<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0058259-RA transcript Note:&quot;Similar to Sperm acrosomal protein FSA-ACR.1 (Fragment) (Vulpes vulpes)&quot; offset:0 AED:0.28 eAED:0.28 QI:0|0|0|0.75|1|1|4|0|526</BlastOutput_query-def>
  <BlastOutput_query-len>1581</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058259-RA transcript Note:&quot;Similar to Sperm acrosomal protein FSA-ACR.1 (Fragment) (Vulpes vulpes)&quot; offset:0 AED:0.28 eAED:0.28 QI:0|0|0|0.75|1|1|4|0|526</Iteration_query-def>
  <Iteration_query-len>1581</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>993157811</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058262-RA transcript Note:&quot;Similar to S-antigen protein (Plasmodium falciparum (isolate v1))&quot; offset:0 AED:0.08 eAED:0.34 QI:0|0|0|0.5|1|1|2|0|227</Iteration_query-def>
  <Iteration_query-len>684</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>86</Statistics_hsp-len>
      <Statistics_eff-space>333198314</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0032624-RA transcript Note:&quot;Similar to IL6ST Interleukin-6 receptor subunit beta (Homo sapiens)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.45|0.41|12|106|515</Iteration_query-def>
  <Iteration_query-len>1654</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1042902552</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0009548-RA transcript Note:&quot;Protein of unknown function&quot; offset:1 AED:1.00 eAED:1.00 QI:1|0|0|0|0|0|6|2|395</Iteration_query-def>
  <Iteration_query-len>1188</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>92</Statistics_hsp-len>
      <Statistics_eff-space>701287568</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058268-RA transcript Note:&quot;Similar to MMACHC Methylmalonic aciduria and homocystinuria type C protein homolog (Gallus gallus)&quot; offset:0 AED:0.46 eAED:0.47 QI:0|0.33|0.46|0.92|1|1|13|0|400</Iteration_query-def>
  <Iteration_query-len>1203</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:859346:861520:1 gene:YDR205W transcript:YDR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MSC2 description:Endoplasmic reticulum zinc transporter; part of a heterodimeric transporter with Zrg17p that transfers zinc from the cytosol to the ER lumen; member of the cation diffusion facilitator family of efflux pumps; localizes to ER and nucleus; mutations affect the cellular distribution of zinc and also confer defects in meiotic recombination between homologous chromatids [Source:SGD;Acc:S000002613]</Hit_def>
  <Hit_accession>YDR205W</Hit_accession>
  <Hit_len>724</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>1.03636e-10</Hsp_evalue>
      <Hsp_query-from>679</Hsp_query-from>
      <Hsp_query-to>879</Hsp_query-to>
      <Hsp_hit-from>412</Hsp_hit-from>
      <Hsp_hit-to>478</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>42</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>67</Hsp_align-len>
      <Hsp_qseq>LGLISDSFHMFFDCTALLAGLAASVISRWHSNDAFSYGYVRAEVMAGFVNGLFLIFTAFFIFSEGIE</Hsp_qseq>
      <Hsp_hseq>LGLLSDSLHMALDCTSLLLGLIAGVLTKKPASDKFPFGLNYLGTLAGFTNGVLLLGIVCGIFVEAIE</Hsp_hseq>
      <Hsp_midline>LGL+SDS HM  DCT+LL GL A V+++  ++D F +G      +AGF NG+ L+     IF E IE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YMR243C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:754838:756166:-1 gene:YMR243C transcript:YMR243C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZRC1 description:Vacuolar membrane zinc transporter; transports zinc from cytosol to vacuole for storage; also has role in resistance to zinc shock resulting from sudden influx of zinc into cytoplasm; human ortholog SLC30A10 functions as a Mn transporter and mutations in SLC30A10 cause neurotoxic accumulation of Mn in liver and brain; ZRC1 has a paralog, COT1, that arose from the whole genome duplication [Source:SGD;Acc:S000004856]</Hit_def>
  <Hit_accession>YMR243C</Hit_accession>
  <Hit_len>442</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>6.93384e-08</Hsp_evalue>
      <Hsp_query-from>679</Hsp_query-from>
      <Hsp_query-to>879</Hsp_query-to>
      <Hsp_hit-from>33</Hsp_hit-from>
      <Hsp_hit-to>100</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>41</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>68</Hsp_align-len>
      <Hsp_qseq>LGLISDSFHMFFDCTALLAGLAASVISRWHSNDA-FSYGYVRAEVMAGFVNGLFLIFTAFFIFSEGIE</Hsp_qseq>
      <Hsp_hseq>LALIADSFHMLNDIISLLVALWAVDVAKNRGPDAKYTYGWKRAEILGALINAVFLIALCFSIMIEALQ</Hsp_hseq>
      <Hsp_midline>L LI+DSFHM  D  +LL  L A  +++    DA ++YG+ RAE++   +N +FLI   F I  E ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YOR316C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:906236:907555:-1 gene:YOR316C transcript:YOR316C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:COT1 description:Vacuolar transporter that mediates zinc transport into the vacuole; overexpression confers resistance to cobalt and rhodium; protein abundance increases in response to DNA replication stress; COT1 has a paralog, ZRC1, that arose from the whole genome duplication [Source:SGD;Acc:S000005843]</Hit_def>
  <Hit_accession>YOR316C</Hit_accession>
  <Hit_len>439</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>1.02425e-06</Hsp_evalue>
      <Hsp_query-from>679</Hsp_query-from>
      <Hsp_query-to>879</Hsp_query-to>
      <Hsp_hit-from>34</Hsp_hit-from>
      <Hsp_hit-to>101</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>39</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>68</Hsp_align-len>
      <Hsp_qseq>LGLISDSFHMFFDCTALLAGL-AASVISRWHSNDAFSYGYVRAEVMAGFVNGLFLIFTAFFIFSEGIE</Hsp_qseq>
      <Hsp_hseq>LALIADSFHMLNDIISLVVALWAVNVAKNRNPDSTYTYGWKRAEILGALINAVFLIALCVSILIEALQ</Hsp_hseq>
      <Hsp_midline>L LI+DSFHM  D  +L+  L A +V    + +  ++YG+ RAE++   +N +FLI     I  E ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>92</Statistics_hsp-len>
      <Statistics_eff-space>712821903</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0043845-RA transcript Note:&quot;Protein of unknown function&quot; offset:403 AED:1.00 eAED:1.00 QI:403|0|0|0|0|0.2|5|1|210</Iteration_query-def>
  <Iteration_query-len>1034</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YOR120W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:551114:552052:1 gene:YOR120W transcript:YOR120W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCY1 description:Glycerol dehydrogenase; involved in an alternative pathway for glycerol catabolism used under microaerobic conditions; also has mRNA binding activity; member of the aldo-keto reductase (AKR) family; human homolog AKR1B1 can complement yeast null mutant; protein abundance increases in response to DNA replication stress; GCY1 has a paralog, YPR1, that arose from the whole genome duplication [Source:SGD;Acc:S000005646]</Hit_def>
  <Hit_accession>YOR120W</Hit_accession>
  <Hit_len>312</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>1.04945e-08</Hsp_evalue>
      <Hsp_query-from>238</Hsp_query-from>
      <Hsp_query-to>387</Hsp_query-to>
      <Hsp_hit-from>35</Hsp_hit-from>
      <Hsp_hit-to>83</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>25</Hsp_identity>
      <Hsp_positive>37</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>50</Hsp_align-len>
      <Hsp_qseq>SHAAVLYALGACGVRHVDTARRYGCEERVGAALRESGVPRASVWLTSKLW</Hsp_qseq>
      <Hsp_hseq>AYKAVLTALKD-GYRHIDTAAIYRNEDQVGQAIKDSGVPREEIFVTTKLW</Hsp_hseq>
      <Hsp_midline>++ AVL AL   G RH+DTA  Y  E++VG A+++SGVPR  +++T+KLW</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YDR368W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1213904:1214842:1 gene:YDR368W transcript:YDR368W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPR1 description:NADPH-dependent aldo-keto reductase; reduces multiple substrates including 2-methylbutyraldehyde and D,L-glyceraldehyde, expression is induced by osmotic and oxidative stress; functionally redundant with other aldo-keto reductases; protein abundance increases in response to DNA replication stress; YPR1 has a paralog, GCY1, that arose from the whole genome duplication; human homolog AKR1B1 can complement yeast null mutant [Source:SGD;Acc:S000002776]</Hit_def>
  <Hit_accession>YDR368W</Hit_accession>
  <Hit_len>312</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>6.25247e-08</Hsp_evalue>
      <Hsp_query-from>247</Hsp_query-from>
      <Hsp_query-to>387</Hsp_query-to>
      <Hsp_hit-from>38</Hsp_hit-from>
      <Hsp_hit-to>83</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>34</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>47</Hsp_align-len>
      <Hsp_qseq>AVLYALGACGVRHVDTARRYGCEERVGAALRESGVPRASVWLTSKLW</Hsp_qseq>
      <Hsp_hseq>SVIAALKA-GYRHIDAAAIYLNEEEVGRAIKDSGVPREEIFITTKLW</Hsp_hseq>
      <Hsp_midline>+V+ AL A G RH+D A  Y  EE VG A+++SGVPR  +++T+KLW</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>589297018</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058270-RA transcript Note:&quot;Similar to ZK1290.5 Uncharacterized oxidoreductase ZK1290.5 (Caenorhabditis elegans)&quot; offset:0 AED:0.65 eAED:0.65 QI:0|0|0|0.33|1|1|3|0|96</Iteration_query-def>
  <Iteration_query-len>291</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YJR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:611195:612043:1 gene:YJR096W transcript:YJR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Xylose and arabinose reductase; member of the aldo-keto reductase (AKR) family; GFP-fusion protein is induced in response to the DNA-damaging agent MMS [Source:SGD;Acc:S000003857]</Hit_def>
  <Hit_accession>YJR096W</Hit_accession>
  <Hit_len>282</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>9.75651e-12</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>210</Hsp_query-to>
      <Hsp_hit-from>170</Hsp_hit-from>
      <Hsp_hit-to>238</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>25</Hsp_identity>
      <Hsp_positive>39</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>69</Hsp_align-len>
      <Hsp_qseq>KVEFHPYQQPRELMSFCRSRGIAFEGYCPLAKGQVLCDPTVQAVARKHARTPAQVCIRWSLQVFDFSLP</Hsp_qseq>
      <Hsp_hseq>QIEISPWIMRQELADYCKSKGLVVEAFAPLCHGYKMTNPDLLKVCKEVDRNPGQVLIRWSLQHGYLPLP</Hsp_hseq>
      <Hsp_midline>++E  P+   +EL  +C+S+G+  E + PL  G  + +P +  V ++  R P QV IRWSLQ     LP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YDR368W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1213904:1214842:1 gene:YDR368W transcript:YDR368W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPR1 description:NADPH-dependent aldo-keto reductase; reduces multiple substrates including 2-methylbutyraldehyde and D,L-glyceraldehyde, expression is induced by osmotic and oxidative stress; functionally redundant with other aldo-keto reductases; protein abundance increases in response to DNA replication stress; YPR1 has a paralog, GCY1, that arose from the whole genome duplication; human homolog AKR1B1 can complement yeast null mutant [Source:SGD;Acc:S000002776]</Hit_def>
