTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEE</Hsp_qseq>
      <Hsp_hseq>ANLKDRIETLGILGEGAGGSVSKCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQFNRSFQSEYIVRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENG---QVKLCDFGVSG--------------------EAVNSLATTFTGTSFYMAPERIQGQ-PYSVTSDVWSLGLTILEVANGKFPCSSE</Hsp_hseq>
      <Hsp_midline>A +  + +   ++G G+  SV + + ++  + +A+K++ T  T  E ++    EL   R  +   +V+   +F  +  +  Y+ ME   G  L   +  +L RG   +E+   +    +L G  YLH   + HRD+KP+N+L    G   ++ + DFG++G                    +   S   T  GT  YM PE +  +  ++   D+W++G+    + +G  P   E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>1.26252e-11</Hsp_evalue>
      <Hsp_query-from>301</Hsp_query-from>
      <Hsp_query-to>723</Hsp_query-to>
      <Hsp_hit-from>357</Hsp_hit-from>
      <Hsp_hit-to>497</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>146</Hsp_align-len>
      <Hsp_qseq>LIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGREACA---CELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSR--LFITDFGLA</Hsp_qseq>
      <Hsp_hseq>VIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNIL-----IDIRGHIKLSDFGLS</Hsp_hseq>
      <Hsp_midline>+IG+G+F  V   + + + + YA+K +  S    ++  A    E  VL     P VV L   F+     YL+ME   GG+L   ++    FTE      ++  +     +H LG  HRD+KP+N+L      D R  + ++DFGL+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>45.8246</Hsp_bit-score>
      <Hsp_score>107</Hsp_score>
      <Hsp_evalue>7.39696e-06</Hsp_evalue>
      <Hsp_query-from>811</Hsp_query-from>
      <Hsp_query-to>981</Hsp_query-to>
      <Hsp_hit-from>570</Hsp_hit-from>
      <Hsp_hit-to>625</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>31</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>57</Hsp_align-len>
      <Hsp_qseq>TACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILR</Hsp_qseq>
      <Hsp_hseq>STVGTPDYIAPEIFLYQG-YGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMN</Hsp_hseq>
      <Hsp_midline>+  GTP+Y+ PE+   +G + Q  D W++G I Y  L G  PF  ET    +R I+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>1.54836e-11</Hsp_evalue>
      <Hsp_query-from>424</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>898</Hsp_hit-from>
      <Hsp_hit-to>1049</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>179</Hsp_align-len>
      <Hsp_qseq>LAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGE-----LFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFIT--DFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPF</Hsp_qseq>
      <Hsp_hseq>MATLNKNSQENILKLLDFFEDDD--YYYIETPVHGETGSIDLFDVIEFKKDMVEHEAKLVFKQVVASIKHLHDQGIVHRDIKDENVI-----VDSHGFVKLIDFGSAAYIKS-----------------GP---FDVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLYTIIYKENPY</Hsp_hseq>
      <Hsp_midline>+A L +    N+++L++ FE     Y  +E    GE     LFD I  +    E +A      ++   ++LH  GI HRD+K EN++      DS  F+   DFG A  +++                 GP        GT +Y  PEVL       +  D+WA+GV+ Y ++    P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YJR059W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:545787:548243:1 gene:YJR059W transcript:YJR059W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK2 description:Serine/threonine protein kinase; involved in regulation of ion transport across plasma membrane; carboxyl terminus is essential for glucose-dependent Pma1p activation via phosphorylation of Pma1p-Ser899; enhances spermine uptake; PTK2 has a paralog, PTK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003820]</Hit_def>
  <Hit_accession>YJR059W</Hit_accession>
  <Hit_len>818</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>1.66881e-11</Hsp_evalue>
      <Hsp_query-from>304</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>261</Hsp_hit-from>
      <Hsp_hit-to>482</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>240</Hsp_align-len>
      <Hsp_qseq>IGRGSFSSVVRAEHRSSRQP--YAIKLVETSATEGREA----CACELAVLRRVRHP-NVVQLIEVFETPTRTY------LVMELATGGELFDRILARG----SFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLS-----------RRGAFTQAVDMWAIGVISYILLSGTMPF</Hsp_qseq>
      <Hsp_hseq>IGSGG-SSEVRKVKSSYRQKDVYALKKLNMIYHESPEKFYKRCSKEFIIAKHLSHNVHITNTFYLLKVPTTTYTTRGWGFIMELGVK-DLFQLMERTGWKNVPFNEKYCL--FKQVAQGIKFCHDNGIAHRDLKPENVLISKEGI---CKLTDFGISDWYHV-----------IPHDYTSPVKTCQGMIGSPPYTPPEVMYFDAKKHYPEKFQKPYNPLAMDSYALGIMLITMINNIIPF</Hsp_hseq>
      <Hsp_midline>IG G  SS VR    S RQ   YA+K +     E  E     C+ E  + + + H  ++     + + PT TY       +MEL    +LF  +   G     F E+        + +G ++ H  GIAHRDLKPEN+L    G      +TDFG++                   +   P    +   G+P Y PPEV+            ++     A+D +A+G++   +++  +PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YDL214C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:74446:76545:-1 gene:YDL214C transcript:YDL214C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR2 description:Serine/threonine protein kinase; inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance; PRR2 has a paralog, NPR1, that arose from the whole genome duplication [Source:SGD;Acc:S000002373]</Hit_def>
  <Hit_accession>YDL214C</Hit_accession>
  <Hit_len>699</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>2.05283e-11</Hsp_evalue>
      <Hsp_query-from>274</Hsp_query-from>
      <Hsp_query-to>987</Hsp_query-to>
      <Hsp_hit-from>356</Hsp_hit-from>
      <Hsp_hit-to>581</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>247</Hsp_align-len>
      <Hsp_qseq>VTAKY-DLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGREA-------CACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFE-EETRSRLFRAILRGK</Hsp_qseq>
      <Hsp_hseq>VSRKYRDLDVVLGEGSGGKVKLVQRVLDNKVFALK--EYRSKKKRESERKYIKNIISEYCIASTLKNPNICETLEILYEKGKIFQILEYCEY-DLFSLVMSEKMHYE-EICCLFKQLINGVKYLHDIGLSHRDLKLDNCVVTRRGI---LKLIDFGASS-----VFHYPLSSQMIEAN---------GIVGSDPYLSPEVFYFNEYDPRALDVWSVGIIFFCMITRRFPWKYPKVKDVQFKAFCSGR</Hsp_hseq>
      <Hsp_midline>V+ KY DL  ++G GS   V   +     + +A+K  E  + + RE+          E  +   +++PN+ + +E+     + + ++E     +LF  +++     E +       L+ G +YLH +G++HRDLK +N +    G    L + DFG +        H     +  E N            G+  Y+ PEV        +A+D+W++G+I + +++   P++  + +   F+A   G+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>2.10219e-11</Hsp_evalue>
      <Hsp_query-from>304</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>8</Hsp_hit-from>
      <Hsp_hit-to>222</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>230</Hsp_align-len>
      <Hsp_qseq>IGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGREACACELAVLRRVR----HPNVVQLIEVFETPTRTYLVMELATGGELFDRI-LARG-------SFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESC---VRTACGTPEYMPPEVLSRRGA---FTQAVDMWAIGVISYILLSGTMPF</Hsp_qseq>
      <Hsp_hseq>IQSGTFSTVYKAWSTTHNRYVALKITPKYKT-SEANMKNEYDVMKILSSCNPHPNICSMLDFYTDDSYYIMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQIDMQKIIKQLCSAISFAHSLGIAHRDIKPENILLTING--------DIKLADWGHAIQSPKSNDFQIGTDNYRAPETFSGRVSNSCFKKNF------DRSSAPLYNTYQADYWSLGATIFYLMFGDCLF</Hsp_hseq>
