<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0063546-RA transcript Note:&quot;Similar to PRPH Peripherin (Homo sapiens)&quot; offset:0 AED:0.48 eAED:0.70 QI:0|-1|0|1|-1|1|1|0|98</BlastOutput_query-def>
  <BlastOutput_query-len>297</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0063546-RA transcript Note:&quot;Similar to PRPH Peripherin (Homo sapiens)&quot; offset:0 AED:0.48 eAED:0.70 QI:0|-1|0|1|-1|1|1|0|98</Iteration_query-def>
  <Iteration_query-len>297</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>70</Statistics_hsp-len>
      <Statistics_eff-space>71109943</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0063547-RA transcript Note:&quot;Similar to DES Desmin (Canis lupus familiaris)&quot; offset:0 AED:0.46 eAED:0.47 QI:0|-1|0|1|-1|1|1|0|67</Iteration_query-def>
  <Iteration_query-len>204</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>41</Statistics_hsp-len>
      <Statistics_eff-space>71373609</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0038180-RA transcript Note:&quot;Similar to vim Vimentin (Cyprinus carpio)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0|0|2|0|167</Iteration_query-def>
  <Iteration_query-len>501</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>83</Statistics_hsp-len>
      <Statistics_eff-space>198766428</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0063486-RA transcript Note:&quot;Similar to Gp1bb Platelet glycoprotein Ib beta chain (Mus musculus)&quot; offset:0 AED:0.25 eAED:0.30 QI:0|0|0|0.5|1|1|2|0|258</Iteration_query-def>
  <Iteration_query-len>777</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>88</Statistics_hsp-len>
      <Statistics_eff-space>398988657</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0036793-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.25|0.2|5|0|292</Iteration_query-def>
  <Iteration_query-len>879</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>89</Statistics_hsp-len>
      <Statistics_eff-space>474640068</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0063487-RA transcript Note:&quot;Protein of unknown function&quot; offset:108 AED:0.31 eAED:0.37 QI:108|0|0.66|1|0.5|0.66|3|0|483</Iteration_query-def>
  <Iteration_query-len>1560</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>977102142</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0063718-RA transcript Note:&quot;Similar to Akap5 A-kinase anchor protein 5 (Mus musculus)&quot; offset:0 AED:0.27 eAED:1.00 QI:0|0|0|0.33|1|1|3|0|341</Iteration_query-def>
  <Iteration_query-len>1026</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>584656884</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0063719-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.87 eAED:0.87 QI:0|0|0|0.33|1|1|3|0|1151</Iteration_query-def>
  <Iteration_query-len>3456</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2371278484</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0048929-RA transcript Note:&quot;Similar to Kat8 Histone acetyltransferase KAT8 (Mus musculus)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0|0.5|2|0|72</Iteration_query-def>
  <Iteration_query-len>219</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YBL052C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:119379:121874:-1 gene:YBL052C transcript:YBL052C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAS3 description:Histone acetyltransferase catalytic subunit of NuA3 complex; acetylates histone H3, involved in transcriptional silencing; homolog of the mammalian MOZ proto-oncogene; mutant has aneuploidy tolerance; sas3gcn5 double mutation is lethal [Source:SGD;Acc:S000000148]</Hit_def>
  <Hit_accession>YBL052C</Hit_accession>
  <Hit_len>831</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>1.71319e-10</Hsp_evalue>
      <Hsp_query-from>37</Hsp_query-from>
      <Hsp_query-to>201</Hsp_query-to>
      <Hsp_hit-from>268</Hsp_hit-from>
      <Hsp_hit-to>319</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>33</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>55</Hsp_align-len>
      <Hsp_qseq>WITKVKYVDKIQVGRYEIDAWYFSPFPDEYGKQPRLWVCEFCLKYMKLETSYRMH</Hsp_qseq>
      <Hsp_hseq>WFSQIEY---IVLRNYEIKPWYTSPFPEHINQNKMVFICEFCLKYMTSRYTFYRH</Hsp_hseq>
      <Hsp_midline>W ++++Y   I +  YEI  WY SPFP+   +   +++CEFCLKYM    ++  H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YOR244W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:792531:793868:1 gene:YOR244W transcript:YOR244W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ESA1 description:Catalytic subunit of the histone acetyltransferase complex (NuA4); acetylates four conserved internal lysines of histone H4 N-terminal tail and can acetylate histone H2A; master regulator of cellular acetylation balance; required for cell cycle progression and transcriptional silencing at the rDNA locus and regulation of autophagy; human ortholog TIP60/KAT5 is implicated in cancer and other diseases, functionally complements lethality of the esa1 null mutation [Source:SGD;Acc:S000005770]</Hit_def>
  <Hit_accession>YOR244W</Hit_accession>
  <Hit_len>445</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.9802</Hsp_bit-score>
      <Hsp_score>110</Hsp_score>
      <Hsp_evalue>1.84875e-08</Hsp_evalue>
      <Hsp_query-from>34</Hsp_query-from>
      <Hsp_query-to>192</Hsp_query-to>
      <Hsp_hit-from>159</Hsp_hit-from>
      <Hsp_hit-to>211</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>18</Hsp_identity>
      <Hsp_positive>35</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>53</Hsp_align-len>
      <Hsp_qseq>HWITKVKYVDKIQVGRYEIDAWYFSPFPDEYGKQPRLWVCEFCLKYMKLETSY</Hsp_qseq>
      <Hsp_hseq>HEVARVRNLNRIIMGKYEIEPWYFSPYPIELTDEDFIYIDDFTLQYFGSKKQY</Hsp_hseq>
      <Hsp_midline>H + +V+ +++I +G+YEI+ WYFSP+P E   +  +++ +F L+Y   +  Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>45</Statistics_hsp-len>
      <Statistics_eff-space>73277876</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0047400-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0|0|3|0|259</Iteration_query-def>
  <Iteration_query-len>780</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>88</Statistics_hsp-len>
      <Statistics_eff-space>401321924</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0046402-RA transcript Note:&quot;Similar to RPL34 60S ribosomal protein L34 (Sus scrofa)&quot; offset:1477 AED:0.19 eAED:0.19 QI:1477|0.66|0.25|1|1|1|4|2937|110</Iteration_query-def>
  <Iteration_query-len>4747</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YIL052C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:256226:257063:-1 gene:YIL052C transcript:YIL052C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RPL34B description:Ribosomal 60S subunit protein L34B; homologous to mammalian ribosomal protein L34, no bacterial homolog; RPL34B has a paralog, RPL34A, that arose from the whole genome duplication [Source:SGD;Acc:S000001314]</Hit_def>
  <Hit_accession>YIL052C</Hit_accession>
  <Hit_len>121</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>105.145</Hsp_bit-score>
      <Hsp_score>261</Hsp_score>
      <Hsp_evalue>6.13704e-27</Hsp_evalue>
      <Hsp_query-from>1478</Hsp_query-from>
      <Hsp_query-to>1795</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>109</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>111</Hsp_align-len>
      <Hsp_qseq>MVQRLTYRRRLSYNTASNKTRLSKTPGGRLVYLYMKKVGKAPKSACGLCPGRLRGVKAVRPAVLKRLSKTKKHVSRAYGGSMCA-----KIKRAFLIEEQKIVVKVLKAQT</Hsp_qseq>
      <Hsp_hseq>MAQRVTFRRRNPYNTRSNKIKVVKTPGGILRAQHVKKLATRPK--CGDCGSALQGISTLRPRQYATVSKTHKTVSRAYGGSRCANCVKERIVRAFLIEEQKIVKKVVKEQT</Hsp_hseq>
      <Hsp_midline>M QR+T+RRR  YNT SNK ++ KTPGG L   ++KK+   PK  CG C   L+G+  +RP     +SKT K VSRAYGGS CA     +I RAFLIEEQKIV KV+K QT</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YER056C-A</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:269423:270185:-1 gene:YER056C-A transcript:YER056C-A_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RPL34A description:Ribosomal 60S subunit protein L34A; homologous to mammalian ribosomal protein L34, no bacterial homolog; RPL34A has a paralog, RPL34B, that arose from the whole genome duplication [Source:SGD;Acc:S000002135]</Hit_def>
  <Hit_accession>YER056C-A</Hit_accession>
  <Hit_len>121</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>105.145</Hsp_bit-score>
      <Hsp_score>261</Hsp_score>
      <Hsp_evalue>6.44215e-27</Hsp_evalue>
      <Hsp_query-from>1478</Hsp_query-from>
      <Hsp_query-to>1795</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>109</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>111</Hsp_align-len>
      <Hsp_qseq>MVQRLTYRRRLSYNTASNKTRLSKTPGGRLVYLYMKKVGKAPKSACGLCPGRLRGVKAVRPAVLKRLSKTKKHVSRAYGGSMCA-----KIKRAFLIEEQKIVVKVLKAQT</Hsp_qseq>
      <Hsp_hseq>MAQRVTFRRRNPYNTRSNKIKVVKTPGGILRAQHVKKLATRPK--CGDCGSALQGISTLRPRQYATVSKTHKTVSRAYGGSRCANCVKERIIRAFLIEEQKIVKKVVKEQT</Hsp_hseq>
      <Hsp_midline>M QR+T+RRR  YNT SNK ++ KTPGG L   ++KK+   PK  CG C   L+G+  +RP     +SKT K VSRAYGGS CA     +I RAFLIEEQKIV KV+K QT</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3304480893</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058878-RA transcript Note:&quot;Similar to MAPK10 Mitogen-activated protein kinase 10 (Homo sapiens)&quot; offset:0 AED:0.23 eAED:0.24 QI:0|0|0|0.61|1|1|13|0|499</Iteration_query-def>
  <Iteration_query-len>1500</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>245.358</Hsp_bit-score>
      <Hsp_score>625</Hsp_score>
      <Hsp_evalue>5.1597e-76</Hsp_evalue>
      <Hsp_query-from>154</Hsp_query-from>
      <Hsp_query-to>1194</Hsp_query-to>
      <Hsp_hit-from>8</Hsp_hit-from>
      <Hsp_hit-to>358</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>141</Hsp_identity>
      <Hsp_positive>215</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>370</Hsp_align-len>
      <Hsp_qseq>YSVEVGDSTFAVCKRYQNLRPVGSGAQGIVAAY---DTIIDRNVAIKKLSRPFQNQTHAKRAFRELVLMK---------CIIKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVIR--MELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAA-----TSFMMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRL-QPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHVWYDPAEVNGPSPQISDRRLDEREHTVD--EWKELIYKEVLDW</Hsp_qseq>
      <Hsp_hseq>HTFKVFNQDFSVDKRFQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGS---INGLYLYEELMECDMHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNA------------NSQALDLLEQMLAFDPQKRITVDEALEHPYLSIWHDPAD----EPVCSEKFEFSFESVNDMEDLKQMVIQEVQDF</Hsp_hseq>
      <Hsp_midline>++ +V +  F+V KR+Q ++ +G GA GIV +    +   D  VAIKK++  F      KR+ REL L++         C+  +  VF P  S      +YL  +LM+ ++ Q+I+    L         YQ+LCG+K++HSA ++HRDLKP N++V +DC LKI DFGLAR  +      S  +T YV TR+YRAPE++L   GYT+ +D+WS GCI+ E +  K +F G+DY++Q N++++ LGTP  E ++R+    V++Y+      P   F  L+P+A             SQA DLL +ML  DP KRITVDEAL+HPY+ +W+DPA+     P  S++     E   D  + K+++ +EV D+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>239.965</Hsp_bit-score>
      <Hsp_score>611</Hsp_score>
      <Hsp_evalue>1.63366e-74</Hsp_evalue>
      <Hsp_query-from>145</Hsp_query-from>
      <Hsp_query-to>1206</Hsp_query-to>
      <Hsp_hit-from>5</Hsp_hit-from>
      <Hsp_hit-to>347</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>141</Hsp_identity>
      <Hsp_positive>207</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>364</Hsp_align-len>
      <Hsp_qseq>QNFYSVEVGDSTFAVCKRYQNLRPVGSGAQGIV-AAYDTIIDRNVAIKKLSRPFQNQTHAKRAFRELVLMK-----CIIKLLNVF-SPQKSQEDFQDVYLVMDLMDANLCQVIRME-LDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRL-QPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHVWYDPAEVNGPSPQISDRRLDEREHTVDEWKELIYKEVLDWEDRG</Hsp_qseq>
      <Hsp_hseq>EEFIRTQIFGTVFEITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLSP------LEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ--MTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENTLKFVTSLPHRDPIPF------------SERFKTVEPDAVDLLEKMLVFDPKKRITAADALAHPYSAPYHDPTDEPVADAKF-DWHFNDADLPVDTWRVMMYSEILDFHKIG</Hsp_hseq>
      <Hsp_midline>+ F   ++  + F +  RY +L PVG GA G+V +A DT+  + VAIKK+ +PF     AKR +REL L+K      +I L ++F SP       +D+Y V +L   +L ++++   L+ + + Y LYQ+L G+K++HSAG+IHRDLKPSNI++  +C LKI DFGLAR       MT YV TRYYRAPE++L    Y   VDIWS GCI  EM+  K LFPG+D++ Q++ + + LG+P  + +  +       +V + P      F            SE  K     A DLL +MLV DP KRIT  +AL HPY   ++DP +      +  D   ++ +  VD W+ ++Y E+LD+   G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>211.075</Hsp_bit-score>
      <Hsp_score>536</Hsp_score>
      <Hsp_evalue>2.33148e-64</Hsp_evalue>
      <Hsp_query-from>178</Hsp_query-from>
      <Hsp_query-to>1188</Hsp_query-to>
      <Hsp_hit-from>6</Hsp_hit-from>
      <Hsp_hit-to>352</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>135</Hsp_identity>
      <Hsp_positive>191</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>361</Hsp_align-len>
      <Hsp_qseq>TFAVCKRYQNLRPVGSGAQGIV-AAYDTIIDRNVAIKKLSRPFQNQTHAKRAFRELVLMK-----CIIKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVIRME-LDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFM-----------MTPYVVTRYYRAPEVIL-GMGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRL--QPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHVWYDPA-EVNGPSPQISDRRLDEREH--TVDEWKELIYKEVL</Hsp_qseq>
      <Hsp_hseq>VYNISSDFQLKSLLGEGAYGVVCSATHKPTGEIVAIKKIE-PFDKPLFALRTLREIKILKHFKHENIITIFNIQRPD-SFENFNEVYIIQELMQTDLHRVISTQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHSDNDLRCIESPRAREYIKSLPMYPAAPLEKMFPRV------------NPKGIDLLQRMLVFDPAKRITAKEALEHPYLQTYHDPNDEPEGEPIPPSFFEFDHYKEALTTKDLKKLIWNEIF</Hsp_hseq>
      <Hsp_midline> + +   +Q    +G GA G+V +A        VAIKK+  PF     A R  RE+ ++K      II + N+  P  S E+F +VY++ +LM  +L +VI  + L  + I Y +YQ L  +K LH + +IHRDLKPSN+++ S+C LK+ DFGLAR    S             MT YV TR+YRAPEV+L    Y+  +D+WS GCI+ E+   + +FPGRDY  Q   +   +GTP S+   R    P  R Y+++ P YP    EK+FP                +  DLL RMLV DP KRIT  EAL+HPY+  ++DP  E  G     S    D  +   T  + K+LI+ E+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>201.06</Hsp_bit-score>
      <Hsp_score>510</Hsp_score>
      <Hsp_evalue>1.07698e-59</Hsp_evalue>
      <Hsp_query-from>181</Hsp_query-from>
      <Hsp_query-to>1194</Hsp_query-to>
      <Hsp_hit-from>17</Hsp_hit-from>
      <Hsp_hit-to>358</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>125</Hsp_identity>
      <Hsp_positive>196</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>360</Hsp_align-len>
      <Hsp_qseq>FAVCKRYQNLRPVGSGAQGIVAAYDTIIDRN----VAIKKLSRPFQNQTHAKRAFRELVLMK------CIIKLLN---VFSPQKSQEDFQDVYLVMDLMDANLCQVIRME--LDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSF-----MMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQP-TVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHVWYDPAEVNGPSPQISDRRLDEREHTVDEWKELIYKEVLDW</Hsp_qseq>
      <Hsp_hseq>FILNKHFHLTGKIGRGSHSLICS-STYTESNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGA---LNGVYLYEELMECDLSQIIRSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIPGRSFESILPGA------------NPEALELLKKMLEFDPKKRITVEDALEHPYLSMWHDIDE--EFSCQKTFRFEFEHIESMAELGNEVIKEVFDF</Hsp_hseq>
      <Hsp_midline>F + K +     +G G+  ++ +  T  + N    VAI+K+   F N+   KR  REL L++       I+ L +   VF P  +      VYL  +LM+ +L Q+IR E  L+       +YQ+LC +K++HSA ++H DLKP N++V SDC LKI +FGL+ + + +       +  Y+ + +Y+APE++L     T+ VDIWS GCI+ E++  K +F G+DY+D  N +++ LGTP  E ++ +    V NY+      PG SFE + P A              +A +LL +ML  DP KRITV++AL+HPY+ +W+D  E    S Q + R   E   ++ E    + KEV D+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>196.438</Hsp_bit-score>
      <Hsp_score>498</Hsp_score>
      <Hsp_evalue>1.44654e-58</Hsp_evalue>
      <Hsp_query-from>178</Hsp_query-from>
      <Hsp_query-to>1092</Hsp_query-to>
      <Hsp_hit-from>6</Hsp_hit-from>
      <Hsp_hit-to>321</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>124</Hsp_identity>
      <Hsp_positive>182</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>328</Hsp_align-len>
      <Hsp_qseq>TFAVCKRYQNLRPVGSGAQGIV-AAYDTIIDRNVAIKKLSRPFQNQTHAKRAFRELVLMK------CIIKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVIRME------LDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSF--------MMTPYVVTRYYRAPEVILGMG-YTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPT-VRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHVWYDPAE</Hsp_qseq>
      <Hsp_hseq>TFDIPSQYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKI-QPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPV-SIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIANLPMRPPLPWETVWSKTDLNPD----------MIDLLDKMLQFNPDKRISAAEALRHPYLAMYHDPSD</Hsp_hseq>
      <Hsp_midline>TF +  +Y+ +  +G GA G V +A        VAIKK+ +PF  +    R  RE+ L++       II +L+   P  S +    VYLV +LM+ +L +VI  +      L  + + Y  YQ+L  +K +HSA +IHRD+KPSN+++ S+C LK+ DFGLAR  A+S          MT YV TR+YRAPE++L    YT  +DIWS GCI+ EMV  K LFPGRDY  Q   ++E LGTP  E   +++    + Y+   P  P   +E ++       D            DLL +ML  +P KRI+  EAL+HPY+ +++DP++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>167.162</Hsp_bit-score>
      <Hsp_score>422</Hsp_score>
      <Hsp_evalue>1.97311e-47</Hsp_evalue>
      <Hsp_query-from>199</Hsp_query-from>
      <Hsp_query-to>1170</Hsp_query-to>
      <Hsp_hit-from>38</Hsp_hit-from>
      <Hsp_hit-to>379</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>117</Hsp_identity>
      <Hsp_positive>186</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>358</Hsp_align-len>
      <Hsp_qseq>YQNLRPVGSGAQGIVAAYDTIIDRN----VAIKKLSRPFQNQTHAKRAFRELVLM------KCIIKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVIR--MELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFM---------MTPYVVTRYYRAPEVIL-GMGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNY----VETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHVWYDPAE----VNGPSPQISDRRLDE----REHTVDEWKEL</Hsp_qseq>
      <Hsp_hseq>YEIIQFLGKGAYGTVCSVK-FKGRSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGHKNIVNLIDLEIVTSSPYD--GLYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDKDILIKFG-TIKAWNLGKNSNNPVYKKIPWSNIFPFA------------SHEAINLIESLLHWDSTHRLNVEQAISHPFLNEVRKPDDEPVCLQGPFDFTYESELNSMSKLRDYLVEEVKNF</Hsp_hseq>
      <Hsp_midline>Y+ ++ +G GA G V +      R+    +A+KK+S  F  +   KRA REL  M      K I+ L+++     S  D   +Y   +L+D +L +VI   ++L    I Y LYQ+LCG+K++HSA +IHRDLKP NI+   +  LKI DFGLAR     F          +T YV TR+YRAPE++L    Y+++VDIW+VGCI+ E    K +F GRD + Q  ++I+ LGTP  + + +   T++ +        P Y    +  +FP A            + +A +L+  +L  D   R+ V++A+ HP+++    P +    + GP     +  L+     R++ V+E K  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>140.198</Hsp_bit-score>
      <Hsp_score>352</Hsp_score>
      <Hsp_evalue>2.40952e-38</Hsp_evalue>
      <Hsp_query-from>118</Hsp_query-from>
      <Hsp_query-to>1071</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>296</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>105</Hsp_identity>
      <Hsp_positive>160</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>331</Hsp_align-len>
      <Hsp_qseq>MSGRPVQEPQNFYSVE-VGDSTFAVCKRYQNLRPVGSGAQGIVAAYDTIIDRNVAIKKLSRPFQNQTHAKRAFRELVLMK-----CIIKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVIR-----MELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSF-MMTPYVVTRYYRAPEVIL-GMGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIH</Hsp_qseq>
      <Hsp_hseq>MSG----ELANYKRLEKVGEGTYGVVYKALDLRP----GQG---------QRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIV-----HSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTP----NEAIWPDIVYLPDFKPSFPQWRRKDL---------SQVVPSLDPRGIDLLDKLLAYDPINRISARRAAIHPYFQ</Hsp_hseq>
      <Hsp_midline>MSG    E  N+  +E VG+ T+ V  +  +LRP     QG          R VA+KK+    +++     A RE+ L+K      I++L ++        D   +YLV + +D +L + +        L  + +   + Q+  GI + HS  I+HRDLKP N+++  D +LK+ DFGLAR         T  +VT +YRAPEV+L G  Y+  VD WS+GCI  EM   K +F G   IDQ  K+   LGTP     + + P +    + +P +P +  + L         S+       +  DLL ++L  DP+ RI+   A  HPY  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>133.65</Hsp_bit-score>
      <Hsp_score>335</Hsp_score>
      <Hsp_evalue>2.50296e-35</Hsp_evalue>
      <Hsp_query-from>217</Hsp_query-from>
      <Hsp_query-to>1140</Hsp_query-to>
      <Hsp_hit-from>45</Hsp_hit-from>
      <Hsp_hit-to>347</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>107</Hsp_identity>
      <Hsp_positive>168</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>329</Hsp_align-len>
      <Hsp_qseq>VGSGAQGIVAAYDTII---DRNVAIKKL--SRPFQNQTHAKRAFRELVLMKC-----IIKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVIRMELDHER-------ISYLLYQMLCGIKHLHS-AGIIHRDLKPSNIVVKSDC-SLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYI-HVWYDPAEVNGPSPQISDRRLDER</Hsp_qseq>
      <Hsp_hseq>VGHGSFGVVFA--TVIQETNEKVAIKKVLQDKRFKN--------RELEIMKMLSHINIIDLKYFFYERDSQDEIY-LNLILEYMPQSLYQRLR-HFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILGTPSKQEICSMNP---NYME-------HKFPQIKPIPL----SRVFKKEDDQTVEFLADVLKYDPLERFNALQCLCSPYFDELKLDDGKINQITTDLKLLEFDEN</Hsp_hseq>
      <Hsp_midline>VG G+ G+V A  T+I   +  VAIKK+   + F+N        REL +MK      II L   F  + SQ++   + L+++ M  +L Q +R    H+R       I Y ++Q+   + +LH  A + HRD+KP N++V  +  SLK+ DFG A+    +     Y+ +RYYRAPE+I G   YT  +DIWS GC+M E++  + +FPG   IDQ  ++I+ LGTP  + +  + P   NY+E       + F ++ P  L    S   K +  Q  + L+ +L  DPL+R    + L  PY   +  D  ++N  +  +     DE </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>133.265</Hsp_bit-score>
      <Hsp_score>334</Hsp_score>
      <Hsp_evalue>4.75607e-35</Hsp_evalue>
      <Hsp_query-from>121</Hsp_query-from>
      <Hsp_query-to>1071</Hsp_query-to>
      <Hsp_hit-from>7</Hsp_hit-from>
      <Hsp_hit-to>328</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>103</Hsp_identity>
      <Hsp_positive>169</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>344</Hsp_align-len>
      <Hsp_qseq>SGRPVQEPQNFYSVEVGDSTFAVCKRY--QNLRPVGSGAQG-IVAAYDTIIDRN----VAIKKLSRPFQNQTHAKRAFRELVLMKC-----IIKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVI------RMELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCS-LKILDFGLARTAATSFMMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYS---FEKLF----PDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIH</Hsp_qseq>
      <Hsp_hseq>NGVPLQRGSEFIADDVTSNKSNNTRRMLVKEYRKIGRGAFGTVVQAYLTQDKKNWLGPFAIKKVP------AHTEYKSRELQILRIADHPNIVKLQYFFTHLSPQDNKVYQHLAMECLPETLQIEINRYVTNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSISYICSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLREIAKLLGPPDKRFIFFSNPAYDGPLFSKPLFSGSSQQRFEKYFGHSGPDGI----------------DLLMKILVYEPQQRLSPRRILAHQFFN</Hsp_hseq>
      <Hsp_midline>+G P+Q    F + +V  +     +R   +  R +G GA G +V AY T   +N     AIKK+        H +   REL +++      I+KL   F+    Q++    +L M+ +   L   I      ++E+  + I    YQ+  G+ +LH  G+ HRD+KPSN++V  +   LKI DFG A+    +     Y+ +R+YRAPE+I+G   YT  +DIW +GC+MGEM+  K +F G++ + Q  ++ + LG P   F+    P     + ++P + G S   FEK F    PD +                DLL ++LV +P +R++    L H + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>130.183</Hsp_bit-score>
      <Hsp_score>326</Hsp_score>
      <Hsp_evalue>8.9214e-33</Hsp_evalue>
      <Hsp_query-from>199</Hsp_query-from>
      <Hsp_query-to>1185</Hsp_query-to>
      <Hsp_hit-from>60</Hsp_hit-from>
      <Hsp_hit-to>399</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>111</Hsp_identity>
      <Hsp_positive>170</Hsp_positive>
      <Hsp_gaps>71</Hsp_gaps>
      <Hsp_align-len>370</Hsp_align-len>
      <Hsp_qseq>YQNLRPVGSGAQGIVAAYDTI---IDRNVAIKKLSRPFQNQTHAKRAFRELVLMK-----CIIKLLNVF---SPQ----KSQEDFQDVYLVMDLMDANLCQVI---RMELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLAR-------------TAATSFMMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSE------FMKRLQPTVRNYVET-RPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHVWY--DPAEVNGPSPQISDRRLDEREHTVDEWKELIYKEV</Hsp_qseq>
      <Hsp_hseq>YREDEKLGQGTFGEV--YKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTEEDWAVARYLPGAELTTTNYKPTLRERFGKYLSE--------------------TGLDFLGQLLALDPYKRLTAMSAKHHP----WFKEDPL----PSEKITLPTEESHEADIKRYKEEMHQSL</Hsp_hseq>
      <Hsp_midline>Y+    +G G  G V  Y  I     R VA+KK+    +       A RE+ ++K      IIKL+ +    SP      S    +  Y+++  M A+L  V+   R+ L+   I  ++ Q+L G+ ++H A  +HRD+K +NI++  +  LK+ DFGLAR              A +    T  VVTR+YRAPE++LG   YT  VDIW VGC+  E    K +  G+  IDQ + + + LGTP  E      ++   + T  NY  T R R+  Y  E                       D L ++L +DP KR+T   A  HP    W+  DP     PS +I+    +  E  +  +KE +++ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>120.939</Hsp_bit-score>
      <Hsp_score>302</Hsp_score>
      <Hsp_evalue>2.71006e-31</Hsp_evalue>
      <Hsp_query-from>196</Hsp_query-from>
      <Hsp_query-to>1089</Hsp_query-to>
      <Hsp_hit-from>6</Hsp_hit-from>
      <Hsp_hit-to>304</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>93</Hsp_identity>
      <Hsp_positive>151</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>318</Hsp_align-len>
      <Hsp_qseq>RYQNLRPVGSGAQGIV-AAYDTIIDRNVAIKKLSRPFQNQTHAKRAFRELVLMK-----CIIKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVIRME--------LDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSF-MMTPYVVTRYYRAPEVILGM-GYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRP----RYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHVWYDPA</Hsp_qseq>
