<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0041398-RA transcript Note:&quot;Similar to asic1a Acid-sensing ion channel 1A (Danio rerio)&quot; offset:0 AED:0.36 eAED:0.36 QI:0|0|0|0.5|0|0|4|0|382</BlastOutput_query-def>
  <BlastOutput_query-len>1149</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0041398-RA transcript Note:&quot;Similar to asic1a Acid-sensing ion channel 1A (Danio rerio)&quot; offset:0 AED:0.36 eAED:0.36 QI:0|0|0|0.5|0|0|4|0|382</Iteration_query-def>
  <Iteration_query-len>1149</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>675532364</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0041399-RA transcript Note:&quot;Similar to ASIC1 Acid-sensing ion channel 1 (Gallus gallus)&quot; offset:0 AED:0.35 eAED:0.38 QI:0|-1|0|1|-1|1|1|0|207</Iteration_query-def>
  <Iteration_query-len>624</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>85</Statistics_hsp-len>
      <Statistics_eff-space>289427241</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0028656-RA transcript Note:&quot;Similar to Abi1 Abl interactor 1 (Rattus norvegicus)&quot; offset:307 AED:0.20 eAED:0.20 QI:307|0.5|0.45|0.90|0|0.09|11|1671|334</Iteration_query-def>
  <Iteration_query-len>2983</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YFR024C-A</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:201960:203433:-1 gene:YFR024C-A transcript:YFR024C-A_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:LSB3 description:Protein containing a C-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization; protein abundance increases in response to DNA replication stress; LSB3 has a paralog, YSC84, that arose from the whole genome duplication [Source:SGD;Acc:S000002968]</Hit_def>
  <Hit_accession>YFR024C-A</Hit_accession>
  <Hit_len>459</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>6.24027e-09</Hsp_evalue>
      <Hsp_query-from>1106</Hsp_query-from>
      <Hsp_query-to>1294</Hsp_query-to>
      <Hsp_hit-from>395</Hsp_hit-from>
      <Hsp_hit-to>459</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>43</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>65</Hsp_align-len>
      <Hsp_qseq>PWAPKSYLEKVVAVYDYNKDKEDELSFQEGSIIYVIKKND--DGWYEGTMNGQTGLFPGNYVEPI</Hsp_qseq>
      <Hsp_hseq>PTSPSTSSPKAVALYSFAGEESGDLPFRKGDVITILKKSDSQNDWWTGRVNGREGIFPANYVELV</Hsp_hseq>
      <Hsp_midline>P +P +   K VA+Y +  ++  +L F++G +I ++KK+D  + W+ G +NG+ G+FP NYVE +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YHL002W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:102612:103970:1 gene:YHL002W transcript:YHL002W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSE1 description:Subunit of the endosomal Vps27p-Hse1p complex; complex is required for sorting of ubiquitinated membrane proteins into intralumenal vesicles prior to vacuolar degradation, as well as for recycling of Golgi proteins and formation of lumenal membranes [Source:SGD;Acc:S000000994]</Hit_def>
  <Hit_accession>YHL002W</Hit_accession>
  <Hit_len>452</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>6.99951e-09</Hsp_evalue>
      <Hsp_query-from>1118</Hsp_query-from>
      <Hsp_query-to>1297</Hsp_query-to>
      <Hsp_hit-from>216</Hsp_hit-from>
      <Hsp_hit-to>275</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>41</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>60</Hsp_align-len>
      <Hsp_qseq>KSYLEKVVAVYDYNKDKEDELSFQEGSIIYVIKKNDDGWYEGTMNGQTGLFPGNYVEPIL</Hsp_qseq>
      <Hsp_hseq>QTVVRRVRALYDLTTNEPDELSFRKGDVITVLEQVYRDWWKGALRGNMGIFPLNYVTPIV</Hsp_hseq>
      <Hsp_midline>++ + +V A+YD   ++ DELSF++G +I V+++    W++G + G  G+FP NYV PI+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YPR154W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:834565:835212:1 gene:YPR154W transcript:YPR154W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PIN3 description:Negative regulator of actin nucleation-promoting factor activity; interacts with Las17p, a homolog of human Wiskott-Aldrich Syndrome protein (WASP), via an N-terminal SH3 domain, and along with LSB1 cooperatively inhibits the nucleation of actin filaments; short-lived protein whose levels increase in response to thermal stress; induces the formation of the [PIN+] and [RNQ+] prions when overproduced; PIN3 has a paralog, LSB1, that arose from the whole genome duplication [Source:SGD;Acc:S000006358]</Hit_def>
  <Hit_accession>YPR154W</Hit_accession>
  <Hit_len>215</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>1.40657e-08</Hsp_evalue>
      <Hsp_query-from>1091</Hsp_query-from>
      <Hsp_query-to>1297</Hsp_query-to>
      <Hsp_hit-from>40</Hsp_hit-from>
      <Hsp_hit-to>112</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>26</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>73</Hsp_align-len>
      <Hsp_qseq>AEADPPWAPK----SYLEKVVAVYDYNKDKEDELSFQEGSIIYVIKKNDDGWYEGTMNGQTGLFPGNYVEPIL</Hsp_qseq>
      <Hsp_hseq>AKWDPANAPRNASPASLEYVEALYQFDPQQDGDLGLKPGDKVQLLEKLSPEWYKGSCNGRTGIFPANYVKPAF</Hsp_hseq>
      <Hsp_midline>A+ DP  AP+    + LE V A+Y ++  ++ +L  + G  + +++K    WY+G+ NG+TG+FP NYV+P  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YGR136W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:762428:763153:1 gene:YGR136W transcript:YGR136W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:LSB1 description:Negative regulator of actin nucleation-promoting factor activity; interacts with Las17p, a homolog of human Wiskott-Aldrich Syndrome protein (WASP), via an N-terminal SH3 domain, and along with PIN3 cooperatively inhibits the nucleation of actin filaments; overexpression blocks receptor-mediated endocytosis; protein increases in abundance and forms nuclear foci in response to DNA replication stress; LSB1 has a paralog, PIN3, that arose from the whole genome duplication [Source:SGD;Acc:S000003368]</Hit_def>
  <Hit_accession>YGR136W</Hit_accession>
  <Hit_len>241</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>1.27636e-07</Hsp_evalue>
      <Hsp_query-from>1130</Hsp_query-from>
      <Hsp_query-to>1297</Hsp_query-to>
      <Hsp_hit-from>56</Hsp_hit-from>
      <Hsp_hit-to>111</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>22</Hsp_identity>
      <Hsp_positive>33</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>56</Hsp_align-len>
      <Hsp_qseq>EKVVAVYDYNKDKEDELSFQEGSIIYVIKKNDDGWYEGTMNGQTGLFPGNYVEPIL</Hsp_qseq>
      <Hsp_hseq>EYVEALYDFEAQQDGDLSLKTGDKIQVLEKISPDWYRGKSNNKIGIFPANYVKPAF</Hsp_hseq>
      <Hsp_midline>E V A+YD+   ++ +LS + G  I V++K    WY G  N + G+FP NYV+P  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YDR388W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1250186:1251634:1 gene:YDR388W transcript:YDR388W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RVS167 description:Calmodulin-binding actin-associated protein; roles in endocytic membrane tabulation and constriction, and exocytosis; N-BAR domain protein that interacts with Rvs161p to regulate actin cytoskeleton, endocytosis, and viability following starvation or osmotic stress; recruited to bud tips by Gyl1p and Gyp5p during polarized growth; homolog of mammalian amphiphysin [Source:SGD;Acc:S000002796]</Hit_def>
  <Hit_accession>YDR388W</Hit_accession>
  <Hit_len>482</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>1.4509e-07</Hsp_evalue>
      <Hsp_query-from>1130</Hsp_query-from>
      <Hsp_query-to>1288</Hsp_query-to>
      <Hsp_hit-from>424</Hsp_hit-from>
      <Hsp_hit-to>478</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>35</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>55</Hsp_align-len>
      <Hsp_qseq>EKVVAVYDYNKDKEDELSFQEGSIIYVIKKNDD--GWYEGTMNGQTGLFPGNYVE</Hsp_qseq>
      <Hsp_hseq>ETVTALYDYQAQAAGDLSFPAGAVIEIVQRTPDVNEWWTGRYNGQQGVFPGNYVQ</Hsp_hseq>
      <Hsp_midline>E V A+YDY      +LSF  G++I ++++  D   W+ G  NGQ G+FPGNYV+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YHR016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:136881:138455:-1 gene:YHR016C transcript:YHR016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YSC84 description:Actin-binding protein; involved in bundling of actin filaments and endocytosis of actin cortical patches; activity stimulated by Las17p; contains SH3 domain similar to Rvs167p; YSC84 has a paralog, LSB3, that arose from the whole genome duplication [Source:SGD;Acc:S000001058]</Hit_def>
  <Hit_accession>YHR016C</Hit_accession>
  <Hit_len>468</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>9.89331e-07</Hsp_evalue>
      <Hsp_query-from>1136</Hsp_query-from>
      <Hsp_query-to>1285</Hsp_query-to>
      <Hsp_hit-from>414</Hsp_hit-from>
      <Hsp_hit-to>465</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>20</Hsp_identity>
      <Hsp_positive>37</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>52</Hsp_align-len>
      <Hsp_qseq>VVAVYDYNKDKEDELSFQEGSIIYVIKKND--DGWYEGTMNGQTGLFPGNYV</Hsp_qseq>
      <Hsp_hseq>AVALYNFAGEQPGDLAFKKGDVITILKKSDSQNDWWTGRTNGKEGIFPANYV</Hsp_hseq>
      <Hsp_midline> VA+Y++  ++  +L+F++G +I ++KK+D  + W+ G  NG+ G+FP NYV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>2023296965</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052090-RA transcript Note:&quot;Similar to TANC2 Protein TANC2 (Homo sapiens)&quot; offset:717 AED:0.09 eAED:0.09 QI:717|0.77|0.9|1|0.55|0.5|10|648|662</Iteration_query-def>
  <Iteration_query-len>3354</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2294640206</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052091-RA transcript Note:&quot;Similar to TANC2 Protein TANC2 (Homo sapiens)&quot; offset:1 AED:0.11 eAED:0.72 QI:1|0.71|0.62|0.87|1|1|8|0|831</Iteration_query-def>
  <Iteration_query-len>2497</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YOR034C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:394837:397086:-1 gene:YOR034C transcript:YOR034C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AKR2 description:Ankyrin repeat-containing protein; member of a family of putative palmitoyltransferases containing an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; possibly involved in constitutive endocytosis of Ste3p; AKR2 has a paralog, AKR1, that arose from the whole genome duplication [Source:SGD;Acc:S000005560]</Hit_def>
  <Hit_accession>YOR034C</Hit_accession>
  <Hit_len>749</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>1.50937e-11</Hsp_evalue>
      <Hsp_query-from>41</Hsp_query-from>
      <Hsp_query-to>463</Hsp_query-to>
      <Hsp_hit-from>102</Hsp_hit-from>
      <Hsp_hit-to>249</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>148</Hsp_align-len>
      <Hsp_qseq>LLLRRGAEPD-APERRGRTALMAAACEGHTNTVDVLLSRGANVSVADHEGLSALSWACLKGRLAVVQTLLA------HGAPVNHADRSGRTPLGLAAFHGDAEVVQFLLEHGANMEHVDESGMRPLDRAIGCRNTAVVLALLKKGANL</Hsp_qseq>
      <Hsp_hseq>FLLLRGANPNQAAGPGGATALHWAARYGNIYIVDLLLKHGADPTLKDEQGLNIMHFSVYSSNILLVVYVLYFVVNNNDNVDIDSKDNNNRTPLLWAAYQGDFLTVELLLKFGSTVAWTDNRGFNALHCALVGGDQRVICDLILSGANF</Hsp_hseq>
      <Hsp_midline> LL RGA P+ A    G TAL  AA  G+   VD+LL  GA+ ++ D +GL+ + ++     + +V  +L           ++  D + RTPL  AA+ GD   V+ LL+ G+ +   D  G   L  A+   +  V+  L+  GAN </Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>3.69521e-08</Hsp_evalue>
      <Hsp_query-from>98</Hsp_query-from>
      <Hsp_query-to>421</Hsp_query-to>
      <Hsp_hit-from>54</Hsp_hit-from>
      <Hsp_hit-to>163</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>110</Hsp_align-len>
      <Hsp_qseq>LMAAACEGHTNTV-DVLLSRGANVSVADHEGLSALSWACLKGRLAVVQTLLAHGA-PVNHADRSGRTPLGLAAFHGDAEVVQFLLEHGANMEHVDESGMRPLDRAIGCRN</Hsp_qseq>
      <Hsp_hseq>FIEAAKDGDLKVVKDVVESGAVDINNDRIDELSGLHWACINNRFSVAKFLLLRGANPNQAAGPGGATALHWAARYGNIYIVDLLLKHGADPTLKDEQGLNIMHFSVYSSN</Hsp_hseq>
      <Hsp_midline> + AA +G    V DV+ S   +++    + LS L WAC+  R +V + LL  GA P   A   G T L  AA +G+  +V  LL+HGA+    DE G+  +  ++   N</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YDR264C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:996029:998323:-1 gene:YDR264C transcript:YDR264C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AKR1 description:Palmitoyl transferase involved in protein palmitoylation; acts as a negative regulator of pheromone response pathway; required for endocytosis of pheromone receptors; involved in cell shape control; contains ankyrin repeats; AKR1 has a paralog, AKR2, that arose from the whole genome duplication; any of several human homologs encoding DHHC-type zinc fingers (ZDHHC) can complement temperature sensitivity of yeast akr1 null mutant [Source:SGD;Acc:S000002672]</Hit_def>
  <Hit_accession>YDR264C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>2.01967e-09</Hsp_evalue>
      <Hsp_query-from>182</Hsp_query-from>
      <Hsp_query-to>445</Hsp_query-to>
      <Hsp_hit-from>108</Hsp_hit-from>
      <Hsp_hit-to>196</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>91</Hsp_align-len>
      <Hsp_qseq>EGLSALSWACLKGRLAVVQTLLAHGAPVNHADRSGR---TPLGLAAFHGDAEVVQFLLEHGANMEHVDESGMRPLDRAIGCRNTAVVLALL</Hsp_qseq>
      <Hsp_hseq>EHITGLHWASINNRLSVVDFLVSQGADVNA--RAGALHATPLHWAARYGYVYIVDFLLKHGADPTMTDDQGFNLLHLSVNSSNIMLVLYVL</Hsp_hseq>
      <Hsp_midline>E ++ L WA +  RL+VV  L++ GA VN   R+G    TPL  AA +G   +V FLL+HGA+    D+ G   L  ++   N  +VL +L</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>1.43028e-08</Hsp_evalue>
      <Hsp_query-from>62</Hsp_query-from>
      <Hsp_query-to>307</Hsp_query-to>
      <Hsp_hit-from>206</Hsp_hit-from>
      <Hsp_hit-to>287</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>82</Hsp_align-len>
      <Hsp_qseq>EPDAPERRGRTALMAAACEGHTNTVDVLLSRGANVSVADHEGLSALSWACLKGRLAVVQTLLAHGAPVNHADRSGRTPLGLA</Hsp_qseq>
      <Hsp_hseq>DIDCRDPKGRTSLLWAAYQGDSLTVAELLKFGASIKIADTEGFTPLHWGTVKGQPHVLKYLIQDGADFFQKTDTGKDCFAIA</Hsp_hseq>
      <Hsp_midline>+ D  + +GRT+L+ AA +G + TV  LL  GA++ +AD EG + L W  +KG+  V++ L+  GA       +G+    +A</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>2.47135e-08</Hsp_evalue>
      <Hsp_query-from>29</Hsp_query-from>
      <Hsp_query-to>463</Hsp_query-to>
      <Hsp_hit-from>123</Hsp_hit-from>
      <Hsp_hit-to>273</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>153</Hsp_align-len>
      <Hsp_qseq>QVVLLLLRRGAEPDAPERRGR---TALMAAACEGHTNTVDVLLSRGANVSVADHEGLSALSWACLKGRLAVVQTLLAHGAP-----VNHADRSGRTPLGLAAFHGDAEVVQFLLEHGANMEHVDESGMRPLDRAIGCRNTAVVLALLKKGANL</Hsp_qseq>
      <Hsp_hseq>SVVDFLVSQGADVNA--RAGALHATPLHWAARYGYVYIVDFLLKHGADPTMTDDQGFNLLHLSVNSSNIMLVLYVLFNVVSKGLLDIDCRDPKGRTSLLWAAYQGDSLTVAELLKFGASIKIADTEGFTPLHWGTVKGQPHVLKYLIQDGADF</Hsp_hseq>
      <Hsp_midline> VV  L+ +GA+ +A  R G    T L  AA  G+   VD LL  GA+ ++ D +G + L  +     + +V  +L +        ++  D  GRT L  AA+ GD+  V  LL+ GA+++  D  G  PL          V+  L++ GA+ </Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>4</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>2.73819e-08</Hsp_evalue>
      <Hsp_query-from>23</Hsp_query-from>
      <Hsp_query-to>385</Hsp_query-to>
      <Hsp_hit-from>155</Hsp_hit-from>
      <Hsp_hit-to>280</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>126</Hsp_align-len>
      <Hsp_qseq>HTQVVLLLLRRGAEPDAPERRGRTALMAAACEGHTNTVDVLL----SRGA-NVSVADHEGLSALSWACLKGRLAVVQTLLAHGAPVNHADRSGRTPLGLAAFHGDAEVVQFLLEHGANMEHVDESG</Hsp_qseq>
      <Hsp_hseq>YVYIVDFLLKHGADPTMTDDQGFNLLHLSVNSSNIMLVLYVLFNVVSKGLLDIDCRDPKGRTSLLWAAYQGDSLTVAELLKFGASIKIADTEGFTPLHWGTVKGQPHVLKYLIQDGADFFQKTDTG</Hsp_hseq>
      <Hsp_midline>+  +V  LL+ GA+P   + +G   L  +    +   V  +L    S+G  ++   D +G ++L WA  +G    V  LL  GA +  AD  G TPL      G   V+++L++ GA+     ++G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YIR033W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:416124:419465:1 gene:YIR033W transcript:YIR033W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MGA2 description:ER membrane protein involved in regulation of OLE1 transcription; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting; MGA2 has a paralog, SPT23, that arose from the whole genome duplication [Source:SGD;Acc:S000001472]</Hit_def>
  <Hit_accession>YIR033W</Hit_accession>
  <Hit_len>1113</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>1.22038e-07</Hsp_evalue>
      <Hsp_query-from>146</Hsp_query-from>
      <Hsp_query-to>388</Hsp_query-to>
      <Hsp_hit-from>707</Hsp_hit-from>
      <Hsp_hit-to>787</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>43</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>81</Hsp_align-len>
      <Hsp_qseq>LSRGANVSVADHEGLSALSWACLKGRLAVVQTLLAHGAPVNHADRSGRTPLGLAAFHGDAEVVQFLLEHGANMEHVDESGM</Hsp_qseq>
      <Hsp_hseq>LNINSNISICDSLGRTLLHLACLKNYSSLVYTLIKKGARVNDIDSFGLTPLHFACISGDPKIIKMLLNCKVNYSLRSHNGL</Hsp_hseq>
      <Hsp_midline>L+  +N+S+ D  G + L  ACLK   ++V TL+  GA VN  D  G TPL  A   GD ++++ LL    N      +G+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YIL112W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:151595:154846:1 gene:YIL112W transcript:YIL112W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOS4 description:Subunit of the Set3 complex; complex is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; potential Cdc28p substrate [Source:SGD;Acc:S000001374]</Hit_def>
  <Hit_accession>YIL112W</Hit_accession>
  <Hit_len>1083</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>1.70398e-07</Hsp_evalue>
      <Hsp_query-from>176</Hsp_query-from>
      <Hsp_query-to>460</Hsp_query-to>
      <Hsp_hit-from>327</Hsp_hit-from>
      <Hsp_hit-to>424</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>53</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>98</Hsp_align-len>
      <Hsp_qseq>DHEGLSALSWACLKGRLAVVQTLLAHGA-PVNHADRSGRTPLGLAAFHGDAEVVQFLLEHGA--NMEHVDESGMRPLDRAIGCRNTAVVLALLKKGAN</Hsp_qseq>
      <Hsp_hseq>DSGGRTRLQIACDKGKYDVVKKMIEEGGYDINDQDNAGNTALHEAALQGHIEIVELLIENGADVNIKSIEMFGDTPLIDASANGHLDVVKYLLKNGAD</Hsp_hseq>
      <Hsp_midline>D  G + L  AC KG+  VV+ ++  G   +N  D +G T L  AA  G  E+V+ L+E+GA  N++ ++  G  PL  A    +  VV  LLK GA+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1664173978</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052092-RA transcript Note:&quot;Similar to Adcy1 Adenylate cyclase type 1 (Mus musculus)&quot; offset:0 AED:0.12 eAED:0.13 QI:0|0|0|0.9|0.77|0.8|10|0|618</Iteration_query-def>
  <Iteration_query-len>1857</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1198423108</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052093-RA transcript Note:&quot;Similar to PKD1L1 Polycystic kidney disease protein 1-like 1 (Homo sapiens)&quot; offset:0 AED:0.49 eAED:0.50 QI:0|0|0|0.05|0.90|0.96|54|0|3440</Iteration_query-def>
  <Iteration_query-len>10323</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>108</Statistics_hsp-len>
      <Statistics_eff-space>7336822911</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0026332-RA transcript Note:&quot;Similar to TNS1 Tensin-1 (Homo sapiens)&quot; offset:0 AED:0.95 eAED:1.00 QI:0|0|0|0.03|0.29|0.28|28|1494|1052</Iteration_query-def>
  <Iteration_query-len>4653</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3235218616</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0029791-RA transcript Note:&quot;Similar to gjc1 Gap junction gamma-1 protein (Xenopus tropicalis)&quot; offset:0 AED:0.46 eAED:0.65 QI:0|0|0.25|0.75|0|0|4|0|208</Iteration_query-def>
  <Iteration_query-len>627</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>85</Statistics_hsp-len>
      <Statistics_eff-space>291780308</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0027844-RA transcript Note:&quot;Similar to OBSCN Obscurin (Homo sapiens)&quot; offset:1286 AED:1.00 eAED:1.00 QI:1286|0|0|0|0.52|0.35|20|0|1020</Iteration_query-def>
  <Iteration_query-len>4349</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>102</Statistics_hsp-len>
      <Statistics_eff-space>3018447849</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0029792-RA transcript Note:&quot;Similar to OBSCN Obscurin (Homo sapiens)&quot; offset:650 AED:1.00 eAED:1.00 QI:650|0|0|0|0.16|0.38|13|436|444</Iteration_query-def>
  <Iteration_query-len>2421</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1607492303</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0034170-RA transcript Note:&quot;Similar to Obscn Obscurin (Mus musculus)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.33|0.25|4|0|201</Iteration_query-def>
  <Iteration_query-len>606</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>85</Statistics_hsp-len>
      <Statistics_eff-space>275308839</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0010352-RA transcript Note:&quot;Similar to OBSCN Obscurin (Homo sapiens)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.63|0.58|12|2|902</Iteration_query-def>
  <Iteration_query-len>2708</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1822882668</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0041430-RA transcript Note:&quot;Similar to Obscn Obscurin (Mus musculus)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.8|0.87|16|0|883</Iteration_query-def>
  <Iteration_query-len>2652</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1782071862</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0003832-RA transcript Note:&quot;Similar to speg Striated muscle preferentially expressed protein kinase (Danio rerio)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|-1|0|0|-1|1|1|1|155</Iteration_query-def>
  <Iteration_query-len>466</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>82</Statistics_hsp-len>
      <Statistics_eff-space>173219291</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052094-RA transcript Note:&quot;Similar to SPEG Striated muscle preferentially expressed protein kinase (Homo sapiens)&quot; offset:0 AED:0.83 eAED:0.88 QI:0|0.06|0.03|0.13|1|1|30|0|2178</Iteration_query-def>
  <Iteration_query-len>6537</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>103.605</Hsp_bit-score>
      <Hsp_score>257</Hsp_score>
      <Hsp_evalue>3.30049e-23</Hsp_evalue>
      <Hsp_query-from>1672</Hsp_query-from>
      <Hsp_query-to>2307</Hsp_query-to>
      <Hsp_hit-from>53</Hsp_hit-from>
      <Hsp_hit-to>294</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>242</Hsp_align-len>
      <Hsp_qseq>IGRGTFSVVRRAVHRTTGLEVAAKFVSRAGGRRSEAQ-----RELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK-------------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQ---------PVSTATDICLSGTSPFLGENDRGTLMRVREGRFSLER---CFSALSAEAGSFIARLLAVDP</Hsp_qseq>
      <Hsp_hseq>LGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSPFIAESVEGFMEECTASRYPVTFHMPYWDNISIDVKRFILKALRLNP</Hsp_hseq>
      <Hsp_midline>+G G+F VVR+A   +T  +VA K + +   + +  Q      EL IL ++SHP +   +D F+++ +  I+T+L +G EL DR++ +   +E+     I QIL  V Y+H   V+H D+K              + + D G A++L       Y A G+  +VAPE++ Q           +   T   L G SPF+ E+  G +      R+ +      +  +S +   FI + L ++P</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>90.5077</Hsp_bit-score>
      <Hsp_score>223</Hsp_score>
      <Hsp_evalue>5.61531e-19</Hsp_evalue>
      <Hsp_query-from>5731</Hsp_query-from>
      <Hsp_query-to>6333</Hsp_query-to>
      <Hsp_hit-from>58</Hsp_hit-from>
      <Hsp_hit-to>261</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>209</Hsp_align-len>
      <Hsp_qseq>FGVIRECKENATGRVFTAKIV---PLEAASRALAL--HEYEVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRK---LKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPFLGANDEETEKNIRQC</Hsp_qseq>
      <Hsp_hseq>FGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQL--KGEEDLIYKAAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSPFIA---ESVEGFMEEC</Hsp_hseq>
      <Hsp_midline>FGV+R+ ++ +T      KI+    L+  +  L +   E  +L+ L   +I+   + + +     ++ +   G ELF ++L   ++TE D V  + Q+L A+ Y+H +++VH D+K +N++  D  +   L + DFG A+     G    I    G+L + APE++  D  G P D+W + V+T+ LL G SPF+    E  E  + +C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>103.219</Hsp_bit-score>
      <Hsp_score>256</Hsp_score>
      <Hsp_evalue>3.98575e-23</Hsp_evalue>
      <Hsp_query-from>1672</Hsp_query-from>
      <Hsp_query-to>2307</Hsp_query-to>
      <Hsp_hit-from>43</Hsp_hit-from>
      <Hsp_hit-to>284</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>242</Hsp_align-len>
      <Hsp_qseq>IGRGTFSVVRRAVHRTTGLEVAAKFVSRAGGRRSEAQ-----RELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIKEVKL-------------CDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQ---------PVSTATDICLSGTSPFLGENDRGTLMRVREGRFSLER---CFSALSAEAGSFIARLLAVDP</Hsp_qseq>
      <Hsp_hseq>LGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNKAKQFILKALNLDP</Hsp_hseq>
      <Hsp_midline>+G GTF VVR+A +  TG +VA K + +   + ++ Q      EL IL R+ HP +   +D F+++ +  I+T+L  G EL DR++KK   +E      + +IL  V Y+H   ++H D+K   L              D G A+ L    +  Y   G+  +VAPE++ Q           +   T   L G S F  E  +  L     G + ++     + ++S +A  FI + L +DP</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>91.6633</Hsp_bit-score>
      <Hsp_score>226</Hsp_score>
      <Hsp_evalue>2.44547e-19</Hsp_evalue>
      <Hsp_query-from>5731</Hsp_query-from>
      <Hsp_query-to>6288</Hsp_query-to>
      <Hsp_hit-from>48</Hsp_hit-from>
      <Hsp_hit-to>239</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>194</Hsp_align-len>
      <Hsp_qseq>FGVIRECKENATGRVFTAKIVPLEAAS----RALALH-EYEVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIV---SDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPF</Hsp_qseq>
      <Hsp_hseq>FGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSD--EELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAF</Hsp_hseq>
