<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0052378-RA transcript Note:&quot;Similar to si:ch211-275j6.5 Probable peptide chain release factor C12orf65 homolog, mitochondrial (Danio rerio)&quot; offset:201 AED:0.04 eAED:0.04 QI:201|1|1|1|1|1|2|1253|172</BlastOutput_query-def>
  <BlastOutput_query-len>1973</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052378-RA transcript Note:&quot;Similar to si:ch211-275j6.5 Probable peptide chain release factor C12orf65 homolog, mitochondrial (Danio rerio)&quot; offset:201 AED:0.04 eAED:0.04 QI:201|1|1|1|1|1|2|1253|172</Iteration_query-def>
  <Iteration_query-len>1973</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YLR281C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:704493:704960:-1 gene:YLR281C transcript:YLR281C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YLR281C is not an essential gene [Source:SGD;Acc:S000004271]</Hit_def>
  <Hit_accession>YLR281C</Hit_accession>
  <Hit_len>155</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>3.52961e-11</Hsp_evalue>
      <Hsp_query-from>421</Hsp_query-from>
      <Hsp_query-to>549</Hsp_query-to>
      <Hsp_hit-from>45</Hsp_hit-from>
      <Hsp_hit-to>87</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>33</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>43</Hsp_align-len>
      <Hsp_qseq>GSGPGGQATNKTSNCVVLKHVPSGIVVKCHQTRSLETNRKLAR</Hsp_qseq>
      <Hsp_hseq>GRGPGGQKINKCNSKVQLRHEPTGIVVECQETRSREQNRKLAR</Hsp_hseq>
      <Hsp_midline>G GPGGQ  NK ++ V L+H P+GIVV+C +TRS E NRKLAR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YGL143C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:234717:235958:-1 gene:YGL143C transcript:YGL143C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRF1 description:Mitochondrial translation release factor; involved in stop codon recognition and hydrolysis of the peptidyl-tRNA bond during mitochondrial translation; lack of MRF1 causes mitochondrial genome instability [Source:SGD;Acc:S000003111]</Hit_def>
  <Hit_accession>YGL143C</Hit_accession>
  <Hit_len>413</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>6.19949e-07</Hsp_evalue>
      <Hsp_query-from>412</Hsp_query-from>
      <Hsp_query-to>570</Hsp_query-to>
      <Hsp_hit-from>278</Hsp_hit-from>
      <Hsp_hit-to>330</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>25</Hsp_identity>
      <Hsp_positive>30</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>53</Hsp_align-len>
      <Hsp_qseq>FVRGSGPGGQATNKTSNCVVLKHVPSGIVVKCHQTRSLETNRKLARGILRGKL</Hsp_qseq>
      <Hsp_hseq>IMRASGKGGQHVNTTDSAVRLTHIPSGIVVSMQDERSQHKNKAKAFTILRARL</Hsp_hseq>
      <Hsp_midline> +R SG GGQ  N T + V L H+PSGIVV     RS   N+  A  ILR +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1279341987</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052265-RA transcript Note:&quot;Similar to Stk36 Serine/threonine-protein kinase 36 (Mus musculus)&quot; offset:146 AED:0.44 eAED:0.44 QI:146|0.66|0.57|0.71|0.33|0.57|7|0|306</Iteration_query-def>
  <Iteration_query-len>1067</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>156.762</Hsp_bit-score>
      <Hsp_score>395</Hsp_score>
      <Hsp_evalue>5.95498e-45</Hsp_evalue>
      <Hsp_query-from>144</Hsp_query-from>
      <Hsp_query-to>896</Hsp_query-to>
      <Hsp_hit-from>66</Hsp_hit-from>
      <Hsp_hit-to>318</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>83</Hsp_identity>
      <Hsp_positive>145</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>257</Hsp_align-len>
      <Hsp_qseq>TMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSD-KELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEG-ELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKDPVKWPKNMSSEFRVD----RIGADYAKEFPEVEVGSRTL</Hsp_qseq>
      <Hsp_hseq>TLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLC---GTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDV-VDLLSKLITADLTRRIGNLQSGSRDI</Hsp_hseq>
      <Hsp_midline>T+  + ++  +G GSFG+V+  R  + G+  A+K + K      K++ +   E  +++ ++HP +++M  +F+  + + +V DY EG ELF +L      P    +  A +++ AL YLH+H I++RD+KP+NILL + G +K+ DFGFA+ +   T  L    GTP Y++PE++  KPY+ + D WS+G ++YE+  G  PFY  +  +    I++  V +P     +  VD     I AD  +    ++ GSR +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>152.91</Hsp_bit-score>
      <Hsp_score>385</Hsp_score>
      <Hsp_evalue>2.5014e-43</Hsp_evalue>
      <Hsp_query-from>144</Hsp_query-from>
      <Hsp_query-to>806</Hsp_query-to>
      <Hsp_hit-from>84</Hsp_hit-from>
      <Hsp_hit-to>303</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>129</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>223</Hsp_align-len>
      <Hsp_qseq>TMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSD-KELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEG-ELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKDPVKWP</Hsp_qseq>
      <Hsp_hseq>SLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLC---GTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFP</Hsp_hseq>
      <Hsp_midline>++  + +L  +G GSFG+V+  R  + G+  ALK + K      K++ +   E  ++  + HP I++M  +F+  ++V +V DY EG ELF +L      P    +  A ++  AL YLHS  I++RD+KP+NILL K G +K+ DFGFA+ +   T  L    GTP Y++PE+V  KPY+ + D WS G ++YE+  G  PFY ++  +    I+   +K+P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>151.754</Hsp_bit-score>
      <Hsp_score>382</Hsp_score>
      <Hsp_evalue>5.75874e-43</Hsp_evalue>
      <Hsp_query-from>144</Hsp_query-from>
      <Hsp_query-to>806</Hsp_query-to>
      <Hsp_hit-from>83</Hsp_hit-from>
      <Hsp_hit-to>302</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>132</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>223</Hsp_align-len>
      <Hsp_qseq>TMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPK-VGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEG-ELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKDPVKWP</Hsp_qseq>
      <Hsp_hseq>SLQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLC---GTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFP</Hsp_hseq>
      <Hsp_midline>+++ + +L  +G GSFG+V+  R R+ G+  A+K + K +    K++ +   E  ++  + HP I++M  +F+  +++ ++ DY EG ELF +L      P    +  A ++  AL YLHS  I++RD+KP+NILL K G +K+ DFGFA+ +   T  L    GTP Y++PE+V  KPY+ + D WS G ++YE+  G  PFY ++  +    I+   +++P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>148.288</Hsp_bit-score>
      <Hsp_score>373</Hsp_score>
      <Hsp_evalue>3.01202e-40</Hsp_evalue>
      <Hsp_query-from>156</Hsp_query-from>
      <Hsp_query-to>818</Hsp_query-to>
      <Hsp_hit-from>55</Hsp_hit-from>
      <Hsp_hit-to>276</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>85</Hsp_identity>
      <Hsp_positive>129</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>YHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPK--VGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDH-TADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKDPVKWPKNMS</Hsp_qseq>
      <Hsp_hseq>YQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGR-IEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFLKTSC-GSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLS</Hsp_hseq>
      <Hsp_midline>Y +++ +GEGSFGKV       TGQ VALK I K  + +SD + R + REI  +R L+HP+I+++ D  ++  E+++V +YA  ELF  +     + E++ R    Q++SA+ Y H H+I+HRD+KP+N+LL +   VK+ DFG +  M+    + TS  G+P Y +PE++  K Y     D+WS G ILY +     PF   SI  L   I       PK +S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>139.043</Hsp_bit-score>
      <Hsp_score>349</Hsp_score>
      <Hsp_evalue>1.15554e-36</Hsp_evalue>
      <Hsp_query-from>153</Hsp_query-from>
      <Hsp_query-to>830</Hsp_query-to>
      <Hsp_hit-from>619</Hsp_hit-from>
      <Hsp_hit-to>845</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>81</Hsp_identity>
      <Hsp_positive>127</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>229</Hsp_align-len>
      <Hsp_qseq>KYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKD---PVKWPKNMSSEFR</Hsp_qseq>
      <Hsp_hseq>KYANLVKIGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKEL--IINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVTHCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPPYLNETPLRALYLIATNGTPKLKEPENLSSSLK</Hsp_hseq>
      <Hsp_midline>KY  L  IG+G+ G VY   +  T   VA+K +    +  KEL  +  EI +M+G +HPNIV  +DS+    ++ V+ +Y EG     +     L E Q+  +  + +S L +LHS  +LHRD+K  NILL   G +KL DFGF   ++   L  T++ GTP +M+PE+V  K Y    D+WS+G ++ E+  G PP+   +  + + LI  +    +K P+N+SS  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>130.183</Hsp_bit-score>
      <Hsp_score>326</Hsp_score>
      <Hsp_evalue>9.87229e-36</Hsp_evalue>
      <Hsp_query-from>153</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>6</Hsp_hit-from>
      <Hsp_hit-to>209</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>205</Hsp_align-len>
      <Hsp_qseq>KYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQILEDD--GNLPE----EQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPE-LVEEKPYDHTADLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>QFKQLEKLGNGTYATVYKGLNKTTGVYVALKEV-KLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLF</Hsp_hseq>
      <Hsp_midline>++  LE +G G++  VYKG  + TG  VALK + K+   +       REI +M+ L+H NIV++ D   T+ ++ +V ++ + +L + ++    GN P       V+    QL+  L + H ++ILHRD+KPQN+L+ K G +KL DFG ARA  I     +S   T  Y +P+ L+  + Y  + D+WS GCIL E+  G P F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>130.954</Hsp_bit-score>
      <Hsp_score>328</Hsp_score>
      <Hsp_evalue>2.05715e-35</Hsp_evalue>
      <Hsp_query-from>198</Hsp_query-from>
      <Hsp_query-to>824</Hsp_query-to>
      <Hsp_hit-from>118</Hsp_hit-from>
      <Hsp_hit-to>327</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>211</Hsp_align-len>
      <Hsp_qseq>VYKGRKRYTGQVVALKFIPKVGRSDKEL-RNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDY-AEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKDPVKWPKNMSSE</Hsp_qseq>
      <Hsp_hseq>VYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWS-IINPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMPSNISQD</Hsp_hseq>
      <Hsp_midline>VY  R R TG + ALK + K       L +  RRE++I   L HPN+ +    F  +K V ++ +Y   GE++++L   G   +    +   Q+ +AL Y+H   I+HRD+KP+NIL+G   V+KL DFG++  ++       ++ GT  Y+SPE+VE + YDHT D W++G + +EL  G PPF           I    +K P N+S +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>134.806</Hsp_bit-score>
      <Hsp_score>338</Hsp_score>
      <Hsp_evalue>2.42638e-35</Hsp_evalue>
      <Hsp_query-from>156</Hsp_query-from>
      <Hsp_query-to>773</Hsp_query-to>
      <Hsp_hit-from>82</Hsp_hit-from>
      <Hsp_hit-to>293</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>120</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>213</Hsp_align-len>
      <Hsp_qseq>YHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVG-RSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYA-EGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHT--ADLWSMGCILYELFVGTPPFYT---NSIFQLV</Hsp_qseq>
      <Hsp_hseq>YHRGHFLGEGGFARCFQI-KDDSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERI</Hsp_hseq>
      <Hsp_midline>YH    +GEG F + ++  K  +G++ A K + K   +S+K  + L  EI I + + HPNIVQ +D FE D  V ++ +    G L ++L+    L E +VR    Q+  A+ Y+HS R++HRD+K  NI       +K+ DFG A  ++  +    +I GTP Y++PE++  K   H+   D+WS+G +LY L +G PPF     N+I++ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>133.65</Hsp_bit-score>
      <Hsp_score>335</Hsp_score>
      <Hsp_evalue>7.02099e-35</Hsp_evalue>
      <Hsp_query-from>108</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>4</Hsp_hit-from>
      <Hsp_hit-to>227</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>83</Hsp_identity>
      <Hsp_positive>125</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>225</Hsp_align-len>
      <Hsp_qseq>SNSQTWEHFWPR-TMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKV--------GRSDKEL-RNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAE-GELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTA-DLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>ANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMA-ALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPF</Hsp_hseq>
      <Hsp_midline>+N++T     P  T+  + + E +G GS GKV   +   TG   A+K I K            D  L  N+ REI IM+ L HPN++ + D +ET+  + ++ +YAE GELF +L D G LPE +      Q++  + Y H+  I+HRD+KP+N+LL     +K+ DFG A A+  +  +L +  G+P Y +PE+V   PY+  A D+WS G IL+ L  G  PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>132.88</Hsp_bit-score>
      <Hsp_score>333</Hsp_score>
      <Hsp_evalue>8.34059e-35</Hsp_evalue>
      <Hsp_query-from>138</Hsp_query-from>
      <Hsp_query-to>845</Hsp_query-to>
      <Hsp_hit-from>341</Hsp_hit-from>
      <Hsp_hit-to>578</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>240</Hsp_align-len>
      <Hsp_qseq>PRTMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPK---VGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEG-ELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKDPVKWPKNMSSEFRVDRIG</Hsp_qseq>
      <Hsp_hseq>PLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKS--EVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIG</Hsp_hseq>
      <Hsp_midline>P +++ + +L++IG+GSFGKV + RK+ T +V ALK I K   V +S  E+ +   E  ++  +  P IV +  SF++ +++  V  +  G ELF  L+ +G     + R    +L+ AL  LH   +++RD+KP+NILL   G + LCDFG  +    +     +  GTP Y++PEL+    Y    D W++G +LYE+  G PP+Y   + ++   I+++P+ +P     + +   IG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>133.265</Hsp_bit-score>
      <Hsp_score>334</Hsp_score>
      <Hsp_evalue>9.32545e-35</Hsp_evalue>
      <Hsp_query-from>129</Hsp_query-from>
      <Hsp_query-to>824</Hsp_query-to>
      <Hsp_hit-from>406</Hsp_hit-from>
      <Hsp_hit-to>638</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>82</Hsp_identity>
      <Hsp_positive>139</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>241</Hsp_align-len>
      <Hsp_qseq>HFWPRTMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPK-VGRSDKELRNLRREIDIM---RGLQHPNIVQMLDSFETDKEVVVVTDY-AEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARA---MSINTLVLTSIKGTPLYMSPE-LVEEKPYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKDPVKWPKNMSSE</Hsp_qseq>
      <Hsp_hseq>HYGPQDFE---VLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFC-----GTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQ</Hsp_hseq>
      <Hsp_midline>H+ P+  E   VL ++G+G+FG+VY+ +K+ T ++ A+K + K V     E+ +   E +I+        P IV +  SF+T  ++ +VTDY + GELF  L+ +G   E++ +    +LV AL +LH + I++RD+KP+NILL   G + LCDFG ++A      NT       GT  Y++PE L++E  Y    D WS+G +++E+  G  PF+  +  ++   I    VK+P+++ S+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>131.724</Hsp_bit-score>
      <Hsp_score>330</Hsp_score>
      <Hsp_evalue>2.28697e-34</Hsp_evalue>
      <Hsp_query-from>138</Hsp_query-from>
      <Hsp_query-to>806</Hsp_query-to>
      <Hsp_hit-from>338</Hsp_hit-from>
      <Hsp_hit-to>562</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>130</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>225</Hsp_align-len>
      <Hsp_qseq>PRTMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDK-ELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEG-ELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKDPVKWP</Hsp_qseq>
      <Hsp_hseq>PLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFP</Hsp_hseq>
      <Hsp_midline>P +++ + +L++IG+GSFGKV + RK+ T ++ ALK + K     K E+ +   E  ++  +  P IV +  SF++ +++ +V  +  G ELF  L+ +G     + R    +L+ AL  LH   +++RD+KP+NILL   G + LCDFG  +    +     +  GTP Y++PE++  + Y  T D W++G +LYE+  G PP+Y  ++  +   I++ P+ +P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>131.724</Hsp_bit-score>
      <Hsp_score>330</Hsp_score>
      <Hsp_evalue>2.89341e-34</Hsp_evalue>
      <Hsp_query-from>156</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>41</Hsp_hit-from>
      <Hsp_hit-to>232</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>199</Hsp_align-len>
      <Hsp_qseq>YHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEG-ELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYD-HTADLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>YKILKQIGEGSFGKVYLALHRPTHRKVCLKT------SDKNDPNIVREVFYHRQFDFPYITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTRECMTKT-TLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPF</Hsp_hseq>
      <Hsp_midline>Y +L+ IGEGSFGKVY    R T + V LK       SDK   N+ RE+   R    P I ++ +   T+ +V +  +Y  G EL+  L     +   +  E+  Q+  A+YY HS   +HRD+K +NILL K G  KL DFGF R     T  L ++ GT +YM+PEL+E + YD    D+WS+G ILY L  G  PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>131.724</Hsp_bit-score>
      <Hsp_score>330</Hsp_score>
      <Hsp_evalue>4.20039e-34</Hsp_evalue>
      <Hsp_query-from>144</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>15</Hsp_hit-from>
      <Hsp_hit-to>231</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>83</Hsp_identity>
      <Hsp_positive>121</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>218</Hsp_align-len>
      <Hsp_qseq>TMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPK-------------VGRS--DKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAE-GELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTA-DLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>TIGPWKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALETEGKLLETSC-GSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPF</Hsp_hseq>
      <Hsp_midline>T+  + + E +G GS GKV   R   TGQ  A+K I K             VG +  D     + REI IM+ L HPN++++ D +ET+ ++ +V +YAE GELF +L + G LPE +      Q++  + Y H+  I+HRD+KP+N+LL     +K+ DFG A   +   L+ TS  G+P Y +PE+V   PY   A D+WS G IL+ L  G  PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>130.183</Hsp_bit-score>
      <Hsp_score>326</Hsp_score>
      <Hsp_evalue>1.12174e-33</Hsp_evalue>
      <Hsp_query-from>168</Hsp_query-from>
      <Hsp_query-to>788</Hsp_query-to>
      <Hsp_hit-from>27</Hsp_hit-from>
      <Hsp_hit-to>234</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>209</Hsp_align-len>
      <Hsp_qseq>EMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGL-QHPNIVQMLDSFETDKEVVVVTDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKP-YDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIK</Hsp_qseq>
      <Hsp_hseq>EVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSD-EVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLRPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIK</Hsp_hseq>
      <Hsp_midline>E+IG G FG VYKG    TG+V A+K +     SD E+ +++REI  +  L Q  NI +   S+  D  + ++ ++  G   + L   G + E+ +  I  +L+ AL  +H   ++HRD+K  N+L+   G VKLCDFG A  ++  +L   ++ GTP +M+PE++ E   YD   D+WS+G   YE+  G PP+      + + LIIK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>127.487</Hsp_bit-score>
      <Hsp_score>319</Hsp_score>
      <Hsp_evalue>2.45375e-33</Hsp_evalue>
      <Hsp_query-from>162</Hsp_query-from>
      <Hsp_query-to>782</Hsp_query-to>
      <Hsp_hit-from>216</Hsp_hit-from>
      <Hsp_hit-to>427</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>118</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>214</Hsp_align-len>
      <Hsp_qseq>VLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSF--ETDKEVVVVTDYAEGELFQ-----ILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLI</Hsp_qseq>
      <Hsp_hseq>TLGILGEGAGGSVAKCRLKNGKKVFALKTINTMNTDPEYQKQIFRELQFNKSFKSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFGVS-GEAVNSLAMT-FTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRFPFESDKITQNVAPI</Hsp_hseq>
      <Hsp_midline> L ++GEG+ G V K R +   +V ALK I  +    +  + + RE+   +  +   IVQ    F  E    + +  +Y  G+  +     +L+  G + E  + +IA  ++  L YLH  +++HRD+KPQNILL + G +KLCDFG +   ++N+L +T   GT  YM+PE ++ +PY  T D+WS+G  L E+  G  PF ++ I Q V+ I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>129.028</Hsp_bit-score>
      <Hsp_score>323</Hsp_score>
      <Hsp_evalue>3.50582e-33</Hsp_evalue>
      <Hsp_query-from>168</Hsp_query-from>
      <Hsp_query-to>830</Hsp_query-to>
      <Hsp_hit-from>85</Hsp_hit-from>
      <Hsp_hit-to>343</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>84</Hsp_identity>
      <Hsp_positive>129</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>260</Hsp_align-len>
      <Hsp_qseq>EMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGR----------------------------SDKELRN--------LRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEG-ELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGG-VVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYD-HTADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKDPVKWPKNMSSEFR</Hsp_qseq>
      <Hsp_hseq>KTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTSC-GSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMPSNLSSEAR</Hsp_hseq>
      <Hsp_midline>+ +G+GS G+V   +   TGQ+ A+K +PK                               + +E  N        + REI IM+ + H N++ + + +E   E+ +V +Y +G ELF  L   G LPE +      Q+V  + Y HS  I HRD+KP+N+LL K    +K+ DFG A     N L+ TS  G+P Y SPE+V  +PY    +D+WS G +L+ L  G  PF  ++I +L+  +     + P N+SSE R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>125.946</Hsp_bit-score>
      <Hsp_score>315</Hsp_score>
      <Hsp_evalue>8.63458e-33</Hsp_evalue>
      <Hsp_query-from>156</Hsp_query-from>
      <Hsp_query-to>866</Hsp_query-to>
      <Hsp_hit-from>18</Hsp_hit-from>
      <Hsp_hit-to>248</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>84</Hsp_identity>
      <Hsp_positive>130</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>243</Hsp_align-len>
      <Hsp_qseq>YHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEG----ELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELV--EEKPYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKDPVKWPKNMSSEFRVDRIGADYAKEF</Hsp_qseq>
      <Hsp_hseq>YSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVV-NLEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNG-LPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIR-STLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPPL---SKYDPMKVMTNLPKRKPPKLQGPF------SDAAKDF</Hsp_hseq>
      <Hsp_midline>Y +   IG G+FG VYK   R T ++VA+K +  +  SD+++  L +EI  +  L+ P I   + +   D  + +V +Y  G    +L +    +G LPEE+V  I  ++   L YLH  R +HRD+K  NILL + G+VKL DFG +  +  +TL   +  GTP +M+PE+V  E   Y+  AD+WS+G   YEL  G PP    S +  + ++   P + P  +   F      +D AK+F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>126.331</Hsp_bit-score>
      <Hsp_score>316</Hsp_score>
      <Hsp_evalue>2.71942e-32</Hsp_evalue>
      <Hsp_query-from>168</Hsp_query-from>
      <Hsp_query-to>788</Hsp_query-to>
      <Hsp_hit-from>1179</Hsp_hit-from>
      <Hsp_hit-to>1391</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>122</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>217</Hsp_align-len>
      <Hsp_qseq>EMIGEGSFGKVYKGRKRYTGQVVALKFI--PKVGRSDKEL----RNLRREIDIMRGLQHPNIVQMLDSFETDKEV--VVVTDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFAR-AMSINTLVLTSIKGTPLYMSPELVEEKP-YDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIK</Hsp_qseq>
      <Hsp_hseq>EMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYL-GFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPW---SNLEVVAAMFK</Hsp_hseq>
      <Hsp_midline>EMIG+GSFG VY      TG+++A+K +  PK    ++ +      LR E+  ++ L H NIVQ L  FE    +  + +   A G +  ++   G   E  ++ +  Q++  L YLHS  ILHRDMK  N+LL + G+ K+ DFG +R +  I +    +++GT  +M+PE+V+ K  Y    D+WS+GCI+ E+F G  P+   S  ++V+ + K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>125.561</Hsp_bit-score>
      <Hsp_score>314</Hsp_score>
      <Hsp_evalue>3.97356e-32</Hsp_evalue>
      <Hsp_query-from>99</Hsp_query-from>
      <Hsp_query-to>806</Hsp_query-to>
      <Hsp_hit-from>5</Hsp_hit-from>
      <Hsp_hit-to>289</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>88</Hsp_identity>
      <Hsp_positive>143</Hsp_positive>
      <Hsp_gaps>51</Hsp_gaps>
      <Hsp_align-len>286</Hsp_align-len>
      <Hsp_qseq>KNSSNSQTWEHFWPRTMEKYHVLEMIGEGSFGKVYKGR-KRYTGQVVALKFIPKVGRSDKEL-RNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDY-AEGELFQIL------------------------EDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILL----------------GKGGV-----VKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIK--DPVKWP</Hsp_qseq>
      <Hsp_hseq>KNKDHTTSVNHNLMASAGNYTAEKEIGKGSFATVYRGHLTSDKSQHVAIKEVSRAKLKNKKLLENLEIEIAILKKIKHPHIVGLIDCERTSTDFYLIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLP-NTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVVFEMCCGTPPFRASNHLELFKKIKRANDVITFP</Hsp_hseq>
      <Hsp_midline>KN  ++ +  H    +   Y   + IG+GSF  VY+G       Q VA+K + +    +K+L  NL  EI I++ ++HP+IV ++D   T  +  ++ +Y A G+L  +L                        E+   L    V     QL SAL +L S  ++HRD+KPQN+LL                G  G+     +K+ DFGFAR +  NT +  ++ G+PLYM+PE++  + Y+  ADLWS+G +++E+  GTPPF  ++  +L   I +  D + +P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>123.25</Hsp_bit-score>
      <Hsp_score>308</Hsp_score>
      <Hsp_evalue>7.49456e-32</Hsp_evalue>
      <Hsp_query-from>150</Hsp_query-from>
      <Hsp_query-to>743</Hsp_query-to>
      <Hsp_hit-from>219</Hsp_hit-from>
      <Hsp_hit-to>421</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>205</Hsp_align-len>
      <Hsp_qseq>EKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKE--VVVVTDYAEGELF-----QILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPP</Hsp_qseq>
      <Hsp_hseq>DRIETLGILGEGAGGSVSKCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQFNRSFQSEYIVRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVS-GEAVNSLA-TTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANGKFP</Hsp_hseq>
      <Hsp_midline>++   L ++GEG+ G V K + +   ++ ALK I  +    +  + + RE+   R  Q   IV+    F  D+   + +  +Y  G         +LE  G + E+ + +IA  ++  L YLH  +++HRD+KPQNILL + G VKLCDFG +   ++N+L  T+  GT  YM+PE ++ +PY  T+D+WS+G  + E+  G  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>124.79</Hsp_bit-score>
      <Hsp_score>312</Hsp_score>
      <Hsp_evalue>9.0694e-32</Hsp_evalue>
      <Hsp_query-from>153</Hsp_query-from>
      <Hsp_query-to>749</Hsp_query-to>
      <Hsp_hit-from>24</Hsp_hit-from>
      <Hsp_hit-to>219</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>201</Hsp_align-len>
      <Hsp_qseq>KYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDY-AEGELFQILEDDGN-LPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFY</Hsp_qseq>
      <Hsp_hseq>QYHLKQVIGRGSYGVVYKAINKHTDQVVAIKEV--VYENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSALTLA---GTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNPPYH</Hsp_hseq>
      <Hsp_midline>+YH+ ++IG GS+G VYK   ++T QVVA+K +  V  +D+EL ++  EI +++ L H NIV+         E+ ++ +Y A G L +++      L E + +    Q +  L YLH   ++HRD+K  NILL     VKL DFG +  ++ + L L    GT  +M+PE++  +     +D+WS+G  + E+    PP++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>122.094</Hsp_bit-score>
      <Hsp_score>305</Hsp_score>
      <Hsp_evalue>1.11589e-31</Hsp_evalue>
      <Hsp_query-from>90</Hsp_query-from>
      <Hsp_query-to>761</Hsp_query-to>
      <Hsp_hit-from>28</Hsp_hit-from>
      <Hsp_hit-to>254</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>121</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>230</Hsp_align-len>
      <Hsp_qseq>APFKNSSNSQTWEHFWPRTMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPK--VGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEG-ELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILL---GKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNSI</Hsp_qseq>
      <Hsp_hseq>AKFINKLSGQP-ESYVNRT--NYIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSPFIAESV</Hsp_hseq>
      <Hsp_midline>A F N  + Q  E +  RT   Y     +G GSFG V + RK  T + VA+K + K  +  ++ +L+ L  E+ I++ L HPNIV   D FE+  +  +VT  A G ELF  +   G   E    EI  Q++ A+ Y+HS  ++HRD+KP+N+L     +   + + DFG A+ +     ++    G+  Y++PE++ +  +    D+WS+G I Y L  G  PF   S+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>122.094</Hsp_bit-score>
      <Hsp_score>305</Hsp_score>
      <Hsp_evalue>1.12483e-31</Hsp_evalue>
      <Hsp_query-from>99</Hsp_query-from>
      <Hsp_query-to>761</Hsp_query-to>
      <Hsp_hit-from>8</Hsp_hit-from>
      <Hsp_hit-to>244</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>124</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>237</Hsp_align-len>
      <Hsp_qseq>KNSSNSQTWE-------HFWPRT---MEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALK-FIPKVGRSDK-ELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEG-ELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILL---GKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNSI</Hsp_qseq>
      <Hsp_hseq>KESSPKQTEEDSEGKMAHVQPASYVNKKKYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAFRAERV</Hsp_hseq>
      <Hsp_midline>K SS  QT E       H  P +    +KY   + +G G+FG V + +   TG+ VA+K  I K  + +K +L  L  E+DI++ L HPNIV   D FE+  +  ++T  A+G ELF  +   G   EE    I  +++SA+ Y+HS  I+HRD+KP+N+L         + + DFG A+ +  +  +L    G+  Y++PE++ +  +    D+WS+G I Y L  G   F    +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>124.02</Hsp_bit-score>
      <Hsp_score>310</Hsp_score>
      <Hsp_evalue>1.4609e-31</Hsp_evalue>
      <Hsp_query-from>168</Hsp_query-from>
      <Hsp_query-to>893</Hsp_query-to>
      <Hsp_hit-from>202</Hsp_hit-from>
      <Hsp_hit-to>455</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>136</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>261</Hsp_align-len>
      <Hsp_qseq>EMIGEGSFGKVYKGRKRYTGQVVALKFIPK---VGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEG-ELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGG--VVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELV-------------EEKPYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKDPVKWPKNMSSEFRVDRIGADYAKEFPEVEVGSRT</Hsp_qseq>
      <Hsp_hseq>EVVGQGAFATVKKAIERTTGKTFAVKIISKRKVIGNMD----GVTRELEVLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQG-NGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGS--YHEGPLKDFRISEEARDFIDSLLQVDPNNRS</Hsp_hseq>
      <Hsp_midline>E++G+G+F  V K  +R TG+  A+K I K   +G  D     + RE+++++ L HP IV++   +E  +   +V ++  G +L   +   G + E+  REI+ Q+++A+ Y+HS  I HRD+KP NIL+ +    +VK+ DFG A+    N   + +  GT  Y++PE++             E   Y    D+WSMGC++Y +  G  PF  ++  QL   I +    + +    +FR+     D+     +V+  +R+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>122.479</Hsp_bit-score>
      <Hsp_score>306</Hsp_score>
      <Hsp_evalue>1.77067e-31</Hsp_evalue>
      <Hsp_query-from>147</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>197</Hsp_hit-from>
      <Hsp_hit-to>421</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>230</Hsp_align-len>
      <Hsp_qseq>MEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALK-FIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSF------ETDKEVVVVTDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGG-------------------VVKLCDFGFARAMS----INTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>FDKYLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLC-----GTPSYVAPEVLTKKGYTSKVDLWSAGVILYVCLCGFPPF</Hsp_hseq>
      <Hsp_midline> +KY + + +G G +  V + + + TGQ VA+K F  +     K+ +  R E +I+  +QHPNIV +LDSF         ++ +V+    +GELF+ +     L +++ + +  QL++ L YLH   I+HRD+KP+NILL                        VK+ DFG A+        NTL      GTP Y++PE++ +K Y    DLWS G ILY    G PPF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>118.242</Hsp_bit-score>
      <Hsp_score>295</Hsp_score>
      <Hsp_evalue>2.61379e-31</Hsp_evalue>
      <Hsp_query-from>147</Hsp_query-from>
      <Hsp_query-to>806</Hsp_query-to>
      <Hsp_hit-from>5</Hsp_hit-from>
      <Hsp_hit-to>237</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>82</Hsp_identity>
      <Hsp_positive>122</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>233</Hsp_align-len>
      <Hsp_qseq>MEKYHVLEMIGEGSFGKVYKGRKRYTGQ---VVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDK-EVVVVTDYAEGELFQILE---DDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPE-LVEEKPYDHTADLWSMGCILYELFVGTPPFYTNS----IFQLVSLI-IKDPVKWP</Hsp_qseq>
      <Hsp_hseq>LANYKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWP</Hsp_hseq>
      <Hsp_midline>+  Y  LE +GEG++G VYK      GQ   VVALK I      +       REI +++ L+  NIV++ D   +D  ++ +V ++ + +L + +E    D  L  + V++   QL   + Y HSHRILHRD+KPQN+L+ K G +KL DFG ARA  +     T    T  Y +PE L+  K Y    D WS+GCI  E+    P F  +S    IF++  ++   +   WP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>120.939</Hsp_bit-score>
      <Hsp_score>302</Hsp_score>
      <Hsp_evalue>7.23905e-31</Hsp_evalue>
      <Hsp_query-from>111</Hsp_query-from>
      <Hsp_query-to>809</Hsp_query-to>
      <Hsp_hit-from>113</Hsp_hit-from>
      <Hsp_hit-to>382</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>136</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>271</Hsp_align-len>
      <Hsp_qseq>NSQTWEHFWPRTMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKV-----------GRSD----------------KELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAE-GELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLV----------LTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKDPVKWPK</Hsp_qseq>
      <Hsp_hseq>SSNIGENELSRNLHDFKPVRVLGQGAYGKVLLVKDVNTSKLYAMKQLRKAEILISQTATDSKREDEDKNDGNNNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPP-YTGSNHKVIINKIQQNKQGPK</Hsp_hseq>
      <Hsp_midline>+S   E+   R +  +  + ++G+G++GKV   +   T ++ A+K + K             R D                K L     E  I+  ++HPNIV++  SF  + ++ ++  Y   GELF  L++ G L E  V   A ++  AL +LH+  +++RD+KP+N LL + G + L DFG ++  + ++ V          L SI GTP Y +PE++  K Y    D +S+GC+LY++ VG PP YT S  +++   I+   + PK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>118.627</Hsp_bit-score>
      <Hsp_score>296</Hsp_score>
      <Hsp_evalue>5.31246e-30</Hsp_evalue>
      <Hsp_query-from>141</Hsp_query-from>
      <Hsp_query-to>806</Hsp_query-to>
      <Hsp_hit-from>45</Hsp_hit-from>
      <Hsp_hit-to>296</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>128</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>252</Hsp_align-len>
      <Hsp_qseq>RTMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKV-GRSDKELR------NLRREIDIMRGLQHPNIVQM---LDSFETDKEVVVVTDYAEGELFQILEDDGNLPE--------EQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINT---------LVLTSIKGTPLYMSPELVE-EKPYDHTA--DLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKDPVKWP</Hsp_qseq>
      <Hsp_hseq>QILNNFEILATLGNGQYGKVKLARDLGTGALVAIKILNRFEKRSGYSLQLKVENPRVNQEIEVMKRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPFNANSGLELFDSIINKPLEFP</Hsp_hseq>
      <Hsp_midline>+ +  + +L  +G G +GKV   R   TG +VA+K + +   RS   L+       + +EI++M+   H N+V++   L+  E+ K  +V+   + G +    E+   +          +Q R++   +VS L YLHS  I HRD+KP N+L+   G VK+ DFG A + +  +         L+ +   GTP + +PEL   EK Y  ++  D+WS+G  +Y L  G  PF  NS  +L   II  P+++P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>117.472</Hsp_bit-score>
      <Hsp_score>293</Hsp_score>
      <Hsp_evalue>2.29515e-29</Hsp_evalue>
      <Hsp_query-from>144</Hsp_query-from>
      <Hsp_query-to>806</Hsp_query-to>
      <Hsp_hit-from>37</Hsp_hit-from>
      <Hsp_hit-to>279</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>82</Hsp_identity>
      <Hsp_positive>133</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>245</Hsp_align-len>
      <Hsp_qseq>TMEKYHVLEMIGEGSFGKVYKG-RKRYTG---------QVVALKFIPKVGRSD---KELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYA-EGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAM-SINTLVLTSIKGTPLYMSPELV-EEKPYD-HTADLWSMGCILYELFVGTPPFYTN-------SIFQLVSLIIKDPVKWP</Hsp_qseq>
      <Hsp_hseq>TFGPYILGSTLGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRKEVK-IYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVNEFCSRNELMKTSC-GSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGRLYNYINSTPLKFP</Hsp_hseq>
      <Hsp_midline>T   Y +   +GEG FGKV  G  K ++          + VA+K I +   S+   KE++ + REI+ ++ L HPNIV++ +  +  + + +V +YA  GE ++ ++    L E     +  QL+S ++Y+HS  ++HRD+K +N+LL K   + + DFGF     S N L+ TS  G+P Y +PELV   +PY+   AD+WS G ILY +  G  P+  +        I +L + I   P+K+P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>116.316</Hsp_bit-score>
      <Hsp_score>290</Hsp_score>
      <Hsp_evalue>3.98992e-29</Hsp_evalue>
      <Hsp_query-from>156</Hsp_query-from>
      <Hsp_query-to>782</Hsp_query-to>
      <Hsp_hit-from>360</Hsp_hit-from>
      <Hsp_hit-to>594</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>120</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>237</Hsp_align-len>
      <Hsp_qseq>YHVLEMIGEGSFGKVYKGRK-----------------RYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETD-KEVVVVTDYAEGE-LFQIL---------EDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLI</Hsp_qseq>
      <Hsp_hseq>FQLVEKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQPKKQL--IMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLI</Hsp_hseq>
      <Hsp_midline>+ ++E  G+G+ G VY  ++                 R  G+ VA+K I    +  K+L  +  E+ +M   +  NIV  L+++  D +E+ V+ +Y EG  L  IL         E    L E Q+  I  +    L +LH+ +I+HRD+K  NILL   G+VK+ DFGF   ++       ++ GTP +M+PE+V +K YD   D+WS+G +L E+  G PP+      + + LI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>115.931</Hsp_bit-score>
      <Hsp_score>289</Hsp_score>
      <Hsp_evalue>7.15231e-29</Hsp_evalue>
      <Hsp_query-from>114</Hsp_query-from>
      <Hsp_query-to>842</Hsp_query-to>
      <Hsp_hit-from>165</Hsp_hit-from>
      <Hsp_hit-to>437</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>143</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>277</Hsp_align-len>
      <Hsp_qseq>SQTWEHFWPRTMEKYHVLEMIGEGSFGKVY-----KGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQH-PNIVQMLDSFETDKEVVVVTDYA-EGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLT-----------SIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNS---IFQLV-----------SLIIKDPVK--WPKNMSSEFRVDRI</Hsp_qseq>
      <Hsp_hseq>SKAQKNIIKKGIKDFKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIR----QKKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKVQYAFTPGFPLIIRDLVKKILVKNLDRRLTISQI</Hsp_hseq>
      <Hsp_midline>S+  ++   + ++ +    +IG+G++  V        +KRY  +V+  +++ +     K+++ +  E   ++ L + P++V++  +F+ +  +  + +YA  G+   +++  G+L E   R  A Q++ A+ YLHS+ I+HRD+KP+NILL     +KL DFG A+ ++     ++           S  GT  Y+SPEL+ +   D+  D+W+ GCIL+++  G PPF   +    FQ V            LII+D VK    KN+     + +I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>114.005</Hsp_bit-score>
      <Hsp_score>284</Hsp_score>
      <Hsp_evalue>2.9593e-28</Hsp_evalue>
      <Hsp_query-from>156</Hsp_query-from>
      <Hsp_query-to>830</Hsp_query-to>
      <Hsp_hit-from>546</Hsp_hit-from>
      <Hsp_hit-to>799</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>129</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>256</Hsp_align-len>
      <Hsp_qseq>YHVLEMIGEGSFGKVYKGRKRY-------------------TGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSF-ETDKEVVVVTDYAEG-ELFQILE-----DDGNLP--EEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKD---PVKWPKNMSSEFR</Hsp_qseq>
      <Hsp_hseq>FKVIEKAGQGASGSVYLAERTHIPTESNMIELINNDIDEPHVGDKVAIKQMVLSKQPRKEL--IVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATNGTPKLKHPESLSLEIK</Hsp_hseq>
      <Hsp_midline>+ V+E  G+G+ G VY   + +                    G  VA+K +    +  KEL  +  EI +M+  +H NIV  L+++  TD ++ VV ++ EG  L  I+E     D+ + P  E Q+  I  +    L +LH   I+HRD+K  N+LL     VK+ DFGF   ++       ++ GTP +M+PE+V+++ YD   D+WS+G +  E+  G PP+      + + LI  +    +K P+++S E +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>114.005</Hsp_bit-score>
      <Hsp_score>284</Hsp_score>
      <Hsp_evalue>2.98926e-28</Hsp_evalue>
      <Hsp_query-from>138</Hsp_query-from>
      <Hsp_query-to>806</Hsp_query-to>
      <Hsp_hit-from>321</Hsp_hit-from>
      <Hsp_hit-to>562</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>129</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>247</Hsp_align-len>
      <Hsp_qseq>PRTMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPK---VGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYA-EGELFQILEDDGN--LPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFA--------RAMSINTLVLTSI----------KGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKDPVKWP</Hsp_qseq>
      <Hsp_hseq>PQSFEK---IRLLGQGDVGKVYLVRERDTNQIFALKVLNKHEMIKR--KKIKRVLTEQEILATSDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKFP</Hsp_hseq>
      <Hsp_midline>P++ EK   + ++G+G  GKVY  R+R T Q+ ALK + K   + R  K+++ +  E +I+    HP IV +  SF+T   + +  +Y   GE F+ L+   +  + EE  +  A ++V+AL YLH    ++RD+KP+NILL + G V L DF  +          M  +T + T I           GT  Y++PE++    +    D W++G ++YE+  G  PF  ++  +  S I+   VK+P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>112.464</Hsp_bit-score>
      <Hsp_score>280</Hsp_score>
      <Hsp_evalue>6.43979e-28</Hsp_evalue>
      <Hsp_query-from>141</Hsp_query-from>
      <Hsp_query-to>806</Hsp_query-to>
      <Hsp_hit-from>178</Hsp_hit-from>
      <Hsp_hit-to>406</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>120</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>230</Hsp_align-len>
      <Hsp_qseq>RTMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSF-ETDKEVVVVTDYAEGELFQIL-EDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPE-LVEEKPYDHTADLWSMGCILYELFVGTPPFY-TNSIFQLVSL--IIKDPV--KWP</Hsp_qseq>
      <Hsp_hseq>RSTSVYLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNVSTIKEIMVESQKTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKMNSRADYTNRVI-TLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTPTINSWP</Hsp_hseq>
      <Hsp_midline>R+   Y  +  +GEG++GKVYK +   T ++VALK +   G  +       REI +++   HPN+  + +   E+ K V ++ +YA+ +L  +L   +  +   Q + +  QL+  + YLH ++ILHRD+K  NIL+   G +K+ DFG AR M+        +  T  Y  PE L+    Y    D+W  GC+L ELF  T  F  +N + Q+ S+  I+  P    WP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>110.153</Hsp_bit-score>
      <Hsp_score>274</Hsp_score>
      <Hsp_evalue>7.21686e-28</Hsp_evalue>
      <Hsp_query-from>156</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>13</Hsp_hit-from>
      <Hsp_hit-to>223</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>215</Hsp_align-len>
      <Hsp_qseq>YHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLR--REIDIMRGLQHPNIVQML-----DSFETDKEVVVVTDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTL----------VLTSIKGTPLYMSPE-LVEEKPYDHTADLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>FQLKSLLGEGAYGVVCSATHKPTGEIVAIK---KIEPFDKPLFALRTLREIKILKHFKHENIITIFNIQRPDSFENFNEVYIIQELMQTDLHRVISTQM-LSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIF</Hsp_hseq>
