<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0061281-RA transcript Note:&quot;Similar to FBXL4 F-box/LRR-repeat protein 4 (Bos taurus)&quot; offset:0 AED:0.31 eAED:0.38 QI:0|0.28|0.25|0.87|1|1|8|0|560</BlastOutput_query-def>
  <BlastOutput_query-len>1683</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061281-RA transcript Note:&quot;Similar to FBXL4 F-box/LRR-repeat protein 4 (Bos taurus)&quot; offset:0 AED:0.31 eAED:0.38 QI:0|0.28|0.25|0.87|1|1|8|0|560</Iteration_query-def>
  <Iteration_query-len>1683</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1065773222</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0045435-RA transcript Note:&quot;Similar to ZC3H12B Probable ribonuclease ZC3H12B (Homo sapiens)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0|0|3|119|369</Iteration_query-def>
  <Iteration_query-len>1229</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>92</Statistics_hsp-len>
      <Statistics_eff-space>731276839</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061283-RA transcript Note:&quot;Similar to XPO4 Exportin-4 (Homo sapiens)&quot; offset:0 AED:0.30 eAED:0.35 QI:0|0|0|1|1|1|10|0|561</Iteration_query-def>
  <Iteration_query-len>1686</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1068060289</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061284-RA transcript Note:&quot;Similar to xpo4 Exportin-4 (Xenopus laevis)&quot; offset:0 AED:0.43 eAED:0.95 QI:0|0|0|0.62|0.86|0.81|16|0|333</Iteration_query-def>
  <Iteration_query-len>1002</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>566096348</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0046128-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0|0|5|1370|688</Iteration_query-def>
  <Iteration_query-len>3437</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2355500015</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061286-RA transcript Note:&quot;Similar to MAP3K4 Mitogen-activated protein kinase kinase kinase 4 (Homo sapiens)&quot; offset:0 AED:0.46 eAED:0.59 QI:0|0|0|0.31|1|0.93|16|0|538</Iteration_query-def>
  <Iteration_query-len>1617</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>133.65</Hsp_bit-score>
      <Hsp_score>335</Hsp_score>
      <Hsp_evalue>2.26934e-33</Hsp_evalue>
      <Hsp_query-from>994</Hsp_query-from>
      <Hsp_query-to>1572</Hsp_query-to>
      <Hsp_hit-from>1047</Hsp_hit-from>
      <Hsp_hit-to>1305</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>89</Hsp_identity>
      <Hsp_positive>130</Hsp_positive>
      <Hsp_gaps>76</Hsp_gaps>
      <Hsp_align-len>264</Hsp_align-len>
      <Hsp_qseq>KVYTCVNVDTGELMAMKEPNDHKT---------IKETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEEVSRLGL--QEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCS--------------------VKLKNISQTM------------PGEVNSTLGTAAADIWSLGCVLIEMATGKR----------------------------LSPEGRDFLALCLESDPSDRCTASQLL</Hsp_qseq>
      <Hsp_hseq>QVYSAINLENGEILAVKEIKIHDTTTMKKIFPLIKE---EMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEYCEGGSLASLLDHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLG--ADDVWALGCVVLEMATGRRPWSNLDNEWAIMYHVAAGRIPQLPNRDEMTAAGRAFLERCLVQDPTMRATAVELL</Hsp_hseq>
      <Hsp_midline>+VY+ +N++ GE++A+KE   H T         IKE   E+ + E +NH N+V+YYGVE+HR+++ IFMEYC+ G+L  +   G    E V + YT ++   +  LH+ G+VHRDIK  NI L   G IK  DFG +                    V+ K++++ M               V   LG  A D+W+LGCV++EMATG+R                            ++  GR FL  CL  DP+ R TA +LL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>130.183</Hsp_bit-score>
      <Hsp_score>326</Hsp_score>
      <Hsp_evalue>3.2956e-32</Hsp_evalue>
      <Hsp_query-from>994</Hsp_query-from>
      <Hsp_query-to>1572</Hsp_query-to>
      <Hsp_hit-from>1279</Hsp_hit-from>
      <Hsp_hit-to>1553</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>90</Hsp_identity>
      <Hsp_positive>130</Hsp_positive>
      <Hsp_gaps>82</Hsp_gaps>
      <Hsp_align-len>275</Hsp_align-len>
      <Hsp_qseq>KVYTCVNVDTGELMAMKEPN--DHKTIKET----ADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEEVSRLGL--QEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKN-------------------------ISQTMPGEVNSTL---GT------------------AAADIWSLGCVLIEMATGKR----------------------------LSPEGRDFLALCLESDPSDRCTASQLL</Hsp_qseq>
      <Hsp_hseq>RVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAALLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPWANLDNEWAIMYHVAAGHTPQFPTKDEVSSAGMKFLERCLIQNPSKRASAVELL</Hsp_hseq>
      <Hsp_midline>+VY+ V++D GE++A+KE N  D K++++      +E+ + E +NH N+V YYGVE+HR+++ IFMEYC+ G+L  +   G    E V + YT Q+   +  LHE GIVHRD+K  NI L   G IK  DFG + K+ N                          S+ +    N+ L   GT                   A D+WSLGCV++EM TG+R                            +S  G  FL  CL  +PS R +A +LL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>127.872</Hsp_bit-score>
      <Hsp_score>320</Hsp_score>
      <Hsp_evalue>2.0242e-31</Hsp_evalue>
      <Hsp_query-from>997</Hsp_query-from>
      <Hsp_query-to>1593</Hsp_query-to>
      <Hsp_hit-from>1189</Hsp_hit-from>
      <Hsp_hit-to>1442</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>84</Hsp_identity>
      <Hsp_positive>124</Hsp_positive>
      <Hsp_gaps>55</Hsp_gaps>
      <Hsp_align-len>254</Hsp_align-len>
      <Hsp_qseq>VYTCVNVDTGELMAMKEPNDHK----------TIKETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEEVSRL--GLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNI----SQTM--------PGEVNSTLG-TAAADIWSLGCVLIEMATGKR------------------------------LSPEGRDFLALCLESDPSDRCTASQLLDHAFVKV</Hsp_qseq>
      <Hsp_hseq>VYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANELLSHPFSEV</Hsp_hseq>
      <Hsp_midline>VY C+NV TGE+MA+K+    K          T++    E+   + ++H N+V+Y G E       +F+EY   G++  + R+     EP+I+H T Q+   +  LH +GI+HRD+K  N+ L   G  K+ DFG S K K+I      TM        P  V++  G +A  DIWSLGC+++EM  GKR                              +S  GR+FL  C E +P  R TA++LL H F +V</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>121.709</Hsp_bit-score>
      <Hsp_score>304</Hsp_score>
      <Hsp_evalue>1.57458e-29</Hsp_evalue>
      <Hsp_query-from>997</Hsp_query-from>
      <Hsp_query-to>1587</Hsp_query-to>
      <Hsp_hit-from>39</Hsp_hit-from>
      <Hsp_hit-to>272</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>114</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>235</Hsp_align-len>
      <Hsp_qseq>VYTCVNVDTGELMAMKE---PNDHKTIKETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEEV---SRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQTMPGEVN----STLGTAAA----DIWSLGCVLIEMATGK------------------------RLSPEGRDFLALCLESDPSDRCTASQLLDHAFV</Hsp_qseq>
      <Hsp_hseq>VYKAINKHTDQVVAIKEVVYENDEE-LNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSALTLAGTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNPPYHNLTDANIYYAVENDTYYPPSSFSEPLKDFLSKCFVKNMYKRPTADQLLKHVWI</Hsp_hseq>
      <Hsp_midline>VY  +N  T +++A+KE    ND + + +   EI + + +NH+N+V+Y+G      E+YI +EYC  G+L  +   S  GL E   + Y  Q    +  LH  G++HRDIK ANI L++   +KL DFG S  + + + T+ G +N      LG   A    DIWSLG  ++EM T                            S   +DFL+ C   +   R TA QLL H ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>114.39</Hsp_bit-score>
      <Hsp_score>285</Hsp_score>
      <Hsp_evalue>3.214e-27</Hsp_evalue>
      <Hsp_query-from>1060</Hsp_query-from>
      <Hsp_query-to>1587</Hsp_query-to>
      <Hsp_hit-from>496</Hsp_hit-from>
      <Hsp_hit-to>712</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>217</Hsp_align-len>
      <Hsp_qseq>KTIKETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEE-VSRLG-LQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQTM--------------PGEVNSTLGTAAADIWSLGCVLIEMATGKRLSP-------------------------EGRDFLALCLESDPSDRCTASQLLDHAFV</Hsp_qseq>
      <Hsp_hseq>KMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKIGTNTTPEIPSWATSEGKNFLRKAFELDYQYRPSALELLQHPWL</Hsp_hseq>
      <Hsp_midline>K +     E+ + + ++H N+V YYG       + IF+EY   G++   ++  G  +E +I ++T+QI   +  LH++ I+HRDIKGANI +   G +K+ DFG S KL  +++                P  V  T  TA ADIWS GCV+IEM TGK   P                         EG++FL    E D   R +A +LL H ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>114.005</Hsp_bit-score>
      <Hsp_score>284</Hsp_score>
      <Hsp_evalue>4.97714e-27</Hsp_evalue>
      <Hsp_query-from>859</Hsp_query-from>
      <Hsp_query-to>1593</Hsp_query-to>
      <Hsp_hit-from>4</Hsp_hit-from>
      <Hsp_hit-to>278</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>131</Hsp_positive>
      <Hsp_gaps>56</Hsp_gaps>
      <Hsp_align-len>288</Hsp_align-len>
      <Hsp_qseq>RMERVRKAMARFEQKLDAQSQRRRVVGRVCSTPHAINNLMHVGLRKVYTCVNVDTGELMAMKEPN---DHKTIKETADEIKIFEGINH-SNLVRYYGVELHREEMYIFMEYCDEGTLEEVSRLG-LQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNIS---QTMPGE---------VNSTLGTAAADIWSLGCVLIEMATG--------------------------KRLSPEGRDFLALCLESDPSDRCTASQLLDHAFVKV</Hsp_qseq>
      <Hsp_hseq>KPQNSKQGLAEGEMDVSSLFKRTEVIGR-----------GKFGV--VYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLRPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIKSKPPRLEDRSYSTSLKEFIALCLDEDPKERLSADDLLKSKFIRA</Hsp_hseq>
      <Hsp_midline>+ +  ++ +A  E  + +  +R  V+GR              G+  VY   NV TG + A+K  N   D   +++   EI+    +   SN+ RYYG  L    ++I ME+C  G+L  + R G + E  I    +++  A+  +H+  ++HRDIK AN+ +T+ G++KL DFG + ++   S   QTM G          +         DIWSLG    E+ATG                          +  S   ++F+ALCL+ DP +R +A  LL   F++ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>106.686</Hsp_bit-score>
      <Hsp_score>265</Hsp_score>
      <Hsp_evalue>8.96758e-25</Hsp_evalue>
      <Hsp_query-from>910</Hsp_query-from>
      <Hsp_query-to>1590</Hsp_query-to>
      <Hsp_hit-from>56</Hsp_hit-from>
      <Hsp_hit-to>338</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>130</Hsp_positive>
      <Hsp_gaps>58</Hsp_gaps>
      <Hsp_align-len>284</Hsp_align-len>
      <Hsp_qseq>AQSQRRRVVGRVCSTP-----------HAINNLMHVGLRKVYTCVNVDTGELMAMK-----EPNDHKTIKETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEEV--SRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQ---TMPGEVNST-----LGTAAA-----DIWSLGCVLIEMATG--------------------------KRLSPEGRDFLALCLESDPSDRCTASQLLDHAFVK</Hsp_qseq>
      <Hsp_hseq>AQKKKREKLSALCKTPPSLIKTRGKDYHRGHFLGEGGFARCFQ-IKDDSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRDKPISDEGKILIRDILSLDPIERPSLTEIMDYVWFR</Hsp_hseq>
      <Hsp_midline>AQ ++R  +  +C TP           H  + L   G  + +  +  D+GE+ A K          KT K+   EI+I + ++H N+V++         +YI +E C  G+L E+   R  L EP +R +T QIC AI  +H R ++HRD+K  NIF  S  ++K+GDFG +  L N S+   T+ G  N       +G  +      DIWSLG +L  +  G                          K +S EG+  +   L  DP +R + ++++D+ + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>92.8189</Hsp_bit-score>
      <Hsp_score>229</Hsp_score>
      <Hsp_evalue>2.79651e-20</Hsp_evalue>
      <Hsp_query-from>970</Hsp_query-from>
      <Hsp_query-to>1587</Hsp_query-to>
      <Hsp_hit-from>622</Hsp_hit-from>
      <Hsp_hit-to>871</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>250</Hsp_align-len>
      <Hsp_qseq>NLMHVGLRK---VYTCVNVDTGELMAMKEPNDHKTIKE--TADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEEV-SRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLK--NISQTM---------PGEVNSTLGTAAADIWSLGCVLIEMATG---------------------------KRLSPEGRDFLALCLESDPSDRCTASQLLDHAFV</Hsp_qseq>
      <Hsp_hseq>NLVKIGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKELIINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVTHCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPPYLNETPLRALYLIATNGTPKLKEPENLSSSLKKFLDWCLCVEPEDRASATELLHDEYI</Hsp_hseq>
      <Hsp_midline>NL+ +G      VYT   + T   +A+K+ N  K  K+    +EI + +G  H N+V +    + + ++++ MEY + G+L +V +   L E  I    ++  + +  LH +G++HRDIK  NI L+  G IKL DFG   ++   N+ +T          P  V+        DIWSLG ++IEM  G                           + LS   + FL  CL  +P DR +A++LL   ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.9669</Hsp_bit-score>
      <Hsp_score>219</Hsp_score>
      <Hsp_evalue>5.72387e-20</Hsp_evalue>
      <Hsp_query-from>997</Hsp_query-from>
      <Hsp_query-to>1512</Hsp_query-to>
      <Hsp_hit-from>21</Hsp_hit-from>
      <Hsp_hit-to>214</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>196</Hsp_align-len>
      <Hsp_qseq>VYTCVNVDTGELMAMKE---PNDHKTIKETADEIKIFEGINHSNLVRYYGVELHREE----MYIFME-----YCDEGTLEEVSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQTMPGEV------------NSTLGTAAADIWSLGCVLIEMATGKRLSPEGRD</Hsp_qseq>
      <Hsp_hseq>VYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHENIVRLYDV-IHTENKLTLVFEFMDNDLKKYMDSRTVGNTPR-GLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTND</Hsp_hseq>
