<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0057097-RA transcript Note:&quot;Similar to PPARD Peroxisome proliferator-activated receptor delta (Homo sapiens)&quot; offset:0 AED:0.31 eAED:0.31 QI:0|0.4|0.33|1|1|1|6|0|394</BlastOutput_query-def>
  <BlastOutput_query-len>1185</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057097-RA transcript Note:&quot;Similar to PPARD Peroxisome proliferator-activated receptor delta (Homo sapiens)&quot; offset:0 AED:0.31 eAED:0.31 QI:0|0.4|0.33|1|1|1|6|0|394</Iteration_query-def>
  <Iteration_query-len>1185</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>92</Statistics_hsp-len>
      <Statistics_eff-space>698980701</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057099-RA transcript Note:&quot;Similar to alphaTub84B Tubulin alpha-1 chain (Drosophila melanogaster)&quot; offset:100 AED:0.27 eAED:0.27 QI:100|0.62|0.77|1|0.75|0.77|9|2711|701</Iteration_query-def>
  <Iteration_query-len>4917</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YML085C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:97941:99400:-1 gene:YML085C transcript:YML085C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TUB1 description:Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules; relative distribution to nuclear foci increases upon DNA replication stress; TUB1 has a paralog, TUB3, that arose from the whole genome duplication [Source:SGD;Acc:S000004550]</Hit_def>
  <Hit_accession>YML085C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>672.929</Hsp_bit-score>
      <Hsp_score>1735</Hsp_score>
      <Hsp_evalue>0</Hsp_evalue>
      <Hsp_query-from>857</Hsp_query-from>
      <Hsp_query-to>2143</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>431</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>325</Hsp_identity>
      <Hsp_positive>373</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>430</Hsp_align-len>
      <Hsp_qseq>RECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTI-GGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRSGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADQCTGLQGFLIFHXXXXXXXXXXXXXXMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSVLTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPVISAEKAYHEQLSVSEITNSCFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTAVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEK</Hsp_qseq>
      <Hsp_hseq>REVISINVGQAGCQIGNACWELYSLEHGIKPDGHLEDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRNGPYKDLFHPEQLISGKEDAANNYARGHYTVGREILGDVLDRIRKLADQCDGLQGFLFTHSLGGGTGSGLGSLLLEELSAEYGKKSKLEFAVYPAPQVSTSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDMCKRNLDIPRPSFANLNNLIAQVVSSVTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYSPVLSKSKAFHESNSVSEITNACFEPGNQMVKCDPRDGKYMATCLLYRGDVVTRDVQRAVEQVKNKKTVQLVDWCPTGFKIGICYEPPTATPNSQLATVDRAVCMLSNTTSIAEAWKRIDRKFDLMYAKRAFVHWYVGEGMEEGEFTEAREDLAALER</Hsp_hseq>
      <Hsp_midline>RE ISI+VGQAG QIGNACWELY LEHGI+PDG +    +   GG++ F+TFF ETG GK VPRA++VDLEP V+DEVR+G Y+ LFHPEQLI+GKEDAANNYARGHYT+G+EI+  VLDRIRKLADQC GLQGFL  HS GGGTGSG  +LL+E LS +YGKKSKLEFA+YPAPQVST+VVEPYN+VLTTHTTLEH+DC FMVDNEAIYD+C+RNLDI RP++ NLN LI Q+VSS+TASLRFDG+LNVDL EFQTNLVPYPRIHFPLV+Y+PV+S  KA+HE  SVSEITN+CFEP NQMVKCDPR GKYMA C+LYRGDVV +DV  A+  +K K+++Q VDWCPTGFK+GI Y+PPTA P   LA V RAVCMLSNTT+IAEAW R+D KFDLMYAKRAFVHWYVGEGMEEGEF+EAREDLAALE+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>188.348</Hsp_bit-score>
      <Hsp_score>477</Hsp_score>
      <Hsp_evalue>5.86684e-52</Hsp_evalue>
      <Hsp_query-from>59</Hsp_query-from>
      <Hsp_query-to>430</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>126</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>88</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>125</Hsp_align-len>
      <Hsp_qseq>RECISIHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTI-GGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKL</Hsp_qseq>
      <Hsp_hseq>REVISINVGQAGCQIGNACWELYSLEHGIKPDGHLEDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRNGPYKDLFHPEQLISGKEDAANNYARGHYTVGREILGDVLDRIRKL</Hsp_hseq>
      <Hsp_midline>RE ISI+VGQAG Q+GNACWELY LEHGI+PDG +    +   GG++ F+TFF ETG GK VPRA++VDLEP V+DEVR G Y+ LFHPEQLI+GKEDAANNYARGHYT+G+EI+  VLDRIRKL</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>162.925</Hsp_bit-score>
      <Hsp_score>411</Hsp_score>
      <Hsp_evalue>3.15312e-43</Hsp_evalue>
      <Hsp_query-from>428</Hsp_query-from>
      <Hsp_query-to>802</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>126</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>85</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>128</Hsp_align-len>
      <Hsp_qseq>LRECISIHVGQAGVQMGNACWELYCLEHGIQPDGQMPCHDNIG---GXXXXXXXXXXXXXXXKYVPRAIFVDLEPTVVDEIRTGTYRQLYHPEQMITGKEDAANNYARGHYTIGKEIVDLVLDRIRKL</Hsp_qseq>
      <Hsp_hseq>MREVISINVGQAGCQIGNACWELYSLEHGIKPDGHL--EDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRNGPYKDLFHPEQLISGKEDAANNYARGHYTVGREILGDVLDRIRKL</Hsp_hseq>
      <Hsp_midline>+RE ISI+VGQAG Q+GNACWELY LEHGI+PDG +   D +    G    FSTFF ET   K+VPRAI+VDLEP V+DE+R G Y+ L+HPEQ+I+GKEDAANNYARGHYT+G+EI+  VLDRIRKL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YML124C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:22048:23683:-1 gene:YML124C transcript:YML124C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TUB3 description:Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules; expressed at lower level than Tub1p; TUB3 has a paralog, TUB1, that arose from the whole genome duplication [Source:SGD;Acc:S000004593]</Hit_def>
  <Hit_accession>YML124C</Hit_accession>
  <Hit_len>445</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>666.766</Hsp_bit-score>
      <Hsp_score>1719</Hsp_score>
      <Hsp_evalue>0</Hsp_evalue>
      <Hsp_query-from>857</Hsp_query-from>
      <Hsp_query-to>2143</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>431</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>316</Hsp_identity>
      <Hsp_positive>372</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>430</Hsp_align-len>
      <Hsp_qseq>RECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTI-GGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRSGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADQCTGLQGFLIFHXXXXXXXXXXXXXXMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSVLTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPVISAEKAYHEQLSVSEITNSCFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTAVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEK</Hsp_qseq>
      <Hsp_hseq>REVISINVGQAGCQIGNACWELYSLEHGIKEDGHLEDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRTGRFKELFHPEQLINGKEDAANNYARGHYTVGREIVDEVEERIRKMADQCDGLQGFLFTHSLGGGTGSGLGSLLLENLSYEYGKKSKLEFAVYPAPQLSTSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDICKRNLGISRPSFSNLNGLIAQVISSVTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYAPILSKKRATHESNSVSEITNACFEPGNQMVKCDPTKGKYMANCLLYRGDVVTRDVQRAVEQVKNKKTVQMVDWCPTGFKIGICYEPPSVIPSSELANVDRAVCMLSNTTAIADAWKRIDQKFDLMYAKRAFVHWYVGEGMEEGEFTEAREDLAALER</Hsp_hseq>
      <Hsp_midline>RE ISI+VGQAG QIGNACWELY LEHGI+ DG +    +   GG++ F+TFF ETG GK VPRA++VDLEP V+DEVR+G +++LFHPEQLI GKEDAANNYARGHYT+G+EIVD V +RIRK+ADQC GLQGFL  HS GGGTGSG  +LL+E LS +YGKKSKLEFA+YPAPQ+ST+VVEPYN+VLTTHTTLEH+DC FMVDNEAIYDIC+RNL I RP+++NLN LI Q++SS+TASLRFDG+LNVDL EFQTNLVPYPRIHFPLV+YAP++S ++A HE  SVSEITN+CFEP NQMVKCDP  GKYMA C+LYRGDVV +DV  A+  +K K+++Q VDWCPTGFK+GI Y+PP+ +P  +LA V RAVCMLSNTTAIA+AW R+D KFDLMYAKRAFVHWYVGEGMEEGEF+EAREDLAALE+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>185.652</Hsp_bit-score>
      <Hsp_score>470</Hsp_score>
      <Hsp_evalue>6.08941e-51</Hsp_evalue>
      <Hsp_query-from>59</Hsp_query-from>
      <Hsp_query-to>430</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>126</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>86</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>125</Hsp_align-len>
