<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0062796-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.66 eAED:0.68 QI:0|-1|0|1|-1|1|1|0|130</BlastOutput_query-def>
  <BlastOutput_query-len>393</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0062796-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.66 eAED:0.68 QI:0|-1|0|1|-1|1|1|0|130</Iteration_query-def>
  <Iteration_query-len>393</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>79</Statistics_hsp-len>
      <Statistics_eff-space>124418684</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0039127-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|1|1|2|75|132</Iteration_query-def>
  <Iteration_query-len>474</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>82</Statistics_hsp-len>
      <Statistics_eff-space>180337892</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0038331-RA transcript Note:&quot;Similar to tent5c Terminal nucleotidyltransferase 5C (Danio rerio)&quot; offset:0 AED:0.69 eAED:0.93 QI:0|0|0|0.66|0|0.33|3|0|460</Iteration_query-def>
  <Iteration_query-len>1383</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>93</Statistics_hsp-len>
      <Statistics_eff-space>846498256</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0015780-RA transcript Note:&quot;Similar to CPED1 Cadherin-like and PC-esterase domain-containing protein 1 (Homo sapiens)&quot; offset:0 AED:0.62 eAED:0.62 QI:0|0|0|0.11|0.37|0.55|9|0|363</Iteration_query-def>
  <Iteration_query-len>1092</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>631576491</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0015778-RA transcript Note:&quot;Similar to ZSCAN32 Zinc finger and SCAN domain-containing protein 32 (Homo sapiens)&quot; offset:0 AED:0.44 eAED:0.52 QI:0|0|0|1|0.5|0.33|3|0|159</Iteration_query-def>
  <Iteration_query-len>480</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YOR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:534075:536819:1 gene:YOR113W transcript:YOR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AZF1 description:Zinc-finger transcription factor; involved in diauxic shift; in the presence of glucose, activates transcription of genes involved in growth and carbon metabolism; in nonfermentable carbon sources, activates transcription of genes involved in maintenance of cell wall integrity; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000005639]</Hit_def>
  <Hit_accession>YOR113W</Hit_accession>
  <Hit_len>914</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.0998</Hsp_bit-score>
      <Hsp_score>183</Hsp_score>
      <Hsp_evalue>5.90047e-17</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>249</Hsp_query-to>
      <Hsp_hit-from>595</Hsp_hit-from>
      <Hsp_hit-to>676</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>44</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>82</Hsp_align-len>
      <Hsp_qseq>CTACGKVFKHLSSLKVHRTIHTGERLHVCDECGKGFSDTSNLKKHVRTHTGERPYKCGVCAKGFSQASTMRIHQKMHSLETP</Hsp_qseq>
      <Hsp_hseq>CPYCHRLFSQATHLEVHVRSHIGYKPFVCDYCGKRFTQGGNLRTHERLHTGEKPYSCDICDKKFSRKGNLAAHLVTHQKLKP</Hsp_hseq>
      <Hsp_midline>C  C ++F   + L+VH   H G +  VCD CGK F+   NL+ H R HTGE+PY C +C K FS+   +  H   H    P</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>68.5514</Hsp_bit-score>
      <Hsp_score>166</Hsp_score>
      <Hsp_evalue>1.07998e-14</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>246</Hsp_query-to>
      <Hsp_hit-from>622</Hsp_hit-from>
      <Hsp_hit-to>705</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>MCTACGKVFKHLSSLKVHRTIHTGERLHVCDECGKGFSDTSNLKKHVRTHTGERPYKCGV--CAKGFSQASTMRIHQKMHSLET</Hsp_qseq>
      <Hsp_hseq>VCDYCGKRFTQGGNLRTHERLHTGEKPYSCDICDKKFSRKGNLAAHLVTHQKLKPFVCKLENCNKTFTQLGNMKAHQNRFHKET</Hsp_hseq>
      <Hsp_midline>+C  CGK F    +L+ H  +HTGE+ + CD C K FS   NL  H+ TH   +P+ C +  C K F+Q   M+ HQ     ET</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>58.5362</Hsp_bit-score>
      <Hsp_score>140</Hsp_score>
      <Hsp_evalue>2.98396e-11</Hsp_evalue>
      <Hsp_query-from>82</Hsp_query-from>
      <Hsp_query-to>249</Hsp_query-to>
      <Hsp_hit-from>593</Hsp_hit-from>
      <Hsp_hit-to>648</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>22</Hsp_identity>
      <Hsp_positive>35</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>56</Hsp_align-len>
      <Hsp_qseq>HVCDECGKGFSDTSNLKKHVRTHTGERPYKCGVCAKGFSQASTMRIHQKMHSLETP</Hsp_qseq>
      <Hsp_hseq>HECPYCHRLFSQATHLEVHVRSHIGYKPFVCDYCGKRFTQGGNLRTHERLHTGEKP</Hsp_hseq>
      <Hsp_midline>H C  C + FS  ++L+ HVR+H G +P+ C  C K F+Q   +R H+++H+ E P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YJL056C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:330431:333073:-1 gene:YJL056C transcript:YJL056C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZAP1 description:Zinc-regulated transcription factor; binds to zinc-responsive promoters to induce transcription of certain genes in presence of zinc, represses other genes in low zinc; regulates its own transcription; contains seven zinc-finger domains [Source:SGD;Acc:S000003592]</Hit_def>
  <Hit_accession>YJL056C</Hit_accession>
  <Hit_len>880</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.8626</Hsp_bit-score>
      <Hsp_score>172</Hsp_score>
      <Hsp_evalue>1.58344e-15</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>234</Hsp_query-to>
      <Hsp_hit-from>770</Hsp_hit-from>
      <Hsp_hit-to>846</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>77</Hsp_align-len>
      <Hsp_qseq>CTACGKVFKHLSSLKVHRTIHTGERLHVCDECGKGFSDTSNLKKHVRTHTGERPYKCGVCAKGFSQASTMRIHQKMH</Hsp_qseq>
      <Hsp_hseq>CKTCKRCFSSEETLVQHTRTHSGEKPYKCHICNKKFAISSSLKIHIRTHTGEKPLQCKICGKRFNESSNLSKHIKTH</Hsp_hseq>
      <Hsp_midline>C  C + F    +L  H   H+GE+ + C  C K F+ +S+LK H+RTHTGE+P +C +C K F+++S +  H K H</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>1.57964e-14</Hsp_evalue>
      <Hsp_query-from>13</Hsp_query-from>
      <Hsp_query-to>252</Hsp_query-to>
      <Hsp_hit-from>745</Hsp_hit-from>
      <Hsp_hit-to>824</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>80</Hsp_align-len>
      <Hsp_qseq>CGKVFKHLSSLKVHRTIHTGERLHVCDECGKGFSDTSNLKKHVRTHTGERPYKCGVCAKGFSQASTMRIHQKMHSLETPV</Hsp_qseq>
      <Hsp_hseq>CHRTFPQRQKLIRHLKVHSKYKPYKCKTCKRCFSSEETLVQHTRTHSGEKPYKCHICNKKFAISSSLKIHIRTHTGEKPL</Hsp_hseq>
      <Hsp_midline>C + F     L  H  +H+  + + C  C + FS    L +H RTH+GE+PYKC +C K F+ +S+++IH + H+ E P+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>7.04078e-13</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>243</Hsp_query-to>
      <Hsp_hit-from>798</Hsp_hit-from>
      <Hsp_hit-to>875</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>80</Hsp_align-len>
      <Hsp_qseq>CTACGKVFKHLSSLKVHRTIHTGERLHVCDECGKGFSDTSNLKKHVRTHTGERPYKCGVCAKGFSQASTMRIHQKMHSLE</Hsp_qseq>
      <Hsp_hseq>CHICNKKFAISSSLKIHIRTHTGEKPLQCKICGKRFNESSNLSKHIKTH--QKKYKCSDCSKSFDDLGKLNSQKVKCALE</Hsp_hseq>
      <Hsp_midline>C  C K F   SSLK+H   HTGE+   C  CGK F+++SNL KH++TH  ++ YKC  C+K F     +   +   +LE</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>4</Hsp_num>
      <Hsp_bit-score>46.2098</Hsp_bit-score>
      <Hsp_score>108</Hsp_score>
      <Hsp_evalue>5.2799e-07</Hsp_evalue>
      <Hsp_query-from>10</Hsp_query-from>
      <Hsp_query-to>249</Hsp_query-to>
      <Hsp_hit-from>711</Hsp_hit-from>
      <Hsp_hit-to>795</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>26</Hsp_identity>
      <Hsp_positive>37</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>85</Hsp_align-len>
      <Hsp_qseq>ACGKVFKHLSSLK-----VHRTIHTGERLHVCDECGKGFSDTSNLKKHVRTHTGERPYKCGVCAKGFSQASTMRIHQKMHSLETP</Hsp_qseq>
      <Hsp_hseq>GCNKSFSSAQELNDHLEAVHLTRGKSEYQCLWHDCHRTFPQRQKLIRHLKVHSKYKPYKCKTCKRCFSSEETLVQHTRTHSGEKP</Hsp_hseq>
      <Hsp_midline> C K F     L      VH T    E   +  +C + F     L +H++ H+  +PYKC  C + FS   T+  H + HS E P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YNL027W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:579580:581616:1 gene:YNL027W transcript:YNL027W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CRZ1 description:Transcription factor, activates transcription of stress response genes; nuclear localization is positively regulated by calcineurin-mediated dephosphorylation; rapidly localizes to the nucleus under blue light stress; can be activated in stochastic pulses of nuclear localization in response to calcium [Source:SGD;Acc:S000004972]</Hit_def>
  <Hit_accession>YNL027W</Hit_accession>
  <Hit_len>678</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>1.15068e-12</Hsp_evalue>
      <Hsp_query-from>88</Hsp_query-from>
      <Hsp_query-to>237</Hsp_query-to>
      <Hsp_hit-from>571</Hsp_hit-from>
      <Hsp_hit-to>620</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>33</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>50</Hsp_align-len>
      <Hsp_qseq>CDECGKGFSDTSNLKKHVRTHTGERPYKCGVCAKGFSQASTMRIHQKMHS</Hsp_qseq>
      <Hsp_hseq>CDVCGKKFTRPYNLKSHLRTHTNERPFICSICGKAFARQHDRKRHEDLHT</Hsp_hseq>
      <Hsp_midline>CD CGK F+   NLK H+RTHT ERP+ C +C K F++    + H+ +H+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>2.38712e-12</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>282</Hsp_query-to>
      <Hsp_hit-from>571</Hsp_hit-from>
      <Hsp_hit-to>675</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>105</Hsp_align-len>
      <Hsp_qseq>CTACGKVFKHLSSLKVHRTIHTGERLHVCDECGKGFSDTSNLKKHVRTHTGERPYKCG---------VCAKGFSQASTMRIHQKMHSLE---TPVPGEEVQVEAG</Hsp_qseq>
      <Hsp_hseq>CDVCGKKFTRPYNLKSHLRTHTNERPFICSICGKAFARQHDRKRHEDLHTGKKRYVCGGKLKDGKPWGCGKKFARSDALGRHFKTESGRRCITPLYEEARQEKSG</Hsp_hseq>
      <Hsp_midline>C  CGK F    +LK H   HT ER  +C  CGK F+   + K+H   HTG++ Y CG          C K F+++  +  H K  S     TP+  E  Q ++G</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>45.8246</Hsp_bit-score>
      <Hsp_score>107</Hsp_score>
      <Hsp_evalue>6.65689e-07</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>162</Hsp_query-to>
      <Hsp_hit-from>598</Hsp_hit-from>
      <Hsp_hit-to>660</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>32</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>63</Hsp_align-len>
      <Hsp_qseq>MCTACGKVFKHLSSLKVHRTIHTGERLHVCD---------ECGKGFSDTSNLKKHVRTHTGER</Hsp_qseq>
      <Hsp_hseq>ICSICGKAFARQHDRKRHEDLHTGKKRYVCGGKLKDGKPWGCGKKFARSDALGRHFKTESGRR</Hsp_hseq>
      <Hsp_midline>+C+ CGK F      K H  +HTG++ +VC           CGK F+ +  L +H +T +G R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YPR186C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:909733:911022:-1 gene:YPR186C transcript:YPR186C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PZF1 description:Transcription factor IIIA (TFIIIA); essential DNA binding protein required for transcription of 5S rRNA by RNA polymerase III; not involved in transcription of other RNAP III genes; nine conserved zinc fingers; may also bind 5S rRNA [Source:SGD;Acc:S000006390]</Hit_def>
  <Hit_accession>YPR186C</Hit_accession>
  <Hit_len>429</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>5.11985e-11</Hsp_evalue>
      <Hsp_query-from>13</Hsp_query-from>
      <Hsp_query-to>261</Hsp_query-to>
      <Hsp_hit-from>56</Hsp_hit-from>
      <Hsp_hit-to>139</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>CGKVFKHLSSLKVHR-TIHTGERLHVCDECGKGFSDTSNLKKHVRTHTGERPYKCGVCAKGFSQASTMRIHQKMHSLETPVPGE</Hsp_qseq>
      <Hsp_hseq>CDKAFTRPSILTEHQLSVHQGLRAFQCDKCAKSFVKKSHLERHLYTHSDTKPFQCSYCGKGVTTRQQLKRHEVTHTKSFICPEE</Hsp_hseq>
      <Hsp_midline>C K F   S L  H+ ++H G R   CD+C K F   S+L++H+ TH+  +P++C  C KG +    ++ H+  H+     P E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YDR216W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:895035:899006:1 gene:YDR216W transcript:YDR216W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ADR1 description:Carbon source-responsive zinc-finger transcription factor; required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization [Source:SGD;Acc:S000002624]</Hit_def>
  <Hit_accession>YDR216W</Hit_accession>
  <Hit_len>1323</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>8.53212e-11</Hsp_evalue>
      <Hsp_query-from>55</Hsp_query-from>
      <Hsp_query-to>237</Hsp_query-to>
      <Hsp_hit-from>95</Hsp_hit-from>
      <Hsp_hit-to>156</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>25</Hsp_identity>
      <Hsp_positive>38</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>62</Hsp_align-len>
      <Hsp_qseq>RTIHTGERLHVCDECGKGFSDTSNLKKHVRTHTGERPYKCGVCAKGFSQASTMRIH-QKMHS</Hsp_qseq>
      <Hsp_hseq>RTPSGKLRSFVCEVCTRAFARQEHLKRHYRSHTNEKPYPCGLCNRCFTRRDLLIRHAQKIHS</Hsp_hseq>
      <Hsp_midline>RT     R  VC+ C + F+   +LK+H R+HT E+PY CG+C + F++   +  H QK+HS</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YMR182C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:624532:625167:-1 gene:YMR182C transcript:YMR182C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RGM1 description:Putative zinc finger DNA binding transcription factor; contains two N-terminal C2H2 zinc fingers and C-terminal proline rich domain; overproduction impairs cell growth and induces expression of genes involved in monosaccharide catabolism and aldehyde metabolism; regulates expression of of Y&apos; telomeric elements and subtelomeric COS genes; relocalizes to the cytosol in response to hypoxia; RGM1 has a paralog, USV1, that arose from the whole genome duplication [Source:SGD;Acc:S000004794]</Hit_def>
  <Hit_accession>YMR182C</Hit_accession>
  <Hit_len>211</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>3.90062e-10</Hsp_evalue>
      <Hsp_query-from>94</Hsp_query-from>