      <Hsp_hseq>QFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHENIVRLYDVIHTENK------LTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTP----NESLWPSVTKLPKYNPNIQQRPPRDLRQVLQPHTKEPLD--------GNLMDFLHGLLQLNPDMRLSAKQALHHPWFAEYYHHA</Hsp_hseq>
      <Hsp_midline>+++ L  +G+G    V    +      VA+K++    +  T +  A RE+ LMK      I++L +V   +        + LV + MD +L + +           L+   + Y  +Q+L G+   H   I+HRDLKP N+++     LK+ DFGLAR         +  VVT +YRAP+V++G   Y+ ++DIWS GCI+ EM+  K LFPG +  +Q   + + +GTP     + L P+V    +  P    R P    + L P    P D            D L  +L ++P  R++  +AL HP+   +Y  A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>120.553</Hsp_bit-score>
      <Hsp_score>301</Hsp_score>
      <Hsp_evalue>8.35065e-30</Hsp_evalue>
      <Hsp_query-from>199</Hsp_query-from>
      <Hsp_query-to>1068</Hsp_query-to>
      <Hsp_hit-from>183</Hsp_hit-from>
      <Hsp_hit-to>469</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>94</Hsp_identity>
      <Hsp_positive>147</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>313</Hsp_align-len>
      <Hsp_qseq>YQNLRPVGSGAQGIV-AAYDTIIDRNVAIKKLSRPFQNQTHAKRAFRELVLMKCIIKLLNVFS-PQKSQ------EDFQDVYLVMDLMDANLCQVI---RMELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSE-----------FMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYI</Hsp_qseq>
      <Hsp_hseq>YLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIRE-------IKLLQSFDHPNVSTIKEIMVESQKTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKMNSRADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTPTINSWPTLYDMPWFFMIMPQQTTK-YVN--------NFSEKF----------KSVLPSSKCLQLAINLLCYDQTKRFSATEALQSDYF</Hsp_hseq>
      <Hsp_midline>Y  +  VG G  G V  A +T  ++ VA+KKL    + +     + RE       IKLL  F  P  S       E  + VY++ +  D +L  ++    +++ H +  +L  Q+L G+++LH   I+HRD+K SNI++ +  +LKI DFGLAR   +    T  V+T +YR PE++LG   Y   VD+W  GC++ E+     +F G + ++Q   + + +GTP              FM   Q T + YV         +F + F           S L +S+   L   +L  D  KR +  EALQ  Y </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>114.39</Hsp_bit-score>
      <Hsp_score>285</Hsp_score>
      <Hsp_evalue>5.33261e-29</Hsp_evalue>
      <Hsp_query-from>187</Hsp_query-from>
      <Hsp_query-to>1065</Hsp_query-to>
      <Hsp_hit-from>3</Hsp_hit-from>
      <Hsp_hit-to>289</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>92</Hsp_identity>
      <Hsp_positive>148</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>307</Hsp_align-len>
      <Hsp_qseq>VCKRYQNLRPVGSGAQGIV-AAYDTIIDRNVAIKKLSRPFQNQTHAKRAFRELVLMK-----CIIKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVIR---MELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLART-AATSFMMTPYVVTRYYRAPEVILGMG-YTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSK--LKASQ-ARDLLSRMLVIDPLKRITVDEALQHPY</Hsp_qseq>
      <Hsp_hseq>VNMEYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNVIELIDIFMA------YDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTD----RDWPEVSSFMT-------YNKLQIYPP---PSRDELRKRFIAASEYALDFMCGMLTMNPQKRWTAVQCLESDY</Hsp_hseq>
      <Hsp_midline>V   Y   + VG G   +V         R +AIK++            A RE+  ++      +I+L+++F        + ++ LV++ +  +L  VI+   +      I   +   L G+ H H   I+HRDLKP+N++   D  +K+ DFGLAR   A   ++T  VVTR+YRAPE++ G   YT  +DIWSVG I  E++      PG++ +DQ       LGTP      R  P V +++        Y+  +++P    P+  E  K  + AS+ A D +  ML ++P KR T  + L+  Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YDL079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:312951:314748:-1 gene:YDL079C transcript:YDL079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRK1 description:Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication [Source:SGD;Acc:S000002237]</Hit_def>
  <Hit_accession>YDL079C</Hit_accession>
  <Hit_len>501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>116.316</Hsp_bit-score>
      <Hsp_score>290</Hsp_score>
      <Hsp_evalue>1.90916e-28</Hsp_evalue>
      <Hsp_query-from>199</Hsp_query-from>
      <Hsp_query-to>1065</Hsp_query-to>
      <Hsp_hit-from>164</Hsp_hit-from>
      <Hsp_hit-to>446</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>94</Hsp_identity>
      <Hsp_positive>146</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>308</Hsp_align-len>
      <Hsp_qseq>YQNLRPVGSGAQGIVAAYDTIIDRN--VAIKKL--SRPFQNQTHAKRAFRELVLMKCIIK----LLNVFSPQKSQEDFQDVYLVMDLMDANLCQVIR------MELDHERISYLLYQMLCGIKHLHSA-GIIHRDLKPSNIVVK-SDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYV--ETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPY</Hsp_qseq>
      <Hsp_hseq>YPTTEVVGHGSFGVVVT-TVIIETNQKVAIKKVLQDRRYKN--------RELETMKMLCHPNTVGLQYYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKIMGIPTKDEISGMNPNYEDHVFPNIKPITLAEIFKAEDPDTL----------------DLLTKTLKYHPCERLVPLQCLLSSY</Hsp_hseq>
      <Hsp_midline>Y     VG G+ G+V     II+ N  VAIKK+   R ++N        REL  MK +       L  +  +K +ED   + LV+D M  +L Q +R      M++    I +  YQ+   + +LH+   I HRD+KP N++V  +  S KI DFG A+          Y+ +RYYRAPE++ G   Y+  VD+WS  C++ E++  K LF G   IDQ  ++I+ +G P  + +  + P   ++V    +P      F+   PD L                DLL++ L   P +R+   + L   Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>115.931</Hsp_bit-score>
      <Hsp_score>289</Hsp_score>
      <Hsp_evalue>3.31227e-28</Hsp_evalue>
      <Hsp_query-from>319</Hsp_query-from>
      <Hsp_query-to>1068</Hsp_query-to>
      <Hsp_hit-from>201</Hsp_hit-from>
      <Hsp_hit-to>463</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>89</Hsp_identity>
      <Hsp_positive>140</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>279</Hsp_align-len>
      <Hsp_qseq>AKRAFRELVLM-----KCIIKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVIRMELDHER-------ISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLART----AATSFMMTPYVVTRYYRAPEVILGM-GYTENVDIWSVGCIMGEMVRHKILFPGRD-----------YIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSK-LKASQARDLLSRMLVIDPLKRITVDEALQHPYI</Hsp_qseq>
      <Hsp_hseq>SQSACREMALCRELHNKHLTTLVEIFLERKC------VHMVYEYAEHDLLQIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDGCVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELIGLQPIFKGEEAKLDSKKTVPFQVNQLQRILEVLGTPD----QKIWP----YLEKYPEYDQITKFPKYRDNL--ATWYHSAGGRDKHALSLLYHLLNYDPIKRIDAFNALEHKYF</Hsp_hseq>
      <Hsp_midline>++ A RE+ L      K +  L+ +F  +K       V++V +  + +L Q+I      E+       +  +++Q+L G+ +LH   ++HRDLKP+NI+V  D  +KI D GLAR       T +     VVT +YRAPE++LG   YT  VD+WSVGCI  E++  + +F G +            ++Q  +++E LGTP     +++ P    Y+E  P Y   +    + D L  A   HS   +   A  LL  +L  DP+KRI    AL+H Y </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>116.316</Hsp_bit-score>
      <Hsp_score>290</Hsp_score>
      <Hsp_evalue>4.05949e-28</Hsp_evalue>
      <Hsp_query-from>223</Hsp_query-from>
      <Hsp_query-to>840</Hsp_query-to>
      <Hsp_hit-from>81</Hsp_hit-from>
      <Hsp_hit-to>305</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>120</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>232</Hsp_align-len>
      <Hsp_qseq>SGAQGIVAAYDTIIDRNVAIKKLSRPFQNQTHAKRAFRELVLMKCIIKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVIRMELDHER--------ISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVV-----------------KSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMGY-TENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPV</Hsp_qseq>
      <Hsp_hseq>NGHQNYITKTQGVVAIKTMMTKL-HTLQDYTRV-REIKFILAIPANDHLIQIFEVFIDSENYQ-LHIVMECMEQNLYQMMK----HRRRRVFSIPSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVENKNPYTAYVSTRWYRSPEILLRSGYYSKPLDIWAFGCVAVEVTVFRALFPGANEIDQIWKILEVLGTPI</Hsp_hseq>
      <Hsp_midline>+G Q  +     ++     + KL    Q+ T   R  + ++ +     L+ +F      E++Q +++VM+ M+ NL Q+++    H R        +  +L Q+L G+KH+H     HRDLKP NI++                 + +  +K+ DFGLAR        T YV TR+YR+PE++L  GY ++ +DIW+ GC+  E+   + LFPG + IDQ  K++E LGTP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>108.227</Hsp_bit-score>
      <Hsp_score>269</Hsp_score>
      <Hsp_evalue>2.48852e-25</Hsp_evalue>
      <Hsp_query-from>421</Hsp_query-from>
      <Hsp_query-to>1146</Hsp_query-to>
      <Hsp_hit-from>447</Hsp_hit-from>
      <Hsp_hit-to>737</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>88</Hsp_identity>
      <Hsp_positive>147</Hsp_positive>
      <Hsp_gaps>63</Hsp_gaps>
      <Hsp_align-len>298</Hsp_align-len>
      <Hsp_qseq>LVMDLMDANLCQVIRMELDH----ERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS--DCSLKILDFGL----ARTAATSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVS----------EFMKRLQPT-----------------VRNY-VETRPRYPGYSFEKLFPDAL----FPADSEHSKL---KASQARD----LLSRMLVIDPLKRITVDEALQHPYIHV------WYDP-AEVNGPSPQISDRRLDEREH</Hsp_qseq>
      <Hsp_hseq>LVFELLSNNLYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPELKIIDFGSSCEEARTVYT------YIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAELFLGIPIFPGASEYNQLTRIIDTLGYPPSWMIDMGKNSGKFMKKLAPEESSSSTQKHRMKTIEEFCREYNIVEKPSKQYFKWRKL-PDIIRNYRYPKSIQNSQELIDQEMQNRECLIHFLGGVLNLNPLERWTPQQAMLHPFITKQEFTGEWFPPGSSLPGPSEKHDDAKGQQSEY</Hsp_hseq>
      <Hsp_midline>LV +L+  NL ++++    H    + I     Q+L  +  L  + +IH DLKP NI++ +     LKI+DFG     ART  T      Y+ +R+YRAPE+ILG+ Y+ ++D+WS+GCI+ E+     +FPG    +Q  ++I+ LG P S          +FMK+L P                   R Y +  +P    + + KL PD +    +P   ++S+    +  Q R+     L  +L ++PL+R T  +A+ HP+I        W+ P + + GPS +  D +  + E+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YOR061W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:441534:442553:1 gene:YOR061W transcript:YOR061W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA2 description:Alpha&apos; catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000005587]</Hit_def>
  <Hit_accession>YOR061W</Hit_accession>
  <Hit_len>339</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>92.4337</Hsp_bit-score>
      <Hsp_score>228</Hsp_score>
      <Hsp_evalue>5.09524e-21</Hsp_evalue>
      <Hsp_query-from>136</Hsp_query-from>
      <Hsp_query-to>1068</Hsp_query-to>
      <Hsp_hit-from>28</Hsp_hit-from>
      <Hsp_hit-to>334</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>145</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>327</Hsp_align-len>
      <Hsp_qseq>QEPQNFYSVEVGDST-FAVCKRYQNLRPVGSGAQGIVAAYDTIIDRNVAIKKLSRPFQNQTHAKRAFRELVLMKCIIKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVIRMELDH------------ERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVK-SDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMG-YTENVDIWSVGCIMGEMV-RHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYI</Hsp_qseq>
      <Hsp_hseq>ERPQEYWDYEQGVTIDWGKISNYEIINKIGRGKYSEVFSGRCIVNNQKCVIKVLKPVK----MKKIYRELKILTNLTGGPNVVG----------LYDIVQDADSKIPALIFEEIKNVDFRTLYPTFKLPDIQYYFTQLLIALDYCHSMGIMHRDVKPQNVMIDPTERKLRLIDWGLAEFYHPGVDYNVRVASRYHKGPELLVNLNQYDYSLDLWSVGCMLAAIVFKKEPFFKGSSNPDQLVKIATVLGT------KELLGYLGKYGLHLPSEYDNIMRDFTKKSWTHFITSETKLAVPEVVDLIDNLLRYDHQERLTAKEAMDHKFF</Hsp_hseq>
      <Hsp_midline>+ PQ ++  E G +  +     Y+ +  +G G    V +   I++    + K+ +P +     K+ +REL ++  +    NV            +Y ++   D+ +  +I  E+ +              I Y   Q+L  + + HS GI+HRD+KP N+++  ++  L+++D+GLA            V +RY++ PE+++ +  Y  ++D+WSVGC++  +V + +  F G    DQ  K+   LGT      K L   +  Y    P             +     +  +KL   +  DL+  +L  D  +R+T  EA+ H + </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>91.2781</Hsp_bit-score>
      <Hsp_score>225</Hsp_score>
      <Hsp_evalue>1.76276e-20</Hsp_evalue>
      <Hsp_query-from>421</Hsp_query-from>
      <Hsp_query-to>945</Hsp_query-to>
      <Hsp_hit-from>122</Hsp_hit-from>
      <Hsp_hit-to>300</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>186</Hsp_align-len>
      <Hsp_qseq>LVMDLMDANLCQVIRMELDH------ERISYLLYQMLCGIKHLHSAGIIHRDLKPSNI-VVKSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKL---FPDALF</Hsp_qseq>
      <Hsp_hseq>FVMEYIPQTLSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGIAKVCDFGSAQRLDDNTELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPLFKG----DSANSQLEEIAKLLGRFPK---SSIKNSQELQDSLNDQKFKKFMHWFPSIEF</Hsp_hseq>
      <Hsp_midline> VM+ +   L   I    D+      + I    +Q+L  +  LHS  I H DLKPSNI ++ S    K+ DFG A+    +  +  Y  +R+YRAPE++L    YT  +DIWS+GCI+GEM++ + LF G    D  N  +E++   +  F K    +++N  E +       F+K    FP   F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.8929</Hsp_bit-score>
      <Hsp_score>224</Hsp_score>
      <Hsp_evalue>1.12129e-19</Hsp_evalue>
      <Hsp_query-from>334</Hsp_query-from>
      <Hsp_query-to>1077</Hsp_query-to>
      <Hsp_hit-from>76</Hsp_hit-from>
      <Hsp_hit-to>288</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>254</Hsp_align-len>
      <Hsp_qseq>RELVLMKCIIKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVIRMELDH----ERISYLLY-QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMGYTE-NVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHVW</Hsp_qseq>
      <Hsp_hseq>REIVIMK-LLSHPNVLSLYDVWETNNNLYLILEY--AEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILF------ALLTGRLPFDEENGNVRDLLLKVQKGQ---------------------FE-------MPNDTEISR----DAQDLIGKILVVDPRQRIKIRDILSHPLLKKY</Hsp_hseq>
      <Hsp_midline>RE+V+MK ++   NV S     E   ++YL+++   A   ++  + +DH    ER +   + Q++ GI + H+ GI+HRDLKP N+++ S  ++KI DFG+A     + ++     + +Y APE++ G+ Y     D+WS G I+        L  GR   D+ N  +  L   V +                       FE        P D+E S+     A+DL+ ++LV+DP +RI + + L HP +  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YIL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:287790:288908:-1 gene:YIL035C transcript:YIL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA1 description:Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000001297]</Hit_def>
  <Hit_accession>YIL035C</Hit_accession>
  <Hit_len>372</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.5817</Hsp_bit-score>
      <Hsp_score>218</Hsp_score>
      <Hsp_evalue>1.12219e-19</Hsp_evalue>
      <Hsp_query-from>421</Hsp_query-from>
      <Hsp_query-to>1086</Hsp_query-to>
      <Hsp_hit-from>150</Hsp_hit-from>
      <Hsp_hit-to>365</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>227</Hsp_align-len>
      <Hsp_qseq>LVMDLMDANLCQVIRMELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVV-KSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMG-YTENVDIWSVGCIMGEMV-RHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLF--PDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHVWYDP</Hsp_qseq>
      <Hsp_hseq>LVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGT--SDFEKYLL----KYEITLPR-EFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHP----WFAP</Hsp_hseq>
      <Hsp_midline>LV + +D    +++  +L    I + ++++L  + + HS GI+HRD+KP N+++   +  L+++D+GLA     +      V +R+++ PE+++    Y  ++D+WS G ++  M+ + +  F G    DQ  K+++ LGT  S+F K L      Y  T PR   Y  ++    P   F  D         +  DL+  +L  D  +R+T  EA+ HP    W+ P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>89.7373</Hsp_bit-score>
      <Hsp_score>221</Hsp_score>
      <Hsp_evalue>1.43101e-19</Hsp_evalue>
      <Hsp_query-from>136</Hsp_query-from>
      <Hsp_query-to>1071</Hsp_query-to>
      <Hsp_hit-from>167</Hsp_hit-from>
      <Hsp_hit-to>481</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>93</Hsp_identity>
      <Hsp_positive>145</Hsp_positive>
      <Hsp_gaps>91</Hsp_gaps>
      <Hsp_align-len>359</Hsp_align-len>
      <Hsp_qseq>QEPQNFYSVEVGDSTFAVCKRYQNLRPV------------GSGAQGIVA-AYDTIIDRNVAIKKLSRPFQNQTHAKRAFREL--VLMKC----IIKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVI--RMELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVV-------------------KSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVG-----CIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYS--FEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIH</Hsp_qseq>
      <Hsp_hseq>KKPQISATSSQNATTSAAIRKLNKTRPVSFFDKYLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVILYVCLCG--------FP---------PFSDQLGPP------SLKEQI-----LQAKYAFYSPYWDKIDDSVLH----------------LISNLLVLNPDERYNIDEALNHPWFN</Hsp_hseq>
      <Hsp_midline>++PQ   +     +T A  ++    RPV            G+G   +V  A +    + VA+K       +     + FRE   +LM+     I+ LL+ F    S+   Q   ++  + D  L + I  +  L  +    L  Q+L G+K+LH   IIHRD+KP NI++                   + D  +KI DFGLA+             T  Y APEV+   GYT  VD+WS G     C+ G        FP            +QLG P       L+  +      + +Y  YS  ++K+    L                 L+S +LV++P +R  +DEAL HP+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.5077</Hsp_bit-score>
      <Hsp_score>223</Hsp_score>
      <Hsp_evalue>1.63154e-19</Hsp_evalue>
      <Hsp_query-from>334</Hsp_query-from>
      <Hsp_query-to>1083</Hsp_query-to>
      <Hsp_hit-from>163</Hsp_hit-from>
      <Hsp_hit-to>374</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>122</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>255</Hsp_align-len>
      <Hsp_qseq>RELVLMKCIIKLLNVFSPQKSQEDFQDVYLVMDLMDANLC---QVIRMELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVV-KSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMGYTEN-VDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHVWYD</Hsp_qseq>
      <Hsp_hseq>REIVIMK-LISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDN---------------IKKLLLKVQ----------------SGKYQMPSNL-----------SSEARDLISKILVIDPEKRITTQEILKHPLIKKYDD</Hsp_hseq>
      <Hsp_midline>RE+V+MK +I   NV +  +  E+  ++YLV++ +D        V + +L      +   Q++ G+ + HS  I HRDLKP N+++ K +  +KI DFG+A     + ++     + +Y +PE+++G  Y     D+WS G ++  ++   + F   +               + + + ++Q                S +   P  L           +S+ARDL+S++LVIDP KRIT  E L+HP I  + D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>89.7373</Hsp_bit-score>
      <Hsp_score>221</Hsp_score>
      <Hsp_evalue>2.03577e-19</Hsp_evalue>
      <Hsp_query-from>196</Hsp_query-from>
      <Hsp_query-to>765</Hsp_query-to>
      <Hsp_hit-from>619</Hsp_hit-from>
      <Hsp_hit-to>809</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>194</Hsp_align-len>
      <Hsp_qseq>RYQNLRPVGSGAQG-IVAAYDTIIDRNVAIKKLSRPFQNQTHAKRAFRELVLMKCIIKLLNVFSPQKSQEDFQDVYLVMDLMDA-NLCQVI-RMELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGL-ARTAATSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMVR</Hsp_qseq>
      <Hsp_hseq>KYANLVKIGQGASGGVYTAYEIGTNVSVAIKQMN--LEKQPKKELIINEILVMKGS-KHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVTHCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIE</Hsp_hseq>
      <Hsp_midline>+Y NL  +G GA G +  AY+   + +VAIK+++   + Q   +    E+++MK   K  N+ +   S     D++++M+ M+  +L  V+    L   +I  +  + L G++ LHS G++HRD+K  NI++  +  +K+ DFG  A+    +   T  V T Y+ APEV+    Y   VDIWS+G ++ EM+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.8113</Hsp_bit-score>
      <Hsp_score>216</Hsp_score>
      <Hsp_evalue>9.14165e-19</Hsp_evalue>
      <Hsp_query-from>334</Hsp_query-from>
      <Hsp_query-to>1077</Hsp_query-to>
      <Hsp_hit-from>80</Hsp_hit-from>
      <Hsp_hit-to>292</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>57</Hsp_gaps>
      <Hsp_align-len>259</Hsp_align-len>
      <Hsp_qseq>RELVLMKC-----IIKLLNVFSPQKSQEDFQDVYLVMDLMDA----NLCQVIRMEL-DHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMGYTE-NVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHVW</Hsp_qseq>
      <Hsp_hseq>REIIIMKLLNHPNVLRLYDVW------ETNTDLYLVLEYAEKGELFNLL-VERGPLPEHEAIRFF-RQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILF------ALLTGRLPFDEEDGNIRTLLLKVQK---------------------GEFE-------MPSDDEISR----EAQDLIRKILTVDPERRIKTRDILKHPLLQKY</Hsp_hseq>
      <Hsp_midline>RE+++MK      +++L +V+      E   D+YLV++  +     NL  V R  L +HE I +   Q++ G+ + H+ GI+HRDLKP N+++    ++KI DFG+A       ++     + +Y APE++ G+ Y     D+WS G I+        L  GR   D+ +  I  L   V +                       FE        P+D E S+    +A+DL+ ++L +DP +RI   + L+HP +  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.8853</Hsp_bit-score>
      <Hsp_score>211</Hsp_score>
      <Hsp_evalue>3.23871e-18</Hsp_evalue>
      <Hsp_query-from>400</Hsp_query-from>
      <Hsp_query-to>1074</Hsp_query-to>
      <Hsp_hit-from>264</Hsp_hit-from>
      <Hsp_hit-to>468</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>62</Hsp_gaps>
      <Hsp_align-len>246</Hsp_align-len>
      <Hsp_qseq>EDFQDVYLVM------DLMDANLCQVIRMELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSD--CSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMG-------------YTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHV</Hsp_qseq>
      <Hsp_hseq>EDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISR---QILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSG----STQDQLYKQIGR------------------------GSYHEGPLKDFRI----------SEEARDFIDSLLQVDPNNRSTAAKALNHPWIKM</Hsp_hseq>
      <Hsp_midline>ED +  Y+VM      DLMD         E     IS    Q+L  IK++HS GI HRDLKP NI+++ D    +KI DFGLA+       M  +  T  Y APEVI G               Y+  VD+WS+GC++  ++   + F G       +++ +Q+G                         G   E    D             + +ARD +  +L +DP  R T  +AL HP+I +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.5001</Hsp_bit-score>
      <Hsp_score>210</Hsp_score>
      <Hsp_evalue>3.35959e-18</Hsp_evalue>
      <Hsp_query-from>217</Hsp_query-from>
      <Hsp_query-to>828</Hsp_query-to>
      <Hsp_hit-from>220</Hsp_hit-from>
      <Hsp_hit-to>430</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>217</Hsp_align-len>
      <Hsp_qseq>VGSGAQGIVAAYDTIIDRNV-AIKKLSRPFQNQTHAKRAFRELVLMKC-----IIKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVIRMEL-------DHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQL</Hsp_qseq>
      <Hsp_hseq>LGEGAGGSVAKCRLKNGKKVFALKTINTMNTDPEYQKQIFRELQFNKSFKSDYIVQYYGMFTDEQSS----SIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFGVSGEAVNSLAMT-FTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRFPFES-DKITQNVAPIELL</Hsp_hseq>
      <Hsp_midline>+G GA G VA       + V A+K ++    +  + K+ FREL   K      I++   +F+ ++S      +Y+ M+ M     +     L           I  +   +L G+ +LH   +IHRD+KP NI++     +K+ DFG++  A  S  MT +  T +Y APE I G  Y+   D+WS+G  + E+   +  F   D I Q    IE L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.5001</Hsp_bit-score>
      <Hsp_score>210</Hsp_score>
      <Hsp_evalue>3.47081e-18</Hsp_evalue>
      <Hsp_query-from>196</Hsp_query-from>
      <Hsp_query-to>1074</Hsp_query-to>
      <Hsp_hit-from>54</Hsp_hit-from>
      <Hsp_hit-to>308</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>79</Hsp_identity>
      <Hsp_positive>136</Hsp_positive>
      <Hsp_gaps>58</Hsp_gaps>
      <Hsp_align-len>303</Hsp_align-len>
      <Hsp_qseq>RYQNLRPVGSGAQGIVA-AYDTIIDRNVAIKKLSRPFQNQTHAK-RAFRELVLMKC-----IIKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVI--RMELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMGYT-ENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHV</Hsp_qseq>
      <Hsp_hseq>NYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVI---KSKDE---IIMVIEYAGNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPF-------------DDESIPV------LFKNISNGVYTLPKF------------LSPG-----------AAGLIKRMLIVNPLNRISIHEIMQDDWFKV</Hsp_hseq>
      <Hsp_midline> YQ ++ +G G+ G V  AY T   + VA+K +++    ++  + R  RE+  ++      IIKL +V    KS+++   + +V++     L   I  R ++  +       Q++  +++ H   I+HRDLKP N+++    ++KI DFGL+        +     +  Y APEVI G  Y    VD+WS G I+  M+  ++ F             +    PV      L   + N V T P++            L P            A  L+ RML+++PL RI++ E +Q  +  V</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.1073</Hsp_bit-score>
      <Hsp_score>196</Hsp_score>
      <Hsp_evalue>1.44225e-16</Hsp_evalue>
      <Hsp_query-from>196</Hsp_query-from>
      <Hsp_query-to>783</Hsp_query-to>
      <Hsp_hit-from>220</Hsp_hit-from>
      <Hsp_hit-to>421</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>209</Hsp_align-len>
      <Hsp_qseq>RYQNLRPVGSGAQGIVAAYDTIIDRNV-AIKKLSRPFQNQTHAKRAFRELVLMKC-----IIKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVIRMEL-------DHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMVRHKILFP</Hsp_qseq>
      <Hsp_hseq>RIETLGILGEGAGGSVSKCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQFNRSFQSEYIVRYYGMFT----DDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVSGEAVNS-LATTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANGK--FP</Hsp_hseq>
      <Hsp_midline>R + L  +G GA G V+         + A+K ++    +  + K+ FREL   +      I++   +F+     ++   +Y+ M+ M       I   L         + +  +   +L G+ +LH   +IHRD+KP NI++  +  +K+ DFG++  A  S + T +  T +Y APE I G  Y+   D+WS+G  + E+   K  FP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YDL028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:400997:403291:-1 gene:YDL028C transcript:YDL028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MPS1 description:Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]</Hit_def>
  <Hit_accession>YDL028C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.1073</Hsp_bit-score>
      <Hsp_score>196</Hsp_score>
      <Hsp_evalue>2.19498e-16</Hsp_evalue>
      <Hsp_query-from>415</Hsp_query-from>
      <Hsp_query-to>762</Hsp_query-to>
      <Hsp_hit-from>512</Hsp_hit-from>
      <Hsp_hit-to>648</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>138</Hsp_align-len>
      <Hsp_qseq>VYLVMDLMDANLCQVIR----MELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTA---ATSFMMTPYVVTRYYRAPEVILGMGYTEN---------------VDIWSVGCIMGEMV</Hsp_qseq>