  <Hit_accession>YDR368W</Hit_accession>
  <Hit_len>312</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>7.79518e-11</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>189</Hsp_query-to>
      <Hsp_hit-from>193</Hsp_hit-from>
      <Hsp_hit-to>256</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>37</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>64</Hsp_align-len>
      <Hsp_qseq>KVEFHPYQQPRELMSFCRSRGIAFEGYCPL--AKGQVLCDPTVQAVARKHARTPAQVCIRWSLQ</Hsp_qseq>
      <Hsp_hseq>QIEIHPLLPQDELIAFCKEKGIVVEAYSPFGSANAPLLKEQAIIDMAKKHGVEPAQLIISWSIQ</Hsp_hseq>
      <Hsp_midline>++E HP     EL++FC+ +GI  E Y P   A   +L +  +  +A+KH   PAQ+ I WS+Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YOR120W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:551114:552052:1 gene:YOR120W transcript:YOR120W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCY1 description:Glycerol dehydrogenase; involved in an alternative pathway for glycerol catabolism used under microaerobic conditions; also has mRNA binding activity; member of the aldo-keto reductase (AKR) family; human homolog AKR1B1 can complement yeast null mutant; protein abundance increases in response to DNA replication stress; GCY1 has a paralog, YPR1, that arose from the whole genome duplication [Source:SGD;Acc:S000005646]</Hit_def>
  <Hit_accession>YOR120W</Hit_accession>
  <Hit_len>312</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>8.77413e-11</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>270</Hsp_query-to>
      <Hsp_hit-from>193</Hsp_hit-from>
      <Hsp_hit-to>281</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>91</Hsp_align-len>
      <Hsp_qseq>KVEFHPYQQPRELMSFCRSRGIAFEGYCPLAK--GQVLCDPTVQAVARKHARTPAQVCIRWSLQVFDFSLPAEDMATLDGMHVGRKLIHLT</Hsp_qseq>
      <Hsp_hseq>QVEIHPLLPQDELINFCKSKGIVVEAYSPLGSTDAPLLKEPVILEIAKKNNVQPGHVVISWHVQRGYVVLPKS--VNPDRIKTNRKIFTLS</Hsp_hseq>
      <Hsp_midline>+VE HP     EL++FC+S+GI  E Y PL      +L +P +  +A+K+   P  V I W +Q     LP       D +   RK+  L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>68</Statistics_hsp-len>
      <Statistics_eff-space>71492743</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058271-RA transcript Note:&quot;Similar to s1pr1 Sphingosine 1-phosphate receptor 1 (Danio rerio)&quot; offset:0 AED:0.03 eAED:0.04 QI:0|-1|0|1|-1|1|1|0|449</Iteration_query-def>
  <Iteration_query-len>1350</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>93</Statistics_hsp-len>
      <Statistics_eff-space>821195319</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058272-RA transcript Note:&quot;Similar to Cdcp2 CUB domain-containing protein 2 (Mus musculus)&quot; offset:0 AED:0.35 eAED:0.38 QI:0|0|0|0.42|1|0.85|7|0|912</Iteration_query-def>
  <Iteration_query-len>2739</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>1840182938</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058273-RA transcript Note:&quot;Similar to tctex1d1-a Tctex1 domain-containing protein 1-A (Xenopus laevis)&quot; offset:0 AED:0.10 eAED:0.14 QI:0|0|0.66|1|0|0.33|3|3100|152</Iteration_query-def>
  <Iteration_query-len>3559</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2438501695</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058274-RA transcript Note:&quot;Similar to ACOT11 Acyl-coenzyme A thioesterase 11 (Homo sapiens)&quot; offset:0 AED:0.20 eAED:0.21 QI:0|0|0|1|1|1|13|0|437</Iteration_query-def>
  <Iteration_query-len>1314</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>93</Statistics_hsp-len>
      <Statistics_eff-space>793592115</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058275-RA transcript Note:&quot;Similar to Fam151a Protein FAM151A (Mus musculus)&quot; offset:146 AED:0.15 eAED:0.15 QI:146|0.57|0.62|1|0.85|0.87|8|1218|567</Iteration_query-def>
  <Iteration_query-len>3068</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>2086595641</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058277-RA transcript Note:&quot;Similar to TMEM59 Transmembrane protein 59 (Macaca fascicularis)&quot; offset:0 AED:0.10 eAED:0.10 QI:0|0.57|0.5|0.75|1|1|8|2720|338</Iteration_query-def>
  <Iteration_query-len>3737</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2571102248</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058279-RA transcript Note:&quot;Similar to HSPB11 Intraflagellar transport protein 25 homolog (Homo sapiens)&quot; offset:336 AED:0.44 eAED:0.46 QI:336|0.66|0.75|1|0|0|4|0|95</Iteration_query-def>
  <Iteration_query-len>624</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>85</Statistics_hsp-len>
      <Statistics_eff-space>289427241</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058264-RA transcript Note:&quot;Similar to Map3k1 Mitogen-activated protein kinase kinase kinase 1 (Mus musculus)&quot; offset:0 AED:0.18 eAED:0.28 QI:0|0|0|0.81|1|1|11|0|1045</Iteration_query-def>
  <Iteration_query-len>3138</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>117.472</Hsp_bit-score>
      <Hsp_score>293</Hsp_score>
      <Hsp_evalue>5.01183e-27</Hsp_evalue>
      <Hsp_query-from>2083</Hsp_query-from>
      <Hsp_query-to>2490</Hsp_query-to>
      <Hsp_hit-from>1170</Hsp_hit-from>
      <Hsp_hit-to>1306</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>140</Hsp_align-len>
      <Hsp_qseq>YQEGAEWLRGQQIGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDE----VVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIKA</Hsp_qseq>
      <Hsp_hseq>YKEFA-WMKGEMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPK--YSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKA</Hsp_hseq>
      <Hsp_midline>Y+E A W++G+ IG G+F + +   ++ TG +MAVKQV   +   S Q+E     V+ LR E+  +  LDH NI++ LG   + + Y+LF+E++AGGSV +L+  YG F E ++     Q+L+GLAYLHS  ++HRD+KA</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>1.57691e-13</Hsp_evalue>
      <Hsp_query-from>2722</Hsp_query-from>
      <Hsp_query-to>3120</Hsp_query-to>
      <Hsp_hit-from>1308</Hsp_hit-from>
      <Hsp_hit-to>1438</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>139</Hsp_align-len>
      <Hsp_qseq>NLLVDSMGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGLQ-YGRSCDIWSVGCVIIEMSCAKPPW-NAEKHSNHLALIFKIASXXXXXXXXXXLCPGL----RDVALRCLELQPSDRPVARDLLKHP</Hsp_qseq>
      <Hsp_hseq>NLLLDQDGI-CKISDFGISRK--SKDIYSNS-DMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEV----VAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANELLSHP</Hsp_hseq>
      <Hsp_midline>NLL+D  G   +I+DFG + +  SK   +      + GT+ +MAPE++   Q Y    DIWS+GC+++EM   K PW N E     +A +FKI  + +AP +P    P +    R+    C E+ P  RP A +LL HP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>106.301</Hsp_bit-score>
      <Hsp_score>264</Hsp_score>
      <Hsp_evalue>7.59212e-24</Hsp_evalue>
      <Hsp_query-from>2101</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>415</Hsp_hit-from>
      <Hsp_hit-to>581</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>167</Hsp_align-len>
      <Hsp_qseq>WLRGQQIGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNT-----------------------------------ASEQD---EVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>WLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIK</Hsp_hseq>
      <Hsp_midline>WL+G  IG G+F S +   +  TG LMAVKQV    N                                     + Q+   ++V  L+ E+ ++  L H NI+   GA+ E  N N+F+E++ GGSV+++LN YGPF E ++ ++  Q+L G+AYLH   +IHRDIK</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>5.43007e-12</Hsp_evalue>
      <Hsp_query-from>2719</Hsp_query-from>
      <Hsp_query-to>3132</Hsp_query-to>
      <Hsp_hit-from>583</Hsp_hit-from>
      <Hsp_hit-to>714</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>138</Hsp_align-len>
      <Hsp_qseq>ANLLVDSMGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGLQYGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKIASXXXXXXXXXXLCPGLRDVALRCLELQPSDRPVARDLLKHPVFRA</Hsp_qseq>
      <Hsp_hseq>ANILIDIKGC-VKITDFGISKKLSPLNKKQNK-RASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPF---PDFSQMQAIFKIGTNTTPEIPSWATSEG-KNFLRKAFELDYQYRPSALELLQHPWLDA</Hsp_hseq>
      <Hsp_midline>AN+L+D  G  ++I DFG + +L+       + +  L G++ +M+PEV++        DIWS GCV+IEM   K P+      + +  IFKI + TT          G ++   +  EL    RP A +LL+HP   A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>89.7373</Hsp_bit-score>
      <Hsp_score>221</Hsp_score>
      <Hsp_evalue>1.65037e-18</Hsp_evalue>
      <Hsp_query-from>2101</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>1266</Hsp_hit-from>
      <Hsp_hit-to>1392</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>129</Hsp_align-len>
      <Hsp_qseq>WLRGQQIGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>WQKRNFIGGGTFGRVYSAVDLDNGEILAVKEIN-IQDSKSMQ-KIFPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAALLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVK</Hsp_hseq>
      <Hsp_midline>W +   IG G F   + A D+  G ++AVK++  ++++ S Q ++   ++EE+ ++  L+HPNI+   G    +   N+F+E+  GGS+A LL       E V   Y  QLL GLAYLH + ++HRD+K</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>4.48967e-08</Hsp_evalue>
      <Hsp_query-from>2722</Hsp_query-from>
      <Hsp_query-to>3120</Hsp_query-to>
      <Hsp_hit-from>1395</Hsp_hit-from>
      <Hsp_hit-to>1556</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>166</Hsp_align-len>
      <Hsp_qseq>NLLVDSMGQRLRIADFGAAARLASKGT----------GAGEFQG------------------QLLGTIAFMAPEVLRG-LQYGR--SCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKIAS--XXXXXXXXXXLCPGLRDVALRCLELQPSDRPVARDLLKHP</Hsp_qseq>
      <Hsp_hseq>NILLDFNGV-IKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPW--ANLDNEWAIMYHVAAGHTPQFPTKDEVSSAGMKFLE-RCLIQNPSKRASAVELLMDP</Hsp_hseq>
      <Hsp_midline>N+L+D  G  ++  DFGAA ++A+ GT            GE +                    ++GT  +MAPE + G    G+  + D+WS+GCV++EM   + PW      N  A+++ +A+  T   PT       G++ +  RCL   PS R  A +LL  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.4261</Hsp_bit-score>
      <Hsp_score>215</Hsp_score>
      <Hsp_evalue>8.3457e-18</Hsp_evalue>
      <Hsp_query-from>2101</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>1034</Hsp_hit-from>
      <Hsp_hit-to>1160</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>129</Hsp_align-len>