      <Hsp_query-to>225</Hsp_query-to>
      <Hsp_hit-from>26</Hsp_hit-from>
      <Hsp_hit-to>69</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>19</Hsp_identity>
      <Hsp_positive>30</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>44</Hsp_align-len>
      <Hsp_qseq>ECGKGFSDTSNLKKHVRTHTGERPYKCGVCAKGFSQASTMRIHQ</Hsp_qseq>
      <Hsp_hseq>DCNMSFNRTEHLARHIRKHTGEKPFQCNICLKFFSRIDNLRQHQ</Hsp_hseq>
      <Hsp_midline>+C   F+ T +L +H+R HTGE+P++C +C K FS+   +R HQ</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YMR037C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:344403:346517:-1 gene:YMR037C transcript:YMR037C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MSN2 description:Stress-responsive transcriptional activator; activated in stochastic pulses of nuclear localization in response to various stress conditions; binds DNA at stress response elements of responsive genes; relative distribution to nucleus increases upon DNA replication stress [Source:SGD;Acc:S000004640]</Hit_def>
  <Hit_accession>YMR037C</Hit_accession>
  <Hit_len>704</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>1.32659e-09</Hsp_evalue>
      <Hsp_query-from>37</Hsp_query-from>
      <Hsp_query-to>234</Hsp_query-to>
      <Hsp_hit-from>632</Hsp_hit-from>
      <Hsp_hit-to>698</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>25</Hsp_identity>
      <Hsp_positive>38</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>67</Hsp_align-len>
      <Hsp_qseq>SSLKVHRTIHTGERLHVCDECGKGFSDTSNLKKHVRT-HTGERPYKCGVCAKGFSQASTMRIHQKMH</Hsp_qseq>
      <Hsp_hseq>SSVVIESTKELEEKPFHCHICPKSFKRSEHLKRHVRSVHSNERPFACHICDKKFSRSDNLSQHIKTH</Hsp_hseq>
      <Hsp_midline>SS+ +  T    E+   C  C K F  + +LK+HVR+ H+ ERP+ C +C K FS++  +  H K H</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>6.09189e-08</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>150</Hsp_query-to>
      <Hsp_hit-from>649</Hsp_hit-from>
      <Hsp_hit-to>698</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>22</Hsp_identity>
      <Hsp_positive>29</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>50</Hsp_align-len>
      <Hsp_qseq>CTACGKVFKHLSSLKVH-RTIHTGERLHVCDECGKGFSDTSNLKKHVRTH</Hsp_qseq>
      <Hsp_hseq>CHICPKSFKRSEHLKRHVRSVHSNERPFACHICDKKFSRSDNLSQHIKTH</Hsp_hseq>
      <Hsp_midline>C  C K FK    LK H R++H+ ER   C  C K FS + NL +H++TH</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YML081W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:104777:108532:1 gene:YML081W transcript:YML081W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TDA9 description:Transcription factor that regulates acetate production; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; TDA9 has a paralog, RSF2, that arose from the whole genome duplication [Source:SGD;Acc:S000004546]</Hit_def>
  <Hit_accession>YML081W</Hit_accession>
  <Hit_len>1251</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>6.52124e-09</Hsp_evalue>
      <Hsp_query-from>46</Hsp_query-from>
      <Hsp_query-to>237</Hsp_query-to>
      <Hsp_hit-from>48</Hsp_hit-from>
      <Hsp_hit-to>113</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>26</Hsp_identity>
      <Hsp_positive>38</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>66</Hsp_align-len>
      <Hsp_qseq>KVHRTIHTGE-RLHVCDECGKGFSDTSNLKKHVRTHTGERPYKCGVCAKGFSQASTMRIHQ-KMHS</Hsp_qseq>
      <Hsp_hseq>KKSRTIKTDKPRPFLCHICTRGFVRQEHLKRHQRAHTNEKPFLCVFCGRCFARRDLVLRHQHKLHS</Hsp_hseq>
      <Hsp_midline>K  RTI T + R  +C  C +GF    +LK+H R HT E+P+ C  C + F++   +  HQ K+HS</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YGL209W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:95858:97006:1 gene:YGL209W transcript:YGL209W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MIG2 description:Zinc finger transcriptional repressor; cooperates with Mig1p in glucose-induced gene repression; under low glucose conditions relocalizes to mitochondrion, where it interacts with Ups1p, antagonizes mitochondrial fission factor Dnm1p, indicative of a role in mitochondrial fusion or regulating morphology; regulates filamentous growth in response to glucose depletion; activated in stochastic pulses of nuclear localization in response to low glucose [Source:SGD;Acc:S000003177]</Hit_def>
  <Hit_accession>YGL209W</Hit_accession>
  <Hit_len>382</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>1.01205e-08</Hsp_evalue>
      <Hsp_query-from>88</Hsp_query-from>
      <Hsp_query-to>237</Hsp_query-to>
      <Hsp_hit-from>19</Hsp_hit-from>
      <Hsp_hit-to>70</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>33</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>52</Hsp_align-len>
      <Hsp_qseq>CDECGKGFSDTSNLKKHVRTHTGERPYKCGV--CAKGFSQASTMRIHQKMHS</Hsp_qseq>
      <Hsp_hseq>CDTCHRGFHRLEHKKRHLRTHTGEKPHHCAFPGCGKSFSRSDELKRHMRTHT</Hsp_hseq>
      <Hsp_midline>CD C +GF    + K+H+RTHTGE+P+ C    C K FS++  ++ H + H+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>3.81627e-08</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>231</Hsp_query-to>
      <Hsp_hit-from>19</Hsp_hit-from>
      <Hsp_hit-to>106</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>44</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>88</Hsp_align-len>
      <Hsp_qseq>CTACGKVFKHLSSLKVHRTIHTGERLHVCDE--CGKGFSDTSNLKKHVRTHTGE---RPYKCGVCAKGF-------SQASTMRIHQKM</Hsp_qseq>
      <Hsp_hseq>CDTCHRGFHRLEHKKRHLRTHTGEKPHHCAFPGCGKSFSRSDELKRHMRTHTGQSQRRLKKASVQKQEFLTVSGIPTIASGVMIHQPI</Hsp_hseq>
      <Hsp_midline>C  C + F  L   K H   HTGE+ H C    CGK FS +  LK+H+RTHTG+   R  K  V  + F       + AS + IHQ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YKL062W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:323228:325120:1 gene:YKL062W transcript:YKL062W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MSN4 description:Stress-responsive transcriptional activator; activated in stochastic pulses of nuclear localization in response to various stress conditions; binds DNA at stress response elements of responsive genes, inducing gene expression; involved in diauxic shift [Source:SGD;Acc:S000001545]</Hit_def>
  <Hit_accession>YKL062W</Hit_accession>
  <Hit_len>630</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>1.12841e-08</Hsp_evalue>
      <Hsp_query-from>88</Hsp_query-from>
      <Hsp_query-to>234</Hsp_query-to>
      <Hsp_hit-from>575</Hsp_hit-from>
      <Hsp_hit-to>624</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>20</Hsp_identity>
      <Hsp_positive>31</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>50</Hsp_align-len>
      <Hsp_qseq>CDECGKGFSDTSNLKKHVRT-HTGERPYKCGVCAKGFSQASTMRIHQKMH</Hsp_qseq>
      <Hsp_hseq>CKDCEKAFRRSEHLKRHIRSVHSTERPFACMFCEKKFSRSDNLSQHLKTH</Hsp_hseq>
      <Hsp_midline>C +C K F  + +LK+H+R+ H+ ERP+ C  C K FS++  +  H K H</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>46.2098</Hsp_bit-score>
      <Hsp_score>108</Hsp_score>
      <Hsp_evalue>4.90155e-07</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>150</Hsp_query-to>
      <Hsp_hit-from>575</Hsp_hit-from>
      <Hsp_hit-to>624</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>29</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>50</Hsp_align-len>
      <Hsp_qseq>CTACGKVFKHLSSLKVH-RTIHTGERLHVCDECGKGFSDTSNLKKHVRTH</Hsp_qseq>
      <Hsp_hseq>CKDCEKAFRRSEHLKRHIRSVHSTERPFACMFCEKKFSRSDNLSQHLKTH</Hsp_hseq>
      <Hsp_midline>C  C K F+    LK H R++H+ ER   C  C K FS + NL +H++TH</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YGL254W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:22304:23203:1 gene:YGL254W transcript:YGL254W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FZF1 description:Transcription factor involved in sulfite metabolism; sole identified regulatory target is SSU1; overexpression suppresses sulfite-sensitivity of many unrelated mutants due to hyperactivation of SSU1, contains five zinc fingers; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003223]</Hit_def>
  <Hit_accession>YGL254W</Hit_accession>
  <Hit_len>299</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>1.15412e-08</Hsp_evalue>
      <Hsp_query-from>13</Hsp_query-from>
      <Hsp_query-to>234</Hsp_query-to>
      <Hsp_hit-from>19</Hsp_hit-from>
      <Hsp_hit-to>94</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>39</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>76</Hsp_align-len>
      <Hsp_qseq>CGKVFKHLSSLKVHRTIHTGERLHVCDE--CGKGFSDTSNLKKHVRTHTGERPYKCGVCAKGFSQASTMRIHQKMH</Hsp_qseq>
      <Hsp_hseq>CEKVYNRPSLLQQHQNSHTNQKPYHCDEPGCGKKFIRPCHLRVHKWTHSQIKPKACTLCQKRFVTNQQLRRHLNSH</Hsp_hseq>
      <Hsp_midline>C KV+   S L+ H+  HT ++ + CDE  CGK F    +L+ H  TH+  +P  C +C K F     +R H   H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YER028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:210692:211876:-1 gene:YER028C transcript:YER028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MIG3 description:Transcriptional regulator; partially nonfunctional in S288C strains but has a major role in catabolite repression and ethanol response in some other strains; involved in response to toxic agents; phosphorylation by Snf1p or the Mec1p pathway inactivates Mig3p, allowing induction of damage response genesenvironment [Source:SGD;Acc:S000000830]</Hit_def>
  <Hit_accession>YER028C</Hit_accession>
  <Hit_len>394</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>1.63231e-08</Hsp_evalue>
      <Hsp_query-from>73</Hsp_query-from>
      <Hsp_query-to>237</Hsp_query-to>
      <Hsp_hit-from>14</Hsp_hit-from>
      <Hsp_hit-to>70</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>36</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>57</Hsp_align-len>
      <Hsp_qseq>ERLHVCDECGKGFSDTSNLKKHVRTHTGERPYKCGV--CAKGFSQASTMRIHQKMHS</Hsp_qseq>
      <Hsp_hseq>QRPFRCEICSRGFHRLEHKKRHGRTHTGEKPHKCTVQGCPKSFSRSDELKRHLRTHT</Hsp_hseq>
      <Hsp_midline>+R   C+ C +GF    + K+H RTHTGE+P+KC V  C K FS++  ++ H + H+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>43.8986</Hsp_bit-score>
      <Hsp_score>102</Hsp_score>
      <Hsp_evalue>2.81664e-06</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>153</Hsp_query-to>
      <Hsp_hit-from>19</Hsp_hit-from>
      <Hsp_hit-to>70</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>28</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>52</Hsp_align-len>
      <Hsp_qseq>CTACGKVFKHLSSLKVHRTIHTGERLHVC--DECGKGFSDTSNLKKHVRTHT</Hsp_qseq>
      <Hsp_hseq>CEICSRGFHRLEHKKRHGRTHTGEKPHKCTVQGCPKSFSRSDELKRHLRTHT</Hsp_hseq>
      <Hsp_midline>C  C + F  L   K H   HTGE+ H C    C K FS +  LK+H+RTHT</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YJR127C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:658917:663059:-1 gene:YJR127C transcript:YJR127C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RSF2 description:Zinc-finger protein; involved in transcriptional control of both nuclear and mitochondrial genes, many of which specify products required for glycerol-based growth, respiration, and other functions; RSF2 has a paralog, TDA9, that arose from the whole genome duplication; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000003888]</Hit_def>
  <Hit_accession>YJR127C</Hit_accession>
  <Hit_len>1380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>5.50493e-08</Hsp_evalue>
      <Hsp_query-from>46</Hsp_query-from>
      <Hsp_query-to>237</Hsp_query-to>
      <Hsp_hit-from>138</Hsp_hit-from>
      <Hsp_hit-to>203</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>37</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>66</Hsp_align-len>
      <Hsp_qseq>KVHRTIHTGE-RLHVCDECGKGFSDTSNLKKHVRTHTGERPYKCGVCAKGFSQAS-TMRIHQKMHS</Hsp_qseq>
      <Hsp_hseq>KKSRIIKTDKPRPFLCPTCTRGFVRQEHLKRHQHSHTREKPYLCIFCGRCFARRDLVLRHQQKLHA</Hsp_hseq>
      <Hsp_midline>K  R I T + R  +C  C +GF    +LK+H  +HT E+PY C  C + F++    +R  QK+H+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YGL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:431548:433062:-1 gene:YGL035C transcript:YGL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MIG1 description:Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase; regulates filamentous growth along with Mig2p in response to glucose depletion; activated in stochastic pulses of nuclear localization, shuttling between cytosol and nucleus depending on external glucose levels and its phosphorylation state [Source:SGD;Acc:S000003003]</Hit_def>
  <Hit_accession>YGL035C</Hit_accession>
  <Hit_len>504</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.9802</Hsp_bit-score>
      <Hsp_score>110</Hsp_score>
      <Hsp_evalue>3.00552e-07</Hsp_evalue>
      <Hsp_query-from>76</Hsp_query-from>
      <Hsp_query-to>249</Hsp_query-to>
      <Hsp_hit-from>36</Hsp_hit-from>
      <Hsp_hit-to>95</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>20</Hsp_identity>
      <Hsp_positive>33</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>60</Hsp_align-len>
      <Hsp_qseq>RLHVCDECGKGFSDTSNLKKHVRTHTGERPYKCGV--CAKGFSQASTMRIHQKMHSLETP</Hsp_qseq>
      <Hsp_hseq>RPHACPICHRAFHRLEHQTRHMRIHTGEKPHACDFPGCVKRFSRSDELTRHRRIHTNSHP</Hsp_hseq>
      <Hsp_midline>R H C  C + F    +  +H+R HTGE+P+ C    C K FS++  +  H+++H+   P</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>46.595</Hsp_bit-score>
      <Hsp_score>109</Hsp_score>
      <Hsp_evalue>4.27295e-07</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>165</Hsp_query-to>
      <Hsp_hit-from>40</Hsp_hit-from>
      <Hsp_hit-to>95</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>27</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>56</Hsp_align-len>
      <Hsp_qseq>CTACGKVFKHLSSLKVHRTIHTGERLHVCD--ECGKGFSDTSNLKKHVRTHTGERP</Hsp_qseq>
