<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0029473-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0.12|0.28|0.5|8|209|329</BlastOutput_query-def>
  <BlastOutput_query-len>1199</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0029473-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0.12|0.28|0.5|8|209|329</Iteration_query-def>
  <Iteration_query-len>1199</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>92</Statistics_hsp-len>
      <Statistics_eff-space>708208169</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0046255-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.4|0.5|6|2|197</Iteration_query-def>
  <Iteration_query-len>593</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>85</Statistics_hsp-len>
      <Statistics_eff-space>263543504</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0046256-RA transcript Note:&quot;Similar to FANCA Fanconi anemia group A protein (Homo sapiens)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.14|0.37|8|0|187</Iteration_query-def>
  <Iteration_query-len>564</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>84</Statistics_hsp-len>
      <Statistics_eff-space>245405368</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0046257-RA transcript Note:&quot;Protein of unknown function&quot; offset:651 AED:1.00 eAED:1.00 QI:651|0|0|0|0.25|0.2|5|0|151</Iteration_query-def>
  <Iteration_query-len>1104</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>640830359</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054701-RA transcript Note:&quot;Similar to vat VCP-like ATPase (Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165))&quot; offset:0 AED:0.69 eAED:0.69 QI:0|0|0|0.75|1|1|4|0|751</Iteration_query-def>
  <Iteration_query-len>2256</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDL126C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:236157:238664:-1 gene:YDL126C transcript:YDL126C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC48 description:AAA ATPase; subunit of polyUb-selective segregase complex involved in ERAD, INM-associated degradation (INMAD), mitotic spindle disassembly, macroautophagy, PMN, ribosome-associated degradation, ribophagy, homotypic ER membrane fusion, SCF complex disassembly, cell wall integrity during heat stress, and telomerase regulation; mobilizes membrane-anchored transcription factors by regulated Ub/proteasome-dependent processing (RUP); human ortholog VCP complements a cdc48 mutant [Source:SGD;Acc:S000002284]</Hit_def>
  <Hit_accession>YDL126C</Hit_accession>
  <Hit_len>835</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>140.198</Hsp_bit-score>
      <Hsp_score>352</Hsp_score>
      <Hsp_evalue>9.58603e-35</Hsp_evalue>
      <Hsp_query-from>1612</Hsp_query-from>
      <Hsp_query-to>2097</Hsp_query-to>
      <Hsp_hit-from>211</Hsp_hit-from>
      <Hsp_hit-to>429</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>87</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>63</Hsp_gaps>
      <Hsp_align-len>222</Hsp_align-len>
      <Hsp_qseq>VTYADIGGLGPQLQAIREDIELPLLHPEVFTQLGVCPPRGVILHGSPGTGKTMIARAVAHETRAHFYLINGPEIFNRR-----------------------------------------------GQLLVL-------------AATNRLHAIDPALRRPGRFDRELEVPPPDATGRRAILERLLGRPGLPHVVTGPEVAALARATHAYTGADLTALLKEGG</Hsp_qseq>
      <Hsp_hseq>VGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLADDV---DLEALAAETHGYVGADIASLCSEAA</Hsp_hseq>
      <Hsp_midline>V Y DIGG   Q+  IRE +ELPL HP++F  +G+ PPRGV+++G PGTGKT++ARAVA+ET A F+LINGPE+ ++                                                 QLL L             AATNR ++IDPALRR GRFDRE+++  PDATGR  +L        L   V   ++ ALA  TH Y GAD+ +L  E  </Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>85.1149</Hsp_bit-score>
      <Hsp_score>209</Hsp_score>
      <Hsp_evalue>1.76094e-17</Hsp_evalue>
      <Hsp_query-from>1612</Hsp_query-from>
      <Hsp_query-to>1839</Hsp_query-to>
      <Hsp_hit-from>484</Hsp_hit-from>
      <Hsp_hit-to>559</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>76</Hsp_align-len>
      <Hsp_qseq>VTYADIGGLGPQLQAIREDIELPLLHPEVFTQLGVCPPRGVILHGSPGTGKTMIARAVAHETRAHFYLINGPEIFN</Hsp_qseq>
      <Hsp_hseq>VTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLS</Hsp_hseq>
      <Hsp_midline>VT+ D+GGL    + ++E +E P+LHP+ +T+ G+ P +GV+ +G PGTGKT++A+AVA E  A+F  + GPE+ +</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>4.09825e-11</Hsp_evalue>
      <Hsp_query-from>1834</Hsp_query-from>
      <Hsp_query-to>2133</Hsp_query-to>
      <Hsp_hit-from>621</Hsp_hit-from>
      <Hsp_hit-to>717</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>100</Hsp_align-len>
      <Hsp_qseq>FNRRGQLLVLAATNRLHAIDPALRRPGRFDRELEVPPPDATGRRAILERLLGRPGLPHVVTGPEVAALARATHAYTGADLTALLKEGGGGACTSTVRRER</Hsp_qseq>
      <Hsp_hseq>MNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLE---PGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIEAHR</Hsp_hseq>
      <Hsp_midline> N +  + V+ ATNR   IDPA+ RPGR D+ + VP PD   R +IL   L +  L     G E+ A+A+AT  ++GADL  +++     A   ++   R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YDR394W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1261681:1262967:1 gene:YDR394W transcript:YDR394W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RPT3 description:ATPase of the 19S regulatory particle of the 26S proteasome; one of ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; substrate of N-acetyltransferase B [Source:SGD;Acc:S000002802]</Hit_def>
  <Hit_accession>YDR394W</Hit_accession>
  <Hit_len>428</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>109.383</Hsp_bit-score>
      <Hsp_score>272</Hsp_score>
      <Hsp_evalue>6.1438e-26</Hsp_evalue>
      <Hsp_query-from>1612</Hsp_query-from>
      <Hsp_query-to>2133</Hsp_query-to>
      <Hsp_hit-from>169</Hsp_hit-from>
      <Hsp_hit-to>399</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>75</Hsp_gaps>
      <Hsp_align-len>240</Hsp_align-len>
      <Hsp_qseq>VTYADIGGLGPQLQAIREDIELPLLHPEVFTQLGVCPPRGVILHGSPGTGKTMIARAVAHETRA-----------HFYLINGPEI----------------------------------------------------FNRRGQLLVLAATNRLHAIDPALRRPGRFDRELEVPP-PDATGRRAILERLLGRPGLPHVVTGPE--VAALARATHAYTGADLTALLKEGGGGACTSTVRRER</Hsp_qseq>
      <Hsp_hseq>VTYADVGGLDMQKQEIREAVELPLVQADLYEQIGIDPPRGVLLYGPPGTGKTMLVKAVANSTKAAFIRVNGSEFVHKYLGEGPRMVRDVFRLARENAPSIIFIDEVDSIATKRFDAQTGSDREVQRILIELLTQMDGFDQSTNVKVIMATNRADTLDPALLRPGRLDRKIEFPSLRDRRERRLIFGTIASKMSL-----APEADLDSLIIRNDSLSGAVIAAIMQEAGLRA----VRKNR</Hsp_hseq>
      <Hsp_midline>VTYAD+GGL  Q Q IRE +ELPL+  +++ Q+G+ PPRGV+L+G PGTGKTM+ +AVA+ T+A           H YL  GP +                                                    F++   + V+ ATNR   +DPAL RPGR DR++E P   D   RR I   +  +  L      PE  + +L     + +GA + A+++E G  A    VR+ R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YDL007W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:438047:439360:1 gene:YDL007W transcript:YDL007W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RPT2 description:ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; required for normal peptide hydrolysis by the core 20S particle; N-myristoylation of Rpt2p at Gly2 is involved in regulating the proper intracellular distribution of proteasome activity by controlling the nuclear localization of the 26S proteasome [Source:SGD;Acc:S000002165]</Hit_def>
  <Hit_accession>YDL007W</Hit_accession>
  <Hit_len>437</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>107.071</Hsp_bit-score>
      <Hsp_score>266</Hsp_score>
      <Hsp_evalue>3.88374e-25</Hsp_evalue>
      <Hsp_query-from>1615</Hsp_query-from>
      <Hsp_query-to>2097</Hsp_query-to>
      <Hsp_hit-from>180</Hsp_hit-from>
      <Hsp_hit-to>400</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>66</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>TYADIGGLGPQLQAIREDIELPLLHPEVFTQLGVCPPRGVILHGSPGTGKTMIARAVAHETRAHF-----------YLINGP----EIFN------------------------------RRGQLLVLAATNRLHAID------------------PALRRPGRFDRELEVPPPDATGRRAILERLLGRPGLPHVVTGPEVAALARATHAYTGADLTALLKEGG</Hsp_qseq>
      <Hsp_hseq>SYSDIGGLESQIQEIKESVELPLTHPELYEEMGIKPPKGVILYGAPGTGKTLLAKAVANQTSATFLRIVGSELIQKYLGDGPRLCRQIFKVAGENAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDDRGDVKVIMATNKIETLDPALIRPGRIDRKILFENPDLSTKKKILGIHTSKMNLSEDVN---LETLVTTKDDLSGADIQAMCTEAG</Hsp_hseq>
      <Hsp_midline>+Y+DIGGL  Q+Q I+E +ELPL HPE++ ++G+ PP+GVIL+G+PGTGKT++A+AVA++T A F           YL +GP    +IF                               R  Q  +L   N+L   D                  PAL RPGR DR++    PD + ++ IL     +  L   V    +  L       +GAD+ A+  E G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YLR397C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:912550:914892:-1 gene:YLR397C transcript:YLR397C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AFG2 description:ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex; is essential for pre-60S maturation and release of several preribosome maturation factors; releases Rlp24p from purified pre-60S particles in vitro; target of the ribosomal biosynthesis inhibitor diazaborine; may be involved in degradation of aberrant mRNAs [Source:SGD;Acc:S000004389]</Hit_def>
  <Hit_accession>YLR397C</Hit_accession>
  <Hit_len>780</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>103.99</Hsp_bit-score>
      <Hsp_score>258</Hsp_score>
      <Hsp_evalue>2.09378e-23</Hsp_evalue>
      <Hsp_query-from>1606</Hsp_query-from>
      <Hsp_query-to>2127</Hsp_query-to>
      <Hsp_hit-from>240</Hsp_hit-from>
      <Hsp_hit-to>471</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>66</Hsp_gaps>
      <Hsp_align-len>236</Hsp_align-len>
      <Hsp_qseq>RPVTYADIGGLGPQLQAIREDIELPLLHPEVFTQLGVCPPRGVILHGSPGTGKTMIARAVAHETRAHFYLINGP---------------EIFN--RRGQLLVL-------AATNRLH---------------------------AIDPALRRPGRFD----------RELEVPPPDATGRRAILERLLGRPGLP-HVVTGPEVAALARATHAYTGADLTALLKEGGGGACTSTVRR</Hsp_qseq>
      <Hsp_hseq>EPLSYAAVGGLDKEIESLKSAIEIPLHQPTLFSSFGVSPPRGILLHGPPGTGKTMLLRVVANTSNAHVLTINGPSIVSKYLGETEAALRDIFNEARKYQPSIIFIDEIDSIAPNRANDDSGEVESRVVATLLTLMDGMGAAGKVVVIAATNRPNSVDPALRRPGRFDQEVEIGIPDVDARFDILTKQFSRMSSDRHVLDSEAIKYIASKTHGYVGADLTALCRE----SVMKTIQR</Hsp_hseq>
      <Hsp_midline> P++YA +GGL  ++++++  IE+PL  P +F+  GV PPRG++LHG PGTGKTM+ R VA+ + AH   INGP               +IFN  R+ Q  ++        A NR +                            +  A  RP   D          +E+E+  PD   R  IL +   R     HV+    +  +A  TH Y GADLTAL +E    +   T++R</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>77.411</Hsp_bit-score>
      <Hsp_score>189</Hsp_score>
      <Hsp_evalue>4.31682e-15</Hsp_evalue>
      <Hsp_query-from>1612</Hsp_query-from>
      <Hsp_query-to>2106</Hsp_query-to>
      <Hsp_hit-from>513</Hsp_hit-from>
      <Hsp_hit-to>735</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>62</Hsp_gaps>
      <Hsp_align-len>225</Hsp_align-len>
      <Hsp_qseq>VTYADIGGLGPQLQAIREDIELPLLHPEVFTQLGVCPPRGVILHGSPGTGKTMIARAVAHETRAHFYLINGPEIFN------------------------------------RRGQLLVLAA---TNRLHAID-----------PALRRPGRFD----------RELEVPPPDATGRRAILERLLGRPGLPHVVTGPEVAALARATHAYTGADLTALLKEGGGGA</Hsp_qseq>
      <Hsp_hseq>VYWSDIGGQEELKTKMKEMIQLPLEASETFARLGISAPKGVLLYGPPGCSKTLTAKALATESGINFLAVKGPEIFNKYVGESERAIREIFRKARSAAPSIIFFDEIDALSPDRDGSSTSAANHVLTSLLNEIDGVEELKGVVIVAATNRPDEIDAALLRPGRLDRHIYVGPPDVNARLEILKKCTKKFNTEE--SGVDLHELADRTEGYSGAEVVLLCQEAGLAA</Hsp_hseq>
      <Hsp_midline>V ++DIGG       ++E I+LPL   E F +LG+  P+GV+L+G PG  KT+ A+A+A E+  +F  + GPEIFN                                    R G     A    T+ L+ ID            A  RP   D          R + V PPD   R  IL++   +       +G ++  LA  T  Y+GA++  L +E G  A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YOR259C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:812395:813708:-1 gene:YOR259C transcript:YOR259C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RPT4 description:ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in degradation of ubiquitinated substrates; contributes preferentially to ERAD; required for spindle pole body duplication; mainly nuclear localization [Source:SGD;Acc:S000005785]</Hit_def>
  <Hit_accession>YOR259C</Hit_accession>
  <Hit_len>437</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>92.4337</Hsp_bit-score>
      <Hsp_score>228</Hsp_score>
      <Hsp_evalue>3.05316e-20</Hsp_evalue>
      <Hsp_query-from>1612</Hsp_query-from>
      <Hsp_query-to>2097</Hsp_query-to>
      <Hsp_hit-from>178</Hsp_hit-from>
      <Hsp_hit-to>399</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>68</Hsp_gaps>
      <Hsp_align-len>226</Hsp_align-len>
      <Hsp_qseq>VTYADIGGLGPQLQAIREDIELPLLHPEVFTQLGVCPPRGVILHGSPGTGKT------------------------------------MIARAVAHE---------------------------TRAHFYLINGPEIFNRRGQLLVLAATNRLHAIDPALRRPGRFDRELEVPPPDATGRRAILERLLGRPGLPHVVTGP-EVAALARATHAYTGADLTALLKEGG</Hsp_qseq>
      <Hsp_hseq>ITFDGIGGLTEQIRELREVIELPLKNPEIFQRVGIKPPKGVLLYGPPGTGKTLLAKAVAATIGANFIFSPASGIVDKYIGESARIIREMFAYAKEHEPCIIFMDEVDAIGGRRFSEGTSADREIQRTLMELLTQMDGFDNLGQTKIIMATNRPDTLDPALLRPGRLDRKVEIPLPNEAGRLEIFKIHTAKVK----KTGEFDFEAAVKMSDGFNGADIRNCATEAG</Hsp_hseq>
      <Hsp_midline>+T+  IGGL  Q++ +RE IELPL +PE+F ++G+ PP+GV+L+G PGTGKT                                    M A A  HE                            R    L+   + F+  GQ  ++ ATNR   +DPAL RPGR DR++E+P P+  GR  I +    +       TG  +  A  + +  + GAD+     E G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YKL145W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:174213:175616:1 gene:YKL145W transcript:YKL145W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RPT1 description:ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; required for optimal CDC20 transcription; interacts with Rpn12p and Ubr1p; mutant has aneuploidy tolerance [Source:SGD;Acc:S000001628]</Hit_def>
  <Hit_accession>YKL145W</Hit_accession>
  <Hit_len>467</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>92.0485</Hsp_bit-score>
      <Hsp_score>227</Hsp_score>
      <Hsp_evalue>4.79522e-20</Hsp_evalue>
      <Hsp_query-from>1576</Hsp_query-from>
      <Hsp_query-to>1842</Hsp_query-to>
      <Hsp_hit-from>193</Hsp_hit-from>
      <Hsp_hit-to>282</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>90</Hsp_align-len>
      <Hsp_qseq>PSTTVPXXXXRP-VTYADIGGLGPQLQAIREDIELPLLHPEVFTQLGVCPPRGVILHGSPGTGKTMIARAVAHETRAHFYLINGPEIFNR</Hsp_qseq>
      <Hsp_hseq>PSVTMMTVEEKPDVTYSDVGGCKDQIEKLREVVELPLLSPERFATLGIDPPKGILLYGPPGTGKTLCARAVANRTDATFIRVIGSELVQK</Hsp_hseq>
      <Hsp_midline>PS T+   +++P VTY+D+GG   Q++ +RE +ELPLL PE F  LG+ PP+G++L+G PGTGKT+ ARAVA+ T A F  + G E+  +</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>2.27992e-08</Hsp_evalue>
      <Hsp_query-from>1798</Hsp_query-from>
      <Hsp_query-to>2097</Hsp_query-to>
      <Hsp_hit-from>331</Hsp_hit-from>
      <Hsp_hit-to>427</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>100</Hsp_align-len>
      <Hsp_qseq>RAHFYLINGPEIFNRRGQLLVLAATNRLHAIDPALRRPGRFDRELEVPPPDATGRRAILERLLGRPGLPHVVTGPEVAALARATHAYTGADLTALLKEGG</Hsp_qseq>
      <Hsp_hseq>RTMLELITQLDGFDPRGNIKVMFATNRPNTLDPALLRPGRIDRKVEFSLPDLEGRANIF-RIHSKS--MSVERGIRWELISRLCPNSTGAELRSVCTEAG</Hsp_hseq>
      <Hsp_midline>R    LI   + F+ RG + V+ ATNR + +DPAL RPGR DR++E   PD  GR  I  R+  +     V  G     ++R     TGA+L ++  E G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YGL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:410069:411286:-1 gene:YGL048C transcript:YGL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RPT6 description:ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; bound by ubiquitin-protein ligases Ubr1p and Ufd4p; localized mainly to the nucleus throughout the cell cycle; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003016]</Hit_def>
  <Hit_accession>YGL048C</Hit_accession>
  <Hit_len>405</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.1225</Hsp_bit-score>
      <Hsp_score>222</Hsp_score>
      <Hsp_evalue>1.20315e-19</Hsp_evalue>
      <Hsp_query-from>1615</Hsp_query-from>
      <Hsp_query-to>1842</Hsp_query-to>
      <Hsp_hit-from>146</Hsp_hit-from>
      <Hsp_hit-to>221</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>76</Hsp_align-len>
      <Hsp_qseq>TYADIGGLGPQLQAIREDIELPLLHPEVFTQLGVCPPRGVILHGSPGTGKTMIARAVAHETRAHFYLINGPEIFNR</Hsp_qseq>
      <Hsp_hseq>TYDMVGGLTKQIKEIKEVIELPVKHPELFESLGIAQPKGVILYGPPGTGKTLLARAVAHHTDCKFIRVSGAELVQK</Hsp_hseq>
      <Hsp_midline>TY  +GGL  Q++ I+E IELP+ HPE+F  LG+  P+GVIL+G PGTGKT++ARAVAH T   F  ++G E+  +</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>2.8486e-10</Hsp_evalue>
      <Hsp_query-from>1798</Hsp_query-from>
      <Hsp_query-to>2097</Hsp_query-to>
      <Hsp_hit-from>270</Hsp_hit-from>
      <Hsp_hit-to>366</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>100</Hsp_align-len>
      <Hsp_qseq>RAHFYLINGPEIFNRRGQLLVLAATNRLHAIDPALRRPGRFDRELEVPPPDATGRRAILERLLGRPGLPHVVTGPEVAALARATHAYTGADLTALLKEGG</Hsp_qseq>
      <Hsp_hseq>RTMLELLNQLDGFETSKNIKIIMATNRLDILDPALLRPGRIDRKIEFPPPSVAARAEIL-RIHSRK--MNLTRGINLRKVAEKMNGCSGADVKGVCTEAG</Hsp_hseq>
      <Hsp_midline>R    L+N  + F     + ++ ATNRL  +DPAL RPGR DR++E PPP    R  IL R+  R    ++  G  +  +A   +  +GAD+  +  E G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YGR270W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:1027370:1031509:1 gene:YGR270W transcript:YGR270W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YTA7 description:Protein that localizes to chromatin; has a role in regulation of histone gene expression; has a bromodomain-like region that interacts with the N-terminal tail of histone H3, and an ATPase domain; relocalizes to the cytosol in response to hypoxia; potentially phosphorylated by Cdc28p [Source:SGD;Acc:S000003502]</Hit_def>
  <Hit_accession>YGR270W</Hit_accession>
  <Hit_len>1379</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.1814</Hsp_bit-score>
      <Hsp_score>191</Hsp_score>
      <Hsp_evalue>3.17911e-15</Hsp_evalue>
      <Hsp_query-from>1612</Hsp_query-from>
      <Hsp_query-to>1842</Hsp_query-to>
      <Hsp_hit-from>410</Hsp_hit-from>
      <Hsp_hit-to>491</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>53</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>82</Hsp_align-len>
      <Hsp_qseq>VTYADIGGLGPQLQAIREDIELPLLHPEVFTQLGVCPPRGVILHGSPGTGKTMIARAVA-----HETRAHFYLINGPEIFNR</Hsp_qseq>
      <Hsp_hseq>VNFDDIGGLDNYIDQLKEMVALPLLYPELYQNFNITPPRGVLFHGPPGTGKTLMARALAASCSSDERKITFFMRKGADILSK</Hsp_hseq>
      <Hsp_midline>V + DIGGL   +  ++E + LPLL+PE++    + PPRGV+ HG PGTGKT++ARA+A      E +  F++  G +I ++</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>72.7886</Hsp_bit-score>
