<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0051908-RA transcript Note:&quot;Similar to Nxph1 Neurexophilin-1 (Rattus norvegicus)&quot; offset:325 AED:0.05 eAED:0.05 QI:325|1|1|1|0|0.33|3|1820|267</BlastOutput_query-def>
  <BlastOutput_query-len>2949</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0051908-RA transcript Note:&quot;Similar to Nxph1 Neurexophilin-1 (Rattus norvegicus)&quot; offset:325 AED:0.05 eAED:0.05 QI:325|1|1|1|0|0.33|3|1820|267</Iteration_query-def>
  <Iteration_query-len>2949</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>1998429628</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0051905-RA transcript Note:&quot;Similar to Arhgap15 Rho GTPase-activating protein 15 (Mus musculus)&quot; offset:0 AED:0.79 eAED:0.79 QI:0|0.33|0.42|0.57|0.83|0.71|7|0|423</Iteration_query-def>
  <Iteration_query-len>1272</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>92</Statistics_hsp-len>
      <Statistics_eff-space>765879844</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0027266-RA transcript Note:&quot;Similar to thsd7aa Thrombospondin type-1 domain-containing protein 7A (Danio rerio)&quot; offset:0 AED:0.40 eAED:0.40 QI:0|0.11|0.1|0.6|0|0.2|10|693|390</Iteration_query-def>
  <Iteration_query-len>1866</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1199525642</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0005560-RA transcript Note:&quot;Similar to Adarb2 Double-stranded RNA-specific editase B2 (Rattus norvegicus)&quot; offset:0 AED:0.36 eAED:0.41 QI:0|-1|0|1|-1|1|1|0|396</Iteration_query-def>
  <Iteration_query-len>1191</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>92</Statistics_hsp-len>
      <Statistics_eff-space>703594435</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0051942-RA transcript Note:&quot;Similar to NRP2 Neuropilin-2 (Homo sapiens)&quot; offset:1391 AED:0.30 eAED:0.30 QI:1391|0.66|0.71|1|0.83|0.71|7|0|356</Iteration_query-def>
  <Iteration_query-len>2462</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1636966774</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0041375-RA transcript Note:&quot;Protein of unknown function&quot; offset:38 AED:0.26 eAED:0.26 QI:38|0.45|0.41|1|0|0|12|3166|642</Iteration_query-def>
  <Iteration_query-len>5133</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3592701336</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0051946-RA transcript Note:&quot;Similar to slc40a1 Solute carrier family 40 member 1 (Danio rerio)&quot; offset:0 AED:0.17 eAED:0.17 QI:0|0|0|0.8|1|1|5|0|447</Iteration_query-def>
  <Iteration_query-len>1344</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>93</Statistics_hsp-len>
      <Statistics_eff-space>816594785</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0051947-RA transcript Note:&quot;Similar to CDK2 Cyclin-dependent kinase 2 (Mesocricetus auratus)&quot; offset:275 AED:0.33 eAED:0.33 QI:275|0.88|0.9|1|0.22|0.2|10|113|545</Iteration_query-def>
  <Iteration_query-len>2026</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>358.992</Hsp_bit-score>
      <Hsp_score>920</Hsp_score>
      <Hsp_evalue>2.979e-120</Hsp_evalue>
      <Hsp_query-from>264</Hsp_query-from>
      <Hsp_query-to>1064</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>272</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>173</Hsp_identity>
      <Hsp_positive>215</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>273</Hsp_align-len>
      <Hsp_qseq>LRAAMDNFQKVEKIGEGTYGVVYKARNKLTGEA---VALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSE-KKLYLVFELLDQDLKKFMDNATPSGIPL--PLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVSQLPDYKSTFPRWANQELTKVVPTLNFEGRDLL</Hsp_qseq>
      <Hsp_hseq>MSGELANYKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYME-GIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIVYLPDFKPSFPQWRRKDLSQVVPSLDPRGIDLL</Hsp_hseq>
      <Hsp_midline>+   + N++++EK+GEGTYGVVYKA +   G+    VALKKIRL++E EGVPSTAIREISLL+EL   NIVRL  I+HS+  KLYLVFE LD DLK++M+   P   PL   +VK ++ QL +GIA+CHSHRILHRDLKPQNLLIN +G +KL DFGLARAFGVP R YTHE+VTLWYRAPE+LLG K YST VD WSIGCIFAEM  R+ +F GDSEIDQ+F+IFR LGTP+E +WP +  LPD+K +FP+W  ++L++VVP+L+  G DLL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>310.842</Hsp_bit-score>
      <Hsp_score>795</Hsp_score>
      <Hsp_evalue>1.47632e-101</Hsp_evalue>
      <Hsp_query-from>270</Hsp_query-from>
      <Hsp_query-to>1031</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>258</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>147</Hsp_identity>
      <Hsp_positive>195</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>258</Hsp_align-len>
      <Hsp_qseq>AAMDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDN----ATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVSQLPDYKSTFPRWANQELTKVV</Hsp_qseq>
      <Hsp_hseq>SSSSQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPKYNPNIQQRPPRDLRQVL</Hsp_hseq>
      <Hsp_midline>++   F+++EK+G GTY  VYK  NK TG  VALK+++LD+E EG PSTAIREISL++EL H NIVRL  +IH+E KL LVFE +D DLKK+MD+     TP G+ L LVK + +QLLQG+AFCH ++ILHRDLKPQNLLIN  G +KL DFGLARAFG+P  T++ EVVTLWYRAP++L+G + YSTS+D+WS GCI AEM+T + LFPG ++ +QL  IF  +GTP+E +WP V++LP Y     +   ++L +V+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>216.083</Hsp_bit-score>
      <Hsp_score>549</Hsp_score>
      <Hsp_evalue>2.95725e-65</Hsp_evalue>
      <Hsp_query-from>285</Hsp_query-from>
      <Hsp_query-to>1025</Hsp_query-to>
      <Hsp_hit-from>7</Hsp_hit-from>
      <Hsp_hit-to>254</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>106</Hsp_identity>
      <Hsp_positive>153</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>249</Hsp_align-len>
      <Hsp_qseq>FQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVSQLPDYK--STFPRWANQELTK</Hsp_qseq>
      <Hsp_hseq>YTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNVIELIDIFMAYDNLNLVLEFLPTDLEVVIKDKSILFTPAD-IKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDRDWPEVSSFMTYNKLQIYPPPSRDELRK</Hsp_hseq>
      <Hsp_midline>+ K +K+GEGTY VVY      TG  +A+K+I+     +G+  +AIRE+  L+E+ HPN++ L+ I  +   L LV E L  DL+  + + +    P   +K+++   L+G+  CH + ILHRDLKP NLL + +G IK+ADFGLARA   P    T  VVT WYRAPE+L G KHY++++D+WS+G IFAE++ R    PG +++DQ+   FR LGTP +  WP VS    Y     +P  +  EL K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>211.846</Hsp_bit-score>
      <Hsp_score>538</Hsp_score>
      <Hsp_evalue>3.65924e-61</Hsp_evalue>
      <Hsp_query-from>285</Hsp_query-from>
      <Hsp_query-to>1064</Hsp_query-to>
      <Hsp_hit-from>183</Hsp_hit-from>
      <Hsp_hit-to>437</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>107</Hsp_identity>
      <Hsp_positive>160</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>261</Hsp_align-len>
      <Hsp_qseq>FQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTI-IHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVSQLPDYKSTFPRWANQELTKVVPTLNFEGRDLL</Hsp_qseq>
      <Hsp_hseq>YLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNVSTIKEIMVESQKTVYMIFEYADNDLSGLLLNKEVQ-ISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKMN-SRADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTPTINSWPTLYDMPWFFMIMP----QQTTKYVNNFSEKFKSVL</Hsp_hseq>
      <Hsp_midline>+ ++ ++GEGTYG VYKA+N  T + VALKK+RL  E EG P T+IREI LL+  +HPN+  +  I + S+K +Y++FE  D DL   + N     I     K    QLL G+ + H ++ILHRD+K  N+LI+ +G +K+ DFGLAR     +  YT+ V+TLWYR PE+LLG  +Y T VD+W  GC+  E+  + A+F G +E++Q+  IF+ +GTP    WP +  +P +    P    Q+ TK V   + + + +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>183.341</Hsp_bit-score>
      <Hsp_score>464</Hsp_score>
      <Hsp_evalue>4.78636e-50</Hsp_evalue>
      <Hsp_query-from>276</Hsp_query-from>
      <Hsp_query-to>977</Hsp_query-to>
      <Hsp_hit-from>57</Hsp_hit-from>
      <Hsp_hit-to>314</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>96</Hsp_identity>
      <Hsp_positive>150</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>259</Hsp_align-len>
      <Hsp_qseq>MDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSE-------------KKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLAR-AFGVPQR-----------TYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVSQLP</Hsp_qseq>
      <Hsp_hseq>QNHYREDEKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPR-INLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTEEDWAVARYLP</Hsp_hseq>
      <Hsp_midline> +++++ EK+G+GT+G VYK  +  T   VA+KKI +  E +  P TA REI++L+ LNH NI++L+ +++               K  Y++   +  DL   + N     + +  +K+ + Q+L+G+ + H  + +HRD+K  N+LI+  G +KLADFGLAR  +G P              YT  VVT WYRAPE++LG K Y+T+VD+W +GC+FAE   ++ +  G ++IDQ   IF+ LGTP E  W     LP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>175.637</Hsp_bit-score>
      <Hsp_score>444</Hsp_score>
      <Hsp_evalue>5.79935e-48</Hsp_evalue>
      <Hsp_query-from>402</Hsp_query-from>
      <Hsp_query-to>1004</Hsp_query-to>
      <Hsp_hit-from>199</Hsp_hit-from>
      <Hsp_hit-to>418</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>85</Hsp_identity>
      <Hsp_positive>141</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>220</Hsp_align-len>
      <Hsp_qseq>GVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKK---FMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAF-GVPQRTYTHE--VVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDS-----------EIDQLFRIFRTLGTPDEVVWPGVSQLPDYK--STFPRW</Hsp_qseq>
      <Hsp_hseq>GISQSACREMALCRELHNKHLTTLVEIFLERKCVHMVYEYAEHDLLQIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDGCVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELIGLQPIFKGEEAKLDSKKTVPFQVNQLQRILEVLGTPDQKIWPYLEKYPEYDQITKFPKY</Hsp_hseq>
      <Hsp_midline>G+  +A RE++L REL++ ++  L+ I    K +++V+E  + DL +   F  +     IP  +V+S ++QLL G+++ H + +LHRDLKP N+++  +G +K+ D GLAR F  + Q  YT +  VVT+WYRAPE+LLG +HY+ +VD+WS+GCIFAE++  + +F G+            +++QL RI   LGTPD+ +WP + + P+Y   + FP++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>164.466</Hsp_bit-score>
      <Hsp_score>415</Hsp_score>
      <Hsp_evalue>1.12062e-45</Hsp_evalue>
      <Hsp_query-from>282</Hsp_query-from>
      <Hsp_query-to>1064</Hsp_query-to>
      <Hsp_hit-from>12</Hsp_hit-from>
      <Hsp_hit-to>286</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>102</Hsp_identity>
      <Hsp_positive>147</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>282</Hsp_align-len>
      <Hsp_qseq>NFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIR---EISLLRELNHPNIVRLLTI-----IHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVP----------QRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTP---DEVVWPGVSQLPDYKSTFPRWANQELTKVVPTLNFEGRDLL</Hsp_qseq>
      <Hsp_hseq>DFQLKSLLGEGAYGVVCSATHKPTGEIVAIKKI----EPFDKPLFALRTLREIKILKHFKHENIITIFNIQRPDSFENFNEVYIIQELMQTDLHRVISTQMLSD---DHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHSDNDLRCIESPRAREYIKSLPMYPAAPLEKMFPRVNPKGIDLL</Hsp_hseq>
      <Hsp_midline>+FQ    +GEG YGVV  A +K TGE VA+KKI    E    P  A+R   EI +L+   H NI+ +  I       +  ++Y++ EL+  DL + +     S      ++ ++YQ L+ +   H   ++HRDLKP NLLIN+   +K+ DFGLAR               Q   T  V T WYRAPE++L    YS ++DVWS GCI AE+  RR +FPG     QL  IF  +GTP   +++      +  +Y  + P +    L K+ P +N +G DLL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>159.073</Hsp_bit-score>
      <Hsp_score>401</Hsp_score>
      <Hsp_evalue>1.44226e-43</Hsp_evalue>
      <Hsp_query-from>282</Hsp_query-from>
      <Hsp_query-to>941</Hsp_query-to>
      <Hsp_hit-from>12</Hsp_hit-from>
      <Hsp_hit-to>245</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>95</Hsp_identity>
      <Hsp_positive>138</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>235</Hsp_align-len>
      <Hsp_qseq>NFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELN-HPNIVRLL-----TIIHSEKKLYLVFELLDQDLKKFMDNATP--SGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRT-------YTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTP</Hsp_qseq>
      <Hsp_hseq>QYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRT-IREIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTP</Hsp_hseq>
      <Hsp_midline> ++ V+ IGEG YG V  A +K +G  VA+KKI+  ++   V  T IREI LLR  + H NI+ +L       I     +YLV EL++ DL+K ++N     S +    V+ + YQ+L+ +   HS +++HRD+KP NLL+N+   +K+ DFGLAR       +        T  V T WYRAPEI+L  + Y+T++D+WS GCI AEM++ + LFPG     QL+ I   LGTP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>153.68</Hsp_bit-score>
      <Hsp_score>387</Hsp_score>
      <Hsp_evalue>4.01024e-41</Hsp_evalue>
      <Hsp_query-from>285</Hsp_query-from>
      <Hsp_query-to>941</Hsp_query-to>
      <Hsp_hit-from>23</Hsp_hit-from>
      <Hsp_hit-to>236</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>87</Hsp_identity>
      <Hsp_positive>124</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>222</Hsp_align-len>
      <Hsp_qseq>FQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSE-KKLYLVFELLDQDLKKFMDNATPSGIPLP--LVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTP</Hsp_qseq>
      <Hsp_hseq>YNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLSPLEDIYFVTELQGTDLHRLLQTR-----PLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLAR---IQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSP</Hsp_hseq>
      <Hsp_midline>+  +  +G G +G+V  A + LT + VA+KKI     T  +     RE+ LL+ L H N++ L  I  S  + +Y V EL   DL + +        PL    V+ +LYQ+L+G+ + HS  ++HRDLKP N+LIN    +K+ DFGLAR   +     T  V T +YRAPEI+L  + Y   VD+WS GCIFAEM+  + LFPG   + Q   I   LG+P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>153.68</Hsp_bit-score>
      <Hsp_score>387</Hsp_score>
      <Hsp_evalue>9.65095e-41</Hsp_evalue>
      <Hsp_query-from>285</Hsp_query-from>
      <Hsp_query-to>1154</Hsp_query-to>
      <Hsp_hit-from>23</Hsp_hit-from>
      <Hsp_hit-to>326</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>110</Hsp_identity>
      <Hsp_positive>160</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>308</Hsp_align-len>
      <Hsp_qseq>FQKVEKIGEGTYGVVYKARNKLTGE--AVALKKIRLDTETEGVPSTAIREISLLREL-NHPNIVRL--LTIIH----SEKKLYLVFELLDQDLKKFMDNATPSGIPL--PLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFG---VPQRTY-THEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGT-PDEVVWP-GVSQLPDYKSTFPRWANQELTKVVPTLNFEGRDLLAPTV-WVLHYLNTCDASCESRVLGLYVNKAD</Hsp_qseq>
      <Hsp_hseq>FQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIK----SGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPYLSIWHDPAD</Hsp_hseq>
      <Hsp_midline>FQ +++IG G YG+V  AR     E   VA+KK+        +   ++RE+ LLR    H NI  L  + I+     S   LYL  EL++ D+ + +     SG PL     +S+ YQ+L G+ + HS  +LHRDLKP NLL+NA+  +K+ DFGLAR +    V    + T  V T WYRAPEI+L  + Y+ ++DVWS GCI AE L  + +F G   ++QL +I + LGT PDE +   G   + DY              + P  N +  DLL   + +      T D + E   L ++ + AD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>148.673</Hsp_bit-score>
      <Hsp_score>374</Hsp_score>
      <Hsp_evalue>1.15608e-39</Hsp_evalue>
      <Hsp_query-from>285</Hsp_query-from>
      <Hsp_query-to>947</Hsp_query-to>
      <Hsp_hit-from>38</Hsp_hit-from>
      <Hsp_hit-to>271</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>89</Hsp_identity>
      <Hsp_positive>130</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>236</Hsp_align-len>
      <Hsp_qseq>FQKVEKIGEGTYGVV--YKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELN-HPNIVRL--LTIIHSE--KKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAF--------GVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDE</Hsp_qseq>
      <Hsp_hseq>YEIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGHKNIVNLIDLEIVTSSPYDGLYCYQELIDYDLAKVIHSSV--QLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDK</Hsp_hseq>
      <Hsp_midline>++ ++ +G+G YG V   K + +     +A+KKI      E +   AIRE+  +     H NIV L  L I+ S     LY   EL+D DL K + ++    +    +K +LYQ+L G+ + HS  ++HRDLKP N+L    G +K+ DFGLAR             Q   T+ V T WYRAPE+LL  + YS SVD+W++GCI AE   R+ +F G   + Q+F I + LGTPD+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>142.51</Hsp_bit-score>
      <Hsp_score>358</Hsp_score>
      <Hsp_evalue>1.18614e-37</Hsp_evalue>
      <Hsp_query-from>282</Hsp_query-from>
      <Hsp_query-to>1067</Hsp_query-to>
      <Hsp_hit-from>38</Hsp_hit-from>
      <Hsp_hit-to>300</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>87</Hsp_identity>
      <Hsp_positive>149</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>272</Hsp_align-len>
      <Hsp_qseq>NFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIH---SEKKLYL--VFELLDQDLKKFMDNATPSGIPLPL--VKSYLYQLLQGIAFCHSH-RILHRDLKPQNLLINAEG-AIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVSQLPDY-KSTFPRWANQELTKVVPTLNFEGRDLLA</Hsp_qseq>
      <Hsp_hseq>SFPTTEVVGHGSFGVVFATVIQETNEKVAIKKVLQDKRFKN------RELEIMKMLSHINIIDLKYFFYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLK-PTEPNVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILGTPSK--QEICSMNPNYMEHKFPQIKPIPLSRVFKKEDDQTVEFLA</Hsp_hseq>
      <Hsp_midline>+F   E +G G++GVV+    + T E VA+KK+  D   +       RE+ +++ L+H NI+ L    +   S+ ++YL  + E + Q L + + +      P+    +K Y++QL + + + H    + HRD+KPQNLL++ E  ++KL DFG A+    P       + + +YRAPE++ G  +Y+  +D+WS GC+ AE+L  + +FPG+S IDQL  I + LGTP +      S  P+Y +  FP+     L++V    + +  + LA</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>140.584</Hsp_bit-score>
      <Hsp_score>353</Hsp_score>
      <Hsp_evalue>1.73533e-35</Hsp_evalue>
      <Hsp_query-from>264</Hsp_query-from>
      <Hsp_query-to>941</Hsp_query-to>
      <Hsp_hit-from>31</Hsp_hit-from>
      <Hsp_hit-to>304</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>91</Hsp_identity>
      <Hsp_positive>143</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>275</Hsp_align-len>
      <Hsp_qseq>LRAAMDNFQKVEKIGEGTYGVVYKAR-----NKLTGEAVALKKIRLD----------TETEGVPS--------------TAIREISLLREL-NHPNIVRLLTI-IHSEK-KLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEG-----------------AIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTP</Hsp_qseq>