      <Hsp_hseq>CPICHRAFHRLEHQTRHMRIHTGEKPHACDFPGCVKRFSRSDELTRHRRIHTNSHP</Hsp_hseq>
      <Hsp_midline>C  C + F  L     H  IHTGE+ H CD   C K FS +  L +H R HT   P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YPR015C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:590283:591026:-1 gene:YPR015C transcript:YPR015C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Putative zinc finger transcription factor; binds DNA in sequence-specific manner; overexpression causes a cell cycle delay or arrest [Source:SGD;Acc:S000006219]</Hit_def>
  <Hit_accession>YPR015C</Hit_accession>
  <Hit_len>247</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.8246</Hsp_bit-score>
      <Hsp_score>107</Hsp_score>
      <Hsp_evalue>5.29761e-07</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>150</Hsp_query-to>
      <Hsp_hit-from>187</Hsp_hit-from>
      <Hsp_hit-to>237</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>22</Hsp_identity>
      <Hsp_positive>30</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>51</Hsp_align-len>
      <Hsp_qseq>CTACGKVFKHLSSLKVHRTIHTGERLHVC--DECGKGFSDTSNLKKHVRTH</Hsp_qseq>
      <Hsp_hseq>CPICGKVCSRPSTLRTHYLIHTGDTPFKCTWEHCNKSFNVKSNMLRHLRTH</Hsp_hseq>
      <Hsp_midline>C  CGKV    S+L+ H  IHTG+    C  + C K F+  SN+ +H+RTH</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YPL230W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:115312:116487:1 gene:YPL230W transcript:YPL230W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:USV1 description:Putative transcription factor containing a C2H2 zinc finger; mutation affects transcriptional regulation of genes involved in growth on non-fermentable carbon sources, response to salt stress and cell wall biosynthesis; USV1 has a paralog, RGM1, that arose from the whole genome duplication [Source:SGD;Acc:S000006151]</Hit_def>
  <Hit_accession>YPL230W</Hit_accession>
  <Hit_len>391</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.2098</Hsp_bit-score>
      <Hsp_score>108</Hsp_score>
      <Hsp_evalue>5.43202e-07</Hsp_evalue>
      <Hsp_query-from>91</Hsp_query-from>
      <Hsp_query-to>225</Hsp_query-to>
      <Hsp_hit-from>47</Hsp_hit-from>
      <Hsp_hit-to>91</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>17</Hsp_identity>
      <Hsp_positive>28</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>45</Hsp_align-len>
      <Hsp_qseq>DECGKGFSDTSNLKKHVRTHTGERPYKCGVCAKGFSQASTMRIHQ</Hsp_qseq>
      <Hsp_hseq>DGCTMSFTRAEHLARHIRKHTGEKPFQCPACLKFFSRVDNLKQHR</Hsp_hseq>
      <Hsp_midline>D C   F+   +L +H+R HTGE+P++C  C K FS+   ++ H+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YER130C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:421115:422446:-1 gene:YER130C transcript:YER130C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:COM2 description:Transcription factor that binds IME1 Upstream Activation Signal (UAS)ru; COM2 transcription is regulated by Haa1p, Sok2p and Zap1p transcriptional activators; may bind the IME1 promoter under all growth conditions to negatively regulate its transcription in the absence of a positive regulator that binds more effectively; repressor activity may depend on phosphorylation by PKA; C. albicans homolog (MNL1) plays a role in adaptation to stress [Source:SGD;Acc:S000000932]</Hit_def>
  <Hit_accession>YER130C</Hit_accession>
  <Hit_len>443</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.8246</Hsp_bit-score>
      <Hsp_score>107</Hsp_score>
      <Hsp_evalue>6.48206e-07</Hsp_evalue>
      <Hsp_query-from>88</Hsp_query-from>
      <Hsp_query-to>237</Hsp_query-to>
      <Hsp_hit-from>391</Hsp_hit-from>
      <Hsp_hit-to>441</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>19</Hsp_identity>
      <Hsp_positive>31</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>51</Hsp_align-len>
      <Hsp_qseq>CDECGKGFSDTSNLKKHVRT-HTGERPYKCGVCAKGFSQASTMRIHQKMHS</Hsp_qseq>
      <Hsp_hseq>CEFCDRRFKRQEHLKRHVRSLHMCEKPFTCHICNKNFSRSDNLNQHVKTHA</Hsp_hseq>
      <Hsp_midline>C+ C + F    +LK+HVR+ H  E+P+ C +C K FS++  +  H K H+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>43.1282</Hsp_bit-score>
      <Hsp_score>100</Hsp_score>
      <Hsp_evalue>5.13277e-06</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>156</Hsp_query-to>
      <Hsp_hit-from>391</Hsp_hit-from>
      <Hsp_hit-to>442</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>28</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>52</Hsp_align-len>
      <Hsp_qseq>CTACGKVFKHLSSLKVH-RTIHTGERLHVCDECGKGFSDTSNLKKHVRTHTG</Hsp_qseq>
      <Hsp_hseq>CEFCDRRFKRQEHLKRHVRSLHMCEKPFTCHICNKNFSRSDNLNQHVKTHAS</Hsp_hseq>
      <Hsp_midline>C  C + FK    LK H R++H  E+   C  C K FS + NL +HV+TH  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YGR067C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:622372:624786:-1 gene:YGR067C transcript:YGR067C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Putative protein of unknown function; contains a zinc finger motif similar to that of Adr1p [Source:SGD;Acc:S000003299]</Hit_def>
  <Hit_accession>YGR067C</Hit_accession>
  <Hit_len>804</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.8246</Hsp_bit-score>
      <Hsp_score>107</Hsp_score>
      <Hsp_evalue>8.88968e-07</Hsp_evalue>
      <Hsp_query-from>70</Hsp_query-from>
      <Hsp_query-to>390</Hsp_query-to>
      <Hsp_hit-from>4</Hsp_hit-from>
      <Hsp_hit-to>97</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>108</Hsp_align-len>
      <Hsp_qseq>GERLHVCDECGKGFSDTSNLKKHVRTHTGERPYKCGVCAKGFSQASTMRIH-QKMHSLETPVPGEEVQVEAGSYELPDEMGPPGDGPVPLGWVDGEEDALGDRDVESE</Hsp_qseq>
      <Hsp_hseq>GQKKYICSFCLKPFSRSEHKIRHERSHAGVKPFQCQVCKHSFVRRDLLQRHIRTVHR----------TFLLSSY--ASMTGDKADIPVSLGV--GDVDSTSPRDIKME</Hsp_hseq>
      <Hsp_midline>G++ ++C  C K FS + +  +H R+H G +P++C VC   F +   ++ H + +H                SY      G   D PV LG   G+ D+   RD++ E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YPL038W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:480535:481068:1 gene:YPL038W transcript:YPL038W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MET31 description:Zinc-finger DNA-binding transcription factor; targets strong transcriptional activator Met4p to promoters of sulfur metabolic genes; involved in transcriptional regulation of the methionine biosynthetic genes; feedforward loop controlling expression of MET32 and the lack of such a loop for MET31 may account for the differential actions of Met31p and Met32p; MET31 has a paralog, MET32, that arose from the whole genome duplication [Source:SGD;Acc:S000005959]</Hit_def>
  <Hit_accession>YPL038W</Hit_accession>
  <Hit_len>177</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>43.8986</Hsp_bit-score>
      <Hsp_score>102</Hsp_score>
      <Hsp_evalue>1.61019e-06</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>171</Hsp_query-to>
      <Hsp_hit-from>97</Hsp_hit-from>
      <Hsp_hit-to>152</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>28</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>56</Hsp_align-len>
      <Hsp_qseq>CTACGKVFKHLSSLKVHRTIHTGERLHVCDECGKGFSDTSNLKKHVRTHTGERPYK</Hsp_qseq>
      <Hsp_hseq>CAKCQLKFSRSSDLRRHEKVHSLVLPHICSNCGKGFARKDALKRHSNTLTCQRNRK</Hsp_hseq>
      <Hsp_midline>C  C   F   S L+ H  +H+    H+C  CGKGF+    LK+H  T T +R  K</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>42.743</Hsp_bit-score>
      <Hsp_score>99</Hsp_score>
      <Hsp_evalue>3.69632e-06</Hsp_evalue>
      <Hsp_query-from>70</Hsp_query-from>
      <Hsp_query-to>222</Hsp_query-to>
      <Hsp_hit-from>91</Hsp_hit-from>
      <Hsp_hit-to>141</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>17</Hsp_identity>
      <Hsp_positive>31</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>51</Hsp_align-len>
      <Hsp_qseq>GERLHVCDECGKGFSDTSNLKKHVRTHTGERPYKCGVCAKGFSQASTMRIH</Hsp_qseq>
      <Hsp_hseq>GAQLYSCAKCQLKFSRSSDLRRHEKVHSLVLPHICSNCGKGFARKDALKRH</Hsp_hseq>
      <Hsp_midline>G +L+ C +C   FS +S+L++H + H+   P+ C  C KGF++   ++ H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YPR013C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:584632:585585:-1 gene:YPR013C transcript:YPR013C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMR3 description:Putative zinc finger protein; YPR013C is not an essential gene [Source:SGD;Acc:S000006217]</Hit_def>
  <Hit_accession>YPR013C</Hit_accession>
  <Hit_len>317</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>44.2838</Hsp_bit-score>
      <Hsp_score>103</Hsp_score>
      <Hsp_evalue>2.00513e-06</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>162</Hsp_query-to>
      <Hsp_hit-from>256</Hsp_hit-from>
      <Hsp_hit-to>310</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>32</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>55</Hsp_align-len>
      <Hsp_qseq>CTACGKVFKHLSSLKVHRTIHTGERLHVC--DECGKGFSDTSNLKKHVRTHTGER</Hsp_qseq>
      <Hsp_hseq>CPVCGKICSRPSTLKTHYLIHTGDTPFKCTWEGCTKSFNVKSNMLRHLKSHERKR</Hsp_hseq>
      <Hsp_midline>C  CGK+    S+LK H  IHTG+    C  + C K F+  SN+ +H+++H  +R</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>42.3578</Hsp_bit-score>
      <Hsp_score>98</Hsp_score>
      <Hsp_evalue>8.65861e-06</Hsp_evalue>
      <Hsp_query-from>34</Hsp_query-from>
      <Hsp_query-to>234</Hsp_query-to>
      <Hsp_hit-from>238</Hsp_hit-from>
      <Hsp_hit-to>306</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>26</Hsp_identity>
      <Hsp_positive>31</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>69</Hsp_align-len>
      <Hsp_qseq>LSSLKVHRTIHTGERLHVCDECGKGFSDTSNLKKHVRTHTGERPYKCGV--CAKGFSQASTMRIHQKMH</Hsp_qseq>
      <Hsp_hseq>FSDWKTDTRISSTKLRKQCPVCGKICSRPSTLKTHYLIHTGDTPFKCTWEGCTKSFNVKSNMLRHLKSH</Hsp_hseq>
      <Hsp_midline> S  K    I + +    C  CGK  S  S LK H   HTG+ P+KC    C K F+  S M  H K H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YDR253C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:963990:964565:-1 gene:YDR253C transcript:YDR253C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MET32 description:Zinc-finger DNA-binding transcription factor; involved in transcriptional regulation of the methionine biosynthetic genes; targets strong transcriptional activator Met4p to promoters of sulfur metabolic genes; feedforward loop exists in the regulation of genes controlled by Met4p and Met32p; lack of such a loop for MET31 may account for the differential actions of Met32p and Met31p; MET32 has a paralog, MET31, that arose from the whole genome duplication [Source:SGD;Acc:S000002661]</Hit_def>
  <Hit_accession>YDR253C</Hit_accession>
  <Hit_len>191</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>43.1282</Hsp_bit-score>
      <Hsp_score>100</Hsp_score>
      <Hsp_evalue>3.67642e-06</Hsp_evalue>
      <Hsp_query-from>55</Hsp_query-from>
      <Hsp_query-to>222</Hsp_query-to>
      <Hsp_hit-from>89</Hsp_hit-from>
      <Hsp_hit-to>144</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>20</Hsp_identity>
      <Hsp_positive>31</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>56</Hsp_align-len>
      <Hsp_qseq>RTIHTGERLHVCDECGKGFSDTSNLKKHVRTHTGERPYKCGVCAKGFSQASTMRIH</Hsp_qseq>
      <Hsp_hseq>RRNSTGEKRFKCAKCSLEFSRSSDLRRHEKTHFAILPNICPQCGKGFARKDALKRH</Hsp_hseq>
      <Hsp_midline>R   TGE+   C +C   FS +S+L++H +TH    P  C  C KGF++   ++ H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YDR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:637139:639823:1 gene:YDR096W transcript:YDR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIS1 description:Histone demethylase and transcription factor; regulates genes during nutrient limitation; activity modulated by proteasome-mediated proteolysis; has JmjC and JmjN domain in N-terminus that interact, promoting stability and proper transcriptional activity; contains two transactivating domains downstream of Jmj domains and a C-terminal DNA binding domain; relocalizes to the cytosol in response to hypoxia; GIS1 has a paralog, RPH1, that arose from the whole genome duplication [Source:SGD;Acc:S000002503]</Hit_def>
  <Hit_accession>YDR096W</Hit_accession>
  <Hit_len>894</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>42.743</Hsp_bit-score>
      <Hsp_score>99</Hsp_score>
      <Hsp_evalue>9.5214e-06</Hsp_evalue>
      <Hsp_query-from>76</Hsp_query-from>
      <Hsp_query-to>201</Hsp_query-to>
      <Hsp_hit-from>826</Hsp_hit-from>
      <Hsp_hit-to>868</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>15</Hsp_identity>
      <Hsp_positive>28</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>43</Hsp_align-len>
      <Hsp_qseq>RLHVCDECGKGFSDTSNLKKHVRT-HTGERPYKCGVCAKGFSQ</Hsp_qseq>
      <Hsp_hseq>KIYICRECNRQFSSGHHLTRHKKSVHSGEKPHSCPRCGKRFKR</Hsp_hseq>
      <Hsp_midline>++++C EC + FS   +L +H ++ H+GE+P+ C  C K F +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YER169W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:523369:525759:1 gene:YER169W transcript:YER169W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RPH1 description:JmjC domain-containing histone demethylase; targets tri- and dimethylated H3K36; associates with actively transcribed regions and promotes elongation; repressor of autophagy-related genes in nutrient-replete conditions; damage-responsive repressor of PHR1; phosphorylated by the Rad53p-dependent DNA damage checkpoint pathway and by a Rim1p-mediated event during starvation; target of stress-induced hormesis; RPH1 has a paralog, GIS1, that arose from the whole genome duplication [Source:SGD;Acc:S000000971]</Hit_def>
  <Hit_accession>YER169W</Hit_accession>