      <Hsp_score>177</Hsp_score>
      <Hsp_evalue>1.40467e-13</Hsp_evalue>
      <Hsp_query-from>1837</Hsp_query-from>
      <Hsp_query-to>2097</Hsp_query-to>
      <Hsp_hit-from>550</Hsp_hit-from>
      <Hsp_hit-to>634</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>87</Hsp_align-len>
      <Hsp_qseq>NRRGQLLVLAATNRLHAIDPALRRPGRFDRELEVPPPDATGRRAILERLLGRPGLPHVVTGPEVAALARATHAYTGADLTALLKEGG</Hsp_qseq>
      <Hsp_hseq>DNRGQVIVIGATNRPDAVDPALRRPGRFDREFYFPLPDVKARFKILQIQTRKWSSP--LSTNFIDKLAFLTKGYGGADLRSLCTEAA</Hsp_hseq>
      <Hsp_midline>+ RGQ++V+ ATNR  A+DPALRRPGRFDRE   P PD   R  IL+    +   P  ++   +  LA  T  Y GADL +L  E  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YLL034C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:70633:73146:-1 gene:YLL034C transcript:YLL034C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIX7 description:Putative ATPase of the AAA family; required for export of pre-ribosomal large subunits from the nucleus; distributed between the nucleolus, nucleoplasm, and nuclear periphery depending on growth conditions [Source:SGD;Acc:S000003957]</Hit_def>
  <Hit_accession>YLL034C</Hit_accession>
  <Hit_len>837</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>9.42504e-14</Hsp_evalue>
      <Hsp_query-from>1612</Hsp_query-from>
      <Hsp_query-to>1842</Hsp_query-to>
      <Hsp_hit-from>530</Hsp_hit-from>
      <Hsp_hit-to>606</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>81</Hsp_align-len>
      <Hsp_qseq>VTYADIGGLGPQLQAIREDIEL----PLLHPEVFTQLGVCPPRGVILHGSPGTGKTMIARAVAHETRAHFYLINGPEIFNR</Hsp_qseq>
      <Hsp_hseq>VTWANVGAL----QRVRLELNMAIVQPIKRPELYEKVGISAPGGVLLWGPPGCGKTLLAKAVANESRANFISIKGPELLNK</Hsp_hseq>
      <Hsp_midline>VT+A++G L    Q +R ++ +    P+  PE++ ++G+  P GV+L G PG GKT++A+AVA+E+RA+F  I GPE+ N+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>6.83285e-13</Hsp_evalue>
      <Hsp_query-from>1627</Hsp_query-from>
      <Hsp_query-to>1833</Hsp_query-to>
      <Hsp_hit-from>207</Hsp_hit-from>
      <Hsp_hit-to>275</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>69</Hsp_align-len>
      <Hsp_qseq>IGGLGPQLQAIREDIELPLLHPEVFTQLGVCPPRGVILHGSPGTGKTMIARAVAHETRAHFYLINGPEI</Hsp_qseq>
      <Hsp_hseq>LGGMDDVVAQLMELIGLPILHPEIFLSTGVEPPRGVLLHGPPGCGKTSIANALAGELQVPFISISAPSV</Hsp_hseq>
      <Hsp_midline>+GG+   +  + E I LP+LHPE+F   GV PPRGV+LHG PG GKT IA A+A E +  F  I+ P +</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>3.52849e-08</Hsp_evalue>
      <Hsp_query-from>1852</Hsp_query-from>
      <Hsp_query-to>2106</Hsp_query-to>
      <Hsp_hit-from>347</Hsp_hit-from>
      <Hsp_hit-to>428</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>85</Hsp_align-len>
      <Hsp_qseq>LLVLAATNRLHAIDPALRRPGRFDRELEVPPPDATGRRAILERLLGRPGLPHVVTGPEVAALARATHAYTGADLTALLKEGGGGA</Hsp_qseq>
      <Hsp_hseq>VIIIGATNRPDSLDAALRRAGRFDREICLNVPNEVSRLHILKKMSDNLKIDGAI---DFAKLAKLTPGFVGADLKALVTAAGTCA</Hsp_hseq>
      <Hsp_midline>++++ ATNR  ++D ALRR GRFDRE+ +  P+   R  IL+++     +   +   + A LA+ T  + GADL AL+   G  A</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>4</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>3.82537e-07</Hsp_evalue>
      <Hsp_query-from>1837</Hsp_query-from>
      <Hsp_query-to>2097</Hsp_query-to>
      <Hsp_hit-from>666</Hsp_hit-from>
      <Hsp_hit-to>752</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>89</Hsp_align-len>
      <Hsp_qseq>NRRGQLLVLAATNRLHAIDPALRRPGRFDRELEVPPPDATGRRAILERLLGRPGLPHVVTGPEVAALARAT--HAYTGADLTALLKEGG</Hsp_qseq>
      <Hsp_hseq>DRRG-IFVIGATNRPDMIDPAMLRPGRLDKSLFIELPNTEEKLDIIKTLTKSHGTP-LSSDVDFEEIIRNEKCNNFSGADLAALVRESS</Hsp_hseq>
      <Hsp_midline>+RRG + V+ ATNR   IDPA+ RPGR D+ L +  P+   +  I++ L    G P + +  +   + R    + ++GADL AL++E  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YOR117W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:545029:546333:1 gene:YOR117W transcript:YOR117W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RPT5 description:ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; recruited to the GAL1-10 promoter region upon induction of transcription; similar to human TBP1 [Source:SGD;Acc:S000005643]</Hit_def>
  <Hit_accession>YOR117W</Hit_accession>
  <Hit_len>434</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>1.44204e-13</Hsp_evalue>
      <Hsp_query-from>1615</Hsp_query-from>
      <Hsp_query-to>1833</Hsp_query-to>
      <Hsp_hit-from>179</Hsp_hit-from>
      <Hsp_hit-to>251</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>73</Hsp_align-len>
      <Hsp_qseq>TYADIGGLGPQLQAIREDIELPLLHPEVFTQLGVCPPRGVILHGSPGTGKTMIARAVAHETRAHFYLINGPEI</Hsp_qseq>
      <Hsp_hseq>TYSDVGGLDKQIEELVEAIVLPMKRADKFKDMGIRAPKGALMYGPPGTGKTLLARACAAQTNATFLKLAAPQL</Hsp_hseq>
      <Hsp_midline>TY+D+GGL  Q++ + E I LP+   + F  +G+  P+G +++G PGTGKT++ARA A +T A F  +  P++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YNL329C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:19541:22633:-1 gene:YNL329C transcript:YNL329C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PEX6 description:AAA-peroxin; heterodimerizes with AAA-peroxin Pex1p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol; mutations in human PEX6 can lead to severe peroxisomal disorders and early death [Source:SGD;Acc:S000005273]</Hit_def>
  <Hit_accession>YNL329C</Hit_accession>
  <Hit_len>1030</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>1.27182e-12</Hsp_evalue>
      <Hsp_query-from>1612</Hsp_query-from>
      <Hsp_query-to>1839</Hsp_query-to>
      <Hsp_hit-from>729</Hsp_hit-from>
      <Hsp_hit-to>803</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>76</Hsp_align-len>
      <Hsp_qseq>VTYADIGGLGPQLQAIREDIELPLLHPEVFTQLGVCPPRGVILHGSPGTGKTMIARAVAHETRAHFYLINGPEIFN</Hsp_qseq>
      <Hsp_hseq>VTWDDIGGIDFVKGEILDTIDMPLKHPELFTS-GMKKRSGILFYGPPGTGKTLMAKAIATNFSLNFFSVKGPELLN</Hsp_hseq>
      <Hsp_midline>VT+ DIGG+      I + I++PL HPE+FT  G+    G++ +G PGTGKT++A+A+A     +F+ + GPE+ N</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>9.66907e-08</Hsp_evalue>
      <Hsp_query-from>1852</Hsp_query-from>
      <Hsp_query-to>2151</Hsp_query-to>
      <Hsp_hit-from>871</Hsp_hit-from>
      <Hsp_hit-to>969</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>101</Hsp_align-len>
      <Hsp_qseq>LLVLAATNRLHAIDPALRRPGRFDRELEVPPPDA-TGRRAILERLLGRPGLPHVVTGPEVAALARATHAYTGADLTALLKEGGGGACTSTVRRERASVGAH</Hsp_qseq>
      <Hsp_hseq>VFVIGATNRPDLLDEALLRPGRFDKLLYLGIPDTDTKQLNILEALTRKFVLDNDVKLIELAKL--CPFNYTGADFYALCSDAMLNAMSRIARMVEKKVSQH</Hsp_hseq>
      <Hsp_midline>+ V+ ATNR   +D AL RPGRFD+ L +  PD  T +  ILE L  +  L + V   E+A L      YTGAD  AL  +    A +   R     V  H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YGR028W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:542203:543291:1 gene:YGR028W transcript:YGR028W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MSP1 description:Highly-conserved N-terminally anchored AAA-ATPase; distributed in the mitochondrial outer membrane and peroxisomes; involved in mitochondrial protein sorting; functions as an extraction engine in local organelle surveillance to remove and initiate degradation of mistargeted proteins, ensuring fidelity of organelle-specific localization of tail-anchored proteins; contains an N-terminal transmembrane domain and C-terminal cytoplasmic ATPase domain [Source:SGD;Acc:S000003260]</Hit_def>
  <Hit_accession>YGR028W</Hit_accession>
  <Hit_len>362</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>1.57631e-12</Hsp_evalue>
      <Hsp_query-from>1612</Hsp_query-from>
      <Hsp_query-to>1842</Hsp_query-to>
      <Hsp_hit-from>88</Hsp_hit-from>
      <Hsp_hit-to>165</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>78</Hsp_align-len>
      <Hsp_qseq>VTYADIGGLGPQLQAIREDIELPLLHPEVFTQLGVCP-PRGVILHGSPGTGKTMIARAVAHETRAHFYLINGPEIFNR</Hsp_qseq>
      <Hsp_hseq>ITFQDIGGLDPLISDLHESVIYPLMMPEVYSNSPLLQAPSGVLLYGPPGCGKTMLAKALAKESGANFISIRMSSIMDK</Hsp_hseq>
      <Hsp_midline>+T+ DIGGL P +  + E +  PL+ PEV++   +   P GV+L+G PG GKTM+A+A+A E+ A+F  I    I ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YBR080C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:398614:400890:-1 gene:YBR080C transcript:YBR080C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SEC18 description:AAA ATPase and SNARE disassembly chaperone; required for vesicular transport between ER and Golgi, the &apos;priming&apos; step in homotypic vacuole fusion, autophagy, and protein secretion; releases Sec17p from SNAP complexes; has similarity to mammalian N-ethylmaleimide-sensitive factor (NSF) [Source:SGD;Acc:S000000284]</Hit_def>
  <Hit_accession>YBR080C</Hit_accession>
  <Hit_len>758</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>9.91866e-12</Hsp_evalue>
      <Hsp_query-from>1627</Hsp_query-from>
      <Hsp_query-to>2124</Hsp_query-to>
      <Hsp_hit-from>241</Hsp_hit-from>
      <Hsp_hit-to>479</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>73</Hsp_gaps>
      <Hsp_align-len>239</Hsp_align-len>
      <Hsp_qseq>IGGLGPQLQAI-REDIELPLLHPEVFTQLGVCPPRGVILHGSPGTGKTMIA-------------------------------------------RAVAHETRAHFYLINGPE-IFNRRG---------------------------QLLVLAATNRLHAIDPALRRPGRFDRELEVPPPDATGRRAILERLLGRPGLPHVVTGP-EVAALARATHAYTGADLTALLKEGGGGACTSTVR</Hsp_qseq>
      <Hsp_hseq>VGGLDKEFTKIFRRAFASRIFPPSVIEKLGISHVKGLLLYGPPGTGKTLIARKIGTMLNAKEPKIVNGPEILSKYVGSSEENIRNLFKDAEAEYRAKGEESSLHIIIFDELDSVFKQRGSRGDGTGVGDNVVNQLLAKMDGVDQLNNILVIGMTNRKDLIDSALLRPGRFEVQVEIHLPDEKGRLQIFDIQTKKMRENNMMSDDVNLAELAALTKNFSGAEIEGLVKSASSFAINKTVN</Hsp_hseq>
      <Hsp_midline>+GGL  +   I R      +  P V  +LG+   +G++L+G PGTGKT+IA                                           RA   E+  H  + +  + +F +RG                            +LV+  TNR   ID AL RPGRF+ ++E+  PD  GR  I +    +    ++++    +A LA  T  ++GA++  L+K     A   TV </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YPR173C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:886524:887837:-1 gene:YPR173C transcript:YPR173C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VPS4 description:AAA-ATPase involved in multivesicular body (MVB) protein sorting; ATP-bound Vps4p localizes to endosomes and catalyzes ESCRT-III disassembly and membrane release; ATPase activity is activated by Vta1p; regulates cellular sterol metabolism [Source:SGD;Acc:S000006377]</Hit_def>
  <Hit_accession>YPR173C</Hit_accession>
  <Hit_len>437</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>7.43501e-11</Hsp_evalue>
      <Hsp_query-from>1612</Hsp_query-from>
      <Hsp_query-to>2091</Hsp_query-to>
      <Hsp_hit-from>130</Hsp_hit-from>
      <Hsp_hit-to>345</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>66</Hsp_gaps>
      <Hsp_align-len>221</Hsp_align-len>
      <Hsp_qseq>VTYADIGGLGPQLQAIREDIELPLLHPEVFTQLGVCPPRGVILHGSPGTGKTMIARAVAHETRAHFYLINGPEIFNRR--------GQLLVLAATNR-----LHAID------------------------------------------------PALRRPGRFDRELEVPPPDATGRRAILERLLGRPGLPHVVTGPEVAALARATHAYTGADLTALLKE</Hsp_qseq>
      <Hsp_hseq>VKWEDVAGLEGAKEALKEAVILPVKFPHLF-KGNRKPTSGILLYGPPGTGKSYLAKAVATEANSTFFSVSSSDLVSKWMGESEKLVKQLFAMARENKPSIIFIDEVDALTGTRGEGESEASRRIKTELLVQMNGVGNDSQGVLVLGATNIPWQLDSAIRR--RFERRIYIPLPDLAARTTMFEINVG--DTPCVLTKEDYRTLGAMTEGYSGSDIAVVVKD</Hsp_hseq>
      <Hsp_midline>V + D+ GL    +A++E + LP+  P +F +    P  G++L+G PGTGK+ +A+AVA E  + F+ ++  ++ ++          QL  +A  N+     +  +D                                                 A+RR  RF+R + +P PD   R  + E  +G    P V+T  +   L   T  Y+G+D+  ++K+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YPL074W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:415763:418027:1 gene:YPL074W transcript:YPL074W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YTA6 description:Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family; localized to the cortex of mother cells but not to daughter cells; relocalizes from cytoplasm to plasma membrane foci upon DNA replication stress [Source:SGD;Acc:S000005995]</Hit_def>
  <Hit_accession>YPL074W</Hit_accession>
  <Hit_len>754</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>1.66249e-10</Hsp_evalue>
      <Hsp_query-from>1612</Hsp_query-from>
      <Hsp_query-to>1842</Hsp_query-to>
      <Hsp_hit-from>468</Hsp_hit-from>
      <Hsp_hit-to>543</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>77</Hsp_align-len>
      <Hsp_qseq>VTYADIGGLGPQLQAIREDIELPLLHPEVFTQLGVCPPRGVILHGSPGTGKTMIARAVAHETRAHFYLINGPEIFNR</Hsp_qseq>
      <Hsp_hseq>VYWEDIAGLRNAKNSLKEAVVYPFLRPDLFKGLR-EPVRGMLLFGPPGTGKTMIAKAVATESNSTFFSVSASSLLSK</Hsp_hseq>
      <Hsp_midline>V + DI GL     +++E +  P L P++F  L   P RG++L G PGTGKTMIA+AVA E+ + F+ ++   + ++</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>8.39878e-07</Hsp_evalue>
      <Hsp_query-from>1846</Hsp_query-from>
      <Hsp_query-to>2097</Hsp_query-to>
      <Hsp_hit-from>617</Hsp_hit-from>
      <Hsp_hit-to>696</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>GQLLVLAATNRLHAIDPALRRPGRFDRELEVPPPDATGRRAILERLLGRPGLPHVVTGPEVAALARATHAYTGADLTALLKEGG</Hsp_qseq>
      <Hsp_hseq>SRVLVLGATNLPWAIDDAARR--RFSRKLYIPLPDYETRLYHLKRLMAKQ--KNSLQDLDYELITEMTEGFSGSDLTSLAKEAA</Hsp_hseq>
      <Hsp_midline> ++LVL ATN   AID A RR  RF R+L +P PD   R   L+RL+ +    + +   +   +   T  ++G+DLT+L KE  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YER047C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:243810:246503:-1 gene:YER047C transcript:YER047C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAP1 description:Putative ATPase of the AAA family; interacts with the Sin1p transcriptional repressor in the two-hybrid system [Source:SGD;Acc:S000000849]</Hit_def>
  <Hit_accession>YER047C</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>1.37008e-09</Hsp_evalue>
      <Hsp_query-from>1612</Hsp_query-from>
      <Hsp_query-to>1842</Hsp_query-to>
      <Hsp_hit-from>602</Hsp_hit-from>
      <Hsp_hit-to>677</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>77</Hsp_align-len>
      <Hsp_qseq>VTYADIGGLGPQLQAIREDIELPLLHPEVFTQLGVCPPRGVILHGSPGTGKTMIARAVAHETRAHFYLINGPEIFNR</Hsp_qseq>
      <Hsp_hseq>VHWDDIAGLESAKYSLKEAVVYPFLRPDLFRGLR-EPVRGMLLFGPPGTGKTMLARAVATESHSTFFSISASSLTSK</Hsp_hseq>
      <Hsp_midline>V + DI GL     +++E +  P L P++F  L   P RG++L G PGTGKTM+ARAVA E+ + F+ I+   + ++</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>1.84258e-07</Hsp_evalue>
      <Hsp_query-from>1819</Hsp_query-from>
      <Hsp_query-to>2103</Hsp_query-to>
      <Hsp_hit-from>754</Hsp_hit-from>
      <Hsp_hit-to>841</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>95</Hsp_align-len>
      <Hsp_qseq>NGPEIFNRRGQLLVLAATNRLHAIDPALRRPGRFDRELEVPPPDATGRRAILERLLGRPGLPHVVTGPEVAALARATHAYTGADLTALLKEGGGG</Hsp_qseq>
      <Hsp_hseq>NGDEDDTR---VLVLAATNLPWSIDEAARR--RFVRRQYIPLPEDQTRHVQFKKLLSHQK--HTLTESDFDELVKITEGYSGSDITSLAKDAAMG</Hsp_hseq>
      <Hsp_midline>NG E   R   +LVLAATN   +ID A RR  RF R   +P P+   R    ++LL      H +T  +   L + T  Y+G+D+T+L K+   G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YER017C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:189503:191788:-1 gene:YER017C transcript:YER017C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AFG3 description:Mitochondrial inner membrane m-AAA protease component; mediates degradation of misfolded or unassembled proteins; also required for correct assembly of mitochondrial enzyme complexes; involved in cytoplasmic mRNA translation and aging; expression of human homolog AFG3L2 can complement yeast yta12 afg3 double mutant [Source:SGD;Acc:S000000819]</Hit_def>
  <Hit_accession>YER017C</Hit_accession>
  <Hit_len>761</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>3.71222e-09</Hsp_evalue>
      <Hsp_query-from>1834</Hsp_query-from>
      <Hsp_query-to>2073</Hsp_query-to>
      <Hsp_hit-from>423</Hsp_hit-from>
      <Hsp_hit-to>505</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>83</Hsp_align-len>
      <Hsp_qseq>FNRRGQLLVLAATNRLHAIDPALRRPGRFDRELEVPPPDATGRRAILERLLGRPGLPHVVTGPE---VAALARATHAYTGADL</Hsp_qseq>
      <Hsp_hseq>FTTSDQVVVLAGTNRPDVLDNALMRPGRFDRHIQIDSPDVNGRQQIYLVHLKRLNLDPLLTDDMNNLSGKLATLTPGFTGADI</Hsp_hseq>
      <Hsp_midline>F    Q++VLA TNR   +D AL RPGRFDR +++  PD  GR+ I    L R  L  ++T         LA  T  +TGAD+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>1.04547e-07</Hsp_evalue>
      <Hsp_query-from>1612</Hsp_query-from>
      <Hsp_query-to>1833</Hsp_query-to>
      <Hsp_hit-from>285</Hsp_hit-from>
      <Hsp_hit-to>357</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>42</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>74</Hsp_align-len>
      <Hsp_qseq>VTYADIGGLGPQLQAIREDIELPLLHPEVFTQLGVCPPRGVILHGSPGTGKTMIARAVAHETRAHFYLINGPEI</Hsp_qseq>
      <Hsp_hseq>ISFKNVAGCDEAKQEIMEFVHF-LKNPGKYTKLGAKIPRGAILSGPPGTGKTLLAKATAGEANVPFLSVSGSEF</Hsp_hseq>
      <Hsp_midline>+++ ++ G     Q I E +   L +P  +T+LG   PRG IL G PGTGKT++A+A A E    F  ++G E </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YKL197C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:70734:73865:-1 gene:YKL197C transcript:YKL197C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PEX1 description:AAA-peroxin; heterodimerizes with AAA-peroxin Pex6p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol; induced by oleic acid and upregulated during anaerobiosis; mutations in human PEX1 can lead to severe peroxisomal disorders and early death [Source:SGD;Acc:S000001680]</Hit_def>
  <Hit_accession>YKL197C</Hit_accession>
  <Hit_len>1043</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>4.58601e-09</Hsp_evalue>
      <Hsp_query-from>1612</Hsp_query-from>
      <Hsp_query-to>1842</Hsp_query-to>
      <Hsp_hit-from>694</Hsp_hit-from>
      <Hsp_hit-to>770</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>44</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>80</Hsp_align-len>
      <Hsp_qseq>VTYADIGGLGPQLQAIREDIELPLLHPEVFTQLGVCPPR---GVILHGSPGTGKTMIARAVAHETRAHFYLINGPEIFNR</Hsp_qseq>
      <Hsp_hseq>IKWGDIGALANAKDVLLETLEWPTKYEPIFVN---CPLRLRSGILLYGYPGCGKTLLASAVAQQCGLNFISVKGPEILNK</Hsp_hseq>
      <Hsp_midline>+ + DIG L      + E +E P  +  +F     CP R   G++L+G PG GKT++A AVA +   +F  + GPEI N+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YMR089C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:445609:448086:-1 gene:YMR089C transcript:YMR089C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YTA12 description:Mitochondrial inner membrane m-AAA protease component; mediates degradation of misfolded or unassembled proteins; also required for correct assembly of mitochondrial enzyme complexes; overexpression of human AFG3L2 complements respiratory defect of yeast afg3 yta12 double null mutation, but overexpression of disease-associated AFG3L2 variants does not; expression of both human SPG7 (paraplegin) and AFG3L2 complements yeast yta12 afg3 double mutation [Source:SGD;Acc:S000004695]</Hit_def>