      <Hsp_qseq>WLRGQQIGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>WQKRSFIGGGTFGQVYSAINLENGEILAVKEIK-IHDTTTMK-KIFPLIKEEMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEYCEGGSLASLLDHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIK</Hsp_hseq>
      <Hsp_midline>W +   IG G F   + A ++  G ++AVK++  + +T + + ++   ++EE+ ++  L+HPNI++  G    +   N+F+E+  GGS+A+LL+      E V   Y  +LL GLAYLH + ++HRDIK</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>1.04186e-06</Hsp_evalue>
      <Hsp_query-from>2722</Hsp_query-from>
      <Hsp_query-to>3120</Hsp_query-to>
      <Hsp_hit-from>1163</Hsp_hit-from>
      <Hsp_hit-to>1308</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>149</Hsp_align-len>
      <Hsp_qseq>NLLVDSMGQRLRIADFGAAARLASKGT------GAGEF------QGQLLGTIAFMAPEVLRGLQY-GR--SCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKIASXXX-XXXXXXXLCPGLRDVALRCLELQPSDRPVARDLLKHP</Hsp_qseq>
      <Hsp_hseq>NILLDFNGI-IKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPWS--NLDNEWAIMYHVAAGRIPQLPNRDEMTAAGRAFLERCLVQDPTMRATAVELLIDP</Hsp_hseq>
      <Hsp_midline>N+L+D  G  ++  DFG A  +    T         +F        +++GT  +MAPE + G    G+  + D+W++GCV++EM+  + PW+     N  A+++ +A+           +    R    RCL   P+ R  A +LL  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>1.33077e-13</Hsp_evalue>
      <Hsp_query-from>2092</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>79</Hsp_hit-from>
      <Hsp_hit-to>206</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>132</Hsp_align-len>
      <Hsp_qseq>GAEWLRGQQIGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>GKDYHRGHFLGEGGFARCFQIKD-DSGEIFAAKTVA---KASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLK</Hsp_hseq>
      <Hsp_midline>G ++ RG  +G G F+ CFQ +D  +G + A K V      + + ++  + L  EI++   + HPNI++ +    + SN  + +E    GS+  LL +     E  V  +  Q+   + Y+HS ++IHRD+K</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>8.36829e-08</Hsp_evalue>
      <Hsp_query-from>2722</Hsp_query-from>
      <Hsp_query-to>2955</Hsp_query-to>
      <Hsp_hit-from>209</Hsp_hit-from>
      <Hsp_hit-to>283</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>80</Hsp_align-len>
      <Hsp_qseq>NLLVDSMGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGLQYGRS--CDIWSVGCVIIEMSCAKPPWNA</Hsp_qseq>
      <Hsp_hseq>NIFFDS-NYNLKIGDFGLAAVLANES----ERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQA</Hsp_hseq>
      <Hsp_midline>N+  DS    L+I DFG AA LA++     E +  + GT  ++APEVL G   G S   DIWS+G ++  +   KPP+ A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>3.54634e-13</Hsp_evalue>
      <Hsp_query-from>2059</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>7</Hsp_hit-from>
      <Hsp_hit-to>154</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>148</Hsp_align-len>
      <Hsp_qseq>EHTRARQPYQEGAEWLRGQQIGLGAFSSCFQAQDIGTGTLMAVKQVT---YVRNTASEQDEVV--QTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>ETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLK</Hsp_hseq>
      <Hsp_midline>E   A +P      W  G+ +G G+      AQ   TG   AVK ++   +  N     D+ V    +  EI +M  L HPN++ +       +N  L +E+   G + NLL  +GP  ER  I+   Q++ G++Y H+  ++HRD+K</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>5.95057e-10</Hsp_evalue>
      <Hsp_query-from>2722</Hsp_query-from>
      <Hsp_query-to>3135</Hsp_query-to>
      <Hsp_hit-from>157</Hsp_hit-from>
      <Hsp_hit-to>288</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>139</Hsp_align-len>
      <Hsp_qseq>NLLVDSMGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGLQY-GRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKIASXXXXXXXXXXLCPGLRDVALRCLELQPSDRPVARDLLKHPVFRAW</Hsp_qseq>
      <Hsp_hseq>NLLLDSF-YNIKIADFGMAAL----QTDADLLETSC-GSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFD-EENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKY</Hsp_hseq>
      <Hsp_midline>NLL+DS    ++IADFG AA      T A   +    G+  + APE++ GL Y G + D+WS G ++  +   + P++ E++ N   L+ K+            +    +D+  + L + P  R   RD+L HP+ + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>3.99187e-13</Hsp_evalue>
      <Hsp_query-from>2086</Hsp_query-from>
      <Hsp_query-to>2490</Hsp_query-to>
      <Hsp_hit-from>20</Hsp_hit-from>
      <Hsp_hit-to>149</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>QEGAEWLRGQQIGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGP-FHERVVISYVEQLLRGLAYLHSNQLIHRDIKA</Hsp_qseq>
      <Hsp_hseq>EKSVQYHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVY------ENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKA</Hsp_hseq>
      <Hsp_midline>++  ++   Q IG G++   ++A +  T  ++A+K+V Y      E DE +  +  EI ++  L+H NI++  G   +     + +E+ A GS+  L+++      E    +YV Q L GL YLH   +IHRDIKA</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>6.2322e-08</Hsp_evalue>
      <Hsp_query-from>2719</Hsp_query-from>
      <Hsp_query-to>3117</Hsp_query-to>
      <Hsp_hit-from>150</Hsp_hit-from>
      <Hsp_hit-to>269</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>133</Hsp_align-len>
      <Hsp_qseq>ANLLVDSMGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGLQYGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKIASXXXXXXXXXXLCPGLRDVALRCLELQPSDRPVARDLLKH</Hsp_qseq>
      <Hsp_hseq>ANILL-SADNTVKLADFGVSTIVNSSALT-------LAGTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNPPYHNLTDAN-----IYYAVENDTYYPPSSFSEPLKDFLSKCFVKNMYKRPTADQLLKH</Hsp_hseq>
      <Hsp_midline>AN+L+ S    +++ADFG +  + S           L GT+ +MAPE+L         DIWS+G  ++EM    PP++    +N        A        P +    L+D   +C       RP A  LLKH</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.5514</Hsp_bit-score>
      <Hsp_score>166</Hsp_score>
      <Hsp_evalue>2.18516e-12</Hsp_evalue>
      <Hsp_query-from>2083</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>31</Hsp_hit-from>
      <Hsp_hit-to>163</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>135</Hsp_align-len>
      <Hsp_qseq>YQEGAEWLRGQQIGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>YVNKKKYVFGKTLGAGTFGVVRQAKNTETGEDVAVK--ILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLK</Hsp_hseq>
      <Hsp_midline>Y    +++ G+ +G G F    QA++  TG  +AVK    ++         ++ L +E+ ++ RL HPNI+        K  + +  +   GG + + + K G F E   +  + ++L  + Y+HS  ++HRD+K</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>1.43866e-09</Hsp_evalue>
      <Hsp_query-from>2713</Hsp_query-from>
      <Hsp_query-to>3120</Hsp_query-to>
      <Hsp_hit-from>164</Hsp_hit-from>
      <Hsp_hit-to>297</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>138</Hsp_align-len>
      <Hsp_qseq>PRANLLVDSMGQR-LRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGLQYGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHL-ALIFKIASXXXXXXXXXXLCPGLRDVALRCLELQPSDRPVARDLLKHP</Hsp_qseq>
      <Hsp_hseq>PENLLYIDKSDESPLVVADFGIAKRLKSDE----ELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAELLEDP</Hsp_hseq>
      <Hsp_midline>P   L +D   +  L +ADFG A RL S      E   +  G++ ++APEVL    +G+ CDIWS+G +   + C    + AE+  + L                  ++    +   L+ L L PS RP A +LL+ P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.5514</Hsp_bit-score>
      <Hsp_score>166</Hsp_score>
      <Hsp_evalue>3.92935e-12</Hsp_evalue>
      <Hsp_query-from>2752</Hsp_query-from>
      <Hsp_query-to>3090</Hsp_query-to>
      <Hsp_hit-from>207</Hsp_hit-from>
      <Hsp_hit-to>313</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>115</Hsp_align-len>
      <Hsp_qseq>LRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGLQYGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKI--ASXXXXXXXXXXLCPGLRDVALRCLELQPSDR</Hsp_qseq>
      <Hsp_hseq>LKIADFGFARFLP--NTSLAE---TLCGSPLYMAPEILNYQKYNAKADLWSVGTVVFEMCCGTPPFRA---SNHLELFKKIKRANDVITFPSYCNIEPELKELICSLLTFDPAQR</Hsp_hseq>
      <Hsp_midline>L+IADFG A  L    T   E    L G+  +MAPE+L   +Y    D+WSVG V+ EM C  PP+ A   SNHL L  KI  A+          + P L+++    L   P+ R</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>7.90341e-09</Hsp_evalue>
      <Hsp_query-from>2113</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>28</Hsp_hit-from>
      <Hsp_hit-to>174</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>150</Hsp_align-len>
      <Hsp_qseq>QQIGLGAFSSCFQAQDIGTGTL-MAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLN-----------------KYGP-------FHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>KEIGKGSFATVYRGHLTSDKSQHVAIKEVSRAK---LKNKKLLENLEIEIAILKKIKHPHIVGLIDCERTSTDFYLIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIK</Hsp_hseq>
      <Hsp_midline>++IG G+F++ ++       +  +A+K+V+  +    +  ++++ L  EI ++ ++ HP+I+ ++      +++ L +E+ A G +  LL                  KY P        H   V+SY++QL   L +L S  L+HRDIK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>1.00778e-11</Hsp_evalue>
      <Hsp_query-from>2101</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>19</Hsp_hit-from>
      <Hsp_hit-to>158</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>140</Hsp_align-len>
      <Hsp_qseq>WLRGQQIGLGAFSSCFQAQDIGTGTLMAVKQVTY-VRNT----------ASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>WKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLK</Hsp_hseq>
      <Hsp_midline>W  G+ +GLG+      A++  TG   AVK ++  V NT          ++  D +   +  EI +M  L+HPN++R+       ++  L +E+   G + NLL + GP  E   I +  Q++ G++Y H+  ++HRD+K</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>6.97674e-11</Hsp_evalue>
      <Hsp_query-from>2722</Hsp_query-from>
      <Hsp_query-to>3135</Hsp_query-to>
      <Hsp_hit-from>161</Hsp_hit-from>
      <Hsp_hit-to>292</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>143</Hsp_align-len>
      <Hsp_qseq>NLLVDSMGQRLRIADFGAAARLASKGTGAGEFQGQLL----GTIAFMAPEVLRGLQY-GRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKIASXXXXXXXXXXLCPGLRDVALRCLELQPSDRPVARDLLKHPVFRAW</Hsp_qseq>
      <Hsp_hseq>NLLLDH-KYNIKIADFGMAAL---------ETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFD-EEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERRIKTRDILKHPLLQKY</Hsp_hseq>
      <Hsp_midline>NLL+D     ++IADFG AA          E +G+LL    G+  + APE++ G+ Y G + D+WS G ++  +   + P++ E+  N   L+ K+            +    +D+  + L + P  R   RD+LKHP+ + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>1.56256e-11</Hsp_evalue>
      <Hsp_query-from>2164</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>125</Hsp_hit-from>
      <Hsp_hit-to>229</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>113</Hsp_align-len>
      <Hsp_qseq>GTGTLMAVKQVTYVRNTASEQDEVVQ-----TLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>STGYICALK--------VMEKEEIIKYNLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIK</Hsp_hseq>