      <Hsp_hseq>LYLIMECGDHDLSQILNQRSGMPLDFNFVRFYTKEMLLCIKVVHDAGIVHSDLKPANFVLVKGI-LKIIDFGIANAVPEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMI</Hsp_hseq>
      <Hsp_midline>+YL+M+  D +L Q++     M LD   + +   +ML  IK +H AGI+H DLKP+N V+     LKI+DFG+A        +      + T  Y APE ++ M YT+N                D+WS GCI+ +M+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.337</Hsp_bit-score>
      <Hsp_score>194</Hsp_score>
      <Hsp_evalue>3.60029e-16</Hsp_evalue>
      <Hsp_query-from>409</Hsp_query-from>
      <Hsp_query-to>1068</Hsp_query-to>
      <Hsp_hit-from>415</Hsp_hit-from>
      <Hsp_hit-to>599</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>55</Hsp_gaps>
      <Hsp_align-len>230</Hsp_align-len>
      <Hsp_qseq>QDVYLVMDLMDANLCQVIRMELDHE------RISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMT-PYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITV---DEALQHPYI</Hsp_qseq>
      <Hsp_hseq>EKLYLVLAFINGG---ELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQ---PL----------------------------LFPDGFDPA-----------AKDLLIGLLSRDPSRRLGVNGTDEIRNHPFF</Hsp_hseq>
      <Hsp_midline>+ +YLV+  ++      +   L HE      R  + + ++LC +  LH   +I+RDLKP NI++     + + DFGL +        T  +  T  Y APE++LG GYT+ VD W++G ++ EM+     +   +    + K+++Q   P+                            LFPD   PA           A+DLL  +L  DP +R+ V   DE   HP+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.7221</Hsp_bit-score>
      <Hsp_score>195</Hsp_score>
      <Hsp_evalue>3.7712e-16</Hsp_evalue>
      <Hsp_query-from>457</Hsp_query-from>
      <Hsp_query-to>1074</Hsp_query-to>
      <Hsp_hit-from>1268</Hsp_hit-from>
      <Hsp_hit-to>1442</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>211</Hsp_align-len>
      <Hsp_qseq>VIRM--ELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVV--TRYYRAPEVI-LGMGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHV</Hsp_qseq>
      <Hsp_hseq>LIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPP-----------------------------IPEDTLP-------LISQIGRNFLDACFEINPEKRPTANELLSHPFSEV</Hsp_hseq>
      <Hsp_midline>+IRM    D   I +L  Q+L G+ +LHS GI+HRD+K  N+++  D   KI DFG++R +   +  +   +  T ++ APE++    GY+  VDIWS+GCI+ EM   K  +   + +    K+ +    P                               P+   P       L +   R+ L     I+P KR T +E L HP+  V</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.7962</Hsp_bit-score>
      <Hsp_score>190</Hsp_score>
      <Hsp_evalue>7.94172e-16</Hsp_evalue>
      <Hsp_query-from>208</Hsp_query-from>
      <Hsp_query-to>1092</Hsp_query-to>
      <Hsp_hit-from>194</Hsp_hit-from>
      <Hsp_hit-to>474</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>136</Hsp_positive>
      <Hsp_gaps>58</Hsp_gaps>
      <Hsp_align-len>317</Hsp_align-len>
      <Hsp_qseq>LRPVGSGAQGIVAAYDTIIDRNVAIKKLSRPFQ--NQTHAKRAFRELVLMKCII---KLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVI----------------RMELDHERISYLLYQMLCGIKHLHSA-GIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHVWYDPAE</Hsp_qseq>
      <Hsp_hseq>LGKIGAGNSGTVVKALHVPDSKIVAKK-TIPVEQNNSTIINQLVRELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKLINSIADT-FVGTSTYMSPERIQGNVYSIKGDVWSLGLMIIELVTGE--FPLGGHNDTPDGILDLLQRIVNE----------------------------PSPRLPKDRIYSK----EMTDFVNRCCIKNERERSSIHELLHHDLIMKYVSPSK</Hsp_hseq>
      <Hsp_midline>L  +G+G  G V     + D  +  KK + P +  N T   +  REL ++K +     ++  +    +Q    ++ ++M+  D      I                +   +   IS + Y +L G+ HL+    IIHRD+KPSN+++ S   +K+ DFG+++    S   T +V T  Y +PE I G  Y+   D+WS+G ++ E+V  +  FP   + D  + +++ L   V+E                            P    P D  +SK    +  D ++R  + +  +R ++ E L H  I  +  P++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.0258</Hsp_bit-score>
      <Hsp_score>188</Hsp_score>
      <Hsp_evalue>9.97496e-16</Hsp_evalue>
      <Hsp_query-from>199</Hsp_query-from>
      <Hsp_query-to>762</Hsp_query-to>
      <Hsp_hit-from>70</Hsp_hit-from>
      <Hsp_hit-to>259</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>198</Hsp_align-len>
      <Hsp_qseq>YQNLRPVGSGAQGIVAAYDTIID-RNVAIKKLSR------PFQNQTHAKRAFRELVLMKCIIKLLNVFSPQKSQEDFQDVYLVMDLMDAN-LCQVIR--MELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMV</Hsp_qseq>
      <Hsp_hseq>FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTF------QDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQT--VTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEML</Hsp_hseq>
      <Hsp_midline>+Q +R +G+G+ G V    ++ + R  AIK L +           T+ +R   +LV    +I++   F      +D +++++VMD ++   L  ++R      +    +   +++  +++LH+  II+RDLKP NI++  +  +KI DFG A+   T  +      T  Y APEVI    Y ++VD WS+G ++ EM+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.411</Hsp_bit-score>
      <Hsp_score>189</Hsp_score>
      <Hsp_evalue>2.24963e-15</Hsp_evalue>
      <Hsp_query-from>508</Hsp_query-from>
      <Hsp_query-to>1083</Hsp_query-to>
      <Hsp_hit-from>232</Hsp_hit-from>
      <Hsp_hit-to>382</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>194</Hsp_align-len>
      <Hsp_qseq>MLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMGYT-ENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGY-SFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHVWYD</Hsp_qseq>
      <Hsp_hseq>IASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPF------DDENSSI------LHEKIKK----------GKVDYPSHLSIEVI---------------------SLLTRMIVVDPLRRATLKNVVEHPWMNRGYD</Hsp_hseq>
      <Hsp_midline>+   +++LH+  I+HRDLK  NI++ S   +KI+DFGL+        +  +  + Y+ APE++    YT   VDIWS G ++  +V  K+ F      D  N  I      + E +K+           +  YP + S E +                      LL+RM+V+DPL+R T+   ++HP+++  YD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.2554</Hsp_bit-score>
      <Hsp_score>186</Hsp_score>
      <Hsp_evalue>2.9384e-15</Hsp_evalue>
      <Hsp_query-from>283</Hsp_query-from>
      <Hsp_query-to>855</Hsp_query-to>
      <Hsp_hit-from>194</Hsp_hit-from>
      <Hsp_hit-to>392</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>210</Hsp_align-len>
      <Hsp_qseq>KKLSRPFQNQTHAKRAFRELVLMKCIIKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVIRME---LDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSF-----------MMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTP-----VSEFMK</Hsp_qseq>
      <Hsp_hseq>KRLERTF-----AERSILSEIEHPNIVKLFYSF------HDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIPFYLSEGMK</Hsp_hseq>
      <Hsp_midline>K+L R F     A+R+    +    I+KL   F       D   +YL++  +          E   LD   +S+   ++ C ++ LH+ G+++RDLKP N ++     L + DFGL++ +A               +   + T  Y APE++LG  Y++N D +S+GC++ +M+  K  + G ++    NK+ +    P     +SE MK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.2554</Hsp_bit-score>
      <Hsp_score>186</Hsp_score>
      <Hsp_evalue>3.80175e-15</Hsp_evalue>
      <Hsp_query-from>259</Hsp_query-from>
      <Hsp_query-to>762</Hsp_query-to>
      <Hsp_hit-from>398</Hsp_hit-from>
      <Hsp_hit-to>576</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>191</Hsp_align-len>
      <Hsp_qseq>IIDRNVAIKKLSRPFQNQTHAKRAFRELVLM-----KCIIKLLNVFSPQKSQEDFQDVYLVMDLMDAN-----LCQVIRME-------LDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLA------RTAATSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMV</Hsp_qseq>
      <Hsp_hseq>VVGERVAIKQIR--LSEQPKKQLIMNELLVMNDSRQENIVNFLEAYII-----DDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMVGTP-----YWMAPEIVNQKGYDEKVDVWSLGIMLIEMI</Hsp_hseq>
      <Hsp_midline>++   VAIK++      Q   +    EL++M     + I+  L  +       D ++++++M+ M+       L  V R         L+  +++Y++ +   G+K LH+  IIHRD+K  NI++ S   +KI DFG        R+   + + TP     Y+ APE++   GY E VD+WS+G ++ EM+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.485</Hsp_bit-score>
      <Hsp_score>184</Hsp_score>
      <Hsp_evalue>7.34459e-15</Hsp_evalue>
      <Hsp_query-from>166</Hsp_query-from>
      <Hsp_query-to>792</Hsp_query-to>
      <Hsp_hit-from>88</Hsp_hit-from>
      <Hsp_hit-to>285</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>216</Hsp_align-len>
      <Hsp_qseq>VGDSTFAVCKRYQNLRPVGSGAQGIVAAYDTIIDRNVAIKKLSRPFQNQTHAKRAFRELVLMKCIIKLLNVFSPQKSQEDFQDVYLVMDLM-DANLCQVI--RMELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVV--TRYYRAPEVILGM--GYTENVDIWSVGCIMGEMVRHKILFPGRD</Hsp_qseq>
      <Hsp_hseq>LGEGGFARCFQIKD-------DSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSH----PNIVQFIDCF------EDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANE-SERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARD</Hsp_hseq>
      <Hsp_midline>+G+  FA C + ++         G + A  T+   ++  +K  +   ++    ++         I++ ++ F      ED  +VY+++++  + +L +++  R  L    + +   Q+   IK++HS  +IHRDLK  NI   S+ +LKI DFGLA   A       Y +  T  Y APEV++G   G++  VDIWS+G ++  ++  K  F  RD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.3294</Hsp_bit-score>
      <Hsp_score>181</Hsp_score>
      <Hsp_evalue>1.09025e-14</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>765</Hsp_query-to>
      <Hsp_hit-from>113</Hsp_hit-from>
      <Hsp_hit-to>212</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>100</Hsp_align-len>
      <Hsp_qseq>LDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGM--GYTENVDIWSVGCIMGEMVR</Hsp_qseq>
      <Hsp_hseq>LPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLK</Hsp_hseq>
      <Hsp_midline>L  E++S++++++  G+K+LH    IHRD+K +NI++  +  +K+ DFG++    ++     +V T Y+ APEV+     GY E  DIWS+G    E+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.7146</Hsp_bit-score>
      <Hsp_score>182</Hsp_score>
      <Hsp_evalue>1.22849e-14</Hsp_evalue>
      <Hsp_query-from>412</Hsp_query-from>
      <Hsp_query-to>762</Hsp_query-to>
      <Hsp_hit-from>635</Hsp_hit-from>
      <Hsp_hit-to>762</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>128</Hsp_align-len>
      <Hsp_qseq>DVYLVMDLMDA-NLCQVIRME---------LDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGL-ARTAATSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMV</Hsp_qseq>
      <Hsp_hseq>DLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEML</Hsp_hseq>
      <Hsp_midline>D+++VM+ M+  +L  +I            L   +I+Y++ +   G+K LH   IIHRD+K  N+++ +   +KI DFG  AR           V T Y+ APEV+    Y E +D+WS+G +  EM+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.7146</Hsp_bit-score>
      <Hsp_score>182</Hsp_score>
      <Hsp_evalue>1.23647e-14</Hsp_evalue>
      <Hsp_query-from>412</Hsp_query-from>
      <Hsp_query-to>759</Hsp_query-to>
      <Hsp_hit-from>487</Hsp_hit-from>
      <Hsp_hit-to>605</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>120</Hsp_align-len>
      <Hsp_qseq>DVYLVMDLMDAN-LCQVIRME--LDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCIMGEM</Hsp_qseq>
      <Hsp_hseq>DLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNT-FCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEM</Hsp_hseq>
      <Hsp_midline>D+YLV D M    L   ++ E     +R  + + +++  ++HLH   I++RDLKP NI++ ++ ++ + DFGL++        T +  T  Y APE++L   GYT+ VD WS+G ++ EM</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.3294</Hsp_bit-score>
      <Hsp_score>181</Hsp_score>
      <Hsp_evalue>1.44468e-14</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>1068</Hsp_query-to>
      <Hsp_hit-from>442</Hsp_hit-from>
      <Hsp_hit-to>602</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>203</Hsp_align-len>
      <Hsp_qseq>LDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMT-PYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRI---TVDEALQHPYI</Hsp_qseq>
      <Hsp_hseq>FDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQ-------------EPLV------------------FPDG-FDRD----------AKDLLIGLLSRDPTRRLGYNGADEIRNHPFF</Hsp_hseq>
      <Hsp_midline> D  R  +   ++LC + +LH   +++RDLKP NI++     + + DFGL +        T  +  T  Y APE++LG+GYT+ VD W++G ++ EM+     +   D    + K+++             +P V                  FPD  F  D          A+DLL  +L  DP +R+     DE   HP+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.9442</Hsp_bit-score>
      <Hsp_score>180</Hsp_score>
      <Hsp_evalue>2.74942e-14</Hsp_evalue>
      <Hsp_query-from>208</Hsp_query-from>
      <Hsp_query-to>819</Hsp_query-to>
      <Hsp_hit-from>827</Hsp_hit-from>
      <Hsp_hit-to>1037</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>219</Hsp_align-len>
      <Hsp_qseq>LRPVGSGAQG-IVAAYDTIIDRNVAIKKLSRPFQNQTH---AKRAFRELVLMKCIIK---LLNVFSPQKSQEDFQDVYLVMDLMDAN--LCQVIRMELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLAR------TAATSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVI</Hsp_qseq>
      <Hsp_hseq>LKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTE---NRIYFAMEFIGGGDLMWHVQNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTP-----EFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAIL</Hsp_hseq>
      <Hsp_midline>L+ +G G  G ++ +     DR  AIK L +    Q H   + RA +++ L+    K   L N++   +++     +Y  M+ +     +  V    L   R  +   ++L  +K+ H  G+I+RDLK  NI++  +  +KI D+GL +         ++F  TP      + APE++    YT+ VD W+ G ++ +M+  +  F G D  + +N ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.4034</Hsp_bit-score>
      <Hsp_score>176</Hsp_score>
      <Hsp_evalue>2.9459e-14</Hsp_evalue>
      <Hsp_query-from>199</Hsp_query-from>
      <Hsp_query-to>819</Hsp_query-to>
      <Hsp_hit-from>87</Hsp_hit-from>
      <Hsp_hit-to>295</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>220</Hsp_align-len>
      <Hsp_qseq>YQNLRPVGSGAQGIVAAYDTIID-RNVAIKKLSRPFQ------NQTHAKRAFRELVLMKCIIKLLNVFSPQKSQEDFQDVYLVMDLMDAN-LCQVIR--MELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLAR---TAATSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVI</Hsp_qseq>
      <Hsp_hseq>FQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTF------QDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTP-----DYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKIL</Hsp_hseq>
      <Hsp_midline>+Q LR +G+G+ G V    +  + R  A+K L +           T+ +R    +V    II++   F      +D Q ++++MD ++   L  ++R      +    +   ++   +++LHS  II+RDLKP NI++  +  +KI DFG A+       +   TP      Y APEV+    Y +++D WS G ++ EM+     F   + +  + K++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YDL214C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:74446:76545:-1 gene:YDL214C transcript:YDL214C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR2 description:Serine/threonine protein kinase; inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance; PRR2 has a paralog, NPR1, that arose from the whole genome duplication [Source:SGD;Acc:S000002373]</Hit_def>
  <Hit_accession>YDL214C</Hit_accession>
  <Hit_len>699</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>3.92532e-14</Hsp_evalue>
      <Hsp_query-from>145</Hsp_query-from>
      <Hsp_query-to>1131</Hsp_query-to>
      <Hsp_hit-from>343</Hsp_hit-from>
      <Hsp_hit-to>674</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>83</Hsp_identity>
      <Hsp_positive>145</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>340</Hsp_align-len>
      <Hsp_qseq>QNFYSVEVGDSTFAVCKRYQNLRPV-GSGAQGIVAAYDTIIDRNVAIKKLSRPFQNQTHAKRAFRELVLMKCIIKLL---NVFSPQKSQEDFQDVYLVMDLMDANLCQVIRME-LDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLART-----AATSFMMTPYVVTRYYRAPEVILGMGYT-ENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHVWYDPAEVNGPSPQISDRRL</Hsp_qseq>
      <Hsp_hseq>QALYS-NIEASTDLVSRKYRDLDVVLGEGSGGKVKLVQRVLDNKVFALKEYRSKKKRESERKYIKNIISEYCIASTLKNPNICETLEILYEKGKIFQILEYCEYDLFSLVMSEKMHYEEICCLFKQLINGVKYLHDIGLSHRDLKLDNCVVTRRGILKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFYFNEYDPRALDVWSVGIIFFCMITRRFPWKYPKVKDVQFKAFCS-GRGVSSFKDLV---TRPATDDSNNYDNDGYEEGVID-MGPNFILHR--LPEETHKIMRRILEVSPFRRITINGILQDGWIKEIETCQVVGAASPNEASLRI</Hsp_hseq>
      <Hsp_midline>Q  YS  +  ST  V ++Y++L  V G G+ G V     ++D  V   K  R  + +   ++  + ++   CI   L   N+    +   +   ++ +++  + +L  ++  E + +E I  L  Q++ G+K+LH  G+ HRDLK  N VV     LK++DFG +       ++        V +  Y +PEV     Y    +D+WSVG I   M+  +  +      D   K     G  VS F   +    R   +    Y    +E+   D + P    H      +   ++ R+L + P +RIT++  LQ  +I        V   SP  +  R+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>4.76484e-14</Hsp_evalue>
      <Hsp_query-from>199</Hsp_query-from>
      <Hsp_query-to>762</Hsp_query-to>
      <Hsp_hit-from>88</Hsp_hit-from>
      <Hsp_hit-to>277</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>198</Hsp_align-len>
      <Hsp_qseq>YQNLRPVGSGAQGIVAAYDTIID-RNVAIKKLSRPF------QNQTHAKRAFRELVLMKCIIKLLNVFSPQKSQEDFQDVYLVMDLMDAN-LCQVIR--MELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMV</Hsp_qseq>
      <Hsp_hseq>FQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTF------QDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPD--VTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEML</Hsp_hseq>
      <Hsp_midline>+Q LR +G+G+ G V    +  + R  A+K L +           T+ +R    +V    II++   F      +D Q V++VMD ++   L  ++R      +    +   ++   +++LHS  II+RDLKP NI++  +  +KI DFG A+      +      T  Y APEV+    Y ++VD WS G ++ EM+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.7886</Hsp_bit-score>
      <Hsp_score>177</Hsp_score>
      <Hsp_evalue>5.39137e-14</Hsp_evalue>
      <Hsp_query-from>217</Hsp_query-from>
      <Hsp_query-to>1095</Hsp_query-to>
      <Hsp_hit-from>131</Hsp_hit-from>
      <Hsp_hit-to>409</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>81</Hsp_identity>
      <Hsp_positive>137</Hsp_positive>
      <Hsp_gaps>84</Hsp_gaps>
      <Hsp_align-len>328</Hsp_align-len>
      <Hsp_qseq>VGSGA-QGIVAAYDTIIDRNVAIKKLSRPF-------QNQTHAKRAFRELVLMKCIIKLLNVFSPQKSQEDFQDVYLVMDLM-DANLCQVIRM--ELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLART----AATSFMMTPY----------VVTRYYRAPEVILGMGYTEN-VDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIH--------VWYD-PAEV</Hsp_qseq>
      <Hsp_hseq>LGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQKLNGTKGIFKLFFTF------QDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPE-LLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVM------------KIQ---------------YAFTAGFPQIV---------------KDLVKKLLVRDPNDRLTIKQIKAHLFFHEVNFEDGSVWDDNPPEI</Hsp_hseq>
      <Hsp_midline>+G G+   +V A      +  A+K LS+ +       +  T  K A ++L   K I KL   F      +D   +Y +++     +   +I+    L+     Y   Q++  +  LH+ GIIHRD+KP NI++  +  +K+ DFG A+      + +    PY          V T  Y +PE +L   YT++  DIW+ GCI+ +M+  K  F   +    + KV+            ++Q               Y+F   FP  +               +DL+ ++LV DP  R+T+ +   H + H        VW D P E+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.7886</Hsp_bit-score>
      <Hsp_score>177</Hsp_score>
      <Hsp_evalue>5.54692e-14</Hsp_evalue>
      <Hsp_query-from>322</Hsp_query-from>
      <Hsp_query-to>1131</Hsp_query-to>
      <Hsp_hit-from>228</Hsp_hit-from>
      <Hsp_hit-to>482</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>129</Hsp_positive>
      <Hsp_gaps>83</Hsp_gaps>
      <Hsp_align-len>304</Hsp_align-len>
      <Hsp_qseq>KRAFRELVLMKCIIKLLNVFSPQKSQEDFQDVYLVMDLM-DANLCQVIRM--ELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLAR--TAATSFMMTP----------YVVTRYYRAPEVILGMGYTE-NVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIH--------VW------YDPAEVNGPS----PQISDRRL</Hsp_qseq>
      <Hsp_hseq>KTALQKLNNSPSVVRLFSTF------QDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPE-LLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVM------------KVQ---------------YAFTPGFPLII---------------RDLVKKILVKNLDRRLTISQIKEHHFFKDLNFKDGSVWSKTPPEIKPYKINAKSMQAMPSGSDRKL</Hsp_hseq>
      <Hsp_midline>K A ++L     +++L + F      +D   +Y +++   + +   +++    LD     Y   Q++  I +LHS GIIHRD+KP NI++  +  +K+ DFG A+      + +  P          +V T  Y +PE +L   +T+   DIW+ GCI+ +M+  K  F   +    + KV+            ++Q               Y+F   FP  +               RDL+ ++LV +  +R+T+ +  +H +          VW        P ++N  S    P  SDR+L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.7886</Hsp_bit-score>
      <Hsp_score>177</Hsp_score>
      <Hsp_evalue>5.59365e-14</Hsp_evalue>
      <Hsp_query-from>133</Hsp_query-from>
      <Hsp_query-to>762</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>214</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>215</Hsp_align-len>
      <Hsp_qseq>VQEPQNFYSVEVGDSTFAVCKRYQNLRPVGSGAQGIV-AAYDTIIDRNVAIKKLSRPFQNQTHAKRAFRELVLMKCIIKLLNVFSPQKSQEDFQDVYLVMD-LMDANLCQVIR-MELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGL-ARTAATSFMMTPYVVTRYYRAPEVIL-GMGYTENVDIWSVGCIMGEMV</Hsp_qseq>
      <Hsp_hseq>TTKPQNSKQ-GLAEGEMDVSSLFKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNL-DSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLRPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIA</Hsp_hseq>
      <Hsp_midline>  +PQN     + +    V   ++    +G G  G+V   Y+    R  AIK L+    +    +   RE+  +  + ++ N+     S      ++++M+     +L  ++R  ++D + I  ++ ++L  +K +H   +IHRD+K +N+++ ++ ++K+ DFG+ A+   TS        T Y+ APEVI+ G+ Y   VDIWS+G    E+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>6.04225e-14</Hsp_evalue>
      <Hsp_query-from>187</Hsp_query-from>
      <Hsp_query-to>825</Hsp_query-to>
      <Hsp_hit-from>46</Hsp_hit-from>
      <Hsp_hit-to>291</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>119</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>250</Hsp_align-len>
      <Hsp_qseq>VCKRYQNLRPVGSGAQGIVA-AYDTIIDRNVAIKKLSR-------PFQNQTHAKRAFRELVLMK-C----IIKLLNVFSPQKSQEDFQDVYLVMDLMD---ANLCQVIRMELDHERISYLLYQ--------MLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATS----------FMMTPYVVTRYYRAPEVILG---MGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQ</Hsp_qseq>
      <Hsp_hseq>ILNNFEILATLGNGQYGKVKLARDLGTGALVAIKILNRFEKRSGYSLQLKVENPRVNQEIEVMKRCHHENVVELYEILNDPESTK----VYLVLEYCSRGPVKWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPFNANSGLELFDSIINK</Hsp_hseq>
      <Hsp_midline>+   ++ L  +G+G  G V  A D      VAIK L+R         Q +    R  +E+ +MK C    +++L  + +  +S +    VYLV++         C   +ME+     S L +Q        ++ G+++LHS GI HRD+KPSN+++ S+ ++KI DFG+A + AT            + +  + T  + APE+         +  +DIWS+G  +  ++  K+ F     ++ ++ +I +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.7886</Hsp_bit-score>
      <Hsp_score>177</Hsp_score>
      <Hsp_evalue>6.76732e-14</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>762</Hsp_query-to>
      <Hsp_hit-from>805</Hsp_hit-from>
      <Hsp_hit-to>919</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>115</Hsp_align-len>
      <Hsp_qseq>LDHERISY--LLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTA---------------ATSFMMTPYVVTRYYRAPEVILGMG-YTENVDIWSVGCIMGEMV</Hsp_qseq>
      <Hsp_hseq>LNQQRDEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNVKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVLDGTGHYNEKIDMYSLGIIFFEMI</Hsp_hseq>
      <Hsp_midline>L+ +R  Y  L  Q+L  + ++HS GIIHRDLKP NI +    ++KI DFGLA+                  +S  +T  + T  Y A EV+ G G Y E +D++S+G I  EM+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.4034</Hsp_bit-score>
      <Hsp_score>176</Hsp_score>
      <Hsp_evalue>7.30615e-14</Hsp_evalue>
      <Hsp_query-from>196</Hsp_query-from>
      <Hsp_query-to>1092</Hsp_query-to>
      <Hsp_hit-from>24</Hsp_hit-from>
      <Hsp_hit-to>276</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>129</Hsp_positive>
      <Hsp_gaps>56</Hsp_gaps>
      <Hsp_align-len>304</Hsp_align-len>
      <Hsp_qseq>RYQNLRPVGSGAQGIV-AAYDTIIDRNVAIKKLSRPFQNQTHAKRAFRELVLMKCIIKLLNVFSPQKSQEDFQDVYLVMD-LMDANLCQVIRME---LDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHVWYDPAE</Hsp_qseq>
      <Hsp_hseq>QYHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVV--YENDEELNDIMAEISLLKNL-NHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSALT--LAGTLNWMAPEILGNRGASTLSDIWSLGATVVEML-----------------------TKNPPYHNLTDANIYYAVENDTYYPPSSF-------------------SEPLKDFLSKCFVKNMYKRPTADQLLK----HVWINSTE</Hsp_hseq>
      <Hsp_midline>+Y   + +G G+ G+V  A +   D+ VAIK++   ++N         E+ L+K +    N+           ++Y++++   + +L ++I      L        + Q L G+K+LH  G+IHRD+K +NI++ +D ++K+ DFG++    +S +      T  + APE++   G +   DIWS+G  + EM+                       T    +       +   VE    YP  SF                   +   +D LS+  V +  KR T D+ L+    HVW +  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>9.34515e-14</Hsp_evalue>
      <Hsp_query-from>496</Hsp_query-from>
      <Hsp_query-to>1068</Hsp_query-to>
      <Hsp_hit-from>155</Hsp_hit-from>
      <Hsp_hit-to>313</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>194</Hsp_align-len>
      <Hsp_qseq>LLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLART-AATSFMMTPYVVTRYYRAPEVILGMGYTE--NVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYI</Hsp_qseq>
      <Hsp_hseq>LFSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVNEFCSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVIL-----YAILAGYLPWDDDPN-------NPEGSDIGRLY----NYINSTPLK--------FPDYILPI-----------PRDLLRRMLVSDPKKRINLKQIKKHEWL</Hsp_hseq>
      <Hsp_midline>L  Q++ G+ ++HS G++HRDLK  N+++  + +L I DFG      + + +M     +  Y APE+++     E    DIWS G I+     + IL     + D  N        P    + RL     NY+ + P          FPD + P             RDLL RMLV DP KRI + +  +H ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>1.691e-13</Hsp_evalue>
      <Hsp_query-from>496</Hsp_query-from>
      <Hsp_query-to>1077</Hsp_query-to>
      <Hsp_hit-from>137</Hsp_hit-from>
      <Hsp_hit-to>290</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>196</Hsp_align-len>
      <Hsp_qseq>LLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMGYTE-NVDIWSVGCIMGEMVRHKILFPGRDYID-QWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHVW</Hsp_qseq>