      <Hsp_midline>+ +  ++GEG++G V     + TG++VA+K   K+   DK L  LR  REI I++  +H NI+ +      DSFE   EV ++ +  + +L +++     L ++ ++    Q + A+  LH   ++HRD+KP N+L+     +K+CDFG AR +  +             +T    T  Y +PE ++    Y    D+WS GCIL ELF+  P F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YAR018C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:170396:171703:-1 gene:YAR018C transcript:YAR018C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN3 description:Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol [Source:SGD;Acc:S000000071]</Hit_def>
  <Hit_accession>YAR018C</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>111.309</Hsp_bit-score>
      <Hsp_score>277</Hsp_score>
      <Hsp_evalue>8.28341e-28</Hsp_evalue>
      <Hsp_query-from>96</Hsp_query-from>
      <Hsp_query-to>782</Hsp_query-to>
      <Hsp_hit-from>7</Hsp_hit-from>
      <Hsp_hit-to>300</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>88</Hsp_identity>
      <Hsp_positive>139</Hsp_positive>
      <Hsp_gaps>69</Hsp_gaps>
      <Hsp_align-len>296</Hsp_align-len>
      <Hsp_qseq>FKNSSNSQTWEHFWPRTMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLD-SFETDKEVVVV-TDY-AEGELFQIL----EDDGNLPEEQVREIACQLVSALYYLH---------------------SHRILHRDMKPQNILL-------------------------------GKGG--------VVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLI</Hsp_qseq>
      <Hsp_hseq>FQEYRSPQQQQGHPPRS--EYQVLEEIGRGSFGSVRKVIHIPTKKLLVRKDIKYGHMNSKERQQLIAECSILSQLKHENIVEFYNWDFDEQKEVLYLYMEYCSRGDLSQMIKHYKQEHKYIPEKIVWGILAQLLTALYKCHYGVELPTLTTIYDRMKPPVKGKNIVIHRDLKPGNIFLSYDDSDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLAKSLETSIQFATTYVGTPYYMSPEVLMDQPYSPLSDIWSLGCVIFEMCSLHPPFQAKNYLELQTKI</Hsp_hseq>
      <Hsp_midline>F+   + Q  +   PR+  +Y VLE IG GSFG V K     T +++  K I     + KE + L  E  I+  L+H NIV+  +  F+  KEV+ +  +Y + G+L Q++    ++   +PE+ V  I  QL++ALY  H                      + ++HRD+KP NI L                               GK G        VVKL DFG A+++  +    T+  GTP YMSPE++ ++PY   +D+WS+GC+++E+    PPF   +  +L + I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>112.849</Hsp_bit-score>
      <Hsp_score>281</Hsp_score>
      <Hsp_evalue>8.63107e-28</Hsp_evalue>
      <Hsp_query-from>144</Hsp_query-from>
      <Hsp_query-to>809</Hsp_query-to>
      <Hsp_hit-from>42</Hsp_hit-from>
      <Hsp_hit-to>280</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>126</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>240</Hsp_align-len>
      <Hsp_qseq>TMEKYHVLEMIGEGSFGKVYKGRKRYTG-----QVVALKFIPK---VGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEG-ELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPEL-VEEKPYD-HTADLWSMGCILYELFVGTPPF-------YTNSIFQLVSLIIKDPVKWPK</Hsp_qseq>
      <Hsp_hseq>TFGPYIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIK-IYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARLYKYITQTPLKFPE</Hsp_hseq>
      <Hsp_midline>T   Y +   +GEG FGKV  G  + +      + VA+K I +      +DKE++ + REI+ ++ L HPNI+ + +  +  K + +V ++  G E ++ ++    L E     +  QL+S + Y+H   ++HRD+K +N+LL K   + + DFGF      +  ++ +  G+P Y +PEL V  K Y+   AD+WS G ILY +  G  P+         + I +L   I + P+K+P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>108.997</Hsp_bit-score>
      <Hsp_score>271</Hsp_score>
      <Hsp_evalue>9.11823e-28</Hsp_evalue>
      <Hsp_query-from>174</Hsp_query-from>
      <Hsp_query-to>740</Hsp_query-to>
      <Hsp_hit-from>13</Hsp_hit-from>
      <Hsp_hit-to>203</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>191</Hsp_align-len>
      <Hsp_qseq>IGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQILEDDGNL-PEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELV-EEKPYDHTADLWSMGCILYELFVGTP</Hsp_qseq>
      <Hsp_hseq>VGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNVIELIDIFMAYDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIP</Hsp_hseq>
      <Hsp_midline>+GEG++  VY G +  TG+ +A+K I      D    +  RE+  ++ +QHPN+++++D F     + +V ++   +L  +++D   L     ++      +  +Y+ H + ILHRD+KP N+L    G +K+ DFG ARA+     +LTS   T  Y +PEL+   K Y    D+WS+G I  EL +  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>110.538</Hsp_bit-score>
      <Hsp_score>275</Hsp_score>
      <Hsp_evalue>5.27086e-27</Hsp_evalue>
      <Hsp_query-from>174</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>1040</Hsp_hit-from>
      <Hsp_hit-to>1252</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>213</Hsp_align-len>
      <Hsp_qseq>IGEGSFGKVYKGRKRYTGQVVALKFIP--KVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQILEDDGNLPEEQVREI-ACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAM----------------SINTLVLTSIKGTPLYMSPELVEE---KPYDHTADLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>IGGGTFGQVYSAINLENGEILAVKEIKIHDTTTMKKIFPLIKEEMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEYCEGGSLASLLDHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPW</Hsp_hseq>
      <Hsp_midline>IG G+FG+VY       G+++A+K I         K    ++ E+ ++  L HPNIVQ         +V +  +Y EG     L D G + +E V ++   +L+  L YLH   ++HRD+KP+NILL   G++K  DFG AR +                 + T  L  + GTP+YM+PE +     K      D+W++GC++ E+  G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>109.768</Hsp_bit-score>
      <Hsp_score>273</Hsp_score>
      <Hsp_evalue>9.15551e-27</Hsp_evalue>
      <Hsp_query-from>138</Hsp_query-from>
      <Hsp_query-to>812</Hsp_query-to>
      <Hsp_hit-from>493</Hsp_hit-from>
      <Hsp_hit-to>739</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>133</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>252</Hsp_align-len>
      <Hsp_qseq>PRTMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPK---VGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYA-EGELFQILEDDGN--LPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDF---------------GFARAMSINTLVLT------SIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKDPVKWPKN</Hsp_qseq>
      <Hsp_hseq>PQSFEK---IRLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRN--KIKRVLTEQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKNEVSFPNN</Hsp_hseq>
      <Hsp_midline>P++ EK   + ++G+G  GKV+  R++ T +V ALK + K   + R+  +++ +  E +I+    HP IV +  SF+++  + +  +Y   GE F+ L+      + E+  R  A ++ +AL YLH    ++RD+KP+NILL + G + L DF               G A++  ++T + +      S  GT  Y++PE++    +    D W++G ++YE+  G  PF  ++  +  + I+K+ V +P N</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>106.686</Hsp_bit-score>
      <Hsp_score>265</Hsp_score>
      <Hsp_evalue>1.72778e-26</Hsp_evalue>
      <Hsp_query-from>153</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>12</Hsp_hit-from>
      <Hsp_hit-to>226</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>216</Hsp_align-len>
      <Hsp_qseq>KYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGL-QHPNIVQMLD-----SFETDKEVVVVTDYAEGELFQILEDDGN----LPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAM-----SINTLV--LTSIKGTPLYMSPE-LVEEKPYDHTADLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>QYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRTIR-EIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLF</Hsp_hseq>
      <Hsp_midline>+Y ++++IGEG++G V     + +G  VA+K I    +     R +R EI ++R   +H NI+ +LD     S +    V +V +  E +L +++ +  +    L ++ V+    Q++ AL  +HS +++HRD+KP N+LL     +K+CDFG AR +     S  TLV  +T    T  Y +PE ++  + Y    D+WS GCIL E+  G P F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>105.145</Hsp_bit-score>
      <Hsp_score>261</Hsp_score>
      <Hsp_evalue>6.05693e-26</Hsp_evalue>
      <Hsp_query-from>156</Hsp_query-from>
      <Hsp_query-to>782</Hsp_query-to>
      <Hsp_hit-from>38</Hsp_hit-from>
      <Hsp_hit-to>266</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>234</Hsp_align-len>
      <Hsp_qseq>YHVLEMIGEGSFGKV--YKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQ-HPNIVQMLDSFETDKEVVVVTDY---------AEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLV--------LTSIKGTPLYMSPE-LVEEKPYDHTADLWSMGCILYELFVGTPPFY----TNSIFQLVSLI</Hsp_qseq>
      <Hsp_hseq>YEIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGHKNIVNLIDL-----EIVTSSPYDGLYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVL</Hsp_hseq>
      <Hsp_midline>Y +++ +G+G++G V   K + R     +A+K I  +   +  L+   RE+  M   + H NIV ++D      E+V  + Y          + +L +++     L E  ++    Q++  L Y+HS  ++HRD+KP NIL    G +K+CDFG AR +              +T+   T  Y +PE L+  +PY  + D+W++GCIL E +   P F      + IF+++ ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>107.071</Hsp_bit-score>
      <Hsp_score>266</Hsp_score>
      <Hsp_evalue>6.5196e-26</Hsp_evalue>
      <Hsp_query-from>168</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>15</Hsp_hit-from>
      <Hsp_hit-to>230</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>217</Hsp_align-len>
      <Hsp_qseq>EMIGEGSFGKVYKG------RKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEG-ELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAM-----------------SINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>EELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKV-KYVTIEKNTMNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPF</Hsp_hseq>
      <Hsp_midline>E +G GS+  V+K        K Y  +V + K I K  +  K +   +  ++++    H  I+++  +F  ++ +  V D+A G EL  +L   G   +   R    QL+ AL ++HSH I+HRD+KP+N+LL + G + + DFG A  +                 S +     S  GT  Y+SPEL+      + +D+W++GC++Y+   G PPF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>105.531</Hsp_bit-score>
      <Hsp_score>262</Hsp_score>
      <Hsp_evalue>8.77702e-26</Hsp_evalue>
      <Hsp_query-from>153</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>22</Hsp_hit-from>
      <Hsp_hit-to>217</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>200</Hsp_align-len>
      <Hsp_qseq>KYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKE-VVVVTDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPE-LVEEKPYDHTADLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>RYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLSPLEDIYFVTELQGTDLHRLLQTRP-LEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLAR---IQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLF</Hsp_hseq>
      <Hsp_midline>+Y+ L  +G G+FG V       T Q VA+K I K   +    +   RE+ +++ L+H N++ + D F +  E +  VT+    +L ++L+    L ++ V+    Q++  L Y+HS  ++HRD+KP NIL+ +   +K+CDFG AR   I    +T    T  Y +PE ++  + YD   D+WS GCI  E+  G P F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>106.686</Hsp_bit-score>
      <Hsp_score>265</Hsp_score>
      <Hsp_evalue>1.05617e-25</Hsp_evalue>
      <Hsp_query-from>84</Hsp_query-from>
      <Hsp_query-to>824</Hsp_query-to>
      <Hsp_hit-from>96</Hsp_hit-from>
      <Hsp_hit-to>370</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>136</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>276</Hsp_align-len>
      <Hsp_qseq>TAAPFKNSSNSQTWEHFWPRTMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRS------------------------DKEL-RNLR--REIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEG-ELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDH-TADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKDPVKWPKNMSSE</Hsp_qseq>
      <Hsp_hseq>TTSQSRVSSSQGMPKQFHRKSLGDWEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPPPKNEQDVLERQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIYD-SRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKIKQGKVEYPQHLSIE</Hsp_hseq>
      <Hsp_midline>T +  + SS+    + F  +++  +  +E +G GS GKV   + RYT +V A+K + +  ++                        +KE+ R+ R  RE  + + L HP+I ++ +         ++ +Y  G +L   +   G++ E Q R+ A  + SAL YLH++ I+HRD+K +NI++     +K+ DFG +     +   L +  G+  + +PEL++  PY     D+WS G +L+ L  G  PF   +   L   I +  V++P+++S E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>106.301</Hsp_bit-score>
      <Hsp_score>264</Hsp_score>
      <Hsp_evalue>1.62955e-25</Hsp_evalue>
      <Hsp_query-from>129</Hsp_query-from>
      <Hsp_query-to>824</Hsp_query-to>
      <Hsp_hit-from>90</Hsp_hit-from>
      <Hsp_hit-to>349</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>125</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>261</Hsp_align-len>
      <Hsp_qseq>HFWPRTMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRS------------------------DKEL-RNLR--REIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEG-ELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHT-ADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKDPVKWPKNMSSE</Hsp_qseq>
      <Hsp_hseq>QFHRRSLGDWEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESEILERQKRLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYRKQ-LHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYPSHLSIE</Hsp_hseq>
      <Hsp_midline> F  R++  +  LE +G GS GKV   + R T ++  +K + +  ++                        +KE+ R+ R  RE  + + L HP+I ++ +         ++ +Y  G +L   +   G+L E   R+ A  + SAL YLH++ I+HRD+K +NI++   G +K+ DFG +         L +  G+  + +PEL++ +PY     D+WS G +LY L  G  PF   +   L   I K  V +P ++S E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>105.916</Hsp_bit-score>
      <Hsp_score>263</Hsp_score>
      <Hsp_evalue>1.78639e-25</Hsp_evalue>
      <Hsp_query-from>141</Hsp_query-from>
      <Hsp_query-to>806</Hsp_query-to>
      <Hsp_hit-from>128</Hsp_hit-from>
      <Hsp_hit-to>399</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>128</Hsp_positive>
      <Hsp_gaps>58</Hsp_gaps>
      <Hsp_align-len>276</Hsp_align-len>
      <Hsp_qseq>RTMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFI----------------PKVGRSDKELRNLRREIDIMRGLQHPNIVQM---LDSFETDKEVVVVTDYAEGELF----QILEDDGNLPE----EQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIK----------GTPLYMSPE------------LVEEKPYDHTA-----DLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKDPVKWP</Hsp_qseq>
      <Hsp_hseq>KVLNTYEIIKELGHGQHGKVKLARDILSKQLVAIKIVDRHEKKQRKFFTFIKSSKISENDK----IKREIAIMKKCHHKHVVQLIEVLDDLKSRKIYLVLEYCSRGEVKWCPPDCMESDAKGPSLLSFQETREILRGVVLGLEYLHYQGIIHRDIKPANLLISGDGTVKISDFGVSLAASSTNSSDSSESLDELELAKTVGTPAFFAPEMCLGEDAFTRYNLTKENLFRGSCISFMIDIWAVGVTLYCLLFGMLPFFSDFELKLFEKIVNDPLKFP</Hsp_hseq>
      <Hsp_midline>+ +  Y +++ +G G  GKV   R   + Q+VA+K +                 K+  +DK    ++REI IM+   H ++VQ+   LD  ++ K  +V+   + GE+       +E D   P     ++ REI   +V  L YLH   I+HRD+KP N+L+   G VK+ DFG + A S      +S            GTP + +PE            L +E  +  +      D+W++G  LY L  G  PF+++   +L   I+ DP+K+P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>105.145</Hsp_bit-score>
      <Hsp_score>261</Hsp_score>
      <Hsp_evalue>3.57666e-25</Hsp_evalue>
      <Hsp_query-from>153</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>1265</Hsp_hit-from>
      <Hsp_hit-to>1500</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>236</Hsp_align-len>
      <Hsp_qseq>KYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIP-KVGRSDKELRNL-RREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQILEDDGNLPEEQVREI-ACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIK--------------------------------GTPLYMSPELV---EEKPYDHTADLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>RWQKRNFIGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAALLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPW</Hsp_hseq>
      <Hsp_midline>++     IG G+FG+VY       G+++A+K I  +  +S +++  L + E+ ++  L HPNIV          +V +  +Y EG     L + G + +E V ++   QL+  L YLH   I+HRD+KP+NILL   GV+K  DFG A+ ++ N   L S+                                 GTP+YM+PE +     K      D+WS+GC++ E+  G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>104.76</Hsp_bit-score>
      <Hsp_score>260</Hsp_score>
      <Hsp_evalue>4.89671e-25</Hsp_evalue>
      <Hsp_query-from>144</Hsp_query-from>
      <Hsp_query-to>827</Hsp_query-to>
      <Hsp_hit-from>820</Hsp_hit-from>
      <Hsp_hit-to>1051</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>232</Hsp_align-len>
      <Hsp_qseq>TMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPK---VGRSDKELRNLRREIDIM-RGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKDPVKWPKNMSSEF</Hsp_qseq>
      <Hsp_hseq>SLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDMAGEI</Hsp_hseq>
      <Hsp_midline>+++ + +L+++G+G+FGKV   + + T ++ A+K + K   +   D E     +++ ++    +HP +  +  SF+T+  +    ++  G        +  L   + +  A +++ AL Y H + +++RD+K +NILL   G +K+ D+G  +         ++  GTP +M+PE+++E+ Y    D W+ G +LY++ +   PF  +   ++ + I+ D   +P +M+ E </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>103.605</Hsp_bit-score>
      <Hsp_score>257</Hsp_score>
      <Hsp_evalue>9.46236e-25</Hsp_evalue>
      <Hsp_query-from>126</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>115</Hsp_hit-from>
      <Hsp_hit-to>337</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>223</Hsp_align-len>
      <Hsp_qseq>EHFWPRTMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPK--VGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYA-EGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAM---SINT----------LVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>KHVVKMGIKDFKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQKLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPF</Hsp_hseq>
      <Hsp_midline>+H     ++ +   E +G+GS+  V     R +G+  A+K + K  + R  K       ++ + +      I ++  +F+ +  +  + +YA  G+   +++  G+L E   R  A Q++ A+  LH+  I+HRD+KP+NILL K   VKL DFG A+ +     NT              S  GT  Y+SPEL+ +   D   D+W+ GCILY++  G PPF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>103.605</Hsp_bit-score>
      <Hsp_score>257</Hsp_score>
      <Hsp_evalue>9.63617e-25</Hsp_evalue>
      <Hsp_query-from>174</Hsp_query-from>
      <Hsp_query-to>854</Hsp_query-to>
      <Hsp_hit-from>421</Hsp_hit-from>
      <Hsp_hit-to>697</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>124</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>277</Hsp_align-len>
      <Hsp_qseq>IGEGSFGKVYKGRKRYTGQVVALKFI----------------------------------------PKVGRS--DKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAE-GELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMS-INTLV--LTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPF----YTNSIFQLVSLIIKDPVKWPKNMSSEFRVDRIGADY</Hsp_qseq>
      <Hsp_hseq>IGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKIGTNTTPEIPSWATSEGKNFLRKAFELDY</Hsp_hseq>
      <Hsp_midline>IG GSFG VY G   +TG+++A+K +                                        PK  ++   K +  L+ E+++++ L H NIV    + +    + +  +Y   G +  +L + G   E  +     Q++  + YLH   I+HRD+K  NIL+   G VK+ DFG ++ +S +N       S++G+  +MSPE+V++      AD+WS GC++ E+F G  PF       +IF++ +    +   W  +    F       DY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YDL079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:312951:314748:-1 gene:YDL079C transcript:YDL079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRK1 description:Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication [Source:SGD;Acc:S000002237]</Hit_def>
  <Hit_accession>YDL079C</Hit_accession>
  <Hit_len>501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>102.064</Hsp_bit-score>
      <Hsp_score>253</Hsp_score>
      <Hsp_evalue>2.02342e-24</Hsp_evalue>
      <Hsp_query-from>156</Hsp_query-from>
      <Hsp_query-to>782</Hsp_query-to>
      <Hsp_hit-from>164</Hsp_hit-from>
      <Hsp_hit-to>378</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>81</Hsp_identity>
      <Hsp_positive>118</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>222</Hsp_align-len>
      <Hsp_qseq>YHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSF-ETDKE----VVVVTDYAEGELFQILEDDGNL----PEEQVREIACQLVSALYYLHS-HRILHRDMKPQNILLGKGGV-VKLCDFGFARAMSINTLVLTSIKGTPLYMSPELV-EEKPYDHTADLWSMGCILYELFVGTPPFYTNS-IFQLVSLI</Hsp_qseq>
      <Hsp_hseq>YPTTEVVGHGSFGVVVTTVIIETNQKVAIKKVLQ----DRRYKN--RELETMKMLCHPNTVGLQYYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYI-CSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEII</Hsp_hseq>
      <Hsp_midline>Y   E++G GSFG V       T Q VA+K + +    D+  +N  RE++ M+ L HPN V +   F E D+E    + +V DY    L+Q L    NL    P  +++  A QL  AL YLH+  RI HRD+KPQN+L+       K+CDFG A+ +  +   ++ I  +  Y +PEL+     Y +  D+WS  C++ EL +G P F   S I QLV +I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>101.679</Hsp_bit-score>
      <Hsp_score>252</Hsp_score>
      <Hsp_evalue>3.37428e-24</Hsp_evalue>
      <Hsp_query-from>168</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>19</Hsp_hit-from>
      <Hsp_hit-to>222</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>207</Hsp_align-len>
      <Hsp_qseq>EMIGEGSFGKVYKGRKRYTGQVV-ALKFI-----PKVGRSDKELRNLRREIDIM-RGLQHPNIVQMLDSFETDKEVVVVTDYAEG-ELFQILEDDGNLPEEQVREIACQLVSALYYLHSH-RILHRDMKPQNILLGKGGVVKLCDFGFA---RAMSINTLVLTSIKGTPLYMSPELV--EEKPYDHTADLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>DTVGQGAFACVKNAHLQMDPSIILAVKFIHVPTCKKMGLSDKDIT---KEVVLQSKCSKHPNVLRLIDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQTPW</Hsp_hseq>
      <Hsp_midline>+ +G+G+F  V     +    ++ A+KFI      K+G SDK++    +E+ +  +  +HPN+++++D   + + + ++ + A+G +LF  +E D  +  +  +    QLVSA+ YLH    + HRD+KP+NILL K G +KL DFG A   R       V    +G+P YM+PE++  EE  Y    D+WS+G +L+ L  G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>99.7525</Hsp_bit-score>
      <Hsp_score>247</Hsp_score>
      <Hsp_evalue>5.05443e-24</Hsp_evalue>
      <Hsp_query-from>156</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>222</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>228</Hsp_align-len>
      <Hsp_qseq>YHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQ----HPNIVQMLDSFETDKEVVVVTDYAE-GELFQILE--------DDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFA-RAMSINTLVLTSIKGTPLYMSPELVE--------EKPYD---------HTADLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>YTKLRSIQSGTFSTVYKAWSTTHNRYVALKITPKYKTSEA---NMKNEYDVMKILSSCNPHPNICSMLDFYTDDSYYIMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQIDMQKIIKQLCSAISFAHSLGIAHRDIKPENILLTINGDIKLADWGHAIQSPKSNDFQI----GTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFGDCLF</Hsp_hseq>
      <Hsp_midline>Y  L  I  G+F  VYK       + VALK  PK   S+    N++ E D+M+ L     HPNI  MLD +  D   ++V +Y E G+L+  L+           +L +  +++I  QL SA+ + HS  I HRD+KP+NILL   G +KL D+G A ++   N   +    GT  Y +PE           +K +D         + AD WS+G  ++ L  G   F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>100.908</Hsp_bit-score>
      <Hsp_score>250</Hsp_score>
      <Hsp_evalue>5.3112e-24</Hsp_evalue>
      <Hsp_query-from>165</Hsp_query-from>
      <Hsp_query-to>872</Hsp_query-to>
      <Hsp_hit-from>194</Hsp_hit-from>
      <Hsp_hit-to>441</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>261</Hsp_align-len>
      <Hsp_qseq>LEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQ-HPNIVQMLDSF---ETDKEVVVVTDYAE-GELFQILE------DDGNLPEEQ-------VREIACQLVSALYYLH-SHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPF-----YTNSIFQLVSLIIKDPV-KWPKNMSSEFRVDRIGADYAKEFPE</Hsp_qseq>
      <Hsp_hseq>LGKIGAGNSGTVVKALHVPDSKIVAKKTIPVEQNNSTIINQLVRELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKL-INSIADTFV-GTSTYMSPERIQGNVYSIKGDVWSLGLMIIELVTGEFPLGGHNDTPDGILDLLQRIVNEPSPRLPK--------DRI---YSKEMTD</Hsp_hseq>
      <Hsp_midline>L  IG G+ G V K       ++VA K IP    +   +  L RE+ I++ ++ H NI+    ++     + E++++ +Y++ G L +IL         G +  ++       + +IA  +++ L +L+  ++I+HRD+KP N+L+   G +KLCDFG ++ + IN++  T + GT  YMSPE ++   Y    D+WS+G ++ EL  G  P        + I  L+  I+ +P  + PK        DRI   Y+KE  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>98.5969</Hsp_bit-score>
      <Hsp_score>244</Hsp_score>
      <Hsp_evalue>4.00784e-23</Hsp_evalue>
      <Hsp_query-from>156</Hsp_query-from>
      <Hsp_query-to>740</Hsp_query-to>
      <Hsp_hit-from>60</Hsp_hit-from>
      <Hsp_hit-to>281</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>222</Hsp_align-len>
      <Hsp_qseq>YHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLD-------------SFETDKEVVVVTDYAEGELFQILEDDG-NLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFAR------------AMSINTLVLTSIKGTPLYMSPELV-EEKPYDHTADLWSMGCILYELFVGTP</Hsp_qseq>
      <Hsp_hseq>YREDEKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKP</Hsp_hseq>
      <Hsp_midline>Y   E +G+G+FG+VYKG    T + VA+K I      D      +REI I++ L H NI+++++             S    K   ++  Y   +L  +L +   NL    ++ +  Q++  L Y+H  + +HRD+K  NIL+   GV+KL DFG AR              + +    TS+  T  Y +PELV  +K Y    D+W +GC+  E F   P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>97.8265</Hsp_bit-score>
      <Hsp_score>242</Hsp_score>
      <Hsp_evalue>5.96338e-23</Hsp_evalue>
      <Hsp_query-from>150</Hsp_query-from>
      <Hsp_query-to>842</Hsp_query-to>
      <Hsp_hit-from>21</Hsp_hit-from>
      <Hsp_hit-to>269</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>120</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>249</Hsp_align-len>
      <Hsp_qseq>EKYHVLEMIGEGSFGKVYKGRKRYTGQ--VVALKFIPKVGRSDKELRNLRREIDIMRGLQ-HPNIVQMLDS---FETDKEV---VVVTDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTL----VLTSIKGTPLYMSPE-LVEEKPYDHTADLWSMGCILYELFVGTPPF----YTNSIFQLVSLIIKDPVKWPKNMSSEFRVDRI</Hsp_qseq>
      <Hsp_hseq>KRFQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYI</Hsp_hseq>
      <Hsp_midline>+++ +++ IG G++G V   R     +   VA+K +  V       +   RE+ ++R  + H NI  + D    F  D  +    +  +  E ++ QI++    L +   +    Q++  L Y+HS  +LHRD+KP N+L+     +K+CDFG AR  S N +     LT    T  Y +PE ++  + Y    D+WS GCIL E   G P F    Y N + Q++ ++   P +  + + S+   D I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>97.8265</Hsp_bit-score>
      <Hsp_score>242</Hsp_score>
      <Hsp_evalue>6.55721e-23</Hsp_evalue>
      <Hsp_query-from>156</Hsp_query-from>
      <Hsp_query-to>758</Hsp_query-to>
      <Hsp_hit-from>177</Hsp_hit-from>
      <Hsp_hit-to>419</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>244</Hsp_align-len>
      <Hsp_qseq>YHVLEMIGEGSFGKVYKGRKRYTGQVVALKFI-PKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQ-ILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIK-----------------------------------------GTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNS</Hsp_qseq>
      <Hsp_hseq>FEMITQVGQGGYGQVYLARKKDTKEVCALKILNKKLLFKLNETKHVLTERDILTTTRSEWLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINTRCLKSGHARFYISEMFCAVNALHDLGYTHRDLKPENFLIDAKGHIKLTDFGLA-AGTISNERIESMKIRLEKIKDLEFPAFTEKSIEDRRKMYNQLREKEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSS</Hsp_hseq>
      <Hsp_midline>+ ++  +G+G +G+VY  RK+ T +V ALK +  K+     E +++  E DI+   +   +V++L +F+  + + +  ++  G  F+ +L +   L     R    ++  A+  LH     HRD+KP+N L+   G +KL DFG A A +I+   + S+K                                         G+P YM+ E++E K YD T D WS+GC+L+E  VG  PF  +S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>98.2117</Hsp_bit-score>
      <Hsp_score>243</Hsp_score>
      <Hsp_evalue>8.61542e-23</Hsp_evalue>
      <Hsp_query-from>165</Hsp_query-from>
      <Hsp_query-to>752</Hsp_query-to>
      <Hsp_hit-from>1099</Hsp_hit-from>
      <Hsp_hit-to>1306</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>210</Hsp_align-len>
      <Hsp_qseq>LEMIGEGSFGKVYKGRKRYTGQVVALKFIPK------VGRSDKELRNLRREIDIMRGLQ---HPNIVQMLDSFETDK----EVVVVTDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYD-HTADLWSMGCILYELFVGTPPFYT</Hsp_qseq>
      <Hsp_hseq>LQKMGEGAYGKVNLCIHKKNRYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKKPHENILRLLDFFEDDDYYYIETPVHGETGCIDLFDLIEFKTNMTEFEAKLIFKQVVAGIKHLHDQGIVHRDIKDENVIVDSKGFVKIIDFG--SAAYVKSGPFDVFVGTIDYAAPEVLGGNPYEGQPQDIWAIGILLYTVVFKENPFYN</Hsp_hseq>
      <Hsp_midline>L+ +GEG++GKV     +    +V +K I K          D++L  +  EI IM  L    H NI+++LD FE D     E  V  +    +LF ++E   N+ E + + I  Q+V+ + +LH   I+HRD+K +N+++   G VK+ DFG   A  + +       GT  Y +PE++   PY+    D+W++G +LY +     PFY </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>96.6709</Hsp_bit-score>
      <Hsp_score>239</Hsp_score>
      <Hsp_evalue>2.43668e-22</Hsp_evalue>
      <Hsp_query-from>153</Hsp_query-from>
      <Hsp_query-to>806</Hsp_query-to>
      <Hsp_hit-from>368</Hsp_hit-from>
      <Hsp_hit-to>589</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>125</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>231</Hsp_align-len>
      <Hsp_qseq>KYHVLEMIGEGSFGKVYKGRKRYTGQVVALK-------FIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQILEDDG--NLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGV--VKLCDFGFA--RAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKDPVKWP</Hsp_qseq>
      <Hsp_hseq>KYLVLDILGQGTFGQVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILELLNQKIDPTN--KH-HFLRMYDSFVHKNHLCLVFELLSNNLYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPELKIIDFGSSCEEARTVYTYIQSR-----FYRAPEIILGIPYSTSIDMWSLGCIVAELFLGIPIFPGASEYNQLTRII-DTLGYP</Hsp_hseq>
      <Hsp_midline>KY VL+++G+G+FG+V K +   T +++A+K       ++ +     K L  L ++ID     +H + ++M DSF     + +V +     L+++L+ +    L  + +R    Q++ +L  L   +++H D+KP+NILL       +K+ DFG +   A ++ T + +       Y +PE++   PY  + D+WS+GCI+ ELF+G P F   S +  ++ II D + +P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>96.2857</Hsp_bit-score>
      <Hsp_score>238</Hsp_score>
      <Hsp_evalue>2.8726e-22</Hsp_evalue>
      <Hsp_query-from>96</Hsp_query-from>
      <Hsp_query-to>836</Hsp_query-to>
      <Hsp_hit-from>347</Hsp_hit-from>
      <Hsp_hit-to>595</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>130</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>261</Hsp_align-len>
      <Hsp_qseq>FKNSSNSQTWEHFWPRTMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQILEDD----GNLPEEQVREIACQLVSALYYL-HSHRILHRDMKPQNILLGKG-GVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELV-----EEKPYDHTADLWSMGCILYELFVGT---PPFYTNSIFQLVSLIIKDPVKWPKNMSSEFRVD</Hsp_qseq>
      <Hsp_hseq>FSNGSSSRI-------TLDELEFLDELGHGNYGNVSKVLHKPTNVIMATKEV-RLELDEAKFRQILMELEVLHKCNSPYIVDFYGAFFIEGAVYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSANQGTVKLCDFGVSGNL-VASLAKTNI-GCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYPPETYDNIFSQLSAIVDGP--PPRLPSDKFSSD</Hsp_hseq>
      <Hsp_midline>F N S+S+        T+++   L+ +G G++G V K   + T  ++A K + ++   + + R +  E++++     P IV    +F  +  V +  +Y +G     + D+    G + E Q+  IA  ++  L  L   H I+HRD+KP NIL     G VKLCDFG +  + + +L  T+I G   YM+PE +     +   Y   +D+WS+G  + E+ +G    PP   ++IF  +S I+  P   P+  S +F  D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YPR111W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:747306:749000:1 gene:YPR111W transcript:YPR111W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF20 description:Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006315]</Hit_def>
  <Hit_accession>YPR111W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.9005</Hsp_bit-score>
      <Hsp_score>237</Hsp_score>
      <Hsp_evalue>3.1769e-22</Hsp_evalue>
      <Hsp_query-from>156</Hsp_query-from>
      <Hsp_query-to>758</Hsp_query-to>
      <Hsp_hit-from>169</Hsp_hit-from>
      <Hsp_hit-to>411</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>243</Hsp_align-len>
      <Hsp_qseq>YHVLEMIGEGSFGKVYKGRKRYTGQVVALKFI-PKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQ-ILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLV----------------------------------------LTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNS</Hsp_qseq>
      <Hsp_hseq>FQILTQVGQGGYGQVYLAKKKDSDEICALKILNKKLLFKLNETNHVLTERDILTTTRSDWLVKLLYAFQDPESLYLAMEFVPGGDFRTLLINTRILKSGHARFYISEMFCAVNALHELGYTHRDLKPENFLIDATGHIKLTDFGLAAGTVSNERIESMKIRLEEVKNLEFPAFTERSIEDRRKIYHNMRKTEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSS</Hsp_hseq>
      <Hsp_midline>+ +L  +G+G +G+VY  +K+ + ++ ALK +  K+     E  ++  E DI+   +   +V++L +F+  + + +  ++  G  F+ +L +   L     R    ++  A+  LH     HRD+KP+N L+   G +KL DFG A     N  +                                          S+ G+P YM+ E++E K YD T D WS+GC+L+E  VG  PF  +S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.1301</Hsp_bit-score>
      <Hsp_score>235</Hsp_score>
      <Hsp_evalue>5.02124e-22</Hsp_evalue>
      <Hsp_query-from>24</Hsp_query-from>
      <Hsp_query-to>821</Hsp_query-to>
      <Hsp_hit-from>85</Hsp_hit-from>
      <Hsp_hit-to>385</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>88</Hsp_identity>
      <Hsp_positive>138</Hsp_positive>
      <Hsp_gaps>59</Hsp_gaps>
      <Hsp_align-len>313</Hsp_align-len>
      <Hsp_qseq>YCDVSSSESKLPSRSCVKYITAAPFKNSSNSQTWEHFWPRTME--KYHVLEMIGEGSFGKVYKGRKRYTGQV--VALKFIPKVG-RSDKELRNLRR-----------EIDIMR--GLQHPNIVQMLDSFETDKEVVVVTDYAEG-ELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILL------GKGG------------------VVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKDPVK----WPKNMSS</Hsp_qseq>
      <Hsp_hseq>FCDIFSTELKLDETS----------NKSTDYSSSNHQYPEQLELHNYKLLNKIGEGAFSRVFKAVGINTDDQAPVAIKAIIKKGISSDAILKGNDRIQGSSRKKVLNEVAIHKLVSKNNPHCTKFIAFQESANYYYLVTELVTGGEIFDRIVQLTCFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLRNNTAKTPC--GTIEYVASEVFTSKRYSMKVDMWSIGCVLFTLLCGYPPFYEKNEKTLLKKISRGDYEFLAPWWDNISS</Hsp_hseq>
      <Hsp_midline>+CD+ S+E KL   S            S++  +  H +P  +E   Y +L  IGEG+F +V+K     T     VA+K I K G  SD  L+   R           E+ I +     +P+  + +   E+     +VT+   G E+F  +       E+  R +  Q+  A+ ++H   I+HRD+KP+N+L       G  G                  +VKL DFG A+ +  NT       GT  Y++ E+   K Y    D+WS+GC+L+ L  G PPFY  +   L+  I +   +    W  N+SS</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>92.8189</Hsp_bit-score>
      <Hsp_score>229</Hsp_score>
      <Hsp_evalue>1.35425e-21</Hsp_evalue>
      <Hsp_query-from>174</Hsp_query-from>
      <Hsp_query-to>812</Hsp_query-to>
      <Hsp_hit-from>47</Hsp_hit-from>
      <Hsp_hit-to>271</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>114</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>233</Hsp_align-len>
      <Hsp_qseq>IGEGSFGKVYKGRKRYTGQVVALKFIPKVG-----RSDKELRNLRREIDIMRGLQHPNIVQMLDSFET-----------DKEVVV--VTDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNIL-LGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPE-LVEEKPYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKDPVKWPKN</Hsp_qseq>
      <Hsp_hseq>IGHGSFGTV-------TQSILSSNSIEWLGPYAIKRVVKSPKVQSLELEILQNIRHPNLVTLEFFFESHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGIAKVCDFGSAQRLDDNTELKTYF-CSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPLFKGDSANSQLEEIAKLLGRFPKS</Hsp_hseq>
      <Hsp_midline>IG GSFG V       T  +++   I  +G     R  K  +    E++I++ ++HPN+V +   FE+            K  V+  +      E+ +  ++   +P + ++    Q++ AL  LHS  I H D+KP NIL +   G+ K+CDFG A+ +  NT + T    +  Y +PE L+  K Y    D+WS+GCI+ E+  G P F  +S    +  I K   ++PK+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.9745</Hsp_bit-score>
      <Hsp_score>232</Hsp_score>
      <Hsp_evalue>1.92724e-21</Hsp_evalue>
      <Hsp_query-from>141</Hsp_query-from>
      <Hsp_query-to>749</Hsp_query-to>
      <Hsp_hit-from>836</Hsp_hit-from>
      <Hsp_hit-to>1050</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>220</Hsp_align-len>
      <Hsp_qseq>RTMEKYHVLEMIGEGSFGKV---YKGRKRYTGQVVALKFIPK------VGRSDKELRNLRREIDIMRGLQ---HPNIVQMLDSFETDK----EVVVVTDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYD-HTADLWSMGCILYELFVGTPPFY</Hsp_qseq>
      <Hsp_hseq>KKFSDFTILQVMGEGAYGKVNLCIHNREHY---IVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKNSQENILKLLDFFEDDDYYYIETPVHGETGSIDLFDVIEFKKDMVEHEAKLVFKQVVASIKHLHDQGIVHRDIKDENVIVDSHGFVKLIDFG--SAAYIKSGPFDVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLYTIIYKENPYY</Hsp_hseq>
      <Hsp_midline>+    + +L+++GEG++GKV      R+ Y   +V +K I K          D++L  +  EI IM  L      NI+++LD FE D     E  V  +    +LF ++E   ++ E + + +  Q+V+++ +LH   I+HRD+K +N+++   G VKL DFG   A  I +       GT  Y +PE++    Y     D+W++G +LY +     P+Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YDL028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:400997:403291:-1 gene:YDL028C transcript:YDL028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MPS1 description:Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]</Hit_def>
  <Hit_accession>YDL028C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.5893</Hsp_bit-score>
      <Hsp_score>231</Hsp_score>
      <Hsp_evalue>2.55628e-21</Hsp_evalue>
      <Hsp_query-from>153</Hsp_query-from>
      <Hsp_query-to>860</Hsp_query-to>
      <Hsp_hit-from>439</Hsp_hit-from>
      <Hsp_hit-to>694</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>130</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>261</Hsp_align-len>
      <Hsp_qseq>KYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQ-HPNIVQMLDSFETDKEVVVVTDYAEGELFQILEDDGNLPEEQ--VREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAM---SINTLVLTSIKGTPLYMSPELVEEKPYDHTA---------------DLWSMGCILYELFVGTPPFYT----NSIFQLVSLIIKDPVKWPKNMSSEFRVDRIGADYAK</Hsp_qseq>
      <Hsp_hseq>QYEKIELLGRGGSSRVYKV-KGSGNRVYALKRVSFDAFDDSSIDGFKGEIELLEKLKDQKRVIQLLDYEMGDGLLYLIMECGDHDLSQILNQRSGMPLDFNFVRFYTKEMLLCIKVVHDAGIVHSDLKPANFVLVKG-ILKIIDFGIANAVPEHTVNIYRETQI-GTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYGKPPYGSFQGQNRLLAIMNPDVKIP--FPEHTSNNEKIPKSAIELMK</Hsp_hseq>
      <Hsp_midline>+Y  +E++G G   +VYK  K    +V ALK +      D  +   + EI+++  L+    ++Q+LD    D  + ++ +  + +L QIL     +P +   VR    +++  +  +H   I+H D+KP N +L KG ++K+ DFG A A+   ++N    T I GTP YM+PE +    Y   +               D+WS GCI+Y++  G PP+ +    N +  +++  +K P  +P++ S+  ++ +   +  K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>91.6633</Hsp_bit-score>
      <Hsp_score>226</Hsp_score>
      <Hsp_evalue>3.26203e-21</Hsp_evalue>
      <Hsp_query-from>168</Hsp_query-from>
      <Hsp_query-to>782</Hsp_query-to>
      <Hsp_hit-from>43</Hsp_hit-from>
      <Hsp_hit-to>253</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>218</Hsp_align-len>
      <Hsp_qseq>EMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSF-ETDKE----VVVVTDYAEGELFQ----ILEDDGNLPEEQVREIACQLVSALYYLHSH-RILHRDMKPQNILLG-KGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELV-EEKPYDHTADLWSMGCILYELFVGTPPFYTNS-IFQLVSLI</Hsp_qseq>
      <Hsp_hseq>EVVGHGSFGVVFATVIQETNEKVAIKKV----LQDKRFKN--RELEIMKMLSHINIIDLKYFFYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVSYI-CSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEII</Hsp_hseq>
      <Hsp_midline>E++G GSFG V+    + T + VA+K +      DK  +N  RE++IM+ L H NI+ +   F E D +    + ++ +Y    L+Q     +     +   +++    QL  +L YLH    + HRD+KPQN+L+  +   +KLCDFG A+ +      ++ I  +  Y +PEL+     Y +  D+WS GC++ EL +G P F   S I QLV +I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.2041</Hsp_bit-score>
      <Hsp_score>230</Hsp_score>
      <Hsp_evalue>3.32381e-21</Hsp_evalue>
      <Hsp_query-from>150</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>350</Hsp_hit-from>
      <Hsp_hit-to>611</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>118</Hsp_positive>
      <Hsp_gaps>63</Hsp_gaps>
      <Hsp_align-len>262</Hsp_align-len>
      <Hsp_qseq>EKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDK-ELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDY-AEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFA------------------------------------------RAMSINTLVLT-------------------SIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>EDFHTVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSNYYKKLLQQDEATNGISKPGTYNANTTDTANKRQTMVVDSISLTMSNRQQIQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPF</Hsp_hseq>
      <Hsp_midline>E +H +++IG+G+FG+V   +K+ TG++ A+K + K     K +L +++ E D++ G   P +V +  SF+  + + ++ ++   G+L  +L       E+  R    + + A+  +H    +HRD+KP NIL+   G +KL DFG +                                          + M ++++ LT                   S  GTP Y++PE+   + Y    D WS+G I+YE  +G PPF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>91.6633</Hsp_bit-score>
      <Hsp_score>226</Hsp_score>
      <Hsp_evalue>6.20844e-21</Hsp_evalue>
      <Hsp_query-from>171</Hsp_query-from>
      <Hsp_query-to>749</Hsp_query-to>
      <Hsp_hit-from>167</Hsp_hit-from>
      <Hsp_hit-to>386</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>227</Hsp_align-len>
      <Hsp_qseq>MIGEGSFGKV---YKGRKR-----YTGQVVALKFIP-KVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSF-ETDKEVVVVTDYAEG-ELFQILEDDG---NLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGK---GGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPEL-----------------VEEKPYDHTADLWSMGCILYELFVGTPPFY</Hsp_qseq>
      <Hsp_hseq>IVGNGTFGHVLITHNSKERDEDVCYHPENYAVKIIKLKPNKFDKEARILLR-------LDHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGISPFY</Hsp_hseq>
      <Hsp_midline>++G G+FG V   +  ++R     Y  +  A+K I  K  + DKE R L R       L HPNI+++  +F + +  + +  D   G +LF  L       ++ E +   I  Q++ AL YLH   I+HRD+K  NILL        + L DFG A+ ++ N   + ++ GTP Y +PE+                 +E++ YD   DLWS+G I + +  G  PFY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>71</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.8929</Hsp_bit-score>
      <Hsp_score>224</Hsp_score>
      <Hsp_evalue>1.51655e-20</Hsp_evalue>
      <Hsp_query-from>294</Hsp_query-from>
      <Hsp_query-to>749</Hsp_query-to>
      <Hsp_hit-from>206</Hsp_hit-from>
      <Hsp_hit-to>365</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>163</Hsp_align-len>
      <Hsp_qseq>REIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQILE-----DDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKG-----TPLYMSPE-LVEEKPYDHTADLWSMGCILYELFVGTPPFY</Hsp_qseq>
      <Hsp_hseq>REMALCRELHNKHLTTLVEIFLERKCVHMVYEYAEHDLLQIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDGCVKIGDLGLAR--KFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAEL-IGLQPIF</Hsp_hseq>
      <Hsp_midline>RE+ + R L + ++  +++ F   K V +V +YAE +L QI+      +   +P   VR I  QL+  + YLH + +LHRD+KP NI++   G VK+ D G AR    + ++ T   G     T  Y +PE L+  + Y    DLWS+GCI  EL +G  P +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>72</Hit_num>
  <Hit_id>YFL033C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:69115:74427:-1 gene:YFL033C transcript:YFL033C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM15 description:Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase [Source:SGD;Acc:S000001861]</Hit_def>
  <Hit_accession>YFL033C</Hit_accession>
  <Hit_len>1770</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.5817</Hsp_bit-score>
      <Hsp_score>218</Hsp_score>
      <Hsp_evalue>1.56581e-19</Hsp_evalue>
      <Hsp_query-from>144</Hsp_query-from>
      <Hsp_query-to>593</Hsp_query-to>
      <Hsp_hit-from>790</Hsp_hit-from>
      <Hsp_hit-to>942</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>153</Hsp_align-len>
      <Hsp_qseq>TMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGR-SDKELRNLRREIDIMR-GLQHPNIVQMLDSFETDKEVVVVTDYAEG-ELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARA</Hsp_qseq>
      <Hsp_hseq>SIKDYDILKPISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDKPYVARLFASFQNKDNLFLVMEYLPGGDLATLIKMMGYLPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLIDNAGHVKLTDFGLSRA</Hsp_hseq>
      <Hsp_midline>+++ Y +L+ I +G++G VY  RK+ TG   A+K + K    +  ++ N++ E  IM      P + ++  SF+    + +V +Y  G +L  +++  G LP++  ++   ++V  +  +H + I+H D+KP+N+L+   G VKL DFG +RA</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>3.98234e-09</Hsp_evalue>