  <Hit_len>796</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>42.743</Hsp_bit-score>
      <Hsp_score>99</Hsp_score>
      <Hsp_evalue>9.94398e-06</Hsp_evalue>
      <Hsp_query-from>76</Hsp_query-from>
      <Hsp_query-to>279</Hsp_query-to>
      <Hsp_hit-from>707</Hsp_hit-from>
      <Hsp_hit-to>772</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>22</Hsp_identity>
      <Hsp_positive>38</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>70</Hsp_align-len>
      <Hsp_qseq>RLHVCDECGKGFSDTSNLKKHVRT-HTGERPYKCGVCAKGFSQASTMRIHQKMH-SLETPVPGEEVQVEA</Hsp_qseq>
      <Hsp_hseq>KIYICKECQRKFSSGHHLTRHKKSVHSGEKPHSCPKCGKRFKR----RDHVLQHLNKKIPCISNETTVDA</Hsp_hseq>
      <Hsp_midline>++++C EC + FS   +L +H ++ H+GE+P+ C  C K F +    R H   H + + P    E  V+A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>82</Statistics_hsp-len>
      <Statistics_eff-space>185083626</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0063515-RA transcript Note:&quot;Similar to MXRA5 Matrix-remodeling-associated protein 5 (Homo sapiens)&quot; offset:0 AED:0.32 eAED:0.32 QI:0|0|0|0.58|0.90|0.83|12|0|3244</Iteration_query-def>
  <Iteration_query-len>9735</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>108</Statistics_hsp-len>
      <Statistics_eff-space>6905374579</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0049036-RA transcript Note:&quot;Similar to gjc1 Gap junction gamma-1 protein (Danio rerio)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|-1|0|0|-1|0|1|0|243</Iteration_query-def>
  <Iteration_query-len>732</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>87</Statistics_hsp-len>
      <Statistics_eff-space>367359119</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0048678-RA transcript Note:&quot;Similar to Pkp4 Plakophilin-4 (Mus musculus)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.66|0.5|4|257|239</Iteration_query-def>
  <Iteration_query-len>977</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>545215745</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0063433-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.42 eAED:0.78 QI:0|0|0|0.75|1|1|4|0|136</Iteration_query-def>
  <Iteration_query-len>411</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>80</Statistics_hsp-len>
      <Statistics_eff-space>136005819</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0063280-RA transcript Note:&quot;Similar to UBE2L3 Ubiquitin-conjugating enzyme E2 L3 (Pongo abelii)&quot; offset:33 AED:0.02 eAED:0.02 QI:33|0.5|0.6|0.8|0.25|0.6|5|3746|154</Iteration_query-def>
  <Iteration_query-len>4244</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDR059C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:569234:569770:-1 gene:YDR059C transcript:YDR059C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBC5 description:Ubiquitin-conjugating enzyme; mediates selective degradation of short-lived, abnormal, or excess proteins, including histone H3; central component of the cellular stress response; expression is heat inducible; protein abundance increases in response to DNA replication stress; UBC5 has a paralog, UBC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002466]</Hit_def>
  <Hit_accession>YDR059C</Hit_accession>
  <Hit_len>148</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>100.138</Hsp_bit-score>
      <Hsp_score>248</Hsp_score>
      <Hsp_evalue>8.41655e-25</Hsp_evalue>
      <Hsp_query-from>34</Hsp_query-from>
      <Hsp_query-to>474</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>147</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>148</Hsp_align-len>
      <Hsp_qseq>MAATRRLFKELTDIRLSNCKNFQNIIVDETNLLFWQGLIV-PEKAPYDKGAFKIEISFPPEYPFKPPKINFRTKIYHPNVDEKGQSLIDLVNXXXXXXXXXXXXIQSLIDLVNHPEPEHPLRADLAEEFSKDQKKFLKNAEEFTKKHG</Hsp_qseq>
      <Hsp_hseq>MSSSKRIAKELSDLGRDPPASCSAGPVGD-DLYHWQASIMGPSDSPYAGGVFFLSIHFPTDYPFKPPKVNFTTKIYHPNINSSGNICLDILKDQWSPALTLSKVLLSICSLLTDANPDDPLVPEIAQIYKTDKAKYEATAKEWTKKYA</Hsp_hseq>
      <Hsp_midline>M++++R+ KEL+D+      +     V + +L  WQ  I+ P  +PY  G F + I FP +YPFKPPK+NF TKIYHPN++  G   +D++            ++ S+  L+    P+ PL  ++A+ +  D+ K+   A+E+TKK+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YBR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:406628:407169:-1 gene:YBR082C transcript:YBR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBC4 description:Ubiquitin-conjugating enzyme (E2); key E2 partner with Ubc1p for the anaphase-promoting complex (APC); mediates degradation of abnormal or excess proteins, including calmodulin and histone H3; regulates levels of DNA Polymerase-{alpha} to promote efficient and accurate DNA replication; interacts with many SCF ubiquitin protein ligases; component of the cellular stress response; UBC4 has a paralog, UBC5, that arose from the whole genome duplication [Source:SGD;Acc:S000000286]</Hit_def>
  <Hit_accession>YBR082C</Hit_accession>
  <Hit_len>148</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>96.6709</Hsp_bit-score>
      <Hsp_score>239</Hsp_score>
      <Hsp_evalue>1.22898e-23</Hsp_evalue>
      <Hsp_query-from>34</Hsp_query-from>
      <Hsp_query-to>474</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>147</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>148</Hsp_align-len>
      <Hsp_qseq>MAATRRLFKELTDIRLSNCKNFQNIIVDETNLLFWQGLIV-PEKAPYDKGAFKIEISFPPEYPFKPPKINFRTKIYHPNVDEKGQSLIDLVNXXXXXXXXXXXXIQSLIDLVNHPEPEHPLRADLAEEFSKDQKKFLKNAEEFTKKHG</Hsp_qseq>
      <Hsp_hseq>MSSSKRIAKELSDLERDPPTSCSAGPVGD-DLYHWQASIMGPADSPYAGGVFFLSIHFPTDYPFKPPKISFTTKIYHPNINANGNICLDILKDQWSPALTLSKVLLSICSLLTDANPDDPLVPEIAHIYKTDRPKYEATAREWTKKYA</Hsp_hseq>
      <Hsp_midline>M++++R+ KEL+D+      +     V + +L  WQ  I+ P  +PY  G F + I FP +YPFKPPKI+F TKIYHPN++  G   +D++            ++ S+  L+    P+ PL  ++A  +  D+ K+   A E+TKK+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YDR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:629876:630605:1 gene:YDR092W transcript:YDR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBC13 description:E2 ubiquitin-conjugating enzyme; involved in the error-free DNA postreplication repair pathway; interacts with Mms2p to assemble ubiquitin chains at the Ub Lys-63 residue; DNA damage triggers redistribution from the cytoplasm to the nucleus [Source:SGD;Acc:S000002499]</Hit_def>
  <Hit_accession>YDR092W</Hit_accession>
  <Hit_len>153</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.5001</Hsp_bit-score>
      <Hsp_score>210</Hsp_score>
      <Hsp_evalue>9.93584e-20</Hsp_evalue>
      <Hsp_query-from>118</Hsp_query-from>
      <Hsp_query-to>486</Hsp_query-to>
      <Hsp_hit-from>29</Hsp_hit-from>
      <Hsp_hit-to>152</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>124</Hsp_align-len>
      <Hsp_qseq>ETNLLFWQGLIV-PEKAPYDKGAFKIEISFPPEYPFKPPKINFRTKIYHPNVDEKGQSLIDLVNXXXXXXXXXXXXIQSLIDLVNHPEPEHPLRADLAEEFSKDQKKFLKNAEEFTKKHGEKRP</Hsp_qseq>
      <Hsp_hseq>DDNLRYFQVTIEGPEQSPYEDGIFELELYLPDDYPMEAPKVRFLTKIYHPNIDRLGRICLDVLKTNWSPALQIRTVLLSIQALLASPNPNDPLANDVAEDWIKNEQGAKAKAREWTKLYAKKKP</Hsp_hseq>
      <Hsp_midline>+ NL ++Q  I  PE++PY+ G F++E+  P +YP + PK+ F TKIYHPN+D  G+  +D++            ++ S+  L+  P P  PL  D+AE++ K+++     A E+TK + +K+P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YOR339C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:958362:958832:-1 gene:YOR339C transcript:YOR339C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBC11 description:Ubiquitin-conjugating enzyme; most similar in sequence to Xenopus ubiquitin-conjugating enzyme E2-C, but not a true functional homolog of this E2; unlike E2-C, not required for the degradation of mitotic cyclin Clb2 [Source:SGD;Acc:S000005866]</Hit_def>
  <Hit_accession>YOR339C</Hit_accession>
  <Hit_len>156</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.5741</Hsp_bit-score>
      <Hsp_score>205</Hsp_score>
      <Hsp_evalue>6.06602e-19</Hsp_evalue>
      <Hsp_query-from>37</Hsp_query-from>
      <Hsp_query-to>444</Hsp_query-to>
      <Hsp_hit-from>8</Hsp_hit-from>
      <Hsp_hit-to>144</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>137</Hsp_align-len>
      <Hsp_qseq>AATRRLFKELTDIRLSNCKNFQNIIVDETNLLFWQGLIV-PEKAPYDKGAFKIEISFPPEYPFKPPKINFRTKIYHPNVDEKGQSLIDLVNXXXXXXXXXXXXIQSLIDLVNHPEPEHPLRADLAEEFSKDQKKFLK</Hsp_qseq>
      <Hsp_hseq>CVTKRLQNELLQLLSSTTESISAFPVDDNDLTYWVGYITGPKDTPYSGLKFKVSLKFPQNYPFHPPMIKFLSPMWHPNVDKSGNICLDILKEKWSAVYNVETILLSLQSLLGEPNNRSPLNAVAAELWDADMEEYRK</Hsp_hseq>
      <Hsp_midline>  T+RL  EL  +  S  ++     VD+ +L +W G I  P+  PY    FK+ + FP  YPF PP I F + ++HPNVD+ G   +D++            ++ SL  L+  P    PL A  AE +  D +++ K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YDR177W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:816878:817525:1 gene:YDR177W transcript:YDR177W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBC1 description:Ubiquitin-conjugating enzyme; key E2 partner with Ubc4p for the anaphase-promoting complex (APC); mediates selective degradation of short-lived and abnormal proteins; plays a role in vesicle biogenesis and ER-associated protein degradation (ERAD); component of the cellular stress response; protein abundance increases in response to DNA replication stress key E2 partner with Ubc4p for the anaphase-promoting complex (APC) [Source:SGD;Acc:S000002584]</Hit_def>
  <Hit_accession>YDR177W</Hit_accession>
  <Hit_len>215</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>84.3445</Hsp_bit-score>
      <Hsp_score>207</Hsp_score>
      <Hsp_evalue>1.27521e-18</Hsp_evalue>
      <Hsp_query-from>34</Hsp_query-from>
      <Hsp_query-to>480</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>151</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>151</Hsp_align-len>
      <Hsp_qseq>MAATRRLFKELTDIRLSNCKNFQNIIVDETNLLFWQGLIV-PEKAPYDKGAFKIEISFPPEYPFKPPKINFRTKIYHPNVDE-KGQSLIDLVNXXXXXXXXXXXXIQSLIDLVNHPEPEHPLRADLAEEFSKDQKKFLKNAEEFTKKHGEK</Hsp_qseq>
      <Hsp_hseq>MSRAKRIMKEIQAVKDDPAAHITLEFVSESDIHHLKGTFLGPPGTPYEGGKFVVDIEVPMEYPFKPPKMQFDTKVYHPNISSVTGAICLDILKNAWSPVITLKSALISLQALLQSPEPNDPQDAEVAQHYLRDRESFNKTAALWTRLYASE</Hsp_hseq>
      <Hsp_midline>M+  +R+ KE+  ++     +     V E+++   +G  + P   PY+ G F ++I  P EYPFKPPK+ F TK+YHPN+    G   +D++ +           + SL  L+  PEP  P  A++A+ + +D++ F K A  +T+ +  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YGL058W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:393986:394504:1 gene:YGL058W transcript:YGL058W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD6 description:Ubiquitin-conjugating enzyme (E2); involved in postreplication repair as a heterodimer with Rad18p, regulation of K63 polyubiquitination in response to oxidative stress, DSBR and checkpoint control as a heterodimer with Bre1p, ubiquitin-mediated N-end rule protein degradation as a heterodimer with Ubr1p, ERAD with Ubr1p in the absence of canonical ER membrane ligases, and Rpn4p turnover as part of proteasome homeostasis, in complex with Ubr2p and Mub1p [Source:SGD;Acc:S000003026]</Hit_def>
  <Hit_accession>YGL058W</Hit_accession>
  <Hit_len>172</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.7886</Hsp_bit-score>
      <Hsp_score>177</Hsp_score>
      <Hsp_evalue>5.06627e-15</Hsp_evalue>
      <Hsp_query-from>124</Hsp_query-from>
      <Hsp_query-to>477</Hsp_query-to>
      <Hsp_hit-from>32</Hsp_hit-from>
      <Hsp_hit-to>150</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>119</Hsp_align-len>
      <Hsp_qseq>NLLFWQGLIV-PEKAPYDKGAFKIEISFPPEYPFKPPKINFRTKIYHPNVDEKGQSLIDLVNXXXXXXXXXXXXIQSLIDLVNHPEPEHPLRADLAEEFSKDQKKFLKNAEEFTKKHGE</Hsp_qseq>
      <Hsp_hseq>NVMVWNAMIIGPADTPYEDGTFRLLLEFDEEYPNKPPHVKFLSEMFHPNVYANGEICLDILQNRWTPTYDVASILTSIQSLFNDPNPASPANVEAATLFKDHKSQYVKRVKETVEKSWE</Hsp_hseq>
      <Hsp_midline>N++ W  +I+ P   PY+ G F++ + F  EYP KPP + F ++++HPNV   G+  +D++ +          ++ S+  L N P P  P   + A  F   + +++K  +E  +K  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YEL012W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:131772:132551:1 gene:YEL012W transcript:YEL012W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBC8 description:Ubiquitin-conjugating enzyme that regulates gluconeogenesis; negatively regulates gluconeogenesis by mediating the glucose-induced ubiquitination of fructose-1,6-bisphosphatase (FBPase); cytoplasmic enzyme that catalyzes the ubiquitination of histones in vitro [Source:SGD;Acc:S000000738]</Hit_def>
  <Hit_accession>YEL012W</Hit_accession>
  <Hit_len>218</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>1.23794e-11</Hsp_evalue>
      <Hsp_query-from>34</Hsp_query-from>
      <Hsp_query-to>492</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>153</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>155</Hsp_align-len>
      <Hsp_qseq>MAATRRLFKELTDIRLSNCKNFQNIIVDETNLLFWQGLIVPEKAPYDKGAFKIEISFPPEYPFKPPKINFRTKIYHPNVD-EKGQSLIDLVNXXXXXXXXXXXXIQSLI-DLVNHPEPEHPLRADLAEEFSKDQKKFLKNAEEFTKKHGEKRPTQ</Hsp_qseq>
      <Hsp_hseq>MSSSKRRIE--TDVMKLLMSDHQVDLINDSMQEFHVKFLGPKDTPYENGVWRLHVELPDNYPYKSPSIGFVNKIFHPNIDIASGSICLDVINSTWSPLYDLINIVEWMIPGLLKEPNGSDPLNNEAATLQLRDKKLYEEKIKEYIDKYATKEKYQ</Hsp_hseq>
      <Hsp_midline>M++++R  +  TD+      + Q  +++++   F    + P+  PY+ G +++ +  P  YP+K P I F  KI+HPN+D   G   +D++N           +++ +I  L+  P    PL  + A    +D+K + +  +E+  K+  K   Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YDR054C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:561440:562327:-1 gene:YDR054C transcript:YDR054C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC34 description:Ubiquitin-conjugating enzyme (E2); catalytic subunit of SCF ubiquitin-protein ligase complex (together with Skp1p, Rbx1p, Cdc53p, and an F-box protein) that regulates cell cycle progression by targeting key substrates for degradation; protein abundance increases in response to DNA replication stress; human CDC34 functionally complements the thermosensitivity of the cdc34-2 mutant [Source:SGD;Acc:S000002461]</Hit_def>