      <Hsp_hseq>LFAQISGAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTRECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEE-----------------------PKYDA----KVIPD---------------DARDLISRLLAKNPGERPSLSQVLRHPFLQPY</Hsp_hseq>
      <Hsp_midline>L  Q+   + + HS   +HRDLK  NI++  + + K+ DFG  R   T   +     T  Y APE+I    Y    +DIWS+G I+  ++   + F   D    +W  V E+                       P+Y      K+ PD                ARDL+SR+L  +P +R ++ + L+HP++  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YLL019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:105686:107899:-1 gene:YLL019C transcript:YLL019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KNS1 description:Protein kinase involved in negative regulation of PolIII transcription; effector kinase of the TOR signaling pathway and phosphorylates Rpc53p to regulate ribosome and tRNA biosynthesis; member of the LAMMER family of protein kinases, which are serine/threonine kinases also capable of phosphorylating tyrosine residues; capable of autophosphorylation [Source:SGD;Acc:S000003942]</Hit_def>
  <Hit_accession>YLL019C</Hit_accession>
  <Hit_len>737</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.8626</Hsp_bit-score>
      <Hsp_score>172</Hsp_score>
      <Hsp_evalue>1.85543e-13</Hsp_evalue>
      <Hsp_query-from>487</Hsp_query-from>
      <Hsp_query-to>837</Hsp_query-to>
      <Hsp_hit-from>417</Hsp_hit-from>
      <Hsp_hit-to>563</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>150</Hsp_align-len>
      <Hsp_qseq>ISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDC--------------------------------SLKILDFGLARTAATSFMMTPYVV-TRYYRAPEVILGMGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTP</Hsp_qseq>
      <Hsp_hseq>IQAIARQLIRSVCFLHDLGIIHTDLKPENILICDETHIAQKLPLKTVQSLSKRRREASKGKRKILKNPEIKIIDFG---SAIFHYEYHPPVISTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVIGESLYPIHENLEHMAMMQRINGTP</Hsp_hseq>
      <Hsp_midline>I  +  Q++  +  LH  GIIH DLKP NI++  +                                  +KI+DFG   +A   +   P V+ TR+YRAPE++LG+G++   DIWS+ C++ E+V  + L+P  + ++    +    GTP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.3218</Hsp_bit-score>
      <Hsp_score>168</Hsp_score>
      <Hsp_evalue>4.3324e-13</Hsp_evalue>
      <Hsp_query-from>121</Hsp_query-from>
      <Hsp_query-to>1068</Hsp_query-to>
      <Hsp_hit-from>11</Hsp_hit-from>
      <Hsp_hit-to>299</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>84</Hsp_identity>
      <Hsp_positive>150</Hsp_positive>
      <Hsp_gaps>69</Hsp_gaps>
      <Hsp_align-len>337</Hsp_align-len>
      <Hsp_qseq>SGRPVQEPQNFYSVEVGDSTFAVCKRYQNLRPVGSGAQGIV-AAYDTIIDRNVAIKKLSRPF--QNQTHAKRAFRELVLMK-----CIIKLLNVFSPQKSQEDFQDVYLVM------DLMDANLCQVIRMELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNI--VVKSDCS-LKILDFGLA-RTAATSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMVRHKILFPG---RDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYI</Hsp_qseq>
      <Hsp_hseq>SPKQTEEDSEGKMAHVQPASYVNKKKYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWF---ESKDKF---YIITQLAKGGELFDRILKKGKFTEEDAVRI---LVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDEC---------------------------TTGEYP-VKFHRPYWDSV-----------SNKAKQFILKALNLDPSKRPTAAELLEDPWI</Hsp_hseq>
      <Hsp_midline>S +  +E        V  +++   K+Y   + +G+G  G+V  A +T    +VA+K L +     N+   +  + EL +++      I+   + F   +S++ F   Y++       +L D  L +    E D  RI   L ++L  +K++HS  I+HRDLKP N+  + KSD S L + DFG+A R  +   ++     +  Y APEV+   G+ +  DIWS+G I   ++     F     +D++D+                            T   YP   F + + D++           +++A+  + + L +DP KR T  E L+ P+I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.3218</Hsp_bit-score>
      <Hsp_score>168</Hsp_score>
      <Hsp_evalue>5.8237e-13</Hsp_evalue>
      <Hsp_query-from>403</Hsp_query-from>
      <Hsp_query-to>1128</Hsp_query-to>
      <Hsp_hit-from>255</Hsp_hit-from>
      <Hsp_hit-to>501</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>125</Hsp_positive>
      <Hsp_gaps>85</Hsp_gaps>
      <Hsp_align-len>287</Hsp_align-len>
      <Hsp_qseq>DFQDV----YLVMDLMDAN--LCQVIRMELDHERIS-YLLYQMLCGIKHLHSAGIIHRDLKPSNIV---------------------VKSDCSL-------------KILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHVWYDPAEVNGPSPQ----ISDRR</Hsp_qseq>
      <Hsp_hseq>DFQETDSYYYIIQELLTGGEIFGEIVRLTYFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKNTKTP-CGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTML---CGFPPF-----YDEKIDTLTEKISR-------------------GEYTFLKPWWDEI-----------SAGAKNAVAKLLELEPSKRYDIDQFLDDPWLNT-FDCLPKEGESSQKKAGTSERR</Hsp_hseq>
      <Hsp_midline>DFQ+     Y++ +L+       +++R+    E +S +++ Q+   +KH+HS G++HRD+KP N++                      K+D  +             K+ DFGL++   +    TP   T  Y APEV+    Y+  VD+W +GC++  M+     FP       +++ I+ L   +S                      Y+F K + D +           ++ A++ ++++L ++P KR  +D+ L  P+++  +D     G S Q     S+RR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>1.18201e-12</Hsp_evalue>
      <Hsp_query-from>487</Hsp_query-from>
      <Hsp_query-to>1068</Hsp_query-to>
      <Hsp_hit-from>556</Hsp_hit-from>
      <Hsp_hit-to>712</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>198</Hsp_align-len>
      <Hsp_qseq>ISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAA----TSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYI</Hsp_qseq>
      <Hsp_hseq>ITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPFPD---------------------FSQMQAIFKIGTNTTPEIPSWA--------------------TSEGKNFLRKAFELDYQYRPSALELLQHPWL</Hsp_hseq>
      <Hsp_midline>I+    Q+L G+ +LH   IIHRD+K +NI++     +KI DFG+++  +              + ++ +PEV+     T   DIWS GC++ EM   K  FP                        ++Q   +    T P  P ++                     S+ ++ L +   +D   R +  E LQHP++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.5514</Hsp_bit-score>
      <Hsp_score>166</Hsp_score>
      <Hsp_evalue>1.26851e-12</Hsp_evalue>
      <Hsp_query-from>496</Hsp_query-from>
      <Hsp_query-to>762</Hsp_query-to>
      <Hsp_hit-from>1210</Hsp_hit-from>
      <Hsp_hit-to>1298</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>90</Hsp_align-len>
      <Hsp_qseq>LLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMGYT-ENVDIWSVGCIMGEMV</Hsp_qseq>
      <Hsp_hseq>IFKQVVAGIKHLHDQGIVHRDIKDENVIVDSKGFVKIIDFGSA-AYVKSGPFDVFVGTIDYAAPEVLGGNPYEGQPQDIWAIGILLYTVV</Hsp_hseq>
      <Hsp_midline>+  Q++ GIKHLH  GI+HRD+K  N++V S   +KI+DFG A     S     +V T  Y APEV+ G  Y  +  DIW++G ++  +V</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YMR216C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:698811:701039:-1 gene:YMR216C transcript:YMR216C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKY1 description:SR protein kinase (SRPK); involved in regulating proteins involved in mRNA metabolism and cation homeostasis; similar to human SRPK1 [Source:SGD;Acc:S000004829]</Hit_def>
  <Hit_accession>YMR216C</Hit_accession>
  <Hit_len>742</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>1.3141e-12</Hsp_evalue>
      <Hsp_query-from>565</Hsp_query-from>
      <Hsp_query-to>1068</Hsp_query-to>
      <Hsp_hit-from>540</Hsp_hit-from>
      <Hsp_hit-to>706</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>175</Hsp_align-len>
      <Hsp_qseq>PSNIVVKSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMVRHKILF---PGRDYI---DQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFP-DALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYI</Hsp_qseq>
      <Hsp_hseq>PENLI-----QIKIADLGNACWYDEHY--TNSIQTREYRSPEVLLGAPWGCGADIWSTACLIFELITGDFLFEPDEGHSYTKDDDHIAQIIELLGE-LPSYLLRNGKYTRTFFNSRGLLRNISKLKFWPLEDVLTEKYKFSKDEAKEISDFLSPMLQLDPRKRADAGGLVNHPWL</Hsp_hseq>
      <Hsp_midline>P N++      +KI D G A      +  T  + TR YR+PEV+LG  +    DIWS  C++ E++    LF    G  Y    D   ++IE LG  +  ++ R     R +  +R      S  K +P + +     + SK +A +  D LS ML +DP KR      + HP++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YHR079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:258244:261591:-1 gene:YHR079C transcript:YHR079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IRE1 description:Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; role in homeostatic adaptation to ER stress; Kar2p binds inactive Ire1p and releases from it upon ER stress [Source:SGD;Acc:S000001121]</Hit_def>
  <Hit_accession>YHR079C</Hit_accession>
  <Hit_len>1115</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>1.45689e-12</Hsp_evalue>
      <Hsp_query-from>217</Hsp_query-from>
      <Hsp_query-to>1062</Hsp_query-to>
      <Hsp_hit-from>680</Hsp_hit-from>
      <Hsp_hit-to>978</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>84</Hsp_identity>
      <Hsp_positive>142</Hsp_positive>
      <Hsp_gaps>51</Hsp_gaps>
      <Hsp_align-len>316</Hsp_align-len>
      <Hsp_qseq>VGSGAQGIVAAYDTIIDRNVAIKKLSRPFQNQTHAKRAFRELVLMKCIIKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVI----------RMELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDC-----------SLKIL--DFGLAR---TAATSFM--MTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYP---GYSFEKLFPDALFPADSE---HSKLKASQARDLLSRMLVIDPLKRITVDEALQHP</Hsp_qseq>
      <Hsp_hseq>LGYGSSGTVVFQGSFQGRPVAVKRMLIDF-----CDIALMEIKLLTESDDHPNVIRYYCSETTDRFLYIALELCNLNLQDLVESKNVSDENLKLQKEYNPIS-LLRQIASGVAHLHSLKIIHRDLKPQNILVSTSSRFTADQQTGAENLRILISDFGLCKKLDSGQSSFRTNLNNPSGTSGWRAPELL-----EESNNLQCQVETEHSSSRHTVV-SSDSFYDPFTK--RRLTRSIDIFS---MGCVFYYILSKGKHPFGDKYSRESNIIRGIFSLDEMKCLHDRSLIAEATDLISQMIDHDPLKRPTAMKVLRHP</Hsp_hseq>
      <Hsp_midline>+G G+ G V    +   R VA+K++   F        A  E+ L+       NV     S+   + +Y+ ++L + NL  ++          +++ ++  IS LL Q+  G+ HLHS  IIHRDLKP NI+V +             +L+IL  DFGL +   +  +SF   +     T  +RAPE++      E+ ++           RH ++     + D + K   +L   +  F       V  Y+ ++ ++P    YS E      +F  D     H +   ++A DL+S+M+  DPLKR T  + L+HP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>1.9623e-12</Hsp_evalue>
      <Hsp_query-from>526</Hsp_query-from>
      <Hsp_query-to>1131</Hsp_query-to>
      <Hsp_hit-from>259</Hsp_hit-from>
      <Hsp_hit-to>414</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>204</Hsp_align-len>
      <Hsp_qseq>HLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMGYT-ENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGY-SFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHVWYDPAEVNGPSPQISDRRL</Hsp_qseq>
      <Hsp_hseq>YLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPF------DDENSSV------LHEKIK----------QGKVEYPQHLSIEVI---------------------SLLSKMLVVDPKRRATLKQVVEHHWMVRGF-----NGPPPSYLPKRV</Hsp_hseq>
      <Hsp_midline>+LH+  I+HRDLK  NI++     +KI+DFGL+    +   +  +  + Y+ APE++    YT   VD+WS G ++  +V  K+ F      D  N  +      + E +K          + +  YP + S E +                      LLS+MLV+DP +R T+ + ++H ++   +     NGP P    +R+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>1.96295e-12</Hsp_evalue>
      <Hsp_query-from>358</Hsp_query-from>
      <Hsp_query-to>1095</Hsp_query-to>
      <Hsp_hit-from>75</Hsp_hit-from>
      <Hsp_hit-to>304</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>62</Hsp_gaps>
      <Hsp_align-len>269</Hsp_align-len>
      <Hsp_qseq>IIKLLNVFSPQKSQEDFQDVYLVMDLMDAN--LCQVIRM-ELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFM------------------MTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHV--WYDPAEV</Hsp_qseq>
      <Hsp_hseq>IIKLYYTF------HDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPFRGENELKTFEKIVA-LDYPWG-------PNNRINNSTSPINP-------------------------LVINLVQKILVIEVNERISLEQIKRHPYFSKVDWNDKIKI</Hsp_hseq>
      <Hsp_midline>IIKL   F       D +++Y V+D       L  + +M   +     +   Q++  ++ +HS GIIHRDLKP N+++  D  L I DFG A T   S                       +V T  Y +PE++L        DIW++GC++ + V+ +  F G + +  + K++  L  P         P  R    T P  P                            +L+ ++LVI+  +RI++++  +HPY     W D  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YOR267C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:822588:824867:-1 gene:YOR267C transcript:YOR267C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRK1 description:Protein kinase; implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005793]</Hit_def>
  <Hit_accession>YOR267C</Hit_accession>
  <Hit_len>759</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>2.42522e-12</Hsp_evalue>
      <Hsp_query-from>217</Hsp_query-from>
      <Hsp_query-to>762</Hsp_query-to>
      <Hsp_hit-from>221</Hsp_hit-from>
      <Hsp_hit-to>415</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>199</Hsp_align-len>
      <Hsp_qseq>VGSGAQGIVAAYDTIIDRNVAIKKLSRPFQNQTHAKRAFRELVLMKCI---------IKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVIRM-ELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSF-----MMTPYVVTRYYRAPEVILGMGY--TENVDIWSVGCIMGEMV</Hsp_qseq>
      <Hsp_hseq>LGSGAGGSVKVLVRPTDGATFAVKEFRPRKPNESVKEYAKKCTAEFCIGSTLHHPNVIETVDVFSDSKQNK----YYEVMEYCPIDFFAVVMTGKMSRGEINCCLKQLTEGVKYLHSMGLAHRDLKLDNCVMTSQGILKLIDFGSAVVFRYPFEDGVTMAHGIVGSDPYLAPEVITSTKSYDPQCVDIWSIGIIYCCMV</Hsp_hseq>
      <Hsp_midline>+GSGA G V       D      K  RP +     K   ++     CI         I+ ++VFS  K  +     Y VM+    +   V+   ++    I+  L Q+  G+K+LHS G+ HRDLK  N V+ S   LK++DFG A      F     M    V +  Y APEVI        + VDIWS+G I   MV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>3.04778e-12</Hsp_evalue>
      <Hsp_query-from>403</Hsp_query-from>
      <Hsp_query-to>780</Hsp_query-to>
      <Hsp_hit-from>152</Hsp_hit-from>
      <Hsp_hit-to>289</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>140</Hsp_align-len>
      <Hsp_qseq>DFQDVYLVMDLMDA-NLCQVIRMEL---DHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS-DCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVI-LGMGYTE--------NVDIWSVGCIMGEMVRHKILF</Hsp_qseq>
      <Hsp_hseq>DFFDSYIIMEYCSGGDLYEAIKADAVPKKTKSITHIITQIMDAIEYVHNKGIYHRDIKPENILISGIDWTIKLTDWGLATTDKTS--MDRNVGSERYMSPELFDSNLDIKERKEPYDCAKVDLWAMGIVFLNIVFHKNPF</Hsp_hseq>
      <Hsp_midline>DF D Y++M+     +L + I+ +      + I++++ Q++  I+++H+ GI HRD+KP NI++   D ++K+ D+GLA T  TS  M   V +  Y +PE+    +   E         VD+W++G +   +V HK  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>5.11198e-12</Hsp_evalue>
      <Hsp_query-from>175</Hsp_query-from>
      <Hsp_query-to>750</Hsp_query-to>
      <Hsp_hit-from>125</Hsp_hit-from>
      <Hsp_hit-to>369</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>61</Hsp_gaps>
      <Hsp_align-len>249</Hsp_align-len>
      <Hsp_qseq>STFAVCKRYQNLRPVGSGAQGIVA-AYDTIIDRNVAIKKLSRPFQNQ------------THAKRAFRELVLMK-C----IIKLLNVFSPQKSQEDFQDVYLVMDLM---DANLCQVIRMELDHERISYLLYQ--------MLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTA-----------ATSFMMTPYVVTRYYRAPEVILGM-GYT------EN----------VDIWSVGCIM</Hsp_qseq>
      <Hsp_hseq>SKRKVLNTYEIIKELGHGQHGKVKLARDILSKQLVAIKIVDRHEKKQRKFFTFIKSSKISENDKIKREIAIMKKCHHKHVVQLIEVLDDLKSRK----IYLVLEYCSRGEVKWCPPDCMESDAKGPSLLSFQETREILRGVVLGLEYLHYQGIIHRDIKPANLLISGDGTVKISDFGVSLAASSTNSSDSSESLDELELAKTVGTPAFFAPEMCLGEDAFTRYNLTKENLFRGSCISFMIDIWAVGVTL</Hsp_hseq>
      <Hsp_midline>S   V   Y+ ++ +G G  G V  A D +  + VAIK + R  + Q            +   +  RE+ +MK C    +++L+ V    KS++    +YLV++     +   C    ME D +  S L +Q        ++ G+++LH  GIIHRD+KP+N+++  D ++KI DFG++  A                +   V T  + APE+ LG   +T      EN          +DIW+VG  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YNL183C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:293137:295509:-1 gene:YNL183C transcript:YNL183C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NPR1 description:Protein kinase; stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p; negatively regulates Ldb19p-mediated endocytosis through phosphorylation of Ldb19p, which prevents its association with the plasma membrane; Npr1p activity is negatively regulated via phosphorylation by the TOR complex; NPR1 has a paralog, PRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005127]</Hit_def>
  <Hit_accession>YNL183C</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>6.60874e-12</Hsp_evalue>
      <Hsp_query-from>277</Hsp_query-from>
      <Hsp_query-to>1068</Hsp_query-to>
      <Hsp_hit-from>465</Hsp_hit-from>
      <Hsp_hit-to>742</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>129</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>295</Hsp_align-len>
      <Hsp_qseq>AIKKLSRPFQNQTHAKRAF-RELVLMKCIIKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQ------VIRMELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFM-----MTPYVVTRYYRAPEVILGMGYTEN-VDIWSVGCIMGEMV--------------RHKILFPGRDYIDQWNKVIEQLGTP----VSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYI</Hsp_qseq>
      <Hsp_hseq>AVKEFRTKFENES--KRDYVKKITSEYCIGTTLNHPNIIETIEIVYENDRILQVME--YCEYDLFAIVMSNKMSYEEICCCFKQILTGVQYLHSIGLAHRDLKLDNCVINEKGIVKLIDFGAAVVFSYPFSKNLVEASGIVGSDPYLAPEVCIFAKYDPRPVDIWSSAIIFACMILKKFPWKIPKLRDNSFKLFCSGRD-CDSLSSLVTRTPDPPSYDESHSTEKKKPESSSNNVSDPNNVNIGPQRLLHS--LPEETQH----------IVGRMIDLAPACRGNIEEIMEDPWI</Hsp_hseq>
      <Hsp_midline>A+K+    F+N++  KR + +++    CI   LN  +  ++ E   +   ++ +M+   C+      V+  ++ +E I     Q+L G+++LHS G+ HRDLK  N V+     +K++DFG A   +  F       +  V +  Y APEV +   Y    VDIWS   I   M+                K+   GRD  D  + ++ +   P     S   ++ +P   +   + P       ++L      P +++H          ++ RM+ + P  R  ++E ++ P+I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>6.61834e-12</Hsp_evalue>
      <Hsp_query-from>397</Hsp_query-from>
      <Hsp_query-to>1152</Hsp_query-to>
      <Hsp_hit-from>203</Hsp_hit-from>
      <Hsp_hit-to>446</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>119</Hsp_positive>
      <Hsp_gaps>70</Hsp_gaps>
      <Hsp_align-len>283</Hsp_align-len>
      <Hsp_qseq>QEDFQDVYLVMDLMDAN--LCQVIRMELDHERIS-YLLYQMLCGIKHLHSAGIIHRDLKPSNIVV-------------KSD-----------CSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHVWYDPAEVNGPS----PQISDRRLDEREHTV</Hsp_qseq>
      <Hsp_hseq>QESANYYYLVTELVTGGEIFDRIVQLTCFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLRNNTAKTP-CGTIEYVASEVFTSKRYSMKVDMWSIGCVLFTLL---------------------CGYP--PFYEKNEKTLLKKISR----GDYEFLAPWWDNI-----------SSGAKNAVTHLLEVDPNKRYDIDDFLNDPWLNSYDCLKDSNSNSYASVQSILNDSFDERAETL</Hsp_hseq>
      <Hsp_midline>QE     YLV +L+       +++++    E ++ +++ Q+   IKH+H  GI+HRD+KP N++              K D             +K++DFGLA+    +   TP   T  Y A EV     Y+  VD+WS+GC++  ++                      G P   F ++ + T+   +        Y F   + D +           +S A++ ++ +L +DP KR  +D+ L  P+++ +    + N  S      I +   DER  T+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>9.97279e-12</Hsp_evalue>
      <Hsp_query-from>211</Hsp_query-from>
      <Hsp_query-to>747</Hsp_query-to>
      <Hsp_hit-from>51</Hsp_hit-from>
      <Hsp_hit-to>238</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>192</Hsp_align-len>
      <Hsp_qseq>RPVGSGAQGIV-AAYDTIIDRNVAIK-KLSRPFQ-NQTHAKRAFRELVLMKCIIKLLNVFSPQKSQEDFQDVYLVM------DLMDANLCQVIRMELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNI--VVKSDCS-LKILDFGLART-AATSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCI</Hsp_qseq>
      <Hsp_hseq>RTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKL-SHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEI---IVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGHGKPCDIWSIGVI</Hsp_hseq>
      <Hsp_midline>R +G+G+ G+V  A     + +VAIK  L +  Q N    +  + EL +++ +    N+ S +   E     Y+V       +L D  L +    E+D   I   + Q+L  ++++HS  ++HRDLKP N+  V KS+ S L I DFG+A+       ++     +  Y APEV+   G+ +  DIWS+G I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>1.02619e-11</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>762</Hsp_query-to>
      <Hsp_hit-from>1124</Hsp_hit-from>
      <Hsp_hit-to>1246</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>123</Hsp_align-len>
      <Hsp_qseq>LDHERIS------YLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMT-----------------PYVVTRYYRAPEVILGMGYTENV---DIWSVGCIMGEMV</Hsp_qseq>
      <Hsp_hseq>LDHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMA</Hsp_hseq>
      <Hsp_midline>LDH RI          +++L G+ +LH +G++HRD+KP NI++  +  +K +DFG ART   S   T                   + T  Y APE I G      +   D+W++GC++ EM </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>71</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>1.60894e-11</Hsp_evalue>
      <Hsp_query-from>199</Hsp_query-from>
      <Hsp_query-to>780</Hsp_query-to>
      <Hsp_hit-from>192</Hsp_hit-from>
      <Hsp_hit-to>445</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>64</Hsp_gaps>
      <Hsp_align-len>256</Hsp_align-len>
      <Hsp_qseq>YQNLRPVGSGAQGIVAAYDTIIDRN-----VAIKKLSRP--FQNQTHAKRAFR--------------ELVLMK-----CIIKLLNVFSP--QKSQEDFQDVY-----------LVM------DLMDANLCQVIRMELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSD-------------CS---LKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMGYTENV-DIWSVGCIMGEMVRHKILF</Hsp_qseq>
      <Hsp_hseq>WKKVRPIGSGNFSTVLLYELMDQSNPKLKQVAVKRLKYPEELSNVEQINTSLRYKETLSRLENSLTRELQVLKSLNHPCIVKLLGINNPIFVTSKKPLCDLIIKTPRALPPCDMIMSYCPAGDLLAAVMARNGRLE--AWLIQRIFTEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLCKKIENNEMCTARCGSEDYVSPEILMGVPYDGHLSDTWALGVILYSLFEDRLPF</Hsp_hseq>
      <Hsp_midline>++ +RP+GSG    V  Y+ +   N     VA+K+L  P    N      + R              EL ++K     CI+KLL + +P    S++   D+            ++M      DL+ A + +  R+E     I  +  +++  +K+LH   IIHRDLK  NI++K               C    +++ DFGL +    + M T    +  Y +PE+++G+ Y  ++ D W++G I+  +   ++ F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>72</Hit_num>
  <Hit_id>YAR018C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:170396:171703:-1 gene:YAR018C transcript:YAR018C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN3 description:Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol [Source:SGD;Acc:S000000071]</Hit_def>
  <Hit_accession>YAR018C</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>2.88605e-11</Hsp_evalue>
      <Hsp_query-from>544</Hsp_query-from>
      <Hsp_query-to>927</Hsp_query-to>
      <Hsp_hit-from>170</Hsp_hit-from>
      <Hsp_hit-to>338</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>169</Hsp_align-len>
      <Hsp_qseq>IIHRDLKPSNIVVKSDCS---------------------------------------LKILDFGLARTAATSFMM-TPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKR-LQPTVRNYVETRPRYPGYSFEKL</Hsp_qseq>
      <Hsp_hseq>VIHRDLKPGNIFLSYDDSDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLAKSLETSIQFATTYVGTPYYMSPEVLMDQPYSPLSDIWSLGCVIFEMCSLHPPFQAKNYLELQTKIKNGKCDTVPEYYSRGLNAIIHSMIDVNLRTRPSTFELL</Hsp_hseq>
      <Hsp_midline>+IHRDLKP NI +  D S                                       +K+ DFGLA++  TS    T YV T YY +PEV++   Y+   DIWS+GC++ EM      F  ++Y++   K+       V E+  R L   + + ++   R    +FE L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>73</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>3.93715e-11</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>762</Hsp_query-to>
      <Hsp_hit-from>948</Hsp_hit-from>
      <Hsp_hit-to>1043</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>98</Hsp_align-len>
      <Hsp_qseq>LDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMGYT-ENVDIWSVGCIMGEMV</Hsp_qseq>
      <Hsp_hseq>VEHEA-KLVFKQVVASIKHLHDQGIVHRDIKDENVIVDSHGFVKLIDFGSA-AYIKSGPFDVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLYTII</Hsp_hseq>
      <Hsp_midline>++HE    +  Q++  IKHLH  GI+HRD+K  N++V S   +K++DFG A     S     +V T  Y APEV+ G  Y  +  DIW++G ++  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>74</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>4.24214e-11</Hsp_evalue>
      <Hsp_query-from>322</Hsp_query-from>
      <Hsp_query-to>762</Hsp_query-to>
      <Hsp_hit-from>146</Hsp_hit-from>
      <Hsp_hit-to>295</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>150</Hsp_align-len>
      <Hsp_qseq>KRAFRELVLMKCIIKLLNVFSPQKSQEDFQDVYLVMD-LMDANLCQVIRMELDHERI--SYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMV</Hsp_qseq>
      <Hsp_hseq>QKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELL</Hsp_hseq>
      <Hsp_midline>++ FR  V ++  +   N+        D + VYL+M+ L++  + +++R+      I  S  +YQ+   + ++H   IIHRD+KP NI++  +  +K+ DFG +              T  Y +PE++    Y   +D W++G +  E++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>75</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>5.13699e-11</Hsp_evalue>
      <Hsp_query-from>481</Hsp_query-from>
      <Hsp_query-to>825</Hsp_query-to>
      <Hsp_hit-from>424</Hsp_hit-from>
      <Hsp_hit-to>557</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>134</Hsp_align-len>
      <Hsp_qseq>ERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATS-------------------FMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQ</Hsp_qseq>
      <Hsp_hseq>EDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTK</Hsp_hseq>
      <Hsp_midline>E   +   +++  +++LH  G I+RDLKP NI++     + + DF L+  A  S                   F    +V T  Y APEVI G G+T  VD W++G ++ EM+     F G +  + ++ ++ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>76</Hit_num>
  <Hit_id>YDL025C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:405344:407206:-1 gene:YDL025C transcript:YDL025C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RTK1 description:Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002183]</Hit_def>
  <Hit_accession>YDL025C</Hit_accession>