      <Hsp_midline>I  G+FS+V +A   +  +  A+K+     T        E  V++ +     HPN+  +++ +   +   +V+E    G+L+D + +A+        S  + D  + +  L     + H+LGIAHRD+KPEN+L    G        D  LA    A Q       +   +N   PE+    V  +C    +       R  A    T   D W++G   + L+ G   F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YKL168C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:131288:133462:-1 gene:YKL168C transcript:YKL168C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KKQ8 description:Putative serine/threonine protein kinase with unknown cellular role; KKQ8 has a paralog, HAL5, that arose from the whole genome duplication [Source:SGD;Acc:S000001651]</Hit_def>
  <Hit_accession>YKL168C</Hit_accession>
  <Hit_len>724</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>3.40372e-11</Hsp_evalue>
      <Hsp_query-from>451</Hsp_query-from>
      <Hsp_query-to>960</Hsp_query-to>
      <Hsp_hit-from>494</Hsp_hit-from>
      <Hsp_hit-to>651</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>175</Hsp_align-len>
      <Hsp_qseq>PNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTER----DAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFT-QAVDMWAIGVISYILLSGTMPFEEETRSR</Hsp_qseq>
      <Hsp_hseq>PNILNVFDILEDSSSFIEVMEFCPAGDLYGMLVGKSKLKGRLHPLEADCFMKQLLHGVKFMHDHGIAHCDLKPENILFYPHGL---LKICDFGTSSVFQTAWERRVHAQ--------------KGIIGSEPYVAPEEFVDGEYYDPRLIDCWSCGVVYITMILGHYLWKVASREK</Hsp_hseq>
      <Hsp_midline>PN++ + ++ E  +    VME    G+L+  ++ +     R    +A   +  LL G +++H  GIAH DLKPEN+L+Y  G    L I DFG +   +                        +   G+  Y+ PE       +  + +D W+ GV+   ++ G   ++  +R +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>71</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>4.47325e-11</Hsp_evalue>
      <Hsp_query-from>304</Hsp_query-from>
      <Hsp_query-to>942</Hsp_query-to>
      <Hsp_hit-from>41</Hsp_hit-from>
      <Hsp_hit-to>241</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>230</Hsp_align-len>
      <Hsp_qseq>IGRGSFSSVVRA----EHRSSRQPYAIKLVETSATEGREACACELAVLRRVRHPNVVQLIEVFE--TPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLE-----------GARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFE</Hsp_qseq>
      <Hsp_hseq>IGRGAFGTVVQAYLTQDKKNWLGPFAIKKVPAHT----EYKSRELQILRIADHPNIVKLQYFFTHLSPQDNKVYQHLAM--ECLPETLQIE--INRYVTNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLV--DPETGVLKICDFGSAKKL--------------EHN----QPSISYICSR-FYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQ</Hsp_hseq>
      <Hsp_midline>IGRG+F +VV+A    + ++   P+AIK V        E  + EL +LR   HPN+V+L   F   +P    +   LA   E     L       R     L M L+           G  YLH LG+ HRD+KP N+L         L I DFG A  +              E N    +  +   C    Y  PE++     +T  +D+W +G +   +L G   F+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>72</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>7.38991e-11</Hsp_evalue>
      <Hsp_query-from>256</Hsp_query-from>
      <Hsp_query-to>906</Hsp_query-to>
      <Hsp_hit-from>28</Hsp_hit-from>
      <Hsp_hit-to>239</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>234</Hsp_align-len>
      <Hsp_qseq>AKFDARVTAKYDLKALIGRGSFSSV--VRAEHRSSRQPYAIKLVETSATEGREACACELAVLRRVR----------HPNVVQLIEVFETPTRTYLVMELATGGELFDRILARG-----SFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVI</Hsp_qseq>
      <Hsp_hseq>AKERISIPGYYEIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNK-------EILLKRAIRELKFMNFFKGHKNIVNLIDLEIVTSSPY--DGLYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGC---LKICDFGLARGIHAGFF----------KCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCI</Hsp_hseq>
      <Hsp_midline>AK    +   Y++   +G+G++ +V  V+ + RS     A+K +     +       E+ + R +R          H N+V LI++    +  Y    L    EL D  LA+        +E      L  +L G +Y+H+  + HRDLKP N+L    G    L I DFGLA  + AG            +     +  +     T  Y  PE+L     ++++VD+WA+G I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>73</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>7.62746e-11</Hsp_evalue>
      <Hsp_query-from>304</Hsp_query-from>
      <Hsp_query-to>906</Hsp_query-to>
      <Hsp_hit-from>47</Hsp_hit-from>
      <Hsp_hit-to>238</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>217</Hsp_align-len>
      <Hsp_qseq>IGRGSFSSVVRAEHRSSR----QPYAIKLVETSATEGREACACELAVLRRVRHPNVVQLIEVFETPTRT---------YLVMEL---ATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVI</Hsp_qseq>
      <Hsp_hseq>IGHGSFGTVTQSILSSNSIEWLGPYAIKRVVKSP----KVQSLELEILQNIRHPNLVTLEFFFESHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGIAK--VCDFGSAQRL-----------------DDNTE--LKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCI</Hsp_hseq>
      <Hsp_midline>IG GSF +V ++   S+      PYAIK V  S     +  + EL +L+ +RHPN+V L   FE+   T           VME        E+ +          +        +L     LH++ I H DLKP N+L       ++  + DFG A  +                 +D  E  ++T   +  Y  PE+L     +T  +D+W++G I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>74</Hit_num>
  <Hit_id>YDR247W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:956013:957398:1 gene:YDR247W transcript:YDR247W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VHS1 description:Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; VHS1 has a paralog, SKS1, that arose from the whole genome duplication [Source:SGD;Acc:S000002655]</Hit_def>
  <Hit_accession>YDR247W</Hit_accession>
  <Hit_len>461</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>8.71597e-11</Hsp_evalue>
      <Hsp_query-from>433</Hsp_query-from>
      <Hsp_query-to>906</Hsp_query-to>
      <Hsp_hit-from>113</Hsp_hit-from>
      <Hsp_hit-to>263</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>175</Hsp_align-len>
      <Hsp_qseq>LRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERD--AARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAV---------------DMWAIGVI</Hsp_qseq>
      <Hsp_hseq>LRVHHHKNIVTIHEVLQSAVCTFIVMDYYPT-DLFTSIVDNRHFVTNGLLVKKVFLQICSALNYCHEHGIYHCDIKPENLLL---DTEDNVFLCDFGLSTTSTYIK----------------PNVCI----GSSYYMPPERISFDGRVSSSKSGGHKLGKVCPSCNGDLWSLGII</Hsp_hseq>
      <Hsp_midline>LR   H N+V + EV ++   T++VM+     +LF  I+    F        +    +     Y H  GI H D+KPENLL      +  +F+ DFGL+      +                P  C+    G+  YMPPE +S  G  + +                D+W++G+I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>75</Hit_num>
  <Hit_id>YDL025C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:405344:407206:-1 gene:YDL025C transcript:YDL025C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RTK1 description:Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002183]</Hit_def>
  <Hit_accession>YDL025C</Hit_accession>
  <Hit_len>620</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>1.76034e-10</Hsp_evalue>
      <Hsp_query-from>412</Hsp_query-from>
      <Hsp_query-to>966</Hsp_query-to>
      <Hsp_hit-from>354</Hsp_hit-from>
      <Hsp_hit-to>523</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>191</Hsp_align-len>