      <Hsp_qseq>RECISIHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTI-GGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKL</Hsp_qseq>
      <Hsp_hseq>REVISINVGQAGCQIGNACWELYSLEHGIKEDGHLEDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRTGRFKELFHPEQLINGKEDAANNYARGHYTVGREIVDEVEERIRKM</Hsp_hseq>
      <Hsp_midline>RE ISI+VGQAG Q+GNACWELY LEHGI+ DG +    +   GG++ F+TFF ETG GK VPRA++VDLEP V+DEVRTG +++LFHPEQLI GKEDAANNYARGHYT+G+EIVD V +RIRK+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>159.458</Hsp_bit-score>
      <Hsp_score>402</Hsp_score>
      <Hsp_evalue>3.86535e-42</Hsp_evalue>
      <Hsp_query-from>428</Hsp_query-from>
      <Hsp_query-to>802</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>126</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>83</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>128</Hsp_align-len>
      <Hsp_qseq>LRECISIHVGQAGVQMGNACWELYCLEHGIQPDGQMPCHDNIG---GXXXXXXXXXXXXXXXKYVPRAIFVDLEPTVVDEIRTGTYRQLYHPEQMITGKEDAANNYARGHYTIGKEIVDLVLDRIRKL</Hsp_qseq>
      <Hsp_hseq>MREVISINVGQAGCQIGNACWELYSLEHGIKEDGHL--EDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRTGRFKELFHPEQLINGKEDAANNYARGHYTVGREIVDEVEERIRKM</Hsp_hseq>
      <Hsp_midline>+RE ISI+VGQAG Q+GNACWELY LEHGI+ DG +   D +    G    FSTFF ET   K+VPRAI+VDLEP V+DE+RTG +++L+HPEQ+I GKEDAANNYARGHYT+G+EIVD V +RIRK+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YFL037W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:56336:57709:1 gene:YFL037W transcript:YFL037W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TUB2 description:Beta-tubulin; associates with alpha-tubulin (Tub1p and Tub3p) to form tubulin dimer, which polymerizes to form microtubules; mutation in human ortholog is associated with congenital fibrosis of the extraocular muscles (CFEOM) with polymicrogyria [Source:SGD;Acc:S000001857]</Hit_def>
  <Hit_accession>YFL037W</Hit_accession>
  <Hit_len>457</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>341.273</Hsp_bit-score>
      <Hsp_score>874</Hsp_score>
      <Hsp_evalue>9.01194e-105</Hsp_evalue>
      <Hsp_query-from>857</Hsp_query-from>
      <Hsp_query-to>2137</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>418</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>178</Hsp_identity>
      <Hsp_positive>257</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>431</Hsp_align-len>
      <Hsp_qseq>RECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDD----SFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRSGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADQCTGLQGFLIFHXXXXXXXXXXXXXXMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSVLTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPVISAEKAYHEQLSVSEITNSCFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTAVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAAL</Hsp_qseq>
      <Hsp_hseq>REIIHISTGQCGNQIGAAFWETICGEHGLDFNG------TYHGHDDIQKERLNVYFNEASSGKWVPRSINVDLEPGTIDAVRNSAIGNLFRPDNYIFGQSSAGNVWAKGHYTEGAELVDSVMDVIRREAEGCDSLQGFQITHSLGGGTGSGMGTLLISKIREEFPDRMMATFSVLPSPKTSDTVVEPYNATLSVHQLVEHSDETFCIDNEALYDICQRTLKLNQPSYGDLNNLVSSVMSGVTTSLRYPGQLNSDLRKLAVNLVPFPRLHFFMVGYAPLTAIGSQSFRSLTVPELTQQMFDAKNMMAAADPRNGRYLTVAAFFRGKVSVKEVEDEMHKVQSKNSDYFVEWIPNNVQTAV----CSVAPQG----LDMAATFIANSTSIQELFKRVGDQFSAMFKRKAFLHWYTSEGMDELEFSEAESNMNDL</Hsp_hseq>
      <Hsp_midline>RE I I  GQ G QIG A WE  C EHG+  +G      T  G DD      N +F+E  +GK VPR++ VDLEP  +D VR+     LF P+  I G+  A N +A+GHYT G E+VD V+D IR+ A+ C  LQGF I HS GGGTGSG   LL+ ++  ++  +    F++ P+P+ S  VVEPYN+ L+ H  +EHSD  F +DNEA+YDIC+R L + +P+Y +LN L+  ++S +T SLR+ G LN DL +   NLVP+PR+HF +V YAP+ +        L+V E+T   F+  N M   DPR+G+Y+     +RG V  K+V   +  +++K S  FV+W P   +  +     +  P G    +  A   ++N+T+I E + R+  +F  M+ ++AF+HWY  EGM+E EFSEA  ++  L</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>108.612</Hsp_bit-score>
      <Hsp_score>270</Hsp_score>
      <Hsp_evalue>5.86616e-25</Hsp_evalue>
      <Hsp_query-from>59</Hsp_query-from>
      <Hsp_query-to>451</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>131</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>RECISIHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDD----SFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLRE-CISIH</Hsp_qseq>
      <Hsp_hseq>REIIHISTGQCGNQIGAAFWETICGEHGLDFNG------TYHGHDDIQKERLNVYFNEASSGKWVPRSINVDLEPGTIDAVRNSAIGNLFRPDNYIFGQSSAGNVWAKGHYTEGAELVDSVMDVIRREAEGCDSLQ</Hsp_hseq>
      <Hsp_midline>RE I I  GQ G Q+G A WE  C EHG+  +G      T  G DD      N +F+E  +GK VPR++ VDLEP  +D VR      LF P+  I G+  A N +A+GHYT G E+VD V+D IR+  E C S+ </Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>99.7525</Hsp_bit-score>
      <Hsp_score>247</Hsp_score>
      <Hsp_evalue>4.6564e-22</Hsp_evalue>
      <Hsp_query-from>428</Hsp_query-from>
      <Hsp_query-to>799</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>122</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>124</Hsp_align-len>
      <Hsp_qseq>LRECISIHVGQAGVQMGNACWELYCLEHGIQPDGQMPCHDNIGGXXXXXXXXXXXXXXXKYVPRAIFVDLEPTVVDEIRTGTYRQLYHPEQMITGKEDAANNYARGHYTIGKEIVDLVLDRIRK</Hsp_qseq>
      <Hsp_hseq>MREIIHISTGQCGNQIGAAFWETICGEHGLDFNGTYHGHDDI--QKERLNVYFNEASSGKWVPRSINVDLEPGTIDAVRNSAIGNLFRPDNYIFGQSSAGNVWAKGHYTEGAELVDSVMDVIRR</Hsp_hseq>
      <Hsp_midline>+RE I I  GQ G Q+G A WE  C EHG+  +G    HD+I       + +F+E S+ K+VPR+I VDLEP  +D +R      L+ P+  I G+  A N +A+GHYT G E+VD V+D IR+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YLR212C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:564860:566281:-1 gene:YLR212C transcript:YLR212C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TUB4 description:Gamma-tubulin; involved in nucleating microtubules from both the cytoplasmic and nuclear faces of the spindle pole body; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004202]</Hit_def>
  <Hit_accession>YLR212C</Hit_accession>
  <Hit_len>473</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>169.088</Hsp_bit-score>
      <Hsp_score>427</Hsp_score>
      <Hsp_evalue>4.72387e-45</Hsp_evalue>
      <Hsp_query-from>860</Hsp_query-from>
      <Hsp_query-to>2137</Hsp_query-to>
      <Hsp_hit-from>4</Hsp_hit-from>
      <Hsp_hit-to>433</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>131</Hsp_identity>
      <Hsp_positive>217</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>444</Hsp_align-len>
      <Hsp_qseq>ECISIHVGQAGVQIGNACWELYCLEHGIQPDG--QMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRSGTYRQLFHPEQLITGKE--DAANNYARGHYTIGKEIVDLVLDRIRKLADQCTGLQGFLIFHXXXXXXXXXXXXXXMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSVLTTHTTLEHSDCAFMVDNEAIYDICRR-----NLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPVISA---EKAYHEQLSVSEITNSCFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTAVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWY-VGEGME-----EGEFSEAREDLAAL</Hsp_qseq>
      <Hsp_hseq>EIITLQAGQCGNHVGKFLWSQLAKEHAIGTDGLSQLPDSST--ERDDDTKPFFRENSRNKFTPRAIMMDSEPSVIADVEN-TFRGFFDPRNTWVASDGASAGNSWANG-YDIGTRNQDDILNKIDKEIDSTDNFEGFQLLHSVAGGTGSGLGSNLLEALCDRYPKKILTTYSVFPA-RSSEVVVQSYNTILALRRLIEDSDATVVFDNASLLNISGKVFRNPNIDLQH-----TNQLISTIISSVTNSIRFPSYMYSSMSSIYSTLIPSPELHFLSPSFTPFTSDYIHDDIAHKGHSSYDVMLDLLDPSNSLVSTAMNNPTYFNVYNTIIGNVEPRQISRAMT--KLQQRIKFPSWSSSAMHVNIGRRSPYLPLQPNENEV--SGMMLSNMSTVVNVFENACNTFDKVFAKGAFLNNYNVGDLFQSMQNVQDEFAESREVVQSL</Hsp_hseq>
      <Hsp_midline>E I++  GQ G  +G   W     EH I  DG  Q+P   T    DD    FF E    K  PRA+ +D EP+V+ +V + T+R  F P       +   A N++A G Y IG    D +L++I K  D     +GF + HS  GGTGSG  + L+E L   Y KK    ++++PA + S  VV+ YN++L     +E SD   + DN ++ +I  +     N+D++       N+LI  I+SS+T S+RF   +   ++   + L+P P +HF   ++ P  S    +   H+  S  ++     +P+N +V     +  Y        G+V P+ ++ A+   K ++ I+F  W  +   V I  + P      +  +V  +  MLSN + +   +    + FD ++AK AF++ Y VG+  +     + EF+E+RE + +L</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>1.76745e-12</Hsp_evalue>