  <Hit_accession>YMR089C</Hit_accession>
  <Hit_len>825</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>4.57606e-08</Hsp_evalue>
      <Hsp_query-from>1612</Hsp_query-from>
      <Hsp_query-to>1833</Hsp_query-to>
      <Hsp_hit-from>345</Hsp_hit-from>
      <Hsp_hit-to>417</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>40</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>74</Hsp_align-len>
      <Hsp_qseq>VTYADIGGLGPQLQAIREDIELPLLHPEVFTQLGVCPPRGVILHGSPGTGKTMIARAVAHETRAHFYLINGPEI</Hsp_qseq>
      <Hsp_hseq>IKFKDVAGCDEAKEEIMEFVSF-LKEPSRYEKMGAKIPRGAILSGPPGTGKTLLAKATAGEAGVPFYFVSGSEF</Hsp_hseq>
      <Hsp_midline>+ + D+ G     + I E +   L  P  + ++G   PRG IL G PGTGKT++A+A A E    FY ++G E </Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>2.80894e-06</Hsp_evalue>
      <Hsp_query-from>1852</Hsp_query-from>
      <Hsp_query-to>2091</Hsp_query-to>
      <Hsp_hit-from>488</Hsp_hit-from>
      <Hsp_hit-to>566</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>44</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>LLVLAATNRLHAIDPALRRPGRFDRELEVPPPDATGRRAILERLLGRPGLPHVVTGPEV----AALARATHAYTGADLTALLKE</Hsp_qseq>
      <Hsp_hseq>VVVLAGTNRPDILDKALLRPGRFDRHINIDKPELEGRKAIFA-----VHLHHLKLAGEIFDLKNRLAALTPGFSGADIANVCNE</Hsp_hseq>
      <Hsp_midline>++VLA TNR   +D AL RPGRFDR + +  P+  GR+AI         L H+    E+      LA  T  ++GAD+  +  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YPR024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:610481:612724:1 gene:YPR024W transcript:YPR024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YME1 description:Catalytic subunit of i-AAA protease complex; complex is located in mitochondrial inner membrane; responsible for degradation of unfolded or misfolded mitochondrial gene products; serves as nonconventional translocation motor to pull PNPase into intermembrane space; also has role in intermembrane space protein folding; mutation causes elevated rate of mitochondrial turnover; human homolog YME1L1 can complement yeast null mutant [Source:SGD;Acc:S000006228]</Hit_def>
  <Hit_accession>YPR024W</Hit_accession>
  <Hit_len>747</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>4.93084e-08</Hsp_evalue>
      <Hsp_query-from>1834</Hsp_query-from>
      <Hsp_query-to>2109</Hsp_query-to>
      <Hsp_hit-from>411</Hsp_hit-from>
      <Hsp_hit-to>499</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>92</Hsp_align-len>
      <Hsp_qseq>FNRRGQLLVLAATNRLHAIDPALRRPGRFDRELEVPPPDATGRRAILERLLGRPGLPHVVTGPEVAALARATHAYTGADLTALLKEGGGGAC</Hsp_qseq>
      <Hsp_hseq>FSQTSGIIIIGATNFPEALDKALTRPGRFDKVVNVDLPDVRGRADILKHHMKKITLADNV-DPTI--IARGTPGLSGAELANLVNQAAVYAC</Hsp_hseq>
      <Hsp_midline>F++   ++++ ATN   A+D AL RPGRFD+ + V  PD  GR  IL+  + +  L   V  P +  +AR T   +GA+L  L+ +    AC</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>8.66324e-07</Hsp_evalue>
      <Hsp_query-from>1612</Hsp_query-from>
      <Hsp_query-to>1833</Hsp_query-to>
      <Hsp_hit-from>278</Hsp_hit-from>
      <Hsp_hit-to>350</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>40</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>74</Hsp_align-len>
      <Hsp_qseq>VTYADIGGLGPQLQAIREDIELPLLHPEVFTQLGVCPPRGVILHGSPGTGKTMIARAVAHETRAHFYLINGPEI</Hsp_qseq>
      <Hsp_hseq>VKFDDVCGCDEARAELEEIVDF-LKDPTKYESLGGKLPKGVLLTGPPGTGKTLLARATAGEAGVDFFFMSGSEF</Hsp_hseq>
      <Hsp_midline>V + D+ G       + E ++  L  P  +  LG   P+GV+L G PGTGKT++ARA A E    F+ ++G E </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1489382885</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054702-RA transcript Note:&quot;Similar to DARS2 Aspartate--tRNA ligase, mitochondrial (Homo sapiens)&quot; offset:0 AED:0.22 eAED:0.22 QI:0|0.53|0.71|0.92|0.46|0.5|14|1197|521</Iteration_query-def>
  <Iteration_query-len>2763</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YPL104W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:355700:357676:1 gene:YPL104W transcript:YPL104W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MSD1 description:Mitochondrial aspartyl-tRNA synthetase; required for acylation of aspartyl-tRNA; yeast and bacterial aspartyl-, asparaginyl-, and lysyl-tRNA synthetases contain regions with high sequence similarity, suggesting a common ancestral gene [Source:SGD;Acc:S000006025]</Hit_def>
  <Hit_accession>YPL104W</Hit_accession>
  <Hit_len>658</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>162.155</Hsp_bit-score>
      <Hsp_score>409</Hsp_score>
      <Hsp_evalue>5.58967e-42</Hsp_evalue>
      <Hsp_query-from>838</Hsp_query-from>
      <Hsp_query-to>1539</Hsp_query-to>
      <Hsp_hit-from>406</Hsp_hit-from>
      <Hsp_hit-to>655</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>93</Hsp_identity>
      <Hsp_positive>126</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>251</Hsp_align-len>
      <Hsp_qseq>ADGTWKSSLAKFVSSSEKEEISRLTRAQPGDVVIVAAGN-THSVC---LALGQLRLKCANVLEAKGQVLRNPKDLRFLWVVDFPLFLPREEDSSSGSLE-------------SAHHPFTAPHPDDADLIYARPQDVRGQHYDLVLNGSEIGGGSIRIHDAALQKHVLHDVLKVGPRMGLLGHLLEALESGAPPHGGIALGLDRLVATVVGSASIRDVIAFPKSFRGHDLMSGAPDVISAEELAQYHIKVNS</Hsp_qseq>
      <Hsp_hseq>ANSNWFENFHAIATFENPHLITKFLKLKKGDIVCGCTREPNHSIFENPTPLGRLRQLVLQSEHGKNIYHAVNKDVA-SWIVDFPLFSPVIIEDKSGKKEKLAYPEYEKDRLCSTHHPFTMVKLKDYEKLEKTPEKCLGRHYDLVVNGVELGGGSTRIHDPRLQDYIFEDILKIDNAYELFGHLLNAFDMGTPPHAGFAIGFDRMCAMICETESIRDVIAFPKSITGADLVVKSPSVIPESILEPYNIKYSN</Hsp_hseq>
      <Hsp_midline>A+  W  +     +      I++  + + GD+V        HS+      LG+LR         K       KD+   W+VDFPLF P   +  SG  E             S HHPFT     D + +   P+   G+HYDLV+NG E+GGGS RIHD  LQ ++  D+LK+     L GHLL A + G PPH G A+G DR+ A +  + SIRDVIAFPKS  G DL+  +P VI    L  Y+IK ++</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>121.709</Hsp_bit-score>
      <Hsp_score>304</Hsp_score>
      <Hsp_evalue>6.32447e-29</Hsp_evalue>
      <Hsp_query-from>379</Hsp_query-from>
      <Hsp_query-to>708</Hsp_query-to>
      <Hsp_hit-from>150</Hsp_hit-from>
      <Hsp_hit-to>263</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>115</Hsp_align-len>
      <Hsp_qseq>KYRYLDLRSSQMQHNLRTRSDMVMRMRDYLCNIHGFVDVETPTLFKRTPGGAKEFVVPSREP---GR--FYCLPQSPQQFKQLLMVGGIDRYFQIARCYRDEGSKPDRQPEFTQL</Hsp_qseq>
      <Hsp_hseq>EFRYLQLRNPKYQDFLKKRSSISKEIRNSFNNF-DFTEVETPMLFKATPEGAREFLVPTRTKRSDGKPSFYALDQSPQQYKQLLMASGVNKYYQMARCFRDEDLRADRQPEFTQV</Hsp_hseq>
      <Hsp_midline>++RYL LR+ + Q  L+ RS +   +R+   N   F +VETP LFK TP GA+EF+VP+R     G+  FY L QSPQQ+KQLLM  G+++Y+Q+ARC+RDE  + DRQPEFTQ+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YLL018C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:109902:111575:-1 gene:YLL018C transcript:YLL018C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DPS1 description:Aspartyl-tRNA synthetase, primarily cytoplasmic; homodimeric enzyme that catalyzes the specific aspartylation of tRNA(Asp); class II aminoacyl tRNA synthetase; binding to its own mRNA may confer autoregulation; shares five highly conserved amino acids with human that when mutated cause leukoencephalopathy characterized by hypomyelination with brain stem and spinal cord involvement and leg spasticity (HBSL) [Source:SGD;Acc:S000003941]</Hit_def>
  <Hit_accession>YLL018C</Hit_accession>
  <Hit_len>557</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.8702</Hsp_bit-score>
      <Hsp_score>185</Hsp_score>
      <Hsp_evalue>1.25729e-14</Hsp_evalue>
      <Hsp_query-from>373</Hsp_query-from>
      <Hsp_query-to>1452</Hsp_query-to>
      <Hsp_hit-from>231</Hsp_hit-from>
      <Hsp_hit-to>550</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>103</Hsp_identity>
      <Hsp_positive>150</Hsp_positive>
      <Hsp_gaps>72</Hsp_gaps>
      <Hsp_align-len>376</Hsp_align-len>
      <Hsp_qseq>RMKYRYLDLRSSQMQHNLRTRSDMVMRMRDYLCNIHGFVDVETPTLF-KRTPGGAKEFVVPSREPGRFYCLPQSPQQFKQLLMVGGIDRYFQIARCYRDEGSKPDRQ-PEFTQL-------VNISEALR--STQISFLQAALAGKECSARALRVPGGSRVNVIAVNADGTWKSSLAKFVSSSEKEEISRLTRA--QPGDVVIVAAGNTHSVCLALGQLRLKCANVLEAKGQVLRNPKDLRFLWVVDFPLFLPREEDSSSGSLESAHHPFTAPHPDDADLIYARPQDVRGQHYDLVLNGSEIGGGSIRIHDAALQKHVLHDVLK---VGPRMGLLGHLLEALESGAPPHGGIALGLDRLVATVVGSASIRDVIAFPK</Hsp_qseq>
      <Hsp_hseq>RLDYRVIDLRTVTNQAIFRIQAGVCELFREYLAT-KKFTEVHTPKLLGAPSEGGSSVFEV-TYFKGKAY-LAQSPQFNKQQLIVADFERVYEIGPVFRAENSNTHRHMTEFTGLDMEMAFEEHYHEVLDTLSELFVFIFSELPKRFAHEIEL-VRKQYPVEEFKLPKDG-------KMVRLTYKEGIEMLRAAGKEIGDFEDLSTENEKFL------------------GKLVRDKYDTDFYILDKFPLEI---------------RPFYT-MPDPANPKYS-------NSYDFFMRGEEILSGAQRIHDHAL----LQERMKAHGLSPEDPGLKDYCDGFSYGCPPHAGGGIGLERVVMFYLDLKNIRRASLFPR</Hsp_hseq>
      <Hsp_midline>R+ YR +DLR+   Q   R ++ +    R+YL     F +V TP L    + GG+  F V +   G+ Y L QSPQ  KQ L+V   +R ++I   +R E S   R   EFT L        +  E L   S    F+ + L  +      L V     V    +  DG       K V  + KE I  L  A  + GD   ++  N   +                  G+++R+  D  F  +  FPL +                PF    PD A+  Y+         YD  + G EI  G+ RIHD AL    L + +K   + P    L    +    G PPH G  +GL+R+V   +   +IR    FP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YDR037W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:525440:527215:1 gene:YDR037W transcript:YDR037W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KRS1 description:Lysyl-tRNA synthetase [Source:SGD;Acc:S000002444]</Hit_def>
  <Hit_accession>YDR037W</Hit_accession>
  <Hit_len>591</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>1.8049e-09</Hsp_evalue>
      <Hsp_query-from>358</Hsp_query-from>
      <Hsp_query-to>702</Hsp_query-to>
      <Hsp_hit-from>224</Hsp_hit-from>
      <Hsp_hit-to>339</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>118</Hsp_align-len>
      <Hsp_qseq>KSEALRMKYRYLDLRSSQMQHN-LRTRSDMVMRMRDYLCNIHGFVDVETPTLFKRTPGGA--KEFVVPSREPGRFYCLPQSPQQFKQLLMVGGIDRYFQIARCYRDEGSKPDRQPEFT</Hsp_qseq>
      <Hsp_hseq>KDQETRYRKRYLDLIMNKDARNRFITRSEIIRYIRRFL-DQRKFIEVETP-MMNVIAGGATAKPFITHHNDLDMDMYMRIAPELFLKQLVVGGLDRVYEIGRQFRNEGIDMTHNPEFT</Hsp_hseq>
      <Hsp_midline>K +  R + RYLDL  ++   N   TRS+++  +R +L +   F++VETP +     GGA  K F+    +      +  +P+ F + L+VGG+DR ++I R +R+EG      PEFT</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>1858268274</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054704-RA transcript Note:&quot;Similar to Imp3 U3 small nucleolar ribonucleoprotein protein IMP3 (Mus musculus)&quot; offset:0 AED:0.20 eAED:0.20 QI:0|1|0.8|1|0.5|0.8|5|0|139</Iteration_query-def>
  <Iteration_query-len>420</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YHR148W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:393534:394085:1 gene:YHR148W transcript:YHR148W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IMP3 description:Component of the SSU processome; SSU processome is required for pre-18S rRNA processing, essential protein that interacts with Mpp10p and mediates interactions of Imp4p and Mpp10p with U3 snoRNA [Source:SGD;Acc:S000001191]</Hit_def>
  <Hit_accession>YHR148W</Hit_accession>
  <Hit_len>183</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>5.36237e-13</Hsp_evalue>
      <Hsp_query-from>16</Hsp_query-from>
      <Hsp_query-to>153</Hsp_query-to>
      <Hsp_hit-from>132</Hsp_hit-from>
      <Hsp_hit-to>177</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>25</Hsp_identity>
      <Hsp_positive>37</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>46</Hsp_align-len>
      <Hsp_qseq>ERSDVRVGTEVVMDPAFLVTRSMEDFVTWVDSSKIRRHLMDYNEEV</Hsp_qseq>
      <Hsp_hseq>EQGHVRVGPNLINDPAYLVTRNMEDYVTWVDNSKIKKTLLRYRNQI</Hsp_hseq>
      <Hsp_midline>E+  VRVG  ++ DPA+LVTR+MED+VTWVD+SKI++ L+ Y  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>80</Statistics_hsp-len>
      <Statistics_eff-space>143164020</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054705-RA transcript Note:&quot;Similar to Imp3 U3 small nucleolar ribonucleoprotein protein IMP3 (Mus musculus)&quot; offset:373 AED:0.33 eAED:0.33 QI:373|1|0.66|1|1|1|3|0|107</Iteration_query-def>
  <Iteration_query-len>697</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YHR148W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:393534:394085:1 gene:YHR148W transcript:YHR148W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IMP3 description:Component of the SSU processome; SSU processome is required for pre-18S rRNA processing, essential protein that interacts with Mpp10p and mediates interactions of Imp4p and Mpp10p with U3 snoRNA [Source:SGD;Acc:S000001191]</Hit_def>
  <Hit_accession>YHR148W</Hit_accession>
  <Hit_len>183</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>116.316</Hsp_bit-score>
      <Hsp_score>290</Hsp_score>
      <Hsp_evalue>4.25579e-33</Hsp_evalue>
      <Hsp_query-from>374</Hsp_query-from>
      <Hsp_query-to>694</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>108</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>108</Hsp_align-len>
      <Hsp_qseq>MVRKLRFHEQKLLKKVDFISWEADADRKELRALRRFHIQRRDDYTKYNKLSRDVRTLAGKLKELDPADPFRSEGTNRLLDKLYAMGIIPTRQGLQLCDN-VSASSFCR</Hsp_qseq>
      <Hsp_hseq>MVRKLKHHEQKLLKKVDFLEWKQDQGHRDTQVMRTYHIQNREDYHKYNRICGDIRRLANKLSLLPPTDPFRRKHEQLLLDKLYAMGVLTTKSKISDLENKVTVSAICR</Hsp_hseq>
      <Hsp_midline>MVRKL+ HEQKLLKKVDF+ W+ D   ++ + +R +HIQ R+DY KYN++  D+R LA KL  L P DPFR +    LLDKLYAMG++ T+  +   +N V+ S+ CR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>87</Statistics_hsp-len>
      <Statistics_eff-space>339280715</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054708-RA transcript Note:&quot;Similar to Sec22b Vesicle-trafficking protein SEC22b (Rattus norvegicus)&quot; offset:0 AED:0.26 eAED:0.26 QI:0|0|0.33|1|1|1|3|679|131</Iteration_query-def>
  <Iteration_query-len>1075</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YLR268W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:680200:680844:1 gene:YLR268W transcript:YLR268W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SEC22 description:R-SNARE protein; assembles into SNARE complex with Bet1p, Bos1p and Sed5p; cycles between the ER and Golgi complex; involved in anterograde and retrograde transport between the ER and Golgi; synaptobrevin homolog [Source:SGD;Acc:S000004258]</Hit_def>
  <Hit_accession>YLR268W</Hit_accession>
  <Hit_len>214</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.3654</Hsp_bit-score>
      <Hsp_score>111</Hsp_score>
      <Hsp_evalue>7.41534e-07</Hsp_evalue>
      <Hsp_query-from>31</Hsp_query-from>
      <Hsp_query-to>393</Hsp_query-to>
      <Hsp_hit-from>26</Hsp_hit-from>
      <Hsp_hit-to>211</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>75</Hsp_gaps>
      <Hsp_align-len>191</Hsp_align-len>
      <Hsp_qseq>NLTEYQTKAKQLFRKLNEQSPSRCTLEAGPM-----------------AAFPKKLAFSYLDDLHTEF-HELYHKKVATVSRPYSFIEF----------------------------------------------ALDTKASNLSSL---SKKYRQDAKYLN---MRSTYAKVAAVAVFSIMFILYVRFWWL</Hsp_qseq>
      <Hsp_hseq>SLFEQKQKVKIVVSRLTPQSATEATLESGSFEIHYLKKSMVYYFVICESGYPRNLAFSYLNDIAQEFEHSFANEYPKPTVRPYQFVNFDNFLQMTKKSYSDKKVQDNLDQLNQELVGVKQIMSKNIEDLLYRGDSLDKMSDMSSSLKETSKRYRKSAQKINFDLLISQYAPIVIVAFFFVFL-----FWWI</Hsp_hseq>
      <Hsp_midline>+L E + K K +  +L  QS +  TLE+G                   + +P+ LAFSYL+D+  EF H   ++      RPY F+ F                                              +LD  +   SSL   SK+YR+ A+ +N   + S YA +  VA F +       FWW+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>617695689</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054709-RA transcript Note:&quot;Similar to Fam20b Glycosaminoglycan xylosylkinase (Mus musculus)&quot; offset:0 AED:0.04 eAED:0.04 QI:0|0.8|1|1|1|1|6|2600|364</Iteration_query-def>
  <Iteration_query-len>3695</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2539637710</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054710-RA transcript Note:&quot;Similar to EEF1D Elongation factor 1-delta (Bos taurus)&quot; offset:0 AED:0.19 eAED:0.19 QI:0|0.76|0.92|1|0.53|0.64|14|0|202</Iteration_query-def>
  <Iteration_query-len>609</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YAL003W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:142174:143160:1 gene:YAL003W transcript:YAL003W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:EFB1 description:Translation elongation factor 1 beta; stimulates nucleotide exchange to regenerate EF-1 alpha-GTP for the next elongation cycle; part of the EF-1 complex, which facilitates binding of aminoacyl-tRNA to the ribosomal A site; human homolog EEF1B2 can complement yeast efb1 mutants [Source:SGD;Acc:S000000003]</Hit_def>
  <Hit_accession>YAL003W</Hit_accession>
  <Hit_len>206</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>101.679</Hsp_bit-score>
      <Hsp_score>252</Hsp_score>
      <Hsp_evalue>1.49028e-27</Hsp_evalue>
      <Hsp_query-from>190</Hsp_query-from>
      <Hsp_query-to>528</Hsp_query-to>
      <Hsp_hit-from>83</Hsp_hit-from>
      <Hsp_hit-to>198</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>116</Hsp_align-len>
      <Hsp_qseq>LFGSDEDDGEAE--KLREERVKAYSEKKAKKPVLIAKSSIV-LDVKPWDDETDMAELEAKVRSVSMDGLLWGASKLLPVGYGIKKLQIQCVVEDDKVGTDILEEEITKFEDHWMRT</Hsp_qseq>
      <Hsp_hseq>LFGSDDEEADAEAEKLKAERIAAYNAKKAAKPAKPAAKSIVTLDVKPWDDETNLEEMVANVKAIEMEGLTWGAHQFIPIGFGIKKLQINCVVEDDKVSLDDLQQSIEEDEDHVQST</Hsp_hseq>
      <Hsp_midline>LFGSD+++ +AE  KL+ ER+ AY+ KKA KP   A  SIV LDVKPWDDET++ E+ A V+++ M+GL WGA + +P+G+GIKKLQI CVVEDDKV  D L++ I + EDH   T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>85</Statistics_hsp-len>
      <Statistics_eff-space>277661906</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054692-RA transcript Note:&quot;Similar to STOM Erythrocyte band 7 integral membrane protein (Homo sapiens)&quot; offset:0 AED:0.14 eAED:0.15 QI:0|0|0|1|0.75|0.8|5|0|288</Iteration_query-def>
  <Iteration_query-len>867</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>89</Statistics_hsp-len>
      <Statistics_eff-space>465333400</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0034172-RA transcript Note:&quot;Protein of unknown function&quot; offset:469 AED:0.63 eAED:0.63 QI:469|0.5|0.2|0.6|0|0|5|0|122</Iteration_query-def>
  <Iteration_query-len>835</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>88</Statistics_hsp-len>