      <Hsp_qseq>CACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRT--ACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRS----RLF</Hsp_qseq>
      <Hsp_hseq>VTTEFCIGSTLHHENIVETLDMLTEGDTYLLVMEYAPY-DFFNLVMS-NLMTQDEVNCYFKQLCHGVNYLHSMGLAHRDLKLDNCVV---TKDGILKLIDFGSAVVFQYPYE----------------DTIVKSHGIVGSDPYLAPELLKQTSYDPRVADVWSIAIIFYCMVLKRFPWKAPKKSFNSFRLF</Hsp_hseq>
      <Hsp_midline>   E  +   + H N+V+ +++        LVME A   + F+ +++    T+ +       L  G  YLH++G+AHRDLK +N +      D  L + DFG A   +                    ++ V++    G+  Y+ PE+L +     +  D+W+I +I Y ++    P++   +S    RLF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>76</Hit_num>
  <Hit_id>YKL198C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:68232:70220:-1 gene:YKL198C transcript:YKL198C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK1 description:Putative serine/threonine protein kinase; regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein; PTK1 has a paralog, PTK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001681]</Hit_def>
  <Hit_accession>YKL198C</Hit_accession>
  <Hit_len>662</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>2.03713e-10</Hsp_evalue>
      <Hsp_query-from>289</Hsp_query-from>
      <Hsp_query-to>945</Hsp_query-to>
      <Hsp_hit-from>197</Hsp_hit-from>
      <Hsp_hit-to>425</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>248</Hsp_align-len>
      <Hsp_qseq>DLKALIGRGSFSSV--VRAEHRSSRQPYAIKLVETSATEGREA----CACELAVLRRV-RHPNVVQLIEVFETPTRTY------LVMELATGGELFDRILARGSFTERDAARA-----LSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVL---SRRGAFTQ--------AVDMWAIGVISYILLSGTMPFEE</Hsp_qseq>
      <Hsp_hseq>DENKTIGWGGSCEVRKIRSKYRK-KDVFALKKLNMIYNETPEKFYKRCSKEFIIAKQLSHHVHITNTFLLVKVPTTVYTTRGWGFVMELGLR-DLFAMIQKSG---WRSVALAEKFCIFKQVACGVKFCHDQGIAHRDLKPENVLL---SPDGVCKLTDFGISDWYHT-----------DPHDLSSPVKKCAGMIGSPPYAPPEVMFYDSKKHYDTELQQPYDPRALDCYGLGIILMTLVNNVIPFLE</Hsp_hseq>
      <Hsp_midline>D    IG G    V  +R+++R  +  +A+K +     E  E     C+ E  + +++  H ++     + + PT  Y       VMEL    +LF  I   G    R  A A        +  G ++ H  GIAHRDLKPEN+L      D    +TDFG++                   +   P        G+P Y PPEV+   S++   T+        A+D + +G+I   L++  +PF E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>77</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>2.10393e-10</Hsp_evalue>
      <Hsp_query-from>304</Hsp_query-from>
      <Hsp_query-to>906</Hsp_query-to>
      <Hsp_hit-from>66</Hsp_hit-from>
      <Hsp_hit-to>272</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>228</Hsp_align-len>
      <Hsp_qseq>IGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGREACAC--ELAVLRRVRHPNVVQLIEVF--ETPTRT----------------YLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLA-------GNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVI</Hsp_qseq>
      <Hsp_hseq>LGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLS--GVLHN---PRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGV---LKLADFGLARLYYGCPPNLKYPGGA-------------GSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCV</Hsp_hseq>
      <Hsp_midline>+G+G+F  V +  H  +++  A+K +  S  +         E+ +L+R+ H N+++LIE+    +P  T                Y+V +L+  G L +    R +    D    +  +LEG  Y+H     HRD+K  N+L  H G    L + DFGLA        N++   G              G  +   +   T  Y  PE++     +T AVD+W +G +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>78</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>3.02736e-10</Hsp_evalue>
      <Hsp_query-from>265</Hsp_query-from>
      <Hsp_query-to>981</Hsp_query-to>
      <Hsp_hit-from>16</Hsp_hit-from>
      <Hsp_hit-to>247</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>252</Hsp_align-len>
      <Hsp_qseq>DARVTAKYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGREACAC-----ELAVLRRVR-HPNVVQL--IEVFETPTRT----YLVMELATGGELFDRILARGS-FTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILR</Hsp_qseq>
      <Hsp_hseq>DFSVDKRFQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSK-TLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECD--MHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLV---NADCQLKICDFGLA--------------RGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQ</Hsp_hseq>
      <Hsp_midline>D  V  ++ L   IG G++  V  A    + +   + + + +    +    C     EL +LR  R H N+  L  +++   P  +    YL  EL        +I+  G   T+         +L G +Y+H+  + HRDLKP NLL     AD +L I DFGLA              RG+ EN       +     T  Y  PE++     +T+A+D+W+ G I    L G   F+ +        IL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>79</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>3.49546e-10</Hsp_evalue>
      <Hsp_query-from>406</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>499</Hsp_hit-from>
      <Hsp_hit-to>657</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>178</Hsp_align-len>
      <Hsp_qseq>EACACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPF</Hsp_qseq>
      <Hsp_hseq>DALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGC---VKITDFGISKKLSPL---------------NKKQNKRASLQGSVFWMSPEVV-KQTATTAKADIWSTGCVVIEMFTGKHPF</Hsp_hseq>
      <Hsp_midline>+A   E+ +L+ + H N+V      +      + +E   GG +   +   G F E         +L G  YLH   I HRD+K  N+L    G    + ITDFG++  +                  +  ++   +  G+  +M PEV+ ++ A T   D+W+ G +   + +G  PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>80</Hit_num>
  <Hit_id>YDL028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:400997:403291:-1 gene:YDL028C transcript:YDL028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MPS1 description:Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]</Hit_def>
  <Hit_accession>YDL028C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>1.16478e-09</Hsp_evalue>
      <Hsp_query-from>280</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>438</Hsp_hit-from>
      <Hsp_hit-to>654</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>53</Hsp_gaps>
      <Hsp_align-len>245</Hsp_align-len>
      <Hsp_qseq>AKYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGR--EACACELAVLRRVR-HPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAA----RALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVR----TACGTPEYMPPEVL--------------SRRGAFTQAVDMWAIGVISYILLSGTMPF</Hsp_qseq>
      <Hsp_hseq>SQYEKIELLGRGGSSRVYKVKGSGNRV-YALKRVSFDAFDDSSIDGFKGEIELLEKLKDQKRVIQLLDYEMGDGLLYLIME--CGDHDLSQILNQRSGMPLDFNFVRFYTKEMLL-CIKVVHDAGIVHSDLKPANFVL----VKGILKIIDFGIANAV--------------------PEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYGKPPY</Hsp_hseq>
      <Hsp_midline>++Y+   L+GRG  S V + +   +R  YA+K V   A +    +    E+ +L +++    V+QL++        YL+ME   G     +IL + S    D          MLL   + +H  GI H DLKP N +         L I DFG+A  V                    PE  V     T  GTP YM PE L                +    +  DMW+ G I Y ++ G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>81</Hit_num>