      <Hsp_query-from>62</Hsp_query-from>
      <Hsp_query-to>427</Hsp_query-to>
      <Hsp_hit-from>4</Hsp_hit-from>
      <Hsp_hit-to>125</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>126</Hsp_align-len>
      <Hsp_qseq>ECISIHVGQAGVQMGNACWELYCLEHGIQPDG--QMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKE--DAANNYARGHYTIGKEIVDLVLDRIRK</Hsp_qseq>
      <Hsp_hseq>EIITLQAGQCGNHVGKFLWSQLAKEHAIGTDGLSQLPDSST--ERDDDTKPFFRENSRNKFTPRAIMMDSEPSVIADVE-NTFRGFFDPRNTWVASDGASAGNSWANG-YDIGTRNQDDILNKIDK</Hsp_hseq>
      <Hsp_midline>E I++  GQ G  +G   W     EH I  DG  Q+P   T    DD    FF E    K  PRA+ +D EP+V+ +V   T+R  F P       +   A N++A G Y IG    D +L++I K</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>9.28179e-09</Hsp_evalue>
      <Hsp_query-from>434</Hsp_query-from>
      <Hsp_query-to>799</Hsp_query-to>
      <Hsp_hit-from>4</Hsp_hit-from>
      <Hsp_hit-to>125</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>124</Hsp_align-len>
      <Hsp_qseq>ECISIHVGQAGVQMGNACWELYCLEHGIQPDGQMPCHDNIGGXXXXXXXXXXXXXXXKYVPRAIFVDLEPTVVDEIRTGTYRQLYHPEQMITGKE--DAANNYARGHYTIGKEIVDLVLDRIRK</Hsp_qseq>
      <Hsp_hseq>EIITLQAGQCGNHVGKFLWSQLAKEHAIGTDGLSQLPDSSTERDDDTKPFFRENSRNKFTPRAIMMDSEPSVIADVE-NTFRGFFDPRNTWVASDGASAGNSWANG-YDIGTRNQDDILNKIDK</Hsp_hseq>
      <Hsp_midline>E I++  GQ G  +G   W     EH I  DG     D+          FF E S +K+ PRAI +D EP+V+ ++   T+R  + P       +   A N++A G Y IG    D +L++I K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3431834112</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057100-RA transcript Note:&quot;Similar to HDHD5 Haloacid dehalogenase-like hydrolase domain-containing 5 (Homo sapiens)&quot; offset:210 AED:0.36 eAED:0.36 QI:210|0.66|0.5|1|0.66|0.75|4|0|181</Iteration_query-def>
  <Iteration_query-len>756</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YKR070W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:573574:574632:1 gene:YKR070W transcript:YKR070W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [Source:SGD;Acc:S000001778]</Hit_def>
  <Hit_accession>YKR070W</Hit_accession>
  <Hit_len>352</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>3.23701e-13</Hsp_evalue>
      <Hsp_query-from>310</Hsp_query-from>
      <Hsp_query-to>672</Hsp_query-to>
      <Hsp_hit-from>8</Hsp_hit-from>
      <Hsp_hit-to>124</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>122</Hsp_align-len>
      <Hsp_qseq>KTQSASFGLLFDIDGVLVRGRTPIPAARDAFRKLLDASGALRVPVVFVTNAGNCLRQAKAAQLSDVLGVPISQEQVMLSHSPLRMFEQYHHKHVLVSGQGPVEDIAKNLGFTQIV-TIDMLR</Hsp_qseq>
      <Hsp_hseq>QTTSKKIAFAFDIDGVLFRGKKPIAGASDAL-KLLNRN---KIPYILLTNGGGFSERARTEFISSKLDVDVSPLQIIQSHTPYKSLVN-KYSRILAVGTPSVRGVAEGYGFQDVVHQTDIVR</Hsp_hseq>
      <Hsp_midline>+T S      FDIDGVL RG+ PI  A DA  KLL+ +   ++P + +TN G    +A+   +S  L V +S  Q++ SH+P +      +  +L  G   V  +A+  GF  +V   D++R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>87</Statistics_hsp-len>
      <Statistics_eff-space>386078055</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057101-RA transcript Note:&quot;Similar to Hdhd5 Haloacid dehalogenase-like hydrolase domain-containing 5 (Mus musculus)&quot; offset:0 AED:0.36 eAED:0.36 QI:0|0|0|1|0.66|0.25|4|0|268</Iteration_query-def>
  <Iteration_query-len>807</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YKR070W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:573574:574632:1 gene:YKR070W transcript:YKR070W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [Source:SGD;Acc:S000001778]</Hit_def>
  <Hit_accession>YKR070W</Hit_accession>
  <Hit_len>352</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>1.44347e-11</Hsp_evalue>
      <Hsp_query-from>58</Hsp_query-from>
      <Hsp_query-to>351</Hsp_query-to>
      <Hsp_hit-from>196</Hsp_hit-from>
      <Hsp_hit-to>310</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>116</Hsp_align-len>
      <Hsp_qseq>PHLPLLACNMDLMWMAEAKMPRFGHGTFMVCLESIYKKVTGRELKYEALIGKPSEVTYQYAEYLVRTQAREMGWQ------------------NPVKTLYAIGDNPMADIYGANLY</Hsp_qseq>
      <Hsp_hseq>PSIPIYFSNQDLLWANPYKLNRFGQGAFRLLVRRLYLELNGEPLQ-DYTLGKPTKLTYDFAHHVLIDWEKRLSGKIGQSVKQKLPLLGTKPSTSPFHAVFMVGDNPASDIIGAQNY</Hsp_hseq>
      <Hsp_midline>P +P+   N DL+W    K+ RFG G F + +  +Y ++ G  L+ +  +GKP+++TY +A +++    + +  +                  +P   ++ +GDNP +DI GA  Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>88</Statistics_hsp-len>
      <Statistics_eff-space>422321327</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057103-RA transcript Note:&quot;Similar to MIMI_R554 Uncharacterized protein R554 (Acanthamoeba polyphaga mimivirus)&quot; offset:0 AED:0.32 eAED:0.33 QI:0|0|0|0.25|1|1|4|0|767</Iteration_query-def>
  <Iteration_query-len>2304</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1525764757</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0030653-RA transcript Note:&quot;Similar to Wnk1 Serine/threonine-protein kinase WNK1 (Mus musculus)&quot; offset:575 AED:0.15 eAED:0.15 QI:575|0.33|0.25|0.75|0.33|0.25|4|0|385</Iteration_query-def>
  <Iteration_query-len>1733</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.9802</Hsp_bit-score>
      <Hsp_score>110</Hsp_score>
      <Hsp_evalue>4.22456e-06</Hsp_evalue>
      <Hsp_query-from>1443</Hsp_query-from>
      <Hsp_query-to>1712</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>85</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>92</Hsp_align-len>
      <Hsp_qseq>STDGRFLKFDIELGRGSFKTVYKGLDTETGVEVAWCELQDRKLTKAER--QRFKEEAEMLKGLQHPNIVRFYDSWEATVKGRKYIVLVTELM</Hsp_qseq>
      <Hsp_hseq>SSSSQFKQLE-KLGNGTYATVYKGLNKTTGVYVA---LKEVKLDSEEGTPSTAIREISLMKELKHENIVRLYD----VIHTENKLTLVFEFM</Hsp_hseq>
      <Hsp_midline>S+  +F + + +LG G++ TVYKGL+  TGV VA   L++ KL   E        E  ++K L+H NIVR YD     +     + LV E M</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.595</Hsp_bit-score>
      <Hsp_score>109</Hsp_score>
      <Hsp_evalue>9.36651e-06</Hsp_evalue>
      <Hsp_query-from>1479</Hsp_query-from>
      <Hsp_query-to>1706</Hsp_query-to>
      <Hsp_hit-from>61</Hsp_hit-from>
      <Hsp_hit-to>133</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>42</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>77</Hsp_align-len>
      <Hsp_qseq>LGRGSFKTVYKGLDTETGVEVAWCELQDRKLTKAERQ-RFKEEAEMLKGLQHPNIVRFYDSWEATVKGRKYIVLVTE</Hsp_qseq>
      <Hsp_hseq>LGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYD----VIKSKDEIIMVIE</Hsp_hseq>
      <Hsp_midline>LG GSF  V     T TG +VA   +  + L K++ Q R + E   L+ L+HP+I++ YD     +K +  I++V E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1102366294</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0015496-RA transcript Note:&quot;Similar to Wnk3 Serine/threonine-protein kinase WNK3 (Mus musculus)&quot; offset:63 AED:0.12 eAED:0.16 QI:63|0|0|1|1|1|3|0|149</Iteration_query-def>
  <Iteration_query-len>513</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.337</Hsp_bit-score>
      <Hsp_score>194</Hsp_score>
      <Hsp_evalue>2.76282e-18</Hsp_evalue>
      <Hsp_query-from>91</Hsp_query-from>
      <Hsp_query-to>510</Hsp_query-to>
      <Hsp_hit-from>488</Hsp_hit-from>
      <Hsp_hit-to>627</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>144</Hsp_align-len>
      <Hsp_qseq>CRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLA---TLKRASFAKSVIGTPEFMAPEMYEEH-YDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFNKVAFPEVKEIIEGCIRQSKHDR</Hsp_qseq>
      <Hsp_hseq>VKETCQGLKFLHNKK--IIHRDIKSDNILLNS-QGLVKITDFGFCVELTEKRSKRA-TMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANNGSPKLRHPESVSKQTKQFLDACLQVNVESR</Hsp_hseq>
      <Hsp_midline> ++  +GL FLH +   IIHRD+K DNI +    G VK+ D G     T KR+  A +++GTP +MAPE+  +  YDE VDV++ G+ ++EM   E PY        +Y    +G       +    + K+ ++ C++ +   R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.3294</Hsp_bit-score>
      <Hsp_score>181</Hsp_score>
      <Hsp_evalue>1.71773e-16</Hsp_evalue>