      <Hsp_midline>VY  +N  TG  +A+KE    ++  T      EI + + + H N+VR Y V +H E     ++ FM+     Y D  T+    R GL+  +++++  Q+   +   HE  I+HRD+K  N+ +   G +KLGDFG +        T   EV             S   + + DIWS GC+L EM TGK L P   D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.8929</Hsp_bit-score>
      <Hsp_score>224</Hsp_score>
      <Hsp_evalue>6.79779e-20</Hsp_evalue>
      <Hsp_query-from>997</Hsp_query-from>
      <Hsp_query-to>1590</Hsp_query-to>
      <Hsp_hit-from>32</Hsp_hit-from>
      <Hsp_hit-to>273</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>66</Hsp_gaps>
      <Hsp_align-len>253</Hsp_align-len>
      <Hsp_qseq>VYTCVNVDTGELMAMKEPN---DHKTIKETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEEVSRL----GLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQTMPGEVNSTL------GTA-----------------AADIWSLGCVLIEMATG-----------------KRLSPE--------GRDFLALCLESDPSDRCTASQLLDHAFVK</Hsp_qseq>
      <Hsp_hseq>VYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVS-----------GHIRSTLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPPLSKYDPMKVMTNLPKRKPPKLQGPFSDAAKDFVAGCLVKTPADRPSAYNLLSFEFVK</Hsp_hseq>
      <Hsp_midline>VY  V+  T E++A+K  N     + I+  A EI     +    +  Y    L    M+I MEYC  G+  ++ +     GL E  +     ++   +  LHE+  +HRDIK ANI L   G +KLGDFG S           G + STL      GT                   ADIWSLG    E+  G                 KR  P+         +DF+A CL   P+DR +A  LL   FVK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.9669</Hsp_bit-score>
      <Hsp_score>219</Hsp_score>
      <Hsp_evalue>1.29014e-19</Hsp_evalue>
      <Hsp_query-from>1021</Hsp_query-from>
      <Hsp_query-to>1485</Hsp_query-to>
      <Hsp_hit-from>110</Hsp_hit-from>
      <Hsp_hit-to>279</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>170</Hsp_align-len>
      <Hsp_qseq>TGELMAMKEPNDH-----KTIKETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEEVSRLG--LQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQTM--------PGEVNSTLGTAAADIWSLGCVLIEMATG</Hsp_qseq>
      <Hsp_hseq>NGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAG</Hsp_hseq>
      <Hsp_midline> G   A+K    H     K ++ T DE ++   ++H  ++R +G     +++++ M+Y + G L  + R       PV + Y  ++C A+  LH + I++RD+K  NI L   GHIK+ DFG +  + +++ T+        P  V++     + D WS G ++ EM  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.8853</Hsp_bit-score>
      <Hsp_score>211</Hsp_score>
      <Hsp_evalue>1.69277e-18</Hsp_evalue>
      <Hsp_query-from>1060</Hsp_query-from>
      <Hsp_query-to>1485</Hsp_query-to>
      <Hsp_hit-from>127</Hsp_hit-from>
      <Hsp_hit-to>278</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>152</Hsp_align-len>
      <Hsp_qseq>KTIKETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEEVSRLG--LQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQTM--------PGEVNSTLGTAAADIWSLGCVLIEMATG</Hsp_qseq>
      <Hsp_hseq>KQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAG</Hsp_hseq>
      <Hsp_midline>K ++ T DE  +   + H  ++R +G     +++++ M+Y + G L  + R       PV + Y  ++C A+  LH + I++RD+K  NI L   GHIK+ DFG +  + +++ T+        P  V++     + D WS G ++ EM  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.1149</Hsp_bit-score>
      <Hsp_score>209</Hsp_score>
      <Hsp_evalue>2.54181e-18</Hsp_evalue>
      <Hsp_query-from>904</Hsp_query-from>
      <Hsp_query-to>1485</Hsp_query-to>
      <Hsp_hit-from>50</Hsp_hit-from>
      <Hsp_hit-to>261</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>212</Hsp_align-len>
      <Hsp_qseq>LDAQSQRRRVVGRVCSTPHAINNLMHVG---LRKVYTCVNVDTGELMAMKEPNDHKTIK-----ETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEEVSRLG--LQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQTM--------PGEVNSTLGTAAADIWSLGCVLIEMATG</Hsp_qseq>
      <Hsp_hseq>LTSQLPQKSLVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAG</Hsp_hseq>
      <Hsp_midline>L +Q  ++ +V +   T H    +  +G     +V+   +V  G   A+K     + +K      T DE ++ + + H  L+R +G       +++ M+Y + G L  + R       PV + Y  ++  A+  LH   I++RD+K  NI L   GHIK+ DFG + +++ ++ T+        P  + +     + D WSLG ++ EM  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.8853</Hsp_bit-score>
      <Hsp_score>211</Hsp_score>
      <Hsp_evalue>3.91561e-18</Hsp_evalue>
      <Hsp_query-from>964</Hsp_query-from>
      <Hsp_query-to>1608</Hsp_query-to>
      <Hsp_hit-from>363</Hsp_hit-from>
      <Hsp_hit-to>630</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>53</Hsp_gaps>
      <Hsp_align-len>268</Hsp_align-len>
      <Hsp_qseq>INNLMHVGLRKVYTCVNVDTGELMAMKEPN---DHKTIKETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEEV----SRL-GLQEPVIRHYTKQICTAITELHER-GIVHRDIKGANIFLTST-GHIKLGDFGCSVKL------KNI---SQTMPGEVNS-----TLGTAAADIWSLGCVLIEMATGK-----------------------------RLSPEGRDFLALCLESDPSDRCTASQLLDHAFVKVCLDQD</Hsp_qseq>
      <Hsp_hseq>LDELGHGNYGNVSKVLHKPTNVIMATKEVRLELDEAKFRQILMELEVLHKCNSPYIVDFYGAFFIEGAVYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSANQGTVKLCDFGVSGNLVASLAKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYPPETYDNIFSQLSAIVDGPPPRLPSDKFSSDAQDFVSLCLQKIPERRPTYAALTEHPWLVKYRNQD</Hsp_hseq>
      <Hsp_midline>++ L H     V   ++  T  +MA KE     D    ++   E+++    N   +V +YG       +Y+ MEY D G+L+++    S + G+ EP +      +   + EL E+  I+HRD+K  NI  ++  G +KL DFG S  L       NI   S   P  + S        T  +DIWSLG  ++EMA G+                             + S + +DF++LCL+  P  R T + L +H ++    +QD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.5741</Hsp_bit-score>
      <Hsp_score>205</Hsp_score>
      <Hsp_evalue>7.10163e-18</Hsp_evalue>
      <Hsp_query-from>997</Hsp_query-from>
      <Hsp_query-to>1587</Hsp_query-to>
      <Hsp_hit-from>118</Hsp_hit-from>
      <Hsp_hit-to>355</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>238</Hsp_align-len>
      <Hsp_qseq>VYTCVNVDTGELMAMKEPNDHKTIKETAD-----EIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEEVSRL--GLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSV------KLKNISQTM----PGEVNSTLGTAAADIWSLGCVLIEMATG-------------KR-----------LSPEGRDFLALCLESDPSDRCTASQLLDHAFV</Hsp_qseq>
      <Hsp_hseq>VYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMPSNISQDAQDLILKLLKYDPKDRMRLGDVKMHPWI</Hsp_hseq>
      <Hsp_midline>VY   +  TG + A+K     + IK         E++I   +NH NL + YG     + +Y+ MEY   G + ++ RL     + +   Y  QI  A+  +H++ I+HRDIK  NI +     IKL DFG S+      + K +  T+    P  V S       D W+LG +  E+ TG             KR           +S + +D +   L+ DP DR     +  H ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.8037</Hsp_bit-score>
      <Hsp_score>203</Hsp_score>
      <Hsp_evalue>3.01104e-17</Hsp_evalue>
      <Hsp_query-from>997</Hsp_query-from>
      <Hsp_query-to>1590</Hsp_query-to>
      <Hsp_hit-from>235</Hsp_hit-from>
      <Hsp_hit-to>489</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>57</Hsp_gaps>
      <Hsp_align-len>255</Hsp_align-len>
      <Hsp_qseq>VYTCVNVDTGELMAMKEPN----DHKTIKETADEIKIFEGINHSNLVRYYGVELHREE--MYIFMEYCDEGTLEEVSRLGLQ------EPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQT---------MPGEVNSTLGTAAADIWSLGCVLIEMATGK----------------------RLSPEGRD--------------FLALCLESDPSDRCTASQLLDHAFVK</Hsp_qseq>
      <Hsp_hseq>VSKCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQFNRSFQSEYIVRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVSGEAVNSLATTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANGKFPCSSEKMAANIAPFELLMWILTFTPELKDEPESNIIWSPSFKSFIDYCLKKDSRERPSPRQMINHPWIK</Hsp_hseq>
      <Hsp_midline>V  C   +  ++ A+K  N    D +  K+   E++         +VRYYG+    E   +YI MEY    +L+ + +  L+      E V+    + +   ++ LHE+ ++HRDIK  NI L   G +KL DFG S +  N   T          P  +     +  +D+WSLG  ++E+A GK                        +PE +D              F+  CL+ D  +R +  Q+++H ++K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.0333</Hsp_bit-score>
      <Hsp_score>201</Hsp_score>
      <Hsp_evalue>4.58773e-17</Hsp_evalue>
      <Hsp_query-from>997</Hsp_query-from>
      <Hsp_query-to>1611</Hsp_query-to>
      <Hsp_hit-from>205</Hsp_hit-from>
      <Hsp_hit-to>451</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>249</Hsp_align-len>
      <Hsp_qseq>VYTCVNVDTGELMAMK----EPNDHKTIKETADEIKIFEGIN-HSNLVRYYGVELHR---EEMYIFMEYCDEGTLEEV---------------SRLGLQEPVIRHYTKQICTAITELH-ERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKN-ISQTM--------PGEVNSTLGTAAADIWSLGCVLIEMATGK------RLSPEG-RDFLALCLESD----PSDRCTASQLLDHAFVKVCLDQDE</Hsp_qseq>
      <Hsp_hseq>VVKALHVPDSKIVAKKTIPVEQNNSTIINQLVRELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKLINSIADTFVGTSTYMSPERIQGNVYSIKGDVWSLGLMIIELVTGEFPLGGHNDTPDGILDLLQRIVNEPSPRLPKDRIYSKEMTD--FVNRCCIKNE</Hsp_hseq>
      <Hsp_midline>V   ++V   +++A K    E N+   I +   E+ I + +  H N++ +YG   ++    E+ I MEY D G+L+++                +    E  I      +   +  L+ +  I+HRDIK +N+ + S G IKL DFG S KL N I+ T         P  +   + +   D+WSLG ++IE+ TG+        +P+G  D L   +       P DR  + ++ D  FV  C  ++E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.2629</Hsp_bit-score>
      <Hsp_score>199</Hsp_score>
      <Hsp_evalue>1.48165e-16</Hsp_evalue>
      <Hsp_query-from>997</Hsp_query-from>
      <Hsp_query-to>1488</Hsp_query-to>
      <Hsp_hit-from>193</Hsp_hit-from>
      <Hsp_hit-to>386</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>194</Hsp_align-len>
      <Hsp_qseq>VYTCVNVDTGELMAMKEPND-----HKTIKETADEIKIFEGINHS-NLVRYYGVELHREEMYIFMEYCDEGT-LEEVSRLG-LQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQTM----------------------PGEVNSTLGTAAADIWSLGCVLIEMATGK</Hsp_qseq>
      <Hsp_hseq>VMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGK</Hsp_hseq>
      <Hsp_midline>V    ++DT +  A K  N       K +K  + E    + +N+S ++VR +        +Y  +EY   G  L  + + G L E   R+Y  QI  AI  LH  GI+HRDIK  NI L     IKL DFG +  L   + ++                      P  +N +      DIW+ GC+L +M  GK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.337</Hsp_bit-score>
      <Hsp_score>194</Hsp_score>
      <Hsp_evalue>3.54799e-16</Hsp_evalue>
      <Hsp_query-from>1027</Hsp_query-from>
      <Hsp_query-to>1587</Hsp_query-to>
      <Hsp_hit-from>238</Hsp_hit-from>
      <Hsp_hit-to>481</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>57</Hsp_gaps>
      <Hsp_align-len>244</Hsp_align-len>
      <Hsp_qseq>ELMAMKEPN----DHKTIKETADEIKIFEGINHSNLVRYYGV--ELHREEMYIFMEYCDEGTLEEVSRLGLQ------EPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKN-ISQTM--------PGEVNSTLGTAAADIWSLGCVLIEMATGK----------------------RLSPEGRD--------------FLALCLESDPSDRCTASQLLDHAFV</Hsp_qseq>
      <Hsp_hseq>KVFALKTINTMNTDPEYQKQIFRELQFNKSFKSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFGVSGEAVNSLAMTFTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRFPFESDKITQNVAPIELLTMILTFSPQLKDEPELDISWSKTFRSFIDYCLKKDARERPSPRQMLKHPWI</Hsp_hseq>
      <Hsp_midline>++ A+K  N    D +  K+   E++  +      +V+YYG+  +     +YI MEY    +LE   +  L+      E VI    + +   ++ LHER ++HRDIK  NI L   G IKL DFG S +  N ++ T         P  +     +   D+WSLG  L+E+A G+                        SP+ +D              F+  CL+ D  +R +  Q+L H ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.337</Hsp_bit-score>
      <Hsp_score>194</Hsp_score>
      <Hsp_evalue>5.2523e-16</Hsp_evalue>
      <Hsp_query-from>1081</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>609</Hsp_hit-from>
      <Hsp_hit-to>834</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>226</Hsp_align-len>
      <Hsp_qseq>DEIKIFEGINHSNLVRYYGVELHREE-MYIFMEYCDEGTLEEV---------SRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQTMPGEVNSTLGTAA-----------ADIWSLGCVLIEMATG---------------------------KRLSPEGRDFLALCLESDPSDRCTASQLLDHAFVKVCLDQDEI</Hsp_qseq>
      <Hsp_hseq>NEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATNGTPKLKHPESLSLEIKRFLSVCLCVDVRYRASTEELLHHGFFNMACDPKDL</Hsp_hseq>
      <Hsp_midline>+EI + +   H N+V +    L  ++ +++ ME+ + G+L ++         S   L EP I +  ++ C  +  LH++ I+HRDIK  N+ L +   +K+ DFG   +L +        V +    A             D+WSLG + IEM  G                           + LS E + FL++CL  D   R +  +LL H F  +  D  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.9518</Hsp_bit-score>
      <Hsp_score>193</Hsp_score>
      <Hsp_evalue>7.59734e-16</Hsp_evalue>
      <Hsp_query-from>1021</Hsp_query-from>
      <Hsp_query-to>1593</Hsp_query-to>
      <Hsp_hit-from>220</Hsp_hit-from>
      <Hsp_hit-to>468</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>58</Hsp_gaps>
      <Hsp_align-len>249</Hsp_align-len>
      <Hsp_qseq>TGELMAMKEPNDHKTIKE---TADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEE--VSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGH--IKLGDFGCSVKLKNIS--------------QTMPGEVNSTLG---------TAAADIWSLGCVLIEMATGK----------------------------RLSPEGRDFLALCLESDPSDRCTASQLLDHAFVKV</Hsp_qseq>
      <Hsp_hseq>TGKTFAVKIISKRKVIGNMDGVTRELEVLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGPLKDFRISEEARDFIDSLLQVDPNNRSTAAKALNHPWIKM</Hsp_hseq>