  <Hit_len>620</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>5.15829e-11</Hsp_evalue>
      <Hsp_query-from>211</Hsp_query-from>
      <Hsp_query-to>1158</Hsp_query-to>
      <Hsp_hit-from>306</Hsp_hit-from>
      <Hsp_hit-to>604</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>331</Hsp_align-len>
      <Hsp_qseq>RPVGSGAQGIVAAYDTIIDRNVAIKKLSRPF-----QNQTHAKRAFRELVLMKCIIKLL---NVFSPQKSQEDFQDVYLVMDLMDANLCQVIRMEL-DHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMT-----PYVVTRYYRAPEVILGMGYTENV-DIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHVWYDPAEVNGPSPQISDRRLDEREHTVDE</Hsp_qseq>
      <Hsp_hseq>RKLGEGASGSVSVVERTDGKLFACKMFRKPHLNNEGTNQSQLANYSKKVTTEFCIGSTLHHENIVETLDMLTEGDTYLLVMEYAPYDFFNLVMSNLMTQDEVNCYFKQLCHGVNYLHSMGLAHRDLKLDNCVVTKDGILKLIDFGSAVVFQYPYEDTIVKSHGIVGSDPYLAPELLKQTSYDPRVADVWSIAIIFYCMVLKR--FPWKAPKKSFNSF-------------RL----------------FTEEPEDEDDIVRGPNKILRLLPRHSRTIIGRMLALEPKQRVLMNDVVKDDWL-VSVPSCEVDPTSGDLVEKPKNHKHHLVTE</Hsp_hseq>
      <Hsp_midline>R +G GA G V+  +    +  A K   +P       NQ+      +++    CI   L   N+        +     LVM+    +   ++   L   + ++    Q+  G+ +LHS G+ HRDLK  N VV  D  LK++DFG A      +  T       V +  Y APE++    Y   V D+WS+  I   MV  +  FP +     +N               RL                ++ E    D +    ++  +L    +R ++ RML ++P +R+ +++ ++  ++ V     EV+  S  + ++  + + H V E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>77</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>6.64027e-11</Hsp_evalue>
      <Hsp_query-from>415</Hsp_query-from>
      <Hsp_query-to>1239</Hsp_query-to>
      <Hsp_hit-from>431</Hsp_hit-from>
      <Hsp_hit-to>663</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>68</Hsp_gaps>
      <Hsp_align-len>288</Hsp_align-len>
      <Hsp_qseq>VYLVMDLMDANLCQVIRME------LDHERISYLLYQMLCGIKHLHSA-GIIHRDLKPSNIVVKSD-CSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMG-----YTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHVWYDPAEVNGPSPQISDRRLDEREHTVDEWKELIYKEVLDWEDRGKNGVAQPTVAL</Hsp_qseq>
      <Hsp_hseq>VYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSANQGTVKLCDFGVSGNLVASLAKT-NIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYPPETYDNIFSQLSAIVDGPP------------------PRLPSDKF-------------------SSDAQDFVSLCLQKIPERRPTYAALTEHPWL-VKYRNQDVHM-SEYITE-RLERRNKILRE--------------RGENGLSKNVPAL</Hsp_hseq>
      <Hsp_midline>VY+ M+ MD      I  E      +D  +++++   ++ G+K L     IIHRD+KP+NI+  ++  ++K+ DFG++     S   T  +  + Y APE I  +      YT   DIWS+G  + EM   +  +P   Y + ++++   +  P                   PR P   F                   +S A+D +S  L   P +R T     +HP++ V Y   +V+  S  I++ RL+ R   + E              RG+NG+++   AL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>78</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>8.15666e-11</Hsp_evalue>
      <Hsp_query-from>148</Hsp_query-from>
      <Hsp_query-to>762</Hsp_query-to>
      <Hsp_hit-from>1249</Hsp_hit-from>
      <Hsp_hit-to>1494</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>53</Hsp_gaps>
      <Hsp_align-len>252</Hsp_align-len>
      <Hsp_qseq>NFYSVEVGDSTFAVCKRYQNLRPVGSGAQG-IVAAYDTIIDRNVAIKKLSRPFQNQTHAKRAFRELVLMKCIIKLLN---VFSPQKSQEDFQDVYLVMDLMDANLCQVIRMELDHERIS-------YLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFM---------------------------------MTPYVVTRYYRAPEVILG---MGYTENVDIWSVGCIMGEMV</Hsp_qseq>
      <Hsp_hseq>NKYLVSLASSISNVSMRWQKRNFIGGGTFGRVYSAVDLDNGEILAVKEIN--IQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAAL---LEHGRIEDEMVTQVYTL-QLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMI</Hsp_hseq>
      <Hsp_midline>N Y V +  S   V  R+Q    +G G  G + +A D      +A+K+++   Q+    ++ F  +     ++++LN   + S    +     V + M+  +      +   L+H RI        Y L Q+L G+ +LH +GI+HRD+KP NI++  +  +K +DFG A+  A +                                   +   + T  Y APE I G    G     D+WS+GC++ EM+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>79</Hit_num>
  <Hit_id>YJL165C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:106894:109461:-1 gene:YJL165C transcript:YJL165C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HAL5 description:Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters; HAL5 has a paralog, KKQ8, that arose from the whole genome duplication [Source:SGD;Acc:S000003701]</Hit_def>
  <Hit_accession>YJL165C</Hit_accession>
  <Hit_len>855</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>1.10787e-10</Hsp_evalue>
      <Hsp_query-from>496</Hsp_query-from>
      <Hsp_query-to>1068</Hsp_query-to>
      <Hsp_hit-from>668</Hsp_hit-from>
      <Hsp_hit-to>837</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>198</Hsp_align-len>
      <Hsp_qseq>LLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSF-----MMTPYVVTRYYRAP-EVILGMGYTEN-VDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYI</Hsp_qseq>
      <Hsp_hseq>FMKQLLNGVQYMHDHGIAHCDLKPENILFQPNGLLKICDFGTSSVFQTAWEKHVHFQSGAMGSEPYVAPEEFIRDAEYDPRLVDCWSCGIVYCTMVMGQYL---------WKIAIPEKDSLFKSFLSEIKDDGQFYLFEELRHVSSELNRLRKIALY-------------------RTFQVDPTKRITIEQLLQSSWM</Hsp_hseq>
      <Hsp_midline> + Q+L G++++H  GI H DLKP NI+ + +  LKI DFG +    T++       +  + +  Y AP E I    Y    VD WS G +   MV  + L         W   I +  +    F+  ++   + Y+    R+      +L   AL+                   R   +DP KRIT+++ LQ  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>80</Hit_num>
  <Hit_id>YFL029C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:78055:79161:-1 gene:YFL029C transcript:YFL029C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CAK1 description:Cyclin-dependent kinase-activating kinase; required for passage through the cell cycle; phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases [Source:SGD;Acc:S000001865]</Hit_def>
  <Hit_accession>YFL029C</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>1.1487e-10</Hsp_evalue>
      <Hsp_query-from>469</Hsp_query-from>
      <Hsp_query-to>756</Hsp_query-to>
      <Hsp_hit-from>126</Hsp_hit-from>
      <Hsp_hit-to>236</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>111</Hsp_align-len>
      <Hsp_qseq>ELDHERISYLLY-QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCS-----LKILDFGLARTAATSFMMTPY--------VVTRYYRAPEVILGMG-YTENVDIWSVGCIMGE</Hsp_qseq>
      <Hsp_hseq>QLDVNRYSLSFFRQMVEGIAFLHENKIIHRDIKPQNIMLTNNTSTVSPKLYIIDFGISYDMANNSQTSAEPMDSKVTDISTGIYKAPEVLFGVKCYDGGVDVWSLLIIISQ</Hsp_hseq>
      <Hsp_midline>+LD  R S   + QM+ GI  LH   IIHRD+KP NI++ ++ S     L I+DFG++   A +   +          + T  Y+APEV+ G+  Y   VD+WS+  I+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>81</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>2.11805e-10</Hsp_evalue>
      <Hsp_query-from>199</Hsp_query-from>
      <Hsp_query-to>825</Hsp_query-to>
      <Hsp_hit-from>496</Hsp_hit-from>
      <Hsp_hit-to>732</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>243</Hsp_align-len>
      <Hsp_qseq>YQNLRPVGSGAQG-IVAAYDTIIDRNVAIKKLSR-PFQNQTHAKRAFRELVLMKC-----IIKLLNVFSPQKSQEDFQDVYLVMDL-MDANLCQVIRME----LDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATS----------------------FMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQ</Hsp_qseq>
      <Hsp_hseq>FEKIRLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQEILATSNHPFIVTLYHSFQ----SEDY--LYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKN</Hsp_hseq>
      <Hsp_midline>++ +R +G G  G +    +   +R  A+K LS+     +   KR   E  ++       I+ L + F      ED+  +YL M+  M     + ++      +  +   +   ++   +++LH  G I+RDLKP NI++     + + DF L+  A  S                      F    +V T  Y APEVI G G+T  VD W++G ++ EM+     F G +  + +  +++ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>82</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>2.19719e-10</Hsp_evalue>
      <Hsp_query-from>496</Hsp_query-from>
      <Hsp_query-to>1095</Hsp_query-to>
      <Hsp_hit-from>155</Hsp_hit-from>
      <Hsp_hit-to>318</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>203</Hsp_align-len>
      <Hsp_qseq>LLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLART-AATSFMMTPYVVTRYYRAPEVILGMGYTE--NVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHVWYDPAEV</Hsp_qseq>
      <Hsp_hseq>LFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYL---------PWDDDHEN---PTGDDIARLY----KYITQTPLK--------FPEYITPI-----------PRDLLRRILVPNPRRRIN----LQTIKRHVWLKPHEA</Hsp_hseq>
      <Hsp_midline>L  Q++ G+ ++H  G++HRDLK  N+++    +L I DFG        + +M     +  Y APE+++     E    D+WS G I+  M+   +          W+   E    P  + + RL      Y+   P          FP+ + P             RDLL R+LV +P +RI     LQ    HVW  P E </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>83</Hit_num>
  <Hit_id>YPR111W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:747306:749000:1 gene:YPR111W transcript:YPR111W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF20 description:Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006315]</Hit_def>
  <Hit_accession>YPR111W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>2.58831e-10</Hsp_evalue>
      <Hsp_query-from>193</Hsp_query-from>
      <Hsp_query-to>786</Hsp_query-to>
      <Hsp_hit-from>167</Hsp_hit-from>
      <Hsp_hit-to>409</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>61</Hsp_gaps>
      <Hsp_align-len>251</Hsp_align-len>
      <Hsp_qseq>KRYQNLRPVGSGAQG-IVAAYDTIIDRNVAIKKLSRPF------QNQTHAKRAFRELVLMKCIIKLLNVFSPQKSQEDFQDVYLVMDLMDAN-----LCQVIRMELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLA--------------RTAATSFMMTPYVVTRY---------------------------YRAPEVILGMGYTENVDIWSVGCIMGEMVRHKILFPG</Hsp_qseq>
      <Hsp_hseq>KDFQILTQVGQGGYGQVYLAKKKDSDEICALKILNKKLLFKLNETNHVLTERDILTTTRSDWLVKLLYAF------QDPESLYLAMEFVPGGDFRTLLINTRILKSGHAR--FYISEMFCAVNALHELGYTHRDLKPENFLIDATGHIKLTDFGLAAGTVSNERIESMKIRLEEVKNLEFPAFTERSIEDRRKIYHNMRKTEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSG</Hsp_hseq>
      <Hsp_midline>K +Q L  VG G  G +  A     D   A+K L++         N    +R          ++KLL  F      +D + +YL M+ +        L     ++  H R  + + +M C +  LH  G  HRDLKP N ++ +   +K+ DFGLA              R      +  P    R                            Y A EV+ G  Y   VD WS+GC++ E +     F G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>84</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>9.81059e-10</Hsp_evalue>
      <Hsp_query-from>154</Hsp_query-from>
      <Hsp_query-to>816</Hsp_query-to>
      <Hsp_hit-from>9</Hsp_hit-from>
      <Hsp_hit-to>279</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>58</Hsp_gaps>
      <Hsp_align-len>275</Hsp_align-len>
      <Hsp_qseq>YSVEVGDSTFAVCKRYQNLRPVGSGAQGIVAAYDTIIDRN--VAIKKLSRP-FQNQTHAKRAFRELVLMKCIIK--LLNVFSPQKSQEDFQDVYLVMD---LMDANLCQVIRMEL-------------------DHERI------SYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS------DCS---------------LKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKV</Hsp_qseq>
      <Hsp_hseq>HTTSVNHNLMASAGNYTAEKEIGKGSFATVYRGHLTSDKSQHVAIKEVSRAKLKNKKLLENLEIEIAILKKIKHPHIVGLIDCERTSTDF---YLIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYL-QQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVVFEMCCGTPPFRASNHLELFKKI</Hsp_hseq>
      <Hsp_midline>++  V  +  A    Y   + +G G+   V       D++  VAIK++SR   +N+   +    E+ ++K I    ++ +   +++  DF   YL+M+   L D       R EL                   +H  +      SYL  Q+   +K L S  ++HRD+KP N+++ +      D                 LKI DFG AR    + +      +  Y APE++    Y    D+WSVG ++ EM      F   ++++ + K+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>85</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.5362</Hsp_bit-score>
      <Hsp_score>140</Hsp_score>
      <Hsp_evalue>1.29942e-09</Hsp_evalue>
      <Hsp_query-from>358</Hsp_query-from>
      <Hsp_query-to>825</Hsp_query-to>
      <Hsp_hit-from>237</Hsp_hit-from>
      <Hsp_hit-to>436</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>56</Hsp_gaps>
      <Hsp_align-len>206</Hsp_align-len>
      <Hsp_qseq>IIKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVIRME---LDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMM-----------------------------------------TPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMVRHKILFPGR------DYIDQWNKVIEQ</Hsp_qseq>
      <Hsp_hseq>LVKLLYAF------QDLQSLYLAMEFVPGGDFRTLLINTRCLKSGHARFYISEMFCAVNALHDLGYTHRDLKPENFLIDAKGHIKLTDFGLAAGTISNERIESMKIRLEKIKDLEFPAFTEKSIEDRRKMYNQLREKEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYDNLRRWKQTLRR</Hsp_hseq>
      <Hsp_midline>++KLL  F      +D Q +YL M+ +     + + +    L      + + +M C +  LH  G  HRDLKP N ++ +   +K+ DFGLA    ++  +                                            V +  Y A EV+ G  Y   VD WS+GC++ E +     F G       D + +W + + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>86</Hit_num>
  <Hit_id>YFL033C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:69115:74427:-1 gene:YFL033C transcript:YFL033C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM15 description:Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase [Source:SGD;Acc:S000001861]</Hit_def>
  <Hit_accession>YFL033C</Hit_accession>
  <Hit_len>1770</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>2.69555e-09</Hsp_evalue>
      <Hsp_query-from>193</Hsp_query-from>
      <Hsp_query-to>633</Hsp_query-to>
      <Hsp_hit-from>792</Hsp_hit-from>
      <Hsp_hit-to>943</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>158</Hsp_align-len>
      <Hsp_qseq>KRYQNLRPVGSGAQGIV-AAYDTIIDRNVAIKKLSRP---FQNQTHAKRAFRELVLMKC----IIKLLNVFSPQKSQEDFQDVYLVMD-LMDANLCQVIRME--LDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTA</Hsp_qseq>
      <Hsp_hseq>KDYDILKPISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDKPYVARLFASF------QNKDNLFLVMEYLPGGDLATLIKMMGYLPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLIDNAGHVKLTDFGLSRAG</Hsp_hseq>
      <Hsp_midline>K Y  L+P+  GA G V  A   +     AIK L +     +NQ    ++ R +++++     + +L   F      ++  +++LVM+ L   +L  +I+M   L  +     L +++ G+  +H  GIIH DLKP N+++ +   +K+ DFGL+R  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>87</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>3.57141e-09</Hsp_evalue>
      <Hsp_query-from>406</Hsp_query-from>
      <Hsp_query-to>816</Hsp_query-to>
      <Hsp_hit-from>519</Hsp_hit-from>
      <Hsp_hit-to>662</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>147</Hsp_align-len>
      <Hsp_qseq>FQDVYLVMDLM--DANLC-----QVI--RMELDHERISYLLYQMLCGIKHLH-SAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKV</Hsp_qseq>
      <Hsp_hseq>FQNSYYIMTELCENGNLDGFLQEQVIAKKKRLEDWRIWKIIVELSLALRFIHDSCHIVHLDLKPANVMITFEGNLKLGDFGMATHLPLEDKSFENEGDREYIAPEIISDCTYDYKADIFSLGLMIVEIAANVVL---PDNGNAWHKL</Hsp_hseq>
      <Hsp_midline>FQ+ Y +M  +  + NL      QVI  +  L+  RI  ++ ++   ++ +H S  I+H DLKP+N+++  + +LK+ DFG+A               R Y APE+I    Y    DI+S+G ++ E+  + +L    D  + W+K+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>88</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>4.32419e-09</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>750</Hsp_query-to>
      <Hsp_hit-from>113</Hsp_hit-from>
      <Hsp_hit-to>212</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>53</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>100</Hsp_align-len>
      <Hsp_qseq>LDHERISYLLYQMLCGIKHLH-SAGIIHRDLKPSNIVVKSDCSLKILDFGLA----RTAATSFMMTPYVVTRYYRAPEVILGMG--YTENVDIWSVGCIM</Hsp_qseq>
      <Hsp_hseq>VDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILL</Hsp_hseq>
      <Hsp_midline>+D +   +   Q++  I +LH   G+ HRD+KP NI++  + +LK+ DFGLA    R   T  +      +  Y APEV+      Y +  DIWS+G ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>89</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>4.04399e-08</Hsp_evalue>
      <Hsp_query-from>358</Hsp_query-from>
      <Hsp_query-to>1056</Hsp_query-to>
      <Hsp_hit-from>385</Hsp_hit-from>
      <Hsp_hit-to>586</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>43</Hsp_gaps>
      <Hsp_align-len>239</Hsp_align-len>
      <Hsp_qseq>IIKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVIRMELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVV-----TRYYRAPEVILGMGYTEN-VDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQ</Hsp_qseq>
      <Hsp_hseq>IVTTLDLF--QDAKGEYCEVMEYCAGGDLFTLVVAAGKLEYMEADCFFKQLIRGVVYMHEMGVCHRDLKPENLLLTHDGVLKITDFGNSECFKMAWEKNIHLSGGVCGSSPYIAPEEYIKEEFDPRPVDIWACGVIYMAMRTGRQLWSSAEKDD---------------------PFYMNYLKGRKEKGGYE----------PIES----LKRARCRNVIYSMLDPVPYRRINGKQILN</Hsp_hseq>
      <Hsp_midline>I+  L++F  Q ++ ++ +V       D     V   +L++        Q++ G+ ++H  G+ HRDLKP N+++  D  LKI DFG +     ++    ++      +  Y APE  +   +    VDIW+ G I   M   + L+   +  D                     P   NY++ R    GY           P +S    LK ++ R+++  ML   P +RI   + L </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>90</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>1.09394e-07</Hsp_evalue>
      <Hsp_query-from>199</Hsp_query-from>
      <Hsp_query-to>780</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>222</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>51</Hsp_gaps>
      <Hsp_align-len>233</Hsp_align-len>
      <Hsp_qseq>YQNLRPVGSGAQGIV-AAYDTIIDRNVAIKKLSRPFQNQTHAKRAFRELVLMKCIIKLLNVFSPQK---SQEDF--QDVYLVM-----------DLMDANLCQVI-----RMELDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVILG-----------------MGYTENVDIWSVGCIMGEMVRHKILF</Hsp_qseq>
      <Hsp_hseq>YTKLRSIQSGTFSTVYKAWSTTHNRYVALKITPKYKTSEANMKNEYD-------VMKILSSCNPHPNICSMLDFYTDDSYYIMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQIDMQKI---IKQLCSAISFAHSLGIAHRDIKPENILLTINGDIKLADWGHAIQSPKSNDFQ--IGTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFGDCLF</Hsp_hseq>
      <Hsp_midline>Y  LR + SG    V  A+ T  +R VA+K   +   ++ + K  +        ++K+L+  +P     S  DF   D Y +M           D +D    Q        +++D ++I   + Q+   I   HS GI HRD+KP NI++  +  +K+ D+G A  +  S      + T  YRAPE   G                 +  T   D WS+G  +  ++    LF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>91</Hit_num>
  <Hit_id>YKL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:347214:349136:-1 gene:YKL048C transcript:YKL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ELM1 description:Serine/threonine protein kinase; regulates the orientation checkpoint, the morphogenesis checkpoint and the metabolic switch from fermentative to oxidative metabolism by phosphorylating the activation loop of Kin4p, Hsl1p and Snf4p respectively; cooperates with Hsl7p in recruiting Hsl1p to the septin ring, a prerequisite for subsequent recruitment, phosphorylation, and degradation of Swe1p; forms part of the bud neck ring; regulates cytokinesis [Source:SGD;Acc:S000001531]</Hit_def>
  <Hit_accession>YKL048C</Hit_accession>
  <Hit_len>640</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>1.23951e-07</Hsp_evalue>
      <Hsp_query-from>496</Hsp_query-from>
      <Hsp_query-to>822</Hsp_query-to>
      <Hsp_hit-from>239</Hsp_hit-from>
      <Hsp_hit-to>368</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>130</Hsp_align-len>
      <Hsp_qseq>LLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSL-KILDFGLARTAATSF-------------MMTPYVVTRYYRAPEVI-LGMGYTENV------DIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIE</Hsp_qseq>
      <Hsp_hseq>ILEDMTKGLEYLHSQGCIHRDIKPSNILLDEEEKVAKLSDFGSCIFTPQSLPFSDANFEDCFQRELNKIVGTPAFIAPELCHLGNSKRDFVTDGFKLDIWSLGVTLYCLLYNELPFFGENEFETYHKIIE</Hsp_hseq>
      <Hsp_midline>+L  M  G+++LHS G IHRD+KPSNI++  +  + K+ DFG       S               +   V T  + APE+  LG    + V      DIWS+G  +  ++ +++ F G +  + ++K+IE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>92</Hit_num>
  <Hit_id>YKL168C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:131288:133462:-1 gene:YKL168C transcript:YKL168C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KKQ8 description:Putative serine/threonine protein kinase with unknown cellular role; KKQ8 has a paralog, HAL5, that arose from the whole genome duplication [Source:SGD;Acc:S000001651]</Hit_def>
  <Hit_accession>YKL168C</Hit_accession>
  <Hit_len>724</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>1.50765e-07</Hsp_evalue>
      <Hsp_query-from>496</Hsp_query-from>
      <Hsp_query-to>1053</Hsp_query-to>
      <Hsp_hit-from>543</Hsp_hit-from>
      <Hsp_hit-to>707</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>194</Hsp_align-len>
      <Hsp_qseq>LLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSF-----MMTPYVVTRYYRAPEVILGMGYTEN--VDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRLQPTVRNYVETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDL-LSRMLVIDPLKRITVDEAL</Hsp_qseq>
      <Hsp_hseq>FMKQLLHGVKFMHDHGIAHCDLKPENILFYPHGLLKICDFGTSSVFQTAWERRVHAQKGIIGSEPYVAPEEFVDGEYYDPRLIDCWSCGVVYITMILGHYL---------WKVASREKDMSYDEFYKEMQRKNQFRV----------FEEL----------KHVNSELATNRKIALYRIFQWEPRKRISVGKLL</Hsp_hseq>
      <Hsp_midline> + Q+L G+K +H  GI H DLKP NI+      LKI DFG +    T++          + +  Y APE  +   Y +   +D WS G +   M+    L         W     +      EF K +Q   +  V          FE+L          +H   + +  R + L R+   +P KRI+V + L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>93</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>2.07102e-07</Hsp_evalue>
      <Hsp_query-from>400</Hsp_query-from>
      <Hsp_query-to>624</Hsp_query-to>
      <Hsp_hit-from>420</Hsp_hit-from>
      <Hsp_hit-to>497</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>25</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>78</Hsp_align-len>
      <Hsp_qseq>EDFQDVYLVMDLMDAN--LCQVIRMELDHERIS-YLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLA</Hsp_qseq>
      <Hsp_hseq>QDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLS</Hsp_hseq>
      <Hsp_midline>+D Q +YL+M+ +     +  +IR +L  E ++ + + + +  I+ +H  G IHRD+KP NI++     +K+ DFGL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>94</Hit_num>
  <Hit_id>YKL198C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:68232:70220:-1 gene:YKL198C transcript:YKL198C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK1 description:Putative serine/threonine protein kinase; regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein; PTK1 has a paralog, PTK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001681]</Hit_def>
  <Hit_accession>YKL198C</Hit_accession>
  <Hit_len>662</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>9.11836e-07</Hsp_evalue>
      <Hsp_query-from>496</Hsp_query-from>
      <Hsp_query-to>624</Hsp_query-to>
      <Hsp_hit-from>309</Hsp_hit-from>
      <Hsp_hit-to>351</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>19</Hsp_identity>
      <Hsp_positive>28</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>43</Hsp_align-len>
      <Hsp_qseq>LLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLA</Hsp_qseq>
      <Hsp_hseq>IFKQVACGVKFCHDQGIAHRDLKPENVLLSPDGVCKLTDFGIS</Hsp_hseq>
      <Hsp_midline>+  Q+ CG+K  H  GI HRDLKP N+++  D   K+ DFG++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>95</Hit_num>
  <Hit_id>YPL026C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:500675:502183:-1 gene:YPL026C transcript:YPL026C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKS1 description:Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway; SKS1 has a paralog, VHS1, that arose from the whole genome duplication [Source:SGD;Acc:S000005947]</Hit_def>
  <Hit_accession>YPL026C</Hit_accession>
  <Hit_len>502</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>9.22208e-07</Hsp_evalue>
      <Hsp_query-from>304</Hsp_query-from>
      <Hsp_query-to>750</Hsp_query-to>
      <Hsp_hit-from>98</Hsp_hit-from>
      <Hsp_hit-to>265</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>169</Hsp_align-len>
      <Hsp_qseq>QNQTHAKRAFRELVLMKCIIKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVI---RMELDHERISYLLYQMLC-GIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVIL--------GMGY--------TENVDIWSVGCIM</Hsp_qseq>
      <Hsp_hseq>ENELNRLPHYREIAFQLRVQSHGNIVKIHQVLESSIATFIVMDYYDRDLFTSIVDDKHFVNHGILIKKVFLQLCSALDHCHRLGIYHCDIKPENVLLDRNDNAYLCDFGLS-TKSKYLAPNVCVGSSYYMAPERILYCLNTTTNGIHVDECCSSLPTDTGDIWSLGIIL</Hsp_hseq>
      <Hsp_midline>+N+ +    +RE+     +    N+    +  E     ++VMD  D +L   I   +  ++H  +   ++  LC  + H H  GI H D+KP N+++  + +  + DFGL+ T +        V + YY APE IL        G+          T+  DIWS+G I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>96</Hit_num>
  <Hit_id>YPL204W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:164276:165760:1 gene:YPL204W transcript:YPL204W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRR25 description:Conserved casein kinase; regulates diverse events including: vesicular traffic, DNA repair, the CVT pathway, monopolar attachment of sister kinetochores at meiosis I, and ribosomal subunit biogenesis; monopolin subunit; binds the RNAPII CTD; phosphorylates COPII coat subunits; interacts with Sit4p phosphatase; antagonizes calcineurin signaling, reducing nuclear accumulation of Crz1p; phosphorylates Dsn1p, the kinetochore receptor for monopolin; homolog of mammalian CK1delta [Source:SGD;Acc:S000006125]</Hit_def>
  <Hit_accession>YPL204W</Hit_accession>
  <Hit_len>494</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.9802</Hsp_bit-score>
      <Hsp_score>110</Hsp_score>
      <Hsp_evalue>4.60872e-06</Hsp_evalue>
      <Hsp_query-from>187</Hsp_query-from>
      <Hsp_query-to>750</Hsp_query-to>
      <Hsp_hit-from>5</Hsp_hit-from>
      <Hsp_hit-to>203</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>207</Hsp_align-len>