      <Statistics_eff-space>443320730</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054687-RA transcript Note:&quot;Similar to KCNMA1 Calcium-activated potassium channel subunit alpha-1 (Oryctolagus cuniculus)&quot; offset:0 AED:0.51 eAED:0.63 QI:0|0.08|0.23|0.69|0.83|0.76|13|871|264</Iteration_query-def>
  <Iteration_query-len>1666</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1052050820</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054688-RA transcript Note:&quot;Similar to KCNMA1 Calcium-activated potassium channel subunit alpha-1 (Homo sapiens)&quot; offset:421 AED:0.40 eAED:0.41 QI:421|0.64|0.73|1|0.71|0.66|15|25|420</Iteration_query-def>
  <Iteration_query-len>1709</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1084069758</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054691-RA transcript Note:&quot;Similar to IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta (Homo sapiens)&quot; offset:0 AED:0.18 eAED:0.18 QI:0|0.11|0.11|0.16|1|1|18|2408|636</Iteration_query-def>
  <Iteration_query-len>4319</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>92.0485</Hsp_bit-score>
      <Hsp_score>227</Hsp_score>
      <Hsp_evalue>3.84743e-19</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>696</Hsp_query-to>
      <Hsp_hit-from>271</Hsp_hit-from>
      <Hsp_hit-to>468</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>203</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEGQKYTVS-------------VDYWSFGTVVFECITGFRPFLPNMQPVQWHSI---VIRKGPHDIVAVEEMNREIKFSSHIPAPHNLNPVLAVQLEH-WLQL</Hsp_qseq>
      <Hsp_hseq>MVMEFVSGGDLMD-FVAAHGAVG--EDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQD-DPVLVKITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGPLKDFRISEEARDF-IDSLLQVDPNNRSTAAKALNHPWIKM</Hsp_hseq>
      <Hsp_midline>+ ME+ SGGDL    +      G  E     +   I  A++Y+H+  I HRDLKP+NI+++Q  D V+ KI D G AK    GS   +F GTL Y+APE+  G+  +VS             VD WS G +V+  +TG  PF  + Q   +  I      +GP     + E  R+    S +    N     A  L H W+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.9669</Hsp_bit-score>
      <Hsp_score>219</Hsp_score>
      <Hsp_evalue>5.01598e-19</Hsp_evalue>
      <Hsp_query-from>136</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>144</Hsp_hit-from>
      <Hsp_hit-to>265</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>132</Hsp_align-len>
      <Hsp_qseq>LLAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIY--DISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>FMVMDYIEGGELFSLLRKSQ-----RFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGH---IKITDFGFAKEVQ--TVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPF</Hsp_hseq>
      <Hsp_midline> + M+Y  GG+L  +L K +     R  + +A  Y  ++  A++YLH + II+RDLKPENI+L +       KI D G+AKE+   ++  +  GT  Y+APE+   + Y  SVD+WS G +++E + G+ PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.5817</Hsp_bit-score>
      <Hsp_score>218</Hsp_score>
      <Hsp_evalue>8.34167e-19</Hsp_evalue>
      <Hsp_query-from>136</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>162</Hsp_hit-from>
      <Hsp_hit-to>283</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>132</Hsp_align-len>
      <Hsp_qseq>LLAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIY--DISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>FMVMDYIEGGELFSLLRKSQ-----RFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGH---IKITDFGFAKYVP--DVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPF</Hsp_hseq>
      <Hsp_midline> + M+Y  GG+L  +L K +     R  + +A  Y  ++  A++YLH+  II+RDLKPENI+L +       KI D G+AK +    +  +  GT  Y+APE+   + Y  SVD+WSFG +++E + G+ PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>89.7373</Hsp_bit-score>
      <Hsp_score>221</Hsp_score>
      <Hsp_evalue>1.35417e-18</Hsp_evalue>
      <Hsp_query-from>124</Hsp_query-from>
      <Hsp_query-to>585</Hsp_query-to>
      <Hsp_hit-from>394</Hsp_hit-from>
      <Hsp_hit-to>564</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>173</Hsp_align-len>
      <Hsp_qseq>RDLPLLAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGY-----------------AKELDQGSLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPFLPNMQPVQWHSIVIR--KGPHD</Hsp_qseq>
      <Hsp_hseq>KDYLYLCMEYCMGGEFFRALQTRKSKC-IAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQS-GHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKFPHD</Hsp_hseq>
      <Hsp_midline>+D   L MEYC GG+  + L   ++ C + E D      ++  A++YLH    I+RDLKPENI+L Q    V+    DL                    K    G    SFVGT +YLAPE+  G  +T +VD+W+ G +++E + G  PF  +     + +I+ +  K PHD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.6557</Hsp_bit-score>
      <Hsp_score>213</Hsp_score>
      <Hsp_evalue>3.51602e-18</Hsp_evalue>
      <Hsp_query-from>136</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>161</Hsp_hit-from>
      <Hsp_hit-to>282</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>132</Hsp_align-len>
      <Hsp_qseq>LLAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIY--DISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>FMIMDYIEGGELFSLLRKSQ-----RFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGH---IKITDFGFAKYVP--DVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPF</Hsp_hseq>
      <Hsp_midline> + M+Y  GG+L  +L K +     R  + +A  Y  ++  A++YLH+  II+RDLKPENI+L +       KI D G+AK +    +  +  GT  Y+APE+   + Y  S+D+WSFG +++E + G+ PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.1965</Hsp_bit-score>
      <Hsp_score>217</Hsp_score>
      <Hsp_evalue>5.20179e-18</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>795</Hsp_query-to>
      <Hsp_hit-from>100</Hsp_hit-from>
      <Hsp_hit-to>337</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>59</Hsp_gaps>
      <Hsp_align-len>258</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDL------RKVLLK---------------PENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQ------------------QDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPFLPNMQPVQWHSIVIRKGPHDIVAVEEMNREIKFSSHIPAPHNLNPVLAVQLEHWLQLMLFWNARQRGGPTVHILNMVTGEVLAYTVRPDD</Hsp_qseq>
      <Hsp_hseq>LIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVVFEMCCGTPPF-----RASNHLELFKK-------IKRANDVITFPSYC----NIEP----ELKELICSLLTFDPAQRIGFEEFFANKVVNEDLSSYELEDD</Hsp_hseq>
      <Hsp_midline>L MEYC+ GDL      RK L++                EN  G+    V++ +  ++ A+++L +  ++HRD+KP+N++L                      +  I KI D G+A+ L   SL  +  G+  Y+APE+   QKY    D WS GTVVFE   G  PF         H  + +K       ++  N  I F S+     N+ P    +L+  +  +L ++  QR G      N V  E L+     DD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.5001</Hsp_bit-score>
      <Hsp_score>210</Hsp_score>
      <Hsp_evalue>5.52271e-18</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>179</Hsp_hit-from>
      <Hsp_hit-to>314</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>150</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLL--KPENCCGMRECDVMA--VIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYA----KELDQGSLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPFLPNMQPVQWHSIV</Hsp_qseq>
      <Hsp_hseq>LLMEYLVNGEMYKLLRLHGPFN-------DILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNN---VIKLTDFGWSIINPPENRRKTVC----GTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIA</Hsp_hseq>
      <Hsp_midline>L MEY   G++ K+L    P N       D++A   IY I+ A+ Y+H   IIHRD+KPENI++       + K+ D G++     E  + ++C    GT+ YL+PE+ E ++Y  ++D W+ G + FE +TG  PF   M+   +  I </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.4261</Hsp_bit-score>
      <Hsp_score>215</Hsp_score>
      <Hsp_evalue>9.8168e-18</Hsp_evalue>
      <Hsp_query-from>127</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>567</Hsp_hit-from>
      <Hsp_hit-to>717</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>153</Hsp_align-len>
      <Hsp_qseq>DLPLLAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDL-------------GYAKEL-------DQGSLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>DYLYLCMEYCMGGEFFRALQTRKTKC-ICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQS-GHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPF</Hsp_hseq>
      <Hsp_midline>D   L MEYC GG+  + L   +  C + E D      +++ A++YLH    I+RDLKPENI+L Q    ++    DL             G A+           G    SFVGT +Y+APE+  G  +T +VD+W+ G +++E + GF PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.6557</Hsp_bit-score>
      <Hsp_score>213</Hsp_score>
      <Hsp_evalue>1.94113e-17</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>200</Hsp_hit-from>
      <Hsp_hit-to>323</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>130</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEGQKYT-VSVDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>MLFEYVSGGQLLDYIIQ---HGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGE---IKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPF</Hsp_hseq>
      <Hsp_midline>+  EY SGG L   +++      ++E         I+ A+QYLH N I+HRDLK ENI++    +    KIID G +   D      +F G+L + APEL + Q YT   VD WSFG V++  + G  PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.1149</Hsp_bit-score>
      <Hsp_score>209</Hsp_score>
      <Hsp_evalue>5.04208e-17</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>221</Hsp_hit-from>
      <Hsp_hit-to>344</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>130</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEGQKYT-VSVDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>MLFEYVSGGQLLDYIIQ---HGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMI---SDSSEIKIIDFGLSNIYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPF</Hsp_hseq>
      <Hsp_midline>+  EY SGG L   +++      +RE         I+ A+ YLH N I+HRDLK ENI++    D    KIID G +   D      +F G+L + APEL +   YT   VD WSFG V+F  + G  PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.8037</Hsp_bit-score>
      <Hsp_score>203</Hsp_score>
      <Hsp_evalue>1.2965e-16</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>582</Hsp_query-to>
      <Hsp_hit-from>290</Hsp_hit-from>
      <Hsp_hit-to>439</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>156</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLR---KVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPF-----LPNMQPVQWHSIVIRKGPH</Hsp_qseq>
      <Hsp_hseq>IAMEYMGGKSLEATYKNLLK--RGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGE---IKLCDFGVSGEA-VNSLAMTFTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRFPFESDKITQNVAPIELLTMILTFSPQ</Hsp_hseq>
      <Hsp_midline>+AMEY  G  L    K LLK      + E  +  +   + + + YLH  ++IHRD+KP+NI+L ++ +    K+ D G + E    SL  +F GT  Y+APE  +GQ Y+V+ D WS G  + E   G  PF       N+ P++  ++++   P </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.1889</Hsp_bit-score>
      <Hsp_score>204</Hsp_score>
      <Hsp_evalue>2.24207e-16</Hsp_evalue>
      <Hsp_query-from>145</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>694</Hsp_hit-from>
      <Hsp_hit-to>845</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>MEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLC-TSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPFLPNMQPVQWHSIVIRKGPHDIVAVEEMNREIK</Hsp_qseq>
      <Hsp_hseq>MEYMEGGSLTDVVTH----CILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGD---IKLTDFGFCAQINELNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPPYL-NETPLRALYLIATNGTPKLKEPENLSSSLK</Hsp_hseq>
      <Hsp_midline>MEY  GG L  V+      C + E  + AV  +    +++LH+  ++HRD+K +NI+L  + D    K+ D G+  ++++ +L  T+ VGT  ++APE+   ++Y   VD WS G ++ E I G  P+L N  P++   ++   G   +   E ++  +K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.0333</Hsp_bit-score>
      <Hsp_score>201</Hsp_score>
      <Hsp_evalue>4.06062e-16</Hsp_evalue>
      <Hsp_query-from>121</Hsp_query-from>
      <Hsp_query-to>600</Hsp_query-to>
      <Hsp_hit-from>485</Hsp_hit-from>
      <Hsp_hit-to>639</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>163</Hsp_align-len>
      <Hsp_qseq>PRDLPLLAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPE-LFEGQKYTVSVDYWSFGTVVFECITGFRPFLPNMQPVQWHSIVIR--KGPHDIVAVE</Hsp_qseq>
      <Hsp_hseq>PTDL-YLVTDYMSGGELFWHLQKEGR---FSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGN---IALCDFGLSK-ADLKDRTNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQE</Hsp_hseq>
      <Hsp_midline>P DL  L  +Y SGG+L   L K        E      I ++  A+++LH N I++RDLKPENI+L    +     + D G +K  D      +F GT +YLAPE L +   YT  VD+WS G ++FE   G+ PF        +  I     K P D+++ E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.2629</Hsp_bit-score>
      <Hsp_score>199</Hsp_score>
      <Hsp_evalue>5.06047e-16</Hsp_evalue>
      <Hsp_query-from>145</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>452</Hsp_hit-from>
      <Hsp_hit-to>613</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>166</Hsp_align-len>
      <Hsp_qseq>MEYCSGGDLRKVL------LKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKEL-DQGSLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPFLPNMQPVQWHSIVIRKGPHDIVAVEEMNREIK</Hsp_qseq>
      <Hsp_hseq>MEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQG---LVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPPYL-NEDPLKALYLIANNGSPKLRHPESVSKQTK</Hsp_hseq>
      <Hsp_midline>MEY  GG L  +L         E+   + E  +  ++ +  Q +++LH  +IIHRD+K +NI+L  Q    + KI D G+  EL ++ S   + VGT  ++APE+   + Y   VD WS G ++ E I G  P+L N  P++   ++   G   +   E ++++ K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.2629</Hsp_bit-score>
      <Hsp_score>199</Hsp_score>
      <Hsp_evalue>7.34493e-16</Hsp_evalue>
      <Hsp_query-from>145</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>257</Hsp_hit-from>
      <Hsp_hit-to>389</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>143</Hsp_align-len>
      <Hsp_qseq>MEYCSGGDLRKVLLK----PENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAK------------ELDQGSLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>LEYAPNGDFLSLMKKYGSLDETCARYYAAQII-------DAIDYLHSNGIIHRDIKPENILLDGE---MKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPF</Hsp_hseq>
      <Hsp_midline>+EY   GD   ++ K     E C       ++        A+ YLH+N IIHRD+KPENI+L  +   +  K+ D G AK            E D  +   SFVGT +Y++PEL          D W+FG ++F+ I G  PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.4925</Hsp_bit-score>
      <Hsp_score>197</Hsp_score>
      <Hsp_evalue>7.57106e-16</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>522</Hsp_query-to>
      <Hsp_hit-from>297</Hsp_hit-from>
      <Hsp_hit-to>421</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>129</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYD-ISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRP</Hsp_qseq>
      <Hsp_hseq>IAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQ---VKLCDFGVSGEA-VNSLATTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANGKFP</Hsp_hseq>
      <Hsp_midline>+AMEY  G  L  +        G     V+  I + + + + YLH  ++IHRD+KP+NI+L +       K+ D G + E    SL T+F GT  Y+APE  +GQ Y+V+ D WS G  + E   G  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.1073</Hsp_bit-score>
      <Hsp_score>196</Hsp_score>
      <Hsp_evalue>9.50973e-16</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>543</Hsp_query-to>
      <Hsp_hit-from>280</Hsp_hit-from>
      <Hsp_hit-to>427</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>151</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQ----------------QQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPFLPNMQP</Hsp_qseq>
      <Hsp_hseq>LVLEKIDDGELFERIVR-KTC--LRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVILYVCLCGFPPFSDQLGP</Hsp_hseq>
      <Hsp_midline>L +E    G+L + +++ + C  +R+ +  A+   +   ++YLH   IIHRD+KPENI+L                 + +  +  KI D G AK   +     +  GT  Y+APE+   + YT  VD WS G +++ C+ GF PF   + P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.8777</Hsp_bit-score>
      <Hsp_score>198</Hsp_score>
      <Hsp_evalue>1.0794e-15</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>621</Hsp_query-to>
      <Hsp_hit-from>638</Hsp_hit-from>
      <Hsp_hit-to>799</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>166</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLLK-PENCCG---MRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKEL-DQGSLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPFLPNMQPVQWHSIVIRKGPHDIVAVEEMNREIK</Hsp_qseq>
      <Hsp_hseq>VVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDT---RARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYL-NEDPLKALYLIATNGTPKLKHPESLSLEIK</Hsp_hseq>
      <Hsp_midline>+ ME+  GG L  ++   P N      + E  +  ++ +  Q +++LH   IIHRD+K +N++L     R   KI D G+   L D+ S   + VGT  ++APE+ + ++Y   +D WS G +  E + G  P+L N  P++   ++   G   +   E ++ EIK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.1814</Hsp_bit-score>
      <Hsp_score>191</Hsp_score>
      <Hsp_evalue>2.57389e-15</Hsp_evalue>
      <Hsp_query-from>124</Hsp_query-from>
      <Hsp_query-to>528</Hsp_query-to>
      <Hsp_hit-from>118</Hsp_hit-from>
      <Hsp_hit-to>250</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>RDLPLLAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELD-QGSLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPFL</Hsp_qseq>
      <Hsp_hseq>KDKFYIVTQLATGGELFDRIL---SRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSPFI</Hsp_hseq>
      <Hsp_midline>+D   +  +  +GG+L   +L   +     E D + +I  I  AV+Y+H+  ++HRDLKPEN++   + +     I D G AK+L  +  L     G+L Y+APE+     +    D WS G + +  + G+ PF+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.8702</Hsp_bit-score>
      <Hsp_score>185</Hsp_score>
      <Hsp_evalue>1.26891e-14</Hsp_evalue>
      <Hsp_query-from>223</Hsp_query-from>
      <Hsp_query-to>639</Hsp_query-to>
      <Hsp_hit-from>121</Hsp_hit-from>
      <Hsp_hit-to>257</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>143</Hsp_align-len>
      <Hsp_qseq>VMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPE-LFEGQKYTVSVDYWSFGTVVFECITGFRPFLPNMQPVQWHSIV---IRKGPHDIVAVEEMNREIKFSSHIP</Hsp_qseq>
      <Hsp_hseq>VQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCD---LKICDFGLARI--QDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEG-KPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENTLKFVTSLP</Hsp_hseq>
      <Hsp_midline>V   +Y I + ++Y+H+  +IHRDLKP NI++ +  D    KI D G A+   Q    T +V T  Y APE +   QKY V VD WS G +  E I G +P  P    V   SI+   +   P D++        +KF + +P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.2554</Hsp_bit-score>
      <Hsp_score>186</Hsp_score>
      <Hsp_evalue>1.38788e-14</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>579</Hsp_query-to>
      <Hsp_hit-from>91</Hsp_hit-from>