      <Hsp_query-from>630</Hsp_query-from>
      <Hsp_query-to>809</Hsp_query-to>
      <Hsp_hit-from>1149</Hsp_hit-from>
      <Hsp_hit-to>1209</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>38</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>61</Hsp_align-len>
      <Hsp_qseq>GTPLYMSPELVEEKPYDHT-ADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKDPVKWPK</Hsp_qseq>
      <Hsp_hseq>GTPDYLAPETIEGKGEDNKQCDWWSVGCIFFELLLGYPPFHAETPDAVFKKILSGVIQWPE</Hsp_hseq>
      <Hsp_midline>GTP Y++PE +E K  D+   D WS+GCI +EL +G PPF+  +   +   I+   ++WP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>73</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.0409</Hsp_bit-score>
      <Hsp_score>214</Hsp_score>
      <Hsp_evalue>1.71647e-19</Hsp_evalue>
      <Hsp_query-from>156</Hsp_query-from>
      <Hsp_query-to>773</Hsp_query-to>
      <Hsp_hit-from>23</Hsp_hit-from>
      <Hsp_hit-to>249</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>227</Hsp_align-len>
      <Hsp_qseq>YHVLEMIGEGSFGKVYKGRKRYTGQV--VALKFIPKVGRSDKELRNLRREIDIMRGLQ-HPNIVQMLDS---FETD---KEVVVVTDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTS-IKG---TPLYMSPE-LVEEKPYDHTADLWSMGCILYELFVGTPPF-------YTNSIFQLV</Hsp_qseq>
      <Hsp_hseq>FHLTGKIGRGSHSLICSSTYTESNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLYEELMECDLSQIIRSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFEGKDYVDHLNHILQIL</Hsp_hseq>
      <Hsp_midline>+H+   IG GS   +       + +   VA++ IP    +    +   RE+ ++R L+ HPNIV + D+   F  +     V +  +  E +L QI+  +  L +   +    Q++ AL Y+HS  +LH D+KP+N+L+     +K+C+FG + + S N  V    IKG   +  Y +PE L+  +      D+WS GCIL EL    P F       + N I Q++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>74</Hit_num>
  <Hit_id>YDL214C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:74446:76545:-1 gene:YDL214C transcript:YDL214C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR2 description:Serine/threonine protein kinase; inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance; PRR2 has a paralog, NPR1, that arose from the whole genome duplication [Source:SGD;Acc:S000002373]</Hit_def>
  <Hit_accession>YDL214C</Hit_accession>
  <Hit_len>699</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.4261</Hsp_bit-score>
      <Hsp_score>215</Hsp_score>
      <Hsp_evalue>2.31332e-19</Hsp_evalue>
      <Hsp_query-from>153</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>359</Hsp_hit-from>
      <Hsp_hit-to>564</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>210</Hsp_align-len>
      <Hsp_qseq>KYHVLEMI-GEGSFGKVYKGRKRYTGQVVALK-FIPKVGRSD--KELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQILEDDGNLPEEQVREIAC---QLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFG----FARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTA-DLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>KYRDLDVVLGEGSGGKVKLVQRVLDNKVFALKEYRSKKKRESERKYIKNIISEYCIASTLKNPNICETLEILYEKGKIFQILEYCEYDLFSLVMSE----KMHYEEICCLFKQLINGVKYLHDIGLSHRDLKLDNCVVTRRGILKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFYFNEYDPRALDVWSVGIIFFCMITRRFPW</Hsp_hseq>
      <Hsp_midline>KY  L+++ GEGS GKV   ++    +V ALK +  K  R    K ++N+  E  I   L++PNI + L+      ++  + +Y E +LF ++  +    +    EI C   QL++ + YLH   + HRD+K  N ++ + G++KL DFG    F   +S   +    I G+  Y+SPE+     YD  A D+WS+G I + +     P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>75</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.2705</Hsp_bit-score>
      <Hsp_score>212</Hsp_score>
      <Hsp_evalue>6.17484e-19</Hsp_evalue>
      <Hsp_query-from>150</Hsp_query-from>
      <Hsp_query-to>755</Hsp_query-to>
      <Hsp_hit-from>313</Hsp_hit-from>
      <Hsp_hit-to>541</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>229</Hsp_align-len>
      <Hsp_qseq>EKY-HVLEMIGEGSFGKVYKGRKRYTG--------QVVALK-FIPKVGRS-DKELRNLRREIDIMRGLQHPNIVQMLDSFETDK-EVVVVTDY-AEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFG----FARAMSINTLVLTSIKGTPLYMSPELVEEKPYD-HTADLWSMGCILYELFVGTP---------PFYTN</Hsp_qseq>
      <Hsp_hseq>EKYGRCQEVLGKGAFGVVRICQKKNVSSQDGNKSEKLYAVKEFKRRTSESAEKYSKRLTSEFCISSSLHHTNIVTTLDLFQDAKGEYCEVMEYCAGGDLFTLVVAAGKLEYMEADCFFKQLIRGVVYMHEMGVCHRDLKPENLLLTHDGVLKITDFGNSECFKMAWEKNIHLSGGVCGSSPYIAPEEYIKEEFDPRPVDIWACGVIYMAMRTGRQLWSSAEKDDPFYMN</Hsp_hseq>
      <Hsp_midline>EKY    E++G+G+FG V   +K+           ++ A+K F  +   S +K  + L  E  I   L H NIV  LD F+  K E   V +Y A G+LF ++   G L   +      QL+  + Y+H   + HRD+KP+N+LL   GV+K+ DFG    F  A   N  +   + G+  Y++PE   ++ +D    D+W+ G I   +  G           PFY N</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>76</Hit_num>
  <Hit_id>YDL025C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:405344:407206:-1 gene:YDL025C transcript:YDL025C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RTK1 description:Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002183]</Hit_def>
  <Hit_accession>YDL025C</Hit_accession>
  <Hit_len>620</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>84.3445</Hsp_bit-score>
      <Hsp_score>207</Hsp_score>
      <Hsp_evalue>2.68506e-18</Hsp_evalue>
      <Hsp_query-from>147</Hsp_query-from>
      <Hsp_query-to>719</Hsp_query-to>
      <Hsp_hit-from>298</Hsp_hit-from>
      <Hsp_hit-to>501</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>206</Hsp_align-len>
      <Hsp_qseq>MEKYHVL-EMIGEGSFGKVYKGRKRYTGQVVALKFIPKV-----GRSDKELRNLRREID----IMRGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSI---NTLVLT-SIKGTPLYMSPELVEEKPYD-HTADLWSMGCILY</Hsp_qseq>
      <Hsp_hseq>LEKYGIPGRKLGEGASGSV-SVVERTDGKLFACKMFRKPHLNNEGTNQSQLANYSKKVTTEFCIGSTLHHENIVETLDMLTEGDTYLLVMEYAPYDFFNLVMSNL-MTQDEVNCYFKQLCHGVNYLHSMGLAHRDLKLDNCVVTKDGILKLIDFGSAVVFQYPYEDTIVKSHGIVGSDPYLAPELLKQTSYDPRVADVWSIAIIFY</Hsp_hseq>
      <Hsp_midline>+EKY +    +GEG+ G V    +R  G++ A K   K      G +  +L N  +++     I   L H NIV+ LD        ++V +YA  + F ++  +  + +++V     QL   + YLHS  + HRD+K  N ++ K G++KL DFG A        +T+V +  I G+  Y++PEL+++  YD   AD+WS+  I Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>77</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.8037</Hsp_bit-score>
      <Hsp_score>203</Hsp_score>
      <Hsp_evalue>4.11589e-18</Hsp_evalue>
      <Hsp_query-from>174</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>41</Hsp_hit-from>
      <Hsp_hit-to>240</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>208</Hsp_align-len>
      <Hsp_qseq>IGEGSFGKVYKG-----RKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFE----TDKEVV------VVTDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLG-KGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEE-KPYDHTADLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>IGRGAFGTVVQAYLTQDKKNWLGPF-AIKKVP----AHTEYKS--RELQILRIADHPNIVKLQYFFTHLSPQDNKVYQHLAMECLPETLQIEINRYVTNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSISYI-CSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIF</Hsp_hseq>
      <Hsp_midline>IG G+FG V +      +K + G   A+K +P    +  E ++  RE+ I+R   HPNIV++   F      D +V        + +  + E+ + + +   +P + +R    Q+   + YLH   + HRD+KP N+L+  + GV+K+CDFG A+ +  N   ++ I  +  Y +PEL+     Y    D+W +GC++ E+ +G   F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>78</Hit_num>
  <Hit_id>YOR061W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:441534:442553:1 gene:YOR061W transcript:YOR061W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA2 description:Alpha&apos; catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000005587]</Hit_def>
  <Hit_accession>YOR061W</Hit_accession>
  <Hit_len>339</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.6481</Hsp_bit-score>
      <Hsp_score>200</Hsp_score>
      <Hsp_evalue>5.99929e-18</Hsp_evalue>
      <Hsp_query-from>48</Hsp_query-from>
      <Hsp_query-to>758</Hsp_query-to>
      <Hsp_hit-from>6</Hsp_hit-from>
      <Hsp_hit-to>247</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>121</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>255</Hsp_align-len>
      <Hsp_qseq>SKLPSRSCVKYITAAPFKNSSNSQTWEHF---------WPRTMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQH-PNIVQMLDSFE-TDKEV-VVVTDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGG-VVKLCDFGFAR----AMSINTLVLTSIKGTPLYMSPE-LVEEKPYDHTADLWSMGCILYELFVGTPPFYTNS</Hsp_qseq>
      <Hsp_hseq>STLNQKSNRVYSVARVYKNACEERPQEYWDYEQGVTIDWGK-ISNYEIINKIGRGKYSEVFSGRCIVNNQKCVIKVLKPV-----KMKKIYRELKILTNLTGGPNVVGLYDIVQDADSKIPALIFEEIKNVDFRTLYPTFKLPD--IQYYFTQLLIALDYCHSMGIMHRDVKPQNVMIDPTERKLRLIDWGLAEFYHPGVDYNVRV-----ASRYHKGPELLVNLNQYDYSLDLWSVGCMLAAIVFKKEPFFKGS</Hsp_hseq>
      <Hsp_midline>S L  +S   Y  A  +KN+   +  E++         W + +  Y ++  IG G + +V+ GR     Q   +K +  V     +++ + RE+ I+  L   PN+V + D  +  D ++  ++ +  +   F+ L     LP+  ++    QL+ AL Y HS  I+HRD+KPQN+++      ++L D+G A      +  N  V      +  +  PE LV    YD++ DLWS+GC+L  +     PF+  S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>79</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.6481</Hsp_bit-score>
      <Hsp_score>200</Hsp_score>
      <Hsp_evalue>1.52047e-17</Hsp_evalue>
      <Hsp_query-from>285</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>255</Hsp_hit-from>
      <Hsp_hit-to>445</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>192</Hsp_align-len>
      <Hsp_qseq>NLRREIDIMRGLQHPNIVQMLDS----FETDK----EVVVVTDYA------------EGELFQ-ILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLG----------------KGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYD-HTADLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>SLTRELQVLKSLNHPCIVKLLGINNPIFVTSKKPLCDLIIKTPRALPPCDMIMSYCPAGDLLAAVMARNGRLEAWLIQRIFTEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLCKKIENNEMC-TARCGSEDYVSPEILMGVPYDGHLSDTWALGVILYSLFEDRLPF</Hsp_hseq>
      <Hsp_midline>+L RE+ +++ L HP IV++L      F T K    ++++ T  A             G+L   ++  +G L    ++ I  ++V A+ YLH + I+HRD+K +NILL                 K   ++L DFG  + +  N +  T+  G+  Y+SPE++   PYD H +D W++G ILY LF    PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>80</Hit_num>
  <Hit_id>YMR291W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:852630:854390:1 gene:YMR291W transcript:YMR291W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TDA1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000004905]</Hit_def>
  <Hit_accession>YMR291W</Hit_accession>
  <Hit_len>586</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.4925</Hsp_bit-score>
      <Hsp_score>197</Hsp_score>
      <Hsp_evalue>3.77572e-17</Hsp_evalue>
      <Hsp_query-from>174</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>45</Hsp_hit-from>
      <Hsp_hit-to>292</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>63</Hsp_gaps>
      <Hsp_align-len>251</Hsp_align-len>
      <Hsp_qseq>IGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQ-------------------HPNIVQMLDSFETDKEVVVVTDYAE-GELFQ-ILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILL-------------GKGGVVK---------LCDFGFARAMSINTLVLTSIK---GTPLYMSPELVEEK--------------PYDHTADLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>LGDGNFSVVKECMNIHTKDLYAMKLIKKQTVKNK-IQLIQREFDLLRSISEKIRDMEKKNEHSLDIFEGHHHILQLFDYFETADNIVLITQLCQKGDLYEKIVENQCLDLETQVTSYCACLVSVLEFLHSQGIVHRDLKAENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLVLADFGL--AAEYNTSKVNSLKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGCPVDIWALGVLTYFMAFGYTPF</Hsp_hseq>
      <Hsp_midline>+G+G+F  V +    +T  + A+K I K    +K ++ ++RE D++R +                    H +I+Q+ D FET   +V++T   + G+L++ I+E+     E QV      LVS L +LHS  I+HRD+K +N+L                 G  K         L DFG   A   NT  + S+K   GT  Y++PE+V+ K               Y    D+W++G + Y +  G  PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>81</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.1073</Hsp_bit-score>
      <Hsp_score>196</Hsp_score>
      <Hsp_evalue>6.07206e-17</Hsp_evalue>
      <Hsp_query-from>156</Hsp_query-from>
      <Hsp_query-to>782</Hsp_query-to>
      <Hsp_hit-from>163</Hsp_hit-from>
      <Hsp_hit-to>432</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>75</Hsp_gaps>
      <Hsp_align-len>277</Hsp_align-len>
      <Hsp_qseq>YHVLEMIGEGSFGKVYKG-----------RKRYTGQVVALKFIPKVGRS---------------------DKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDY-AEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILL----------------------GKGGVV------------KLCDFGFARAM-SINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLI</Hsp_qseq>
      <Hsp_hseq>YKLINKIGEGAFSKVFRAIPAKNSSNEFLTKNY--KAVAIKVIKKADLSSINGDHRKKDKGKDSTKTSSRDQVLKEVALHKTVSAGCSQ--IVAFIDFQETDSYYYIIQELLTGGEIFGEIVRLTYFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKNTKTPC---GTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTMLCGFPPFYDEKIDTLTEKI</Hsp_hseq>
      <Hsp_midline>Y ++  IGEG+F KV++             K Y  + VA+K I K   S                     D+ L+ +     +  G     IV  +D  ETD    ++ +    GE+F  +       E+  R +  QL  A+ ++HS  ++HRD+KP+N+L                          G+             KL DFG ++ + S NT       GT  Y +PE+V+++ Y    D+W +GC+LY +  G PPFY   I  L   I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>82</Hit_num>
  <Hit_id>YNL183C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:293137:295509:-1 gene:YNL183C transcript:YNL183C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NPR1 description:Protein kinase; stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p; negatively regulates Ldb19p-mediated endocytosis through phosphorylation of Ldb19p, which prevents its association with the plasma membrane; Npr1p activity is negatively regulated via phosphorylation by the TOR complex; NPR1 has a paralog, PRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005127]</Hit_def>
  <Hit_accession>YNL183C</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.1073</Hsp_bit-score>
      <Hsp_score>196</Hsp_score>
      <Hsp_evalue>6.973e-17</Hsp_evalue>
      <Hsp_query-from>279</Hsp_query-from>
      <Hsp_query-to>911</Hsp_query-to>
      <Hsp_hit-from>482</Hsp_hit-from>
      <Hsp_hit-to>712</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>235</Hsp_align-len>
      <Hsp_qseq>LRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQILEDDGNLPEEQVREIAC---QLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFG----FARAMSINTLVLTSIKGTPLYMSPELVEEKPYD-HTADLWS----MGCILYELFVGTPPFYTNSIFQLV----------SLIIK--DPVKWPKNMSSEFRVDRIGADYAKEFPEVEVGSRTLTRQDP</Hsp_qseq>
      <Hsp_hseq>VKKITSEYCIGTTLNHPNIIETIEIVYENDRILQVMEYCEYDLFAIVMSN----KMSYEEICCCFKQILTGVQYLHSIGLAHRDLKLDNCVINEKGIVKLIDFGAAVVFSYPFSKNLVEASGIVGSDPYLAPEVCIFAKYDPRPVDIWSSAIIFACMILKKFPWKIPKLRDNSFKLFCSGRDCDSLSSLVTRTPDPPSYDESHSTEKKKPESSSNNVSDPNNVNIGPQRLLHSLP</Hsp_hseq>
      <Hsp_midline>++ +  E  I   L HPNI++ ++    +  ++ V +Y E +LF I+  +    +    EI C   Q+++ + YLHS  + HRD+K  N ++ + G+VKL DFG    F+   S N +  + I G+  Y++PE+     YD    D+WS      C++ + F    P   ++ F+L           SL+ +  DP  + ++ S+E +     ++   +   V +G + L    P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>83</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.1814</Hsp_bit-score>
      <Hsp_score>191</Hsp_score>
      <Hsp_evalue>3.2626e-16</Hsp_evalue>
      <Hsp_query-from>297</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>134</Hsp_hit-from>
      <Hsp_hit-to>289</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>164</Hsp_align-len>
      <Hsp_qseq>EIDIMRGL-QHPNIVQMLDSFETDKEVVVVTDY-AEGELFQILEDDGNLPEE--QVREIACQLVSALYYLHSHRILHRDMKPQNILL-GKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVE--------EKPYD-HTADLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>EVDIQTKIGRHQNIAALLDFFDS----YIIMEYCSGGDLYEAIKADA-VPKKTKSITHIITQIMDAIEYVHNKGIYHRDIKPENILISGIDWTIKLTDWGLA---TTDKTSMDRNVGSERYMSPELFDSNLDIKERKEPYDCAKVDLWAMGIVFLNIVFHKNPF</Hsp_hseq>
      <Hsp_midline>E+DI   + +H NI  +LD F++     ++ +Y + G+L++ ++ D  +P++   +  I  Q++ A+ Y+H+  I HRD+KP+NIL+ G    +KL D+G A   + +   +    G+  YMSPEL +        ++PYD    DLW+MG +   +     PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>84</Hit_num>
  <Hit_id>YIL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:287790:288908:-1 gene:YIL035C transcript:YIL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA1 description:Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000001297]</Hit_def>
  <Hit_accession>YIL035C</Hit_accession>
  <Hit_len>372</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.0998</Hsp_bit-score>
      <Hsp_score>183</Hsp_score>
      <Hsp_evalue>1.29638e-15</Hsp_evalue>
      <Hsp_query-from>324</Hsp_query-from>
      <Hsp_query-to>782</Hsp_query-to>
      <Hsp_hit-from>130</Hsp_hit-from>
      <Hsp_hit-to>285</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>159</Hsp_align-len>
      <Hsp_qseq>HPNIVQMLDSFE--TDKEVVVVTDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLG-KGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPE-LVEEKPYDHTADLWSMGCILYELFVGTPPFY--TNSIFQLVSLI</Hsp_qseq>
      <Hsp_hseq>HANIIHLFDIIKDPISKTPALVFEYVDNVDFRILY--PKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRV-ASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIV</Hsp_hseq>
      <Hsp_midline>H NI+ + D  +    K   +V +Y +   F+IL     L + ++R    +L+ AL Y HS  I+HRD+KP N+++  K   ++L D+G A    +N      +  +  +  PE LV+ + YD++ DLWS G +L  +     PF+  T++  QLV ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>85</Hit_num>
  <Hit_id>YOR267C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:822588:824867:-1 gene:YOR267C transcript:YOR267C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRK1 description:Protein kinase; implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005793]</Hit_def>
  <Hit_accession>YOR267C</Hit_accession>
  <Hit_len>759</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.7146</Hsp_bit-score>
      <Hsp_score>182</Hsp_score>
      <Hsp_evalue>4.52025e-15</Hsp_evalue>
      <Hsp_query-from>150</Hsp_query-from>
      <Hsp_query-to>779</Hsp_query-to>
      <Hsp_hit-from>212</Hsp_hit-from>
      <Hsp_hit-to>436</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>226</Hsp_align-len>
      <Hsp_qseq>EKYHVL-EMIGEGSFGKVYKGRKRYTGQVVALK-FIP-KVGRSDKE-LRNLRREIDIMRGLQHPNIVQMLDSFETDKE--VVVVTDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFG----FARAMSINTLVLTSIKGTPLYMSPELV-EEKPYD-HTADLWSMG----CILYELFVGTPPFYTNSIFQLVSL</Hsp_qseq>
      <Hsp_hseq>QKYGKLGKLLGSGAGGSVKVLVRPTDGATFAVKEFRPRKPNESVKEYAKKCTAEFCIGSTLHHPNVIETVDVFSDSKQNKYYEVMEYCPIDFFAVVMT-GKMSRGEINCCLKQLTEGVKYLHSMGLAHRDLKLDNCVMTSQGILKLIDFGSAVVFRYPFEDGVTMAHGIVGSDPYLAPEVITSTKSYDPQCVDIWSIGIIYCCMVLKRFPWKAPRDSDDNFRLYCM</Hsp_hseq>
      <Hsp_midline>+KY  L +++G G+ G V    +   G   A+K F P K   S KE  +    E  I   L HPN+++ +D F   K+     V +Y   + F ++   G +   ++     QL   + YLHS  + HRD+K  N ++   G++KL DFG    F         +   I G+  Y++PE++   K YD    D+WS+G    C++ + F    P  ++  F+L  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>86</Hit_num>
  <Hit_id>YIL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:183937:186369:1 gene:YIL095W transcript:YIL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRK1 description:Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton and reduces endocytic ability of cell through the phosphorylation of the Pan1p-Sla1p-End3p protein complex; PRK1 has a paralog, ARK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001357]</Hit_def>
  <Hit_accession>YIL095W</Hit_accession>
  <Hit_len>810</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>2.66051e-14</Hsp_evalue>
      <Hsp_query-from>162</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>24</Hsp_hit-from>
      <Hsp_hit-to>245</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>VLEMIGEGSFGKVYKGR----KRYTGQVVA-LKFIPKVGRSDKELRNLRREIDIMRGLQH-PNIVQMLDSFETDK------EVVVVTDYAE-GELFQILED--DGNLPEEQVREIACQLVSALYYLHSHR--ILHRDMKPQNILLGKGGVVKLCDFGFARAM---SINTLVLTSIK------GTPLYMSPELVE---EKPYDHTADLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>IIKYLTSGGFAQVYTAEISPPDPYSNANIACLKRV--IVPHKQGLNTLRAEVDAMKLLRNNKHVVSYIDSHAARSVNGIAYEVFVLMEFCERGGLIDFMNTRLQNRLQESEILEIMSQTVQGITAMHALQPPLIHRDIKIENVLISHDGLYKVCDFGSVSGVIRPPRNTQEFNYVQHDILTNTTAQYRSPEMIDLYRGLPIDEKSDIWALGVFLYKICYYTTPF</Hsp_hseq>
      <Hsp_midline>+++ +  G F +VY         Y+   +A LK +  +    + L  LR E+D M+ L++  ++V  +DS           EV V+ ++ E G L   +       L E ++ EI  Q V  +  +H+ +  ++HRD+K +N+L+   G+ K+CDFG    +     NT     ++       T  Y SPE+++     P D  +D+W++G  LY++   T PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>87</Hit_num>
  <Hit_id>YPL026C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:500675:502183:-1 gene:YPL026C transcript:YPL026C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKS1 description:Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway; SKS1 has a paralog, VHS1, that arose from the whole genome duplication [Source:SGD;Acc:S000005947]</Hit_def>
  <Hit_accession>YPL026C</Hit_accession>
  <Hit_len>502</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>2.72119e-14</Hsp_evalue>
      <Hsp_query-from>246</Hsp_query-from>
      <Hsp_query-to>725</Hsp_query-to>
      <Hsp_hit-from>84</Hsp_hit-from>
      <Hsp_hit-to>268</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>191</Hsp_align-len>
      <Hsp_qseq>FIPKVGR------SDKELRNL--RREIDI-MRGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQILEDDGNLPEE--QVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGF---ARAMSINTLVLTSIKGTPLYMSPELV-----------------EEKPYDHTADLWSMGCILYEL</Hsp_qseq>
      <Hsp_hseq>FLPSVDLDSILQLTENELNRLPHYREIAFQLRVQSHGNIVKIHQVLESSIATFIVMDYYDRDLFTSIVDDKHFVNHGILIKKVFLQLCSALDHCHRLGIYHCDIKPENVLLDRNDNAYLCDFGLSTKSKYLAPNVCV-----GSSYYMAPERILYCLNTTTNGIHVDECCSSLPTD-TGDIWSLGIILINL</Hsp_hseq>
      <Hsp_midline>F+P V        ++ EL  L   REI   +R   H NIV++    E+     +V DY + +LF  + DD +       ++++  QL SAL + H   I H D+KP+N+LL +     LCDFG    ++ ++ N  V     G+  YM+PE +                    P D T D+WS+G IL  L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>88</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>4.57979e-14</Hsp_evalue>
      <Hsp_query-from>330</Hsp_query-from>
      <Hsp_query-to>896</Hsp_query-to>
      <Hsp_hit-from>770</Hsp_hit-from>
      <Hsp_hit-to>975</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>212</Hsp_align-len>
      <Hsp_qseq>NIVQMLDSFETDKEVVVVTDYAEGE-LFQILEDDG-NLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFA----RAMSINTL----------VLTSIKGTPLYMSPELVE-EKPYDHTADLWSMGCILYELFVGTPPFYT-----NSIFQLVSLIIKDPVKWPKN-MSSEFRVDRIGADYAKEFPEVEVGSRTL</Hsp_qseq>
      <Hsp_hseq>NFVKPMTAVKKKSTLFIQMEYCENRTLYDLIHSENLNQQRDEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNVKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVLDGTGHYNEKIDMYSLGIIFFEMIY---PFSTGMERVNILKKLRSVSIEFPPDFDDNKMKVEKKIIRLLIDHD---PNKRPGARTL</Hsp_hseq>
      <Hsp_midline>N V+ + + +    + +  +Y E   L+ ++  +  N   ++   +  Q++ AL Y+HS  I+HRD+KP NI + +   VK+ DFG A    R++ I  L           LTS  GT +Y++ E+++    Y+   D++S+G I +E+     PF T     N + +L S+ I+ P  +  N M  E ++ R+  D+    P    G+RTL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>89</Hit_num>
  <Hit_id>YNL154C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:343636:345276:-1 gene:YNL154C transcript:YNL154C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YCK2 description:Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform; shares redundant functions with Yck1p in morphogenesis, proper septin assembly, endocytic trafficking, and glucose sensing; stabilized by Sod1p binding in the presence of glucose and oxygen, causing glucose repression of respiratory metabolism; involved in the phosphorylation and regulation of glucose sensor Rgt2p; YCK2 has a paralog, YCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005098]</Hit_def>
  <Hit_accession>YNL154C</Hit_accession>
  <Hit_len>546</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>4.61149e-14</Hsp_evalue>
      <Hsp_query-from>156</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>76</Hsp_hit-from>
      <Hsp_hit-to>282</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>210</Hsp_align-len>
      <Hsp_qseq>YHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQILEDDGN-LPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGV-----VKLCDFGFAR-------AMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>YKIGKKIGEGSFGVLFEGTNMINGLPVAIKFEPRKTEA-PQLKDEYRTYKILAGT--PGIPQEYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANKVHLIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEAMGHVFFYFLRGQLPW</Hsp_hseq>
      <Hsp_midline>Y + + IGEGSFG +++G     G  VA+KF P+   +  +L++  R   I+ G   P I Q     +     ++V D     L  + +  G     + V ++A Q+++ +  LH+H +++RD+KP N L+G+ G      V L DFG A+          I      S+ GT  YMS      +      D+ +MG + +    G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>90</Hit_num>
  <Hit_id>YKL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:347214:349136:-1 gene:YKL048C transcript:YKL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ELM1 description:Serine/threonine protein kinase; regulates the orientation checkpoint, the morphogenesis checkpoint and the metabolic switch from fermentative to oxidative metabolism by phosphorylating the activation loop of Kin4p, Hsl1p and Snf4p respectively; cooperates with Hsl7p in recruiting Hsl1p to the septin ring, a prerequisite for subsequent recruitment, phosphorylation, and degradation of Swe1p; forms part of the bud neck ring; regulates cytokinesis [Source:SGD;Acc:S000001531]</Hit_def>
  <Hit_accession>YKL048C</Hit_accession>
  <Hit_len>640</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.8626</Hsp_bit-score>
      <Hsp_score>172</Hsp_score>
      <Hsp_evalue>6.32487e-14</Hsp_evalue>
      <Hsp_query-from>141</Hsp_query-from>
      <Hsp_query-to>788</Hsp_query-to>
      <Hsp_hit-from>83</Hsp_hit-from>
      <Hsp_hit-to>368</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>120</Hsp_positive>
      <Hsp_gaps>70</Hsp_gaps>
      <Hsp_align-len>286</Hsp_align-len>
      <Hsp_qseq>RTMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPK------------------------------VGRSDKELRNL---RREIDIMRGLQHP-NIVQMLDSFET--DKEVVVVTDYAE-GELFQILEDDGN-LPEEQ------------VREIACQLVSALYYLHSHRILHRDMKPQNILLG-KGGVVKLCDFG----------FARAMSINTLV--LTSIKGTPLYMSPELVE--EKPYDHTA-----DLWSMGCILYELFVGTPPFYTNSIFQLVSLIIK</Hsp_qseq>
      <Hsp_hseq>KTINQYTLGVSAGSGQFGYVRKAYSSTLGKVVAVKIIPKKPWNAQQYSVNQVMRQIQLWKSKGKITTNMSGNEAMRLMNIEKCRWEIFAASRLRNNVHIVRLIECLDSPFSESIWIVTNWCSLGELQWKRDDDEDILPQWKKIVISNCSVSTFAKKILEDMTKGLEYLHSQGCIHRDIKPSNILLDEEEKVAKLSDFGSCIFTPQSLPFSDANFEDCFQRELNKIVGTPAFIAPELCHLGNSKRDFVTDGFKLDIWSLGVTLYCLLYNELPFFGENEFETYHKIIE</Hsp_hseq>
      <Hsp_midline>+T+ +Y +    G G FG V K      G+VVA+K IPK                               G     L N+   R EI     L++  +IV++++  ++   + + +VT++   GEL    +DD + LP+ +             ++I   +   L YLHS   +HRD+KP NILL  +  V KL DFG          F+ A   +     L  I GTP +++PEL        D        D+WS+G  LY L     PF+  + F+    II+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>91</Hit_num>
  <Hit_id>YDR247W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:956013:957398:1 gene:YDR247W transcript:YDR247W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VHS1 description:Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; VHS1 has a paralog, SKS1, that arose from the whole genome duplication [Source:SGD;Acc:S000002655]</Hit_def>
  <Hit_accession>YDR247W</Hit_accession>
  <Hit_len>461</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>7.53751e-14</Hsp_evalue>
      <Hsp_query-from>147</Hsp_query-from>
      <Hsp_query-to>725</Hsp_query-to>
      <Hsp_hit-from>9</Hsp_hit-from>
      <Hsp_hit-to>267</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>72</Hsp_gaps>
      <Hsp_align-len>262</Hsp_align-len>
      <Hsp_qseq>MEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFI-------------------------PKVGRSDKELRNLRR--EIDI-----------------------MRGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQILEDDGNLPEEQ--VREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSI-KGTPLYMSPELV-------EEKPYDH---------TADLWSMGCILYEL</Hsp_qseq>
      <Hsp_hseq>INNYLITSQIGEGAYGLVYRALDIRTDRQYAIKAVVQSYGVSKEADMGNDKIHKNSVKLQKKLAKLFKESKNVVRVPSIDLESIENMSEEDFKKLPHYKEISLHLRVHHHKNIVTIHEVLQSAVCTFIVMDYYPTDLFTSIVDNRHFVTNGLLVKKVFLQICSALNYCHEHGIYHCDIKPENLLLDTEDNVFLCDFGLS---TTSTYIKPNVCIGSSYYMPPERISFDGRVSSSKSGGHKLGKVCPSCNGDLWSLGIILINL</Hsp_hseq>
      <Hsp_midline>+  Y +   IGEG++G VY+     T +  A+K +                          K+ +  KE +N+ R   ID+                       +R   H NIV + +  ++     +V DY   +LF  + D+ +       V+++  Q+ SAL Y H H I H D+KP+N+LL     V LCDFG +   + +T +  ++  G+  YM PE +         K   H           DLWS+G IL  L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>92</Hit_num>
  <Hit_id>YNL020C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:595623:597539:-1 gene:YNL020C transcript:YNL020C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ARK1 description:Serine/threonine protein kinase; involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis; ARK1 has a paralog, PRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004965]</Hit_def>
  <Hit_accession>YNL020C</Hit_accession>
  <Hit_len>638</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>9.4783e-14</Hsp_evalue>
      <Hsp_query-from>162</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>24</Hsp_hit-from>
      <Hsp_hit-to>246</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>226</Hsp_align-len>
      <Hsp_qseq>VLEMIGEGSFGKVYKG-----RKRYTGQVVALKFIPKVGRSDK-ELRNLRREIDIMRGLQHPN-IVQMLDSFETDK-------EVVVVTDYAE-GELFQILED--DGNLPEEQVREIACQLVSALYYLHSHR--ILHRDMKPQNILLGKGGVVKLCDFGFARAM---SINTLVLTSIK------GTPLYMSPELVEE---KPYDHTADLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>IIKYLTSGGFAQVYSALINPPDPHSNSSVACLK---RVIVPDKPSLNTLRAEVDAMRLLKNNRYVVSYIDSHAAKAMLHNGSYEVFVLMEYCERGGLIDFMNTRLQNRLHEFEILQIMSQVTQGVAAMHALQPPLIHRDIKIENVLISANNEYKLCDFGSVCGIIRPPRNSQELSYVQQDILKNTTAQYRSPEMIDTFRGLPIDEKSDIWALGIFLYKLCYYTTPF</Hsp_hseq>
      <Hsp_midline>+++ +  G F +VY              V  LK   +V   DK  L  LR E+D MR L++   +V  +DS            EV V+ +Y E G L   +       L E ++ +I  Q+   +  +H+ +  ++HRD+K +N+L+      KLCDFG    +     N+  L+ ++       T  Y SPE+++     P D  +D+W++G  LY+L   T PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>93</Hit_num>
  <Hit_id>YHR135C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:372694:374310:-1 gene:YHR135C transcript:YHR135C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YCK1 description:Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform; shares redundant functions with Yck2p in morphogenesis, proper septin assembly, endocytic trafficking, and glucose sensing; stabilized by Sod1p binding in the presence of glucose and oxygen, causing glucose repression of respiratory metabolism; involved in the phosphorylation and regulation of glucose sensor Rgt2p; YCK1 has a paralog, YCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001177]</Hit_def>
  <Hit_accession>YHR135C</Hit_accession>
  <Hit_len>538</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>1.08725e-13</Hsp_evalue>
      <Hsp_query-from>156</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>69</Hsp_hit-from>
      <Hsp_hit-to>275</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>210</Hsp_align-len>
      <Hsp_qseq>YHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQILEDDG-NLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGV-----VKLCDFGFAR-------AMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>YKIGKKIGEGSFGVLFEGTNMINGVPVAIKFEPRKTEA-PQLRDEYKTYKILNGT--PNIPYAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRKFSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANNIHLIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGHLPW</Hsp_hseq>
      <Hsp_midline>Y + + IGEGSFG +++G     G  VA+KF P+   +  +LR+  +   I+ G   PNI       +     ++V D     L  + +  G     + V ++A Q+++ +  LH+H +++RD+KP N L+G+ G      + L DFG A+          I      S+ GT  YMS      +      D+ ++G + +    G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>94</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>1.79e-13</Hsp_evalue>
      <Hsp_query-from>147</Hsp_query-from>
      <Hsp_query-to>725</Hsp_query-to>
      <Hsp_hit-from>441</Hsp_hit-from>
      <Hsp_hit-to>646</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>210</Hsp_align-len>
      <Hsp_qseq>MEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFI-PKVGRSDKELRNLRREIDIMRGLQH---------PNIVQMLDSFETDKEVVVVTDYAE-GEL-----FQILEDDGNLPEEQVREIACQLVSALYYLH-SHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYEL</Hsp_qseq>
      <Hsp_hseq>FEKFTNVHSIGKGQFSTVYQVTFAQTNKKYAIKAIKPNKYNS---LKRILLEIKILNEVTNQITMDQEGKEYIIDYISSWKFQNSYYIMTELCENGNLDGFLQEQVIAKKKRLEDWRIWKIIVELSLALRFIHDSCHIVHLDLKPANVMITFEGNLKLGDFGMATHLPLEDKSFEN-EGDREYIAPEIISDCTYDYKADIFSLGLMIVEI</Hsp_hseq>
      <Hsp_midline> EK+  +  IG+G F  VY+     T +  A+K I P    S   L+ +  EI I+  + +           I+  + S++      ++T+  E G L      Q++     L + ++ +I  +L  AL ++H S  I+H D+KP N+++   G +KL DFG A  + +      + +G   Y++PE++ +  YD+ AD++S+G ++ E+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>95</Hit_num>
  <Hit_id>YLL019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:105686:107899:-1 gene:YLL019C transcript:YLL019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KNS1 description:Protein kinase involved in negative regulation of PolIII transcription; effector kinase of the TOR signaling pathway and phosphorylates Rpc53p to regulate ribosome and tRNA biosynthesis; member of the LAMMER family of protein kinases, which are serine/threonine kinases also capable of phosphorylating tyrosine residues; capable of autophosphorylation [Source:SGD;Acc:S000003942]</Hit_def>
  <Hit_accession>YLL019C</Hit_accession>
  <Hit_len>737</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>1.87686e-13</Hsp_evalue>
      <Hsp_query-from>153</Hsp_query-from>
      <Hsp_query-to>734</Hsp_query-to>
      <Hsp_hit-from>312</Hsp_hit-from>
      <Hsp_hit-to>540</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>43</Hsp_gaps>
      <Hsp_align-len>233</Hsp_align-len>
      <Hsp_qseq>KYHVLEMIGEGSFGKVYKG-RKRYTGQVVALKFIPKVGR----SDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQILEDDG--NLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILL---------------------------GKGGV-----VKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVG</Hsp_qseq>
      <Hsp_hseq>RFVVKDLLGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDRYREAAKTELRILQTILNNDPQGQFQCLL-LRECFDYKNHICLVTDLYGRSIYDFMCSNGIARFPGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENILICDETHIAQKLPLKTVQSLSKRRREASKGKRKILKNPEIKIIDFGSA---IFHYEYHPPVISTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVIG</Hsp_hseq>
      <Hsp_midline>++ V +++G+G+FGKV K    +Y    VA+K I  V R    +  ELR L+  ++     Q   ++ + + F+    + +VTD     ++  +  +G    P   ++ IA QL+ ++ +LH   I+H D+KP+NIL+                           GK  +     +K+ DFG A     +      +  T  Y +PE+V    +    D+WS+ C+L EL +G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>96</Hit_num>
  <Hit_id>YJL165C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:106894:109461:-1 gene:YJL165C transcript:YJL165C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HAL5 description:Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters; HAL5 has a paralog, KKQ8, that arose from the whole genome duplication [Source:SGD;Acc:S000003701]</Hit_def>
  <Hit_accession>YJL165C</Hit_accession>
  <Hit_len>855</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>6.22887e-13</Hsp_evalue>
      <Hsp_query-from>327</Hsp_query-from>
      <Hsp_query-to>734</Hsp_query-to>
      <Hsp_hit-from>601</Hsp_hit-from>
      <Hsp_hit-to>765</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>166</Hsp_align-len>
      <Hsp_qseq>PNIVQMLDSFETDKEVVVVTDY-AEGELFQILEDDGNLPEEQVR--------------------EIAC---QLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFG----FARAMSINTLVLTSIKGTPLYMSP-ELVEEKPYD-HTADLWSMGCILYELFVG</Hsp_qseq>
      <Hsp_hseq>PNILKILDLMEYSNSFVEVMEFCASGDLYSLLTRN-NISNESNNGSSRLIQTVKEGSGSPLHPLEADCFMKQLLNGVQYMHDHGIAHCDLKPENILFQPNGLLKICDFGTSSVFQTAWEKHVHFQSGAMGSEPYVAPEEFIRDAEYDPRLVDCWSCGIVYCTMVMG</Hsp_hseq>
      <Hsp_midline>PNI+++LD  E     V V ++ A G+L+ +L  + N+  E                       E  C   QL++ + Y+H H I H D+KP+NIL    G++K+CDFG    F  A   +    +   G+  Y++P E + +  YD    D WS G +   + +G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>97</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>1.30972e-12</Hsp_evalue>
      <Hsp_query-from>150</Hsp_query-from>
      <Hsp_query-to>731</Hsp_query-to>
      <Hsp_hit-from>36</Hsp_hit-from>
      <Hsp_hit-to>280</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>57</Hsp_gaps>
      <Hsp_align-len>248</Hsp_align-len>
      <Hsp_qseq>EKYHVLEMIGEGSFGKVYKGRKRY------------------------------TGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSF--ETDKEVVVVTDYAEGELFQILEDDG----NLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGG-----------------VVKLCDFGFARAMSINTLVLTSIKGTPLYMSPE-LVEEKPYDHTADLWSMGCILYELFV</Hsp_qseq>
      <Hsp_hseq>DRYQLIEKLGAGSFGCVTLAKAQFPLSNILGKQHDIRGTLMDQPKNGHQNYITKTQGVVAIKTMMTKLHTLQDYTRVREIKFILAIPANDHLIQIFEVFIDSENYQLHIVMECMEQNLYQMMKHRRRRVFSIP--SLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVE-NKNPYTAYVSTRWYRSPEILLRSGYYSKPLDIWAFGCVAVEVTV</Hsp_hseq>
      <Hsp_midline>++Y ++E +G GSFG V   + ++                              T  VVA+K +     + ++   +R    I+    + +++Q+ + F    + ++ +V +  E  L+Q+++       ++P   ++ I  Q+++ L ++H H   HRD+KP+NIL+                     V+KL DFG AR +  N    T+   T  Y SPE L+    Y    D+W+ GC+  E+ V</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>98</Hit_num>
  <Hit_id>YDL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:424209:425732:1 gene:YDL017W transcript:YDL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC7 description:DDK (Dbf4-dependent kinase) catalytic subunit; required for origin firing and replication fork progression in mitotic S phase through phosphorylation of Mcm2-7p complexes and Cdc45p; kinase activity correlates with cyclical DBF4 expression; required for pre-meiotic DNA replication, meiotic DSB formation, recruitment of monopolin complex to kinetochores during meiosis I, regulation of meiosis-specific Ndt80p; mutation complemented by human CDC7 and DBF4 co-expression [Source:SGD;Acc:S000002175]</Hit_def>
  <Hit_accession>YDL017W</Hit_accession>
  <Hit_len>507</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>2.19629e-12</Hsp_evalue>
      <Hsp_query-from>129</Hsp_query-from>
      <Hsp_query-to>593</Hsp_query-to>
      <Hsp_hit-from>24</Hsp_hit-from>
      <Hsp_hit-to>188</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>173</Hsp_align-len>
      <Hsp_qseq>HFWPRTMEKYHVLEMIGEGSFGKVYKGRK--------------RYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNIL----LGKGGVVKLCDFGFARA</Hsp_qseq>
      <Hsp_hseq>HDLPGIENEYKLIDKIGEGTFSSVYKAKDITGKITKKFASHFWNYGSNYVALKKI-YVTSSPQRIYNELNLLYIMTG--SSRVAPLCDAKRVRDQVIAVLPYYPHEEFRTFYRD--LPIKGIKKYIWELLRALKFVHSKGIIHRDIKPTNFLFNLELGRGVLV---DFGLAEA</Hsp_hseq>
      <Hsp_midline>H  P    +Y +++ IGEG+F  VYK +                Y    VALK I  V  S + + N    + IM G     +  + D+     +V+ V  Y   E F+    D  LP + +++   +L+ AL ++HS  I+HRD+KP N L    LG+G +V   DFG A A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>99</Hit_num>
  <Hit_id>YBR059C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:356861:360187:-1 gene:YBR059C transcript:YBR059C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AKL1 description:Ser-Thr protein kinase; member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization [Source:SGD;Acc:S000000263]</Hit_def>
  <Hit_accession>YBR059C</Hit_accession>
  <Hit_len>1108</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>2.35559e-12</Hsp_evalue>
      <Hsp_query-from>153</Hsp_query-from>
      <Hsp_query-to>797</Hsp_query-to>
      <Hsp_hit-from>34</Hsp_hit-from>
      <Hsp_hit-to>285</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>63</Hsp_gaps>
      <Hsp_align-len>265</Hsp_align-len>
      <Hsp_qseq>KYHVLEMIGEGSFGKVYKGR-KRYTGQVVALKFIP-KVG----------RSDKELRNLRREIDIMRGLQ-HPNIVQMLDSFETDK-------EVVVV------------------TDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFG-----FARAMSINTLVLTS----IKGTPLYMSPELVEEK---PYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKDPV</Hsp_qseq>
      <Hsp_hseq>KVEVVNYLAEGGFAQIYVVKFLEYLNEFDNTASVPLKIGDVACLKRVLVQDENGLNEMRNEVEVMKKLKGAPNIVQYFDSNASRRRDGVQGFEVLLLMELCPNKSLLDYMNQRLSTKLTEAEIVKIMYD-----------VALS-ISQMHYLPV-SLIHRDIKIENVLVDAKNNFKLADFGSTSTCFPIVTTHQDIALLTQNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGVFLYKLLFFTTPFEMTGQFAILHSKYEFPV</Hsp_hseq>
      <Hsp_midline>K  V+  + EG F ++Y  +   Y  +      +P K+G          + +  L  +R E+++M+ L+  PNIVQ  DS  + +       EV+++                  T   E E+ +I+ D           +A   +S ++YL    ++HRD+K +N+L+      KL DFG     F    +   + L +    +  TP Y SPE+++     P +  +D+W++G  LY+L   T PF     F ++    + PV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>100</Hit_num>
  <Hit_id>YKL168C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:131288:133462:-1 gene:YKL168C transcript:YKL168C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KKQ8 description:Putative serine/threonine protein kinase with unknown cellular role; KKQ8 has a paralog, HAL5, that arose from the whole genome duplication [Source:SGD;Acc:S000001651]</Hit_def>
  <Hit_accession>YKL168C</Hit_accession>
  <Hit_len>724</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>3.87728e-12</Hsp_evalue>
      <Hsp_query-from>327</Hsp_query-from>
      <Hsp_query-to>734</Hsp_query-to>
      <Hsp_hit-from>494</Hsp_hit-from>
      <Hsp_hit-to>640</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>147</Hsp_align-len>
      <Hsp_qseq>PNIVQMLDSFETDKEVVVVTDYA-EGELFQILEDDGNLPEE-QVREIAC---QLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFG----FARAMSINTLVLTSIKGTPLYMSP-ELVEEKPYD-HTADLWSMGCILYELFVG</Hsp_qseq>
      <Hsp_hseq>PNILNVFDILEDSSSFIEVMEFCPAGDLYGMLVGKSKLKGRLHPLEADCFMKQLLHGVKFMHDHGIAHCDLKPENILFYPHGLLKICDFGTSSVFQTAWERRVHAQKGIIGSEPYVAPEEFVDGEYYDPRLIDCWSCGVVYITMILG</Hsp_hseq>
      <Hsp_midline>PNI+ + D  E     + V ++   G+L+ +L     L       E  C   QL+  + ++H H I H D+KP+NIL    G++K+CDFG    F  A          I G+  Y++P E V+ + YD    D WS G +   + +G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>101</Hit_num>
  <Hit_id>YJR059W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:545787:548243:1 gene:YJR059W transcript:YJR059W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK2 description:Serine/threonine protein kinase; involved in regulation of ion transport across plasma membrane; carboxyl terminus is essential for glucose-dependent Pma1p activation via phosphorylation of Pma1p-Ser899; enhances spermine uptake; PTK2 has a paralog, PTK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003820]</Hit_def>