      <Hsp_hseq>LKTLSDRYQLIEKLGAGSFGCVTLAKAQFPLSNILGKQHDIRGTLMDQPKNGHQNYITKTQGVVAIKTMMTKLHTLQDYTRVREIKFILAIPANDHLIQIFEVFIDSENYQLHIVMECMEQNLYQMMKHRRRRVFSIPSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVEN-KNPYTAYVSTRWYRSPEILLRSGYYSKPLDIWAFGCVAVEVTVFRALFPGANEIDQIWKILEVLGTP</Hsp_hseq>
      <Hsp_midline>L+   D +Q +EK+G G++G V  A+     + + G+   ++   +D          T+T+GV +              T +REI  +  +  + +++++  + I SE  +L++V E ++Q+L + M +       +P +KS L Q+L G+   H H   HRDLKP+N+LI                      IKLADFGLAR     +  YT  V T WYR+PEILL   +YS  +D+W+ GC+  E+   RALFPG +EIDQ+++I   LGTP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YDL079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:312951:314748:-1 gene:YDL079C transcript:YDL079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRK1 description:Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication [Source:SGD;Acc:S000002237]</Hit_def>
  <Hit_accession>YDL079C</Hit_accession>
  <Hit_len>501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>134.42</Hsp_bit-score>
      <Hsp_score>337</Hsp_score>
      <Hsp_evalue>6.27225e-34</Hsp_evalue>
      <Hsp_query-from>297</Hsp_query-from>
      <Hsp_query-to>1076</Hsp_query-to>
      <Hsp_hit-from>168</Hsp_hit-from>
      <Hsp_hit-to>428</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>88</Hsp_identity>
      <Hsp_positive>141</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>270</Hsp_align-len>
      <Hsp_qseq>EKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKK-----LYLVFELLDQDLKKFMDNATPSGIPLPLV--KSYLYQLLQGIAFCHS-HRILHRDLKPQNLLINAEG-AIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVSQLPDYKS-TFPRWANQELTKVVPTLNFEGRDLLAPTV</Hsp_qseq>
      <Hsp_hseq>EVVGHGSFGVVVTTVIIETNQKVAIKKVLQDRRYKN------RELETMKMLCHPNTVGLQYYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLK-PDQPNVSYICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKIMGIPTKDEISGMN--PNYEDHVFPNIKPITLAEIFKAEDPDTLDLLTKTL</Hsp_hseq>
      <Hsp_midline>E +G G++GVV       T + VA+KK+  D   +       RE+  ++ L HPN V L    + + +     L LV + + Q L + + +     + +P V  K Y YQL + + + H+  RI HRD+KPQNLL++    + K+ DFG A+    P +     + + +YRAPE++ G  +YS  VDVWS  C+ AE+L  + LF G+S IDQL  I + +G P +    G++  P+Y+   FP      L ++    + +  DLL  T+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>132.494</Hsp_bit-score>
      <Hsp_score>332</Hsp_score>
      <Hsp_evalue>8.80655e-34</Hsp_evalue>
      <Hsp_query-from>282</Hsp_query-from>
      <Hsp_query-to>1064</Hsp_query-to>
      <Hsp_hit-from>22</Hsp_hit-from>
      <Hsp_hit-to>295</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>87</Hsp_identity>
      <Hsp_positive>146</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>278</Hsp_align-len>
      <Hsp_qseq>NFQKVEKIGEGTYGVV----YKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLREL-NHPNIVRLL---TIIHSEKKL---YLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRT----YTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVS--QLPDYKSTFPRWANQELTKVVPTLNFEGRDLL</Hsp_qseq>
      <Hsp_hseq>HFHLTGKIGRGSHSLICSSTYTESNEET--HVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLYEELMECDLSQII--RSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIPGRSFESILPGANPEALELL</Hsp_hseq>
      <Hsp_midline>+F    KIG G++ ++    Y   N+ T   VA++KI      +      +RE+ LLR L  HPNIV L     + +    L   YL  EL++ DL + +   +   +     +S++YQ+L  + + HS  +LH DLKP+NLL+N++  +K+ +FGL+ ++    +         + ++WY+APEILL  +  + +VD+WS GCI AE+L R+ +F G   +D L  I + LGTP E     ++  ++ +Y   F     +    ++P  N E  +LL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>130.954</Hsp_bit-score>
      <Hsp_score>328</Hsp_score>
      <Hsp_evalue>1.20722e-33</Hsp_evalue>
      <Hsp_query-from>288</Hsp_query-from>
      <Hsp_query-to>947</Hsp_query-to>
      <Hsp_hit-from>36</Hsp_hit-from>
      <Hsp_hit-to>261</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>132</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>235</Hsp_align-len>
      <Hsp_qseq>QKVEKIGEGTYGVVYKARNKLTGE------AVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIH----SEKKLY--LVFELLDQDLKKFMDNATPSGIPLPL--VKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAE-GAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDE</Hsp_qseq>
      <Hsp_hseq>KEYRKIGRGAFGTVVQAY--LTQDKKNWLGPFAIKKVPAHTEYKS------RELQILRIADHPNIVKLQYFFTHLSPQDNKVYQHLAMECLPETLQIEINRYVTNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSISY-ICSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLREIAKLLGPPDK</Hsp_hseq>
      <Hsp_midline>++  KIG G +G V +A   LT +        A+KK+   TE +       RE+ +LR  +HPNIV+L          + K+Y  L  E L + L+  ++    + + +PL  ++ Y YQ+ +G+ + H   + HRD+KP N+L++ E G +K+ DFG A+     Q + ++ + + +YRAPE+++GC  Y+T +D+W +GC+  EML  +A+F G   + QL  I + LG PD+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>128.642</Hsp_bit-score>
      <Hsp_score>322</Hsp_score>
      <Hsp_evalue>2.8669e-31</Hsp_evalue>
      <Hsp_query-from>303</Hsp_query-from>
      <Hsp_query-to>941</Hsp_query-to>
      <Hsp_hit-from>375</Hsp_hit-from>
      <Hsp_hit-to>589</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>125</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>219</Hsp_align-len>
      <Hsp_qseq>IGEGTYGVVYKARNKLTGEAVALKKIRLDTE--TEGVPSTAIREI--SLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINA--EGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTP</Hsp_qseq>
      <Hsp_hseq>LGQGTFGQVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKNHLCLVFELLSNNLYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPELKIIDFGSSCEEA---RTVYTYIQSRFYRAPEIILGIP-YSTSIDMWSLGCIVAELFLGIPIFPGASEYNQLTRIIDTLGYP</Hsp_hseq>
      <Hsp_midline>+G+GT+G V K +N LT E +A+K ++  TE  T+ +    I E+    +   N  + +R+      +  L LVFELL  +L + +      G+ + L++++  Q+L  +      +++H DLKP+N+L+ A  +  +K+ DFG +       RT    + + +YRAPEI+LG   YSTS+D+WS+GCI AE+     +FPG SE +QL RI  TLG P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>122.479</Hsp_bit-score>
      <Hsp_score>306</Hsp_score>
      <Hsp_evalue>1.5536e-29</Hsp_evalue>
      <Hsp_query-from>270</Hsp_query-from>
      <Hsp_query-to>974</Hsp_query-to>
      <Hsp_hit-from>50</Hsp_hit-from>
      <Hsp_hit-to>282</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>81</Hsp_identity>
      <Hsp_positive>128</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>240</Hsp_align-len>
      <Hsp_qseq>AAMDNFQKVEKIGEGTYGVVYKARNKLTGEAVALK----KIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFR-IFRTLGTPDEVVWPGVSQL</Hsp_qseq>
      <Hsp_hseq>AHIGNYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQG---RIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGNELFDYI--VQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFLKT-SCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPF-DDESIPVLFKNISNGVYTLPKFLSPGAAGL</Hsp_hseq>
      <Hsp_midline>A + N+Q V+ +GEG++G V  A +  TG+ VALK    K+   ++ +G      REIS LR L HP+I++L  +I S+ ++ +V E    +L  ++       +     + +  Q++  + +CH H+I+HRDLKP+NLL++    +K+ADFGL+          T    +  Y APE++ G  +    VDVWS G I   ML RR  F  D  I  LF+ I   + T  + + PG + L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>120.168</Hsp_bit-score>
      <Hsp_score>300</Hsp_score>
      <Hsp_evalue>2.08639e-28</Hsp_evalue>
      <Hsp_query-from>291</Hsp_query-from>
      <Hsp_query-to>1061</Hsp_query-to>
      <Hsp_hit-from>1177</Hsp_hit-from>
      <Hsp_hit-to>1453</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>87</Hsp_identity>
      <Hsp_positive>151</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>287</Hsp_align-len>
      <Hsp_qseq>KVEKIGEGTYGVVYKARNKLTGEAVALKKI---RLDTETEGVPST--AIR-EISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPL------PLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTL----WYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTP--DEVVWPGVSQL------------PDYKSTFPRWANQELTKVVPTLNFEGRDL</Hsp_qseq>
      <Hsp_hseq>KGEMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGF-ENKNNIYSLF------LEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRK---SKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANELLSHPFSEVNETFNFKSTRL</Hsp_hseq>
      <Hsp_midline>K E IG+G++G VY   N  TGE +A+K++   +  ++ E + ST  A+R E+S L++L+H NIV+ L    ++  +Y +F      L+     +  S I +      PL+K    Q+L+G+A+ HS  ILHRD+K  NLL++ +G  K++DFG++R     +  Y++  +T+    ++ APE++   + YS  VD+WS+GCI  EM   +  +     +  +F+I ++   P   E   P +SQ+            P+ + T     +   ++V  T NF+   L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>119.783</Hsp_bit-score>
      <Hsp_score>299</Hsp_score>
      <Hsp_evalue>2.26099e-28</Hsp_evalue>
      <Hsp_query-from>303</Hsp_query-from>
      <Hsp_query-to>875</Hsp_query-to>
      <Hsp_hit-from>31</Hsp_hit-from>
      <Hsp_hit-to>215</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>191</Hsp_align-len>
      <Hsp_qseq>IGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRR</Hsp_qseq>
      <Hsp_hseq>IGRGSYGVVYKAINKHTDQVVAIKEVVYENDEEL--NDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSALTLAG---TLNWMAPEI-LGNRGASTLSDIWSLGATVVEMLTKN</Hsp_hseq>
      <Hsp_midline>IG G+YGVVYKA NK T + VA+K++  + + E   +  + EISLL+ LNH NIV+    I    +LY++ E       + + + + +G+     K+Y+ Q L G+ + H   ++HRD+K  N+L++A+  +KLADFG++        T      TL + APEI LG +  ST  D+WS+G    EMLT+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YOR061W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:441534:442553:1 gene:YOR061W transcript:YOR061W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA2 description:Alpha&apos; catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000005587]</Hit_def>
  <Hit_accession>YOR061W</Hit_accession>
  <Hit_len>339</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>111.694</Hsp_bit-score>
      <Hsp_score>278</Hsp_score>
      <Hsp_evalue>2.19382e-27</Hsp_evalue>
      <Hsp_query-from>270</Hsp_query-from>
      <Hsp_query-to>938</Hsp_query-to>
      <Hsp_hit-from>45</Hsp_hit-from>
      <Hsp_hit-to>262</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>118</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>229</Hsp_align-len>
      <Hsp_qseq>AAMDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAI-REISLLRELNH-PNIVRLLTIIHS--EKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLIN-AEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRR-ALFPGDSEIDQLFRIFRTLGT</Hsp_qseq>
      <Hsp_hseq>GKISNYEIINKIGRGKYSEVFSGRCIVNNQKCVIKVLK------PVKMKKIYRELKILTNLTGGPNVVGLYDIVQDADSKIPALIFE----EIKNVDFRTLYPTFKLPDIQYYFTQLLIALDYCHSMGIMHRDVKPQNVMIDPTERKLRLIDWGLAE-FYHPGVDYNVRVASRYHKGPELLVNLNQYDYSLDLWSVGCMLAAIVFKKEPFFKGSSNPDQLVKIATVLGT</Hsp_hseq>
      <Hsp_midline>  + N++ + KIG G Y  V+  R  +  +   +K ++       V    I RE+ +L  L   PN+V L  I+     K   L+FE    ++K            LP ++ Y  QLL  + +CHS  I+HRD+KPQN++I+  E  ++L D+GLA  F  P   Y   V + +++ PE+L+    Y  S+D+WS+GC+ A ++ ++   F G S  DQL +I   LGT</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>109.768</Hsp_bit-score>
      <Hsp_score>273</Hsp_score>
      <Hsp_evalue>1.80905e-26</Hsp_evalue>
      <Hsp_query-from>297</Hsp_query-from>
      <Hsp_query-to>935</Hsp_query-to>
      <Hsp_hit-from>45</Hsp_hit-from>
      <Hsp_hit-to>266</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>119</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>233</Hsp_align-len>
      <Hsp_qseq>EKIGEGTYGVVYKARNKLTGEAV------ALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHS-----------EKKLYLVF--ELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLI-NAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLG</Hsp_qseq>
      <Hsp_hseq>KRIGHGSFGTV--TQSILSSNSIEWLGPYAIKRVV------KSPKVQSLELEILQNIRHPNLVTLEFFFESHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNG--SKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGIAKVCDFGSAQRLDDNTELKTY-FCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPLFKGDSANSQLEEIAKLLG</Hsp_hseq>
      <Hsp_midline>++IG G++G V   ++ L+  ++      A+K++         P     E+ +L+ + HPN+V L     S           +K   + +  + L  ++ ++ DN   S +P   +K Y +Q+L+ +   HS  I H DLKP N+LI  + G  K+ DFG A+         T+   + +YRAPE+LL  K Y+T +D+WS+GCI  EM+  + LF GDS   QL  I + LG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>108.227</Hsp_bit-score>
      <Hsp_score>269</Hsp_score>
      <Hsp_evalue>1.07834e-24</Hsp_evalue>
      <Hsp_query-from>297</Hsp_query-from>
      <Hsp_query-to>899</Hsp_query-to>
      <Hsp_hit-from>23</Hsp_hit-from>
      <Hsp_hit-to>234</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>218</Hsp_align-len>
      <Hsp_qseq>EKIGEGTYGVVYKARNKLTGEAVALKKIRL---------------DTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKS--YLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSE</Hsp_qseq>
      <Hsp_hseq>ETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAE---KGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMA-ALETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGR--LPFDEE</Hsp_hseq>
      <Hsp_midline>E +G G+ G V  ARN  TG+  A+K I                  T  + +P    REI +++ LNHPN++RL  +  +   LYLV E  +   K  + N      PLP  ++  +  Q++ G+++CH+  I+HRDLKP+NLL++ +  IK+ADFG+A A     +       +  Y APEI+ G  +   + DVWS G I   +LT R   P D E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>108.227</Hsp_bit-score>
      <Hsp_score>269</Hsp_score>
      <Hsp_evalue>1.10157e-24</Hsp_evalue>
      <Hsp_query-from>288</Hsp_query-from>
      <Hsp_query-to>875</Hsp_query-to>
      <Hsp_hit-from>1035</Hsp_hit-from>
      <Hsp_hit-to>1249</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>217</Hsp_align-len>
      <Hsp_qseq>QKVEKIGEGTYGVVYKARNKLTGEAVALKKIRL-DTETEGVPSTAIRE-ISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQ-DLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARA----------------FGVPQRTYTHEVVTLWYRAPEILLG--CKHYSTSVDVWSIGCIFAEMLTRR</Hsp_qseq>
      <Hsp_hseq>QKRSFIGGGTFGQVYSAINLENGEILAVKEIKIHDTTTMKKIFPLIKEEMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEYCEGGSLASLLDHGRIEDEMVTQV--YTFELLEGLAYLHQSGVVHRDIKPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGR</Hsp_hseq>
      <Hsp_midline>QK   IG GT+G VY A N   GE +A+K+I++ DT T       I+E +++L  LNHPNIV+   +     K+ +  E  +   L   +D+       +  V  Y ++LL+G+A+ H   ++HRD+KP+N+L++  G IK  DFG AR                 FGV  ++    + T  Y APE + G   K    + DVW++GC+  EM T R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YIL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:287790:288908:-1 gene:YIL035C transcript:YIL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA1 description:Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000001297]</Hit_def>
  <Hit_accession>YIL035C</Hit_accession>
  <Hit_len>372</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>103.219</Hsp_bit-score>
      <Hsp_score>256</Hsp_score>
      <Hsp_evalue>3.49352e-24</Hsp_evalue>
      <Hsp_query-from>453</Hsp_query-from>
      <Hsp_query-to>1001</Hsp_query-to>
      <Hsp_hit-from>130</Hsp_hit-from>
      <Hsp_hit-to>306</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>188</Hsp_align-len>
      <Hsp_qseq>HPNIVRLLTIIHS--EKKLYLVFELLDQ-DLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEG-AIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRA-LFPGDSEIDQLFRIFRTLGTPDEVVWPGVSQLPDYKSTFPR</Hsp_qseq>
      <Hsp_hseq>HANIIHLFDIIKDPISKTPALVFEYVDNVDFRILYPKLTDLEI-----RFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHV-NMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSD-----FEKYLLKYEITLPR</Hsp_hseq>
      <Hsp_midline>H NI+ L  II     K   LVFE +D  D +      T   I     + Y+++LL+ + +CHS  I+HRD+KP N++I+ +   ++L D+GLA  + V    Y   V + +++ PE+L+  + Y  S+D+WS G + A M+ +R   F G S  DQL +I + LGT D         L  Y+ T PR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>105.916</Hsp_bit-score>
      <Hsp_score>263</Hsp_score>
      <Hsp_evalue>4.37199e-24</Hsp_evalue>
      <Hsp_query-from>297</Hsp_query-from>
      <Hsp_query-to>917</Hsp_query-to>
      <Hsp_hit-from>202</Hsp_hit-from>
      <Hsp_hit-to>418</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>222</Hsp_align-len>
      <Hsp_qseq>EKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQ-DLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGA--IKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGC------------KHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFR</Hsp_qseq>
      <Hsp_hseq>EVVGQGAFATVKKAIERTTGKTFAVKIIS-KRKVIGNMDGVTRELEVLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFV--AAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMKTF-CGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQ-DQLYK</Hsp_hseq>
      <Hsp_midline>E +G+G +  V KA  + TG+  A+K I    +  G      RE+ +L++LNHP IVRL       +  Y+V E +   DL  F+  A    +     +    Q+L  I + HS  I HRDLKP N+LI  +    +K+ DFGLA+  G      T    TL Y APE++ G               YS+ VD+WS+GC+   +LT    F G ++ DQL++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>96.2857</Hsp_bit-score>
      <Hsp_score>238</Hsp_score>
      <Hsp_evalue>7.71645e-22</Hsp_evalue>
      <Hsp_query-from>267</Hsp_query-from>
      <Hsp_query-to>884</Hsp_query-to>
      <Hsp_hit-from>82</Hsp_hit-from>
      <Hsp_hit-to>283</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>209</Hsp_align-len>
      <Hsp_qseq>RAAMDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDT--ETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQ-DLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALF</Hsp_qseq>
      <Hsp_hseq>KYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTN-DERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKS--QRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKY--VPDVTYTL-CGTPDYIAPEV-VSTKPYNKSVDWWSFGVLIYEMLAGYTPF</Hsp_hseq>
      <Hsp_midline>+ ++ +FQ +  +G G++G V+  R+   G   ALK ++  T  + + V  T   E  +L  ++HP I+R+       +++++V + ++  +L   +  +     P P+ K Y  ++   + + HS  I++RDLKP+N+L++  G IK+ DFG A+   VP  TYT    T  Y APE+ +  K Y+ SVD WS G +  EML     F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>98.2117</Hsp_bit-score>
      <Hsp_score>243</Hsp_score>
      <Hsp_evalue>1.16715e-21</Hsp_evalue>
      <Hsp_query-from>297</Hsp_query-from>