      <Hsp_query-from>94</Hsp_query-from>
      <Hsp_query-to>489</Hsp_query-to>
      <Hsp_hit-from>675</Hsp_hit-from>
      <Hsp_hit-to>806</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>RQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLA---TLKRASFAKSVIGTPEFMAPEMYEE-HYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFNKVAFPEVKEIIEGCI</Hsp_qseq>
      <Hsp_hseq>RETCQGLKFLH--DKHIIHRDIKSDNVLLD-TRARVKITDFGFCARLTDKRSKRA-TMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATNGTPKLKHPESLSLEIKRFLSVCL</Hsp_hseq>
      <Hsp_midline>R+  +GL FLH  D  IIHRD+K DN+ +      VK+ D G     T KR+  A +++GTP +MAPE+ ++  YDE +DV++ G+  +EM   E PY        +Y   T+G       +    E+K  +  C+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>7.71436e-16</Hsp_evalue>
      <Hsp_query-from>46</Hsp_query-from>
      <Hsp_query-to>510</Hsp_query-to>
      <Hsp_hit-from>315</Hsp_hit-from>
      <Hsp_hit-to>476</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>166</Hsp_align-len>
      <Hsp_qseq>LKRFKQMKIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKRASFAKSVIGTPEFMAPEMYE-EHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQI--------YRRVTSGVK--PASFNKVAFPEVKEIIEGCIRQSKHDR</Hsp_qseq>
      <Hsp_hseq>LERGGRISEKVLGKIAEAVLRGLSYLHEKK--VIHRDIKPQNILLN-ENGQVKLCDFGVSGEAVNSLATTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANGKFPCSSEKMAANIAPFELLMWILTFTPELKDEPES-NIIWSPSFKSFIDYCLKKDSRER</Hsp_hseq>
      <Hsp_midline>L+R  ++  KV+      +L+GL +LH +   +IHRD+K  NI +    G VK+ D G++     S A +  GT  +MAPE  + + Y  + DV++ G+ +LE+A  ++P S  + AA I            T  +K  P S N +  P  K  I+ C+++   +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.4034</Hsp_bit-score>
      <Hsp_score>176</Hsp_score>
      <Hsp_evalue>7.80447e-16</Hsp_evalue>
      <Hsp_query-from>91</Hsp_query-from>
      <Hsp_query-to>510</Hsp_query-to>
      <Hsp_hit-from>720</Hsp_hit-from>
      <Hsp_hit-to>859</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>147</Hsp_align-len>
      <Hsp_qseq>CRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLAT------LKRASFAKSVIGTPEFMAPEMY-EEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFNKVAFPEVKEIIEGCIRQSKHDR</Hsp_qseq>
      <Hsp_hseq>CRETLSGLEFLHSKG--VLHRDIKSDNILLS-MEGDIKLTDFGFCAQINELNLKRTT----MVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPPYLNETPLRALYLIATNGTPKLKEPENLSSSLKKFLDWCLCVEPEDR</Hsp_hseq>
      <Hsp_midline>CR+ L GL FLH++   ++HRD+K DNI ++   G +K+ D G         LKR +    ++GTP +MAPE+   + Y   VD+++ G+ ++EM   E PY        +Y   T+G       +     +K+ ++ C+     DR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>3.89466e-15</Hsp_evalue>
      <Hsp_query-from>58</Hsp_query-from>
      <Hsp_query-to>378</Hsp_query-to>
      <Hsp_hit-from>919</Hsp_hit-from>
      <Hsp_hit-to>1025</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>110</Hsp_align-len>
      <Hsp_qseq>KQMKIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLA--TLKRASFAKSVIGTPEFMAPE-MYEEHYDESVDVYAFGMCMLEMATSEYPYS</Hsp_qseq>
      <Hsp_hseq>QRLSVRRAKFYAAEVLLALKYFH--DNGVIYRDLKLENILLT-PEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFS</Hsp_hseq>
      <Hsp_midline>+++ ++  + +  ++L  L + H  D  +I+RDLK +NI +T P G +K+ D GL    +   +   +  GTPEFMAPE + E+ Y ++VD +AFG+ + +M   + P+S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>5.31771e-15</Hsp_evalue>
      <Hsp_query-from>46</Hsp_query-from>
      <Hsp_query-to>402</Hsp_query-to>
      <Hsp_hit-from>308</Hsp_hit-from>
      <Hsp_hit-to>427</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>123</Hsp_align-len>
      <Hsp_qseq>LKRFKQMKIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKRASFAKSVIGTPEFMAPEMYE-EHYDESVDVYAFGMCMLEMATSEYPYSE---CQNAAQI</Hsp_qseq>
      <Hsp_hseq>LKRGGRISERVIGKIAESVLRGLSYLHERK--VIHRDIKPQNILLN-EKGEIKLCDFGVSGEAVNSLAMTFTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRFPFESDKITQNVAPI</Hsp_hseq>
      <Hsp_midline>LKR  ++  +V+      +L+GL +LH R   +IHRD+K  NI +    G +K+ D G++     S A +  GT  +MAPE  + + Y  + DV++ G+ +LE+A   +P+      QN A I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>1.14423e-14</Hsp_evalue>
      <Hsp_query-from>94</Hsp_query-from>
      <Hsp_query-to>510</Hsp_query-to>
      <Hsp_hit-from>126</Hsp_hit-from>
      <Hsp_hit-to>264</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>147</Hsp_align-len>
      <Hsp_qseq>RQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLA------TLKRASFAKSVIGTPEFMAPEMYEE--HYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFNKVAFPEVKEIIEGCIRQSKHDR</Hsp_qseq>
      <Hsp_hseq>RELLVALKCIHKDN--VIHRDIKAANVLITN-EGNVKLCDFGVAAQVNQTSLRRQTMA----GTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYCDVE-ALRAMQLIIKSKPPRLEDRSYSTSLKEFIALCLDEDPKER</Hsp_hseq>
      <Hsp_midline>R++L  L  +H  +  +IHRD+K  N+ IT   G+VK+ D G+A      +L+R + A    GTP +MAPE+  E  +YD  VD+++ G+   E+AT   PY + + A +  + +     P   ++     +KE I  C+ +   +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>1.82474e-13</Hsp_evalue>
      <Hsp_query-from>94</Hsp_query-from>
      <Hsp_query-to>510</Hsp_query-to>
      <Hsp_hit-from>817</Hsp_hit-from>
      <Hsp_hit-to>969</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>159</Hsp_align-len>
      <Hsp_qseq>RQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKRASFA----------------KSVIGTPEFMAPEMYEE--HYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTS-GVK-PASFNKVAFPEVKEIIEGCIRQSKHDR</Hsp_qseq>
      <Hsp_hseq>RQILEALSYIHSQ--GIIHRDLKPMNIFI-DESRNVKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVLDGTGHYNEKIDMYSLGIIFFEMI---YPFSTGMERVNILKKLRSVSIEFPPDFDDNKMKVEKKIIRLLIDHDPNKR</Hsp_hseq>
      <Hsp_midline>RQIL+ L ++H++   IIHRDLK  NIFI   + +VK+GD GLA     S                   S IGT  ++A E+ +   HY+E +D+Y+ G+   EM    YP+S       I +++ S  ++ P  F+       K+II   I    + R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>3.03552e-13</Hsp_evalue>
      <Hsp_query-from>52</Hsp_query-from>
      <Hsp_query-to>432</Hsp_query-to>
      <Hsp_hit-from>1274</Hsp_hit-from>
      <Hsp_hit-to>1399</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>132</Hsp_align-len>
      <Hsp_qseq>RFKQMKIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKRASFAKSVI---GTPEFMAPEMYE--EHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKP</Hsp_qseq>
      <Hsp_hseq>RFDEPLIKHLTT---QVLKGLAYLHSKG--ILHRDMKADNLLLD-QDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAP</Hsp_hseq>
      <Hsp_midline>RF +  IK + +   Q+LKGL +LH++   I+HRD+K DN+ +    G  K+ D G++   +  ++ S +   GT  +MAPEM +  + Y   VD+++ G  +LEM   + P+S  +  A +++   S   P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>4.20142e-13</Hsp_evalue>
      <Hsp_query-from>97</Hsp_query-from>
      <Hsp_query-to>420</Hsp_query-to>
      <Hsp_hit-from>210</Hsp_hit-from>
      <Hsp_hit-to>315</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>110</Hsp_align-len>
      <Hsp_qseq>QILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLK-RASFAKSVIGTPEFMAPEMYE-EHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTS</Hsp_qseq>
      <Hsp_hseq>QIANALDYMHKKN--IIHRDIKPENILI-GFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPPFEE-EMKDTTYKRIAA</Hsp_hseq>
      <Hsp_midline>QI   L ++H ++  IIHRD+K +NI I G    +K+ D G + +    +  K+V GT ++++PEM E   YD ++D +A G+   E+ T   P+ E +     Y+R+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>4.28157e-13</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>510</Hsp_query-to>
      <Hsp_hit-from>175</Hsp_hit-from>
      <Hsp_hit-to>325</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>158</Hsp_align-len>
      <Hsp_qseq>SYLKRFKQMKIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKRASFAKSVIGTPEFMAPEMYE-EHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFNKVAFPEVKEIIEGCIRQSKHDR</Hsp_qseq>
      <Hsp_hseq>SLLRKSQRFPNPVAKFYAAEVCLALEYLHSKD--IIYRDLKPENILLDK-NGHIKITDFGFAKYV-PDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNS-NTMKTYENILNA--ELKFPPFFHPDAQDLLKKLITRDLSER</Hsp_hseq>