      <Hsp_midline>TG+  A+K  +  K I        E+++ + +NH  +VR  G     E  Y+ ME+   G L +   +   + E   R  ++QI TAI  +H  GI HRD+K  NI +       +K+ DFG +    N S              + + G+  S            ++  D+WS+GC++  + TG                             R+S E RDF+   L+ DP++R TA++ L+H ++K+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.0258</Hsp_bit-score>
      <Hsp_score>188</Hsp_score>
      <Hsp_evalue>2.5362e-15</Hsp_evalue>
      <Hsp_query-from>1081</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>421</Hsp_hit-from>
      <Hsp_hit-to>648</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>228</Hsp_align-len>
      <Hsp_qseq>DEIKIFEGINHSNLVRYY-GVELHREEMYIFMEYCDEGTLEEV------SRLG-----LQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKL---KNISQTM--------PGEVNSTLGTAAADIWSLGCVLIEMATG---------------------------KRLSPEGRDFLALCLESDPSDRCTASQLLDHAFVKVCLDQDEI</Hsp_qseq>
      <Hsp_hseq>NELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANNGSPKLRHPESVSKQTKQFLDACLQVNVESRASVRKLLTFEFLSMACSPEQL</Hsp_hseq>
      <Hsp_midline>+E+ +       N+V +     +  EE+++ MEY + G L ++      S  G     L E  + +  K+ C  +  LH + I+HRDIK  NI L S G +K+ DFG  V+L   ++   TM        P  VN        D+WSLG +LIEM  G                           + +S + + FL  CL+ +   R +  +LL   F+ +    +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.2554</Hsp_bit-score>
      <Hsp_score>186</Hsp_score>
      <Hsp_evalue>4.70621e-15</Hsp_evalue>
      <Hsp_query-from>1159</Hsp_query-from>
      <Hsp_query-to>1584</Hsp_query-to>
      <Hsp_hit-from>199</Hsp_hit-from>
      <Hsp_hit-to>390</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>192</Hsp_align-len>
      <Hsp_qseq>MYIFMEYCDEGT-LEEVSRLG-LQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKL----KNISQTMP-----GEVNSTLGTAAA---------------DIWSLGCVLIEMATGKRLSPEGRDFLAL------------------------CLESDPSDRCTASQLLDHAF</Hsp_qseq>
      <Hsp_hseq>LYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKIQYAFTAGFPQIVKDLVKKLLVRDPNDRLTIKQIKAHLF</Hsp_hseq>
      <Hsp_midline>+Y  +EY   G  L  + + G L E   R+Y  QI  A+  LH  GI+HRDIK  NI L     +KL DFG +  L     N +   P      +  S +GTA                 DIW+ GC+L +M  GK       ++L                           L  DP+DR T  Q+  H F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.8702</Hsp_bit-score>
      <Hsp_score>185</Hsp_score>
      <Hsp_evalue>7.25125e-15</Hsp_evalue>
      <Hsp_query-from>1084</Hsp_query-from>
      <Hsp_query-to>1590</Hsp_query-to>
      <Hsp_hit-from>164</Hsp_hit-from>
      <Hsp_hit-to>370</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>207</Hsp_align-len>
      <Hsp_qseq>EIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEE--VSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTG-HIKLGDFGCSV-----KLKNISQTMPGEVNSTL------GTAAADIWSLGCVLIEMATG------------------------KRLSPEGRDFLALCLESDPSDRCTASQLLDHAFVK</Hsp_qseq>
      <Hsp_hseq>EIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMPSNLSSEARDLISKILVIDPEKRITTQEILKHPLIK</Hsp_hseq>
      <Hsp_midline>EI I + I+H+N++  + V  ++ E+Y+ +EY D G L +  VS+  L E    HY KQI   ++  H   I HRD+K  N+ L      IK+ DFG +      KL   S   P   +  +          +D+WS G VL  + TG                          LS E RD ++  L  DP  R T  ++L H  +K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.485</Hsp_bit-score>
      <Hsp_score>184</Hsp_score>
      <Hsp_evalue>1.04883e-14</Hsp_evalue>
      <Hsp_query-from>1084</Hsp_query-from>
      <Hsp_query-to>1590</Hsp_query-to>
      <Hsp_hit-from>81</Hsp_hit-from>
      <Hsp_hit-to>290</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>210</Hsp_align-len>
      <Hsp_qseq>EIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEE--VSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSV-----KLKNISQTMPGEVNSTLGTA------AADIWSLGCVLIEMATGK----------------------------RLSPEGRDFLALCLESDPSDRCTASQLLDHAFVK</Hsp_qseq>
      <Hsp_hseq>EIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERRIKTRDILKHPLLQ</Hsp_hseq>
      <Hsp_midline>EI I + +NH N++R Y V     ++Y+ +EY ++G L    V R  L E     + +QI   ++  H  GIVHRD+K  N+ L    +IK+ DFG +      KL   S   P      + +       A+D+WS G +L  + TG+                             +S E +D +   L  DP  R     +L H  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.3294</Hsp_bit-score>
      <Hsp_score>181</Hsp_score>
      <Hsp_evalue>1.49765e-14</Hsp_evalue>
      <Hsp_query-from>1111</Hsp_query-from>
      <Hsp_query-to>1539</Hsp_query-to>
      <Hsp_hit-from>75</Hsp_hit-from>
      <Hsp_hit-to>239</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>166</Hsp_align-len>
      <Hsp_qseq>HSNLVRYYGVELHREEMYIFMEYCDEGTLEEV--SRLGLQEPVIRHYTKQICTAITELH-ERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQTM--------------PGEVNSTLGTAA--ADIWSLGCVLIEMATGKR----LSPEGRDFLALCLESD</Hsp_qseq>
      <Hsp_hseq>HPNVLRLIDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQTPWELPSLENEDFV-FFIEND</Hsp_hseq>
      <Hsp_midline>H N++R     + +E M+I +E  D G L +     +G+   V + Y +Q+ +AI  LH E G+ HRDIK  NI L   G++KL DFG + + +    T+              P  + S  G  A   DIWS+G +L  + TG+      S E  DF+   +E+D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.559</Hsp_bit-score>
      <Hsp_score>179</Hsp_score>
      <Hsp_evalue>3.92482e-14</Hsp_evalue>
      <Hsp_query-from>1117</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>770</Hsp_hit-from>
      <Hsp_hit-to>989</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>56</Hsp_gaps>
      <Hsp_align-len>221</Hsp_align-len>
      <Hsp_qseq>NLVRYYGVELHREEMYIFMEYCDEGTLEEV---SRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVK-------LKNISQTMPG---EVNSTLGTA----------------AADIWSLGCVLIEM----ATG-------KRL-------SPEGRD--------FLALCLESDPSDRCTASQLLDHAFVKVCLDQDEI</Hsp_qseq>
      <Hsp_hseq>NFVKPMTAVKKKSTLFIQMEYCENRTLYDLIHSENLNQQRDEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNVKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVLDGTGHYNEKIDMYSLGIIFFEMIYPFSTGMERVNILKKLRSVSIEFPPDFDDNKMKVEKKIIRLLIDHDPNKRPGARTLLNSGWLPVK-HQDEV</Hsp_hseq>
      <Hsp_midline>N V+       +  ++I MEYC+  TL ++     L  Q        +QI  A++ +H +GI+HRD+K  NIF+  + ++K+GDFG +         LK  SQ +PG    + S +GTA                  D++SLG +  EM    +TG       K+L        P+  D         + L ++ DP+ R  A  LL+  ++ V   QDE+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.7886</Hsp_bit-score>
      <Hsp_score>177</Hsp_score>
      <Hsp_evalue>4.34919e-14</Hsp_evalue>
      <Hsp_query-from>973</Hsp_query-from>
      <Hsp_query-to>1476</Hsp_query-to>
      <Hsp_hit-from>186</Hsp_hit-from>
      <Hsp_hit-to>374</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>196</Hsp_align-len>
      <Hsp_qseq>LMHVG---LRKVYTCVNVDTGELMAMKE---PNDHKTIKETA-DEIKIFEGINHSNL--VRYYGVELHREEMYIFMEYCDEGTLEEVSRLGLQEPV------IRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQTM---------PGEVNSTLGTAA----ADIWSLGCVLIEM</Hsp_qseq>
      <Hsp_hseq>IMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNVSTIKEIMVE-SQKTVYMIFEYADN----DLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKMNSRADYTNRVITLWYRPPEL--LLGTTNYGTEVDMWGCGCLLVEL</Hsp_hseq>
      <Hsp_midline>+M VG     KVY   N +T +L+A+K+     + +    T+  EIK+ +  +H N+  ++   VE  ++ +Y+  EY D     ++S L L + V       +H  KQ+   +  LH+  I+HRD+KG+NI + + G++K+ DFG + K+ + +            P E+   LGT       D+W  GC+L+E+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.7886</Hsp_bit-score>
      <Hsp_score>177</Hsp_score>
      <Hsp_evalue>5.75891e-14</Hsp_evalue>
      <Hsp_query-from>994</Hsp_query-from>
      <Hsp_query-to>1485</Hsp_query-to>
      <Hsp_hit-from>337</Hsp_hit-from>
      <Hsp_hit-to>538</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>202</Hsp_align-len>
      <Hsp_qseq>KVYTCVNVDTGELMAMKEPNDH-----KTIKETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEG----TLEEVSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQ-TMPGE-------------VNSTLG---------------TAAADIWSLGCVLIEMATG</Hsp_qseq>
      <Hsp_hseq>KVYLVRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFG</Hsp_hseq>
      <Hsp_midline>KVY     DT ++ A+K  N H     K IK    E +I    +H  +V  Y     ++ +Y+ MEYC  G     L+      + E   + Y  ++  A+  LH  G ++RD+K  NI L  +GH+ L DF  S++     + TM                 NS +G               TAA D W+LG ++ EM  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>1.48927e-13</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1533</Hsp_query-to>
      <Hsp_hit-from>120</Hsp_hit-from>
      <Hsp_hit-to>240</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>122</Hsp_align-len>
      <Hsp_qseq>IRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFG---CSVKLKNISQTMPGEVNSTLG----------------TAAADIWSLGCVLIEMATGKRLSPEGRDF---LALCLE</Hsp_qseq>
      <Hsp_hseq>VQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFP-GRDYHHQLWLILE</Hsp_hseq>
      <Hsp_midline>++++T QI  A+  +H   ++HRDIK +N+ L S   +K+ DFG   C     +  +T+ G +   +                 T A DIWS GC+L EM +GK L P GRD+   L L LE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.8626</Hsp_bit-score>
      <Hsp_score>172</Hsp_score>
      <Hsp_evalue>1.70105e-13</Hsp_evalue>
      <Hsp_query-from>1060</Hsp_query-from>
      <Hsp_query-to>1488</Hsp_query-to>
      <Hsp_hit-from>194</Hsp_hit-from>
      <Hsp_hit-to>359</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>166</Hsp_align-len>
      <Hsp_qseq>KTIKETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTL-EEVSRLG-LQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKN---ISQTMPGEVNS---------------TLGTAAA---DIWSLGCVLIEMATGK</Hsp_qseq>
      <Hsp_hseq>KRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGK</Hsp_hseq>
      <Hsp_midline>K ++ T  E  I   I H N+V+ +       ++Y+ ++Y   G L   +   G L E  +  Y  +I  A+  LH +G+V+RD+K  N  L   GH+ L DFG S K  N   + +  P  VN+                LG A +   D +SLGC+L +M  GK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>1.79588e-12</Hsp_evalue>
      <Hsp_query-from>997</Hsp_query-from>
      <Hsp_query-to>1488</Hsp_query-to>
      <Hsp_hit-from>22</Hsp_hit-from>
      <Hsp_hit-to>209</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>189</Hsp_align-len>
      <Hsp_qseq>VYTCVNVDTGE---LMAMK----EPNDHKTIKETADEIKIFEGINHSNLVRYYGVELHRE--EMYIFMEYCDEGTLEEVSRLGLQEP----VIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQTMPGEVNS--------TLG----TAAADIWSLGCVLIEMATGK</Hsp_qseq>
      <Hsp_hseq>VYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDI-VHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRK</Hsp_hseq>
      <Hsp_midline>VY  +++  G+   ++A+K    E  D         EI + + +   N+VR Y + +H +  ++Y+  E+ D      +  +   +P    +++ +  Q+C  I   H   I+HRD+K  N+ +   G++KLGDFG +       +    E+ +         LG    +   D WS+GC+  EM   K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>2.29432e-12</Hsp_evalue>
      <Hsp_query-from>1021</Hsp_query-from>
      <Hsp_query-to>1515</Hsp_query-to>
      <Hsp_hit-from>35</Hsp_hit-from>
      <Hsp_hit-to>228</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>195</Hsp_align-len>
      <Hsp_qseq>TGELMAMK--EPNDHKTIK-ETADEIKIFEGINHSNLVRYYGVEL-----HREEMYIFMEYCDEGTLEEVSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCS--VKLKNISQTMP-GE-------------------VNSTLGTAAADIWSLGCVLIEMATGKRLSPEGRDF</Hsp_qseq>
      <Hsp_hseq>TGEIVAIKKIEPFDKPLFALRTLREIKILKHFKHENIITIFNIQRPDSFENFNEVYIIQELMQTDLHRVISTQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFP-GRDY</Hsp_hseq>
      <Hsp_midline>TGE++A+K  EP D       T  EIKI +   H N++  + ++      +  E+YI  E         +S   L +  I+++  Q   A+  LH   ++HRD+K +N+ + S   +K+ DFG +  +       + P G+                   + S   + A D+WS GC+L E+   + + P GRD+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>2.6251e-12</Hsp_evalue>
      <Hsp_query-from>1084</Hsp_query-from>
      <Hsp_query-to>1590</Hsp_query-to>
      <Hsp_hit-from>77</Hsp_hit-from>
      <Hsp_hit-to>286</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>51</Hsp_gaps>
      <Hsp_align-len>215</Hsp_align-len>
      <Hsp_qseq>EIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEE--VSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQTMPGEVNSTLGTA----------------AADIWSLGCVLIEMATGK----------------------------RLSPEGRDFLALCLESDPSDRCTASQLLDHAFVK</Hsp_qseq>
      <Hsp_hseq>EIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAA-----LQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLK</Hsp_hseq>
      <Hsp_midline>EI I + ++H N++  Y V      +Y+ +EY ++G L    V    L E    +  +QI   I+  H  GIVHRD+K  N+ L S  +IK+ DFG +       QT    + ++ G+                 A+D+WS G +L  + TG+                             +S + +D +   L  DP  R     +L H  +K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>2.99144e-12</Hsp_evalue>
      <Hsp_query-from>922</Hsp_query-from>
      <Hsp_query-to>1512</Hsp_query-to>
      <Hsp_hit-from>9</Hsp_hit-from>
      <Hsp_hit-to>221</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>221</Hsp_align-len>
      <Hsp_qseq>RRRVVGRVCSTPHAINNLMHVGLRK---VYTCVNVDTGELMAMKE---PNDHKTI-KETADEIKIFEGINHSNLVRYYGVELHR-EEMYIFMEYCDEGTLEEVSRL----GLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQTMPGEVNSTLGTAA------------ADIWSLGCVLIEMATGKRLSPEGRD</Hsp_qseq>