      <Hsp_midline>FGV+R+ K   TG     KI+  +A      +  AL+ E ++L+ L   +I+   + + +     +I +   G ELF ++L+  ++TE+D V  L ++L A+ Y+H ++IVH D+K +NL+    SD   L + DFG A+          +    G+L + APE++  D  G P D+W + V+T+ LL G S F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>96.2857</Hsp_bit-score>
      <Hsp_score>238</Hsp_score>
      <Hsp_evalue>2.54684e-20</Hsp_evalue>
      <Hsp_query-from>1648</Hsp_query-from>
      <Hsp_query-to>2307</Hsp_query-to>
      <Hsp_hit-from>196</Hsp_hit-from>
      <Hsp_hit-to>451</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>258</Hsp_align-len>
      <Hsp_qseq>DYYDVKEEIGRGTFSVVRRAVHRTTGLEVAAKFVSRAG--GRRSEAQRELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIKE------------VKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQPVSTATD----------------------ICLSGTSPFLGENDRGTLMRVREGRFSLE--RCFSALSAEAGSFIARLLAVDP</Hsp_qseq>
      <Hsp_hseq>DFSIIDEVVGQGAFATVKKAIERTTGKTFAVKIISKRKVIGNMDGVTRELEVLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAK-VQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGPLKDFR-ISEEARDFIDSLLQVDP</Hsp_hseq>
      <Hsp_midline>D+  + E +G+G F+ V++A+ RTTG   A K +S+    G      REL +L +++HPR+  L+  ++      ++ E  SG +L+D +    A+ E       RQIL  + Y+H  G+ H D+K             VK+ D G A+ +   G    +  GT  +VAPE++  +  S + D                      + L+G  PF G        ++  G +     + F  +S EA  FI  LL VDP</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>1.97263e-10</Hsp_evalue>
      <Hsp_query-from>5731</Hsp_query-from>
      <Hsp_query-to>6324</Hsp_query-to>
      <Hsp_hit-from>209</Hsp_hit-from>
      <Hsp_hit-to>420</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>215</Hsp_align-len>
      <Hsp_qseq>FGVIRECKENATGRVFTAKIVPLEAASRAL--ALHEYEVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIV--SDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKG-DAVGAP------------ADVWGLAVLTFVLLSGESPFLGANDEETEKNI</Hsp_qseq>
      <Hsp_hseq>FATVKKAIERTTGKTFAVKIISKRKVIGNMDGVTRELEVLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKV---QGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQI</Hsp_hseq>
      <Hsp_midline>F  +++  E  TG+ F  KI+        +     E EVL+ L    I+ L   Y       ++ E   G +L   +       ED       Q+L A+ Y+H   I H D+K DN+++   D   +K+ DFG A+     G    +    GTL + APE+++G D   +P             D+W +  L +V+L+G  PF G+  ++  K I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>94.3597</Hsp_bit-score>
      <Hsp_score>233</Hsp_score>
      <Hsp_evalue>7.49369e-20</Hsp_evalue>
      <Hsp_query-from>1654</Hsp_query-from>
      <Hsp_query-to>2307</Hsp_query-to>
      <Hsp_hit-from>55</Hsp_hit-from>
      <Hsp_hit-to>291</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>242</Hsp_align-len>
      <Hsp_qseq>YDVKEEIGRGTFSVVRRAVHRTTGLEVAAKFVSRAGGRRSEAQ----RELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQPVST-ATDICLSGTS---------PFLGENDRGTLMRVREGRFSLERCFSALSAEAGSFIARLLAVDP</Hsp_qseq>
      <Hsp_hseq>YQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSN-IMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKF---LSPGAAGLIKRMLIVNP</Hsp_hseq>
      <Hsp_midline>Y + + +G G+F  V+ A H TTG +VA K +++    +S+ Q    RE+  L  + HP +  L D  +++  +I++ E   G EL D +V++  +SE +   + +QI+  V Y H+  ++H D+K           VK+ D G +  +M  G    ++ G+P + APE++  +  +    D+   G           PF  E+       +  G ++L +    LS  A   I R+L V+P</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>4.17899e-11</Hsp_evalue>
      <Hsp_query-from>5731</Hsp_query-from>
      <Hsp_query-to>6288</Hsp_query-to>
      <Hsp_hit-from>66</Hsp_hit-from>
      <Hsp_hit-to>252</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>191</Hsp_align-len>
      <Hsp_qseq>FGVIRECKENATGRVFTAKIVPLEAASRALAL----HEYEVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAVGAP-ADVWGLAVLTFVLLSGESPF</Hsp_qseq>
      <Hsp_hseq>FGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNF---LKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPF</Hsp_hseq>
      <Hsp_midline>FG ++      TG+    KI+  +  +++        E   L+ LR  HI+ L++   +   ++++ E   G ELF  +++  + +E +   +  Q++ A+ Y H   IVH D+K +NL++ +   +K+ DFG +           +    G+  ++APE++ G     P  DVW   V+ +V+L    PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.5893</Hsp_bit-score>
      <Hsp_score>231</Hsp_score>
      <Hsp_evalue>2.85721e-19</Hsp_evalue>
      <Hsp_query-from>1780</Hsp_query-from>
      <Hsp_query-to>2307</Hsp_query-to>
      <Hsp_hit-from>162</Hsp_hit-from>
      <Hsp_hit-to>354</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>197</Hsp_align-len>
      <Hsp_qseq>QRELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK-----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQPVSTA-TDI---------CLSGTSPFLGENDRGTLMRVREGRFSLERCFSALSAEAGSFIARLLAVDP</Hsp_qseq>
      <Hsp_hseq>EREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAA-LELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMP---SNLSSEARDLISKILVIDP</Hsp_hseq>
      <Hsp_midline>+RE+ I+  +SH  +  L + ++ +  L ++ E   G EL D LV K  + E +   Y +QI+EGV Y H   + H D+K            +K+ D G A  L  P +   ++ G+P + +PEIV+ +P     +D+          L+G  PF  +N +  L++V+ G++ +    S LS+EA   I+++L +DP</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>72.7886</Hsp_bit-score>
      <Hsp_score>177</Hsp_score>
      <Hsp_evalue>5.87418e-13</Hsp_evalue>
      <Hsp_query-from>5830</Hsp_query-from>
      <Hsp_query-to>6402</Hsp_query-to>
      <Hsp_hit-from>164</Hsp_hit-from>
      <Hsp_hit-to>350</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>193</Hsp_align-len>
      <Hsp_qseq>EYEVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIV-SDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAV-GAPADVWGLAVLTFVLLSGESPFLGANDEETEKNIRQCRPDITRCYVNVSQTALFFLRRLM</Hsp_qseq>
      <Hsp_hseq>EIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPN---KLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPF---NDDNIKKLLLKVQSGKYQMPSNLSSEARDLISKIL</Hsp_hseq>
      <Hsp_midline>E  ++K +   ++M L E +     L L+ E   G ELF  L+   +  E + + Y  Q++  ++Y H  +I H D+K +NL++   +R++K+ DFG A    P+   + +    G+  +++PE+V G    G P+DVW   ++ F LL+G  PF   ND+  +K + + +    +   N+S  A   + +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>91.6633</Hsp_bit-score>
      <Hsp_score>226</Hsp_score>
      <Hsp_evalue>8.23679e-19</Hsp_evalue>
      <Hsp_query-from>1654</Hsp_query-from>
      <Hsp_query-to>2307</Hsp_query-to>
      <Hsp_hit-from>21</Hsp_hit-from>
      <Hsp_hit-to>270</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>252</Hsp_align-len>
      <Hsp_qseq>YDVKEEIGRGTFSVVRRAVHRTTGLEVAAKFVSRA----GGRRSE--------AQRELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQPVST-ATDI---------CLSGTSPFLGEND--RGTLMRVREGRFSLERCFSALSAEAGSFIARLLAVDP</Hsp_qseq>
      <Hsp_hseq>WKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAA-LQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPND-TEISRDAQDLIGKILVVDP</Hsp_hseq>
      <Hsp_midline>+ + E +G G+   V+ A H  TG   A K +S++     G  S          +RE+ I+  +SHP +  L D ++T   L ++ E     EL + LV    + E +     RQI+ G+ Y H  G++H D+K           +K+ D G A  L        ++ G+P + APEIV   P    A+D+          L+G  PF  EN   R  L++V++G+F +    + +S +A   I ++L VDP</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>4.05116e-10</Hsp_evalue>
      <Hsp_query-from>5830</Hsp_query-from>
      <Hsp_query-to>6333</Hsp_query-to>
      <Hsp_hit-from>77</Hsp_hit-from>
      <Hsp_hit-to>237</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>169</Hsp_align-len>
      <Hsp_qseq>EYEVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAV-GAPADVWGLAVLTFVLLSGESPFLGANDEETEKNIRQC</Hsp_qseq>
      <Hsp_hseq>EIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMA---ALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPF-----DEENGNVRDL</Hsp_hseq>
      <Hsp_midline>E  ++K L   +++ L++ + T   L LI E     ELF  L++     E + +    Q+++ ++Y H   IVH D+K +NL++     +K+ DFG A   A       +    G+  ++APE+V G    G  +DVW   V+ F LL+G  PF     +E   N+R  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.5817</Hsp_bit-score>
      <Hsp_score>218</Hsp_score>
      <Hsp_evalue>3.68113e-18</Hsp_evalue>
      <Hsp_query-from>1648</Hsp_query-from>
      <Hsp_query-to>2181</Hsp_query-to>
      <Hsp_hit-from>198</Hsp_hit-from>
      <Hsp_hit-to>421</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>54</Hsp_gaps>
      <Hsp_align-len>228</Hsp_align-len>
      <Hsp_qseq>DYYDVKEEIGRGTFSVVRRAVHRTTGLEVAAKFVSRAGGRRSEAQRELR----ILARVSHPRLACLRDAF------QTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK-----------------------------EVKLCDLGSAQELMPPGQPQYSAT--GTPEFVAPEIVLQQPVSTATD---------ICLSGTSPF</Hsp_qseq>
      <Hsp_hseq>DKYLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGE-LFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAK---FTGEMQFTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVILYVCLCGFPPF</Hsp_hseq>
      <Hsp_midline>D Y + +E+G G +++V+ A ++ TG +VA K          +  ++ R    IL RV HP +  L D+F         ++ ++L ++  GE L +R+V+K  + + +     +Q+L G+ YLH+  ++H DIK                             +VK+ D G A+     G+ Q++ T  GTP +VAPE++ ++  ++  D         +CL G  PF</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>3.06576e-09</Hsp_evalue>
      <Hsp_query-from>5731</Hsp_query-from>
      <Hsp_query-to>6288</Hsp_query-to>
      <Hsp_hit-from>211</Hsp_hit-from>
      <Hsp_hit-to>421</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>216</Hsp_align-len>
      <Hsp_qseq>FGVIRECKENATGRVFTAKIVPLEAASRALALHEY----EVLKALRQEHIMGLHEAYVTP-------RYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRK-------------------LKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPF</Hsp_qseq>
      <Hsp_hseq>YALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVL--EKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKF---TGEMQFTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVILYVCLCGFPPF</Hsp_hseq>
      <Hsp_midline>+ +++E K   TG+    KI   +         ++     +L  ++  +I+ L +++V P       +YLVL  E+    ELF +++      +D+      QLL  L YLHE++I+H DIK +N++++ +R+                   +K+ DFG A+    +G  +      GT  + APE++      +  D+W   V+ +V L G  PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.8113</Hsp_bit-score>
      <Hsp_score>216</Hsp_score>
      <Hsp_evalue>1.59614e-17</Hsp_evalue>
      <Hsp_query-from>1654</Hsp_query-from>
      <Hsp_query-to>2307</Hsp_query-to>
      <Hsp_hit-from>19</Hsp_hit-from>
      <Hsp_hit-to>274</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>258</Hsp_align-len>
      <Hsp_qseq>YDVKEEIGRGTFSVVRRAVHRTTGLEVAAKFVSRA-------------GGRRSEA-----QRELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQPVST-ATDI---------CLSGTSPFLGE--NDRGTLMRVREGRFSLERCFSALSAEAGSFIARLLAVDP</Hsp_qseq>
      <Hsp_hseq>WKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAA-LETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMP-SDDEISREAQDLIRKILTVDP</Hsp_hseq>
      <Hsp_midline>+ + E +G G+   V+ A + +TG E A K +S+A             G    +A     +RE+ I+  ++HP +  L D ++T   L ++ E     EL + LV++  + E +   + RQI+ GV Y H  G++H D+K           +K+ D G A  L   G+   ++ G+P + APEIV   P    A+D+          L+G  PF  E  N R  L++V++G F +      +S EA   I ++L VDP</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>1.82585e-10</Hsp_evalue>
      <Hsp_query-from>5839</Hsp_query-from>
      <Hsp_query-to>6327</Hsp_query-to>
      <Hsp_hit-from>84</Hsp_hit-from>
      <Hsp_hit-to>239</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>164</Hsp_align-len>
      <Hsp_qseq>VLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAV-GAPADVWGLAVLTFVLLSGESPFLGANDEETEKNIR</Hsp_qseq>
      <Hsp_hseq>IMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMA---ALETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPF-----DEEDGNIR</Hsp_hseq>
      <Hsp_midline>++K L   +++ L++ + T   L L+ E     ELF  L+E     E + + +  Q+++ ++Y H   IVH D+K +NL++     +K+ DFG A   A     + +    G+  ++APE+V G    G  +DVW   V+ F LL+G  PF     +E + NIR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.9518</Hsp_bit-score>
      <Hsp_score>193</Hsp_score>
      <Hsp_evalue>5.63539e-15</Hsp_evalue>
      <Hsp_query-from>1654</Hsp_query-from>
      <Hsp_query-to>2307</Hsp_query-to>
      <Hsp_hit-from>412</Hsp_hit-from>
      <Hsp_hit-to>652</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>246</Hsp_align-len>
      <Hsp_qseq>YDVKEEIGRGTF----SVVRRAVHRTTGLEVAAKFVSRAGGRRSEAQRELRIL---ARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQPVSTAT-----------DICLSGTSPFLGENDRGTLMRVREGRFSLERCFSALSAEAGSFIARLLAVDP</Hsp_qseq>
      <Hsp_hseq>FEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTF--CGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCC-GWSPFFAENNQKMYQKIAFGKVKFPR--DVLSQEGRSFVKGLLNRNP</Hsp_hseq>
      <Hsp_midline>++V   +G+GTF     V ++   R   ++V +K V       +    E  IL   A  S P +  L+ +FQT   L ++T+  SG EL   L K+   SE +   YI +++  + +LH + +++ D+K           + LCD G ++  +      +   GT E++APE++L +   T             ++C  G SPF  EN++    ++  G+    R    LS E  SF+  LL  +P</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>75.8702</Hsp_bit-score>
      <Hsp_score>185</Hsp_score>
      <Hsp_evalue>5.44333e-14</Hsp_evalue>
      <Hsp_query-from>5731</Hsp_query-from>
      <Hsp_query-to>6324</Hsp_query-to>
      <Hsp_hit-from>423</Hsp_hit-from>
      <Hsp_hit-to>624</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>216</Hsp_align-len>
      <Hsp_qseq>FGVIRECKENATGRVFTAKIVPLEAASRALALHEYEVLKALRQEHIM------------GLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRT----GTLEHSAPEMVKGDAVGAP--ADVWGLAVLTFVLLSGESPFLGANDEETEKNI</Hsp_qseq>
      <Hsp_hseq>FGQVYQVKKKDTQRIYAMKVL-----SKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKA--------DLKDRTNTFCGTTEYLAPELLL-DETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKI</Hsp_hseq>
      <Hsp_midline>FG + + K+  T R++  K++     S+ + + + E+   + + +I+            GL  ++ TP  L L+ +   G ELF+ L +  R++ED    Y+++L+LAL +LH+  IV+ D+K +N+++  +  + L DFG +++         +  RT    GT E+ APE++  D  G     D W L VL F +  G SPF   N+++  + I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.9518</Hsp_bit-score>
      <Hsp_score>193</Hsp_score>
      <Hsp_evalue>6.00718e-15</Hsp_evalue>
      <Hsp_query-from>1672</Hsp_query-from>
      <Hsp_query-to>2307</Hsp_query-to>
      <Hsp_hit-from>88</Hsp_hit-from>
      <Hsp_hit-to>322</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>237</Hsp_align-len>
      <Hsp_qseq>IGRGTFSVVRRAVHRTTGLEVAAKFVSRAGGRRSEAQR----ELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQPVSTATDI-----------CLSGTSPFLGENDRGTLMRVREGRFSLERCFSALSAEAGSFIARLLAVDP</Hsp_qseq>
      <Hsp_hseq>LGEGGFARCFQ-IKDDSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRD-KPISDEGKILIRDILSLDP</Hsp_hseq>
      <Hsp_midline>+G G F+   + +   +G   AAK V++A  +  + ++    E++I   +SHP +    D F+    + IL E+C    L++ L ++  ++E +V  +  QI   + Y+H   V+H D+K           +K+ D G A  L    + +Y+  GTP ++APE+++ +    + ++            L G  PF   +      R++   FS  R    +S E    I  +L++DP</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>4.98892e-11</Hsp_evalue>
      <Hsp_query-from>5755</Hsp_query-from>
      <Hsp_query-to>6336</Hsp_query-to>
      <Hsp_hit-from>100</Hsp_hit-from>
      <Hsp_hit-to>296</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>200</Hsp_align-len>
      <Hsp_qseq>ENATGRVFTAKIVPLEA----ASRALALHEYEVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAVGAP--ADVWGLAVLTFVLLSGESPFLGANDEETEKNIRQCR</Hsp_qseq>
      <Hsp_hseq>KDDSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTI--CGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPF-QARDVNTIYERIKCR</Hsp_hseq>
      <Hsp_midline>++ +G +F AK V   +     +R   L E ++ K++   +I+   + +     + ++ E CP   L   L      TE +V  + +Q+  A+ Y+H R ++H D+K  N+    +  LK+ DFG A   A     +  +   GT  + APE++ G   G     D+W L V+ + LL G+ PF  A D  T     +CR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YMR291W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:852630:854390:1 gene:YMR291W transcript:YMR291W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TDA1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000004905]</Hit_def>
  <Hit_accession>YMR291W</Hit_accession>
  <Hit_len>586</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.0258</Hsp_bit-score>
      <Hsp_score>188</Hsp_score>
      <Hsp_evalue>1.82872e-14</Hsp_evalue>
      <Hsp_query-from>5731</Hsp_query-from>
      <Hsp_query-to>6333</Hsp_query-to>
      <Hsp_hit-from>50</Hsp_hit-from>
      <Hsp_hit-to>307</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>59</Hsp_gaps>
      <Hsp_align-len>259</Hsp_align-len>
      <Hsp_qseq>FGVIRECKENATGRVFTAKIVPLEAASRALAL--HEYEVLKALRQE-------------------HIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYT-EDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLI----VSDSRK------------------LKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKG--------------DAVGAPADVWGLAVLTFVLLSGESPFLGANDEETEKNIRQC</Hsp_qseq>
      <Hsp_hseq>FSVVKECMNIHTKDLYAMKLIKKQTVKNKIQLIQREFDLLRSISEKIRDMEKKNEHSLDIFEGHHHILQLFDYFETADNIVLITQLCQKGDLYEKIVENQCLDLETQVTSYCACLVSVLEFLHSQGIVHRDLKAENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLVLADFGLAAEYNTSKV-NSLKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGCPVDIWALGVLTYFMAFGYTPFDCTTDDETLECISKC</Hsp_hseq>
      <Hsp_midline>F V++EC    T  ++  K++  +     + L   E+++L+++ ++                   HI+ L + + T   +VLI + C   +L+ K++E+     E  V  Y + L+  L +LH + IVH D+K++N++    V+++ K                  L L DFG A  +  S     +    GT+ + APE+VK               D  G P D+W L VLT+ +  G +PF    D+ET + I +C</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>58.5362</Hsp_bit-score>
      <Hsp_score>140</Hsp_score>
      <Hsp_evalue>9.83784e-09</Hsp_evalue>
      <Hsp_query-from>1597</Hsp_query-from>
      <Hsp_query-to>2019</Hsp_query-to>
      <Hsp_hit-from>24</Hsp_hit-from>
      <Hsp_hit-to>182</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>163</Hsp_align-len>
      <Hsp_qseq>LSVSQADCGVYTLRTVSDYYDVKEEIGRGTFSVVRRAVHRTTGLEVAAKFVSR--AGGRRSEAQRELRILARVS-------------------HPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAIS-ELQVHPYIRQILEGVHYLHQSGVLHLDIK</Hsp_qseq>
      <Hsp_hseq>LSGSNADAQTFKCKYVTNH----NSLGDGNFSVVKECMNIHTKDLYAMKLIKKQTVKNKIQLIQREFDLLRSISEKIRDMEKKNEHSLDIFEGHHHILQLFDYFETADNIVLITQLCQKGDLYEKIVENQCLDLETQVTSYCACLVSVLEFLHSQGIVHRDLK</Hsp_hseq>
      <Hsp_midline>LS S AD   +  + V+++      +G G FSVV+  ++  T    A K + +     +    QRE  +L  +S                   H  +  L D F+T   ++++T+LC   +L +++V+   +  E QV  Y   ++  + +LH  G++H D+K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.0258</Hsp_bit-score>
      <Hsp_score>188</Hsp_score>
      <Hsp_evalue>2.52077e-14</Hsp_evalue>
      <Hsp_query-from>1654</Hsp_query-from>
      <Hsp_query-to>2157</Hsp_query-to>
      <Hsp_hit-from>25</Hsp_hit-from>
      <Hsp_hit-to>201</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>181</Hsp_align-len>
      <Hsp_qseq>YDVKEEIGRGTFSVVRRAVHRTTGLEVAAKFVSRAGGRR-SEAQRELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPA--ISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQPVSTATDI</Hsp_qseq>
      <Hsp_hseq>YHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSL-RRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIV---NSSALTLAGTLNWMAPEILGNRGASTLSDI</Hsp_hseq>
      <Hsp_midline>Y +K+ IGRG++ VV +A+++ T   VA K V        ++   E+ +L  ++H  +       +    L IL E C+   L  RL+ + +  +SE +   Y+ Q L G+ YLH  GV+H DIK           VKL D G +  +        +  GT  ++APEI+  +  ST +DI</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>4.66878e-06</Hsp_evalue>
      <Hsp_query-from>5731</Hsp_query-from>
      <Hsp_query-to>6303</Hsp_query-to>
      <Hsp_hit-from>36</Hsp_hit-from>
      <Hsp_hit-to>223</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>195</Hsp_align-len>
      <Hsp_qseq>FGVIRECKENATGRVFTAKIVPLEAASRALALH-EYEVLKALRQEHIMGLHEAYVTPRY-LVLIAERCPGKELFYKLLE--SPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPFLGAND</Hsp_qseq>
      <Hsp_hseq>YGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNHNNIVKYH-GFIRKSYELYILLEYCANGSL-RRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSA-----LTLAGTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNPPYHNLTD</Hsp_hseq>
      <Hsp_midline>+GV+ +     T +V   K V  E       +  E  +LK L   +I+  H  ++   Y L ++ E C    L  +L+   S   +E++   Y++Q LL L YLH   ++H DIK+ N+++S    +KL DFG +     S      +   GTL   APE++        +D+W L      +L+   P+    D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.485</Hsp_bit-score>
      <Hsp_score>184</Hsp_score>
      <Hsp_evalue>4.07779e-14</Hsp_evalue>
      <Hsp_query-from>1633</Hsp_query-from>
      <Hsp_query-to>2304</Hsp_query-to>
      <Hsp_hit-from>155</Hsp_hit-from>
      <Hsp_hit-to>428</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>56</Hsp_gaps>
      <Hsp_align-len>277</Hsp_align-len>
      <Hsp_qseq>LRTVSDYYDVKEEIGRGTFS---VVRRAVHRTTGL-----EVAAKFVSRAGGRRSEAQRELRILARVSHPRLACLRDAFQTRRR-LIILTELCSGEELLDRLVKK---PAISELQVHPYIRQILEGVHYLHQSGVLHLDIK--EVKLC-----------DLGSAQELMPPGQPQYSATGTPEFVAPEI----------------VLQQ----------PVSTATDICLSGTSPFLGE-NDRGTLMRVREGRFSLE-RCFSALSAEAGSFIARLLAVD</Hsp_qseq>
      <Hsp_hseq>LREVDQWEITNRIVGNGTFGHVLITHNSKERDEDVCYHPENYAVKIIKL---KPNKFDKEARILLRLDHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGISPFYGDGSERSIIQNAKIGKLNFKLKQWDIVSDNAKSFVKDLLQTD</Hsp_hseq>
      <Hsp_midline>LR V  +      +G GTF    +   +  R   +       A K +     + ++  +E RIL R+ HP +  +   F  R   L I  +L  G +L   L K     ++SE +    + QIL+ ++YLH   ++H D+K   + LC           D G A++L    +  ++  GTPE+ APE+                 L+Q           +   T I L+G SPF G+ ++R  +   + G+ + + + +  +S  A SF+  LL  D</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>8.62355e-07</Hsp_evalue>
      <Hsp_query-from>5830</Hsp_query-from>
      <Hsp_query-to>6312</Hsp_query-to>
      <Hsp_hit-from>211</Hsp_hit-from>
      <Hsp_hit-to>393</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>185</Hsp_align-len>
      <Hsp_qseq>EYEVLKALRQEHIMGLHEAYVT-PRYLVLIAERCPGKELFYKLLESPRYT---EDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSR---KLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEM-----------------VKGDAVGAPADVWGLAVLTFVLLSGESPFLGANDEET</Hsp_qseq>
      <Hsp_hseq>EARILLRLDHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKERMHTV--VGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGISPFYGDGSERS</Hsp_hseq>
      <Hsp_midline>E  +L  L   +I+ ++  +     +L +  +  PG +LF  L +    T   E + +  + Q+L AL YLH++ IVH D+K DN+++       ++ L DFG A+    +      V   GT E+ APE+                 ++     +  D+W L V+T ++L+G SPF G   E +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>3.2408e-13</Hsp_evalue>
      <Hsp_query-from>1621</Hsp_query-from>
      <Hsp_query-to>2229</Hsp_query-to>
      <Hsp_hit-from>63</Hsp_hit-from>
      <Hsp_hit-to>281</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>226</Hsp_align-len>
      <Hsp_qseq>GVYTLRTVSDYYDVKEEIGRGTFSVVR--RAVH--RTTGLEVAAKFVSRAGGRRSEAQRELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQPVSTATDI---------CLSGTSPFLGENDRGTLMRVREGR</Hsp_qseq>
      <Hsp_hseq>GKYTLHD----FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQ---TVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGK</Hsp_hseq>
      <Hsp_midline>G YTL      + +   +G G+F  V   R+VH  R   ++V  K       +      E R+L  V HP L  +   FQ  R + ++ +   G EL   L K           Y  +++  + YLH   +++ D+K           +K+ D G A+E+       ++  GTP+++APE++  +P + + D           L+G +PF       T  ++ +G+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>1.04444e-09</Hsp_evalue>
      <Hsp_query-from>5731</Hsp_query-from>
      <Hsp_query-to>6336</Hsp_query-to>
      <Hsp_hit-from>81</Hsp_hit-from>
      <Hsp_hit-to>281</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>208</Hsp_align-len>
      <Hsp_qseq>FGVIRECKENATGRVFTAKIVPLEAASRALALH----EYEVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRT--GTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPFLGANDEETEKNIRQCR</Hsp_qseq>
      <Hsp_hseq>FGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQ-------TVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGK</Hsp_hseq>
      <Hsp_midline>FG +   +    GR +  K++  +   +   +     E  +LK +    ++ +   +   R + ++ +   G ELF  L +S R+       Y ++++LAL YLH  +I++ D+K +N+++  +  +K+ DFG A+           V  T  GT ++ APE++         D W L VL + +L+G +PF      +T + I Q +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>4.30068e-13</Hsp_evalue>
      <Hsp_query-from>6031</Hsp_query-from>
      <Hsp_query-to>6426</Hsp_query-to>
      <Hsp_hit-from>967</Hsp_hit-from>
      <Hsp_hit-to>1091</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>HERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAV-GAPADVWGLAVLTFVLLSGESPFLGANDEETEKNIRQCRPDITRCYVNVSQTALFFLRRLMT---QRRSTVS</Hsp_qseq>
      <Hsp_hseq>HDQGIVHRDIKDENVIVDSHGFVKLIDFGSA-AYIKSG---PFDVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLYTIIYKENPYYNI-DEILEGELRFDKSE------HVSEECISLIKRILTREVDKRPTID</Hsp_hseq>
      <Hsp_midline>H++ IVH DIK +N+IV     +KL+DFGSA ++  SG   P     GT++++APE++ G +  G P D+W L VL + ++  E+P+    DE  E  +R  + +      +VS+  +  ++R++T    +R T+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.8626</Hsp_bit-score>
      <Hsp_score>172</Hsp_score>
      <Hsp_evalue>9.0992e-13</Hsp_evalue>
      <Hsp_query-from>1630</Hsp_query-from>
      <Hsp_query-to>2169</Hsp_query-to>
      <Hsp_hit-from>15</Hsp_hit-from>
      <Hsp_hit-to>204</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>196</Hsp_align-len>
      <Hsp_qseq>TLRTVSDYYDVKEEIGRGTFSVVRRAVHRTTGLEVAAK-----FVSRAGGRRSEAQRELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQ-QPVSTATDICLSG</Hsp_qseq>
      <Hsp_hseq>TVFEITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRT--YRELKLLKHLRHENLICLQDIFLSPLEDIYFVTELQGTDL-HRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLAR-IQDPQMTGYVSTRY--YRAPEIMLTWQKYDVEVDIWSAG</Hsp_hseq>