      <Hsp_midline> TG + A+K          E++E+++       R E+ + + L+HPN+ +  G   ++    L +E++  G +  LL  +GPF++ +   Y+ Q+   L Y+H   +IHRDIK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>1.90092e-11</Hsp_evalue>
      <Hsp_query-from>2077</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>39</Hsp_hit-from>
      <Hsp_hit-to>173</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>137</Hsp_align-len>
      <Hsp_qseq>QPYQEGAEWLRGQQIGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>ESYVNRTNYIFGRTLGAGSFGVVRQARKLSTNEDVAIK--ILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLK</Hsp_hseq>
      <Hsp_midline>+ Y     ++ G+ +G G+F    QA+ + T   +A+K    ++      +  +Q L EE+ ++ +L HPNI+        K  + +  +   GG + + +   G F E   +  + Q+L  + Y+HS  ++HRD+K</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>1.72644e-10</Hsp_evalue>
      <Hsp_query-from>2713</Hsp_query-from>
      <Hsp_query-to>3120</Hsp_query-to>
      <Hsp_hit-from>174</Hsp_hit-from>
      <Hsp_hit-to>307</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>145</Hsp_align-len>
      <Hsp_qseq>PRANLLVD-SMGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGLQYGRSCDIWSVGCVIIEMSCAKPPWNAEK--------HSNHLALIFKIASXXXXXXXXXXLCPGLRDVALRCLELQPSDRPVARDLLKHP</Hsp_qseq>
      <Hsp_hseq>PENVLYVDKSENSPLVIADFGIAKQLK----GEEDLIYKAAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSPFIAESVEGFMEECTASRYPVTFHMP-------YWDNISIDVKRFILKALRLNPADRPTATELLDDP</Hsp_hseq>
      <Hsp_midline>P   L VD S    L IADFG A +L     G  +   +  G++ ++APEVL    +G+ CDIWS+G +   + C   P+ AE          ++   + F +            +   ++   L+ L L P+DRP A +LL  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>4.64428e-11</Hsp_evalue>
      <Hsp_query-from>2101</Hsp_query-from>
      <Hsp_query-to>2490</Hsp_query-to>
      <Hsp_hit-from>183</Hsp_hit-from>
      <Hsp_hit-to>309</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>132</Hsp_align-len>
      <Hsp_qseq>WLRGQQIGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNI--IRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIKA</Hsp_qseq>
      <Hsp_hseq>YLRIMQVGEGTYGKVYKAKNTNTEKLVALKKL---RLQGEREGFPITSIRE-IKLLQSFDHPNVSTIKEIMVESQKTVYMIF-EYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKG</Hsp_hseq>
      <Hsp_midline>+LR  Q+G G +   ++A++  T  L+A+K++   R     +   + ++RE I+++   DHPN+  I+ +    +K+ Y +F E+        LLNK             +QLL G+ YLH N+++HRD+K </Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>6.56744e-07</Hsp_evalue>
      <Hsp_query-from>2719</Hsp_query-from>
      <Hsp_query-to>2994</Hsp_query-to>
      <Hsp_hit-from>310</Hsp_hit-from>
      <Hsp_hit-to>396</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>93</Hsp_align-len>
      <Hsp_qseq>ANLLVDSMGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGL-QYGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKI</Hsp_qseq>
      <Hsp_hseq>SNILIDNQGN-LKITDFGLARKMNSRA----DYTNRVI-TLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKI</Hsp_hseq>
      <Hsp_midline>+N+L+D+ G  L+I DFG A ++ S+     ++  +++ T+ +  PE+L G   YG   D+W  GC+++E+      +        +  IFKI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>5.27076e-11</Hsp_evalue>
      <Hsp_query-from>2101</Hsp_query-from>
      <Hsp_query-to>2490</Hsp_query-to>
      <Hsp_hit-from>23</Hsp_hit-from>
      <Hsp_hit-to>147</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>131</Hsp_align-len>
      <Hsp_qseq>WLRGQQIGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDH-PNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIKA</Hsp_qseq>
      <Hsp_hseq>FKRTEVIGRGKFGVVYKGYNVKTGRVYAIK----VLNLDSDSDEV-EDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLL-RPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKA</Hsp_hseq>
      <Hsp_midline>+ R + IG G F   ++  ++ TG + A+K    V N  S+ DEV + ++ EI+ ++ L    NI R  G+  + ++  + +E  AGGS+ +LL + G   E+ +   + +LL  L  +H + +IHRDIKA</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>3.6414e-09</Hsp_evalue>
      <Hsp_query-from>2719</Hsp_query-from>
      <Hsp_query-to>3132</Hsp_query-to>
      <Hsp_hit-from>148</Hsp_hit-from>
      <Hsp_hit-to>278</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>139</Hsp_align-len>
      <Hsp_qseq>ANLLVDSMGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEV-LRGLQYGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKIASXXXXXXXXXXLCPGLRDVALRCLELQPSDRPVARDLLKHPVFRA</Hsp_qseq>
      <Hsp_hseq>ANVLITNEGN-VKLCDFGVAAQVNQTSLR----RQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIK---SKPPRLEDRSYSTSLKEFIALCLDEDPKERLSADDLLKSKFIRA</Hsp_hseq>
      <Hsp_midline>AN+L+ + G  +++ DFG AA++          +  + GT  +MAPEV + G+ Y    DIWS+G    E++   PP+   +    + LI K   +        +    L++    CL+  P +R  A DLLK    RA</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>6.80171e-11</Hsp_evalue>
      <Hsp_query-from>2110</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>182</Hsp_hit-from>
      <Hsp_hit-to>305</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>126</Hsp_align-len>
      <Hsp_qseq>GQQIGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>GSVIGDGAYSTVMLATSIDTKKRYAAKVLN--KEYLIRQKKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIK</Hsp_hseq>
      <Hsp_midline>G  IG GA+S+   A  I T    A K +   +     Q +V     E+  +    + P+++R+     ++S+    +E+   G   +L+ KYG   E     Y  Q++  + YLHSN +IHRDIK</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>1.38641e-07</Hsp_evalue>
      <Hsp_query-from>2722</Hsp_query-from>
      <Hsp_query-to>2955</Hsp_query-to>
      <Hsp_hit-from>308</Hsp_hit-from>
      <Hsp_hit-to>391</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>25</Hsp_identity>
      <Hsp_positive>43</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>85</Hsp_align-len>
      <Hsp_qseq>NLLVDSMGQRLRIADFGAAARLASKGTGAGEFQGQL-------LGTIAFMAPEVLRGLQYGRSCDIWSVGCVIIEMSCAKPPWNA</Hsp_qseq>
      <Hsp_hseq>NILLDG-EMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPFKA</Hsp_hseq>
      <Hsp_midline>N+L+D    ++++ DFG A  L        + +  L       +GT  +++PE+L        CDIW+ GC++ +M   KPP+ A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>1.37567e-10</Hsp_evalue>
      <Hsp_query-from>2041</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>180</Hsp_hit-from>
      <Hsp_hit-to>330</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>159</Hsp_align-len>
      <Hsp_qseq>TSDVGLEHTRARQPYQEGAEWLRGQQIGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVV----------ISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>TTSAAIRKLNKTRPVSFFDKYLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKN---KQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDD-----GELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIK</Hsp_hseq>
      <Hsp_midline>T+   +      +P     ++L G+++G G ++   +A++  TG  +AVK     +N   +++   +  REE  ++ R+ HPNI+ +L +  E  + +   +++    + +     G   ER+V           +  +QLL GL YLH   +IHRDIK</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>2.84036e-08</Hsp_evalue>
      <Hsp_query-from>2734</Hsp_query-from>
      <Hsp_query-to>2958</Hsp_query-to>
      <Hsp_hit-from>355</Hsp_hit-from>
      <Hsp_hit-to>424</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>41</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>75</Hsp_align-len>
      <Hsp_qseq>DSMGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGLQYGRSCDIWSVGCVIIEMSCAKPPWNAE</Hsp_qseq>
      <Hsp_hseq>DEIDIQVKIADFGLA-----KFTGEMQFTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVILYVCLCGFPPFSDQ</Hsp_hseq>
      <Hsp_midline>D +  +++IADFG A     K TG  +F   L GT +++APEVL    Y    D+WS G ++    C  PP++ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>1.58771e-10</Hsp_evalue>
      <Hsp_query-from>2119</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>204</Hsp_hit-from>
      <Hsp_hit-to>321</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>123</Hsp_align-len>
      <Hsp_qseq>IGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>VGQGAFATVKKAIERTTGKTFAVKIISK-RKVIGNMDGVTR----ELEVLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLK</Hsp_hseq>
      <Hsp_midline>+G GAF++  +A +  TG   AVK ++  R      D V +    E+ ++ +L+HP I+R+ G   +  +Y + +E+++GG + + +  +G   E        Q+L  + Y+HS  + HRD+K</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>1.65262e-07</Hsp_evalue>
      <Hsp_query-from>2752</Hsp_query-from>
      <Hsp_query-to>3120</Hsp_query-to>
      <Hsp_hit-from>335</Hsp_hit-from>
      <Hsp_hit-to>464</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>LRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGL-------------QYGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKIASXXXXXXXXXXLCPGLRDVALRCLELQPSDRPVARDLLKHP</Hsp_qseq>
      <Hsp_hseq>VKITDFGLA-----KVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGR-GSYHEGPLKDFRISEEARDFIDSLLQVDPNNRSTAAKALNHP</Hsp_hseq>
      <Hsp_midline>++I DFG A     K  G G F     GT+A++APEV+RG              +Y    D+WS+GC++  +     P++          I +  S    P     +    RD     L++ P++R  A   L HP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>2.02097e-10</Hsp_evalue>
      <Hsp_query-from>2119</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>76</Hsp_hit-from>
      <Hsp_hit-to>195</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>123</Hsp_align-len>
      <Hsp_qseq>IGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>LGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQ---VEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLK</Hsp_hseq>
      <Hsp_midline>+G G+F      + +  G   A+K +   +    +Q   V+   +E RM+  ++HP +IRM G   +  N  + ++++ GG + +LL K   F   V   Y  +++  L YLH++ +I+RD+K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>2.70102e-10</Hsp_evalue>
      <Hsp_query-from>2116</Hsp_query-from>
      <Hsp_query-to>2490</Hsp_query-to>
      <Hsp_hit-from>625</Hsp_hit-from>
      <Hsp_hit-to>742</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>125</Hsp_align-len>
      <Hsp_qseq>QIGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIKA</Hsp_qseq>
      <Hsp_hseq>KIGQGASGGVYTAYEIGTNVSVAIKQMNL------EKQPKKELIINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVT-HCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKS</Hsp_hseq>
      <Hsp_midline>+IG GA    + A +IGT   +A+KQ+        E+    + +  EI +M    HPNI+  + +   K +  + +E+M GGS+ +++  +    E  + +   + L GL +LHS  ++HRDIK+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>1.62381e-09</Hsp_evalue>
      <Hsp_query-from>2722</Hsp_query-from>
      <Hsp_query-to>3111</Hsp_query-to>
      <Hsp_hit-from>744</Hsp_hit-from>
      <Hsp_hit-to>866</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>130</Hsp_align-len>
      <Hsp_qseq>NLLVDSMGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGLQYGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKIASXXXXXXXXXXLCPGLRDVALRCLELQPSDRPVARDLL</Hsp_qseq>