  <Hit_id>YJL165C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:106894:109461:-1 gene:YJL165C transcript:YJL165C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HAL5 description:Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters; HAL5 has a paralog, KKQ8, that arose from the whole genome duplication [Source:SGD;Acc:S000003701]</Hit_def>
  <Hit_accession>YJL165C</Hit_accession>
  <Hit_len>855</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>1.73584e-09</Hsp_evalue>
      <Hsp_query-from>451</Hsp_query-from>
      <Hsp_query-to>927</Hsp_query-to>
      <Hsp_hit-from>601</Hsp_hit-from>
      <Hsp_hit-to>765</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>183</Hsp_align-len>
      <Hsp_qseq>PNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTER-----------------------DAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFT-QAVDMWAIGVISYILLSG</Hsp_qseq>
      <Hsp_hseq>PNILKILDLMEYSNSFVEVMEFCASGDLYS-LLTRNNISNESNNGSSRLIQTVKEGSGSPLHPLEADCFMKQLLNGVQYMHDHGIAHCDLKPENILFQPNGL---LKICDFGTSSVFQTAWEKHVHFQSG--------------AMGSEPYVAPEEFIRDAEYDPRLVDCWSCGIVYCTMVMG</Hsp_hseq>
      <Hsp_midline>PN+++++++ E       VME    G+L+  +L R + +                         +A   +  LL G +Y+H  GIAH DLKPEN+L+   G    L I DFG +   +           G              A G+  Y+ PE   R   +  + VD W+ G++   ++ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>82</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>1.88296e-09</Hsp_evalue>
      <Hsp_query-from>274</Hsp_query-from>
      <Hsp_query-to>927</Hsp_query-to>
      <Hsp_hit-from>9</Hsp_hit-from>
      <Hsp_hit-to>222</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>240</Hsp_align-len>
      <Hsp_qseq>VTAKYDLKALIGRGSFSSVVRAEHRSS--------RQPYAIKLVETSATEGREACACELAVLRRVR-HPNVVQLIE-----VFETPTRTYLVMELATGGELFDRILAR-----GSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCV---RTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSG</Hsp_qseq>
      <Hsp_hseq>IPSQYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRTIR-------EIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETD--LQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLL---NSNCDLKVCDFGLARCLAS--------------SSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSG</Hsp_hseq>
      <Hsp_midline>+ ++Y L  LIG G++ +V  A H+ S         QP++ KL  T           E+ +LR    H N++ +++       +     YLV EL        +++        + ++         +L   + +H+  + HRD+KP NLL     ++  L + DFGLA  + +              + D  E+ V        T  Y  PE++     +T A+D+W+ G I   ++SG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>83</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>7.99615e-09</Hsp_evalue>
      <Hsp_query-from>304</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>197</Hsp_hit-from>
      <Hsp_hit-to>404</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>232</Hsp_align-len>
      <Hsp_qseq>IGRGSFSSVVRAEHRSSRQPYAIKL--VETSATEGREACACELAVLRRVR-HPNVVQLIEVF---ETPTRTYLVMELATGGEL------FDRILARGS-------FTERDAARALSMLLEGARYLH-ALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPF</Hsp_qseq>
      <Hsp_hseq>IGAGNSGTVVKALHVPDSKIVAKKTIPVEQNNSTIINQLVRELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKG---QIKLCDFGVSKKL--------------------INSIADTFVGTSTYMSPERI-QGNVYSIKGDVWSLGLMIIELVTGEFPL</Hsp_hseq>
      <Hsp_midline>IG G+  +VV+A H    +  A K   VE + +        EL++++ V+ H N++     +          ++ME +  G L      + R + RG+       F E   ++    +L G  +L+    I HRD+KP N+L    G   ++ + DFG++  +                      S   T  GT  YM PE + +   ++   D+W++G++   L++G  P </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>84</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>8.99484e-09</Hsp_evalue>
      <Hsp_query-from>280</Hsp_query-from>
      <Hsp_query-to>906</Hsp_query-to>
      <Hsp_hit-from>6</Hsp_hit-from>
      <Hsp_hit-to>201</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>217</Hsp_align-len>
      <Hsp_qseq>AKYDLKALIGRGSFSSVVRAEHRSSRQPYAI----KLVETSATEGREACAC-ELAVLRRVRHPNVVQLIEVFETPT-RTYLVME-LATGGELFDRILARGSFTERDAARALSM-LLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVI</Hsp_qseq>
      <Hsp_hseq>ANYKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLI---NKDGNLKLGDFGLA---RAFGV---------------PLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCI</Hsp_hseq>
      <Hsp_midline>A Y     +G G++  V +A      Q   +    K+   S  EG  + A  E+++L+ ++  N+V+L ++  +   + YLV E L    + +   + +      D  +   M L +G  Y H+  I HRDLKP+NLL      D  L + DFGLA   RA                  P         T  Y  PEVL     ++  VD W+IG I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>85</Hit_num>
  <Hit_id>YPL236C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:101608:102702:-1 gene:YPL236C transcript:YPL236C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ENV7 description:Vacuolar membrane protein kinase; negatively regulates membrane fusion; associates with vacuolar membrane through palmitoylation of one or more cysteines in consensus sequence; vacuolar membrane association is essential to its kinase activity; mutant shows defect in CPY processing; ortholog of human serine/threonine kinase 16 (STK16) [Source:SGD;Acc:S000006157]</Hit_def>
  <Hit_accession>YPL236C</Hit_accession>
  <Hit_len>364</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>9.13132e-09</Hsp_evalue>
      <Hsp_query-from>625</Hsp_query-from>
      <Hsp_query-to>1023</Hsp_query-to>
      <Hsp_hit-from>208</Hsp_hit-from>
      <Hsp_hit-to>333</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>138</Hsp_align-len>
      <Hsp_qseq>ALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRR--GAFTQAVDMWAIGVISYILLSGTMPFEEETR---SRLFRAILRGKYSYVGEVRAEEA</Hsp_qseq>
      <Hsp_hseq>SIAYAHRDITPSNILF---SSDGLPVIGDLGSCSQADITIENRHQLSELQEWVNDN--------CTLP-YTPPELLNLKLNQVLSSKVDIWSLGCTFYTLMFGISPFEREEQIHGASLTYAINTGKYSFPRNSRFSEG</Hsp_hseq>
      <Hsp_midline>++  AHRD+ P N+L+    +D    I D G          +        E   D         C  P Y PPE+L+ +     +  VD+W++G   Y L+ G  PFE E +   + L  AI  GKYS+    R  E </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>86</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>1.19754e-08</Hsp_evalue>
      <Hsp_query-from>379</Hsp_query-from>
      <Hsp_query-to>963</Hsp_query-to>
      <Hsp_hit-from>192</Hsp_hit-from>
      <Hsp_hit-to>372</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>202</Hsp_align-len>
      <Hsp_qseq>VETSATEGREACAC-ELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTE------RDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRL</Hsp_qseq>
      <Hsp_hseq>VEQLHYTGISQSACREMALCRELHNKHLTTLVEIFLERKCVHMVYEYAEHDLL--QIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMV---TIDGCVKIGDLGLARKFHNMLQTLYT----------GDKVVV-----TIWYRAPELLLGARHYTPAVDLWSVGCI-FAELIGLQPIFKGEEAKL</Hsp_hseq>
      <Hsp_midline>VE     G    AC E+A+ R + + ++  L+E+F      ++V E A    L  +I+   S  E      R     +  LL+G  YLH   + HRDLKP N++      D  + I D GLA                      G +  V     T  Y  PE+L     +T AVD+W++G I +  L G  P  +   ++L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>87</Hit_num>