  <Hit_accession>YJR059W</Hit_accession>
  <Hit_len>818</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>2.16223e-11</Hsp_evalue>
      <Hsp_query-from>132</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>236</Hsp_hit-from>
      <Hsp_hit-to>482</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>250</Hsp_align-len>
      <Hsp_qseq>FWPRTMEKYHVL-----------EMIGEGSFGKVYKGRKRYTGQ-VVALKFIPKVGRSDKE--LRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEG----------ELFQILEDDG--NLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTS-------IKGTPLYMSPELVE-----------EKPYDHTA-DLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>FLPEDMKQYSVHLTDNFVFDTDNKPIGSGGSSEVRKVKSSYRQKDVYALKKLNMIYHESPEKFYKRCSKEFIIAKHLSH--NVHITNTFYLLK-VPTTTYTTRGWGFIMELGVKDLFQLMERTGWKNVPFNEKYCLFKQVAQGIKFCHDNGIAHRDLKPENVLISKEGICKLTDFGISDWYHVIPHDYTSPVKTCQGMIGSPPYTPPEVMYFDAKKHYPEKFQKPYNPLAMDSYALGIMLITMINNIIPF</Hsp_hseq>
      <Hsp_midline>F P  M++Y V            + IG G   +V K +  Y  + V ALK +  +     E   +   +E  I + L H   V + ++F   K V   T    G          +LFQ++E  G  N+P  +   +  Q+   + + H + I HRD+KP+N+L+ K G+ KL DFG +    +     TS       + G+P Y  PE++            +KPY+  A D +++G +L  +     PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>102</Hit_num>
  <Hit_id>YKL198C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:68232:70220:-1 gene:YKL198C transcript:YKL198C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK1 description:Putative serine/threonine protein kinase; regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein; PTK1 has a paralog, PTK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001681]</Hit_def>
  <Hit_accession>YKL198C</Hit_accession>
  <Hit_len>662</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>3.04417e-10</Hsp_evalue>
      <Hsp_query-from>168</Hsp_query-from>
      <Hsp_query-to>764</Hsp_query-to>
      <Hsp_hit-from>200</Hsp_hit-from>
      <Hsp_hit-to>429</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>230</Hsp_align-len>
      <Hsp_qseq>EMIGEGSFGKVYKGRKRYTGQ-VVALKFIPKVGRSDKE--LRNLRREIDIMRGLQHPN-------IVQMLDSFETDKEVVVVTDYAEGELFQILEDDG--NLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTS-------IKGTPLYMSPELV-----------EEKPYDHTA-DLWSMGCILYELFVGTPPFYTNSIF</Hsp_qseq>
      <Hsp_hseq>KTIGWGGSCEVRKIRSKYRKKDVFALKKLNMIYNETPEKFYKRCSKEFIIAKQLSHHVHITNTFLLVKVPTTVYTTRGWGFVMELGLRDLFAMIQKSGWRSVALAEKFCIFKQVACGVKFCHDQGIAHRDLKPENVLLSPDGVCKLTDFGISDWYHTDPHDLSSPVKKCAGMIGSPPYAPPEVMFYDSKKHYDTELQQPYDPRALDCYGLGIILMTLVNNVIPFLESCSF</Hsp_hseq>
      <Hsp_midline>+ IG G   +V K R +Y  + V ALK +  +     E   +   +E  I + L H         +V++  +  T +    V +    +LF +++  G  ++   +   I  Q+   + + H   I HRD+KP+N+LL   GV KL DFG +     +   L+S       + G+P Y  PE++            ++PYD  A D + +G IL  L     PF  +  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>103</Hit_num>
  <Hit_id>YPL204W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:164276:165760:1 gene:YPL204W transcript:YPL204W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRR25 description:Conserved casein kinase; regulates diverse events including: vesicular traffic, DNA repair, the CVT pathway, monopolar attachment of sister kinetochores at meiosis I, and ribosomal subunit biogenesis; monopolin subunit; binds the RNAPII CTD; phosphorylates COPII coat subunits; interacts with Sit4p phosphatase; antagonizes calcineurin signaling, reducing nuclear accumulation of Crz1p; phosphorylates Dsn1p, the kinetochore receptor for monopolin; homolog of mammalian CK1delta [Source:SGD;Acc:S000006125]</Hit_def>
  <Hit_accession>YPL204W</Hit_accession>
  <Hit_len>494</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>3.2699e-09</Hsp_evalue>
      <Hsp_query-from>141</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>4</Hsp_hit-from>
      <Hsp_hit-to>213</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>218</Hsp_align-len>
      <Hsp_qseq>RTMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRS---DKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLG---KGGVVKLCDFGFARAM-SINTLVL------TSIKGTPLYMSPEL---VEEKPYDHTADLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>RVGRKFRIGRKIGSGSFGDIYHGTNLISGEEVAIKLESIRSRHPQLDYESRVYRY---LSGGVGIPFIRWFGREGEYNAMVIDLLGPSLEDLFNYCHRRFSF--KTVIMLALQMFCRIQYIHGRSFIHRDIKPDNFLMGVGRRGSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLTGTARYASVNTHLGIEQSRRD---DLESLGYVLIYFCKGSLPW</Hsp_hseq>
      <Hsp_midline>R   K+ +   IG GSFG +Y G    +G+ VA+K      R    D E R  R    +  G+  P I       E +  V+ +   +  +LF       +   + V  +A Q+   + Y+H    +HRD+KP N L+G   +G  V + DFG ++     NT          S+ GT  Y S      +E+   D   DL S+G +L     G+ P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>104</Hit_num>
  <Hit_id>YBR097W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:436951:441315:1 gene:YBR097W transcript:YBR097W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VPS15 description:Serine/threonine protein kinase involved in vacuolar protein sorting; functions as a membrane-associated complex with Vps34p; active form recruits Vps34p to the Golgi membrane; interacts with the GDP-bound form of Gpa1p; myristoylated; a fraction is localized, with Vps34p, to nuclear pores at nucleus-vacuole junctions and may facilitate transcription elongation for genes positioned at the nuclear periphery [Source:SGD;Acc:S000000301]</Hit_def>
  <Hit_accession>YBR097W</Hit_accession>
  <Hit_len>1454</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>6.29591e-09</Hsp_evalue>
      <Hsp_query-from>147</Hsp_query-from>
      <Hsp_query-to>767</Hsp_query-to>
      <Hsp_hit-from>24</Hsp_hit-from>
      <Hsp_hit-to>248</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>227</Hsp_align-len>
      <Hsp_qseq>MEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFI-PKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDF-GFARAMSIN-------TLVLTSIKGTPLYMSPELVEEKPYD----------HTADLWSMGCILYELFV-GTPPFYTNSIFQ</Hsp_qseq>
      <Hsp_hseq>LEEVHYVSQLNSSRFLKTCKALDP-NGEIVIKVFIKPKDQYSLRPFLQRIRAQSFKLG-QLPHVLNYSKLIETNRAGYMIRQHLKNNLYDRLSLRPYLQDIELKFIAFQLLNALKDIHNLNIVHGDIKTENILVTSWNWCILTDFAAFIKPVYLPEDNPGEFLFYFDTSKRRTCYLAPERFNSKLYQDGKSNNGRLTKEMDIFSLGCVIAEIFAEGRPIFNLSQLFK</Hsp_hseq>
      <Hsp_midline>+E+ H +  +    F K  K      G++V   FI PK   S +      R      G Q P+++      ET++   ++  + +  L+  L     L + +++ IA QL++AL  +H+  I+H D+K +NIL+       L DF  F + + +             + K    Y++PE    K Y              D++S+GC++ E+F  G P F  + +F+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>105</Hit_num>
  <Hit_id>YFL029C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:78055:79161:-1 gene:YFL029C transcript:YFL029C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CAK1 description:Cyclin-dependent kinase-activating kinase; required for passage through the cell cycle; phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases [Source:SGD;Acc:S000001865]</Hit_def>
  <Hit_accession>YFL029C</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>1.31432e-08</Hsp_evalue>
      <Hsp_query-from>468</Hsp_query-from>
      <Hsp_query-to>728</Hsp_query-to>
      <Hsp_hit-from>139</Hsp_hit-from>
      <Hsp_hit-to>238</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>101</Hsp_align-len>
      <Hsp_qseq>QLVSALYYLHSHRILHRDMKPQNILLGKGGV-----VKLCDFGFARAMSINTLV--------LTSIKGTPLYMSPE-LVEEKPYDHTADLWSMGCILYELF</Hsp_qseq>
      <Hsp_hseq>QMVEGIAFLHENKIIHRDIKPQNIMLTNNTSTVSPKLYIIDFGISYDMANNSQTSAEPMDSKVTDI-STGIYKAPEVLFGVKCYDGGVDVWSLLIIISQWF</Hsp_hseq>
      <Hsp_midline>Q+V  + +LH ++I+HRD+KPQNI+L          + + DFG +  M+ N+          +T I  T +Y +PE L   K YD   D+WS+  I+ + F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>106</Hit_num>
  <Hit_id>YHR079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:258244:261591:-1 gene:YHR079C transcript:YHR079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IRE1 description:Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; role in homeostatic adaptation to ER stress; Kar2p binds inactive Ire1p and releases from it upon ER stress [Source:SGD;Acc:S000001121]</Hit_def>
  <Hit_accession>YHR079C</Hit_accession>
  <Hit_len>1115</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>1.57035e-08</Hsp_evalue>
      <Hsp_query-from>168</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>678</Hsp_hit-from>
      <Hsp_hit-to>921</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>69</Hsp_gaps>
      <Hsp_align-len>253</Hsp_align-len>
      <Hsp_qseq>EMIGEGSFGKV-YKGRKRYTGQVVALK--FIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQILEDDGNLPEEQVR--------EIACQLVSALYYLHSHRILHRDMKPQNILLGKGG-------------VVKLCDFGFARAM----SINTLVLTSIKGTPLYMSPELVEEKP-----------------------YD--------HTADLWSMGCILYELFV-GTPPF</Hsp_qseq>
      <Hsp_hseq>KILGYGSSGTVVFQGS--FQGRPVAVKRMLIDFCDIALMEIKLLTESDD------HPNVIRYYCSETTDRFLYIALELCNLNL-QDLVESKNVSDENLKLQKEYNPISLLRQIASGVAHLHSLKIIHRDLKPQNILVSTSSRFTADQQTGAENLRILISDFGLCKKLDSGQSSFRTNLNNPSGTSGWRAPELLEESNNLQCQVETEHSSSRHTVVSSDSFYDPFTKRRLTRSIDIFSMGCVFYYILSKGKHPF</Hsp_hseq>
      <Hsp_midline>+++G GS G V ++G   + G+ VA+K   I     +  E++ L    D      HPN+++   S  TD+ + +  +     L Q L +  N+ +E ++         +  Q+ S + +LHS +I+HRD+KPQNIL+                  + + DFG  + +    S     L +  GT  + +PEL+EE                         YD         + D++SMGC+ Y +   G  PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>107</Hit_num>
  <Hit_id>YKL171W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:127475:130261:1 gene:YKL171W transcript:YKL171W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NNK1 description:Protein kinase; implicated in proteasome function; interacts with TORC1, Ure2 and Gdh2; overexpression leads to hypersensitivity to rapamycin and nuclear accumulation of Gln3; epitope-tagged protein localizes to the cytoplasm [Source:SGD;Acc:S000001654]</Hit_def>
  <Hit_accession>YKL171W</Hit_accession>
  <Hit_len>928</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>1.86238e-08</Hsp_evalue>
      <Hsp_query-from>12</Hsp_query-from>
      <Hsp_query-to>587</Hsp_query-to>
      <Hsp_hit-from>401</Hsp_hit-from>
      <Hsp_hit-to>607</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>208</Hsp_align-len>
      <Hsp_qseq>CRHGYCDVSSSESKLPSRSCVKYITAAPFKNSSNSQTWEHFWPRTMEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLD-SFETDKEVVVVTD-YAEGELFQILED-----DGNLP-EEQVRE---IACQLVSALYYLHSHRILHRDMKPQNILLGKGG-----VVKLCDFGFA</Hsp_qseq>
      <Hsp_hseq>SRHGSIASQFLSSFSPSMTSIAKMNSNPLSGSAGGSARPDDKGMEILGHRLGKIIGFGAWGIIRECFDIETGVGRVIKIVKFKGHQNIK-KHVLREVAIWRTLKHNRILPLLDWKLDDNYAMYCLTERINDGTLYDLVISWDEFKRSKIPFAERCRLTIFLSLQLLSALKYMHSKTIVHGDIKLENCLLQKEGKKSDWKVFLCDFGMS</Hsp_hseq>
      <Hsp_midline> RHG        S  PS + +  + + P   S+            +  + + ++IG G++G + +     TG    +K +   G  + + +++ RE+ I R L+H  I+ +LD   + +  +  +T+   +G L+ ++          +P  E+ R    ++ QL+SAL Y+HS  I+H D+K +N LL K G      V LCDFG +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>108</Hit_num>
  <Hit_id>YGL083W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:353058:355472:1 gene:YGL083W transcript:YGL083W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCY1 description:Putative kinase; suppressor of GTPase mutant; similar to bovine rhodopsin kinase; may have a role in intracellular sterol transport [Source:SGD;Acc:S000003051]</Hit_def>
  <Hit_accession>YGL083W</Hit_accession>
  <Hit_len>804</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>1.79365e-06</Hsp_evalue>
      <Hsp_query-from>255</Hsp_query-from>
      <Hsp_query-to>734</Hsp_query-to>
      <Hsp_hit-from>68</Hsp_hit-from>
      <Hsp_hit-to>256</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>191</Hsp_align-len>
      <Hsp_qseq>KVGRSDKELRN-----LRREIDIMRGLQHPNIVQMLDSFET-DKEVVVVTDYAEGELFQILEDDGNLPEEQ------------VREIACQLVSALYYLHSH-RILHRDMKPQNILLGKGGVVKLCDFGFARAMSINT------LVLTSIKGTPL------YMSPELVEEKPYDHTADLWSMGCILYELFVG</Hsp_qseq>
      <Hsp_hseq>KSGSRDKVLIQEAYEILRNQANNLAKLKHPNILTLIEPLEEHSKNFMFVTEFVTSSLETVFRETDD--EEQNFLQGHVKDNIVVQRGILQLVNALDFVHNRASFVHLNIQPRAIFINENSDWKISGLGYLVKIPPGTNTSEYFLPQYDPRVPPFMHLQLNYTAPEIVFENTLTFKNDYFSLGLLIYFLYTG</Hsp_hseq>
      <Hsp_midline>K G  DK L       LR + + +  L+HPNI+ +++  E   K  + VT++    L  +  +  +  EEQ            V+    QLV+AL ++H+    +H +++P+ I + +    K+   G+   +   T      L     +  P       Y +PE+V E       D +S+G ++Y L+ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>109</Hit_num>
  <Hit_id>YER123W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:404813:406387:1 gene:YER123W transcript:YER123W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YCK3 description:Palmitoylated vacuolar membrane-localized casein kinase I isoform; negatively regulates vacuole fusion during hypertonic stress via phosphorylation of Vps41p; shares essential functions with Hrr25p; regulates vesicle fusion in AP-3 pathway [Source:SGD;Acc:S000000925]</Hit_def>
  <Hit_accession>YER123W</Hit_accession>
  <Hit_len>524</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.9802</Hsp_bit-score>
      <Hsp_score>110</Hsp_score>
      <Hsp_evalue>3.02783e-06</Hsp_evalue>
      <Hsp_query-from>156</Hsp_query-from>
      <Hsp_query-to>746</Hsp_query-to>
      <Hsp_hit-from>14</Hsp_hit-from>
      <Hsp_hit-to>253</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>57</Hsp_gaps>
      <Hsp_align-len>247</Hsp_align-len>
      <Hsp_qseq>YHVLEMIGEGSFGKVYKGR------KRYTG-----------QVVALKFIPKVGRSDK-ELRNLRREIDIMRGLQHPNIVQMLDSFETDKE---VVVVTDYAEGELFQILEDDG-NLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGK-------GGVVKLC--------------DFGFAR-------AMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPF</Hsp_qseq>
      <Hsp_hseq>YAVGPKIGEGSFGVIFEGENILHSCQAQTGSKRDSSIIMANEPVAIKFEPR--HSDAPQLRDEFRAYRILNGC-----VGIPHAYYFGQEGMHNILIIDLLGPSLEDLFEWCGRKFSVKTTCMVAKQMIDRVRAIHDHDLIYRDIKPDNFLISQYQRISPEGKVIKSCASSSNNDPNLIYMVDFGMAKQYRDPRTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPW</Hsp_hseq>
      <Hsp_midline>Y V   IGEGSFG +++G       +  TG           + VA+KF P+   SD  +LR+  R   I+ G      V +  ++   +E    +++ D     L  + E  G     +    +A Q++  +  +H H +++RD+KP N L+ +       G V+K C              DFG A+          I      S+ GT  YMS      +      DL S+G + +    G+ P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>610755288</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052268-RA transcript Note:&quot;Similar to Bicdl1 BICD family-like cargo adapter 1 (Mus musculus)&quot; offset:635 AED:0.50 eAED:0.60 QI:635|0|0.12|0.25|1|1|8|0|492</Iteration_query-def>
  <Iteration_query-len>2114</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1380237269</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052269-RA transcript Note:&quot;Similar to Tlr2 Toll-like receptor 2 (Mus musculus)&quot; offset:0 AED:0.27 eAED:0.27 QI:0|0|0|0.5|1|1|4|0|622</Iteration_query-def>
  <Iteration_query-len>1869</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1201806109</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052270-RA transcript Note:&quot;Similar to Tlr2 Toll-like receptor 2 (Mus musculus)&quot; offset:0 AED:0.17 eAED:0.17 QI:0|0|0|1|1|0.5|2|0|362</Iteration_query-def>
  <Iteration_query-len>1089</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>629263024</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052271-RA transcript Note:&quot;Similar to RPLP0 60S acidic ribosomal protein P0 (Rana sylvatica)&quot; offset:1694 AED:0.15 eAED:0.15 QI:1694|1|1|1|0.83|0.71|7|0|314</Iteration_query-def>
  <Iteration_query-len>2639</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YLR340W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:805887:806825:1 gene:YLR340W transcript:YLR340W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RPP0 description:Conserved ribosomal protein P0 of the ribosomal stalk; involved in interaction between translational elongation factors and the ribosome; phosphorylated on serine 302; homologous to mammalian ribosomal protein LP0 and bacterial L10 [Source:SGD;Acc:S000004332]</Hit_def>
  <Hit_accession>YLR340W</Hit_accession>
  <Hit_len>312</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>300.827</Hsp_bit-score>
      <Hsp_score>769</Hsp_score>
      <Hsp_evalue>1.49407e-95</Hsp_evalue>
      <Hsp_query-from>1722</Hsp_query-from>
      <Hsp_query-to>2636</Hsp_query-to>
      <Hsp_hit-from>8</Hsp_hit-from>
      <Hsp_hit-to>312</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>164</Hsp_identity>
      <Hsp_positive>228</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>305</Hsp_align-len>
      <Hsp_qseq>KSNYFLKIIQLLEDFPKCFIVGADNVGSKQMQQIRMSLRGKAVVLMGKNTMMRKAIRGHLEKNPALERVLPYIRGNVGFVFTKEDLAEIRDMLLANKVPASARAGGLAPCDVMVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKAGDKVGASEATLLNMLNISPFTFGLHILQVYDNGSIYSPDVLDITEDDLRKRFLEGVRNVASVCLQIGYPTVASIPHSIVNGYKRVLAIAVETNYSFPLADKVKAFLADPSAFVTXXXXXXXXXXXXXXXXXXXXXXXXXXXDDDMGFGLFD</Hsp_qseq>
      <Hsp_hseq>KAEYFAKLREYLEEYKSLFVVGVDNVSSQQMHEVRKELRGRAVVLMGKNTMVRRAIRGFLSDLPDFEKLLPFVKGNVGFVFTNEPLTEIKNVIVSNRVAAPARAGAVAPEDIWVRAVNTGMEPGKTSFFQALGVPTKIARGTIEIVSDVKVVDAGNKVGQSEASLLNLLNISPFTFGLTVVQVYDNGQVFPSSILDITDEELVSHFVSAVSTIASISLAIGYPTLPSVGHTLINNYKDLLAVAIAASYHYPEIEDLVDRIENPEKYAAAAPAATSAASGDAAPAEEAAAEEEEESDDDMGFGLFD</Hsp_hseq>
      <Hsp_midline>K+ YF K+ + LE++   F+VG DNV S+QM ++R  LRG+AVVLMGKNTM+R+AIRG L   P  E++LP+++GNVGFVFT E L EI++++++N+V A ARAG +AP D+ V A NTG+ P KTSFFQALG+ TKI+RGTIEI+SDV+++ AG+KVG SEA+LLN+LNISPFTFGL ++QVYDNG ++   +LDIT+++L   F+  V  +AS+ L IGYPT+ S+ H+++N YK +LA+A+  +Y +P  + +   + +P  +  AAP A +AA   AA  E+    EEEE DDDMGFGLFD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YLR339C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:805784:806335:-1 gene:YLR339C transcript:YLR339C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the essential gene RPP0 [Source:SGD;Acc:S000004331]</Hit_def>
  <Hit_accession>YLR339C</Hit_accession>
  <Hit_len>183</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.4261</Hsp_bit-score>
      <Hsp_score>215</Hsp_score>
      <Hsp_evalue>3.14317e-20</Hsp_evalue>
      <Hsp_query-from>1754</Hsp_query-from>
      <Hsp_query-to>2149</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>132</Hsp_hit-to>
      <Hsp_query-frame>-2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>132</Hsp_align-len>
      <Hsp_qseq>MVPLEILVVMPRAWKKEVFSGPSPVFCAGTITSHGARPPARAEAGTXXXXXXXXXXXXXXLVKTNPTFPRMYGNTLSSAGFFSR*PRMALRIMVFLPMSTTAFPRNDMRICCICLEPTLSAPTMKHFGKSSR</Hsp_qseq>
      <Hsp_hseq>MVPLAILVGTPKAWKKEVLPGSIPVLTALTQMSSGATAPALAGAATLLETITFLISVNGSLVKTKPTLPLTKGNNFSKSGKSDKKPLMALLTMVFLPIKTTALPLNSFLTSCICWEETLSTPTTNKDLYSSK</Hsp_hseq>
      <Hsp_midline>MVPL ILV  P+AWKKEV  G  PV  A T  S GA  PA A A TLL      IS   SLVKT PT P   GN  S +G   + P MAL  MVFLP+ TTA P N     CIC E TLS PT      SS+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YKL009W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:426242:426952:1 gene:YKL009W transcript:YKL009W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRT4 description:Protein involved in mRNA turnover and ribosome assembly; required at post-transcriptional step for efficient retrotransposition; localizes to the nucleolus [Source:SGD;Acc:S000001492]</Hit_def>
  <Hit_accession>YKL009W</Hit_accession>
  <Hit_len>236</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>1.40544e-08</Hsp_evalue>
      <Hsp_query-from>1722</Hsp_query-from>
      <Hsp_query-to>2285</Hsp_query-to>
      <Hsp_hit-from>23</Hsp_hit-from>
      <Hsp_hit-to>225</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>208</Hsp_align-len>
      <Hsp_qseq>KSNYFLKIIQLLEDFPKCFIVGADNVGSKQMQQIRMSLRGKAVVLMGKNTMMRKAI--RGHLEKNPALERVLPYIRGNVGFVFTKEDLAEIRDMLLA----------NKVPAS--------ARAGGLAPCDVMVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKAGDKVGASEATLLNMLNISPFTFGLHILQVYDNGS</Hsp_qseq>
      <Hsp_hseq>KERIFDEVREALDTYRYVWVLHLDDVRTPVLQEIRTSWAGSKLI-MGKRKVLQKALGEKREEEYKENLYQLSKLCSGVTGLLFTDEDVNTVKEYFKSYVRSDYSRPNTKAPLTFTIPEGIVYSRGGQIPAEEDVPMIHS-LEPTMRNKFE---IPTKIKAGKITIDSPYLVCTEGEKLDVRQALILKQFGIAASEFKVKVSAYYDNDS</Hsp_hseq>
      <Hsp_midline>K   F ++ + L+ +   +++  D+V +  +Q+IR S  G  ++ MGK  +++KA+  +   E    L ++     G  G +FT ED+  +++   +           K P +           GG  P +  VP  ++ L P   + F+   I TKI  G I I S   +   G+K+   +A +L    I+   F + +   YDN S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1770735527</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052272-RA transcript Note:&quot;Similar to CLDN6 Claudin-6 (Homo sapiens)&quot; offset:0 AED:0.46 eAED:0.46 QI:0|-1|0|1|-1|1|1|0|201</Iteration_query-def>
  <Iteration_query-len>606</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>85</Statistics_hsp-len>
      <Statistics_eff-space>275308839</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052273-RA transcript Note:&quot;Protein of unknown function&quot; offset:1632 AED:0.22 eAED:0.22 QI:1632|1|0.8|1|0.25|0.2|5|0|152</Iteration_query-def>
  <Iteration_query-len>2091</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1370560667</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0041659-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.48 eAED:1.00 QI:0|0|0|0.33|1|1|3|0|247</Iteration_query-def>
  <Iteration_query-len>744</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDL019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:417663:421514:-1 gene:YDL019C transcript:YDL019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:OSH2 description:Member of an oxysterol-binding protein family with seven members; in S. cerevisiae, family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; contains FFAT motif; interacts with ER anchor Scs2p at patches at the plasma membrane and at the nuclear envelope; regulated by sterol binding; OSH2 has a paralog, SWH1, that arose from the whole genome duplication [Source:SGD;Acc:S000002177]</Hit_def>
  <Hit_accession>YDL019C</Hit_accession>
  <Hit_len>1283</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>2.12231e-14</Hsp_evalue>
      <Hsp_query-from>263</Hsp_query-from>
      <Hsp_query-to>541</Hsp_query-to>
      <Hsp_hit-from>287</Hsp_hit-from>
      <Hsp_hit-to>384</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>98</Hsp_align-len>
      <Hsp_qseq>SGPDTYKGWLFKWTNYIKGYQKRWFVLS-NGLLSYYSLVMQVRLIVGTINLAGA--YIDTEDSCNIVVSNG--GTQTYHLKASSEVERQRWVTALELA</Hsp_qseq>
      <Hsp_hseq>SKPPTYKGFLKKWTNFAHGYKLRWFILSGDGNLSYYKDQSHVDRPRGTLKVSTCRLHIDSSEKLNFELLGGITGTTRWRLKGNHPIETTRWVNAIQSA</Hsp_hseq>
      <Hsp_midline>S P TYKG+L KWTN+  GY+ RWF+LS +G LSYY     V    GT+ ++    +ID+ +  N  +  G  GT  + LK +  +E  RWV A++ A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YAR042W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:192619:196185:1 gene:YAR042W transcript:YAR042W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWH1 description:Protein similar to mammalian oxysterol-binding protein; contains ankyrin repeats and FFAT motif; interacts with ER anchor Scs2p at the nucleus-vacuole junction; regulated by sterol binding; SWH1 has a paralog, OSH2, that arose from the whole genome duplication [Source:SGD;Acc:S000000081]</Hit_def>
  <Hit_accession>YAR042W</Hit_accession>
  <Hit_len>1188</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>7.51861e-13</Hsp_evalue>
      <Hsp_query-from>275</Hsp_query-from>
      <Hsp_query-to>541</Hsp_query-to>
      <Hsp_hit-from>283</Hsp_hit-from>
      <Hsp_hit-to>377</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>95</Hsp_align-len>
      <Hsp_qseq>TYKGWLFKWTNYIKGYQKRWFVL-SNGLLSYYSLVMQVR-LIVGTINLAGAYIDTEDS----CNIVVSNGGTQTYHLKASSEVERQRWVTALELA</Hsp_qseq>
      <Hsp_hseq>TYKGYLKKWTNFAQGYKLRWFILSSDGKLSYYIDQADTKNACRGSLNMSSCSLHLDSSEKLKFEIIGGNNGVIRWHLKGNHPIETNRWVWAIQGA</Hsp_hseq>
      <Hsp_midline>TYKG+L KWTN+ +GY+ RWF+L S+G LSYY      +    G++N++   +  + S      I+  N G   +HLK +  +E  RWV A++ A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>87</Statistics_hsp-len>
      <Statistics_eff-space>376718587</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052274-RA transcript Note:&quot;Similar to Osbp Oxysterol-binding protein 1 (Mus musculus)&quot; offset:0 AED:0.05 eAED:0.05 QI:0|0.6|0.81|0.90|1|0.90|11|3903|553</Iteration_query-def>
  <Iteration_query-len>5565</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDL019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:417663:421514:-1 gene:YDL019C transcript:YDL019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:OSH2 description:Member of an oxysterol-binding protein family with seven members; in S. cerevisiae, family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; contains FFAT motif; interacts with ER anchor Scs2p at patches at the plasma membrane and at the nuclear envelope; regulated by sterol binding; OSH2 has a paralog, SWH1, that arose from the whole genome duplication [Source:SGD;Acc:S000002177]</Hit_def>
  <Hit_accession>YDL019C</Hit_accession>
  <Hit_len>1283</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>199.519</Hsp_bit-score>
      <Hsp_score>506</Hsp_score>
      <Hsp_evalue>8.37108e-52</Hsp_evalue>
      <Hsp_query-from>547</Hsp_query-from>
      <Hsp_query-to>1659</Hsp_query-to>
      <Hsp_hit-from>917</Hsp_hit-from>
      <Hsp_hit-to>1283</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>146</Hsp_identity>
      <Hsp_positive>199</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>382</Hsp_align-len>
      <Hsp_qseq>VNFNEPLSMLQRLTEDLEYFDLLDKAAKCESSLEQLCYVAAFXXXXXXXXXXRTGKPFNPLLGETFELDRLEECGYRSICEQVSXXXXXXXXXVDSRRGWRLWQEITVSSKFRGKYLSIIPLGTIHCEFPSSGNH----YTWKKVTTTVHNIIVGRLWIDQSGDIDIVNHHTGDKCQLKFIAYSYFSRDIPRKVSGVVMDAEGNAHYILSGTWDEKMEYAKIVQSSKGS------SGSEGRQKTVYQTQPAKHLWKRYPLPENSDNMYYFXXXXXXXXXXXXG-VAPTDSRLRPDQRLMENGKWDEANAEKQXXXXXXXXXXXXXXXXXXXXXXXGRKHQSYRPMWFERKEDPFTREVSCVYRGGYWETKEKQEWKISQDIF</Hsp_qseq>
      <Hsp_hseq>VTFNEPTSLLQRVAEDLEYSELLDQAATFEDSTLRTLYVAAFTASSYASTTKRVAKPFNPLLGETFEYSRPDK-QYRFFTEQVSHHPPISATWTESPR-WDFWGESFVDTKFNGRSFNVKHLGLWHIKLRPNDNEKEELYTWKKPNNTVIGILIGNPQVDNHGEVNVVNHTTGDHCKLYFKARGWRSSG-AYEITGEVYNKKKQKVWILGGHWNEAIFAKKVVKDGDLSLEKTRTAASAGNGPTDDGTKFL--IWKANDRPEEPFNLTPFAITLNAPQPHLLPWLPPTDTRLRPDQRAMEDGRYDEAGDEK----------FRVEEKQRAARRKREENNLEYHPQWFVRDTHPITKAKYWRYTGKYWVKRRDHDLKDCGDIF</Hsp_hseq>
      <Hsp_midline>V FNEP S+LQR+ EDLEY +LLD+AA  E S  +  YVAAF+ SSY++T  R  KPFNPLLGETFE  R ++  YR   EQVSHHPP +A   +S R W  W E  V +KF G+  ++  LG  H +   + N     YTWKK   TV  I++G   +D  G++++VNH TGD C+L F A  + S     +++G V + +    +IL G W+E +   K+V+    S      + S G   T   T+    +WK    PE   N+  F              + PTD+RLRPDQR ME+G++DEA  EK           R  E + A+  +    +  Y P WF R   P T+     Y G YW  +   + K   DIF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YAR042W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:192619:196185:1 gene:YAR042W transcript:YAR042W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWH1 description:Protein similar to mammalian oxysterol-binding protein; contains ankyrin repeats and FFAT motif; interacts with ER anchor Scs2p at the nucleus-vacuole junction; regulated by sterol binding; SWH1 has a paralog, OSH2, that arose from the whole genome duplication [Source:SGD;Acc:S000000081]</Hit_def>
  <Hit_accession>YAR042W</Hit_accession>
  <Hit_len>1188</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>198.749</Hsp_bit-score>
      <Hsp_score>504</Hsp_score>
      <Hsp_evalue>9.87171e-52</Hsp_evalue>
      <Hsp_query-from>547</Hsp_query-from>
      <Hsp_query-to>1659</Hsp_query-to>
      <Hsp_hit-from>819</Hsp_hit-from>
      <Hsp_hit-to>1188</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>147</Hsp_identity>
      <Hsp_positive>209</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>385</Hsp_align-len>
      <Hsp_qseq>VNFNEPLSMLQRLTEDLEYFDLLDKAAKCESSLEQLCYVAAFXXXXXXXXXXRTGKPFNPLLGETFELDRLEECGYRSICEQVSXXXXXXXXXVDSRRGWRLWQEITVSSKFRGKYLSIIPLGTIHCEFPSSGN------HYTWKKVTTTVHNIIVGRLWIDQSGDIDIVNHHTGDKCQLKFIAYSYFSRDIPRKVSGVVMDAEGNAHYILSGTWDEKMEYAKIVQSSKGSSGSEGRQKTVYQTQPAKHL-------WKRYPLPENSDNMYYFXXXXXXXXXXXXG-VAPTDSRLRPDQRLMENGKWDEANAEKQXXXXXXXXXXXXXXXXXXXXXXXGRKHQSYRPMWFERKEDPFTREVSCVYRGGYWETKEKQEWKISQDIF</Hsp_qseq>
      <Hsp_hseq>VSFNEPTSLLQRVSEDIEYSHILDQAATFEDSSLRMLYVAAFTASMYASTTNRVSKPFNPLLGETFEYART-DGQYRFFTEQVSHHPPISATWTESPK-WDFYGECNVDSSFNGRTFAVQHLGLWYITIRPDHNISVPEETYSWKKPNNTVIGILMGKPQVDNSGDVKVTNHTTGDYCMLHYKAHGWTSAG-AYEVRGEVFNKDDKKLWVLGGHWNDSI-YGKKV-TARGGELTLDRIKTANSATGGPKLDGSKFLIWKANERPSVPFNLTSFALTLNALPPHLIPYLAPTDSRLRPDQRAMENGEYDKAAAEKHRVEVKQRAAKKERE----------QKGEEYRPKWFVQEEHPVTKSLYWKFNGEYWNKRKNHDFKDCADIF</Hsp_hseq>
      <Hsp_midline>V+FNEP S+LQR++ED+EY  +LD+AA  E S  ++ YVAAF+ S Y++T  R  KPFNPLLGETFE  R  +  YR   EQVSHHPP +A   +S + W  + E  V S F G+  ++  LG  +       N       Y+WKK   TV  I++G+  +D SGD+ + NH TGD C L + A+ + S     +V G V + +    ++L G W++ + Y K V +++G   +  R KT         L       WK    P    N+  F      L       +APTDSRLRPDQR MENG++D+A AEK R+E KQR  ++ RE          +K + YRP WF ++E P T+ +   + G YW  ++  ++K   DIF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YHR073W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:242582:245572:1 gene:YHR073W transcript:YHR073W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:OSH3 description:Member of an oxysterol-binding protein family; this family has seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; contains FFAT motif; interacts with ER anchor Scs2p at patches at the plasma membrane; regulated by sterol binding [Source:SGD;Acc:S000001115]</Hit_def>
  <Hit_accession>YHR073W</Hit_accession>
  <Hit_len>996</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>107.071</Hsp_bit-score>
      <Hsp_score>266</Hsp_score>
      <Hsp_evalue>1.36596e-23</Hsp_evalue>
      <Hsp_query-from>547</Hsp_query-from>
      <Hsp_query-to>1434</Hsp_query-to>
      <Hsp_hit-from>662</Hsp_hit-from>
      <Hsp_hit-to>937</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>100</Hsp_identity>
      <Hsp_positive>147</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>304</Hsp_align-len>
      <Hsp_qseq>VNFNEPLSMLQRLTEDLEYFDLLDKAAKCESSLEQLCYVAAFXXXXXXXXXXRTG---KPFNPLLGETFELDRLEECGYRSICEQVSXXXXXXXXXVDSRRGWRLWQEITVSSKFRGKYLSIIPLGTIHCEFPSSGNHYTWKKVTTTVHNIIVGRLWIDQSGDIDIVNHHTGDKCQLKFIAYSYFS-RDIPRKVSGVVMDAEGNAHYILSGTWDEKMEYAKIVQSSKGSSGSEGRQKTVYQTQPAKHLWKRYPLPENSDNMYYFXXXXXXXXXXXX----GVAPTDSRLRPDQRLMENGKWDEA</Hsp_qseq>
      <Hsp_hseq>VTSNEPISILQLISETFEYAPLLTKATQRP---DPITFVSAFAISFLSIYRDKTRTLRKPFNPLLAETFELIR-EDMGFRLISEKVSHRPPVFAFFAE-HLDWECSYTVTPSQKFWGKSIELNNEGILRLKFKTTGELFEWTQPTTILKNLIAGERYMEPVNEFE-VHSSKGDKSHILFDKAGMFSGRSEGFKVSIIPPPSSNRKKETLAGKWTQSLA-----------------NETTHET-----IWEVGDLVSNPKKKYGFTKFTANLNEITEIEKGNLPPTDSRLRPDIRAYEEGNVDKA</Hsp_hseq>
      <Hsp_midline>V  NEP+S+LQ ++E  EY  LL KA +     + + +V+AF++S  S    +T    KPFNPLL ETFEL R E+ G+R I E+VSH PP  A   +    W     +T S KF GK + +   G +  +F ++G  + W + TT + N+I G  +++   + + V+   GDK  + F     FS R    KVS +   +       L+G W + +                   +T ++T     +W+   L  N    Y FT+    LNE  E     + PTDSRLRPD R  E G  D+A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YKR003W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:445381:446727:1 gene:YKR003W transcript:YKR003W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:OSH6 description:Member of an oxysterol-binding protein family; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; GFP-fusion protein localizes to the cell periphery; overexpression extends lifespan by promoting vacuolar fusion; OSH6 has a paralog, OSH7, that arose from the whole genome duplication [Source:SGD;Acc:S000001711]</Hit_def>
  <Hit_accession>YKR003W</Hit_accession>
  <Hit_len>448</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>2.466e-08</Hsp_evalue>
      <Hsp_query-from>568</Hsp_query-from>
      <Hsp_query-to>1221</Hsp_query-to>
      <Hsp_hit-from>78</Hsp_hit-from>
      <Hsp_hit-to>300</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>229</Hsp_align-len>
      <Hsp_qseq>SMLQRLTEDLEYFDLLDKAAKCESSLEQLCYVAAFXXXXXXXXXXRTGKPFNPLLGETF----ELDRLEECGYRSICEQVSXXXXX-XXXXVDSRRGWRLWQEITVSSKFRGKYLSIIPLGTIHCEF--PSSGN----HYTWKKVTTTVHNIIVGRLWIDQSGDIDIVNHHTGDKCQLKFIAYSYFSRDIPRKVSGVVMDAEGNAHYILSGTWDEKMEYAKIVQSSKGS</Hsp_qseq>
      <Hsp_hseq>SMLERVTNQLQFPEFLLQAHSEKDPLKRFLYVMKWYLAGWHIAPKAVKKPLNPVLGEYFTAYWDLPNKQQAYY--ISEQTSHHPPECAYFYMIPESSIRVDGVVIPKSRFLGNSSAAMMDGSTVLQFLDIKDGNGKPEKYVLTQPNVYVRGILFGKMRIELGDHMIIKSPNFQADIEFKTKGYVFGTYD---AIEGTVKDYDGNAYYEISGKWNDVM-YLKDLKQPRSS</Hsp_hseq>
      <Hsp_midline>SML+R+T  L++ + L +A   +  L++  YV  + ++ +        KP NP+LGE F    +L   ++  Y  I EQ SHHPP  A  ++      R+   +   S+F G   + +  G+   +F     GN     Y   +    V  I+ G++ I+    + I + +     + K   Y + + D    + G V D +GNA+Y +SG W++ M Y K ++  + S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YHR001W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:106055:107368:1 gene:YHR001W transcript:YHR001W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:OSH7 description:Oxysterol-binding protein; part of family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; OSH7 has a paralog, OSH6, that arose from the whole genome duplication [Source:SGD;Acc:S000001043]</Hit_def>
  <Hit_accession>YHR001W</Hit_accession>
  <Hit_len>437</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>1.91869e-06</Hsp_evalue>
      <Hsp_query-from>568</Hsp_query-from>
      <Hsp_query-to>1185</Hsp_query-to>
      <Hsp_hit-from>78</Hsp_hit-from>
      <Hsp_hit-to>289</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>220</Hsp_align-len>
      <Hsp_qseq>SMLQRLTEDLEYFDLLDKAAKCESSLEQLCYVAAFXXXXXXXXXXRTGKPFNPLLGETF----ELDRLEECGYRSICEQVSXX-XXXXXXXVDSRRGWRLWQEITVSSKFRGKYLSIIPLGTIHCEF----PSSGN--HYTWKKVTTTVHNIIVGRLWIDQSGDIDIVNHHTGDKCQLK---FIAYSYFSRDIPRKVSGVVMDAEGNAHYILSGTWDEKM</Hsp_qseq>
      <Hsp_hseq>SMLERITNQLQFPDVLLEAHSNKDGLQRFVKVVAWYLAGWHIGPRAVKKPLNPILGEHFTAYWDLPNKQQAFY--IAEQTSHHPPESAYFYMIPESNIRVDGVVVPKSKFLGNSSAAMMEGLTVLQFLDIKDANGKPEKYTLSQPNVYARGILFGKMRIELGDHMVIMGPKYQVDIEFKTKGFISGTYDA------IEGTIKDYDGKEYYQISGKWNDIM</Hsp_hseq>
      <Hsp_midline>SML+R+T  L++ D+L +A   +  L++   V A+ ++ +        KP NP+LGE F    +L   ++  Y  I EQ SHH P +A  ++      R+   +   SKF G   + +  G    +F     ++G    YT  +       I+ G++ I+    + I+        + K   FI+ +Y +      + G + D +G  +Y +SG W++ M</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>104</Statistics_hsp-len>
      <Statistics_eff-space>3900644917</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0009274-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.37|0.33|9|702|467</Iteration_query-def>
  <Iteration_query-len>2106</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1375689535</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0020411-RA transcript Note:&quot;Similar to PF13_0198 Reticulocyte-binding protein 2 homolog a (Plasmodium falciparum (isolate 3D7))&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.36|0.25|12|840|578</Iteration_query-def>
  <Iteration_query-len>2577</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1725390187</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052275-RA transcript Note:&quot;Similar to mtmr4 Myotubularin-related protein 4 (Xenopus laevis)&quot; offset:103 AED:0.19 eAED:0.19 QI:103|0.71|0.8|1|0.57|0.66|15|2562|589</Iteration_query-def>
  <Iteration_query-len>4435</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YJR110W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:633615:635681:1 gene:YJR110W transcript:YJR110W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YMR1 description:Phosphatidylinositol 3-phosphate (PI3P) phosphatase; involved in various protein sorting pathways, including CVT targeting and endosome to vacuole transport; has similarity to the conserved myotubularin dual specificity phosphatase family [Source:SGD;Acc:S000003871]</Hit_def>
  <Hit_accession>YJR110W</Hit_accession>
  <Hit_len>688</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>1.17764e-11</Hsp_evalue>
      <Hsp_query-from>602</Hsp_query-from>
      <Hsp_query-to>826</Hsp_query-to>
      <Hsp_hit-from>164</Hsp_hit-from>
      <Hsp_hit-to>241</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>43</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>78</Hsp_align-len>
      <Hsp_qseq>EVERMGYDLENA---WRTSEVNASYRLCASYPQQLLVPAWITDKELERVASFRSGKRIPVVVYRHQHNGAVIARSSQP</Hsp_qseq>
      <Hsp_hseq>EFRRQGLDSKDETCPWRLSTVNEHYEFCPTYPSKLFVPRSTSDILLKHASKFRSQKRIPVLTYHHKATDCNILRSSQP</Hsp_hseq>
      <Hsp_midline>E  R G D ++    WR S VN  Y  C +YP +L VP   +D  L+  + FRS KRIPV+ Y H+     I RSSQP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>102</Statistics_hsp-len>
      <Statistics_eff-space>3083432992</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052276-RA transcript Note:&quot;Similar to ROGDI Protein rogdi homolog (Bos taurus)&quot; offset:1966 AED:0.04 eAED:0.04 QI:1966|0.9|0.90|1|0.2|0.27|11|1185|133</Iteration_query-def>
  <Iteration_query-len>3553</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2434006761</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052277-RA transcript Note:&quot;Similar to SUSD2 Sushi domain-containing protein 2 (Homo sapiens)&quot; offset:0 AED:0.33 eAED:0.33 QI:0|0.55|0.52|0.63|0.83|0.73|19|1191|1152</Iteration_query-def>
  <Iteration_query-len>4650</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YPL270W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:30482:32803:1 gene:YPL270W transcript:YPL270W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MDL2 description:Mitochondrial inner membrane half-type ABC transporter; required for respiratory growth at high temperature; localizes to vacuole membrane in response to H2O2; similar to human TAP1 and TAP2 implicated in bare lymphocyte syndrome and Wegener-like granulomatosis [Source:SGD;Acc:S000006191]</Hit_def>
  <Hit_accession>YPL270W</Hit_accession>
  <Hit_len>773</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>147.902</Hsp_bit-score>
      <Hsp_score>372</Hsp_score>
      <Hsp_evalue>1.31223e-36</Hsp_evalue>
      <Hsp_query-from>52</Hsp_query-from>
      <Hsp_query-to>1188</Hsp_query-to>
      <Hsp_hit-from>213</Hsp_hit-from>
      <Hsp_hit-to>607</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>114</Hsp_identity>
      <Hsp_positive>185</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>396</Hsp_align-len>
      <Hsp_qseq>HQEVAFFDTTRTGDITSRLNXXXXXXXXXXXQNANVFLRSLVKAGGVCIFMFXXXXXXXXXXXXXXXXXXXXS-KFYGDFYEKLSKAVQDSLAVASGAAEETLAAIRTVRSLAGEEAECRRYRDALQHTYRHNRRQALAYAGFSCSNSLTQLALQVGILYYGGHLVVTDRISGAHLISFILYQMELGACLENMGSVYTGLMQAVGAAGKVFEYMEREPRMRTDGTLAPVQLEGQVSFKDVTFAYPSRPDAPVLKGVSFELQPGLVTALVGPSGSGKSSCVHLLQRLYEPLGGRVLLDGQSVHKYQHHYL-------HTKQALYNGELR-----GRTVLVIAHRLSSVERA----DHIVVLEHGRLVEQGPHAQLMQQGGLYARLVHRQMLGLPSAI</Hsp_qseq>
      <Hsp_hseq>HQDAEFFDNHKVGDLISRLGSDAYVVSRSMTQKVSDGVKALI-CGVVGVGMMCSLSPQLSILLLFFTPPVLFSASVFGKQIRNTSKDLQEATGQLTRVAEEQLSGIKTVQSFVAEGNELSRYNVAIRDIFQVGKTAAFTNAKFFTTTSLLGDLSFLTVLAYGSYLVLQSQLSIGDLTAFMLYTEYTGNAVFGLSTFYSEIMQGAGAASRLFELTDRKPSISPTVGHKYKPDRGVIEFKDVSFSYPTRPSVQIFKNLNFKIAPGSSVCIVGPSGRGKSTIALLLLRYYNPTTGTITIDNQDISKLNCKSLRRHIGIVQQEPVLMSGTIRDNITYGLTYTPTKEEIRSVAKQCFCHNFITKFPNTYDTVIGPHGTLLSGGQKQRIAIARALIKKPTIL</Hsp_hseq>
      <Hsp_midline>HQ+  FFD  + GD+ SRL SD  VVS  ++Q  +  +++L+  G V + M         + LL      L S   +G      SK +Q++    +  AEE L+ I+TV+S   E  E  RY  A++  ++  +  A   A F  + SL      + +L YG +LV+  ++S   L +F+LY    G  +  + + Y+ +MQ  GAA ++FE  +R+P +            G + FKDV+F+YP+RP   + K ++F++ PG    +VGPSG GKS+   LL R Y P  G + +D Q + K     L         +  L +G +R     G T       + SV +     + I    +      GPH  L+  G      + R ++  P+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YLR188W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:528300:530387:1 gene:YLR188W transcript:YLR188W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MDL1 description:Mitochondrial inner membrane half-type ABC transporter; mediates export of peptides generated upon proteolysis of mitochondrial proteins; plays a role in the regulation of cellular resistance to oxidative stress [Source:SGD;Acc:S000004178]</Hit_def>
  <Hit_accession>YLR188W</Hit_accession>
  <Hit_len>695</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>141.739</Hsp_bit-score>
      <Hsp_score>356</Hsp_score>
      <Hsp_evalue>6.87753e-35</Hsp_evalue>
      <Hsp_query-from>55</Hsp_query-from>
      <Hsp_query-to>1008</Hsp_query-to>
      <Hsp_hit-from>199</Hsp_hit-from>
      <Hsp_hit-to>524</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>99</Hsp_identity>
      <Hsp_positive>172</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>326</Hsp_align-len>
      <Hsp_qseq>QEVAFFDTTRTGDITSRLNXXXXXXXXXXXQNANVFLRSLVKAGGVCIFMFXXXXXXXXXXXXXXXXXXXXSKFYGDFYEKLSKAVQDSLAVASGAAEETLAAIRTVRSLAGEEAECRRYRDALQHTYRHNRRQALAYAGFSCSNSLTQLALQVGILYYGGHLVVTDRISGAHLISFILYQMELGACLENMGSVYTGLMQAVGAAGKVFEYMEREPRMRTDGTLAPVQL-EGQVSFKDVTFAYPSRPDAPVLKGVSFELQPGLVTALVGPSGSGKSSCVHLLQRLYEPLGGRVLLDGQSVHKYQHH-------YLHTKQALYNGEL</Hsp_qseq>
      <Hsp_hseq>QDATFLDTNRVGDLISRLSSDASIVAKSVTQNVSDGTRAIIQGFVGFGMMSFLSWKLTCVMMILAPPLGAMALIYGRKIRNLSRQLQTSVGGLTKVAEEQLNATRTIQAYGGEKNEVRRYAKEVRNVFHIGLKEAVTSGLFFGSTGLVGNTAMLSLLLVGTSMIQSGSMTVGELSSFMMYAVYTGSSLFGLSSFYSELMKGAGAAARVFELNDRKPLIRPTIGKDPVSLAQKPIVFKNVSFTYPTRPKHQIFKDLNITIKPGEHVCAVGPSGSGKSTIASLLLRYYDVNSGSIEFGDEDIRNFNLRKYRRLIGYVQQEPLLFNGTI</Hsp_hseq>
      <Hsp_midline>Q+  F DT R GD+ SRL+SD ++V+  V+QN +   R++++       M  LSW+L+ + ++  P +  ++  YG     LS+ +Q S+   +  AEE L A RT+++  GE+ E RRY   +++ +    ++A+    F  S  L      + +L  G  ++ +  ++   L SF++Y +  G+ L  + S Y+ LM+  GAA +VFE  +R+P +R      PV L +  + FK+V+F YP+RP   + K ++  ++PG     VGPSGSGKS+   LL R Y+   G +    + +  +          Y+  +  L+NG +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YMR301C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:867555:869627:-1 gene:YMR301C transcript:YMR301C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATM1 description:Mitochondrial inner membrane ATP-binding cassette (ABC) transporter; exports mitochondrially synthesized precursors of iron-sulfur (Fe/S) clusters to the cytosol; human homolog ABCB7 can complement yeast null mutant [Source:SGD;Acc:S000004916]</Hit_def>
  <Hit_accession>YMR301C</Hit_accession>
  <Hit_len>690</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.8929</Hsp_bit-score>
      <Hsp_score>224</Hsp_score>
      <Hsp_evalue>6.95813e-19</Hsp_evalue>
      <Hsp_query-from>331</Hsp_query-from>
      <Hsp_query-to>960</Hsp_query-to>
      <Hsp_hit-from>294</Hsp_hit-from>
      <Hsp_hit-to>503</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>221</Hsp_align-len>
      <Hsp_qseq>ASGAAEETLAAIRTVRSLAGEEAECRRYRDALQHTYRHNR---RQALAYAGFSCSNSLTQLALQVGILYYG------GHLVVTDRISGAHLISFILYQMELGACLENMGSVYTGLMQAVGAAGKVFEYMEREPRMRT--DGTLAPVQLEGQVSFKDVTFAYPSRPDAPVLKGVSFELQPGLVTALVGPSGSGKSSCVHLLQRLYEPLGGRVLLDGQSVHKY</Hsp_qseq>