      <Hsp_midline>T+  +++ Y+    +G G F +V  A    T   VA K     F +    +R+   REL++L  + H  L CL+D F +    I       G +L  RL++   + +  V  ++ QIL G+ Y+H +GV+H D+K          ++K+CD G A+ +  P    Y +T    + APEI+L  Q      DI  +G</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>5.93771e-06</Hsp_evalue>
      <Hsp_query-from>5731</Hsp_query-from>
      <Hsp_query-to>6300</Hsp_query-to>
      <Hsp_hit-from>34</Hsp_hit-from>
      <Hsp_hit-to>221</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>194</Hsp_align-len>
      <Hsp_qseq>FGVIRECKENATGRVFTAKIVPLEAASRALALHEY---EVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPE-MVKGDAVGAPADVWGLAVLTFVLLSGESPFLGAN</Hsp_qseq>
      <Hsp_hseq>FGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLSPLEDIYFVTELQGTDL-HRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ-----MTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKD</Hsp_hseq>
      <Hsp_midline>FG++    +  T +    K +    ++  LA   Y   ++LK LR E+++ L + +++P   +       G +L ++LL++    +  V  +L Q+L  L Y+H   ++H D+K  N++++++  LK+ DFG AR   P      +     T  + APE M+         D+W    +   ++ G+  F G +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>9.31045e-13</Hsp_evalue>
      <Hsp_query-from>5770</Hsp_query-from>
      <Hsp_query-to>6300</Hsp_query-to>
      <Hsp_hit-from>590</Hsp_hit-from>
      <Hsp_hit-to>772</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>185</Hsp_align-len>
      <Hsp_qseq>RVFTAKIVPLEAASRALALHEYEVLKALRQEHIMGLHEAYV-TPRYLVLIAERCPGKELFYKLLESPR-------YTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPFLGAN</Hsp_qseq>
      <Hsp_hseq>KVAIKQMVLSKQPRKELIVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATM--VGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYLNED</Hsp_hseq>
      <Hsp_midline>+V   ++V  +   + L ++E  V+K  R ++I+   EAY+ T   L ++ E   G  L   +  SP         TE  +   + +    L +LH++HI+H DIKSDN+++    ++K+ DFG         + R  +   GT    APE+VK        DVW L ++T  +L GE P+L  +</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>1.7804e-08</Hsp_evalue>
      <Hsp_query-from>1723</Hsp_query-from>
      <Hsp_query-to>2304</Hsp_query-to>
      <Hsp_hit-from>588</Hsp_hit-from>
      <Hsp_hit-to>809</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>222</Hsp_align-len>
      <Hsp_qseq>GLEVAAK-FVSRAGGRRSEAQRELRILARVSHPRLACLRDAF-QTRRRLIILTELCSGEELLDRLVKKPA-------ISELQVHPYIRQILEGVHYLHQSGVLHLDIKE----------VKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQPVSTATDI---------CLSGTSPFLGENDRGTLMRVREGRFSLERCFSALSAEAGSFIARLLAVD</Hsp_qseq>
      <Hsp_hseq>GDKVAIKQMVLSKQPRKELIVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATNGTPKLKHPESLSLEIKRFLSVCLCVD</Hsp_hseq>
      <Hsp_midline>G +VA K  V     R+     E+ ++    H  +    +A+ +T   L ++ E   G  L D +   P        ++E Q+   +R+  +G+ +LH   ++H DIK           VK+ D G    L      + +  GTP ++APE+V Q+      D+          L G  P+L E+    L  +        +   +LS E   F++  L VD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>9.74417e-13</Hsp_evalue>
      <Hsp_query-from>5734</Hsp_query-from>
      <Hsp_query-to>6324</Hsp_query-to>
      <Hsp_hit-from>336</Hsp_hit-from>
      <Hsp_hit-to>554</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>221</Hsp_align-len>
      <Hsp_qseq>GVIRECKENATGRVFTAKIVP----LEAASRALALHEYEVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLL--ESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRT------------------GTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPFLGANDEETEKNI</Hsp_qseq>
      <Hsp_hseq>GKVYLVRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFD--LSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNI</Hsp_hseq>
      <Hsp_midline>G +   +E  T ++F  K++     ++       L E E+L       I+ L+ ++ T  YL L  E C G E F  L   +S    E+D   Y S+++ AL YLH    ++ D+K +N+++  S  + L DF    S   +G+ +P +  +                  GT E+ APE+++G+   A  D W L +L + +L G +PF G N  ET  NI</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>5.56108e-08</Hsp_evalue>
      <Hsp_query-from>1672</Hsp_query-from>
      <Hsp_query-to>2295</Hsp_query-to>
      <Hsp_hit-from>330</Hsp_hit-from>
      <Hsp_hit-to>579</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>253</Hsp_align-len>
      <Hsp_qseq>IGRGTFSVVRRAVHRTTGLEVAAKFVSRAGG-RRSEAQR---ELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLV--KKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDL-------GSAQELMP-----------PGQPQYSATGTPEFVAPEIVLQQPVSTATDI---------CLSGTSPFLGENDRGTLMRV--REGRFSLERCFSALSAEAGSFIARLL</Hsp_qseq>
      <Hsp_hseq>LGQGDVGKVYLVRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKFPHDK---EVSKNCKDLIKKLL</Hsp_hseq>
      <Hsp_midline>+G+G    V     R T    A K +++    +R + +R   E  ILA   HP +  L  +FQT+  L +  E C G E    L   K   I+E     Y  +++  + YLH  G ++ D+K           V L D        GS +  M             G    S  GT E++APE++     + A D           L G +PF G+N   T   +  ++ +F  ++    +S      I +LL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.3218</Hsp_bit-score>
      <Hsp_score>168</Hsp_score>
      <Hsp_evalue>1.02896e-12</Hsp_evalue>
      <Hsp_query-from>1666</Hsp_query-from>
      <Hsp_query-to>2208</Hsp_query-to>
      <Hsp_hit-from>11</Hsp_hit-from>
      <Hsp_hit-to>218</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>208</Hsp_align-len>
      <Hsp_qseq>EEIGRGTFSVVRRAVHRTTGLEVAAKFVSRAG--GRRSEAQRELRILARVSHPRLACLRDAFQTRRRLIILTELCSGE--ELLD-RLV-KKPAISELQVHPYIR-QILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVL-QQPVSTATDI---------CLSGTSPFLGENDRGTL</Hsp_qseq>
      <Hsp_hseq>EKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQL</Hsp_hseq>
      <Hsp_midline>E++G GT++ V + +++TTG+ VA K V      G  S A RE+ ++  + H  +  L D   T  +L ++ E    +  + +D R V   P   EL +  Y + Q+L+G+ + H++ +LH D+K          ++KL D G A+    P     S   T  + AP++++  +  ST+ DI          ++G   F G ND   L</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>4.00869e-11</Hsp_evalue>
      <Hsp_query-from>5731</Hsp_query-from>
      <Hsp_query-to>6324</Hsp_query-to>
      <Hsp_hit-from>18</Hsp_hit-from>
      <Hsp_hit-to>221</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>209</Hsp_align-len>
      <Hsp_qseq>FGVIRECKENATGRVFTAKIVPL--EAASRALALHEYEVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLES------PRYTEDDVVGXXX-XXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAP-RPIVPRTGTLEHSAPEMVKGD-AVGAPADVWGLAVLTFVLLSGESPFLGANDEETEKNI</Hsp_qseq>
      <Hsp_hseq>YATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDND--LKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAF---GIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLI</Hsp_hseq>
      <Hsp_midline>+  + +     TG     K V L  E  + + A+ E  ++K L+ E+I+ L++   T   L L+ E         K ++S      PR  E ++V Y   QLL  LA+ HE  I+H D+K  NL+++   +LKL DFG AR+F   G P         TL + AP+++ G        D+W    +   +++G+  F G NDEE  K I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>1.12611e-12</Hsp_evalue>
      <Hsp_query-from>1711</Hsp_query-from>
      <Hsp_query-to>2307</Hsp_query-to>
      <Hsp_hit-from>123</Hsp_hit-from>
      <Hsp_hit-to>340</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>222</Hsp_align-len>
      <Hsp_qseq>HRTTGLEVAAKFVSR----AGGRRSEAQRELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIKE----------VKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQPVSTATDI---------CLSGTSPFLGENDRGTLMRVREGRFSLERCFSALSAEAGSFIARLLAVDP</Hsp_qseq>
      <Hsp_hseq>HRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSI-INPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMP---SNISQDAQDLILKLLKYDP</Hsp_hseq>
      <Hsp_midline>HR+TG   A K + +        + + +RE+ I   ++HP L      F   +R+ +L E     E+   L      +++    YI QI   + Y+H+  ++H DIK           +KL D G +  + PP   + +  GT ++++PE+V  +      D           L+G  PF  E    T  R+      +    S +S +A   I +LL  DP</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>3.51058e-11</Hsp_evalue>
      <Hsp_query-from>6031</Hsp_query-from>
      <Hsp_query-to>6402</Hsp_query-to>
      <Hsp_hit-from>219</Hsp_hit-from>
      <Hsp_hit-to>336</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>124</Hsp_align-len>
      <Hsp_qseq>HERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPFLGANDEETEKNIRQCRPDITRCYVNVSQTALFFLRRLM</Hsp_qseq>
      <Hsp_hseq>HKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTVC---GTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAAL--DI-KMPSNISQDAQDLILKLL</Hsp_hseq>
      <Hsp_midline>H+++I+H DIK +N+++  +  +KL DFG +    P    + +    GT+++ +PEMV+        D W L VL F LL+G  PF     + T K I     DI +   N+SQ A   + +L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>3.21762e-12</Hsp_evalue>
      <Hsp_query-from>1672</Hsp_query-from>
      <Hsp_query-to>2250</Hsp_query-to>
      <Hsp_hit-from>185</Hsp_hit-from>
      <Hsp_hit-to>412</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>228</Hsp_align-len>
      <Hsp_qseq>IGRGTFSVVRRAVHRTTGLEVAAKFVSRAGGRRSEAQRELRI----LARVSH-PRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPG----QPQY-------SATGTPEFVAPEIVLQQPVSTATDI---------CLSGTSPFLGENDRGTLMRVREGRFSLERCF</Hsp_qseq>
      <Hsp_hseq>IGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKVQYAFTPGF</Hsp_hseq>
      <Hsp_midline>IG G +S V  A    T    AAK +++    R +  + + I    L ++++ P +  L   FQ    L  L E     + L  + K  ++ E     Y  QI++ + YLH +G++H DIK          ++KL D G+A+ L P      +P+Y       S  GT E+V+PE++         DI          ++G  PF   N+  T  +V + +++    F</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>6.83573e-09</Hsp_evalue>
      <Hsp_query-from>6031</Hsp_query-from>
      <Hsp_query-to>6303</Hsp_query-to>
      <Hsp_hit-from>295</Hsp_hit-from>
      <Hsp_hit-to>394</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>100</Hsp_align-len>
      <Hsp_qseq>HERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSG--APRP---IVPRT----GTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPFLGAND</Hsp_qseq>
      <Hsp_hseq>HSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNE</Hsp_hseq>
      <Hsp_midline>H   I+H DIK +N+++    K+KL DFG+A+   P+     +P   +  R+    GT E+ +PE++         D+W    + F +++G+ PF   N+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>3.28657e-12</Hsp_evalue>
      <Hsp_query-from>1648</Hsp_query-from>
      <Hsp_query-to>2193</Hsp_query-to>
      <Hsp_hit-from>342</Hsp_hit-from>
      <Hsp_hit-to>546</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>207</Hsp_align-len>
      <Hsp_qseq>DYYDVKEEIGRGTFSVVRRAVHRTTGLEVAAK------FVSRAGGRRSEAQRELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQPVSTATDI---------CLSGTSPFLGEN</Hsp_qseq>
      <Hsp_hseq>DDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERT--VLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDEN</Hsp_hseq>
      <Hsp_midline>D +D+ + IG+G+F  V +   + T    A K       VS+     + A+R   +LARV  P +  L+ +FQ+  +L ++    +G EL   L  +   S  +   YI ++L  +  LH+  V++ D+K           + LCD G  +  M       +  GTPE++APEI+L Q  +   D           ++G  P+  EN</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>9.38598e-08</Hsp_evalue>
      <Hsp_query-from>5731</Hsp_query-from>
      <Hsp_query-to>6330</Hsp_query-to>
      <Hsp_hit-from>344</Hsp_hit-from>
      <Hsp_hit-to>556</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>215</Hsp_align-len>
      <Hsp_qseq>FGVIRECKENATGRVF------TAKIVPLEAASRALALHEYEVLKALRQEHIMG---------LHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPFLGANDEETEKNIRQ</Hsp_qseq>
      <Hsp_hseq>FDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTF--CGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQ</Hsp_hseq>
      <Hsp_midline>F +++   + + G+V       T KI  L+A  +A  + + EV   L +  ++          L  ++ +P  L L+     G ELFY L    R++      Y+++LL AL  LH+  +++ D+K +N+++     + L DFG  +               GT E+ APE++ G       D W L +L + +++G  P+   N     K I Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.3218</Hsp_bit-score>
      <Hsp_score>168</Hsp_score>
      <Hsp_evalue>5.64879e-12</Hsp_evalue>
      <Hsp_query-from>1672</Hsp_query-from>
      <Hsp_query-to>2196</Hsp_query-to>
      <Hsp_hit-from>830</Hsp_hit-from>
      <Hsp_hit-to>1029</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>201</Hsp_align-len>
      <Hsp_qseq>IGRGTFSVV----RRAVHRTTGLEVAAK--FVSRAGGRRSEAQRELRILA-RVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQPVSTATDICLSGT---------SPFLGEND</Hsp_qseq>
      <Hsp_hseq>LGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWH-VQNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDE</Hsp_hseq>
      <Hsp_midline>+G+G F  V     +   R   ++V  K   +       + A++++ +LA +  HP L  L  +FQT  R+    E   G +L+   V+   +S  +   Y  ++L  + Y H +GV++ D+K           +K+ D G  ++ M  G    +  GTPEF+APEI+ +Q  + A D    G          SPF G+++</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>8.2488e-06</Hsp_evalue>
      <Hsp_query-from>6031</Hsp_query-from>
      <Hsp_query-to>6309</Hsp_query-to>
      <Hsp_hit-from>941</Hsp_hit-from>
      <Hsp_hit-to>1031</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>25</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>93</Hsp_align-len>
      <Hsp_qseq>HERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPFLGANDEE</Hsp_qseq>
      <Hsp_hseq>HDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTF--CGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDE</Hsp_hseq>
      <Hsp_midline>H+  +++ D+K +N++++    +K+ D+G  +     G         GT E  APE++K        D W   VL + +L  +SPF G +++E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>6.68755e-12</Hsp_evalue>
      <Hsp_query-from>5734</Hsp_query-from>
      <Hsp_query-to>6417</Hsp_query-to>
      <Hsp_hit-from>508</Hsp_hit-from>
      <Hsp_hit-to>759</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>121</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>257</Hsp_align-len>
      <Hsp_qseq>GVIRECKENATGRVFTAKIVPLEAASR----ALALHEYEVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYT---EDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVP-----------------RT----GTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPFLGANDEETEKNIRQCRPDITRCYVN-VSQTALFFLRRLMTQRRS</Hsp_qseq>
      <Hsp_hseq>GKVFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCMGGE-FFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDFD--LSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNI--LKNEVSFPNNNEISRTCKDLIKKLLTKNES</Hsp_hseq>
      <Hsp_midline>G +   +E  T RV+  K++  +   +       L E E+L       I+ L+ ++ +  YL L  E C G E F++ L++ +     EDD   Y S++  AL YLH    ++ D+K +N+++  S  + L DF    S     +  P+V                  RT    GT E+ APE+++G+   A  D W L +L + +L G +PF G N  ET  NI   + +++    N +S+T    +++L+T+  S</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>4.42409e-08</Hsp_evalue>
      <Hsp_query-from>1669</Hsp_query-from>
      <Hsp_query-to>2304</Hsp_query-to>
      <Hsp_hit-from>506</Hsp_hit-from>
      <Hsp_hit-to>757</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>256</Hsp_align-len>
      <Hsp_qseq>EIGRGTFSVVRRAVHRTTGLEVAAK--FVSRAGGRRSEAQRELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLV--KKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDL---------------GSAQ------ELMPPGQPQYSATGTPEFVAPEIVLQQPVSTATDI---------CLSGTSPFLGENDRGTLMRVREGRFSLERCFSALSAEAGSFIARLLAVD</Hsp_qseq>
      <Hsp_hseq>DVGK-VFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQE--ILATSNHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKNEVSFPNN-NEISRTCKDLIKKLLTKN</Hsp_hseq>
      <Hsp_midline>++G+  F V  +  +R   L+V +K   + R   +R   ++E  ILA  +HP +  L  +FQ+   L +  E C G E    L   K   I E     Y  ++   + YLH  G ++ D+K           + L D                GSAQ      ++   G    S  GT E++APE++     + A D           L G +PF G+N   T   + +   S     + +S      I +LL  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>7.42603e-12</Hsp_evalue>
      <Hsp_query-from>1666</Hsp_query-from>
      <Hsp_query-to>2307</Hsp_query-to>
      <Hsp_hit-from>129</Hsp_hit-from>
      <Hsp_hit-to>376</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>251</Hsp_align-len>
      <Hsp_qseq>EEIGRGTFSVVRRAVHRTTGLEVAAKFVSRAGGRRSEAQRELRI----LARVSHPR-LACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQEL------MPPGQPQY-------SATGTPEFVAPEIVLQQPVSTATDI---------CLSGTSPFLGENDRGTLMRVREGRFSLERCFSALSAEAGSFIARLLAVDP</Hsp_qseq>
      <Hsp_hseq>EQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQKLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKIQYAFTAGFPQIVKD---LVKKLLVRDP</Hsp_hseq>
      <Hsp_midline>E++G G++S V  A  R +G + A K +S+    R +  + + +    L +++  + +  L   FQ    L  L E     + L  + K  +++E     Y  QI++ V  LH  G++H DIK          +VKL D G+A+ L         G+P +       S  GT E+V+PE++      +  DI          L+G  PF   N+  T  +V + +++    F  +  +    + +LL  DP</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>1.3166e-08</Hsp_evalue>
      <Hsp_query-from>6031</Hsp_query-from>
      <Hsp_query-to>6303</Hsp_query-to>
      <Hsp_hit-from>241</Hsp_hit-from>
      <Hsp_hit-to>342</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>102</Hsp_align-len>
      <Hsp_qseq>HERHIVHLDIKSDNLIVSDSRKLKLVDFGSAR------SFAPSGAPR-PIVPRT----GTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPFLGAND</Hsp_qseq>
      <Hsp_hseq>HNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANE</Hsp_hseq>
      <Hsp_midline>H   I+H DIK +N+++  + K+KL DFG+A+      S    G P   +  ++    GT E+ +PE++  +   +  D+W    + + +L+G+ PF  AN+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>7.60513e-12</Hsp_evalue>
      <Hsp_query-from>1729</Hsp_query-from>
      <Hsp_query-to>2127</Hsp_query-to>
      <Hsp_hit-from>76</Hsp_hit-from>
      <Hsp_hit-to>223</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>148</Hsp_align-len>
      <Hsp_qseq>EVAAKFVSR---AGGRRSEAQ--RELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVL</Hsp_qseq>
      <Hsp_hseq>QVAIKLIKRDSISNDYRKEVKIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVNEFCSRNELMKTSCGSPCYAAPELVI</Hsp_hseq>
      <Hsp_midline>+VA K + R   +   R E +  RE+  L  +SHP +  L +  Q  R + I+ E   G E    + KK  + E+       Q++ GVHY+H  G++H D+K           + + D G   E     +   ++ G+P + APE+V+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>1.14849e-07</Hsp_evalue>
      <Hsp_query-from>5830</Hsp_query-from>
      <Hsp_query-to>6387</Hsp_query-to>
      <Hsp_hit-from>100</Hsp_hit-from>
      <Hsp_hit-to>278</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>191</Hsp_align-len>
      <Hsp_qseq>EYEVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRT--GTLEHSAPEMV-KGDAVGA-PADVWGLAVLTFVLLSGESPF-LGANDEETEKNIRQCRPDITRCYVNVSQTALFF</Hsp_qseq>
      <Hsp_hseq>EINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVNEF----CSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPWDDDPNNPEGS--------DIGRLYNYINSTPLKF</Hsp_hseq>
      <Hsp_midline>E   LK L   +I+ L E     RY+ ++ E   G E +  + +  R  E +     SQL+  + Y+H + +VH D+K +NL++  +  L + DFG    F      R  + +T  G+  ++APE+V   +   A  AD+W   V+ + +L+G  P+    N+ E          DI R Y  ++ T L F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.5514</Hsp_bit-score>
      <Hsp_score>166</Hsp_score>
      <Hsp_evalue>9.12095e-12</Hsp_evalue>
      <Hsp_query-from>5821</Hsp_query-from>
      <Hsp_query-to>6336</Hsp_query-to>
      <Hsp_hit-from>191</Hsp_hit-from>
      <Hsp_hit-to>360</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>173</Hsp_align-len>
      <Hsp_qseq>ALHEYEVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAVGAP-ADVWGLAVLTFVLLSGESPFLGANDEETEKNIRQCR</Hsp_qseq>
      <Hsp_hseq>TIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIY---DSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKIKQGK</Hsp_hseq>
      <Hsp_midline> + E  + + L   HI  L E      +  ++ E   G +L   +++     E     +   +  AL YLH  +IVH D+K +N+++SDS ++K++DFG +  +    + + +    G+L  +APE++K +    P  DVW   V+ FVL+ G+ PF   N     + I+Q +</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>1.77812e-11</Hsp_evalue>
      <Hsp_query-from>1597</Hsp_query-from>
      <Hsp_query-to>2307</Hsp_query-to>
      <Hsp_hit-from>102</Hsp_hit-from>
      <Hsp_hit-to>383</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>120</Hsp_positive>
      <Hsp_gaps>55</Hsp_gaps>
      <Hsp_align-len>287</Hsp_align-len>
      <Hsp_qseq>LSVSQADCGVYTLRTVSDYYDVKEEIGRGTFSVVRRAVHRTTGLEVAAKFVSRAGG--------------------RRSEAQREL----RILARVS------HPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQPVS----------TATDICLSGTSPFLGENDRGTLMRVREGRFSLERCFSALSAEAGSFIARLLAVDP</Hsp_qseq>
      <Hsp_hseq>VSSSQGMPKQFHRKSLGDWEFV-ETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPPPKNEQDVLERQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSN-IYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKIKQGKVEYPQ---HLSIEVISLLSKMLVVDP</Hsp_hseq>
      <Hsp_midline>+S SQ     +  +++ D+  V E +G G+   V+ A HR T    A K V+RA                      R+ + ++E+    R +   S      HP +  L +         +L E  SG +LLD +++  +I E Q   + R I   + YLH + ++H D+K          E+K+ D G +  +    +  ++  G+  F APE++   P +              + + G  PF  EN      ++++G+    +    LS E  S ++++L VDP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>1.83554e-11</Hsp_evalue>
      <Hsp_query-from>5731</Hsp_query-from>
      <Hsp_query-to>6324</Hsp_query-to>
      <Hsp_hit-from>99</Hsp_hit-from>
      <Hsp_hit-to>295</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>204</Hsp_align-len>
      <Hsp_qseq>FGVIRECKENATGRVFTAK------IVPLEAASRALALHEYEVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPFLGANDEETEKNI</Hsp_qseq>
      <Hsp_hseq>FGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTND--ERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKY-----VPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENI</Hsp_hseq>
      <Hsp_midline>FG +   + N  GR +  K      IV L+         E  +L  +    I+ +   +   + + ++ +   G ELF  L +S R+       Y +++ LAL YLH + I++ D+K +N+++  +  +K+ DFG A+       P       GT ++ APE+V         D W   VL + +L+G +PF  +N  +T +NI</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>6.46312e-11</Hsp_evalue>
      <Hsp_query-from>1621</Hsp_query-from>
      <Hsp_query-to>2304</Hsp_query-to>
      <Hsp_hit-from>81</Hsp_hit-from>
      <Hsp_hit-to>321</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>251</Hsp_align-len>
      <Hsp_qseq>GVYTLRTVSDYYDVKEEIGRGTFSVVR--RAVH--RTTGLEVAAKFVSRAGGRRSEAQRELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQPVSTATDI---------CLSGTSPFLGENDRGTLMRVREGRFSLERCFSALSAEAGSFIARLLAVD</Hsp_qseq>
      <Hsp_hseq>GKYSL---SDF-QILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYV---PDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFF---HPDAQDLLKKLITRD</Hsp_hseq>
      <Hsp_midline>G Y+L   SD+  +   +G G+F  V   R+ H  R   L+   K       +      E R+L+ VSHP +  +   FQ  +++ ++ +   G EL   L K           Y  ++   + YLH   +++ D+K           +K+ D G A+ +       Y+  GTP+++APE+V  +P + + D           L+G +PF   N   T   +          F     +A   + +L+  D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>2.63662e-11</Hsp_evalue>
      <Hsp_query-from>1642</Hsp_query-from>
      <Hsp_query-to>2130</Hsp_query-to>
      <Hsp_hit-from>19</Hsp_hit-from>
      <Hsp_hit-to>193</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>176</Hsp_align-len>
      <Hsp_qseq>VSDYYDVKEEIGRGTFSVVRRAVHRTTGLEVAAKFVS--RAGGRRSEAQRELRILARVSH-PRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQ</Hsp_qseq>
      <Hsp_hseq>VSSLFKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRS-LLRPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIME</Hsp_hseq>
      <Hsp_midline>VS  +   E IGRG F VV +  +  TG   A K ++         + QRE++ LA +     +     ++     L I+ E C+G  L   L++   I E  +   +R++L  +  +H+  V+H DIK           VKLCD G A ++      + +  GTP ++APE++++</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>7.08436e-11</Hsp_evalue>
      <Hsp_query-from>5731</Hsp_query-from>
      <Hsp_query-to>6288</Hsp_query-to>
      <Hsp_hit-from>34</Hsp_hit-from>
      <Hsp_hit-to>220</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>191</Hsp_align-len>
      <Hsp_qseq>FGVIRECKENATGRVFTAKIVPLEAASRAL--ALHEYEVLKALRQ-EHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXX-XHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMV-KGDAVGAPADVWGLAVLTFVLLSGESPF</Hsp_qseq>
      <Hsp_hseq>FGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSL--RSLLRPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTM--AGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPY</Hsp_hseq>
      <Hsp_midline>FGV+ +     TGRV+  K++ L++ S  +     E + L +L+Q  +I   + +Y+    L +I E C G  L  + L  P   ++  +G + + LL     +H+ +++H DIK+ N+++++   +KL DFG A     +   R  +   GT    APE++ +G       D+W L + T+ + +G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>2.74492e-11</Hsp_evalue>
      <Hsp_query-from>5830</Hsp_query-from>
      <Hsp_query-to>6336</Hsp_query-to>
      <Hsp_hit-from>202</Hsp_hit-from>
      <Hsp_hit-to>378</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>177</Hsp_align-len>
      <Hsp_qseq>EYEVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRT--------GTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPFLGANDEETEKNIRQCR</Hsp_qseq>
      <Hsp_hseq>ERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNK</Hsp_hseq>
      <Hsp_midline>E  +L  +   +I+ L  ++     L L+ +  PG ELFY L E     E  V  Y +++  AL +LH + +V+ D+K +N +++    L L DFG ++  A   A     P          GT E+ APE++ G A     D + L  L + +L G+ P+ G+N +     I+Q +</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>1.43265e-09</Hsp_evalue>
      <Hsp_query-from>1768</Hsp_query-from>
      <Hsp_query-to>2229</Hsp_query-to>
      <Hsp_hit-from>198</Hsp_hit-from>
      <Hsp_hit-to>378</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>183</Hsp_align-len>
      <Hsp_qseq>RSEAQRELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLG--------SAQELMPPGQPQ--YSATGTPEFVAPEIVLQQPVSTATDI---------CLSGTSPFLGENDRGTLMRVREGR</Hsp_qseq>