      <Hsp_query-to>899</Hsp_query-to>
      <Hsp_hit-from>25</Hsp_hit-from>
      <Hsp_hit-to>230</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>212</Hsp_align-len>
      <Hsp_qseq>EKIGEGTYGVVYKARNKLTGEAVALKKI---------RLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSY--LYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSE</Hsp_qseq>
      <Hsp_hseq>ETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAE---KGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMA-ALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGR--LPFDEE</Hsp_hseq>
      <Hsp_midline>E +G G+ G V  A+++ TG   A+K I             +   +P    REI +++ L+HPN++ L  +  +   LYL+ E  +   K  + N      PLP  ++     Q++ GI++CH+  I+HRDLKP+NLL+++   IK+ADFG+A A             +  Y APEI+ G  +   + DVWS G I   +LT R   P D E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>96.2857</Hsp_bit-score>
      <Hsp_score>238</Hsp_score>
      <Hsp_evalue>1.88314e-21</Hsp_evalue>
      <Hsp_query-from>297</Hsp_query-from>
      <Hsp_query-to>854</Hsp_query-to>
      <Hsp_hit-from>204</Hsp_hit-from>
      <Hsp_hit-to>411</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>211</Hsp_align-len>
      <Hsp_qseq>EKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIRE-ISLLRELNHPNIVRLLT-----IIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLIN-------------------AEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIF</Hsp_qseq>
      <Hsp_hseq>KELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKID-DGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTL-CGTPSYVAPEVLTK-KGYTSKVDLWSAGVIL</Hsp_hseq>
      <Hsp_midline>+++G G Y +V +A+NK TG+ VA+K        +   +   RE  ++L  + HPNIV LL      I  S+ + YLV E +D D + F      + +     K+   QLL G+ + H   I+HRD+KP+N+L+N                    +  +K+ADFGLA+  G  Q T T    T  Y APE+L   K Y++ VD+WS G I </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>97.0561</Hsp_bit-score>
      <Hsp_score>240</Hsp_score>
      <Hsp_evalue>2.36857e-21</Hsp_evalue>
      <Hsp_query-from>303</Hsp_query-from>
      <Hsp_query-to>956</Hsp_query-to>
      <Hsp_hit-from>421</Hsp_hit-from>
      <Hsp_hit-to>680</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>120</Hsp_positive>
      <Hsp_gaps>54</Hsp_gaps>
      <Hsp_align-len>266</Hsp_align-len>
      <Hsp_qseq>IGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIR------------------------------------------EISLLRELNHPNIVRLLTIIHSEKKLYLVFELL-DQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVV---TLWYRAPEILLGCKHYSTS--VDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDEVVW</Hsp_qseq>
      <Hsp_hseq>IGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGP--FEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVV---KQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKI-GTNTTPEIPSW</Hsp_hseq>
      <Hsp_midline>IG G++G VY   N  TGE +A+K++ +     GVP+   +                                          E++LL+EL+H NIV           L +  E +    +   ++N  P      L+ ++  Q+L G+A+ H   I+HRD+K  N+LI+ +G +K+ DFG+++      +          ++++ +PE++   K  +T+   D+WS GC+  EM T +  FP  S++  +F+I  T  TP+   W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>94.3597</Hsp_bit-score>
      <Hsp_score>233</Hsp_score>
      <Hsp_evalue>2.67041e-21</Hsp_evalue>
      <Hsp_query-from>267</Hsp_query-from>
      <Hsp_query-to>1067</Hsp_query-to>
      <Hsp_hit-from>64</Hsp_hit-from>
      <Hsp_hit-to>320</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>270</Hsp_align-len>
      <Hsp_qseq>RAAMDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLD--TETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQ-DLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVSQLPDYKSTFPRWANQELTKVVPTLNFEGRDLLA</Hsp_qseq>
      <Hsp_hseq>KYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTN-DERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKS--QRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKE--VQTVTWT-LCGTPDYIAPEVIT-TKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQ-----GKVVYPPYFH-PDVVDLLSKLITADLTRRIGNLQSGSRDIKA</Hsp_hseq>
      <Hsp_midline>+  + +FQ +  +G G++G V+  R+   G   A+K ++     + + V  T   E  +L+ + HP ++R+       + +++V + ++  +L   +  +     P P+ K Y  +++  + + H+H I++RDLKP+N+L++  G IK+ DFG A+   V   T+T    T  Y APE++   K Y+ SVD WS+G +  EML     F   + +    +I +      +VV+P     PD      +    +LT+ +  L    RD+ A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>94.3597</Hsp_bit-score>
      <Hsp_score>233</Hsp_score>
      <Hsp_evalue>2.704e-21</Hsp_evalue>
      <Hsp_query-from>273</Hsp_query-from>
      <Hsp_query-to>869</Hsp_query-to>
      <Hsp_hit-from>100</Hsp_hit-from>
      <Hsp_hit-to>296</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>202</Hsp_align-len>
      <Hsp_qseq>AMDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETE-GVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFE-LLDQDLKKFMDNATP-SGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLT</Hsp_qseq>
      <Hsp_hseq>SLDDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDI---LASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWS-IINPPENRRKTVCGTIDYLSPE-MVESREYDHTIDAWALGVLAFELLT</Hsp_hseq>
      <Hsp_midline>++D+F+  +K+G+G +G VY  R++ TG   ALK +  +   +  +     RE+ +   LNHPN+ +     H EK++YL+ E L++ ++ K +    P + I   L   Y+YQ+   + + H   I+HRD+KP+N+LI     IKL DFG +     P+        T+ Y +PE ++  + Y  ++D W++G +  E+LT</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>97.4413</Hsp_bit-score>
      <Hsp_score>241</Hsp_score>
      <Hsp_evalue>3.05909e-21</Hsp_evalue>
      <Hsp_query-from>297</Hsp_query-from>
      <Hsp_query-to>920</Hsp_query-to>
      <Hsp_hit-from>85</Hsp_hit-from>
      <Hsp_hit-to>327</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>246</Hsp_align-len>
      <Hsp_qseq>EKIGEGTYGVVYKARNKLTGEAVALKKI---------------------RLDTETEGVPSTAI---------------REISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSG-IPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEG-AIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRI</Hsp_qseq>
      <Hsp_hseq>KTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGG--ELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMA-ALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKV</Hsp_hseq>
      <Hsp_midline>+ +G+G+ G V  A+N  TG+  A+K +                      + T     PS A                REI +++ ++H N++ L  +  ++ +LYLV E +D    +  D     G +P      Y  Q+++G+++CHS  I HRDLKP+NLL++ +   IK+ADFG+A A  +P +       +  Y +PEI++G  ++    DVWS G +   +LT    F  D+    L ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>94.3597</Hsp_bit-score>
      <Hsp_score>233</Hsp_score>
      <Hsp_evalue>4.95342e-21</Hsp_evalue>
      <Hsp_query-from>303</Hsp_query-from>
      <Hsp_query-to>884</Hsp_query-to>
      <Hsp_hit-from>43</Hsp_hit-from>
      <Hsp_hit-to>239</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>207</Hsp_align-len>
      <Hsp_qseq>IGEGTYGVVYKARNKLTGEAVALK-KIRLDTETEGVPSTAI-REISLLRELNHPNIVRLLTIIHSEKKLYLVF------ELLDQDLKK--FMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLI---NAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALF</Hsp_qseq>
      <Hsp_hseq>LGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVR---------ILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGH-GKPCDIWSIGVITYTLLCGYSAF</Hsp_hseq>
      <Hsp_midline>+G GT+GVV +A+N  TGE VA+K  I+   +   V   A+  E+ +L+ L+HPNIV       S+ K Y++       EL D+ LKK  F +               L ++L  + + HS  I+HRDLKP+NLL    + E  + +ADFG+A+     +        +L Y APE+L    H     D+WSIG I   +L   + F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>92.8189</Hsp_bit-score>
      <Hsp_score>229</Hsp_score>
      <Hsp_evalue>1.14439e-20</Hsp_evalue>
      <Hsp_query-from>267</Hsp_query-from>
      <Hsp_query-to>866</Hsp_query-to>
      <Hsp_hit-from>81</Hsp_hit-from>
      <Hsp_hit-to>276</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>203</Hsp_align-len>
      <Hsp_qseq>RAAMDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLD--TETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQ-DLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEML</Hsp_qseq>
      <Hsp_hseq>KYSLQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERL-MLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKS--QRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKY--VPDVTYTL-CGTPDYIAPEV-VSTKPYNKSIDWWSFGILIYEML</Hsp_hseq>
      <Hsp_midline>+ ++ +FQ +  +G G++G V+  R++  G   A+K ++ +     + V  T    + +L  + HP I+R+       ++++++ + ++  +L   +  +     P P+ K Y  ++   + + HS  I++RDLKP+N+L++  G IK+ DFG A+   VP  TYT    T  Y APE+ +  K Y+ S+D WS G +  EML</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.1301</Hsp_bit-score>
      <Hsp_score>235</Hsp_score>
      <Hsp_evalue>1.31235e-20</Hsp_evalue>
      <Hsp_query-from>285</Hsp_query-from>
      <Hsp_query-to>869</Hsp_query-to>
      <Hsp_hit-from>23</Hsp_hit-from>
      <Hsp_hit-to>215</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>197</Hsp_align-len>
      <Hsp_qseq>FQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNH-PNIVRLLTIIHSEKKLYLVFE-LLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLT</Hsp_qseq>
      <Hsp_hseq>FKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQ-REIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLL---RPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIAT</Hsp_hseq>
      <Hsp_midline>F++ E IG G +GVVYK  N  TG   A+K + LD++++ V     REI  L  L    NI R       +  L+++ E      L+  +    P  I    +   + +LL  +   H   ++HRD+K  N+LI  EG +KL DFG+A               T ++ APE+++   +Y T VD+WS+G    E+ T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.5893</Hsp_bit-score>
      <Hsp_score>231</Hsp_score>
      <Hsp_evalue>1.84162e-20</Hsp_evalue>
      <Hsp_query-from>267</Hsp_query-from>
      <Hsp_query-to>905</Hsp_query-to>
      <Hsp_hit-from>44</Hsp_hit-from>
      <Hsp_hit-to>283</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>119</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>244</Hsp_align-len>
      <Hsp_qseq>RAAMDNFQKVEKIGEGTYGVVYKARNKLTGEAVALK-----------KIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEK--KLYLVFELLDQ-------DLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLA--RAFGVPQRTYTHEVV-------TLWYRAPEILLGCKHYSTS--VDVWSIGCIFAEMLTRRALFPGDSEID</Hsp_qseq>
      <Hsp_hseq>RQILNNFEILATLGNGQYGKVKLARDLGTGALVAIKILNRFEKRSGYSLQLKVENPRVN----QEIEVMKRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPFNANSGLE</Hsp_hseq>
      <Hsp_midline>R  ++NF+ +  +G G YG V  AR+  TG  VA+K            ++L  E   V     +EI +++  +H N+V L  I++  +  K+YLV E   +       + K  +    PS +     +  +  ++ G+ + HS  I HRD+KP NLLI++ G +K++DFG+A   A G      +HE +       T  + APE+    K YS S  +D+WS+G     +L  +  F  +S ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.5893</Hsp_bit-score>
      <Hsp_score>231</Hsp_score>
      <Hsp_evalue>2.70028e-20</Hsp_evalue>
      <Hsp_query-from>285</Hsp_query-from>
      <Hsp_query-to>941</Hsp_query-to>
      <Hsp_hit-from>360</Hsp_hit-from>
      <Hsp_hit-to>600</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>120</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>245</Hsp_align-len>
      <Hsp_qseq>FQKVEKIGEGTYGVVYKAR-----------------NKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLL-TIIHSEKKLYLVFELLDQD-LKKFMDNATPSGI---PLPLVKSYLYQLL----QGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTP</Hsp_qseq>
      <Hsp_hseq>FQLVEKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQPKK--QLIMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEI-VNQKGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANN-GSP</Hsp_hseq>
      <Hsp_midline>FQ VEK G+G  G VY ++                 +++ GE VA+K+IRL  + +      + E+ ++ +    NIV  L   I  +++L+++ E ++   L   +D    S       PL ++ +  ++    QG+ F H+ +I+HRD+K  N+L+N++G +K+ DFG        +      V T ++ APEI +  K Y   VDVWS+G +  EM+     +  +  +  L+ I    G+P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>92.4337</Hsp_bit-score>
      <Hsp_score>228</Hsp_score>
      <Hsp_evalue>2.80757e-20</Hsp_evalue>
      <Hsp_query-from>303</Hsp_query-from>
      <Hsp_query-to>866</Hsp_query-to>
      <Hsp_hit-from>24</Hsp_hit-from>
      <Hsp_hit-to>211</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>191</Hsp_align-len>
      <Hsp_qseq>IGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQ-DLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCK--HYSTSVDVWSIGCIFAEML</Hsp_qseq>
      <Hsp_hseq>IGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLA-QEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRDTF-VGTPYWMAPEVVC-CEVDGYNEKADIWSLGITTYELL</Hsp_hseq>
      <Hsp_midline>IG G +G VYKA +++T E VA+K + L+   E +   A +EI  L EL  P I   +  +  +  +++V E          +  +  +G+P   V   ++++  G+ + H  R +HRD+K  N+L+N EG +KL DFG++       +  T  V T ++ APE++  C+   Y+   D+WS+G    E+L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.9745</Hsp_bit-score>
      <Hsp_score>232</Hsp_score>
      <Hsp_evalue>2.81226e-20</Hsp_evalue>
      <Hsp_query-from>300</Hsp_query-from>
      <Hsp_query-to>941</Hsp_query-to>
      <Hsp_hit-from>625</Hsp_hit-from>
      <Hsp_hit-to>832</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>214</Hsp_align-len>
      <Hsp_qseq>KIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTP</Hsp_qseq>
      <Hsp_hseq>KIGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKK--ELIINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGG--SLTDVVTHCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTMVGTPYWMAPEV-VSRKEYGPKVDIWSLGIMIIEMIEGEPPYLNETPLRALY-LIATNGTP</Hsp_hseq>
      <Hsp_midline>KIG+G  G VY A    T  +VA+K++ L+ + +      I EI +++   HPNIV  +     +  L+++ E ++       D  T   +    + +   + L G+ F HS  +LHRD+K  N+L++ EG IKL DFG            T  V T ++ APE+ +  K Y   VD+WS+G +  EM+     +  ++ +  L+ +  T GTP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>91.6633</Hsp_bit-score>
      <Hsp_score>226</Hsp_score>
      <Hsp_evalue>1.80592e-19</Hsp_evalue>
      <Hsp_query-from>288</Hsp_query-from>
      <Hsp_query-to>875</Hsp_query-to>
      <Hsp_hit-from>1267</Hsp_hit-from>
      <Hsp_hit-to>1497</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>233</Hsp_align-len>
      <Hsp_qseq>QKVEKIGEGTYGVVYKARNKLTGEAVALKKIRL-DTET-EGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQ-DLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFG-----------VPQRTYTHEVVTL---------------------WYRAPEILLGC--KHYSTSVDVWSIGCIFAEMLTRR</Hsp_qseq>
      <Hsp_hseq>QKRNFIGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAALLEHGRIEDEMVTQV--YTLQLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGR</Hsp_hseq>
      <Hsp_midline>QK   IG GT+G VY A +   GE +A+K+I + D+++ + +      E+S+L  LNHPNIV    +     K+ +  E  +   L   +++       +  V  Y  QLL+G+A+ H   I+HRD+KP+N+L++  G IK  DFG A+              +      HE VT                       Y APE + G   K    + DVWS+GC+  EM+T R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.1225</Hsp_bit-score>
      <Hsp_score>222</Hsp_score>
      <Hsp_evalue>2.79135e-19</Hsp_evalue>
      <Hsp_query-from>273</Hsp_query-from>
      <Hsp_query-to>869</Hsp_query-to>
      <Hsp_hit-from>340</Hsp_hit-from>
      <Hsp_hit-to>537</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>200</Hsp_align-len>
      <Hsp_qseq>AMDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPST-AIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLT</Hsp_qseq>
      <Hsp_hseq>SIDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGG-ELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLG-QGYTKTVDWWTLGILLYEMMT</Hsp_hseq>
      <Hsp_midline>++D+F  ++ IG+G++G V + R K T +  ALK +R          T  + E ++L  ++ P IV L     S +KLYLV   ++   + F          L   + Y+ +LL  +   H   +++RDLKP+N+L++ +G I L DFGL +              T  Y APEILLG + Y+ +VD W++G +  EM+T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.1225</Hsp_bit-score>
      <Hsp_score>222</Hsp_score>
      <Hsp_evalue>2.92062e-19</Hsp_evalue>
      <Hsp_query-from>282</Hsp_query-from>
      <Hsp_query-to>998</Hsp_query-to>
      <Hsp_hit-from>81</Hsp_hit-from>
      <Hsp_hit-to>342</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>128</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>267</Hsp_align-len>
      <Hsp_qseq>NFQKVEKIGEGTYGVVYKARNKLTGEAVALKKI-RLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELL-DQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFG-VPQRTYTHEVVTLWYRAPEILLGCKH--YSTSVDVWSIGCIFAEMLT-------------------RRALFPGDSEIDQLFRIF-RTLGTPDEVVWPGVSQLPDY---KSTFP</Hsp_qseq>
      <Hsp_hseq>DYHRGHFLGEGGFARCFQIKDD-SGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRR--KVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYT-ICGTPNYIAPEVLMG-KHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRDKPISDEGKILIRDILSLDPIERPSLTEIMDYVWFRGTFP</Hsp_hseq>
      <Hsp_midline>++ +   +GEG +   ++ ++  +GE  A K + +   ++E      + EI + + ++HPNIV+ +     +  +Y++ E+  +  L + +       +  P V+ +  Q+   I + HS R++HRDLK  N+  ++   +K+ DFGLA       +R YT    T  Y APE+L+G KH  +S  VD+WS+G +   +L                    R   FP D  I    +I  R + + D +  P ++++ DY   + TFP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>89.7373</Hsp_bit-score>
      <Hsp_score>221</Hsp_score>
      <Hsp_evalue>5.93304e-19</Hsp_evalue>
      <Hsp_query-from>267</Hsp_query-from>
      <Hsp_query-to>959</Hsp_query-to>
      <Hsp_hit-from>818</Hsp_hit-from>
      <Hsp_hit-to>1044</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>125</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>239</Hsp_align-len>
      <Hsp_qseq>RAAMDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDT--ETEGVPST-AIREISLL-RELNHPNIVRLLTIIHSEKKLYLVFELLDQ-DLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARA---FGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDEVVWP</Hsp_qseq>
      <Hsp_hseq>KVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQR---LSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTF---CGTPEFMAPEILKE-QEYTKAVDWWAFGVLLYQMLLCQSPFSGDDE-DEVFNAILT----DEPLYP</Hsp_hseq>