      <Hsp_hseq>AASVALDSLINFEAVKYFNNEKYLADKYNGSLMN-YRDSQIKVSQSLAFLN-SGQNLIFTTAL-TAMMYMGCTGVIGGNLTVGDLV----LINQLVFQ--LSVPLNFLGSVYRDLKQSLIDMETLFKLRKNEVKIKNAERPLMLPENVPYDITFENVTFGY--HPDRKILKNASFTIPAGWKTAIVGSSGSGKSTILKLVFRFYDPESGRILINGRDIKEY</Hsp_hseq>
      <Hsp_midline>A+  A ++L     V+    E+    +Y  +L + YR ++    Q+LA+   S  N +   AL   ++Y G      G+L V D +    LI+ +++Q  L   L  +GSVY  L Q++     +F+  + E +++      + P  +   ++F++VTF Y   PD  +LK  SF +  G  TA+VG SGSGKS+ + L+ R Y+P  GR+L++G+ + +Y</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>9.74656e-06</Hsp_evalue>
      <Hsp_query-from>976</Hsp_query-from>
      <Hsp_query-to>1152</Hsp_query-to>
      <Hsp_hit-from>606</Hsp_hit-from>
      <Hsp_hit-to>670</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>39</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>65</Hsp_align-len>
      <Hsp_qseq>HTKQALY-----NGELRGRTVLVIAHRLSSVERADHIVVLEHGRLVEQGPHAQLMQQ-GGLYARL</Hsp_qseq>
      <Hsp_hseq>HTEQALLRTIRDNFTSGSRTSVYIAHRLRTIADADKIIVLDNGRVREEGKHLELLAMPGSLYREL</Hsp_hseq>
      <Hsp_midline>HT+QAL      N     RT + IAHRL ++  AD I+VL++GR+ E+G H +L+   G LY  L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YKL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:42423:46295:-1 gene:YKL209C transcript:YKL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE6 description:Plasma membrane ATP-binding cassette (ABC) transporter; required for the export of a-factor, catalyzes ATP hydrolysis coupled to a-factor transport; contains 12 transmembrane domains and two ATP binding domains; expressed only in MATa cells; human homolog ABCB1 mediates multidrug resistance in many chemotherapy-resistant tumors by effluxing toxic compounds from the cell [Source:SGD;Acc:S000001692]</Hit_def>
  <Hit_accession>YKL209C</Hit_accession>
  <Hit_len>1290</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.7886</Hsp_bit-score>
      <Hsp_score>177</Hsp_score>
      <Hsp_evalue>3.66797e-13</Hsp_evalue>
      <Hsp_query-from>268</Hsp_query-from>
      <Hsp_query-to>1065</Hsp_query-to>
      <Hsp_hit-from>879</Hsp_hit-from>
      <Hsp_hit-to>1163</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>122</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>286</Hsp_align-len>
      <Hsp_qseq>SKFYGDFYEKLSKAVQDSLAVASGAAEETLAAIRTVRSLAGEEAECRRYRDALQHTYRHNRRQALAYAGFSCS-NSLTQLALQVGILYYGGHLVVTDRISGAHLISFILYQMELGACLENMGSVYTGLMQAVGAAGKVFEYM-EREPRMRTDGTLA-PVQLEGQ----------VSFKDVTFAYPSRPDAPVLKGVSFELQPGLVTALVGPSGSGKSSCVHLLQRLYEPLGGRVLLDGQSVHKYQHHYLHT-------KQALYNGELRGRTVLVIAHRLSSVERAD</Hsp_qseq>
      <Hsp_hseq>SAIYGGILQKCETDYKTSVAQLENCLYQIVTNIKTIKCLQAEFHFQLTYHDLKIKMQQIASKRAIA-TGFGISMTNMIVMCIQAIIYYYGLKLVMIHEYTSKEMFTTFTLLLFTIMSCTSLVSQIPDISRGQRAASWIYRILDEKHNTLEVENNNARTVGIAGHTYHGKEKKPIVSIQNLTFAYPSAPTAFVYKNMNFDMFCGQTLGIIGESGTGKSTLVLLLTKLYNCEVGKIKIDGTDVNDWNLTSLRKEISVVEQKPLLFNGTIRDNLTYGLQDEILEIEMYD</Hsp_hseq>
      <Hsp_midline>S  YG   +K     + S+A       + +  I+T++ L  E      Y D      +   ++A+A  GF  S  ++  + +Q  I YYG  LV+    +   + +     +       ++ S    + +   AA  ++  + E+   +  +   A  V + G           VS +++TFAYPS P A V K ++F++  G    ++G SG+GKS+ V LL +LY    G++ +DG  V+ +    L         K  L+NG +R      +   +  +E  D</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>70.8626</Hsp_bit-score>
      <Hsp_score>172</Hsp_score>
      <Hsp_evalue>1.39398e-12</Hsp_evalue>
      <Hsp_query-from>352</Hsp_query-from>
      <Hsp_query-to>1026</Hsp_query-to>
      <Hsp_hit-from>219</Hsp_hit-from>
      <Hsp_hit-to>455</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>237</Hsp_align-len>
      <Hsp_qseq>TLAAIRTVRSLAGEEAECRRYRDALQHTYRHNRRQALAYAGFSCSNSLTQLALQVGILYYGGHLVVTDRISGAHLISFILYQMELGACLENMGSVYTGLMQAVGAAGKVFEYME----REPRMRTDGTLAPVQL-EGQVSFKDVTFAYPSRPDAPVLKGVSFELQPGLVTALVGPSGSGKSSCVHLLQRLYEPLGGRVLLDGQSVHKYQHHYL-------HTKQALYNGELRGRTVL</Hsp_qseq>
      <Hsp_hseq>SMNAAQLVRLYCTQRLERKKFKEIILNCNTFFIKSCFFVAANAGILRFLTLTMFVQGFWFGSAMIKKGKLNINDVITCFHSCIMLGSTLNNTLHQIVVLQKGGVAMEKIMTLLKDGSKRNPLNKTVAHQFPLDYATSDLTFANVSFSYPSRPSEAVLKNVSLNFSAGQFTFIVGKSGSGKSTLSNLLLRFYDGYNGSISINGHNIQTIDQKLLIENITVVEQRCTLFNDTLRKNILL</Hsp_hseq>
      <Hsp_midline>++ A + VR    +  E +++++ + +      +     A  +       L + V   ++G  ++   +++   +I+     + LG+ L N       L +   A  K+   ++    R P  +T     P+      ++F +V+F+YPSRP   VLK VS     G  T +VG SGSGKS+  +LL R Y+   G + ++G ++       L         +  L+N  LR   +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YHL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:27978:32756:-1 gene:YHL035C transcript:YHL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VMR1 description:Vacuolar membrane protein; involved in multiple drug resistance and metal sensitivity; ATP-binding cassette (ABC) family member involved in drug transport; potential Cdc28p substrate; induced under respiratory conditions; VMR1 has a paralog, YBT1, that arose from the whole genome duplication [Source:SGD;Acc:S000001027]</Hit_def>
  <Hit_accession>YHL035C</Hit_accession>
  <Hit_len>1592</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>1.48272e-07</Hsp_evalue>
      <Hsp_query-from>742</Hsp_query-from>
      <Hsp_query-to>957</Hsp_query-to>
      <Hsp_hit-from>1320</Hsp_hit-from>
      <Hsp_hit-to>1390</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>26</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>73</Hsp_align-len>
      <Hsp_qseq>EGQVSFKDVTFAY-PSRPDAPVLKGVSFELQPGLVTALVGPSGSGKSSCVHLLQRLYEPLGGRVLLDGQSVHK</Hsp_qseq>
      <Hsp_hseq>DGEIEIENLSLRYAPNLP--PVIRNVSFKVDPQSKIGIVGRTGAGKSTIITALFRLLEPITGCIKIDGQDISK</Hsp_hseq>
      <Hsp_midline>+G++  ++++  Y P+ P  PV++ VSF++ P     +VG +G+GKS+ +  L RL EP+ G + +DGQ + K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YGR281W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:1052824:1057257:1 gene:YGR281W transcript:YGR281W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YOR1 description:Plasma membrane ATP-binding cassette (ABC) transporter; multidrug transporter mediates export of many different organic anions including oligomycin; homolog of human cystic fibrosis transmembrane receptor (CFTR) [Source:SGD;Acc:S000003513]</Hit_def>
  <Hit_accession>YGR281W</Hit_accession>
  <Hit_len>1477</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>1.74818e-06</Hsp_evalue>
      <Hsp_query-from>559</Hsp_query-from>
      <Hsp_query-to>993</Hsp_query-to>
      <Hsp_hit-from>1144</Hsp_hit-from>
      <Hsp_hit-to>1292</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>154</Hsp_align-len>
      <Hsp_qseq>ISGAHLISFILYQMELGACLENMGSVYTGLMQAVGAAGKVFEYME--------REPRMRTDGTLAPVQLEGQVSFKDVTFAYPSRPDAP-VLKGVSFELQPGLVTALVGPSGSGKSSCVHLLQRLYEPLGGRVLLDGQSVHKYQHHYLHTKQAL</Hsp_qseq>
      <Hsp_hseq>ISAASVGVLLTYVLQLPGLLNTILRAMTQTENDMNSAERLVTYATELPLEASYRKPEMTPPESWPSM---GEIIFENVDFAY--RPGLPIVLKNLNLNIKSGEKIGICGRTGAGKSTIMSALYRLNELTAGKILIDNVDISQLGLFDLRRKLAI</Hsp_hseq>
      <Hsp_midline>IS A +   + Y ++L   L  +    T     + +A ++  Y          R+P M    +   +   G++ F++V FAY  RP  P VLK ++  ++ G    + G +G+GKS+ +  L RL E   G++L+D   + +     L  K A+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3232984349</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052278-RA transcript Note:&quot;Similar to slc15a4 Solute carrier family 15 member 4 (Xenopus laevis)&quot; offset:0 AED:0.35 eAED:0.35 QI:0|0|0.5|1|0|0|2|642|232</Iteration_query-def>
  <Iteration_query-len>1341</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>93</Statistics_hsp-len>
      <Statistics_eff-space>814294518</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0007432-RA transcript Note:&quot;Similar to ERCC6L DNA excision repair protein ERCC-6-like (Homo sapiens)&quot; offset:148 AED:0.40 eAED:0.40 QI:148|0.95|0.90|1|0|0.04|22|0|865</Iteration_query-def>
  <Iteration_query-len>2746</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YJR035W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:497355:500612:1 gene:YJR035W transcript:YJR035W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD26 description:Protein involved in transcription-coupled nucleotide excision repair; repairs UV-induced DNA lesions; recruitment to DNA lesions is dependent on an elongating RNA polymerase II; homolog of human CSB protein [Source:SGD;Acc:S000003796]</Hit_def>
  <Hit_accession>YJR035W</Hit_accession>
  <Hit_len>1085</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>263.848</Hsp_bit-score>
      <Hsp_score>673</Hsp_score>
      <Hsp_evalue>1.35165e-74</Hsp_evalue>
      <Hsp_query-from>440</Hsp_query-from>
      <Hsp_query-to>2104</Hsp_query-to>
      <Hsp_hit-from>283</Hsp_hit-from>
      <Hsp_hit-to>823</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>208</Hsp_identity>
      <Hsp_positive>310</Hsp_positive>
      <Hsp_gaps>108</Hsp_gaps>
      <Hsp_align-len>602</Hsp_align-len>
      <Hsp_qseq>LGSGFNLYHELHNQLYSHQLEGVAWLYNLFKNKRKGGILADDMGLGKTIQVISFLSGMFDASLF-GHVLLVMPTTLMSIWISEFDKWAP------------GITIREFYGTKSERTRNL--------------QKVQRTQGVVITSYQL------LVNNWHEL-STYQG---H-----EFIWDAMILDEGXXXXXXXXXXXXXXXXXPAHFRMILTGTPVQNNLKEIWALFDFVCEGSLLGTSKTFKMEYENPITKARQKDATVGEKALGTRMAENLQELIGPYFLRRTKAEVQSKELHAKQLRDNKENDPTVGNLDQRIQIEMPTLTRKNDLIVWVYLSPVQEQIYRDFQNLDDIKELLDSTRSPLVALGILKKICVHPRLLPERACAQLGLNQQFGRIESEGLQSNWFLSSIKNVPPKTLIEESGKLTFLIGLLERLRQEGHRTLVFSQSLKMLDIIDHILKHQG-----FKVMRIDGTITHITEREKRVQTFQKDSAFNXXXXXXXXXXXXXXXXAANRVVILDPSWNPATDAQAVDRAYRIGQTDNVIIYRLVTCGTMEEKIYRRQIFKESLIRQTTGDKKNPFRYFSQQELRELFIL</Hsp_qseq>
      <Hsp_hseq>LNSQFKIPGEIYSLLFNYQKTCVQWLYELYQ-QNCGGIIGDEMGLGKTIQVIAFIAALHHSGLLTGPVLIVCPATVMKQWCNEFQHWWPPLRTVILHSMGSGMASDQKFKMDENDLENLIMNSKPSDFSYEDWKNSTRTKKALESSYHLDKLIDKVVTDGHILITTYVGLRIHSDKLLKVKWQYAVLDEGHKIRNPDSEISLTCKKLKTHNRIILSGTPIQNNLTELWSLFDFIFPGKL-GTLPVFQQQFVIPINIGGYANATNIQVQTGYKCAVALRDLISPYLLRRVKADV------AKDLPQKKE------------------------MVLFCKLTKYQRSKYLEFLHSSDLNQIQNGKRNVLFGIDILRKICNHPDLLDRDTKRH---NPDYG-------------------DPK----RSGKMQVVKQLLLLWHKQGYKALLFTQSRQMLDILEEFISTKDPDLSHLNYLRMDGT-TNIKGRQSLVDRFNNES-FDVFLLTTRVGGLGVNLTGANRIIIFDPDWNPSTDMQARERAWRIGQKREVSIYRLMVGGSIEEKIYHRQIFKQFLTNRILTDPKQK-RFFKIHELHDLFSL</Hsp_hseq>
      <Hsp_midline>L S F +  E+++ L+++Q   V WLY L++ +  GGI+ D+MGLGKTIQVI+F++ +  + L  G VL+V P T+M  W +EF  W P            G+   + +        NL              +   RT+  + +SY L      +V + H L +TY G   H     +  W   +LDEGHKI+   ++ + +   +  H R+IL+GTP+QNNL E+W+LFDF+  G L GT   F+ ++  PI      +AT  +   G + A  L++LI PY LRR KA+V      AK L   KE                        ++++  L+  Q   Y +F +  D+ ++ +  R+ L  + IL+KIC HP LL          N  +G                    PK     SGK+  +  LL    ++G++ L+F+QS +MLDI++  +  +         +R+DGT T+I  R+  V  F  +S F+VFLLTT+VGG+G+ LT ANR++I DP WNP+TD QA +RA+RIGQ   V IYRL+  G++EEKIY RQIFK+ L  +   D K   R+F   EL +LF L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YPL082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:398480:404083:-1 gene:YPL082C transcript:YPL082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MOT1 description:Essential protein involved in regulation of transcription; removes Spt15p (TBP) from DNA via its C-terminal ATPase activity; may have a role in ensuring that soluble TBP is available to bind TATA-less promoters; forms a complex with TBP that binds TATA DNA with high affinity but with altered specificity; the Mot1p-Spt15p-DNA ternary complex contains unbent DNA; coregulates transcription with Spt16p through assembly of preinitiation complex and organization of nucleosomes [Source:SGD;Acc:S000006003]</Hit_def>
  <Hit_accession>YPL082C</Hit_accession>
  <Hit_len>1867</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>202.601</Hsp_bit-score>
      <Hsp_score>514</Hsp_score>
      <Hsp_evalue>8.47169e-54</Hsp_evalue>
      <Hsp_query-from>401</Hsp_query-from>
      <Hsp_query-to>2098</Hsp_query-to>
      <Hsp_hit-from>1240</Hsp_hit-from>
      <Hsp_hit-to>1800</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>190</Hsp_identity>
      <Hsp_positive>302</Hsp_positive>
      <Hsp_gaps>93</Hsp_gaps>
      <Hsp_align-len>610</Hsp_align-len>
      <Hsp_qseq>ISSDDEEDEYINVL-----GSGFNLYHELHNQLYSHQLEGVAWLYNLFKNKRK-GGILADDMGLGKTIQVISFLSGMFDASLFGH--------------VLLVMPTTLMSIWISEFDKWAPGITIREFYGTKSERTRNLQKVQRTQGVVITSYQLLVNNWHELSTYQGHEFIWDAMILDEGXXXXXXXXXXXXXXXXXPAHFRMILTGTPVQNNLKEIWALFDFVCEGSLLGTSKTFKMEYENPITKARQKDATVGEKALGTRMAENLQELIGPYFLRRTKAEVQSKELHAKQLRDNKENDPTVGNLDQRIQIEMPTLTRKNDLIVWVYLSPVQEQIYRDF----QNL--DDIK--ELLDSTRSPLVALGILKKICVHPRLLPERACAQLGLNQQFGRIESEGLQSNWFLSSIKNVPPKTLIEESGKLTFLIG---LLERLRQEG----------HRTLVFSQSLKMLDIIDHILKHQ---GFKVMRIDGTITHITEREKRVQTFQKDSAFNXXXXXXXXXXXXXXXXAANRVVILDPSWNPATDAQAVDRAYRIGQTDNVIIYRLVTCGTMEEKIYRRQIFKESLIRQTTGDKKNPFRYFSQQELRELF</Hsp_qseq>
      <Hsp_hseq>VASRERERDFIQQMMDPSKAKPFKLPIAIKATLRKYQQDGVNWLA--FLNKYHLHGILCDDMGLGKTLQTICIIAS--DQYLRKEDYEKTRSVESRALPSLIICPPSLTGHWENEFDQYAPFLKVVVYAGGPTVRL-TLRPQLSDADIIVTSYDVARNDLAVLNKTE-----YNYCVLDEGHIIKNSQSKLAKAVKEITANHRLILTGTPIQNNVLELWSLFDFLMPG-FLGTEKMFQERFAKPIAASRNSKTSSKEQEAGVLALEALHKQVLPFMLRRLKEDVLS-DLPPKIIQD-----------------------------YYCELGDLQKQLYMDFTKKQKNVVEKDIENSEIADGKQHIFQALQYMRKLCNHPALVLSPNHPQLAQVQDY--LKQTGLDLHDIINAPKLSALRTLLFECG-----IGEEDIDKKASQDQNFPIQNVISQHRALIFCQLKDMLDMVENDLFKKYMPSVTYMRLDGSIDP-RDRQKVVRKFNEDPSIDCLLLTTKVGGLGLNLTGADTVIFVEHDWNPMNDLQAMDRAHRIGQKKVVNVYRIITKGTLEEKIMGLQKFKMNIASTVVNQQNSGLASMDTHQLLDLF</Hsp_hseq>
      <Hsp_midline>++S + E ++I  +        F L   +   L  +Q +GV WL   F NK    GIL DDMGLGKT+Q I  ++   D  L                  L++ P +L   W +EFD++AP + +  + G  + R   L+       +++TSY +  N+   L+  +     ++  +LDEGH IK S +K AK+   I A+ R+ILTGTP+QNN+ E+W+LFDF+  G  LGT K F+  +  PI  +R    +  E+  G    E L + + P+ LRR K +V S +L  K ++D                              +  L  +Q+Q+Y DF    +N+   DI+  E+ D  +    AL  ++K+C HP L+      QL   Q +  ++  GL  +  +++ K    +TL+ E G     IG   + ++  Q+           HR L+F Q   MLD++++ L  +       MR+DG+I    +R+K V+ F +D + +  LLTT+VGG+GL LT A+ V+ ++  WNP  D QA+DRA+RIGQ   V +YR++T GT+EEKI   Q FK ++       + +        +L +LF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YOR304W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:884514:887876:1 gene:YOR304W transcript:YOR304W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ISW2 description:ATP-dependent DNA translocase involved in chromatin remodeling; ATPase component that, with Itc1p, forms a complex required for repression of a-specific genes, INO1, and early meiotic genes during mitotic growth; the Isw2 complex exhibits basal levels of chromatin binding throughout the genome as well as target-specific chromatin interactions; targeted by Ume6p- and Sua7p-dependent DNA looping to many loci genome-wide [Source:SGD;Acc:S000005831]</Hit_def>
  <Hit_accession>YOR304W</Hit_accession>
  <Hit_len>1120</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>199.519</Hsp_bit-score>
      <Hsp_score>506</Hsp_score>
      <Hsp_evalue>3.95485e-53</Hsp_evalue>
      <Hsp_query-from>479</Hsp_query-from>
      <Hsp_query-to>2050</Hsp_query-to>
      <Hsp_hit-from>183</Hsp_hit-from>
      <Hsp_hit-to>646</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>165</Hsp_identity>
      <Hsp_positive>259</Hsp_positive>
      <Hsp_gaps>98</Hsp_gaps>
      <Hsp_align-len>543</Hsp_align-len>
      <Hsp_qseq>QLYSHQLEGVAWLYNLFKNKRKGGILADDMGLGKTIQVISFLSGM-FDASLFGHVLLVMPTTLMSIWISEFDKWAPGITIREFYGTKSERT---RNLQKVQRTQGVVITSYQLLVNNWHELSTYQGHEFIWDAMILDEGXXXXXXXXXXXXXXXXXPAHFRMILTGTPVQNNLKEIWALFDFVCEGSLLGTSKTFKMEYENPITKARQKDATVGEKALGTRMAENLQELIGPYFLRRTKAEVQSKELHAKQLRDNKENDPTVGNLDQRIQIEMPTLTRKNDLIVWVYLSPVQEQIYRDFQNLDDIKELLDSTRSPLVALGI---LKKICVHPRLLPERACAQLGLNQQFGRIESEGLQSNWFLSSIKNVPPKT----LIEESGKLTFLIGLLERLRQEGHRTLVFSQSLKMLDIIDHILKHQGFKVMRIDGTITHITEREKRVQTFQKDSAFNXXXXXXXXXXXX----XXXXAANRVVILDPSWNPATDAQAVDRAYRIGQTDNVIIYRLVTCGTMEEKIYRRQIFKESL----IRQTTGDK</Hsp_qseq>
      <Hsp_hseq>KLRDYQVQGLNWLISLHENKL-SGILADEMGLGKTLQTISFLGYLRYVKQIEGPFLIIVPKSTLDNWRREFLKWTPNVNVLVLHGDKDTRADIVRNIILEARFD-VLITSYEMVIREKNALK-----RLAWQYIVIDEAHRIKNEQSALSQIIRLFYSKNRLLITGTPLQNNLHELWALLNFLL-PDIFGDSELFDEWFEQNNSEQDQE-----------IVIQQLHSVLNPFLLRRVKADVE------KSLLPKIETNVYVGMTDMQIQ--------------W-YKSLLEKDI-------DAVNGAVGKREGKTRLLNIVMQLRKCCNHPYLF-------------------EGAEPG---------PPYTTDEHLIFNSGKMIILDKLLKRLKEKGSRVLIFSQMSRLLDILEDYCYFRDFEYCRIDGSTSH----EERIEAIDEYNKPNSEKFVFLLTTRAGGLGINLVTADTVILFDSDWNPQADLQAMDRAHRIGQKKQVHVYRFVTENAIEEKVIERAAQKLRLDQLVIQQGTGKK</Hsp_hseq>
      <Hsp_midline>+L  +Q++G+ WL +L +NK   GILAD+MGLGKT+Q ISFL  + +   + G  L+++P + +  W  EF KW P + +   +G K  R    RN+    R   V+ITSY++++   + L         W  +++DE H+IK   +  ++      +  R+++TGTP+QNNL E+WAL +F+    + G S+ F   +E   ++  Q+            + + L  ++ P+ LRR KA+V+      K L    E +  VG  D +IQ              W Y S +++ I       D +   +         L I   L+K C HP L                    EG +           PP T    LI  SGK+  L  LL+RL+++G R L+FSQ  ++LDI++     + F+  RIDG+ +H    E+R++   + +  N       +        + L  A+ V++ D  WNP  D QA+DRA+RIGQ   V +YR VT   +EEK+  R   K  L    I+Q TG K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YOR290C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:855147:860258:-1 gene:YOR290C transcript:YOR290C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF2 description:Catalytic subunit of the SWI/SNF chromatin remodeling complex; involved in transcriptional regulation; contains DNA-stimulated ATPase activity; functions interdependently in transcriptional activation with Snf5p and Snf6p [Source:SGD;Acc:S000005816]</Hit_def>
  <Hit_accession>YOR290C</Hit_accession>
  <Hit_len>1703</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>198.364</Hsp_bit-score>
      <Hsp_score>503</Hsp_score>
      <Hsp_evalue>1.72811e-52</Hsp_evalue>
      <Hsp_query-from>482</Hsp_query-from>
      <Hsp_query-to>2005</Hsp_query-to>
      <Hsp_hit-from>767</Hsp_hit-from>
      <Hsp_hit-to>1224</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>165</Hsp_identity>
      <Hsp_positive>264</Hsp_positive>
      <Hsp_gaps>76</Hsp_gaps>
      <Hsp_align-len>521</Hsp_align-len>
      <Hsp_qseq>LYSHQLEGVAWLYNLFKNKRKGGILADDMGLGKTIQVISFLSGMFD-ASLFGHVLLVMPTTLMSIWISEFDKWAPGITIREFYGTKSERTRNLQKVQRTQ-GVVITSYQLLVNNWHELSTYQGHEFIWDAMILDEGXXXXXXXXXXXXXXXXX-PAHFRMILTGTPVQNNLKEIWALFDFVCEGSLLGTSKTFKMEYENPITKARQKDATVGEKALGTRMAENLQELIGPYFLRRTKAEVQSKELHAKQLRDNKENDPTVGNLDQRIQIEMPTLTRKNDLIVWVYLSPVQEQIYRDFQNLDDIKELL--DSTRSPLVAL-GI------LKKICVHPRLLPERACAQLGLNQQFGRIESEGLQSNWFLSSIKNVPPKTLIEESGKLTFLIGLLERLRQEGHRTLVFSQSLKMLDIIDHILKHQGFKVMRIDGTITHITEREKRVQTFQ-KDSAFNXXXXXXXXXXXXXXXXAANRVVILDPSWNPATDAQAVDRAYRIGQTDNVIIYRLVTCGTMEEKIYRR</Hsp_qseq>
      <Hsp_hseq>LKDYQIKGLQWMVSLFNN-HLNGILADEMGLGKTIQTISLLTYLYEMKNIRGPYLVIVPLSTLSNWSSEFAKWAPTLRTISFKGSPNERKAKQAKIRAGEFDVVLTTFEYIIKERALLSKVK-----WVHMIIDEGHRMKNAQSKLSLTLNTHYHADYRLILTGTPLQNNLPELWALLNFVLP-KIFNSVKSFDEWFNTPFANTGGQDKIELSEEETLLVIRRLHKVLRPFLLRRLKKDVEK---------------------------ELPDKVEK---VVKCKMSALQQIMY---QQMLKYRRLFIGDQNNKKMVGLRGFNNQIMQLKKICNHPFV--------------FEEVEDQINPTRETNDDIWRV--------AGKFELLDRILPKLKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGH-TKSDERSELLRLFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTNSVEEVILER</Hsp_hseq>
      <Hsp_midline>L  +Q++G+ W+ +LF N    GILAD+MGLGKTIQ IS L+ +++  ++ G  L+++P + +S W SEF KWAP +    F G+ +ER     K++  +  VV+T+++ ++     LS  +     W  MI+DEGH++K + +K + + +    A +R+ILTGTP+QNNL E+WAL +FV    +  + K+F   +  P      +D     +     +   L +++ P+ LRR K +V+                            E+P    K   +V   +S +Q+ +Y   Q +   + L   D     +V L G       LKKIC HP +              F  +E +   +      I  V        +GK   L  +L +L+  GHR L+F Q  +++DI++  L++   K +R+DG  T   ER + ++ F   DS +  F+L+T+ GG+GL L  A+ V+I D  WNP  D QA DRA+RIGQ + V I RL+T  ++EE I  R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YGL163C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:193707:196403:-1 gene:YGL163C transcript:YGL163C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD54 description:DNA-dependent ATPase that stimulates strand exchange; modifies the topology of double-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; member of the SWI/SNF family of DNA translocases; forms nuclear foci upon DNA replication stress [Source:SGD;Acc:S000003131]</Hit_def>
  <Hit_accession>YGL163C</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>189.504</Hsp_bit-score>
      <Hsp_score>480</Hsp_score>
      <Hsp_evalue>3.35567e-50</Hsp_evalue>
      <Hsp_query-from>545</Hsp_query-from>
      <Hsp_query-to>2098</Hsp_query-to>
      <Hsp_hit-from>330</Hsp_hit-from>
      <Hsp_hit-to>824</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>163</Hsp_identity>
      <Hsp_positive>258</Hsp_positive>
      <Hsp_gaps>71</Hsp_gaps>
      <Hsp_align-len>542</Hsp_align-len>
      <Hsp_qseq>GGILADDMGLGKTIQVISFL-----SGMFDASLFGHVLLVMPTTLMSIWISEFDKWAPGITIREFY---------GTKSERTRNLQKVQRTQG------VVITSYQLLVNNWHELSTYQGHEFIWDAMILDEGXXXXXXXXXXXXXXXXXPAHFRMILTGTPVQNNLKEIWALFDFVCEGSLLGTSKTFKMEYENPITKARQKDATVGEKALGTRMAENLQELIGPYFLRRTKAEVQSKELHAKQLRDNKENDPTVGNLDQRIQIEMPTLTRKNDLIVWVYLSPVQEQIYRDFQNLDDIKELLDSTRS--PLVALGILKKICVHPRLLPERACAQLGLNQQFGRIESEGLQSNWFLSSIKNVPPKTLIEESGKLTFLIGLLERLRQEGHRTLVF-SQSLKMLDIIDHILKHQGFKVMRIDGTITHITEREKRVQTFQKDSAFNXX-XXXXXXXXXXXXXXAANRVVILDPSWNPATDAQAVDRAYRIGQTDNVIIYRLVTCGTMEEKIYRRQIFKESLIRQTTGDKKNPFRYFSQQELRELF</Hsp_qseq>
      <Hsp_hseq>GCIMADEMGLGKTLQCIALMWTLLRQGPQGKRLIDKCIIVCPSSLVNNWANELIKWLGPNTLTPLAVDGKKSSMGGGNTTVSQAIHAWAQAQGRNIVKPVLIISYETLRRNVDQLKNCN-----VGLMLADEGHRLKNGDSLTFTALDSISCPRRVILSGTPIQNDLSEYFALLSFSNPG-LLGSRAEFRKNFENPILRGRDADATDKEITKGEAQLQKLSTIVSKFIIRRT-------------------ND-----------ILAKYLPCKYEHVIFVNLKPLQNELYNKLIKSREVKKVVKGVGGSQPLRAIGILKKLCNHPNLL------NFEDEFDDEDDLELPDDYNMPGSKARDVQTKY----SAKFSILERFLHKIKTESDDKIVLISNYTQTLDLIEKMCRYKHYSAVRLDGTMS-INKRQKLVDRFNDPEGQEFIFLLSSKAGGCGINLIGANRLILMDPDWNPAADQQALARVWRDGQKKDCFIYRFISTGTIEEKIFQRQSMKMSLSSCVVDAKEDVERLFSSDNLRQLF</Hsp_hseq>
      <Hsp_midline>G I+AD+MGLGKT+Q I+ +      G     L    ++V P++L++ W +E  KW    T+             G  +  ++ +    + QG      V+I SY+ L  N  +L            M+ DEGH++K   + T  +  +I    R+IL+GTP+QN+L E +AL  F   G LLG+   F+  +ENPI + R  DAT  E   G    + L  ++  + +RRT                   ND           I    L  K + +++V L P+Q ++Y       ++K+++       PL A+GILKK+C HP LL                        N   S  ++V  K     S K + L   L +++ E    +V  S   + LD+I+ + +++ +  +R+DGT++ I +R+K V  F          LL+++ GG G+ L  ANR++++DP WNPA D QA+ R +R GQ  +  IYR ++ GT+EEKI++RQ  K SL       K++  R FS   LR+LF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YIL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:117992:122071:1 gene:YIL126W transcript:YIL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STH1 description:ATPase component of the RSC chromatin remodeling complex; required for expression of early meiotic genes; promotes base excision repair in chromatin; essential helicase-related protein homologous to Snf2p [Source:SGD;Acc:S000001388]</Hit_def>
  <Hit_accession>YIL126W</Hit_accession>
  <Hit_len>1359</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>191.045</Hsp_bit-score>
      <Hsp_score>484</Hsp_score>
      <Hsp_evalue>3.38831e-50</Hsp_evalue>
      <Hsp_query-from>482</Hsp_query-from>
      <Hsp_query-to>2017</Hsp_query-to>
      <Hsp_hit-from>470</Hsp_hit-from>
      <Hsp_hit-to>932</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>164</Hsp_identity>
      <Hsp_positive>259</Hsp_positive>
      <Hsp_gaps>67</Hsp_gaps>
      <Hsp_align-len>521</Hsp_align-len>
      <Hsp_qseq>LYSHQLEGVAWLYNLFKNKRKGGILADDMGLGKTIQVISFLSGMFDASL-FGHVLLVMPTTLMSIWISEFDKWAPGITIREFYGTKSERTRNLQKVQRTQG--VVITSYQLLVNNWHELSTYQGHEFIWDAMILDEGXXXXXXXXXXXXXXXXXPAHF-----RMILTGTPVQNNLKEIWALFDFVCEGSLLGTSKTFKMEYENPITKARQKDATVGEKALGTRMAENLQELIGPYFLRRTKAEVQSKELHAKQLRDNKENDPTVGNLDQRIQIEMPTLTRKNDLIVWVYLSPVQEQIYRDFQNLDDIKELLDSTRSPLVALGILKKICVHPRLLPERACAQLGLNQQFGRIESEGLQSNWFLSSIKNVPPKTLIEESGKLTFLIGLLERLRQEGHRTLVFSQSLKMLDIIDHILKHQGFKVMRIDGTITHITEREKRVQTFQ-KDSAFNXXXXXXXXXXXXXXXXAANRVVILDPSWNPATDAQAVDRAYRIGQTDNVIIYRLVTCGTMEEKIYRRQIFK</Hsp_qseq>
      <Hsp_hseq>LKEYQLRGLEWMVSLYNN-HLNGILADEMGLGKTIQSISLITYLYEVKKDIGPFLVIVPLSTITNWTLEFEKWAPSLNTIIYKGTPNQR-HSLQHQIRVGNFDVLLTTYEYIIKDKSLLSKHD-----WAHMIIDEGHRMKNAQSKLSFTI----SHYYRTRNRLILTGTPLQNNLPELWALLNFVL-PKIFNSAKTFEDWFNTPFANTGTQEKLELTEEETLLIIRRLHKVLRPFLLRRLKKEVE------KDLPDKVEK-VIKCKLSGLQQQLYQQMLKHNALFVGAGTEGATKGGIKGLNN----------------KIMQLRKICNHP----------------FVFDEVEGVVNPSRGNS------DLLFRVAGKFELLDRVLPKFKASGHRVLMFFQMTQVMDIMEDFLRMKDLKYMRLDGS-TKTEERTEMLNAFNAPDSDYFCFLLSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTDSVEEVILERAMQK</Hsp_hseq>
      <Hsp_midline>L  +QL G+ W+ +L+ N    GILAD+MGLGKTIQ IS ++ +++     G  L+++P + ++ W  EF+KWAP +    + GT ++R  +LQ   R     V++T+Y+ ++ +   LS +      W  MI+DEGH++K + +K + +     +H+     R+ILTGTP+QNNL E+WAL +FV    +  ++KTF+  +  P      ++     +     +   L +++ P+ LRR K EV+      K L D  E       L    Q     + + N L V        +   +   N                 +  L+KIC HP                F   E EG+ +    +S        L   +GK   L  +L + +  GHR L+F Q  +++DI++  L+ +  K MR+DG+ T   ER + +  F   DS +  FLL+T+ GG+GL L  A+ V+I D  WNP  D QA DRA+RIGQ + V I RL+T  ++EE I  R + K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YFR038W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:229380:231941:1 gene:YFR038W transcript:YFR038W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IRC5 description:Putative ATPase containing the DEAD/H helicase-related sequence motif; null mutant displays increased levels of spontaneous Rad52p foci; SWAT-GFP and mCherry fusion proteins localize to the nucleus [Source:SGD;Acc:S000001934]</Hit_def>
  <Hit_accession>YFR038W</Hit_accession>
  <Hit_len>853</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>188.348</Hsp_bit-score>
      <Hsp_score>477</Hsp_score>
      <Hsp_evalue>5.50615e-50</Hsp_evalue>
      <Hsp_query-from>482</Hsp_query-from>
      <Hsp_query-to>2032</Hsp_query-to>
      <Hsp_hit-from>222</Hsp_hit-from>
      <Hsp_hit-to>749</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>160</Hsp_identity>
      <Hsp_positive>273</Hsp_positive>
      <Hsp_gaps>53</Hsp_gaps>
      <Hsp_align-len>549</Hsp_align-len>
      <Hsp_qseq>LYSHQLEGVAWLYNLFKNKRKGGILADDMGLGKTIQVISFLSGMFDASLFGHVLLVMPTTLMSIWISEFDKWAPGITIREFYGT-----KSERTRNLQKVQRTQGVVITSYQLLVNNWHELSTYQGHEFIWDAMILDEGXXXXXXXXXXXXXXXXXPAHFRMILTGTPVQNNLKEIWALFDFVCEGSLLGTSKTFKMEYE-NPITKARQKDATVGEK----ALGTRMAENLQELIGPYFLRRTKAEVQSKELHAKQLRDNKENDPTVGNLDQRIQIEMPTLTRKNDLIVWVYLSPVQEQIYRDFQNLDD----------IKELLDSTRSPLVALGILKKICVHPRLLPERACAQLGLNQQFG--RIESEGLQ-----SNWFLSSIKNVPPKTL-----IEESGKLTFLIGLLERLRQEGHRTLVFSQSLKMLDIIDHILKHQGFKVMRIDGTITHITEREKRVQTFQKDSAFNXXXXXXXXXXXXXXXXAANRVVILDPSWNPATDAQAVDRAYRIGQTDNVIIYRLVTCGTMEEKIYRRQIFKESLIR</Hsp_qseq>
      <Hsp_hseq>LKPYQLEGLNWLITLYENGL-NGILADEMGLGKTVQSIALLAFIYEMDTKGPFLVTAPLSTLDNWMNEFAKFAPDLPVLKYYGTNGYKERSAKLKNFFKQHGGTGIVITSYEIILRDTDLIMSQN-----WKFLIVDEGHRLKNINCRLIKELKKINTSNRLLLTGTPLQNNLAELWSLLNFIMP-DIFADFEIFNKWFDFDSLNLGSGSNSEALNKLINDELQKNLISNLHTILKPFLLRRLKKVVLANILPPK--REYIINCPMTSAQEKFYKAGLNGKLKK----------TMFKELIKDFFTLNDEYIGHVSNRSIRDFINYKLSGNETSNTDNKI--NPTLLQMDKLYKKNLQMEISNKKLQNMMMQLRQIIDSTFLFYFPYLHPEDLTLETLLKTSGKLQILQKLIPPLISEGHKVLIYSQFVNMLDLIEDWCDLNSFATFRIDGSVNNETRKDQLEKFNSSKDKHNIFLLSTRAAGLGINLVGADTVVLFDSDWNPQVDLQAMDRCHRIGQESPVIVYRLCCDNTIEHVILTRAANKRNLER</Hsp_hseq>
      <Hsp_midline>L  +QLEG+ WL  L++N    GILAD+MGLGKT+Q I+ L+ +++    G  L+  P + +  W++EF K+AP + + ++YGT     +S + +N  K     G+VITSY++++ +   + +       W  +I+DEGH++K  + +  K    I    R++LTGTP+QNNL E+W+L +F+    +    + F   ++ + +      ++    K     L   +  NL  ++ P+ LRR K  V +  L  K  R+   N P     ++  +  +    +K           + +++ +DF  L+D          I++ ++   S         KI  +P LL      +  L  +    ++++  +Q      + FL     + P+ L     ++ SGKL  L  L+  L  EGH+ L++SQ + MLD+I+       F   RIDG++ + T +++  +        N+FLL+T+  G+G+ L  A+ VV+ D  WNP  D QA+DR +RIGQ   VI+YRL    T+E  I  R   K +L R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YAL019W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:114919:118314:1 gene:YAL019W transcript:YAL019W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUN30 description:Snf2p family member with ATP-dependent chromatin remodeling activity; has a role in silencing at the mating type locus, telomeres and centromeres; enriched at centromeres and is required for correct chromatin structure around centromeres, as well as at the boundary element of the silent HMR; recruited to DNA double-strand breaks (DSBs) where it promotes 5&apos; strand resection of DSBs; potential Cdc28p substrate [Source:SGD;Acc:S000000017]</Hit_def>
  <Hit_accession>YAL019W</Hit_accession>
  <Hit_len>1131</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>188.348</Hsp_bit-score>
      <Hsp_score>477</Hsp_score>
      <Hsp_evalue>1.55825e-49</Hsp_evalue>
      <Hsp_query-from>482</Hsp_query-from>
      <Hsp_query-to>2056</Hsp_query-to>
      <Hsp_hit-from>572</Hsp_hit-from>
      <Hsp_hit-to>1103</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>170</Hsp_identity>
      <Hsp_positive>288</Hsp_positive>
      <Hsp_gaps>89</Hsp_gaps>
      <Hsp_align-len>573</Hsp_align-len>
      <Hsp_qseq>LYSHQLEGVAWLYNLFKNKRKGGILADDMGLGKTIQVISFLSGMFDASLFGHVLLVMPTTLMSIWISEFDKWAPGITIREFYGTKSERTRNLQKVQRTQG---VVITSYQLLVNNWHELSTYQGHEFIWDAMILDEGXXXXXXXXXXXXXXXXXPAHFRMILTGTPVQNNLKEIWALFDFVCEGSLLGTSKTFKMEYENPITKARQKDATVGEKALGTRMA-ENLQELIGPYFLRRTKAEVQSKELHAKQLRDNKENDPTVGNLDQRIQIEMPTLTRKNDLIVWVYLSPVQEQIY-RDFQNLDDIKELLDSTRSPLVA--------------LGILKKICVHPRL-----------------LPERACAQLGLNQQFGRIESEGLQSNWFLSSIKNVPPKTLIE---------ESGKLTFLIGLLERL---RQEGHRTLVFSQSLKMLDIIDHILKHQGFKVMRIDGTITHITEREKRVQTFQKDSAFNXXXXXXXXXXXXXXXXAANRVVILDPSWNPATDAQAVDRAYRIGQTDNVIIYRLVTCGTMEEKIYRRQIFKESLIRQTTGDKKN</Hsp_qseq>
      <Hsp_hseq>LKDYQQTGINWLNLLYQNKM-SCILADDMGLGKTCQVISFFAYLKQINEPGPHLVVVPSSTLENWLREFQKFAPALKIEPYYGSLQEREELRDILERNAGKYDVIVTTYNLAAGNKYDVSFLKNRNF--NVVVYDEGHMLKNSTSERFAKLMKIRANFRLLLTGTPLQNNLKELMSLLEFIMPNLFISKKESFDAIFKQ---RAKTTDDNKNHNPLLAQEAITRAKTMMKPFILRRRKDQV------------------------------LKHLPPKHTHIQYCELNAIQKKIYDKEIQIVLEHKRMIKDGELPKDAKEKSKLQSSSSKNLIMALRKASLHPLLFRNIYNDKIITKMSDAILDEPAYAENG-NKEYIK-EDMSYMTDFELHKLCCNFPNTLSKYQLHNDEWMQSGKIDALKKLLKTIIVDKQE--KVLIFSLFTQVLDILEMVLSTLDYKFLRLDGS-TQVNDRQLLIDKFYEDKDIPIFILSTKAGGFGINLVCANNVIIFDQSFNPHDDRQAADRAHRVGQTKEVNITTLITKDSIEEKIHQLAKNKLALDSYISEDKKS</Hsp_hseq>
      <Hsp_midline>L  +Q  G+ WL  L++NK    ILADDMGLGKT QVISF + +   +  G  L+V+P++ +  W+ EF K+AP + I  +YG+  ER      ++R  G   V++T+Y L   N +++S  +   F  + ++ DEGH +K S+++       I A+FR++LTGTP+QNNLKE+ +L +F+     +   ++F   ++    +A+  D       L  + A    + ++ P+ LRR K +V                              +  L  K+  I +  L+ +Q++IY ++ Q + + K ++     P  A              +  L+K  +HP L                 L E A A+ G N+++ + E     +++ L  +    P TL +         +SGK+  L  LL+ +   +QE  + L+FS   ++LDI++ +L    +K +R+DG+ T + +R+  +  F +D    +F+L+T+ GG G+ L  AN V+I D S+NP  D QA DRA+R+GQT  V I  L+T  ++EEKI++    K +L    + DKK+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YBR245C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:708150:711539:-1 gene:YBR245C transcript:YBR245C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ISW1 description:ATPase subunit of imitation-switch (ISWI) class chromatin remodelers; with Ioc3p forms Isw1a complex involved in repression of transcription initiation; with Ioc2p and Ioc4p forms Isw1b complex involved in regulation of transcription elongation; Isw1b recruited to ORFs by H3K36 methylation and acts with Chd1p to prevent trans-histone exchange over coding regions; Isw1p import into nucleus depends on C-terminal bipartite nuclear targeting signal KRIR X19 KKAK [Source:SGD;Acc:S000000449]</Hit_def>
  <Hit_accession>YBR245C</Hit_accession>
  <Hit_len>1129</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>187.193</Hsp_bit-score>
      <Hsp_score>474</Hsp_score>
      <Hsp_evalue>4.11369e-49</Hsp_evalue>
      <Hsp_query-from>470</Hsp_query-from>
      <Hsp_query-to>2005</Hsp_query-to>
      <Hsp_hit-from>192</Hsp_hit-from>
      <Hsp_hit-to>639</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>166</Hsp_identity>
      <Hsp_positive>265</Hsp_positive>
      <Hsp_gaps>96</Hsp_gaps>
      <Hsp_align-len>528</Hsp_align-len>
      <Hsp_qseq>LHNQLYSHQLEGVAWLYNLFKNKRKGGILADDMGLGKTIQVISFLSGM-FDASLFGHVLLVMPTTLMSIWISEFDKWAPGITIREFYGTKSERTRNLQK--VQRTQGVVITSYQLLVNNWHELSTYQGHEFIWDAMILDEGXXXXXXXXXXXXXXXXXPAHFRMILTGTPVQNNLKEIWALFDFVCEGSLLGTSKTFKMEYENPITKARQKDATVGEKALGTRMAENLQELIGPYFLRRTKAEVQSKELHAKQLRDNKENDPTVGNLDQRIQIEMPTLTRKNDLIVWVYLSPVQEQIYRDF--QNLDDIKELLDSTRSPLVALGI---LKKICVHPRLLPERACAQLGLNQQFGRIESEGLQSNWFLSSIKNVPPKT----LIEESGKLTFLIGLLERLRQEGHRTLVFSQSLKMLDIIDHILKHQGFKVMRIDGTITHITEREKRVQTFQ----KDSAFNXXXXXXXXXXXXXXXXAANRVVILDPSWNPATDAQAVDRAYRIGQTDNVIIYRLVTCGTMEEKIYRR</Hsp_qseq>
      <Hsp_hseq>VNGQLRPYQIQGVNWLVSLHKNK-IAGILADEMGLGKTLQTISFLGYLRYIEKIPGPFLVIAPKSTLNNWLREINRWTPDVNAFILQGDKEERAELIQKKLLGCDFDVVIASYEIIIREKSPLKKIN-----WEYIIIDEAHRIKNEESMLSQVLREFTSRNRLLITGTPLQNNLHELWALLNFLLP-DIFSDAQDFDDWFSSESTEEDQ-----------DKIVKQLHTVLQPFLLRRIKSDVET------------------------------SLLPKKELNLYVGMSSMQKKWYKKILEKDLDAVNGSNGSKESKTRLLNIMMQLRKCCNHPYLF---DGAEPG-------------------------PPYTTDEHLVYNAAKLQVLDKLLKKLKEEGSRVLIFSQMSRLLDILEDYCYFRNYEYCRIDGSTAH----EDRIQAIDDYNAPDSKKFVFLLTTRAGGLGINLTSADVVVLYDSDWNPQADLQAMDRAHRIGQKKQVKVFRLVTDNSVEEKILER</Hsp_hseq>
      <Hsp_midline>++ QL  +Q++GV WL +L KNK   GILAD+MGLGKT+Q ISFL  + +   + G  L++ P + ++ W+ E ++W P +      G K ER   +QK  +     VVI SY++++     L         W+ +I+DE H+IK   +  ++      +  R+++TGTP+QNNL E+WAL +F+    +   ++ F   + +  T+  Q            ++ + L  ++ P+ LRR K++V++                              +L  K +L ++V +S +Q++ Y+    ++LD +     S  S    L I   L+K C HP L      A+ G                         PP T    L+  + KL  L  LL++L++EG R L+FSQ  ++LDI++     + ++  RIDG+  H    E R+Q        DS   VFLLTT+ GG+G+ LT+A+ VV+ D  WNP  D QA+DRA+RIGQ   V ++RLVT  ++EEKI  R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YER164W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:505392:509798:1 gene:YER164W transcript:YER164W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHD1 description:Chromatin remodeler that regulates various aspects of transcription; acts in in conjunction with Isw1b to regulate chromatin structure and maintain chromatin integrity during transcription elongation by RNAP II by preventing trans-histone exchange over coding regions; contains a chromo domain, a helicase domain and a DNA-binding domain; component of both the SAGA and SLIK complexes [Source:SGD;Acc:S000000966]</Hit_def>
  <Hit_accession>YER164W</Hit_accession>
  <Hit_len>1468</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>187.193</Hsp_bit-score>
      <Hsp_score>474</Hsp_score>
      <Hsp_evalue>6.36093e-49</Hsp_evalue>
      <Hsp_query-from>479</Hsp_query-from>
      <Hsp_query-to>2005</Hsp_query-to>
      <Hsp_hit-from>375</Hsp_hit-from>
      <Hsp_hit-to>832</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>164</Hsp_identity>
      <Hsp_positive>257</Hsp_positive>
      <Hsp_gaps>105</Hsp_gaps>
      <Hsp_align-len>536</Hsp_align-len>
      <Hsp_qseq>QLYSHQLEGVAWLYNLFKNKRKGGILADDMGLGKTIQVISFLSGM-FDASLFGHVLLVMPTTLMSIWISEFDKWAPGITIREFYGTKSER---------TRNLQKVQRTQ--GVVITSYQLLVNNWHELSTYQGHEFIWDAMILDEGXXXXXXXXXXXXXXXXXPAHFRMILTGTPVQNNLKEIWALFDFVCEGSLLGTSKTFKMEYENPITKARQKDATVGEKALGTRMAENLQELIGPYFLRRTKAEVQSKELHAKQLRDNKENDPTVGNLDQRIQIEMPTLTRKNDLIVWVYLSPVQEQIYRDFQNLDDIKELLDSTRSPLVA------------LGILKKICVHPRLL---PERACAQLGLNQQFGRIESEGLQSNWFLSSIKNVPPKTLIEESGKLTFLIGLLERLRQEGHRTLVFSQSLKMLDIIDHILKHQGFKVMRIDGTITHITEREKRVQTFQKDSAFNXXXXXXXXXXXXXXXXAANRVVILDPSWNPATDAQAVDRAYRIGQTDNVIIYRLVTCGTMEEKIYRR</Hsp_qseq>
      <Hsp_hseq>ELRDFQLTGINWMAFLW-SKGDNGILADEMGLGKTVQTVAFISWLIFARRQNGPHIIVVPLSTMPAWLDTFEKWAPDLNCICYMGNQKSRDTIREYEFYTNPRAKGKKTMKFNVLLTTYEYILKDRAELGSIK-----WQFMAVDEAHRLKNAESSLYESLNSFKVANRMLITGTPLQNNIKELAALVNFLMPGRFTIDQE---IDFENQDEEQEE-------------YIHDLHRRIQPFILRRLKKDVEK------------------------------SLPSKTERILRVELSDVQTEYY---------KNILTKNYSALTAGAKGGHFSLLNIMNELKKASNHPYLFDNAEERVLQKFG----DGKMTRENVL-------------RGLIMSSGKMVLLDQLLTRLKKDGHRVLIFSQMVRMLDILGDYLSIKGINFQRLDGTVPSAQRRISIDHFNSPDSNDFVFLLSTRAGGLGINLMTADTVVIFDSDWNPQADLQAMARAHRIGQKNHVMVYRLVSKDTVEEEVLER</Hsp_hseq>
      <Hsp_midline>+L   QL G+ W+  L+ +K   GILAD+MGLGKT+Q ++F+S + F     G  ++V+P + M  W+  F+KWAP +    + G +  R         T    K ++T    V++T+Y+ ++ +  EL + +     W  M +DE H++K + +   +S ++     RM++TGTP+QNN+KE+ AL +F+  G      +   +++EN   +  +                +L   I P+ LRR K +V+                               +L  K + I+ V LS VQ + Y         K +L    S L A            +  LKK   HP L     ER   + G     G++  E +              + LI  SGK+  L  LL RL+++GHR L+FSQ ++MLDI+   L  +G    R+DGT+     R         DS   VFLL+T+ GG+G+ L  A+ VVI D  WNP  D QA+ RA+RIGQ ++V++YRLV+  T+EE++  R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YBR073W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:383112:385988:1 gene:YBR073W transcript:YBR073W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RDH54 description:DNA-dependent ATPase; DNA recombination/repair translocase, supercoils DNA and promotes DNA strand opening; stimulates strand exchange by modifying dsDNA topology; involved in recombinational repair of DNA double-strand breaks (DSBs) during mitosis and meiosis; phosphorylated in Mec1p-, Rad53p-dependent way in response to one DSB; contributes to remodelling of nucleosomes; proposed to be involved in crossover interference; interacts with Dmc1p; stimulates Dmc1p and Rad51p [Source:SGD;Acc:S000000277]</Hit_def>
  <Hit_accession>YBR073W</Hit_accession>
  <Hit_len>958</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>180.644</Hsp_bit-score>
      <Hsp_score>457</Hsp_score>
      <Hsp_evalue>2.95343e-47</Hsp_evalue>
      <Hsp_query-from>482</Hsp_query-from>
      <Hsp_query-to>2122</Hsp_query-to>
      <Hsp_hit-from>296</Hsp_hit-from>
      <Hsp_hit-to>847</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>176</Hsp_identity>
      <Hsp_positive>285</Hsp_positive>
      <Hsp_gaps>135</Hsp_gaps>
      <Hsp_align-len>617</Hsp_align-len>
      <Hsp_qseq>LYSHQLEGVAWLYNLFKNKRK------------------------GGILADDMGLGKTIQVISFL-----------------SGMFDASLFGHVLLVMPTTLMSIWISEFDKW-------APGITIREFYGTKSERTRNLQKVQRTQGVVITSYQLLVNNWHELSTYQGHEFIWDAMILDEGXXXXXXXXXXXXXXXXXPAHFRMILTGTPVQNNLKEIWALFDFVCEGSLLGTSKTFKMEYENPITKARQKDATVGEKAL--GTRMAENLQELIGPYFLRRTKAEVQSKELHAKQLRDNKENDPTVGNLDQRIQIEMPTLTRKNDLIVWVYLSPVQEQIYRDFQNLDDIKELLDSTR---------SPLVALGILKKICVHPRLLPERACAQLGLNQQFGRIESEGLQSNWFLSSIKNVPPKTLIE---ESGKLTFLIGLLERLRQ-EGHRTLVFSQSLKMLDIIDHILKHQGFKVMRIDGTITHITEREKRVQTFQKDSAFNXXXXXXXXXXXXXXXXAANRVVILDPSWNPATDAQAVDRAYRIGQTDNVIIYRLVTCGTMEEKIYRRQIFKESLIRQTTGDKKNPFR------YFSQQELRELF-ILEDTKSS</Hsp_qseq>
      <Hsp_hseq>LRPHQREGVKFMYDCLMGLARPTIENPDIDCTTKSLVLENDSDISGCLLADDMGLGKTLMSITLIWTLIRQTPFASKVSCSQSGIPLTGLCKKILVVCPVTLIGNWKREFGKWLNLSRIGVLTLSSRNSPDMDKMAVRNFLKVQRTYQVLIIGYEKLLSVSEEL---EKNKHLIDMLVCDEGHRLKNGASKILNTLKSLDIRRKLLLTGTPIQNDLNEFFTIIDFINPG-ILGSFASFKRRFIIPITRARDTANRYNEELLEKGEERSKEMIEITKRFILRRTNAILEK------------------------------YLPPKTDIIL--FCKPYSQQILA-------FKDILQGARLDFGQLTFSSSLGLITLLKKVCNSP-----------------GLVGSDP----YYKSHIKDTQSQDSYSRSLNSGKLKVLMTLLEGIRKGTKEKVVVVSNYTQTLDIIENLMNMAGMSHCRLDGSIPA-KQRDSIVTSFNRNPAIFGFLLSAKSGGVGLNLVGASRLILFDNDWNPSVDLQAMSRIHRDGQKKPCFIYRLVTTGCIDEKILQRQLMKNSLSQKFLGDSEMRNKESSNDDLFNKEDLKDLFSVHTDTKSN</Hsp_hseq>
      <Hsp_midline>L  HQ EGV ++Y+      +                        G +LADDMGLGKT+  I+ +                 SG+    L   +L+V P TL+  W  EF KW          ++ R          RN  KVQRT  V+I  Y+ L++   EL   + ++ + D ++ DEGH++K  ++K   +  ++    +++LTGTP+QN+L E + + DF+  G +LG+  +FK  +  PIT+AR       E+ L  G   ++ + E+   + LRRT A ++                                L  K D+I+  +  P  +QI          K++L   R         S L  + +LKK+C  P                 G + S+     ++ S IK+   +        SGKL  L+ LLE +R+    + +V S   + LDII++++   G    R+DG+I    +R+  V +F ++ A   FLL+ + GGVGL L  A+R+++ D  WNP+ D QA+ R +R GQ     IYRLVT G ++EKI +RQ+ K SL ++  GD +   +       F++++L++LF +  DTKS+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YDR334W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1135932:1140476:1 gene:YDR334W transcript:YDR334W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWR1 description:Swi2/Snf2-related ATPase; structural component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; relocalizes to the cytosol in response to hypoxia; chronological aging factor that mediates lifespan extension by dietary restriction [Source:SGD;Acc:S000002742]</Hit_def>
  <Hit_accession>YDR334W</Hit_accession>
  <Hit_len>1514</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>145.206</Hsp_bit-score>
      <Hsp_score>365</Hsp_score>
      <Hsp_evalue>9.45968e-36</Hsp_evalue>
      <Hsp_query-from>470</Hsp_query-from>
      <Hsp_query-to>1471</Hsp_query-to>
      <Hsp_hit-from>692</Hsp_hit-from>
      <Hsp_hit-to>1002</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>105</Hsp_identity>
      <Hsp_positive>164</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>347</Hsp_align-len>
      <Hsp_qseq>LHNQLYSHQLEGVAWLYNLFKNKRKGGILADDMGLGKTIQVISFLSGM-FDASLFGHVLLVMPTTLMSIWISEFDKWAPGITIREFYGTKSERTRNLQKVQRTQG--VVITSYQLLVNNWHELSTYQGHEFIWDAMILDEGXXXXXXXXXXXXXXXXXPAHFRMILTGTPVQNNLKEIWALFDFVCEGSLLGTSK--------TFKMEYENPITKARQKDATVGEKALGTRMAENLQELIGPYFLRRTKAEVQSKELHAKQLRDNKENDPTVGNLDQRIQIEMPTLTRKNDLIVWVYLSPVQEQIYRDFQNLDDIKELLDSTR--SPLVALGILKKICVHPRLLPER</Hsp_qseq>
      <Hsp_hseq>LRGNLRTYQKQGLNWLASLYNN-HTNGILADEMGLGKTIQTISLLAYLACEKENWGPHLIVVPTSVLLNWEMEFKRFAPGFKVLTYYGSPQQRKEKRKGWNKPDAFHVCIVSYQLVVQDQHSFKRKR-----WQYMVLDEAHNIKNFRSTRWQALLNFNTQRRLLLTGTPLQNNLAELWSLLYFLMPQTVIDGKKVSGFADLDAFQQWFGRPVDKIIETGQNFGQDKETKKTVAKLHQVLRPYLLRRLKADVEK---------------------------QMPA---KYEHIVYCKLSKRQRFLYDDFMSRAQTKATLASGNFMSIVNCLMQLRKVCNHPNLFEVR</Hsp_hseq>
      <Hsp_midline>L   L ++Q +G+ WL +L+ N    GILAD+MGLGKTIQ IS L+ +  +   +G  L+V+PT+++  W  EF ++APG  +  +YG+  +R    +   +     V I SYQL+V + H     +     W  M+LDE H IK   +   ++        R++LTGTP+QNNL E+W+L  F+   +++   K         F+  +  P+ K  +     G+     +    L +++ PY LRR KA+V+                            +MP    K + IV+  LS  Q  +Y DF +    K  L S    S +  L  L+K+C HP L   R</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>106.301</Hsp_bit-score>
      <Hsp_score>264</Hsp_score>
      <Hsp_evalue>1.08073e-23</Hsp_evalue>
      <Hsp_query-from>1565</Hsp_query-from>
      <Hsp_query-to>2098</Hsp_query-to>
      <Hsp_hit-from>1236</Hsp_hit-from>
      <Hsp_hit-to>1413</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>179</Hsp_align-len>
      <Hsp_qseq>PPKTLIE-ESGKLTFLIGLLERLRQEGHRTLVFSQSLKMLDIIDHILKHQGFKVMRIDGTITHITEREKRVQTFQKDSAFNXXXXXXXXXXXXXXXXAANRVVILDPSWNPATDAQAVDRAYRIGQTDNVIIYRLVTCGTMEEKIYRRQIFKESLIRQTTGDKKNPFRYFSQQELRELF</Hsp_qseq>