  <Hit_id>YOR061W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:441534:442553:1 gene:YOR061W transcript:YOR061W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA2 description:Alpha&apos; catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000005587]</Hit_def>
  <Hit_accession>YOR061W</Hit_accession>
  <Hit_len>339</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>1.51328e-08</Hsp_evalue>
      <Hsp_query-from>280</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>48</Hsp_hit-from>
      <Hsp_hit-to>243</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>221</Hsp_align-len>
      <Hsp_qseq>AKYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGREACACELAVLRRVRH-PNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPF</Hsp_qseq>
      <Hsp_hseq>SNYEIINKIGRGKYSEVFSGRCIVNNQKCVIKVLKPVKMK---KIYRELKILTNLTGGPNVVGLYDIVQDADSKIPALIFEEIKNVDFRTLY-PTFKLPDIQYYFTQLLIALDYCHSMGIMHRDVKPQNVMI--DPTERKLRLIDWGLA-----------------EFYHPGVDYNVRVA--SRYHKGPELLVNLNQYDYSLDLWSVGCMLAAIVFKKEPF</Hsp_hseq>
      <Hsp_midline>+ Y++   IGRG +S V       + Q   IK+++    +       EL +L  +   PNVV L ++ +        +       +  R L   +F   D     + LL    Y H++GI HRD+KP+N++      + +L + D+GLA                 E    G +  VR A  +  +  PE+L     +  ++D+W++G +   ++    PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>88</Hit_num>
  <Hit_id>YPL026C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:500675:502183:-1 gene:YPL026C transcript:YPL026C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKS1 description:Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway; SKS1 has a paralog, VHS1, that arose from the whole genome duplication [Source:SGD;Acc:S000005947]</Hit_def>
  <Hit_accession>YPL026C</Hit_accession>
  <Hit_len>502</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>2.32751e-08</Hsp_evalue>
      <Hsp_query-from>421</Hsp_query-from>
      <Hsp_query-to>906</Hsp_query-to>
      <Hsp_hit-from>109</Hsp_hit-from>
      <Hsp_hit-to>264</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>180</Hsp_align-len>
      <Hsp_qseq>ELAVLRRVR-HPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDA--ARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPE-VLSRRGAFTQAV--------------DMWAIGVI</Hsp_qseq>
      <Hsp_hseq>EIAFQLRVQSHGNIVKIHQVLESSIATFIVMDYY-DRDLFTSIVDDKHFVNHGILIKKVFLQLCSALDHCHRLGIYHCDIKPENVLL---DRNDNAYLCDFGLSTKSKYL----------------APNVCV----GSSYYMAPERILYCLNTTTNGIHVDECCSSLPTDTGDIWSLGII</Hsp_hseq>
      <Hsp_midline>E+A   RV+ H N+V++ +V E+   T++VM+     +LF  I+    F        +    L     + H LGI H D+KPEN+L      +   ++ DFGL+   +                   P  CV    G+  YM PE +L      T  +              D+W++G+I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>89</Hit_num>
  <Hit_id>YNL183C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:293137:295509:-1 gene:YNL183C transcript:YNL183C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NPR1 description:Protein kinase; stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p; negatively regulates Ldb19p-mediated endocytosis through phosphorylation of Ldb19p, which prevents its association with the plasma membrane; Npr1p activity is negatively regulated via phosphorylation by the TOR complex; NPR1 has a paralog, PRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005127]</Hit_def>
  <Hit_accession>YNL183C</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>3.4445e-08</Hsp_evalue>
      <Hsp_query-from>325</Hsp_query-from>
      <Hsp_query-to>987</Hsp_query-to>
      <Hsp_hit-from>451</Hsp_hit-from>
      <Hsp_hit-to>658</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>227</Hsp_align-len>
      <Hsp_qseq>SVVRAEHRSSRQPYAIKLVET-----SATEGREACACELAVLRRVRHPNVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFE-EETRSRLFRAILRGK</Hsp_qseq>
      <Hsp_hseq>SVKLAQRISDNKIFAVKEFRTKFENESKRDYVKKITSEYCIGTTLNHPNIIETIEIVYENDRILQVMEYCEY-DLF-AIVMSNKMSYEEICCCFKQILTGVQYLHSIGLAHRDLKLDNCVINEKGI---VKLIDFGAA----------VVFSYPFSKNLVEASGIV----GSDPYLAPEVCIFAKYDPRPVDIWSSAIIFACMILKKFPWKIPKLRDNSFKLFCSGR</Hsp_hseq>
      <Hsp_midline>SV  A+  S  + +A+K   T     S  +  +    E  +   + HPN+++ IE+     R   VME     +LF  I+     +  +       +L G +YLH++G+AHRDLK +N +    G    + + DFG A                  +N       V    G+  Y+ PEV        + VD+W+  +I   ++    P++  + R   F+    G+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>90</Hit_num>
  <Hit_id>YIL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:183937:186369:1 gene:YIL095W transcript:YIL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRK1 description:Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton and reduces endocytic ability of cell through the phosphorylation of the Pan1p-Sla1p-End3p protein complex; PRK1 has a paralog, ARK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001357]</Hit_def>
  <Hit_accession>YIL095W</Hit_accession>
  <Hit_len>810</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>1.17941e-07</Hsp_evalue>
      <Hsp_query-from>313</Hsp_query-from>
      <Hsp_query-to>996</Hsp_query-to>
      <Hsp_hit-from>31</Hsp_hit-from>
      <Hsp_hit-to>260</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>249</Hsp_align-len>
      <Hsp_qseq>GSFSSVVRAEHRSSRQPYA------IKLVETSATEGREACACELAVLRRVRH-PNVVQLIE------VFETPTRTYLVMELATGGELFDRILAR--GSFTERDAARALSMLLEGARYLHALG--IAHRDLKPENLLYYHPGADSRLF-ITDFG-LAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEV--LSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGKYSY</Hsp_qseq>
      <Hsp_hseq>GGFAQVYTAE-ISPPDPYSNANIACLKRVIVPHKQGLNTLRAEVDAMKLLRNNKHVVSYIDSHAARSVNGIAYEVFVLMEFCERGGLIDFMNTRLQNRLQESEILEIMSQTVQGITAMHALQPPLIHRDIKIENVLISHDG----LYKVCDFGSVSGVIRPPRNTQ-------EFNYVQHDILTNT---TAQYRSPEMIDLYRGLPIDEKSDIWALGVFLYKICYYTTPFEKSGEA----GILHARYQY</Hsp_hseq>
      <Hsp_midline>G F+ V  AE  S   PY+      +K V     +G      E+  ++ +R+  +VV  I+      V       +++ME    G L D +  R      E +    +S  ++G   +HAL   + HRD+K EN+L  H G    L+ + DFG ++G +R  +          E N    +    T   T +Y  PE+  L R     +  D+WA+GV  Y +   T PFE+   +     IL  +Y Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>91</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>1.34944e-07</Hsp_evalue>
      <Hsp_query-from>274</Hsp_query-from>
      <Hsp_query-to>951</Hsp_query-to>
      <Hsp_hit-from>35</Hsp_hit-from>
      <Hsp_hit-to>244</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>235</Hsp_align-len>
      <Hsp_qseq>VTAKYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGREACACELAVLRRVRHPNVVQLIEVF---ETPTRTYLVMELATGGE-LFDR----ILARGSFTERDAARALSMLLEGARYLHAL-GIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPFEEET</Hsp_qseq>
      <Hsp_hseq>VQISFPTTEVVGHGSFGVVFATVIQETNEKVAIKKV----LQDKRFKNRELEIMKMLSHINIIDLKYFFYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLL-VDPETWS-LKLCDFGSAKQLKPT------------------EPNVSYICSR-YYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGES</Hsp_hseq>