      <Hsp_midline>S L++ ++    V + +  ++   L +LH++D  II+RDLK +NI +    G +K+ D G A         ++ GTP+++APE+   + Y++SVD ++FG+ + EM     P+    N  + Y  + +      F     P+ +++++  I +   +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>5.33497e-13</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>510</Hsp_query-to>
      <Hsp_hit-from>174</Hsp_hit-from>
      <Hsp_hit-to>324</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>SYLKRFKQMKIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKRASFAKSVIGTPEFMAPEMYEEH-YDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVK--PASFNKVAFPEVKEIIEGCIRQSKHDR</Hsp_qseq>
      <Hsp_hseq>SLLRKSQRFPNPVAKFYAAEVCLALEYLHSKD--IIYRDLKPENILLD-KNGHIKITDFGFAKYV-PDVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDS-NTMKTYEKILNAELRFPPFFNE----DVKDLLSRLITRDLSQR</Hsp_hseq>
      <Hsp_midline>S L++ ++    V + +  ++   L +LH++D  II+RDLK +NI +    G +K+ D G A         ++ GTP+++APE+     Y++S+D ++FG+ + EM     P+ +  N  + Y ++ +     P  FN+    +VK+++   I +    R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>1.03856e-12</Hsp_evalue>
      <Hsp_query-from>67</Hsp_query-from>
      <Hsp_query-to>378</Hsp_query-to>
      <Hsp_hit-from>180</Hsp_hit-from>
      <Hsp_hit-to>290</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>114</Hsp_align-len>
      <Hsp_qseq>KIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKRASFAKSVIGTPEFMAPEMYEEHYD----------ESVDVYAFGMCMLEMATSEYPYS</Hsp_qseq>
      <Hsp_hseq>KTKSITHIITQIMDAIEYVHNKG--IYHRDIKPENILISGIDWTIKLTDWGLATTDKTSMDRNV-GSERYMSPELFDSNLDIKERKEPYDCAKVDLWAMGIVFLNIVFHKNPFS</Hsp_hseq>
      <Hsp_midline>K K +     QI+  + ++H +   I HRD+K +NI I+G   ++K+ D GLAT  + S  ++V G+  +M+PE+++ + D            VD++A G+  L +   + P+S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>1.44403e-12</Hsp_evalue>
      <Hsp_query-from>142</Hsp_query-from>
      <Hsp_query-to>375</Hsp_query-to>
      <Hsp_hit-from>481</Hsp_hit-from>
      <Hsp_hit-to>564</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>IIHRDLKCDNIFITGPTGSVKVGDLGLATLKRASFAKSVIGTPEFMAPEMYEE------HYDESVDVYAFGMCMLEMATSEYPY</Hsp_qseq>
      <Hsp_hseq>IIHRDVKPTNILCSANQGTVKLCDFGVSGNLVASLAKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPY</Hsp_hseq>
      <Hsp_midline>IIHRD+K  NI  +   G+VK+ D G++    AS AK+ IG   +MAPE  +        Y    D+++ G+ +LEMA   YPY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>1.71368e-12</Hsp_evalue>
      <Hsp_query-from>82</Hsp_query-from>
      <Hsp_query-to>510</Hsp_query-to>
      <Hsp_hit-from>124</Hsp_hit-from>
      <Hsp_hit-to>260</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>146</Hsp_align-len>
      <Hsp_qseq>RSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKRASFAKSVIGTPEFMAPEMYEEHYDESV-DVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGV--KPASFNKVAFPEVKEIIEGCIRQSKHDR</Hsp_qseq>
      <Hsp_hseq>KTYVTQTLLGLKYLHGEG--VIHRDIKAANILLSA-DNTVKLADFGVSTIVNSS-ALTLAGTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNPPYHNLTD-ANIYYAVENDTYYPPSSFSE----PLKDFLSKCFVKNMYKR</Hsp_hseq>
      <Hsp_midline>+++  Q L GL +LH     +IHRD+K  NI ++    +VK+ D G++T+  +S A ++ GT  +MAPE+       ++ D+++ G  ++EM T   PY    + A IY  V +     P+SF++     +K+ +  C  ++ + R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>4.94002e-12</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>489</Hsp_query-to>
      <Hsp_hit-from>157</Hsp_hit-from>
      <Hsp_hit-to>300</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>153</Hsp_align-len>
      <Hsp_qseq>SYLKRFKQMKIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKRASFAKSVIGTPEFMAPE-MYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSG--VKPASFNKVAFPEVKEIIEGCI</Hsp_qseq>
      <Hsp_hseq>SLLRKSQRFPNPVAKFYAAEVILALEYLHAHN--IIYRDLKPENILLDR-NGHIKITDFGFAK-EVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDT-TPMKTYEKILQGKVVYPPYFH----PDVVDLLSKLI</Hsp_hseq>
      <Hsp_midline>S L++ ++    V + +  +++  L +LH  +  II+RDLK +NI +    G +K+ D G A  +  +   ++ GTP+++APE +  + Y++SVD ++ G+ + EM     P+ +     + Y ++  G  V P  F+    P+V +++   I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>5.48893e-12</Hsp_evalue>
      <Hsp_query-from>52</Hsp_query-from>
      <Hsp_query-to>504</Hsp_query-to>
      <Hsp_hit-from>509</Hsp_hit-from>
      <Hsp_hit-to>654</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>RFKQMKIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKRASFAKSVIGTPEFMAPEMY--EEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFNKVAFP------EVKEIIEGCI-RQSKH</Hsp_qseq>
      <Hsp_hseq>RFSEDRAKF---YIAELVLALEHLHDND--IVYRDLKPENILLDA-NGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFF-AENNQKMYQKI-------AFGKVKFPRDVLSQEGRSFVKGLLNRNPKH</Hsp_hseq>
      <Hsp_midline>RF + + K    +  +++  L  LH  D  I++RDLK +NI +    G++ + D GL+         +  GT E++APE+   E  Y + VD ++ G+ + EM     P+   +N  ++Y+++       +F KV FP      E +  ++G + R  KH</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>7.54013e-12</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>510</Hsp_query-to>
      <Hsp_hit-from>108</Hsp_hit-from>
      <Hsp_hit-to>260</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>168</Hsp_align-len>
      <Hsp_qseq>SYLKRFKQMKIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLA-----TLKRASFAKSVIGTPEFMAPEMY---EEHYDESVDVYAFGMCMLEMATSEYP---YSECQNAAQIYRRVTSGVKPASFNKVAFPEVKEIIEGCIRQSKHDR</Hsp_qseq>
      <Hsp_hseq>SYVNGLPEEKVSFI---IHEVTLGLKYLHEQRK--IHRDIKAANILL-NEEGMVKLGDFGVSGHIRSTLKRDTF----VGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPPLSKYDPMKVMTNLPKR-----KPPKLQGPFSDAAKDFVAGCLVKTPADR</Hsp_hseq>
      <Hsp_midline>SY+    + K+  +     ++  GL +LH +    IHRD+K  NI +    G VK+GD G++     TLKR +F    +GTP +MAPE+     + Y+E  D+++ G+   E+     P   Y   +    + +R     KP           K+ + GC+ ++  DR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>8.47475e-12</Hsp_evalue>
      <Hsp_query-from>46</Hsp_query-from>
      <Hsp_query-to>414</Hsp_query-to>
      <Hsp_hit-from>170</Hsp_hit-from>
      <Hsp_hit-to>293</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>128</Hsp_align-len>
      <Hsp_qseq>LKRFKQMKIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATL--KRASFAKSVIGTPEFMAPE-MYEEHYDES--VDVYAFGMCMLEMATSEYPYSECQNAAQIYRRV</Hsp_qseq>
      <Hsp_hseq>LKRRKVLTEPEVRFFTTQICGAIKYMHSRR--VIHRDLKLGNIFFDS-NYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPF-QARDVNTIYERI</Hsp_hseq>
      <Hsp_midline>LKR K +    +R +  QI   + ++H+R   +IHRDLK  NIF      ++K+GD GLA +    +    ++ GTP ++APE +  +H   S  VD+++ G+ +  +   + P+ + ++   IY R+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>1.37005e-11</Hsp_evalue>
      <Hsp_query-from>82</Hsp_query-from>
      <Hsp_query-to>510</Hsp_query-to>
      <Hsp_hit-from>445</Hsp_hit-from>
      <Hsp_hit-to>584</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>146</Hsp_align-len>
      <Hsp_qseq>RSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATL--KRASFAKSVIGTPEFMAPE-MYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFNKVAFPEVKEIIEGCIRQSKHDR</Hsp_qseq>
      <Hsp_hseq>RFYIAELLCALDSLHKLD--VIYRDLKPENILLDY-QGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYD-ENVPVMYKKILQ--QPLLFPDGFDPAAKDLLIGLLSRDPSRR</Hsp_hseq>
      <Hsp_midline>R +  ++L  L  LH  D  +I+RDLK +NI +    G + + D GL  L  K      +  GTPE++APE +  + Y ++VD +  G+ + EM T   PY + +N   +Y+++    +P  F     P  K+++ G + +    R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>2.06228e-11</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>375</Hsp_query-to>
      <Hsp_hit-from>267</Hsp_hit-from>
      <Hsp_hit-to>389</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>126</Hsp_align-len>
      <Hsp_qseq>SYLKRFKQMKIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATL-------------KRASFAKSVIGTPEFMAPEMYEEHY-DESVDVYAFGMCMLEMATSEYPY</Hsp_qseq>
      <Hsp_hseq>SLMKKYGSLDETCARYYAAQIIDAIDYLHSNG--IIHRDIKPENILLDGEM-KIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPF</Hsp_hseq>