      <Hsp_hseq>PDKSLLQYDCGKLQKLAILLQQLKDNGHRALIFTQMTKVLDVLEQFLNYHGYLYMRLDGA-TKIEDRQILTERFNTDSRITVFILSSRSGGLGINLTGADTVIFYDSDWNPAMDKQCQDRCHRIGQTRDVHIYRFVSEHTIESNILKKANQKRQLDNVVIQEGDFTTDYFSKLSVRDLL</Hsp_hseq>
      <Hsp_midline>P K+L++ + GKL  L  LL++L+  GHR L+F+Q  K+LD+++  L + G+  MR+DG  T I +R+   + F  DS   VF+L+++ GG+G+ LT A+ V+  D  WNPA D Q  DR +RIGQT +V IYR V+  T+E  I ++   K  L      +      YFS+  +R+L </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YGL150C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:221104:225573:-1 gene:YGL150C transcript:YGL150C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:INO80 description:ATPase and nucleosome spacing factor; subunit of complex containing actin and actin-related proteins that has chromatin remodeling activity and 3&apos; to 5&apos; DNA helicase activity in vitro; promotes nucleosome shifts in the 3 prime direction; has a role in modulating stress gene transcription [Source:SGD;Acc:S000003118]</Hit_def>
  <Hit_accession>YGL150C</Hit_accession>
  <Hit_len>1489</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>120.553</Hsp_bit-score>
      <Hsp_score>301</Hsp_score>
      <Hsp_evalue>4.53783e-28</Hsp_evalue>
      <Hsp_query-from>482</Hsp_query-from>
      <Hsp_query-to>1198</Hsp_query-to>
      <Hsp_hit-from>706</Hsp_hit-from>
      <Hsp_hit-to>942</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>136</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>249</Hsp_align-len>
      <Hsp_qseq>LYSHQLEGVAWLYNLFKNKRKGGILADDMGLGKTIQVISFLSGMFDA-SLFGHVLLVMPTTLMSIWISEFDKWAPGITIREFYGTKSERT--------RNLQKVQRTQ-GVVITSYQLLVNNWHELSTYQGHEFIWDAMILDEGXXXXXXXXXXXXXXXXXPAHFRMILTGTPVQNNLKEIWALFDFVCEGSLLGTSKTFKMEYENPITKARQKDATVGEKALGTRMAENLQELIGPYFLRRTKAEVQS</Hsp_qseq>
      <Hsp_hseq>LKEYQLKGLNWLANLY-DQGINGILADEMGLGKTVQSISVLAHLAENHNIWGPFLVVTPASTLHNWVNEISKFLPQFKILPYWGNANDRKVLRKFWDRKNLRYNKNAPFHVMVTSYQMVVTDANYLQKMK-----WQYMILDEAQAIKSSQSSRWKNLLSFHCRNRLLLTGTPIQNSMQELWALLHFIMP-SLFDSHDEFNEWFSKDIESHAEANTKLNQQQL-----RRLHMILKPFMLRRVKKNVQS</Hsp_hseq>
      <Hsp_midline>L  +QL+G+ WL NL+ ++   GILAD+MGLGKT+Q IS L+ + +  +++G  L+V P + +  W++E  K+ P   I  ++G  ++R         +NL+  +     V++TSYQ++V + + L   +     W  MILDE   IK+S +   K+  +     R++LTGTP+QN+++E+WAL  F+   SL  +   F   +   I    + +  + ++ L       L  ++ P+ LRR K  VQS</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>99.3673</Hsp_bit-score>
      <Hsp_score>246</Hsp_score>
      <Hsp_evalue>1.4805e-21</Hsp_evalue>
      <Hsp_query-from>1520</Hsp_query-from>
      <Hsp_query-to>2026</Hsp_query-to>
      <Hsp_hit-from>1276</Hsp_hit-from>
      <Hsp_hit-to>1442</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>169</Hsp_align-len>
      <Hsp_qseq>EGLQSNWFLSSIKNVPPKTLIEESGKLTFLIGLLERLRQEGHRTLVFSQSLKMLDIIDHILKHQGFKVMRIDGTITHITEREKRVQTFQKDSAFNXXXXXXXXXXXXXXXXAANRVVILDPSWNPATDAQAVDRAYRIGQTDNVIIYRLVTCGTMEEKIYRRQIFKESL</Hsp_qseq>
      <Hsp_hseq>EPLNKN-FSSNISMPSMDRFITESAKLRKLDELLVKLKSEGHRVLIYFQMTKMMDLMEEYLTYRQYNHIRLDGS-SKLEDRRDLVHDWQTNPEIFVFLLSTRAGGLGINLTAADTVIFYDSDWNPTIDSQAMDRAHRLGQTRQVTVYRLLVRGTIEERMRDRAKQKEQV</Hsp_hseq>
      <Hsp_midline>E L  N F S+I        I ES KL  L  LL +L+ EGHR L++ Q  KM+D+++  L ++ +  +R+DG+ + + +R   V  +Q +    VFLL+T+ GG+G+ LTAA+ V+  D  WNP  D+QA+DRA+R+GQT  V +YRL+  GT+EE++  R   KE +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YOR191W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:692475:697334:1 gene:YOR191W transcript:YOR191W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ULS1 description:Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL); required for maintenance of NHEJ inhibition at telomeres; functions at telomeres to translocate and ubiquitinylate poly-sumoylated Rap1p for proteosomal degradation; plays role in antagonizing silencing during mating-type switching; only known STUbL with a translocase activity; contains RING finger domain; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005717]</Hit_def>
  <Hit_accession>YOR191W</Hit_accession>
  <Hit_len>1619</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.0333</Hsp_bit-score>
      <Hsp_score>201</Hsp_score>
      <Hsp_evalue>3.09322e-16</Hsp_evalue>
      <Hsp_query-from>482</Hsp_query-from>
      <Hsp_query-to>1015</Hsp_query-to>
      <Hsp_hit-from>943</Hsp_hit-from>
      <Hsp_hit-to>1154</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>213</Hsp_align-len>
      <Hsp_qseq>LYSHQLEGVAWLYNLFKNKRKGGILADDMGLGKTIQVISF-LSGMFDASLFGHVLLVMPTTLMSIWISEFD---KWAPGITIREFYGTKSERTRNLQKVQRTQGVVITSYQLLVN----NW--------------------HELST---YQGHEFIWDA----MILDEGXXXXXXXXXXXXXXXXXPAHFRMILTGTPVQNNLKEIWALFDFV</Hsp_qseq>
      <Hsp_hseq>LLKHQRLGLHWLLQVENSAKKGGLLADDMGLGKTIQAIALMLANRSEESKCKTNLIVAPVSVLRVWKGELETKVKKRAKFTTFIFGGSGNGKVKHWRDLARYDAVLV-SYQTLANEFKKHWPKKLDGEQNQLPAVPHIQALNRLKTSNEYYSPFFCNDSTFYRILLDEGQNIKNKNTRASKACCTINGMYRWVLSGTPIQNSMDELYSLIRFL</Hsp_hseq>
      <Hsp_midline>L  HQ  G+ WL  +  + +KGG+LADDMGLGKTIQ I+  L+   + S     L+V P +++ +W  E +   K     T   F G+ + + ++ + + R   V++ SYQ L N    +W                    + L T   Y    F  D+    ++LDEG  IK  +T+ +K+   I   +R +L+GTP+QN++ E+++L  F+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>4.46253e-13</Hsp_evalue>
      <Hsp_query-from>1529</Hsp_query-from>
      <Hsp_query-to>2029</Hsp_query-to>
      <Hsp_hit-from>1428</Hsp_hit-from>
      <Hsp_hit-to>1590</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>170</Hsp_align-len>
      <Hsp_qseq>QSNWFLSSIKNVPPKTLIEESGKLTFLIGLLERLRQEG--HRTLVFSQSLKMLDIIDHILKHQ-GFKVMRIDGTITHITEREKRVQTFQKDSAFNXXXXXXXXXXXXXXXXAANRVVILDPSWNPATDAQAVDRAYRIGQTDNVIIYRLVTCGTMEEKIYRRQIFKESLI</Hsp_qseq>
      <Hsp_hseq>QKNVYVPNFESLEPSTKIEQ------CIQVIQRVFDESATEKIIIFSQFTTFFEILEHFLKNKLNFPYLKYIGSM-NAQRRSDVINEFYRDPEKRILLISMKAGNSGLTLTCANHVVIVDPFWNPYVEEQAQDRCYRISQTKKVQVHKLFIKDSVEDRISELQKRKKEMV</Hsp_hseq>
      <Hsp_midline>Q N ++ + +++ P T IE+       I +++R+  E    + ++FSQ     +I++H LK++  F  ++  G++ +   R   +  F +D    + L++ + G  GLTLT AN VVI+DP WNP  + QA DR YRI QT  V +++L    ++E++I   Q  K+ ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YBR114W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:467248:469620:1 gene:YBR114W transcript:YBR114W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD16 description:Nucleotide excision repair (NER) protein; binds damaged DNA during NER; binds DNA in an ATP-dependent manner (with Rad7p) during NER; required for NER of non-transcribed chromatin; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex [Source:SGD;Acc:S000000318]</Hit_def>
  <Hit_accession>YBR114W</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.0998</Hsp_bit-score>
      <Hsp_score>183</Hsp_score>
      <Hsp_evalue>3.31509e-14</Hsp_evalue>
      <Hsp_query-from>1583</Hsp_query-from>
      <Hsp_query-to>2098</Hsp_query-to>
      <Hsp_hit-from>616</Hsp_hit-from>
      <Hsp_hit-to>788</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>174</Hsp_align-len>
      <Hsp_qseq>EESGKLTFLIGLLERLRQEGH--RTLVFSQSLKMLDIIDHILKHQGFKVMRIDGTITHITEREKRVQTFQKDSAFNXXXXXXXXXXXXXXXXAANRVVILDPSWNPATDAQAVDRAYRIGQTDNVIIYRLVTCGTMEEKIYRRQIFKESLIRQTTGDKKNPFRYFSQQELRELF</Hsp_qseq>
      <Hsp_hseq>QSSTKIEALVEELYKLRSNKRTIKSIVFSQFTSMLDLVEWRLKRAGFQTVKLQGSMSP-TQRDETIKYFMNNIQCEVFLVSLKAGGVALNLCEASQVFILDPWWNPSVEWQSGDRVHRIGQYRPVKITRFCIEDSIEARIIELQEKKANMIHATINQDEAAISRLTPADLQFLF</Hsp_hseq>
      <Hsp_midline>+ S K+  L+  L +LR      +++VFSQ   MLD+++  LK  GF+ +++ G+++  T+R++ ++ F  +    VFL++ + GGV L L  A++V ILDP WNP+ + Q+ DR +RIGQ   V I R     ++E +I   Q  K ++I  T    +      +  +L+ LF</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>9.00982e-13</Hsp_evalue>
      <Hsp_query-from>479</Hsp_query-from>
      <Hsp_query-to>1189</Hsp_query-to>
      <Hsp_hit-from>183</Hsp_hit-from>
      <Hsp_hit-to>449</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>129</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>277</Hsp_align-len>
      <Hsp_qseq>QLYSHQLEGVAWLYNLFKNKRKGGILADDMGLGKTIQVISFLSGMFDASLFGHVLLVMPTTLMSIWISEFDKWAPG-ITIREFYGTKSERTRNLQKVQRTQGVVITSYQLLVNNWHE----LSTYQG--------HEFIWDAMILDEGXXXXXXXXXXXXXXXXXPAHFRMILTGTPVQNNLKEIWALFDFV------------CEGSLLGTSKTFK--------------MEYENPITKARQKD-ATVGEKALGTRMAENLQELIGPYFLRRTKAE</Hsp_qseq>
      <Hsp_hseq>KLLPFQLEGLHWLISQEESIYAGGVLADEMGMGKTIQTIALLMNDLTKS---PSLVVAPTVALMQWKNEIEQHTKGQLKIYIYHG--ASRTTDIKDLQ-GYDVVLTTYAVLESVFRKQNYGFRRKNGLFKQPSVLHNIDFYRVILDEAHNIKDRQSNTARAVNNLKTQKRWCLSGTPLQNRIGEMYSLIRFLNINPFTKYFCTKCDCA----SKDWKFTDRMHCDHCSHVIMQHTNFFNHFMLKNIQKFGVEGPGLESFNNIQTLLKNIMLRRTKVE</Hsp_hseq>
      <Hsp_midline>+L   QLEG+ WL +  ++   GG+LAD+MG+GKTIQ I+ L      S     L+V PT  +  W +E ++   G + I  ++G  + RT +++ +Q    VV+T+Y +L + + +         G        H   +  +ILDE H IK   + TA++ + +    R  L+GTP+QN + E+++L  F+            C+ +    SK +K              M++ N       K+    G +  G     N+Q L+    LRRTK E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YLR032W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:204991:208500:1 gene:YLR032W transcript:YLR032W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD5 description:DNA helicase/Ubiquitin ligase; involved in error-free DNA damage tolerance (DDT), replication fork regression during postreplication repair by template switching, error-prone translesion synthesis; promotes synthesis of free and PCNA-bound polyubiquitin chains by Ubc13p-Mms2p; forms nuclear foci upon DNA replication stress; associates with native telomeres, cooperates with homologous recombination in senescent cells; human homolog HLTF can complement yeast null mutant [Source:SGD;Acc:S000004022]</Hit_def>
  <Hit_accession>YLR032W</Hit_accession>
  <Hit_len>1169</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>1.4764e-11</Hsp_evalue>
      <Hsp_query-from>419</Hsp_query-from>
      <Hsp_query-to>1462</Hsp_query-to>
      <Hsp_hit-from>493</Hsp_hit-from>
      <Hsp_hit-to>848</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>97</Hsp_identity>
      <Hsp_positive>162</Hsp_positive>
      <Hsp_gaps>84</Hsp_gaps>
      <Hsp_align-len>394</Hsp_align-len>
      <Hsp_qseq>EDEYINVLGSGFNLYHELHNQLYSHQLEGVAWLYNLFKNKRKGGILADDMGLGKTIQVISFL------SGMFDASLFG------------------------HVLLVMPTTLMSIWISEFDKW--APGITIREFYGTK-SERTRNLQKVQRTQGVVITSYQLLVNNWHELSTYQGHEFIWDA-------------MILDEGXXXXXXXXXXXXXXXXXPAHFRMILTGTPVQNNLKEIWALFDFVCEGSLLGTSKTFKMEYENPITKARQKDATVGEKALGTRMAENLQELIGPYFLRRTKAEVQSKELHAKQLRDNKENDPTVGNLDQRIQIEMPTLTRKNDLIVWVYLSPVQEQIYRDFQNLDDIKELLDSTRSPLVALGILKKICVHPRLL</Hsp_qseq>
      <Hsp_hseq>QQDHVNV-EDGIFFYANLHSGEFS-------LAKPILKTMIKGGILSDEMGLGKTVAAYSLVLSCPHDSDVVDKKLFDIENTAVSDNLPSTWQDNKKPYASKTTLIVVPMSLLTQWSNEFTKANNSPDMYHEVYYGGNVSSLKTLLTKTKTPPTVVLTTYGIVQNEWTKHS--KGRMTDEDVNISSGLFSVNFYRIIIDEGHNIRNRTTVTSKAVMALQGKCKWVLTGTPIINRLDDLYSLVKFL-ELDPWRQINYWKTFVSTPFESKNYKQA-----------FDVVNAILEPVLLRRT-----------KQMKD-KDGKPLVELPPKEVVIKRLPFSKSQDLLYKFLLDKAEVSVKSGIARGD----LLKKYSTILVHILRLRQVCCHPGLI</Hsp_hseq>
      <Hsp_midline>+ +++NV   G   Y  LH+  +S           + K   KGGIL+D+MGLGKT+   S +      S + D  LF                           L+V+P +L++ W +EF K   +P +    +YG   S     L K +    VV+T+Y ++ N W + S  +G     D              +I+DEGH I+  +T T+K+  A+    + +LTGTP+ N L ++++L  F+ E         +K     P      K A            + +  ++ P  LRRT           KQ++D K+  P V    + + I+    ++  DL+    L   +  +       D    LL    + LV +  L+++C HP L+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>4.12887e-10</Hsp_evalue>
      <Hsp_query-from>1568</Hsp_query-from>
      <Hsp_query-to>2008</Hsp_query-to>
      <Hsp_hit-from>986</Hsp_hit-from>
      <Hsp_hit-to>1139</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>155</Hsp_align-len>
      <Hsp_qseq>PKTLIEESGKLTFLIGLLERLRQE--GHRTLVFSQSLKMLDIID----HILKHQGFKVMRIDGTITHITEREKRVQTFQ-KD-SAFNXXXXXXXXXXXXXXXXAANRVVILDPSWNPATDAQAVDRAYRIGQTDNVIIYRLVTCGTMEEKIYRRQ</Hsp_qseq>
      <Hsp_hseq>PYSPASKSSKITALLKELQLLQDSSAGEQVVIFSQFSTYLDILEKELTHTFSKDVAKIYKFDGRLS-LKERTSVLADFAVKDYSRQKILLLSLKAGGVGLNLTCASHAYMMDPWWSPSMEDQAIDRLHRIGQTNSVKVMRFIIQDSIEEKMLRIQ</Hsp_hseq>
      <Hsp_midline>P +   +S K+T L+  L+ L+    G + ++FSQ    LDI++    H       K+ + DG ++ + ER   +  F  KD S   + LL+ + GGVGL LT A+   ++DP W+P+ + QA+DR +RIGQT++V + R +   ++EEK+ R Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>1844704272</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052266-RA transcript Note:&quot;Similar to PLA2G3 Group 3 secretory phospholipase A2 (Homo sapiens)&quot; offset:0 AED:0.72 eAED:0.72 QI:0|0|0|0.5|0.66|0.5|4|0|104</Iteration_query-def>
  <Iteration_query-len>315</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>75</Statistics_hsp-len>
      <Statistics_eff-space>72572010</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052267-RA transcript Note:&quot;Similar to CIT Citron Rho-interacting kinase (Homo sapiens)&quot; offset:0 AED:0.34 eAED:0.34 QI:0|0.77|0.8|0.9|0.55|0.6|10|2264|375</Iteration_query-def>
  <Iteration_query-len>3392</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2321689010</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0026401-RA transcript Note:&quot;Similar to CIT Citron Rho-interacting kinase (Homo sapiens)&quot; offset:226 AED:0.16 eAED:0.16 QI:226|0.63|0.57|1|0.63|0.61|42|5748|684</Iteration_query-def>
  <Iteration_query-len>8029</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>168.318</Hsp_bit-score>
      <Hsp_score>425</Hsp_score>
      <Hsp_evalue>1.84818e-45</Hsp_evalue>
      <Hsp_query-from>494</Hsp_query-from>
      <Hsp_query-to>1342</Hsp_query-to>
      <Hsp_hit-from>64</Hsp_hit-from>
      <Hsp_hit-to>339</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>100</Hsp_identity>
      <Hsp_positive>153</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>289</Hsp_align-len>
      <Hsp_qseq>RVTSSDFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLVKGLLCGRVDRLTPD------KLLCHPFFAGIDWNNIQHSDDDT</Hsp_qseq>
      <Hsp_hseq>KYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLL-RKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEV---QTVTWTL-CGTPDYIAPEVITT----KPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKI--LQGKVVYP--PYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIET</Hsp_hseq>
      <Hsp_midline>+ T  DF++   +  G    V +VR    G  YA+KVL+K  ++    V    +ER +L     P+L  +   FQD  N+++V  Y  GG+L  LL R   +    + +FY AE++LA + LH    ++RDLKPEN+L+DR GHIK+ DFG A ++   + V+  L  G+PDY+APEV+++      Y    DWWS+GV+ YEM+ G TPF +    KT   I   Q  V +P  P    + VDL+  L+   + R   +       +  HP+F+ + W  +   D +T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>167.162</Hsp_bit-score>
      <Hsp_score>422</Hsp_score>
      <Hsp_evalue>6.4536e-45</Hsp_evalue>
      <Hsp_query-from>482</Hsp_query-from>
      <Hsp_query-to>1351</Hsp_query-to>
      <Hsp_hit-from>72</Hsp_hit-from>
      <Hsp_hit-to>372</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>106</Hsp_identity>
      <Hsp_positive>161</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>315</Hsp_align-len>
      <Hsp_qseq>LQELRVTSS-----DFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLVKGLLC-------GRVDRLTPDKLLCHPFFAGIDWNN-------------IQHSDDDTSNF</Hsp_qseq>
      <Hsp_hseq>IAQARVTSGKYSLQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLL-RKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPD---VTYTLC-GTPDYIAPEVVST----KPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAE--LRFP--PFFNEDVKDLLSRLITRDLSQRLGNLQNGTED-VKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGDTSQF</Hsp_hseq>
      <Hsp_midline>+ + RVTS      DF++   +  G    V ++R R  G  YAMKVL+K +++    V    +ER +L+  + P++  +   FQD   ++++  Y  GG+L  LL R   +    + +FY AE+ LA + LH    ++RDLKPEN+L+D+ GHIK+ DFG A  +     V+  L  G+PDY+APEV+S+      Y    DWWS G++ YEM+ G TPF +  + KT   I N +  +RFP  P  + +  DL+  L+        G +   T D +  HP+F  + W               IQ    DTS F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>162.155</Hsp_bit-score>
      <Hsp_score>409</Hsp_score>
      <Hsp_evalue>3.6322e-43</Hsp_evalue>
      <Hsp_query-from>494</Hsp_query-from>
      <Hsp_query-to>1351</Hsp_query-to>
      <Hsp_hit-from>82</Hsp_hit-from>
      <Hsp_hit-to>373</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>104</Hsp_identity>
      <Hsp_positive>155</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>305</Hsp_align-len>
      <Hsp_qseq>RVTSSDFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLVKGL----LCGRVDRLT--PDKLLCHPFFAGIDWNN-------------IQHSDDDTSNF</Hsp_qseq>
      <Hsp_hseq>KYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLL-RKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPD---VTYTLC-GTPDYIAPEVVST----KPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAE--LKFP--PFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQF</Hsp_hseq>
      <Hsp_midline>+ + SDF++   +  G    V ++R    G  YA+K L+K  ++    V    +ER +L+  S P++  +   FQD   +++V  Y  GG+L  LL R   +    + +FY AE+ LA + LH    ++RDLKPEN+L+D+ GHIK+ DFG A  +     V+  L  G+PDY+APEV+S+      Y    DWWS GV+ YEM+ G TPF    + KT  NI N +  ++FP  P    +  DL+K L    L  R+  L    + +  HP+F  + W               IQ    DTS F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>166.392</Hsp_bit-score>
      <Hsp_score>420</Hsp_score>
      <Hsp_evalue>1.59664e-42</Hsp_evalue>
      <Hsp_query-from>509</Hsp_query-from>
      <Hsp_query-to>1351</Hsp_query-to>
      <Hsp_hit-from>343</Hsp_hit-from>
      <Hsp_hit-to>629</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>106</Hsp_identity>
      <Hsp_positive>163</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>299</Hsp_align-len>
      <Hsp_qseq>DFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPS--EPAVSVEFVDLVKGLL----CGRVDRLTPDKLLCHPFFAGIDWNN------------IQHSDDDTSNF</Hsp_qseq>
      <Hsp_hseq>DFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHL-QHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFG-LCKLNMKDNDKTDTFCGTPEYLAPEIL---LGQG-YTKTVDWWTLGILLYEMMTGLPPYYD--ENVPVMYKKILQQPLLFPDGFDPAAK----DLLIGLLSRDPSRRLGVNGTDEIRNHPFFKDISWKKLLLKGYIPPYKPIVKSEIDTANF</Hsp_hseq>
      <Hsp_midline>DF++  V+ +G   +V  VR++ T  +YA+K L+K+ ++ +  V     ER VLAR   P++  L+++FQ  + LYLV  +  GG+L   L ++E +   +  RFY+AEL+ A  SLH++  ++RDLKPEN+L+D  GHI L DFG   KLN      +    G+P+Y+APE+L    G+G Y    DWW++G++ YEM+ G  P+ +      +   K  Q+ + FP   +PA      DL+ GLL      R+     D++  HPFF  I W              I  S+ DT+NF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YPR111W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:747306:749000:1 gene:YPR111W transcript:YPR111W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF20 description:Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006315]</Hit_def>
  <Hit_accession>YPR111W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>163.696</Hsp_bit-score>
      <Hsp_score>413</Hsp_score>
      <Hsp_evalue>2.67846e-42</Hsp_evalue>
      <Hsp_query-from>485</Hsp_query-from>
      <Hsp_query-to>1330</Hsp_query-to>
      <Hsp_hit-from>160</Hsp_hit-from>
      <Hsp_hit-to>480</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>105</Hsp_identity>
      <Hsp_positive>165</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>326</Hsp_align-len>
      <Hsp_qseq>QELRVTSSDFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSS---KLPE------------------------------------GSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFP----SEPAVSVEFVDLVKGLLCGRVDRL-TPDKLLCHPFFAGIDWNNIQHS</Hsp_qseq>
      <Hsp_hseq>RRLKPKHKDFQILTQVGQGGYGQVYLAKKKDSDEICALKILNKKLLFKLNETNHVLTERDILTTTRSDWLVKLLYAFQDPESLYLAMEFVPGGDFRTLLINTR-ILKSGHARFYISEMFCAVNALHELGYTHRDLKPENFLIDATGHIKLTDFGLAAGTVSNERIESMKIRLEEVKNLEFPAFTERSIEDRRKIYHNMRKTEINYANSMVGSPDYMALEVL---EGK-KYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYENLRYWKKTLRRPRTEDRRAAFSDRTWDLITRLIADPINRVRSFEQVRKMSYFAEINFETLRTS</Hsp_hseq>
      <Hsp_midline>+ L+    DF++   V +G + +V + +++ + ++ A+K+L K LL   +       ERD+L    S WL  L YAFQD ++LYL   + PGGD   LL      L     RFY++E+  A  +LH++GY HRDLKPEN L+D TGHIKL DFG AA   +N+ + S   +L E                                    GSPDY+A EVL    GK  Y    D+WS+G + +E + G TPF+   + +T  N++ ++K +R P       A S    DL+  L+   ++R+ + +++    +FA I++  ++ S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>165.622</Hsp_bit-score>
      <Hsp_score>418</Hsp_score>
      <Hsp_evalue>4.0342e-42</Hsp_evalue>
      <Hsp_query-from>476</Hsp_query-from>
      <Hsp_query-to>1333</Hsp_query-to>
      <Hsp_hit-from>312</Hsp_hit-from>
      <Hsp_hit-to>614</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>99</Hsp_identity>
      <Hsp_positive>165</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>309</Hsp_align-len>
      <Hsp_qseq>SELQELRVTSSDFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLL-GLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPE-----------------GSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLVKGLLCGRVDRLTPDK-----LLCHPFFAGIDWNNIQHSD</Hsp_qseq>
      <Hsp_hseq>NKFQDITVEPQSFEKIRLLGQGDVGKVYLVRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVI---RGNG-HTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNI--LTKDVKFPHDKEVSKNCKDLIKKLLNKNEAKRLGSKSGAADIKRHPFFKKVQWSFLRNQD</Hsp_hseq>
      <Hsp_midline>++ Q++ V    FE   ++ +G   +V +VRER T  ++A+KVL K  ++ R  +     E+++LA +  P++  L ++FQ +D LYL   Y  GG+    L  R    + E   +FY +E+V A + LH +G+++RDLKPEN+L+ ++GH+ L+DF  + +   +K  + K                    G+ +Y+APEV+    G G +    DWW++G++ YEM++G TPF    S +T SNI    K V+FP +  VS    DL+K LL     +    K     +  HPFF  + W+ +++ D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>162.925</Hsp_bit-score>
      <Hsp_score>411</Hsp_score>
      <Hsp_evalue>5.45737e-42</Hsp_evalue>
      <Hsp_query-from>485</Hsp_query-from>
      <Hsp_query-to>1324</Hsp_query-to>
      <Hsp_hit-from>168</Hsp_hit-from>
      <Hsp_hit-to>486</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>106</Hsp_identity>
      <Hsp_positive>162</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>324</Hsp_align-len>
      <Hsp_qseq>QELRVTSSDFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSS-----------KLPE----------------------------GSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSE----PAVSVEFVDLVKGLLCGRVDRL-TPDKLLCHPFFAGIDWNNIQ</Hsp_qseq>
      <Hsp_hseq>RRLKPKNRDFEMITQVGQGGYGQVYLARKKDTKEVCALKILNKKLLFKLNETKHVLTERDILTTTRSEWLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINTR-CLKSGHARFYISEMFCAVNALHDLGYTHRDLKPENFLIDAKGHIKLTDFGLAAGTISNERIESMKIRLEKIKDLEFPAFTEKSIEDRRKMYNQLREKEINYANSMVGSPDYMALEVL---EGK-KYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYDNLRRWKQTLRRPRQSDGRAAFSDRTWDLITRLIADPINRLRSFEHVKRMSYFADINFSTLR</Hsp_hseq>
      <Hsp_midline>+ L+  + DFE+   V +G + +V + R++ T +V A+K+L K LL   +       ERD+L    S WL  L YAFQD  +LYL   + PGGD   LL      L     RFY++E+  A  +LH +GY HRDLKPEN L+D  GHIKL DFG AA   +N+ + S           + P                             GSPDY+A EVL    GK  Y    D+WS+G + +E + G TPF+   + +T  N++ +++ +R P +     A S    DL+  L+   ++RL + + +    +FA I+++ ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>163.696</Hsp_bit-score>
      <Hsp_score>413</Hsp_score>
      <Hsp_evalue>1.24731e-41</Hsp_evalue>
      <Hsp_query-from>509</Hsp_query-from>
      <Hsp_query-to>1312</Hsp_query-to>
      <Hsp_hit-from>346</Hsp_hit-from>
      <Hsp_hit-to>607</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>99</Hsp_identity>
      <Hsp_positive>149</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>272</Hsp_align-len>
      <Hsp_qseq>DFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLVKGLL----CGRVDRLTPDKLLCHPFFAGIDW</Hsp_qseq>
      <Hsp_hseq>DFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQK-EGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFG-LCKLNMKDDDKTDTFCGTPEYLAPELLLGL----GYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKI--LQEPLVFPD--GFDRDAKDLLIGLLSRDPTRRLGYNGADEIRNHPFFSQLSW</Hsp_hseq>
      <Hsp_midline>DF++  V+ +G   +V  VR++ T  VYA+K ++KS ++ +  V     ER VLAR   P++  L+++FQ  + LY V  +  GG+L   L + E + D S  RFY AEL+ A  +LH++  V+RDLKPEN+L+D  GHI L DFG   KLN      +    G+P+Y+APE+L        Y    DWW++GV+ YEM+ G  P+ +    K    I   Q+ + FP       +  DL+ GLL      R+     D++  HPFF+ + W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>164.851</Hsp_bit-score>
      <Hsp_score>416</Hsp_score>
      <Hsp_evalue>1.75426e-41</Hsp_evalue>
      <Hsp_query-from>509</Hsp_query-from>
      <Hsp_query-to>1351</Hsp_query-to>
      <Hsp_hit-from>411</Hsp_hit-from>
      <Hsp_hit-to>701</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>117</Hsp_identity>
      <Hsp_positive>169</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>309</Hsp_align-len>
      <Hsp_qseq>DFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVL---ARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFG-SAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTP-FAEGISTKTISNIKNFQKF----VRFPSEPAVSVEFVDLVKGLL-------CGRVDRLTPDKLLCHPFFAGIDWNNIQH------------SDDDTSNF</Hsp_qseq>
      <Hsp_hseq>DFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQK-EGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFC----GTTEYLAPELLLDETG---YTKMVDFWSLGVLIFEMCCGWSPFFAE-------NNQKMYQKIAFGKVKFPRD-VLSQEGRSFVKGLLNRNPKHRLGAIDDGR--ELRAHPFFADIDWEALKQKKIPPPFKPHLVSETDTSNF</Hsp_hseq>
      <Hsp_midline>DFEV  ++ +G   +V  V+++ T  +YAMKVL K +++ ++ +A    ER++L   A  SSP++  L+++FQ   +LYLV  Y  GG+L   L + E +  E   +FY+AELVLA + LH    V+RDLKPEN+L+D  G+I L DFG S A L            G+ +Y+APE+L   +G   Y    D+WS+GV+ +EM  G +P FAE       +N K +QK     V+FP +  +S E    VKGLL        G +D     +L  HPFFA IDW  ++             S+ DTSNF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>162.54</Hsp_bit-score>
      <Hsp_score>410</Hsp_score>
      <Hsp_evalue>1.33526e-40</Hsp_evalue>
      <Hsp_query-from>476</Hsp_query-from>
      <Hsp_query-to>1312</Hsp_query-to>
      <Hsp_hit-from>484</Hsp_hit-from>
      <Hsp_hit-to>782</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>102</Hsp_identity>
      <Hsp_positive>163</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>309</Hsp_align-len>
      <Hsp_qseq>SELQELRVTSSDFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLL-GLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADF---------------GSA-AKLNANKMVSSKLPE----GSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLVKGLLCGRVDRLTPDKLLC---------HPFFAGIDW</Hsp_qseq>
      <Hsp_hseq>NKFQDIMVGPQSFEKIRLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVI---RGNG-HTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNI--LKNEVSFPNNNEISRTCKDLIKKLLTKNESK----RLGCKMGAADVKKHPFFKKVQW</Hsp_hseq>
      <Hsp_midline>++ Q++ V    FE   ++ +G   +V +VRE+ T  VYA+KVL K  ++ R+ +     E+++LA ++ P++  L ++FQ ED LYL   Y  GG+    L  R    + E   RFY +E+  A + LH +G+++RDLKPEN+L+ ++GHI L+DF               GSA + L   K+ S         G+ +Y+APEV+    G G +    DWW++G++ YEM++G TPF    + +T +NI   +  V FP+   +S    DL+K LL     +    +L C         HPFF  + W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>156.377</Hsp_bit-score>
      <Hsp_score>394</Hsp_score>
      <Hsp_evalue>1.6932e-38</Hsp_evalue>
      <Hsp_query-from>509</Hsp_query-from>
      <Hsp_query-to>1312</Hsp_query-to>
      <Hsp_hit-from>178</Hsp_hit-from>
      <Hsp_hit-to>448</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>101</Hsp_identity>
      <Hsp_positive>146</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>284</Hsp_align-len>
      <Hsp_qseq>DFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLAR-ASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPE-----------GSPDYVAPEVLS-SFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKF--VRFPSEPAVSVEFVDLVKGLLCGRVD-RLTPDKLLCHPFFAGIDW</Hsp_qseq>
      <Hsp_hseq>DFKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKY-GSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSK-PEYDLSTRSKSFVGTAEYVSPELLNDSFTDY-----RCDIWAFGCILFQMIAGKPPF------KATNEYLTFQKVMKVQYAFTPGFPLIIRDLVKKILVKNLDRRLTISQIKEHHFFKDLNF</Hsp_hseq>
      <Hsp_midline>DF+   V+  G +S V +     T   YA KVL K  L+ +  V     E+  L +  +SP +  L   FQDE +LY +  Y P GD L L+ +Y   LDE+  R+Y A+++ A   LH  G +HRD+KPEN+L+D    IKL DFG+A  LN      SK PE           G+ +YV+PE+L+ SF+        CD W+ G I ++M+ GK PF      K  +    FQK   V++   P   +   DLVK +L   +D RLT  ++  H FF  +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>154.066</Hsp_bit-score>
      <Hsp_score>388</Hsp_score>
      <Hsp_evalue>2.95728e-38</Hsp_evalue>
      <Hsp_query-from>509</Hsp_query-from>
      <Hsp_query-to>946</Hsp_query-to>
      <Hsp_hit-from>351</Hsp_hit-from>
      <Hsp_hit-to>495</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>146</Hsp_align-len>
      <Hsp_qseq>DFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFG</Hsp_qseq>
      <Hsp_hseq>DFHTVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQ-LFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFG</Hsp_hseq>
      <Hsp_midline>DF    V+ +G   EV++V+++ TG +YAMK L KS +  +D +A  + ERDVLA + SPW+  L Y+FQD   LYL+  + PGGDL+ +L R++    E + RFY+AE +LA +++H++G++HRD+KP+N+L+D  GHIKL+DFG</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>100.138</Hsp_bit-score>
      <Hsp_score>248</Hsp_score>
      <Hsp_evalue>2.41903e-21</Hsp_evalue>
      <Hsp_query-from>998</Hsp_query-from>
      <Hsp_query-to>1459</Hsp_query-to>
      <Hsp_hit-from>573</Hsp_hit-from>
      <Hsp_hit-to>746</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>178</Hsp_align-len>
      <Hsp_qseq>GSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLVKGLLCGRVDRL----TPDKLLCHPFFAGIDWNNIQH----------SDDDTSNFXX-------XXXXXXXXXXXXXQLRQPGFSG---NNLPFIGFSYSK</Hsp_qseq>
      <Hsp_hseq>GTPDYIAPEI---FLYQG-YGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHADQRLGRHGGADEIKSHPFFRGVDWNTIRQVEAPYIPKLSSITDTRFFPTDELENVPDSPAMAQAAKQREQMTKQGGSAPVKEDLPFIGYTYSR</Hsp_hseq>
      <Hsp_midline>G+PDY+APE+   F  +G YG ECDWWS+G I YE + G  PF      +T   I NF++ ++FP +  +S E  DL++ LL     RL      D++  HPFF G+DWN I+           S  DT  F                A     Q+ + G S     +LPFIG++YS+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>144.05</Hsp_bit-score>
      <Hsp_score>362</Hsp_score>
      <Hsp_evalue>4.28527e-35</Hsp_evalue>
      <Hsp_query-from>509</Hsp_query-from>
      <Hsp_query-to>1339</Hsp_query-to>
      <Hsp_hit-from>124</Hsp_hit-from>
      <Hsp_hit-to>405</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>97</Hsp_identity>
      <Hsp_positive>151</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>295</Hsp_align-len>
      <Hsp_qseq>DFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARAS-SPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSA------------AKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFV----DLVKGLLC-GRVDRLTPDKLLCHPFFAGIDWNNIQHSDDD</Hsp_qseq>
      <Hsp_hseq>DFKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQKLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKY-GSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLND----NYTDSRCDIWAFGCILYQMLAGKPPF------KAANEYLTFQKVMKI--QYAFTAGFPQIVKDLVKKLLVRDPNDRLTIKQIKAHLFFHEVNFEDGSVWDDN</Hsp_hseq>
      <Hsp_midline>DF+    +  G +S V +   R +G  YA+KVL K  L+ +  V     E+  L + + +  +  L + FQDE +LY +  Y P GD LGL+ +Y   L+E+  R+Y ++++ A  SLH +G +HRD+KPEN+L+D+   +KL DFG+A             K   +    SK   G+ +YV+PE+L+           CD W+ G I Y+M+ GK PF      K  +    FQK ++   + A +  F     DLVK LL     DRLT  ++  H FF  +++ +    DD+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>133.265</Hsp_bit-score>
      <Hsp_score>334</Hsp_score>
      <Hsp_evalue>1.49027e-32</Hsp_evalue>
      <Hsp_query-from>485</Hsp_query-from>
      <Hsp_query-to>1318</Hsp_query-to>
      <Hsp_hit-from>119</Hsp_hit-from>
      <Hsp_hit-to>420</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>96</Hsp_identity>
      <Hsp_positive>148</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>313</Hsp_align-len>
      <Hsp_qseq>QELRVTSSDFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEE--------------------------RDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPE---------GSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLVKGLLCGRVDRLTPDKLLCHPFFAGIDWNN</Hsp_qseq>
      <Hsp_hseq>NELSRNLHDFKPVRVLGQGAYGKVLLVKDVNTSKLYAMKQLRKAEILISQTATDSKREDEDKNDGNNNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEH-GTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEIL---LGK-AYSQNCDWYSLGCLLYDMLVGKPPYT-GSNHKVIIN-----KIQQNKQGPKIPFYLSEGMKDILNALLKKETAKRWNVDKYWAKTGANN</Hsp_hseq>
      <Hsp_midline> EL     DF+   V+ +G + +V +V++  T  +YAMK L+K+ +L        + E                          R +L+    P +  L Y+F D   LYL+  Y PGG+L   L  +   LDE+ V FY AE+  A + LH  G V+RDLKPEN L+++ GH+ L DFG + K   +  V  + PE         G+P+Y APE+L    GK +Y   CDW+S+G + Y+M+ GK P+  G + K I N     K  +    P +     + +K +L   + + T  +     ++A    NN</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>132.88</Hsp_bit-score>
      <Hsp_score>333</Hsp_score>
      <Hsp_evalue>2.26336e-31</Hsp_evalue>
      <Hsp_query-from>509</Hsp_query-from>
      <Hsp_query-to>1318</Hsp_query-to>
      <Hsp_hit-from>10</Hsp_hit-from>
      <Hsp_hit-to>300</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>89</Hsp_identity>
      <Hsp_positive>158</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>304</Hsp_align-len>
      <Hsp_qseq>DFEVRGVVSRGHHSEV-QVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERD---VLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNA------------------NKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVR--FPSEP---------AVSVEFVDLVKGLLCGRVD-RLTPDKLLCHPFFAGIDWNN</Hsp_qseq>
      <Hsp_hseq>DFIFKEELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKM-GTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFV--GTAEYVSPELL--LYNQCGYG--SDIWALGCMIYQFVQGQPPF------RGENELKTFEKIVALDYPWGPNNRINNSTSPINPLVINLVQKILVIEVNERISLEQIKRHPYFSKVDWND</Hsp_hseq>
      <Hsp_midline>DF  +  +  G +S V + + +++   +YA+KV  K  ++    V     E++   +LA+     +  L Y F DE+NLY V  + PGG+LL LL +     ++   R + A+L+ A + +H  G +HRDLKPENVL+DR G + + DFG+AA ++                   N+  +S +  G+ +YV+PE+L     +  YG   D W++G + Y+ V G+ PF      +  + +K F+K V   +P  P          ++   ++LV+ +L   V+ R++ +++  HP+F+ +DWN+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YFL033C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:69115:74427:-1 gene:YFL033C transcript:YFL033C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM15 description:Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase [Source:SGD;Acc:S000001861]</Hit_def>
  <Hit_accession>YFL033C</Hit_accession>
  <Hit_len>1770</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>124.79</Hsp_bit-score>
      <Hsp_score>312</Hsp_score>
      <Hsp_evalue>1.34635e-28</Hsp_evalue>
      <Hsp_query-from>281</Hsp_query-from>
      <Hsp_query-to>946</Hsp_query-to>
      <Hsp_hit-from>734</Hsp_hit-from>
      <Hsp_hit-to>938</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>119</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>PISSRFLRLNQLFQGKIAQPGQH-RYLATRDGLLDSLLVLFEECSDPGLMKHNHIANFVSKHAETVSELQELRVTSSDFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVL-ARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFG</Hsp_qseq>
      <Hsp_hseq>PISSPFT-----FSKDFLTPEQHPSNIARTDSINNAMLTSPNMPLSPLLLATNQT-------------VKSPTPSIKDYDILKPISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDKPYVARLFASFQNKDNLFLVMEYLPGGDLATLI-KMMGYLPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLIDNAGHVKLTDFG</Hsp_hseq>
      <Hsp_midline>PISS F      F      P QH   +A  D + +++L        P L+  N               ++    +  D+++   +S+G +  V + R++ TGD +A+KVL+KS ++ ++ V   + ER ++  ++  P++  L  +FQ++DNL+LV  Y PGGDL  L+ +    L +   + YL E+V+    +HQ G +H DLKPEN+L+D  GH+KL DFG</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>8.46766e-11</Hsp_evalue>
      <Hsp_query-from>998</Hsp_query-from>
      <Hsp_query-to>1321</Hsp_query-to>
      <Hsp_hit-from>1149</Hsp_hit-from>
      <Hsp_hit-to>1262</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>117</Hsp_align-len>
      <Hsp_qseq>GSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPF----AEGISTKTISNIKNFQKFVRFPSEPA-VSVEFVDLVKGLL----CGRVDRLTPDKLLCHPFFAGIDWNNI</Hsp_qseq>
      <Hsp_hseq>GTPDYLAPETIE---GKGEDNKQCDWWSVGCIFFELLLGYPPFHAETPDAVFKKILSGVIQWPEFKNEEEEREFLTPEAKDLIEKLLVVDPAKRLGAKGIQEIKDHPYFKNVDWDHV</Hsp_hseq>
      <Hsp_midline>G+PDY+APE +    GKG    +CDWWSVG I +E++ G  PF     + +  K +S +  + +F     E   ++ E  DL++ LL      R+      ++  HP+F  +DW+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>121.709</Hsp_bit-score>
      <Hsp_score>304</Hsp_score>
      <Hsp_evalue>8.54827e-28</Hsp_evalue>
      <Hsp_query-from>494</Hsp_query-from>
      <Hsp_query-to>1321</Hsp_query-to>
      <Hsp_hit-from>818</Hsp_hit-from>
      <Hsp_hit-to>1091</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>81</Hsp_identity>
      <Hsp_positive>149</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>292</Hsp_align-len>
      <Hsp_qseq>RVTSSDFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASS---PWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPE---GSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSV----EFVDLVKGLLCGRVDR------LTPDKLLCHPFFAGIDWNNI</Hsp_qseq>
      <Hsp_hseq>KVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHV--QNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYG----LCKDEMWYGNRTSTFCGTPEFMAPEILK----EQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAI--------LTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFFRNINFDDI</Hsp_hseq>
      <Hsp_midline>+V+  +F +  V+ +G+  +V + + + T  + A+KVL+K  ++   ++     E+ V   A+    P+LT+L  +FQ E+ +Y    +  GGDL+  +     +L     +FY AE++LA +  H  G ++RDLK EN+L+   GHIK+AD+G    L  ++M          G+P+++APE+L     +  Y    DWW+ GV+ Y+M+  ++PF+     +  + I           EP   +    E V + +GLL    ++         D+++  PFF  I++++I</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>7.80575e-06</Hsp_evalue>
      <Hsp_query-from>3802</Hsp_query-from>
      <Hsp_query-to>4068</Hsp_query-to>
      <Hsp_hit-from>475</Hsp_hit-from>
      <Hsp_hit-to>564</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>91</Hsp_align-len>
      <Hsp_qseq>RMHHNIPHRFSVGLNMRATK-CSVCLDTVHFGR-QASKCLECQVMCHPKCSVCLPATCGLPVEYATHFSEAMVRDKLNSPGLKLPEPPHSL</Hsp_qseq>
      <Hsp_hseq>KLNHRIPHRFLPTSN-RGTKWCCHCGYILPWGRHKVRKCSECGIMCHAQCAHLVPDFCGMSMEMANKILKTIQDTKRNQEKKKRTVPSAQL</Hsp_hseq>
      <Hsp_midline>+++H IPHRF    N R TK C  C   + +GR +  KC EC +MCH +C+  +P  CG+ +E A    + +   K N    K   P   L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>108.612</Hsp_bit-score>
      <Hsp_score>270</Hsp_score>
      <Hsp_evalue>1.18987e-24</Hsp_evalue>
      <Hsp_query-from>512</Hsp_query-from>
      <Hsp_query-to>1336</Hsp_query-to>
      <Hsp_hit-from>18</Hsp_hit-from>
      <Hsp_hit-to>285</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>135</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>282</Hsp_align-len>
      <Hsp_qseq>FEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRD-NVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGR-YEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLVKGLLCG-----RVDRLTPDKLLCHPFFAGIDWNNIQHSDD</Hsp_qseq>
      <Hsp_hseq>YSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVN---LEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRDTFV--GTPYWMAPEVVC--CEVDGYNEKADIWSLGITTYELLKGLPPLSKYDPMKVMTNLPK-----RKP--PKLQGPFSDAAKDFVAGCLVKTPADRPSAYNLLSFEFVKNITITNLKSDVD</Hsp_hseq>
      <Hsp_midline>+ ++  + RG+  +V    +R T ++ A+KV+    L H D ++ L  +E   LA   SP +T+      ++ ++++V  Y  GG    LL R Y + L E  V F + E+ L  + LH+   +HRD+K  N+L++  G +KL DFG +  + +     + +  G+P ++APEV+        Y  + D WS+G+  YE++ G  P ++    K ++N+       R P  P +   F D  K  + G       DR +   LL   F   I   N++   D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>110.923</Hsp_bit-score>
      <Hsp_score>276</Hsp_score>
      <Hsp_evalue>1.48413e-24</Hsp_evalue>
      <Hsp_query-from>539</Hsp_query-from>
      <Hsp_query-to>1297</Hsp_query-to>
      <Hsp_hit-from>28</Hsp_hit-from>
      <Hsp_hit-to>289</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>85</Hsp_identity>
      <Hsp_positive>131</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>271</Hsp_align-len>
      <Hsp_qseq>GHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNV------------AL---FEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLVKGLLCGRVD---RLTPDKLLCHPFF</Hsp_qseq>
      <Hsp_hseq>GSTGKVQLARNGSTGQEAAVKVISKAVF-NTGNVSGTSIVGSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFF-RQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALETEGKLLETSC--GSPHYAAPEIV---SGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILT--VDPERRIKTRDILKHPLL</Hsp_hseq>
      <Hsp_midline>G   +VQ+ R  +TG   A+KV+ K++  +  NV            AL    E E  ++   + P +  L   ++   +LYLV  Y   G+L  LL       +   +RF+  ++++     H +G VHRDLKPEN+L+D   +IK+ADFG AA     K++ +    GSP Y APE++   SG    G   D WS GVI + ++ G+ PF E         +K  +     PS+  +S E  DL++ +L   VD   R+    +L HP  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>106.301</Hsp_bit-score>
      <Hsp_score>264</Hsp_score>
      <Hsp_evalue>1.61093e-24</Hsp_evalue>
      <Hsp_query-from>509</Hsp_query-from>
      <Hsp_query-to>1297</Hsp_query-to>
      <Hsp_hit-from>103</Hsp_hit-from>
      <Hsp_hit-to>355</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>79</Hsp_identity>
      <Hsp_positive>131</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>267</Hsp_align-len>
      <Hsp_qseq>DFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSA---AKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLVKGLL-CGRVDRLTPDKLLCHPFF</Hsp_qseq>
      <Hsp_hseq>DFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLL-RLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTVC-----GTIDYLSPEMVES----REYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALD--IKMPSN--ISQDAQDLILKLLKYDPKDRMRLGDVKMHPWI</Hsp_hseq>
      <Hsp_midline>DFE+   + +G   +V  VR R+TG + A+KV++K  ++  +    F  E ++    + P LT     F DE  +YL+  Y   G++  LL R     ++ +   Y+ ++  A   +H+   +HRD+KPEN+L+     IKL DFG +      N  K V      G+ DY++PE++ S      Y    D W++GV+A+E++ G  PF E +   T   I      ++ PS   +S +  DL+  LL     DR+    +  HP+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>107.842</Hsp_bit-score>
      <Hsp_score>268</Hsp_score>
      <Hsp_evalue>6.43116e-24</Hsp_evalue>
      <Hsp_query-from>509</Hsp_query-from>
      <Hsp_query-to>1168</Hsp_query-to>
      <Hsp_hit-from>54</Hsp_hit-from>
      <Hsp_hit-to>266</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>220</Hsp_align-len>
      <Hsp_qseq>DFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKN</Hsp_qseq>
      <Hsp_hseq>NYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEY-AGNELFDYIVQ-RDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFLKTSC--GSPNYAAPEVI---SGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISN</Hsp_hseq>
      <Hsp_midline>++++   +  G   +V++     TG   A+K++ K +L   D     E E   L     P +  L    + +D + +V  Y  G +L   + +  D++ E   R +  +++ A +  H+   VHRDLKPEN+L+D   ++K+ADFG +  +     + +    GSP+Y APEV+   SGK   GPE D WS GVI Y M+  + PF +        NI N</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>104.375</Hsp_bit-score>