  <Hit_accession>YDR054C</Hit_accession>
  <Hit_len>295</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>1.21487e-10</Hsp_evalue>
      <Hsp_query-from>13</Hsp_query-from>
      <Hsp_query-to>438</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>156</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>156</Hsp_align-len>
      <Hsp_qseq>GSRRTTKMAATRRLFKELTDIRLSNCKNFQNIIVDETNLLFWQ--GLIVPEKAPYDKGAFKIEISFPPEYPFKPPKINFRTKIYHPNVDEKGQSLIDLVNXXX------------XXXXXXXXXIQSLIDLVNHPEPEHPLRADLAEEFSKDQKKF</Hsp_qseq>
      <Hsp_hseq>SSRKSTASSLLLRQYRELTDPKKA-IPSFHIELEDDSNIFTWNIGVMVLNEDSIYHGGFFKAQMRFPEDFPFSPPQFRFTPAIYHPNVYRDGRLCISILHQSGDPMTDEPDAETWSPVQTVESVLISIVSLLEDPNINSPANVDAAVDYRKNPEQY</Hsp_hseq>
      <Hsp_midline> SR++T  +   R ++ELTD + +   +F   + D++N+  W    +++ E + Y  G FK ++ FP ++PF PP+  F   IYHPNV   G+  I +++                       ++ S++ L+  P    P   D A ++ K+ +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YMR022W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:318680:319177:1 gene:YMR022W transcript:YMR022W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBC7 description:Ubiquitin conjugating enzyme; involved in the ER-associated protein degradation (ERAD) pathway and in the inner nuclear membrane-associated degradation (INMAD) pathway; requires Cue1p for recruitment to the ER membrane; proposed to be involved in chromatin assembly [Source:SGD;Acc:S000004624]</Hit_def>
  <Hit_accession>YMR022W</Hit_accession>
  <Hit_len>165</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>8.005e-10</Hsp_evalue>
      <Hsp_query-from>37</Hsp_query-from>
      <Hsp_query-to>306</Hsp_query-to>
      <Hsp_hit-from>4</Hsp_hit-from>
      <Hsp_hit-to>94</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>43</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>91</Hsp_align-len>
      <Hsp_qseq>AATRRLFKELTDIRLSNCKNFQNIIVDETNLLFWQGLIV-PEKAPYDKGAFKIEISFPPEYPFKPPKINFRTKIYHPNVDEKGQSLIDLVN</Hsp_qseq>
      <Hsp_hseq>TAQKRLLKELQQLIKDSPPGIVAGPKSENNIFIWDCLIQGPPDTPYADGVFNAKLEFPKDYPLSPPKLTFTPSILHPNIYPNGEVCISILH</Hsp_hseq>
      <Hsp_midline> A +RL KEL  +   +          E N+  W  LI  P   PY  G F  ++ FP +YP  PPK+ F   I HPN+   G+  I +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YLR306W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:744151:744851:1 gene:YLR306W transcript:YLR306W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBC12 description:Enzyme that mediates the conjugation of Rub1p; a ubiquitin-like protein, to other proteins; related to E2 ubiquitin-conjugating enzymes [Source:SGD;Acc:S000004297]</Hit_def>
  <Hit_accession>YLR306W</Hit_accession>
  <Hit_len>188</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>4.71125e-09</Hsp_evalue>
      <Hsp_query-from>145</Hsp_query-from>
      <Hsp_query-to>438</Hsp_query-to>
      <Hsp_hit-from>67</Hsp_hit-from>
      <Hsp_hit-to>164</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>98</Hsp_align-len>
      <Hsp_qseq>LIVPEKAPYDKGAFKIEISFPPEYPFKPPKINFRTKIYHPNVDEKGQSLIDLVNXXXXXXXXXXXXIQSLIDLVNHPEPEHPLRADLAEEFSKDQKKF</Hsp_qseq>
      <Hsp_hseq>IVRPDEGYYNYGSINFNLDFNEVYPIEPPKVVCLKKIFHPNIDLKGNVCLNILREDWSPALDLQSIITGLLFLFLEPNPNDPLNKDAAKLLCEGEKEF</Hsp_hseq>
      <Hsp_midline>++ P++  Y+ G+    + F   YP +PPK+    KI+HPN+D KG   ++++            +I  L+ L   P P  PL  D A+   + +K+F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YDL064W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:337487:338070:1 gene:YDL064W transcript:YDL064W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBC9 description:SUMO-conjugating enzyme involved in the Smt3p conjugation pathway; nuclear protein required for S- and M-phase cyclin degradation and mitotic control; involved in proteolysis mediated by the anaphase-promoting complex cyclosome (APCC) [Source:SGD;Acc:S000002222]</Hit_def>
  <Hit_accession>YDL064W</Hit_accession>
  <Hit_len>157</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>9.00791e-09</Hsp_evalue>
      <Hsp_query-from>124</Hsp_query-from>
      <Hsp_query-to>465</Hsp_query-to>
      <Hsp_hit-from>37</Hsp_hit-from>
      <Hsp_hit-to>157</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>121</Hsp_align-len>
      <Hsp_qseq>NLLFWQ-GLIVPEKAPYDKGAFKIEISFPPEYPFKPPKINFRTKIYHPNVDEKGQSLIDLVNXXXXX--XXXXXXXIQSLIDLVNHPEPEHPLRADLAEEFSKDQ----KKFLKNAEEFTK</Hsp_qseq>
      <Hsp_hseq>DLQKWEAGIPGKEGTNWAGGVYPITVEYPNEYPSKPPKVKFPAGFYHPNVYPSGTICLSILNEDQDWRPAITLKQIVLGVQDLLDSPNPNSPAQEPAWRSFSRNKAEYDKKVLLQAKQYSK</Hsp_hseq>
      <Hsp_midline>+L  W+ G+   E   +  G + I + +P EYP KPPK+ F    YHPNV   G   + ++N  +          ++  + DL++ P P  P +      FS+++    KK L  A++++K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YGR133W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:756896:757447:1 gene:YGR133W transcript:YGR133W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PEX4 description:Peroxisomal ubiquitin conjugating enzyme; required for peroxisomal matrix protein import and peroxisome biogenesis [Source:SGD;Acc:S000003365]</Hit_def>
  <Hit_accession>YGR133W</Hit_accession>
  <Hit_len>183</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.3654</Hsp_bit-score>
      <Hsp_score>111</Hsp_score>
      <Hsp_evalue>3.50318e-06</Hsp_evalue>
      <Hsp_query-from>112</Hsp_query-from>
      <Hsp_query-to>270</Hsp_query-to>
      <Hsp_hit-from>53</Hsp_hit-from>
      <Hsp_hit-to>107</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>32</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>55</Hsp_align-len>
      <Hsp_qseq>VDETNLLFWQGLIV-PEKAPYDKGAFKIEISFPPEYPFKPPKINF-RTKIYHPNV</Hsp_qseq>
      <Hsp_hseq>IDETDLSKWEAIISGPSDTPYENHQFRILIEVPSSYPMNPPKISFMQNNILHCNV</Hsp_hseq>
      <Hsp_midline>+DET+L  W+ +I  P   PY+   F+I I  P  YP  PPKI+F +  I H NV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>102</Statistics_hsp-len>
      <Statistics_eff-space>2940017504</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0063281-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.51 eAED:0.74 QI:0|0|0|0.28|1|1|7|0|970</Iteration_query-def>
  <Iteration_query-len>2913</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>1971301624</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0063283-RA transcript Note:&quot;Similar to Phkg1 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (Rattus norvegicus)&quot; offset:0 AED:0.17 eAED:0.25 QI:0|-1|0|1|-1|1|1|0|107</Iteration_query-def>
  <Iteration_query-len>324</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>1.75585e-12</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>138</Hsp_query-to>
      <Hsp_hit-from>123</Hsp_hit-from>
      <Hsp_hit-to>167</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>34</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>45</Hsp_align-len>
      <Hsp_qseq>RAVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFACRL</Hsp_qseq>
      <Hsp_hseq>QQLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGLASQF</Hsp_hseq>
      <Hsp_midline>+ ++  ++YLH E GV HRD+KPENILLD  G++KL+DFG A + </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>6.03346e-10</Hsp_evalue>
      <Hsp_query-from>10</Hsp_query-from>
      <Hsp_query-to>156</Hsp_query-to>
      <Hsp_hit-from>233</Hsp_hit-from>
      <Hsp_hit-to>286</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>26</Hsp_identity>
      <Hsp_positive>37</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>55</Hsp_align-len>
      <Hsp_qseq>VLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFACRLP------APGQP</Hsp_qseq>
      <Hsp_hseq>IIDAVDSLHN-IGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKP</Hsp_hseq>
      <Hsp_midline>+++ V  LH+ +G++HRD+KPENILLD    +KL+DFG A  LP      A G+P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>6.42686e-10</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>141</Hsp_query-to>
      <Hsp_hit-from>198</Hsp_hit-from>
      <Hsp_hit-to>236</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>31</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>40</Hsp_align-len>
      <Hsp_qseq>VHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFACRLP</Hsp_qseq>
      <Hsp_hseq>LEYLHSK-DIIYRDLKPENILLDKNGHIKITDFGFAKYVP</Hsp_hseq>
      <Hsp_midline>+ YLH +  +++RDLKPENILLD  G IK++DFGFA  +P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>6.42968e-10</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>141</Hsp_query-to>
      <Hsp_hit-from>199</Hsp_hit-from>
      <Hsp_hit-to>237</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>31</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>40</Hsp_align-len>
      <Hsp_qseq>VHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFACRLP</Hsp_qseq>
      <Hsp_hseq>LEYLHSK-DIIYRDLKPENILLDKNGHIKITDFGFAKYVP</Hsp_hseq>
      <Hsp_midline>+ YLH +  +++RDLKPENILLD  G IK++DFGFA  +P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>1.05915e-09</Hsp_evalue>
      <Hsp_query-from>10</Hsp_query-from>
      <Hsp_query-to>150</Hsp_query-to>
      <Hsp_hit-from>1374</Hsp_hit-from>
      <Hsp_hit-to>1419</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>33</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>47</Hsp_align-len>
      <Hsp_qseq>VLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFACRLPAPG</Hsp_qseq>
      <Hsp_hseq>LLEGLAYLH-ESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNG</Hsp_hseq>
      <Hsp_midline>+LE + YLH E G+VHRD+KPENILLD  G IK  DFG A ++   G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>1.13743e-09</Hsp_evalue>
      <Hsp_query-from>10</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>287</Hsp_hit-from>
      <Hsp_hit-to>325</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>22</Hsp_identity>
      <Hsp_positive>30</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>40</Hsp_align-len>
      <Hsp_qseq>VLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>IIDAIDYLHSN-GIIHRDIKPENILLDGEMKIKLTDFGTA</Hsp_hseq>
      <Hsp_midline>+++ + YLH   G++HRD+KPENILLD    IKL+DFG A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>1.19584e-09</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>288</Hsp_hit-from>
      <Hsp_hit-to>322</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>29</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>36</Hsp_align-len>
      <Hsp_qseq>VHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>VNALHD-LGYTHRDLKPENFLIDAKGHIKLTDFGLA</Hsp_hseq>
      <Hsp_midline>V+ LHD +G  HRDLKPEN L+D++G IKL+DFG A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>1.91416e-09</Hsp_evalue>
      <Hsp_query-from>10</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>177</Hsp_hit-from>
      <Hsp_hit-to>215</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>30</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>40</Hsp_align-len>
      <Hsp_qseq>VLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>VILALEYLHAH-NIIYRDLKPENILLDRNGHIKITDFGFA</Hsp_hseq>
      <Hsp_midline>V+  + YLH    +++RDLKPENILLD  G IK++DFGFA</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>2.45634e-09</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>138</Hsp_query-to>
      <Hsp_hit-from>721</Hsp_hit-from>
      <Hsp_hit-to>764</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>32</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>45</Hsp_align-len>
      <Hsp_qseq>RAVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFACRL</Hsp_qseq>
      <Hsp_hseq>RETLSGLEFLHSK-GVLHRDIKSDNILLSMEGDIKLTDFGFCAQI</Hsp_hseq>
      <Hsp_midline>R  L  + +LH + GV+HRD+K +NILL   GDIKL+DFGF  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>2.556e-09</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>138</Hsp_hit-from>
      <Hsp_hit-to>178</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>32</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>42</Hsp_align-len>
      <Hsp_qseq>RAVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>RQIIIGVSYCH-ALGIVHRDLKPENLLLDHKYNIKIADFGMA</Hsp_hseq>
      <Hsp_midline>R ++  V Y H  +G+VHRDLKPEN+LLD + +IK++DFG A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>2.7283e-09</Hsp_evalue>
      <Hsp_query-from>10</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>1142</Hsp_hit-from>
      <Hsp_hit-to>1180</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>26</Hsp_identity>
      <Hsp_positive>30</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>40</Hsp_align-len>
      <Hsp_qseq>VLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>LLEGLAYLH-QSGVVHRDIKPENILLDFNGIIKYVDFGTA</Hsp_hseq>
      <Hsp_midline>+LE + YLH + GVVHRD+KPENILLD  G IK  DFG A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>2.85805e-09</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>325</Hsp_hit-from>
      <Hsp_hit-to>364</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>32</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>41</Hsp_align-len>
      <Hsp_qseq>AVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>SVLRGLSYLH-ERKVIHRDIKPQNILLNEKGEIKLCDFGVS</Hsp_hseq>
      <Hsp_midline>+VL  + YLH E  V+HRD+KP+NILL+ +G+IKL DFG +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>2.9732e-09</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>817</Hsp_hit-from>
      <Hsp_hit-to>857</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>20</Hsp_identity>
      <Hsp_positive>30</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>42</Hsp_align-len>