      <Hsp_hit-to>234</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>149</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELF--EGQKYTVSVDYWSFGTVVFECITGFRPFLPNMQPVQWHSIVIRKGP</Hsp_qseq>
      <Hsp_hseq>IVMEYCGGGSCSD-LLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEG---MVKLGDFGVSGHIRSTLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPP-LSKYDPMKVMTNLPKRKP</Hsp_hseq>
      <Hsp_midline>+ MEYC GG     LLK     G+ E  V  +I++++  ++YLH  R IHRD+K  NI+L ++    + K+ D G +  +       +FVGT  ++APE+   E   Y    D WS G   +E + G  P L    P++  + + ++ P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.2554</Hsp_bit-score>
      <Hsp_score>186</Hsp_score>
      <Hsp_evalue>2.13992e-14</Hsp_evalue>
      <Hsp_query-from>253</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>454</Hsp_hit-from>
      <Hsp_hit-to>555</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>105</Hsp_align-len>
      <Hsp_qseq>AVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAK-ELDQGSLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPFLPNMQPVQWHSIV</Hsp_qseq>
      <Hsp_hseq>ALDSLHKLDVIYRDLKPENILLDYQGH---IALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKIL</Hsp_hseq>
      <Hsp_midline>A+  LH   +I+RDLKPENI+L  Q       + D G  K  +       +F GT +YLAPE+  GQ YT +VD+W+ G +++E +TG  P+     PV +  I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.8702</Hsp_bit-score>
      <Hsp_score>185</Hsp_score>
      <Hsp_evalue>2.17806e-14</Hsp_evalue>
      <Hsp_query-from>121</Hsp_query-from>
      <Hsp_query-to>531</Hsp_query-to>
      <Hsp_hit-from>297</Hsp_hit-from>
      <Hsp_hit-to>447</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>154</Hsp_align-len>
      <Hsp_qseq>PRDLPL--LAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIY-DISQAVQYLHTNRIIHRDLKPENIVLQQQQDRV-------IY------KIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEGQKYTVSV-DYWSFGTVVFECITGFRPFLP</Hsp_qseq>
      <Hsp_hseq>PRALPPCDMIMSYCPAGDLLAAVMARN---GRLEAWLIQRIFTEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLCKKIENNEMCTARCGSEDYVSPEILMGVPYDGHLSDTWALGVILYSLFEDRLPFDP</Hsp_hseq>
      <Hsp_midline>PR LP   + M YC  GDL   ++      G  E  ++  I+ ++  AV+YLH N IIHRDLK ENI+L+   D +       IY      ++ D G  K+++   +CT+  G+  Y++PE+  G  Y   + D W+ G +++       PF P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.2554</Hsp_bit-score>
      <Hsp_score>186</Hsp_score>
      <Hsp_evalue>2.6921e-14</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>579</Hsp_query-to>
      <Hsp_hit-from>97</Hsp_hit-from>
      <Hsp_hit-to>237</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>149</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSL-CTSFVGTLQYLAPE-LFEGQKYTVSVDYWSFGTVVFECITGFRPFLPNMQPVQWHSIVIRKGP</Hsp_qseq>
      <Hsp_hseq>IIMEHCAGGSLRS-LLRP---GKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGN---VKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYC-DVEALRAMQLIIKSKP</Hsp_hseq>
      <Hsp_midline>+ ME+C+GG LR  LL+P     + E  +  ++ ++  A++ +H + +IHRD+K  N+++  + +    K+ D G A +++Q SL   +  GT  ++APE + EG  Y   VD WS G   +E  TG  P+  +++ ++   ++I+  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.0998</Hsp_bit-score>
      <Hsp_score>183</Hsp_score>
      <Hsp_evalue>5.25338e-14</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>618</Hsp_query-to>
      <Hsp_hit-from>109</Hsp_hit-from>
      <Hsp_hit-to>263</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>161</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEGQKYT-VSVDYWSFGTVVFECITGFRPFLPNMQPVQWHSIVIRKGPHDIVAVEEMNREI</Hsp_qseq>
      <Hsp_hseq>MALEYCPGKELYDHLLSLRRIS-LLECGEL--FAQISGAVYYAHSMHCVHRDLKLENILLDKNGN---AKLTDFGFTRECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDAKVIPDDARDL</Hsp_hseq>
      <Hsp_midline>+A+EYC G +L   LL       + EC  +     IS AV Y H+   +HRDLK ENI+L +  +    K+ D G+ +E    +   +  GT  Y+APEL E + Y    +D WS G +++  ITG+ PF  + +      IV  +  +D   + +  R++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.559</Hsp_bit-score>
      <Hsp_score>179</Hsp_score>
      <Hsp_evalue>9.14366e-14</Hsp_evalue>
      <Hsp_query-from>124</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>108</Hsp_hit-from>
      <Hsp_hit-to>239</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>135</Hsp_align-len>
      <Hsp_qseq>RDLPLLAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQG-SLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>KDKFYIITQLAKGGELFDRILKK---GKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAF</Hsp_hseq>
      <Hsp_midline>+D   +  +   GG+L   +LK        E D + ++ +I  AV+Y+H+  I+HRDLKPEN++   + D     + D G AK L     L     G+L Y+APE+     +    D WS G + +  + G+  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.9442</Hsp_bit-score>
      <Hsp_score>180</Hsp_score>
      <Hsp_evalue>1.56218e-13</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>615</Hsp_query-to>
      <Hsp_hit-from>108</Hsp_hit-from>
      <Hsp_hit-to>261</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEGQKYT-VSVDYWSFGTVVFECITGFRPFLPNMQPVQWHSIVIRKGPHDIVAVEEMNRE</Hsp_qseq>
      <Hsp_hseq>LVLEYAEKGELFNLLVE---RGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYN---IKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISRE</Hsp_hseq>
      <Hsp_midline>L +EY   G+L  +L++      + E + +     I   V Y H   I+HRDLKPEN++L  + +    KI D G A    +G L  +  G+  Y APE+  G  Y   + D WS G ++F  +TG  PF      ++   + ++KG  ++ + +E++RE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.9442</Hsp_bit-score>
      <Hsp_score>180</Hsp_score>
      <Hsp_evalue>1.62067e-13</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>902</Hsp_hit-from>
      <Hsp_hit-to>1024</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>131</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLLKPENC-CGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAK-ELDQGSLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>FAMEFIGGGDL---MWHVQNQRLSVRRAKFYAA--EVLLALKYFHDNGVIYRDLKLENILLTPEGH---IKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPF</Hsp_hseq>
      <Hsp_midline> AME+  GGDL   +   +N    +R     A   ++  A++Y H N +I+RDLK ENI+L  +      KI D G  K E+  G+  ++F GT +++APE+ + Q+YT +VD+W+FG ++++ +    PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>3.23427e-13</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>252</Hsp_hit-from>
      <Hsp_hit-to>415</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>167</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQ----------------QDRV------IYKIIDLGYAKELDQG----------------SLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>LAMEFVPGGDFRTLLI---NTRCLKSGHARFYISEMFCAVNALHDLGYTHRDLKPENFLIDAKGHIKLTDFGLAAGTISNERIESMKIRLEKIKDLEFPAFTEKSIEDRRKMYNQLREKEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPF</Hsp_hseq>
      <Hsp_midline>LAME+  GGD R +L+   N   ++       I ++  AV  LH     HRDLKPEN ++  +                 +R+      + KI DL +    ++                 +   S VG+  Y+A E+ EG+KY  +VDYWS G ++FE + G+ PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>3.29182e-13</Hsp_evalue>
      <Hsp_query-from>160</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>246</Hsp_hit-from>
      <Hsp_hit-to>385</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>140</Hsp_align-len>
      <Hsp_qseq>GGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGS-LCTSFVGTLQYLAPEL-----------------FEGQKYTVSVDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>GGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGISPF</Hsp_hseq>
      <Hsp_midline>GGDL   L K +    M E + + +++ I QA+ YLH   I+HRDLK +NI+L   +      + D G AK+L+       + VGT +Y APE+                  E + Y    D WS G +    +TG  PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>3.61778e-13</Hsp_evalue>
      <Hsp_query-from>136</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>268</Hsp_hit-from>
      <Hsp_hit-to>404</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>141</Hsp_align-len>
      <Hsp_qseq>LLAMEYCSGGDLRKVL----------LKPENCCGMRECDVMAVIYDISQAVQYLHTN-RIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>IILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQ---IKLCDFGVSKKL-INSIADTFVGTSTYMSPERIQGNVYSIKGDVWSLGLMIIELVTGEFPL</Hsp_hseq>
      <Hsp_midline>++ MEY   G L K+L                    E  +  + Y +   + +L+   +IIHRD+KP N+++  +      K+ D G +K+L   S+  +FVGT  Y++PE  +G  Y++  D WS G ++ E +TG  P </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.4034</Hsp_bit-score>
      <Hsp_score>176</Hsp_score>
      <Hsp_evalue>4.35445e-13</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>191</Hsp_hit-from>
      <Hsp_hit-to>315</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>131</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAK-ELDQGSLCTSFVGTLQYLAPELFEGQKYTVS-VDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>LVLEYVDGGELFDYLVSKGK---LPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRI--KIADFGMAALELPNKLLKTS-CGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPF</Hsp_hseq>
      <Hsp_midline>L +EY  GG+L   L+       + E + +     I + V Y H+  I HRDLKPEN++L ++  R+  KI D G A  EL    L TS  G+  Y +PE+  G+ Y     D WS G V+F  +TG  PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>4.90231e-13</Hsp_evalue>
      <Hsp_query-from>232</Hsp_query-from>
      <Hsp_query-to>594</Hsp_query-to>
      <Hsp_hit-from>239</Hsp_hit-from>
      <Hsp_hit-to>377</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>VIYDISQAVQYLHTNRIIHRDLKPENIVLQ-----------QQQDRVIY----------KIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPFLPNMQPVQWHSIVIRKGPHDIVA</Hsp_qseq>
      <Hsp_hseq>VITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLRNNTAKTP-CGTIEYVASEVFTSKRYSMKVDMWSIGCVLFTLLCGYPPFYEKNEKTLLKK--ISRGDYEFLA</Hsp_hseq>
      <Hsp_midline>VI  ++ A++++H   I+HRD+KPEN++ +           Q++D              K++D G AK+L   +  T   GT++Y+A E+F  ++Y++ VD WS G V+F  + G+ PF    +        I +G ++ +A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>1.2803e-12</Hsp_evalue>
      <Hsp_query-from>253</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>457</Hsp_hit-from>
      <Hsp_hit-to>558</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>105</Hsp_align-len>
      <Hsp_qseq>AVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAK-ELDQGSLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPFLPNMQPVQWHSIV</Hsp_qseq>
      <Hsp_hseq>ALDNLHKLDVVYRDLKPENILLDYQGH---IALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKIL</Hsp_hseq>
      <Hsp_midline>A+  LH   +++RDLKPENI+L  Q       + D G  K  +       +F GT +YLAPEL  G  YT +VD+W+ G +++E +TG  P+     P  +  I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YPR111W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:747306:749000:1 gene:YPR111W transcript:YPR111W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF20 description:Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006315]</Hit_def>
  <Hit_accession>YPR111W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>1.69203e-12</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>244</Hsp_hit-from>
      <Hsp_hit-to>407</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>167</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQ----------------QQDRVIYKIIDLGYAKELD----------------------QGSLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>LAMEFVPGGDFRTLLI---NTRILKSGHARFYISEMFCAVNALHELGYTHRDLKPENFLIDATGHIKLTDFGLAAGTVSNERIESMKIRLEEVKNLEFPAFTERSIEDRRKIYHNMRKTEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPF</Hsp_hseq>
      <Hsp_midline>LAME+  GGD R +L+   N   ++       I ++  AV  LH     HRDLKPEN ++                    +R+    I L   K L+                      + +   S VG+  Y+A E+ EG+KY  +VDYWS G ++FE + G+ PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>1.83875e-12</Hsp_evalue>
      <Hsp_query-from>115</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>122</Hsp_hit-from>
      <Hsp_hit-to>264</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>150</Hsp_align-len>
      <Hsp_qseq>LGPRDLPLLAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEGQKYT-VSVDYWSFGTVVFECITGFRPFLPNMQPVQWHSI</Hsp_qseq>
      <Hsp_hseq>IKSKDEIIMVIEYA-GNELFDYIVQRDK---MSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLN---VKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNI</Hsp_hseq>
      <Hsp_midline>+  +D  ++ +EY  G +L   +++ +    M E +       I  AV+Y H ++I+HRDLKPEN++L +  +    KI D G +  +  G+   +  G+  Y APE+  G+ Y    VD WS G +++  +    PF     PV + +I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>2.84643e-12</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>97</Hsp_hit-from>
      <Hsp_hit-to>218</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>129</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>ILLEYCANGSLRRLI--SRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADN---TVKLADFGVSTIVNSSAL--TLAGTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNPPY</Hsp_hseq>
      <Hsp_midline>+ +EYC+ G LR+++    +  G+ E +    +      ++YLH   +IHRD+K  NI+L         K+ D G +  ++  +L  +  GTL ++APE+   +  +   D WS G  V E +T   P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>8.37632e-12</Hsp_evalue>
      <Hsp_query-from>145</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>203</Hsp_hit-from>
      <Hsp_hit-to>337</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>141</Hsp_align-len>
      <Hsp_qseq>MEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKEL--------------DQGSLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>LEYAPHGDFLGLIKK---YGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKN---MKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPF</Hsp_hseq>
      <Hsp_midline>+EY   GD   ++ K      + E         I  AV  LH   IIHRD+KPENI+L +    +  K+ D G AK L              D  +   SFVGT +Y++PEL          D W+FG ++++ + G  PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>9.29191e-12</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>158</Hsp_hit-from>
      <Hsp_hit-to>289</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>138</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEG--------QKYT-VSVDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>IIMEYCSGGDLYEAI--KADAVPKKTKSITHIITQIMDAIEYVHNKGIYHRDIKPENILI-SGIDWTI-KLTDWGLAT-TDKTSMDRN-VGSERYMSPELFDSNLDIKERKEPYDCAKVDLWAMGIVFLNIVFHKNPF</Hsp_hseq>
      <Hsp_midline>+ MEYCSGGDL + +    +    +   +  +I  I  A++Y+H   I HRD+KPENI++    D  I K+ D G A   D+ S+  + VG+ +Y++PELF+         + Y    VD W+ G V    +    PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>9.3171e-12</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>573</Hsp_query-to>
      <Hsp_hit-from>229</Hsp_hit-from>
      <Hsp_hit-to>373</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>156</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCT-----------SFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPFLPNMQPVQWHSIVIRK</Hsp_qseq>
      <Hsp_hseq>LLLQYIPGGELFYHL---KEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLV---LTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSN-----HKVIINK</Hsp_hseq>
      <Hsp_midline>L ++Y  GG+L   L   +    + E  V     +IS A+++LHT  +++RDLKPEN +L Q+   V   + D G +K+    S              S +GT +Y APE+  G+ Y+ + D++S G ++++ + G  P+  +      H ++I K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>1.36013e-11</Hsp_evalue>
      <Hsp_query-from>166</Hsp_query-from>
      <Hsp_query-to>531</Hsp_query-to>
      <Hsp_hit-from>100</Hsp_hit-from>
      <Hsp_hit-to>227</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>132</Hsp_align-len>
      <Hsp_qseq>DLRKVLLKPENCCGMRECD-VMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGS--------LCTSFVGTLQYLAPE-LFEGQKYTVSVDYWSFGTVVFECITGFRPFLP</Hsp_qseq>
      <Hsp_hseq>DLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCD---LKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSG-KPLFP</Hsp_hseq>
      <Hsp_midline>DL+KV+    +       D V    Y I +A++ +H+ ++IHRD+KP N++L    D    K+ D G A+ L   S          T +V T  Y APE +   Q+YT ++D WS G ++ E ++G +P  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>1.39001e-11</Hsp_evalue>
      <Hsp_query-from>124</Hsp_query-from>
      <Hsp_query-to>555</Hsp_query-to>
      <Hsp_hit-from>1105</Hsp_hit-from>
      <Hsp_hit-to>1264</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>168</Hsp_align-len>
      <Hsp_qseq>RDLPLLAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIY--DISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKEL--------------DQGSLCTSF---VGTLQYLAPELFEGQKYTVSV---DYWSFGTVVFECITGFRPF--LPNMQPVQWH</Hsp_qseq>
      <Hsp_hseq>RDKVNIFMEYCEGGSLASLL-----DHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDFNG---IIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPWSNLDNEWAIMYH</Hsp_hseq>
      <Hsp_midline>RD   + MEYC GG L  +L       G  E +++  +Y  ++ + + YLH + ++HRD+KPENI+L       I K +D G A+ +              D G    S    +GT  Y+APE   G      +   D W+ G VV E  TG RP+  L N   + +H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>1.66024e-11</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>90</Hsp_hit-from>
      <Hsp_hit-to>230</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>147</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELD--------------QGSL----CTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>FVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLID---ALEFIHSHGIIHRDLKPENVLLDRD-GRLM--ITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPF</Hsp_hseq>
      <Hsp_midline>  +++  GG+L  +L K      +      A + D   A++++H++ IIHRDLKPEN++L +   R++  I D G A  +D               GS     C SFVGT +Y++PEL    +     D W+ G ++++ + G  PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>2.87264e-11</Hsp_evalue>
      <Hsp_query-from>136</Hsp_query-from>
      <Hsp_query-to>546</Hsp_query-to>
      <Hsp_hit-from>785</Hsp_hit-from>
      <Hsp_hit-to>929</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>153</Hsp_align-len>
      <Hsp_qseq>LLAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAK---------ELDQGSL------CTSFVGTLQYLAPELFEGQ-KYTVSVDYWSFGTVVFECITGFRPFLPNMQPV</Hsp_qseq>
      <Hsp_hseq>FIQMEYCENRTLYD-LIHSENLNQQRD-EYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRN---VKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVLDGTGHYNEKIDMYSLGIIFFEMIY---PFSTGMERV</Hsp_hseq>
      <Hsp_midline> + MEYC    L   L+  EN    R+ +   +   I +A+ Y+H+  IIHRDLKP NI + + ++    KI D G AK         +LD  +L       TS +GT  Y+A E+ +G   Y   +D +S G + FE I    PF   M+ V</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>3.19295e-11</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>531</Hsp_query-to>
      <Hsp_hit-from>433</Hsp_hit-from>