      <Hsp_hseq>NILL-SMEGDIKLTDFGFCAQINELNLK----RTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPPYLNETPLRALYLI--ATNGTPKLKEPENLSSSLKKFLDWCLCVEPEDRASATELL</Hsp_hseq>
      <Hsp_midline>N+L+ SM   +++ DFG  A++          +  ++GT  +MAPEV+   +YG   DIWS+G +IIEM   +PP+  E     L LI    + T     P  L   L+     CL ++P DR  A +LL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>2.75676e-10</Hsp_evalue>
      <Hsp_query-from>2722</Hsp_query-from>
      <Hsp_query-to>3120</Hsp_query-to>
      <Hsp_hit-from>347</Hsp_hit-from>
      <Hsp_hit-to>479</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>140</Hsp_align-len>
      <Hsp_qseq>NLLVDSMGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGLQYGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLA---LIFKIASXXXXXXXXXXL----CPGLRDVALRCLELQPSDRPVARDLLKHP</Hsp_qseq>
      <Hsp_hseq>NILLNEKGE-IKLCDFGVS------GEAVNSLAMTFTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRFPFESDKITQNVAPIELLTMILTFSPQLKDEPELDISWSKTFRSFIDYCLKKDARERPSPRQMLKHP</Hsp_hseq>
      <Hsp_midline>N+L++  G+ +++ DFG +      G           GT  +MAPE ++G  Y  +CD+WS+G  ++E++  + P+ ++K + ++A   L+  I + +      P L        R     CL+    +RP  R +LKHP</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>1.2291e-08</Hsp_evalue>
      <Hsp_query-from>2119</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>220</Hsp_hit-from>
      <Hsp_hit-to>344</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>129</Hsp_align-len>
      <Hsp_qseq>IGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFI--EWMAGGSV----ANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>LGEGAGGSVAKCRLKNGKKVFALKTI----NTMNTDPEYQKQIFRELQFNKSFKSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIK</Hsp_hseq>
      <Hsp_midline>+G GA  S  + +      + A+K +    NT +   E  + +  E++         I++  G   ++ + +++I  E+M G S+     NLL + G   ERV+    E +LRGL+YLH  ++IHRDIK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>3.38381e-10</Hsp_evalue>
      <Hsp_query-from>2755</Hsp_query-from>
      <Hsp_query-to>3120</Hsp_query-to>
      <Hsp_hit-from>362</Hsp_hit-from>
      <Hsp_hit-to>476</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>124</Hsp_align-len>
      <Hsp_qseq>RIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGLQYGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKIASXXXXXXXX--XXLCPGLRDVALRCLELQPSDRPVARDLLKHP</Hsp_qseq>
      <Hsp_hseq>KLADFGLSKQIFSKNTKTP------CGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTMLCGFPPFYDEKID---TLTEKISRGEYTFLKPWWDEISAGAKNAVAKLLELEPSKRYDIDQFLDDP</Hsp_hseq>
      <Hsp_midline>++ADFG + ++ SK T          GT+ + APEV++   Y    D+W +GCV+  M C  PP+  EK      L  KI+        P    +  G ++   + LEL+PS R      L  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>4.38703e-10</Hsp_evalue>
      <Hsp_query-from>2065</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>3</Hsp_hit-from>
      <Hsp_hit-to>140</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>TRARQPYQEGAEWLRGQQIGLGAFSSCFQAQDIGT-GTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>SRKRSPH----DFIFKEELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLK</Hsp_hseq>
      <Hsp_midline>+R R P+    +++  +++G G++S+ F+A D  +   + A+K  +        + + V   +  + ++++  H  II++     ++ N    +++  GG + +LL+K G F++     +  QL+  L ++HS+ +IHRD+K</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>58.5362</Hsp_bit-score>
      <Hsp_score>140</Hsp_score>
      <Hsp_evalue>4.28644e-09</Hsp_evalue>
      <Hsp_query-from>2722</Hsp_query-from>
      <Hsp_query-to>3126</Hsp_query-to>
      <Hsp_hit-from>143</Hsp_hit-from>
      <Hsp_hit-to>293</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>152</Hsp_align-len>
      <Hsp_qseq>NLLVDSMGQRLRIADFGAAA-----------RLASKGTGAGEFQG--QLLGTIAFMAPEVLRGLQYGRSCDIWSVGCVIIEMSCAKPPWNAEKH----SNHLALIFKIASXXXXXXXXXXLCPGLRDVALRCLELQPSDRPVARDLLKHPVF</Hsp_qseq>
      <Hsp_hseq>NVLLDRDG-RLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPFRGENELKTFEKIVALDYPWGPNNRINNSTSPINPLVINLVQKILVIEVNERISLEQIKRHPYF</Hsp_hseq>
      <Hsp_midline>N+L+D  G RL I DFGAAA           +  S   G+ + Q     +GT  +++PE+L   Q G   DIW++GC+I +    +PP+  E         +AL +              + P + ++  + L ++ ++R     + +HP F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>4.81648e-10</Hsp_evalue>
      <Hsp_query-from>2722</Hsp_query-from>
      <Hsp_query-to>2985</Hsp_query-to>
      <Hsp_hit-from>698</Hsp_hit-from>
      <Hsp_hit-to>780</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>88</Hsp_align-len>
      <Hsp_qseq>NLLVDSMGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGLQYGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALI</Hsp_qseq>
      <Hsp_hseq>NVLLDTRA-RVKITDFGFCARLTDKRSK----RATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLI</Hsp_hseq>
      <Hsp_midline>N+L+D+   R++I DFG  ARL  K +     +  ++GT  +MAPEV++  +Y    D+WS+G + IEM   +PP+  E     L LI</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>1.80279e-06</Hsp_evalue>
      <Hsp_query-from>2170</Hsp_query-from>
      <Hsp_query-to>2490</Hsp_query-to>
      <Hsp_hit-from>588</Hsp_hit-from>
      <Hsp_hit-to>696</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>116</Hsp_align-len>
      <Hsp_qseq>GTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFI--EWMAGGSVANLL-------NKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIKA</Hsp_qseq>
      <Hsp_hseq>GDKVAIKQMVLSKQPRKE------LIVNEILVMKDSRHKNIVNFLEAYL-RTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKS</Hsp_hseq>
      <Hsp_midline>G  +A+KQ+   +    E       +  EI +M    H NI+  L A   +++ +L++  E+M GGS+ +++       N + P  E  +   V +  +GL +LH   +IHRDIK+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>6.28694e-10</Hsp_evalue>
      <Hsp_query-from>2119</Hsp_query-from>
      <Hsp_query-to>2490</Hsp_query-to>
      <Hsp_hit-from>24</Hsp_hit-from>
      <Hsp_hit-to>144</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>126</Hsp_align-len>
      <Hsp_qseq>IGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNK--YGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIKA</Hsp_qseq>
      <Hsp_hseq>IGRGNFGDVYKAVDRVTQEIVAIKVVN-----LEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKA</Hsp_hseq>
      <Hsp_midline>IG G F   ++A D  T  ++A+K V          DE ++ L +EI  ++ L  P I   +    E  +  + +E+  GGS ++LL +       E  V   + ++  GL YLH  + IHRDIKA</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YAR018C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:170396:171703:-1 gene:YAR018C transcript:YAR018C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN3 description:Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol [Source:SGD;Acc:S000000071]</Hit_def>
  <Hit_accession>YAR018C</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>1.00365e-09</Hsp_evalue>
      <Hsp_query-from>2752</Hsp_query-from>
      <Hsp_query-to>3000</Hsp_query-to>
      <Hsp_hit-from>227</Hsp_hit-from>
      <Hsp_hit-to>302</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>83</Hsp_align-len>
      <Hsp_qseq>LRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGLQYGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKIAS</Hsp_qseq>
      <Hsp_hseq>VKLGDFGLAKSLET----SIQFATTYVGTPYYMSPEVLMDQPYSPLSDIWSLGCVIFEMCSLHPPFQAK---NYLELQTKIKN</Hsp_hseq>
      <Hsp_midline>+++ DFG A  L +    + +F    +GT  +M+PEVL    Y    DIWS+GCVI EM    PP+ A+   N+L L  KI +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>1.05533e-09</Hsp_evalue>
      <Hsp_query-from>2722</Hsp_query-from>
      <Hsp_query-to>3129</Hsp_query-to>
      <Hsp_hit-from>354</Hsp_hit-from>
      <Hsp_hit-to>489</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>143</Hsp_align-len>
      <Hsp_qseq>NLLVDSMGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGLQYGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLA---LIFKIASXXXXXX----XXXXLCPGLRDVALRCLELQPSDRPVARDLLKHPVFR</Hsp_qseq>
      <Hsp_hseq>NILLNENGQ-VKLCDFGVS------GEAVNSLATTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANGKFPCSSEKMAANIAPFELLMWILTFTPELKDEPESNIIWSPSFKSFIDYCLKKDSRERPSPRQMINHPWIK</Hsp_hseq>
      <Hsp_midline>N+L++  GQ +++ DFG +      G           GT  +MAPE ++G  Y  + D+WS+G  I+E++  K P ++EK + ++A   L+  I + T              P  +     CL+    +RP  R ++ HP  +</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>9.27724e-09</Hsp_evalue>
      <Hsp_query-from>2119</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>227</Hsp_hit-from>
      <Hsp_hit-to>351</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>129</Hsp_align-len>
      <Hsp_qseq>IGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFI--EWMAGGSV----ANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>LGEGAGGSVSKCKLKNGSKIFALK----VINTLNTDPEYQKQIFRELQFNRSFQSEYIVRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIK</Hsp_hseq>
      <Hsp_midline>+G GA  S  + +      + A+K    V NT +   E  + +  E++         I+R  G   +  N +++I  E+M G S+     NLL + G   E+V+    E +LRGL+YLH  ++IHRDIK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>1.46796e-09</Hsp_evalue>
      <Hsp_query-from>2119</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>94</Hsp_hit-from>
      <Hsp_hit-to>213</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>123</Hsp_align-len>
      <Hsp_qseq>IGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>LGTGSFGRVHLIRSNHNGRFYALK--TLKKHTIVKLKQVEHT-NDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLK</Hsp_hseq>
      <Hsp_midline>+G G+F      +    G   A+K  T  ++T  +  +V  T  +E RM+S + HP IIRM G   +     + ++++ GG + +LL K   F   V   Y  ++   L YLHS  +I+RD+K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>1.75979e-09</Hsp_evalue>
      <Hsp_query-from>2722</Hsp_query-from>
      <Hsp_query-to>3090</Hsp_query-to>
      <Hsp_hit-from>282</Hsp_hit-from>
      <Hsp_hit-to>406</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>129</Hsp_align-len>
      <Hsp_qseq>NLLVDSMGQRLRIADFGAAARLASKGTGAGEFQGQ------LLGTIAFMAPEVLRGLQYGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKIASXXXXXXXXXXLCPGLRDVALRCLELQPSDR</Hsp_qseq>
      <Hsp_hseq>NCLLNQRGH-LVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTG---SNHKVIINKIQQNKQGPKIPFYLSEGMKDILNALLKKETAKR</Hsp_hseq>
      <Hsp_midline>N L++  G  L + DFG + + A+      E          ++GT  + APE+L G  Y ++CD +S+GC++ +M   KPP+     SNH  +I KI      P +P  L  G++D+    L+ + + R</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>2.43203e-08</Hsp_evalue>
      <Hsp_query-from>2119</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>134</Hsp_hit-from>
      <Hsp_hit-to>279</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>146</Hsp_align-len>