      <Hsp_qseq>RAVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>RQILEALSYIHSQ-GIIHRDLKPMNIFIDESRNVKIGDFGLA</Hsp_hseq>
      <Hsp_midline>R +LE + Y+H + G++HRDLKP NI +D   ++K+ DFG A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>4.08361e-09</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>138</Hsp_query-to>
      <Hsp_hit-from>674</Hsp_hit-from>
      <Hsp_hit-to>718</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>20</Hsp_identity>
      <Hsp_positive>34</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>46</Hsp_align-len>
      <Hsp_qseq>MRAVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFACRL</Hsp_qseq>
      <Hsp_hseq>VRETCQGLKFLHDK-HIIHRDIKSDNVLLDTRARVKITDFGFCARL</Hsp_hseq>
      <Hsp_midline>+R   + + +LHD+  ++HRD+K +N+LLD+R  +K++DFGF  RL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>4.46607e-09</Hsp_evalue>
      <Hsp_query-from>13</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>463</Hsp_hit-from>
      <Hsp_hit-to>497</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>22</Hsp_identity>
      <Hsp_positive>29</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>39</Hsp_align-len>
      <Hsp_qseq>LEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>IETIHKL----GFIHRDIKPDNILIDIRGHIKLSDFGLS</Hsp_hseq>
      <Hsp_midline>+E +H L    G +HRD+KP+NIL+D RG IKLSDFG +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>4.46975e-09</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>134</Hsp_hit-from>
      <Hsp_hit-to>174</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>32</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>42</Hsp_align-len>
      <Hsp_qseq>RAVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>RQIIIGISYCH-ALGIVHRDLKPENLLLDSFYNIKIADFGMA</Hsp_hseq>
      <Hsp_midline>R ++  + Y H  +G+VHRDLKPEN+LLDS  +IK++DFG A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YPR111W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:747306:749000:1 gene:YPR111W transcript:YPR111W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF20 description:Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006315]</Hit_def>
  <Hit_accession>YPR111W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>4.84232e-09</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>280</Hsp_hit-from>
      <Hsp_hit-to>314</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>28</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>36</Hsp_align-len>
      <Hsp_qseq>VHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>VNALH-ELGYTHRDLKPENFLIDATGHIKLTDFGLA</Hsp_hseq>
      <Hsp_midline>V+ LH E+G  HRDLKPEN L+D+ G IKL+DFG A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>7.41386e-09</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>332</Hsp_hit-from>
      <Hsp_hit-to>371</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>30</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>41</Hsp_align-len>
      <Hsp_qseq>AVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>AVLRGLSYLH-EKKVIHRDIKPQNILLNENGQVKLCDFGVS</Hsp_hseq>
      <Hsp_midline>AVL  + YLH E  V+HRD+KP+NILL+  G +KL DFG +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>8.33996e-09</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>168</Hsp_hit-from>
      <Hsp_hit-to>211</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>32</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>45</Hsp_align-len>
      <Hsp_qseq>RAVLEVV---HYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>KVVLDVVSGLEYLHSQ-GITHRDIKPSNLLISSNGTVKISDFGVA</Hsp_hseq>
      <Hsp_midline>+ VL+VV    YLH + G+ HRD+KP N+L+ S G +K+SDFG A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>1.29382e-08</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>162</Hsp_query-to>
      <Hsp_hit-from>114</Hsp_hit-from>
      <Hsp_hit-to>166</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>22</Hsp_identity>
      <Hsp_positive>34</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>54</Hsp_align-len>
      <Hsp_qseq>MRAVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFACRLPAPGQPQL</Hsp_qseq>
      <Hsp_hseq>IKQLCSAISFAH-SLGIAHRDIKPENILLTINGDIKLADWGHAIQSPKSNDFQI</Hsp_hseq>
      <Hsp_midline>++ +   + + H  +G+ HRD+KPENILL   GDIKL+D+G A + P     Q+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>2.18648e-08</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>957</Hsp_hit-from>
      <Hsp_hit-to>997</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>32</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>42</Hsp_align-len>
      <Hsp_qseq>RAVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>KQVVASIKHLHDQ-GIVHRDIKDENVIVDSHGFVKLIDFGSA</Hsp_hseq>
      <Hsp_midline>+ V+  + +LHD+ G+VHRD+K EN+++DS G +KL DFG A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>2.50297e-08</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>138</Hsp_query-to>
      <Hsp_hit-from>313</Hsp_hit-from>
      <Hsp_hit-to>356</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>19</Hsp_identity>
      <Hsp_positive>32</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>44</Hsp_align-len>
      <Hsp_qseq>AVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFACRL</Hsp_qseq>
      <Hsp_hseq>GVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKL</Hsp_hseq>
      <Hsp_midline> VL  + +L+ +  ++HRD+KP N+L++S+G IKL DFG + +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>2.83757e-08</Hsp_evalue>
      <Hsp_query-from>10</Hsp_query-from>
      <Hsp_query-to>171</Hsp_query-to>
      <Hsp_hit-from>122</Hsp_hit-from>
      <Hsp_hit-to>170</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>35</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>54</Hsp_align-len>
      <Hsp_qseq>VLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFACRLPAPGQPQLRGE</Hsp_qseq>
      <Hsp_hseq>LIDALEFIHSH-GIIHRDLKPENVLLDRDGRLMITDFGAAATI----DPSLSGD</Hsp_hseq>
      <Hsp_midline>+++ + ++H   G++HRDLKPEN+LLD  G + ++DFG A  +     P L G+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>2.90387e-08</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>141</Hsp_query-to>
      <Hsp_hit-from>566</Hsp_hit-from>
      <Hsp_hit-to>605</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>18</Hsp_identity>
      <Hsp_positive>27</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>40</Hsp_align-len>
      <Hsp_qseq>VHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFACRLP</Hsp_qseq>
      <Hsp_hseq>LRFIHDSCHIVHLDLKPANVMITFEGNLKLGDFGMATHLP</Hsp_hseq>
      <Hsp_midline>+ ++HD   +VH DLKP N+++   G++KL DFG A  LP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>4.12206e-08</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>526</Hsp_hit-from>
      <Hsp_hit-to>560</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>28</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>36</Hsp_align-len>
      <Hsp_qseq>VHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>LEHLHDN-DIVYRDLKPENILLDANGNIALCDFGLS</Hsp_hseq>
      <Hsp_midline>+ +LHD   +V+RDLKPENILLD+ G+I L DFG +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>4.71059e-08</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>1212</Hsp_hit-from>
      <Hsp_hit-to>1252</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>20</Hsp_identity>
      <Hsp_positive>33</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>42</Hsp_align-len>
      <Hsp_qseq>RAVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>KQVVAGIKHLHDQ-GIVHRDIKDENVIVDSKGFVKIIDFGSA</Hsp_hseq>
      <Hsp_midline>+ V+  + +LHD+ G+VHRD+K EN+++DS+G +K+ DFG A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.595</Hsp_bit-score>
      <Hsp_score>109</Hsp_score>
      <Hsp_evalue>8.33876e-08</Hsp_evalue>
      <Hsp_query-from>10</Hsp_query-from>
      <Hsp_query-to>168</Hsp_query-to>
      <Hsp_hit-from>128</Hsp_hit-from>
      <Hsp_hit-to>175</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>34</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>53</Hsp_align-len>
      <Hsp_qseq>VLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFACRLPAPGQPQLRG</Hsp_qseq>
      <Hsp_hseq>ILRGLKYVH-SAGVIHRDLKPSNILINENCDLKICDFGLA-RIQ---DPQMTG</Hsp_hseq>
      <Hsp_midline>+L  + Y+H   GV+HRDLKP NIL++   D+K+ DFG A R+     PQ+ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.9802</Hsp_bit-score>
      <Hsp_score>110</Hsp_score>
      <Hsp_evalue>8.57181e-08</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>126</Hsp_query-to>
      <Hsp_hit-from>163</Hsp_hit-from>
      <Hsp_hit-to>196</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>20</Hsp_identity>
      <Hsp_positive>28</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>35</Hsp_align-len>
      <Hsp_qseq>VHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGF</Hsp_qseq>
      <Hsp_hseq>VHYIHSK-GLVHRDLKLENLLLDKNENLVITDFGF</Hsp_hseq>
      <Hsp_midline>VHY+H + G+VHRDLK EN+LLD   ++ ++DFGF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.595</Hsp_bit-score>
      <Hsp_score>109</Hsp_score>
      <Hsp_evalue>1.09346e-07</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>123</Hsp_query-to>
      <Hsp_hit-from>431</Hsp_hit-from>
      <Hsp_hit-to>469</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>30</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>40</Hsp_align-len>
      <Hsp_qseq>RAVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFG</Hsp_qseq>
      <Hsp_hseq>KQLIRGVVYMH-EMGVCHRDLKPENLLLTHDGVLKITDFG</Hsp_hseq>
      <Hsp_midline>+ ++  V Y+H E+GV HRDLKPEN+LL   G +K++DFG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YJL165C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:106894:109461:-1 gene:YJL165C transcript:YJL165C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HAL5 description:Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters; HAL5 has a paralog, KKQ8, that arose from the whole genome duplication [Source:SGD;Acc:S000003701]</Hit_def>
  <Hit_accession>YJL165C</Hit_accession>
  <Hit_len>855</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.2098</Hsp_bit-score>
      <Hsp_score>108</Hsp_score>
      <Hsp_evalue>1.43356e-07</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>123</Hsp_query-to>
      <Hsp_hit-from>669</Hsp_hit-from>
      <Hsp_hit-to>708</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>27</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>41</Hsp_align-len>
      <Hsp_qseq>MRAVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFG</Hsp_qseq>
      <Hsp_hseq>MKQLLNGVQYMHDH-GIAHCDLKPENILFQPNGLLKICDFG</Hsp_hseq>
      <Hsp_midline>M+ +L  V Y+HD  G+ H DLKPENIL    G +K+ DFG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.2098</Hsp_bit-score>
      <Hsp_score>108</Hsp_score>
      <Hsp_evalue>1.45241e-07</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>126</Hsp_query-to>
      <Hsp_hit-from>145</Hsp_hit-from>
      <Hsp_hit-to>178</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>22</Hsp_identity>
      <Hsp_positive>26</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>35</Hsp_align-len>
      <Hsp_qseq>VHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGF</Hsp_qseq>
      <Hsp_hseq>VYYAH-SMHCVHRDLKLENILLDKNGNAKLTDFGF</Hsp_hseq>
      <Hsp_midline>V+Y H  +  VHRDLK ENILLD  G+ KL+DFGF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.8246</Hsp_bit-score>
      <Hsp_score>107</Hsp_score>
      <Hsp_evalue>1.73432e-07</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>159</Hsp_hit-from>
      <Hsp_hit-to>199</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>19</Hsp_identity>
      <Hsp_positive>29</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>42</Hsp_align-len>
      <Hsp_qseq>RAVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>QQIISAVEYCHRH-KIVHRDLKPENLLLDEHLNVKIADFGLS</Hsp_hseq>
      <Hsp_midline>+ ++  V Y H    +VHRDLKPEN+LLD   ++K++DFG +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.8246</Hsp_bit-score>
      <Hsp_score>107</Hsp_score>
      <Hsp_evalue>1.85792e-07</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>258</Hsp_hit-from>
      <Hsp_hit-to>299</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>19</Hsp_identity>
      <Hsp_positive>31</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>43</Hsp_align-len>
      <Hsp_qseq>MRAVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>LRGVVLGLEYLHYQ-GIIHRDIKPANLLISGDGTVKISDFGVS</Hsp_hseq>
      <Hsp_midline>+R V+  + YLH + G++HRD+KP N+L+   G +K+SDFG +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YKL198C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:68232:70220:-1 gene:YKL198C transcript:YKL198C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK1 description:Putative serine/threonine protein kinase; regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein; PTK1 has a paralog, PTK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001681]</Hit_def>
  <Hit_accession>YKL198C</Hit_accession>
  <Hit_len>662</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.8246</Hsp_bit-score>
      <Hsp_score>107</Hsp_score>
      <Hsp_evalue>1.93764e-07</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>317</Hsp_hit-from>
      <Hsp_hit-to>351</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>20</Hsp_identity>
      <Hsp_positive>26</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>36</Hsp_align-len>
      <Hsp_qseq>VHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>VKFCHDQ-GIAHRDLKPENVLLSPDGVCKLTDFGIS</Hsp_hseq>
      <Hsp_midline>V + HD+ G+ HRDLKPEN+LL   G  KL+DFG +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.8246</Hsp_bit-score>
      <Hsp_score>107</Hsp_score>
      <Hsp_evalue>2.08847e-07</Hsp_evalue>
      <Hsp_query-from>10</Hsp_query-from>