      <Hsp_midline>+ ++DNF  ++ +G+G +G V  +++K T    A+K ++ D   +   + S  A +++ LL  +  HP +  L     +E ++Y   E +   DL   + N     + +   K Y  ++L  + + H + +++RDLK +N+L+  EG IK+AD+GL +    +G    T+     T  + APEIL   + Y+ +VD W+ G +  +ML  ++ F GD E D++F    T    DE ++P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>89.3521</Hsp_bit-score>
      <Hsp_score>220</Hsp_score>
      <Hsp_evalue>6.25029e-19</Hsp_evalue>
      <Hsp_query-from>273</Hsp_query-from>
      <Hsp_query-to>869</Hsp_query-to>
      <Hsp_hit-from>343</Hsp_hit-from>
      <Hsp_hit-to>540</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>202</Hsp_align-len>
      <Hsp_qseq>AMDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIR---LDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLT</Hsp_qseq>
      <Hsp_hseq>SIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAER--TVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGG-ELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLG-YTKAVDWWTLGVLLYEMLT</Hsp_hseq>
      <Hsp_midline>++D+F  ++ IG+G++G V + R K T +  ALK IR   + +++E   + A R  ++L  ++ P IV L     S +KLY V   ++   + F          L   + Y  +LL  +   H   +++RDLKP+N+L++ +G I L DFGL +              T  Y APE+LLG   Y+ +VD W++G +  EMLT</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.0409</Hsp_bit-score>
      <Hsp_score>214</Hsp_score>
      <Hsp_evalue>2.18546e-18</Hsp_evalue>
      <Hsp_query-from>264</Hsp_query-from>
      <Hsp_query-to>890</Hsp_query-to>
      <Hsp_hit-from>121</Hsp_hit-from>
      <Hsp_hit-to>364</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>246</Hsp_align-len>
      <Hsp_qseq>LRAAMDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIR----------LDTETEGVPST-----------------AIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHE----------VVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPG</Hsp_qseq>
      <Hsp_hseq>LSRNLHDFKPVRVLGQGAYGKVLLVKDVNTSKLYAMKQLRKAEILISQTATDSKREDEDKNDGNNNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGG-ELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLG-KAYSQNCDWYSLGCLLYDMLVGKPPYTG</Hsp_hseq>
      <Hsp_midline>L   + +F+ V  +G+G YG V   ++  T +  A+K++R           D++ E                         E S+L E+ HPNIV+L    H   KLYL+ + +    + F        +    V  Y  ++   + F H+  +++RDLKP+N L+N  G + L DFGL++           +          + T  Y APEILLG K YS + D +S+GC+  +ML  +  + G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.8853</Hsp_bit-score>
      <Hsp_score>211</Hsp_score>
      <Hsp_evalue>4.69659e-18</Hsp_evalue>
      <Hsp_query-from>303</Hsp_query-from>
      <Hsp_query-to>893</Hsp_query-to>
      <Hsp_hit-from>220</Hsp_hit-from>
      <Hsp_hit-to>418</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>204</Hsp_align-len>
      <Hsp_qseq>IGEGTYGVVYKARNKLTGEAVALKKIR-LDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKK--LYLVFELLD-QDLKKFMDNATPSG--IPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLA-RAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGD</Hsp_qseq>
      <Hsp_hseq>LGEGAGGSVAKCRLKNGKKVFALKTINTMNTDPE-YQKQIFRELQFNKSFKSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFGVSGEAVNSLAMTFTG---TSFYMAPERIQG-QPYSVTCDVWSLGLTLLEVAGGRFPFESD</Hsp_hseq>
      <Hsp_midline>+GEG  G V K R K   +  ALK I  ++T+ E       RE+   +      IV+   +   E+   +Y+  E +  + L+    N    G  I   ++      +L+G+++ H  +++HRD+KPQN+L+N +G IKL DFG++  A      T+T    T +Y APE + G + YS + DVWS+G    E+   R  F  D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.5001</Hsp_bit-score>
      <Hsp_score>210</Hsp_score>
      <Hsp_evalue>4.73648e-18</Hsp_evalue>
      <Hsp_query-from>303</Hsp_query-from>
      <Hsp_query-to>896</Hsp_query-to>
      <Hsp_hit-from>53</Hsp_hit-from>
      <Hsp_hit-to>253</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>205</Hsp_align-len>
      <Hsp_qseq>IGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVP---STAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPL-VKSYLYQLLQGIAFCHSHRILHRDLKPQNLLI---NAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDS</Hsp_qseq>
      <Hsp_hseq>LGAGSFGVVRQARKLSTNEDVAIK-ILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATG--GELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGH-GKPCDIWSIGVITYTLLCGYSPFIAES</Hsp_hseq>
      <Hsp_midline>+G G++GVV +AR   T E VA+K I L    +G          E+S+L++L+HPNIV       S+ K Y+V +L      +  D     G    +     + Q+L  + + HS  ++HRDLKP+N+L    +    + +ADFG+A+     +        +L Y APE+L    H     D+WSIG I   +L   + F  +S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YDL028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:400997:403291:-1 gene:YDL028C transcript:YDL028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MPS1 description:Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]</Hit_def>
  <Hit_accession>YDL028C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.2705</Hsp_bit-score>
      <Hsp_score>212</Hsp_score>
      <Hsp_evalue>5.77015e-18</Hsp_evalue>
      <Hsp_query-from>285</Hsp_query-from>
      <Hsp_query-to>866</Hsp_query-to>
      <Hsp_hit-from>440</Hsp_hit-from>
      <Hsp_hit-to>648</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>216</Hsp_align-len>
      <Hsp_qseq>FQKVEKIGEGTYGVVYKARNKLTGEAV-ALKKIRLDTETEGVPSTAIREISLLREL-NHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPL--VKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYT----HEVVTLWYRAPEILLGCKHYSTS--------------VDVWSIGCIFAEML</Hsp_qseq>
      <Hsp_hseq>YEKIELLGRGGSSRVYKV--KGSGNRVYALKRVSFDAFDDSSIDGFKGEIELLEKLKDQKRVIQLLDYEMGDGLLYLIMECGDHDLSQILNQR--SGMPLDFNFVRFYTKEMLLCIKVVHDAGIVHSDLKPANFVL-VKGILKIIDFGIANA--VPEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMI</Hsp_hseq>
      <Hsp_midline>++K+E +G G    VYK   K +G  V ALK++  D   +        EI LL +L +   +++LL     +  LYL+ E  D DL + ++    SG+PL    V+ Y  ++L  I   H   I+H DLKP N ++  +G +K+ DFG+A A  VP+ T       ++ T  Y APE L+   +   S               D+WS GCI  +M+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.2705</Hsp_bit-score>
      <Hsp_score>212</Hsp_score>
      <Hsp_evalue>6.61783e-18</Hsp_evalue>
      <Hsp_query-from>282</Hsp_query-from>
      <Hsp_query-to>959</Hsp_query-to>
      <Hsp_hit-from>40</Hsp_hit-from>
      <Hsp_hit-to>257</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>227</Hsp_align-len>
      <Hsp_qseq>NFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQG-IAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDEVVWP</Hsp_qseq>
      <Hsp_hseq>NYKILKQIGEGSFGKVYLALHRPTHRKVCLK-----TSDKNDPNI-VREVFYHRQFDFPYITKLYEVIVTESKVWMALEYCPG--KELYDHLLSLRRISLLECGELFAQISGAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTREC-MTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDAKVIP</Hsp_hseq>
      <Hsp_midline>N++ +++IGEG++G VY A ++ T   V LK     T  +  P+  +RE+   R+ + P I +L  +I +E K+++  E      K+  D+         L    L+  + G + + HS   +HRDLK +N+L++  G  KL DFG  R   + + T      T  Y APE++    +    +D+WS+G I   ++T    F  D E    ++I       D  V P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.2705</Hsp_bit-score>
      <Hsp_score>212</Hsp_score>
      <Hsp_evalue>7.00326e-18</Hsp_evalue>
      <Hsp_query-from>264</Hsp_query-from>
      <Hsp_query-to>899</Hsp_query-to>
      <Hsp_hit-from>172</Hsp_hit-from>
      <Hsp_hit-to>394</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>236</Hsp_align-len>
      <Hsp_qseq>LRAAMDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLD--TETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSY-----------LYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHE-----------VVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSE</Hsp_qseq>
      <Hsp_hseq>IKKGIKDFKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEY------------APNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPE-LLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNE</Hsp_hseq>
      <Hsp_midline>++  + +F+    IG+G Y  V  A +  T +  A K +  +     + V   +I + +L +  N P++VRL +    E  LY + E              P+G  L L+K Y             Q++  I + HS+ I+HRD+KP+N+L++ E  IKL DFG A+       + +             V T  Y +PE LL         D+W+ GCI  +M+  +  F   +E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.8853</Hsp_bit-score>
      <Hsp_score>211</Hsp_score>
      <Hsp_evalue>7.77543e-18</Hsp_evalue>
      <Hsp_query-from>264</Hsp_query-from>
      <Hsp_query-to>1016</Hsp_query-to>
      <Hsp_hit-from>17</Hsp_hit-from>
      <Hsp_hit-to>295</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>132</Hsp_positive>
      <Hsp_gaps>70</Hsp_gaps>
      <Hsp_align-len>300</Hsp_align-len>
      <Hsp_qseq>LRAAMDNFQKVEKIGEGTYGVVYKARNKLTGEA---VALKKI-RLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFE--------LLDQDLKKFMDN---------------ATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAE---------------------GAIKLADFGLARAFGVPQRTYTHEVV-TLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVSQLPDYKSTFPRWANQE</Hsp_qseq>
      <Hsp_hseq>LMASAGNYTAEKEIGKGSFATVY--RGHLTSDKSQHVAIKEVSRAKLKNKKLLENLEIEIAILKKIKHPHIVGLIDCERTSTDFYLIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARF--LPNTSLAETLCGSPLYMAPEI-LNYQKYNAKADLWSVGTVVFEMCCGTPPFRASNHLE----LFKKIKRANDVI------------TFPSYCNIE</Hsp_hseq>
      <Hsp_midline>L A+  N+   ++IG+G++  VY  R  LT +    VA+K++ R   + + +      EI++L+++ HP+IV L+    +    YL+ E         L +  K+ M+N                  +G+    V SYL QL   + F  S  ++HRD+KPQNLL++                         +K+ADFG AR   +P  +    +  +  Y APEI L  + Y+   D+WS+G +  EM      F   + ++    +F+ +   ++V+            TFP + N E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.1149</Hsp_bit-score>
      <Hsp_score>209</Hsp_score>
      <Hsp_evalue>1.48809e-17</Hsp_evalue>
      <Hsp_query-from>285</Hsp_query-from>
      <Hsp_query-to>941</Hsp_query-to>
      <Hsp_hit-from>546</Hsp_hit-from>
      <Hsp_hit-to>786</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>245</Hsp_align-len>
      <Hsp_qseq>FQKVEKIGEGTYGVVYKAR-------------------NKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLL-TIIHSEKKLYLVFELLDQ-DLKKFMDNATP---SGIPL--PLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTP</Hsp_qseq>
      <Hsp_hseq>FKVIEKAGQGASGSVYLAERTHIPTESNMIELINNDIDEPHVGDKVAIKQMVLSKQPRK--ELIVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEV-VKQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALY-LIATNGTP</Hsp_hseq>
      <Hsp_midline>F+ +EK G+G  G VY A                        G+ VA+K++ L  +        + EI ++++  H NIV  L   + ++  L++V E ++   L   ++N+     S  PL  P +   + +  QG+ F H   I+HRD+K  N+L++    +K+ DFG        +      V T ++ APE+ +  + Y   +DVWS+G +  EML     +  +  +  L+ +  T GTP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.9593</Hsp_bit-score>
      <Hsp_score>206</Hsp_score>
      <Hsp_evalue>2.05015e-17</Hsp_evalue>
      <Hsp_query-from>279</Hsp_query-from>
      <Hsp_query-to>899</Hsp_query-to>
      <Hsp_hit-from>219</Hsp_hit-from>
      <Hsp_hit-to>425</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>214</Hsp_align-len>
      <Hsp_qseq>DNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIR-LDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKK--LYLVFELLD-QDLKKFMDNATPSG--IPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLA-RAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSE</Hsp_qseq>
      <Hsp_hseq>DRIETLGILGEGAGGSVSKCKLKNGSKIFALKVINTLNTDPE-YQKQIFRELQFNRSFQSEYIVRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVSGEAVNSLATTFTG---TSFYMAPERIQG-QPYSVTSDVWSLGLTILEVANGK--FPCSSE</Hsp_hseq>
      <Hsp_midline>D  + +  +GEG  G V K + K   +  ALK I  L+T+ E       RE+   R      IVR   +   ++   +Y+  E +  + L     N    G  I   ++      +L+G+++ H  +++HRD+KPQN+L+N  G +KL DFG++  A      T+T    T +Y APE + G + YS + DVWS+G    E+   +  FP  SE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YOR267C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:822588:824867:-1 gene:YOR267C transcript:YOR267C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRK1 description:Protein kinase; implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005793]</Hit_def>
  <Hit_accession>YOR267C</Hit_accession>
  <Hit_len>759</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>84.3445</Hsp_bit-score>
      <Hsp_score>207</Hsp_score>
      <Hsp_evalue>2.15865e-17</Hsp_evalue>
      <Hsp_query-from>303</Hsp_query-from>
      <Hsp_query-to>950</Hsp_query-to>
      <Hsp_hit-from>221</Hsp_hit-from>
      <Hsp_hit-to>440</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>226</Hsp_align-len>
      <Hsp_qseq>IGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIR---EISLLRELNHPNIVRLLTIIHSEK--KLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQR---TYTHEVV-TLWYRAPEILLGCKHYSTS-VDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDEV</Hsp_qseq>
      <Hsp_hseq>LGSGAGGSVKVLVRPTDGATFAVKEFRPRKPNESVKEYAKKCTAEFCIGSTLHHPNVIETVDVFSDSKQNKYYEVMEYCPID---FFAVVMTGKMSRGEINCCLKQLTEGVKYLHSMGLAHRDLKLDNCVMTSQGILKLIDFGSAVVFRYPFEDGVTMAHGIVGSDPYLAPEVITSTKSYDPQCVDIWSIGIIYCCMVLKRFPWKAPRDSDDNFRLY---CMPDDI</Hsp_hseq>
      <Hsp_midline>+G G  G V        G   A+K+ R     E V   A +   E  +   L+HPN++  + +    K  K Y V E    D   F        +    +   L QL +G+ + HS  + HRDLK  N ++ ++G +KL DFG A  F  P     T  H +V +  Y APE++   K Y    VD+WSIG I+  M+ +R  +    + D  FR++     PD++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.4185</Hsp_bit-score>
      <Hsp_score>202</Hsp_score>
      <Hsp_evalue>2.38742e-17</Hsp_evalue>
      <Hsp_query-from>285</Hsp_query-from>
      <Hsp_query-to>884</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>222</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>225</Hsp_align-len>
      <Hsp_qseq>FQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELN-HPNIVRLLTIIHSEKKLYLVFELLD-QDLKKFMDNA-------TPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLG-----C--KHYSTS---------VDVWSIGCIFAEMLTRRALF</Hsp_qseq>
      <Hsp_hseq>YTKLRSIQSGTFSTVYKAWSTTHNRYVALKITPKYKTSEANMKNEYDVMKILSSCNPHPNICSMLDFYTDDSYYIMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQIDMQK-IIKQLCSAISFAHSLGIAHRDIKPENILLTINGDIKLADWG--HAIQSP-KSNDFQIGTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFGDCLF</Hsp_hseq>
      <Hsp_midline>+ K+  I  GT+  VYKA +      VALK       +E         + +L   N HPNI  +L     +    +V E  +  DL  F+D A       +PS I + + K  + QL   I+F HS  I HRD+KP+N+L+   G IKLAD+G   A   P ++   ++ T  YRAPE   G     C  K++  S          D WS+G     ++    LF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YHR079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:258244:261591:-1 gene:YHR079C transcript:YHR079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IRE1 description:Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; role in homeostatic adaptation to ER stress; Kar2p binds inactive Ire1p and releases from it upon ER stress [Source:SGD;Acc:S000001121]</Hit_def>
  <Hit_accession>YHR079C</Hit_accession>
  <Hit_len>1115</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>84.3445</Hsp_bit-score>
      <Hsp_score>207</Hsp_score>
      <Hsp_evalue>3.12074e-17</Hsp_evalue>
      <Hsp_query-from>273</Hsp_query-from>
      <Hsp_query-to>872</Hsp_query-to>
      <Hsp_hit-from>669</Hsp_hit-from>
      <Hsp_hit-to>916</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>121</Hsp_positive>
      <Hsp_gaps>60</Hsp_gaps>
      <Hsp_align-len>254</Hsp_align-len>
      <Hsp_qseq>AMDNFQKVEKI-GEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELN-HPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSY-----LYQLLQGIAFCHSHRILHRDLKPQNLLINAE---------GA----IKLADFGLARAFGVPQRTY----THEVVTLWYRAPEIL-----LGCK----HYST---------------------SVDVWSIGCIFAEMLTR</Hsp_qseq>
      <Hsp_hseq>SLKNLVVSEKILGYGSSGTVV-FQGSFQGRPVAVKRMLID-----FCDIALMEIKLLTESDDHPNVIRYYCSETTDRFLYIALELCNLNLQDLVESKNVSDENLKLQKEYNPISLLRQIASGVAHLHSLKIIHRDLKPQNILVSTSSRFTADQQTGAENLRILISDFGLCKKLDSGQSSFRTNLNNPSGTSGWRAPELLEESNNLQCQVETEHSSSRHTVVSSDSFYDPFTKRRLTRSIDIFSMGCVFYYILSK</Hsp_hseq>
      <Hsp_midline>++ N    EKI G G+ G V   +    G  VA+K++ +D         A+ EI LL E + HPN++R      +++ LY+  EL + +L+  +++   S   L L K Y     L Q+  G+A  HS +I+HRDLKPQN+L++           GA    I ++DFGL +     Q ++     +   T  +RAPE+L     L C+    H S+                     S+D++S+GC+F  +L++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.5741</Hsp_bit-score>
      <Hsp_score>205</Hsp_score>
      <Hsp_evalue>3.93985e-17</Hsp_evalue>
      <Hsp_query-from>297</Hsp_query-from>
      <Hsp_query-to>920</Hsp_query-to>
      <Hsp_hit-from>15</Hsp_hit-from>
      <Hsp_hit-to>242</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>243</Hsp_align-len>
      <Hsp_qseq>EKIGEGTYGVVYKA-----RNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLV-----------KSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAF-----------------GVPQRTYTHEVVTLWYRAPEILL--GCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRI</Hsp_qseq>
      <Hsp_hseq>EELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQKHHAGIIKLYYTFHDEENLYFVLDF------------APGGELLSLLHKMGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQCGYGS---DIWALGCMIYQFVQGQPPFRGENELKTFEKI</Hsp_hseq>
      <Hsp_midline>E++G G+Y  V+KA      NK+    V  KK  +        +     ++LL + +H  I++L    H E+ LY V +              P G  L L+           + +  QL+  + F HSH I+HRDLKP+N+L++ +G + + DFG A                        +     V T  Y +PE+LL   C + S   D+W++GC+  + +  +  F G++E+    +I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YDL214C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:74446:76545:-1 gene:YDL214C transcript:YDL214C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR2 description:Serine/threonine protein kinase; inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance; PRR2 has a paralog, NPR1, that arose from the whole genome duplication [Source:SGD;Acc:S000002373]</Hit_def>
  <Hit_accession>YDL214C</Hit_accession>
  <Hit_len>699</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.1889</Hsp_bit-score>
      <Hsp_score>204</Hsp_score>
      <Hsp_evalue>4.99187e-17</Hsp_evalue>
      <Hsp_query-from>303</Hsp_query-from>
      <Hsp_query-to>887</Hsp_query-to>
      <Hsp_hit-from>367</Hsp_hit-from>