      <Hsp_hseq>RTFAERS--ILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNK</Hsp_hseq>
      <Hsp_midline>R+ A+R   IL+ + HP +  L  +F    +L +L +   G EL   L +   + E  V  Y  +I   + +LH  GV++ D+K           + L D G        SA +   P      YS  GTPE+ APEI+L +  S   D           L G  P+ G N +  + ++++ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>3.314e-11</Hsp_evalue>
      <Hsp_query-from>6031</Hsp_query-from>
      <Hsp_query-to>6327</Hsp_query-to>
      <Hsp_hit-from>1222</Hsp_hit-from>
      <Hsp_hit-to>1316</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>100</Hsp_align-len>
      <Hsp_qseq>HERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAV-GAPADVWGLAVLTFVLLSGESPFLGANDEETEKNIR</Hsp_qseq>
      <Hsp_hseq>HDQGIVHRDIKDENVIVDSKGFVKIIDFGSA-AYVKSG---PFDVFVGTIDYAAPEVLGGNPYEGQPQDIWAIGILLYTVVFKENPFYNI-DEILEGDLK</Hsp_hseq>
      <Hsp_midline>H++ IVH DIK +N+IV     +K++DFGSA ++  SG   P     GT++++APE++ G+   G P D+W + +L + ++  E+PF    DE  E +++</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>2.46304e-06</Hsp_evalue>
      <Hsp_query-from>1633</Hsp_query-from>
      <Hsp_query-to>2136</Hsp_query-to>
      <Hsp_hit-from>1090</Hsp_hit-from>
      <Hsp_hit-to>1279</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>194</Hsp_align-len>
      <Hsp_qseq>LRTVSDYYDVKEEIGRGTFSVVRRAVHRTTGLEVAAKFVSRA---------GGRRSEAQRELRILARVS---HPRLACLRDAFQTRRRLIILTELCSGE----ELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIKE----------VKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQP</Hsp_qseq>
      <Hsp_hseq>VKKFSDFVSL-QKMGEGAYGKVNLCIHKKNRYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKKPHENILRLLDFFEDDDYYYIETPV-HGETGCIDLFDLIEFKTNMTEFEAKLIFKQVVAGIKHLHDQGIVHRDIKDENVIVDSKGFVKIIDFGSAAYV--KSGPFDVFVGTIDYAAPEVLGGNP</Hsp_hseq>
      <Hsp_midline>++  SD+  + +++G G +  V   +H+     V  K + +            +      E++I+A ++   H  +  L D F+      I T +  GE    +L D +  K  ++E +     +Q++ G+ +LH  G++H DIK+          VK+ D GSA  +     P     GT ++ APE++   P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>4.39587e-11</Hsp_evalue>
      <Hsp_query-from>1663</Hsp_query-from>
      <Hsp_query-to>2217</Hsp_query-to>
      <Hsp_hit-from>14</Hsp_hit-from>
      <Hsp_hit-to>242</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>229</Hsp_align-len>
      <Hsp_qseq>KEEIGRGTFSVVRRAVHRTTGLEVAAKFVSRAGGRRSEAQ--------RELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPP-----------------GQPQYSATGTPEFVAPEIVLQQPVSTATDI----CL-----SGTSPFLGENDRGTLMRV</Hsp_qseq>
      <Hsp_hseq>KEELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPFRGENELKTFEKI</Hsp_hseq>
      <Hsp_midline>KEE+G G++S V +A+ + +  ++ A  V        EA+          + +LA+  H  +  L   F     L  + +   G ELL  L K    +++    +  Q+++ + ++H  G++H D+K           + + D G+A  + P                   Q   S  GT E+V+PE++L       +DI    C+      G  PF GEN+  T  ++</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>6.71543e-09</Hsp_evalue>
      <Hsp_query-from>5770</Hsp_query-from>
      <Hsp_query-to>6324</Hsp_query-to>
      <Hsp_hit-from>41</Hsp_hit-from>
      <Hsp_hit-to>242</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>203</Hsp_align-len>
      <Hsp_qseq>RVFTAKIVPLEAASRALALHEYEVLKALRQEHIMGLHEAYVT---PRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGA---------------PRPIVPRTGTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPFLGANDEETEKNI</Hsp_qseq>
      <Hsp_hseq>KVCSKKHIIKEAKVKYVTI-EKNTMNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPFRGENELKTFEKI</Hsp_hseq>
      <Hsp_midline>+V + K +  EA  + + + E   +  L Q+H  G+ + Y T      L  + +  PG EL   L +   + +     + +QL+ AL ++H   I+H D+K +N+++    +L + DFG+A +  PS +                +      GT E+ +PE++  +  G  +D+W L  + +  + G+ PF G N+ +T + I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>4.55707e-11</Hsp_evalue>
      <Hsp_query-from>1669</Hsp_query-from>
      <Hsp_query-to>2307</Hsp_query-to>
      <Hsp_hit-from>625</Hsp_hit-from>
      <Hsp_hit-to>856</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>234</Hsp_align-len>
      <Hsp_qseq>EIGRGTFSVVRRAVHRTTGLEVAAKFVSRAGGRRSE-AQRELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQPVSTATDI---------CLSGTSPFLGEND-RGTLMRVREGRFSLERCFSALSAEAGSFIARLLAVDP</Hsp_qseq>
      <Hsp_hseq>KIGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKELIINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTD-VVTHCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPPYLNETPLRALYLIATNGTPKLKEP-ENLSSSLKKFLDWCLCVEP</Hsp_hseq>
      <Hsp_midline>+IG+G    V  A    T + VA K ++     + E    E+ ++    HP +    D++  +  L ++ E   G  L D +V    ++E Q+    R+ L G+ +LH  GVLH DIK          ++KL D G   ++      + +  GTP ++APE+V ++      DI          + G  P+L E   R   +    G   L+     LS+    F+   L V+P</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>4.90545e-09</Hsp_evalue>
      <Hsp_query-from>5812</Hsp_query-from>
      <Hsp_query-to>6294</Hsp_query-to>
      <Hsp_hit-from>659</Hsp_hit-from>
      <Hsp_hit-to>816</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>161</Hsp_align-len>
      <Hsp_qseq>RALALHEYEVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPFLG</Hsp_qseq>
      <Hsp_hseq>KELIINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSL-TDVVTHCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTM--VGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPPYLN</Hsp_hseq>
      <Hsp_midline>+ L ++E  V+K  +  +I+   ++YV    L +I E   G  L   ++     TE  +     + L  L +LH + ++H DIKSDN+++S    +KL DFG           R  +   GT    APE+V     G   D+W L ++   ++ GE P+L </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>6.29175e-11</Hsp_evalue>
      <Hsp_query-from>1648</Hsp_query-from>
      <Hsp_query-to>2409</Hsp_query-to>
      <Hsp_hit-from>345</Hsp_hit-from>
      <Hsp_hit-to>612</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>120</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>281</Hsp_align-len>
      <Hsp_qseq>DYYDVKEEIGRGTFSVVRRAVHRTTGLEVAAK------FVSRAGGRRSEAQRELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQPVSTATDI---------CLSGTSPFLGENDRGTLMRVREGRFSLERCFSALSAEAGSFIARLLAVDPXXXXXXXXXXXXXXVGTDRIKF--FLSRRKWQRSLV</Hsp_qseq>
      <Hsp_hseq>DDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAER--TVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGF---DRDAKDLLIGLLSRDPTRRLGYN--------GADEIRNHPFFSQLSWKRLLM</Hsp_hseq>
      <Hsp_midline>D +D+ + IG+G+F  V +   + T    A K       VS++    + A+R   +LARV  P +  L+ +FQ+  +L  +    +G EL   L K+      +   Y  ++L  +  LH+  V++ D+K           + LCD G  +  M       +  GTPE++APE++L    + A D           L+G  P+  E+      ++ +        F     +A   +  LL+ DP + +  +        G D I+   F S+  W+R L+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>1.35572e-07</Hsp_evalue>
      <Hsp_query-from>5731</Hsp_query-from>
      <Hsp_query-to>6330</Hsp_query-to>
      <Hsp_hit-from>358</Hsp_hit-from>
      <Hsp_hit-to>559</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>206</Hsp_align-len>
      <Hsp_qseq>FGVIRECKENATGRVFTAK------IVPLEAASRALALHEYEVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPFLGANDEETEKNIRQ</Hsp_qseq>
      <Hsp_hseq>FGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLA--ERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTF--CGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQ</Hsp_hseq>
      <Hsp_midline>FG + + ++  T +V+  K      IV     +  LA  E  VL  +    I+ L  ++ +P  L  +     G ELFY L +  R+       Y ++LL AL  LH+  +V+ D+K +N+++     + L DFG  +               GT E+ APE++ G       D W L VL + +L+G  P+   +  +  K I Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>7.56853e-11</Hsp_evalue>
      <Hsp_query-from>1654</Hsp_query-from>
      <Hsp_query-to>2196</Hsp_query-to>
      <Hsp_hit-from>7</Hsp_hit-from>
      <Hsp_hit-to>210</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>206</Hsp_align-len>
      <Hsp_qseq>YDVKEEIGRGTFSVVRRAVHRTTGLEVAAKFVSRA---GGRRSEAQRELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAI--SELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVL-QQPVSTATDICLSGT--------SPFL-GEND</Hsp_qseq>
      <Hsp_hseq>YTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNVIELIDIFMAYDNLNLVLEFLPTD--LEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQND</Hsp_hseq>
      <Hsp_midline>Y  ++++G GT++VV      +TG ++A K +  +    G    A RE++ L  + HP +  L D F     L ++ E    +  L+ ++K  +I  +   +  ++   L GV++ H++ +LH D+K          ++K+ D G A+ +  P +   S   T  + APE++   +  ++A DI   G          P+L G+ND</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>1.9395e-06</Hsp_evalue>
      <Hsp_query-from>5731</Hsp_query-from>
      <Hsp_query-to>6303</Hsp_query-to>
      <Hsp_hit-from>18</Hsp_hit-from>
      <Hsp_hit-to>210</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>197</Hsp_align-len>
      <Hsp_qseq>FGVIRECKENATGRVFTAKIVPLEAASRAL---ALHEYEVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIV-PRTGTLEHSAPEMVKG-DAVGAPADVWGLAVLTFVLLSGESPFL-GAND</Hsp_qseq>
      <Hsp_hseq>YAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNVIELIDIFMAYDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIP---APHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVI-FAELMLRIPYLPGQND</Hsp_hseq>
      <Hsp_midline>+ V+    +++TGR    K +        L   A+ E + L+ ++  +++ L + ++    L L+ E  P         +S  +T  D+  ++   L  + + H   I+H D+K +NL+ S   ++K+ DFG AR+     AP  I+     T  + APE++ G     +  D+W + V+ F  L    P+L G ND</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>9.80147e-11</Hsp_evalue>
      <Hsp_query-from>5749</Hsp_query-from>
      <Hsp_query-to>6300</Hsp_query-to>
      <Hsp_hit-from>395</Hsp_hit-from>
      <Hsp_hit-to>586</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>194</Hsp_align-len>
      <Hsp_qseq>CKENATGRVFTAKIVPLEAASRALALHEYEVLKALRQEHIMGLHEAYV-TPRYLVLIAERCPGKELFYKLLESPR---------YTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPFLGAN</Hsp_qseq>
      <Hsp_hseq>CHRVVGERVAIKQIRLSEQPKKQLIMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATM--VGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPPYLNED</Hsp_hseq>
      <Hsp_midline>C      RV   +I   E   + L ++E  V+   RQE+I+   EAY+     L +I E   G  L   L    R           E+ +   + +    L +LH + I+H DIKSDN++++    +K+ DFG         + R  +   GT    APE+V         DVW L ++   ++ GE P+L  +</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>2.6573e-06</Hsp_evalue>
      <Hsp_query-from>1711</Hsp_query-from>
      <Hsp_query-to>2304</Hsp_query-to>
      <Hsp_hit-from>396</Hsp_hit-from>
      <Hsp_hit-to>623</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>228</Hsp_align-len>
      <Hsp_qseq>HRTTGLEVAAKFVSRAGG-RRSEAQRELRILARVSHPRLACLRDAFQTR-RRLIILTELCSG---EELLDRLVKKPA------ISELQVHPYIRQILEGVHYLHQSGVLHLDIKE----------VKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQPVSTATDIC---------LSGTSPFLGENDRGTLMRVREGRFSLERCFSALSAEAGSFIARLLAVD</Hsp_qseq>
      <Hsp_hseq>HRVVGERVAIKQIRLSEQPKKQLIMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANNGSPKLRHPESVSKQTKQFLDACLQVN</Hsp_hseq>
      <Hsp_midline>HR  G  VA K +  +   ++     EL ++       +    +A+      L ++ E   G    ++LD + +         ++E Q+   +++  +G+ +LH   ++H DIK           VK+ D G   EL      + +  GTP ++APEIV Q+      D+          + G  P+L E+    L  +        R   ++S +   F+   L V+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>1.20075e-10</Hsp_evalue>
      <Hsp_query-from>1552</Hsp_query-from>
      <Hsp_query-to>2304</Hsp_query-to>
      <Hsp_hit-from>59</Hsp_hit-from>
      <Hsp_hit-to>320</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>274</Hsp_align-len>
      <Hsp_qseq>HVSFVYDDAECSLVILSVSQADCGVYTLRTVSDYYDVKEEIGRGTFSVVRRAVHRTTGLEVAAKFVSRAGGRR----SEAQRELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQPVSTATDI---------CLSGTSPFLGENDRGTLMRVREGRFSLERCFSALSAEAGSFIARLLAVD</Hsp_qseq>
      <Hsp_hseq>HVT--YYNEEQYKQFIAQARVTSGKYSLQD----FQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAK-YVP--DVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFF---NEDVKDLLSRLITRD</Hsp_hseq>
      <Hsp_midline>HV+  Y + E     ++ ++   G Y+L+     + +   +G G+F  V     R  G   A K + +    R         E  +L+ V+HP +  +   FQ  +++ ++ +   G EL   L K           Y  ++   + YLH   +++ D+K           +K+ D G A+  +P     Y+  GTP+++APE+V  +P + + D           L+G +PF   N   T  ++          F   + +    ++RL+  D</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>1.91261e-10</Hsp_evalue>
      <Hsp_query-from>5731</Hsp_query-from>
      <Hsp_query-to>6324</Hsp_query-to>
      <Hsp_hit-from>98</Hsp_hit-from>
      <Hsp_hit-to>294</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>202</Hsp_align-len>
      <Hsp_qseq>FGVIRECKENATGRVFTAKIVPLEAASRALALH----EYEVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPFLGANDEETEKNI</Hsp_qseq>
      <Hsp_hseq>FGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKY-----VPDVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKI</Hsp_hseq>
      <Hsp_midline>FG +   +    GR +  K++  E   R   +     E  +L  +    I+ +   +   + + +I +   G ELF  L +S R+       Y +++ LAL YLH + I++ D+K +N+++  +  +K+ DFG A+       P       GT ++ APE+V         D W   +L + +L+G +PF  +N  +T + I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>1.26925e-10</Hsp_evalue>
      <Hsp_query-from>1654</Hsp_query-from>
      <Hsp_query-to>2307</Hsp_query-to>
      <Hsp_hit-from>121</Hsp_hit-from>
      <Hsp_hit-to>399</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>65</Hsp_gaps>
      <Hsp_align-len>281</Hsp_align-len>
      <Hsp_qseq>YDVKEEIGRGTFSVVRRAVHRTTGLE--VAAKFVSRAG---------------GRRSEAQRELRILARVSHPRLACLRD-AFQ-TRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------------------------------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQPVSTATDI----C-----LSGTSPFLGENDRGTLMRVREGRFS-LERCFSALSAEAGSFIARLLAVDP</Hsp_qseq>
      <Hsp_hseq>YKLLNKIGEGAFSRVFKAVGINTDDQAPVAIKAIIKKGISSDAILKGNDRIQGSSRKKVLNEVAIHKLVSKNNPHCTKFIAFQESANYYYLVTELVTGGEIFDRIVQLTCFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLR--NNTAKTPCGTIEYVASEVFTSKRYSMKVDMWSIGCVLFTLLCGYPPFYEKNEKTLLKKISRGDYEFLAPWWDNISSGAKNAVTHLLEVDP</Hsp_hseq>
      <Hsp_midline>Y +  +IG G FS V +AV   T  +  VA K + + G                 R +   E+ I   VS     C +  AFQ +     ++TEL +G E+ DR+V+    SE      I Q+   + ++H  G++H D+K                                   VKL D G A++L        +  GT E+VA E+   +  S   D+    C     L G  PF  +N++  L ++  G +  L   +  +S+ A + +  LL VDP</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>1.00676e-07</Hsp_evalue>
      <Hsp_query-from>5797</Hsp_query-from>
      <Hsp_query-to>6324</Hsp_query-to>
      <Hsp_hit-from>171</Hsp_hit-from>
      <Hsp_hit-to>368</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>202</Hsp_align-len>
      <Hsp_qseq>LEAASRALALHEYEVLKALRQE--HIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVS---------DSRK---------------LKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPFLGANDEETEKNI</Hsp_qseq>
      <Hsp_hseq>IQGSSRKKVLNEVAIHKLVSKNNPHCTKFIAFQESANYYYLVTELVTGGEIFDRIVQLTCFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLRNNTAKTPC----GTIEYVASEVFTSKRYSMKVDMWSIGCVLFTLLCGYPPFYEKNEKTLLKKI</Hsp_hseq>
      <Hsp_midline>++ +SR   L+E  + K + +   H         +  Y  L+ E   G E+F ++++   ++ED     ++Q+ +A+ ++H   IVH D+K +NL+           D +K               +KL+DFG A+    + A  P     GT+E+ A E+          D+W +  + F LL G  PF   N++   K I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>3.90588e-10</Hsp_evalue>
      <Hsp_query-from>1654</Hsp_query-from>
      <Hsp_query-to>2127</Hsp_query-to>
      <Hsp_hit-from>46</Hsp_hit-from>
      <Hsp_hit-to>223</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>178</Hsp_align-len>
      <Hsp_qseq>YDVKEEIGRGTFSVVRRAVHRTTG-----LEVAAKFVSRAGGRRSEAQ-----RELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVL</Hsp_qseq>
      <Hsp_hseq>YIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVV</Hsp_hseq>
      <Hsp_midline>Y +   +G G F  V+    + +       +VA K + R   ++   +     RE+  L  ++HP +  L +  Q  + + I+ E  SG E    + +K  + E        Q++ GV+Y+H  G++H D+K           + + D G   E     +   ++ G+P + APE+V+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>1.26409e-08</Hsp_evalue>
      <Hsp_query-from>5830</Hsp_query-from>
      <Hsp_query-to>6387</Hsp_query-to>
      <Hsp_hit-from>100</Hsp_hit-from>
      <Hsp_hit-to>278</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>188</Hsp_align-len>
      <Hsp_qseq>EYEVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAV--GAPADVWGLAVLTFVLLSGESPFLGANDEETEKNIRQCRPDITRCYVNVSQTALFF</Hsp_qseq>
      <Hsp_hseq>EINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDN--ELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLPW----DDDHEN---PTGDDIARLYKYITQTPLKF</Hsp_hseq>
      <Hsp_midline>E   LK L   +I+ L E     +Y+ ++ E   G E +  +    R  E       +QL+  + Y+H + +VH D+K +NL++     L + DFG    F        +    G+  ++APE+V          ADVW   V+ + +L+G  P+    D++ E        DI R Y  ++QT L F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>4.11991e-10</Hsp_evalue>
      <Hsp_query-from>5827</Hsp_query-from>
      <Hsp_query-to>6288</Hsp_query-to>
      <Hsp_hit-from>503</Hsp_hit-from>
      <Hsp_hit-to>657</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>155</Hsp_align-len>
      <Hsp_qseq>HEYEVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAP-SGAPRPIVPRTGTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPF</Hsp_qseq>
      <Hsp_hseq>HEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPF</Hsp_hseq>
      <Hsp_midline>HE  +LK L  E+I+  + A      L +  E  PG  +   L     + E  +  +  Q+L+ +AYLH+++I+H DIK  N+++     +K+ DFG ++  +P +          G++   +PE+VK  A  A AD+W    +   + +G+ PF</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>3.25068e-09</Hsp_evalue>
      <Hsp_query-from>1780</Hsp_query-from>
      <Hsp_query-to>2169</Hsp_query-to>
      <Hsp_hit-from>502</Hsp_hit-from>
      <Hsp_hit-to>644</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>143</Hsp_align-len>
      <Hsp_qseq>QRELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIKE----------VKLCDLGSAQELMPPGQPQY---SATGTPEFVAPEIVLQQPVSTATDICLSG</Hsp_qseq>
      <Hsp_hseq>QHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTG</Hsp_hseq>
      <Hsp_midline>Q E+ +L  + H  +     A Q    L I  E   G  +   L       E  +  + RQIL GV YLH+  ++H DIK           VK+ D G +++L P  + Q    S  G+  +++PE+V Q   +   DI  +G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>4.3614e-10</Hsp_evalue>
      <Hsp_query-from>1636</Hsp_query-from>
      <Hsp_query-to>2307</Hsp_query-to>
      <Hsp_hit-from>94</Hsp_hit-from>
      <Hsp_hit-to>362</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>55</Hsp_gaps>
      <Hsp_align-len>274</Hsp_align-len>
      <Hsp_qseq>RTVSDYYDVKEEIGRGTFSVVRRAVHRTTGLEVAAKFVSRAGGRRSEAQREL-------RILAR-----------------------VSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQPVS-TATDI---------CLSGTSPFLGENDRGTLMRVREGRFSLERCFSALSAEAGSFIARLLAVDP</Hsp_qseq>
      <Hsp_hseq>RSLGDW-EFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESEILERQKRLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLS-NIFDYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYP---SHLSIEVISLLTRMIVVDP</Hsp_hseq>
      <Hsp_midline>R++ D+ +  E +G G+   V+   HR T      K V+RA       Q  L        IL R                       + HP +  L +         +L E  SG +LLD +++  ++ E     + R I   + YLH + ++H D+K          E+K+ D G +  +    +  ++  G+  F APE++  QP +    DI          + G  PF  EN      ++++G+       S LS E  S + R++ VDP</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>5.29587e-10</Hsp_evalue>
      <Hsp_query-from>5800</Hsp_query-from>
      <Hsp_query-to>6342</Hsp_query-to>
      <Hsp_hit-from>163</Hsp_hit-from>
      <Hsp_hit-to>341</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>182</Hsp_align-len>
      <Hsp_qseq>EAASRALALHEYEVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAVGAP-ADVWGLAVLTFVLLSGESPFLGANDEETEKNIRQCRPD</Hsp_qseq>
      <Hsp_hseq>EIARDKRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIF---DYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVD</Hsp_hseq>
      <Hsp_midline>E A     + E  + + L   HI  L E      +  ++ E   G +L   +++     E     +   +  AL YLH  +IVH D+K +N+++S S ++K++DFG +  F      + +    G+L  +APE++K      P  D+W   ++ +VL+ G+ PF   N     + I++ + D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>6.09245e-10</Hsp_evalue>
      <Hsp_query-from>1639</Hsp_query-from>
      <Hsp_query-to>2169</Hsp_query-to>
      <Hsp_hit-from>8</Hsp_hit-from>
      <Hsp_hit-to>210</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>207</Hsp_align-len>
      <Hsp_qseq>TVSDYYDVKEEIGRGTFSVVRRAVHRTTGLEVAAK----FVSRAGGRRSEAQRELRILARVSHPRLACLR-----DAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQEL----MPPGQPQYSATGTPEFV------APEIVLQQ-PVSTATDICLSG</Hsp_qseq>
      <Hsp_hseq>NISSDFQLKSLLGEGAYGVVCSATHKPTGEIVAIKKIEPFDKPLFALRT--LREIKILKHFKHENIITIFNIQRPDSFENFNEVYIIQELMQTD--LHRVISTQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCG</Hsp_hseq>
      <Hsp_midline> +S  + +K  +G G + VV  A H+ TG  VA K    F       R+   RE++IL    H  +  +      D+F+    + I+ EL   +  L R++    +S+  +  +I Q L  V  LH S V+H D+K          ++K+CD G A+ +        +P    +G  E+V      APE++L     S A D+   G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>7.91522e-10</Hsp_evalue>
      <Hsp_query-from>1639</Hsp_query-from>
      <Hsp_query-to>2307</Hsp_query-to>
      <Hsp_hit-from>1029</Hsp_hit-from>
      <Hsp_hit-to>1295</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>267</Hsp_align-len>
      <Hsp_qseq>TVSDYYDVKEEIGRGTFSVVRRAVHRTTGLEVAAKFVSRAGGRRSEA-----QRELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIKE----------VKLCDLGSA----------------QELMPPGQPQYSATGTPEFVAPEIVLQQPVS---TATDI----CL-----SGTSPFLG-ENDRGTLMRVREGRFSLERCFSALSAEAGSFIARLLAVDP</Hsp_qseq>
      <Hsp_hseq>NVSMRWQKRSFIGGGTFGQVYSAINLENGEILAVKEIKIHDTTTMKKIFPLIKEEMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEYCEGGSLASLLDHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPWSNLDNEWAIMYHVAAGRIPQLPNRDEMTAAGRAFLERCLVQDP</Hsp_hseq>
      <Hsp_midline> VS  +  +  IG GTF  V  A++   G  +A K +        +      + E+ +L  ++HP +         R ++ I  E C G  L   L       E+    Y  ++LEG+ YLHQSGV+H DIK           +K  D G+A                Q+     +      GTP ++APE +    V     A D+    C+     +G  P+   +N+   +  V  GR         ++A   +F+ R L  DP</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>3.70986e-06</Hsp_evalue>
      <Hsp_query-from>5830</Hsp_query-from>
      <Hsp_query-to>6306</Hsp_query-to>
      <Hsp_hit-from>1083</Hsp_hit-from>
      <Hsp_hit-to>1258</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>178</Hsp_align-len>
      <Hsp_qseq>EYEVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXX--XXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGA--------------PRPIVPRTGTLEHSAPEMVKGDAVGAPA---DVWGLAVLTFVLLSGESPFLGANDE</Hsp_qseq>
      <Hsp_hseq>EMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEYCEGGSL-ASLLDHGR-IEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPWSNLDNE</Hsp_hseq>
      <Hsp_midline>E  VL+ L   +I+  +   V    + +  E C G  L   LL+  R  ED++V  +    L    AYLH+  +VH DIK +N+++  +  +K VDFG+AR+   S                 + +    GT  + APE + G AV       DVW L  +   + +G  P+   ++E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>8.75217e-10</Hsp_evalue>
      <Hsp_query-from>5731</Hsp_query-from>
      <Hsp_query-to>6360</Hsp_query-to>
      <Hsp_hit-from>13</Hsp_hit-from>
      <Hsp_hit-to>252</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>246</Hsp_align-len>
      <Hsp_qseq>FGVIRECKENATGRVFTAKIVPLEAASRALALHEYEVLKALR----QEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLE---------SPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKG-----------DAVGAP------ADVWGLAVLTFVLLSGESPFLGANDEETE--KNIRQCRPD----ITRCYV</Hsp_qseq>
      <Hsp_hseq>FSTVYKAWSTTHNRYVALKITPKYKTSEANMKNEYDVMKILSSCNPHPNICSMLDFYTDDSYYIMVLEYCECGDL-YDFLDIAKSQGSPSSPSLIQIDMQKIIKQLCSAISFAHSLGIAHRDIKPENILLTINGDIKLADWGHAIQ-----SPKSNDFQIGTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFGDCLFRVSKSKKVQHLKNFDEFEKDPFAFIYRKYV</Hsp_hseq>
      <Hsp_midline>F  + +       R    KI P    S A   +EY+V+K L       +I  + + Y    Y +++ E C   +L Y  L+         SP   + D+   + QL  A+++ H   I H DIK +N++++ +  +KL D+G A       +P+    + GT  + APE   G           D   AP      AD W L    F L+ G+  F  +  ++ +  KN  +   D    I R YV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>9.00774e-10</Hsp_evalue>
      <Hsp_query-from>1630</Hsp_query-from>
      <Hsp_query-to>2070</Hsp_query-to>
      <Hsp_hit-from>1258</Hsp_hit-from>
      <Hsp_hit-to>1419</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>162</Hsp_align-len>
      <Hsp_qseq>TLRTVSDYYDVKEEIGRGTFSVVRRAVHRTTGLEVAAKFVSRAGGRRSEA-----QRELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIKE----------VKLCDLGSAQELMPPG</Hsp_qseq>
      <Hsp_hseq>SISNVSMRWQKRNFIGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAALLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNG</Hsp_hseq>
      <Hsp_midline>++  VS  +  +  IG GTF  V  AV    G  +A K ++    +  +      + E+ +L  ++HP +         R ++ I  E C G  L   L       E+    Y  Q+LEG+ YLH+SG++H D+K           +K  D G+A+++   G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>1.05868e-09</Hsp_evalue>
      <Hsp_query-from>1666</Hsp_query-from>
      <Hsp_query-to>2169</Hsp_query-to>
      <Hsp_hit-from>43</Hsp_hit-from>
      <Hsp_hit-to>227</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>189</Hsp_align-len>
      <Hsp_qseq>EEIGRGTFSVVRRAVHRTTGLEVAAKFVSRAGGRRSEAQRELRILARVSHPRLACLRDAFQTRR-------RLIILTELCSGEELLDRLV-KKPAISELQVHPYIRQILEGVHYLHQ-SGVLHLDIK-----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVL-QQPVSTATDICLSG</Hsp_qseq>
      <Hsp_hseq>EVVGHGSFGVVFATVIQETNEKVAIKKVLQDKRFKN---RELEIMKMLSHINIIDLKYFFYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQL-KPTEPNVSYICSRYYRAPELIFGATNYTNQIDIWSSG</Hsp_hseq>