      <Hsp_qseq>IGLGAFSSCFQAQDIGTGTLMAVKQV----TYVRNTASE---QDEV----------------VQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>LGQGAYGKVLLVKDVNTSKLYAMKQLRKAEILISQTATDSKREDEDKNDGNNNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLK</Hsp_hseq>
      <Hsp_midline>+G GA+      +D+ T  L A+KQ+      +  TA++   +DE                 ++    E  ++S ++HPNI+++  +  + S   L ++++ GG +   L ++G   E  V  Y  ++   L +LH+  +++RD+K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.5362</Hsp_bit-score>
      <Hsp_score>140</Hsp_score>
      <Hsp_evalue>1.79054e-09</Hsp_evalue>
      <Hsp_query-from>2722</Hsp_query-from>
      <Hsp_query-to>2994</Hsp_query-to>
      <Hsp_hit-from>138</Hsp_hit-from>
      <Hsp_hit-to>224</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>92</Hsp_align-len>
      <Hsp_qseq>NLLVDSMGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGLQ-YGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKI</Hsp_qseq>
      <Hsp_hseq>NLLINKRGQ-LKLGDFGLARAF---GIPVNTFSSEVV-TLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDI</Hsp_hseq>
      <Hsp_midline>NLL++  GQ L++ DFG A      G     F  +++ T+ + AP+VL G + Y  S DIWS GC++ EM   KP +        L LIF I</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>1.83612e-08</Hsp_evalue>
      <Hsp_query-from>2113</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>11</Hsp_hit-from>
      <Hsp_hit-to>135</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>135</Hsp_align-len>
      <Hsp_qseq>QQIGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFH---------ERVVISYVE-QLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>EKLGNGTYATVYKGLNKTTGVYVALKEV----KLDSEEGTPSTAIRE-ISLMKELKHENIVRLYDVIHTENKLTLVFEFMD-----NDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLK</Hsp_hseq>
      <Hsp_midline>+++G G +++ ++  +  TG  +A+K+V       SE+      +RE I +M  L H NI+R+      ++   L  E+M      N L KY             E  ++ Y + QLL+GLA+ H N+++HRD+K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YFL033C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:69115:74427:-1 gene:YFL033C transcript:YFL033C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM15 description:Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase [Source:SGD;Acc:S000001861]</Hit_def>
  <Hit_accession>YFL033C</Hit_accession>
  <Hit_len>1770</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>2.51383e-09</Hsp_evalue>
      <Hsp_query-from>2119</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>800</Hsp_hit-from>
      <Hsp_hit-to>920</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>123</Hsp_align-len>
      <Hsp_qseq>IGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>ISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQ--VTNVKSERAIMMVQSDKPYVARLFASFQNKDNLFLVMEYLPGGDLATLIKMMGYLPDQWAKQYLTEIVVGVNDMHQNGIIHHDLK</Hsp_hseq>
      <Hsp_midline>I  GA+ S + A+   TG   A+K +      A  Q  V     E   MM + D P + R+  +   K N  L +E++ GG +A L+   G   ++    Y+ +++ G+  +H N +IH D+K</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>1.47318e-06</Hsp_evalue>
      <Hsp_query-from>2824</Hsp_query-from>
      <Hsp_query-to>3129</Hsp_query-to>
      <Hsp_hit-from>1146</Hsp_hit-from>
      <Hsp_hit-to>1255</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>110</Hsp_align-len>
      <Hsp_qseq>QLLGTIAFMAPEVLRGL-QYGRSCDIWSVGCVIIEMSCAKPPWNAEK----HSNHLALIFKIASXXXXXXXXXXLCPGLRDVALRCLELQPSDRPVAR---DLLKHPVFR</Hsp_qseq>
      <Hsp_hseq>KFFGTPDYLAPETIEGKGEDNKQCDWWSVGCIFFELLLGYPPFHAETPDAVFKKILSGVIQWPEFKNEEEEREFLTPEAKDLIEKLLVVDPAKRLGAKGIQEIKDHPYFK</Hsp_hseq>
      <Hsp_midline>+  GT  ++APE + G  +  + CD WSVGC+  E+    PP++AE         L+ + +             L P  +D+  + L + P+ R  A+   ++  HP F+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>6.70362e-09</Hsp_evalue>
      <Hsp_query-from>2722</Hsp_query-from>
      <Hsp_query-to>3135</Hsp_query-to>
      <Hsp_hit-from>244</Hsp_hit-from>
      <Hsp_hit-to>372</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>143</Hsp_align-len>
      <Hsp_qseq>NLLVDSMGQRLRIADFGAAARLASKGTGAGEFQGQLL----GTIAFMAPEVLRGLQY-GRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKIASXXXXXXXXXXLCPGLRDVALRCLELQPSDRPVARDLLKHPVFRAW</Hsp_qseq>
      <Hsp_hseq>NLLLDKKNRRIKIADFGMAAL---------ELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDD---NIKKLLLKVQS--GKYQMPSNLSSEARDLISKILVIDPEKRITTQEILKHPLIKKY</Hsp_hseq>
      <Hsp_midline>NLL+D   +R++IADFG AA          E   +LL    G+  + +PE++ G  Y G   D+WS G V+  +     P+N +   N   L+ K+ S      +P  L    RD+  + L + P  R   +++LKHP+ + +</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>8.27196e-08</Hsp_evalue>
      <Hsp_query-from>2101</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>81</Hsp_hit-from>
      <Hsp_hit-to>241</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>161</Hsp_align-len>
      <Hsp_qseq>WLRGQQIGLGAFSSCFQAQDIGTGTLMAVKQVT------------YVRNTAS----------------EQDEVVQT----LREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>WKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLK</Hsp_hseq>
      <Hsp_midline>W  G+ +G G+      A+++ TG L A+K V              V N+ S                E     QT    +  EI +M  + H N++ +      KS   L +E++ GG + + L   G   ER  I Y +Q++ G++Y HS  + HRD+K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>1.07922e-08</Hsp_evalue>
      <Hsp_query-from>2098</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>6</Hsp_hit-from>
      <Hsp_hit-to>131</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>130</Hsp_align-len>
      <Hsp_qseq>EWLRGQQIGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>EYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEI----KTSEFKDGLDMSAIREVKYLQEMQHPNVIELIDIFMAYDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLK</Hsp_hseq>
      <Hsp_midline>E+ + +++G G ++  +      TG  +A+K++     T+  +D +  +   E++ +  + HPN+I ++       N NL +E++       + +K   F    + +++   LRG+ + H N ++HRD+K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>1.44234e-08</Hsp_evalue>
      <Hsp_query-from>2722</Hsp_query-from>
      <Hsp_query-to>3135</Hsp_query-to>
      <Hsp_hit-from>158</Hsp_hit-from>
      <Hsp_hit-to>321</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>165</Hsp_align-len>
      <Hsp_qseq>NLLVDSMGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGLQY-GRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKIASXXXXXX----------------------XXXXLCPGLRDVAL----RCLELQPSDRPVARDLLKHPVFRAW</Hsp_qseq>
      <Hsp_hseq>NLLVNSDCQ-LKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIPGRSFESILPGANPEALELLKKMLEFDPKKRITVEDALEHPYLSMW</Hsp_hseq>
      <Hsp_midline>NLLV+S  Q L+I +FG +   +        F    + +I + APE+L   Q   ++ DIWS GC++ E+   KP +  + + +HL  I +I  T    T                         ++ PG    AL    + LE  P  R    D L+HP    W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>3.69258e-08</Hsp_evalue>
      <Hsp_query-from>2722</Hsp_query-from>
      <Hsp_query-to>3126</Hsp_query-to>
      <Hsp_hit-from>254</Hsp_hit-from>
      <Hsp_hit-to>391</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>144</Hsp_align-len>
      <Hsp_qseq>NLLVDSMGQRLRIADFGAAARLASKGTGAGEFQ---------GQLLGTIAFMAPEVLRGLQYGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKIASXXXXXXXXXXLCPGLRDVALRCLELQPSDRPVARDLLKHPVF</Hsp_qseq>
      <Hsp_hseq>NILLDK-NMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKI-----QYAFTAGFPQIVKDLVKKLLVRDPNDRLTIKQIKAHLFF</Hsp_hseq>
      <Hsp_midline>N+L+D    ++++ DFG A  L  + +   + +            +GT  +++PE+L        CDIW+ GC++ +M   KPP+ A         + KI                ++D+  + L   P+DR   + +  H  F</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>1.0409e-06</Hsp_evalue>
      <Hsp_query-from>2110</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>128</Hsp_hit-from>
      <Hsp_hit-to>251</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>126</Hsp_align-len>
      <Hsp_qseq>GQQIGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>GEQLGDGSYSSVVLATARDSGKKYAVKVLS--KEYLIRQKKVKYVTVEKLALQKLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIK</Hsp_hseq>
      <Hsp_midline>G+Q+G G++SS   A    +G   AVK ++  +     Q +V     E++ +        I ++     ++++    +E+   G    L+ KYG  +E     Y  Q++  +  LH+  +IHRDIK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>3.76342e-08</Hsp_evalue>
      <Hsp_query-from>2719</Hsp_query-from>
      <Hsp_query-to>3114</Hsp_query-to>
      <Hsp_hit-from>141</Hsp_hit-from>
      <Hsp_hit-to>261</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>139</Hsp_align-len>
      <Hsp_qseq>ANLLVDSMGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMA------PEV-LRGLQYGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKIASXXXXXXXXXXLCPGLRDVALRCLELQPSDRPVARDLLK</Hsp_qseq>
      <Hsp_hseq>SNLLINSNCD-LKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHS------------DNDLRCIE-----SPRAREYIK</Hsp_hseq>
      <Hsp_midline>+NLL++S    L++ DFG A  +        E  GQ  G   ++A      PEV L   +Y R+ D+WS GC++ E+   +P +    + + L LIF I  T  +            D  LRC+E      P AR+ +K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>4.08623e-08</Hsp_evalue>
      <Hsp_query-from>2251</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>210</Hsp_hit-from>
      <Hsp_hit-to>292</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>83</Hsp_align-len>
      <Hsp_qseq>EEIRMMSRLDHPNIIRMLGATCEKSNY-NLFIEWMAGGSVANLLNK---YGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>KEARILLRLDHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLK</Hsp_hseq>
      <Hsp_midline>+E R++ RLDHPNII++    C+++N+  +F + + GG + + L K        E   +  V Q+L+ L YLH   ++HRD+K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>5.18193e-08</Hsp_evalue>
      <Hsp_query-from>2755</Hsp_query-from>
      <Hsp_query-to>3135</Hsp_query-to>
      <Hsp_hit-from>298</Hsp_hit-from>
      <Hsp_hit-to>417</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>127</Hsp_align-len>
      <Hsp_qseq>RIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGLQYGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKIASXXXXXXXXXXLCPGLRDVALRCLELQPSDRPVARDLLKHPVFRAW</Hsp_qseq>
      <Hsp_hseq>KLMDFGLAKKLRNNTAKTP------CGTIEYVASEVFTSKRYSMKVDMWSIGCVLFTLLCGYPPF-YEKNEKTLLKKISRGDYEFLAPWWDNISSGAKNAVTHLLEVDPNKRYDIDDFLNDPWLNSY</Hsp_hseq>
      <Hsp_midline>++ DFG A +L +             GTI ++A EV    +Y    D+WS+GCV+  + C  PP+  EK+   L                  +  G ++     LE+ P+ R    D L  P   ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>5.31997e-08</Hsp_evalue>
      <Hsp_query-from>2722</Hsp_query-from>
      <Hsp_query-to>2994</Hsp_query-to>
      <Hsp_hit-from>158</Hsp_hit-from>
      <Hsp_hit-to>248</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>92</Hsp_align-len>