      <Hsp_hit-to>563</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>202</Hsp_align-len>
      <Hsp_qseq>IGEGTYGVVYKARNKLTGEAVALKKIRLDTETEG---VPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHE----VVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFP</Hsp_qseq>
      <Hsp_hseq>LGEGSGGKVKLVQRVLDNKVFALKEYRSKKKRESERKYIKNIISEYCIASTLKNPNICETLEILYEKGKIFQILEYCEYDLFSLV---MSEKMHYEEICCLFKQLINGVKYLHDIGLSHRDLKLDNCVVTRRGILKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFYFNEYDPRALDVWSVGIIFFCMITRR--FP</Hsp_hseq>
      <Hsp_midline>+GEG+ G V   +  L  +  ALK+ R   + E         I E  +   L +PNI   L I++ + K++ + E  + DL   +       +    +     QL+ G+ + H   + HRDLK  N ++   G +KL DFG +  F  P  +   E    V +  Y +PE+    ++   ++DVWS+G IF  M+TRR  FP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.0333</Hsp_bit-score>
      <Hsp_score>201</Hsp_score>
      <Hsp_evalue>7.24793e-17</Hsp_evalue>
      <Hsp_query-from>297</Hsp_query-from>
      <Hsp_query-to>869</Hsp_query-to>
      <Hsp_hit-from>19</Hsp_hit-from>
      <Hsp_hit-to>217</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>201</Hsp_align-len>
      <Hsp_qseq>EKIGEGTYGVVYKARNKLTGEAV-ALKKIRLDT-ETEGVPSTAI-REISLLRELN-HPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPS-GIPLPLVKSYLYQLLQGIAFCHSH-RILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQ---RTYTHEVVTLWYRAPEILLGCK-HYSTSVDVWSIGCIFAEMLT</Hsp_qseq>
      <Hsp_hseq>DTVGQGAFACVKNAHLQMDPSIILAVKFIHVPTCKKMGLSDKDITKEVVLQSKCSKHPNVLRLIDCNVSKEYMWIILEMADG--GDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLT</Hsp_hseq>
      <Hsp_midline>+ +G+G +  V  A  ++    + A+K I + T +  G+    I +E+ L  + + HPN++RL+    S++ ++++ E+ D       D   P  G+   + + Y  QL+  I + H    + HRD+KP+N+L++  G +KLADFGLA  F       R    +  +  Y APE+L   + +Y+   D+WSIG +   +LT</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YFL033C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:69115:74427:-1 gene:YFL033C transcript:YFL033C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM15 description:Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase [Source:SGD;Acc:S000001861]</Hit_def>
  <Hit_accession>YFL033C</Hit_accession>
  <Hit_len>1770</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.8037</Hsp_bit-score>
      <Hsp_score>203</Hsp_score>
      <Hsp_evalue>1.04058e-16</Hsp_evalue>
      <Hsp_query-from>273</Hsp_query-from>
      <Hsp_query-to>728</Hsp_query-to>
      <Hsp_hit-from>790</Hsp_hit-from>
      <Hsp_hit-to>942</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>161</Hsp_align-len>
      <Hsp_qseq>AMDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLREL-----NHPNIVRLLTIIHSEKKLYLVFELLD----QDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARA</Hsp_qseq>
      <Hsp_hseq>SIKDYDILKPISKGAYGSVYLARKKLTGDYFAIKVLR---KSDMIAKNQVTNVKSERAIMMVQSDKPYVARLFASFQNKDNLFLVMEYLPGGDLATLIKMM-----GYLPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLIDNAGHVKLTDFGLSRA</Hsp_hseq>
      <Hsp_midline>++ ++  ++ I +G YG VY AR KLTG+  A+K +R   +++ +    +  +   R +     + P + RL     ++  L+LV E L       L K M       +P    K YL +++ G+   H + I+H DLKP+NLLI+  G +KL DFGL+RA</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.2629</Hsp_bit-score>
      <Hsp_score>199</Hsp_score>
      <Hsp_evalue>1.68238e-16</Hsp_evalue>
      <Hsp_query-from>267</Hsp_query-from>
      <Hsp_query-to>914</Hsp_query-to>
      <Hsp_hit-from>354</Hsp_hit-from>
      <Hsp_hit-to>573</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>RAAMDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLD-QDLKKFMDNATP-SGIPLPLVKSYLYQLLQGIA-FCHSHRILHRDLKPQNLLINA-EGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCK----HYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLF</Hsp_qseq>
      <Hsp_hseq>RITLDELEFLDELGHGNYGNVSKVLHKPTNVIMATKEVRLELD-EAKFRQILMELEVLHKCNSPYIVDFYGAFFIEGAVYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSANQGTVKLCDFGVSGNL-VASLAKTN-IGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYPPET-YDNIF</Hsp_hseq>
      <Hsp_midline>R  +D  + ++++G G YG V K  +K T   +A K++RL+ + E      + E+ +L + N P IV        E  +Y+  E +D   L K  D ++   GI  P +      ++ G+      H I+HRD+KP N+L +A +G +KL DFG++    V     T+ +    Y APE +         Y+   D+WS+G    EM   R  +P ++  D +F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.8777</Hsp_bit-score>
      <Hsp_score>198</Hsp_score>
      <Hsp_evalue>2.668e-16</Hsp_evalue>
      <Hsp_query-from>282</Hsp_query-from>
      <Hsp_query-to>863</Hsp_query-to>
      <Hsp_hit-from>411</Hsp_hit-from>
      <Hsp_hit-to>605</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>206</Hsp_align-len>
      <Hsp_qseq>NFQKVEKIGEGTYGVVYKARNKLTGEAVALK---KIRLDTETEGVPSTAIREISLLR-ELNHPNIVRLLTIIHSEKKLYLVFELLD--------QDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEM</Hsp_qseq>
      <Hsp_hseq>DFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDR---------AKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKA-DLKDRTNTF-CGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEM</Hsp_hseq>
      <Hsp_midline>+F+ +  +G+GT+G VY+ + K T    A+K   K  +  + E   +   R I +     + P IV L     +   LYLV + +         Q   +F ++           K Y+ +L+  +   H + I++RDLKP+N+L++A G I L DFGL++A  +  RT T    T  Y APE+LL    Y+  VD WS+G +  EM</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YNL183C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:293137:295509:-1 gene:YNL183C transcript:YNL183C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NPR1 description:Protein kinase; stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p; negatively regulates Ldb19p-mediated endocytosis through phosphorylation of Ldb19p, which prevents its association with the plasma membrane; Npr1p activity is negatively regulated via phosphorylation by the TOR complex; NPR1 has a paralog, PRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005127]</Hit_def>
  <Hit_accession>YNL183C</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.1073</Hsp_bit-score>
      <Hsp_score>196</Hsp_score>
      <Hsp_evalue>5.30909e-16</Hsp_evalue>
      <Hsp_query-from>447</Hsp_query-from>
      <Hsp_query-to>923</Hsp_query-to>
      <Hsp_hit-from>495</Hsp_hit-from>
      <Hsp_hit-to>654</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>164</Hsp_align-len>
      <Hsp_qseq>LNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKF-MDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHE----VVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIF</Hsp_qseq>
      <Hsp_hseq>LNHPNIIETIEIVYENDRILQVMEYCEYDLFAIVMSNK----MSYEEICCCFKQILTGVQYLHSIGLAHRDLKLDNCVINEKGIVKLIDFGAAVVFSYPFSKNLVEASGIVGSDPYLAPEVCIFAKYDPRPVDIWSSAIIFACMILKKFPWKIPKLRDNSFKLF</Hsp_hseq>
      <Hsp_midline>LNHPNI+  + I++   ++  V E  + DL    M N     +    +     Q+L G+ + HS  + HRDLK  N +IN +G +KL DFG A  F  P      E    V +  Y APE+ +  K+    VD+WS   IFA M+ ++  +      D  F++F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.7221</Hsp_bit-score>
      <Hsp_score>195</Hsp_score>
      <Hsp_evalue>7.58825e-16</Hsp_evalue>
      <Hsp_query-from>267</Hsp_query-from>
      <Hsp_query-to>884</Hsp_query-to>
      <Hsp_hit-from>93</Hsp_hit-from>
      <Hsp_hit-to>323</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>237</Hsp_align-len>
      <Hsp_qseq>RAAMDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTET-----EGVPST----------------------AIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIA----FCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALF</Hsp_qseq>
      <Hsp_hseq>RRSLGDWEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESEILERQKRLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGG--QLLDYIIQHGS---LKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYRKQLHTF-CGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPF</Hsp_hseq>
      <Hsp_midline>R ++ +++ +E +G G+ G V   +++ T E   +K +   ++        +PS                        +RE SL + L HP+I RL  +       Y++FE +     + +D     G    L + +  +  +GIA    + H++ I+HRDLK +N++I++ G IK+ DFGL+  F   ++ +T    +L++ APE+L    +    VD+WS G +   ++  +  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.5666</Hsp_bit-score>
      <Hsp_score>192</Hsp_score>
      <Hsp_evalue>1.17592e-15</Hsp_evalue>
      <Hsp_query-from>264</Hsp_query-from>
      <Hsp_query-to>941</Hsp_query-to>
      <Hsp_hit-from>170</Hsp_hit-from>
      <Hsp_hit-to>437</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>56</Hsp_gaps>
      <Hsp_align-len>275</Hsp_align-len>
      <Hsp_qseq>LRAAMDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLD-----TETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELL-DQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQR---------------------------------------TYTHEVV-TLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDS---EIDQLFRIFRTLGTP</Hsp_qseq>
      <Hsp_hseq>LKPKNRDFEMITQVGQGGYGQVYLARKKDTKEVCALKILNKKLLFKLNETKHV----LTERDILTTTRSEWLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINT--RCLKSGHARFYISEMFCAVNALHDLGYTHRDLKPENFLIDAKGHIKLTDFGLAAGTISNERIESMKIRLEKIKDLEFPAFTEKSIEDRRKMYNQLREKEINYANSMVGSPDYMALEVLEG-KKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYDNLRRWKQTLRRP</Hsp_hseq>
      <Hsp_midline>L+    +F+ + ++G+G YG VY AR K T E  ALK +         ET+ V    + E  +L       +V+LL      + LYL  E +   D +  + N     +     + Y+ ++   +   H     HRDLKP+N LI+A+G IKL DFGLA      +R                                        Y + +V +  Y A E+L G K Y  +VD WS+GC+  E L     F G S     D L R  +TL  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.9518</Hsp_bit-score>
      <Hsp_score>193</Hsp_score>
      <Hsp_evalue>1.30846e-15</Hsp_evalue>
      <Hsp_query-from>267</Hsp_query-from>
      <Hsp_query-to>854</Hsp_query-to>
      <Hsp_hit-from>114</Hsp_hit-from>
      <Hsp_hit-to>334</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>RAAMDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTET-----EGVP----------------------STAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSG-IPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIF</Hsp_qseq>
      <Hsp_hseq>RKSLGDWEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPPPKNEQDVLERQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGG--QLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIYDSRKQLHTF-CGSLYFAAPELLKANPYTGPEVDVWSFGVVL</Hsp_hseq>
      <Hsp_midline>R ++ +++ VE +G G+ G V  A+++ T E  A+K +   T+      + +P                         IRE SL + L HP+I RL  +       Y++FE +     + +D     G I     + +   +   + + H++ I+HRDLK +N++I+    IK+ DFGL+  +   ++ +T    +L++ APE+L    +    VDVWS G + </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.9518</Hsp_bit-score>
      <Hsp_score>193</Hsp_score>
      <Hsp_evalue>1.33266e-15</Hsp_evalue>
      <Hsp_query-from>285</Hsp_query-from>
      <Hsp_query-to>974</Hsp_query-to>
      <Hsp_hit-from>496</Hsp_hit-from>
      <Hsp_hit-to>742</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>114</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>256</Hsp_align-len>
      <Hsp_qseq>FQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLREL----NHPNIVRLLTIIHSEKKLYLVFEL-LDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGL---ARAFGVP------QRTYTHE------------VVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVSQL</Hsp_qseq>
      <Hsp_hseq>FEKIRLLGQGDVGKVFLVREKKTNRVYALKVLSKD---EMIKRNKIKRVLTEQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRGNGH-TAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILK-----NEVSFPNNNEI</Hsp_hseq>
      <Hsp_midline>F+K+  +G+G  G V+  R K T    ALK +  D   E +    I+ +   +E+    NHP IV L     SE  LYL  E  +  +  + +       I     + Y  ++   + + H    ++RDLKP+N+L++  G I L+DF L   A+   VP      Q T                V T  Y APE++ G  H + +VD W++G +  EML     F GD+  +    I +     +EV +P  +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.5666</Hsp_bit-score>
      <Hsp_score>192</Hsp_score>
      <Hsp_evalue>1.48232e-15</Hsp_evalue>
      <Hsp_query-from>303</Hsp_query-from>
      <Hsp_query-to>1001</Hsp_query-to>
      <Hsp_hit-from>52</Hsp_hit-from>
      <Hsp_hit-to>287</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>246</Hsp_align-len>
      <Hsp_qseq>IGEGTYGVVYKARNKLTG-----EAVALKKIRLDTETEGVPS--TAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQ-DLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHY-STSVDVWSIGCIFAEMLTRRALFPGDSEI---DQLFRIFRTL-GTPDEVVWPGVSQLPDYKSTFPR</Hsp_qseq>
      <Hsp_hseq>LGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRK--RRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARLYKYITQTP--------LKFPEYITPIPR</Hsp_hseq>
      <Hsp_midline>+GEG +G V     K +      + VA+K IR DT  +         REI+ L+ L HPNI+ L  ++ + K + +V E +   +  K++       +          QL+ G+ + H   ++HRDLK +NLL++    + + DFG    F            +  Y APE+++  K Y +   DVWS G I   ML     +  D E    D + R+++ +  TP         + P+Y +  PR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YFL029C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:78055:79161:-1 gene:YFL029C transcript:YFL029C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CAK1 description:Cyclin-dependent kinase-activating kinase; required for passage through the cell cycle; phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases [Source:SGD;Acc:S000001865]</Hit_def>
  <Hit_accession>YFL029C</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.2554</Hsp_bit-score>
      <Hsp_score>186</Hsp_score>
      <Hsp_evalue>2.33885e-15</Hsp_evalue>
      <Hsp_query-from>354</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>25</Hsp_hit-from>
      <Hsp_hit-to>289</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>118</Hsp_positive>
      <Hsp_gaps>67</Hsp_gaps>
      <Hsp_align-len>269</Hsp_align-len>
      <Hsp_qseq>GEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSE----KKLYLVFELLDQDLKKFM---------------DNATPSGIPL----PLVK------------SYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGA-----IKLADFGL-------ARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPG------DSEIDQL------FR----IFRTLGTPDEVVWPGVSQ</Hsp_qseq>
      <Hsp_hseq>SDTYAIKCLALDFDIP--PHNAKFEVSILNKLGN-KCKHILPLLESKATDNNDLLLLFPFEEMNLYEFMQMHYKRDRRKKNPYYDLLNPS-IPIVADPPVQKYTNQLDVNRYSLSFFRQMVEGIAFLHENKIIHRDIKPQNIMLTNNTSTVSPKLYIIDFGISYDMANNSQTSAEPMDSKVTDISTGIYKAPEVLFGVKCYDGGVDVWSLLIIISQWFQRETSRMGHVPAMIDDGSDDMNSDGSDFRLICSIFEKLGIPSIQKWEEVAQ</Hsp_hseq>
      <Hsp_midline> +  A+K + LD +    P  A  E+S+L +L +     +L ++ S+      L L+F   + +L +FM               D   PS IP+    P+ K            S+  Q+++GIAF H ++I+HRD+KPQN+++    +     + + DFG+       ++    P  +   ++ T  Y+APE+L G K Y   VDVWS+  I ++   R     G      D   D +      FR    IF  LG P    W  V+Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>71</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.0258</Hsp_bit-score>
      <Hsp_score>188</Hsp_score>
      <Hsp_evalue>2.76319e-15</Hsp_evalue>
      <Hsp_query-from>276</Hsp_query-from>
      <Hsp_query-to>869</Hsp_query-to>
      <Hsp_hit-from>188</Hsp_hit-from>
      <Hsp_hit-to>399</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>216</Hsp_align-len>
      <Hsp_qseq>MDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELN-HPNIVRLLTII---HSEKKLYLVFEL-----LDQDL---KKFMDNATPSG----IPLPLVKSYLYQLLQGIAFCH-SHRILHRDLKPQNLLINAEGAIKLADFGLARAF-GVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLT</Hsp_qseq>
      <Hsp_hseq>LQDLVQLGKIGAGNSGTVVKALHVPDSKIVAKKTIPVEQNNSTIINQLVRELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKLINSIADTF---VGTSTYMSPERIQG-NVYSIKGDVWSLGLMIIELVT</Hsp_hseq>
      <Hsp_midline>+ +  ++ KIG G  G V KA +    + VA K I ++     + +  +RE+S+++ +  H NI+         H   ++ ++ E      LD+ L   K+F+   T S          +    Y +L G+   +  ++I+HRD+KP N+LIN++G IKL DFG+++        T+   V T  Y +PE + G   YS   DVWS+G +  E++T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>72</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.411</Hsp_bit-score>
      <Hsp_score>189</Hsp_score>
      <Hsp_evalue>4.55431e-15</Hsp_evalue>
      <Hsp_query-from>267</Hsp_query-from>
      <Hsp_query-to>866</Hsp_query-to>
      <Hsp_hit-from>127</Hsp_hit-from>
      <Hsp_hit-to>377</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>51</Hsp_gaps>
      <Hsp_align-len>251</Hsp_align-len>
      <Hsp_qseq>RAAMDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEG-----VPSTAI-------REISLLRELNHPNIVRLLTIIHS--EKKLYLVFELLDQDLKKF-------MDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLA--------------------------RAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIG----CIFAEML</Hsp_qseq>
      <Hsp_hseq>RKVLNTYEIIKELGHGQHGKVKLARDILSKQLVAIKIVDRHEKKQRKFFTFIKSSKISENDKIKREIAIMKKCHHKHVVQLIEVLDDLKSRKIYLVLEYCSRGEVKWCPPDCMESDAKGPSLLSFQETREILRGVVLGLEYLHYQGIIHRDIKPANLLISGDGTVKISDFGVSLAASSTNSSDSSESLDELELAKTVGTPAFFAPEMCLGEDAFTRYNLTKENLFRGSCISFMIDIWAVGVTLYCLLFGML</Hsp_hseq>
      <Hsp_midline>R  ++ ++ ++++G G +G V  AR+ L+ + VA+K +    + +      + S+ I       REI+++++ +H ++V+L+ ++     +K+YLV E   +   K+        D   PS +     +  L  ++ G+ + H   I+HRD+KP NLLI+ +G +K++DFG++                           AF  P+     +  T +    E L      S  +D+W++G    C+   ML</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>73</Hit_num>
  <Hit_id>YJR059W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:545787:548243:1 gene:YJR059W transcript:YJR059W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK2 description:Serine/threonine protein kinase; involved in regulation of ion transport across plasma membrane; carboxyl terminus is essential for glucose-dependent Pma1p activation via phosphorylation of Pma1p-Ser899; enhances spermine uptake; PTK2 has a paralog, PTK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003820]</Hit_def>
  <Hit_accession>YJR059W</Hit_accession>
  <Hit_len>818</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.6406</Hsp_bit-score>
      <Hsp_score>187</Hsp_score>
      <Hsp_evalue>6.23491e-15</Hsp_evalue>
      <Hsp_query-from>303</Hsp_query-from>
      <Hsp_query-to>923</Hsp_query-to>
      <Hsp_hit-from>261</Hsp_hit-from>
      <Hsp_hit-to>495</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>236</Hsp_align-len>