      <Hsp_query-to>165</Hsp_query-to>
      <Hsp_hit-from>433</Hsp_hit-from>
      <Hsp_hit-to>483</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>32</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>52</Hsp_align-len>
      <Hsp_qseq>VLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFACRLPAPGQPQLR</Hsp_qseq>
      <Hsp_hseq>VVAALEYLH-LLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMK</Hsp_hseq>
      <Hsp_midline>V+  + YLH  +G ++RDLKPENILL   G + LSDF  + +     +P ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YJR059W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:545787:548243:1 gene:YJR059W transcript:YJR059W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK2 description:Serine/threonine protein kinase; involved in regulation of ion transport across plasma membrane; carboxyl terminus is essential for glucose-dependent Pma1p activation via phosphorylation of Pma1p-Ser899; enhances spermine uptake; PTK2 has a paralog, PTK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003820]</Hit_def>
  <Hit_accession>YJR059W</Hit_accession>
  <Hit_len>818</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.4394</Hsp_bit-score>
      <Hsp_score>106</Hsp_score>
      <Hsp_evalue>2.39208e-07</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>370</Hsp_hit-from>
      <Hsp_hit-to>410</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>19</Hsp_identity>
      <Hsp_positive>28</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>42</Hsp_align-len>
      <Hsp_qseq>RAVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>KQVAQGIKFCHDN-GIAHRDLKPENVLISKEGICKLTDFGIS</Hsp_hseq>
      <Hsp_midline>+ V + + + HD  G+ HRDLKPEN+L+   G  KL+DFG +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.4394</Hsp_bit-score>
      <Hsp_score>106</Hsp_score>
      <Hsp_evalue>2.43983e-07</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>138</Hsp_query-to>
      <Hsp_hit-from>294</Hsp_hit-from>
      <Hsp_hit-to>331</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>18</Hsp_identity>
      <Hsp_positive>31</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>39</Hsp_align-len>
      <Hsp_qseq>VHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFACRL</Hsp_qseq>
      <Hsp_hseq>MEYLHDN-KILHRDVKGSNILIDNQGNLKITDFGLARKM</Hsp_hseq>
      <Hsp_midline>+ YLHD   ++HRD+K  NIL+D++G++K++DFG A ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YFL033C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:69115:74427:-1 gene:YFL033C transcript:YFL033C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM15 description:Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase [Source:SGD;Acc:S000001861]</Hit_def>
  <Hit_accession>YFL033C</Hit_accession>
  <Hit_len>1770</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.4394</Hsp_bit-score>
      <Hsp_score>106</Hsp_score>
      <Hsp_evalue>2.5293e-07</Hsp_evalue>
      <Hsp_query-from>46</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>913</Hsp_hit-from>
      <Hsp_hit-to>940</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>16</Hsp_identity>
      <Hsp_positive>24</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>28</Hsp_align-len>
      <Hsp_qseq>GVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>GIIHHDLKPENLLIDNAGHVKLTDFGLS</Hsp_hseq>
      <Hsp_midline>G++H DLKPEN+L+D+ G +KL+DFG +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.4394</Hsp_bit-score>
      <Hsp_score>106</Hsp_score>
      <Hsp_evalue>2.84843e-07</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>265</Hsp_hit-from>
      <Hsp_hit-to>299</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>20</Hsp_identity>
      <Hsp_positive>28</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>36</Hsp_align-len>
      <Hsp_qseq>VHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>LRFLHTK-GVVYRDLKPENCLLNQRGHLVLTDFGLS</Hsp_hseq>
      <Hsp_midline>+ +LH + GVV+RDLKPEN LL+ RG + L+DFG +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.0542</Hsp_bit-score>
      <Hsp_score>105</Hsp_score>
      <Hsp_evalue>3.42721e-07</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>230</Hsp_hit-from>
      <Hsp_hit-to>270</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>20</Hsp_identity>
      <Hsp_positive>28</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>42</Hsp_align-len>
      <Hsp_qseq>RAVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>RGIASALQYLHAN-NIVHRDLKIENIMISSSGEIKIIDFGLS</Hsp_hseq>
      <Hsp_midline>R +   + YLH    +VHRDLK ENI++ S G+IK+ DFG +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.0542</Hsp_bit-score>
      <Hsp_score>105</Hsp_score>
      <Hsp_evalue>3.61687e-07</Hsp_evalue>
      <Hsp_query-from>31</Hsp_query-from>
      <Hsp_query-to>138</Hsp_query-to>
      <Hsp_hit-from>461</Hsp_hit-from>
      <Hsp_hit-to>494</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>28</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>36</Hsp_align-len>
      <Hsp_qseq>LHDEVGVVHRDLKPENILLDSRGDIKLSDFGFACRL</Hsp_qseq>
      <Hsp_hseq>LH-KLDVVYRDLKPENILLDYQGHIALCDFGL-CKL</Hsp_hseq>
      <Hsp_midline>LH ++ VV+RDLKPENILLD +G I L DFG  C+L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.0542</Hsp_bit-score>
      <Hsp_score>105</Hsp_score>
      <Hsp_evalue>3.72523e-07</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>168</Hsp_query-to>
      <Hsp_hit-from>607</Hsp_hit-from>
      <Hsp_hit-to>656</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>31</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>54</Hsp_align-len>
      <Hsp_qseq>AVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFACRLPAPGQPQLRG</Hsp_qseq>
      <Hsp_hseq>AALEYLHLL----GFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKG</Hsp_hseq>
      <Hsp_midline>A LE +H L    G ++RDLKPENILL   G I LSDF  + +      P ++G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>44.669</Hsp_bit-score>
      <Hsp_score>104</Hsp_score>
      <Hsp_evalue>3.92459e-07</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>153</Hsp_query-to>
      <Hsp_hit-from>110</Hsp_hit-from>
      <Hsp_hit-to>159</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>22</Hsp_identity>
      <Hsp_positive>31</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>51</Hsp_align-len>
      <Hsp_qseq>MRAVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFACRLPAPGQ</Hsp_qseq>
      <Hsp_hseq>MLMTLRGVYHCHRNF-ILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHE</Hsp_hseq>
      <Hsp_midline>M   L  V++ H    ++HRDLKP N+L    G IK++DFG A  +PAP +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.0542</Hsp_bit-score>
      <Hsp_score>105</Hsp_score>
      <Hsp_evalue>4.01195e-07</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>138</Hsp_query-to>
      <Hsp_hit-from>495</Hsp_hit-from>
      <Hsp_hit-to>532</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>18</Hsp_identity>
      <Hsp_positive>31</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>39</Hsp_align-len>
      <Hsp_qseq>VHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFACRL</Hsp_qseq>
      <Hsp_hseq>LKFLHNK-KIIHRDIKSDNILLNSQGLVKITDFGFCVEL</Hsp_hseq>
      <Hsp_midline>+ +LH++  ++HRD+K +NILL+S+G +K++DFGF   L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>44.669</Hsp_bit-score>
      <Hsp_score>104</Hsp_score>
      <Hsp_evalue>4.12155e-07</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>180</Hsp_query-to>
      <Hsp_hit-from>561</Hsp_hit-from>
      <Hsp_hit-to>619</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>37</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>60</Hsp_align-len>
      <Hsp_qseq>RAVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFACRL-PAPGQPQLRGELVG</Hsp_qseq>
      <Hsp_hseq>RQILIGVAYLHKK-NIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQG</Hsp_hseq>
      <Hsp_midline>R +L  V YLH +  ++HRD+K  NIL+D +G +K++DFG + +L P   +   R  L G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>44.669</Hsp_bit-score>
      <Hsp_score>104</Hsp_score>
      <Hsp_evalue>5.31155e-07</Hsp_evalue>
      <Hsp_query-from>10</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>1287</Hsp_hit-from>
      <Hsp_hit-to>1325</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>20</Hsp_identity>
      <Hsp_positive>30</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>40</Hsp_align-len>
      <Hsp_qseq>VLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>VLKGLAYLHSK-GILHRDMKADNLLLDQDGICKISDFGIS</Hsp_hseq>
      <Hsp_midline>VL+ + YLH + G++HRD+K +N+LLD  G  K+SDFG +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>44.2838</Hsp_bit-score>
      <Hsp_score>103</Hsp_score>
      <Hsp_evalue>6.1096e-07</Hsp_evalue>
      <Hsp_query-from>31</Hsp_query-from>
      <Hsp_query-to>138</Hsp_query-to>
      <Hsp_hit-from>458</Hsp_hit-from>
      <Hsp_hit-to>491</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>22</Hsp_identity>
      <Hsp_positive>28</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>36</Hsp_align-len>
      <Hsp_qseq>LHDEVGVVHRDLKPENILLDSRGDIKLSDFGFACRL</Hsp_qseq>
      <Hsp_hseq>LH-KLDVIYRDLKPENILLDYQGHIALCDFGL-CKL</Hsp_hseq>
      <Hsp_midline>LH ++ V++RDLKPENILLD +G I L DFG  C+L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>44.2838</Hsp_bit-score>
      <Hsp_score>103</Hsp_score>
      <Hsp_evalue>6.38295e-07</Hsp_evalue>
      <Hsp_query-from>10</Hsp_query-from>
      <Hsp_query-to>126</Hsp_query-to>
      <Hsp_hit-from>933</Hsp_hit-from>
      <Hsp_hit-to>970</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>27</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>39</Hsp_align-len>
      <Hsp_qseq>VLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGF</Hsp_qseq>
      <Hsp_hseq>VLLALKYFHDN-GVIYRDLKLENILLTPEGHIKIADYGL</Hsp_hseq>
      <Hsp_midline>VL  + Y HD  GV++RDLK ENILL   G IK++D+G </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>43.8986</Hsp_bit-score>
      <Hsp_score>102</Hsp_score>
      <Hsp_evalue>8.62766e-07</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>126</Hsp_hit-from>
      <Hsp_hit-to>155</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>17</Hsp_identity>
      <Hsp_positive>24</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>30</Hsp_align-len>
      <Hsp_qseq>EVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>ENKILHRDLKPQNLLINKRGQLKLGDFGLA</Hsp_hseq>
      <Hsp_midline>E  ++HRDLKP+N+L++ RG +KL DFG A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>43.5134</Hsp_bit-score>
      <Hsp_score>101</Hsp_score>
      <Hsp_evalue>1.17906e-06</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>221</Hsp_hit-from>
      <Hsp_hit-to>262</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>29</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>43</Hsp_align-len>
      <Hsp_qseq>RAVLEVVHYLHDEVGVVHRDLKPENILLDSRG-DIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>KQIVEGVSYCH-SFNICHRDLKPENLLLDKKNRRIKIADFGMA</Hsp_hseq>
      <Hsp_midline>+ ++E V Y H    + HRDLKPEN+LLD +   IK++DFG A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>42.743</Hsp_bit-score>
      <Hsp_score>99</Hsp_score>
      <Hsp_evalue>1.95042e-06</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>301</Hsp_hit-from>
      <Hsp_hit-to>343</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>19</Hsp_identity>
      <Hsp_positive>30</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>44</Hsp_align-len>
      <Hsp_qseq>RAVLEVVHYLHDEVGVVHRDLKPENILLDSRGD--IKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>RQILTAIKYIH-SMGISHRDLKPDNILIEQDDPVLVKITDFGLA</Hsp_hseq>
      <Hsp_midline>R +L  + Y+H  +G+ HRDLKP+NIL++      +K++DFG A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YNL183C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:293137:295509:-1 gene:YNL183C transcript:YNL183C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NPR1 description:Protein kinase; stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p; negatively regulates Ldb19p-mediated endocytosis through phosphorylation of Ldb19p, which prevents its association with the plasma membrane; Npr1p activity is negatively regulated via phosphorylation by the TOR complex; NPR1 has a paralog, PRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005127]</Hit_def>
  <Hit_accession>YNL183C</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>42.743</Hsp_bit-score>
      <Hsp_score>99</Hsp_score>
      <Hsp_evalue>1.98337e-06</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>147</Hsp_query-to>
      <Hsp_hit-from>543</Hsp_hit-from>
      <Hsp_hit-to>589</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>20</Hsp_identity>
      <Hsp_positive>30</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>48</Hsp_align-len>
      <Hsp_qseq>RAVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFACRLPAP</Hsp_qseq>
      <Hsp_hseq>KQILTGVQYLH-SIGLAHRDLKLDNCVINEKGIVKLIDFGAAVVFSYP</Hsp_hseq>
      <Hsp_midline>+ +L  V YLH  +G+ HRDLK +N +++ +G +KL DFG A     P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>42.743</Hsp_bit-score>
      <Hsp_score>99</Hsp_score>
      <Hsp_evalue>2.01299e-06</Hsp_evalue>
      <Hsp_query-from>13</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>122</Hsp_hit-from>
      <Hsp_hit-to>159</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>20</Hsp_identity>
      <Hsp_positive>26</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>39</Hsp_align-len>
      <Hsp_qseq>LEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>LRAVKVLHGS-NVIHRDLKPSNLLINSNCDLKVCDFGLA</Hsp_hseq>
      <Hsp_midline>L  V  LH    V+HRDLKP N+L++S  D+K+ DFG A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>42.743</Hsp_bit-score>