      <Hsp_hseq>RTQIFGTVFEITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLSPLEDIYFVTEL--QGT--DLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLA-RIQD--PQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFP-GKD</Hsp_hseq>
      <Hsp_midline>R ++ G V    +  N+L  VG+     V +  +  T + +A+K+   P     + K T  E+K+ + + H NL+    + L   E++Y   E   +GT  ++ RL     L++  ++++  QI   +  +H  G++HRD+K +NI +     +K+ DFG + ++++    M G V++    A              DIWS GC+  EM  GK L P G+D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>4.48977e-12</Hsp_evalue>
      <Hsp_query-from>1153</Hsp_query-from>
      <Hsp_query-to>1485</Hsp_query-to>
      <Hsp_hit-from>418</Hsp_hit-from>
      <Hsp_hit-to>541</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>126</Hsp_align-len>
      <Hsp_qseq>EEMYIFMEYCDEGTL----EEVSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFG-CSVKLKNISQT---------MPGEVNSTLG-TAAADIWSLGCVLIEMATG</Hsp_qseq>
      <Hsp_hseq>EKLYFVLAFINGGELFYHLQKEGRFDLSR--ARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTG</Hsp_hseq>
      <Hsp_midline>E++Y  + + + G L    ++  R  L     R YT ++  A+  LH+  +V+RD+K  NI L   GHI L DFG C + +K+  +T         +  E+   LG T A D W+LG +L EM TG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>4.81883e-12</Hsp_evalue>
      <Hsp_query-from>1033</Hsp_query-from>
      <Hsp_query-to>1494</Hsp_query-to>
      <Hsp_hit-from>65</Hsp_hit-from>
      <Hsp_hit-to>239</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>177</Hsp_align-len>
      <Hsp_qseq>MAMKEPNDHKTIKETADEIKIFEGINHSNLVR--YYGVELHREEMYIF----MEYCDEGTLEEVSRL---GLQEPV--IRHYTKQICTAITELHERGIVHRDIKGANIFLTS-TGHIKLGDFGCSVKLKNISQTMPG-----------EVNSTLGTAAADIWSLGCVLIEMATGKRL</Hsp_qseq>
      <Hsp_hseq>FAIKKVPAHTEYK--SRELQILRIADHPNIVKLQYFFTHLSPQDNKVYQHLAMECLPETLQIEINRYVTNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSISYICSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAI</Hsp_hseq>
      <Hsp_midline> A+K+   H   K  + E++I    +H N+V+  Y+   L  ++  ++    ME   E    E++R     L+ P+  IR YT QI   +  LH  G+ HRDIK +N+ +   TG +K+ DFG + KL++   ++              +  T  T   DIW LGCV+ EM  GK +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>5.19246e-12</Hsp_evalue>
      <Hsp_query-from>904</Hsp_query-from>
      <Hsp_query-to>1488</Hsp_query-to>
      <Hsp_hit-from>29</Hsp_hit-from>
      <Hsp_hit-to>227</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>56</Hsp_gaps>
      <Hsp_align-len>225</Hsp_align-len>
      <Hsp_qseq>LDAQSQRRRVVGRVCSTPHAINNLMHVGLRKVYTCVNVDTGELMAMKEPNDHKTIKETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEG-TLEEVSRLG-LQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGC-----------SVKLKNISQTMPGEVN--STLGTA---------------AADIWSLGCVLIEMATGK</Hsp_qseq>
      <Hsp_hseq>LDKKSPNKIYAIKVCSKKHIIKEA-----KVKYVTIEKNTMNLLAQKH---------------------HAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQ</Hsp_hseq>
      <Hsp_midline>LD +S  +    +VCS  H I        +  Y  +  +T  L+A K                      H+ +++ Y      E +Y  +++   G  L  + ++G   +   RH+T Q+  A+  +H  GI+HRD+K  N+ L   G + + DFG            S K  + S       N  S +GTA                +DIW+LGC++ +   G+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>6.33518e-12</Hsp_evalue>
      <Hsp_query-from>997</Hsp_query-from>
      <Hsp_query-to>1494</Hsp_query-to>
      <Hsp_hit-from>16</Hsp_hit-from>
      <Hsp_hit-to>221</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>208</Hsp_align-len>
      <Hsp_qseq>VYTCVNVDTGELMAMKEPNDHKT----IKETADEIKIFEGIN-HSNLVRYYGVELHREEMYIFM--EYCDEGTLEEV----------SRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNIS------------QTMPGEVNST-------------LGTAAADIWSLGCVLIEMATGKRL</Hsp_qseq>
      <Hsp_hseq>VYKAWSTTHNRYVALKITPKYKTSEANMKNEYDVMKILSSCNPHPNICS--MLDFYTDDSYYIMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQIDMQKIIKQLCSAISFAHSLGIAHRDIKPENILLTINGDIKLADWGHAIQSPKSNDFQIGTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFGDCL</Hsp_hseq>
      <Hsp_midline>VY   +      +A+K    +KT    +K   D +KI    N H N+     ++ + ++ Y  M  EYC+ G L +           S   L +  ++   KQ+C+AI+  H  GI HRDIK  NI LT  G IKL D+G +++    +            +T  G V+++               T  AD WSLG  +  +  G  L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>1.41246e-11</Hsp_evalue>
      <Hsp_query-from>1066</Hsp_query-from>
      <Hsp_query-to>1485</Hsp_query-to>
      <Hsp_hit-from>538</Hsp_hit-from>
      <Hsp_hit-to>713</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>176</Hsp_align-len>
      <Hsp_qseq>IKETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEG----TLEEVSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNIS-QTMPGEVNSTL-------------------------------GTAAADIWSLGCVLIEMATG</Hsp_qseq>
      <Hsp_hseq>IKRVLTEQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFG</Hsp_hseq>
      <Hsp_midline>IK    E +I    NH  +V  Y      + +Y+ MEYC  G     L+      + E   R Y  ++  A+  LH  G ++RD+K  NI L  +GHI L DF  S++ K+     + G   STL                                TAA D W+LG ++ EM  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>5.17166e-11</Hsp_evalue>
      <Hsp_query-from>1069</Hsp_query-from>
      <Hsp_query-to>1488</Hsp_query-to>
      <Hsp_hit-from>168</Hsp_hit-from>
      <Hsp_hit-to>320</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>153</Hsp_align-len>
      <Hsp_qseq>KETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEE--VSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQ----------TMPGEVNSTLGTAA-ADIWSLGCVLIEMATGK</Hsp_qseq>
      <Hsp_hseq>KRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGK</Hsp_hseq>
      <Hsp_midline>K T  E  + + + H ++ R + +       Y+  EY   G L +  +    L+E   R + + I +A+  LH   IVHRD+K  NI ++S+G IK+ DFG S       Q            P  + +   T    DIWS G VL  +  GK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>6.77402e-11</Hsp_evalue>
      <Hsp_query-from>1084</Hsp_query-from>
      <Hsp_query-to>1488</Hsp_query-to>
      <Hsp_hit-from>104</Hsp_hit-from>
      <Hsp_hit-to>273</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>173</Hsp_align-len>
      <Hsp_qseq>EIKIFEGINHSNLVRYYGV--ELHREEMYIFMEYCDEGTLE-------EVSRLGLQEPVI------RHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLK----NISQTMPGEVNS-TLGT------------------AAADIWSLGCVLIEMATGK</Hsp_qseq>
      <Hsp_hseq>EIEVMKRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAVG---PSILTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGK</Hsp_hseq>
      <Hsp_midline>EI++ +  +H N+V  Y +  +    ++Y+ +EYC  G ++       E+  +G   P I      R     + + +  LH +GI HRDIK +N+ ++S G +K+ DFG ++       NI  +    + S  LGT                  +A DIWSLG  +  +  GK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>8.63816e-11</Hsp_evalue>
      <Hsp_query-from>1153</Hsp_query-from>
      <Hsp_query-to>1590</Hsp_query-to>
      <Hsp_hit-from>415</Hsp_hit-from>
      <Hsp_hit-to>600</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>188</Hsp_align-len>
      <Hsp_qseq>EEMYIFMEYCDEGTL----EEVSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFG-CSVKLKNISQT---------MPGEVNSTLG-TAAADIWSLGCVLIEMATG------------------------KRLSPEGRDFLALCLESDPSDRCTAS---QLLDHAFVK</Hsp_qseq>
      <Hsp_hseq>EKLYLVLAFINGGELFYHLQHEGRFSLARS--RFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAAKDLLIGLLSRDPSRRLGVNGTDEIRNHPFFK</Hsp_hseq>
      <Hsp_midline>E++Y+ + + + G L    +   R  L     R Y  ++  A+  LH+  +++RD+K  NI L   GHI L DFG C + +K+  +T         +  E+    G T   D W+LG +L EM TG                            P  +D L   L  DPS R   +   ++ +H F K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>1.14359e-10</Hsp_evalue>
      <Hsp_query-from>916</Hsp_query-from>
      <Hsp_query-to>1506</Hsp_query-to>
      <Hsp_hit-from>421</Hsp_hit-from>
      <Hsp_hit-to>656</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>240</Hsp_align-len>
      <Hsp_qseq>SQRRRVV--GRVCSTPHA-----INNLMHVG---LRKVYTCVNVDTGELMAMK--EPNDHKTIKETADEIKIFEGINHS---------NLVRYYGVELHREEMYIFMEYCDEGTLEEVSRLGLQEPVIRHYTK-----------QICTAITELHER-GIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQTMPGE----------VNSTLGTAAADIWSLGCVLIEMATGKRLSPEG</Hsp_qseq>
      <Hsp_hseq>NSKRRLISSNKLSANPDSHLFEKFTNVHSIGKGQFSTVYQVTFAQTNKKYAIKAIKPNKYNSLKRILLEIKILNEVTNQITMDQEGKEYIIDYISSWKFQNSYYIMTELCENGNLDGF----LQEQVIAKKKRLEDWRIWKIIVELSLALRFIHDSCHIVHLDLKPANVMITFEGNLKLGDFGMATHLPLEDKSFENEGDREYIAPEIISDCTYDYKADIFSLGLMIVEIAANVVLPDNG</Hsp_hseq>
      <Hsp_midline>+ +RR++   ++ + P +       N+  +G      VY      T +  A+K  +PN + ++K    EIKI   + +           ++ Y      +   YI  E C+ G L+      LQE VI    +           ++  A+  +H+   IVH D+K AN+ +T  G++KLGDFG +  L    ++   E          ++       ADI+SLG +++E+A    L   G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>1.17943e-10</Hsp_evalue>
      <Hsp_query-from>1084</Hsp_query-from>
      <Hsp_query-to>1467</Hsp_query-to>
      <Hsp_hit-from>894</Hsp_hit-from>
      <Hsp_hit-to>1039</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>148</Hsp_align-len>
      <Hsp_qseq>EIKIFEGINHS---NLVRYYGVELHREEMYIFME---YCDEGTLEEVSRLGLQEPVIRHYTK----QICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKN-----ISQTMPGEVNSTLGTAA-----ADIWSLGCVL</Hsp_qseq>
      <Hsp_hseq>EIQIMATLNKNSQENILKL--LDFFEDDDYYYIETPVHGETGSIDLFDVIEFKKDMVEHEAKLVFKQVVASIKHLHDQGIVHRDIKDENVIVDSHGFVKLIDFGSAAYIKSGPFDVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLL</Hsp_hseq>
      <Hsp_midline>EI+I   +N +   N+++   ++   ++ Y ++E   + + G+++    +  ++ ++ H  K    Q+  +I  LH++GIVHRDIK  N+ + S G +KL DFG +  +K+        TM       LG ++      DIW+LG +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>2.13545e-10</Hsp_evalue>
      <Hsp_query-from>1156</Hsp_query-from>
      <Hsp_query-to>1560</Hsp_query-to>
      <Hsp_hit-from>487</Hsp_hit-from>
      <Hsp_hit-to>658</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>EMYIFMEYCDEGTL-EEVSRLG-LQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCS-VKLKNISQTMPGE---------VNSTLGTAAADIWSLGCVLIEM-------------------ATGK------RLSPEGRDFLALCLESDPSDRCTA</Hsp_qseq>
      <Hsp_hseq>DLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNRNPKHRLGA</Hsp_hseq>
      <Hsp_midline>++Y+  +Y   G L   + + G   E   + Y  ++  A+  LH+  IV+RD+K  NI L + G+I L DFG S   LK+ + T  G          ++ T  T   D WSLG ++ EM                   A GK       LS EGR F+   L  +P  R  A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>2.38779e-10</Hsp_evalue>
      <Hsp_query-from>1054</Hsp_query-from>
      <Hsp_query-to>1587</Hsp_query-to>
      <Hsp_hit-from>188</Hsp_hit-from>
      <Hsp_hit-to>398</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>215</Hsp_align-len>
      <Hsp_qseq>DHKTIKETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEE--VSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQ----------TMPGEVNSTLGTAA-ADIWSLGCVLIEMATGK------------------------RLSPEGRDFLALCLESDPSDRCTASQLLDHAFV</Hsp_qseq>
      <Hsp_hseq>DKRTIREAS----LGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKIKQGKVEYPQHLSIEVISLLSKMLVVDPKRRATLKQVVEHHWM</Hsp_hseq>
      <Hsp_midline>D +TI+E +    + + + H ++ R + +       Y+  EY   G L +  +    ++E   R + + I +A+  LH   IVHRD+K  NI ++ +  IK+ DFG S    +  Q            P  + +   T    D+WS G VL  +  GK                         LS E    L+  L  DP  R T  Q+++H ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>3.70963e-10</Hsp_evalue>
      <Hsp_query-from>1138</Hsp_query-from>
      <Hsp_query-to>1476</Hsp_query-to>
      <Hsp_hit-from>225</Hsp_hit-from>
      <Hsp_hit-to>358</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>134</Hsp_align-len>
      <Hsp_qseq>VELHREEMYIFMEYCDEGTLEEV------SRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQTM--PGEVNSTLG-------------TAAADIWSLGCVLIEM</Hsp_qseq>
      <Hsp_hseq>IFLERKCVHMVYEYAEHDLLQIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDGCVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAEL</Hsp_hseq>
      <Hsp_midline>+ L R+ +++  EY +   L+ +       +  +   ++R    Q+   ++ LH+  ++HRD+K ANI +T  G +K+GD G + K  N+ QT+    +V  T+              T A D+WS+GC+  E+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>3.83313e-10</Hsp_evalue>
      <Hsp_query-from>1060</Hsp_query-from>
      <Hsp_query-to>1494</Hsp_query-to>
      <Hsp_hit-from>78</Hsp_hit-from>
      <Hsp_hit-to>248</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>171</Hsp_align-len>
      <Hsp_qseq>KTIKETADEIKIFEGINHSNLVRY-YGVELH---REEMYIF-----MEYCDEGTLEEVSRL---GLQEPV--IRHYTKQICTAITELHERGIVHRDIKGANIFLT-STGHIKLGDFGCSVKLKNISQTMPGE-----------VNSTLGTAAADIWSLGCVLIEMATGKRL</Hsp_qseq>
      <Hsp_hseq>KSPKVQSLELEILQNIRHPNLVTLEFFFESHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGIAKVCDFGSAQRLDDNTELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPL</Hsp_hseq>