      <Hsp_midline>V   +    ++G GSF  V     + + +  AIK V     + +     EL +++ + H N++ L   F   ++    YL + L    + L+ R    +  R   +  +    +  L +   YLH    + HRD+KP+NLL   P   S L + DFG A  ++                    E  V   C    Y  PE++     +T  +D+W+ G +   LL G   F  E+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>92</Hit_num>
  <Hit_id>YIL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:287790:288908:-1 gene:YIL035C transcript:YIL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA1 description:Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000001297]</Hit_def>
  <Hit_accession>YIL035C</Hit_accession>
  <Hit_len>372</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>1.41779e-07</Hsp_evalue>
      <Hsp_query-from>448</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>130</Hsp_hit-from>
      <Hsp_hit-to>271</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>166</Hsp_align-len>
      <Hsp_qseq>HPNVVQLIEVFETPTRTY--LVMELATGGELFDRILARGSFTERDAARALSMLLEGARYLHALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVISYILLSGTMPF</Hsp_qseq>
      <Hsp_hseq>HANIIHLFDIIKDPISKTPALVFEYVDNVDF--RILY-PKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRL--IDWGLA-----------------EFYHVNMEYNVRVASRF--FKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPF</Hsp_hseq>
      <Hsp_midline>H N++ L ++ + P      LV E     +   RIL     T+ +    +  LL+   Y H++GI HRD+KP N++  H     RL   D+GLA                 E      E  VR A     +  PE+L     +  ++D+W+ G +   ++    PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>93</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>2.0401e-07</Hsp_evalue>
      <Hsp_query-from>247</Hsp_query-from>
      <Hsp_query-to>906</Hsp_query-to>
      <Hsp_hit-from>431</Hsp_hit-from>
      <Hsp_hit-to>642</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>236</Hsp_align-len>
      <Hsp_qseq>KYRAKFDARVTAKYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGREACACELAVLRRVRHP---------NVVQLIEVFETPTRTYLVMELATGGELFDRILARGSFTER---DAARALSMLLE---GARYLH-ALGIAHRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVI</Hsp_qseq>
      <Hsp_hseq>KLSANPDSHLFEKFTNVHSIGKGQFSTVYQVTFAQTNKKYAIKAIKPNKYNSLKRILLEIKILNEVTNQITMDQEGKEYIIDYISSWKFQNSYYIMTELCENGNL-DGFLQEQVIAKKKRLEDWRIWKIIVELSLALRFIHDSCHIVHLDLKPANVMITFEG---NLKLGDFGMATHLPLEDKSF--------ENE-----------GDREYIAPEIIS-DCTYDYKADIFSLGLM</Hsp_hseq>
      <Hsp_midline>K  A  D+ +  K+     IG+G FS+V +     + + YAIK ++ +     +    E+ +L  V +           ++  I  ++     Y++ EL   G L D  L      ++   +  R   +++E     R++H +  I H DLKP N++    G    L + DFG+A ++               ENE           G  EY+ PE++S    +    D++++G++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>94</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>2.4426e-07</Hsp_evalue>
      <Hsp_query-from>457</Hsp_query-from>
      <Hsp_query-to>909</Hsp_query-to>
      <Hsp_hit-from>127</Hsp_hit-from>
      <Hsp_hit-to>275</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>169</Hsp_align-len>
      <Hsp_qseq>VVQLIEVF--ETPTRTYLVMELATGGELFDRILARG--SFTERDAARALSMLLEGARYLHALGIAHRDLKPENLL------YYHP------GADSRLFI--TDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVIS</Hsp_qseq>
      <Hsp_hseq>LIQIFEVFIDSENYQLHIVMECMEQN-LYQMMKHRRRRVFSIPSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHV---------------ENKNPYTAYVSTRW----YRSPEILLRSGYYSKPLDIWAFGCVA</Hsp_hseq>
      <Hsp_midline>++Q+ EVF      + ++VME      L+  +  R    F+       LS +L G +++H     HRDLKPEN+L      Y+        G      I   DFGLA +V               EN++   + V T      Y  PE+L R G +++ +D+WA G ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>95</Hit_num>
  <Hit_id>YLL019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:105686:107899:-1 gene:YLL019C transcript:YLL019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KNS1 description:Protein kinase involved in negative regulation of PolIII transcription; effector kinase of the TOR signaling pathway and phosphorylates Rpc53p to regulate ribosome and tRNA biosynthesis; member of the LAMMER family of protein kinases, which are serine/threonine kinases also capable of phosphorylating tyrosine residues; capable of autophosphorylation [Source:SGD;Acc:S000003942]</Hit_def>
  <Hit_accession>YLL019C</Hit_accession>
  <Hit_len>737</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>3.72678e-07</Hsp_evalue>
      <Hsp_query-from>283</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>312</Hsp_hit-from>
      <Hsp_hit-to>447</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>137</Hsp_align-len>
      <Hsp_qseq>KYDLKALIGRGSFSSVVRAEHRSSRQPYAIKLVETSATEGREACACELAVLRRVRHPN------VVQLIEVFETPTRTYLVMELATGGELFDRILARG--SFTERDAARALSMLLEGARYLHALGIAHRDLKPENLL</Hsp_qseq>
      <Hsp_hseq>RFVVKDLLGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDRYREAAKTELRILQTILNNDPQGQFQCLLLRECFDYKNHICLVTDLY-GRSIYDFMCSNGIARFPGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENIL</Hsp_hseq>
      <Hsp_midline>++ +K L+G+G+F  V++         Y    V  +    REA   EL +L+ + + +       + L E F+      LV +L  G  ++D + + G   F           L+    +LH LGI H DLKPEN+L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>96</Hit_num>
  <Hit_id>YFL029C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:78055:79161:-1 gene:YFL029C transcript:YFL029C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CAK1 description:Cyclin-dependent kinase-activating kinase; required for passage through the cell cycle; phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases [Source:SGD;Acc:S000001865]</Hit_def>
  <Hit_accession>YFL029C</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.3654</Hsp_bit-score>
      <Hsp_score>111</Hsp_score>
      <Hsp_evalue>1.78296e-06</Hsp_evalue>
      <Hsp_query-from>598</Hsp_query-from>
      <Hsp_query-to>906</Hsp_query-to>
      <Hsp_hit-from>140</Hsp_hit-from>
      <Hsp_hit-to>233</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>105</Hsp_align-len>
      <Hsp_qseq>LLEGARYLHALGIAHRDLKPENLLYYHPGA--DSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSRRGAFTQAVDMWAIGVI</Hsp_qseq>
      <Hsp_hseq>MVEGIAFLHENKIIHRDIKPQNIMLTNNTSTVSPKLYIIDFGISYDM-----------ANNSQTSAEPMDSKVTDISTGIYKAPEVLFGVKCYDGGVDVWSLLII</Hsp_hseq>
      <Hsp_midline>++EG  +LH   I HRD+KP+N++  +  +    +L+I DFG++ ++             + +    P     T   T  Y  PEVL     +   VD+W++ +I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>97</Hit_num>
  <Hit_id>YKL171W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:127475:130261:1 gene:YKL171W transcript:YKL171W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NNK1 description:Protein kinase; implicated in proteasome function; interacts with TORC1, Ure2 and Gdh2; overexpression leads to hypersensitivity to rapamycin and nuclear accumulation of Gln3; epitope-tagged protein localizes to the cytoplasm [Source:SGD;Acc:S000001654]</Hit_def>
  <Hit_accession>YKL171W</Hit_accession>
  <Hit_len>928</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.3654</Hsp_bit-score>