      <Hsp_score>99</Hsp_score>
      <Hsp_evalue>2.18758e-06</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>126</Hsp_query-to>
      <Hsp_hit-from>163</Hsp_hit-from>
      <Hsp_hit-to>196</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>19</Hsp_identity>
      <Hsp_positive>28</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>35</Hsp_align-len>
      <Hsp_qseq>VHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGF</Hsp_qseq>
      <Hsp_hseq>VNYMHYK-GLVHRDLKLENLLLDKHENLVITDFGF</Hsp_hseq>
      <Hsp_midline>V+Y+H + G+VHRDLK EN+LLD   ++ ++DFGF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>42.743</Hsp_bit-score>
      <Hsp_score>99</Hsp_score>
      <Hsp_evalue>2.29911e-06</Hsp_evalue>
      <Hsp_query-from>10</Hsp_query-from>
      <Hsp_query-to>144</Hsp_query-to>
      <Hsp_hit-from>145</Hsp_hit-from>
      <Hsp_hit-to>191</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>31</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>48</Hsp_align-len>
      <Hsp_qseq>VLEVVHYLHDEVGVVHRDLKPENILLDSRGD---IKLSDFGFACRLPA</Hsp_qseq>
      <Hsp_hseq>ILSAVKYMHSQ-NIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKS</Hsp_hseq>
      <Hsp_midline>+L  V Y+H +  +VHRDLKPEN+L   + D   + ++DFG A RL +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YKL168C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:131288:133462:-1 gene:YKL168C transcript:YKL168C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KKQ8 description:Putative serine/threonine protein kinase with unknown cellular role; KKQ8 has a paralog, HAL5, that arose from the whole genome duplication [Source:SGD;Acc:S000001651]</Hit_def>
  <Hit_accession>YKL168C</Hit_accession>
  <Hit_len>724</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>42.743</Hsp_bit-score>
      <Hsp_score>99</Hsp_score>
      <Hsp_evalue>2.43991e-06</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>123</Hsp_query-to>
      <Hsp_hit-from>544</Hsp_hit-from>
      <Hsp_hit-to>583</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>20</Hsp_identity>
      <Hsp_positive>27</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>41</Hsp_align-len>
      <Hsp_qseq>MRAVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFG</Hsp_qseq>
      <Hsp_hseq>MKQLLHGVKFMHDH-GIAHCDLKPENILFYPHGLLKICDFG</Hsp_hseq>
      <Hsp_midline>M+ +L  V ++HD  G+ H DLKPENIL    G +K+ DFG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>42.743</Hsp_bit-score>
      <Hsp_score>99</Hsp_score>
      <Hsp_evalue>2.61246e-06</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>134</Hsp_hit-from>
      <Hsp_hit-to>168</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>19</Hsp_identity>
      <Hsp_positive>26</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>36</Hsp_align-len>
      <Hsp_qseq>VHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>LKYLHGE-GVIHRDIKAANILLSADNTVKLADFGVS</Hsp_hseq>
      <Hsp_midline>+ YLH E GV+HRD+K  NILL +   +KL+DFG +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>42.3578</Hsp_bit-score>
      <Hsp_score>98</Hsp_score>
      <Hsp_evalue>2.85105e-06</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>162</Hsp_query-to>
      <Hsp_hit-from>144</Hsp_hit-from>
      <Hsp_hit-to>197</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>22</Hsp_identity>
      <Hsp_positive>34</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>55</Hsp_align-len>
      <Hsp_qseq>MRAVLEVVHYLHDEVGVVHRDLKPENILLDSRG-DIKLSDFGFACRLPAPGQPQL</Hsp_qseq>
      <Hsp_hseq>MFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQL-KPTEPNV</Hsp_hseq>
      <Hsp_midline>M  + + ++YLH    V HRD+KP+N+L+D     +KL DFG A +L  P +P +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YKL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:347214:349136:-1 gene:YKL048C transcript:YKL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ELM1 description:Serine/threonine protein kinase; regulates the orientation checkpoint, the morphogenesis checkpoint and the metabolic switch from fermentative to oxidative metabolism by phosphorylating the activation loop of Kin4p, Hsl1p and Snf4p respectively; cooperates with Hsl7p in recruiting Hsl1p to the septin ring, a prerequisite for subsequent recruitment, phosphorylation, and degradation of Swe1p; forms part of the bud neck ring; regulates cytokinesis [Source:SGD;Acc:S000001531]</Hit_def>
  <Hit_accession>YKL048C</Hit_accession>
  <Hit_len>640</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>42.3578</Hsp_bit-score>
      <Hsp_score>98</Hsp_score>
      <Hsp_evalue>3.13898e-06</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>123</Hsp_query-to>
      <Hsp_hit-from>247</Hsp_hit-from>
      <Hsp_hit-to>280</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>20</Hsp_identity>
      <Hsp_positive>25</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>35</Hsp_align-len>
      <Hsp_qseq>VHYLHDEVGVVHRDLKPENILLDSRGDI-KLSDFG</Hsp_qseq>
      <Hsp_hseq>LEYLHSQ-GCIHRDIKPSNILLDEEEKVAKLSDFG</Hsp_hseq>
      <Hsp_midline>+ YLH + G +HRD+KP NILLD    + KLSDFG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>41.9726</Hsp_bit-score>
      <Hsp_score>97</Hsp_score>
      <Hsp_evalue>3.76254e-06</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>165</Hsp_query-to>
      <Hsp_hit-from>125</Hsp_hit-from>
      <Hsp_hit-to>175</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>34</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>55</Hsp_align-len>
      <Hsp_qseq>MRAVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFACRLPAPGQPQLR</Hsp_qseq>
      <Hsp_hseq>MRELLVALKCIHKD-NVIHRDIKAANVLITNEGNVKLCDFGVAAQV---NQTSLR</Hsp_hseq>
      <Hsp_midline>MR +L  +  +H +  V+HRD+K  N+L+ + G++KL DFG A ++    Q  LR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>41.9726</Hsp_bit-score>
      <Hsp_score>97</Hsp_score>
      <Hsp_evalue>4.16045e-06</Hsp_evalue>
      <Hsp_query-from>10</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>127</Hsp_hit-from>
      <Hsp_hit-to>165</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>18</Hsp_identity>
      <Hsp_positive>27</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>40</Hsp_align-len>
      <Hsp_qseq>VLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>ILRALKSIH-SAQVIHRDIKPSNLLLNSNCDLKVCDFGLA</Hsp_hseq>
      <Hsp_midline>+L  +  +H    V+HRD+KP N+LL+S  D+K+ DFG A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>41.9726</Hsp_bit-score>
      <Hsp_score>97</Hsp_score>
      <Hsp_evalue>4.37692e-06</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>165</Hsp_query-to>
      <Hsp_hit-from>176</Hsp_hit-from>
      <Hsp_hit-to>228</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>34</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>55</Hsp_align-len>
      <Hsp_qseq>MRAVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFACRLPAPGQPQLR</Hsp_qseq>
      <Hsp_hseq>MLQILEGLNYIHC-AKFMHRDIKTANILIDHNGVLKLADFGLA-RLYYGCPPNLK</Hsp_hseq>
      <Hsp_midline>M  +LE ++Y+H     +HRD+K  NIL+D  G +KL+DFG A RL     P L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YBR059C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:356861:360187:-1 gene:YBR059C transcript:YBR059C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AKL1 description:Ser-Thr protein kinase; member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization [Source:SGD;Acc:S000000263]</Hit_def>
  <Hit_accession>YBR059C</Hit_accession>
  <Hit_len>1108</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>41.9726</Hsp_bit-score>
      <Hsp_score>97</Hsp_score>
      <Hsp_evalue>4.57474e-06</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>123</Hsp_query-to>
      <Hsp_hit-from>170</Hsp_hit-from>
      <Hsp_hit-to>201</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>17</Hsp_identity>
      <Hsp_positive>27</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>34</Hsp_align-len>
      <Hsp_qseq>VHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFG</Hsp_qseq>
      <Hsp_hseq>MHYL--PVSLIHRDIKIENVLVDAKNNFKLADFG</Hsp_hseq>
      <Hsp_midline>+HYL   V ++HRD+K EN+L+D++ + KL+DFG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YDL214C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:74446:76545:-1 gene:YDL214C transcript:YDL214C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR2 description:Serine/threonine protein kinase; inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance; PRR2 has a paralog, NPR1, that arose from the whole genome duplication [Source:SGD;Acc:S000002373]</Hit_def>
  <Hit_accession>YDL214C</Hit_accession>
  <Hit_len>699</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>41.5874</Hsp_bit-score>
      <Hsp_score>96</Hsp_score>
      <Hsp_evalue>5.39465e-06</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>162</Hsp_query-to>
      <Hsp_hit-from>466</Hsp_hit-from>
      <Hsp_hit-to>517</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>32</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>53</Hsp_align-len>
      <Hsp_qseq>RAVLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFACRLPAPGQPQL</Hsp_qseq>
      <Hsp_hseq>KQLINGVKYLHD-IGLSHRDLKLDNCVVTRRGILKLIDFGASSVFHYPLSSQM</Hsp_hseq>
      <Hsp_midline>+ ++  V YLHD +G+ HRDLK +N ++  RG +KL DFG +     P   Q+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>41.5874</Hsp_bit-score>
      <Hsp_score>96</Hsp_score>
      <Hsp_evalue>5.95684e-06</Hsp_evalue>
      <Hsp_query-from>10</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>211</Hsp_hit-from>
      <Hsp_hit-to>249</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>17</Hsp_identity>
      <Hsp_positive>28</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>40</Hsp_align-len>
      <Hsp_qseq>VLEVVHYLHDEVGVVHRDLKPENILLDSRGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>IANALDYMHKK-NIIHRDIKPENILIGFNNVIKLTDFGWS</Hsp_hseq>
      <Hsp_midline>+   + Y+H +  ++HRD+KPENIL+     IKL+DFG++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>41.2022</Hsp_bit-score>
      <Hsp_score>95</Hsp_score>
      <Hsp_evalue>8.73332e-06</Hsp_evalue>
      <Hsp_query-from>10</Hsp_query-from>
      <Hsp_query-to>129</Hsp_query-to>
      <Hsp_hit-from>191</Hsp_hit-from>
      <Hsp_hit-to>230</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>18</Hsp_identity>
      <Hsp_positive>30</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>41</Hsp_align-len>
      <Hsp_qseq>VLEVVHYLHDEVGVVHRDLKPENILLDS-RGDIKLSDFGFA</Hsp_qseq>
      <Hsp_hseq>IMDAIEYVHNK-GIYHRDIKPENILISGIDWTIKLTDWGLA</Hsp_hseq>
      <Hsp_midline>+++ + Y+H++ G+ HRD+KPENIL+      IKL+D+G A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>76</Statistics_hsp-len>
      <Statistics_eff-space>77198944</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056511-RA transcript Note:&quot;Similar to CSMD1 CUB and sushi domain-containing protein 1 (Homo sapiens)&quot; offset:0 AED:0.25 eAED:0.25 QI:0|0.66|0.84|0.92|0.41|0.38|13|513|442</Iteration_query-def>
  <Iteration_query-len>1842</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1186987773</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056512-RA transcript Note:&quot;Similar to CSMD3 CUB and sushi domain-containing protein 3 (Homo sapiens)&quot; offset:0 AED:0.17 eAED:0.18 QI:0|0.60|0.58|0.95|0.43|0.5|24|0|566</Iteration_query-def>
  <Iteration_query-len>1701</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1079495624</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056513-RA transcript Note:&quot;Similar to CSMD3 CUB and sushi domain-containing protein 3 (Homo sapiens)&quot; offset:2 AED:0.29 eAED:0.29 QI:2|0|0|0.83|0.82|0.88|18|0|918</Iteration_query-def>
  <Iteration_query-len>2759</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>1853746940</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056514-RA transcript Note:&quot;Similar to Csmd1 CUB and sushi domain-containing protein 1 (Mus musculus)&quot; offset:562 AED:0.23 eAED:0.23 QI:562|0.57|0.87|1|0.42|0.37|8|854|198</Iteration_query-def>
  <Iteration_query-len>2013</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1311268525</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056515-RA transcript Note:&quot;Similar to CSMD3 CUB and sushi domain-containing protein 3 (Homo sapiens)&quot; offset:0 AED:0.44 eAED:0.44 QI:0|0|0|0.5|1|1|2|0|68</Iteration_query-def>
  <Iteration_query-len>207</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>42</Statistics_hsp-len>
      <Statistics_eff-space>71195409</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056516-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.46 eAED:1.00 QI:0|0|0|0.33|1|1|6|0|666</Iteration_query-def>
  <Iteration_query-len>2001</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1302146657</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056517-RA transcript Note:&quot;Similar to Csmd3 CUB and sushi domain-containing protein 3 (Mus musculus)&quot; offset:0 AED:0.13 eAED:0.13 QI:0|0|0|1|1|1|2|0|164</Iteration_query-def>
  <Iteration_query-len>495</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>83</Statistics_hsp-len>
      <Statistics_eff-space>194033894</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056518-RA transcript Note:&quot;Similar to CSMD1 CUB and sushi domain-containing protein 1 (Homo sapiens)&quot; offset:0 AED:0.11 eAED:0.11 QI:0|0|0|0.5|1|1|2|0|85</Iteration_query-def>
  <Iteration_query-len>258</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>57</Statistics_hsp-len>
      <Statistics_eff-space>73598143</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