      <Hsp_midline>K+ K  + E++I + I H NLV   +  E H   ++  +++     MEY  +    E+      G + P   I+ YT QI  A+  LH   I H D+K +NI +  S+G  K+ DFG + +L + ++                +NS   T   DIWSLGC++ EM  G+ L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>5.95818e-10</Hsp_evalue>
      <Hsp_query-from>994</Hsp_query-from>
      <Hsp_query-to>1599</Hsp_query-to>
      <Hsp_hit-from>68</Hsp_hit-from>
      <Hsp_hit-to>310</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>245</Hsp_align-len>
      <Hsp_qseq>KVYTCVNVDTGELMAMKEPNDHKTIKETAD-------EIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEE-VSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLK--NISQTMPGEVNST---------LGTAAADIWSLGCVLIEM------------------------ATGKRLSPEGRDFLALCLESDPSDRCTASQLLDHAFVKVCL</Hsp_qseq>
      <Hsp_hseq>KVKLAYHTTTGQKVALKIIN--KKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGAAGLIKRMLIVNPLNRISIHEIMQDDWFKVDL</Hsp_hseq>
      <Hsp_midline>KV    +  TG+ +A+K  N  K +   +D       EI     + H ++++ Y V   ++E+ + +EY      +  V R  + E   R + +QI +A+   H   IVHRD+K  N+ L    ++K+ DFG S  +   N  +T  G  N                 D+WS G +L  M                           K LSP     +   L  +P +R +  +++   + KV L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YPR111W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:747306:749000:1 gene:YPR111W transcript:YPR111W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF20 description:Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006315]</Hit_def>
  <Hit_accession>YPR111W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>6.7778e-10</Hsp_evalue>
      <Hsp_query-from>985</Hsp_query-from>
      <Hsp_query-to>1485</Hsp_query-to>
      <Hsp_hit-from>179</Hsp_hit-from>
      <Hsp_hit-to>403</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>60</Hsp_gaps>
      <Hsp_align-len>226</Hsp_align-len>
      <Hsp_qseq>GLRKVYTCVNVDTGELMAMKEPNDHKTIK-----ETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEG---TLEEVSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGC-----------SVKLK-------------------------NISQTMPGEVNSTLGTA---------------AADIWSLGCVLIEMATG</Hsp_qseq>
      <Hsp_hseq>GYGQVYLAKKKDSDEICALKILNKKLLFKLNETNHVLTERDILTTTRSDWLVKLLYAFQDPESLYLAMEFVPGGDFRTLLINTRI-LKSGHARFYISEMFCAVNALHELGYTHRDLKPENFLIDATGHIKLTDFGLAAGTVSNERIESMKIRLEEVKNLEFPAFTERSIEDRRKIYHNMRKTEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVG</Hsp_hseq>
      <Hsp_midline>G  +VY     D+ E+ A+K  N     K         E  I        LV+        E +Y+ ME+   G   TL   +R+ L+    R Y  ++  A+  LHE G  HRD+K  N  + +TGHIKL DFG            S+K++                         N+ +T     NS +G+                  D WSLGC+L E   G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>8.21126e-10</Hsp_evalue>
      <Hsp_query-from>1018</Hsp_query-from>
      <Hsp_query-to>1374</Hsp_query-to>
      <Hsp_hit-from>373</Hsp_hit-from>
      <Hsp_hit-to>498</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>126</Hsp_align-len>
      <Hsp_qseq>DTGELMAMK-----EPNDHKTIKETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEE-VSRLGL-QEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSV</Hsp_qseq>
      <Hsp_hseq>DTGKIYAMKTLLKSEMYKKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLST</Hsp_hseq>
      <Hsp_midline>DTG++ AMK     E      +     E  +  G +   +V  Y      + +Y+ ME+   G L   + R  L  E V R Y  +   AI  +H+ G +HRDIK  NI +   GHIKL DFG S </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>8.68715e-10</Hsp_evalue>
      <Hsp_query-from>1018</Hsp_query-from>
      <Hsp_query-to>1485</Hsp_query-to>
      <Hsp_hit-from>46</Hsp_hit-from>
      <Hsp_hit-to>263</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>62</Hsp_gaps>
      <Hsp_align-len>218</Hsp_align-len>
      <Hsp_qseq>DTGELMAMKEPN-----DHKTIKETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEEV--------------------------SRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTS--TGH-------------------IKLGDFGCSVKLKN--ISQTM--------PGEVNSTLGTAAADIWSLGCVLIEMATG</Hsp_qseq>
      <Hsp_hseq>DKSQHVAIKEVSRAKLKNKKLLENLEIEIAILKKIKHPHIVGLIDCERTSTDFYLIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVVFEMCCG</Hsp_hseq>
      <Hsp_midline>D  + +A+KE +     + K ++    EI I + I H ++V     E    + Y+ MEYC  G L  +                          +  GL    +  Y +Q+ +A+  L  + +VHRDIK  N+ L++   G+                   +K+ DFG +  L N  +++T+        P  +N     A AD+WS+G V+ EM  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.5362</Hsp_bit-score>
      <Hsp_score>140</Hsp_score>
      <Hsp_evalue>9.21694e-10</Hsp_evalue>
      <Hsp_query-from>997</Hsp_query-from>
      <Hsp_query-to>1500</Hsp_query-to>
      <Hsp_hit-from>53</Hsp_hit-from>
      <Hsp_hit-to>241</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>191</Hsp_align-len>
      <Hsp_qseq>VYTCVNVDTGELMAMKEPNDHKTIKETADEIKIFEGINHSNLV--RYYGVELH-REEMYI--FMEYCDEGTLEEV-----SRLGLQEPVIRHYTKQICTAITELHE-RGIVHRDIKGANIFLTS-TGHIKLGDFGCSVKLK----NISQT------MPGEV-NSTLGTAAADIWSLGCVLIEMATGKRLSP</Hsp_qseq>
      <Hsp_hseq>VFATVIQETNEKVAIKKVLQDKRFKNR--ELEIMKMLSHINIIDLKYFFYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFP</Hsp_hseq>
      <Hsp_midline>V+  V  +T E +A+K+    K  K    E++I + ++H N++  +Y+  E   ++E+Y+   +EY  +   + +      R  +    I++Y  Q+  ++  LH    + HRDIK  N+ +   T  +KL DFG + +LK    N+S         P  +  +T  T   DIWS GCV+ E+  G+ + P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.5362</Hsp_bit-score>
      <Hsp_score>140</Hsp_score>
      <Hsp_evalue>1.1054e-09</Hsp_evalue>
      <Hsp_query-from>1012</Hsp_query-from>
      <Hsp_query-to>1596</Hsp_query-to>
      <Hsp_hit-from>56</Hsp_hit-from>
      <Hsp_hit-to>301</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>57</Hsp_gaps>
      <Hsp_align-len>249</Hsp_align-len>
      <Hsp_qseq>NVDTGELMAMK------EPNDHKTIKETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTL-EEVSRLG--LQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFL---TSTGHIKLGDFGCSVKLKNISQTMPGEVNSTLGTAAA------------DIWSLGCV-------------------LIEMATGK-----------RLSPEGRDFLALCLESDPSDRCTASQLLDHAFVKVC</Hsp_qseq>
      <Hsp_hseq>NTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILV-EILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGS-LGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAELLEDPWI-IC</Hsp_hseq>
      <Hsp_midline>N +TGE +A+K         +   ++   DE+ I + ++H N+V +      +++ YI  +    G L + + + G   +E  +R    +I +A+  +H + IVHRD+K  N+     +    + + DFG + +LK+  + +     S LG  A             DIWS+G +                   L E  TG+            +S + + F+   L  DPS R TA++LL+  ++ +C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>1.36744e-09</Hsp_evalue>
      <Hsp_query-from>994</Hsp_query-from>
      <Hsp_query-to>1524</Hsp_query-to>
      <Hsp_hit-from>382</Hsp_hit-from>
      <Hsp_hit-to>579</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>198</Hsp_align-len>
      <Hsp_qseq>KVYTCVNVDTGELMAMKEPNDH-KTIKETADEIKIFEGINHS-------NLVRYYGVELHREEMYIFMEYCDEGTLEEVSR---LGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTG--HIKLGDFGCSVKLKNISQTM--------PGEVNSTLGTAAADIWSLGCVLIEMATGKRLSPEGRDFLAL</Hsp_qseq>
      <Hsp_hseq>QVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKNHLCLVFELLSNNLYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPELKIIDFGSSCEEARTVYTYIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAELFLGIPIFPGASEYNQL</Hsp_hseq>
      <Hsp_midline>+V  C N+ T E++A+K      + + ++  E KI E +N         + +R Y   +H+  + +  E       E + +    GL   +IR +T QI  ++  L E  ++H D+K  NI L +     +K+ DFG S +      T         P  +     + + D+WSLGC++ E+  G  + P   ++  L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>1.42203e-09</Hsp_evalue>
      <Hsp_query-from>1252</Hsp_query-from>
      <Hsp_query-to>1611</Hsp_query-to>
      <Hsp_hit-from>140</Hsp_hit-from>
      <Hsp_hit-to>299</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>QICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFG----CSVK--LKNISQT---MPGEV--NSTLGTAAADIWSLGCVLIEMATG-------------------------KRLSPEGRDFLALCLESDPSDRCTASQLLDHAFVK----VCLDQDE</Hsp_qseq>
      <Hsp_hseq>QISGAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTRECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDAKVIPDDARDLISRLLAKNPGERPSLSQVLRHPFLQPYGSVVLDQTQ</Hsp_hseq>
      <Hsp_midline>QI  A+   H    VHRD+K  NI L   G+ KL DFG    C  K  L+ +  T   M  E+    T      DIWSLG +L  + TG                         K +  + RD ++  L  +P +R + SQ+L H F++    V LDQ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YAR018C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:170396:171703:-1 gene:YAR018C transcript:YAR018C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN3 description:Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol [Source:SGD;Acc:S000000071]</Hit_def>
  <Hit_accession>YAR018C</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>1.53119e-09</Hsp_evalue>
      <Hsp_query-from>961</Hsp_query-from>
      <Hsp_query-to>1524</Hsp_query-to>
      <Hsp_hit-from>38</Hsp_hit-from>
      <Hsp_hit-to>296</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>91</Hsp_gaps>
      <Hsp_align-len>269</Hsp_align-len>
      <Hsp_qseq>AINNLMHVGLRKVYTCVNVDTGELMAMKEPNDHKTIKETADEIKIFEGINHSNLVRYYGVEL--HREEMYIFMEYCDEGTLEEVSRLGLQ------EPVIRHYTKQICTAITELH---------------------ERGIVHRDIKGANIFLTS-----------TGH----------------------------IKLGDFGCSVKLKNISQTMPGEVNSTLGTAA-----------ADIWSLGCVLIEMATGKRLSP--EGRDFLAL</Hsp_qseq>
      <Hsp_hseq>SVRKVIHIPTKKLLVRKDIKYGHM-------NSKERQQLIAECSILSQLKHENIVEFYNWDFDEQKEVLYLYMEYCSRGDLSQMIKHYKQEHKYIPEKIVWGILAQLLTALYKCHYGVELPTLTTIYDRMKPPVKGKNIVIHRDLKPGNIFLSYDDSDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLAKSLETSIQFATTYVGTPYYMSPEVLMDQPYSPLSDIWSLGCVIFEMCS---LHPPFQAKNYLEL</Hsp_hseq>
      <Hsp_midline>++  ++H+  +K+    ++  G +       + K  ++   E  I   + H N+V +Y  +    +E +Y++MEYC  G L ++ +   Q      E ++     Q+ TA+ + H                     +  ++HRD+K  NIFL+             GH                            +KLGDFG +  L+   Q     V +    +            +DIWSLGCV+ EM +   L P  + +++L L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>1.57415e-09</Hsp_evalue>
      <Hsp_query-from>1084</Hsp_query-from>
      <Hsp_query-to>1374</Hsp_query-to>
      <Hsp_hit-from>192</Hsp_hit-from>
      <Hsp_hit-to>300</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>111</Hsp_align-len>
      <Hsp_qseq>EIKIFEGINHSNLVRYYGV--ELHREEMYIFMEYCDEGTLE------------EVSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSV</Hsp_qseq>
      <Hsp_hseq>EIAIMKKCHHKHVVQLIEVLDDLKSRKIYLVLEYCSRGEVKWCPPDCMESDAKGPSLLSFQE--TREILRGVVLGLEYLHYQGIIHRDIKPANLLISGDGTVKISDFGVSL</Hsp_hseq>
      <Hsp_midline>EI I +  +H ++V+   V  +L   ++Y+ +EYC  G ++              S L  QE   R   + +   +  LH +GI+HRDIK AN+ ++  G +K+ DFG S+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>1.88147e-09</Hsp_evalue>
      <Hsp_query-from>1012</Hsp_query-from>
      <Hsp_query-to>1467</Hsp_query-to>
      <Hsp_hit-from>219</Hsp_hit-from>
      <Hsp_hit-to>411</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>193</Hsp_align-len>
      <Hsp_qseq>NVDTGELMAMK-----EPNDHKTIKETADEIKIFEGINHSNLVRYYG-----VELHREEMYIFMEYCDEGTLEE--VSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTG-------------------HIKLGDFGCS-----VKLKNI-----SQTMPGEVNSTLGTAAADIWSLGCVL</Hsp_qseq>
      <Hsp_hseq>NKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVIL</Hsp_hseq>
      <Hsp_midline>N  TG+ +A+K     + +D K  K+  +E  I   + H N+V         +   + + Y+ +E  D+G L E  V +  L++   +   KQ+ T +  LHE+ I+HRDIK  NI L  T                     +K+ DFG +     ++  N      S   P  +     T+  D+WS G +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>3.55472e-09</Hsp_evalue>
      <Hsp_query-from>991</Hsp_query-from>
      <Hsp_query-to>1587</Hsp_query-to>
      <Hsp_hit-from>65</Hsp_hit-from>
      <Hsp_hit-to>309</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>246</Hsp_align-len>
      <Hsp_qseq>RKVYTCVNVDTGELMAMKEPNDHKTIKETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEE--VSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGH---IKLGDFGCSVKLKNISQTMPGEVNSTLGTAAA------------DIWSLGCV------------------LIEMATGKR------------LSPEGRDFLALCLESDPSDRCTASQLLDHAFV</Hsp_qseq>
      <Hsp_hseq>RKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKG-EEDLIYKAAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSPFIAESVEGFMEECTASRYPVTFHMPYWDNISIDVKRFILKALRLNPADRPTATELLDDPWI</Hsp_hseq>
      <Hsp_midline>RK+ T  +V    L+      ++  ++   +E+ I + ++H N+V +      +++ YI  +    G L +  +SR    E        QI  A+  +H + +VHRD+K  N+          + + DFG + +LK   + +  +   +LG  A             DIWS+G +                   +E  T  R            +S + + F+   L  +P+DR TA++LLD  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>8.6007e-09</Hsp_evalue>
      <Hsp_query-from>934</Hsp_query-from>
      <Hsp_query-to>1476</Hsp_query-to>
      <Hsp_hit-from>20</Hsp_hit-from>