      <Hsp_qseq>VCKRYQNLRPVGSGAQG-IVAAYDTIIDRNVAIKKLS-RPFQNQ-THAKRAFRELVLMKCIIKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVIRMELDHERISY-----LLYQMLCGIKHLHSAGIIHRDLKPSNIVV---KSDCSLKILDFGLARTAA--TSFMMTPY------VVTRYYRAPEVILGMGYTENVDIWSVGCIM</Hsp_qseq>
      <Hsp_hseq>VGRKFRIGRKIGSGSFGDIYHGTNLISGEEVAIKLESIRSRHPQLDYESRVYRYLS-GGVGIPFIRWFGREGEYNA-----MVIDLLGPSLEDLF--NYCHRRFSFKTVIMLALQMFCRIQYIHGRSFIHRDIKPDNFLMGVGRRGSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLTGTARYASVNTHLGIEQSRRDDLESLGYVL</Hsp_hseq>
      <Hsp_midline>V ++++  R +GSG+ G I    + I    VAIK  S R    Q  +  R +R L      I  +  F  +          +V+DL+  +L  +      H R S+     L  QM C I+++H    IHRD+KP N ++   +   ++ ++DFGL++      +    PY        T  Y +    LG+  +   D+ S+G ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>97</Hit_num>
  <Hit_id>YJR059W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:545787:548243:1 gene:YJR059W transcript:YJR059W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK2 description:Serine/threonine protein kinase; involved in regulation of ion transport across plasma membrane; carboxyl terminus is essential for glucose-dependent Pma1p activation via phosphorylation of Pma1p-Ser899; enhances spermine uptake; PTK2 has a paralog, PTK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003820]</Hit_def>
  <Hit_accession>YJR059W</Hit_accession>
  <Hit_len>818</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.2098</Hsp_bit-score>
      <Hsp_score>108</Hsp_score>
      <Hsp_evalue>9.58394e-06</Hsp_evalue>
      <Hsp_query-from>130</Hsp_query-from>
      <Hsp_query-to>624</Hsp_query-to>
      <Hsp_hit-from>229</Hsp_hit-from>
      <Hsp_hit-to>410</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>188</Hsp_align-len>
      <Hsp_qseq>PVQEPQNFYSVEVGDSTFAVCKRY---QNLRPVGSGAQGIVAAYDTIIDRN--VAIKKLSRPFQNQTHA--KRAFRELVLMKCI---IKLLNVFSPQK---SQEDFQDVYLVMDLMDANLCQVIRMELDHERISY----------LLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLA</Hsp_qseq>
      <Hsp_hseq>PIANPNDFLPEDMKQYSVHLTDNFVFDTDNKPIGSGGSSEVRKVKSSYRQKDVYALKKLNMIYHESPEKFYKRCSKEFIIAKHLSHNVHITNTFYLLKVPTTTYTTRGWGFIMELGVKDLFQLM------ERTGWKNVPFNEKYCLFKQVAQGIKFCHDNGIAHRDLKPENVLISKEGICKLTDFGIS</Hsp_hseq>
      <Hsp_midline>P+  P +F   ++   +  +   +    + +P+GSG    V    +   +    A+KKL+  +        KR  +E ++ K +   + + N F   K   +    +    +M+L   +L Q++      ER  +          L  Q+  GIK  H  GI HRDLKP N+++  +   K+ DFG++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>98</Hit_num>
  <Hit_id>YBR059C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:356861:360187:-1 gene:YBR059C transcript:YBR059C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AKL1 description:Ser-Thr protein kinase; member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization [Source:SGD;Acc:S000000263]</Hit_def>
  <Hit_accession>YBR059C</Hit_accession>
  <Hit_len>1108</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.2098</Hsp_bit-score>
      <Hsp_score>108</Hsp_score>
      <Hsp_evalue>9.88308e-06</Hsp_evalue>
      <Hsp_query-from>448</Hsp_query-from>
      <Hsp_query-to>780</Hsp_query-to>
      <Hsp_hit-from>143</Hsp_hit-from>
      <Hsp_hit-to>263</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>129</Hsp_align-len>
      <Hsp_qseq>LCQVIRMELDHERISYLLYQMLCGIKHLH--SAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSF----------MMTPYV---VTRYYRAPEVI---LGMGYTENVDIWSVGCIMGEMVRHKILF</Hsp_qseq>
      <Hsp_hseq>MNQRLSTKLTEAEIVKIMYDVALSISQMHYLPVSLIHRDIKIENVLVDAKNNFKLADFG---STSTCFPIVTTHQDIALLTQNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGVFL-----YKLLF</Hsp_hseq>
      <Hsp_midline>+ Q +  +L    I  ++Y +   I  +H     +IHRD+K  N++V +  + K+ DFG   + +T F          ++T  +    T  YR+PE+I     +   E  DIW++G  +     +K+LF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>931228802</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058880-RA transcript Note:&quot;Similar to Fas Tumor necrosis factor receptor superfamily member 6 (Rattus norvegicus)&quot; offset:146 AED:0.03 eAED:0.03 QI:146|0.75|1|1|0.25|0.2|5|4570|258</Iteration_query-def>
  <Iteration_query-len>5493</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>104</Statistics_hsp-len>
      <Statistics_eff-space>3847180909</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058881-RA transcript Note:&quot;Similar to CAMK2D Calcium/calmodulin-dependent protein kinase type II delta chain (Gallus gallus)&quot; offset:0 AED:0.80 eAED:0.80 QI:0|0|0|0.33|1|1|3|0|134</Iteration_query-def>
  <Iteration_query-len>405</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>80</Statistics_hsp-len>
      <Statistics_eff-space>131233685</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058882-RA transcript Note:&quot;Similar to CAMK2D Calcium/calmodulin-dependent protein kinase type II delta chain (Gallus gallus)&quot; offset:0 AED:0.44 eAED:0.44 QI:0|0.5|0.33|0.77|1|1|9|0|293</Iteration_query-def>
  <Iteration_query-len>882</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>100.138</Hsp_bit-score>
      <Hsp_score>248</Hsp_score>
      <Hsp_evalue>2.14195e-24</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>504</Hsp_query-to>
      <Hsp_hit-from>133</Hsp_hit-from>
      <Hsp_hit-to>334</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>206</Hsp_align-len>
      <Hsp_qseq>LHDSISEEGFHYLLFDLHCIQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMW---------------------------------------------ACEAKSLINQMLTINPAKRITASEALTHPWIFQRSTVASCMHRQETVECLKKFNARRKLK</Hsp_qseq>
      <Hsp_hseq>LFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSPFIAESVEGFMEECTASRYPVTFHMPYWDNISIDVKRFILKALRLNPADRPTATELLDDPWITSKRVETSNI----LPDVKKGFSLRKKLR</Hsp_hseq>
      <Hsp_midline>L D I   G    +  +  I QIL AV + H   +VHRDLKPEN+L   K++ + + +ADFG+A +++GE+   +  AG+ GY++PEVL +D +GKP D+W                                             + + K  I + L +NPA R TA+E L  PWI  +    S +      +  K F+ R+KL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>91.2781</Hsp_bit-score>
      <Hsp_score>225</Hsp_score>
      <Hsp_evalue>2.50039e-21</Hsp_evalue>
      <Hsp_query-from>70</Hsp_query-from>
      <Hsp_query-to>420</Hsp_query-to>
      <Hsp_hit-from>139</Hsp_hit-from>
      <Hsp_hit-to>300</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>162</Hsp_align-len>
      <Hsp_qseq>LHCIQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWAC---------------------------------------------EAKSLINQMLTINPAKRITASEALTHPWIF</Hsp_qseq>
      <Hsp_hseq>VRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAELLEDPWII</Hsp_hseq>
      <Hsp_midline>+  + +IL AV + H   IVHRDLKPENLL   K+  + + +ADFG+A  ++ +++  +  AG+ GY++PEVL +D +GKP D+W+                                              +AK  I + L ++P+KR TA+E L  PWI </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>92.0485</Hsp_bit-score>
      <Hsp_score>227</Hsp_score>
      <Hsp_evalue>2.75453e-21</Hsp_evalue>
      <Hsp_query-from>70</Hsp_query-from>
      <Hsp_query-to>417</Hsp_query-to>
      <Hsp_hit-from>217</Hsp_hit-from>
      <Hsp_hit-to>369</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>43</Hsp_gaps>
      <Hsp_align-len>156</Hsp_align-len>
      <Hsp_qseq>LHCIQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPY-GKPVDMWAC---------------------------------------EAKSLINQMLTINPAKRITASEALTHPWI</Hsp_qseq>
      <Hsp_hseq>IHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNR--RIKIADFGMA-ALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMPSNLSSEARDLISKILVIDPEKRITTQEILKHPLI</Hsp_hseq>
      <Hsp_midline>+H  +QI+E V +CH   I HRDLKPENLLL  K +   +K+ADFG+A  ++   +      G+P Y SPE++   PY G P D+W+C                                       EA+ LI+++L I+P KRIT  E L HP I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.6481</Hsp_bit-score>
      <Hsp_score>200</Hsp_score>
      <Hsp_evalue>7.61869e-18</Hsp_evalue>
      <Hsp_query-from>82</Hsp_query-from>
      <Hsp_query-to>417</Hsp_query-to>
      <Hsp_hit-from>301</Hsp_hit-from>
      <Hsp_hit-to>466</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>58</Hsp_gaps>
      <Hsp_align-len>168</Hsp_align-len>
      <Hsp_qseq>QQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLR-------------KDPYGKPVDMWAC-------------------------------------------EAKSLINQMLTINPAKRITASEALTHPWI</Hsp_qseq>
      <Hsp_hseq>RQILTAIKYIHSMGISHRDLKPDNILI-EQDDPVLVKITDFGLA-KVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGPLKDFRISEEARDFIDSLLQVDPNNRSTAAKALNHPWI</Hsp_hseq>
      <Hsp_midline>+QIL A+ + H +GI HRDLKP+N+L+  +     VK+ DFGLA +VQG       F GT  Y++PEV+R             ++ Y   VDMW+                                            EA+  I+ +L ++P  R TA++AL HPWI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.2629</Hsp_bit-score>
      <Hsp_score>199</Hsp_score>
      <Hsp_evalue>1.12766e-17</Hsp_evalue>
      <Hsp_query-from>70</Hsp_query-from>
      <Hsp_query-to>435</Hsp_query-to>
      <Hsp_hit-from>130</Hsp_hit-from>
      <Hsp_hit-to>291</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>166</Hsp_align-len>
      <Hsp_qseq>LHCIQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPY-GKPVDMWAC-------------------------------------------EAKSLINQMLTINPAKRITASEALTHPWIFQRSTV</Hsp_qseq>
      <Hsp_hseq>INCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYN---IKIADFGMA-ALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTI</Hsp_hseq>
      <Hsp_midline>++C +QI+  + +CH LGIVHRDLKPENLLL S      +K+ADFG+A  +Q +        G+P Y +PE++   PY G   D+W+C                                           +A+ LI ++L ++P +RI   + L+HP + +  T+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.7221</Hsp_bit-score>
      <Hsp_score>195</Hsp_score>
      <Hsp_evalue>4.19896e-17</Hsp_evalue>
      <Hsp_query-from>82</Hsp_query-from>
      <Hsp_query-to>411</Hsp_query-to>
      <Hsp_hit-from>138</Hsp_hit-from>
      <Hsp_hit-to>287</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>154</Hsp_align-len>
      <Hsp_qseq>QQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPY-GKPVDMWAC-------------------------------------------EAKSLINQMLTINPAKRITASEALTHP</Hsp_qseq>
      <Hsp_hseq>RQIIIGVSYCHALGIVHRDLKPENLLLDHKYN---IKIADFGMA-ALETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERRIKTRDILKHP</Hsp_hseq>
      <Hsp_midline>+QI+  V +CH LGIVHRDLKPENLLL  K     +K+ADFG+A  ++ E +      G+P Y +PE++   PY G   D+W+C                                           EA+ LI ++LT++P +RI   + L HP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.7962</Hsp_bit-score>
      <Hsp_score>190</Hsp_score>
      <Hsp_evalue>1.23035e-16</Hsp_evalue>
      <Hsp_query-from>82</Hsp_query-from>
      <Hsp_query-to>468</Hsp_query-to>
      <Hsp_hit-from>310</Hsp_hit-from>
      <Hsp_hit-to>500</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>64</Hsp_gaps>
      <Hsp_align-len>192</Hsp_align-len>
      <Hsp_qseq>QQILEAVLHCHQLGIVHRDLKPENLLLASKTK----------------GAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWAC----------------------------EAK----------------SLINQMLTINPAKRITASEALTHPW---IFQRSTVASCMHRQETVE</Hsp_qseq>
      <Hsp_hseq>KQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLA-KFTGEMQFTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVILYVCLCGFPPFSDQLGPPSLKEQILQAKYAFYSPYWDKIDDSVLHLISNLLVLNPDERYNIDEALNHPWFNDIQQQSSVSLELQRLQITD</Hsp_hseq>
      <Hsp_midline>+Q+L  + + H+  I+HRD+KPEN+LL    +                   VK+ADFGLA +  GE Q      GTP Y++PEVL K  Y   VD+W+                             +AK                 LI+ +L +NP +R    EAL HPW   I Q+S+V+  + R +  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.9442</Hsp_bit-score>
      <Hsp_score>180</Hsp_score>
      <Hsp_evalue>2.6716e-15</Hsp_evalue>
      <Hsp_query-from>82</Hsp_query-from>
      <Hsp_query-to>414</Hsp_query-to>
      <Hsp_hit-from>159</Hsp_hit-from>
      <Hsp_hit-to>305</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>151</Hsp_align-len>
      <Hsp_qseq>QQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKP-VDMWAC---------------------------------------EAKSLINQMLTINPAKRITASEALTHPW</Hsp_qseq>
      <Hsp_hseq>QQIISAVEYCHRHKIVHRDLKPENLLL---DEHLNVKIADFGLS-NIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGAAGLIKRMLIVNPLNRISIHEIMQDDW</Hsp_hseq>
      <Hsp_midline>QQI+ AV +CH+  IVHRDLKPENLLL    +   VK+ADFGL+  +  +        G+P Y +PEV+    Y  P VD+W+C                                        A  LI +ML +NP  RI+  E +   W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>3.48392e-14</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>483</Hsp_query-to>
      <Hsp_hit-from>176</Hsp_hit-from>
      <Hsp_hit-to>299</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>134</Hsp_align-len>
      <Hsp_qseq>QILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACEAKSLINQMLT-INPAKRITASEALTHPWIFQRSTVASCMHRQETVECLKKF</Hsp_qseq>
      <Hsp_hseq>EVILALEYLHAHNIIYRDLKPENILL---DRNGHIKITDFGFAKEVQ---TVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGV--LIYEMLAGYTPFYDTTPMK--TYEKILQGKVVYPPYFHPDVVDLLSKL</Hsp_hseq>
      <Hsp_midline>+++ A+ + H   I++RDLKPEN+LL    +   +K+ DFG A EVQ      +   GTP Y++PEV+   PY K VD W+     LI +ML    P    T  +  T+  I Q   V       + V+ L K </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>8.11064e-13</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>327</Hsp_query-to>
      <Hsp_hit-from>1161</Hsp_hit-from>
      <Hsp_hit-to>1289</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>134</Hsp_align-len>
      <Hsp_qseq>HRSNLRLHDSISEEGFHYL------------LFDL-------------HCIQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPY-GKPVDMWA</Hsp_qseq>
      <Hsp_hseq>HENILRLLDFFEDDDYYYIETPVHGETGCIDLFDLIEFKTNMTEFEAKLIFKQVVAGIKHLHDQGIVHRDIKDENVIVDSK---GFVKIIDFGSAAYVK--SGPFDVFVGTIDYAAPEVLGGNPYEGQPQDIWA</Hsp_hseq>
      <Hsp_midline>H + LRL D   ++ ++Y+            LFDL                +Q++  + H H  GIVHRD+K EN+++ SK     VK+ DFG A  V+     +  F GT  Y +PEVL  +PY G+P D+WA</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>1.19854e-12</Hsp_evalue>
      <Hsp_query-from>76</Hsp_query-from>
      <Hsp_query-to>327</Hsp_query-to>
      <Hsp_hit-from>173</Hsp_hit-from>
      <Hsp_hit-to>270</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>99</Hsp_align-len>
      <Hsp_qseq>CIQQILEAVLHCHQLGIVHRDLKPENLLLASKTK--------------GAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEV-LRKDPYGKPVDMWA</Hsp_qseq>
      <Hsp_hseq>ILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVEN-KNPYTAYVSTRWYRSPEILLRSGYYSKPLDIWA</Hsp_hseq>
      <Hsp_midline> + QIL  + H H+    HRDLKPEN+L+   T+                 +KLADFGLA  V+  +  +  +  T  Y SPE+ LR   Y KP+D+WA</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>1.57407e-12</Hsp_evalue>
      <Hsp_query-from>97</Hsp_query-from>
      <Hsp_query-to>360</Hsp_query-to>
      <Hsp_hit-from>198</Hsp_hit-from>
      <Hsp_hit-to>277</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>88</Hsp_align-len>
      <Hsp_qseq>AVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACEAKSLINQML</Hsp_qseq>
      <Hsp_hseq>ALEYLHSKDIIYRDLKPENILL---DKNGHIKITDFGFAKYVP---DVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGV--LIYEML</Hsp_hseq>
      <Hsp_midline>A+ + H   I++RDLKPEN+LL    K   +K+ DFG A  V       +   GTP Y++PEV+   PY K VD W+     LI +ML</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>2.04014e-12</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>360</Hsp_query-to>
      <Hsp_hit-from>932</Hsp_hit-from>
      <Hsp_hit-to>1018</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>97</Hsp_align-len>
      <Hsp_qseq>QILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFG-----FAGTPGYLSPEVLRKDPYGKPVDMWACEAKSLINQML</Hsp_qseq>
      <Hsp_hseq>EVLLALKYFHDNGVIYRDLKLENILL---TPEGHIKIADYGLC-----KDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGV--LLYQML</Hsp_hseq>
      <Hsp_midline>++L A+ + H  G+++RDLK EN+LL   T    +K+AD+GL      + + W+G     F GTP +++PE+L++  Y K VD WA     L+ QML</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>2.29233e-12</Hsp_evalue>
      <Hsp_query-from>97</Hsp_query-from>
      <Hsp_query-to>360</Hsp_query-to>
      <Hsp_hit-from>197</Hsp_hit-from>
      <Hsp_hit-to>276</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>88</Hsp_align-len>
      <Hsp_qseq>AVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACEAKSLINQML</Hsp_qseq>
      <Hsp_hseq>ALEYLHSKDIIYRDLKPENILL---DKNGHIKITDFGFAKYVP---DVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGI--LIYEML</Hsp_hseq>
      <Hsp_midline>A+ + H   I++RDLKPEN+LL    K   +K+ DFG A  V       +   GTP Y++PEV+   PY K +D W+     LI +ML</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>5.71914e-12</Hsp_evalue>
      <Hsp_query-from>82</Hsp_query-from>
      <Hsp_query-to>798</Hsp_query-to>
      <Hsp_hit-from>123</Hsp_hit-from>
      <Hsp_hit-to>383</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>78</Hsp_gaps>
      <Hsp_align-len>289</Hsp_align-len>
      <Hsp_qseq>QQILEAVLHCH-QLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQ---GEQQAWFGFAGTPGYLSPEVLRKDP--YGKPVDMWAC--------------EAKSLINQ------------------------------MLTINPAKRITASEALTHPWIFQRSTVASCMHRQETVECLKKFNARRKLKARKGWEHNVPGLVFEKLCDPGMTSFEPEALGNLVGGMEFHKFYFENLFSKSQRXXXXXXXXXXXXXXGEEAACVAYVRLTQYVDNAGVPRTQQAEETR</Hsp_qseq>
      <Hsp_hseq>QQLVSAINYLHVECGVAHRDIKPENILL---DKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQTPWELPSLENEDFVFFIENDGNLNWGPWSKIEFTHLNLLRKILQPDPNKRVTLKALKLHPWVLRRASFSGDDGLCNDPELL----AKKLFSHLKVSLSNENYLKFTQDTNSNNRYISTQPIGNELAELEHDSMHFQTV-SNTQR------------------AFTSYDSNTNY--NSGTGMTQEAKWTQ</Hsp_hseq>
      <Hsp_midline>QQ++ A+ + H + G+ HRD+KPEN+LL    K   +KLADFGLA + +   G  +      G+P Y++PEVL  +   Y    D+W+               E  SL N+                              +L  +P KR+T      HPW+ +R++ +         E L    A++     K    N   L F +  +        + +GN +  +E    +F+ + S +QR                  A  +Y   T Y  N+G   TQ+A+ T+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>6.33631e-12</Hsp_evalue>
      <Hsp_query-from>82</Hsp_query-from>
      <Hsp_query-to>330</Hsp_query-to>
      <Hsp_hit-from>431</Hsp_hit-from>
      <Hsp_hit-to>515</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>53</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>91</Hsp_align-len>
      <Hsp_qseq>QQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAW-------FGFAGTPGYLSPEVLRKDPYG-KPVDMWAC</Hsp_qseq>
      <Hsp_hseq>KQLIRGVVYMHEMGVCHRDLKPENLLL---THDGVLKITDFG---NSECFKMAWEKNIHLSGGVCGSSPYIAPEEYIKEEFDPRPVDIWAC</Hsp_hseq>
      <Hsp_midline>+Q++  V++ H++G+ HRDLKPENLLL   T    +K+ DFG     +  + AW        G  G+  Y++PE   K+ +  +PVD+WAC</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>6.44341e-12</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>492</Hsp_query-to>
      <Hsp_hit-from>232</Hsp_hit-from>
      <Hsp_hit-to>374</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>151</Hsp_align-len>
      <Hsp_qseq>QILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQ------QAWF-------GFAGTPGYLSPEVLRKDPYGKPVDMWA--CEAKSLINQMLTINPAKRITASEALTHPWIFQRSTVASCMHRQETVECLKKFNAR</Hsp_qseq>
      <Hsp_hseq>QIIDAVDSLHNIGIIHRDIKPENILL---DKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGC----ILYQMLAGKPPFK-AANEYLTFQKVMKIQYAFTAGFPQIVKDLVKKLLVR</Hsp_hseq>
      <Hsp_midline>QI++AV   H +GI+HRD+KPEN+LL    K   VKL DFG A  +  E       + +F        F GT  Y+SPE+L  +      D+WA  C    ++ QML   P  +  A+E LT   + +     +    Q   + +KK   R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>9.82185e-12</Hsp_evalue>
      <Hsp_query-from>79</Hsp_query-from>
      <Hsp_query-to>423</Hsp_query-to>
      <Hsp_hit-from>208</Hsp_hit-from>
      <Hsp_hit-to>357</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>43</Hsp_gaps>
      <Hsp_align-len>154</Hsp_align-len>
      <Hsp_qseq>IQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWAC---------------------------------------EAKSLINQMLTINPAKRITASEALTHPWIFQ</Hsp_qseq>
      <Hsp_hseq>IYQIANALDYMHKKNIIHRDIKPENILIGF---NNVIKLTDFGWSI-INPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMPSNISQDAQDLILKLLKYDPKDRMRLGDVKMHPWILR</Hsp_hseq>
      <Hsp_midline>I QI  A+ + H+  I+HRD+KPEN+L+        +KL DFG +I +   +       GT  YLSPE++    Y   +D WA                                        +A+ LI ++L  +P  R+   +   HPWI +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>1.58795e-11</Hsp_evalue>
      <Hsp_query-from>55</Hsp_query-from>
      <Hsp_query-to>417</Hsp_query-to>
      <Hsp_hit-from>284</Hsp_hit-from>
      <Hsp_hit-to>478</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>78</Hsp_gaps>
      <Hsp_align-len>197</Hsp_align-len>
      <Hsp_qseq>YLLFDL--HCIQQILEAVLHCHQLGIVHRDLKPENLLLA-----------------SKTKG--------------AAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMW-------------------------------------------ACEAKSLINQMLTINPAKRITASEALTHPWI</Hsp_qseq>
      <Hsp_hseq>YFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKNTKT--PCGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTMLCGFPPFYDEKIDTLTEKISRGEYTFLKPWWDEISAGAKNAVAKLLELEPSKRYDIDQFLDDPWL</Hsp_hseq>
      <Hsp_midline>Y   DL  H I+Q+  AV H H LG+VHRD+KPENLL                    +TK                 VKLADFGL+ ++  +        GT GY +PEV++ + Y   VDMW                                           +  AK+ + ++L + P+KR    + L  PW+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>3.72606e-11</Hsp_evalue>
      <Hsp_query-from>79</Hsp_query-from>
      <Hsp_query-to>363</Hsp_query-to>
      <Hsp_hit-from>448</Hsp_hit-from>
      <Hsp_hit-to>537</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>95</Hsp_align-len>
      <Hsp_qseq>IQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACEAKSLINQMLT</Hsp_qseq>
      <Hsp_hseq>IAELLCALDSLHKLDVIYRDLKPENILLDYQ---GHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGI--LLYEMMT</Hsp_hseq>
      <Hsp_midline>I ++L A+   H+L +++RDLKPEN+LL  +     + L DFGL      +      F GTP YL+PE+L    Y K VD W      L+ +M+T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>4.83827e-11</Hsp_evalue>
      <Hsp_query-from>88</Hsp_query-from>
      <Hsp_query-to>423</Hsp_query-to>
      <Hsp_hit-from>253</Hsp_hit-from>
      <Hsp_hit-to>400</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>152</Hsp_align-len>
      <Hsp_qseq>ILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKP-VDMW---------------------------------------ACEAKSLINQMLTINPAKRITASEALTHPWIFQ</Hsp_qseq>
      <Hsp_hseq>IASALIYLHANNIVHRDLKIENIMISDSSE---IKIIDFGLS-NIYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKIKQGKVEYPQHLSIEVISLLSKMLVVDPKRRATLKQVVEHHWMVR</Hsp_hseq>
      <Hsp_midline>I  A+++ H   IVHRDLK EN++++  ++   +K+ DFGL+  +   ++    F G+  + +PE+L+ +PY  P VD+W                                       + E  SL+++ML ++P +R T  + + H W+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>7.21994e-11</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>327</Hsp_query-to>
      <Hsp_hit-from>469</Hsp_hit-from>
      <Hsp_hit-to>567</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>108</Hsp_align-len>
      <Hsp_qseq>RSNLRLHDS-ISEEGFHYLLFDLHCIQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWA</Hsp_qseq>
      <Hsp_hseq>RSNTGEHSSPLNENQMAYI------VKETCQGLKFLHNKKIIHRDIKSDNILLNSQ---GLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWS</Hsp_hseq>
      <Hsp_midline>RSN   H S ++E    Y+      +++  + +   H   I+HRD+K +N+LL S+     VK+ DFG  +E+  ++       GTP +++PE++ +  Y + VD+W+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>7.39912e-11</Hsp_evalue>
      <Hsp_query-from>82</Hsp_query-from>
      <Hsp_query-to>327</Hsp_query-to>
      <Hsp_hit-from>957</Hsp_hit-from>
      <Hsp_hit-to>1034</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>83</Hsp_align-len>
      <Hsp_qseq>QQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPY-GKPVDMWA</Hsp_qseq>
      <Hsp_hseq>KQVVASIKHLHDQGIVHRDIKDENVIVDSH---GFVKLIDFGSAAYIK--SGPFDVFVGTMDYAAPEVLGGSSYKGKPQDIWA</Hsp_hseq>
      <Hsp_midline>+Q++ ++ H H  GIVHRD+K EN+++ S      VKL DFG A  ++     +  F GT  Y +PEVL    Y GKP D+WA</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>9.18952e-11</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>363</Hsp_query-to>
      <Hsp_hit-from>453</Hsp_hit-from>
      <Hsp_hit-to>540</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>93</Hsp_align-len>
      <Hsp_qseq>QILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACEAKSLINQMLT</Hsp_qseq>
      <Hsp_hseq>ELLCALDNLHKLDVVYRDLKPENILLDYQ---GHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGV--LLYEMLT</Hsp_hseq>
      <Hsp_midline>++L A+ + H+L +V+RDLKPEN+LL  +     + L DFGL      +      F GTP YL+PE+L    Y K VD W      L+ +MLT</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>2.21305e-10</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>285</Hsp_query-to>
      <Hsp_hit-from>273</Hsp_hit-from>
      <Hsp_hit-to>339</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>41</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>67</Hsp_align-len>
      <Hsp_qseq>QILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEV</Hsp_qseq>
      <Hsp_hseq>QILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKERMHTVVGTPEYCAPEV</Hsp_hseq>
      <Hsp_midline>QIL+A+ + H   IVHRDLK +N+LL +      + LADFG+A ++   ++      GTP Y +PEV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>2.5523e-10</Hsp_evalue>
      <Hsp_query-from>73</Hsp_query-from>
      <Hsp_query-to>327</Hsp_query-to>
      <Hsp_hit-from>186</Hsp_hit-from>