      <Hsp_midline>E +G G+F VV   V + T  +VA K V +    ++   REL I+  +SH  +  L+  F  R         LI+     S  + L   V ++  +S L++  Y+ Q+ + ++YLH  + V H DIK            +KLCD GSA++L  P +P  S   +  + APE++      +   DI  SG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>1.06233e-09</Hsp_evalue>
      <Hsp_query-from>5863</Hsp_query-from>
      <Hsp_query-to>6339</Hsp_query-to>
      <Hsp_hit-from>93</Hsp_hit-from>
      <Hsp_hit-to>249</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>HIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAV-GAPADVWGLAVLTFVLLSGESPFLGANDEETEKNIRQCRP</Hsp_qseq>
      <Hsp_hseq>YITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTRECMTKTTLETVC---GTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEP</Hsp_hseq>
      <Hsp_midline>+I  L+E  VT   + +  E CPGKEL+  LL   R +  +     +Q+  A+ Y H  H VH D+K +N+++  +   KL DFG  R          +    GT  + APE+++     G   D+W L V+ + L++G  PF   ++ +T+  I    P</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>4.17628e-07</Hsp_evalue>
      <Hsp_query-from>1654</Hsp_query-from>
      <Hsp_query-to>2307</Hsp_query-to>
      <Hsp_hit-from>41</Hsp_hit-from>
      <Hsp_hit-to>272</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>240</Hsp_align-len>
      <Hsp_qseq>YDVKEEIGRGTFSVVRRAVHRTTGLEVAAKFVSRAGGRRSEAQRELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQPVST-ATDI---------CLSGTSPFLGENDRGTLMRV--REGRFSLERCFSALSAEAGSFIARLLAVDP</Hsp_qseq>
      <Hsp_hseq>YKILKQIGEGSFGKVYLALHRPTHRKVCLKTSDKND---PNIVREVFYHRQFDFPYITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTRECMTKTTLE-TVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDAK----VIPDDARDLISRLLAKNP</Hsp_hseq>
      <Hsp_midline>Y + ++IG G+F  V  A+HR T  +V  K   +         RE+    +   P +  L +   T  ++ +  E C G+EL D L+    IS L+      QI   V+Y H    +H D+K            KL D G  +E M     + +  GT  ++APE++ ++       DI          ++G  PF  +++  T  ++   E ++  +     +  +A   I+RLLA +P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>1.61511e-09</Hsp_evalue>
      <Hsp_query-from>6043</Hsp_query-from>
      <Hsp_query-to>6303</Hsp_query-to>
      <Hsp_hit-from>327</Hsp_hit-from>
      <Hsp_hit-to>409</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>87</Hsp_align-len>
      <Hsp_qseq>IVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPFLGAND</Hsp_qseq>
      <Hsp_hseq>IIHRDIKPSNVLINSKGQIKLCDFGVSKKLINSIADTFV----GTSTYMSPERIQGNVYSIKGDVWSLGLMIIELVTGEFPLGGHND</Hsp_hseq>
      <Hsp_midline>I+H DIK  N++++   ++KL DFG ++    S A   +    GT  + +PE ++G+      DVW L ++   L++GE P  G ND</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>1.99198e-09</Hsp_evalue>
      <Hsp_query-from>5845</Hsp_query-from>
      <Hsp_query-to>6288</Hsp_query-to>
      <Hsp_hit-from>71</Hsp_hit-from>
      <Hsp_hit-to>222</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>154</Hsp_align-len>
      <Hsp_qseq>KALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXH---ERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSF-APSGAPRPIVPRTGTLEHSAPEMVKGDA--VGAPADVWGLAVLTFVLLSGESPF</Hsp_qseq>
      <Hsp_hseq>KCSKHPNVLRLIDCNVSKEYMWIILEMADGGDLFDKI--EPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQTPW</Hsp_hseq>
      <Hsp_midline>K  +  +++ L +  V+  Y+ +I E   G +LF K+   P    D  V       L  A  +   E  + H DIK +N+++  +  LKL DFG A  F    G  R  + + G+  + APE++  +        D+W + +L FVLL+G++P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>3.22466e-08</Hsp_evalue>
      <Hsp_query-from>5734</Hsp_query-from>
      <Hsp_query-to>6285</Hsp_query-to>
      <Hsp_hit-from>233</Hsp_hit-from>
      <Hsp_hit-to>421</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>193</Hsp_align-len>
      <Hsp_qseq>GVIRECKENATGRVFTAKIVPL---EAASRALALHEYEVLKALRQEHIMGLHEAYVTPRY--LVLIAERCPGKEL---FYKLLESPRYTEDDVVGXXXXXXXX-XXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESP</Hsp_qseq>
      <Hsp_hseq>GSVSKCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQFNRSFQSEYIVRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVSGEAVNSLA----TTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANGKFP</Hsp_hseq>
      <Hsp_midline>G + +CK     ++F  K++     +   +     E +  ++ + E+I+  +  +       + +  E   G+ L   +  LLE      + V+G +++ +L  L+YLHE+ ++H DIK  N++++++ ++KL DFG +     S A       TGT  + APE ++G      +DVW L +    + +G+ P</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>2.28471e-06</Hsp_evalue>
      <Hsp_query-from>1927</Hsp_query-from>
      <Hsp_query-to>2232</Hsp_query-to>
      <Hsp_hit-from>321</Hsp_hit-from>
      <Hsp_hit-to>420</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>112</Hsp_align-len>
      <Hsp_qseq>ISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQPVSTATDICLSGTSPFLGENDRGTLMRVREGRF</Hsp_qseq>
      <Hsp_hseq>ISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVSGEAVNSLATTF--TGTSFYMAPERIQGQPYSVTSDVWSLGL----------TILEVANGKF</Hsp_hseq>
      <Hsp_midline>ISE  +      +L G+ YLH+  V+H DIK          +VKLCD G + E +      +  TGT  ++APE +  QP S  +D+   G           T++ V  G+F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>3.32664e-08</Hsp_evalue>
      <Hsp_query-from>5734</Hsp_query-from>
      <Hsp_query-to>6288</Hsp_query-to>
      <Hsp_hit-from>226</Hsp_hit-from>
      <Hsp_hit-to>415</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>194</Hsp_align-len>
      <Hsp_qseq>GVIRECKENATGRVFTAKIVPL---EAASRALALHEYEVLKALRQEHIMGLHEAYVTPRY--LVLIAERCPGKEL---FYKLLESPRYTEDDVVGXXXXXXX-XXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPF</Hsp_qseq>
      <Hsp_hseq>GSVAKCRLKNGKKVFALKTINTMNTDPEYQKQIFRELQFNKSFKSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFGVSGEAVNSLA----MTFTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRFPF</Hsp_hseq>
      <Hsp_midline>G + +C+     +VF  K +     +   +     E +  K+ + ++I+  +  +   +   + +  E   GK L   +  LL+      + V+G +++ +L  L+YLHER ++H DIK  N+++++  ++KL DFG +     S A    +  TGT  + APE ++G       DVW L +    +  G  PF</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>3.45997e-07</Hsp_evalue>
      <Hsp_query-from>1861</Hsp_query-from>
      <Hsp_query-to>2241</Hsp_query-to>
      <Hsp_hit-from>288</Hsp_hit-from>
      <Hsp_hit-to>416</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>141</Hsp_align-len>
      <Hsp_qseq>LIILTELCSGEEL---LDRLVKKPA-ISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQPVSTATDICLSGTSPFLGENDRGTLMRVREGRFSLE</Hsp_qseq>
      <Hsp_hseq>IYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFGVSGEAV--NSLAMTFTGTSFYMAPERIQGQPYSVTCDVWSLGL----------TLLEVAGGRFPFE</Hsp_hseq>
      <Hsp_midline>+ I  E   G+ L      L+K+   ISE  +      +L G+ YLH+  V+H DIK          E+KLCD G + E +       + TGT  ++APE +  QP S   D+   G           TL+ V  GRF  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>4.22168e-08</Hsp_evalue>
      <Hsp_query-from>5731</Hsp_query-from>
      <Hsp_query-to>6132</Hsp_query-to>
      <Hsp_hit-from>363</Hsp_hit-from>
      <Hsp_hit-to>500</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>138</Hsp_align-len>
      <Hsp_qseq>FGVIRECKENATGRVFTAK-IVPLEAASRALALH---EYEVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSF</Hsp_qseq>
      <Hsp_hseq>FGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGF</Hsp_hseq>
      <Hsp_midline>FG +R  ++  TG+++  K ++  E   +    H   E +VL       ++ L+ ++   +YL LI E  PG +L   L+    +TED    Y+++ +LA+  +H+   +H DIK DN+++     +KL DFG +  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>1.11215e-07</Hsp_evalue>
      <Hsp_query-from>1669</Hsp_query-from>
      <Hsp_query-to>2058</Hsp_query-to>
      <Hsp_hit-from>188</Hsp_hit-from>
      <Hsp_hit-to>331</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>144</Hsp_align-len>
      <Hsp_qseq>EIGRGTFSVVRRAVHRTTGLEVAAKFVSRAGGRRS---EAQRELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPA-ISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQEL</Hsp_qseq>
      <Hsp_hseq>QVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNVSTIKEIMVESQKTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKM</Hsp_hseq>
      <Hsp_midline>++G GT+  V +A +  T   VA K +   G R      + RE+++L    HP ++ +++     ++ + +    +  +L   L+ K   IS  Q     +Q+L G+ YLH + +LH D+K           +K+ D G A+++</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>3.53272e-07</Hsp_evalue>
      <Hsp_query-from>6031</Hsp_query-from>
      <Hsp_query-to>6309</Hsp_query-to>
      <Hsp_hit-from>298</Hsp_hit-from>
      <Hsp_hit-to>388</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>94</Hsp_align-len>
      <Hsp_qseq>HERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDA-VGAPADVWGLAVLTFVLLSGESPFLGANDEE</Hsp_qseq>
      <Hsp_hseq>HDNKILHRDVKGSNILIDNQGNLKITDFGLARKMNSRAD---YTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELE</Hsp_hseq>
      <Hsp_midline>H+  I+H D+K  N+++ +   LK+ DFG AR             R  TL +  PE++ G    G   D+WG   L   L +  + F G+N+ E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>1.15889e-07</Hsp_evalue>
      <Hsp_query-from>5731</Hsp_query-from>
      <Hsp_query-to>6303</Hsp_query-to>
      <Hsp_hit-from>380</Hsp_hit-from>
      <Hsp_hit-to>575</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>203</Hsp_align-len>
      <Hsp_qseq>FGVIRECKENATGRVFTAKIVPLEAASRALALHEYEVLKALRQE-------HIMGLHEAYVTPRYLVLIAERCPGKELFYKLLESPRY---TEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIV--SDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPFLGAND</Hsp_qseq>
      <Hsp_hseq>FGQVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKNHLCLVFELLSNN--LYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPELKIIDFGSSCEEA-----RTVYTYIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAELFLGIPIFPGASE</Hsp_hseq>
      <Hsp_midline>FG + +C+   T  +   K+V         ++ E ++L+ L Q+       H + +++++V   +L L+ E        Y+LL+  ++   +   +  + +Q+L +L  L E  ++H D+K +N+++   D  +LK++DFGS+   A     R +     +  + APE++ G       D+W L  +   L  G   F GA++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>1.83573e-07</Hsp_evalue>
      <Hsp_query-from>5830</Hsp_query-from>
      <Hsp_query-to>6366</Hsp_query-to>
      <Hsp_hit-from>73</Hsp_hit-from>
      <Hsp_hit-to>294</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>225</Hsp_align-len>
      <Hsp_qseq>EYEVLKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFY------KLLES-----------PRYTEDD-------VVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVS-------DSRK--------------LKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAVGAPADVWGLAVLTFVLLSGESPFLGANDEETEKNIRQCRPDITR-CYVNV</Hsp_qseq>
      <Hsp_hseq>EIAILKKIKHPHIVGLIDCERTSTDFYLIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFAR-FLPNTSLAETL--CGSPLYMAPEILNYQKYNAKADLWSVGTVVFEMCCGTPPFRASNHLELFKKIKRANDVITFPSYCNI</Hsp_hseq>
      <Hsp_midline>E  +LK ++  HI+GL +   T     LI E C   +L +      +L+E+           P  +E+        V+ YL QL  AL +L  +++VH DIK  NL++S       DS+               LK+ DFG AR F P+ +    +   G+  + APE++      A AD+W +  + F +  G  PF  +N  E  K I++    IT   Y N+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>2.29908e-07</Hsp_evalue>
      <Hsp_query-from>1660</Hsp_query-from>
      <Hsp_query-to>2190</Hsp_query-to>
      <Hsp_hit-from>35</Hsp_hit-from>
      <Hsp_hit-to>232</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>200</Hsp_align-len>
      <Hsp_qseq>VKE--EIGRGTFSVVRRAVHRTTGLEVAAKF-VSRAGGRRSEAQRELRILARVSHPRLACLRDAF-----QTRRRLIILTELCSGEEL---LDRLV-KKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIKE-----------VKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVLQQPVSTATDICLSGTSPFLGE</Hsp_qseq>
      <Hsp_hseq>VKEYRKIGRGAFGTVVQAYLTQDKKNWLGPFAIKKVPAHTEYKSRELQILRIADHPNIVKLQYFFTHLSPQDNKVYQHLAMECLPETLQIEINRYVTNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKL-EHNQPSISYICSRFYRAPELIIGCTQYT-TQIDIWGLGCVMGE</Hsp_hseq>
      <Hsp_midline>VKE  +IGRG F  V +A            F + +         REL+IL    HP +  L+  F     Q  +    L   C  E L   ++R V  K  +    +  Y  QI  G+ YLH  GV H DIK            +K+CD GSA++L    QP  S   +  + APE+++     T T I + G    +GE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>2.91591e-07</Hsp_evalue>
      <Hsp_query-from>1654</Hsp_query-from>
      <Hsp_query-to>2292</Hsp_query-to>
      <Hsp_hit-from>13</Hsp_hit-from>
      <Hsp_hit-to>265</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>254</Hsp_align-len>
      <Hsp_qseq>YDVKEEIGRGTFSVVRRAVHRTTGLEVAAKFVSRAGGRR--SEAQRELRILARV-SHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKK---------PAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQELMPPGQPQYSATG-------TPEFVAPEIVLQ-QPVSTATDI----CL-----SGTSPFLGENDRGTLMRVRE--GRFSLERCFSALSAEAGSFIARL</Hsp_qseq>
      <Hsp_hseq>YKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRP-VSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIANL</Hsp_hseq>
      <Hsp_midline>Y + + IG G +  V  A+H+ +G++VA K +     +   +   RE+++L     H  +  + D  +    +  L  +   EEL++  ++K           +S+  V  +  QIL  +  +H + V+H DIK          ++K+CD G A+ L      + +  G       T  + APEI+L  Q  +TA DI    C+     SG   F G +    L  + E  G  S E      S  A  +IA L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>3.18209e-07</Hsp_evalue>
      <Hsp_query-from>1645</Hsp_query-from>
      <Hsp_query-to>2124</Hsp_query-to>
      <Hsp_hit-from>15</Hsp_hit-from>
      <Hsp_hit-to>187</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>175</Hsp_align-len>
      <Hsp_qseq>SDYYDVKEEIGRGTFSVVRRAVHRTTGLEVAAKFVSRAGGRRSEA--QRELRILARVSHPRLACLRDAFQTRRRLIILTELCSGEELLDRLVKKPAIS---ELQVHPYIRQILEGVHYLHQSGVLHLDIKE----------VKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIV</Hsp_qseq>
      <Hsp_hseq>SKLYSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSD-LLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLK-RDTFVGTPYWMAPEVV</Hsp_hseq>
      <Hsp_midline>S  Y ++  IGRG F  V +AV R T   VA K V+            +E+  LA +  P +            + I+ E C G    D L+K+  ++   E +V   I ++  G+ YLH+   +H DIK           VKL D G +  +    + + +  GTP ++APE+V</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>1.91195e-06</Hsp_evalue>
      <Hsp_query-from>5731</Hsp_query-from>
      <Hsp_query-to>6339</Hsp_query-to>
      <Hsp_hit-from>29</Hsp_hit-from>
      <Hsp_hit-to>234</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>212</Hsp_align-len>
      <Hsp_qseq>FGVIRECKENATGRVFTAKIVPLEAASRALALHEYEV--LKALRQEHIMGLHEAYVTPRYLVLIAERCPGKELFYKLLES--PRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPR---TGTLEHSAPEMV--KGDAVGAPADVWGLAVLTFVLLSGESPFLGANDEETEKNIRQCRP</Hsp_qseq>
      <Hsp_hseq>FGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGV------SGHIRSTLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPPLSKYDPMKVMTNLPKRKP</Hsp_hseq>
      <Hsp_midline>FG + +  +  T  +   K+V LE +   + L   E+  L  L+   I       +    + ++ E C G      L  S      E+ V   + ++ L L YLHE+  +H DIK+ N+++++   +KL DFG       SG  R  + R    GT    APE+V  + D     AD+W L + T+ LL G  P    +  +   N+ + +P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>6.89943e-07</Hsp_evalue>
      <Hsp_query-from>5827</Hsp_query-from>
      <Hsp_query-to>6288</Hsp_query-to>
      <Hsp_hit-from>103</Hsp_hit-from>
      <Hsp_hit-to>276</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>183</Hsp_align-len>
      <Hsp_qseq>HEYEVLKALRQEHIMGLHEAYVTPR----YLVLI------AERCPGKELFYKLLESPRYTEDDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAPRPIVPRTGTLEHSAPEMVKGDAVGAPA-------------------DVWGLAVLTFVLLSGESPF</Hsp_qseq>
      <Hsp_hseq>QEIEVMKRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVAMSTATGST---------NIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPF</Hsp_hseq>
      <Hsp_midline> E EV+K    E+++ L+E    P     YLVL        + CP  ++  K +     T       +  ++  L YLH + I H DIK  NL++S +  +K+ DFG A S A              ++ S  +++K  A+G PA                   D+W L V  + LL G+ PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YKL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:347214:349136:-1 gene:YKL048C transcript:YKL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ELM1 description:Serine/threonine protein kinase; regulates the orientation checkpoint, the morphogenesis checkpoint and the metabolic switch from fermentative to oxidative metabolism by phosphorylating the activation loop of Kin4p, Hsl1p and Snf4p respectively; cooperates with Hsl7p in recruiting Hsl1p to the septin ring, a prerequisite for subsequent recruitment, phosphorylation, and degradation of Swe1p; forms part of the bud neck ring; regulates cytokinesis [Source:SGD;Acc:S000001531]</Hit_def>
  <Hit_accession>YKL048C</Hit_accession>
  <Hit_len>640</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>9.00462e-07</Hsp_evalue>
      <Hsp_query-from>6031</Hsp_query-from>
      <Hsp_query-to>6312</Hsp_query-to>
      <Hsp_hit-from>251</Hsp_hit-from>
      <Hsp_hit-to>362</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>113</Hsp_align-len>
      <Hsp_qseq>HERHIVHLDIKSDNLIVSDSRKL-KLVDFGSARSFAPSGAP-----------RPIVPRTGTLEHSAPEMV-----KGDAV--GAPADVWGLAVLTFVLLSGESPFLGANDEET</Hsp_qseq>
      <Hsp_hseq>HSQGCIHRDIKPSNILLDEEEKVAKLSDFGSC-IFTPQSLPFSDANFEDCFQRELNKIVGTPAFIAPELCHLGNSKRDFVTDGFKLDIWSLGVTLYCLLYNELPFFGENEFET</Hsp_hseq>
      <Hsp_midline>H +  +H DIK  N+++ +  K+ KL DFGS   F P   P           R +    GT    APE+      K D V  G   D+W L V  + LL  E PF G N+ ET</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>1.54105e-06</Hsp_evalue>
      <Hsp_query-from>1639</Hsp_query-from>
      <Hsp_query-to>2169</Hsp_query-to>
      <Hsp_hit-from>33</Hsp_hit-from>
      <Hsp_hit-to>237</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>214</Hsp_align-len>
      <Hsp_qseq>TVSDYYDVKEEIGRGTFSVV--RRAVHRTTGLEVAAKFVSRAGGRRSEAQRELRILARVS----HPRLACLRDAFQTRRRLIILTE-----LCSGEELLDRLVKKP-----AISELQVHPYIRQILEGVHYLHQSGVLHLDIKE----------VKLCDLGSAQEL----------MPPGQPQYSATGTPEFVAPEIVL-QQPVSTATDICLSG</Hsp_qseq>
      <Hsp_hseq>SIPGYYEIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGHKNIVNLID-------LEIVTSSPYDGLYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRW--YRAPELLLSNQPYSKSVDIWAVG</Hsp_hseq>
      <Hsp_midline>++  YY++ + +G+G +  V   +   R+    +A K +S    +    +R +R L  ++    H  +  L D       L I+T      L   +EL+D  + K       +SE  +  ++ QIL G+ Y+H + V+H D+K           +K+CD G A+ +          + P    Y AT    + APE++L  QP S + DI   G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>4.35526e-06</Hsp_evalue>
      <Hsp_query-from>5731</Hsp_query-from>
      <Hsp_query-to>6306</Hsp_query-to>
      <Hsp_hit-from>19</Hsp_hit-from>
      <Hsp_hit-to>217</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>211</Hsp_align-len>
      <Hsp_qseq>FGVIRECKENATG---RVFTAKIVPLEAASRAL---ALHEYEVLKALRQEHIMGLHE-AYVTPRYLVLIAERCPGKELFYKLLESPRYTE----------DDVVGXXXXXXXXXXXXHERHIVHLDIKSDNLIVSDSRKLKLVDFGSARSFAPSGAP-RPIVPRTGTLEHSAPE-MVKGDAVGAPADVWGLAVLTFVLLSGESPFLGANDE</Hsp_qseq>
      <Hsp_hseq>YGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFE--------FLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAF---GVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCI-FAEMCNRKPIFSGDSE</Hsp_hseq>
      <Hsp_midline>+GV+ +  +   G   RV   K + LE+    +   A+ E  +LK L+ ++I+ L++  +     L L+ E        +  L+  RY E          D V  ++ QL   +AY H   I+H D+K  NL+++    LKL DFG AR+F   G P R       TL + APE ++ G       D W +  + F  +    P    + E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YDL079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:312951:314748:-1 gene:YDL079C transcript:YDL079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRK1 description:Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication [Source:SGD;Acc:S000002237]</Hit_def>
  <Hit_accession>YDL079C</Hit_accession>
  <Hit_len>501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>5.75965e-06</Hsp_evalue>
      <Hsp_query-from>1639</Hsp_query-from>
      <Hsp_query-to>2127</Hsp_query-to>
      <Hsp_hit-from>159</Hsp_hit-from>
      <Hsp_hit-to>337</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>183</Hsp_align-len>
      <Hsp_qseq>TVSDYYDVKEEIGRGTFSVVRRAVHRTTGLEVAAKFVSRAGGRRSEAQRELRILARVSHPRLACLRDAFQTRR-------RLIILTELCSGEELLDRLVK-KPAISELQVHPYIRQILEGVHYLHQS-GVLHLDIK-----------EVKLCDLGSAQELMPPGQPQYSATGTPEFVAPEIVL</Hsp_qseq>
      <Hsp_hseq>TIDISYPTTEVVGHGSFGVVVTTVIIETNQKVAIKKVLQD---RRYKNRELETMKMLCHPNTVGLQYYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAK-CLKPDQPNVSYICSRYYRAPELMF</Hsp_hseq>
      <Hsp_midline>T+   Y   E +G G+F VV   V   T  +VA K V +    R    REL  +  + HP    L+  F  +         L++     S  + L   V  K  +  +++  Y  Q+ + ++YLH    + H DIK             K+CD GSA+  + P QP  S   +  + APE++ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>6.25611e-06</Hsp_evalue>
      <Hsp_query-from>1651</Hsp_query-from>
      <Hsp_query-to>2133</Hsp_query-to>
      <Hsp_hit-from>315</Hsp_hit-from>
      <Hsp_hit-to>503</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>189</Hsp_align-len>
      <Hsp_qseq>YYDVKEEIGRGTFSVVR----RAVHRTTGLEVAAKFVSRAGGRRSEAQ---------RELRILARVSHPRLACLRDAFQ-TRRRLIILTELCSGEELLDRLVKKPAISELQVHPYIRQILEGVHYLHQSGVLHLDIKE----------VKLCDLGSAQELMPPGQPQY----SATGTPEFVAPEIVLQQ</Hsp_qseq>
      <Hsp_hseq>YGRCQEVLGKGAFGVVRICQKKNVSSQDGNKSEKLYAVKEFKRRTSESAEKYSKRLTSEFCISSSLHHTNIVTTLDLFQDAKGEYCEVMEYCAGGDLFTLVVAAGKLEYMEADCFFKQLIRGVVYMHEMGVCHRDLKPENLLLTHDGVLKITDFGNSECFKMAWEKNIHLSGGVCGSSPYIAPEEYIKE</Hsp_hseq>
      <Hsp_midline>Y   +E +G+G F VVR    + V    G +    +  +   RR+             E  I + + H  +    D FQ  +     + E C+G +L   +V    +  ++   + +Q++ GV Y+H+ GV H D+K           +K+ D G+++      +          G+  ++APE  +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>7.87134e-06</Hsp_evalue>
      <Hsp_query-from>1639</Hsp_query-from>
      <Hsp_query-to>2187</Hsp_query-to>
      <Hsp_hit-from>18</Hsp_hit-from>
      <Hsp_hit-to>228</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>211</Hsp_align-len>
      <Hsp_qseq>TVSDYYDVKEEIGRGTFSVV--RRAVHRTTGLEVAAKFVSRAGGRRSEAQRELRILARVSHPR----LACLRDAFQTRRRLIILTELCSGEELLD----RLVKK-PAISELQVHPYIRQILEGVHYLHQSGVLHLDIK----------EVKLCDLGSAQEL--MPPGQPQY--SATGTPEFVAPEIVLQ-QPVSTATDICLSGT--SPFLG</Hsp_qseq>
      <Hsp_hseq>SVDKRFQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLG</Hsp_hseq>
      <Hsp_midline>+V   + + +EIG G + +V   R         VA K V+    +    +R LR L  + H R    + CL D          +  L   EEL++    +++K    +++     +  QIL G+ Y+H + VLH D+K          ++K+CD G A+     P    Q+      T  + APEI+L  Q  + A D+  +G   + FLG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>105</Statistics_hsp-len>
      <Statistics_eff-space>4606492958</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052095-RA transcript Note:&quot;Similar to CTNND2 Catenin delta-2 (Homo sapiens)&quot; offset:0 AED:0.69 eAED:0.69 QI:0|0|0|0.45|1|1|11|0|1106</Iteration_query-def>
  <Iteration_query-len>3321</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2269845469</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052096-RA transcript Note:&quot;Similar to CTNND2 Catenin delta-2 (Homo sapiens)&quot; offset:0 AED:0.48 eAED:0.51 QI:0|0|0|0.62|1|1|8|0|442</Iteration_query-def>
  <Iteration_query-len>1329</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>93</Statistics_hsp-len>
      <Statistics_eff-space>805093450</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052099-RA transcript Note:&quot;Similar to trio Triple functional domain protein (Danio rerio)&quot; offset:0 AED:0.20 eAED:0.20 QI:0|0.08|0.14|0.65|1|1|49|1881|2478</Iteration_query-def>
  <Iteration_query-len>9318</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>130.568</Hsp_bit-score>
      <Hsp_score>327</Hsp_score>
      <Hsp_evalue>1.06483e-30</Hsp_evalue>
      <Hsp_query-from>6601</Hsp_query-from>
      <Hsp_query-to>7293</Hsp_query-to>
      <Hsp_hit-from>204</Hsp_hit-from>
      <Hsp_hit-to>467</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>81</Hsp_identity>
      <Hsp_positive>133</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>267</Hsp_align-len>
      <Hsp_qseq>IGRGRFSVVRRCLQKGSPREVAAKFVSKK--LKRKEQVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAG--------------------YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRGQPVALS-------------TDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDY-SFPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWLQ</Hsp_qseq>
      <Hsp_hseq>VGQGAFATVKKAIERTTGKTFAVKIISKRKVIGNMDGVTRELEVLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDP--VLVKITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGPLKDF-RISEEARDFIDSLLQVDPNNRSTAAKALNHPWIK</Hsp_hseq>
      <Hsp_midline>+G+G F+ V++ +++ + +  A K +SK+  +   + V  E  VL+ L HP++  L   YE + S+ +V+E V+G                      R  L A++Y+H+  I+H D+KP+N+L+E   P  V VK+ D G A       ++    G+  + +PEV+RG+  ++S              D WS+G L YV+L+G  PF   + D+    I R  Y   P + F  +SEEAR F+  LLQ D   R   +  L  PW++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>108.227</Hsp_bit-score>
      <Hsp_score>269</Hsp_score>
      <Hsp_evalue>1.18403e-24</Hsp_evalue>
      <Hsp_query-from>6601</Hsp_query-from>
      <Hsp_query-to>7338</Hsp_query-to>
      <Hsp_hit-from>53</Hsp_hit-from>
      <Hsp_hit-to>325</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>79</Hsp_identity>
      <Hsp_positive>127</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>275</Hsp_align-len>
      <Hsp_qseq>IGRGRFSVVRRCLQKGSPREVAAKFVSKKLKRKEQVA-----HEAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAG--------------------YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQIT-THYYVHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVD---ETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWLQCPGYAYPGALLDVAR</Hsp_qseq>
      <Hsp_hseq>LGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLV-IADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSPFIAESVEGFMEEC-TASRYPVTFHMPYWDNISIDVKRFILKALRLNPADRPTATELLDDPWITSKRVETSNILPDVKK</Hsp_hseq>