      <Hsp_hit-to>276</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>88</Hsp_gaps>
      <Hsp_align-len>263</Hsp_align-len>
      <Hsp_qseq>VGRVCSTP----HAINNLMHVGLRK-----------------------------VYTCVNVDTGELMAMKE---PNDHKTIKETAD-EIKIFEGINHSNLVRYYGV--------------ELHREEMYIFMEY--CDEGTLEEVSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFG-------CSVKLKNISQTMPGEVNS------------------TLG----TAAADIWSLGCVLIEM</Hsp_qseq>
      <Hsp_hseq>IGKVKSTPAIQRDAKTNLTYIKLRKRSSEKVYGCTVFQNHYREDEKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKS-FYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLK-----YPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEF</Hsp_hseq>
      <Hsp_midline>+G+V STP     A  NL ++ LRK                             VY  ++++T   +AMK+     +      TA  EI I + +NH N+++   +               LH+   Y+ + Y   D   +    R+ L+   I++   QI   +  +H    +HRDIK ANI +   G +KL DFG       C   LK      PG   S                   LG    T A DIW +GCV  E </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>9.2965e-09</Hsp_evalue>
      <Hsp_query-from>1060</Hsp_query-from>
      <Hsp_query-to>1494</Hsp_query-to>
      <Hsp_hit-from>365</Hsp_hit-from>
      <Hsp_hit-to>528</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>164</Hsp_align-len>
      <Hsp_qseq>KTIKETADEIKIFEGINHSNLVRYYGVELHREEMYI-FMEYCDEGTLEE--VSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCS--VKL---KNISQT----------MPGE-VNSTLGTAAADIWSLGCVLIEMATGKRL</Hsp_qseq>
      <Hsp_hseq>KYSKRLTSEFCISSSLHHTNIVTTLDLFQDAKGEYCEVMEYCAGGDLFTLVVAAGKLEYMEADCFFKQLIRGVVYMHEMGVCHRDLKPENLLLTHDGVLKITDFGNSECFKMAWEKNIHLSGGVCGSSPYIAPEEYIKEEFDPRPVDIWACGVIYMAMRTGRQL</Hsp_hseq>
      <Hsp_midline>K  K    E  I   ++H+N+V    +    +  Y   MEYC  G L    V+   L+      + KQ+   +  +HE G+ HRD+K  N+ LT  G +K+ DFG S   K+   KNI  +           P E +         DIW+ G + + M TG++L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>1.04328e-08</Hsp_evalue>
      <Hsp_query-from>1156</Hsp_query-from>
      <Hsp_query-to>1488</Hsp_query-to>
      <Hsp_hit-from>155</Hsp_hit-from>
      <Hsp_hit-to>286</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>132</Hsp_align-len>
      <Hsp_qseq>EMYIFMEYCDEGTLEEVSR---LGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGH-IKLGDFGCSVKLK-----NISQ---TMPGEVNSTLGT---------AAADIWSLGCVLIEMATGK</Hsp_qseq>
      <Hsp_hseq>DSYIIMEYCSGGDLYEAIKADAVPKKTKSITHIITQIMDAIEYVHNKGIYHRDIKPENILISGIDWTIKLTDWGLATTDKTSMDRNVGSERYMSPELFDSNLDIKERKEPYDCAKVDLWAMGIVFLNIVFHK</Hsp_hseq>
      <Hsp_midline>+ YI MEYC  G L E  +   +  +   I H   QI  AI  +H +GI HRDIK  NI ++     IKL D+G +   K     N+       P   +S L           A  D+W++G V + +   K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>1.21811e-08</Hsp_evalue>
      <Hsp_query-from>1084</Hsp_query-from>
      <Hsp_query-to>1467</Hsp_query-to>
      <Hsp_hit-from>1149</Hsp_hit-from>
      <Hsp_hit-to>1294</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>154</Hsp_align-len>
      <Hsp_qseq>EIKIFEGIN---HSNLVRYYGVELHREEMYIFME---YCDEGTLEEVS----RLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQTMPGEVNSTLGT----------------AAADIWSLGCVL</Hsp_qseq>
      <Hsp_hseq>EIQIMATLNKKPHENILRL--LDFFEDDDYYYIETPVHGETGCIDLFDLIEFKTNMTEFEAKLIFKQVVAGIKHLHDQGIVHRDIKDENVIVDSKGFVKIIDFGSAAYVKS------GPFDVFVGTIDYAAPEVLGGNPYEGQPQDIWAIGILL</Hsp_hseq>
      <Hsp_midline>EI+I   +N   H N++R   ++   ++ Y ++E   + + G ++       +  + E   +   KQ+   I  LH++GIVHRDIK  N+ + S G +K+ DFG +  +K+      G  +  +GT                   DIW++G +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>2.00649e-08</Hsp_evalue>
      <Hsp_query-from>1111</Hsp_query-from>
      <Hsp_query-to>1476</Hsp_query-to>
      <Hsp_hit-from>884</Hsp_hit-from>
      <Hsp_hit-to>1017</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>HSNLVRYYGVELHREEMYIFMEYCDEGTLE---EVSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFG-CSVKLKNISQT----------MPGEVNSTLGTAAADIWSLGCVLIEM</Hsp_qseq>
      <Hsp_hseq>HPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQRLSVRR--AKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQM</Hsp_hseq>
      <Hsp_midline>H  L   Y        +Y  ME+   G L    +  RL ++    + Y  ++  A+   H+ G+++RD+K  NI LT  GHIK+ D+G C  ++   ++T           P  +     T A D W+ G +L +M</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YFL033C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:69115:74427:-1 gene:YFL033C transcript:YFL033C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM15 description:Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase [Source:SGD;Acc:S000001861]</Hit_def>
  <Hit_accession>YFL033C</Hit_accession>
  <Hit_len>1770</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>2.37459e-08</Hsp_evalue>
      <Hsp_query-from>1120</Hsp_query-from>
      <Hsp_query-to>1371</Hsp_query-to>
      <Hsp_hit-from>855</Hsp_hit-from>
      <Hsp_hit-to>940</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>86</Hsp_align-len>
      <Hsp_qseq>LVRYYGVELHREEMYIFMEYCDEGTLEEVSRLG--LQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCS</Hsp_qseq>
      <Hsp_hseq>VARLFASFQNKDNLFLVMEYLPGGDLATLIKMMGYLPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLIDNAGHVKLTDFGLS</Hsp_hseq>
      <Hsp_midline>+ R +    +++ +++ MEY   G L  + ++   L +   + Y  +I   + ++H+ GI+H D+K  N+ + + GH+KL DFG S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YPL026C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:500675:502183:-1 gene:YPL026C transcript:YPL026C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKS1 description:Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway; SKS1 has a paralog, VHS1, that arose from the whole genome duplication [Source:SGD;Acc:S000005947]</Hit_def>
  <Hit_accession>YPL026C</Hit_accession>
  <Hit_len>502</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>3.93933e-08</Hsp_evalue>
      <Hsp_query-from>1009</Hsp_query-from>
      <Hsp_query-to>1479</Hsp_query-to>
      <Hsp_hit-from>88</Hsp_hit-from>
      <Hsp_hit-to>269</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>185</Hsp_align-len>
      <Hsp_qseq>VNVDTGELMAMKEPNDHKTIKETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEEV---SRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQTM-------------------------PGEVNSTLGTAAADIWSLGCVLIEMA</Hsp_qseq>
      <Hsp_hseq>VDLDSILQLTENELNRLPHYREIAFQLRV---QSHGNIVKIHQVLESSIATFIVMDYYDRDLFTSIVDDKHFVNHGILIKKVFLQLCSALDHCHRLGIYHCDIKPENVLLDRNDNAYLCDFGLSTKSKYLAPNVCVGSSYYMAPERILYCLNTTTNGIHVDECCSSLPTDTGDIWSLGIILINLT</Hsp_hseq>
      <Hsp_midline>V++D+   +   E N     +E A ++++    +H N+V+ + V       +I M+Y D      +           +I+    Q+C+A+   H  GI H DIK  N+ L    +  L DFG S K K ++  +                           E  S+L T   DIWSLG +LI + </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>5.0108e-08</Hsp_evalue>
      <Hsp_query-from>1063</Hsp_query-from>
      <Hsp_query-to>1485</Hsp_query-to>
      <Hsp_hit-from>86</Hsp_hit-from>
      <Hsp_hit-to>248</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>163</Hsp_align-len>
      <Hsp_qseq>TIKETAD-EIKIFEGIN------HSNLVRYYGVELHREEMYIFMEYCDEGTLEEV--SRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQTM-----------PGEVNSTLGTAA--ADIWSLGCVLIEMATG</Hsp_qseq>
      <Hsp_hseq>TIKKDADKEIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAG</Hsp_hseq>
      <Hsp_midline>TIK+ AD EIKI+  IN      H N++    V  + + + I +E+   G   +    +  L+E        Q+ + +  +H +G+VHRD+K  N+ L    ++ + DFG   +    ++ M           P  V ST    A  AD+WS G +L  M  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>5.24921e-08</Hsp_evalue>
      <Hsp_query-from>985</Hsp_query-from>
      <Hsp_query-to>1485</Hsp_query-to>
      <Hsp_hit-from>187</Hsp_hit-from>
      <Hsp_hit-to>411</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>58</Hsp_gaps>
      <Hsp_align-len>225</Hsp_align-len>
      <Hsp_qseq>GLRKVYTCVNVDTGELMAMKEPNDH-----KTIKETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEE--VSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSV----------------KLKNI-----------------SQTMPGEV---NSTLGTA---------------AADIWSLGCVLIEMATG</Hsp_qseq>
      <Hsp_hseq>GYGQVYLARKKDTKEVCALKILNKKLLFKLNETKHVLTERDILTTTRSEWLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINTRCLKSGHARFYISEMFCAVNALHDLGYTHRDLKPENFLIDAKGHIKLTDFGLAAGTISNERIESMKIRLEKIKDLEFPAFTEKSIEDRRKMYNQLREKEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVG</Hsp_hseq>
      <Hsp_midline>G  +VY     DT E+ A+K  N          K    E  I        LV+        + +Y+ ME+   G      ++   L+    R Y  ++  A+  LH+ G  HRD+K  N  + + GHIKL DFG +                 K+K++                 +Q    E+   NS +G+                  D WSLGC+L E   G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>71</Hit_num>
  <Hit_id>YDL028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:400997:403291:-1 gene:YDL028C transcript:YDL028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MPS1 description:Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]</Hit_def>
  <Hit_accession>YDL028C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>6.44188e-08</Hsp_evalue>
      <Hsp_query-from>1054</Hsp_query-from>
      <Hsp_query-to>1488</Hsp_query-to>
      <Hsp_hit-from>476</Hsp_hit-from>
      <Hsp_hit-to>651</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>178</Hsp_align-len>
      <Hsp_qseq>DHKTIKETADEIKIFEGI-NHSNLVRYYGVELHREEMYIFMEYCDEGTLEEV----SRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLK----NI-SQTMPGEVNSTLGTA-----------------------AADIWSLGCVLIEMATGK</Hsp_qseq>
      <Hsp_hseq>DDSSIDGFKGEIELLEKLKDQKRVIQLLDYEMGDGLLYLIME-CGDHDLSQILNQRSGMPLDFNFVRFYTKEMLLCIKVVHDAGIVHSDLKPAN-FVLVKGILKIIDFGIANAVPEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYGK</Hsp_hseq>
      <Hsp_midline>D  +I     EI++ E + +   +++    E+    +Y+ ME C +  L ++    S + L    +R YTK++   I  +H+ GIVH D+K AN F+   G +K+ DFG +  +     NI  +T  G  N     A                        +D+WS GC++ +M  GK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>72</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>6.50978e-08</Hsp_evalue>
      <Hsp_query-from>1087</Hsp_query-from>
      <Hsp_query-to>1512</Hsp_query-to>
      <Hsp_hit-from>91</Hsp_hit-from>
      <Hsp_hit-to>254</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>167</Hsp_align-len>
      <Hsp_qseq>IKIFEGINHSNLVRYYGVEL----HREEMYIFMEYCDEGTLEEV-SRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCS----VKLKNISQTMPGEVNSTLGT----------------AAADIWSLGCVLIEMATGKRLSPEGRD</Hsp_qseq>
      <Hsp_hseq>MNFFKG--HKNIVNLIDLEIVTSSPYDGLYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVF-MGRD</Hsp_hseq>
      <Hsp_midline>+  F+G  H N+V    +E+      + +Y + E  D    + + S + L E  I+++  QI   +  +H   ++HRD+K  NI  T  G +K+ DFG +            T+   + + + T                 + DIW++GC+L E    K +   GRD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>73</Hit_num>
  <Hit_id>YDL214C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:74446:76545:-1 gene:YDL214C transcript:YDL214C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR2 description:Serine/threonine protein kinase; inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance; PRR2 has a paralog, NPR1, that arose from the whole genome duplication [Source:SGD;Acc:S000002373]</Hit_def>
  <Hit_accession>YDL214C</Hit_accession>
  <Hit_len>699</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>7.53217e-08</Hsp_evalue>
      <Hsp_query-from>1042</Hsp_query-from>
      <Hsp_query-to>1527</Hsp_query-to>
      <Hsp_hit-from>397</Hsp_hit-from>
      <Hsp_hit-to>578</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>183</Hsp_align-len>
      <Hsp_qseq>KEPNDHKTIKETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEEVSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQTMPGEVNSTLGTA----------------AADIWSLGCVLIEMATGKRLS---PEGRD--FLALC</Hsp_qseq>
      <Hsp_hseq>KRESERKYIKNIISEYCIASTLKNPNICETLEILYEKGKIFQILEYCEYDLFSLVMSEKMHYEEICCLFKQLINGVKYLHDIGLSHRDLKLDNCVVTRRGILKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFYFNEYDPRALDVWSVGIIFFCMIT-RRFPWKYPKVKDVQFKAFC</Hsp_hseq>
      <Hsp_midline>K  ++ K IK    E  I   + + N+     +   + +++  +EYC+      V    +    I    KQ+   +  LH+ G+ HRD+K  N  +T  G +KL DFG S        +   E N  +G+                 A D+WS+G +   M T +R     P+ +D  F A C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>74</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>1.17362e-07</Hsp_evalue>
      <Hsp_query-from>1051</Hsp_query-from>
      <Hsp_query-to>1590</Hsp_query-to>
      <Hsp_hit-from>89</Hsp_hit-from>
      <Hsp_hit-to>314</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>226</Hsp_align-len>
      <Hsp_qseq>NDHKTIKETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEEV--SRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFG-----CS-VKLKNISQTMPGEVNSTLGTAA-------ADIWSLGCVLIEMATG------KRLSPEG-------------------------RDFLALCLESDPSDRCTASQLLDHAFVK</Hsp_qseq>