      <Hsp_score>111</Hsp_score>
      <Hsp_evalue>2.38287e-06</Hsp_evalue>
      <Hsp_query-from>367</Hsp_query-from>
      <Hsp_query-to>723</Hsp_query-to>
      <Hsp_hit-from>476</Hsp_hit-from>
      <Hsp_hit-to>607</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>132</Hsp_align-len>
      <Hsp_qseq>AIKLVETSATEG-REACACELAVLRRVRHPNVVQLIEV-FETPTRTYLVMELATGGELFDRILARGSFTERDAARA--------LSM-LLEGARYLHALGIAHRDLKPENLLYYHPG--ADSRLFITDFGLA</Hsp_qseq>
      <Hsp_hseq>VIKIVKFKGHQNIKKHVLREVAIWRTLKHNRILPLLDWKLDDNYAMYCLTERINDGTLYDLVISWDEFKRSKIPFAERCRLTIFLSLQLLSALKYMHSKTIVHGDIKLENCLLQKEGKKSDWKVFLCDFGMS</Hsp_hseq>
      <Hsp_midline> IK+V+    +  ++    E+A+ R ++H  ++ L++   +     Y + E    G L+D +++   F       A        LS+ LL   +Y+H+  I H D+K EN L    G  +D ++F+ DFG++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>98</Hit_num>
  <Hit_id>YBR059C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:356861:360187:-1 gene:YBR059C transcript:YBR059C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AKL1 description:Ser-Thr protein kinase; member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization [Source:SGD;Acc:S000000263]</Hit_def>
  <Hit_accession>YBR059C</Hit_accession>
  <Hit_len>1108</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.3654</Hsp_bit-score>
      <Hsp_score>111</Hsp_score>
      <Hsp_evalue>2.55229e-06</Hsp_evalue>
      <Hsp_query-from>421</Hsp_query-from>
      <Hsp_query-to>996</Hsp_query-to>
      <Hsp_hit-from>94</Hsp_hit-from>
      <Hsp_hit-to>283</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>206</Hsp_align-len>
      <Hsp_qseq>ELAVLRRVR-HPNVVQLIEVFETPTR-------TYLVMELATGGELFDRILARGS--FTERDAARALSMLLEGARYLHALGIA--HRDLKPENLLYYHPGADSRLFITDFGLAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEV--LSRRGAFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGKYSY</Hsp_qseq>
      <Hsp_hseq>EVEVMKKLKGAPNIVQYFDSNASRRRDGVQGFEVLLLMELCPNKSLLDYMNQRLSTKLTEAEIVKIMYDVALSISQMHYLPVSLIHRDIKIENVLV---DAKNNFKLADFGSTSTCFPIVTTHQDIALLTQN------IYVHT---TPQYRSPEMIDLYRCLPINEKSDIWALGVFLYKLLFFTTPFEMTGQF----AILHSKYEF</Hsp_hseq>
      <Hsp_midline>E+ V+++++  PN+VQ  +   +  R         L+MEL     L D +  R S   TE +  + +  +      +H L ++  HRD+K EN+L     A +   + DFG            Q      +         V T   TP+Y  PE+  L R     +  D+WA+GV  Y LL  T PFE   +     AIL  KY +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>99</Hit_num>
  <Hit_id>YNL020C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:595623:597539:-1 gene:YNL020C transcript:YNL020C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ARK1 description:Serine/threonine protein kinase; involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis; ARK1 has a paralog, PRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004965]</Hit_def>
  <Hit_accession>YNL020C</Hit_accession>
  <Hit_len>638</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.595</Hsp_bit-score>
      <Hsp_score>109</Hsp_score>
      <Hsp_evalue>3.71194e-06</Hsp_evalue>
      <Hsp_query-from>499</Hsp_query-from>
      <Hsp_query-to>996</Hsp_query-to>
      <Hsp_hit-from>106</Hsp_hit-from>
      <Hsp_hit-to>261</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>173</Hsp_align-len>
      <Hsp_qseq>YLVMELATGGELFDRILAR--GSFTERDAARALSMLLEGARYLHALG--IAHRDLKPENLLYYHPGADSRLFITDFG-LAGNVRAXXXXXXXXXXXXEENEDGPESCVRTACGTPEYMPPEVLSR-RG-AFTQAVDMWAIGVISYILLSGTMPFEEETRSRLFRAILRGKYSY</Hsp_qseq>
      <Hsp_hseq>FVLMEYCERGGLIDFMNTRLQNRLHEFEILQIMSQVTQGVAAMHALQPPLIHRDIKIENVLI---SANNEYKLCDFGSVCGIIRPPRNS--------QELSYVQQDILKNT--TAQYRSPEMIDTFRGLPIDEKSDIWALGIFLYKLCYYTTPFEKGGD----LAILSGKFEF</Hsp_hseq>
      <Hsp_midline>+++ME    G L D +  R      E +  + +S + +G   +HAL   + HRD+K EN+L     A++   + DFG + G +R  +          +E     +  ++    T +Y  PE++   RG    +  D+WA+G+  Y L   T PFE+        AIL GK+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>613068755</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055567-RA transcript Note:&quot;Protein of unknown function&quot; offset:99 AED:0.12 eAED:0.12 QI:99|0.71|0.75|1|0.71|0.75|8|338|449</Iteration_query-def>
  <Iteration_query-len>1787</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1143533500</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055568-RA transcript Note:&quot;Similar to DHRS4 Dehydrogenase/reductase SDR family member 4 (Pongo abelii)&quot; offset:0 AED:0.21 eAED:0.26 QI:0|0|0|0.85|0.83|0.71|7|0|323</Iteration_query-def>
  <Iteration_query-len>972</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YMR226C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:721593:722396:-1 gene:YMR226C transcript:YMR226C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YMR226C description:NADP(+)-dependent serine dehydrogenase and carbonyl reductase; acts on serine, L-allo-threonine, and other 3-hydroxy acids; green fluorescent protein fusion protein localizes to the cytoplasm and nucleus; may interact with ribosomes, based on co-purification experiments [Source:SGD;Acc:S000004839]</Hit_def>
  <Hit_accession>YMR226C</Hit_accession>
  <Hit_len>267</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>2.48753e-07</Hsp_evalue>
      <Hsp_query-from>58</Hsp_query-from>
      <Hsp_query-to>618</Hsp_query-to>
      <Hsp_hit-from>11</Hsp_hit-from>
      <Hsp_hit-to>206</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>198</Hsp_align-len>
      <Hsp_qseq>LAGKIAVVTGSTYGIGLAIARRL--AQHG-AHVVVSSRTXXXXXXXXXXXXXXGLNVTGIVCH--VGDADQRTKLIKETVSKLGGLDILVLNAAV---NPYVGPL-LNATAEVLDVNLKAPFLFVKEAAPHMKERGEGAVVFISSVTA--YFPNEDIGPYCVSKTALLGLTKALSRPLAAMNIRVNNVAPGLIETGFS</Hsp_qseq>
      <Hsp_hseq>LAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPNAKVHVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQIATEDIQDVFDTNVTALINITQAVLPIFQAKNSGDIVNLGSIAGRDAYPTGSI--YCASKFAVGAFTDSLRKELINTKIRVILIAPGLVETEFS</Hsp_hseq>
      <Hsp_midline>LA K  ++TG++ GIG A A     A +G   +++++R  E +    + +  E  N    V    +  A++    I+    +   +DILV NA     +  VG +      +V D N+ A     +   P  + +  G +V + S+     +P   I  YC SK A+   T +L + L    IRV  +APGL+ET FS</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YKR009C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:454352:457054:-1 gene:YKR009C transcript:YKR009C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FOX2 description:3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase; multifunctional enzyme of the peroxisomal fatty acid beta-oxidation pathway; mutation is functionally complemented by human HSD17B4 [Source:SGD;Acc:S000001717]</Hit_def>
  <Hit_accession>YKR009C</Hit_accession>
  <Hit_len>900</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>3.72475e-07</Hsp_evalue>
      <Hsp_query-from>58</Hsp_query-from>
      <Hsp_query-to>594</Hsp_query-to>
      <Hsp_hit-from>7</Hsp_hit-from>
      <Hsp_hit-to>195</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>193</Hsp_align-len>