      <Hsp_qseq>IGEGTYGVVYKARNKLTGEAV-ALKKIRL--DTETEGVPSTAIREISLLRELNHPNI--------VRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLW-------YRAPEILL--GCKHYST---------SVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIF</Hsp_qseq>
      <Hsp_hseq>IGSGGSSEVRKVKSSYRQKDVYALKKLNMIYHESPEKFYKRCSKEFIIAKHLSH-NVHITNTFYLLKVPTTTYTTRGWGFIMELGVKDLFQLMERTGWKNVPFNEKYCLFKQVAQGIKFCHDNGIAHRDLKPENVLISKEGICKLTDFGISDWYHVIPHDYTSPVKTCQGMIGSPPYTPPEVMYFDAKKHYPEKFQKPYNPLAMDSYALGIMLITMINNIIPFIDSCNTDARFREF</Hsp_hseq>
      <Hsp_midline>IG G    V K ++    + V ALKK+ +      E       +E  + + L+H N+        +++ T  ++ +    + EL  +DL + M+      +P         Q+ QGI FCH + I HRDLKP+N+LI+ EG  KL DFG++  + V    YT  V T         Y  PE++     KHY           ++D +++G +   M+     F      D  FR F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>74</Hit_num>
  <Hit_id>YLL019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:105686:107899:-1 gene:YLL019C transcript:YLL019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KNS1 description:Protein kinase involved in negative regulation of PolIII transcription; effector kinase of the TOR signaling pathway and phosphorylates Rpc53p to regulate ribosome and tRNA biosynthesis; member of the LAMMER family of protein kinases, which are serine/threonine kinases also capable of phosphorylating tyrosine residues; capable of autophosphorylation [Source:SGD;Acc:S000003942]</Hit_def>
  <Hit_accession>YLL019C</Hit_accession>
  <Hit_len>737</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.0998</Hsp_bit-score>
      <Hsp_score>183</Hsp_score>
      <Hsp_evalue>1.49216e-14</Hsp_evalue>
      <Hsp_query-from>303</Hsp_query-from>
      <Hsp_query-to>941</Hsp_query-to>
      <Hsp_hit-from>319</Hsp_hit-from>
      <Hsp_hit-to>563</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>251</Hsp_align-len>
      <Hsp_qseq>IGEGTYGVVYKA-RNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPN----IVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEG--------------------------------AIKLADFGLARAFGVPQRTYTHEVV-TLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTP</Hsp_qseq>
      <Hsp_hseq>LGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDRYREAAKTELRILQTILN-NDPQGQFQCLLLRECFDYKNHICLVTDLYGRSIYDFMCSNGIARFPGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENILICDETHIAQKLPLKTVQSLSKRRREASKGKRKILKNPEIKIIDFGSA----IFHYEYHPPVISTRHYRAPEIVLGLG-WSFPCDIWSIACVLVELVIGESLYPIHENLEHMAMMQRINGTP</Hsp_hseq>
      <Hsp_midline>+G+GT+G V K   NK     VA+K IR          T +R +  +   N P      + L      +  + LV +L  + +  FM +   +  P   +++   QL++ + F H   I+H DLKP+N+LI  E                                  IK+ DFG A    +    Y   V+ T  YRAPEI+LG   +S   D+WSI C+  E++   +L+P    ++ +  + R  GTP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>75</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.485</Hsp_bit-score>
      <Hsp_score>184</Hsp_score>
      <Hsp_evalue>1.7277e-14</Hsp_evalue>
      <Hsp_query-from>282</Hsp_query-from>
      <Hsp_query-to>902</Hsp_query-to>
      <Hsp_hit-from>1095</Hsp_hit-from>
      <Hsp_hit-to>1310</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>223</Hsp_align-len>
      <Hsp_qseq>NFQKVEKIGEGTYGVVYKARNKLTGEAVALK-----KIRLDT----ETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQ-------DLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEI</Hsp_qseq>
      <Hsp_hseq>DFVSLQKMGEGAYGKVNLCIHKKNRYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKKPHENILRLLDFFEDDDYYYIETPVHGETGCIDLFDLIEFKTNMTEFE-----AKLIFKQVVAGIKHLHDQGIVHRDIKDENVIVDSKGFVKIIDFGSAAY--VKSGPFDVFVGTIDYAAPEVLGGNPYEGQPQDIWAIGILLYTVVFKENPFYNIDEI</Hsp_hseq>
      <Hsp_midline>+F  ++K+GEG YG V    +K     V +K     +I +DT       G   + I+ ++ L +  H NI+RLL     +   Y+   +  +       DL +F  N T         K    Q++ GI   H   I+HRD+K +N++++++G +K+ DFG A    V    +   V T+ Y APE+L G  +     D+W+IG +   ++ +   F    EI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>76</Hit_num>
  <Hit_id>YAR018C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:170396:171703:-1 gene:YAR018C transcript:YAR018C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN3 description:Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol [Source:SGD;Acc:S000000071]</Hit_def>
  <Hit_accession>YAR018C</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.559</Hsp_bit-score>
      <Hsp_score>179</Hsp_score>
      <Hsp_evalue>3.09526e-14</Hsp_evalue>
      <Hsp_query-from>285</Hsp_query-from>
      <Hsp_query-to>905</Hsp_query-to>
      <Hsp_hit-from>25</Hsp_hit-from>
      <Hsp_hit-to>295</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>66</Hsp_gaps>
      <Hsp_align-len>272</Hsp_align-len>
      <Hsp_qseq>FQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKK--LYLVFELLDQ-DLKKFMDNATPSG--IPLPLVKSYLYQLLQGIAFCH---------------------SHRILHRDLKPQNLLINAEGA---------------------------------------IKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEID</Hsp_qseq>
      <Hsp_hseq>YQVLEEIGRGSFGSVRKVIHIPTKKLLVRKDIKYGHMNSKERQQLIAECSILSQLKHENIVEFYNWDFDEQKEVLYLYMEYCSRGDLSQMIKHYKQEHKYIPEKIVWGILAQLLTALYKCHYGVELPTLTTIYDRMKPPVKGKNIVIHRDLKPGNIFLSYDDSDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLAKSLETSIQFATTYVGTPYYMSPEVLMD-QPYSPLSDIWSLGCVIFEMCSLHPPFQAKNYLE</Hsp_hseq>
      <Hsp_midline>+Q +E+IG G++G V K  +  T + +  K I+            I E S+L +L H NIV        E+K  LYL  E   + DL + + +       IP  +V   L QLL  +  CH                      + ++HRDLKP N+ ++ + +                                       +KL DFGLA++     +  T  V T +Y +PE+L+  + YS   D+WS+GC+  EM +    F   + ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>77</Hit_num>
  <Hit_id>YPR111W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:747306:749000:1 gene:YPR111W transcript:YPR111W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF20 description:Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006315]</Hit_def>
  <Hit_accession>YPR111W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.9442</Hsp_bit-score>
      <Hsp_score>180</Hsp_score>
      <Hsp_evalue>3.14275e-14</Hsp_evalue>
      <Hsp_query-from>264</Hsp_query-from>
      <Hsp_query-to>896</Hsp_query-to>
      <Hsp_hit-from>162</Hsp_hit-from>
      <Hsp_hit-to>411</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>57</Hsp_gaps>
      <Hsp_align-len>259</Hsp_align-len>
      <Hsp_qseq>LRAAMDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLD-----TETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELL-DQDLKKFMDNAT--PSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQR---------------------------------------TYTHEVV-TLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDS</Hsp_qseq>
      <Hsp_hseq>LKPKHKDFQILTQVGQGGYGQVYLAKKKDSDEICALKILNKKLLFKLNETNHV----LTERDILTTTRSDWLVKLLYAFQDPESLYLAMEFVPGGDFRTLLINTRILKSG----HARFYISEMFCAVNALHELGYTHRDLKPENFLIDATGHIKLTDFGLAAGTVSNERIESMKIRLEEVKNLEFPAFTERSIEDRRKIYHNMRKTEINYANSMVGSPDYMALEVLEG-KKYDFTVDYWSLGCMLFESLVGYTPFSGSS</Hsp_hseq>
      <Hsp_midline>L+    +FQ + ++G+G YG VY A+ K + E  ALK +         ET  V    + E  +L       +V+LL      + LYL  E +   D +  + N     SG      + Y+ ++   +   H     HRDLKP+N LI+A G IKL DFGLA      +R                                        Y + +V +  Y A E+L G K Y  +VD WS+GC+  E L     F G S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>78</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.9442</Hsp_bit-score>
      <Hsp_score>180</Hsp_score>
      <Hsp_evalue>3.36254e-14</Hsp_evalue>
      <Hsp_query-from>285</Hsp_query-from>
      <Hsp_query-to>923</Hsp_query-to>
      <Hsp_hit-from>324</Hsp_hit-from>
      <Hsp_hit-to>555</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>236</Hsp_align-len>
      <Hsp_qseq>FQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLREL----NHPNIVRLLTIIHSEKKLYLVFE-LLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLA-RAFGVPQRTYTHE-----------------VVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIF</Hsp_qseq>
      <Hsp_hseq>FEKIRLLGQGDVGKVYLVRERDTNQIFALKVL---NKHEMIKRKKIKRVLTEQEILATSDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGH-TAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNIL</Hsp_hseq>
      <Hsp_midline>F+K+  +G+G  G VY  R + T +  ALK +    + E +    I+ +   +E+    +HP IV L     ++  LYL  E  +  +  + +       I     K Y  +++  + + H    ++RDLKP+N+L++  G + L+DF L+ +A G  + T                     V T  Y APE++ G  H + +VD W++G +  EML     F GD+  +    I </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>79</Hit_num>
  <Hit_id>YDL025C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:405344:407206:-1 gene:YDL025C transcript:YDL025C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RTK1 description:Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002183]</Hit_def>
  <Hit_accession>YDL025C</Hit_accession>
  <Hit_len>620</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.559</Hsp_bit-score>
      <Hsp_score>179</Hsp_score>
      <Hsp_evalue>4.48256e-14</Hsp_evalue>
      <Hsp_query-from>300</Hsp_query-from>
      <Hsp_query-to>923</Hsp_query-to>
      <Hsp_hit-from>307</Hsp_hit-from>
      <Hsp_hit-to>523</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>221</Hsp_align-len>
      <Hsp_qseq>KIGEGTYGVVYKARNKLTGEAVALKKIR---LDTETEGVPSTA------IREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQR---TYTHEVV-TLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIF</Hsp_qseq>
      <Hsp_hseq>KLGEGASGSV-SVVERTDGKLFACKMFRKPHLNNEGTNQSQLANYSKKVTTEFCIGSTLHHENIVETLDMLTEGDTYLLVMEYAPYD---FFNLVMSNLMTQDEVNCYFKQLCHGVNYLHSMGLAHRDLKLDNCVVTKDGILKLIDFGSAVVFQYPYEDTIVKSHGIVGSDPYLAPELLKQTSYDPRVADVWSIAIIFYCMVLKRFPWKAPKKSFNSFRLF</Hsp_hseq>
      <Hsp_midline>K+GEG  G V     +  G+  A K  R   L+ E       A        E  +   L+H NIV  L ++       LV E    D   F +    + +    V  Y  QL  G+ + HS  + HRDLK  N ++  +G +KL DFG A  F  P       +H +V +  Y APE+L    +     DVWSI  IF  M+ +R  +    +    FR+F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>80</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.559</Hsp_bit-score>
      <Hsp_score>179</Hsp_score>
      <Hsp_evalue>4.86235e-14</Hsp_evalue>
      <Hsp_query-from>264</Hsp_query-from>
      <Hsp_query-to>899</Hsp_query-to>
      <Hsp_hit-from>118</Hsp_hit-from>
      <Hsp_hit-to>342</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>238</Hsp_align-len>
      <Hsp_qseq>LRAAMDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLD--TETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSY-----------LYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLAR---------AFGVPQ-RTYTHE---VVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSE</Hsp_qseq>
      <Hsp_hseq>VKMGIKDFKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQKLNGTKGIFKLFFTFQDEASLYFLLEY------------APHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPE-LLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANE</Hsp_hseq>
      <Hsp_midline>++  + +F+  E++G+G+Y  V  A  + +G+  A+K +  +     + V    + +++L +      I +L      E  LY + E              P G  L L+K Y             Q++  +   H+  I+HRD+KP+N+L++    +KL DFG A+         A G P    Y      V T  Y +PE LL   +  +  D+W+ GCI  +ML  +  F   +E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>81</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.9442</Hsp_bit-score>
      <Hsp_score>180</Hsp_score>
      <Hsp_evalue>5.16011e-14</Hsp_evalue>
      <Hsp_query-from>603</Hsp_query-from>
      <Hsp_query-to>866</Hsp_query-to>
      <Hsp_hit-from>818</Hsp_hit-from>
      <Hsp_hit-to>919</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>102</Hsp_align-len>
      <Hsp_qseq>QLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLAR------------AFGVP--QRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEML</Hsp_qseq>
      <Hsp_hseq>QILEALSYIHSQGIIHRDLKPMNIFIDESRNVKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVLDGTGHYNEKIDMYSLGIIFFEMI</Hsp_hseq>
      <Hsp_midline>Q+L+ +++ HS  I+HRDLKP N+ I+    +K+ DFGLA+            +  +P      T  + T  Y A E+L G  HY+  +D++S+G IF EM+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>1.51424e-06</Hsp_evalue>
      <Hsp_query-from>282</Hsp_query-from>
      <Hsp_query-to>470</Hsp_query-to>
      <Hsp_hit-from>598</Hsp_hit-from>
      <Hsp_hit-to>657</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>38</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>63</Hsp_align-len>
      <Hsp_qseq>NFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVR</Hsp_qseq>
      <Hsp_hseq>DFEEIAVLGQGAFGQVVKARNALDSRYYAIKKIR---HTEEKLSTILSEVMLLASLNHQYVVR</Hsp_hseq>
      <Hsp_midline>+F+++  +G+G +G V KARN L     A+KKIR    TE   ST + E+ LL  LNH  +VR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>82</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>2.08158e-13</Hsp_evalue>
      <Hsp_query-from>297</Hsp_query-from>
      <Hsp_query-to>914</Hsp_query-to>
      <Hsp_hit-from>320</Hsp_hit-from>
      <Hsp_hit-to>539</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>222</Hsp_align-len>
      <Hsp_qseq>EKIGEGTYGVVYKARNKLTGE----------AVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYL-VFELL-DQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTH----EVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLF</Hsp_qseq>
      <Hsp_hseq>EVLGKGAFGVVRICQKKNVSSQDGNKSEKLYAVKEFKRRTSESAEKYSKRLTSEFCISSSLHHTNIVTTLDLFQDAKGEYCEVMEYCAGGDL--FTLVVAAGKLEYMEADCFFKQLIRGVVYMHEMGVCHRDLKPENLLLTHDGVLKITDFGNSECFKMAWEKNIHLSGGVCGSSPYIAPEEYIKEEFDPRPVDIWACGVIYMAMRTGRQLWSSAEKDDPFY</Hsp_hseq>
      <Hsp_midline>E +G+G +GVV   + K              AV   K R     E        E  +   L+H NIV  L +    K  Y  V E     DL  F        +       +  QL++G+ + H   + HRDLKP+NLL+  +G +K+ DFG +  F +      H       +  Y APE  +  +     VD+W+ G I+  M T R L+    + D  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>83</Hit_num>
  <Hit_id>YJL165C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:106894:109461:-1 gene:YJL165C transcript:YJL165C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HAL5 description:Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters; HAL5 has a paralog, KKQ8, that arose from the whole genome duplication [Source:SGD;Acc:S000003701]</Hit_def>
  <Hit_accession>YJL165C</Hit_accession>
  <Hit_len>855</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>8.18035e-13</Hsp_evalue>
      <Hsp_query-from>447</Hsp_query-from>
      <Hsp_query-to>923</Hsp_query-to>
      <Hsp_hit-from>598</Hsp_hit-from>
      <Hsp_hit-to>783</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>186</Hsp_align-len>
      <Hsp_qseq>LNHPNIVRLLTIIHSEKKLYLVFE----------LLDQDLKKFMDNATP---------SGIPL-PL-VKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTH----EVVTLWYRAPEILLGCKHYSTS-VDVWSIGCIFAEMLTRRALFP-GDSEIDQLFRIF</Hsp_qseq>
      <Hsp_hseq>FNAPNILKILDLMEYSNSFVEVMEFCASGDLYSLLTRNNISNESNNGSSRLIQTVKEGSGSPLHPLEADCFMKQLLNGVQYMHDHGIAHCDLKPENILFQPNGLLKICDFGTSSVFQTAWEKHVHFQSGAMGSEPYVAPEEFIRDAEYDPRLVDCWSCGIVYCTMVMGQYLWKIAIPEKDSLFKSF</Hsp_hseq>
      <Hsp_midline> N PNI+++L ++        V E          L   ++    +N +          SG PL PL    ++ QLL G+ + H H I H DLKP+N+L    G +K+ DFG +  F      + H     + +  Y APE  +    Y    VD WS G ++  M+  + L+     E D LF+ F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>84</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>1.3538e-12</Hsp_evalue>
      <Hsp_query-from>303</Hsp_query-from>
      <Hsp_query-to>866</Hsp_query-to>
      <Hsp_hit-from>47</Hsp_hit-from>
      <Hsp_hit-to>246</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>202</Hsp_align-len>
      <Hsp_qseq>IGEGTYGVV-------YKARNKLTGE---AVALKKIRLDTETEGVPSTA--IREISLLRELNHPNIVRLLTIIHSEKKLYLVFELL-DQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYST-SVDVWSIGCIFAEML</Hsp_qseq>
      <Hsp_hseq>LGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRKEVKIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKR--RLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVNEFCSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAIL</Hsp_hseq>
      <Hsp_midline>+GEG +G V       +   +  T +    VA+K I+ D+ +          REI+ L+ L+HPNIV+L  ++ + + + +V E     +  K++       +          QL+ G+ + HS  ++HRDLK +NLL++    + + DFG    F            +  Y APE+++  + Y     D+WS G I   +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>85</Hit_num>
  <Hit_id>YDR247W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:956013:957398:1 gene:YDR247W transcript:YDR247W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VHS1 description:Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; VHS1 has a paralog, SKS1, that arose from the whole genome duplication [Source:SGD;Acc:S000002655]</Hit_def>
  <Hit_accession>YDR247W</Hit_accession>
  <Hit_len>461</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>1.60521e-12</Hsp_evalue>
      <Hsp_query-from>276</Hsp_query-from>
      <Hsp_query-to>923</Hsp_query-to>
      <Hsp_hit-from>9</Hsp_hit-from>
      <Hsp_hit-to>288</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>80</Hsp_gaps>
      <Hsp_align-len>288</Hsp_align-len>
      <Hsp_qseq>MDNFQKVEKIGEGTYGVVYKA---------------------------RNKLTGEAVALKK--IRLDTETEGV---PSTAI-----------------REISL-LRELNHPNIVRLLTIIHSEKKLYLVFELLDQDL-KKFMDNA--TPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTL---WYRAPEIL---------------LGCKHYSTSVDVWSIGCIFAEM-LTRRALFPGDSEIDQLFRIF</Hsp_qseq>
      <Hsp_hseq>INNYLITSQIGEGAYGLVYRALDIRTDRQYAIKAVVQSYGVSKEADMGNDKIHKNSVKLQKKLAKLFKESKNVVRVPSIDLESIENMSEEDFKKLPHYKEISLHLRVHHHKNIVTIHEVLQSAVCTFIVMDYYPTDLFTSIVDNRHFVTNGL---LVKKVFLQICSALNYCHEHGIYHCDIKPENLLLDTEDNVFLCDFGLSTT-----STYIKPNVCIGSSYYMPPERISFDGRVSSSKSGGHKLGKVCPSCNGDLWSLGIILINLTCIRNPWLKADKTEDNTYYYF</Hsp_hseq>
      <Hsp_midline>++N+    +IGEG YG+VY+A                            +K+   +V L+K   +L  E++ V   PS  +                 +EISL LR  +H NIV +  ++ S    ++V +    DL    +DN     +G+   LVK    Q+   + +CH H I H D+KP+NLL++ E  + L DFGL+        TY    V +   +Y  PE +               LG    S + D+WS+G I   +   R      D   D  +  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>86</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>3.52609e-12</Hsp_evalue>