      <Hsp_hit-to>566</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>137</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYL-HTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEG-----QKYTVSVDYWSFGTVVFECITGFRPFLP</Hsp_qseq>
      <Hsp_hseq>MCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSANQGTV--KLCDFGVSGNL-VASLAKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYPP</Hsp_hseq>
      <Hsp_midline>+ MEY  GG L K+  +     G+ E  +  +   +   ++ L   + IIHRD+KP NI+    Q  V  K+ D G +  L   SL  + +G   Y+APE  +        YTV  D WS G  + E   G  P+ P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>3.62016e-11</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>606</Hsp_query-to>
      <Hsp_hit-from>133</Hsp_hit-from>
      <Hsp_hit-to>301</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>177</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLLKPENCCGMREC--------DVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGS----------LCTSFVGTLQYLAPELFEGQK-YTVS--VDYWSFGTVVFECITGFRPFLPNMQPVQWHSIVIRKGPHDIVAVEEM</Hsp_qseq>
      <Hsp_hseq>LVLEYCSRGPVKWC---PENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNG---TVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPFNANSGLELFDSIINK--PLEFPSYEEM</Hsp_hseq>
      <Hsp_midline>L +EYCS G ++     PEN   ++              V+ D+   ++YLH+  I HRD+KP N+++         KI D G A     GS          L +  +GT  + APEL   +K Y+ S  +D WS G  ++  + G  PF  N     + SI+ +  P +  + EEM</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>4.29863e-11</Hsp_evalue>
      <Hsp_query-from>238</Hsp_query-from>
      <Hsp_query-to>585</Hsp_query-to>
      <Hsp_hit-from>146</Hsp_hit-from>
      <Hsp_hit-to>260</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>117</Hsp_align-len>
      <Hsp_qseq>YDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEG-QKYTVSVDYWSFGTVVFECITGFRPFLPNMQPVQWHSIVIRKGPHD</Hsp_qseq>
      <Hsp_hseq>YQIARGMLYLHGLGVCHRDIKPSNVLVDPETG--VLKICDFGSAKKLEHNQPSISYICSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLREIAKLLGPPD</Hsp_hseq>
      <Hsp_midline>Y I++ + YLH   + HRD+KP N+++  +    + KI D G AK+L+      S++ +  Y APEL  G  +YT  +D W  G V+ E + G   F      +Q   I    GP D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>4.42876e-11</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>615</Hsp_query-to>
      <Hsp_hit-from>104</Hsp_hit-from>
      <Hsp_hit-to>257</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEGQKYT-VSVDYWSFGTVVFECITGFRPFLPNMQPVQWHSIVIRKGPHDIVAVEEMNRE</Hsp_qseq>
      <Hsp_hseq>LILEYAEKGELFNLLV---DHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYN---IKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRD</Hsp_hseq>
      <Hsp_midline>L +EY   G+L  +L+   +   + E + +     I   + Y H   I+HRDLKPEN++L    +    KI D G A       L  +  G+  Y APE+  G  Y   + D WS G ++F  +TG  PF      V+   + ++KG  ++    E++R+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>4.75862e-11</Hsp_evalue>
      <Hsp_query-from>124</Hsp_query-from>
      <Hsp_query-to>555</Hsp_query-to>
      <Hsp_hit-from>1337</Hsp_hit-from>
      <Hsp_hit-to>1512</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>184</Hsp_align-len>
      <Hsp_qseq>RDLPLLAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDIS--QAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKEL-DQGSLCTS--------------------------------FVGTLQYLAPELFEGQKYTVSV---DYWSFGTVVFECITGFRPF--LPNMQPVQWH</Hsp_qseq>
      <Hsp_hseq>RDKVNIFMEYCEGGSLAALLEH-----GRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNG---VIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPWANLDNEWAIMYH</Hsp_hseq>
      <Hsp_midline>RD   + MEYC GG L  +L       G  E +++  +Y +   + + YLH + I+HRD+KPENI+L       + K +D G AK++ + G+   S                                 +GT  Y+APE   G      +   D WS G VV E ITG RP+  L N   + +H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>5.80601e-11</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>156</Hsp_hit-from>
      <Hsp_hit-to>281</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>138</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDL------RKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKEL-DQGSLCTSFVGTLQYLAPELFEGQK--YTVSVDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>ILLEICPNGSLMELLKRRKVLTEPE---------VRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYN---LKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPF</Hsp_hseq>
      <Hsp_midline>+ +E C  G L      RKVL +PE         V      I  A++Y+H+ R+IHRDLK  NI      +    KI D G A  L ++     +  GT  Y+APE+  G+   ++  VD WS G +++  + G  PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>7.34267e-11</Hsp_evalue>
      <Hsp_query-from>238</Hsp_query-from>
      <Hsp_query-to>531</Hsp_query-to>
      <Hsp_hit-from>115</Hsp_hit-from>
      <Hsp_hit-to>210</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>100</Hsp_align-len>
      <Hsp_qseq>YDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELD-QGSLCTSFVGTLQYLAPELFEGQK-YTVSVDYWSFGTVVFECITGFRPFLP</Hsp_qseq>
      <Hsp_hseq>WQLLQGLAFCHENKILHRDLKPQNLLINK---RGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITG-KPLFP</Hsp_hseq>
      <Hsp_midline>+ + Q + + H N+I+HRDLKP+N+++ +   R   K+ D G A+      +  +S V TL Y AP++  G + Y+ S+D WS G ++ E ITG +P  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>7.72117e-11</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>127</Hsp_hit-from>
      <Hsp_hit-to>252</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKEL-DQGSLCTSFVGTLQYLAPEL------FEGQKYTVSVDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>IVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLI---SGVHYIHSKGLVHRDLKLENLLLDKNENLV---ITDFGFVNEFCSRNELMKTSCGSPCYAAPELVISAEPYEARK----ADIWSCGVILYAILAGYLPW</Hsp_hseq>
      <Hsp_midline>+ +EY  GG+  K + K      M  C + + +      V Y+H+  ++HRDLK EN++L + ++ V   I D G+  E   +  L  +  G+  Y APEL      +E +K     D WS G +++  + G+ P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>8.54635e-11</Hsp_evalue>
      <Hsp_query-from>19</Hsp_query-from>
      <Hsp_query-to>531</Hsp_query-to>
      <Hsp_hit-from>10</Hsp_hit-from>
      <Hsp_hit-to>224</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>52</Hsp_gaps>
      <Hsp_align-len>219</Hsp_align-len>
      <Hsp_qseq>SGPWERKERLGAGGFGHVCMWQNKVPEEME--KALGPRDLPLLAMEYCSGGDLRK-----------VLLKPENCCGMRECDVMA-----------------------VIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELD-----------QGSLCTSFVGTLQYLAPE-LFEGQKYTVSVDYWSFGTVVFECITGFRPFLP</Hsp_qseq>
      <Hsp_hseq>SSDFQLKSLLGEGAYGVVCSATHKPTGEIVAIKKIEPFDKPLFALRTLREIKILKHFKHENIITIFNIQRPDSFENFNEVYIIQELMQTDLHRVISTQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCD---LKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLR-RPIFP</Hsp_hseq>
      <Hsp_midline>S  ++ K  LG G +G VC   +K   E+   K + P D PL A+       + K            + +P++     E  ++                         IY   +AV+ LH + +IHRDLKP N+++    D    K+ D G A+ +D           Q S  T +V T  Y APE +    KY+ ++D WS G ++ E     RP  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>1.27379e-10</Hsp_evalue>
      <Hsp_query-from>145</Hsp_query-from>
      <Hsp_query-to>549</Hsp_query-to>
      <Hsp_hit-from>533</Hsp_hit-from>
      <Hsp_hit-to>664</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>139</Hsp_align-len>
      <Hsp_qseq>MEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELD----QGSLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPFLPNMQPVQ</Hsp_qseq>
      <Hsp_hseq>LEYVPGGSVSSML---NNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDI---KGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPF-PDFSQMQ</Hsp_hseq>
      <Hsp_midline>+EY  GG +  +L    N     E  +      I   V YLH   IIHRD+K  NI++     +   KI D G +K+L     + +   S  G++ +++PE+ +    T   D WS G VV E  TG  PF P+   +Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>4.59802e-10</Hsp_evalue>
      <Hsp_query-from>229</Hsp_query-from>
      <Hsp_query-to>531</Hsp_query-to>
      <Hsp_hit-from>172</Hsp_hit-from>
      <Hsp_hit-to>286</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>116</Hsp_align-len>
      <Hsp_qseq>AVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQ--------------QDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPE-LFEGQKYTVSVDYWSFGTVVFECITGFRPFLP</Hsp_qseq>
      <Hsp_hseq>SILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVENKNPYTAYVSTRWYRSPEILLRSGYYSKPLDIWAFGCVAVE-VTVFRALFP</Hsp_hseq>
      <Hsp_midline>+++  I   ++++H +   HRDLKPENI++                 QD  + K+ D G A+ ++  +  T++V T  Y +PE L     Y+  +D W+FG V  E +T FR   P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YIL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:287790:288908:-1 gene:YIL035C transcript:YIL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA1 description:Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000001297]</Hit_def>
  <Hit_accession>YIL035C</Hit_accession>
  <Hit_len>372</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>7.10264e-10</Hsp_evalue>
      <Hsp_query-from>133</Hsp_query-from>
      <Hsp_query-to>528</Hsp_query-to>
      <Hsp_hit-from>148</Hsp_hit-from>
      <Hsp_hit-to>272</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>133</Hsp_align-len>
      <Hsp_qseq>PLLAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELF-EGQKYTVSVDYWSFGTVVFECITGFRPFL</Hsp_qseq>
      <Hsp_hseq>PALVFEYVDNVDFR--ILYPK----LTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKL--RLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFF</Hsp_hseq>
      <Hsp_midline>P L  EY    D R  +L P+    + + ++   ++++ +A+ Y H+  I+HRD+KP N+++  +  ++  ++ID G A+           V +  +  PEL  + + Y  S+D WSFGT++   I    PF </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>7.85466e-10</Hsp_evalue>
      <Hsp_query-from>202</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>1200</Hsp_hit-from>
      <Hsp_hit-to>1304</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>53</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>109</Hsp_align-len>
      <Hsp_qseq>CGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEGQKYTVS-VDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>TNMTEFEAKLIFKQVVAGIKHLHDQGIVHRDIKDENVIVDS---KGFVKIIDFGSAAYVKSGPFDV-FVGTIDYAAPEVLGGNPYEGQPQDIWAIGILLYTVVFKENPF</Hsp_hseq>
      <Hsp_midline>  M E +   +   +   +++LH   I+HRD+K EN+++     +   KIID G A  +  G     FVGT+ Y APE+  G  Y     D W+ G +++  +    PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>8.18258e-10</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>127</Hsp_hit-from>
      <Hsp_hit-to>252</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>132</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKE-LDQGSLCTSFVGTLQYLAPELFEGQKY--TVSVDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>IVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLI---SGVNYMHYKGLVHRDLKLENLLLDKHENLV---ITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLPW</Hsp_hseq>
      <Hsp_midline>+ +E+ SGG+  K + +         C + A +      V Y+H   ++HRDLK EN++L + ++ V   I D G+  E  +   L  +  G+  Y APEL    K       D WS G +++  + G+ P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>9.30891e-10</Hsp_evalue>
      <Hsp_query-from>223</Hsp_query-from>
      <Hsp_query-to>528</Hsp_query-to>
      <Hsp_hit-from>263</Hsp_hit-from>
      <Hsp_hit-to>365</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>108</Hsp_align-len>
      <Hsp_qseq>VMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVG-----TLQYLAPELFEGQK-YTVSVDYWSFGTVVFECITGFRPFL</Hsp_qseq>
      <Hsp_hseq>VRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDG---CVKIGDLGLARKF-HNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELI-GLQPIF</Hsp_hseq>
      <Hsp_midline>V ++++ +   V YLH N ++HRDLKP NI++         KI DLG A++     L T + G     T+ Y APEL  G + YT +VD WS G +  E I G +P  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>1.32345e-09</Hsp_evalue>
      <Hsp_query-from>217</Hsp_query-from>
      <Hsp_query-to>570</Hsp_query-to>
      <Hsp_hit-from>104</Hsp_hit-from>
      <Hsp_hit-to>219</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>120</Hsp_align-len>
      <Hsp_qseq>CDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQ-GSLCTSFVGTLQYLAPELFEGQK-YTVSVDYWSFGTVVFECITGFRPFLPNMQPVQWHSIVIR</Hsp_qseq>
      <Hsp_hseq>ADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQ---IKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRI-PYLPGQNDVDQMEVTFR</Hsp_hseq>
      <Hsp_midline> D+ A +    + V + H N I+HRDLKP N++          K+ D G A+ +     + TS V T  Y APEL  G K YT ++D WS G +  E +    P+LP    V    +  R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>1.3968e-09</Hsp_evalue>
      <Hsp_query-from>244</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>1287</Hsp_hit-from>
      <Hsp_hit-to>1380</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>98</Hsp_align-len>
      <Hsp_qseq>ISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGY---AKELDQGSLCTSFVGTLQYLAPELFE-GQKYTVSVDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>VLKGLAYLHSKGILHRDMKADNLLLDQDG---ICKISDFGISRKSKDIYSNSDMT-MRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPW</Hsp_hseq>
      <Hsp_midline>+ + + YLH+  I+HRD+K +N++L Q     I KI D G    +K++   S  T   GT+ ++APE+ +  Q Y+  VD WS G +V E   G RP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>1.53697e-09</Hsp_evalue>
      <Hsp_query-from>193</Hsp_query-from>
      <Hsp_query-to>513</Hsp_query-to>
      <Hsp_hit-from>140</Hsp_hit-from>
      <Hsp_hit-to>245</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>53</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>108</Hsp_align-len>
      <Hsp_qseq>ENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEGQK-YTVSVDYWSFGTVVFECITG</Hsp_qseq>
      <Hsp_hseq>DNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSG--IAKVCDFGSAQRLDDNTELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKG</Hsp_hseq>
      <Hsp_midline>+N   M    +    + I +A+  LH+  I H DLKP NI++       I K+ D G A+ LD  +   ++  +  Y APEL    K YT  +D WS G ++ E I G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>1.72551e-09</Hsp_evalue>
      <Hsp_query-from>232</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>293</Hsp_hit-from>
      <Hsp_hit-to>420</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>129</Hsp_align-len>
      <Hsp_qseq>VIYDISQAVQYLHTNRIIHRDLKPENIVL-------------------QQQQDRVIY------------KIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>VIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKNTKTP-CGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTMLCGFPPF</Hsp_hseq>
      <Hsp_midline>VI  ++ AV+++H+  ++HRD+KPEN++                    Q + D  I+            K+ D G +K++   +  T   GT+ Y APE+ + + Y++ VD W  G V++  + GF PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>2.22307e-09</Hsp_evalue>
      <Hsp_query-from>136</Hsp_query-from>
      <Hsp_query-to>513</Hsp_query-to>
      <Hsp_hit-from>76</Hsp_hit-from>
      <Hsp_hit-to>218</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>149</Hsp_align-len>
      <Hsp_qseq>LLAMEYCSGGDLRKVLLKPEN-----CCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSF-VGTLQYLAPELFEGQ-----------------KYTVSVDYWSFGTVVFECITG</Hsp_qseq>
      <Hsp_hseq>IMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQIDMQKIIKQLCSAISFAHSLGIAHRDIKPENILLTINGD---IKLADWGHAI---QSPKSNDFQIGTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFG</Hsp_hseq>
      <Hsp_midline>++ +EYC  GDL   L   ++        + + D+  +I  +  A+ + H+  I HRD+KPENI+L    D    K+ D G+A    Q      F +GT  Y APE F G+                   T   DYWS G  +F  + G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>2.94919e-09</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>258</Hsp_hit-from>
      <Hsp_hit-to>393</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEG-QKYTVSVDYWSFGTVVFECITGFRPFLPNMQPVQWHSI</Hsp_qseq>
      <Hsp_hseq>MIFEYADN-DLSGLLLNKEVQISHSQCK--HLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGN---LKITDFGLARKMNSRADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESI</Hsp_hseq>
      <Hsp_midline>+  EY    DL  +LL  E      +C    +   +   ++YLH N+I+HRD+K  NI++  Q +    KI D G A++++  +  T+ V TL Y  PEL  G   Y   VD W  G ++ E       F  + +  Q  SI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>3.32754e-09</Hsp_evalue>
      <Hsp_query-from>208</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>947</Hsp_hit-from>
      <Hsp_hit-to>1049</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>53</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>107</Hsp_align-len>
      <Hsp_qseq>MRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEGQKYTVS-VDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>MVEHEAKLVFKQVVASIKHLHDQGIVHRDIKDENVIVDSHG---FVKLIDFGSAAYIKSGPFDV-FVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLYTIIYKENPY</Hsp_hseq>
      <Hsp_midline>M E +   V   +  ++++LH   I+HRD+K EN+++         K+ID G A  +  G     FVGT+ Y APE+  G  Y     D W+ G +++  I    P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>4.61149e-09</Hsp_evalue>
      <Hsp_query-from>166</Hsp_query-from>
      <Hsp_query-to>501</Hsp_query-to>
      <Hsp_hit-from>127</Hsp_hit-from>
      <Hsp_hit-to>242</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>122</Hsp_align-len>
      <Hsp_qseq>DLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSL---------CTSFVGTLQYLAPE-LFEGQKYTVSVDYWSFGTVVFE</Hsp_qseq>
      <Hsp_hseq>DLAKVI---HSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNG---CLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAE</Hsp_hseq>
      <Hsp_midline>DL KV+    +   + E  +   +Y I   ++Y+H+  +IHRDLKP NI+          KI D G A+ +  G            T++V T  Y APE L   Q Y+ SVD W+ G ++ E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.5362</Hsp_bit-score>
      <Hsp_score>140</Hsp_score>
      <Hsp_evalue>6.84057e-09</Hsp_evalue>
      <Hsp_query-from>163</Hsp_query-from>
      <Hsp_query-to>501</Hsp_query-to>
      <Hsp_hit-from>154</Hsp_hit-from>
      <Hsp_hit-to>275</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>127</Hsp_align-len>
      <Hsp_qseq>GDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAK-------------ELDQGSLCTSFVGTLQYLAPELFEGQK-YTVSVDYWSFGTVVFE</Hsp_qseq>
      <Hsp_hseq>ADLSGVLHNPR--INLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNG---VLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAE</Hsp_hseq>
      <Hsp_midline> DL  VL  P     +  CD+  ++  I + + Y+H  + +HRD+K  NI++       + K+ D G A+                 G+  TS V T  Y APEL  G K YT +VD W  G V  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YMR291W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:852630:854390:1 gene:YMR291W transcript:YMR291W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TDA1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000004905]</Hit_def>