      <Hsp_score>259</Hsp_score>
      <Hsp_evalue>2.32144e-23</Hsp_evalue>
      <Hsp_query-from>404</Hsp_query-from>
      <Hsp_query-to>1300</Hsp_query-to>
      <Hsp_hit-from>15</Hsp_hit-from>
      <Hsp_hit-to>310</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>90</Hsp_identity>
      <Hsp_positive>149</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>310</Hsp_align-len>
      <Hsp_qseq>ECSDPGLMKHNHIANFVSKHAETVSELQELRVTSSDFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVAL--FEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLG-LLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVL-VDRTGH--IKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPF----AEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLV-KGLLCGRVDRLTPDKLLCHPFFA</Hsp_qseq>
      <Hsp_hseq>DVQDPERLNGHPVAKFINK----LSGQPESYVNRTNYIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKKAL-QGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSR--GKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYK-AAGSLGYVAPEVLT----QDGHGKPCDIWSIGVITYTLLCGYSPFIAESVEGFMEECTAS--RYPVTFHMPYWDNISIDVKRFILKALRLNPADRPTATELLDDPWIT</Hsp_hseq>
      <Hsp_midline>+  DP  +  + +A F++K    +S   E  V  +++     +  G    V+  R+ +T +  A+K+L K  L   +NV L    EE  +L + S P +   +  F+ +D  Y+V     GG+L   +L R   +  E      + +++ A + +H    VHRDLKPENVL VD++ +  + +ADFG A +L   + +  K   GS  YVAPEVL+    +  +G  CD WS+GVI Y ++ G +PF     EG   +  ++   +      P    +S++    + K L     DR T  +LL  P+  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>102.834</Hsp_bit-score>
      <Hsp_score>255</Hsp_score>
      <Hsp_evalue>5.78885e-23</Hsp_evalue>
      <Hsp_query-from>419</Hsp_query-from>
      <Hsp_query-to>1126</Hsp_query-to>
      <Hsp_hit-from>21</Hsp_hit-from>
      <Hsp_hit-to>239</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>125</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>240</Hsp_align-len>
      <Hsp_qseq>GLMKHNHIANFVSKHAETVSELQELRVTSSDFEVRGVVSRGHHSEVQVVRERATGDVYAMKVL-QKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVL-VDRTGHIKL--ADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPF</Hsp_qseq>
      <Hsp_hseq>GKMAHVQPASYVNKKKYVFGKT----LGAGTF---GVVRQAKNTE--------TGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRI-LVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYK-PAGSLGYVAPEVLT----QDGHGKPCDIWSIGVITYTLLCGYSAF</Hsp_hseq>
      <Hsp_midline>G M H   A++V+K      +     + +  F   GVV +  ++E        TG+  A+K+L +K+L  ++  +    +E D+L R   P +   +  F+ +D  Y++     GG+L   + +     +E  VR  L E++ A + +H    VHRDLKPEN+L +D++    L  ADFG A +L +++ +  K P GS  YVAPEVL+    +  +G  CD WS+GVI Y ++ G + F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>105.145</Hsp_bit-score>
      <Hsp_score>261</Hsp_score>
      <Hsp_evalue>9.40797e-23</Hsp_evalue>
      <Hsp_query-from>539</Hsp_query-from>
      <Hsp_query-to>1297</Hsp_query-to>
      <Hsp_hit-from>30</Hsp_hit-from>
      <Hsp_hit-to>285</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>79</Hsp_identity>
      <Hsp_positive>132</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>263</Hsp_align-len>
      <Hsp_qseq>GHHSEVQVVRERATGDVYAMKVLQKSLLLHR------DNVALFEEERDVLARA--SSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAA-KLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLV-KGLLCGRVDRLTPDKLLCHPFF</Hsp_qseq>
      <Hsp_hseq>GSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCF-RQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSC---GSPHYAAPEIVSGLPYEGF---ASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLL</Hsp_hseq>
      <Hsp_midline>G   +VQ+ +   TG   A+KV+ KS+  +       D+V  +  ER+++     S P +  L   ++  +NLYL+  Y   G+L  LL  +    +   +  +  ++++     H +G VHRDLKPEN+L+D   +IK+ADFG AA + +A+ + +S    GSP Y APE++S    +G      D WS GVI + ++ G+ PF E         +K  +     P++  +S +  DL+ K L+     R+    +L HP  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>102.834</Hsp_bit-score>
      <Hsp_score>255</Hsp_score>
      <Hsp_evalue>2.76623e-22</Hsp_evalue>
      <Hsp_query-from>578</Hsp_query-from>
      <Hsp_query-to>1303</Hsp_query-to>
      <Hsp_hit-from>103</Hsp_hit-from>
      <Hsp_hit-to>339</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>121</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>243</Hsp_align-len>
      <Hsp_qseq>TGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLVKGLLC-GRVDRLTPDKLLCHPFFAG</Hsp_qseq>
      <Hsp_hseq>SGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKR-RKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVL-ANESERKYTICGTPNYIAPEVLMGKHSGHSF--EVDIWSLGVMLYALLIGKPPF-QARDVNTIYERIKCRDF-SFPRDKPISDEGKILIRDILSLDPIERPSLTEIMDYVWFRG</Hsp_hseq>
      <Hsp_midline>+G+++A K + K+ +           E  +    S P +      F+D+ N+Y++    P G L+ LL R    L E  VRF+  ++  A + +H    +HRDLK  N+  D   ++K+ DFG AA L AN+        G+P+Y+APEVL       S+  E D WS+GV+ Y ++ GK PF +     TI      + F  FP +  +S E   L++ +L    ++R +  +++ + +F G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>98.5969</Hsp_bit-score>
      <Hsp_score>244</Hsp_score>
      <Hsp_evalue>6.51391e-21</Hsp_evalue>
      <Hsp_query-from>527</Hsp_query-from>
      <Hsp_query-to>1297</Hsp_query-to>
      <Hsp_hit-from>203</Hsp_hit-from>
      <Hsp_hit-to>466</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>128</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>271</Hsp_align-len>
      <Hsp_qseq>VVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGH--IKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVL---------SSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLVKGLLCGRVD---RLTPDKLLCHPFF</Hsp_qseq>
      <Hsp_hseq>VVGQGAFATVKKAIERTTGKTFAVKIISKRKVI--GNMDGVTRELEVLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAH-GAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFG-LAKVQGNGSFMKTFC-GTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGPLKDFRISEEARDFIDSLL--QVDPNNRSTAAKALNHPWI</Hsp_hseq>
      <Hsp_midline>VV +G  + V+   ER TG  +A+K++ K  ++   N+     E +VL + + P +  L+  ++D ++ Y+V  +  GGDL+  +  +   + E   R    +++ A + +H MG  HRDLKP+N+L+++     +K+ DFG  AK+  N         G+  YVAPEV+           +  +  Y    D WS+G + Y ++ G  PF+     +    I           +  +S E  D +  LL  +VD   R T  K L HP+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>96.6709</Hsp_bit-score>
      <Hsp_score>239</Hsp_score>
      <Hsp_evalue>3.61338e-20</Hsp_evalue>
      <Hsp_query-from>506</Hsp_query-from>
      <Hsp_query-to>1261</Hsp_query-to>
      <Hsp_hit-from>839</Hsp_hit-from>
      <Hsp_hit-to>1086</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>79</Hsp_identity>
      <Hsp_positive>125</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>262</Hsp_align-len>
      <Hsp_qseq>SDFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLH----RD-NVALFEEERDVLA---RASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLD--ESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLVKGLLCGRVDR</Hsp_qseq>
      <Hsp_hseq>SDFTILQVMGEGAYGKVNLCIHNREHYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKNSQENILKLLDFFEDDDYYYIETPVHGETGSIDLFDVIEFKKDMVEHEAKLVFKQVVASIKHLHDQGIVHRDIKDENVIVDSHGFVKLIDFGSAAYIKSGPF---DVFVGTMDYAAPEVLGGSSYKGK--PQ-DIWALGVLLYTIIYKENPYY------NIDEI--LEGELRFDKSEHVSEECISLIKRILTREVDK</Hsp_hseq>
      <Hsp_midline>SDF +  V+  G + +V +        +  +K++ K  +L     RD  +     E  ++A   + S   +  L   F+D+D  Y+  P H     + L    E + D  E   +    ++V + + LH  G VHRD+K ENV+VD  G +KL DFGSAA + +       +  G+ DY APEVL   S KG   P+ D W++GV+ Y ++Y + P+        I  I   +  +RF     VS E + L+K +L   VD+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>94.3597</Hsp_bit-score>
      <Hsp_score>233</Hsp_score>
      <Hsp_evalue>5.5777e-20</Hsp_evalue>
      <Hsp_query-from>647</Hsp_query-from>
      <Hsp_query-to>1300</Hsp_query-to>
      <Hsp_hit-from>208</Hsp_hit-from>
      <Hsp_hit-to>445</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>239</Hsp_align-len>
      <Hsp_qseq>FEEERDVLARASSPWLTHLQYAFQDEDN-LYLVRPYHPGGDLLGLLGRYE--DQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLV---DRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEV--------LSSFSGKGS-----YGPECDWWSVGVIAYEMVYGKTPF-AEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLVKGLL-CGRVDRLTPDKLLCHPFFA</Hsp_qseq>
      <Hsp_hseq>FDKEARILLRLDHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKERMHTVV-GTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGISPFYGDGSERSIIQNAKIGKLNFKLKQWDIVSDNAKSFVKDLLQTDVVKRLNSKQGLKHIWIA</Hsp_hseq>
      <Hsp_midline>F++E  +L R   P +  + + F D +N LY+ +   PGGDL   L + +    + E+     + +++ A   LH    VHRDLK +N+L+   +    I LADFG A  LN+NK     +  G+P+Y APEV          SFS   +     Y  +CD WS+GVI + M+ G +PF  +G     I N K  +   +      VS      VK LL    V RL   + L H + A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.5153</Hsp_bit-score>
      <Hsp_score>236</Hsp_score>
      <Hsp_evalue>7.26446e-20</Hsp_evalue>
      <Hsp_query-from>503</Hsp_query-from>
      <Hsp_query-to>1132</Hsp_query-to>
      <Hsp_hit-from>20</Hsp_hit-from>
      <Hsp_hit-to>222</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>213</Hsp_align-len>
      <Hsp_qseq>SSDFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQY---AFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAE</Hsp_qseq>
      <Hsp_hseq>SSLFKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLN----LDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLL--RPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTM-AGTPYWMAPEVI--MEGV-YYDTKVDIWSLGITTYEIATGNPPYCD</Hsp_hseq>
      <Hsp_midline>SS F+   V+ RG    V       TG VYA+KVL     L  D+  + + +R++   AS   ++++     ++  + +L+++  +  GG L  LL     ++DE  +   + EL++A + +H+   +HRD+K  NVL+   G++KL DFG AA++N   +    +  G+P ++APEV+    G   Y  + D WS+G+  YE+  G  P+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.9005</Hsp_bit-score>
      <Hsp_score>237</Hsp_score>
      <Hsp_evalue>7.96206e-20</Hsp_evalue>
      <Hsp_query-from>398</Hsp_query-from>
      <Hsp_query-to>1309</Hsp_query-to>
      <Hsp_hit-from>118</Hsp_hit-from>
      <Hsp_hit-to>373</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>82</Hsp_identity>
      <Hsp_positive>138</Hsp_positive>
      <Hsp_gaps>52</Hsp_gaps>
      <Hsp_align-len>306</Hsp_align-len>
      <Hsp_qseq>FEECSDPGLMKHNHIANFVSKHAETVSELQELRVTSSDFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTG-HIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLV-KGLLCGRVDRLTPDKLLCHPFFAGID</Hsp_qseq>
      <Hsp_hseq>FVHCSNNGTVPNSYSSSMVTSNVSSPS----------------IASREHSNHSQTNPYGIEREIVIMK-----LISHTNVMALFE-------------------VWENKSELYLVLEYVDGGELFDYLVS-KGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTSC--GSPHYASPEIV---MGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGK--YQMPSN--LSSEARDLISKILVIDPEKRITTQEILKHPLIKKYD</Hsp_hseq>
      <Hsp_midline>F  CS+ G + +++ ++ V+ +  + S                + SR H +  Q        ++  MK     L+ H + +ALFE                    ++++  LYLV  Y  GG+L   L   + +L E     Y  ++V      H     HRDLKPEN+L+D+    IK+ADFG AA    NK++ +    GSP Y +PE++    G+  +G   D WS G++ + ++ G  PF +    K +  +++ +   + PS   +S E  DL+ K L+     R+T  ++L HP     D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.5893</Hsp_bit-score>
      <Hsp_score>231</Hsp_score>
      <Hsp_evalue>1.31459e-19</Hsp_evalue>
      <Hsp_query-from>731</Hsp_query-from>
      <Hsp_query-to>1126</Hsp_query-to>
      <Hsp_hit-from>91</Hsp_hit-from>
      <Hsp_hit-to>222</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>135</Hsp_align-len>
      <Hsp_qseq>LYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLH-QMGYVHRDLKPENVLVDRTGHIKLADFGSAAKL--NANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPF</Hsp_qseq>
      <Hsp_hseq>MWIILEMADGGDLFDKI-EPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVL--YSEEGYYADRTDIWSIGILLFVLLTGQTPW</Hsp_hseq>
      <Hsp_midline>++++     GGDL   +   +  +D  + +FY  +LV A   LH + G  HRD+KPEN+L+D+ G++KLADFG A++       +  S    GSP Y+APEVL  +S +G Y    D WS+G++ + ++ G+TP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>91.6633</Hsp_bit-score>
      <Hsp_score>226</Hsp_score>
      <Hsp_evalue>4.67658e-19</Hsp_evalue>
      <Hsp_query-from>410</Hsp_query-from>
      <Hsp_query-to>1306</Hsp_query-to>
      <Hsp_hit-from>161</Hsp_hit-from>
      <Hsp_hit-to>483</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>87</Hsp_identity>
      <Hsp_positive>146</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>331</Hsp_align-len>
      <Hsp_qseq>SDPGLMKHNHIANFVSKHAETVSELQELRVTS-----SDFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAF-----QDEDNLYLVRPYHPGGDLLGLLGRYED-QLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTG-------------------HIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRF-PSEPAVSVEFVDLVKGLLCGRVD-RLTPDKLLCHPFFAGI</Hsp_qseq>
      <Hsp_hseq>NDDEVFKKPQISATSSQNATTSAAIRKLNKTRPVSFFDKYLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALF--KQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFG-LAKFTGEMQFTNTLC-GTPSYVAPEVLT----KKGYTSKVDLWSAGVILYVCLCGFPPFSDQLGPPSLKEQILQAKYAFYSPYWDKIDDSVLHLISNLLVLNPDERYNIDEALNHPWFNDI</Hsp_hseq>
      <Hsp_midline>+D  + K   I+   S++A T + +++L  T        + +   +  GH++ V+  + + TG   A+K+        +     F EE ++L R   P + +L  +F     + +   YLV      G+L   + R    + DES   F   +L+   + LH+   +HRD+KPEN+L++ T                     +K+ADFG  AK       ++ L  G+P YVAPEVL+    K  Y  + D WS GVI Y  + G  PF++ +   ++       K+  + P    +    + L+  LL    D R   D+ L HP+F  I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>92.0485</Hsp_bit-score>
      <Hsp_score>227</Hsp_score>
      <Hsp_evalue>1.13899e-18</Hsp_evalue>
      <Hsp_query-from>500</Hsp_query-from>
      <Hsp_query-to>1129</Hsp_query-to>
      <Hsp_hit-from>1030</Hsp_hit-from>
      <Hsp_hit-to>1253</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>228</Hsp_align-len>
      <Hsp_qseq>TSSDFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQ-KSLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLL--GRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANK-------------MVSSKLPE--GSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFA</Hsp_qseq>
      <Hsp_hseq>VSMRWQKRSFIGGGTFGQVYSAINLENGEILAVKEIKIHDTTTMKKIFPLIKEEMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEYCEGGSLASLLDHGRIEDEM---VTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGAD-DVWALGCVVLEMATGRRPWS</Hsp_hseq>
      <Hsp_midline> S  ++ R  +  G   +V        G++ A+K ++       +    L +EE  VL   + P +          D + +   Y  GG L  LL  GR ED++   + + Y  EL+     LHQ G VHRD+KPEN+L+D  G IK  DFG+A  +  ++             + +  L E  G+P Y+APE +S  + KG  G + D W++G +  EM  G+ P++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.1225</Hsp_bit-score>
      <Hsp_score>222</Hsp_score>
      <Hsp_evalue>3.88567e-18</Hsp_evalue>
      <Hsp_query-from>473</Hsp_query-from>
      <Hsp_query-to>1129</Hsp_query-to>
      <Hsp_hit-from>1253</Hsp_hit-from>
      <Hsp_hit-to>1501</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>254</Hsp_align-len>
      <Hsp_qseq>VSELQELRVTSSDFEVRGVVSRGHHSEVQVVRERATGDVYAMK--VLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLL--GRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKL--NANKMVSSKLPE-----------------------------GSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFA</Hsp_qseq>
      <Hsp_hseq>VSLASSISNVSMRWQKRNFIGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKI-FPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAALLEHGRIEDEM---VTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGAD-DVWSLGCVVLEMITGRRPWA</Hsp_hseq>
      <Hsp_midline>VS    +   S  ++ R  +  G    V    +   G++ A+K   +Q S  + +    L +EE  VL   + P +          D + +   Y  GG L  LL  GR ED++   + + Y  +L+     LH+ G VHRD+KPEN+L+D  G IK  DFG+A K+  N  ++ S    E                             G+P Y+APE ++  + KG  G + D WS+G +  EM+ G+ P+A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.9669</Hsp_bit-score>
      <Hsp_score>219</Hsp_score>
      <Hsp_evalue>9.6077e-18</Hsp_evalue>
      <Hsp_query-from>713</Hsp_query-from>
      <Hsp_query-to>1285</Hsp_query-to>
      <Hsp_hit-from>1171</Hsp_hit-from>
      <Hsp_hit-to>1355</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>199</Hsp_align-len>
      <Hsp_qseq>FQDEDNLYLVRPYHPGGDLLGL--LGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLVKGLL--C----GRVDRLTPDKLLC</Hsp_qseq>
      <Hsp_hseq>FEDDDYYYIETPVHGETGCIDLFDLIEFKTNMTEFEAKLIFKQVVAGIKHLHDQGIVHRDIKDENVIVDSKGFVKIIDFGSAAYVKSGPF---DVFVGTIDYAAPEVL---GGNPYEGQPQDIWAIGILLYTVVFKENPFY------NIDEI--LEGDLKFNNAEEVSEDCIELIKSILNRCVPKRPTIDDINNDKWLV</Hsp_hseq>
      <Hsp_midline>F+D+D  Y+  P H     + L  L  ++  + E   +    ++V   + LH  G VHRD+K ENV+VD  G +K+ DFGSAA + +       +  G+ DY APEVL    G    G   D W++G++ Y +V+ + PF        I  I   +  ++F +   VS + ++L+K +L  C      +D +  DK L </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YMR291W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:852630:854390:1 gene:YMR291W transcript:YMR291W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TDA1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000004905]</Hit_def>
  <Hit_accession>YMR291W</Hit_accession>
  <Hit_len>586</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.4261</Hsp_bit-score>
      <Hsp_score>215</Hsp_score>
      <Hsp_evalue>1.26887e-17</Hsp_evalue>
      <Hsp_query-from>539</Hsp_query-from>
      <Hsp_query-to>1351</Hsp_query-to>
      <Hsp_hit-from>48</Hsp_hit-from>
      <Hsp_hit-to>369</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>95</Hsp_identity>
      <Hsp_positive>139</Hsp_positive>
      <Hsp_gaps>67</Hsp_gaps>
      <Hsp_align-len>330</Hsp_align-len>
      <Hsp_qseq>GHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPW-------------------LTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQ-LD-ESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLV---------------------DRTGH-IKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKG-----------SYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFV--RFPSEPAVSVEFVDLVKGLLCGRVD---RLTPDKLLCHPFFAGIDWNNIQHSDDDTSNF</Hsp_qseq>
      <Hsp_hseq>GNFSVVKECMNIHTKDLYAMKLIKKQTV--KNKIQLIQREFDLLRSISEKIRDMEKKNEHSLDIFEGHHHILQLFDYFETADNIVLITQLCQKGDLYEKI--VENQCLDLETQVTSYCACLVSVLEFLHSQGIVHRDLKAENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLVLADFGLAAEYNTSKVNSLKEFVGTISYIAPEIVKC-KGVGEMTPDQVGKLDKYGCPVDIWALGVLTYFMAFGYTPFDCTTDDETLECISKCDYYVDEQMMHDPKYE-QFWNFVQ--CCFTIDPAVRRSAKNLKQHPFIKDYFATSNSLNTKDTPNF</Hsp_hseq>
      <Hsp_midline>G+ S V+      T D+YAMK+++K  +  ++ + L + E D+L   S                      +  L   F+  DN+ L+      GDL   +   E+Q LD E+ V  Y A LV   + LH  G VHRDLK ENVL                      D   H + LADFG AA+ N +K+ S K   G+  Y+APE++    G G            YG   D W++GV+ Y M +G TPF      +T+  I     +V  +   +P    +F + V+   C  +D   R +   L  HPF       +   +  DT NF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.0409</Hsp_bit-score>
      <Hsp_score>214</Hsp_score>
      <Hsp_evalue>3.16421e-17</Hsp_evalue>
      <Hsp_query-from>509</Hsp_query-from>
      <Hsp_query-to>1312</Hsp_query-to>
      <Hsp_hit-from>98</Hsp_hit-from>
      <Hsp_hit-to>383</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>137</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>296</Hsp_align-len>
      <Hsp_qseq>DFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQ---KSLLLHRDNVALFEEERDVLARASS-----------------------PWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLV-KGLLCGRVDRLTPDKLLCHPFFA-GIDW</Hsp_qseq>
      <Hsp_hseq>DWEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESEILERQKRLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQH-GSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYRKQLHTFC--GSLYFAAPELLKA---QPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGK--VDYPSH--LSIEVISLLTRMIVVDPLRRATLKNVVEHPWMNRGYDF</Hsp_hseq>
      <Hsp_midline>D+E    V  G   +V++V+ R T ++  +K++    K+ L  + ++   + E ++L R                          P +  L       ++ Y++  Y  GG LL  + ++   L E   R +   +  A Q LH    VHRDLK EN+++  +G IK+ DFG +   +  K + +    GS  + APE+L +   +   GPE D WS G++ Y +V GK PF +  S+     IK  +  V +PS   +S+E + L+ + ++   + R T   ++ HP+   G D+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YDL028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:400997:403291:-1 gene:YDL028C transcript:YDL028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MPS1 description:Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]</Hit_def>
  <Hit_accession>YDL028C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.6557</Hsp_bit-score>
      <Hsp_score>213</Hsp_score>
      <Hsp_evalue>3.47677e-17</Hsp_evalue>
      <Hsp_query-from>800</Hsp_query-from>
      <Hsp_query-to>1297</Hsp_query-to>
      <Hsp_hit-from>535</Hsp_hit-from>
      <Hsp_hit-to>716</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>183</Hsp_align-len>
      <Hsp_qseq>LDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKM-VSSKLPEGSPDYVAPEVLSSFS-----------GKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPA----VSVEFVDLVKGLLCGRVD-RLTPDKLLCHPFF</Hsp_qseq>
      <Hsp_hseq>LDFNFVRFYTKEMLLCIKVVHDAGIVHSDLKPANFVLVK-GILKIIDFGIANAVPEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYGKPPYGSFQGQNRLLAIMNPDVKIPFPEHTSNNEKIPKSAIELMKACLYRNPDKRWTVDKVLSSTFL</Hsp_hseq>
      <Hsp_midline>LD + VRFY  E++L  + +H  G VH DLKP N ++ + G +K+ DFG A  +  + + +  +   G+P+Y+APE L + +            K   G   D WS G I Y+M+YGK P+        +  I N    + FP   +    +    ++L+K  L    D R T DK+L   F </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.1149</Hsp_bit-score>
      <Hsp_score>209</Hsp_score>
      <Hsp_evalue>9.3143e-17</Hsp_evalue>
      <Hsp_query-from>584</Hsp_query-from>
      <Hsp_query-to>1132</Hsp_query-to>
      <Hsp_hit-from>480</Hsp_hit-from>
      <Hsp_hit-to>659</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>185</Hsp_align-len>
      <Hsp_qseq>DVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNA-NKMVSSKLP-EGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAE</Hsp_qseq>
      <Hsp_hseq>DVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNY-GPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVK----QTATTAKADIWSTGCVVIEMFTGKHPFPD</Hsp_hseq>
      <Hsp_midline>DV A+   + +  +HR  V   + E ++L       +     A Q+  NL +   Y PGG +  +L  Y    +ES++  +  ++++    LH+   +HRD+K  N+L+D  G +K+ DFG + KL+  NK  + +   +GS  +++PEV+     + +   + D WS G +  EM  GK PF +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.8037</Hsp_bit-score>
      <Hsp_score>203</Hsp_score>
      <Hsp_evalue>3.36166e-16</Hsp_evalue>
      <Hsp_query-from>506</Hsp_query-from>
      <Hsp_query-to>1195</Hsp_query-to>
      <Hsp_hit-from>48</Hsp_hit-from>
      <Hsp_hit-to>297</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>120</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>255</Hsp_align-len>
      <Hsp_qseq>SDFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQK-------SLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDN--LYLVRPYHPGGDL-------LGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFG---SAAKLNAN------KMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPS</Hsp_qseq>
      <Hsp_hseq>NNFEILATLGNGQYGKVKLARDLGTGALVAIKILNRFEKRSGYSLQLKVENPRV-NQEIEVMKRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVAMSTATGSTNIQSSHEQLLKSR-ALGTPAFFAPE-LCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPFNANSGLELFDSIIN--KPLEFPS</Hsp_hseq>
      <Hsp_midline>++FE+   +  G + +V++ R+  TG + A+K+L +       SL L  +N  +  +E +V+ R     +  L     D ++  +YLV  Y   G +       + +       L     R  + ++V   + LH  G  HRD+KP N+L+   G +K++DFG   S A  + N      +++ S+   G+P + APE L S   + S     D WS+GV  Y +++GK PF      +   +I N  K + FPS</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.5741</Hsp_bit-score>
      <Hsp_score>205</Hsp_score>
      <Hsp_evalue>3.87705e-16</Hsp_evalue>
      <Hsp_query-from>494</Hsp_query-from>
      <Hsp_query-to>1246</Hsp_query-to>
      <Hsp_hit-from>114</Hsp_hit-from>
      <Hsp_hit-to>380</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>126</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>277</Hsp_align-len>
      <Hsp_qseq>RVTSSDFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSL--LLHRDNV-ALFEEERDVLARASS-----------------------PWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLVKGLLC</Hsp_qseq>
      <Hsp_hseq>RKSLGDWEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPPPKNEQDVLERQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQH-GSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIYDSRKQLHTFC--GSLYFAAPELLKA---NPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKIK--QGKVEYPQH--LSIEVISLLSKMLV</Hsp_hseq>
      <Hsp_midline>R +  D+E    V  G   +V++ + R T +V A+K++ ++    LH++ +    + E+DVL R                          P +  L       ++ Y++  Y  GG LL  + ++   + E   R +   +  A   LH    VHRDLK EN+++  +  IK+ DFG +   ++ K + +    GS  + APE+L +       GPE D WS GV+ + +V GK PF +  S+     IK  Q  V +P    +S+E + L+  +L </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.6481</Hsp_bit-score>
      <Hsp_score>200</Hsp_score>
      <Hsp_evalue>6.699e-16</Hsp_evalue>
      <Hsp_query-from>737</Hsp_query-from>
      <Hsp_query-to>1126</Hsp_query-to>
      <Hsp_hit-from>305</Hsp_hit-from>
      <Hsp_hit-to>445</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>146</Hsp_align-len>
      <Hsp_qseq>LVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVD----------------RTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPF</Hsp_qseq>
      <Hsp_hseq>MIMSYCPAGDLLAAVMARNGRLEAWLIQRIFTEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLCKKIENNEMCTARC--GSEDYVSPEILMGVPYDGHLS---DTWALGVILYSLFEDRLPF</Hsp_hseq>
      <Hsp_midline>++  Y P GDLL  +     +L+  +++    E+VLA + LH+   +HRDLK EN+L+                 +   I+LADFG   K+  N+M +++   GS DYV+PE+L      G      D W++GVI Y +   + PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.6481</Hsp_bit-score>
      <Hsp_score>200</Hsp_score>
      <Hsp_evalue>1.17318e-15</Hsp_evalue>
      <Hsp_query-from>728</Hsp_query-from>
      <Hsp_query-to>1126</Hsp_query-to>
      <Hsp_hit-from>689</Hsp_hit-from>
      <Hsp_hit-to>814</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>133</Hsp_align-len>
      <Hsp_qseq>NLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPF</Hsp_qseq>
      <Hsp_hseq>DLWVIMEYMEGGSLTDVVTHC--ILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTM-VGTPYWMAPEVVS----RKEYGPKVDIWSLGIMIIEMIEGEPPY</Hsp_hseq>
      <Hsp_midline>+L+++  Y  GG L  ++      L E  +     E +   + LH  G +HRD+K +N+L+   G IKL DFG  A++N   +  + +  G+P ++APEV+S    +  YGP+ D WS+G++  EM+ G+ P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.2629</Hsp_bit-score>
      <Hsp_score>199</Hsp_score>
      <Hsp_evalue>1.86957e-15</Hsp_evalue>
      <Hsp_query-from>692</Hsp_query-from>
      <Hsp_query-to>1294</Hsp_query-to>
      <Hsp_hit-from>1238</Hsp_hit-from>
      <Hsp_hit-to>1439</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>211</Hsp_align-len>
      <Hsp_qseq>LTHLQY-AFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLVKGL------LCGRVD---RLTPDKLLCHPF</Hsp_qseq>
      <Hsp_hseq>LNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQG---YSAKVDIWSLGCIVLEMFAGKRPWSN------LEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANELLSHPF</Hsp_hseq>
      <Hsp_midline>L  +QY  F++++N+Y +   +  G  +G L R   + DE +++    +++     LH  G +HRD+K +N+L+D+ G  K++DFG + K       S     G+  ++APE++ +  G   Y  + D WS+G I  EM  GK P++       +  +    K  +  S P +  + + L+  +       C  ++   R T ++LL HPF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.4925</Hsp_bit-score>
      <Hsp_score>197</Hsp_score>
      <Hsp_evalue>3.0228e-15</Hsp_evalue>
      <Hsp_query-from>470</Hsp_query-from>
      <Hsp_query-to>1243</Hsp_query-to>
      <Hsp_hit-from>10</Hsp_hit-from>
      <Hsp_hit-to>306</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>55</Hsp_gaps>
      <Hsp_align-len>305</Hsp_align-len>
      <Hsp_qseq>TVSELQELRVTSSDFEVRGVVSRGHHSEVQVVRERATGDV---YAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDE-----------------------SMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVD---------RTGH------------IKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLVKGLL</Hsp_qseq>
      <Hsp_hseq>TTSVNHNLMASAGNYTAEKEIGKG--SFATVYRGHLTSDKSQHVAIKEVSRAKLKNKKLLENLEIEIAILKKIKHPHIVGLIDCERTSTDFYLIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLC--GSPLYMAPEILNY----QKYNAKADLWSVGTVVFEMCCGTPPFRASNHLELFKKIKRANDVITFPSYCNIEPELKELICSLL</Hsp_hseq>
      <Hsp_midline>T S    L  ++ ++     + +G  S   V R   T D     A+K + ++ L ++  +   E E  +L +   P +  L    +   + YL+  Y   GDL  LL R ++ ++                        + V  YL +L  A + L     VHRD+KP+N+L+          ++ H            +K+ADFG A  L    +  +    GSP Y+APE+L+       Y  + D WSVG + +EM  G  PF      +    IK     + FPS   +  E  +L+  LL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.0258</Hsp_bit-score>
      <Hsp_score>188</Hsp_score>
      <Hsp_evalue>1.87221e-14</Hsp_evalue>
      <Hsp_query-from>524</Hsp_query-from>
      <Hsp_query-to>1303</Hsp_query-to>
      <Hsp_hit-from>218</Hsp_hit-from>
      <Hsp_hit-to>483</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>122</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>280</Hsp_align-len>
      <Hsp_qseq>GVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDE--DNLYLVRPYHPGG-------DLLGLLGRYEDQLDESMVRFYLAELVLATQS-LHQMGYVHRDLKPENVLVDRTGHIKLADFG-SAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFP----SEPAVSVEFVDLVKGLL--CGRVD---RLTPDKLLCHPFFAG</Hsp_qseq>
      <Hsp_hseq>GILGEGAGGSVAKCRLKNGKKVFALKTINTMNTDPEYQKQIFRELQ-FNKSFKSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISER-----VIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFGVSGEAVNSLAMTFT----GTSFYMAPERIQG----QPYSVTCDVWSLGLTLLEVAGGRFPFESDKITQNVAPIELLTMILTFSPQLKDEPELDISWSKTFRSFIDYCLKKDARERPSPRQMLKHPWIVG</Hsp_hseq>
      <Hsp_midline>G++  G    V   R +    V+A+K +            +F E +       S ++      F DE   ++Y+   Y  G        +LL   GR  ++     V   +AE VL   S LH+   +HRD+KP+N+L++  G IKL DFG S   +N+  M  +    G+  Y+APE +        Y   CD WS+G+   E+  G+ PF     T+ ++ I+     + F      EP + + +    +  +  C + D   R +P ++L HP+  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.411</Hsp_bit-score>
      <Hsp_score>189</Hsp_score>
      <Hsp_evalue>2.01514e-14</Hsp_evalue>
      <Hsp_query-from>494</Hsp_query-from>
      <Hsp_query-to>1126</Hsp_query-to>
      <Hsp_hit-from>354</Hsp_hit-from>
      <Hsp_hit-to>564</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>216</Hsp_align-len>
      <Hsp_qseq>RVTSSDFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYED--QLDESMVRFYLAELVLATQSL-HQMGYVHRDLKPENVLVDRT-GHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFS-GKGSYGPECDWWSVGVIAYEMVYGKTPF</Hsp_qseq>
      <Hsp_hseq>RITLDELEFLDELGHGNYGNVSKVLHKPTNVIMATKEVRLELDEAKFRQILMELE--VLHKCNSPYIVDFYGAFFIEGAVYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSANQGTVKLCDFGVSGNLVASL---AKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPY</Hsp_hseq>
      <Hsp_midline>R+T  + E    +  G++  V  V  + T  + A K ++  L   +    L E E  VL + +SP++     AF  E  +Y+   Y  GG L  +     +   +DE  + F    ++   + L  Q   +HRD+KP N+L     G +KL DFG +  L A+    +K   G   Y+APE + S +  + +Y  + D WS+G+   EM  G+ P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.0258</Hsp_bit-score>
      <Hsp_score>188</Hsp_score>
      <Hsp_evalue>2.18984e-14</Hsp_evalue>
      <Hsp_query-from>719</Hsp_query-from>
      <Hsp_query-to>1126</Hsp_query-to>
      <Hsp_hit-from>444</Hsp_hit-from>
      <Hsp_hit-to>582</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>144</Hsp_align-len>
      <Hsp_qseq>DEDNLYLVRPYHPGGDLLGLL--------GRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPF</Hsp_qseq>
      <Hsp_hseq>DDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMV-GTPYWMAPEIVNQ---KG-YDEKVDVWSLGIMLIEMIEGEPPY</Hsp_hseq>
      <Hsp_midline>D++ L+++  Y  GG L  +L        G +   L+E+ + + + E     + LH    +HRD+K +N+L++  G +K+ DFG   +L   +   + +  G+P ++APE+++    KG Y  + D WS+G++  EM+ G+ P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.411</Hsp_bit-score>
      <Hsp_score>189</Hsp_score>
      <Hsp_evalue>2.83769e-14</Hsp_evalue>
      <Hsp_query-from>473</Hsp_query-from>
      <Hsp_query-to>1126</Hsp_query-to>
      <Hsp_hit-from>12</Hsp_hit-from>
      <Hsp_hit-to>218</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>226</Hsp_align-len>
      <Hsp_qseq>VSELQELRVTSSDFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYA--------FQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPF</Hsp_qseq>
      <Hsp_hseq>LTPIQRASEKSVQYHLKQVIGRGSYGVVYKAINKHTDQVVAIK----EVVYEND-----EELNDIMAEIS--LLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSALTLA----GTLNWMAPEIL----GNRGASTLSDIWSLGATVVEMLTKNPPY</Hsp_hseq>
      <Hsp_midline>++ +Q     S  + ++ V+ RG +  V     + T  V A+K     ++   D     EE  D++A  S   L +L +          +    LY++  Y   G L  L+ R    L E+  + Y+ + +L  + LH  G +HRD+K  N+L+     +KLADFG +  +N++ +  +    G+ +++APE+L    G        D WS+G    EM+    P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.6406</Hsp_bit-score>
      <Hsp_score>187</Hsp_score>
      <Hsp_evalue>4.23662e-14</Hsp_evalue>
      <Hsp_query-from>656</Hsp_query-from>
      <Hsp_query-to>1192</Hsp_query-to>
      <Hsp_hit-from>100</Hsp_hit-from>
      <Hsp_hit-to>279</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>185</Hsp_align-len>
      <Hsp_qseq>ERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAK-LNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFV-----RFP</Hsp_qseq>
      <Hsp_hseq>EINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLF-AQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMKTSC--GSPCYAAPELV--VSTKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARLYKYITQTPLKFP</Hsp_hseq>
      <Hsp_midline>E + L   + P + +L+   Q+   + +V  +  GG+    + R     + S  R + A+L+     +H  G VHRDLK EN+L+D+  ++ + DFG   +    N+++ +    GSP Y APE++   S K     + D WS GVI Y M+ G  P+ +     T  +I    K++     +FP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YIL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:287790:288908:-1 gene:YIL035C transcript:YIL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA1 description:Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000001297]</Hit_def>
  <Hit_accession>YIL035C</Hit_accession>
  <Hit_len>372</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.3294</Hsp_bit-score>
      <Hsp_score>181</Hsp_score>
      <Hsp_evalue>5.44302e-14</Hsp_evalue>
      <Hsp_query-from>497</Hsp_query-from>
      <Hsp_query-to>1306</Hsp_query-to>
      <Hsp_hit-from>35</Hsp_hit-from>
      <Hsp_hit-to>366</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>85</Hsp_identity>
      <Hsp_positive>137</Hsp_positive>
      <Hsp_gaps>80</Hsp_gaps>
      <Hsp_align-len>341</Hsp_align-len>
      <Hsp_qseq>VTSSDFEVRGVVSRGHHSEV--QVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPY-----HPGG-------DLL--------GLLGRYEDQLDESM---------VRFYLAELVLATQSLHQMGYVHRDLKPENVLVD-RTGHIKLADFGSA----AKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTK-------TISNIKNFQK------------------FVRFPSEPAV---------SVEFVDLVKGLL-CGRVDRLTPDKLLCHPFFAGI</Hsp_qseq>
      <Hsp_hseq>TNTKDYEIENKVGRGKYSEVFQGVKLDSKVKIVIKMLKPVKKKKIKREIKILTDLSNEKVPPTTLPFQKDQYYTNQKEDVLKFIRPYIFDQPHNGHANIIHLFDIIKDPISKTPALVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKG------PELLVDYR---MYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLLKYEITLPREFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWFAPI</Hsp_hseq>
      <Hsp_midline>  + D+E+   V RG +SEV   V  +     V  M    K   + R+   L +   + +   + P+     Y  Q ED L  +RPY     H G        D++         L+  Y D +D  +         +RFY+ EL+ A    H MG +HRD+KP NV++D +   ++L D+G A      +  N  V+S+  +G      PE+L  +     Y    D WS G +   M++ + PF  G S          +    +F+K                  ++R P    +         + E +DL+  LL     +RLT  + + HP+FA I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.0998</Hsp_bit-score>
      <Hsp_score>183</Hsp_score>
      <Hsp_evalue>1.05849e-13</Hsp_evalue>
      <Hsp_query-from>701</Hsp_query-from>
      <Hsp_query-to>1297</Hsp_query-to>
      <Hsp_hit-from>626</Hsp_hit-from>
      <Hsp_hit-to>825</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>207</Hsp_align-len>
      <Hsp_qseq>LQYAFQDEDNLYLVRPYHPGGDLLGLL------GRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNI-KNFQKFVRFPSEPAVSVEFVDLVKGLLCGRVD-RLTPDKLLCHPFF</Hsp_qseq>
      <Hsp_hseq>LEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATM-VGTPYWMAPEVVK----QREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATNGTPKLKHPE--SLSLEIKRFLSVCLCVDVRYRASTEELLHHGFF</Hsp_hseq>
      <Hsp_midline>L+   + +D+L++V  +  GG L  ++            L E  + + + E     + LH    +HRD+K +NVL+D    +K+ DFG  A+L   +   + +  G+P ++APEV+     +  Y  + D WS+G++  EM+ G+ P+      K +  I  N    ++ P   ++S+E    +   LC  V  R + ++LL H FF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.3294</Hsp_bit-score>
      <Hsp_score>181</Hsp_score>
      <Hsp_evalue>1.3329e-13</Hsp_evalue>
      <Hsp_query-from>668</Hsp_query-from>
      <Hsp_query-to>1132</Hsp_query-to>
      <Hsp_hit-from>188</Hsp_hit-from>
      <Hsp_hit-to>358</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>180</Hsp_align-len>
      <Hsp_qseq>LARASSPWLTHLQYAFQDEDNLY-LVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVD------------------------RTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAE</Hsp_qseq>
      <Hsp_hseq>LVSKNNPHCTKF-IAFQESANYYYLVTELVTGGEIFDRIVQLT-CFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLRNN---TAKTPCGTIEYVASEVFTS----KRYSMKVDMWSIGCVLFTLLCGYPPFYE</Hsp_hseq>
      <Hsp_midline>L   ++P  T    AFQ+  N Y LV     GG++   + +      E + R  + ++ +A + +H MG VHRD+KPEN+L +                          G +KL DFG A KL  N   ++K P G+ +YVA EV +S      Y  + D WS+G + + ++ G  PF E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.9442</Hsp_bit-score>
      <Hsp_score>180</Hsp_score>
      <Hsp_evalue>2.56741e-13</Hsp_evalue>
      <Hsp_query-from>686</Hsp_query-from>
      <Hsp_query-to>1297</Hsp_query-to>
      <Hsp_hit-from>92</Hsp_hit-from>
      <Hsp_hit-to>287</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>211</Hsp_align-len>
      <Hsp_qseq>PWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSY-GPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFV-----DLVKGLLCGRV-DRLTPDKLLCHPFF</Hsp_qseq>
      <Hsp_hseq>PYITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELF-AQISGAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTRECMTKTTLETVC--GTTVYMAPELIE----RRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVN--------EEPKYDAKVIPDDARDLISRLLAKNPGERPSLSQVLRHPFL</Hsp_hseq>
      <Hsp_midline>P++T L      E  +++   Y PG +L   L              + A++  A    H M  VHRDLK EN+L+D+ G+ KL DFG   +      + +    G+  Y+APE++     + +Y G + D WS+GVI Y ++ G  PF +    KT   I N         EP    + +     DL+  LL     +R +  ++L HPF </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>3.19588e-13</Hsp_evalue>
      <Hsp_query-from>656</Hsp_query-from>
      <Hsp_query-to>1306</Hsp_query-to>
      <Hsp_hit-from>86</Hsp_hit-from>
      <Hsp_hit-to>332</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>114</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>256</Hsp_align-len>
      <Hsp_qseq>ERDVLARASSPWLTHLQYAFQ------DEDNLY---LVRPYHPGGDLLGLLGRYED---QLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVL-VDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKT-------------ISNIKN------------FQKFVR-FPSEPAVSVEFVDLVKGLLCGRVDRLTPDKLLCHPFFAGI</Hsp_qseq>
      <Hsp_hseq>ELEILQNIRHPNLVTLEFFFESHCTTKDGGHLYQKNFVMEYIPQ-TLSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGIAKVCDFGSAQRLDDNTELKTYF--CSRFYRAPELLLN---SKDYTTQIDIWSLGCIIGEMIKGQ-PLFKGDSANSQLEEIAKLLGRFPKSSIKNSQELQDSLNDQKFKKFMHWFPSIEFFDVEF--LLKVLTYDATERCDARQLMAHEFFDAL</Hsp_hseq>
      <Hsp_midline>E ++L     P L  L++ F+      D  +LY    V  Y P   L   +  Y D   ++    ++ Y  +++ A  +LH M   H DLKP N+L +  +G  K+ DFGSA +L+ N  + +     S  Y APE+L +      Y  + D WS+G I  EM+ G+ P  +G S  +              S+IKN            F+KF+  FPS     VEF  L+K L     +R    +L+ H FF  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.7886</Hsp_bit-score>
      <Hsp_score>177</Hsp_score>
      <Hsp_evalue>3.64169e-13</Hsp_evalue>
      <Hsp_query-from>473</Hsp_query-from>
      <Hsp_query-to>1135</Hsp_query-to>
      <Hsp_hit-from>171</Hsp_hit-from>
      <Hsp_hit-to>383</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>223</Hsp_align-len>
      <Hsp_qseq>VSELQELRVTSSDFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFE-EERDVLARASSPWLTHL-QYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEG</Hsp_qseq>
      <Hsp_hseq>VSVLTQQRSTSVYLRIMQV-GEGTYGKVYKAKNTNTEKLVALKKLR--LQGEREGFPITSIREIKLLQSFDHPNVSTIKEIMVESQKTVYMIFEY-ADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKMNSRADYTNRVI--TLWYRPPELL---LGTTNYGTEVDMWGCGCLLVEL-FNKTAIFQG</Hsp_hseq>
      <Hsp_midline>VS L + R TS    +  V   G + +V   +   T  + A+K L+  L   R+   +    E  +L     P ++ + +   + +  +Y++  Y    DL GLL   E Q+  S  +    +L+L  + LH    +HRD+K  N+L+D  G++K+ DFG A K+N+    ++++   +  Y  PE+L    G  +YG E D W  G +  E+ + KT   +G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>6.24501e-13</Hsp_evalue>
      <Hsp_query-from>815</Hsp_query-from>
      <Hsp_query-to>1126</Hsp_query-to>
      <Hsp_hit-from>141</Hsp_hit-from>
      <Hsp_hit-to>240</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>105</Hsp_align-len>
      <Hsp_qseq>VRFYLAELVLATQSLHQMGYVHRDLKPENVLVD-RTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPF</Hsp_qseq>
      <Hsp_hseq>IRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSISYI--CSRFYRAPELI---IGCTQYTTQIDIWGLGCVMGEMLIGKAIF</Hsp_hseq>
      <Hsp_midline>+R Y  ++      LH +G  HRD+KP NVLVD  TG +K+ DFGSA KL  N+   S +   S  Y APE++    G   Y  + D W +G +  EM+ GK  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.7886</Hsp_bit-score>
      <Hsp_score>177</Hsp_score>
      <Hsp_evalue>6.92043e-13</Hsp_evalue>
      <Hsp_query-from>833</Hsp_query-from>
      <Hsp_query-to>1138</Hsp_query-to>
      <Hsp_hit-from>818</Hsp_hit-from>
      <Hsp_hit-to>926</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>116</Hsp_align-len>
      <Hsp_qseq>ELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAK----LNANKMVSSKLPEGSPD----------YVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGI</Hsp_qseq>
      <Hsp_hseq>QILEALSYIHSQGIIHRDLKPMNIFIDESRNVKIGDFGLAKNVHRSLDILKLDSQNLP-GSSDNLTSAIGTAMYVATEVL---DGTGHYNEKIDMYSLGIIFFEMIY---PFSTGM</Hsp_hseq>
      <Hsp_midline>+++ A   +H  G +HRDLKP N+ +D + ++K+ DFG A      L+  K+ S  LP GS D          YVA EVL    G G Y  + D +S+G+I +EM+Y   PF+ G+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YDL025C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:405344:407206:-1 gene:YDL025C transcript:YDL025C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RTK1 description:Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002183]</Hit_def>