      <Hsp_hit-to>274</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>53</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>94</Hsp_align-len>
      <Hsp_qseq>HCIQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVL--------RKDPYG-KPVDMWA</Hsp_qseq>
      <Hsp_hseq>HIITQIMDAIEYVHNKGIYHRDIKPENILISGID--WTIKLTDWGLATT---DKTSMDRNVGSERYMSPELFDSNLDIKERKEPYDCAKVDLWA</Hsp_hseq>
      <Hsp_midline>H I QI++A+ + H  GI HRD+KPEN+L++       +KL D+GLA     ++ +     G+  Y+SPE+         RK+PY    VD+WA</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>2.5834e-10</Hsp_evalue>
      <Hsp_query-from>88</Hsp_query-from>
      <Hsp_query-to>417</Hsp_query-to>
      <Hsp_hit-from>232</Hsp_hit-from>
      <Hsp_hit-to>377</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>150</Hsp_align-len>
      <Hsp_qseq>ILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKP-VDMW---------------------------------------ACEAKSLINQMLTINPAKRITASEALTHPWI</Hsp_qseq>
      <Hsp_hseq>IASALQYLHANNIVHRDLKIENIMISSS---GEIKIIDFGLS-NIFDYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYPSHLSIEVISLLTRMIVVDPLRRATLKNVVEHPWM</Hsp_hseq>
      <Hsp_midline>I  A+ + H   IVHRDLK EN++++S      +K+ DFGL+  +   ++    F G+  + +PE+L+  PY  P VD+W                                       + E  SL+ +M+ ++P +R T    + HPW+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>3.85685e-10</Hsp_evalue>
      <Hsp_query-from>73</Hsp_query-from>
      <Hsp_query-to>327</Hsp_query-to>
      <Hsp_hit-from>317</Hsp_hit-from>
      <Hsp_hit-to>400</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>89</Hsp_align-len>
      <Hsp_qseq>HCIQQILEAVL----HCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWA</Hsp_qseq>
      <Hsp_hseq>RVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEK---GEIKLCDFGVSGEAV--NSLAMTFTGTSFYMAPERIQGQPYSVTCDVWS</Hsp_hseq>
      <Hsp_midline>  I +I E+VL    + H+  ++HRD+KP+N+LL  K     +KL DFG++ E          F GT  Y++PE ++  PY    D+W+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.5362</Hsp_bit-score>
      <Hsp_score>140</Hsp_score>
      <Hsp_evalue>4.63123e-10</Hsp_evalue>
      <Hsp_query-from>73</Hsp_query-from>
      <Hsp_query-to>327</Hsp_query-to>
      <Hsp_hit-from>708</Hsp_hit-from>
      <Hsp_hit-to>799</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>95</Hsp_align-len>
      <Hsp_qseq>HCI----------QQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWA</Hsp_qseq>
      <Hsp_hseq>HCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSME---GDIKLTDFGFCAQINELNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWS</Hsp_hseq>
      <Hsp_midline>HCI          ++ L  +   H  G++HRD+K +N+LL+ +     +KL DFG   ++           GTP +++PEV+ +  YG  VD+W+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YNL183C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:293137:295509:-1 gene:YNL183C transcript:YNL183C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NPR1 description:Protein kinase; stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p; negatively regulates Ldb19p-mediated endocytosis through phosphorylation of Ldb19p, which prevents its association with the plasma membrane; Npr1p activity is negatively regulated via phosphorylation by the TOR complex; NPR1 has a paralog, PRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005127]</Hit_def>
  <Hit_accession>YNL183C</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>7.35608e-10</Hsp_evalue>
      <Hsp_query-from>76</Hsp_query-from>
      <Hsp_query-to>327</Hsp_query-to>
      <Hsp_hit-from>541</Hsp_hit-from>
      <Hsp_hit-to>626</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>91</Hsp_align-len>
      <Hsp_qseq>CIQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAI----EVQGEQQAWFGFAGTPGYLSPEV---LRKDPYGKPVDMWA</Hsp_qseq>
      <Hsp_hseq>CFKQILTGVQYLHSIGLAHRDLKLDNCVINEK---GIVKLIDFGAAVVFSYPFSKNLVEASGIVGSDPYLAPEVCIFAKYDP--RPVDIWS</Hsp_hseq>
      <Hsp_midline>C +QIL  V + H +G+ HRDLK +N ++  K     VKL DFG A+              G  G+  YL+PEV    + DP  +PVD+W+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>7.55284e-10</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>360</Hsp_query-to>
      <Hsp_hit-from>432</Hsp_hit-from>
      <Hsp_hit-to>536</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>110</Hsp_align-len>
      <Hsp_qseq>QILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWF------------------GFAGTPGYLSPEVLRKDPYGKPVDMWACEAKSLINQML</Hsp_qseq>
      <Hsp_hseq>EVVAALEYLHLLGFIYRDLKPENILLH---QSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGI--LIYEML</Hsp_hseq>
      <Hsp_midline>+++ A+ + H LG ++RDLKPEN+LL    +   V L+DF L+I+  G ++                      F GT  YL+PEV+R + +   VD W      LI +ML</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>8.06645e-10</Hsp_evalue>
      <Hsp_query-from>76</Hsp_query-from>
      <Hsp_query-to>327</Hsp_query-to>
      <Hsp_hit-from>325</Hsp_hit-from>
      <Hsp_hit-to>407</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>88</Hsp_align-len>
      <Hsp_qseq>CIQQILEAVL----HCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWA</Hsp_qseq>
      <Hsp_hseq>VLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILL---NENGQVKLCDFGVSGEAVNSLAT--TFTGTSFYMAPERIQGQPYSVTSDVWS</Hsp_hseq>
      <Hsp_midline> + +I EAVL    + H+  ++HRD+KP+N+LL    +   VKL DFG++ E          F GT  Y++PE ++  PY    D+W+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>1.00758e-09</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>140</Hsp_hit-from>
      <Hsp_hit-to>344</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>54</Hsp_gaps>
      <Hsp_align-len>209</Hsp_align-len>
      <Hsp_qseq>QILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPY-GKPVDMWAC----------------------------------------EAKSLINQMLTINPAKRITASEALTHPW-------IFQRSTVASCMHRQETVECLKKFNAR--RKLKARKGWEHNVPGLVFEKLCD</Hsp_qseq>
      <Hsp_hseq>QISGAVYYAHSMHCVHRDLKLENILL---DKNGNAKLTDFGFTRECM-TKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDAKVIPDDARDLISRLLAKNPGERPSLSQVLRHPFLQPYGSVVLDQTQKILCRQRSGGTQFKSKLERRLLKRLKQSGVDTQAIKQSILKKKCD</Hsp_hseq>
      <Hsp_midline>QI  AV + H +  VHRDLK EN+LL    K    KL DFG   E    +       GT  Y++PE++ +  Y G  +D+W+                                         +A+ LI+++L  NP +R + S+ L HP+       +  ++    C  R    +   K   R  ++LK        +   + +K CD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>1.02721e-09</Hsp_evalue>
      <Hsp_query-from>10</Hsp_query-from>
      <Hsp_query-to>327</Hsp_query-to>
      <Hsp_hit-from>657</Hsp_hit-from>
      <Hsp_hit-to>753</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>106</Hsp_align-len>
      <Hsp_qseq>SNLRLHDSISEEGFHYLLFDLHCIQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWA</Hsp_qseq>
      <Hsp_hseq>TNDNSHSPLTEPQIAYI------VRETCQGLKFLHDKHIIHRDIKSDNVLLDTR---ARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWS</Hsp_hseq>
      <Hsp_midline>+N   H  ++E    Y+      +++  + +   H   I+HRD+K +N+LL ++   A VK+ DFG    +  ++       GTP +++PEV+++  Y + +D+W+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>1.14244e-09</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>330</Hsp_query-to>
      <Hsp_hit-from>158</Hsp_hit-from>
      <Hsp_hit-to>238</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>QILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPE-VLRKDPY-GKPVDMWAC</Hsp_qseq>
      <Hsp_hseq>QLISGVHYIHSKGLVHRDLKLENLLL---DKNENLVITDFGFVNEFCSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSC</Hsp_hseq>
      <Hsp_midline>Q++  V + H  G+VHRDLK ENLLL    K   + + DFG   E     +      G+P Y +PE V+  +PY  +  D+W+C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>1.24062e-09</Hsp_evalue>
      <Hsp_query-from>73</Hsp_query-from>
      <Hsp_query-to>492</Hsp_query-to>
      <Hsp_hit-from>238</Hsp_hit-from>
      <Hsp_hit-to>426</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>79</Hsp_gaps>
      <Hsp_align-len>204</Hsp_align-len>
      <Hsp_qseq>HCIQQILEAVLHCHQLGIVHRDLKPENLLL---------------------ASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMW-------------------------------------------ACEAKSLINQMLTINPAKRITASEALTHPWIFQRSTVASCMHRQETVECLKKFNAR</Hsp_qseq>
      <Hsp_hseq>HVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLRNNTAK--TPCGTIEYVASEVFTSKRYSMKVDMWSIGCVLFTLLCGYPPFYEKNEKTLLKKISRGDYEFLAPWWDNISSGAKNAVTHLLEVDPNKRYDIDDFLNDPWL-------------NSYDCLKDSNSN</Hsp_hseq>
      <Hsp_midline>H I Q+  A+ H H +GIVHRD+KPENLL                              VKL DFGLA +++          GT  Y++ EV     Y   VDMW                                           +  AK+ +  +L ++P KR    + L  PW+              + +CLK  N+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>1.35068e-09</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>327</Hsp_query-to>
      <Hsp_hit-from>132</Hsp_hit-from>
      <Hsp_hit-to>235</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>114</Hsp_align-len>
      <Hsp_qseq>LHDSISEEGFHYLLFDLHCIQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWF-----------GFAGTPGYLSPEVLRKD-PYGKPVDMWA</Hsp_qseq>
      <Hsp_hseq>IHSSVQLSEFHIKYF----LYQILCGLKYIHSADVIHRDLKPGNILC---TLNGCLKICDFGLA---RGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWA</Hsp_hseq>
      <Hsp_midline>+H S+    FH   F    + QIL  + + H   ++HRDLKP N+L    T    +K+ DFGLA   +G    +F            +  T  Y +PE+L  + PY K VD+WA</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>1.37957e-09</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>372</Hsp_query-to>
      <Hsp_hit-from>116</Hsp_hit-from>
      <Hsp_hit-to>207</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>97</Hsp_align-len>
      <Hsp_qseq>QILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKD-PYGKPVDMWACEAKSLINQMLTINP</Hsp_qseq>
      <Hsp_hseq>QLLQGLAFCHENKILHRDLKPQNLLI---NKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGC--ILAEMITGKP</Hsp_hseq>
      <Hsp_midline>Q+L+ +  CH+  I+HRDLKP+NLL+    K   +KL DFGLA         +     T  Y +P+VL     Y   +D+W+C    ++ +M+T  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>1.69057e-09</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>534</Hsp_query-to>
      <Hsp_hit-from>286</Hsp_hit-from>
      <Hsp_hit-to>459</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>177</Hsp_align-len>
      <Hsp_qseq>QILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWF-----------GFAGTPGYLSPEVLRKDPYGKPVDMWA--CEAKSLI---------NQMLTINPAKRITASEALTHPWIFQ---RSTVASCMHRQETVECLKKFNARRKLKARKG--WEHNVP</Hsp_qseq>
      <Hsp_hseq>QIIDAIDYLHSNGIIHRDIKPENILLDGEMK---IKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKVQYAFTPGFPLIIRDLVKKILVKNLDRRLTISQIKEHHFFKDLNFKDGSVWSKTPP</Hsp_hseq>
      <Hsp_midline>QI++A+ + H  GI+HRD+KPEN+LL  + K   +KL DFG A  +     +              F GT  Y+SPE+L         D+WA  C    +I         N+ LT     ++  +     P I +   +  +   + R+ T+  +K+ +  + L  + G  W    P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>2.43622e-09</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>330</Hsp_query-to>
      <Hsp_hit-from>100</Hsp_hit-from>
      <Hsp_hit-to>209</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>117</Hsp_align-len>
      <Hsp_qseq>LHDSISEEGFHYLLFDLHC---IQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLA----------IEVQGEQQAWFGFAGTPGYLSPEV-LRKDPYGKPVDMWAC</Hsp_qseq>
      <Hsp_hseq>LHRVISTQ----MLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINS---NCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSC</Hsp_hseq>
      <Hsp_midline>LH  IS +    +L D H    I Q L AV   H   ++HRDLKP NLL+ S      +K+ DFGLA           E  G+Q     +  T  Y +PEV L    Y + +D+W+C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>3.16899e-09</Hsp_evalue>
      <Hsp_query-from>73</Hsp_query-from>
      <Hsp_query-to>414</Hsp_query-to>
      <Hsp_hit-from>117</Hsp_hit-from>
      <Hsp_hit-to>249</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>138</Hsp_align-len>
      <Hsp_qseq>HCIQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEV-----------------QGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACEAKSLINQMLTINPA-------KRITASEALTHPW</Hsp_qseq>
      <Hsp_hseq>HFTAQLIDALEFIHSHGIIHRDLKPENVLL---DRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQCGYGSDIWAL--GCMIYQFVQGQPPFRGENELKTFEKIVALDYPW</Hsp_hseq>
      <Hsp_midline>H   Q+++A+   H  GI+HRDLKPEN+LL    +   + + DFG A  +                   + Q    F GT  Y+SPE+L  +  G   D+WA     +I Q +   P        K      AL +PW</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>3.88787e-09</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>414</Hsp_query-to>
      <Hsp_hit-from>187</Hsp_hit-from>
      <Hsp_hit-to>336</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>153</Hsp_align-len>
      <Hsp_qseq>QILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKP--VDMWAC-----------------------------------------EAKSLINQMLTINPAKRITASEALTHPW</Hsp_qseq>
      <Hsp_hseq>QICGAIKYMHSRRVIHRDLKLGNIFFDS---NYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRDKPISDEGKILIRDILSLDPIERPSLTEIMDYVW</Hsp_hseq>
      <Hsp_midline>QI  A+ + H   ++HRDLK  N+   S      +K+ DFGLA  +  E +  +   GTP Y++PEVL     G    VD+W+                                          E K LI  +L+++P +R + +E + + W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YJR059W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:545787:548243:1 gene:YJR059W transcript:YJR059W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK2 description:Serine/threonine protein kinase; involved in regulation of ion transport across plasma membrane; carboxyl terminus is essential for glucose-dependent Pma1p activation via phosphorylation of Pma1p-Ser899; enhances spermine uptake; PTK2 has a paralog, PTK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003820]</Hit_def>
  <Hit_accession>YJR059W</Hit_accession>
  <Hit_len>818</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>3.91462e-09</Hsp_evalue>
      <Hsp_query-from>73</Hsp_query-from>
      <Hsp_query-to>366</Hsp_query-to>
      <Hsp_hit-from>366</Hsp_hit-from>
      <Hsp_hit-to>475</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>113</Hsp_align-len>
      <Hsp_qseq>HCI-QQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAI-------EVQGEQQAWFGFAGTPGYLSPEVLRKDP-------YGKPVDMWACEAKSLINQMLTI</Hsp_qseq>
      <Hsp_hseq>YCLFKQVAQGIKFCHDNGIAHRDLKPENVLIS---KEGICKLTDFGISDWYHVIPHDYTSPVKTCQGMIGSPPYTPPEVMYFDAKKHYPEKFQKPYNPLAMDSYALGIMLITM</Hsp_hseq>
      <Hsp_midline>+C+ +Q+ + +  CH  GI HRDLKPEN+L++   K    KL DFG++        +     +   G  G+P Y  PEV+  D        + KP +  A ++ +L   ++T+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>5.24932e-09</Hsp_evalue>
      <Hsp_query-from>79</Hsp_query-from>
      <Hsp_query-to>372</Hsp_query-to>
      <Hsp_hit-from>127</Hsp_hit-from>
      <Hsp_hit-to>216</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>98</Hsp_align-len>
      <Hsp_qseq>IQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACEAKSLINQMLTINP</Hsp_qseq>
      <Hsp_hseq>VTQTLLGLKYLHGEGVIHRDIKAANILLSADN---TVKLADFGVSTIVNSSA---LTLAGTLNWMAPEILGNRGASTLSDIWSLGAT--VVEMLTKNP</Hsp_hseq>
      <Hsp_midline>+ Q L  + + H  G++HRD+K  N+LL++      VKLADFG++  V          AGT  +++PE+L         D+W+  A   + +MLT NP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YOR267C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:822588:824867:-1 gene:YOR267C transcript:YOR267C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRK1 description:Protein kinase; implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005793]</Hit_def>
  <Hit_accession>YOR267C</Hit_accession>
  <Hit_len>759</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>6.95299e-09</Hsp_evalue>
      <Hsp_query-from>76</Hsp_query-from>
      <Hsp_query-to>327</Hsp_query-to>
      <Hsp_hit-from>320</Hsp_hit-from>
      <Hsp_hit-to>406</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>90</Hsp_align-len>
      <Hsp_qseq>CIQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAI----EVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKP--VDMWA</Hsp_qseq>
      <Hsp_hseq>CLKQLTEGVKYLHSMGLAHRDLKLDNCVMTSQ---GILKLIDFGSAVVFRYPFEDGVTMAHGIVGSDPYLAPEVITSTKSYDPQCVDIWS</Hsp_hseq>
      <Hsp_midline>C++Q+ E V + H +G+ HRDLK +N ++ S+     +KL DFG A+      +       G  G+  YL+PEV+       P  VD+W+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>7.79806e-09</Hsp_evalue>
      <Hsp_query-from>73</Hsp_query-from>
      <Hsp_query-to>330</Hsp_query-to>
      <Hsp_hit-from>123</Hsp_hit-from>
      <Hsp_hit-to>203</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>87</Hsp_align-len>
      <Hsp_qseq>HCIQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRK-DPYGKPVDMWAC</Hsp_qseq>
      <Hsp_hseq>YFLYQILRGLKYVHSAGVIHRDLKPSNILI---NENCDLKICDFGLA-RIQDPQMT--GYVSTRYYRAPEIMLTWQKYDVEVDIWSA</Hsp_hseq>
      <Hsp_midline>+ + QIL  + + H  G++HRDLKP N+L+    +   +K+ DFGLA  +Q  Q    G+  T  Y +PE++     Y   VD+W+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>8.46206e-09</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>474</Hsp_query-to>
      <Hsp_hit-from>1141</Hsp_hit-from>
      <Hsp_hit-to>1329</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>65</Hsp_gaps>
      <Hsp_align-len>192</Hsp_align-len>
      <Hsp_qseq>QILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQG----------------EQQAWFGFAGTPGYLSPEVLR--------------------------KDPYGKPVDMWA--------------------CEAKSLINQMLTINPAKRITASEALTHPWIFQRSTVASCMHRQETVECL</Hsp_qseq>
      <Hsp_hseq>ELLEGLAYLHQSGVVHRDIKPENILLDF---NGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPWSNLDNEWAIMYHVAAGRIPQLPNRDEMTAAGRAFLERCLVQDPTMRATAVELLIDPWMIQIREIAFGNSEKDQVPIL</Hsp_hseq>
      <Hsp_midline>++LE + + HQ G+VHRD+KPEN+LL        +K  DFG A  V G                E ++     GTP Y++PE +                           + P+    + WA                       ++ + + L  +P  R TA E L  PW+ Q   +A     ++ V  L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>8.85608e-09</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>327</Hsp_query-to>
      <Hsp_hit-from>456</Hsp_hit-from>
      <Hsp_hit-to>555</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>104</Hsp_align-len>
      <Hsp_qseq>LHDSISEEGFHYLLFDL--HCIQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWA</Hsp_qseq>
      <Hsp_hseq>LYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDK-PELKIIDFGSSCE---EARTVYTYIQSRFYRAPEIILGIPYSTSIDMWS</Hsp_hseq>
      <Hsp_midline>L++ + +  FH L   L      QIL+++    +  ++H DLKPEN+LL +  K   +K+ DFG + E   E +  + +  +  Y +PE++   PY   +DMW+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>1.02832e-08</Hsp_evalue>
      <Hsp_query-from>79</Hsp_query-from>
      <Hsp_query-to>327</Hsp_query-to>
      <Hsp_hit-from>519</Hsp_hit-from>
      <Hsp_hit-to>597</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>IQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDP-YGKPVDMWA</Hsp_qseq>
      <Hsp_hseq>IAELVLALEHLHDNDIVYRDLKPENILLDA---NGNIALCDFGLSKADLKDRTN--TFCGTTEYLAPELLLDETGYTKMVDFWS</Hsp_hseq>
      <Hsp_midline>I +++ A+ H H   IV+RDLKPEN+LL +      + L DFGL+     ++     F GT  YL+PE+L  +  Y K VD W+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>1.04963e-08</Hsp_evalue>
      <Hsp_query-from>64</Hsp_query-from>
      <Hsp_query-to>330</Hsp_query-to>
      <Hsp_hit-from>148</Hsp_hit-from>
      <Hsp_hit-to>253</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>107</Hsp_align-len>
      <Hsp_qseq>FDLHCIQQILEAVLHCHQLGIVHRDLKPENLLLASKTKG------------------AAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWAC</Hsp_qseq>
      <Hsp_hseq>FVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAE-TLCGSPLYMAPEILNYQKYNAKADLWSV</Hsp_hseq>
      <Hsp_midline>F L  +QQ+  A+       +VHRD+KP+NLLL++   G                    +K+ADFG A  +     A     G+P Y++PE+L    Y    D+W+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>1.44542e-08</Hsp_evalue>
      <Hsp_query-from>91</Hsp_query-from>
      <Hsp_query-to>330</Hsp_query-to>
      <Hsp_hit-from>114</Hsp_hit-from>
      <Hsp_hit-to>191</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>42</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>81</Hsp_align-len>
      <Hsp_qseq>LEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVL-RKDPYGKPVDMWAC</Hsp_qseq>
      <Hsp_hseq>LRGVYHCHRNFILHRDLKPNNLLFSP---DGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSV</Hsp_hseq>
      <Hsp_midline>L  V HCH+  I+HRDLKP NLL +       +K+ADFGLA  +    +       T  Y +PE+L     Y   +D+W+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YKL198C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:68232:70220:-1 gene:YKL198C transcript:YKL198C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK1 description:Putative serine/threonine protein kinase; regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein; PTK1 has a paralog, PTK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001681]</Hit_def>
  <Hit_accession>YKL198C</Hit_accession>
  <Hit_len>662</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>1.4593e-08</Hsp_evalue>
      <Hsp_query-from>76</Hsp_query-from>
      <Hsp_query-to>297</Hsp_query-to>
      <Hsp_hit-from>308</Hsp_hit-from>
      <Hsp_hit-to>386</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>42</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>82</Hsp_align-len>
      <Hsp_qseq>CI-QQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAI-------EVQGEQQAWFGFAGTPGYLSPEVLRKD</Hsp_qseq>
      <Hsp_hseq>CIFKQVACGVKFCHDQGIAHRDLKPENVLLS---PDGVCKLTDFGISDWYHTDPHDLSSPVKKCAGMIGSPPYAPPEVMFYD</Hsp_hseq>
      <Hsp_midline>CI +Q+   V  CH  GI HRDLKPEN+LL+        KL DFG++        ++    +   G  G+P Y  PEV+  D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>1.91344e-08</Hsp_evalue>
      <Hsp_query-from>79</Hsp_query-from>
      <Hsp_query-to>288</Hsp_query-to>
      <Hsp_hit-from>114</Hsp_hit-from>
      <Hsp_hit-to>177</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>40</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>70</Hsp_align-len>
      <Hsp_qseq>IQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVL</Hsp_qseq>
      <Hsp_hseq>IKQLCSAISFAHSLGIAHRDIKPENILL---TINGDIKLADWGHAI--QSPKSNDFQI-GTDNYRAPETF</Hsp_hseq>
      <Hsp_midline>I+Q+  A+   H LGI HRD+KPEN+LL   T    +KLAD+G AI  Q  +   F   GT  Y +PE  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YDL028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:400997:403291:-1 gene:YDL028C transcript:YDL028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MPS1 description:Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]</Hit_def>
  <Hit_accession>YDL028C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>2.16488e-08</Hsp_evalue>
      <Hsp_query-from>49</Hsp_query-from>
      <Hsp_query-to>330</Hsp_query-to>
      <Hsp_hit-from>537</Hsp_hit-from>
      <Hsp_hit-to>640</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>116</Hsp_align-len>
      <Hsp_qseq>FHYLLFDLHCIQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLA-------IEVQGEQQAWFGFAGTPGYLSPEVLRKDPY---------------GKPVDMWAC</Hsp_qseq>
      <Hsp_hseq>FNFVRF---YTKEMLLCIKVVHDAGIVHSDLKPANFVLV---KG-ILKIIDFGIANAVPEHTVNIYRETQ-----IGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSC</Hsp_hseq>
      <Hsp_midline>F+++ F     +++L  +   H  GIVH DLKP N +L    KG  +K+ DFG+A       + +  E Q      GTP Y++PE L    Y               G+P DMW+C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>2.66972e-08</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>408</Hsp_query-to>
      <Hsp_hit-from>604</Hsp_hit-from>
      <Hsp_hit-to>728</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>130</Hsp_align-len>
      <Hsp_qseq>QILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIE--------VQGEQQAWF-------------GFAGTPGYLSPEVLRKDPYGKPVDMWACEAKSLINQML-TINPAKRITASEALTH</Hsp_qseq>
      <Hsp_hseq>EVTAALEYLHLLGFIYRDLKPENILLH---QSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGI--LIYEMLFGFTPFKGDNTNETFTN</Hsp_hseq>
      <Hsp_midline>++  A+ + H LG ++RDLKPEN+LL    +   + L+DF L+I+        V+G  Q+                F GT  Y++PEV+R + +   VD W      LI +ML    P K    +E  T+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YAR018C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:170396:171703:-1 gene:YAR018C transcript:YAR018C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN3 description:Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol [Source:SGD;Acc:S000000071]</Hit_def>
  <Hit_accession>YAR018C</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>2.76741e-08</Hsp_evalue>
      <Hsp_query-from>124</Hsp_query-from>
      <Hsp_query-to>372</Hsp_query-to>
      <Hsp_hit-from>170</Hsp_hit-from>
      <Hsp_hit-to>286</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>119</Hsp_align-len>
      <Hsp_qseq>IVHRDLKPENLLLA-----------------------------SKTKGA-------AVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACEAKSLINQMLTINP</Hsp_qseq>
      <Hsp_hseq>VIHRDLKPGNIFLSYDDSDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLAKSLETSIQFATTYVGTPYYMSPEVLMDQPYSPLSDIWSLGC--VIFEMCSLHP</Hsp_hseq>
      <Hsp_midline>++HRDLKP N+ L+                             S  +G+        VKL DFGLA  ++   Q    + GTP Y+SPEVL   PY    D+W+     +I +M +++P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YMR291W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:852630:854390:1 gene:YMR291W transcript:YMR291W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TDA1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000004905]</Hit_def>