      <Hsp_midline>S +K++  +     R +  QI+  + +LH+    IIHRD+K +NI + G    +K+ D G A L               ++ +KS +GT E+++PE+  + + D   D++AFG  + +M   + P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>2.06452e-11</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>372</Hsp_query-to>
      <Hsp_hit-from>284</Hsp_hit-from>
      <Hsp_hit-to>403</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>122</Hsp_align-len>
      <Hsp_qseq>SYLKRFKQM-KIKVMRSWCRQ---------ILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKRASFAKSVIGTPEFMAPEMYEEH-YDESVDVYAFGMCMLEMATSEYP</Hsp_qseq>
      <Hsp_hseq>SVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLY-RQYKIIHRDIKPSNVLINS-KGQIKLCDFGVSKKLINSIADTFVGTSTYMSPERIQGNVYSIKGDVWSLGLMIIELVTGEFP</Hsp_hseq>
      <Hsp_midline>S  KRF Q   +   ++W  +         +L GL  L+ R   IIHRD+K  N+ I    G +K+ D G++     S A + +GT  +M+PE  + + Y    DV++ G+ ++E+ T E+P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>7.44459e-11</Hsp_evalue>
      <Hsp_query-from>82</Hsp_query-from>
      <Hsp_query-to>423</Hsp_query-to>
      <Hsp_hit-from>297</Hsp_hit-from>
      <Hsp_hit-to>423</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>130</Hsp_align-len>
      <Hsp_qseq>RSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGS-VKVGDLGLATLK-RASFAKSVIGTPEFMAPEM------------YEE--HYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSG</Hsp_qseq>
      <Hsp_hseq>REISRQILTAIKYIHSMG--ISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFS-GSTQDQLYKQIGRG</Hsp_hseq>
      <Hsp_midline>R   RQIL  + ++H+    I HRDLK DNI I       VK+ D GLA ++   SF K+  GT  ++APE+            YEE   Y   VD+++ G  +  + T   P+S      Q+Y+++  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>1.14167e-10</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>408</Hsp_query-to>
      <Hsp_hit-from>543</Hsp_hit-from>
      <Hsp_hit-to>668</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>133</Hsp_align-len>
      <Hsp_qseq>SYLKRFKQMKIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATL---------KRASFAKSVIGTPEFMAPEMYEEHYDES-VDVYAFGMCMLEMATSEYPYSECQNAAQIYR</Hsp_qseq>
      <Hsp_hseq>SMLNNYGPFEESLITNFTRQILIGVAYLHKKN--IIHRDIKGANILI-DIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVF----WMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFK</Hsp_hseq>
      <Hsp_midline>S L  +   +  ++ ++ RQIL G+ +LH ++  IIHRD+K  NI I    G VK+ D G++           KRAS   SV     +M+PE+ ++    +  D+++ G  ++EM T ++P+ +      I++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>1.69342e-10</Hsp_evalue>
      <Hsp_query-from>43</Hsp_query-from>
      <Hsp_query-to>423</Hsp_query-to>
      <Hsp_hit-from>213</Hsp_hit-from>
      <Hsp_hit-to>338</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>132</Hsp_align-len>
      <Hsp_qseq>YLKRFKQMKIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKRASFAKSV---IGTPEFMAPEMY--EEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSG</Hsp_qseq>
      <Hsp_hseq>YIIQHGSLKEHHARKFARGIASALQYLHANN--IVHRDLKIENIMISS-SGEIKIIDFGLSNI--FDYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDD-ENSSILHEKIKKG</Hsp_hseq>
      <Hsp_midline>Y+ +   +K    R + R I   L +LH  +  I+HRDLK +NI I+  +G +K+ D GL+ +    + K +    G+  F APE+   + +    VD+++FG+ +  +   + P+ + +N++ ++ ++  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>1.94967e-10</Hsp_evalue>
      <Hsp_query-from>46</Hsp_query-from>
      <Hsp_query-to>510</Hsp_query-to>
      <Hsp_hit-from>215</Hsp_hit-from>
      <Hsp_hit-to>379</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>LKRFKQMKIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATL---------------KRASFAKSVIGTPEFMAPEMYEEHY-DESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFNKVAFPE-VKEIIEGCIRQSKHDR</Hsp_qseq>
      <Hsp_hseq>IKKYGSLNETCARYYASQIIDAVDSLH--NIGIIHRDIKPENILL-DKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPFK----AANEYLTFQKVMKIQYAFTAGFPQIVKDLVKKLLVRDPNDR</Hsp_hseq>
      <Hsp_midline>+K++  +     R +  QI+  +  LH  +  IIHRD+K +NI +      VK+ D G A +                  + +KS +GT E+++PE+  ++Y D   D++AFG  + +M   + P+     AA  Y      +K        FP+ VK++++  + +  +DR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>1.9991e-10</Hsp_evalue>
      <Hsp_query-from>76</Hsp_query-from>
      <Hsp_query-to>498</Hsp_query-to>
      <Hsp_hit-from>1134</Hsp_hit-from>
      <Hsp_hit-to>1294</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>164</Hsp_align-len>
      <Hsp_qseq>VMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKRASFAKSV------------------IGTPEFMAPEMYEEHYDE----SVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFNKVAFPEV-KEIIEGCIRQS</Hsp_qseq>
      <Hsp_hseq>VTQVYTFELLEGLAYLH--QSGVVHRDIKPENILLDF-NGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPWSNLDNEWAIMYHVAAGRIPQLPNRDEMTAAGRAFLERCLVQD</Hsp_hseq>
      <Hsp_midline>V + +  ++L+GL +LH     ++HRD+K +NI +    G +K  D G A     S  ++V                  +GTP +MAPE       +    + DV+A G  +LEMAT   P+S   N   I   V +G  P   N+       +  +E C+ Q </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>2.04297e-10</Hsp_evalue>
      <Hsp_query-from>97</Hsp_query-from>
      <Hsp_query-to>375</Hsp_query-to>
      <Hsp_hit-from>273</Hsp_hit-from>
      <Hsp_hit-to>385</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>115</Hsp_align-len>
      <Hsp_qseq>QILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKV--GDLGLATLKRASFAK--SVIGTPEFMAPE------------------MYEEHYDESVDVYAFGMCMLEMATSEYPY</Hsp_qseq>
      <Hsp_hseq>QILQALNYLHDQD--IVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGISPF</Hsp_hseq>
      <Hsp_midline>QIL+ L++LH +D  I+HRDLK DNI +  P    ++   D G+A    ++  +  +V+GTPE+ APE                  + +  YD   D+++ G+    M T   P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>2.80959e-10</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>477</Hsp_query-to>
      <Hsp_hit-from>151</Hsp_hit-from>
      <Hsp_hit-to>302</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>155</Hsp_align-len>
      <Hsp_qseq>SWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGS--------------------VKVGDLGLAT-LKRASFAKSVIGTPEFMAPEMYE-EHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFNKVAF--PEVKEII</Hsp_qseq>
      <Hsp_hseq>SYLQQLASALKFLRSKN--LVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVVFEMCCGTPPF-RASNHLELFKKIKRANDVITFPSYCNIEPELKELI</Hsp_hseq>
      <Hsp_midline>S+ +Q+   L FL +++  ++HRD+K  N+ ++ P                       +K+ D G A  L   S A+++ G+P +MAPE+   + Y+   D+++ G  + EM     P+    N  ++++++       +F       PE+KE+I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>6.33525e-10</Hsp_evalue>
      <Hsp_query-from>94</Hsp_query-from>
      <Hsp_query-to>423</Hsp_query-to>
      <Hsp_hit-from>221</Hsp_hit-from>
      <Hsp_hit-to>330</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>113</Hsp_align-len>
      <Hsp_qseq>RQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKRAS-FAKSVIGTPEFMAPE--MYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSG</Hsp_qseq>
      <Hsp_hseq>KQIVEGVSYCHSFN--ICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFND-DNIKKLLLKVQSG</Hsp_hseq>
      <Hsp_midline>+QI++G+ + H+ +  I HRDLK +N+ +      +K+ D G+A L+  +   K+  G+P + +PE  M   ++    DV++ G+ +  + T   P+++  N  ++  +V SG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>8.20023e-10</Hsp_evalue>
      <Hsp_query-from>73</Hsp_query-from>
      <Hsp_query-to>354</Hsp_query-to>
      <Hsp_hit-from>261</Hsp_hit-from>
      <Hsp_hit-to>358</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>101</Hsp_align-len>
      <Hsp_qseq>KVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLA-----TLKRASFAKSVIGTPEFMAPEMY--EEHYDESVDVYAFGMCMLEM</Hsp_qseq>
      <Hsp_hseq>RMVRSIMWQLLDGVSYLHQN--WVLHRDLKPANIMVT-IDGCVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAEL</Hsp_hseq>
      <Hsp_midline>+++RS   Q+L G+ +LH     ++HRDLK  NI +T   G VK+GDLGLA      L+       V+ T  + APE+     HY  +VD+++ G    E+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>9.47908e-10</Hsp_evalue>