      <Hsp_query-from>303</Hsp_query-from>
      <Hsp_query-to>893</Hsp_query-to>
      <Hsp_hit-from>168</Hsp_hit-from>
      <Hsp_hit-to>388</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>229</Hsp_align-len>
      <Hsp_qseq>IGEGTYGVVYKARNK--------LTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLL-TIIHSEKKLYLVFELL-DQDLKKFM---DNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGA---IKLADFGLARAFGVPQRTYTHEVVTLWYRAPEI----------------LLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGD</Hsp_qseq>
      <Hsp_hseq>VGNGTFGHVLITHNSKERDEDVCYHPENYAVKIIKLK------PNKFDKEARILLRLDHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLL--IVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGISPFYGD</Hsp_hseq>
      <Hsp_midline>+G GT+G V    N            E  A+K I+L       P+   +E  +L  L+HPNI+++  T       LY+  +L+   DL  ++   D  T       L+   ++Q+LQ + + H   I+HRDLK  N+L+        I LADFG+A+     +      V T  Y APE+                 L  + Y +  D+WS+G I   MLT  + F GD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>87</Hit_num>
  <Hit_id>YDL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:424209:425732:1 gene:YDL017W transcript:YDL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC7 description:DDK (Dbf4-dependent kinase) catalytic subunit; required for origin firing and replication fork progression in mitotic S phase through phosphorylation of Mcm2-7p complexes and Cdc45p; kinase activity correlates with cyclical DBF4 expression; required for pre-meiotic DNA replication, meiotic DSB formation, recruitment of monopolin complex to kinetochores during meiosis I, regulation of meiosis-specific Ndt80p; mutation complemented by human CDC7 and DBF4 co-expression [Source:SGD;Acc:S000002175]</Hit_def>
  <Hit_accession>YDL017W</Hit_accession>
  <Hit_len>507</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>7.11658e-12</Hsp_evalue>
      <Hsp_query-from>279</Hsp_query-from>
      <Hsp_query-to>728</Hsp_query-to>
      <Hsp_hit-from>31</Hsp_hit-from>
      <Hsp_hit-to>188</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>170</Hsp_align-len>
      <Hsp_qseq>DNFQKVEKIGEGTYGVVYKARNKLTGEA---------------VALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELL----DQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAE-GAIKLADFGLARA</Hsp_qseq>
      <Hsp_hseq>NEYKLIDKIGEGTFSSVYKAKD-ITGKITKKFASHFWNYGSNYVALKKIYVTSS----PQRIYNELNLLYIMTGSS--RVAPLCDAKRVRDQVIAVLPYYPHEEFRTFYRD-----LPIKGIKKYIWELLRALKFVHSKGIIHRDIKPTNFLFNLELGRGVLVDFGLAEA</Hsp_hseq>
      <Hsp_midline>+ ++ ++KIGEGT+  VYKA++ +TG+                VALKKI + +     P     E++LL  +   +  R+  +  +++    V  +L     ++ + F  +     +P+  +K Y+++LL+ + F HS  I+HRD+KP N L N E G   L DFGLA A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>88</Hit_num>
  <Hit_id>YKL198C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:68232:70220:-1 gene:YKL198C transcript:YKL198C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK1 description:Putative serine/threonine protein kinase; regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein; PTK1 has a paralog, PTK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001681]</Hit_def>
  <Hit_accession>YKL198C</Hit_accession>
  <Hit_len>662</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>1.12345e-11</Hsp_evalue>
      <Hsp_query-from>279</Hsp_query-from>
      <Hsp_query-to>923</Hsp_query-to>
      <Hsp_hit-from>191</Hsp_hit-from>
      <Hsp_hit-to>436</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>246</Hsp_align-len>
      <Hsp_qseq>DNF---QKVEKIGEGTYGVVYKARNKLTGEAV-ALKKIRL--DTETEGVPSTAIREISLLRELNHPN-------IVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLA-------RAFGVPQRTYTHEVVTLWYRAPEILL--GCKHYST---------SVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIF</Hsp_qseq>
      <Hsp_hseq>DNFVFDDENKTIGWGGSCEVRKIRSKYRKKDVFALKKLNMIYNETPEKFYKRCSKEFIIAKQLSHHVHITNTFLLVKVPTTVYTTRGWGFVMELGLRDLFAMIQKSGWRSVALAEKFCIFKQVACGVKFCHDQGIAHRDLKPENVLLSPDGVCKLTDFGISDWYHTDPHDLSSPVKKCAGMIGSPPYAPPEVMFYDSKKHYDTELQQPYDPRALDCYGLGIILMTLVNNVIPFLESCSFDTGFRDY</Hsp_hseq>
      <Hsp_midline>DNF    + + IG G    V K R+K   + V ALKK+ +  +   E       +E  + ++L+H         +V++ T +++ +    V EL  +DL   +  +    + L        Q+  G+ FCH   I HRDLKP+N+L++ +G  KL DFG++            P +     + +  Y  PE++     KHY T         ++D + +G I   ++     F      D  FR +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>89</Hit_num>
  <Hit_id>YKL168C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:131288:133462:-1 gene:YKL168C transcript:YKL168C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KKQ8 description:Putative serine/threonine protein kinase with unknown cellular role; KKQ8 has a paralog, HAL5, that arose from the whole genome duplication [Source:SGD;Acc:S000001651]</Hit_def>
  <Hit_accession>YKL168C</Hit_accession>
  <Hit_len>724</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>1.65906e-11</Hsp_evalue>
      <Hsp_query-from>360</Hsp_query-from>
      <Hsp_query-to>866</Hsp_query-to>
      <Hsp_hit-from>453</Hsp_hit-from>
      <Hsp_hit-to>638</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>186</Hsp_align-len>
      <Hsp_qseq>AVALKKIRLDTETEGVPSTAIREISLLRELNH---------PNIVRLLTIIHSEKKLYLVFELLDQ-DLKKFMDNATP-SGIPLPL-VKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHE----VVTLWYRAPEILLGCKHYSTS-VDVWSIGCIFAEML</Hsp_qseq>
      <Hsp_hseq>AVKELKPKPDSDLEKFCTKITSEFIIGHSLSHYHKNGKKPAPNILNVFDILEDSSSFIEVMEFCPAGDLYGMLVGKSKLKGRLHPLEADCFMKQLLHGVKFMHDHGIAHCDLKPENILFYPHGLLKICDFGTSSVFQTAWERRVHAQKGIIGSEPYVAPEEFVDGEYYDPRLIDCWSCGVVYITMI</Hsp_hseq>
      <Hsp_midline>AV   K + D++ E   +    E  +   L+H         PNI+ +  I+        V E     DL   +   +   G   PL    ++ QLL G+ F H H I H DLKP+N+L    G +K+ DFG +  F        H     + +  Y APE  +  ++Y    +D WS G ++  M+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>90</Hit_num>
  <Hit_id>YPL026C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:500675:502183:-1 gene:YPL026C transcript:YPL026C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKS1 description:Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway; SKS1 has a paralog, VHS1, that arose from the whole genome duplication [Source:SGD;Acc:S000005947]</Hit_def>
  <Hit_accession>YPL026C</Hit_accession>
  <Hit_len>502</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>2.34307e-11</Hsp_evalue>
      <Hsp_query-from>318</Hsp_query-from>
      <Hsp_query-to>875</Hsp_query-to>
      <Hsp_hit-from>73</Hsp_hit-from>
      <Hsp_hit-to>272</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>211</Hsp_align-len>
      <Hsp_qseq>YGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISL-LRELNHPNIVRLLTIIHSEKKLYLVFELLDQDL-------KKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLA--RAFGVPQRTYTHEVVTLWYRAPEILLGCKHYST---------------SVDVWSIGCIFAEMLTRR</Hsp_qseq>
      <Hsp_hseq>YHFFKSFQKKLFLPSVDLDSILQLTENELNRLPHYREIAFQLRVQSHGNIVKIHQVLESSIATFIVMDYYDRDLFTSIVDDKHFVNH----GI---LIKKVFLQLCSALDHCHRLGIYHCDIKPENVLLDRNDNAYLCDFGLSTKSKYLAPNVC----VGSSYYMAPERILYCLNTTTNGIHVDECCSSLPTDTGDIWSLGIILINLTCIR</Hsp_hseq>
      <Hsp_midline>Y      + KL   +V L  I   TE E       REI+  LR  +H NIV++  ++ S    ++V +  D+DL       K F+++    GI   L+K    QL   +  CH   I H D+KP+N+L++      L DFGL+    +  P       V + +Y APE +L C + +T               + D+WS+G I   +   R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>91</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>9.86175e-11</Hsp_evalue>
      <Hsp_query-from>276</Hsp_query-from>
      <Hsp_query-to>926</Hsp_query-to>
      <Hsp_hit-from>118</Hsp_hit-from>
      <Hsp_hit-to>370</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>52</Hsp_gaps>
      <Hsp_align-len>261</Hsp_align-len>
      <Hsp_qseq>MDNFQKVEKIGEGTYGVVYKARNKLTGEA--VALKKIRLDTETEGVPSTAI----------------REISL--LRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINA------EGAI------------------KLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFR</Hsp_qseq>
      <Hsp_hseq>LHNYKLLNKIGEGAFSRVFKAVGINTDDQAPVAIKAII----KKGISSDAILKGNDRIQGSSRKKVLNEVAIHKLVSKNNPHCTKFIAFQESANYYYLVTELVTGG-EIFDRIVQLTCFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKK--LRNNTAKTPCGTIEYVASEVFTS-KRYSMKVDMWSIGCVLFTLLCGYPPFYEKNEKTLLKKISR</Hsp_hseq>
      <Hsp_midline>+ N++ + KIGEG +  V+KA    T +   VA+K I      +G+ S AI                 E+++  L   N+P+  + +    S    YLV EL+    + F      +     L +  + Q+   I   H   I+HRD+KP+NLL         +G +                  KL DFGLA+   +   T      T+ Y A E+    K YS  VD+WSIGC+   +L     F   +E   L +I R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>92</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>5.35825e-10</Hsp_evalue>
      <Hsp_query-from>282</Hsp_query-from>
      <Hsp_query-to>902</Hsp_query-to>
      <Hsp_hit-from>840</Hsp_hit-from>
      <Hsp_hit-to>1055</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>228</Hsp_align-len>
      <Hsp_qseq>NFQKVEKIGEGTYGVVYKARNKLTGEAVALK-----KIRLDT----ETEGVPSTAIREISLLRELNHPNIVRLL------------TIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEI</Hsp_qseq>
      <Hsp_hseq>DFTILQVMGEGAYGKVNLCIHNREHYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKNSQENILKLLDFFEDDDYYYIETPVHGETGSIDLFDVIE--FKKDMVEHE--------AKLVFKQVVASIKHLHDQGIVHRDIKDENVIVDSHGFVKLIDFG--SAAYIKSGPFDVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLYTIIYKENPYYNIDEI</Hsp_hseq>
      <Hsp_midline>+F  ++ +GEG YG V    +      V +K     +I +DT       G   + I+ ++ L + +  NI++LL            T +H E     +F++++   KK M             K    Q++  I   H   I+HRD+K +N+++++ G +KL DFG   A  +    +   V T+ Y APE+L G  +     D+W++G +   ++ +   +    EI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>93</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>5.75732e-10</Hsp_evalue>
      <Hsp_query-from>279</Hsp_query-from>
      <Hsp_query-to>731</Hsp_query-to>
      <Hsp_hit-from>350</Hsp_hit-from>
      <Hsp_hit-to>500</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>163</Hsp_align-len>
      <Hsp_qseq>DNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLREL----NHPNIVRLLTIIHSEKKLYLVFELL-DQDL-------KKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAF</Hsp_qseq>
      <Hsp_hseq>EDFHTVKVIGKGAFGEVRLVQKKDTGKIYAMKTL---LKSEMYKKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVT---------RFYMAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGF</Hsp_hseq>
      <Hsp_midline>++F  V+ IG+G +G V   + K TG+  A+K +    ++E      +  +   R++    + P +V L       + LYL+ E L   DL       + F ++ T         + Y+ + +  I   H    +HRD+KP N+LI+  G IKL+DFGL+  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>94</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>5.75786e-10</Hsp_evalue>
      <Hsp_query-from>276</Hsp_query-from>
      <Hsp_query-to>863</Hsp_query-to>
      <Hsp_hit-from>441</Hsp_hit-from>
      <Hsp_hit-to>646</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>210</Hsp_align-len>
      <Hsp_qseq>MDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNH---------PNIVRLLTIIHSEKKLYLVFELLDQ-DLKKFMDN---ATPSGIPLPLVKSYLYQLLQGIAFCH-SHRILHRDLKPQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEM</Hsp_qseq>
      <Hsp_hseq>FEKFTNVHSIGKGQFSTVYQVTFAQTNKKYAIKAIKPNKYNSL--KRILLEIKILNEVTNQITMDQEGKEYIIDYISSWKFQNSYYIMTELCENGNLDGFLQEQVIAKKKRLEDWRIWKIIVELSLALRFIHDSCHIVHLDLKPANVMITFEGNLKLGDFGMATHLPLEDKSFENE-GDREYIAPEIISDCT-YDYKADIFSLGLMIVEI</Hsp_hseq>
      <Hsp_midline> + F  V  IG+G +  VY+     T +  A+K I+ +          + EI +L E+ +           I+  ++    +   Y++ EL +  +L  F+     A    +    +   + +L   + F H S  I+H DLKP N++I  EG +KL DFG+A    +  +++ +E     Y APEI+  C  Y    D++S+G +  E+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>95</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>2.24566e-09</Hsp_evalue>
      <Hsp_query-from>285</Hsp_query-from>
      <Hsp_query-to>884</Hsp_query-to>
      <Hsp_hit-from>192</Hsp_hit-from>
      <Hsp_hit-to>445</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>56</Hsp_gaps>
      <Hsp_align-len>255</Hsp_align-len>
      <Hsp_qseq>FQKVEKIGEGTYGVV--YKARNKLTGE--AVALKKIRLDTETEGVP----------------STAIREISLLRELNHPNIVRLLTI-----IHSEKKLYLVFELLDQDLK--KFMDNATPSGIPLP------------LVKSYLYQLLQGIAFCHSHRILHRDLKPQNLL-------INA---------EGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALF</Hsp_qseq>
      <Hsp_hseq>WKKVRPIGSGNFSTVLLYELMDQSNPKLKQVAVKRLKYPEELSNVEQINTSLRYKETLSRLENSLTRELQVLKSLNHPCIVKLLGINNPIFVTSKKPLCDLIIKTPRALPPCDMIMSYCPAGDLLAAVMARNGRLEAWLIQRIFTEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLCKKIEN-NEMCTARCGSEDYVSPEILMGVPYDGHLSDTWALGVILYSLFEDRLPF</Hsp_hseq>
      <Hsp_midline>++KV  IG G +  V  Y+  ++   +   VA+K+++   E   V                 ++  RE+ +L+ LNHP IV+LL I     + S+K L  +     + L     + +  P+G  L             L++    +++  + + H + I+HRDLK +N+L       IN+         +  I+LADFGL +         T    +  Y +PEIL+G  +     D W++G I   +   R  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>96</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>8.60518e-09</Hsp_evalue>
      <Hsp_query-from>285</Hsp_query-from>
      <Hsp_query-to>911</Hsp_query-to>
      <Hsp_hit-from>163</Hsp_hit-from>
      <Hsp_hit-to>428</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>114</Hsp_positive>
      <Hsp_gaps>71</Hsp_gaps>
      <Hsp_align-len>273</Hsp_align-len>
      <Hsp_qseq>FQKVEKIGEGTYGVVYKA---RNK----LTG--EAVALKKIRL-----------------DTETEGVPSTAIREISLLRELNH--PNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLIN---------------------AEGAI-------------KLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPG--DSEIDQL</Hsp_qseq>
      <Hsp_hseq>YKLINKIGEGAFSKVFRAIPAKNSSNEFLTKNYKAVAIKVIKKADLSSINGDHRKKDKGKDSTKTSSRDQVLKEVALHKTVSAGCSQIVAFIDFQETDSYYYIIQELLTGG-EIFGEIVRLTYFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQ--IFSKNTKTPCGTVGYTAPEVVKD-EHYSMKVDMWGIGCVLYTMLCG---FPPFYDEKIDTL</Hsp_hseq>
      <Hsp_midline>++ + KIGEG +  V++A   +N     LT   +AVA+K I+                  D+         ++E++L + ++     IV  +    ++   Y++ ELL    + F +    +     L +  + QL   +   HS  ++HRD+KP+NLL                       A+  I             KLADFGL++   +  +       T+ Y APE++   +HYS  VD+W IGC+   ML     FP   D +ID L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>97</Hit_num>
  <Hit_id>YMR291W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:852630:854390:1 gene:YMR291W transcript:YMR291W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TDA1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000004905]</Hit_def>
  <Hit_accession>YMR291W</Hit_accession>
  <Hit_len>586</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>1.27211e-08</Hsp_evalue>
      <Hsp_query-from>303</Hsp_query-from>
      <Hsp_query-to>851</Hsp_query-to>
      <Hsp_hit-from>45</Hsp_hit-from>
      <Hsp_hit-to>281</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>68</Hsp_gaps>
      <Hsp_align-len>244</Hsp_align-len>
      <Hsp_qseq>IGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELN-------------------HPNIVRLLTIIHSEKKLYLVFELLDQ-DL-KKFMDNATPSGIPLPL---VKSYLYQLLQGIAFCHSHRILHRDLKPQNLLI---------NAEGA-------------IKLADFGLARAFGVPQRTYTHEVV-TLWYRAPEILLGCK--------------HYSTSVDVWSIGCI</Hsp_qseq>
      <Hsp_hseq>LGDGNFSVVKECMNIHTKDLYAMKLIKKQTVKNKI-QLIQREFDLLRSISEKIRDMEKKNEHSLDIFEGHHHILQLFDYFETADNIVLITQLCQKGDLYEKIVENQC-----LDLETQVTSYCACLVSVLEFLHSQGIVHRDLKAENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLVLADFGLAAEYNTSKVNSLKEFVGTISYIAPEI-VKCKGVGEMTPDQVGKLDKYGCPVDIWALGVL</Hsp_hseq>
      <Hsp_midline>+G+G + VV +  N  T +  A+K I+  T    +     RE  LLR ++                   H +I++L     +   + L+ +L  + DL +K ++N       L L   V SY   L+  + F HS  I+HRDLK +N+L          N +G              + LADFGLA  +   +     E V T+ Y APEI + CK               Y   VD+W++G +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>98</Hit_num>
  <Hit_id>YHR135C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:372694:374310:-1 gene:YHR135C transcript:YHR135C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YCK1 description:Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform; shares redundant functions with Yck2p in morphogenesis, proper septin assembly, endocytic trafficking, and glucose sensing; stabilized by Sod1p binding in the presence of glucose and oxygen, causing glucose repression of respiratory metabolism; involved in the phosphorylation and regulation of glucose sensor Rgt2p; YCK1 has a paralog, YCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001177]</Hit_def>
  <Hit_accession>YHR135C</Hit_accession>
  <Hit_len>538</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>1.32622e-08</Hsp_evalue>
      <Hsp_query-from>297</Hsp_query-from>
      <Hsp_query-to>854</Hsp_query-to>
      <Hsp_hit-from>73</Hsp_hit-from>
      <Hsp_hit-to>265</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>203</Hsp_align-len>
      <Hsp_qseq>EKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNH-PNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGA-----IKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHY-----------STSVDVWSIGCIF</Hsp_qseq>
      <Hsp_hseq>KKIGEGSFGVLFEGTNMINGVPVAIKFEPRKTEAPQLRD----EYKTYKILNGTPNIPYAYYFGQEGLHNILVIDLLGPSLEDLFD-WCGRKFSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANNIHLIDFGMAKQYRDP-KTKQH----IPYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVF</Hsp_hseq>
      <Hsp_midline>+KIGEG++GV+++  N + G  VA+K     TE   +      E    + LN  PNI              LV +LL   L+   D        +  V     Q++  I   H+H +++RD+KP N LI   G      I L DFG+A+ +  P +T  H    + YR  + L G   Y           S   D+ ++G +F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>99</Hit_num>
  <Hit_id>YMR216C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:698811:701039:-1 gene:YMR216C transcript:YMR216C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKY1 description:SR protein kinase (SRPK); involved in regulating proteins involved in mRNA metabolism and cation homeostasis; similar to human SRPK1 [Source:SGD;Acc:S000004829]</Hit_def>
  <Hit_accession>YMR216C</Hit_accession>
  <Hit_len>742</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>1.76986e-08</Hsp_evalue>