  <Hit_accession>YMR291W</Hit_accession>
  <Hit_len>586</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>7.38098e-09</Hsp_evalue>
      <Hsp_query-from>127</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>127</Hsp_hit-from>
      <Hsp_hit-to>292</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>168</Hsp_align-len>
      <Hsp_qseq>DLPLLAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQ-----------------QQDRVIYKII--DLGYAKELDQGSLCT--SFVGTLQYLAPELFEGQ--------------KYTVSVDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>DNIVLITQLCQKGDLYEKIV--ENQCLDLETQVTSYCACLVSVLEFLHSQGIVHRDLKAENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLVLADFGLAAEYNTSKVNSLKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGCPVDIWALGVLTYFMAFGYTPF</Hsp_hseq>
      <Hsp_midline>D  +L  + C  GDL + ++  EN C   E  V +    +   +++LH+  I+HRDLK EN++ +                  + D + + ++  D G A E +   + +   FVGT+ Y+APE+ + +              KY   VD W+ G + +    G+ PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YAR018C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:170396:171703:-1 gene:YAR018C transcript:YAR018C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN3 description:Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol [Source:SGD;Acc:S000000071]</Hit_def>
  <Hit_accession>YAR018C</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>1.27486e-08</Hsp_evalue>
      <Hsp_query-from>124</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>96</Hsp_hit-from>
      <Hsp_hit-to>288</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>63</Hsp_gaps>
      <Hsp_align-len>195</Hsp_align-len>
      <Hsp_qseq>RDLPLLAMEYCSGGDLRKVLLK--------PEN---------------CCGMRECDVMAVIYD-ISQAVQYLHTNRIIHRDLKPENIVL---------QQQQD---------------------------RVIYKIIDLGYAKELDQG-SLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>KEVLYLYMEYCSRGDLSQMIKHYKQEHKYIPEKIVWGILAQLLTALYKCHYGVELPTLTTIYDRMKPPVK--GKNIVIHRDLKPGNIFLSYDDSDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLAKSLETSIQFATTYVGTPYYMSPEVLMDQPYSPLSDIWSLGCVIFEMCSLHPPF</Hsp_hseq>
      <Hsp_midline>+++  L MEYCS GDL +++          PE                C    E   +  IYD +   V+    N +IHRDLKP NI L          +Q D                           +V+ K+ D G AK L+      T++VGT  Y++PE+   Q Y+   D WS G V+FE  +   PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>71</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>1.44161e-08</Hsp_evalue>
      <Hsp_query-from>208</Hsp_query-from>
      <Hsp_query-to>531</Hsp_query-to>
      <Hsp_hit-from>135</Hsp_hit-from>
      <Hsp_hit-to>241</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>110</Hsp_align-len>
      <Hsp_qseq>MRECDVMAVIYDISQAVQYLHT-NRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPEL-FEGQKYTVSVDYWSFGTVVFECITGFRPFLP</Hsp_qseq>
      <Hsp_hseq>MSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSL--KLCDFGSAKQLKPTEPNVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLG-QPMFP</Hsp_hseq>
      <Hsp_midline>M   ++   ++ + +++ YLH    + HRD+KP+N+++  +   +  K+ D G AK+L       S++ +  Y APEL F    YT  +D WS G V+ E + G +P  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>72</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>1.51975e-08</Hsp_evalue>
      <Hsp_query-from>223</Hsp_query-from>
      <Hsp_query-to>501</Hsp_query-to>
      <Hsp_hit-from>113</Hsp_hit-from>
      <Hsp_hit-to>204</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>95</Hsp_align-len>
      <Hsp_qseq>VMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQG-SLCTSFVGTLQYLAPE-LFEGQKYTVSVDYWSFGTVVFE</Hsp_qseq>
      <Hsp_hseq>VKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGN---LKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAE</Hsp_hseq>
      <Hsp_midline>V   +  + + + Y H++RI+HRDLKP+N+++ +  +    K+ D G A+         T  + TL Y APE L  G++Y+  VD WS G +  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>73</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>1.7641e-08</Hsp_evalue>
      <Hsp_query-from>181</Hsp_query-from>
      <Hsp_query-to>531</Hsp_query-to>
      <Hsp_hit-from>459</Hsp_hit-from>
      <Hsp_hit-to>571</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>117</Hsp_align-len>
      <Hsp_qseq>LLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPFLP</Hsp_qseq>
      <Hsp_hseq>LLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAP-DKPELKIIDFGSSCE--EARTVYTYIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAELFLGI-PIFP</Hsp_hseq>
      <Hsp_midline>LLK     G+    +      I  ++  L  +++IH DLKPENI+L    D+   KIID G + E  +     +++ +  Y APE+  G  Y+ S+D WS G +V E   G  P  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>74</Hit_num>
  <Hit_id>YDL079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:312951:314748:-1 gene:YDL079C transcript:YDL079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRK1 description:Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication [Source:SGD;Acc:S000002237]</Hit_def>
  <Hit_accession>YDL079C</Hit_accession>
  <Hit_len>501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>1.87283e-08</Hsp_evalue>
      <Hsp_query-from>208</Hsp_query-from>
      <Hsp_query-to>513</Hsp_query-to>
      <Hsp_hit-from>260</Hsp_hit-from>
      <Hsp_hit-to>361</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>53</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>104</Hsp_align-len>
      <Hsp_qseq>MRECDVMAVIYDISQAVQYLHT-NRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCTSFVGTLQYLAPEL-FEGQKYTVSVDYWSFGTVVFECITG</Hsp_qseq>
      <Hsp_hseq>MPRVEIKFYAYQLFKALNYLHNVPRICHRDIKPQNLLVDPTT--FSFKICDFGSAKCLKPDQPNVSYICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLG</Hsp_hseq>
      <Hsp_midline>M   ++    Y + +A+ YLH   RI HRD+KP+N+++        +KI D G AK L       S++ +  Y APEL F    Y+  VD WS   V+ E + G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>75</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>2.25504e-08</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>540</Hsp_query-to>
      <Hsp_hit-from>93</Hsp_hit-from>
      <Hsp_hit-to>228</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>143</Hsp_align-len>
      <Hsp_qseq>LAMEYCSGGDLRKVLLKPENCCGMRECDVMAVIYD-ISQAVQYLHTN-RIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKEL--DQGSLCTSF--VGTLQYLAPELFEGQK--YTVSVDYWSFGTVVFECITGFRPF-LPNMQ</Hsp_qseq>
      <Hsp_hseq>IILEMADGGDLFD---KIEPDVGV-DSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENILLDKNGN---LKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQTPWELPSLE</Hsp_hseq>
      <Hsp_midline>+ +E   GGDL     K E   G+ + DV    +  +  A+ YLH    + HRD+KPENI+L +  +    K+ D G A +     G+L  S    G+  Y+APE+   ++  Y    D WS G ++F  +TG  P+ LP+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>76</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>4.01794e-08</Hsp_evalue>
      <Hsp_query-from>229</Hsp_query-from>
      <Hsp_query-to>513</Hsp_query-to>
      <Hsp_hit-from>132</Hsp_hit-from>
      <Hsp_hit-to>229</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>101</Hsp_align-len>
      <Hsp_qseq>AVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAK-----ELDQGSLCTSFVGTLQYLAPE-LFEGQKYTVSVDYWSFGTVVFECITG</Hsp_qseq>
      <Hsp_hseq>SFTYQILCGLKYIHSADVLHRDLKPGNLLVNAD---CQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGG</Hsp_hseq>
      <Hsp_midline>+  Y I   ++Y+H+  ++HRDLKP N+++         KI D G A+      ++     T +V T  Y APE +   Q YT ++D WS G ++ E + G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>77</Hit_num>
  <Hit_id>YJL057C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:328118:330121:-1 gene:YJL057C transcript:YJL057C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IKS1 description:Protein kinase of unknown cellular role; putative serine/threonine kinase; expression is induced during mild heat stress; deletion mutants are hypersensitive to copper sulphate and resistant to sorbate; interacts with an N-terminal fragment of Sst2p [Source:SGD;Acc:S000003593]</Hit_def>
  <Hit_accession>YJL057C</Hit_accession>
  <Hit_len>667</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>4.31224e-08</Hsp_evalue>
      <Hsp_query-from>136</Hsp_query-from>
      <Hsp_query-to>546</Hsp_query-to>
      <Hsp_hit-from>271</Hsp_hit-from>
      <Hsp_hit-to>469</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>62</Hsp_gaps>
      <Hsp_align-len>199</Hsp_align-len>
      <Hsp_qseq>LLAMEYCSGGDLRKVLLK-----------PENC----------------CGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVL----------------QQQQDRVIYKII--DLGYAKELDQGSLCTSFVGTLQYLAPEL-FEGQ----------------KYTVSVDYWSFGTVVFECITGFRPFLPNMQPV</Hsp_qseq>
      <Hsp_hseq>FILQQYCSGGNLEDCILRKVFNRFSDTESPEERKKKFRTRKKNHGKSGEVGLSTEQLVSIIRDIARGLHELHSIGLIHRDLKPSNCLLLTPFKSDNENDNVYDREHNSDEFFPSIVIGDLGESQLEGESRLGTGCTGTLEFTAPDLIIQGRPVSSSTLPSRSSHTYNEYTFASDMYSLGMICYFIVFGELPFEPQLDIV</Hsp_hseq>
      <Hsp_midline> +  +YCSGG+L   +L+           PE                   G+    ++++I DI++ +  LH+  +IHRDLKP N +L                +   D     I+  DLG ++   +  L T   GTL++ AP+L  +G+                +YT + D +S G + +  + G  PF P +  V</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>78</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>2.58499e-07</Hsp_evalue>
      <Hsp_query-from>145</Hsp_query-from>
      <Hsp_query-to>513</Hsp_query-to>
      <Hsp_hit-from>403</Hsp_hit-from>
      <Hsp_hit-to>525</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>129</Hsp_align-len>
      <Hsp_qseq>MEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQG-----SLCTSFVGTLQYLAPELFEGQKYTVS-VDYWSFGTVVFECITG</Hsp_qseq>
      <Hsp_hseq>MEYCAGGDLFTLVVAAGKLEYM-EADCF--FKQLIRGVVYMHEMGVCHRDLKPENLLLTHDG---VLKITDFGNSECFKMAWEKNIHLSGGVCGSSPYIAPEEYIKEEFDPRPVDIWACGVIYMAMRTG</Hsp_hseq>
      <Hsp_midline>MEYC+GGDL  +++       M E D       + + V Y+H   + HRDLKPEN++L       + KI D G ++           L     G+  Y+APE +  +++    VD W+ G +     TG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>79</Hit_num>
  <Hit_id>YNL183C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:293137:295509:-1 gene:YNL183C transcript:YNL183C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NPR1 description:Protein kinase; stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p; negatively regulates Ldb19p-mediated endocytosis through phosphorylation of Ldb19p, which prevents its association with the plasma membrane; Npr1p activity is negatively regulated via phosphorylation by the TOR complex; NPR1 has a paralog, PRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005127]</Hit_def>
  <Hit_accession>YNL183C</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>3.0361e-07</Hsp_evalue>
      <Hsp_query-from>124</Hsp_query-from>
      <Hsp_query-to>507</Hsp_query-to>
      <Hsp_hit-from>510</Hsp_hit-from>
      <Hsp_hit-to>634</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>RDLPLLAMEYCSGGDLRKVLLK-----PENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLG--------YAKELDQGSLCTSFVGTLQYLAPELFEGQKYTVS-VDYWSFGTVVFECI</Hsp_qseq>
      <Hsp_hseq>NDRILQVMEYCEY-DLFAIVMSNKMSYEEICCCFKQ---------ILTGVQYLHSIGLAHRDLKLDNCVINEKG---IVKLIDFGAAVVFSYPFSKNLVEAS---GIVGSDPYLAPEVCIFAKYDPRPVDIWS-SAIIFACM</Hsp_hseq>
      <Hsp_midline> D  L  MEYC   DL  +++       E CC  ++         I   VQYLH+  + HRDLK +N V+ ++    I K+ID G        ++K L + S     VG+  YLAPE+    KY    VD WS   ++F C+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>80</Hit_num>
  <Hit_id>YFL029C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:78055:79161:-1 gene:YFL029C transcript:YFL029C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CAK1 description:Cyclin-dependent kinase-activating kinase; required for passage through the cell cycle; phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases [Source:SGD;Acc:S000001865]</Hit_def>
  <Hit_accession>YFL029C</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>3.92677e-07</Hsp_evalue>
      <Hsp_query-from>250</Hsp_query-from>
      <Hsp_query-to>495</Hsp_query-to>
      <Hsp_hit-from>142</Hsp_hit-from>
      <Hsp_hit-to>234</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>93</Hsp_align-len>
      <Hsp_qseq>QAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYK--IIDLGYAKELDQGSLCT--------SFVGTLQYLAPELFEGQK-YTVSVDYWSFGTVV</Hsp_qseq>
      <Hsp_hseq>EGIAFLHENKIIHRDIKPQNIMLTNNTSTVSPKLYIIDFGISYDMANNSQTSAEPMDSKVTDISTGIYKAPEVLFGVKCYDGGVDVWSLLIII</Hsp_hseq>
      <Hsp_midline>+ + +LH N+IIHRD+KP+NI+L      V  K  IID G + ++   S  +        + + T  Y APE+  G K Y   VD WS   ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>81</Hit_num>
  <Hit_id>YOR267C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:822588:824867:-1 gene:YOR267C transcript:YOR267C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRK1 description:Protein kinase; implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005793]</Hit_def>
  <Hit_accession>YOR267C</Hit_accession>
  <Hit_len>759</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>6.59308e-07</Hsp_evalue>
      <Hsp_query-from>145</Hsp_query-from>
      <Hsp_query-to>507</Hsp_query-to>
      <Hsp_hit-from>296</Hsp_hit-from>
      <Hsp_hit-to>414</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>128</Hsp_align-len>
      <Hsp_qseq>MEYCSGGDLRKVLLKPENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKEL-----DQGSLCTSFVGTLQYLAPELFEGQKY--TVSVDYWSFGTVVFECI</Hsp_qseq>
      <Hsp_hseq>MEYCPI-DFFAVVMTGK----MSRGEINCCLKQLTEGVKYLHSMGLAHRDLKLDNCVMTSQG---ILKLIDFGSAVVFRYPFEDGVTMAHGIVGSDPYLAPEVITSTKSYDPQCVDIWSIG-IIYCCM</Hsp_hseq>
      <Hsp_midline>MEYC   D   V++  +    M   ++   +  +++ V+YLH+  + HRDLK +N V+  Q    I K+ID G A        D  ++    VG+  YLAPE+    K      VD WS G +++ C+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>82</Hit_num>
  <Hit_id>YDL214C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:74446:76545:-1 gene:YDL214C transcript:YDL214C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR2 description:Serine/threonine protein kinase; inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance; PRR2 has a paralog, NPR1, that arose from the whole genome duplication [Source:SGD;Acc:S000002373]</Hit_def>
  <Hit_accession>YDL214C</Hit_accession>
  <Hit_len>699</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>7.01242e-07</Hsp_evalue>
      <Hsp_query-from>250</Hsp_query-from>
      <Hsp_query-to>576</Hsp_query-to>
      <Hsp_hit-from>470</Hsp_hit-from>
      <Hsp_hit-to>582</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>116</Hsp_align-len>
      <Hsp_qseq>QAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKEL-----DQGSLCTSFVGTLQYLAPELFEGQKYT-VSVDYWSFGTVVFECITGFRPF-LPNMQPVQWHSIVIRKG</Hsp_qseq>
      <Hsp_hseq>NGVKYLHDIGLSHRDLKLDNCVVTR---RGILKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFYFNEYDPRALDVWSVGIIFFCMITRRFPWKYPKVKDVQFKAFCSGRG</Hsp_hseq>
      <Hsp_midline>  V+YLH   + HRDLK +N V+ +   R I K+ID G +         Q       VG+  YL+PE+F   +Y   ++D WS G + F  IT   P+  P ++ VQ+ +    +G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>83</Hit_num>
  <Hit_id>YKL168C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:131288:133462:-1 gene:YKL168C transcript:YKL168C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KKQ8 description:Putative serine/threonine protein kinase with unknown cellular role; KKQ8 has a paralog, HAL5, that arose from the whole genome duplication [Source:SGD;Acc:S000001651]</Hit_def>
  <Hit_accession>YKL168C</Hit_accession>
  <Hit_len>724</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>1.97272e-06</Hsp_evalue>
      <Hsp_query-from>145</Hsp_query-from>
      <Hsp_query-to>513</Hsp_query-to>
      <Hsp_hit-from>513</Hsp_hit-from>
      <Hsp_hit-to>640</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>131</Hsp_align-len>
      <Hsp_qseq>MEYCSGGDLRKVLLKPENCCG-MRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQG-----SLCTSFVGTLQYLAPELF-EGQKYTVS-VDYWSFGTVVFECITG</Hsp_qseq>
      <Hsp_hseq>MEFCPAGDLYGMLVGKSKLKGRLHPLEADCFMKQLLHGVKFMHDHGIAHCDLKPENILFYPHG---LLKICDFGTSSVFQTAWERRVHAQKGIIGSEPYVAPEEFVDGEYYDPRLIDCWSCGVVYITMILG</Hsp_hseq>
      <Hsp_midline>ME+C  GDL  +L+      G +   +    +  +   V+++H + I H DLKPENI+        + KI D G +                 +G+  Y+APE F +G+ Y    +D WS G V    I G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>84</Hit_num>
  <Hit_id>YKL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:347214:349136:-1 gene:YKL048C transcript:YKL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ELM1 description:Serine/threonine protein kinase; regulates the orientation checkpoint, the morphogenesis checkpoint and the metabolic switch from fermentative to oxidative metabolism by phosphorylating the activation loop of Kin4p, Hsl1p and Snf4p respectively; cooperates with Hsl7p in recruiting Hsl1p to the septin ring, a prerequisite for subsequent recruitment, phosphorylation, and degradation of Swe1p; forms part of the bud neck ring; regulates cytokinesis [Source:SGD;Acc:S000001531]</Hit_def>
  <Hit_accession>YKL048C</Hit_accession>
  <Hit_len>640</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>3.23791e-06</Hsp_evalue>
      <Hsp_query-from>232</Hsp_query-from>
      <Hsp_query-to>564</Hsp_query-to>
      <Hsp_hit-from>239</Hsp_hit-from>
      <Hsp_hit-to>367</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>137</Hsp_align-len>
      <Hsp_qseq>VIYDISQAVQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLG-------------------YAKELDQGSLCTSFVGTLQYLAPELF---EGQKYTVS----VDYWSFGTVVFECITGFRPFLPNMQPVQWHSIV</Hsp_qseq>
      <Hsp_hseq>ILEDMTKGLEYLHSQGCIHRDIKPSNILLDEEEK--VAKLSDFGSCIFTPQSLPFSDANFEDCFQRELNK------IVGTPAFIAPELCHLGNSKRDFVTDGFKLDIWSLGVTLYCLLYNELPFFGENEFETYHKII</Hsp_hseq>
      <Hsp_midline>++ D+++ ++YLH+   IHRD+KP NI+L +++   + K+ D G                   + +EL++       VGT  ++APEL      ++  V+    +D WS G  ++  +    PF    +   +H I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>85</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>4.49062e-06</Hsp_evalue>
      <Hsp_query-from>391</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>567</Hsp_hit-from>
      <Hsp_hit-to>611</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>20</Hsp_identity>
      <Hsp_positive>29</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>45</Hsp_align-len>
      <Hsp_qseq>LCTSFVGTLQYLAPELFEGQKYTVSVDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>MAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPF</Hsp_hseq>