      <Hsp_midline>+G G F VVR+  +  +  +VA K + KK  +   V       E ++L+ L HP + S  D +E+   F +V +L  G                     +   L A++Y+H+  + H D+KPEN+L    S ++  V + D G A Q+      ++   GS  + +PEV+         D WS+GV+ Y LL G SPF+ ESV+   E C    R   +F   Y+ ++S + + F+   L+ + A RP  +  L DPW+          L DV +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>108.227</Hsp_bit-score>
      <Hsp_score>269</Hsp_score>
      <Hsp_evalue>1.30508e-24</Hsp_evalue>
      <Hsp_query-from>6601</Hsp_query-from>
      <Hsp_query-to>7296</Hsp_query-to>
      <Hsp_hit-from>43</Hsp_hit-from>
      <Hsp_hit-to>301</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>261</Hsp_align-len>
      <Hsp_qseq>IGRGRFSVVRRCLQKGSPREVAAKFVSKKLKRKEQVAHEA-----AVLRNLQHPQLPSLLDTYETSSSFVLVLELVAG--------------------YLRDTLHALQYLHNCRIAHLDIKPENLL-VEVSSPSAVRVKLVDLGEAVQITT-HYYVHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDY--SFPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWLQC</Hsp_qseq>
      <Hsp_hseq>LGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVV--ADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAELLEDPWIIC</Hsp_hseq>
      <Hsp_midline>+G G F VVR+     +  +VA K + KK  +  +V  EA      +L+ L HP + +  D +E+   F ++ +L  G                     L + L A++Y+H+  I H D+KPENLL ++ S  S + V   D G A ++ +    ++   GS  + +PEV+         D WS+GV+ Y LL G S F  E V +        +Y   F   Y+ SVS +A+ F+   L  D ++RP  +  L DPW+ C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>105.531</Hsp_bit-score>
      <Hsp_score>262</Hsp_score>
      <Hsp_evalue>3.76328e-23</Hsp_evalue>
      <Hsp_query-from>6580</Hsp_query-from>
      <Hsp_query-to>7323</Hsp_query-to>
      <Hsp_hit-from>54</Hsp_hit-from>
      <Hsp_hit-to>319</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>124</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>274</Hsp_align-len>
      <Hsp_qseq>TYAELAEIGRGRFSVVRRCLQKGSPREVAAKFVSKKLKRKE----QVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAGYLRD-------------------TLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRGQPVA-LSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWLQC--PGYAYPGAL</Hsp_qseq>
      <Hsp_hseq>NYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLD----EHLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPK----FLSPGAAGLIKRMLIVNPLNRISIHEIMQDDWFKVDLPEYLLPPDL</Hsp_hseq>
      <Hsp_midline> Y  +  +G G F  V+      + ++VA K ++KK+  K     ++  E + LR L+HP +  L D  ++    ++V+E     L D                    + A++Y H  +I H D+KPENLL++      + VK+ D G +  +T   ++    GSP +A+PEV+ G+  A    D WS GV+ YV+L    PF DES+     NI    Y+ P+     +S  A   ++ +L  +   R      + D W +   P Y  P  L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>97.4413</Hsp_bit-score>
      <Hsp_score>241</Hsp_score>
      <Hsp_evalue>2.93402e-21</Hsp_evalue>
      <Hsp_query-from>6577</Hsp_query-from>
      <Hsp_query-to>7254</Hsp_query-to>
      <Hsp_hit-from>86</Hsp_hit-from>
      <Hsp_hit-to>325</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>250</Hsp_align-len>
      <Hsp_qseq>STYAELAEIGRGRFSVVRRCLQKGSPREVAAKFVSK----KLKRKEQVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAG--------------------YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARR</Hsp_qseq>
      <Hsp_hseq>SDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNG----HIKITDFGFAKYVPDVTYT--LCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHP----DAQDLLKKLITRDLSER</Hsp_hseq>
      <Hsp_midline>S +  L  +G G F  V       + R  A K + K    KLK+ E    E  +L  + HP +  +  T++ S    +V++ + G                    Y  +   AL+YLH+  I + D+KPEN+L++ +      +K+ D G A  +    Y   L G+P++ +PEVV  +P   S D WS GVL Y +L+G +PF + +  +T  NI   +  FP  +      +A+  ++ L+  D + R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>98.5969</Hsp_bit-score>
      <Hsp_score>244</Hsp_score>
      <Hsp_evalue>3.49346e-21</Hsp_evalue>
      <Hsp_query-from>6571</Hsp_query-from>
      <Hsp_query-to>7290</Hsp_query-to>
      <Hsp_hit-from>196</Hsp_hit-from>
      <Hsp_hit-to>480</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>122</Hsp_positive>
      <Hsp_gaps>51</Hsp_gaps>
      <Hsp_align-len>288</Hsp_align-len>
      <Hsp_qseq>FDSTYAELAEIGRGRFSVVRRCLQKGSPREVAAKFV----SKKLKRKEQVAHEAAVLRNLQHPQLPSLLDTY-----ETSSSFVLVLELV--------------------AGYLRDTLHALQYLHNCRIAHLDIKPENLLVEVS---SPSAVR------------VKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDE----SVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWL</Hsp_qseq>
      <Hsp_hseq>FFDKYLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVILYVCLCGFPPFSDQLGPPSLKE---QILQAKYAFYSPYWDKIDDSVLHLISNLLVLNPDERYNIDEALNHPWF</Hsp_hseq>
      <Hsp_midline>F   Y    E+G G +++V+    K + ++VA K      +   K+ +Q   E  +L  +QHP + +LLD++     ++     LVLE +                        +  L  L+YLH   I H DIKPEN+L+ ++   +PS V+            VK+ D G A       + + L G+P + +PEV+  +      D WS GV+ YV L G  PF D+    S+ E    I +  Y+F   Y+  + +     +  LL  +   R      L  PW </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>96.6709</Hsp_bit-score>
      <Hsp_score>239</Hsp_score>
      <Hsp_evalue>3.51885e-21</Hsp_evalue>
      <Hsp_query-from>6592</Hsp_query-from>
      <Hsp_query-to>7254</Hsp_query-to>
      <Hsp_hit-from>73</Hsp_hit-from>
      <Hsp_hit-to>307</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>245</Hsp_align-len>
      <Hsp_qseq>LAEIGRGRFSVVRRCLQKGSPREVAAKFVSK----KLKRKEQVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAG--------------------YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARR</Hsp_qseq>
      <Hsp_hseq>MRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNG----HIKITDFGFAKEVQTVTWT--LCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVD----LLSKLITADLTRR</Hsp_hseq>
      <Hsp_midline>+  +G G F  V       + R  A K + K    K+K+ E    E  +L+ ++HP L  +  T++ + +  +V++ + G                    Y  + + AL+YLH   I + D+KPEN+L++ +      +K+ D G A ++ T  +   L G+P++ +PEV+  +P   S D WSLGVL Y +L+G +PF D +  +T   I +    +P  +   V +     +  L+  D  RR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.1301</Hsp_bit-score>
      <Hsp_score>235</Hsp_score>
      <Hsp_evalue>1.48509e-20</Hsp_evalue>
      <Hsp_query-from>6592</Hsp_query-from>
      <Hsp_query-to>7254</Hsp_query-to>
      <Hsp_hit-from>90</Hsp_hit-from>
      <Hsp_hit-to>324</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>245</Hsp_align-len>
      <Hsp_qseq>LAEIGRGRFSVVRRCLQKGSPREVAAKFVSK----KLKRKEQVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAG--------------------YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARR</Hsp_qseq>
      <Hsp_hseq>LRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNG----HIKITDFGFAKYVPDVTYT--LCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFP----PFFNEDVKDLLSRLITRDLSQR</Hsp_hseq>
      <Hsp_midline>L  +G G F  V     + + R  A K + K    +LK+ E    E  +L  + HP +  +  T++ +    ++++ + G                    Y  +   AL+YLH+  I + D+KPEN+L++ +      +K+ D G A  +    Y   L G+P++ +PEVV  +P   S D WS G+L Y +L+G +PF D +  +T   I   +  FP       +E+ +  +  L+  D ++R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>97.0561</Hsp_bit-score>
      <Hsp_score>240</Hsp_score>
      <Hsp_evalue>3.36402e-20</Hsp_evalue>
      <Hsp_query-from>6706</Hsp_query-from>
      <Hsp_query-to>7293</Hsp_query-to>
      <Hsp_hit-from>161</Hsp_hit-from>
      <Hsp_hit-to>370</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>217</Hsp_align-len>
      <Hsp_qseq>VAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAG--------------------YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRGQPV-ALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWLQ</Hsp_qseq>
      <Hsp_hseq>IEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKN---RRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMP----SNLSSEARDLISKILVIDPEKRITTQEILKHPLIK</Hsp_hseq>
      <Hsp_midline>+  E  +++ + H  + +L + +E  S   LVLE V G                    Y +  +  + Y H+  I H D+KPENLL++  +    R+K+ D G A     +  +    GSP +ASPE+V G+P     +D WS G++ + LL+G  PF D+++ +  L +    Y  P    +++S EAR  +  +L  D  +R      L  P ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>97.0561</Hsp_bit-score>
      <Hsp_score>240</Hsp_score>
      <Hsp_evalue>3.77646e-20</Hsp_evalue>
      <Hsp_query-from>6706</Hsp_query-from>
      <Hsp_query-to>7314</Hsp_query-to>
      <Hsp_hit-from>78</Hsp_hit-from>
      <Hsp_hit-to>293</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>226</Hsp_align-len>
      <Hsp_qseq>VAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAG--------------------YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRGQPV-ALSTDAWSLGVLAYVLLSGVSPFLDE--SVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWLQCPGYAYP</Hsp_qseq>
      <Hsp_hseq>IEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLD----HKYNIKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSD--DEISREAQDLIRKILTVDPERRIKTRDILKHPLLQ----KYP</Hsp_hseq>
      <Hsp_midline>+  E  +++ L HP +  L D +ET++   LVLE                        + R  +  + Y H   I H D+KPENLL++        +K+ D G A   T    +    GSP +A+PE+V G P    ++D WS GV+ + LL+G  PF +E  ++    L + + ++  P +    +S EA+  +R +L  D  RR      L  P LQ     YP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.2041</Hsp_bit-score>
      <Hsp_score>230</Hsp_score>
      <Hsp_evalue>3.94395e-20</Hsp_evalue>
      <Hsp_query-from>6697</Hsp_query-from>
      <Hsp_query-to>7290</Hsp_query-to>
      <Hsp_hit-from>146</Hsp_hit-from>
      <Hsp_hit-to>355</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>218</Hsp_align-len>
      <Hsp_qseq>KEQVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLE--------------------LVAGYLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWL</Hsp_qseq>
      <Hsp_hseq>QKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNV----IKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMP----SNISQDAQDLILKLLKYDPKDRMRLGDVKMHPWI</Hsp_hseq>
      <Hsp_midline>++Q   E  +  +L HP L      +       L++E                    L + Y+    +AL Y+H   I H DIKPEN+L+  ++     +KL D G ++          + G+ ++ SPE+V  +    + DAW+LGVLA+ LL+G  PF +E  D T   I  LD   P    +++S++A+  +  LL+ D   R       + PW+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>89.7373</Hsp_bit-score>
      <Hsp_score>221</Hsp_score>
      <Hsp_evalue>3.49691e-18</Hsp_evalue>
      <Hsp_query-from>6583</Hsp_query-from>
      <Hsp_query-to>7296</Hsp_query-to>
      <Hsp_hit-from>163</Hsp_hit-from>
      <Hsp_hit-to>480</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>130</Hsp_positive>
      <Hsp_gaps>82</Hsp_gaps>
      <Hsp_align-len>319</Hsp_align-len>
      <Hsp_qseq>YAELAEIGRGRFSVVRRCL-QKGSPRE--------VAAKFVSK--------------------KLKRKEQVAHEAAVLRNLQH--PQLPSLLDTYETSSSFVLVLELVAG-----------YLRDTLH---------ALQYLHNCRIAHLDIKPENLLVE-------------------------VSSPSAVRV-----KLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWLQC</Hsp_qseq>
      <Hsp_hseq>YKLINKIGEGAFSKVFRAIPAKNSSNEFLTKNYKAVAIKVIKKADLSSINGDHRKKDKGKDSTKTSSRDQVLKEVALHKTVSAGCSQIVAFIDFQETDSYYYIIQELLTGGEIFGEIVRLTYFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKN-TKTPCGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTMLCGFPPFYDEKIDTLTEKISRGEYTFLKPWWDEISAGAKNAVAKLLELEPSKRYDIDQFLDDPWLNT</Hsp_hseq>
      <Hsp_midline>Y  + +IG G FS V R +  K S  E        VA K + K                    K   ++QV  E A+ + +     Q+ + +D  ET S + ++ EL+ G           Y  + L          A++++H+  + H DIKPENLL E                         + +P          KL D G + QI +        G+  + +PEVV+ +  ++  D W +G + Y +L G  PF DE +D     I R +Y+F + ++  +S  A++ V  LL+ + ++R      L DPWL  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.1225</Hsp_bit-score>
      <Hsp_score>222</Hsp_score>
      <Hsp_evalue>4.28716e-18</Hsp_evalue>
      <Hsp_query-from>6670</Hsp_query-from>
      <Hsp_query-to>7311</Hsp_query-to>
      <Hsp_hit-from>158</Hsp_hit-from>
      <Hsp_hit-to>383</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>235</Hsp_align-len>
      <Hsp_qseq>KFVSKKLKRKEQVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAG--------------------YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRGQP-VALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWLQCPGYAY</Hsp_qseq>
      <Hsp_hseq>KRLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMIS----SSGEIKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYP----SHLSIEVISLLTRMIVVDPLRRATLKNVVEHPWMNR-GYDF</Hsp_hseq>
      <Hsp_midline>K + K++ R ++   EA++ + L HP +  L +    S+ F ++ E V+G                    + R    ALQYLH   I H D+K EN+++     S+  +K++D G +        +H   GS  FA+PE+++ QP      D WS G++ YVL+ G  PF DE+       I +    +P    + +S E  S +  ++  D  RR      +  PW+   GY +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.1225</Hsp_bit-score>
      <Hsp_score>222</Hsp_score>
      <Hsp_evalue>4.33463e-18</Hsp_evalue>
      <Hsp_query-from>6703</Hsp_query-from>
      <Hsp_query-to>7293</Hsp_query-to>
      <Hsp_hit-from>73</Hsp_hit-from>
      <Hsp_hit-to>286</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>220</Hsp_align-len>
      <Hsp_qseq>QVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLE---------LVAGY-----------LRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRGQPV-ALSTDAWSLGVLAYVLLSGVSPFLDE--SVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWLQ</Hsp_qseq>
      <Hsp_hseq>NIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLD----SFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPND--TEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLK</Hsp_hseq>
      <Hsp_midline> +  E  +++ L HP + SL D +ET+++  L+LE         L+  +            R  +  + Y H   I H D+KPENLL++    S   +K+ D G A   T    +    GSP +A+PE+V G P    ++D WS GV+ + LL+G  PF +E  +V +  L + +  +  P +    +S +A+  +  +L  D  +R      L  P L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.1965</Hsp_bit-score>
      <Hsp_score>217</Hsp_score>
      <Hsp_evalue>1.02515e-17</Hsp_evalue>
      <Hsp_query-from>6601</Hsp_query-from>
      <Hsp_query-to>7293</Hsp_query-to>
      <Hsp_hit-from>88</Hsp_hit-from>
      <Hsp_hit-to>338</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>121</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>260</Hsp_align-len>
      <Hsp_qseq>IGRGRFSVVRRCLQ-KGSPREV-AAKFVSK----KLKRKEQVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLELV-AGYLRDTLH-------------------ALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLG-EAVQITTHYYVHVLLGSPEFASPEVVRGQPV--ALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWLQ</Hsp_qseq>
      <Hsp_hseq>LGEGGFA---RCFQIKDDSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFD----SNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRD--KPISDEGKILIRDILSLDPIERPSLTEIMDYVWFR</Hsp_hseq>
      <Hsp_midline>+G G F+   RC Q K    E+ AAK V+K      K ++++  E  + +++ HP +   +D +E  S+  ++LE+   G L + L                    A++Y+H+ R+ H D+K  N+  +    S   +K+ D G  AV        + + G+P + +PEV+ G+    +   D WSLGV+ Y LL G  PF    V+     I   D+SFP +    +S+E +  +R +L  D   RP  +  +   W +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.8113</Hsp_bit-score>
      <Hsp_score>216</Hsp_score>
      <Hsp_evalue>1.49104e-17</Hsp_evalue>
      <Hsp_query-from>6580</Hsp_query-from>
      <Hsp_query-to>7254</Hsp_query-to>
      <Hsp_hit-from>323</Hsp_hit-from>
      <Hsp_hit-to>586</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>119</Hsp_positive>
      <Hsp_gaps>51</Hsp_gaps>
      <Hsp_align-len>270</Hsp_align-len>
      <Hsp_qseq>TYAELAEIGRGRFSVVRRCLQKGSPREVAAKFVSK----KLKRKEQVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAG----------------------YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTH-------------------YYVHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARR</Hsp_qseq>
      <Hsp_hseq>SFEKIRLLGQGDVGKVYLVRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSG----HVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKFPHD--KEVSKNCKDLIKKLLNKNEAKR</Hsp_hseq>
      <Hsp_midline>++ ++  +G+G    V    ++ + +  A K ++K    K K+ ++V  E  +L    HP + +L  +++T     L +E   G                      Y  + + AL+YLH     + D+KPEN+L+  S      V L D   ++Q T                     +  +  +G+ E+ +PEV+RG     + D W+LG+L Y +L G +PF  ++ +ET  NI   D  FP +    VS+  +  ++ LL  + A+R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.5001</Hsp_bit-score>
      <Hsp_score>210</Hsp_score>
      <Hsp_evalue>4.48508e-17</Hsp_evalue>
      <Hsp_query-from>6652</Hsp_query-from>
      <Hsp_query-to>7290</Hsp_query-to>
      <Hsp_hit-from>193</Hsp_hit-from>
      <Hsp_hit-to>444</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>256</Hsp_align-len>
      <Hsp_qseq>PREVAAKFVSKKLKRKEQVAHEAAVLRNLQHPQLPSLLDTY-ETSSSFVLVLELVAG-----YLR------------------DTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHY-YVHVLLGSPEFASPEV-VRGQPVALST----------------DAWSLGVLAYVLLSGVSPFLDESVDETCLNICRL-DYSFPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWL</Hsp_qseq>
      <Hsp_hseq>PENYAVKIIKLKPNKFDK---EARILLRLDHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEP-CTRIVLADFGIAKDLNSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGISPFYGDGSERSIIQNAKIGKLNFKLKQWDIVSDNAKSFVKDLLQTDVVKRLNSKQGLKHIWI</Hsp_hseq>
      <Hsp_midline>P   A K +  K  + ++   EA +L  L HP +  +  T+ + ++   +  +L+ G     YL                     L AL YLH+  I H D+K +N+L+    P   R+ L D G A  + ++   +H ++G+PE+ +PEV  R    A  +                D WSLGV+ +++L+G+SPF  +  + + +   ++   +F  + +  VS+ A+SFV+ LLQ D  +R      L   W+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.6557</Hsp_bit-score>
      <Hsp_score>213</Hsp_score>
      <Hsp_evalue>4.73676e-17</Hsp_evalue>
      <Hsp_query-from>6583</Hsp_query-from>
      <Hsp_query-to>7128</Hsp_query-to>
      <Hsp_hit-from>620</Hsp_hit-from>
      <Hsp_hit-to>818</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>203</Hsp_align-len>
      <Hsp_qseq>YAELAEIGRGRFSVVRRCLQKGSPREVAAKFVS-KKLKRKEQVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAG-------------------YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITT-HYYVHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDES</Hsp_qseq>
      <Hsp_hseq>YANLVKIGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKELIINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVTHCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEG----DIKLTDFGFCAQINELNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPPYLNET</Hsp_hseq>
      <Hsp_midline>YA L +IG+G    V    + G+   VA K ++ +K  +KE + +E  V++  +HP + + +D+Y       +++E + G                     R+TL  L++LH+  + H DIK +N+L+ +       +KL D G   QI   +     ++G+P + +PEVV  +      D WSLG++   ++ G  P+L+E+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>84.3445</Hsp_bit-score>
      <Hsp_score>207</Hsp_score>
      <Hsp_evalue>2.36948e-16</Hsp_evalue>
      <Hsp_query-from>6580</Hsp_query-from>
      <Hsp_query-to>7281</Hsp_query-to>
      <Hsp_hit-from>495</Hsp_hit-from>
      <Hsp_hit-to>770</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>119</Hsp_positive>
      <Hsp_gaps>54</Hsp_gaps>
      <Hsp_align-len>282</Hsp_align-len>
      <Hsp_qseq>TYAELAEIGRGRFSVVRRCLQKGSPREVAAKFVSK----KLKRKEQVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAG----------------------YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQI----------------------TTHYYVHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLD</Hsp_qseq>
      <Hsp_hseq>SFEKIRLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSG----HIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKNEVSFPNN--NEISRTCKDLIKKLLTKNESKRLGCKMGAAD</Hsp_hseq>
      <Hsp_midline>++ ++  +G+G    V    +K + R  A K +SK    K  + ++V  E  +L    HP + +L  ++++     L +E   G                      Y  +   AL+YLH     + D+KPEN+L+  S      + L D   ++Q                       +  +  +  +G+ E+ +PEV+RG     + D W+LG+L Y +L G +PF  ++ +ET  NI + + SFP      +S   +  ++ LL  + ++R  C     D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.4185</Hsp_bit-score>
      <Hsp_score>202</Hsp_score>
      <Hsp_evalue>8.95476e-16</Hsp_evalue>
      <Hsp_query-from>6670</Hsp_query-from>
      <Hsp_query-to>7290</Hsp_query-to>
      <Hsp_hit-from>179</Hsp_hit-from>
      <Hsp_hit-to>398</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>228</Hsp_align-len>
      <Hsp_qseq>KFVSKKLKRKEQVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAG--------------------YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRGQP-VALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWL</Hsp_qseq>
      <Hsp_hseq>KKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSS----EIKIIDFGLSNIYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKIKQGKVEYPQH----LSIEVISLLSKMLVVDPKRRATLKQVVEHHWM</Hsp_hseq>
      <Hsp_midline>K + K++ R ++   EA++ + L HP +  L +    S+ F ++ E V+G                    + R    AL YLH   I H D+K EN+++  SS     +K++D G +    +   +H   GS  FA+PE+++  P      D WS GV+ +VL+ G  PF DE+       I +    +P+     +S E  S +  +L  D  RR      +   W+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.6481</Hsp_bit-score>
      <Hsp_score>200</Hsp_score>
      <Hsp_evalue>1.01105e-15</Hsp_evalue>
      <Hsp_query-from>6565</Hsp_query-from>
      <Hsp_query-to>7254</Hsp_query-to>
      <Hsp_hit-from>345</Hsp_hit-from>
      <Hsp_hit-to>587</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>255</Hsp_align-len>
      <Hsp_qseq>DNFDSTYAELAEIGRGRFSVVRRCLQKGSPREVAAKFVSKK-LKRKEQVAH---EAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAG--------------------YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGE-AVQITTHYYVHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARR</Hsp_qseq>
      <Hsp_hseq>DDFDL----LKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQG----HIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGF----DRDAKDLLIGLLSRDPTRR</Hsp_hseq>
      <Hsp_midline>D+FD     L  IG+G F  V +  +K + +  A K + K  +  K +V H   E  VL  +  P +  L  ++++      VL  + G                    Y  + L AL  LH   + + D+KPEN+L++        + L D G   + +          G+PE+ +PE++ G     + D W+LGVL Y +L+G+ P+ DE V +    I +    FP+ +      +A+  +  LL  D  RR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.6481</Hsp_bit-score>
      <Hsp_score>200</Hsp_score>
      <Hsp_evalue>1.23533e-15</Hsp_evalue>
      <Hsp_query-from>6565</Hsp_query-from>
      <Hsp_query-to>7254</Hsp_query-to>
      <Hsp_hit-from>342</Hsp_hit-from>
      <Hsp_hit-to>584</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>255</Hsp_align-len>
      <Hsp_qseq>DNFDSTYAELAEIGRGRFSVVRRCLQKGSPREVAAKFVSKK-LKRKEQVAH---EAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAG--------------------YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGE-AVQITTHYYVHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARR</Hsp_qseq>
      <Hsp_hseq>DDFDL----LKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQG----HIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGF----DPAAKDLLIGLLSRDPSRR</Hsp_hseq>
      <Hsp_midline>D+FD     L  IG+G F  V +  +K + +  A K + K  +  K +V H   E  VL  +  P +  L  ++++     LVL  + G                    Y+ + L AL  LH   + + D+KPEN+L++        + L D G   + +  +       G+PE+ +PE++ GQ    + D W+LG+L Y +++G+ P+ DE+V      I +    FP+ +       A+  +  LL  D +RR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.7221</Hsp_bit-score>
      <Hsp_score>195</Hsp_score>
      <Hsp_evalue>2.80398e-15</Hsp_evalue>
      <Hsp_query-from>6580</Hsp_query-from>
      <Hsp_query-to>7293</Hsp_query-to>
      <Hsp_hit-from>120</Hsp_hit-from>
      <Hsp_hit-to>415</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>124</Hsp_positive>
      <Hsp_gaps>60</Hsp_gaps>
      <Hsp_align-len>297</Hsp_align-len>
      <Hsp_qseq>TYAELAEIGRGRFSVVRRCLQKGSPRE--VAAKFVSKK-------LK--------RKEQVAHEAAV--LRNLQHPQLPSLLDTYETSSSFVLVLELVAG--------------------YLRDTLHALQYLHNCRIAHLDIKPENLLVE--------------------VSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWLQ</Hsp_qseq>
      <Hsp_hseq>NYKLLNKIGEGAFSRVFKAVGINTDDQAPVAIKAIIKKGISSDAILKGNDRIQGSSRKKVLNEVAIHKLVSKNNPHCTKFIAFQESANYYYLVTELVTGGEIFDRIVQLTCFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLRNNT-AKTPCGTIEYVASEVFTSKRYSMKVDMWSIGCVLFTLLCGYPPFYEKNEKTLLKKISRGDYEFLAPWWDNISSGAKNAVTHLLEVDPNKRYDIDDFLNDPWLN</Hsp_hseq>
      <Hsp_midline> Y  L +IG G FS V + +   +  +  VA K + KK       LK         +++V +E A+  L +  +P     +   E+++ + LV ELV G                     +     A++++H   I H D+KPENLL E                    V       VKL+D G A ++  +       G+ E+ + EV   +  ++  D WS+G + + LL G  PF +++       I R DY F   ++ ++S  A++ V  LL+ D  +R      L DPWL </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.1073</Hsp_bit-score>
      <Hsp_score>196</Hsp_score>
      <Hsp_evalue>4.38418e-15</Hsp_evalue>
      <Hsp_query-from>6580</Hsp_query-from>
      <Hsp_query-to>7254</Hsp_query-to>
      <Hsp_hit-from>23</Hsp_hit-from>
      <Hsp_hit-to>313</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>119</Hsp_positive>
      <Hsp_gaps>74</Hsp_gaps>
      <Hsp_align-len>295</Hsp_align-len>
      <Hsp_qseq>TYAELAEIGRGRFSVVRRC-LQKGSPREVAAKFVSK-KLKRK---EQVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLE--------------------------------------------LVAGYLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSP-------------------SAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLD--YSFPEEYFASVSEEARSFVRLLLQGDYARR</Hsp_qseq>
      <Hsp_hseq>NYTAEKEIGKGSFATVYRGHLTSDKSQHVAIKEVSRAKLKNKKLLENLEIEIAILKKIKHPHIVGLIDCERTSTDFYLIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLL--STPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVVFEMCCGTPPFRASNHLELFKKIKRANDVITFPS--YCNIEPELKELICSLLTFDPAQR</Hsp_hseq>
      <Hsp_midline> Y    EIG+G F+ V R  L     + VA K VS+ KLK K   E +  E A+L+ ++HP +  L+D   TS+ F L++E                                             V  YL+    AL++L +  + H DIKP+NLL+  S+P                   +   +K+ D G A  +        L GSP + +PE++  Q      D WS+G + + +  G  PF   +  E    I R +   +FP   + ++  E +  +  LL  D A+R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.337</Hsp_bit-score>