      <Hsp_hseq>NDYRKEVKIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVNEFCSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGRLYNYINSTPLKFPDYILPIPRDLLRRMLVSDPKKRINLKQIKKHEWLK</Hsp_hseq>
      <Hsp_midline>ND++   +   EI   + ++H N+V+   V  +   + I +EY   G   +    +  L+E        Q+ + +  +H +G+VHRD+K  N+ L    ++ + DFG     CS  +L   S   P      L  +A       ADIWS G +L  +  G         +PEG                         RD L   L SDP  R    Q+  H ++K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>75</Hit_num>
  <Hit_id>YDL025C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:405344:407206:-1 gene:YDL025C transcript:YDL025C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RTK1 description:Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002183]</Hit_def>
  <Hit_accession>YDL025C</Hit_accession>
  <Hit_len>620</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>1.32143e-07</Hsp_evalue>
      <Hsp_query-from>1069</Hsp_query-from>
      <Hsp_query-to>1479</Hsp_query-to>
      <Hsp_hit-from>352</Hsp_hit-from>
      <Hsp_hit-to>504</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>153</Hsp_align-len>
      <Hsp_qseq>KETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEEVSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQTMPGEVNSTLGTA----------------AADIWSLGCVLIEMA</Hsp_qseq>
      <Hsp_hseq>KKVTTEFCIGSTLHHENIVETLDMLTEGDTYLLVMEYAPYDFFNLVMSNLMTQDEVNCYFKQLCHGVNYLHSMGLAHRDLKLDNCVVTKDGILKLIDFGSAVVFQYPYEDTIVKSHGIVGSDPYLAPELLKQTSYDPRVADVWSIAIIFYCMV</Hsp_hseq>
      <Hsp_midline>K+   E  I   ++H N+V    +    +   + MEY        V    + +  +  Y KQ+C  +  LH  G+ HRD+K  N  +T  G +KL DFG +V  +   +    + +  +G+                  AD+WS+  +   M </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>76</Hit_num>
  <Hit_id>YOR267C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:822588:824867:-1 gene:YOR267C transcript:YOR267C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRK1 description:Protein kinase; implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005793]</Hit_def>
  <Hit_accession>YOR267C</Hit_accession>
  <Hit_len>759</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>1.73156e-07</Hsp_evalue>
      <Hsp_query-from>1024</Hsp_query-from>
      <Hsp_query-to>1539</Hsp_query-to>
      <Hsp_hit-from>238</Hsp_hit-from>
      <Hsp_hit-to>439</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>204</Hsp_align-len>
      <Hsp_qseq>GELMAMKE-----PNDHKTIKETAD----EIKIFEGINHSNLVRYYGV--ELHREEMYIFMEYCDEGTLEEVSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQ---TM------------PGEVNST--LGTAAADIWSLG----CVLIEMATGKRLSPEGRDFLALCLESD</Hsp_qseq>
      <Hsp_hseq>GATFAVKEFRPRKPNE--SVKEYAKKCTAEFCIGSTLHHPNVIETVDVFSDSKQNKYYEVMEYCPIDFFAVVMTGKMSRGEINCCLKQLTEGVKYLHSMGLAHRDLKLDNCVMTSQGILKLIDFGSAVVFRYPFEDGVTMAHGIVGSDPYLAPEVITSTKSYDPQCVDIWSIGIIYCCMVLKRFPWKAPRDSDDNFRLYCMPDD</Hsp_hseq>
      <Hsp_midline>G   A+KE     PN+  ++KE A     E  I   ++H N++    V  +  + + Y  MEYC       V    +    I    KQ+   +  LH  G+ HRD+K  N  +TS G +KL DFG +V  +   +   TM            P  + ST        DIWS+G    C++++    K       +F   C+  D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>77</Hit_num>
  <Hit_id>YNL183C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:293137:295509:-1 gene:YNL183C transcript:YNL183C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NPR1 description:Protein kinase; stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p; negatively regulates Ldb19p-mediated endocytosis through phosphorylation of Ldb19p, which prevents its association with the plasma membrane; Npr1p activity is negatively regulated via phosphorylation by the TOR complex; NPR1 has a paralog, PRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005127]</Hit_def>
  <Hit_accession>YNL183C</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>1.83208e-07</Hsp_evalue>
      <Hsp_query-from>1066</Hsp_query-from>
      <Hsp_query-to>1374</Hsp_query-to>
      <Hsp_hit-from>482</Hsp_hit-from>
      <Hsp_hit-to>584</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>103</Hsp_align-len>
      <Hsp_qseq>IKETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEEVSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSV</Hsp_qseq>
      <Hsp_hseq>VKKITSEYCIGTTLNHPNIIETIEIVYENDRILQVMEYCEYDLFAIVMSNKMSYEEICCCFKQILTGVQYLHSIGLAHRDLKLDNCVINEKGIVKLIDFGAAV</Hsp_hseq>
      <Hsp_midline>+K+   E  I   +NH N++    +    + +   MEYC+      V    +    I    KQI T +  LH  G+ HRD+K  N  +   G +KL DFG +V</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>78</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>2.84478e-07</Hsp_evalue>
      <Hsp_query-from>943</Hsp_query-from>
      <Hsp_query-to>1518</Hsp_query-to>
      <Hsp_hit-from>37</Hsp_hit-from>
      <Hsp_hit-to>239</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>209</Hsp_align-len>
      <Hsp_qseq>VCSTPHAINNL-MHVGLRKVYTCVNVDTGELMAMKEPNDHKTIKETADEIKIFEGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEEVSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQTMPGEVNSTLG----------------TAAADIWSLGCVLIEMATGKRLSPEGRDFL</Hsp_qseq>
      <Hsp_hseq>ICSSTYTESNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFD----TDIVFYPNGALNGVYLYEELMECDLSQIIR-SEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAEL-LGRKPMFEGKDYV</Hsp_hseq>
      <Hsp_midline>+CS+ +  +N   HV +RK+             ++E    + ++   + + +F+    +++V Y    L+   +Y  +  CD   +   S   L++   + +  QI  A+  +H   ++H D+K  N+ + S   +K+ +FG S       +   G +   +                 T A DIWS GC+L E+  G++   EG+D++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>79</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>3.44358e-07</Hsp_evalue>
      <Hsp_query-from>997</Hsp_query-from>
      <Hsp_query-to>1476</Hsp_query-to>
      <Hsp_hit-from>21</Hsp_hit-from>
      <Hsp_hit-to>198</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>180</Hsp_align-len>
      <Hsp_qseq>VYTCVNVDTGELMAMKEPNDHKTIKETAD-----EIKIFEGINHSNLVRYYGVELHREEMYIFMEYCD---EGTLEEVSRLGLQEPVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNISQTMPGEV------------NSTLGTAAADIWSLGCVLIEM</Hsp_qseq>
      <Hsp_hseq>VYLGCQHSTGRKIAIKEIKTSE-FKDGLDMSAIREVKYLQEMQHPNVIELIDIFMAYDNLNLVLEFLPTDLEVVIKDKSIL-FTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAEL</Hsp_hseq>
      <Hsp_midline>VY      TG  +A+KE    +  K+  D     E+K  + + H N++    + +  + + + +E+     E  +++ S L      I+ +       +   H   I+HRD+K  N+  +  G IK+ DFG +  +    + +   V             +   T+A DIWS+G +  E+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>80</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>3.8223e-07</Hsp_evalue>
      <Hsp_query-from>1219</Hsp_query-from>
      <Hsp_query-to>1485</Hsp_query-to>
      <Hsp_hit-from>231</Hsp_hit-from>
      <Hsp_hit-to>352</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>122</Hsp_align-len>
      <Hsp_qseq>LQEPVIRHYTKQICTAITELHERGIVHRDIKGANI------FLTSTGHI------------------KLGDFGCSVKLKNISQTMP--------GEV-NSTLGTAAADIWSLGCVLIEMATG</Hsp_qseq>
      <Hsp_hseq>FSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLRNNTAKTPCGTIEYVASEVFTSKRYSMKVDMWSIGCVLFTLLCG</Hsp_hseq>
      <Hsp_midline>  E + RH   Q+  AI  +H  GIVHRD+K  N+      F    G +                  KL DFG + KL+N +   P         EV  S   +   D+WS+GCVL  +  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>81</Hit_num>
  <Hit_id>YHR079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:258244:261591:-1 gene:YHR079C transcript:YHR079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IRE1 description:Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; role in homeostatic adaptation to ER stress; Kar2p binds inactive Ire1p and releases from it upon ER stress [Source:SGD;Acc:S000001121]</Hit_def>
  <Hit_accession>YHR079C</Hit_accession>
  <Hit_len>1115</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>6.06451e-07</Hsp_evalue>
      <Hsp_query-from>1084</Hsp_query-from>
      <Hsp_query-to>1437</Hsp_query-to>
      <Hsp_hit-from>715</Hsp_hit-from>
      <Hsp_hit-to>854</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>EIKIF-EGINHSNLVRYYGVELHREEMYIFMEYCDEGTLEEVS-------RLGLQE---PVIRHYTKQICTAITELHERGIVHRDIKGANIFLTSTG-------------HIKLGDFGCSVKLKNISQTMPGEVNSTLGTAA</Hsp_qseq>
      <Hsp_hseq>EIKLLTESDDHPNVIRYYCSETTDRFLYIALELCNLNLQDLVESKNVSDENLKLQKEYNPI--SLLRQIASGVAHLHSLKIIHRDLKPQNILVSTSSRFTADQQTGAENLRILISDFGLCKKLDSGQSSFRTNLNNPSGTSG</Hsp_hseq>
      <Hsp_midline>EIK+  E  +H N++RYY  E     +YI +E C+    + V         L LQ+   P+     +QI + +  LH   I+HRD+K  NI ++++               I + DFG   KL +   +    +N+  GT+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>82</Hit_num>
  <Hit_id>YDL079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:312951:314748:-1 gene:YDL079C transcript:YDL079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRK1 description:Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication [Source:SGD;Acc:S000002237]</Hit_def>
  <Hit_accession>YDL079C</Hit_accession>
  <Hit_len>501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>7.23952e-07</Hsp_evalue>
      <Hsp_query-from>997</Hsp_query-from>
      <Hsp_query-to>1494</Hsp_query-to>
      <Hsp_hit-from>178</Hsp_hit-from>
      <Hsp_hit-to>364</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>192</Hsp_align-len>
      <Hsp_qseq>VYTCVNVDTGELMAMKEPNDHKTIKETADEIKIFEGINHSNLV--RYYGVELHREE---MYIFMEYCDEGT---LEEVSRLGLQEP--VIRHYTKQICTAITELHERG-IVHRDIKGANIFL-TSTGHIKLGDFGCSVKLK----NIS----------QTMPGEVNSTLGTAAADIWSLGCVLIEMATGKRL</Hsp_qseq>
      <Hsp_hseq>VVTTVIIETNQKVAIKKVLQDRRYKNR--ELETMKMLCHPNTVGLQYYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYICSRYYRAPELMFGATNYS---NQVDVWSSACVIAELLLGKPL</Hsp_hseq>
      <Hsp_midline>V T V ++T + +A+K+    +  K    E++  + + H N V  +YY  E   E+   + + ++Y  +     L     L +Q P   I+ Y  Q+  A+  LH    I HRDIK  N+ +  +T   K+ DFG +  LK    N+S          + M G  N +      D+WS  CV+ E+  GK L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>83</Hit_num>
  <Hit_id>YDR247W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:956013:957398:1 gene:YDR247W transcript:YDR247W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VHS1 description:Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; VHS1 has a paralog, SKS1, that arose from the whole genome duplication [Source:SGD;Acc:S000002655]</Hit_def>
  <Hit_accession>YDR247W</Hit_accession>
  <Hit_len>461</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>1.11954e-06</Hsp_evalue>
      <Hsp_query-from>1252</Hsp_query-from>
      <Hsp_query-to>1479</Hsp_query-to>
      <Hsp_hit-from>168</Hsp_hit-from>
      <Hsp_hit-to>268</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>101</Hsp_align-len>
      <Hsp_qseq>QICTAITELHERGIVHRDIKGANIFLTSTGHIKLGDFGCSVKLKNI--------SQTMP-------GEVNST------LG----TAAADIWSLGCVLIEMA</Hsp_qseq>
      <Hsp_hseq>QICSALNYCHEHGIYHCDIKPENLLLDTEDNVFLCDFGLSTTSTYIKPNVCIGSSYYMPPERISFDGRVSSSKSGGHKLGKVCPSCNGDLWSLGIILINLT</Hsp_hseq>
      <Hsp_midline>QIC+A+   HE GI H DIK  N+ L +  ++ L DFG S     I        S  MP       G V+S+      LG    +   D+WSLG +LI + </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>84</Hit_num>
  <Hit_id>YNL020C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:595623:597539:-1 gene:YNL020C transcript:YNL020C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ARK1 description:Serine/threonine protein kinase; involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis; ARK1 has a paralog, PRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004965]</Hit_def>
  <Hit_accession>YNL020C</Hit_accession>
  <Hit_len>638</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>2.05052e-06</Hsp_evalue>
      <Hsp_query-from>1156</Hsp_query-from>
      <Hsp_query-to>1476</Hsp_query-to>
      <Hsp_hit-from>104</Hsp_hit-from>
      <Hsp_hit-to>239</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>EMYIFMEYCDEGTLEEVSRLGLQ----EPVIRHYTKQICTAITELH--ERGIVHRDIKGANIFLTSTGHIKLGDFGC----------SVKLKNISQTM----------PGEVNSTLGTA---AADIWSLGCVLIEM</Hsp_qseq>
      <Hsp_hseq>EVFVLMEYCERGGLIDFMNTRLQNRLHEFEILQIMSQVTQGVAAMHALQPPLIHRDIKIENVLISANNEYKLCDFGSVCGIIRPPRNSQELSYVQQDILKNTTAQYRSPEMIDTFRGLPIDEKSDIWALGIFLYKL</Hsp_hseq>
      <Hsp_midline>E+++ MEYC+ G L +     LQ    E  I     Q+   +  +H  +  ++HRDIK  N+ +++    KL DFG           S +L  + Q +          P  +++  G      +DIW+LG  L ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>85</Hit_num>
  <Hit_id>YIL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:183937:186369:1 gene:YIL095W transcript:YIL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRK1 description:Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton and reduces endocytic ability of cell through the phosphorylation of the Pan1p-Sla1p-End3p protein complex; PRK1 has a paralog, ARK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001357]</Hit_def>
  <Hit_accession>YIL095W</Hit_accession>