      <Hsp_query-from>43</Hsp_query-from>
      <Hsp_query-to>510</Hsp_query-to>
      <Hsp_hit-from>435</Hsp_hit-from>
      <Hsp_hit-to>587</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>161</Hsp_align-len>
      <Hsp_qseq>YLKRFKQMKIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATL--KRASFAKSVIGTPEFMAPE-MYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSG--VKPASFNKVAFPEVKEIIEGCIRQSKHDR</Hsp_qseq>
      <Hsp_hseq>HLQKEGRFDLSRARFYTAELLCALDNLHKLD--VVYRDLKPENILLDY-QGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYD-EDVPKMYKKILQEPLVFPDGFDR----DAKDLLIGLLSRDPTRR</Hsp_hseq>
      <Hsp_midline>+L++  +  +   R +  ++L  L  LH  D  +++RDLK +NI +    G + + D GL  L  K      +  GTPE++APE +    Y ++VD +  G+ + EM T   PY + ++  ++Y+++     V P  F++    + K+++ G + +    R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>1.51722e-09</Hsp_evalue>
      <Hsp_query-from>82</Hsp_query-from>
      <Hsp_query-to>462</Hsp_query-to>
      <Hsp_hit-from>247</Hsp_hit-from>
      <Hsp_hit-to>365</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>131</Hsp_align-len>
      <Hsp_qseq>RSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATL--KRASFAKSVIGTPEFMAPEMYEEH--YDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFNKVAFPE</Hsp_qseq>
      <Hsp_hseq>RKFARGIASALIYLHANN--IVHRDLKIENIMISD-SSEIKIIDFGLSNIYDSRKQL-HTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDD-ENSSVLHEKIKQG-------KVEYPQ</Hsp_hseq>
      <Hsp_midline>R + R I   L +LH  +  I+HRDLK +NI I+  +  +K+ D GL+ +   R     +  G+  F APE+ + +      VDV++FG+ +  +   + P+ + +N++ ++ ++  G       KV +P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>2.17935e-09</Hsp_evalue>
      <Hsp_query-from>79</Hsp_query-from>
      <Hsp_query-to>390</Hsp_query-to>
      <Hsp_hit-from>106</Hsp_hit-from>
      <Hsp_hit-to>209</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>108</Hsp_align-len>
      <Hsp_qseq>MRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKRA--SFAKSVIGTPEFMAPEMY--EEHYDESVDVYAFGMCMLEMATSEYPYSECQN</Hsp_qseq>
      <Hsp_hseq>IKAWMLMTLRGVYHCHRNF--ILHRDLKPNNLLFS-PDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELML-RIPYLPGQN</Hsp_hseq>
      <Hsp_midline>+++W    L+G++  H     I+HRDLK +N+  + P G +KV D GLA    A      S + T  + APE+    +HY  ++D+++ G+   E+     PY   QN</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>2.64705e-09</Hsp_evalue>
      <Hsp_query-from>94</Hsp_query-from>
      <Hsp_query-to>345</Hsp_query-to>
      <Hsp_hit-from>310</Hsp_hit-from>
      <Hsp_hit-to>411</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>104</Hsp_align-len>
      <Hsp_qseq>RQILKGLHFLHTRDPPIIHRDLKCDNIFIT------------GPTG------SVKVGDLGLATLK-RASFAKSVIGTPEFMAPE-MYEEHYDESVDVYAFGMCM</Hsp_qseq>
      <Hsp_hseq>KQLLTGLKYLHEQN--IIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVIL</Hsp_hseq>
      <Hsp_midline>+Q+L GL +LH ++  IIHRD+K +NI +             GP         VK+ D GLA       F  ++ GTP ++APE + ++ Y   VD+++ G+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>3.86319e-09</Hsp_evalue>
      <Hsp_query-from>43</Hsp_query-from>
      <Hsp_query-to>426</Hsp_query-to>
      <Hsp_hit-from>142</Hsp_hit-from>
      <Hsp_hit-to>268</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>131</Hsp_align-len>
      <Hsp_qseq>YLKRFKQMKIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLAT-LKRASFAKSVIGTPEFMAPEMY--EEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGV</Hsp_qseq>
      <Hsp_hseq>YIVQRDKMSEQEARRFFQQIISAVEYCHRH--KIVHRDLKPENLLLDEHL-NVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDD-ESIPVLFKNISNGV</Hsp_hseq>
      <Hsp_midline>Y+ +  +M  +  R + +QI+  + + H     I+HRDLK +N+ +     +VK+ D GL+  +   +F K+  G+P + APE+   + +    VDV++ G+ +  M     P+ + ++   +++ +++GV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>4.0596e-09</Hsp_evalue>
      <Hsp_query-from>58</Hsp_query-from>
      <Hsp_query-to>402</Hsp_query-to>
      <Hsp_hit-from>103</Hsp_hit-from>
      <Hsp_hit-to>218</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>120</Hsp_align-len>
      <Hsp_qseq>KQMKIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLAT---LKRASFAKSVIGTPEFMAPE--MYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQI</Hsp_qseq>
      <Hsp_hseq>RGLELNLVKYFQWQLLQGLAFCHENK--ILHRDLKPQNLLINK-RGQLKLGDFGLARAFGIPVNTFSSEVV-TLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQL</Hsp_hseq>
      <Hsp_midline>+ +++ +++ +  Q+L+GL F H     I+HRDLK  N+ I    G +K+GD GLA    +   +F+  V+ T  + AP+  M    Y  S+D+++ G  + EM T +  +    +  Q+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>5.9065e-09</Hsp_evalue>
      <Hsp_query-from>97</Hsp_query-from>
      <Hsp_query-to>354</Hsp_query-to>
      <Hsp_hit-from>149</Hsp_hit-from>
      <Hsp_hit-to>243</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>98</Hsp_align-len>
      <Hsp_qseq>QILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKRASFAK----------SVIGTPEFMAPEMY--EEHYDESVDVYAFGMCMLEM</Hsp_qseq>
      <Hsp_hseq>QILCGLKYIHSAD--VIHRDLKPGNILCT-LNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEF</Hsp_hseq>
      <Hsp_midline>QIL GL ++H+ D  +IHRDLK  NI  T   G +K+ D GLA    A F K          + + T  + APE+    + Y +SVD++A G  + E </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>7.61621e-09</Hsp_evalue>
      <Hsp_query-from>82</Hsp_query-from>
      <Hsp_query-to>486</Hsp_query-to>
      <Hsp_hit-from>167</Hsp_hit-from>
      <Hsp_hit-to>305</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>151</Hsp_align-len>
      <Hsp_qseq>RSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKRASFAKSV------------IGTPEFMAPEM--YEEHY--DESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFNKVAFPEVKEIIEGC</Hsp_qseq>
      <Hsp_hseq>RKVVLDVVSGLEYLHSQG--ITHRDIKPSNLLISS-NGTVKISDFGVA-MSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPFN-ANSGLELFDSIIN--KP-----LEFPSYEEMLNGA</Hsp_hseq>
      <Hsp_midline>R     ++ GL +LH++   I HRD+K  N+ I+   G+VK+ D G+A +  A+ + ++            +GTP F APE+   E+ Y    ++D+++ G+ +  +   + P++   +  +++  + +  KP     + FP  +E++ G </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>1.68537e-08</Hsp_evalue>
      <Hsp_query-from>67</Hsp_query-from>
      <Hsp_query-to>429</Hsp_query-to>
      <Hsp_hit-from>420</Hsp_hit-from>
      <Hsp_hit-to>547</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>131</Hsp_align-len>
      <Hsp_qseq>KIKVMRSWC--RQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLG------LATLKRASFAKSVIGTPEFMAPEMY--EEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVK</Hsp_qseq>
      <Hsp_hseq>KLEYMEADCFFKQLIRGVVYMHEMG--VCHRDLKPENLLLTH-DGVLKITDFGNSECFKMAWEKNIHLSGGVCGSSPYIAPEEYIKEEFDPRPVDIWACGVIYMAMRTGRQLWSSAEKDDPFYMNYLKGRK</Hsp_hseq>
      <Hsp_midline>K++ M + C  +Q+++G+ ++H     + HRDLK +N+ +T   G +K+ D G      +A  K    +  V G+  ++APE Y  EE     VD++A G+  + M T    +S  +     Y     G K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>1.99976e-08</Hsp_evalue>
      <Hsp_query-from>67</Hsp_query-from>
      <Hsp_query-to>354</Hsp_query-to>
      <Hsp_hit-from>275</Hsp_hit-from>
      <Hsp_hit-to>374</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>104</Hsp_align-len>
      <Hsp_qseq>KIKVMRSWCR----QILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATL--KRASFAKSVIGTPEFMAPEMY--EEHYDESVDVYAFGMCMLEM</Hsp_qseq>
      <Hsp_hseq>EVQISHSQCKHLFKQLLLGMEYLH--DNKILHRDVKGSNILIDN-QGNLKITDFGLARKMNSRADYTNRVI-TLWYRPPELLLGTTNYGTEVDMWGCGCLLVEL</Hsp_hseq>
      <Hsp_midline>++++  S C+    Q+L G+ +LH  D  I+HRD+K  NI I    G++K+ D GLA     RA +   VI T  +  PE+     +Y   VD++  G  ++E+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>2.40205e-08</Hsp_evalue>
      <Hsp_query-from>94</Hsp_query-from>
      <Hsp_query-to>381</Hsp_query-to>
      <Hsp_hit-from>134</Hsp_hit-from>
      <Hsp_hit-to>229</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>99</Hsp_align-len>