      <Hsp_qseq>NLLVDSMGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGLQ-YGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKI</Hsp_qseq>
      <Hsp_hseq>NLLVNADCQ-LKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQV</Hsp_hseq>
      <Hsp_midline>NLLV++  Q L+I DFG A   +       +F  + + T  + APE++   Q Y ++ D+WS GC++ E    KP +  + + N L  I ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>6.22887e-08</Hsp_evalue>
      <Hsp_query-from>2119</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>29</Hsp_hit-from>
      <Hsp_hit-to>146</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>123</Hsp_align-len>
      <Hsp_qseq>IGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>VGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAV----LAKRTYRELKLLKHLRHENLICLQDIFLSPLEDIYFVTELQGTDLHRLLQT-RPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLK</Hsp_hseq>
      <Hsp_midline>+G+GAF     A D  T   +A+K++    +TA     + +    E++++  L H N+I +            F+  + G  +  LL    P  ++ V  ++ Q+LRGL Y+HS  +IHRD+K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>6.99784e-08</Hsp_evalue>
      <Hsp_query-from>2722</Hsp_query-from>
      <Hsp_query-to>2985</Hsp_query-to>
      <Hsp_hit-from>512</Hsp_hit-from>
      <Hsp_hit-to>594</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>88</Hsp_align-len>
      <Hsp_qseq>NLLVDSMGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGLQYGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALI</Hsp_qseq>
      <Hsp_hseq>NILLNSQG-LVKITDFGFCVELTEKRSK----RATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLI</Hsp_hseq>
      <Hsp_midline>N+L++S G  ++I DFG    L  K +     +  ++GT  +MAPE++    Y    D+WS+G ++IEM   +PP+  E     L LI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>1.30651e-07</Hsp_evalue>
      <Hsp_query-from>2719</Hsp_query-from>
      <Hsp_query-to>3120</Hsp_query-to>
      <Hsp_hit-from>489</Hsp_hit-from>
      <Hsp_hit-to>621</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>139</Hsp_align-len>
      <Hsp_qseq>ANLLVDSMGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGLQYGRSC-----DIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKIASXXXXXXXXXXLCPGLRDVALRCLELQPSDRPVARDLLKHP</Hsp_qseq>
      <Hsp_hseq>TNILCSANQGTVKLCDFGVSGNLVA------SLAKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYPPETYDNIFSQLSAIVDGPPPRLPSDKFSSDAQDFVSLCLQKIPERRPTYAALTEHP</Hsp_hseq>
      <Hsp_midline> N+L  +    +++ DFG +  L +            +G  ++MAPE ++ L   R+      DIWS+G  I+EM+  + P+  E + N  + +  I                 +D    CL+  P  RP    L +HP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>1.41401e-07</Hsp_evalue>
      <Hsp_query-from>2236</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>129</Hsp_hit-from>
      <Hsp_hit-to>212</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>VQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>VEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLK</Hsp_hseq>
      <Hsp_midline>V+   +E  M+S + HP IIRM G   +     + ++++ GG + +LL K   F   V   Y  ++   L YLHS  +I+RD+K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>1.62517e-07</Hsp_evalue>
      <Hsp_query-from>2719</Hsp_query-from>
      <Hsp_query-to>2994</Hsp_query-to>
      <Hsp_hit-from>147</Hsp_hit-from>
      <Hsp_hit-to>241</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>96</Hsp_align-len>
      <Hsp_qseq>ANLLVDSMGQRLRIADFGAAARLASKGTGAGE---FQGQLLGTIAFMAPEVLRGLQ-YGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKI</Hsp_qseq>
      <Hsp_hseq>SNLLLNS-NCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEV</Hsp_hseq>
      <Hsp_midline>+NLL++S    L++ DFG A  LAS          F  + + T  + APE++   Q Y  + DIWS GC++ EM   KP +    + + L LI ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>4.32542e-07</Hsp_evalue>
      <Hsp_query-from>2089</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>4</Hsp_hit-from>
      <Hsp_hit-to>138</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>EGAEWLRGQQIGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGAT-CEKSNYNLFIEWMAGGSVANL--LNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>ELANYKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIR-LESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLK</Hsp_hseq>
      <Hsp_midline>E A + R +++G G +   ++A D+  G    V  +  +R   SE + V  T   EI ++  L   NI+R+      +     L  E++       +  + K  P    +V  ++ QL +G+AY HS++++HRD+K</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>5.70414e-07</Hsp_evalue>
      <Hsp_query-from>2722</Hsp_query-from>
      <Hsp_query-to>2994</Hsp_query-to>
      <Hsp_hit-from>141</Hsp_hit-from>
      <Hsp_hit-to>227</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>92</Hsp_align-len>
      <Hsp_qseq>NLLVDSMGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRG-LQYGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKI</Hsp_qseq>
      <Hsp_hseq>NLLINKDGN-LKLGDFGLARAF---GVPLRAYTHEIV-TLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRV</Hsp_hseq>
      <Hsp_midline>NLL++  G  L++ DFG A      G     +  +++ T+ + APEVL G  QY    D WS+GC+  EM   KP ++ +   + +  IF++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YDL028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:400997:403291:-1 gene:YDL028C transcript:YDL028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MPS1 description:Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]</Hit_def>
  <Hit_accession>YDL028C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>6.85182e-07</Hsp_evalue>
      <Hsp_query-from>2752</Hsp_query-from>
      <Hsp_query-to>2985</Hsp_query-to>
      <Hsp_hit-from>576</Hsp_hit-from>
      <Hsp_hit-to>666</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>42</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>93</Hsp_align-len>
      <Hsp_qseq>LRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGLQY---------------GRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALI</Hsp_qseq>
      <Hsp_hseq>LKIIDFGIANAVPEHTVNI--YRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYGKPPYGSFQGQNRLLAI</Hsp_hseq>
      <Hsp_midline>L+I DFG A  +         ++   +GT  +MAPE L  + Y               GR  D+WS GC+I +M   KPP+ + +  N L  I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>8.02432e-07</Hsp_evalue>
      <Hsp_query-from>2068</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>306</Hsp_hit-from>
      <Hsp_hit-to>451</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>150</Hsp_align-len>
      <Hsp_qseq>RARQPYQEGAEWLRGQQI-GLGAFSSCFQAQDIGTGT--------LMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCE-KSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>KDRQCFAE--KYGRCQEVLGKGAFGVVRICQKKNVSSQDGNKSEKLYAVKE--FKRRTSESAEKYSKRLTSEFCISSSLHHTNIVTTLDLFQDAKGEYCEVMEYCAGGDLFTLVVAAGKLEYMEADCFFKQLIRGVVYMHEMGVCHRDLK</Hsp_hseq>
      <Hsp_midline>+ RQ + E  ++ R Q++ G GAF      Q     +        L AVK+  + R T+   ++  + L  E  + S L H NI+  L    + K  Y   +E+ AGG +  L+   G         + +QL+RG+ Y+H   + HRD+K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>1.38972e-06</Hsp_evalue>
      <Hsp_query-from>2719</Hsp_query-from>
      <Hsp_query-to>2946</Hsp_query-to>
      <Hsp_hit-from>335</Hsp_hit-from>
      <Hsp_hit-to>403</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>44</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>76</Hsp_align-len>
      <Hsp_qseq>ANLLVDSMGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGLQYGRSCDIWSVGCVIIEMSCAKPP</Hsp_qseq>
      <Hsp_hseq>SNVLINSKGQ-IKLCDFGVSKKLIN------SIADTFVGTSTYMSPERIQGNVYSIKGDVWSLGLMIIELVTGEFP</Hsp_hseq>
      <Hsp_midline>+N+L++S GQ +++ DFG + +L +            +GT  +M+PE ++G  Y    D+WS+G +IIE+   + P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>1.48242e-06</Hsp_evalue>
      <Hsp_query-from>2722</Hsp_query-from>
      <Hsp_query-to>2994</Hsp_query-to>
      <Hsp_hit-from>169</Hsp_hit-from>
      <Hsp_hit-to>255</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>44</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>92</Hsp_align-len>
      <Hsp_qseq>NLLVDSMGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRG-LQYGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKI</Hsp_qseq>
      <Hsp_hseq>NLLVDPETWSLKLCDFGSAKQLKPTEPNVS-----YICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKI</Hsp_hseq>
      <Hsp_midline>NLLVD     L++ DFG+A +L              + +  + APE++ G   Y    DIWS GCV+ E+   +P +  E   + L  I KI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>2.1559e-06</Hsp_evalue>
      <Hsp_query-from>2722</Hsp_query-from>
      <Hsp_query-to>3132</Hsp_query-to>
      <Hsp_hit-from>182</Hsp_hit-from>
      <Hsp_hit-to>308</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>138</Hsp_align-len>
      <Hsp_qseq>NLLVDSMGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGLQY-GRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKIASXXXXXXXXXXLCPGLRDVALRCLELQPSDRPVARDLLKHPVFRA</Hsp_qseq>
      <Hsp_hseq>NLLLDE-HLNVKIADFGLSNIMTD-----GNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDES----IPVLFKNIS-NGVYTLPKFLSPGAAGLIKRMLIVNPLNRISIHEIMQDDWFKV</Hsp_hseq>
      <Hsp_midline>NLL+D     ++IADFG +  +       G F     G+  + APEV+ G  Y G   D+WS G ++  M C + P++ E     + ++FK  S     T+P  L PG   +  R L + P +R    ++++   F+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>2.36641e-06</Hsp_evalue>
      <Hsp_query-from>2098</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>119</Hsp_hit-from>
      <Hsp_hit-to>271</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>153</Hsp_align-len>
      <Hsp_qseq>EWLRGQQIGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNT-----------ASEQD--EVVQTLREEIRMMSR----------LDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>DWEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPPPKNEQDVLERQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLK</Hsp_hseq>
      <Hsp_midline>+W   + +G G+      A+   T  + AVK V                  +EQD  E  + L +EI    R          L HP+I R+       +++ +  E+++GG + + + ++G   E     +   +   L YLH+N ++HRD+K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YLL019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:105686:107899:-1 gene:YLL019C transcript:YLL019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KNS1 description:Protein kinase involved in negative regulation of PolIII transcription; effector kinase of the TOR signaling pathway and phosphorylates Rpc53p to regulate ribosome and tRNA biosynthesis; member of the LAMMER family of protein kinases, which are serine/threonine kinases also capable of phosphorylating tyrosine residues; capable of autophosphorylation [Source:SGD;Acc:S000003942]</Hit_def>
  <Hit_accession>YLL019C</Hit_accession>
  <Hit_len>737</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>2.40703e-06</Hsp_evalue>