      <Hsp_midline>+  S VGT  Y+APE+F  Q Y    D+WS G +++EC+ G+ PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>86</Hit_num>
  <Hit_id>YDL028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:400997:403291:-1 gene:YDL028C transcript:YDL028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MPS1 description:Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]</Hit_def>
  <Hit_accession>YDL028C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>5.16233e-06</Hsp_evalue>
      <Hsp_query-from>256</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>551</Hsp_hit-from>
      <Hsp_hit-to>654</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>108</Hsp_align-len>
      <Hsp_qseq>VQYLHTNRIIHRDLKPENIVLQQQQDRVIYKIIDLGYAKELDQGSLCT---SFVGTLQYLAPELF-------------EGQKYTVS--VDYWSFGTVVFECITGFRPF</Hsp_qseq>
      <Hsp_hseq>IKVVHDAGIVHSDLKPANFVLVKG----ILKIIDFGIANAVPEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYGKPPY</Hsp_hseq>
      <Hsp_midline>++ +H   I+H DLKP N VL +     I KIID G A  + + ++     + +GT  Y+APE               EG K+ V    D WS G ++++ I G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>87</Hit_num>
  <Hit_id>YHR079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:258244:261591:-1 gene:YHR079C transcript:YHR079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IRE1 description:Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; role in homeostatic adaptation to ER stress; Kar2p binds inactive Ire1p and releases from it upon ER stress [Source:SGD;Acc:S000001121]</Hit_def>
  <Hit_accession>YHR079C</Hit_accession>
  <Hit_len>1115</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>7.28099e-06</Hsp_evalue>
      <Hsp_query-from>193</Hsp_query-from>
      <Hsp_query-to>444</Hsp_query-to>
      <Hsp_hit-from>764</Hsp_hit-from>
      <Hsp_hit-to>862</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>99</Hsp_align-len>
      <Hsp_qseq>ENCCGMRECDVMAVIYDISQAVQYLHTNRIIHRDLKPENIVL----------QQQQDRVIYKIIDLGYAKELDQG--SLCTSF---VGTLQYLAPELFE</Hsp_qseq>
      <Hsp_hseq>ENLKLQKEYNPISLLRQIASGVAHLHSLKIIHRDLKPQNILVSTSSRFTADQQTGAENLRILISDFGLCKKLDSGQSSFRTNLNNPSGTSGWRAPELLE</Hsp_hseq>
      <Hsp_midline>EN    +E + ++++  I+  V +LH+ +IIHRDLKP+NI++          Q   + +   I D G  K+LD G  S  T+     GT  + APEL E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>102</Statistics_hsp-len>
      <Statistics_eff-space>2996039179</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054693-RA transcript Note:&quot;Similar to Trmt1l TRMT1-like protein (Rattus norvegicus)&quot; offset:0 AED:0.24 eAED:0.24 QI:0|0.75|0.6|1|0.75|0.6|5|2224|171</Iteration_query-def>
  <Iteration_query-len>2740</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>1840182938</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054694-RA transcript Note:&quot;Similar to TRMT1L TRMT1-like protein (Macaca fascicularis)&quot; offset:0 AED:0.30 eAED:0.30 QI:0|0.47|0.54|0.54|0.80|0.72|22|0|607</Iteration_query-def>
  <Iteration_query-len>1824</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDR120C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:691549:693261:-1 gene:YDR120C transcript:YDR120C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TRM1 description:tRNA methyltransferase; two forms of protein are made by alternative translation starts; localizes to both nucleus and mitochondrion to produce modified base N2,N2-dimethylguanosine in tRNAs in both compartments; nuclear Trm1p is evenly distributed around inner nuclear membrane in WT, but mislocalizes as puncta near ER-nucleus junctions in spindle pole body (SPB) mutants; both Trm1p inner nuclear membrane targeting and maintenance depend upon SPB [Source:SGD;Acc:S000002527]</Hit_def>
  <Hit_accession>YDR120C</Hit_accession>
  <Hit_len>570</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>3.93922e-07</Hsp_evalue>
      <Hsp_query-from>1309</Hsp_query-from>
      <Hsp_query-to>1743</Hsp_query-to>
      <Hsp_hit-from>134</Hsp_hit-from>
      <Hsp_hit-to>279</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>147</Hsp_align-len>
      <Hsp_qseq>LACLDAFGATGIMGLQWAKHLGNTVRVTINDVSEASVRMMEENCRLNGMTVTESWPDSDXXXXXXXXXXXDRLVEVTHHLDPFGTAVDYLDAAFRNVRNHGIVSITSTDLSSLYCK-VPNVALRHY-HCNLVRTEYYHELAARMVLT</Hsp_qseq>
      <Hsp_hseq>INILEALSATGLRAIRYAHEIPHVREVIANDLLPEAVESIKRNVEYNSVENIVKPNLDDANVLMYRNKATNNKFHVID-LDPYGTVTPFVDAAIQSIEEGGLMLVTCTDLSVLAGNGYPEKCFALYGGANMVSHESTHESALRLVLN</Hsp_hseq>
      <Hsp_midline>+  L+A  ATG+  +++A  + +   V  ND+   +V  ++ N   N +         D        +A +    V   LDP+GT   ++DAA +++   G++ +T TDLS L     P      Y   N+V  E  HE A R+VL </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1173265371</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054695-RA transcript Note:&quot;Similar to Wdr24 GATOR complex protein WDR24 (Mus musculus)&quot; offset:0 AED:0.38 eAED:0.40 QI:0|0.57|0.37|1|1|1|8|0|421</Iteration_query-def>
  <Iteration_query-len>1266</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YOL138C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:61325:65350:-1 gene:YOL138C transcript:YOL138C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RTC1 description:Subunit of SEACAT, a subcomplex of the SEA complex; Rtc1p, along with Mtc5p and Sea4p, redundantly inhibit the TORC1 inhibitory role of the Iml1p/SEACIT (Iml1p-Npr2p-Npr3p) subcomplex, a GAP for GTPase Gtr1p (EGOC subunit) in response to amino acid limitation, thereby resulting in activation of TORC1 signaling; SEA is a coatomer-related complex that associates dynamically with the vacuole; has N-terminal WD-40 repeats and a C-terminal RING motif; null suppresses cdc13-1 [Source:SGD;Acc:S000005498]</Hit_def>
  <Hit_accession>YOL138C</Hit_accession>
  <Hit_len>1341</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>1.56248e-08</Hsp_evalue>
      <Hsp_query-from>319</Hsp_query-from>
      <Hsp_query-to>666</Hsp_query-to>
      <Hsp_hit-from>226</Hsp_hit-from>
      <Hsp_hit-to>381</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>156</Hsp_align-len>
      <Hsp_qseq>LATAATNGAVLTWNLGKASRNKQELL--FAEHKRTVNRVCFHPSELHMLLSGSQDGFMK--------------------CQSESVRDVQFSP------------------RDCFSFAATFENGNVQLWDIRRSDRAERMFTAHNGPVFTCDWHPDE</Hsp_qseq>
      <Hsp_hseq>IAVCNNSTAISIYDLNKSSSIDNPLITSLCEHTRSINSFDFNMVESNLIISGGQDSCVKIWDLRSNKSKSSNRSDISINTASDSIRDVKWMPGYNFASKNDQGSSTYGNLKSGYKFASIHDSGYLLKFDLRQPAQYEKKLNAHTGPGLCLNWHPNQ</Hsp_hseq>
      <Hsp_midline>+A    + A+  ++L K+S     L+    EH R++N   F+  E ++++SG QD  +K                      S+S+RDV++ P                  +  + FA+  ++G +  +D+R+  + E+   AH GP    +WHP++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YNL317W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:40619:42016:1 gene:YNL317W transcript:YNL317W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PFS2 description:Integral subunit of the pre-mRNA CPF complex; the cleavage and polyadenylation factor (CPF) complex plays an essential role in mRNA 3&apos;-end formation by bridging different processing factors and thereby promoting the assembly of the processing complex [Source:SGD;Acc:S000005261]</Hit_def>
  <Hit_accession>YNL317W</Hit_accession>
  <Hit_len>465</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>7.29754e-08</Hsp_evalue>
      <Hsp_query-from>319</Hsp_query-from>
      <Hsp_query-to>804</Hsp_query-to>
      <Hsp_hit-from>108</Hsp_hit-from>
      <Hsp_hit-to>292</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>194</Hsp_align-len>
      <Hsp_qseq>LATAATNGAVLTWNLGKASRNKQELLFAEHKRTVNRVCF-HPSELHMLLSGSQDGFMKC--------------QSESVRDVQFSPRDCFSFAATFENGNVQLWDIRRSDRAERMFTAHNGPVFTCDWHPDESARA-------------REQYCVQTIA----SVARVKWRPERRHHLATCSMMVDHSVSVWDVR</Hsp_qseq>
      <Hsp_hseq>LVVATYSGEFSLWN---ASSFTFETLMQAHDSAVTTMKYSHDSDW--MISGDADGMIKIWQPNFSMVKEIDAAHTESIRDMAFSSNDS-KFVTCSDDNILKIWNFSNG-KQERVLSGHHWDVKSCDWHPEMGLIASASKDNLVKLWDPRSGNCISSILKFKHTVLKTRFQPTKGNLLMAISK--DKSCRVFDIR</Hsp_hseq>
      <Hsp_midline>L  A  +G    WN   AS    E L   H   V  + + H S+   ++SG  DG +K                +ES+RD+ FS  D   F    ++  +++W+     + ER+ + H+  V +CDWHP+    A             R   C+ +I     +V + +++P + + L   S   D S  V+D+R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YDR128W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:709549:712995:1 gene:YDR128W transcript:YDR128W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MTC5 description:Subunit of SEACAT, a subcomplex of the SEA complex; Mtc1p, along with Rtc1p and Sea4p, redundantly inhibit the TORC1 inhibitory role of the Iml1p/SEACIT (Iml1p-Npr2p-Npr3p) subcomplex, a GAP for GTPase Gtr1p (EGOC subunit) in response to amino acid limitation, thereby resulting in activation of TORC1 signaling; SEA is a coatomer-related complex that associates dynamically with the vacuole; relative distribution to the vacuolar membrane decreases upon DNA replication stress [Source:SGD;Acc:S000002535]</Hit_def>
  <Hit_accession>YDR128W</Hit_accession>
  <Hit_len>1148</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>8.69897e-07</Hsp_evalue>
      <Hsp_query-from>103</Hsp_query-from>
      <Hsp_query-to>486</Hsp_query-to>
      <Hsp_hit-from>16</Hsp_hit-from>
      <Hsp_hit-to>139</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>130</Hsp_align-len>
      <Hsp_qseq>GRTMSISLDGPANALSVCRDGSQVAVAGRNVFKLYAIEDGEFVERANLRVGRKPSLNYSCADVAW--HQMDDSLLATAATNGAVLTWNLGKASRNKQELLFAEHKRTVNRVCFHPSELHMLLSGSQDGFM</Hsp_qseq>
      <Hsp_hseq>GKSLSLKVDGGFNAVSINPSGRDIVLASRQGLYIIDLDDPFTPPRWLHHITP-----WQVADVQWSPHPAKPYWIVSTSNQKAII-WNLAKSSSNAIEFVLHGHSRAITDINFNPQHPDVLATCSVDTYV</Hsp_hseq>
      <Hsp_midline>G+++S+ +DG  NA+S+   G  + +A R    +  ++D     R    +       +  ADV W  H      + + +   A++ WNL K+S N  E +   H R +  + F+P    +L + S D ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YNL006W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:620067:620978:1 gene:YNL006W transcript:YNL006W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:LST8 description:Protein required for the transport of Gap1p; required for the transport of amino acid permease Gap1p from the Golgi to the cell surface; component of the TOR signaling pathway; associates with both Tor1p and Tor2p; contains a WD-repeat [Source:SGD;Acc:S000004951]</Hit_def>
  <Hit_accession>YNL006W</Hit_accession>
  <Hit_len>303</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>1.12802e-06</Hsp_evalue>
      <Hsp_query-from>127</Hsp_query-from>
      <Hsp_query-to>906</Hsp_query-to>
      <Hsp_hit-from>32</Hsp_hit-from>
      <Hsp_hit-to>271</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>52</Hsp_gaps>
      <Hsp_align-len>276</Hsp_align-len>
      <Hsp_qseq>DGPANALSVCRDGSQVAVAGRNVFKLYAIEDGEFVERANLRVGRKPSLNYSCADVAWHQMDDSLLATAATNGAVLTWNLGKAS--RNKQELLFAEHKRTVNRVCFHPSELHMLLSGSQDGFMKCQS--ESVRDVQFSPRDCFSF------------AATFENGNVQLWDIRRSDRAERMFTAHNGPVFTCDWHPDESARAREQYCVQTIASVARVKWRPERRHHLATCSMMVDHSVSVWDVRRPYIPFAAFPEHRDVTTGIAWRNDPHYLLSGSKD</Hsp_qseq>
      <Hsp_hseq>DSQVNRLEITNDKKLLATAGHQNVRLYDIRTTNPNPVASFEGHRGNVTSVS------FQQDNRWMVTSSEDGTIKVWDVRSPSIPRNYK------HNAPVNEVVIHPNQGE-LISCDRDGNIRIWDLGENQCTHQLTPEDDTSLQSLSMASDGSMLAAANTKGNCYVWEMPNHTDASHL-------------KPVTKFRAHSTYITRILLS-SDVK-------HLATCS--ADHTARVWSIDDDFKLETTLDGHQRWVWDCAFSADSAYLVTASSD</Hsp_hseq>
      <Hsp_midline>D   N L +  D   +A AG    +LY I        A+    R    + S       Q D+  + T++ +G +  W++   S  RN +      H   VN V  HP++   L+S  +DG ++     E+    Q +P D  S             AA    GN  +W++     A  +              P    RA   Y  + + S + VK       HLATCS   DH+  VW +   +        H+      A+  D  YL++ S D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>92</Statistics_hsp-len>
      <Statistics_eff-space>761266110</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054696-RA transcript Note:&quot;Similar to PGLS 6-phosphogluconolactonase (Bos taurus)&quot; offset:86 AED:0.03 eAED:0.03 QI:86|1|1|1|0|0.4|5|1543|246</Iteration_query-def>
  <Iteration_query-len>2370</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YHR163W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:423724:424473:1 gene:YHR163W transcript:YHR163W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SOL3 description:6-phosphogluconolactonase; catalyzes the second step of the pentose phosphate pathway; weak multicopy suppressor of los1-1 mutation; homologous to Sol2p and Sol1p; SOL3 has a paralog, SOL4, that arose from the whole genome duplication [Source:SGD;Acc:S000001206]</Hit_def>
  <Hit_accession>YHR163W</Hit_accession>
  <Hit_len>249</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>120.939</Hsp_bit-score>
      <Hsp_score>302</Hsp_score>
      <Hsp_evalue>3.4185e-31</Hsp_evalue>
      <Hsp_query-from>213</Hsp_query-from>
      <Hsp_query-to>773</Hsp_query-to>
      <Hsp_hit-from>39</Hsp_hit-from>
      <Hsp_hit-to>230</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>201</Hsp_align-len>
      <Hsp_qseq>LSGGSVVAAXXXX----XXXXXXXXWARTRLLFCDERLVPHHHPDSTYGQYKASLLGKVP-LPESHVVAINPSL------SVEEAAQDYERRMREVFPGEDIPVFDLLVLGMGPDGHTCSLFPSHP---LLQETKLLVAPISDSPKPPPERITLTLPVINAARCVMFISTGESKAAILKQVLEGHDEHPLPAALVQPSNGE</Hsp_qseq>
      <Hsp_hseq>VSGGSLIDALYESLVADESLSSRVQWSKWQIYFSDERIVPLTDADSNYGAFKRAVLDKLPSTSQPNVYPMDESLIGSDAESNNKIAAEYER----IVP----QVLDLVLLGCGPDGHTCSLFPGETHRYLLNETTKRVAWCHDSPKPPSDRITFTLPVLKDAKALCFVAEGSSKQNIMHEIFDLKNDQ-LPTALVNKLFGE</Hsp_hseq>
      <Hsp_midline>+SGGS++ AL             + W++ ++ F DER+VP    DS YG +K ++L K+P   + +V  ++ SL      S  + A +YER    + P     V DL++LG GPDGHTCSLFP      LL ET   VA   DSPKPP +RIT TLPV+  A+ + F++ G SK  I+ ++ +  ++  LP ALV    GE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YGR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:985972:986739:1 gene:YGR248W transcript:YGR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SOL4 description:6-phosphogluconolactonase; protein abundance increases in response to DNA replication stress; SOL4 has a paralog, SOL3, that arose from the whole genome duplication [Source:SGD;Acc:S000003480]</Hit_def>
  <Hit_accession>YGR248W</Hit_accession>
  <Hit_len>255</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>106.301</Hsp_bit-score>
      <Hsp_score>264</Hsp_score>
      <Hsp_evalue>4.67878e-26</Hsp_evalue>
      <Hsp_query-from>276</Hsp_query-from>
      <Hsp_query-to>770</Hsp_query-to>
      <Hsp_hit-from>66</Hsp_hit-from>
      <Hsp_hit-to>236</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>176</Hsp_align-len>
      <Hsp_qseq>WARTRLLFCDERLVPHHHPDSTYGQYKASLLGKVPLPES--------HVVAINPSLSVEEAAQDYERRMREVFPGEDIPVFDLLVLGMGPDGHTCSLFPS---HPLLQETKLLVAPISDSPKPPPERITLTLPVINAARCVMFISTGESKAAILKQVLEGHDEHPLPAALVQPSNG</Hsp_qseq>
      <Hsp_hseq>WPQWRIFFCDERLVPFEDPQSNYGQFKKTVLD--PLVHQGNQLNLGPTVYTINESLI--GGGETANRKIAEEYASMLPASFDLILLGCGEDGHTCSLFPGVEFNYLVEEMDRKVLWCNNSPKAPKDRITFTLAVVAEAKSVCFLVRGAAKKAIMHDVLIVKNSE-LPSVLVNEMVG</Hsp_hseq>
      <Hsp_midline>W + R+ FCDERLVP   P S YGQ+K ++L   PL            V  IN SL      +   R++ E +       FDL++LG G DGHTCSLFP    + L++E    V   ++SPK P +RIT TL V+  A+ V F+  G +K AI+  VL   +   LP+ LV    G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YNR034W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:690321:691286:1 gene:YNR034W transcript:YNR034W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SOL1 description:Protein with a possible role in tRNA export; shows similarity to 6-phosphogluconolactonase non-catalytic domains but does not exhibit this enzymatic activity; homologous to Sol3p and Sol4p; SOL1 has a paralog, SOL2, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005317]</Hit_def>
  <Hit_accession>YNR034W</Hit_accession>
  <Hit_len>321</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>106.301</Hsp_bit-score>
      <Hsp_score>264</Hsp_score>
      <Hsp_evalue>1.47803e-25</Hsp_evalue>
      <Hsp_query-from>213</Hsp_query-from>
      <Hsp_query-to>782</Hsp_query-to>
      <Hsp_hit-from>96</Hsp_hit-from>
      <Hsp_hit-to>294</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>200</Hsp_align-len>
      <Hsp_qseq>LSGGSVVAAXXXXXXXXXXXXWARTRLLFCDERLVPHHHPDSTYGQYKASLLGKVPLPES---HVVAINPSL--SVEEAAQDYERRMREVFPGED---IPVFDLLVLGMGPDGHTCSLFPS-HPLLQETKLLVAPISDSPKPPPERITLTLPVINAARCVMFISTGESKAAILKQVLEGHDEHPLPAALV-QPSNGELLW</Hsp_qseq>
      <Hsp_hseq>LSGGSLIQVLHEGLLKRDDVQWGKWDIYFADERLVPFSSSESNYGLAKRKIFDLIDTEKYGTPKIYHIDESLINDPQECADNYEKILIKGFAGRDSVKLPMFDLFLLGCAPDGHIASLFPNFQENLRENLAWVIPVENAPSGPSNRISLTIPVICHSHRVTFVVEGATKAPVIKTIME-RPEKGLPSSIVNEGAAGRVSW</Hsp_hseq>
      <Hsp_midline>LSGGS++  L   L     + W +  + F DERLVP    +S YG  K  +   +   +     +  I+ SL    +E A +YE+ + + F G D   +P+FDL +LG  PDGH  SLFP+    L+E    V P+ ++P  P  RI+LT+PVI  +  V F+  G +KA ++K ++E   E  LP+++V + + G + W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YCR073W-A</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:246963:247910:1 gene:YCR073W-A transcript:YCR073W-A_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SOL2 description:Protein with a possible role in tRNA export; shows similarity to 6-phosphogluconolactonase non-catalytic domains but does not exhibit this enzymatic activity; homologous to Sol3p and Sol4p; SOL2 has a paralog, SOL1, that arose from the whole genome duplication [Source:SGD;Acc:S000000718]</Hit_def>
  <Hit_accession>YCR073W-A</Hit_accession>
  <Hit_len>315</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>105.531</Hsp_bit-score>
      <Hsp_score>262</Hsp_score>
      <Hsp_evalue>2.6349e-25</Hsp_evalue>
      <Hsp_query-from>213</Hsp_query-from>
      <Hsp_query-to>782</Hsp_query-to>
      <Hsp_hit-from>92</Hsp_hit-from>
      <Hsp_hit-to>290</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>200</Hsp_align-len>
      <Hsp_qseq>LSGGSVVAAXXXXXXXXXXXXWARTRLLFCDERLVPHHHPDSTYGQYKASLLGKVPLPES---HVVAINPSL--SVEEAAQDYERRMREVFPGED---IPVFDLLVLGMGPDGHTCSLFPS-HPLLQETKLLVAPISDSPKPPPERITLTLPVINAARCVMFISTGESKAAILKQVLEGHDEHPLPAALV-QPSNGELLW</Hsp_qseq>
      <Hsp_hseq>LSGGSLIEVLHEGLLKRDDVRWGDWDIYFADERLVPFSSNESNYGCAKRKILDLIDTAKYGTPKVYHIDESLIDDPQECADNYEKVLIRGFAGRDSVKLPMFDLFLLGCAPDGHIASLFPNFQDNLREKLAWVVPVENAPSGPSTRISLTIPVICHSHRVTFVVEGATKAPIIKTIME-RPEKGLPSSIVNEGAAGRVSW</Hsp_hseq>
      <Hsp_midline>LSGGS++  L   L     + W    + F DERLVP    +S YG  K  +L  +   +     V  I+ SL    +E A +YE+ +   F G D   +P+FDL +LG  PDGH  SLFP+    L+E    V P+ ++P  P  RI+LT+PVI  +  V F+  G +KA I+K ++E   E  LP+++V + + G + W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1575789831</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