  <Hit_len>810</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>2.2194e-06</Hsp_evalue>
      <Hsp_query-from>1063</Hsp_query-from>
      <Hsp_query-to>1368</Hsp_query-to>
      <Hsp_hit-from>68</Hsp_hit-from>
      <Hsp_hit-to>179</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>114</Hsp_align-len>
      <Hsp_qseq>TIKETADEIKIFEGINHSNLVRYYGVELHRE------EMYIFMEYCDEGTLEEV--SRLG--LQEPVIRHYTKQICTAITELH--ERGIVHRDIKGANIFLTSTGHIKLGDFGC</Hsp_qseq>
      <Hsp_hseq>TLRAEVDAMKLLR--NNKHVVSYIDSHAARSVNGIAYEVFVLMEFCERGGLIDFMNTRLQNRLQESEILEIMSQTVQGITAMHALQPPLIHRDIKIENVLISHDGLYKVCDFGS</Hsp_hseq>
      <Hsp_midline>T++   D +K+    N+ ++V Y      R       E+++ ME+C+ G L +   +RL   LQE  I     Q    IT +H  +  ++HRDIK  N+ ++  G  K+ DFG </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>1020681815</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0035227-RA transcript Note:&quot;Similar to MAP3K4 Mitogen-activated protein kinase kinase kinase 4 (Homo sapiens)&quot; offset:520 AED:1.00 eAED:1.00 QI:520|0|0|0|0.33|0.23|13|1065|554</Iteration_query-def>
  <Iteration_query-len>3250</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2215747861</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0046131-RA transcript Note:&quot;Protein of unknown function&quot; offset:35 AED:0.61 eAED:0.61 QI:35|0.33|0|0.5|0|0|4|2|259</Iteration_query-def>
  <Iteration_query-len>814</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>88</Statistics_hsp-len>
      <Statistics_eff-space>426987861</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061289-RA transcript Note:&quot;Protein of unknown function&quot; offset:141 AED:0.15 eAED:0.15 QI:141|0.42|0.25|0.87|0.85|0.75|8|1025|181</Iteration_query-def>
  <Iteration_query-len>1712</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YMR223W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:716715:718130:1 gene:YMR223W transcript:YMR223W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBP8 description:Ubiquitin-specific protease component of the SAGA acetylation complex; required for SAGA (Spt-Ada-Gcn5-Acetyltransferase)-mediated deubiquitination of histone H2B [Source:SGD;Acc:S000004836]</Hit_def>
  <Hit_accession>YMR223W</Hit_accession>
  <Hit_len>471</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>5.57921e-09</Hsp_evalue>
      <Hsp_query-from>556</Hsp_query-from>
      <Hsp_query-to>1017</Hsp_query-to>
      <Hsp_hit-from>288</Hsp_hit-from>
      <Hsp_hit-to>465</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>74</Hsp_gaps>
      <Hsp_align-len>203</Hsp_align-len>
      <Hsp_qseq>VAPG--GPVQTLAEP----PLVPPDPGSLLGCLLRFTAPEQLTGSNKLL*GRKVRVYTEGTKRILVSSLPPVLTLHLKRFQQ-------------------------------------------YSLYGVVEHSGTMRGGHYTAYVKTXXXXXXXXXXXXQPGESDGSGRQQEGAWFYVSDSHVRTASLDQVLACQAYLLFY</Hsp_qseq>
      <Hsp_hseq>VCPGCQNNSKTTIDPFLDLSLDIKDKKKLYECLDSFHKKEQLKDFNYHC--GECNSTQDAIKQLGIHKLPSVLVLQLKRFEHLLNGSNRKLDDFIEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSHKGTVNEGHYIAFCKI-------------------SG----GQWFKFNDSMVSSISQEEVLKEQAYLLFY</Hsp_hseq>
      <Hsp_midline>V PG     +T  +P     L   D   L  CL  F   EQL   N      +     +  K++ +  LP VL L LKRF+                                            Y L G+V H GT+  GHY A+ K                    SG    G WF  +DS V + S ++VL  QAYLLFY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YJL197W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:63805:67569:1 gene:YJL197W transcript:YJL197W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBP12 description:Ubiquitin-specific protease; cleaves ubiquitin from ubiquitinated proteins; present in the nucleus and cytoplasm [Source:SGD;Acc:S000003733]</Hit_def>
  <Hit_accession>YJL197W</Hit_accession>
  <Hit_len>1254</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>3.70663e-06</Hsp_evalue>
      <Hsp_query-from>619</Hsp_query-from>
      <Hsp_query-to>1023</Hsp_query-to>
      <Hsp_hit-from>963</Hsp_hit-from>
      <Hsp_hit-to>1109</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>58</Hsp_gaps>
      <Hsp_align-len>170</Hsp_align-len>
      <Hsp_qseq>SLLGCLLRFTAPEQLTGSNKLL*GRKVRVYTEGTKRILVSSLPPVLTLHLKRFQQ-----------------------------------YSLYGVVEHSGTMRGGHYTAYVKTXXXXXXXXXXXXQPGESDGSGRQQEGAWFYVSDSHVRTASLDQVLACQAYLLFYER</Hsp_qseq>
      <Hsp_hseq>TLDDCLQLFSKPEILGLTDSWYCP-TCKEHRQATKQIQLWNTPDILLIHLKRFESQRSFSDKIDATVNFPITDLDLSRYVVYKDDPRGLIYDLYAVDNHYGGLGGGHYTAYVKNFA----------------------DNKWYYFDDSRVTETAPENSIAGSAYLLFYIR</Hsp_hseq>
      <Hsp_midline>+L  CL  F+ PE L  ++        + + + TK+I + + P +L +HLKRF+                                    Y LY V  H G + GGHYTAYVK                         +  W+Y  DS V   + +  +A  AYLLFY R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YER144C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:457806:460223:-1 gene:YER144C transcript:YER144C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBP5 description:Putative ubiquitin-specific protease; concentrates at the bud neck; UBP5 has a paralog, DOA4, that arose from the whole genome duplication [Source:SGD;Acc:S000000946]</Hit_def>
  <Hit_accession>YER144C</Hit_accession>
  <Hit_len>805</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.595</Hsp_bit-score>
      <Hsp_score>109</Hsp_score>
      <Hsp_evalue>9.59353e-06</Hsp_evalue>
      <Hsp_query-from>619</Hsp_query-from>
      <Hsp_query-to>1023</Hsp_query-to>
      <Hsp_hit-from>646</Hsp_hit-from>
      <Hsp_hit-to>803</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>69</Hsp_gaps>
      <Hsp_align-len>181</Hsp_align-len>
      <Hsp_qseq>SLLGCLLRFTAPEQLTGSNKLL*GRKVRVYTEGTKRILVSSLPPVLTLHLKRFQ---------------------------------------------QYSLYGVVEHSGTMRGGHYTAYVKTXXXXXXXXXXXXQPGESDGSGRQQEGAWFYVSDSHVRTASLD-QVLACQAYLLFYER</Hsp_qseq>
      <Hsp_hseq>NILDCFREFTKCERL-GVDEQWSCPKCLKKQPSTKQLKITRLPKKLIINLKRFDNQMNKNNVFVQYPYSLDLTPYWARDFNHEAIVNEDIPTRGQVPPFRYRLYGVACHSGSLYGGHYTSYVYK--------------GPKKG--------WYFFDDSLYRPITFSTEFITPSAYVLFYER</Hsp_hseq>
      <Hsp_midline>++L C   FT  E+L G ++     K       TK++ ++ LP  L ++LKRF                                              +Y LYGV  HSG++ GGHYT+YV                G   G        W++  DS  R  +   + +   AY+LFYER</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1086356825</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061296-RA transcript Note:&quot;Similar to Pacrg Parkin coregulated gene protein homolog (Mus musculus)&quot; offset:0 AED:0.29 eAED:0.31 QI:0|0.5|0.4|1|0.5|0.4|5|530|140</Iteration_query-def>
  <Iteration_query-len>953</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>526655209</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061297-RA transcript Note:&quot;Similar to Runx3 Runt-related transcription factor 3 (Mus musculus)&quot; offset:0 AED:0.35 eAED:0.35 QI:0|0|0|0.6|1|1|5|0|347</Iteration_query-def>
  <Iteration_query-len>1044</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>594561019</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0061299-RA transcript Note:&quot;Similar to OSTM1 Osteopetrosis-associated transmembrane protein 1 (Homo sapiens)&quot; offset:151 AED:0.38 eAED:0.42 QI:151|0.4|0.66|1|1|1|6|0|313</Iteration_query-def>
  <Iteration_query-len>1093</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>631576491</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0046140-RA transcript Note:&quot;Similar to Ccdc28b Coiled-coil domain-containing protein 28B (Mus musculus)&quot; offset:59 AED:0.41 eAED:0.41 QI:59|0.5|0.33|0.66|0.5|0.33|3|56|116</Iteration_query-def>
  <Iteration_query-len>466</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>82</Statistics_hsp-len>
      <Statistics_eff-space>173219291</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052614-RA transcript Note:&quot;Similar to OCLN Occludin (Homo sapiens)&quot; offset:27 AED:0.03 eAED:0.03 QI:27|0.4|0.5|1|0.6|0.66|6|2129|517</Iteration_query-def>
  <Iteration_query-len>3710</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2550875045</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052615-RA transcript Note:&quot;Similar to TUBGCP4 Gamma-tubulin complex component 4 (Homo sapiens)&quot; offset:1114 AED:0.23 eAED:0.23 QI:1114|0.70|0.72|0.88|0.64|0.72|18|0|511</Iteration_query-def>
  <Iteration_query-len>2650</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1779804595</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052619-RA transcript Note:&quot;Similar to DNASE1L3 Deoxyribonuclease gamma (Homo sapiens)&quot; offset:0 AED:0.38 eAED:0.38 QI:0|0|0.25|0.5|1|1|4|517|123</Iteration_query-def>
  <Iteration_query-len>889</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>89</Statistics_hsp-len>
      <Statistics_eff-space>481620069</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0026654-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0|0|6|0|505</Iteration_query-def>
  <Iteration_query-len>1518</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>944990804</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0007836-RA transcript Note:&quot;Similar to Ice2 Little elongation complex subunit 2 (Mus musculus)&quot; offset:1218 AED:0.18 eAED:0.20 QI:1218|0.53|0.57|1|0.30|0.5|14|1751|813</Iteration_query-def>
  <Iteration_query-len>5411</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>104</Statistics_hsp-len>
      <Statistics_eff-space>3784806233</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052622-RA transcript Note:&quot;Similar to CIAO2A Cytosolic iron-sulfur assembly component 2A (Homo sapiens)&quot; offset:69 AED:0.48 eAED:0.48 QI:69|0.5|0.66|0.66|1|1|3|0|78</Iteration_query-def>
  <Iteration_query-len>306</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YHR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:353625:354320:1 gene:YHR122W transcript:YHR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CIA2 description:Component of cytosolic iron-sulfur protein assembly (CIA) machinery; acts at a late step of Fe-S cluster assembly; forms the CIA targeting complex with Cia1p and Met18p that directs Fe-S cluster incorporation into a subset of proteins involved in methionine biosynthesis, DNA replication and repair, transcription, and telomere maintenance; ortholog of human FAM96B [Source:SGD;Acc:S000001164]</Hit_def>
  <Hit_accession>YHR122W</Hit_accession>
  <Hit_len>231</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>1.94321e-11</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>291</Hsp_query-to>
      <Hsp_hit-from>106</Hsp_hit-from>
      <Hsp_hit-to>169</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>41</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>69</Hsp_align-len>
      <Hsp_qseq>ALEVYDVIRTIQDPEKPSSLEELGVVSEGCVEVQALTEARRGEDEEEHLVVIRFTPTVPHCSLATLIAM</Hsp_qseq>
      <Hsp_hseq>AQEIYDLIAHISDPEHPLSLGQLSVVNLEDIDVHD-----SGNQNEMAEVVIKITPTITHCSLATLIGL</Hsp_hseq>
      <Hsp_midline>A E+YD+I  I DPE P SL +L VV+   ++V        G   E   VVI+ TPT+ HCSLATLI +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>72</Statistics_hsp-len>
      <Statistics_eff-space>73166010</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052623-RA transcript Note:&quot;Similar to CIAO2A Cytosolic iron-sulfur assembly component 2A (Homo sapiens)&quot; offset:0 AED:0.12 eAED:0.12 QI:0|0.66|0.75|0.75|0|0|4|1775|83</Iteration_query-def>
  <Iteration_query-len>2027</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YHR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:353625:354320:1 gene:YHR122W transcript:YHR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CIA2 description:Component of cytosolic iron-sulfur protein assembly (CIA) machinery; acts at a late step of Fe-S cluster assembly; forms the CIA targeting complex with Cia1p and Met18p that directs Fe-S cluster incorporation into a subset of proteins involved in methionine biosynthesis, DNA replication and repair, transcription, and telomere maintenance; ortholog of human FAM96B [Source:SGD;Acc:S000001164]</Hit_def>
  <Hit_accession>YHR122W</Hit_accession>
  <Hit_len>231</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>1.04073e-12</Hsp_evalue>
      <Hsp_query-from>55</Hsp_query-from>
      <Hsp_query-to>222</Hsp_query-to>
      <Hsp_hit-from>168</Hsp_hit-from>
      <Hsp_hit-to>223</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>43</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>56</Hsp_align-len>
      <Hsp_qseq>GLCLRVKLERCLPFKHKLEIYIAKGTHATEHEINKQINDKERIAAAMENPNLREIV</Hsp_qseq>
      <Hsp_hseq>GLGIRVRLERSLPPRFRITILLKKGTHDSENQVNKQLNDKERVAAACENEQLLGVV</Hsp_hseq>
      <Hsp_midline>GL +RV+LER LP + ++ I + KGTH +E+++NKQ+NDKER+AAA EN  L  +V</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1320390393</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