      <Hsp_score>194</Hsp_score>
      <Hsp_evalue>4.68456e-15</Hsp_evalue>
      <Hsp_query-from>6601</Hsp_query-from>
      <Hsp_query-to>7290</Hsp_query-to>
      <Hsp_hit-from>21</Hsp_hit-from>
      <Hsp_hit-to>281</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>121</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>265</Hsp_align-len>
      <Hsp_qseq>IGRGRFSVVRRC-LQKGSPREVAAKFVS----KKLKRKEQVAHEAAVLRNL--QHPQLPSLLDTYETSSSFVLVLELVAG--------------------YLRDTLHALQYLH-NCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQIT----THYYVHVLLGSPEFASPEVVRGQP--VALSTDAWSLGVLAYVLLSGVSPF-LDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWL</Hsp_qseq>
      <Hsp_hseq>VGQGAFACVKNAHLQMDPSIILAVKFIHVPTCKKMGLSDKDITKEVVLQSKCSKHPNVLRLIDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENILLDKNG----NLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQTPWELPSLENEDFVFFIENDGNLNWGPWSKIEFTHLNLLRKILQPDPNKRVTLKALKLHPWV</Hsp_hseq>
      <Hsp_midline>+G+G F+ V+   LQ      +A KF+     KK+   ++   +  VL++   +HP +  L+D   +     ++LE+  G                    Y +  + A+ YLH  C +AH DIKPEN+L++ +      +KL D G A Q      T        GSP + +PEV+  +    A  TD WS+G+L +VLL+G +P+ L    +E  +     D +     ++ +     + +R +LQ D  +R    A  L PW+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.7221</Hsp_bit-score>
      <Hsp_score>195</Hsp_score>
      <Hsp_evalue>5.21116e-15</Hsp_evalue>
      <Hsp_query-from>6601</Hsp_query-from>
      <Hsp_query-to>7254</Hsp_query-to>
      <Hsp_hit-from>418</Hsp_hit-from>
      <Hsp_hit-to>655</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>247</Hsp_align-len>
      <Hsp_qseq>IGRGRFSVVRRCLQKGSPREVAAKFVSKK-LKRKEQVAHEAAVLRNL-------QHPQLPSLLDTYETSSSFVLVLELVAG--------------------YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRGQP-VALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARR</Hsp_qseq>
      <Hsp_hseq>LGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGE-RNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANG----NIALCDFGLS-KADLKDRTNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDV---LSQEGRSFVKGLLNRNPKHR</Hsp_hseq>
      <Hsp_midline>+G+G F  V +  +K + R  A K +SKK + +K ++AH     RN+         P +  L  +++T +   LV + ++G                    Y+ + + AL++LH+  I + D+KPEN+L++ +      + L D G + +       +   G+ E+ +PE++  +       D WSLGVL + +  G SPF  E+  +    I      FP +    +S+E RSFV+ LL  +   R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.0258</Hsp_bit-score>
      <Hsp_score>188</Hsp_score>
      <Hsp_evalue>3.50611e-14</Hsp_evalue>
      <Hsp_query-from>6658</Hsp_query-from>
      <Hsp_query-to>7125</Hsp_query-to>
      <Hsp_hit-from>590</Hsp_hit-from>
      <Hsp_hit-to>771</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>186</Hsp_align-len>
      <Hsp_qseq>EVAAK-FVSKKLKRKEQVAHEAAVLRNLQHPQLPSLLDTY-ETSSSFVLVLELVAG---------------------------YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVH-VLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDE</Hsp_qseq>
      <Hsp_hseq>KVAIKQMVLSKQPRKELIVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLD----TRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYLNE</Hsp_hseq>
      <Hsp_midline>+VA K  V  K  RKE + +E  V+++ +H  + + L+ Y  T     +V+E + G                            +R+T   L++LH+  I H DIK +N+L++    +  RVK+ D G   ++T        ++G+P + +PEVV+ +      D WSLG++   +L G  P+L+E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.485</Hsp_bit-score>
      <Hsp_score>184</Hsp_score>
      <Hsp_evalue>9.75382e-14</Hsp_evalue>
      <Hsp_query-from>6580</Hsp_query-from>
      <Hsp_query-to>7302</Hsp_query-to>
      <Hsp_hit-from>40</Hsp_hit-from>
      <Hsp_hit-to>291</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>262</Hsp_align-len>
      <Hsp_qseq>TYAELAEIGRGRFSVVRRCLQKGSPREVAAKFVSKKLKRKEQVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAGY-LRDTLH-------------------ALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVV-RGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWLQCPG</Hsp_qseq>
      <Hsp_hseq>NYKILKQIGEGSFGKVYLALHRPTHRKVCLKTSDKN---DPNIVREVFYHRQFDFPYITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSMHCVHRDLKLENILLDKNG----NAKLTDFGFTRECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEE---PKYDAKVIPDDARDLISRLLAKNPGERPSLSQVLRHPFLQPYG</Hsp_hseq>
      <Hsp_midline> Y  L +IG G F  V   L + + R+V  K   K       +  E    R    P +  L +   T S   + LE   G  L D L                    A+ Y H+    H D+K EN+L++ +       KL D G   +  T   +  + G+  + +PE++ R        D WSLGV+ Y L++G  PF D+   +T   I   +   P+     + ++AR  +  LL  +   RP  S  L  P+LQ  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.0998</Hsp_bit-score>
      <Hsp_score>183</Hsp_score>
      <Hsp_evalue>1.51748e-13</Hsp_evalue>
      <Hsp_query-from>6823</Hsp_query-from>
      <Hsp_query-to>7296</Hsp_query-to>
      <Hsp_hit-from>956</Hsp_hit-from>
      <Hsp_hit-to>1101</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>163</Hsp_align-len>
      <Hsp_qseq>LRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVV-----RGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWLQC</Hsp_qseq>
      <Hsp_hseq>FKQVVASIKHLHDQGIVHRDIKDENVIVD----SHGFVKLIDFGSAAYIKSGPF-DVFVGTMDYAAPEVLGGSSYKGKP----QDIWALGVLLYTIIYKENPYYN--IDEILEGELRFDKS------EHVSEECISLIKRILTREVDKRPTIDEIYEDKWLKI</Hsp_hseq>
      <Hsp_midline> +  + ++++LH+  I H DIK EN++V+    S   VKL+D G A  I +  +  V +G+ ++A+PEV+     +G+P     D W+LGVL Y ++   +P+ +  +DE      R D S        VSEE  S ++ +L  +  +RP       D WL+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>1.04577e-12</Hsp_evalue>
      <Hsp_query-from>6799</Hsp_query-from>
      <Hsp_query-to>7290</Hsp_query-to>
      <Hsp_hit-from>314</Hsp_hit-from>
      <Hsp_hit-to>481</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>176</Hsp_align-len>
      <Hsp_qseq>VLELVAGYLRDT-LHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLG---EAVQITTHYYVHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETC--LNICRLDYSF-PE-----EYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWL</Hsp_qseq>
      <Hsp_hseq>ISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKG----EIKLCDFGVSGEAV----NSLAMTFTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRFPFESDKITQNVAPIELLTMILTFSPQLKDEPELDISWSKTFRSFIDYCLKKDARERPSPRQMLKHPWI</Hsp_hseq>
      <Hsp_midline>+ E V G + ++ L  L YLH  ++ H DIKP+N+L+         +KL D G   EAV    +       G+  + +PE ++GQP +++ D WSLG+    +  G  PF  + + +    + +  +  +F P+     E   S S+  RSF+   L+ D   RP     L  PW+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.8626</Hsp_bit-score>
      <Hsp_score>172</Hsp_score>
      <Hsp_evalue>3.22013e-12</Hsp_evalue>
      <Hsp_query-from>6577</Hsp_query-from>
      <Hsp_query-to>7290</Hsp_query-to>
      <Hsp_hit-from>1094</Hsp_hit-from>
      <Hsp_hit-to>1354</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>274</Hsp_align-len>
      <Hsp_qseq>STYAELAEIGRGRFSVVRRCLQKGSPREVAAKFVSK---------KLKRKEQVAHEAAVLRNLQ---HPQLPSLLDTYETSSSFVL---------------VLELVAGY--------LRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRGQPV-ALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWL</Hsp_qseq>
      <Hsp_hseq>SDFVSLQKMGEGAYGKVNLCIHKKNRYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKKPHENILRLLDFFEDDDYYYIETPVHGETGCIDLFDLIEFKTNMTEFEAKLIFKQVVAGIKHLHDQGIVHRDIKDENVIVD----SKGFVKIIDFGSAAYVKSGPF-DVFVGTIDYAAPEVLGGNPYEGQPQDIWAIGILLYTVVFKENPFYN--IDE----ILEGDLKFNNA--EEVSEDCIELIKSILNRCVPKRPTIDDINNDKWL</Hsp_hseq>
      <Hsp_midline>S +  L ++G G +  V  C+ K +   V  K + K         + ++   +  E  ++  L    H  +  LLD +E    + +               ++E              +  +  +++LH+  I H DIK EN++V+    S   VK++D G A  + +  +  V +G+ ++A+PEV+ G P      D W++G+L Y ++   +PF +  +DE    I   D  F       VSE+    ++ +L     +RP       D WL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>3.53619e-12</Hsp_evalue>
      <Hsp_query-from>6691</Hsp_query-from>
      <Hsp_query-to>7290</Hsp_query-to>
      <Hsp_hit-from>496</Hsp_hit-from>
      <Hsp_hit-to>712</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>KRKEQVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLE--------------------LVAGYLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQIT----THYYVHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWL</Hsp_qseq>
      <Hsp_hseq>KMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGC----VKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQA---IFKIGTNTTPEIPSWATSEGKNFLRKAFELDYQYRPSALELLQHPWL</Hsp_hseq>
      <Hsp_midline>K  + + HE  +L+ L H  + +     +   +  + LE                    L+  + R  L  + YLH   I H DIK  N+L+++       VK+ D G + +++           L GS  + SPEVV+        D WS G +   + +G  PF D S  +    I ++  +   E  +  + E ++F+R   + DY  RP     L  PWL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>4.30785e-12</Hsp_evalue>
      <Hsp_query-from>6601</Hsp_query-from>
      <Hsp_query-to>7293</Hsp_query-to>
      <Hsp_hit-from>52</Hsp_hit-from>
      <Hsp_hit-to>314</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>268</Hsp_align-len>
      <Hsp_qseq>IGRGRFSVVRRCLQKGS-----PREVAAKFVSKKLKRKE-----QVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAG-----------YLRDT---------LHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQI-TTHYYVHVLLGSPEFASPEVVRGQPV--ALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSF----PEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWLQ</Hsp_qseq>
      <Hsp_hseq>LGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHE----NLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARL-YKYITQTPLKFPEYITPIPRDLLRRILVPNPRRRINLQTIKRHVWLK</Hsp_hseq>
      <Hsp_midline>+G G F  V+    K S     P++VA K + +   +K+     ++  E   L++L HP +  L +  + S    +VLE V+G            L+++         +  + Y+H   + H D+K ENLL++        + + D G   +    +  +    GSP +A+PE+V       A   D WS GV+ Y +L+G  P+ D+  + T  +I RL Y +    P ++   ++   R  +R +L  +  RR          WL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>4.54313e-12</Hsp_evalue>
      <Hsp_query-from>6598</Hsp_query-from>
      <Hsp_query-to>7167</Hsp_query-to>
      <Hsp_hit-from>16</Hsp_hit-from>
      <Hsp_hit-to>247</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>236</Hsp_align-len>
      <Hsp_qseq>EIGRGRFSVVRRCLQKGSPREV-AAKFVSKKLKRKEQVAHEAAVLRNL-------QHPQLPSLLDTYETSSSFVLVLELV-AGYLRDTLH-------------------ALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQI------------------TTHYYVHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDY</Hsp_qseq>
      <Hsp_hseq>ELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDG----RLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPFRGENELKTFEKIVALDY</Hsp_hseq>
      <Hsp_midline>E+G G +S V + L K SP ++ A K  SKK   KE       + +N         H  +  L  T+    +   VL+    G L   LH                   AL+++H+  I H D+KPEN+L++       R+ + D G A  I                    +      +G+ E+ SPE++        +D W+LG + Y  + G  PF  E+  +T   I  LDY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>4.91855e-12</Hsp_evalue>
      <Hsp_query-from>6601</Hsp_query-from>
      <Hsp_query-to>7254</Hsp_query-to>
      <Hsp_hit-from>185</Hsp_hit-from>
      <Hsp_hit-to>431</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>255</Hsp_align-len>
      <Hsp_qseq>IGRGRFSVVRRCLQKGSPREVAAKFVSKK-LKRKEQVAH---EAAVLRNLQH-PQLPSLLDTYETSSSFVLVLELVA-----------GYLRDT---------LHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQIT-THYYV-----------HVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARR</Hsp_qseq>
      <Hsp_hseq>IGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLD----GEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKVQYAFTPGFPLII----RDLVKKILVKNLDRR</Hsp_hseq>
      <Hsp_midline>IG G +S V       + +  AAK ++K+ L R+++V +   E   L+ L + P +  L  T++  SS   +LE              G L +T         + A+ YLH+  I H DIKPEN+L++      +++KL D G A  +  T+  V              +G+ E+ SPE++         D W+ G + + +++G  PF   +   T   + ++ Y+F   +   +    R  V+ +L  +  RR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>9.93875e-12</Hsp_evalue>
      <Hsp_query-from>6583</Hsp_query-from>
      <Hsp_query-to>7116</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>222</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>55</Hsp_gaps>
      <Hsp_align-len>227</Hsp_align-len>
      <Hsp_qseq>YAELAEIGRGRFSVVRRCLQKGSPREVAAKFVSKKLKRKEQVAHEAAVLRNLQ----HPQLPSLLDTYETSSSFVLVLELV-AGYLRDTLH---------------------------ALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRGQ---------------PV--ALSTDAWSLGVLAYVLLSGVSPF</Hsp_qseq>
      <Hsp_hseq>YTKLRSIQSGTFSTVYKAWSTTHNRYVALKITPKYKTSEANMKNEYDVMKILSSCNPHPNICSMLDFYTDDSYYIMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQIDMQKIIKQLCSAISFAHSLGIAHRDIKPENILLTINGD----IKLADWGHAIQSPKSNDFQI--GTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFGDCLF</Hsp_hseq>
      <Hsp_midline>Y +L  I  G FS V +       R VA K   K    +  + +E  V++ L     HP + S+LD Y   S +++VLE    G L D L                            A+ + H+  IAH DIKPEN+L+ ++      +KL D G A+Q        +  G+  + +PE   G+               P+      D WSLG   + L+ G   F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YPR111W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:747306:749000:1 gene:YPR111W transcript:YPR111W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF20 description:Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006315]</Hit_def>
  <Hit_accession>YPR111W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.5514</Hsp_bit-score>
      <Hsp_score>166</Hsp_score>
      <Hsp_evalue>9.93884e-12</Hsp_evalue>
      <Hsp_query-from>6592</Hsp_query-from>
      <Hsp_query-to>7152</Hsp_query-to>
      <Hsp_hit-from>172</Hsp_hit-from>
      <Hsp_hit-to>419</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>69</Hsp_gaps>
      <Hsp_align-len>252</Hsp_align-len>
      <Hsp_qseq>LAEIGRGRFSVVRRCLQKGSPREVAAKFVSKKLKRK----EQVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAG--------------------YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLG-----------EAVQI------------------------------TTHYYVHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNI</Hsp_qseq>
      <Hsp_hseq>LTQVGQGGYGQVYLAKKKDSDEICALKILNKKLLFKLNETNHVLTERDILTTTRSDWLVKLLYAFQDPESLYLAMEFVPGGDFRTLLINTRILKSGHARFYISEMFCAVNALHELGYTHRDLKPENFLIDATG----HIKLTDFGLAAGTVSNERIESMKIRLEEVKNLEFPAFTERSIEDRRKIYHNMRKTEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYENL</Hsp_hseq>
      <Hsp_midline>L ++G+G +  V    +K S    A K ++KKL  K      V  E  +L   +   L  LL  ++   S  L +E V G                    Y+ +   A+  LH     H D+KPEN L++ +      +KL D G           E+++I                              T   Y + ++GSP++ + EV+ G+    + D WSLG + +  L G +PF   S +ET  N+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>2.41454e-11</Hsp_evalue>
      <Hsp_query-from>6550</Hsp_query-from>
      <Hsp_query-to>7137</Hsp_query-to>
      <Hsp_hit-from>817</Hsp_hit-from>
      <Hsp_hit-to>1031</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>223</Hsp_align-len>
      <Hsp_qseq>RTVWKDNFDSTYAELAEIGRGRFSVVRRCLQKGSPREVAAKFVSKKLKRKEQVAHEAAVLRNL-------QHPQLPSLLDTYETSSSFVLVLELVAG-------------------YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAV-QITTHYYVHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDE</Hsp_qseq>
      <Hsp_hseq>RKVSLDNF----VLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILL---TPEG-HIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDE</Hsp_hseq>
      <Hsp_midline>R V  DNF      L  +G+G F  V     K + R  A K + K    +      A   + +       +HP L +L  +++T +     +E + G                   Y  + L AL+Y H+  + + D+K EN+L+   +P    +K+ D G    ++          G+PEF +PE+++ Q    + D W+ GVL Y +L   SPF  +  DE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>2.57655e-11</Hsp_evalue>
      <Hsp_query-from>6811</Hsp_query-from>
      <Hsp_query-to>7125</Hsp_query-to>
      <Hsp_hit-from>484</Hsp_hit-from>
      <Hsp_hit-to>585</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>106</Hsp_align-len>
      <Hsp_qseq>VAGYLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVH-VLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDE</Hsp_qseq>
      <Hsp_hseq>MAYIVKETCQGLKFLHNKKIIHRDIKSDNILLN----SQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPPYLNE</Hsp_hseq>
      <Hsp_midline>+A  +++T   L++LHN +I H DIK +N+L+     S   VK+ D G  V++T        ++G+P + +PE+V  +      D WSLG++   ++ G  P+L+E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>3.02333e-11</Hsp_evalue>
      <Hsp_query-from>6559</Hsp_query-from>
      <Hsp_query-to>7293</Hsp_query-to>
      <Hsp_hit-from>212</Hsp_hit-from>
      <Hsp_hit-to>489</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>286</Hsp_align-len>
      <Hsp_qseq>WK-DNFDSTYAELAEIGRGRFSVVRRCLQKGSPREVAAKFVSK---KLKRKEQVAHEAAVLRNLQHPQLPSL--LDTYETSSSFVLVLELVAGYLRD------------------------TLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLG---EAVQITTHYYVHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVD------ETCLNICRLDYSFPEEYFASV--SEEARSFVRLLLQGDYARRPPCSACLLDPWLQ</Hsp_qseq>
      <Hsp_hseq>WKYANLKDRIETLGILGEGAGGSVSKCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQFNRSFQSEYIVRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENG----QVKLCDFGVSGEAV----NSLATTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANGKFPCSSEKMAANIAPFELLMWILTFTPELKDEPESNIIWSPSFKSFIDYCLKKDSRERPSPRQMINHPWIK</Hsp_hseq>
      <Hsp_midline>WK  N       L  +G G    V +C  K   +  A K ++      + ++Q+  E    R+ Q   +     + T + +SS  + +E + G   D                         L  L YLH  ++ H DIKP+N+L+  +     +VKL D G   EAV    +       G+  + +PE ++GQP ++++D WSLG+    + +G  P   E +       E  + I        +E  +++  S   +SF+   L+ D   RP     +  PW++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>7.5176e-11</Hsp_evalue>
      <Hsp_query-from>6598</Hsp_query-from>
      <Hsp_query-to>7242</Hsp_query-to>
      <Hsp_hit-from>130</Hsp_hit-from>
      <Hsp_hit-to>375</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>254</Hsp_align-len>
      <Hsp_qseq>EIGRGRFSVVRRCLQKGSPREVAAKFVSKK-LKRKEQVAH---EAAVLRNLQHPQ-LPSLLDTYETSSSFVLVLE---------LVAGY--LRDT---------LHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTH---------YY-----VHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGD</Hsp_qseq>
      <Hsp_hseq>QLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQKLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKN----MKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKIQYAFT----AGFPQIVKDLVKKLLVRD</Hsp_hseq>
      <Hsp_midline>++G G +S V     + S ++ A K +SK+ L R+++V +   E   L+ L   + +  L  T++  +S   +LE         L+  Y  L +T         + A+  LHN  I H DIKPEN+L++ +    ++VKL D G A  +            Y+         +G+ E+ SPE++         D W+ G + Y +L+G  PF   +   T   + ++ Y+F     A   +  +  V+ LL  D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YMR291W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:852630:854390:1 gene:YMR291W transcript:YMR291W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TDA1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000004905]</Hit_def>
  <Hit_accession>YMR291W</Hit_accession>
  <Hit_len>586</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>1.05837e-10</Hsp_evalue>
      <Hsp_query-from>6601</Hsp_query-from>
      <Hsp_query-to>7293</Hsp_query-to>
      <Hsp_hit-from>45</Hsp_hit-from>
      <Hsp_hit-to>352</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>118</Hsp_positive>
      <Hsp_gaps>77</Hsp_gaps>
      <Hsp_align-len>308</Hsp_align-len>
      <Hsp_qseq>IGRGRFSVVRRCLQKGSPREVAAKFVSKK-LKRKEQ-VAHEAAVLRNLQ-------------------HPQLPSLLDTYETSSSFVLVLEL---------------------VAGYLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPS------------------AVRVKLVDLGEAVQITTHYY--VHVLLGSPEFASPEVVRGQPVALST--------------DAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVS-EEARSFVRLLLQGDYARRPPCSACLLDPWLQ</Hsp_qseq>
      <Hsp_hseq>LGDGNFSVVKECMNIHTKDLYAMKLIKKQTVKNKIQLIQREFDLLRSISEKIRDMEKKNEHSLDIFEGHHHILQLFDYFETADNIVLITQLCQKGDLYEKIVENQCLDLETQVTSYCACLVSVLEFLHSQGIVHRDLKAENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLVLADFGLAAEYNTSKVNSLKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGCPVDIWALGVLTYFMAFGYTPFDCTTDDETLECISKCDYYVDEQMMHDPKYEQFWNFVQCCFTIDPAVRRSAKNLKQHPFIK</Hsp_hseq>
      <Hsp_midline>+G G FSVV+ C+   +    A K + K+ +K K Q +  E  +LR++                    H  +  L D +ET+ + VL+ +L                     V  Y    +  L++LH+  I H D+K EN+L  +                      A  + L D G A +  T     +   +G+  + +PE+V+ + V   T              D W+LGVL Y +  G +PF   + DET   I + DY   E+       E+  +FV+     D A R         P+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>1.45972e-10</Hsp_evalue>
      <Hsp_query-from>6574</Hsp_query-from>
      <Hsp_query-to>7116</Hsp_query-to>
      <Hsp_hit-from>366</Hsp_hit-from>
      <Hsp_hit-to>570</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>209</Hsp_align-len>
      <Hsp_qseq>DSTYAELAEIGRGRFSVVRRCLQKGSPREVAAKFVSKKLKRKEQVAHEAAVLRNLQHPQLPS-------LLDTYETSSSFVLVLELVAGYLRDTLHALQY---------------------LHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPF</Hsp_qseq>
      <Hsp_hseq>NRKYLVLDILGQGTFGQVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKNHLCLVFELLSNNLYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILL--CAPDKPELKIIDFGSSCEEARTVYTYI--QSRFYRAPEIILGIPYSTSIDMWSLGCIVAELFLGIPIF</Hsp_hseq>
      <Hsp_midline>+  Y  L  +G+G F  V +C    +   +A K V  + +   Q   EA +L  L     P+       + D++   +   LV EL++  L + L   ++                     L   ++ H D+KPEN+L+   +P    +K++D G + +     Y ++   S  + +PE++ G P + S D WSLG +   L  G+  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>1.53293e-10</Hsp_evalue>
      <Hsp_query-from>6601</Hsp_query-from>
      <Hsp_query-to>7293</Hsp_query-to>
      <Hsp_hit-from>31</Hsp_hit-from>
      <Hsp_hit-to>273</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>253</Hsp_align-len>
      <Hsp_qseq>IGRGRFSVVRRCLQKGSPREVAAK-FVSKKLKRKEQVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAG---------------------YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWLQ</Hsp_qseq>
      <Hsp_hseq>IGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNT----VKLADFGVSTIVNSS--ALTLAGTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNPPYHNLT-DANIYYAVENDTYYPP---SSFSEPLKDFLSKCFVKNMYKRPTADQLLKHVWIN</Hsp_hseq>
      <Hsp_midline>IGRG + VV + + K + + VA K  V +  +    +  E ++L+NL H  +         S    ++LE  A                      Y+  TL  L+YLH   + H DIK  N+L+   +     VKL D G +  + +      L G+  + +PE++  +  +  +D WSLG     +L+   P+ + + D         D  +P    +S SE  + F+      +  +RP     L   W+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>2.3894e-10</Hsp_evalue>
      <Hsp_query-from>6691</Hsp_query-from>
      <Hsp_query-to>7254</Hsp_query-to>
      <Hsp_hit-from>194</Hsp_hit-from>
      <Hsp_hit-to>406</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>218</Hsp_align-len>
      <Hsp_qseq>KRKEQVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAG--------------------YLRDTLHALQYLHNCRIAHLDIKPENLLVEVS----------SPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARR</Hsp_qseq>
      <Hsp_hseq>KRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSI---IGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTG-SNHKVIINKIQQNKQGPKIPFY-LSEGMKDILNALLKKETAKR</Hsp_hseq>
      <Hsp_midline>KR E+   E ++L  ++HP +  L  ++  +S   L+L+ + G                    Y  +   AL++LH   + + D+KPEN L+             S  +     VD  +   +   Y +   +G+PE+ +PE++ G+  + + D +SLG L Y +L G  P+   S  +  +N  + +   P+  F  +SE  +  +  LL+ + A+R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>2.55013e-10</Hsp_evalue>
      <Hsp_query-from>6652</Hsp_query-from>
      <Hsp_query-to>7293</Hsp_query-to>
      <Hsp_hit-from>74</Hsp_hit-from>
      <Hsp_hit-to>314</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>245</Hsp_align-len>
      <Hsp_qseq>PREVAAKFV-----SKKLKRKEQVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAG-----YLRDT---------------LHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQI-TTHYYVHVLLGSPEFASPE-VVRGQPV-ALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRL-DY--SFPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWLQ</Hsp_qseq>
      <Hsp_hseq>PKQVAIKLIKRDSISNDYRKEVKIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNE----NLVITDFGFVNEFCSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGRLYNYINSTPLKFPDYILPIPRDLLRRMLVSDPKKRINLKQIKKHEWLK</Hsp_hseq>
      <Hsp_midline>P++VA K +     S   +++ ++  E   L++L HP +  L +  + S    +VLE   G     Y++                 +  + Y+H+  + H D+K ENLL++ +      + + D G   +  + +  +    GSP +A+PE V+  +P  A   D WS GV+ Y +L+G  P+ D+  +    +I RL +Y  S P ++   +    R  +R +L  D  +R          WL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>1.01033e-09</Hsp_evalue>
      <Hsp_query-from>6601</Hsp_query-from>
      <Hsp_query-to>7257</Hsp_query-to>
      <Hsp_hit-from>24</Hsp_hit-from>
      <Hsp_hit-to>261</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>245</Hsp_align-len>
      <Hsp_qseq>IGRGRFSVVRRCLQKGSPREVAAKFVSKKLKRK--EQVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAG----------------------YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRGQPVALS--TDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFASVSEEARSFVRLLLQGDYARRP</Hsp_qseq>
      <Hsp_hseq>IGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEG----MVKLGDFGVSGHIRSTLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPPLSKYDPMKVMTNLPKRK---PPKLQGPFSDAAKDFVAGCLVKTPADRP</Hsp_hseq>
      <Hsp_midline>IGRG F  V + + + +   VA K V+ +   +  E +A E   L  L+ P + + + T     S  +V+E   G                       + +    L+YLH  R  H DIK  N+L+         VKL D G +  I +       +G+P + +PEVV  +    +   D WSLG+  Y LL G+ P       +   N+ +     P +     S+ A+ FV   L    A RP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>1.14545e-09</Hsp_evalue>