      <Hsp_qseq>LAGKIAVVTGSTYGIGLAIARRLAQHGAHVVV---------SSRTXXXXXXXXXXXXXXGLNVTGIVCHVGDA--DQRTKLIKETVSKLGGLDILVLNAAV---NPYVGPLLNATAEVLDVNLKAPFLFVKEAAPHMKERGEGAVVFISSVTAYFPNEDIGPYCVSKTALLGLTKALSRPLAAMNIRVNNVAP</Hsp_qseq>
      <Hsp_hseq>FKDRVVVITGAGGGLGKVYALAYASRGAKVVVNDLGGTLGGSGHNSKAADLVVDEIKKAG----GIAVANYDSVNENGEKIIETAIKEFGRVDVLINNAGILRDVSFAKMTEREFASVVDVHLTGGYKLSRAAWPYMRSQKFGRIINTASPAGLFGNFGQANYSAAKMGLVGLAETLAKEGAKYNINVNSIAP</Hsp_hseq>
      <Hsp_midline>   ++ V+TG+  G+G   A   A  GA VVV         S    +      +E+   G    GI     D+  +   K+I+  + + G +D+L+ NA +     +        A V+DV+L   +   + A P+M+ +  G ++  +S    F N     Y  +K  L+GL + L++  A  NI VN++AP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YIR036C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:422074:422865:-1 gene:YIR036C transcript:YIR036C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IRC24 description:Putative benzil reductase;(GFP)-fusion protein localizes to the cytoplasm and is induced by the DNA-damaging agent MMS; sequence similarity with short-chain dehydrogenase/reductases; null mutant has increased spontaneous Rad52p foci [Source:SGD;Acc:S000001475]</Hit_def>
  <Hit_accession>YIR036C</Hit_accession>
  <Hit_len>263</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.8246</Hsp_bit-score>
      <Hsp_score>107</Hsp_score>
      <Hsp_evalue>3.10747e-06</Hsp_evalue>
      <Hsp_query-from>64</Hsp_query-from>
      <Hsp_query-to>636</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>201</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>200</Hsp_align-len>
      <Hsp_qseq>GKIAVVTGSTYGIGLAIARRLAQHGAHVVVSSRTXXXXXXXXXXXXXXGLNVTGIVCHVGDADQRTKLIKETVSKLGGLDILVLNAAVNPYVGPLLNATAE--------VLDVNLKAPFLFVKEAAPHMKERGE-GAVVFISSVTAYFPNEDIGPYCVSKTALLGLTKALSRPLAAMNIRVNNVAPGLIETGFSAGVSDS</Hsp_qseq>
      <Hsp_hseq>GKVILITGASRGIGLQLVKTVIEEDDECIVYGVARTEAGLQSLQREYGADKFVYRVLDITDRSRMEALVEEIRQKHGKLDGIVANAGMLEPVKSISQSNSEHDIKQWERLFDVNFFSIVSLVALCLPLLKSSPFVGNIVFVSSGASVKPYNGWSAYGCSKAALNHFAMDIASEEPSDKVRAVCIAPGVVDTQMQKDIRET</Hsp_hseq>
      <Hsp_midline>GK+ ++TG++ GIGL + + + +     +V           + +           V  + D  +   L++E   K G LD +V NA +   V  +  + +E        + DVN  +    V    P +K     G +VF+SS  +  P      Y  SK AL      ++    +  +R   +APG+++T     + ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>542895678</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055569-RA transcript Note:&quot;Similar to AHCY Adenosylhomocysteinase (Bos taurus)&quot; offset:131 AED:0.06 eAED:0.06 QI:131|0.87|0.77|1|0.87|0.77|9|2695|366</Iteration_query-def>
  <Iteration_query-len>3927</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YER043C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:235770:237119:-1 gene:YER043C transcript:YER043C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAH1 description:S-adenosyl-L-homocysteine hydrolase; catabolizes S-adenosyl-L-homocysteine which is formed after donation of the activated methyl group of S-adenosyl-L-methionine (AdoMet) to an acceptor; regulates cellular lipid homoeostasis by regulating phosphatidylcholine(PC)synthesis and triacylglycerol (TG) levels [Source:SGD;Acc:S000000845]</Hit_def>
  <Hit_accession>YER043C</Hit_accession>
  <Hit_len>449</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>447.973</Hsp_bit-score>
      <Hsp_score>1151</Hsp_score>
      <Hsp_evalue>9.19433e-146</Hsp_evalue>
      <Hsp_query-from>147</Hsp_query-from>
      <Hsp_query-to>1229</Hsp_query-to>
      <Hsp_hit-from>7</Hsp_hit-from>
      <Hsp_hit-to>449</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>247</Hsp_identity>
      <Hsp_positive>292</Hsp_positive>
      <Hsp_gaps>88</Hsp_gaps>
      <Hsp_align-len>446</Hsp_align-len>
      <Hsp_qseq>NYKVADISLAEWGRKALDIAENEMPGLMKMRQMYGKSKPLTGARISGCLHMTVQTAVLIETLVELGAKVMWSSCNIFSTQDHXXXXXXXXGIPVFAWKGETDEEYVWCIEQTLI-FPDGKPLNMILDDGGDLTNLVHTKHPELLKGIRGVSEETTTGVHNLYKMLKNNELKIPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGSAQSLRSFGARLDVKWLN-----DHAAEKINIKPQVDRYRLK-------------NGRHVILLAEGRLVNLGCAMGH----------------------------------------------------PSFVMSNSFTNQVLAQIELWKHTDK--------------YPLGVHFLPKKLDEAVAEAHLHQLGVKLTKLSEDQASYLSIPREGPFKPDHYRY</Hsp_qseq>
      <Hsp_hseq>NYKIADISLAAFGRKEIELAEHEMPGLMAIRKAYGDVQPLKGARIAGCLHMTIQTAVLIETLVALGAEVTWSSCNIYSTQDHAAAAIAASGVPVFAWKGETEEEYLWCIEQQLFAFKDNKKLNLILDDGGDLTTLVHEKHPEMLEDCFGLSEETTTGVHHLYRMVKEGKLKVPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVAVVAGYGDVGKGCAAALRGMGARVLVTEIDPINALQAAMEGYQVVTMEDASHIGQVFVTTTGCRDIINGEHFINMPEDAIV---CNIGHFDIEIDVAWLKANAKECINIKPQVDRYLLSSGRHVILLANGRLVNLGCATGHSSFVMSCSFSNQVLAQIALFKSNDKSFREKHIEFQKTGPFEVGVHVLPKILDEAVAKFHLGNLGVRLTKLSKVQSEYLGIPEEGPFKADHYRY</Hsp_hseq>
      <Hsp_midline>NYK+ADISLA +GRK +++AE+EMPGLM +R+ YG  +PL GARI+GCLHMT+QTAVLIETLV LGA+V WSSCNI+STQDHAAAAIA +G+PVFAWKGET+EEY+WCIEQ L  F D K LN+ILDDGGDLT LVH KHPE+L+   G+SEETTTGVH+LY+M+K  +LK+PAINVNDSVTKSKFDNLYGCRESL+DGIKRATDVM+AGKVAVVAGYGDVGKG A +LR  GAR+ V  ++       A E   +    D   +              NG H I + E  +V   C +GH                                                     SFVMS SF+NQVLAQI L+K  DK              + +GVH LPK LDEAVA+ HL  LGV+LTKLS+ Q+ YL IP EGPFK DHYRY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2714940136</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0055570-RA transcript Note:&quot;Similar to Ist1 IST1 homolog (Rattus norvegicus)&quot; offset:327 AED:0.09 eAED:0.09 QI:327|0.85|1|1|0.57|0.5|8|1854|278</Iteration_query-def>
  <Iteration_query-len>3018</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YNL265C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:144280:145281:-1 gene:YNL265C transcript:YNL265C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IST1 description:Protein with positive role in the multivesicular body sorting pathway; functions and forms a complex with Did2p; recruitment to endosomes is mediated by the Vps2p-Vps24p subcomplex of ESCRT-III; also interacts with Vps4p [Source:SGD;Acc:S000005209]</Hit_def>
  <Hit_accession>YNL265C</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>5.65679e-13</Hsp_evalue>
      <Hsp_query-from>403</Hsp_query-from>
      <Hsp_query-to>858</Hsp_query-to>
      <Hsp_hit-from>27</Hsp_hit-from>
      <Hsp_hit-to>184</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>QKKKTELAQKARKEIADYLGSGKDERARIRVEHIIREDYLVEAMEIXXXXXXXXXARFGLI-------QSMKE-MDPGLEEAISTLIWAAPRLQVEVQELKVVSDQLCAKYSKEYGKLCRTNQTGTVNERLMHKLGVEAPPKMLVERYLIEIAKNYNVAF</Hsp_qseq>
      <Hsp_hseq>QEKQQAIAKQSRRQVAQLLLTNKEQKAHYRVETLIHDDIHIELLEILELYCELLLARVQVINDISTEEQLVKEHMDDGINEAIRSLIYAILFVD-EVKELSQLKDLMAWKINVEFVNGVIADHID-VPEKIIKKCSPSVPKEELVDLYLKEIAKTYDVPY</Hsp_hseq>
      <Hsp_midline>Q+K+  +A+++R+++A  L + K+++A  RVE +I +D  +E +EILEL C+LLLAR  +I       Q +KE MD G+ EAI +LI+A   +  EV+EL  + D +  K + E+      +    V E+++ K     P + LV+ YL EIAK Y+V +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>2050424969</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