      <Hsp_query-from>2752</Hsp_query-from>
      <Hsp_query-to>2994</Hsp_query-to>
      <Hsp_hit-from>486</Hsp_hit-from>
      <Hsp_hit-to>559</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>81</Hsp_align-len>
      <Hsp_qseq>LRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGLQYGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKI</Hsp_qseq>
      <Hsp_hseq>IKIIDFGSA-------IFHYEYHPPVISTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVIGESLYPIHENLEHMAMMQRI</Hsp_hseq>
      <Hsp_midline>++I DFG+A           E+   ++ T  + APE++ GL +   CDIWS+ CV++E+   +  +   ++  H+A++ +I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>3.06058e-06</Hsp_evalue>
      <Hsp_query-from>2059</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>400</Hsp_hit-from>
      <Hsp_hit-to>540</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>145</Hsp_align-len>
      <Hsp_qseq>EHTRARQPYQEGAEWLRGQQIGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDH--PNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>KQTKKRHYGPQDFEVLR--LLGKGTFGQVYQVKKKDTQRIYAMKVLS--KKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLK</Hsp_hseq>
      <Hsp_midline>+ T+ R    +  E LR   +G G F   +Q +   T  + A+K ++  +    +++E+  T+ E   +++      P I+ +  +    ++  L  ++M+GG +   L K G F E     Y+ +L+  L +LH N +++RD+K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>4.18725e-06</Hsp_evalue>
      <Hsp_query-from>2119</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>358</Hsp_hit-from>
      <Hsp_hit-to>477</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>123</Hsp_align-len>
      <Hsp_qseq>IGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNYNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>IGKGAFGEVRLVQKKDTGKIYAMK--TLLKSEMYKKDQLAH-VKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIK</Hsp_hseq>
      <Hsp_midline>IG GAF      Q   TG + A+K  T +++   ++D++   ++ E  +++  D P ++ +  +  +     L +E++ GG +  +L ++  F E V   Y+ + +  +  +H    IHRDIK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>5.01057e-06</Hsp_evalue>
      <Hsp_query-from>2101</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>46</Hsp_hit-from>
      <Hsp_hit-to>177</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>133</Hsp_align-len>
      <Hsp_qseq>WLRGQQIGLGAFSSCFQAQDIGTGTLMAVKQVTYV---RNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSNY-NLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>YIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNII-YLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLK</Hsp_hseq>
      <Hsp_midline>++ G  +G G F          + +    KQV      R+T  +  +    +  EI  +  L HPNII  L    + S Y  + +E+++GG     + +     E        QL+ G+ Y+H   L+HRD+K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>7.57521e-06</Hsp_evalue>
      <Hsp_query-from>2221</Hsp_query-from>
      <Hsp_query-to>2487</Hsp_query-to>
      <Hsp_hit-from>83</Hsp_hit-from>
      <Hsp_hit-to>177</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>96</Hsp_align-len>
      <Hsp_qseq>EQDEVVQTLREEIRM------MSRLDHPNIIRMLGATCEKSNY-NLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQLIHRDIK</Hsp_qseq>
      <Hsp_hseq>KRDSISNDYRKEVKIYREINALKHLSHPNIVK-LEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLK</Hsp_hseq>
      <Hsp_midline>++D +    R+E+++      +  L HPNI++ L    + S Y  + +E+  GG     + K     E        QL+ G+ Y+HS  L+HRD+K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>8.29236e-06</Hsp_evalue>
      <Hsp_query-from>2719</Hsp_query-from>
      <Hsp_query-to>2994</Hsp_query-to>
      <Hsp_hit-from>199</Hsp_hit-from>
      <Hsp_hit-to>298</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>102</Hsp_align-len>
      <Hsp_qseq>ANLLVDSMGQRLRIADFGAAARLA---------SKGTGAGEFQGQLLGTIAFMAPE-VLRGLQYGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKI</Hsp_qseq>
      <Hsp_hseq>ANILIDHNGV-LKLADFGLA-RLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKL</Hsp_hseq>
      <Hsp_midline>AN+L+D  G  L++ADFG A RL            G G+G     ++ T  + APE VL   QY  + DIW VGCV  E    KP    +   +   +IFK+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2132347382</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058265-RA transcript Note:&quot;Similar to Map3k1 Mitogen-activated protein kinase kinase kinase 1 (Rattus norvegicus)&quot; offset:0 AED:0.71 eAED:0.90 QI:0|0|0|0.25|1|1|12|0|726</Iteration_query-def>
  <Iteration_query-len>2181</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1432536210</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058266-RA transcript Note:&quot;Similar to Mier3 Mesoderm induction early response protein 3 (Mus musculus)&quot; offset:149 AED:0.04 eAED:0.04 QI:149|0.81|0.91|1|0.72|0.83|12|3441|589</Iteration_query-def>
  <Iteration_query-len>5360</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>104</Statistics_hsp-len>
      <Statistics_eff-space>3746935894</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058267-RA transcript Note:&quot;Similar to PLPP3 Phospholipid phosphatase 3 (Bos taurus)&quot; offset:0 AED:0.05 eAED:0.05 QI:0|0.6|0.5|0.83|0.6|0.66|6|2971|302</Iteration_query-def>
  <Iteration_query-len>3880</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDR284C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1030550:1031419:-1 gene:YDR284C transcript:YDR284C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DPP1 description:Diacylglycerol pyrophosphate (DGPP) phosphatase; zinc-regulated vacuolar membrane-associated lipid phosphatase, dephosphorylates DGPP to phosphatidate (PA) and Pi, then PA to diacylglycerol; involved in lipid signaling and cell metabolism [Source:SGD;Acc:S000002692]</Hit_def>
  <Hit_accession>YDR284C</Hit_accession>
  <Hit_len>289</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.1814</Hsp_bit-score>
      <Hsp_score>191</Hsp_score>
      <Hsp_evalue>4.84252e-16</Hsp_evalue>
      <Hsp_query-from>70</Hsp_query-from>
      <Hsp_query-to>684</Hsp_query-to>
      <Hsp_hit-from>28</Hsp_hit-from>
      <Hsp_hit-to>239</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>223</Hsp_align-len>
      <Hsp_qseq>VIILNQP--YVSPFHRGFYCDDESIQYPLKGST-ITHQVLYAVGIILP-MASMIVGECVAVRYLKHRPTSFVHSPYVVALYRALGPFLLGMAVSQSFTNVAKFAIGRPRPHFLAVCRPDPAL-LN--------CSAGY---ITDKVKSFYSGHASFAMYTLMYLALYVESRLRWRGAR--ILRPFVEFVLVLMAVYVGLSRVSDYKHHWSDVLVGLLQGAAVA</Hsp_qseq>
      <Hsp_hseq>MILLNYPVYYQQPFERQFYINDLTISHPYATTERVNNNMLFVYSFVVPSLTILIIGSILADR--RH---------LIFILYTSLLGLSLAWFSTSFFTNFIKNWIGRLRPDFLDRCQPVEGLPLDTLFTAKDVCTTKNHERLLDGFRTTPSGHSSESFAGLGYLYFWLCGQLLTESPLMPLWRKMVAFLPLLGAALIALSRTQDYRHHFVDVILGSMLGYIMA</Hsp_hseq>
      <Hsp_midline>+I+LN P  Y  PF R FY +D +I +P   +  + + +L+    ++P +  +I+G  +A R  +H          +  LY +L    L    +  FTN  K  IGR RP FL  C+P   L L+        C+      + D  ++  SGH+S +   L YL  ++  +L        + R  V F+ +L A  + LSR  DY+HH+ DV++G + G  +A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YDR503C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1455042:1455866:-1 gene:YDR503C transcript:YDR503C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:LPP1 description:Lipid phosphate phosphatase; catalyzes Mg(2+)-independent dephosphorylation of phosphatidic acid (PA), lysophosphatidic acid, and diacylglycerol pyrophosphate; involved in control of the cellular levels of phosphatidylinositol and PA [Source:SGD;Acc:S000002911]</Hit_def>
  <Hit_accession>YDR503C</Hit_accession>
  <Hit_len>274</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>2.35869e-07</Hsp_evalue>
      <Hsp_query-from>238</Hsp_query-from>
      <Hsp_query-to>687</Hsp_query-to>
      <Hsp_hit-from>97</Hsp_hit-from>
      <Hsp_hit-to>248</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>166</Hsp_align-len>
      <Hsp_qseq>VRYLKHRPTSFVHSPYVVALYRALGPFLLGMAVSQSFTNVAKFAIGRPRPHFLAVCRPDPALLNCSAGYI--------TDK------VKSFYSGHASFAMYTLMYLALYVESRLRWRGAR--ILRPFVEFVLVLMAVYVGLSRVSDYKHHWSDVLVGLLQGAAVAF</Hsp_qseq>
      <Hsp_hseq>VKRLRERPDGISNDFHF--MHTSILCLMLIISINAALTGALKLIIGNLRPDFVDRCIPDLQKMSDSDSLVFGLDICKQTNKWILYEGLKSTPSGHSSFIVSTMGFTYLW-QRVFTTRNTRSCIWCP-------LLALVVMVSRVIDHRHHWYDV----VSGAVLAF</Hsp_hseq>
      <Hsp_midline>V+ L+ RP    +  +   ++ ++   +L ++++ + T   K  IG  RP F+  C PD   ++ S   +        T+K      +KS  SGH+SF + T+ +  L+ +     R  R  I  P       L+A+ V +SRV D++HHW DV    + GA +AF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2678980664</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058269-RA transcript Note:&quot;Similar to DPH5 Diphthine methyl ester synthase (Homo sapiens)&quot; offset:60 AED:0.43 eAED:0.50 QI:60|0|0.25|1|1|1|4|0|172</Iteration_query-def>
  <Iteration_query-len>579</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YLR172C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:501260:502162:-1 gene:YLR172C transcript:YLR172C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DPH5 description:Methyltransferase required for synthesis of diphthamide; diphthamide is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); not essential for viability; GFP-Dph5p fusion protein localizes to the cytoplasm [Source:SGD;Acc:S000004162]</Hit_def>
  <Hit_accession>YLR172C</Hit_accession>
  <Hit_len>300</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>124.02</Hsp_bit-score>
      <Hsp_score>310</Hsp_score>
      <Hsp_evalue>2.97187e-35</Hsp_evalue>
      <Hsp_query-from>61</Hsp_query-from>
      <Hsp_query-to>411</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>160</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>43</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>MLYLVGLGLGDAKDITVKGLEIVRQCRTVYLEAYTSILSV----------GKEALM--------DTQRILQEARDADVALLVVGDPFGWTRRLSVV-------------------------PLQLYNFGETVSVVFWTDSWRPESFYDKIARNREMGFHT</Hsp_qseq>
      <Hsp_hseq>MLYLIGLGLSYKSDITVRGLEAIKKCSRVYLEHYTSILMAASQEELESYYGKEIILADRELVETGSKQILNNADKEDVAFLVVGDPFGATTHTDLVLRAKREAIPVEIIHNASVMNAVGACGLQLYNFGQTVSMVFFTDNWRPDSWYDKIWENRKIGLHT</Hsp_hseq>
      <Hsp_midline>MLYL+GLGL    DITV+GLE +++C  VYLE YTSIL            GKE ++         +++IL  A   DVA LVVGDPFG T    +V                          LQLYNFG+TVS+VF+TD+WRP+S+YDKI  NR++G HT</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>84</Statistics_hsp-len>
      <Statistics_eff-space>257203703</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0043849-RA transcript Note:&quot;Protein of unknown function&quot; offset:72 AED:1.00 eAED:1.00 QI:72|0|0|0|0.2|0.33|6|0|145</Iteration_query-def>
  <Iteration_query-len>510</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>83</Statistics_hsp-len>
      <Statistics_eff-space>205865229</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