      <Hsp_query-from>294</Hsp_query-from>
      <Hsp_query-to>710</Hsp_query-to>
      <Hsp_hit-from>161</Hsp_hit-from>
      <Hsp_hit-to>315</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>158</Hsp_align-len>
      <Hsp_qseq>VEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPN-----------IVRLLTIIHSEK----KLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSH-RILHRDLKPQNLLI---NAEGAIKLAD</Hsp_qseq>
      <Hsp_hseq>VRKLGWGHFSTVWLAKDMVNNTHVAMKIVRGD---KVYTEAAEDEIKLLQRVNDADNTKEDSMGANHILKLLDHFNHKGPNGVHVVMVFEVLGENLLALIKKYEHRGIPLIYVKQISKQLLLGLDYMHRRCGIIHTDIKPENVLMEIGDVEGIVQMVE</Hsp_hseq>
      <Hsp_midline>V K+G G +  V+ A++ +    VA+K +R D   +     A  EI LL+ +N  +           I++LL   + +      + +VFE+L ++L   +      GIPL  VK    QLL G+ + H    I+H D+KP+N+L+   + EG +++ +</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>1.69355e-06</Hsp_evalue>
      <Hsp_query-from>663</Hsp_query-from>
      <Hsp_query-to>935</Hsp_query-to>
      <Hsp_hit-from>540</Hsp_hit-from>
      <Hsp_hit-to>627</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>97</Hsp_align-len>
      <Hsp_qseq>PQNLLINAEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDS------EIDQLFRIFRTLG</Hsp_qseq>
      <Hsp_hseq>PENLI-----QIKIADLGNACWY---DEHYTNSIQTREYRSPEVLLGAP-WGCGADIWSTACLIFELITGDFLFEPDEGHSYTKDDDHIAQIIELLG</Hsp_hseq>
      <Hsp_midline>P+NL+      IK+AD G A  +      YT+ + T  YR+PE+LLG   +    D+WS  C+  E++T   LF  D       + D + +I   LG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>100</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>1.5437e-07</Hsp_evalue>
      <Hsp_query-from>603</Hsp_query-from>
      <Hsp_query-to>923</Hsp_query-to>
      <Hsp_hit-from>190</Hsp_hit-from>
      <Hsp_hit-to>302</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>116</Hsp_align-len>
      <Hsp_qseq>QLLQGIAFCHSHRILHRDLKPQNLLINA-EGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEIL---LGCKHYS-----TSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIF</Hsp_qseq>
      <Hsp_hseq>QIMDAIEYVHNKGIYHRDIKPENILISGIDWTIKLTDWGLAT---TDKTSMDRNVGSERYMSPELFDSNLDIKERKEPYDCAKVDLWAMGIVFLNIVFHKNPFSIANQSDKSFCYF</Hsp_hseq>
      <Hsp_midline>Q++  I + H+  I HRD+KP+N+LI+  +  IKL D+GLA      + +    V +  Y +PE+    L  K          VD+W++G +F  ++  +  F   ++ D+ F  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>101</Hit_num>
  <Hit_id>YNL154C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:343636:345276:-1 gene:YNL154C transcript:YNL154C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YCK2 description:Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform; shares redundant functions with Yck1p in morphogenesis, proper septin assembly, endocytic trafficking, and glucose sensing; stabilized by Sod1p binding in the presence of glucose and oxygen, causing glucose repression of respiratory metabolism; involved in the phosphorylation and regulation of glucose sensor Rgt2p; YCK2 has a paralog, YCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005098]</Hit_def>
  <Hit_accession>YNL154C</Hit_accession>
  <Hit_len>546</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>1.65314e-07</Hsp_evalue>
      <Hsp_query-from>297</Hsp_query-from>
      <Hsp_query-to>854</Hsp_query-to>
      <Hsp_hit-from>80</Hsp_hit-from>
      <Hsp_hit-to>272</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>202</Hsp_align-len>
      <Hsp_qseq>EKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEG-----AIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHY-----------STSVDVWSIGCIF</Hsp_qseq>
      <Hsp_hseq>KKIGEGSFGVLFEGTNMINGLPVAIKFEPRKTEAPQL-KDEYRTYKILAGT--PGIPQEYYFGQEGLHNILVIDLLGPSLEDLFD-WCGRRFSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANKVHLIDFGMAKQYRDP-KTKQH----IPYREKKSLSGTARYMSINTHLGREQSRRDDMEAMGHVF</Hsp_hseq>
      <Hsp_midline>+KIGEG++GV+++  N + G  VA+K     TE   +     R   +L     P I +            LV +LL   L+   D        +  V     Q++  I   H+H +++RD+KP N LI   G      + L DFG+A+ +  P +T  H    + YR  + L G   Y           S   D+ ++G +F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>102</Hit_num>
  <Hit_id>YKL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:347214:349136:-1 gene:YKL048C transcript:YKL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ELM1 description:Serine/threonine protein kinase; regulates the orientation checkpoint, the morphogenesis checkpoint and the metabolic switch from fermentative to oxidative metabolism by phosphorylating the activation loop of Kin4p, Hsl1p and Snf4p respectively; cooperates with Hsl7p in recruiting Hsl1p to the septin ring, a prerequisite for subsequent recruitment, phosphorylation, and degradation of Swe1p; forms part of the bud neck ring; regulates cytokinesis [Source:SGD;Acc:S000001531]</Hit_def>
  <Hit_accession>YKL048C</Hit_accession>
  <Hit_len>640</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>1.27181e-06</Hsp_evalue>
      <Hsp_query-from>582</Hsp_query-from>
      <Hsp_query-to>923</Hsp_query-to>
      <Hsp_hit-from>235</Hsp_hit-from>
      <Hsp_hit-to>367</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>133</Hsp_align-len>
      <Hsp_qseq>LVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAI-KLADFG--LARAFGVP----------QRTYTHEVVTLWYRAPEIL-LGC--KHYSTS---VDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIF</Hsp_qseq>
      <Hsp_hseq>FAKKILEDMTKGLEYLHSQGCIHRDIKPSNILLDEEEKVAKLSDFGSCIFTPQSLPFSDANFEDCFQRELNKIVGTPAFIAPELCHLGNSKRDFVTDGFKLDIWSLGVTLYCLLYNELPFFGENEFETYHKII</Hsp_hseq>
      <Hsp_midline>  K  L  + +G+ + HS   +HRD+KP N+L++ E  + KL+DFG  +     +P          QR     V T  + APE+  LG   + + T    +D+WS+G     +L     F G++E +   +I </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>103</Hit_num>
  <Hit_id>YBR059C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:356861:360187:-1 gene:YBR059C transcript:YBR059C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AKL1 description:Ser-Thr protein kinase; member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization [Source:SGD;Acc:S000000263]</Hit_def>
  <Hit_accession>YBR059C</Hit_accession>
  <Hit_len>1108</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>2.2102e-06</Hsp_evalue>
      <Hsp_query-from>354</Hsp_query-from>
      <Hsp_query-to>866</Hsp_query-to>
      <Hsp_hit-from>72</Hsp_hit-from>
      <Hsp_hit-to>262</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>195</Hsp_align-len>
      <Hsp_qseq>GEAVALKKIRLDTETEGVPSTAIREISLLRELN-HPNIVRLLTIIHSEKK-------LYLVFELL-DQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCH--SHRILHRDLKPQNLLINAEGAIKLADFG-LARAFGV----------PQRTYTHEVVTLWYRAPEI--LLGCKHYSTSVDVWSIGCIFAEML</Hsp_qseq>
      <Hsp_hseq>GDVACLKRVLVQDEN-GL-NEMRNEVEVMKKLKGAPNIVQYFDSNASRRRDGVQGFEVLLLMELCPNKSLLDYMNQRLSTKLTEAEIVKIMYDVALSISQMHYLPVSLIHRDIKIENVLVDAKNNFKLADFGSTSTCFPIVTTHQDIALLTQNIYVH--TTPQYRSPEMIDLYRCLPINEKSDIWALGVFLYKLL</Hsp_hseq>
      <Hsp_midline>G+   LK++ +  E  G+ +    E+ ++++L   PNIV+      S ++       + L+ EL  ++ L  +M+    + +    +   +Y +   I+  H     ++HRD+K +N+L++A+   KLADFG  +  F +           Q  Y H   T  YR+PE+  L  C   +   D+W++G    ++L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1320390393</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0041376-RA transcript Note:&quot;Similar to Kcnh8 Potassium voltage-gated channel subfamily H member 8 (Rattus norvegicus)&quot; offset:0 AED:0.18 eAED:0.18 QI:0|0|0|0.5|1|1|2|0|73</Iteration_query-def>
  <Iteration_query-len>222</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>46</Statistics_hsp-len>
      <Statistics_eff-space>73093076</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0051948-RA transcript Note:&quot;Similar to Kcnh8 Potassium voltage-gated channel subfamily H member 8 (Rattus norvegicus)&quot; offset:0 AED:0.41 eAED:0.41 QI:0|0|0|0.28|1|1|7|0|645</Iteration_query-def>
  <Iteration_query-len>1938</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1254256850</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0051949-RA transcript Note:&quot;Similar to KCNH8 Potassium voltage-gated channel subfamily H member 8 (Homo sapiens)&quot; offset:0 AED:0.64 eAED:0.64 QI:0|0.16|0|0.85|1|1|7|0|571</Iteration_query-def>
  <Iteration_query-len>1716</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1090930959</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0051951-RA transcript Note:&quot;Similar to Agap1 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (Mus musculus)&quot; offset:0 AED:0.10 eAED:0.10 QI:0|0.71|0.87|0.87|0.57|0.62|8|859|279</Iteration_query-def>
  <Iteration_query-len>1699</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YML001W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:267174:267800:1 gene:YML001W transcript:YML001W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPT7 description:Rab family GTPase; GTP-binding protein of the rab family; required for homotypic fusion event in vacuole inheritance, for endosome-endosome fusion; localizes to sites of contact between the vacuole and mitochondria (vCLAMPs); interacts with the cargo selection/retromer complex for retrograde sorting; similar to mammalian Rab7 [Source:SGD;Acc:S000004460]</Hit_def>
  <Hit_accession>YML001W</Hit_accession>
  <Hit_len>208</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>1.25883e-06</Hsp_evalue>
      <Hsp_query-from>34</Hsp_query-from>
      <Hsp_query-to>375</Hsp_query-to>
      <Hsp_hit-from>3</Hsp_hit-from>
      <Hsp_hit-to>127</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>125</Hsp_align-len>
      <Hsp_qseq>SRAVPELKVGIVGNLASGKSALVHRYLTGAYMQE-ESPEGGRF-KKEIVVDGQSYLLL-IRDEGGPPEPQ-----FASWVDATIFVFSLEDEISFQTVYNYYSRL---ANVRNIADLPLLLVGTQ</Hsp_qseq>
      <Hsp_hseq>SRKKNILKVIILGDSGVGKTSLMHRYVNDKYSQQYKATIGADFLTKEVTVDGDKVATMQVWDTAGQERFQSLGVAFYRGADCCVLVYDVTNASSFENIKSWRDEFLVHANVNSPETFPFVILGNK</Hsp_hseq>
      <Hsp_midline>SR    LKV I+G+   GK++L+HRY+   Y Q+ ++  G  F  KE+ VDG     + + D  G    Q     F    D  + V+ + +  SF+ + ++       ANV +    P +++G +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1077208557</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0051952-RA transcript Note:&quot;Similar to Agap1 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (Mus musculus)&quot; offset:0 AED:0.35 eAED:0.35 QI:0|0|0|1|1|1|5|0|309</Iteration_query-def>
  <Iteration_query-len>930</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>89</Statistics_hsp-len>
      <Statistics_eff-space>514193407</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0051953-RA transcript Note:&quot;Similar to AGAP3 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 (Homo sapiens)&quot; offset:0 AED:0.49 eAED:0.49 QI:0|0|0|1|1|1|3|0|208</Iteration_query-def>
  <Iteration_query-len>627</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>85</Statistics_hsp-len>
      <Statistics_eff-space>291780308</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0041377-RA transcript Note:&quot;Protein of unknown function&quot; offset:986 AED:1.00 eAED:1.00 QI:986|0|0|0|0.4|0.5|6|0|216</Iteration_query-def>
  <Iteration_query-len>1637</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>1034443817</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0028984-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.58 eAED:1.00 QI:0|0|0|0.14|0.33|0.28|7|700|531</Iteration_query-def>
  <Iteration_query-len>2296</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1518943156</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0051943-RA transcript Note:&quot;Similar to SLC4A1 Band 3 anion transport protein (Homo sapiens)&quot; offset:0 AED:0.16 eAED:0.18 QI:0|0|0|0.93|0.92|0.93|15|0|841</Iteration_query-def>
  <Iteration_query-len>2526</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YNL275W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:119268:120998:1 gene:YNL275W transcript:YNL275W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BOR1 description:Boron efflux transporter of the plasma membrane; binds HCO3-, I-, Br-, NO3- and Cl-; has similarity to the characterized boron efflux transporter A. thaliana BOR1 [Source:SGD;Acc:S000005219]</Hit_def>
  <Hit_accession>YNL275W</Hit_accession>
  <Hit_len>576</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.1225</Hsp_bit-score>
      <Hsp_score>222</Hsp_score>
      <Hsp_evalue>3.55092e-19</Hsp_evalue>
      <Hsp_query-from>997</Hsp_query-from>
      <Hsp_query-to>2466</Hsp_query-to>
      <Hsp_hit-from>109</Hsp_hit-from>
      <Hsp_hit-to>553</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>120</Hsp_identity>
      <Hsp_positive>210</Hsp_positive>
      <Hsp_gaps>75</Hsp_gaps>
      <Hsp_align-len>505</Hsp_align-len>
      <Hsp_qseq>EKTQGLIGVSELIISTSIQSIFFALLSAQPLLIVGFSGPLLVFEEAFFSFCWSQDVEYLTGRLWIGFWLILIVLLTVAFEGSFLVRYISRFTQEXXXXXXXXXXXYETFYKLFKVFKEHPLLKTYTIGGTDLAGSGVWGNASMVIGSATAAARNDTDAPTKMPSQPNTSLLSLVLMS-GTFFIAFFLRKLKNSRFLAGKVRRVIGDFGVPIAILI---MVLVDSAIPDTYTQKLAVPDGFSVTSP---DQRSWLV-NPLGVRSTFPVWMMFACVVPAALVF-ILIFMETQITTLIVSKSERRLVKGSGFHLDLLLIVLMGGASALLGVPWLTAATVRSVTHVNALTVMSKATAPGEKPRIECVKEQRATGLLVAVLI------GLSVVLGEVLRRIPLAVLFGIFLYMGVTSVNGIQMYDRLLLAFMPAKHHPDSAYASKVKTWRMNMYTAIQFVCLALLWVVMSTAASLAFPFVLILTVPLRHFLLPRIFTAHELRCLDSADAE</Hsp_qseq>
      <Hsp_hseq>DRTDNSYGVNEVLLSSAMAGIVFGVLGGQPLCIVGVTGPISIFNYTVYEIIKPLNTSYFGFMFWICMWSMIFHLVLAFTNAVCLLQYVTTFPCDIFGLFINVVYIQKGIQILTRQF------------------SAKSGEKSVQDGFASV-------------------VVALVMTAFGLFFKLFHYYPLFSHR-----IRTFISDYSTALSVLFWSSFTHFGGYLHDVKFKKLPITKAFFPTSKVNRPQNTWLAYEPIPVKDVF-------IALPFGIFLTILFYFDHNVSSLMAQRHQYKLKKPSSFHYDFALLGLTTCISGVLGIPAPNGLIPQAPLHTETLLVRDS-----NQKVISCV-EQRFTNTFQGLMILGTMTRPLLVCLGE----IPQAVLSGLFFIMGINGLMTNSIIQRLVFLFSDPNRRDNTSPLMKVSKKSMLIFLSFSLTGFAGEFAITNTIAAIG-FPLVLLLSVLVSFSFAYIFPTEELKILDTNVAQ</Hsp_hseq>
      <Hsp_midline>++T    GV+E+++S+++  I F +L  QPL IVG +GP+ +F    +      +  Y     WI  W ++  L+        L++Y++ F  +IF + I++++I +    L + F                  S   G  S+  G A+                    +++LV+ + G FF  F    L + R     +R  I D+   +++L           + D   +KL +   F  TS     Q +WL   P+ V+  F         +P  +   IL + +  +++L+  + + +L K S FH D  L+ L    S +LG+P       ++  H   L V         +  I CV EQR T     ++I       L V LGE    IP AVL G+F  MG+  +    +  RL+  F       +++   KV    M ++ +      A  + + +T A++    +++L   L  F    IF   EL+ LD+  A+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1686846648</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0051944-RA transcript Note:&quot;Similar to RACGAP1 Rac GTPase-activating protein 1 (Homo sapiens)&quot; offset:0 AED:0.21 eAED:0.29 QI:0|0.14|0.5|1|0.42|0.62|8|1752|342</Iteration_query-def>
  <Iteration_query-len>2781</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>1871832276</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0051945-RA transcript Note:&quot;Similar to osgepl1 Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial (Danio rerio)&quot; offset:194 AED:0.11 eAED:0.11 QI:194|0.8|1|1|0.2|0.33|6|1328|319</Iteration_query-def>
  <Iteration_query-len>2482</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDL104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:273653:274876:-1 gene:YDL104C transcript:YDL104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:QRI7 description:Protein involved in threonylcarbamoyl adenosine biosynthesis; Sua5p and Qri7p are necessary and sufficient for RNA t6A modification in vitro; highly conserved mitochondrial protein; essential for t6A modification of mitochondrial tRNAs that decode ANN codons; similar to Kae1p and E. coli YgjD, both of which are also required for tRNA t6A modification; when directed to the cytoplasm, complements the essential function of Kae1p in the KEOPS complex [Source:SGD;Acc:S000002262]</Hit_def>
  <Hit_accession>YDL104C</Hit_accession>
  <Hit_len>407</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.5666</Hsp_bit-score>
      <Hsp_score>192</Hsp_score>
      <Hsp_evalue>9.10501e-16</Hsp_evalue>
      <Hsp_query-from>321</Hsp_query-from>
      <Hsp_query-to>872</Hsp_query-to>
      <Hsp_hit-from>22</Hsp_hit-from>
      <Hsp_hit-to>204</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>189</Hsp_align-len>
      <Hsp_qseq>ASRRPQAVSTGGAPCLVLGLETSCDETGAAVLCARSGALLGEALHSQKEV--HVRNGGIIPTLAQQLHREHIAGVVQEALRASGTSLCHLHAIATSVRPGLALCLAVGLEHSALLLERAGPHAKFIPIHHMEAHALTVRMMQQ---VEFPFLVLLVSGGHCLLAVARGVDDFLRLGQTLDEAPGDIFDK</Hsp_qseq>
      <Hsp_hseq>AFNRPIQLRKGYK---VLAIETSCDDTCVSVLDRFSKSAAPNVLANLKDTLDSIDEGGIIPTKAHIHHQARIGPLTERALIESNARE-GIDLICVTRGPGMPGSLSGGLDFAKGLA--VAWNKPLIGVHHMLGHLLIPRMGTNGKVPQFPFVSLLVSGGHTTFVLSRAIDDHEILCDTIDIAVGDSLDK</Hsp_hseq>
      <Hsp_midline>A  RP  +  G     VL +ETSCD+T  +VL   S +     L + K+    +  GGIIPT A   H+  I  + + AL  S      +  I  +  PG+   L+ GL+ +  L      +   I +HHM  H L  RM       +FPF+ LLVSGGH    ++R +DD   L  T+D A GD  DK</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>1.09412e-06</Hsp_evalue>
      <Hsp_query-from>846</Hsp_query-from>
      <Hsp_query-to>1046</Hsp_query-to>
      <Hsp_hit-from>312</Hsp_hit-from>
      <Hsp_hit-to>387</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>42</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>76</Hsp_align-len>
      <Hsp_qseq>EAPGDIFDKVVSGGVASN----SVIKEALGHVATAVGFTVICPPPHLCTDNGIMIGWNGVE-----RLRANVGILP</Hsp_qseq>
      <Hsp_hseq>EKFKNVREFVCSGGVSSNQRLRTKLETELGTLNSTSFFNFYYPPMDLCSDNSIMIGWAGIEIWESLRLVSDLDICP</Hsp_hseq>
      <Hsp_midline>E   ++ + V SGGV+SN    + ++  LG + +   F    PP  LC+DN IMIGW G+E     RL +++ I P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1652837643</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0026747-RA transcript Note:&quot;Similar to Gpnmb Transmembrane glycoprotein NMB (Rattus norvegicus)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.57|0.5|8|433|279</Iteration_query-def>
  <Iteration_query-len>1273</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>92</Statistics_hsp-len>
      <Statistics_eff-space>765879844</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