  <Hit_accession>YMR291W</Hit_accession>
  <Hit_len>586</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>3.0289e-08</Hsp_evalue>
      <Hsp_query-from>76</Hsp_query-from>
      <Hsp_query-to>327</Hsp_query-to>
      <Hsp_hit-from>163</Hsp_hit-from>
      <Hsp_hit-to>277</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>118</Hsp_align-len>
      <Hsp_qseq>CIQQILEAVLHCHQLGIVHRDLKPENLLLASKTK-------------------GAAVKLADFGLAIEVQGEQ-QAWFGFAGTPGYLSPEVL--------------RKDPYGKPVDMWA</Hsp_qseq>
      <Hsp_hseq>CLVSVLEFL---HSQGIVHRDLKAENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLVLADFGLAAEYNTSKVNSLKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGCPVDIWA</Hsp_hseq>
      <Hsp_midline>C+  +LE +   H  GIVHRDLK EN+L   +                        + LADFGLA E    +  +   F GT  Y++PE++              + D YG PVD+WA</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>3.66298e-08</Hsp_evalue>
      <Hsp_query-from>79</Hsp_query-from>
      <Hsp_query-to>327</Hsp_query-to>
      <Hsp_hit-from>125</Hsp_hit-from>
      <Hsp_hit-to>205</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>IQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDP-YGKPVDMWA</Hsp_qseq>
      <Hsp_hseq>MRELLVALKCIHKDNVIHRDIKAANVLI---TNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWS</Hsp_hseq>
      <Hsp_midline>++++L A+   H+  ++HRD+K  N+L+   T    VKL DFG+A +V          AGTP +++PEV+ +   Y   VD+W+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YDL025C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:405344:407206:-1 gene:YDL025C transcript:YDL025C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RTK1 description:Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002183]</Hit_def>
  <Hit_accession>YDL025C</Hit_accession>
  <Hit_len>620</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>4.63598e-08</Hsp_evalue>
      <Hsp_query-from>67</Hsp_query-from>
      <Hsp_query-to>327</Hsp_query-to>
      <Hsp_hit-from>406</Hsp_hit-from>
      <Hsp_hit-to>495</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>93</Hsp_align-len>
      <Hsp_qseq>DLHC-IQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWF----GFAGTPGYLSPEVLRKDPYGKPV-DMWA</Hsp_qseq>
      <Hsp_hseq>EVNCYFKQLCHGVNYLHSMGLAHRDLKLDNCVV---TKDGILKLIDFGSAVVFQYPYEDTIVKSHGIVGSDPYLAPELLKQTSYDPRVADVWS</Hsp_hseq>
      <Hsp_midline>+++C  +Q+   V + H +G+ HRDLK +N ++   TK   +KL DFG A+  Q   +       G  G+  YL+PE+L++  Y   V D+W+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YHR079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:258244:261591:-1 gene:YHR079C transcript:YHR079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IRE1 description:Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; role in homeostatic adaptation to ER stress; Kar2p binds inactive Ire1p and releases from it upon ER stress [Source:SGD;Acc:S000001121]</Hit_def>
  <Hit_accession>YHR079C</Hit_accession>
  <Hit_len>1115</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>4.64986e-08</Hsp_evalue>
      <Hsp_query-from>79</Hsp_query-from>
      <Hsp_query-to>432</Hsp_query-to>
      <Hsp_hit-from>778</Hsp_hit-from>
      <Hsp_hit-to>898</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>134</Hsp_align-len>
      <Hsp_qseq>IQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAA----------VKLADFGLAIEVQGEQQAWF----GFAGTPGYLSPEVLRKDPYGKPVDMWACEAKSLINQMLTINPAKR--ITASEALTHPWIFQRST</Hsp_qseq>
      <Hsp_hseq>LRQIASGVAHLHSLKIIHRDLKPQNILVSTSSRFTADQQTGAENLRILISDFGLCKKLDSGQSSFRTNLNNPSGTSGWRAPELLE-------------ESNNLQCQVETEHSSSRHTVVSSDSFYDPFTKRRLT</Hsp_hseq>
      <Hsp_midline>++QI   V H H L I+HRDLKP+N+L+++ ++  A          + ++DFGL  ++   Q ++       +GT G+ +PE+L              E+ +L  Q+ T + + R  + +S++   P+  +R T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>6.56579e-08</Hsp_evalue>
      <Hsp_query-from>88</Hsp_query-from>
      <Hsp_query-to>327</Hsp_query-to>
      <Hsp_hit-from>314</Hsp_hit-from>
      <Hsp_hit-to>389</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>81</Hsp_align-len>
      <Hsp_qseq>ILEAVLHCH-QLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWA</Hsp_qseq>
      <Hsp_hseq>VLNGLDHLYRQYKIIHRDIKPSNVLINSK---GQIKLCDFGVSKKLINS--IADTFVGTSTYMSPERIQGNVYSIKGDVWS</Hsp_hseq>
      <Hsp_midline>+L  + H + Q  I+HRD+KP N+L+ SK     +KL DFG++ ++         F GT  Y+SPE ++ + Y    D+W+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>7.04701e-08</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>438</Hsp_query-to>
      <Hsp_hit-from>1373</Hsp_hit-from>
      <Hsp_hit-to>1565</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>81</Hsp_gaps>
      <Hsp_align-len>196</Hsp_align-len>
      <Hsp_qseq>QILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLA---------------IE-----------------VQGEQQAWFGFAGTPGYLSPE--------------------------VLRKDPYGKPVDMWAC----------------EAKS----LINQMLTINPAKRITASEALTHPWIFQRSTVA</Hsp_qseq>
      <Hsp_hseq>QLLEGLAYLHESGIVHRDVKPENILLDF---NGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPWANLDNEWAIMYHVAAGHTPQFPTKDEVSSAGMKFLERCLIQNPSKRASAVELLMDPWIVQIREIA</Hsp_hseq>
      <Hsp_midline>Q+LE + + H+ GIVHRD+KPEN+LL        +K  DFG A               IE                 V+  + A     GTP Y++PE                          +  + P+    + WA                 E  S     + + L  NP+KR +A E L  PWI Q   +A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>7.57803e-08</Hsp_evalue>
      <Hsp_query-from>73</Hsp_query-from>
      <Hsp_query-to>414</Hsp_query-to>
      <Hsp_hit-from>1282</Hsp_hit-from>
      <Hsp_hit-to>1439</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>161</Hsp_align-len>
      <Hsp_qseq>HCIQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQG-EQQAWFGFAGTPGYLSPEVL-RKDPYGKPVDMWAC---------------------------EAKS----------LINQM--------LTINPAKRITASEALTHPW</Hsp_qseq>
      <Hsp_hseq>HLTTQVLKGLAYLHSKGILHRDMKADNLLL---DQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANELLSHPF</Hsp_hseq>
      <Hsp_midline>H   Q+L+ + + H  GI+HRD+K +NLLL    +    K++DFG++ + +     +     GT  +++PE++  K  Y   VD+W+                            ++KS          LI+Q+          INP KR TA+E L+HP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>9.93852e-08</Hsp_evalue>
      <Hsp_query-from>31</Hsp_query-from>
      <Hsp_query-to>330</Hsp_query-to>
      <Hsp_hit-from>114</Hsp_hit-from>
      <Hsp_hit-to>212</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>108</Hsp_align-len>
      <Hsp_qseq>SISEEGFHYLLFDLHCIQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLA---IEVQGEQQAWFGF----AGTPGYLSPEV-LRKDPYGKPVDMWAC</Hsp_qseq>
      <Hsp_hseq>TLSDDHVQYFTY------QILRALKSIHSAQVIHRDIKPSNLLLNS---NCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSC</Hsp_hseq>
      <Hsp_midline>++S++   Y  +      QIL A+   H   ++HRD+KP NLLL S      +K+ DFGLA         ++   GF      T  Y +PE+ L    Y   +D+W+C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YJL165C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:106894:109461:-1 gene:YJL165C transcript:YJL165C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HAL5 description:Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters; HAL5 has a paralog, KKQ8, that arose from the whole genome duplication [Source:SGD;Acc:S000003701]</Hit_def>
  <Hit_accession>YJL165C</Hit_accession>
  <Hit_len>855</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>1.11932e-07</Hsp_evalue>
      <Hsp_query-from>79</Hsp_query-from>
      <Hsp_query-to>330</Hsp_query-to>
      <Hsp_hit-from>669</Hsp_hit-from>
      <Hsp_hit-to>755</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>90</Hsp_align-len>
      <Hsp_qseq>IQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQG--EQQAWF--GFAGTPGYLSPEVLRKDPYGKP--VDMWAC</Hsp_qseq>
      <Hsp_hseq>MKQLLNGVQYMHDHGIAHCDLKPENILFQP---NGLLKICDFGTSSVFQTAWEKHVHFQSGAMGSEPYVAPEEFIRDAEYDPRLVDCWSC</Hsp_hseq>
      <Hsp_midline>++Q+L  V + H  GI H DLKPEN+L         +K+ DFG +   Q   E+   F  G  G+  Y++PE   +D    P  VD W+C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>1.15901e-07</Hsp_evalue>
      <Hsp_query-from>79</Hsp_query-from>
      <Hsp_query-to>330</Hsp_query-to>
      <Hsp_hit-from>117</Hsp_hit-from>
      <Hsp_hit-to>198</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>85</Hsp_align-len>
      <Hsp_qseq>IQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDP-YGKPVDMWAC</Hsp_qseq>
      <Hsp_hseq>MMQLCKGIAYCHSHRILHRDLKPQNLLI---NKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSI</Hsp_hseq>
      <Hsp_midline>+ Q+ + + +CH   I+HRDLKP+NLL+    K   +KL DFGLA       +A+     T  Y +PEVL     Y   VD W+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>1.83434e-07</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>408</Hsp_query-to>
      <Hsp_hit-from>337</Hsp_hit-from>
      <Hsp_hit-to>462</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>127</Hsp_align-len>
      <Hsp_qseq>QILEAVLHCHQLGIVHRDLKPENLLLASK-------------TKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPY-GKPVDMWACEA--KSLINQMLTINPAKRITA---SEALTH</Hsp_qseq>
      <Hsp_hseq>EVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLCKKIENNEMC-TARCGSEDYVSPEILMGVPYDGHLSDTWALGVILYSLFEDRLPFDPPPNASARQRSRATSH</Hsp_hseq>
      <Hsp_midline>+++ AV + H+  I+HRDLK EN+LL                 K   ++LADFGL  +++  +       G+  Y+SPE+L   PY G   D WA      SL    L  +P    +A   S A +H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>1.86081e-07</Hsp_evalue>
      <Hsp_query-from>79</Hsp_query-from>
      <Hsp_query-to>327</Hsp_query-to>
      <Hsp_hit-from>170</Hsp_hit-from>
      <Hsp_hit-to>261</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>95</Hsp_align-len>
      <Hsp_qseq>IQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLA---------IEVQGEQQAWFGFAGTPGYLSPEVLRKD---PYGKPVDMWA</Hsp_qseq>
      <Hsp_hseq>VLDVVSGLEYLHSQGITHRDIKPSNLLISS---NGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWS</Hsp_hseq>
      <Hsp_midline>+  ++  + + H  GI HRD+KP NLL++S      VK++DFG+A         I+   EQ       GTP + +PE+   +        +D+W+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>2.20788e-07</Hsp_evalue>
      <Hsp_query-from>16</Hsp_query-from>
      <Hsp_query-to>327</Hsp_query-to>
      <Hsp_hit-from>243</Hsp_hit-from>
      <Hsp_hit-to>347</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>53</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>114</Hsp_align-len>
      <Hsp_qseq>LRLHDSISEEGFHYLLFDLHCIQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQ----------QAWFGFAGTPGYLSPEVLRKDPYGKPVDMWA</Hsp_qseq>
      <Hsp_hseq>LKEHGTLDETTVSFYAAEISC------ALRFLHTKGVVYRDLKPENCLL--NQRGHLV-LTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYS</Hsp_hseq>
      <Hsp_midline>L+ H ++ E    +   ++ C      A+   H  G+V+RDLKPEN LL    +G  V L DFGL+ +   +            A +   GTP Y +PE+L    Y +  D ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>2.55436e-07</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>330</Hsp_query-to>
      <Hsp_hit-from>158</Hsp_hit-from>
      <Hsp_hit-to>238</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>44</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>QILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPE-VLRKDPY-GKPVDMWAC</Hsp_qseq>
      <Hsp_hseq>QLISGVNYMHYKGLVHRDLKLENLLL---DKHENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSC</Hsp_hseq>
      <Hsp_midline>Q++  V + H  G+VHRDLK ENLLL    K   + + DFG   E   + +      G+P Y +PE V+    Y  +  D+W+C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>71</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>3.21719e-07</Hsp_evalue>
      <Hsp_query-from>82</Hsp_query-from>
      <Hsp_query-to>330</Hsp_query-to>
      <Hsp_hit-from>561</Hsp_hit-from>
      <Hsp_hit-to>643</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>26</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>86</Hsp_align-len>
      <Hsp_qseq>QQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIE---VQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWAC</Hsp_qseq>
      <Hsp_hseq>RQILIGVAYLHKKNIIHRDIKGANILIDIK---GCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWST</Hsp_hseq>
      <Hsp_midline>+QIL  V + H+  I+HRD+K  N+L+  K     VK+ DFG++ +   +  +Q       G+  ++SPEV+++       D+W+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>72</Hit_num>
  <Hit_id>YDL214C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:74446:76545:-1 gene:YDL214C transcript:YDL214C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR2 description:Serine/threonine protein kinase; inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance; PRR2 has a paralog, NPR1, that arose from the whole genome duplication [Source:SGD;Acc:S000002373]</Hit_def>
  <Hit_accession>YDL214C</Hit_accession>
  <Hit_len>699</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>3.22283e-07</Hsp_evalue>
      <Hsp_query-from>34</Hsp_query-from>
      <Hsp_query-to>327</Hsp_query-to>
      <Hsp_hit-from>451</Hsp_hit-from>
      <Hsp_hit-to>549</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>104</Hsp_align-len>
      <Hsp_qseq>ISEEGFHYLLFDLHCI-QQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLA----IEVQGEQQAWFGFAGTPGYLSPEVLRKDPYG-KPVDMWA</Hsp_qseq>
      <Hsp_hseq>VMSEKMHYE--EICCLFKQLINGVKYLHDIGLSHRDLKLDNCVV---TRRGILKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFYFNEYDPRALDVWS</Hsp_hseq>
      <Hsp_midline>+  E  HY   ++ C+ +Q++  V + H +G+ HRDLK +N ++   T+   +KL DFG +      +  +     G  G+  YLSPEV   + Y  + +D+W+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>73</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>3.43838e-07</Hsp_evalue>
      <Hsp_query-from>13</Hsp_query-from>
      <Hsp_query-to>327</Hsp_query-to>
      <Hsp_hit-from>793</Hsp_hit-from>
      <Hsp_hit-to>910</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>126</Hsp_align-len>
      <Hsp_qseq>NLRLHDSISEEGF------HYLLFDLHCIQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQ--------------GEQQAWFGFAGTPGYLSPEVLR-KDPYGKPVDMWA</Hsp_qseq>
      <Hsp_hseq>NRTLYDLIHSENLNQQRDEYWRLF-----RQILEALSYIHSQGIIHRDLKPMNIFIDESRN---VKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVLDGTGHYNEKIDMYS</Hsp_hseq>
      <Hsp_midline>N  L+D I  E        ++ LF     +QILEA+ + H  GI+HRDLKP N+ +        VK+ DFGLA  V               G         GT  Y++ EVL     Y + +DM++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>74</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>4.4949e-07</Hsp_evalue>
      <Hsp_query-from>73</Hsp_query-from>
      <Hsp_query-to>330</Hsp_query-to>
      <Hsp_hit-from>285</Hsp_hit-from>
      <Hsp_hit-to>367</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>87</Hsp_align-len>
      <Hsp_qseq>HCIQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLR-KDPYGKPVDMWAC</Hsp_qseq>
      <Hsp_hseq>HLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQ---GNLKITDFGLARKMNS-RADYTNRVITLWYRPPELLLGTTNYGTEVDMWGC</Hsp_hseq>
      <Hsp_midline>H  +Q+L  + + H   I+HRD+K  N+L+ ++     +K+ DFGLA ++   +  +     T  Y  PE+L     YG  VDMW C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>75</Hit_num>
  <Hit_id>YFL029C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:78055:79161:-1 gene:YFL029C transcript:YFL029C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CAK1 description:Cyclin-dependent kinase-activating kinase; required for passage through the cell cycle; phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases [Source:SGD;Acc:S000001865]</Hit_def>
  <Hit_accession>YFL029C</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.3654</Hsp_bit-score>
      <Hsp_score>111</Hsp_score>
      <Hsp_evalue>1.29082e-06</Hsp_evalue>
      <Hsp_query-from>64</Hsp_query-from>
      <Hsp_query-to>327</Hsp_query-to>
      <Hsp_hit-from>132</Hsp_hit-from>
      <Hsp_hit-to>229</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>98</Hsp_align-len>
      <Hsp_qseq>FDLHCIQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKL--ADFGLAIEVQGEQQ-------AWFGFAGTPGYLSPEVL-RKDPYGKPVDMWA</Hsp_qseq>
      <Hsp_hseq>YSLSFFRQMVEGIAFLHENKIIHRDIKPQNIMLTNNTSTVSPKLYIIDFGISYDMANNSQTSAEPMDSKVTDISTGIYKAPEVLFGVKCYDGGVDVWS</Hsp_hseq>
      <Hsp_midline>+ L   +Q++E +   H+  I+HRD+KP+N++L + T   + KL   DFG++ ++    Q       +      T  Y +PEVL     Y   VD+W+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>76</Hit_num>
  <Hit_id>YPL026C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:500675:502183:-1 gene:YPL026C transcript:YPL026C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKS1 description:Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway; SKS1 has a paralog, VHS1, that arose from the whole genome duplication [Source:SGD;Acc:S000005947]</Hit_def>
  <Hit_accession>YPL026C</Hit_accession>
  <Hit_len>502</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.9802</Hsp_bit-score>
      <Hsp_score>110</Hsp_score>
      <Hsp_evalue>1.67072e-06</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>282</Hsp_query-to>
      <Hsp_hit-from>169</Hsp_hit-from>
      <Hsp_hit-to>229</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>26</Hsp_identity>
      <Hsp_positive>38</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>66</Hsp_align-len>
      <Hsp_qseq>QILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPE</Hsp_qseq>
      <Hsp_hseq>QLCSALDHCHRLGIYHCDIKPENVLLD---RNDNAYLCDFGLS--TKSKYLAPNVCVGSSYYMAPE</Hsp_hseq>
      <Hsp_midline>Q+  A+ HCH+LGI H D+KPEN+LL    +     L DFGL+   + +  A     G+  Y++PE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>77</Hit_num>
  <Hit_id>YKL168C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:131288:133462:-1 gene:YKL168C transcript:YKL168C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KKQ8 description:Putative serine/threonine protein kinase with unknown cellular role; KKQ8 has a paralog, HAL5, that arose from the whole genome duplication [Source:SGD;Acc:S000001651]</Hit_def>
  <Hit_accession>YKL168C</Hit_accession>
  <Hit_len>724</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.3654</Hsp_bit-score>
      <Hsp_score>111</Hsp_score>
      <Hsp_evalue>1.71183e-06</Hsp_evalue>
      <Hsp_query-from>79</Hsp_query-from>
      <Hsp_query-to>330</Hsp_query-to>
      <Hsp_hit-from>544</Hsp_hit-from>
      <Hsp_hit-to>630</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>43</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>90</Hsp_align-len>
      <Hsp_qseq>IQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQ----AWFGFAGTPGYLSPEVLRKDPYGKP--VDMWAC</Hsp_qseq>
      <Hsp_hseq>MKQLLHGVKFMHDHGIAHCDLKPENILFYPH---GLLKICDFGTSSVFQTAWERRVHAQKGIIGSEPYVAPEEFVDGEYYDPRLIDCWSC</Hsp_hseq>
      <Hsp_midline>++Q+L  V   H  GI H DLKPEN+L         +K+ DFG +   Q   +    A  G  G+  Y++PE      Y  P  +D W+C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>78</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.9802</Hsp_bit-score>
      <Hsp_score>110</Hsp_score>
      <Hsp_evalue>2.11986e-06</Hsp_evalue>
      <Hsp_query-from>49</Hsp_query-from>
      <Hsp_query-to>213</Hsp_query-to>
      <Hsp_hit-from>262</Hsp_hit-from>
      <Hsp_hit-to>322</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>33</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>64</Hsp_align-len>
      <Hsp_qseq>FHYLLFDLHC---------IQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLA</Hsp_qseq>
      <Hsp_hseq>FRTLLINTRCLKSGHARFYISEMFCAVNALHDLGYTHRDLKPENFLIDAK---GHIKLTDFGLA</Hsp_hseq>
      <Hsp_midline>F  LL +  C         I ++  AV   H LG  HRDLKPEN L+ +K     +KL DFGLA</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>79</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.2098</Hsp_bit-score>
      <Hsp_score>108</Hsp_score>
      <Hsp_evalue>2.5441e-06</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>327</Hsp_query-to>
      <Hsp_hit-from>147</Hsp_hit-from>
      <Hsp_hit-to>225</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>26</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>82</Hsp_align-len>
      <Hsp_qseq>QILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPE-VLRKDPYGKPVDMWA</Hsp_qseq>
      <Hsp_hseq>QIARGMLYLHGLGVCHRDIKPSNVLVDPET--GVLKICDFGSAKKLEHNQPS-ISYICSRFYRAPELIIGCTQYTTQIDIWG</Hsp_hseq>
      <Hsp_midline>QI   +L+ H LG+ HRD+KP N+L+  +T    +K+ DFG A +++  Q +   +  +  Y +PE ++    Y   +D+W </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>80</Hit_num>
  <Hit_id>YIL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:287790:288908:-1 gene:YIL035C transcript:YIL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA1 description:Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000001297]</Hit_def>
  <Hit_accession>YIL035C</Hit_accession>
  <Hit_len>372</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.8246</Hsp_bit-score>
      <Hsp_score>107</Hsp_score>
      <Hsp_evalue>3.28469e-06</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>213</Hsp_query-to>
      <Hsp_hit-from>178</Hsp_hit-from>
      <Hsp_hit-to>218</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>19</Hsp_identity>
      <Hsp_positive>33</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>43</Hsp_align-len>
      <Hsp_qseq>QILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLA</Hsp_qseq>
      <Hsp_hseq>ELLKALDYCHSMGIMHRDVKPHNVMIDHKNK--KLRLIDWGLA</Hsp_hseq>
      <Hsp_midline>++L+A+ +CH +GI+HRD+KP N+++  K K   ++L D+GLA</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>81</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.8246</Hsp_bit-score>
      <Hsp_score>107</Hsp_score>
      <Hsp_evalue>3.9869e-06</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>330</Hsp_query-to>
      <Hsp_hit-from>269</Hsp_hit-from>
      <Hsp_hit-to>351</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>86</Hsp_align-len>
      <Hsp_qseq>QILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFG---FAGTPGYLSPEVLRKDPYGKP-VDMWAC</Hsp_qseq>
      <Hsp_hseq>QLLDGVSYLHQNWVLHRDLKPANIMV---TIDGCVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSV</Hsp_hseq>
      <Hsp_midline>Q+L+ V + HQ  ++HRDLKP N+++   T    VK+ D GLA +     Q  +       T  Y +PE+L    +  P VD+W+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>82</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.8246</Hsp_bit-score>
      <Hsp_score>107</Hsp_score>
      <Hsp_evalue>4.96457e-06</Hsp_evalue>
      <Hsp_query-from>79</Hsp_query-from>
      <Hsp_query-to>327</Hsp_query-to>
      <Hsp_hit-from>122</Hsp_hit-from>
      <Hsp_hit-to>202</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>26</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>85</Hsp_align-len>
      <Hsp_qseq>IQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVL--RKDPYGKPVDMWA</Hsp_qseq>
      <Hsp_hseq>IHEVTLGLKYLHEQRKIHRDIKAANILLNEE---GMVKLGDFGVSGHIRSTLKRD-TFVGTPYWMAPEVVCCEVDGYNEKADIWS</Hsp_hseq>
      <Hsp_midline>I ++   + + H+   +HRD+K  N+LL  +     VKL DFG++  ++   +    F GTP +++PEV+    D Y +  D+W+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>83</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>44.669</Hsp_bit-score>
      <Hsp_score>104</Hsp_score>
      <Hsp_evalue>8.7072e-06</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>372</Hsp_query-to>
      <Hsp_hit-from>156</Hsp_hit-from>
      <Hsp_hit-to>247</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>99</Hsp_align-len>
      <Hsp_qseq>QILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLA--IEVQGEQQAWFGFAGTPGYLSPE-VLRKDPYGKPVDMWACEAKSLINQMLTINP</Hsp_qseq>
      <Hsp_hseq>QILRALLTLHSMSICHGDLKPSNILIIPSS--GIAKVCDFGSAQRLDDNTELKTYF---CSRFYRAPELLLNSKDYTTQIDIWSLGC--IIGEMIKGQP</Hsp_hseq>
      <Hsp_midline>QIL A+L  H + I H DLKP N+L+   +     K+ DFG A  ++   E + +F    +  Y +PE +L    Y   +D+W+     +I +M+   P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>89</Statistics_hsp-len>
      <Statistics_eff-space>476966735</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0046405-RA transcript Note:&quot;Similar to C1qtnf9 Complement C1q and tumor necrosis factor-related protein 9 (Mus musculus)&quot; offset:0 AED:0.14 eAED:0.14 QI:0|0|0|1|0|0|2|0|175</Iteration_query-def>
  <Iteration_query-len>528</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>83</Statistics_hsp-len>
      <Statistics_eff-space>220062831</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058883-RA transcript Note:&quot;Similar to Dcst1 E3 ubiquitin-protein ligase DCST1 (Mus musculus)&quot; offset:0 AED:0.07 eAED:0.07 QI:0|0.33|0.5|0.75|1|1|4|457|497</Iteration_query-def>
  <Iteration_query-len>1951</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1263378718</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0046406-RA transcript Note:&quot;Similar to zgc:153146 UPF0602 protein C4orf47 homolog (Danio rerio)&quot; offset:154 AED:0.06 eAED:0.06 QI:154|1|0.87|1|0.14|0.12|8|811|316</Iteration_query-def>
  <Iteration_query-len>1916</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1236013114</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058887-RA transcript Note:&quot;Protein of unknown function&quot; offset:328 AED:0.14 eAED:0.14 QI:328|0.8|0.83|1|0.6|0.33|6|3613|336</Iteration_query-def>
  <Iteration_query-len>4952</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3456411049</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