  <Hit_accession>YDL025C</Hit_accession>
  <Hit_len>620</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>7.66043e-13</Hsp_evalue>
      <Hsp_query-from>539</Hsp_query-from>
      <Hsp_query-to>1270</Hsp_query-to>
      <Hsp_hit-from>311</Hsp_hit-from>
      <Hsp_hit-to>545</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>69</Hsp_gaps>
      <Hsp_align-len>274</Hsp_align-len>
      <Hsp_qseq>GHHSEVQVVRERATGDVYAMKVLQKSLL--------------------------LHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLN---ANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPE-CDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLVKGLLCGRVDRLTP</Hsp_qseq>
      <Hsp_hseq>GASGSVSVV-ERTDGKLFACKMFRKPHLNNEGTNQSQLANYSKKVTTEFCIGSTLHHENIV---ETLDMLTEGDT-YLLVMEYAPYDFFNLVM-----------------SNLMTQDEVNCYFKQLCHGVNYLHSMGLAHRDLKLDNCVVTKDGILKLIDFGSAVVFQYPYEDTIVKSHGIVGSDPYLAPELLK----QTSYDPRVADVWSIAIIFYCMVLKRFPWK--------APKKSFNSFRLFTEEPE---DEDDIVRG--PNKILRLLP</Hsp_hseq>
      <Hsp_midline>G    V VV ER  G ++A K+ +K  L                          LH +N+    E  D+L    + +L  ++YA  D  NL +                  + + +  V  Y  +L      LH MG  HRDLK +N +V + G +KL DFGSA        + +V S    GS  Y+APE+L     + SY P   D WS+ +I Y MV  + P+         +  K+F  F  F  EP    +  D+V+G    ++ RL P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>1.31045e-12</Hsp_evalue>
      <Hsp_query-from>593</Hsp_query-from>
      <Hsp_query-to>1192</Hsp_query-to>
      <Hsp_hit-from>78</Hsp_hit-from>
      <Hsp_hit-to>279</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>208</Hsp_align-len>
      <Hsp_qseq>AMKVLQKSLLL--HRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKL-NANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFV-----RFP</Hsp_qseq>
      <Hsp_hseq>AIKLIKRDSISNDYRKEVKIYREI-NALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLF-SQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVNEFCSRNELMKTSC--GSPCYAAPELV--ISAEPYEARKADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGRLYNYINSTPLKFP</Hsp_hseq>
      <Hsp_midline>A+K++++  +   +R  V ++ E  + L   S P +  L+   Q+   + +V  Y  GG+    + +     + +  R + ++L+     +H  G VHRDLK EN+L+D+  ++ + DFG   +  + N+++ +    GSP Y APE++   S +     + D WS GVI Y ++ G  P+ +  +    S+I     ++     +FP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>2.10521e-12</Hsp_evalue>
      <Hsp_query-from>530</Hsp_query-from>
      <Hsp_query-to>1258</Hsp_query-to>
      <Hsp_hit-from>8</Hsp_hit-from>
      <Hsp_hit-to>262</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>270</Hsp_align-len>
      <Hsp_qseq>VSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASS----PWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQ-------LDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGP----------------ECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLVKGLLCGRVD</Hsp_qseq>
      <Hsp_hseq>IQSGTFSTVYKAWSTTHNRYVALKITPK----YKTSEANMKNEYDVMKILSSCNPHPNICSMLDFYTDDSYYIMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQIDMQKIIKQLCSAISFAHSLGIAHRDIKPENILLTINGDIKLADWGHAIQ----SPKSNDFQIGTDNYRAPE---TFSGRVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFGDCLFRVSKS-KKVQHLKNFDEFEK---DPFAFIYRKYVVPRLSCGYND</Hsp_hseq>
      <Hsp_midline>+  G  S V            A+K+  K    ++ + A  + E DV+   SS    P +  +   + D+    +V  Y   GDL   L   + Q       L +  ++  + +L  A    H +G  HRD+KPEN+L+   G IKLAD+G A +       S+    G+ +Y APE   +FSG+ S                   + D+WS+G   + +++G   F    S K + ++KNF +F +   +P   +    +V  L CG  D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>3.81204e-12</Hsp_evalue>
      <Hsp_query-from>512</Hsp_query-from>
      <Hsp_query-to>1303</Hsp_query-to>
      <Hsp_hit-from>221</Hsp_hit-from>
      <Hsp_hit-to>490</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>128</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>286</Hsp_align-len>
      <Hsp_qseq>FEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARAS--SPWLTHLQYAFQDEDN--LYLVRPYHPGGDLLGLLGRYEDQLDES-----MVRFYLAELVLATQS-LHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFV-------RFPSEPAVSVEFVDLVKGLL--CGRVD---RLTPDKLLCHPFFAG</Hsp_qseq>
      <Hsp_hseq>IETLGILGEGAGGSVSKCKLKNGSKIFALKVINT---LNTDPEYQKQIFRELQFNRSFQSEYIVRYYGMFTDDENSSIYIAMEYMGGRSLDAI---YKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVSGEA-VNSLATTF--TGTSFYMAPERIQG----QPYSVTSDVWSLGLTILEVANGKFPCS---SEKMAANIAPFELLMWILTFTPELKDEPESNIIWSPSFKSFIDYCLKKDSRERPSPRQMINHPWIKG</Hsp_hseq>
      <Hsp_midline> E  G++  G    V   + +    ++A+KV+     L+ D     +  R++    S  S ++      F D++N  +Y+   Y  G  L  +   Y++ L+        V   +AE VL   S LH+   +HRD+KP+N+L++  G +KL DFG + +   N + ++    G+  Y+APE +        Y    D WS+G+   E+  GK P +   S K  +NI  F+  +           EP  ++ +    K  +  C + D   R +P +++ HP+  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.5514</Hsp_bit-score>
      <Hsp_score>166</Hsp_score>
      <Hsp_evalue>8.78458e-12</Hsp_evalue>
      <Hsp_query-from>713</Hsp_query-from>
      <Hsp_query-to>1126</Hsp_query-to>
      <Hsp_hit-from>256</Hsp_hit-from>
      <Hsp_hit-to>420</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>43</Hsp_gaps>
      <Hsp_align-len>173</Hsp_align-len>
      <Hsp_qseq>FQDEDNLY-LVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVL---VDRTGHI-------------------------------KLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPF</Hsp_qseq>
      <Hsp_hseq>FQETDSYYYIIQELLTGGEIFGEIVRLT-YFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSK---NTKTPCGTVGYTAPEVVKD----EHYSMKVDMWGIGCVLYTMLCGFPPF</Hsp_hseq>
      <Hsp_midline>FQ+ D+ Y +++    GG++ G + R      E + R  + +L LA + +H +G VHRD+KPEN+L   ++ T  I                               KLADFG + ++ +    ++K P G+  Y APEV+        Y  + D W +G + Y M+ G  PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>3.12308e-11</Hsp_evalue>
      <Hsp_query-from>800</Hsp_query-from>
      <Hsp_query-to>1126</Hsp_query-to>
      <Hsp_hit-from>116</Hsp_hit-from>
      <Hsp_hit-to>217</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>112</Hsp_align-len>
      <Hsp_qseq>LDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKM---VSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPF</Hsp_qseq>
      <Hsp_hseq>LEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFG-LARIQDPQMTGYVSTRY------YRAPEIMLTWQ---KYDVEVDIWSAGCIFAEMIEGKPLF</Hsp_hseq>
      <Hsp_midline>L++  V+++L +++   + +H  G +HRDLKP N+L++    +K+ DFG  A++   +M   VS++       Y APE++ ++     Y  E D WS G I  EM+ GK  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>4.03017e-11</Hsp_evalue>
      <Hsp_query-from>512</Hsp_query-from>
      <Hsp_query-to>1126</Hsp_query-to>
      <Hsp_hit-from>39</Hsp_hit-from>
      <Hsp_hit-to>240</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>216</Hsp_align-len>
      <Hsp_qseq>FEVRGVVSRGHHSEVQVVRERATGDVYAMK-VLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAF-----QDEDNLYLVRPYHPGGDLLGLLGRYEDQ---LDESMVRFYLAELVLATQSLHQMGYV-HRDLKPENVLVD-RTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPF</Hsp_qseq>
      <Hsp_hseq>FPTTEVVGHGSFGVVFATVIQETNEKVAIKKVLQDKRFKNR--------ELEIMKMLSHINIIDLKYFFYERDSQDEIYLNLILEYMPQS-LYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVSYI--CSRYYRAPELI---FGATNYTNQIDIWSSGCVMAELLLGQPMF</Hsp_hseq>
      <Hsp_midline>F    VV  G    V     + T +  A+K VLQ     +R        E +++   S   +  L+Y F     QDE  L L+  Y P   L   L  +  Q   +    +++Y+ +L  +   LH    V HRD+KP+N+LVD  T  +KL DFGSA +L   +   S +   S  Y APE++    G  +Y  + D WS G +  E++ G+  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YOR267C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:822588:824867:-1 gene:YOR267C transcript:YOR267C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRK1 description:Protein kinase; implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005793]</Hit_def>
  <Hit_accession>YOR267C</Hit_accession>
  <Hit_len>759</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>6.03204e-11</Hsp_evalue>
      <Hsp_query-from>815</Hsp_query-from>
      <Hsp_query-to>1126</Hsp_query-to>
      <Hsp_hit-from>317</Hsp_hit-from>
      <Hsp_hit-to>421</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>108</Hsp_align-len>
      <Hsp_qseq>VRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLN---ANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPEC-DWWSVGVIAYEMVYGKTPF</Hsp_qseq>
      <Hsp_hseq>INCCLKQLTEGVKYLHSMGLAHRDLKLDNCVMTSQGILKLIDFGSAVVFRYPFEDGVTMAHGIVGSDPYLAPEVITS---TKSYDPQCVDIWSIGIIYCCMVLKRFPW</Hsp_hseq>
      <Hsp_midline>+   L +L    + LH MG  HRDLK +N ++   G +KL DFGSA        + +  +    GS  Y+APEV++S     SY P+C D WS+G+I   MV  + P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YOR061W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:441534:442553:1 gene:YOR061W transcript:YOR061W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA2 description:Alpha&apos; catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000005587]</Hit_def>
  <Hit_accession>YOR061W</Hit_accession>
  <Hit_len>339</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>8.70961e-11</Hsp_evalue>
      <Hsp_query-from>815</Hsp_query-from>
      <Hsp_query-to>1144</Hsp_query-to>
      <Hsp_hit-from>144</Hsp_hit-from>
      <Hsp_hit-to>249</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>115</Hsp_align-len>
      <Hsp_qseq>VRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGH-IKLADFGSA----AKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGIST</Hsp_qseq>
      <Hsp_hseq>IQYYFTQLLIALDYCHSMGIMHRDVKPQNVMIDPTERKLRLIDWGLAEFYHPGVDYNVRVASRYHKG------PELLVNLN---QYDYSLDLWSVGCMLAAIVFKKEPFFKGSSN</Hsp_hseq>
      <Hsp_midline>+++Y  +L++A    H MG +HRD+KP+NV++D T   ++L D+G A      ++ N  V+S+  +G      PE+L + +    Y    D WSVG +   +V+ K PF +G S </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>8.79464e-11</Hsp_evalue>
      <Hsp_query-from>779</Hsp_query-from>
      <Hsp_query-to>1126</Hsp_query-to>
      <Hsp_hit-from>98</Hsp_hit-from>
      <Hsp_hit-to>209</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>118</Hsp_align-len>
      <Hsp_qseq>LGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFG--SAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPF</Hsp_qseq>
      <Hsp_hseq>VGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVV---TLWYRAPDVL---MGSRTYSTSIDIWSCGCILAEMITGKPLF</Hsp_hseq>
      <Hsp_midline>+G     L+ ++V+++  +L+      H+   +HRDLKP+N+L+++ G +KL DFG   A  +  N   S  +   +  Y AP+VL    G  +Y    D WS G I  EM+ GK  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YDL079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:312951:314748:-1 gene:YDL079C transcript:YDL079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRK1 description:Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication [Source:SGD;Acc:S000002237]</Hit_def>
  <Hit_accession>YDL079C</Hit_accession>
  <Hit_len>501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>2.06984e-10</Hsp_evalue>
      <Hsp_query-from>656</Hsp_query-from>
      <Hsp_query-to>1129</Hsp_query-to>
      <Hsp_hit-from>205</Hsp_hit-from>
      <Hsp_hit-to>366</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>168</Hsp_align-len>
      <Hsp_qseq>ERDVLARASSPWLTHLQYAF-----QDEDNLYLVRPYHPGGDLLGLLGRYED---QLDESMVRFYLAELVLATQSLHQMGYV-HRDLKPENVLVDRTG-HIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFA</Hsp_qseq>
      <Hsp_hseq>ELETMKMLCHPNTVGLQYYFYEKDEEDEVYLNLVLDYMPQS-LYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYI--CSRYYRAPELM---FGATNYSNQVDVWSSACVIAELLLGKPLFS</Hsp_hseq>
      <Hsp_midline>E + +     P    LQY F     +DE  L LV  Y P   L   L  + +   Q+    ++FY  +L  A   LH +  + HRD+KP+N+LVD T    K+ DFGSA  L  ++   S +   S  Y APE++    G  +Y  + D WS   +  E++ GK  F+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YKL168C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:131288:133462:-1 gene:YKL168C transcript:YKL168C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KKQ8 description:Putative serine/threonine protein kinase with unknown cellular role; KKQ8 has a paralog, HAL5, that arose from the whole genome duplication [Source:SGD;Acc:S000001651]</Hit_def>
  <Hit_accession>YKL168C</Hit_accession>
  <Hit_len>724</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>3.74022e-10</Hsp_evalue>
      <Hsp_query-from>713</Hsp_query-from>
      <Hsp_query-to>1114</Hsp_query-to>
      <Hsp_hit-from>503</Hsp_hit-from>
      <Hsp_hit-to>640</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>141</Hsp_align-len>
      <Hsp_qseq>FQDEDNLYLVRPYHPGGDLLGLL---GRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNA---NKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPE-CDWWSVGVIAYEMVYG</Hsp_qseq>
      <Hsp_hseq>LEDSSSFIEVMEFCPAGDLYGMLVGKSKLKGRLHPLEADCFMKQLLHGVKFMHDHGIAHCDLKPENILFYPHGLLKICDFGTSSVFQTAWERRVHAQKGIIGSEPYVAPE---EFVDGEYYDPRLIDCWSCGVVYITMILG</Hsp_hseq>
      <Hsp_midline> +D  +   V  + P GDL G+L    + + +L       ++ +L+   + +H  G  H DLKPEN+L    G +K+ DFG+++        ++ + K   GS  YVAPE    F     Y P   D WS GV+   M+ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>71</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>4.39479e-10</Hsp_evalue>
      <Hsp_query-from>713</Hsp_query-from>
      <Hsp_query-to>1117</Hsp_query-to>
      <Hsp_hit-from>392</Hsp_hit-from>
      <Hsp_hit-to>526</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>141</Hsp_align-len>
      <Hsp_qseq>FQDEDNLYL-VRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLN----ANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPE-CDWWSVGVIAYEMVYGK</Hsp_qseq>
      <Hsp_hseq>FQDAKGEYCEVMEYCAGGDLFTLV-VAAGKLEYMEADCFFKQLIRGVVYMHEMGVCHRDLKPENLLLTHDGVLKITDFGNSECFKMAWEKNIHLSGGVCGSSP-YIAPEEYI----KEEFDPRPVDIWACGVIYMAMRTGR</Hsp_hseq>
      <Hsp_midline>FQD    Y  V  Y  GGDL  L+     +L+      +  +L+     +H+MG  HRDLKPEN+L+   G +K+ DFG++         N  +S  +   SP Y+APE       K  + P   D W+ GVI   M  G+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>72</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>6.14237e-10</Hsp_evalue>
      <Hsp_query-from>800</Hsp_query-from>
      <Hsp_query-to>1126</Hsp_query-to>
      <Hsp_hit-from>115</Hsp_hit-from>
      <Hsp_hit-to>226</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>115</Hsp_align-len>
      <Hsp_qseq>LDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYV------APEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPF</Hsp_qseq>
      <Hsp_hseq>LSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQ---EYTTAMDIWSCGCILAEMVSGKPLF</Hsp_hseq>
      <Hsp_midline>L +  V+++  +++ A +S+H    +HRD+KP N+L++    +K+ DFG A  L ++      L     +YV      APE++ +F     Y    D WS G I  EMV GK  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>73</Hit_num>
  <Hit_id>YNL020C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:595623:597539:-1 gene:YNL020C transcript:YNL020C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ARK1 description:Serine/threonine protein kinase; involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis; ARK1 has a paralog, PRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004965]</Hit_def>
  <Hit_accession>YNL020C</Hit_accession>
  <Hit_len>638</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>6.65989e-10</Hsp_evalue>
      <Hsp_query-from>731</Hsp_query-from>
      <Hsp_query-to>1246</Hsp_query-to>
      <Hsp_hit-from>105</Hsp_hit-from>
      <Hsp_hit-to>280</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>183</Hsp_align-len>
      <Hsp_qseq>LYLVRPYHPGGDLLGLLG-RYEDQLDESMVRFYLAELVLATQSLH--QMGYVHRDLKPENVLVDRTGHIKLADFGSAAKL-----NANKMVSSK---LPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLVKGLLC</Hsp_qseq>
      <Hsp_hseq>VFVLMEYCERGGLIDFMNTRLQNRLHEFEILQIMSQVTQGVAAMHALQPPLIHRDIKIENVLISANNEYKLCDFGSVCGIIRPPRNSQELSYVQQDILKNTTAQYRSPEMIDTFRGL-PIDEKSDIWALGIFLYKLCYYTTPFEKGGDLAILSG-----KF-EFPLYPNYSEQLKGLIRDILV</Hsp_hseq>
      <Hsp_midline>++++  Y   G L+  +  R +++L E  +   ++++     ++H  Q   +HRD+K ENVL+      KL DFGS   +     N+ ++   +   L   +  Y +PE++ +F G      + D W++G+  Y++ Y  TPF +G     +S      KF  FP  P  S +   L++ +L </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>74</Hit_num>
  <Hit_id>YDL214C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:74446:76545:-1 gene:YDL214C transcript:YDL214C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR2 description:Serine/threonine protein kinase; inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance; PRR2 has a paralog, NPR1, that arose from the whole genome duplication [Source:SGD;Acc:S000002373]</Hit_def>
  <Hit_accession>YDL214C</Hit_accession>
  <Hit_len>699</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>9.10096e-10</Hsp_evalue>
      <Hsp_query-from>764</Hsp_query-from>
      <Hsp_query-to>1231</Hsp_query-to>
      <Hsp_hit-from>446</Hsp_hit-from>
      <Hsp_hit-to>590</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>DLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLN---ANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPEC-DWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLV</Hsp_qseq>
      <Hsp_hseq>DLFSLVMSEKMHYEEICCLF--KQLINGVKYLHDIGLSHRDLKLDNCVVTRRGILKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFYF----NEYDPRALDVWSVGIIFFCMITRRFPWK-------YPKVKDVQ-FKAFCSGRGVS-SFKDLV</Hsp_hseq>
      <Hsp_midline>DL  L+   +   +E    F   +L+   + LH +G  HRDLK +N +V R G +KL DFG+++  +   +++M+ +    GS  Y++PEV         Y P   D WSVG+I + M+  + P+           +K+ Q F  F S   VS  F DLV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>75</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>1.08269e-09</Hsp_evalue>
      <Hsp_query-from>863</Hsp_query-from>
      <Hsp_query-to>1231</Hsp_query-to>
      <Hsp_hit-from>324</Hsp_hit-from>
      <Hsp_hit-to>443</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>129</Hsp_align-len>
      <Hsp_qseq>QMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKN-FQKFV-----RFPSEPAVSVEFVDLV</Hsp_qseq>
      <Hsp_hseq>QYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKL-INSIADTFV--GTSTYMSPERIQG----NVYSIKGDVWSLGLMIIELVTGEFPL--GGHNDTPDGILDLLQRIVNEPSPRLPKDRIYSKEMTDFV</Hsp_hseq>
      <Hsp_midline>Q   +HRD+KP NVL++  G IKL DFG + KL  N +  + +  G+  Y++PE +        Y  + D WS+G++  E+V G+ P   G    T   I +  Q+ V     R P +   S E  D V</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>76</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>1.20106e-09</Hsp_evalue>
      <Hsp_query-from>770</Hsp_query-from>
      <Hsp_query-to>1135</Hsp_query-to>
      <Hsp_hit-from>115</Hsp_hit-from>
      <Hsp_hit-to>235</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>129</Hsp_align-len>
      <Hsp_qseq>LGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEG---SPDYVAPEVLSSFSGKGSYGPEC----DWWSVGVIAYEMVYGKTPFAEG</Hsp_qseq>
      <Hsp_hseq>LSQIIRSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQ-------ECTKAVDIWSTGCILAELL-GRKPMFEG</Hsp_hseq>
      <Hsp_midline>L  + R E +L+++  + ++ +++ A + +H    +H DLKP+N+LV+    +K+ +FG +   + N  V+    +G   S  Y APE+L ++        EC    D WS G I  E++ G+ P  EG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>77</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>1.20997e-09</Hsp_evalue>
      <Hsp_query-from>797</Hsp_query-from>
      <Hsp_query-to>1135</Hsp_query-to>
      <Hsp_hit-from>137</Hsp_hit-from>
      <Hsp_hit-to>252</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>120</Hsp_align-len>
      <Hsp_qseq>QLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNAN--KMVSSKLPE-----GSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEG</Hsp_qseq>
      <Hsp_hseq>QLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLS---NQPYSKSVDIWAVGCILAEF-YARKPVFMG</Hsp_hseq>
      <Hsp_midline>QL E  ++++L +++   + +H    +HRDLKP N+L    G +K+ DFG A  ++A   K  S+  P       +  Y APE+L S      Y    D W+VG I  E  Y + P   G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>78</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.5362</Hsp_bit-score>
      <Hsp_score>140</Hsp_score>
      <Hsp_evalue>4.08135e-09</Hsp_evalue>
      <Hsp_query-from>530</Hsp_query-from>
      <Hsp_query-to>1135</Hsp_query-to>
      <Hsp_hit-from>13</Hsp_hit-from>
      <Hsp_hit-to>207</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>203</Hsp_align-len>
      <Hsp_qseq>VSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNA-NKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEG</Hsp_qseq>
      <Hsp_hseq>VGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVK-YLQEMQHPNVIELIDIFMAYDNLNLVLEFLPT-DLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNV--VTRWYRAPELL---FGAKHYTSAIDIWSVGVIFAELML-RIPYLPG</Hsp_hseq>
      <Hsp_midline>V  G ++ V +  + +TG   A+K ++ S      +++   E +  L     P +  L   F   DNL LV  + P  DL  ++         + ++ ++   +      H+   +HRDLKP N+L    G IK+ADFG A  + A +++++S +   +  Y APE+L    G   Y    D WSVGVI  E++  + P+  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>79</Hit_num>
  <Hit_id>YPL026C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:500675:502183:-1 gene:YPL026C transcript:YPL026C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKS1 description:Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway; SKS1 has a paralog, VHS1, that arose from the whole genome duplication [Source:SGD;Acc:S000005947]</Hit_def>
  <Hit_accession>YPL026C</Hit_accession>
  <Hit_len>502</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>4.25166e-09</Hsp_evalue>
      <Hsp_query-from>812</Hsp_query-from>
      <Hsp_query-to>1135</Hsp_query-to>
      <Hsp_hit-from>162</Hsp_hit-from>
      <Hsp_hit-to>278</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>120</Hsp_align-len>
      <Hsp_qseq>MVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPE-VLSSF--SGKGSYGPEC---------DWWSVGVIAYEMVYGKTPFAEG</Hsp_qseq>
      <Hsp_hseq>LIKKVFLQLCSALDHCHRLGIYHCDIKPENVLLDRNDNAYLCDFGLSTK---SKYLAPNVCVGSSYYMAPERILYCLNTTTNGIHVDECCSSLPTDTGDIWSLGIILINLTCIRNPWLKA</Hsp_hseq>
      <Hsp_midline>+++    +L  A    H++G  H D+KPENVL+DR  +  L DFG + K   +K ++  +  GS  Y+APE +L     +  G +  EC         D WS+G+I   +   + P+ + </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>80</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>5.54471e-09</Hsp_evalue>
      <Hsp_query-from>698</Hsp_query-from>
      <Hsp_query-to>1147</Hsp_query-to>
      <Hsp_hit-from>233</Hsp_hit-from>
      <Hsp_hit-to>371</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>159</Hsp_align-len>
      <Hsp_qseq>HLQYAFQDEDNLYLVRPY-HPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLN--------ANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTK</Hsp_qseq>
      <Hsp_hseq>HMVYEYAEHDLLQIIHFHSHPEKRMI----------PPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDGCVKIGDLGLARKFHNMLQTLYTGDKVVVTIW------YRAPELL---LGARHYTPAVDLWSVGCIFAELI-GLQPIFKGEEAK</Hsp_hseq>
      <Hsp_midline>H+ Y + + D L ++  + HP   ++             MVR  + +L+     LHQ   +HRDLKP N++V   G +K+ D G A K +         +K+V +        Y APE+L    G   Y P  D WSVG I  E++ G  P  +G   K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>81</Hit_num>
  <Hit_id>YJL165C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:106894:109461:-1 gene:YJL165C transcript:YJL165C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HAL5 description:Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters; HAL5 has a paralog, KKQ8, that arose from the whole genome duplication [Source:SGD;Acc:S000003701]</Hit_def>
  <Hit_accession>YJL165C</Hit_accession>
  <Hit_len>855</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>5.5603e-09</Hsp_evalue>
      <Hsp_query-from>824</Hsp_query-from>
      <Hsp_query-to>1282</Hsp_query-to>
      <Hsp_hit-from>668</Hsp_hit-from>
      <Hsp_hit-to>832</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>168</Hsp_align-len>
      <Hsp_qseq>YLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNA--NKMVSSKLPE-GSPDYVAPEVLSSFSGKGSYGPE-CDWWSVGVIAYEMVYGK------TPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEF-----VDLVKGLLCGRVDRLTPDKLL</Hsp_qseq>
      <Hsp_hseq>FMKQLLNGVQYMHDHGIAHCDLKPENILFQPNGLLKICDFGTSSVFQTAWEKHVHFQSGAMGSEPYVAPE---EFIRDAEYDPRLVDCWSCGIVYCTMVMGQYLWKIAIPEKDSLFKSFLSEIKDDGQFYLFEELRHVSSELNRLRKIALYRTFQVDPTKRITIEQLL</Hsp_hseq>
      <Hsp_midline>++ +L+   Q +H  G  H DLKPEN+L    G +K+ DFG+++       K V  +    GS  YVAPE    F     Y P   D WS G++   MV G+       P  + +    +S IK+  +F  F     VS E      + L +        R+T ++LL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>82</Hit_num>
  <Hit_id>YKL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:347214:349136:-1 gene:YKL048C transcript:YKL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ELM1 description:Serine/threonine protein kinase; regulates the orientation checkpoint, the morphogenesis checkpoint and the metabolic switch from fermentative to oxidative metabolism by phosphorylating the activation loop of Kin4p, Hsl1p and Snf4p respectively; cooperates with Hsl7p in recruiting Hsl1p to the septin ring, a prerequisite for subsequent recruitment, phosphorylation, and degradation of Swe1p; forms part of the bud neck ring; regulates cytokinesis [Source:SGD;Acc:S000001531]</Hit_def>
  <Hit_accession>YKL048C</Hit_accession>
  <Hit_len>640</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>5.5668e-09</Hsp_evalue>
      <Hsp_query-from>827</Hsp_query-from>
      <Hsp_query-to>1126</Hsp_query-to>
      <Hsp_hit-from>240</Hsp_hit-from>
      <Hsp_hit-to>354</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>121</Hsp_align-len>
      <Hsp_qseq>LAELVLATQSLHQMGYVHRDLKPENVLVDRTGHI-KLADFGSAA-----------------KLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSY---GPECDWWSVGVIAYEMVYGKTPF</Hsp_qseq>
      <Hsp_hseq>LEDMTKGLEYLHSQGCIHRDIKPSNILLDEEEKVAKLSDFGSCIFTPQSLPFSDANFEDCFQRELNKIV------GTPAFIAPELCHLGNSKRDFVTDGFKLDIWSLGVTLYCLLYNELPF</Hsp_hseq>
      <Hsp_midline>L ++    + LH  G +HRD+KP N+L+D    + KL+DFGS                   +   NK+V      G+P ++APE+    + K  +   G + D WS+GV  Y ++Y + PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>83</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>7.96242e-09</Hsp_evalue>
      <Hsp_query-from>800</Hsp_query-from>
      <Hsp_query-to>1300</Hsp_query-to>
      <Hsp_hit-from>125</Hsp_hit-from>
      <Hsp_hit-to>319</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>198</Hsp_align-len>
      <Hsp_qseq>LDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPE---GSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNI-----------------KNFQKFVR----FPSEPAVSV------EFVDLVKGLLC-GRVDRLTPDKLLCHPFFA</Hsp_qseq>
      <Hsp_hseq>LTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQG---YTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPYLS</Hsp_hseq>
      <Hsp_midline>L ++  + +  +++   + +H    +HRDLKP N+LV+    +K+ DFG A   + N + +S+       +  Y APE++ S+ G   Y    D WS G I  E + GK  F        ++ I                 KN Q ++      P  P V++      + +DL++ +L      R+T D+ L HP+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>84</Hit_num>
  <Hit_id>YIL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:183937:186369:1 gene:YIL095W transcript:YIL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRK1 description:Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton and reduces endocytic ability of cell through the phosphorylation of the Pan1p-Sla1p-End3p protein complex; PRK1 has a paralog, ARK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001357]</Hit_def>
  <Hit_accession>YIL095W</Hit_accession>
  <Hit_len>810</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>1.66344e-08</Hsp_evalue>
      <Hsp_query-from>758</Hsp_query-from>
      <Hsp_query-to>1126</Hsp_query-to>
      <Hsp_hit-from>114</Hsp_hit-from>
      <Hsp_hit-to>245</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>133</Hsp_align-len>
      <Hsp_qseq>GGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLH--QMGYVHRDLKPENVLVDRTGHIKLADFGSAAKL--------NANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPF</Hsp_qseq>
      <Hsp_hseq>GGLIDFMNTRLQNRLQESEILEIMSQTVQGITAMHALQPPLIHRDIKIENVLISHDGLYKVCDFGSVSGVIRPPRNTQEFNYVQHDILTNTTAQYRSPEMIDLYRGL-PIDEKSDIWALGVFLYKICYYTTPF</Hsp_hseq>
      <Hsp_midline>GG +  +  R +++L ES +   +++ V    ++H  Q   +HRD+K ENVL+   G  K+ DFGS + +          N +    L   +  Y +PE++  + G      + D W++GV  Y++ Y  TPF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>85</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>1.79253e-08</Hsp_evalue>
      <Hsp_query-from>503</Hsp_query-from>
      <Hsp_query-to>1126</Hsp_query-to>
      <Hsp_hit-from>10</Hsp_hit-from>
      <Hsp_hit-to>223</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>235</Hsp_align-len>
      <Hsp_qseq>SSDFEVRGVVSRGHHSEVQVVRERATGDV-------------YAMKVLQKSLLL----HRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPD----------YVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPF</Hsp_qseq>
      <Hsp_hseq>SSDFQLKSLLGEGAYGVVCSATHKPTGEIVAIKKIEPFDKPLFALRTLREIKILKHFKHENIITIFNIQRPD--------------SFENFNEVYIIQELM-QTDLHRVIS--TQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSE-PTGQQSGMTEYVATRWYRAPEVMLT---SAKYSRAMDVWSCGCILAELFLRRPIF</Hsp_hseq>
      <Hsp_midline>SSDF+++ ++  G +  V     + TG++             +A++ L++  +L    H + + +F  +R                +F++ + +Y+++      DL  ++      L +  +++++ + + A + LH    +HRDLKP N+L++    +K+ DFG A  ++ +   +S+ P G             Y APEV+ +      Y    D WS G I  E+   +  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>86</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>1.91342e-08</Hsp_evalue>
      <Hsp_query-from>530</Hsp_query-from>
      <Hsp_query-to>1108</Hsp_query-to>
      <Hsp_hit-from>450</Hsp_hit-from>
      <Hsp_hit-to>647</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>212</Hsp_align-len>
      <Hsp_qseq>VSRGHHSEVQVVRERATGDVYAMKVLQ-------KSLLLH-------RDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRY----EDQLDESMVRFYLAELVLATQSLHQMGY-VHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMV</Hsp_qseq>
      <Hsp_hseq>IGKGQFSTVYQVTFAQTNKKYAIKAIKPNKYNSLKRILLEIKILNEVTNQITMDQEGKEYIIDYISSW------KFQN--SYYIMTELCENGNLDGFLQEQVIAKKKRLEDWRIWKIIVELSLALRFIHDSCHIVHLDLKPANVMITFEGNLKLGDFGMATHLPLED--KSFENEGDREYIAPEIISD----CTYDYKADIFSLGLMIVEIA</Hsp_hseq>
      <Hsp_midline>+ +G  S V  V    T   YA+K ++       K +LL         + + + +E ++ +    S W       FQ+  + Y++      G+L G L       + +L++  +   + EL LA + +H   + VH DLKP NV++   G++KL DFG A  L       S   EG  +Y+APE++S      +Y  + D +S+G++  E+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>87</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>2.2911e-08</Hsp_evalue>
      <Hsp_query-from>734</Hsp_query-from>
      <Hsp_query-to>1129</Hsp_query-to>
      <Hsp_hit-from>157</Hsp_hit-from>
      <Hsp_hit-to>290</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>YLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVL---VDRTGHIKLADFGSAA--KLNANKMVSSKLPEGSPDYVAPEVL-SSFSGKGSYGP-EC---DWWSVGVIAYEMVYGKTPFA</Hsp_qseq>
      <Hsp_hseq>YIIMEYCSGGDLYEAIKADAVPKKTKSITHIITQIMDAIEYVHNKGIYHRDIKPENILISGIDWT--IKLTDWGLATTDKTSMDRNV------GSERYMSPELFDSNLDIKERKEPYDCAKVDLWAMGIVFLNIVFHKNPFS</Hsp_hseq>
      <Hsp_midline>Y++  Y  GGDL   +           +   + +++ A + +H  G  HRD+KPEN+L   +D T  IKL D+G A   K + ++ V      GS  Y++PE+  S+   K    P +C   D W++G++   +V+ K PF+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>88</Hit_num>
  <Hit_id>YBR059C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:356861:360187:-1 gene:YBR059C transcript:YBR059C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AKL1 description:Ser-Thr protein kinase; member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization [Source:SGD;Acc:S000000263]</Hit_def>
  <Hit_accession>YBR059C</Hit_accession>
  <Hit_len>1108</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>2.74582e-08</Hsp_evalue>
      <Hsp_query-from>755</Hsp_query-from>
      <Hsp_query-to>1126</Hsp_query-to>
      <Hsp_hit-from>135</Hsp_hit-from>
      <Hsp_hit-to>268</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>140</Hsp_align-len>
      <Hsp_qseq>PGGDLLGLLG-RYEDQLDESMVRFYLAELVLATQSLHQM--GYVHRDLKPENVLVDRTGHIKLADFGSA-------------AKLNANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPF</Hsp_qseq>
      <Hsp_hseq>PNKSLLDYMNQRLSTKLTEAEIVKIMYDVALSISQMHYLPVSLIHRDIKIENVLVDAKNNFKLADFGSTSTCFPIVTTHQDIALLTQNIYVHT-----TPQYRSPEMIDLYRCL-PINEKSDIWALGVFLYKLLFFTTPF</Hsp_hseq>
      <Hsp_midline>P   LL  +  R   +L E+ +   + ++ L+   +H +    +HRD+K ENVLVD   + KLADFGS              A L  N  V +     +P Y +PE++  +        + D W++GV  Y++++  TPF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>89</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>3.19911e-08</Hsp_evalue>
      <Hsp_query-from>800</Hsp_query-from>
      <Hsp_query-to>1129</Hsp_query-to>
      <Hsp_hit-from>108</Hsp_hit-from>
      <Hsp_hit-to>213</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>116</Hsp_align-len>
      <Hsp_qseq>LDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLN------ANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFA</Hsp_qseq>
      <Hsp_hseq>LGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLW-------YRAPEVL---LGGKQYSTGVDTWSIGCIFAEMCNRKPIFS</Hsp_hseq>
      <Hsp_midline>L   +V+ ++ +L       H    +HRDLKP+N+L+++ G++KL DFG A           +++V+         Y APEVL    G   Y    D WS+G I  EM   K  F+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>90</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>5.25327e-08</Hsp_evalue>
      <Hsp_query-from>815</Hsp_query-from>
      <Hsp_query-to>1195</Hsp_query-to>
      <Hsp_hit-from>254</Hsp_hit-from>
      <Hsp_hit-to>400</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>149</Hsp_align-len>
      <Hsp_qseq>VRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPE---------GSPDYVAPEVL--------SSFSGKGSYGPEC-----DWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPS</Hsp_qseq>
      <Hsp_hseq>TREILRGVVLGLEYLHYQGIIHRDIKPANLLISGDGTVKISDFGVSLAASSTNSSDSSESLDELELAKTVGTPAFFAPEMCLGEDAFTRYNLTKENLFRGSCISFMIDIWAVGVTLYCLLFGMLPFFSDFELKLFEKIVN--DPLKFPT</Hsp_hseq>
      <Hsp_midline> R  L  +VL  + LH  G +HRD+KP N+L+   G +K++DFG +   ++     S             G+P + APE+          + + +  +   C     D W+VGV  Y +++G  PF      K    I N    ++FP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>91</Hit_num>
  <Hit_id>YDR247W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:956013:957398:1 gene:YDR247W transcript:YDR247W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VHS1 description:Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; VHS1 has a paralog, SKS1, that arose from the whole genome duplication [Source:SGD;Acc:S000002655]</Hit_def>
  <Hit_accession>YDR247W</Hit_accession>
  <Hit_len>461</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>8.32804e-08</Hsp_evalue>
      <Hsp_query-from>734</Hsp_query-from>
      <Hsp_query-to>1147</Hsp_query-to>
      <Hsp_hit-from>135</Hsp_hit-from>
      <Hsp_hit-to>281</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>151</Hsp_align-len>
      <Hsp_qseq>YLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYVAPEVLSSFSGK-----------GSYGPEC--DWWSVGVIAYEMVYGKTPFAEGISTK</Hsp_qseq>
      <Hsp_hseq>FIVMDYYPTDLFTSIVDNRHFVTNGLLVKKVFLQICSALNYCHEHGIYHCDIKPENLLLDTEDNVFLCDFGLST---TSTYIKPNVCIGSSYYMPPERI-SFDGRVSSSKSGGHKLGKVCPSCNGDLWSLGIILINLTCIRNPWLKADKTE</Hsp_hseq>
      <Hsp_midline>++V  Y+P      ++       +  +V+    ++  A    H+ G  H D+KPEN+L+D   ++ L DFG +     +  +   +  GS  Y+ PE + SF G+           G   P C  D WS+G+I   +   + P+ +   T+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>92</Hit_num>
  <Hit_id>YNL183C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:293137:295509:-1 gene:YNL183C transcript:YNL183C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NPR1 description:Protein kinase; stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p; negatively regulates Ldb19p-mediated endocytosis through phosphorylation of Ldb19p, which prevents its association with the plasma membrane; Npr1p activity is negatively regulated via phosphorylation by the TOR complex; NPR1 has a paralog, PRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005127]</Hit_def>
  <Hit_accession>YNL183C</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>1.10765e-07</Hsp_evalue>
      <Hsp_query-from>764</Hsp_query-from>
      <Hsp_query-to>1126</Hsp_query-to>
      <Hsp_hit-from>523</Hsp_hit-from>
      <Hsp_hit-to>641</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>125</Hsp_align-len>
      <Hsp_qseq>DLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLN---ANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPE-CDWWSVGVIAYEMVYGKTPF</Hsp_qseq>
      <Hsp_hseq>DLFAIVMSNKMSYEEICCCF--KQILTGVQYLHSIGLAHRDLKLDNCVINEKGIVKLIDFGAAVVFSYPFSKNLVEASGIVGSDPYLAPEVCI----FAKYDPRPVDIWSSAIIFACMILKKFPW</Hsp_hseq>
      <Hsp_midline>DL  ++   +   +E    F   +++   Q LH +G  HRDLK +N +++  G +KL DFG+A   +   +  +V +    GS  Y+APEV         Y P   D WS  +I   M+  K P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>93</Hit_num>
  <Hit_id>YJR059W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:545787:548243:1 gene:YJR059W transcript:YJR059W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK2 description:Serine/threonine protein kinase; involved in regulation of ion transport across plasma membrane; carboxyl terminus is essential for glucose-dependent Pma1p activation via phosphorylation of Pma1p-Ser899; enhances spermine uptake; PTK2 has a paralog, PTK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003820]</Hit_def>
  <Hit_accession>YJR059W</Hit_accession>
  <Hit_len>818</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>1.69966e-07</Hsp_evalue>
      <Hsp_query-from>530</Hsp_query-from>
      <Hsp_query-to>1144</Hsp_query-to>
      <Hsp_hit-from>261</Hsp_hit-from>
      <Hsp_hit-to>488</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>241</Hsp_align-len>
      <Hsp_qseq>VSRGHHSEVQVVRER-ATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLT--HLQYAFQDEDNLYLVR----PYHPGG----------DLLGLLGRY---EDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLN------ANKMVSSKLPEGSPDYVAPEVLSSFSGKGSYGPE----------CDWWSVGVIAYEMVYGKTPFAEGIST</Hsp_qseq>
      <Hsp_hseq>IGSGGSSEVRKVKSSYRQKDVYALKKL---------NMIYHESPEKFYKRCSKEFIIAKHLSHNVHITNTFYLLKVPTTTYTTRGWGFIMELGVKDLFQLMERTGWKNVPFNEKYCLF--KQVAQGIKFCHDNGIAHRDLKPENVLISKEGICKLTDFGISDWYHVIPHDYTSPVKTCQGMIGSPPYTPPEVM-YFDAKKHY-PEKFQKPYNPLAMDSYALGIMLITMINNIIPFIDSCNT</Hsp_hseq>
      <Hsp_midline>+  G  SEV+ V+      DVYA+K L         N+   E       R S  ++   HL +     +  YL++     Y   G          DL  L+ R        +E    F   ++    +  H  G  HRDLKPENVL+ + G  KL DFG +   +       + + + +   GSP Y  PEV+  F  K  Y PE           D +++G++   M+    PF +  +T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>94</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>2.75739e-07</Hsp_evalue>
      <Hsp_query-from>620</Hsp_query-from>
      <Hsp_query-to>1135</Hsp_query-to>
      <Hsp_hit-from>114</Hsp_hit-from>
      <Hsp_hit-to>285</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>184</Hsp_align-len>
      <Hsp_qseq>LLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVRPYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPD------------YVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEG</Hsp_qseq>
      <Hsp_hseq>LNHKNIIKLIEMVYDHSPDITNAASSNLHKSF------YMILPYM-VADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFG-LARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELV---LGDKQYTTAVDIWGVGCVFAEF-FEKKPILQG</Hsp_hseq>
      <Hsp_midline>L H++ + L E   D     ++   ++L  +F      Y++ PY    DL G+L      L+   ++  + +++     +H   ++HRD+K  N+L+D  G +KLADFG  A+L      + K P G+              Y APE++    G   Y    D W VG +  E  + K P  +G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>95</Hit_num>
  <Hit_id>YKL198C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:68232:70220:-1 gene:YKL198C transcript:YKL198C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK1 description:Putative serine/threonine protein kinase; regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein; PTK1 has a paralog, PTK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001681]</Hit_def>
  <Hit_accession>YKL198C</Hit_accession>
  <Hit_len>662</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>3.06474e-07</Hsp_evalue>
      <Hsp_query-from>827</Hsp_query-from>
      <Hsp_query-to>1150</Hsp_query-to>
      <Hsp_hit-from>310</Hsp_hit-from>
      <Hsp_hit-to>431</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>122</Hsp_align-len>
      <Hsp_qseq>LAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKM-VSSKLPE-----GSPDYVAPEVLSSFSGK-------GSYGPEC-DWWSVGVIAYEMVYGKTPFAEGISTKT</Hsp_qseq>
      <Hsp_hseq>FKQVACGVKFCHDQGIAHRDLKPENVLLSPDGVCKLTDFGISDWYHTDPHDLSSPVKKCAGMIGSPPYAPPEVMFYDSKKHYDTELQQPYDPRALDCYGLGIILMTLVNNVIPFLESCSFDT</Hsp_hseq>
      <Hsp_midline>  ++    +  H  G  HRDLKPENVL+   G  KL DFG +   + +   +SS + +     GSP Y  PEV+   S K         Y P   D + +G+I   +V    PF E  S  T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>96</Hit_num>
  <Hit_id>YPL236C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:101608:102702:-1 gene:YPL236C transcript:YPL236C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ENV7 description:Vacuolar membrane protein kinase; negatively regulates membrane fusion; associates with vacuolar membrane through palmitoylation of one or more cysteines in consensus sequence; vacuolar membrane association is essential to its kinase activity; mutant shows defect in CPY processing; ortholog of human serine/threonine kinase 16 (STK16) [Source:SGD;Acc:S000006157]</Hit_def>
  <Hit_accession>YPL236C</Hit_accession>
  <Hit_len>364</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>1.51684e-06</Hsp_evalue>
      <Hsp_query-from>839</Hsp_query-from>
      <Hsp_query-to>1258</Hsp_query-to>
      <Hsp_hit-from>200</Hsp_hit-from>
      <Hsp_hit-to>345</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>150</Hsp_align-len>
      <Hsp_qseq>VLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLNA---NKMVSSKLPEGSPD-----YVAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPF--AEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLVKGLLCGRVD</Hsp_qseq>
      <Hsp_hseq>MLSSNSAGSIAYAHRDITPSNILFSSDGLPVIGDLGSCSQADITIENRHQLSELQEWVNDNCTLPYTPPELL-NLKLNQVLSSKVDIWSLGCTFYTLMFGISPFEREEQIHGASLTYAINTGKY-SFPRNSRFSEGLLSVIKK--CIQVD</Hsp_hseq>
      <Hsp_midline>+L++ S   + Y HRD+ P N+L    G   + D GS ++ +    N+   S+L E   D     Y  PE+L +         + D WS+G   Y +++G +PF   E I   +++   N  K+  FP     S   + ++K   C +VD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>107</Statistics_hsp-len>
      <Statistics_eff-space>5672010323</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