      <Hsp_query-from>6601</Hsp_query-from>
      <Hsp_query-to>7122</Hsp_query-to>
      <Hsp_hit-from>29</Hsp_hit-from>
      <Hsp_hit-to>222</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>198</Hsp_align-len>
      <Hsp_qseq>IGRGRFSVVRRCLQKGSPREVAAKFVS--KKLKRKEQVAHEAAVLRNLQH-PQLPSLLDTYETSSSFVLVLELVAG-------------------YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQIT-THYYVHVLLGSPEFASPEVV-RGQPVALSTDAWSLGVLAYVLLSGVSPFLD</Hsp_qseq>
      <Hsp_hseq>IGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLRPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLIT----NEGNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYCD</Hsp_hseq>
      <Hsp_midline>IGRG+F VV +     + R  A K ++        E V  E   L +L+    +     +Y   +S  +++E  AG                    +R+ L AL+ +H   + H DIK  N+L+     +   VKL D G A Q+  T      + G+P + +PEV+  G       D WSLG+  Y + +G  P+ D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>6.50746e-09</Hsp_evalue>
      <Hsp_query-from>6577</Hsp_query-from>
      <Hsp_query-to>7176</Hsp_query-to>
      <Hsp_hit-from>48</Hsp_hit-from>
      <Hsp_hit-to>296</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>57</Hsp_gaps>
      <Hsp_align-len>253</Hsp_align-len>
      <Hsp_qseq>STYAELAEIGRGRFSVVRRCLQKGSPREVAAKFVSKKLKR----------KEQVAHEAAVLRNLQHPQLPSLLDTYET--SSSFVLVLELVA----------------------------GYLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITT------HYYVHVL----LGSPEFASPEVVRGQP---VALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFP</Hsp_qseq>
      <Hsp_hseq>NNFEILATLGNGQYGKVKLARDLGTGALVAIKILNRFEKRSGYSLQLKVENPRVNQEIEVMKRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLIS----SNGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPFNANSGLELFDSIINKPLEFP</Hsp_hseq>
      <Hsp_midline>+ +  LA +G G++  V+     G+   VA K +++  KR            +V  E  V++   H  +  L +      S+   LVLE  +                              + D +  L+YLH+  I H DIKP NLL+     S   VK+ D G A+   T        +  +L    LG+P F +PE+   +     + + D WSLGV  Y LL G  PF   S  E   +I      FP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.5362</Hsp_bit-score>
      <Hsp_score>140</Hsp_score>
      <Hsp_evalue>1.99341e-08</Hsp_evalue>
      <Hsp_query-from>6601</Hsp_query-from>
      <Hsp_query-to>7383</Hsp_query-to>
      <Hsp_hit-from>1181</Hsp_hit-from>
      <Hsp_hit-to>1467</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>118</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>295</Hsp_align-len>
      <Hsp_qseq>IGRGRFSVVRRCLQKGSPREVAAK------FVSKK---LKRKEQVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAG---------YLR-----------DTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVH--VLLGSPEFASPEVV-RGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYS--FPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWLQCPGYAYPGALLDVARLAAFIERRSHQNDAQ</Hsp_qseq>
      <Hsp_hseq>IGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDG----ICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANELLSHPFSEVNETFN----FKSTRLAKFIKSNDKLNSSK</Hsp_hseq>
      <Hsp_midline>IG+G F  V  CL   +   +A K      + S+    L   E +  E + L++L H  +   L     ++ + L LE VAG         Y R             L  L YLH+  I H D+K +NLL++         K+ D G + +    Y      + G+  + +PE+V   Q  +   D WSLG +   + +G  P+ +  V      I +   +   PE+    +S+  R+F+    + +  +RP  +  L  P+ +              RLA FI+     N ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>3.77463e-08</Hsp_evalue>
      <Hsp_query-from>6514</Hsp_query-from>
      <Hsp_query-to>7104</Hsp_query-to>
      <Hsp_hit-from>290</Hsp_hit-from>
      <Hsp_hit-to>525</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>240</Hsp_align-len>
      <Hsp_qseq>EELSADASSDGLRTVWKDN--FDSTYAELAEI-GRGRFSVVRRCLQKGSPREVAAK----FVSKKLKRK---------EQVAHEAAVLRNLQHPQLPSLLDTYETSSS-FVLVLELVAG--------------------YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLG--EAVQITTHYYVHVLLG----SPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSG</Hsp_qseq>
      <Hsp_hseq>DQKDSKNNTHNITTTKKDRQCFAEKYGRCQEVLGKGAFGVVRICQKKNVSSQDGNKSEKLYAVKEFKRRTSESAEKYSKRLTSEFCISSSLHHTNIVTTLDLFQDAKGEYCEVMEYCAGGDLFTLVVAAGKLEYMEADCFFKQLIRGVVYMHEMGVCHRDLKPENLLLTHDG----VLKITDFGNSECFKMAWEKNIHLSGGVCGSSPYIAPEEYIKEEFDPRPVDIWACGVIYMAMRTG</Hsp_hseq>
      <Hsp_midline>++  +  ++  + T  KD   F   Y    E+ G+G F VVR C +K    +   K    +  K+ KR+         +++  E  +  +L H  + + LD ++ +   +  V+E  AG                    + +  +  + Y+H   + H D+KPENLL+         +K+ D G  E  ++     +H+  G    SP  A  E ++ +      D W+ GV+   + +G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>4.2386e-08</Hsp_evalue>
      <Hsp_query-from>6577</Hsp_query-from>
      <Hsp_query-to>7155</Hsp_query-to>
      <Hsp_hit-from>5</Hsp_hit-from>
      <Hsp_hit-to>221</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>227</Hsp_align-len>
      <Hsp_qseq>STYAELAEIGRGRFSVVRRCLQKGSPREVAAKFVSKKLKRKE----QVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAGYLR-------------------------DTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEA----VQITTHYYVHVLLGSPEFASPEVVRG-QPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNIC</Hsp_qseq>
      <Hsp_hseq>SQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEV--KLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRG----QLKLGDFGLARAFGIPVNTFSSEVVTLW---YRAPDVLMGSRTYSTSIDIWSCGCILAEMITG-KPLFPGTNDEEQLKLI</Hsp_hseq>
      <Hsp_midline>S + +L ++G G ++ V + L K +   VA K V  KL  +E        E ++++ L+H  +  L D   T +   LV E +   L+                           L  L + H  +I H D+KP+NLL+        ++KL D G A    + + T     V L    + +P+V+ G +  + S D WS G +   +++G  P    + DE  L + </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YOR061W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:441534:442553:1 gene:YOR061W transcript:YOR061W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA2 description:Alpha&apos; catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000005587]</Hit_def>
  <Hit_accession>YOR061W</Hit_accession>
  <Hit_len>339</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>5.6487e-08</Hsp_evalue>
      <Hsp_query-from>6577</Hsp_query-from>
      <Hsp_query-to>7128</Hsp_query-to>
      <Hsp_hit-from>48</Hsp_hit-from>
      <Hsp_hit-to>247</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>209</Hsp_align-len>
      <Hsp_qseq>STYAELAEIGRGRFSVVR--RCLQKGSPREVAAKFVSKKLK--RKEQVAHEAAVLRNLQH-PQLPSLLDTYETSSSFV--LVLELVAG-----------------YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPE-VVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDES</Hsp_qseq>
      <Hsp_hseq>SNYEIINKIGRGKYSEVFSGRCIVNNQ------KCVIKVLKPVKMKKIYRELKILTNLTGGPNVVGLYDIVQDADSKIPALIFEEIKNVDFRTLYPTFKLPDIQYYFTQLLIALDYCHSMGIMHRDVKPQNVMID---PTERKLRLIDWGLAEFYHPGVDYNVRVASRYHKGPELLVNLNQYDYSLDLWSVGCMLAAIVFKKEPFFKGS</Hsp_hseq>
      <Hsp_midline>S Y  + +IGRG++S V   RC+          K V K LK  + +++  E  +L NL   P +  L D  + + S +  L+ E +                   Y    L AL Y H+  I H D+KP+N++++   P+  +++L+D G A         +V + S     PE +V       S D WS+G +   ++    PF   S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>9.58102e-08</Hsp_evalue>
      <Hsp_query-from>6589</Hsp_query-from>
      <Hsp_query-to>7179</Hsp_query-to>
      <Hsp_hit-from>43</Hsp_hit-from>
      <Hsp_hit-to>270</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>231</Hsp_align-len>
      <Hsp_qseq>ELAEIGRGRFSVVRRCLQKGSPREVAAKFVSKKLKRKEQV-AHEAAVLRNLQHPQLPSLLDTYETSSSFV---------LVLELVAGYLRDTLH-----------------------ALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPE-VVRGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPE</Hsp_qseq>
      <Hsp_hseq>EGKRIGHGSFGTVTQSILSSNSIEWLGPYAIKRVVKSPKVQSLELEILQNIRHPNLVTLEFFFESHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILI---IPSSGIAKVCDFGSAQRLDDNTELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPLFKGDSANSQLEEIAKLLGRFPK</Hsp_hseq>
      <Hsp_midline>E   IG G F  V + +   +  E    +  K++ +  +V + E  +L+N++HP L +L   +E+  +            V+E +   L   +H                       AL  LH+  I H D+KP N+L+    PS+   K+ D G A ++  +  +     S  + +PE ++  +      D WSLG +   ++ G   F  +S +     I +L   FP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>1.23631e-07</Hsp_evalue>
      <Hsp_query-from>6583</Hsp_query-from>
      <Hsp_query-to>7119</Hsp_query-to>
      <Hsp_hit-from>7</Hsp_hit-from>
      <Hsp_hit-to>205</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>204</Hsp_align-len>
      <Hsp_qseq>YAELAEIGRGRFSVVRRCLQKGSPREVAAKFVSK---KLKRKEQVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLEL--------------------VAGYLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQI-TTHYYVHVLLGSPEFASPEVVRG-QPVALSTDAWSLGVLAYVLLSGVSPFL</Hsp_qseq>
      <Hsp_hseq>YTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNVIELIDIFMAYDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLF---SPDG-QIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRI-PYL</Hsp_hseq>
      <Hsp_midline>Y +  ++G G ++VV    Q  + R++A K +     K         E   L+ +QHP +  L+D +    +  LVLE                     +  ++  TL  + + H   I H D+KP NLL    SP   ++K+ D G A  I   H  +   + +  + +PE++ G +    + D WS+GV+   L+  + P+L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>2.08054e-07</Hsp_evalue>
      <Hsp_query-from>6592</Hsp_query-from>
      <Hsp_query-to>7290</Hsp_query-to>
      <Hsp_hit-from>363</Hsp_hit-from>
      <Hsp_hit-to>623</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>267</Hsp_align-len>
      <Hsp_qseq>LAEIGRGRFSVVRRCLQKGSPREVAAKFVSKKLKRKE--QVAHEAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAGYLRDTL-----------------------HALQYL---HNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRG-----QPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRL-DYSFPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWL</Hsp_qseq>
      <Hsp_hseq>LDELGHGNYGNVSKVLHKPTNVIMATKEVRLELDEAKFRQILMELEVLHKCNSPYIVDFYGAFFIEGAVYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHN--IIHRDVKPTNILCSANQGT---VKLCDFGVSGNLVASL-AKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYPPETYDNIFSQLSAIVDGPPPRLPSDKFSSDAQDFVSLCLQKIPERRPTYAALTEHPWL</Hsp_hseq>
      <Hsp_midline>L E+G G +  V + L K +   +A K V  +L   +  Q+  E  VL     P +      +    +  + +E + G   D +                       H L+ L   HN  I H D+KP N+L   +  +   VKL D G +  +         +G   + +PE ++          + +D WSLG+    +  G  P+  E+ D     +  + D   P       S +A+ FV L LQ    RRP  +A    PWL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>2.55958e-07</Hsp_evalue>
      <Hsp_query-from>6808</Hsp_query-from>
      <Hsp_query-to>7116</Hsp_query-to>
      <Hsp_hit-from>330</Hsp_hit-from>
      <Hsp_hit-to>445</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>116</Hsp_align-len>
      <Hsp_qseq>LVAGYLRDTLHALQYLHNCRIAHLDIKPENLLVEVS---------SPSAVR---VKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRGQPV-ALSTDAWSLGVLAYVLLSGVSPF</Hsp_qseq>
      <Hsp_hseq>LIQRIFTEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLCKKIENNEMCTARCGSEDYVSPEILMGVPYDGHLSDTWALGVILYSLFEDRLPF</Hsp_hseq>
      <Hsp_midline>L+     + + A++YLH   I H D+K EN+L++ S         SP   +   ++L D G   +I  +       GS ++ SPE++ G P     +D W+LGV+ Y L     PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>6.0775e-07</Hsp_evalue>
      <Hsp_query-from>6601</Hsp_query-from>
      <Hsp_query-to>7290</Hsp_query-to>
      <Hsp_hit-from>1272</Hsp_hit-from>
      <Hsp_hit-to>1558</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>69</Hsp_gaps>
      <Hsp_align-len>293</Hsp_align-len>
      <Hsp_qseq>IGRGRFSVVRRCLQKGSPREVAAKFVSKKLKRKEQ-----VAHEAAVLRNLQHPQLPS------------LLDTYETSSSFVLVLE--------LVAGYLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTH------------------YYVHV---------------LLGSPEFASPEVVRGQPVA---LSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYS--FPEEYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWL</Hsp_qseq>
      <Hsp_hseq>IGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAALLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGV----IKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPWANLDNEWAIMYHVAAGHTPQFPTK--DEVSSAGMKFLERCLIQNPSKRASAVELLMDPWI</Hsp_hseq>
      <Hsp_midline>IG G F  V   +   +   +A K ++ +  +  Q     +  E +VL  L HP + S            +   Y    S   +LE        +   Y    L  L YLH   I H D+KPEN+L++ +      +K VD G A +I  +                     HV               ++G+P + +PE + G        + D WSLG +   +++G  P+ +   +   +      ++  FP +    VS     F+   L  + ++R      L+DPW+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>6.93658e-07</Hsp_evalue>
      <Hsp_query-from>6577</Hsp_query-from>
      <Hsp_query-to>7125</Hsp_query-to>
      <Hsp_hit-from>131</Hsp_hit-from>
      <Hsp_hit-to>382</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>77</Hsp_gaps>
      <Hsp_align-len>256</Hsp_align-len>
      <Hsp_qseq>STYAELAEIGRGRFSVVRRCLQKGSPREVAAKFV---------------SKKLKRKEQVAHEAAVLRNLQHPQLPSLLDTYE--TSSSFVLVLELVA----------------------------GYLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHV-----------LLGSPEFASPEV-----------------VRGQPVALSTDAWSLGVLAYVLLSGVSPFLDE</Hsp_qseq>
      <Hsp_hseq>NTYEIIKELGHGQHGKVKLARDILSKQLVAIKIVDRHEKKQRKFFTFIKSSKISENDKIKREIAIMKKCHHKHVVQLIEVLDDLKSRKIYLVLEYCSRGEVKWCPPDCMESDAKGPSLLSFQETREILRGVVLGLEYLHYQGIIHRDIKPANLLISGDGT----VKISDFGVSLAASSTNSSDSSESLDELELAKTVGTPAFFAPEMCLGEDAFTRYNLTKENLFRGSCISFMIDIWAVGVTLYCLLFGMLPFFSD</Hsp_hseq>
      <Hsp_midline>+TY  + E+G G+   V+      S + VA K V               S K+   +++  E A+++   H  +  L++  +   S    LVLE  +                              LR  +  L+YLH   I H DIKP NLL+         VK+ D G ++  ++                  +G+P F +PE+                  RG  ++   D W++GV  Y LL G+ PF  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>9.28373e-07</Hsp_evalue>
      <Hsp_query-from>6601</Hsp_query-from>
      <Hsp_query-to>6954</Hsp_query-to>
      <Hsp_hit-from>358</Hsp_hit-from>
      <Hsp_hit-to>495</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>IGRGRFSVVRRCLQKGSPREVAAKFVSK-KLKRKEQVAH---EAAVLRNLQHPQLPSLLDTYETSSSFVLVLELVAG--------------------YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLG</Hsp_qseq>
      <Hsp_hseq>IGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIRG----HIKLSDFG</Hsp_hseq>
      <Hsp_midline>IG+G F  VR   +K + +  A K + K ++ +K+Q+AH   E  VL     P + SL  +++ +    L++E + G                    Y+ + + A++ +H     H DIKP+N+L+++       +KL D G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>1.09196e-06</Hsp_evalue>
      <Hsp_query-from>6835</Hsp_query-from>
      <Hsp_query-to>7116</Hsp_query-to>
      <Hsp_hit-from>315</Hsp_hit-from>
      <Hsp_hit-to>404</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>95</Hsp_align-len>
      <Hsp_qseq>LHALQYLH-NCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRGQPVALSTDAWSLGVLAYVLLSGVSPF</Hsp_qseq>
      <Hsp_hseq>LNGLDHLYRQYKIIHRDIKPSNVLIN----SKGQIKLCDFGVSKKLI-NSIADTFVGTSTYMSPERIQGNVYSIKGDVWSLGLMIIELVTGEFPL</Hsp_hseq>
      <Hsp_midline>L+ L +L+   +I H DIKP N+L+     S  ++KL D G + ++  +      +G+  + SPE ++G   ++  D WSLG++   L++G  P </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>1.26836e-06</Hsp_evalue>
      <Hsp_query-from>6601</Hsp_query-from>
      <Hsp_query-to>7290</Hsp_query-to>
      <Hsp_hit-from>45</Hsp_hit-from>
      <Hsp_hit-to>322</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>60</Hsp_gaps>
      <Hsp_align-len>284</Hsp_align-len>
      <Hsp_qseq>IGRGRFSVVRRCLQKGSPREVAAKFVSKKLKRKEQVAHEAAVLRNLQHPQLPSL-LDTYETSSSFVLVLELVAGYLRDTLH---------------------------ALQYLHN-CRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRG-QPVALSTDAWSLGVLAYVLLSGVSPF-----LDESVD-----------ETC-LNICRLDYSFPE-------EYFASVSEEARSFVRLLLQGDYARRPPCSACLLDPWL</Hsp_qseq>
      <Hsp_hseq>VGHGSFGVVFATVIQETNEKVAIK---KVLQDKRFKNRELEIMKMLSHINIIDLKYFFYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVD---PETWSLKLCDFGSAKQLKPTEPNVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILGTPSKQEICSMNPNYMEHKFPQIKPIPLSRVFKKEDDQTVEFLADVLKYDPLERFNALQCLCSPYF</Hsp_hseq>
      <Hsp_midline>+G G F VV   + + +  +VA K   K L+ K     E  +++ L H  +  L    YE  S   + L L+  Y+  +L+                           +L YLH+   + H DIKP+NLLV+   P    +KL D G A Q+         + S  + +PE++ G        D WS G +   LL G   F     +D+ V+           E C +N   +++ FP+         F    ++   F+  +L+ D   R     CL  P+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>1.41598e-06</Hsp_evalue>
      <Hsp_query-from>6820</Hsp_query-from>
      <Hsp_query-to>7290</Hsp_query-to>
      <Hsp_hit-from>1138</Hsp_hit-from>
      <Hsp_hit-to>1310</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>189</Hsp_align-len>
      <Hsp_qseq>YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHV-----------------LLGSPEFASPEVVRGQPVA---LSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFAS------------VSEEARSFVRLLLQGDYARRPPCSACLLDPWL</Hsp_qseq>
      <Hsp_hseq>YTFELLEGLAYLHQSGVVHRDIKPENILLDFNGI----IKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPW------------SNLDNEWAIMYHVAAGRIPQLPNRDEMTAAGRAFLERCLVQDPTMRATAVELLIDPWM</Hsp_hseq>
      <Hsp_midline>Y  + L  L YLH   + H DIKPEN+L++ +      +K VD G A  +       V                 ++G+P + +PE + G  V     + D W+LG +   + +G  P+              LD  +   Y  +            ++   R+F+   L  D   R      L+DPW+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YBR059C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:356861:360187:-1 gene:YBR059C transcript:YBR059C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AKL1 description:Ser-Thr protein kinase; member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization [Source:SGD;Acc:S000000263]</Hit_def>
  <Hit_accession>YBR059C</Hit_accession>
  <Hit_len>1108</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>1.60029e-06</Hsp_evalue>
      <Hsp_query-from>6757</Hsp_query-from>
      <Hsp_query-to>7194</Hsp_query-to>
      <Hsp_hit-from>138</Hsp_hit-from>
      <Hsp_hit-to>290</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>164</Hsp_align-len>
      <Hsp_qseq>SLLDTYETSSSFVLVLELVAGYLRDTLHALQYLHNCRIA--HLDIKPENLLVEVSSPSAVRVKLVDLGEAVQ----ITTHY---------YVHVLLGSPEFASPEVV---RGQPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRLDYSFPEEYFAS</Hsp_qseq>
      <Hsp_hseq>SLLDYMNQRLSTKLTEAEIVKIMYDVALSISQMHYLPVSLIHRDIKIENVLVDAKN----NFKLADFGSTSTCFPIVTTHQDIALLTQNIYVHT---TPQYRSPEMIDLYRCLPINEKSDIWALGVFLYKLLFFTTPF--EMTGQFA--ILHSKYEFPVNKYSS</Hsp_hseq>
      <Hsp_midline>SLLD      S  L    +   + D   ++  +H   ++  H DIK EN+LV+  +      KL D G        +TTH          YVH    +P++ SPE++   R  P+   +D W+LGV  Y LL   +PF  E   +    I    Y FP   ++S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YDL079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:312951:314748:-1 gene:YDL079C transcript:YDL079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRK1 description:Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication [Source:SGD;Acc:S000002237]</Hit_def>
  <Hit_accession>YDL079C</Hit_accession>
  <Hit_len>501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>1.63017e-06</Hsp_evalue>
      <Hsp_query-from>6529</Hsp_query-from>
      <Hsp_query-to>7161</Hsp_query-to>
      <Hsp_hit-from>146</Hsp_hit-from>
      <Hsp_hit-to>380</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>241</Hsp_align-len>
      <Hsp_qseq>DASSDGLRTVWKDNFDSTYAELAEIGRGRFSVVRRCLQKGSPREVAAKFVSKKLKRKEQVAHEAAVLRNLQHPQLPSL-LDTYETSSSFVLVLELVAGYLRDTLH---------------------------ALQYLHNC-RIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHVLLGSPEFASPEVVRG-QPVALSTDAWSLGVLAYVLLSGVSPFLDESVDETCLNICRL</Hsp_qseq>
      <Hsp_hseq>DRKTDVDRKNHGGTIDISYPTTEVVGHGSFGVVVTTVIIETNQKVAIKKVLQDRRYKNR---ELETMKMLCHPNTVGLQYYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNVPRICHRDIKPQNLLVD---PTTFSFKICDFGSAKCLKPDQPNVSYICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKI</Hsp_hseq>
      <Hsp_midline>D  +D  R       D +Y     +G G F VV   +   + ++VA K V +  + K +   E   ++ L HP    L    YE      + L LV  Y+  +L+                           AL YLHN  RI H DIKP+NLLV+   P+    K+ D G A  +         + S  + +PE++ G    +   D WS   +   LL G   F  ES  +  + I ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YKL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:347214:349136:-1 gene:YKL048C transcript:YKL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ELM1 description:Serine/threonine protein kinase; regulates the orientation checkpoint, the morphogenesis checkpoint and the metabolic switch from fermentative to oxidative metabolism by phosphorylating the activation loop of Kin4p, Hsl1p and Snf4p respectively; cooperates with Hsl7p in recruiting Hsl1p to the septin ring, a prerequisite for subsequent recruitment, phosphorylation, and degradation of Swe1p; forms part of the bud neck ring; regulates cytokinesis [Source:SGD;Acc:S000001531]</Hit_def>
  <Hit_accession>YKL048C</Hit_accession>
  <Hit_len>640</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>6.93127e-06</Hsp_evalue>
      <Hsp_query-from>6823</Hsp_query-from>
      <Hsp_query-to>7140</Hsp_query-to>
      <Hsp_hit-from>240</Hsp_hit-from>
      <Hsp_hit-to>362</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>53</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>126</Hsp_align-len>
      <Hsp_qseq>LRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAV-------------QITTHYYVHVLLGSPEFASPEVVR-GQPV------ALSTDAWSLGVLAYVLLSGVSPFLDESVDET</Hsp_qseq>
      <Hsp_hseq>LEDMTKGLEYLHSQGCIHRDIKPSNILLDEEEKVA---KLSDFGSCIFTPQSLPFSDANFEDCFQRELNKIVGTPAFIAPELCHLGNSKRDFVTDGFKLDIWSLGVTLYCLLYNELPFFGENEFET</Hsp_hseq>
      <Hsp_midline>L D    L+YLH+    H DIKP N+L++     A   KL D G  +             +      ++ ++G+P F +PE+   G             D WSLGV  Y LL    PF  E+  ET</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YJL165C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:106894:109461:-1 gene:YJL165C transcript:YJL165C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HAL5 description:Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters; HAL5 has a paralog, KKQ8, that arose from the whole genome duplication [Source:SGD;Acc:S000003701]</Hit_def>
  <Hit_accession>YJL165C</Hit_accession>
  <Hit_len>855</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>7.18983e-06</Hsp_evalue>
      <Hsp_query-from>6820</Hsp_query-from>
      <Hsp_query-to>7104</Hsp_query-to>
      <Hsp_hit-from>668</Hsp_hit-from>
      <Hsp_hit-to>765</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>102</Hsp_align-len>
      <Hsp_qseq>YLRDTLHALQYLHNCRIAHLDIKPENLLVEVSSPSAVRVKLVDLGEAVQITTHYYVHV-----LLGSPEFASPE--VVRGQPVALSTDAWSLGVLAYVLLSG</Hsp_qseq>
      <Hsp_hseq>FMKQLLNGVQYMHDHGIAHCDLKPENILFQ---PNGL-LKICDFGTSSVFQTAWEKHVHFQSGAMGSEPYVAPEEFIRDAEYDPRLVDCWSCGIVYCTMVMG</Hsp_hseq>
      <Hsp_midline>+++  L+ +QY+H+  IAH D+KPEN+L +   P+ + +K+ D G +    T +  HV      +GS  + +PE  +   +      D WS G++   ++ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>108</Statistics_hsp-len>
      <Statistics_eff-space>6599398466</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052100-RA transcript Note:&quot;Similar to CROT Peroxisomal carnitine O-octanoyltransferase (Bos taurus)&quot; offset:465 AED:0.24 eAED:0.24 QI:465|0.57|0.6|0.93|0.92|0.86|15|507|470</Iteration_query-def>
  <Iteration_query-len>2385</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YML042W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:192788:194800:1 gene:YML042W transcript:YML042W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CAT2 description:Carnitine acetyl-CoA transferase; present in both mitochondria and peroxisomes; transfers activated acetyl groups to carnitine to form acetylcarnitine which can be shuttled across membranes [Source:SGD;Acc:S000004506]</Hit_def>
  <Hit_accession>YML042W</Hit_accession>
  <Hit_len>670</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>89.7373</Hsp_bit-score>
      <Hsp_score>221</Hsp_score>
      <Hsp_evalue>5.51735e-19</Hsp_evalue>
      <Hsp_query-from>505</Hsp_query-from>
      <Hsp_query-to>1632</Hsp_query-to>
      <Hsp_hit-from>67</Hsp_hit-from>
      <Hsp_hit-to>489</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>103</Hsp_identity>
      <Hsp_positive>174</Hsp_positive>
      <Hsp_gaps>55</Hsp_gaps>
      <Hsp_align-len>427</Hsp_align-len>
      <Hsp_qseq>TFEHQDSLPALPVPSLDETLTKYLDSVRPFATDEELAHTREVV-RRFKEGVGAKLHALLLRRGAVRQNWLEEWWLNKAYLESRGP-QQITGNFGGPGPYLEHVW-----PPKAGTQXXXXXXXXXXXXTHRA------KGVPLDMHQFRMIFAMA--------SEKRHLIDHEEELN----AEMHKFVRIFTFDSLAPGGDI-LTPPELQSQL-AVVKGRCAAEPEGPGLSVLTAGDRASWAK-HINAXXXXXXXXXXXQASPSA---------SPSDYSELQSWALAGNARGRWGDKSYNLIVFENGTCVSNCDHAPYDAMVLVSTTSYA---ENTLKRDDGV-----------WVPKELRFRLDERILSDIAHSEALYNRQAKDLQVVSLAFTAFGKLLIKQRGLHPDTYVQLALQLAYYRLHGR</Hsp_qseq>
      <Hsp_hseq>TFAKQQDLPSLPVPELKSTLDKYLQTIRPFCNDVETFERQQLLCKDFSEHMGPILQDRLKEYANDKRNWMAKFWDEQSYLQYNDPIVPYVSYFYSHMPLPNHLSKIDNDPLIKATAIISTVVKFIEAIKDESLPVEIIKGMPFCMNSFSLMFNTSRLPGKPEDNQDTNIFYSVYENNFVTIAYKGKFYKLMTHD----GNDKPLSENEIWRQLYSVVFQGSQSDPKLGGIGSLTSLPRDQWREVHLELMKDPISQDSLETIHKSSFMLCLDLDQSPVTLEEKSRNCWHGDGINRFYDKSLQFLVTGNGSSGFLAEHSKMDGTPTLFLNNYVCQQLNKLDVDDFMRKVITPSSTVAMKPMELPFIITPKIHKAIESAQLQFKETIGEHDLRVWHYNKYGKTFIKRHGMSPDAFIQQVIQLAVFKYLKR</Hsp_hseq>
      <Hsp_midline>TF  Q  LP+LPVP L  TL KYL ++RPF  D E    ++++ + F E +G  L   L      ++NW+ ++W  ++YL+   P       F    P   H+      P    T +    +         +      KG+P  M+ F ++F  +        ++  ++     E N    A   KF ++ T D    G D  L+  E+  QL +VV     ++P+  G+  LT+  R  W + H+  ++  +    LE    S+         SP    E       G+   R+ DKS   +V  NG+     +H+  D    +   +Y     N L  DD +             P EL F +  +I   I  ++  +     +  +    +  +GK  IK+ G+ PD ++Q  +QLA ++   R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1587159166</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