      <Hsp_qseq>RQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKR-ASFAKSVIGTPEFMAPEMYE--EHYDESVDVYAFGMCMLEMATSEYPYSE</Hsp_qseq>
      <Hsp_hseq>RQIIIGISYCHALG--IVHRDLKPENLLLDS-FYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDE</Hsp_hseq>
      <Hsp_midline>RQI+ G+ + H     I+HRDLK +N+ +     ++K+ D G+A L+  A   ++  G+P + APE+     +   + DV++ G+ +  + T   P+ E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>4.28362e-08</Hsp_evalue>
      <Hsp_query-from>58</Hsp_query-from>
      <Hsp_query-to>363</Hsp_query-to>
      <Hsp_hit-from>546</Hsp_hit-from>
      <Hsp_hit-to>649</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>108</Hsp_align-len>
      <Hsp_qseq>KQMKIKVMRSW--CRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLAT---LKRASFAKSVIGTPEFMAPEMYEE-HYDESVDVYAFGMCMLEMATS</Hsp_qseq>
      <Hsp_hseq>KKKRLEDWRIWKIIVELSLALRFIHD-SCHIVHLDLKPANVMITF-EGNLKLGDFGMATHLPLEDKSFENE--GDREYIAPEIISDCTYDYKADIFSLGLMIVEIAAN</Hsp_hseq>
      <Hsp_midline>K+ +++  R W    ++   L F+H     I+H DLK  N+ IT   G++K+GD G+AT   L+  SF     G  E++APE+  +  YD   D+++ G+ ++E+A +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YDL214C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:74446:76545:-1 gene:YDL214C transcript:YDL214C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR2 description:Serine/threonine protein kinase; inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance; PRR2 has a paralog, NPR1, that arose from the whole genome duplication [Source:SGD;Acc:S000002373]</Hit_def>
  <Hit_accession>YDL214C</Hit_accession>
  <Hit_len>699</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>5.61215e-08</Hsp_evalue>
      <Hsp_query-from>94</Hsp_query-from>
      <Hsp_query-to>375</Hsp_query-to>
      <Hsp_hit-from>466</Hsp_hit-from>
      <Hsp_hit-to>564</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>102</Hsp_align-len>
      <Hsp_qseq>RQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATL------KRASFAKSVIGTPEFMAPEM-YEEHYD-ESVDVYAFGMCMLEMATSEYPY</Hsp_qseq>
      <Hsp_hseq>KQLINGVKYLH--DIGLSHRDLKLDNCVVT-RRGILKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFYFNEYDPRALDVWSVGIIFFCMITRRFPW</Hsp_hseq>
      <Hsp_midline>+Q++ G+ +LH  D  + HRDLK DN  +T   G +K+ D G +++       +   A  ++G+  +++PE+ Y   YD  ++DV++ G+    M T  +P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>9.31492e-08</Hsp_evalue>
      <Hsp_query-from>94</Hsp_query-from>
      <Hsp_query-to>381</Hsp_query-to>
      <Hsp_hit-from>138</Hsp_hit-from>
      <Hsp_hit-to>233</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>53</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>99</Hsp_align-len>
      <Hsp_qseq>RQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLK-RASFAKSVIGTPEFMAPEMYE--EHYDESVDVYAFGMCMLEMATSEYPYSE</Hsp_qseq>
      <Hsp_hseq>RQIIIGVSYCHALG--IVHRDLKPENLLLDHKY-NIKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDE</Hsp_hseq>
      <Hsp_midline>RQI+ G+ + H     I+HRDLK +N+ +     ++K+ D G+A L+      ++  G+P + APE+     +   + DV++ G+ +  + T   P+ E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YOR267C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:822588:824867:-1 gene:YOR267C transcript:YOR267C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRK1 description:Protein kinase; implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005793]</Hit_def>
  <Hit_accession>YOR267C</Hit_accession>
  <Hit_len>759</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>9.94198e-08</Hsp_evalue>
      <Hsp_query-from>94</Hsp_query-from>
      <Hsp_query-to>408</Hsp_query-to>
      <Hsp_hit-from>322</Hsp_hit-from>
      <Hsp_hit-to>432</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>114</Hsp_align-len>
      <Hsp_qseq>RQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKRASF------AKSVIGTPEFMAPEMY--EEHYD-ESVDVYAFGMCMLEMATSEYPYSECQNAAQIYR</Hsp_qseq>
      <Hsp_hseq>KQLTEGVKYLHSMG--LAHRDLKLDNCVMTS-QGILKLIDFGSAVVFRYPFEDGVTMAHGIVGSDPYLAPEVITSTKSYDPQCVDIWSIGIIYCCMVLKRFPWKAPRDSDDNFR</Hsp_hseq>
      <Hsp_midline>+Q+ +G+ +LH+    + HRDLK DN  +T   G +K+ D G A + R  F      A  ++G+  ++APE+    + YD + VD+++ G+    M    +P+   +++   +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YIL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:183937:186369:1 gene:YIL095W transcript:YIL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRK1 description:Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton and reduces endocytic ability of cell through the phosphorylation of the Pan1p-Sla1p-End3p protein complex; PRK1 has a paralog, ARK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001357]</Hit_def>
  <Hit_accession>YIL095W</Hit_accession>
  <Hit_len>810</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>1.30808e-07</Hsp_evalue>
      <Hsp_query-from>97</Hsp_query-from>
      <Hsp_query-to>492</Hsp_query-to>
      <Hsp_hit-from>139</Hsp_hit-from>
      <Hsp_hit-to>275</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>147</Hsp_align-len>
      <Hsp_qseq>QILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLAT--------LKRASFAKSVI---GTPEFMAPEMYEEH----YDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFNKVAFPEVKEIIEGCIR</Hsp_qseq>
      <Hsp_hseq>QTVQGITAMHALQPPLIHRDIKIENVLISH-DGLYKVCDFGSVSGVIRPPRNTQEFNYVQHDILTNTTAQYRSPEMIDLYRGLPIDEKSDIWALGVFLYKICYYTTPFEKSGEA---------GILHARYQYPSFPQYSDRLKNLIR</Hsp_hseq>
      <Hsp_midline>Q ++G+  +H   PP+IHRD+K +N+ I+   G  KV D G  +         +  ++ +  I    T ++ +PEM + +     DE  D++A G+ + ++     P+ +   A         G+  A +   +FP+  + ++  IR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>1.66904e-07</Hsp_evalue>
      <Hsp_query-from>37</Hsp_query-from>
      <Hsp_query-to>354</Hsp_query-to>
      <Hsp_hit-from>127</Hsp_hit-from>
      <Hsp_hit-to>233</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>109</Hsp_align-len>
      <Hsp_qseq>HSYLKRFKQMKIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLA-TLKRASFAKSVIGTPEFMAPEMYE--EHYDESVDVYAFGMCMLEM</Hsp_qseq>
      <Hsp_hseq>NRYVTNKLEMPLKHIRLYTYQIARGMLYLHGLG--VCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSISYICSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEM</Hsp_hseq>
      <Hsp_midline>+ Y+    +M +K +R +  QI +G+ +LH     + HRD+K  N+ +   TG +K+ D G A  L+    + S I +  + APE+      Y   +D++  G  M EM</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>1.96095e-07</Hsp_evalue>
      <Hsp_query-from>46</Hsp_query-from>
      <Hsp_query-to>354</Hsp_query-to>
      <Hsp_hit-from>110</Hsp_hit-from>
      <Hsp_hit-to>210</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>105</Hsp_align-len>
      <Hsp_qseq>LKRFKQMKIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKRASFAKSVIGTPEFMAPE--MYEEHYDESVDVYAFGMCMLEM</Hsp_qseq>
      <Hsp_hseq>LLQTRPLEKQFVQYFLYQILRGLKYVHSAG--VIHRDLKPSNILI-NENCDLKICDFGLARIQDPQMT-GYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEM</Hsp_hseq>
      <Hsp_midline>L + + ++ + ++ +  QIL+GL ++H+    +IHRDLK  NI I      +K+ D GLA ++        + T  + APE  +  + YD  VD+++ G    EM</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YAR018C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:170396:171703:-1 gene:YAR018C transcript:YAR018C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN3 description:Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol [Source:SGD;Acc:S000000071]</Hit_def>
  <Hit_accession>YAR018C</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>2.21789e-07</Hsp_evalue>
      <Hsp_query-from>142</Hsp_query-from>
      <Hsp_query-to>423</Hsp_query-to>
      <Hsp_hit-from>170</Hsp_hit-from>
      <Hsp_hit-to>303</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>135</Hsp_align-len>
      <Hsp_qseq>IIHRDLKCDNIFIT------------------------------GPTGS--------VKVGDLGLATLKRAS--FAKSVIGTPEFMAPE-MYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSG</Hsp_qseq>
      <Hsp_hseq>VIHRDLKPGNIFLSYDDSDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLAKSLETSIQFATTYVGTPYYMSPEVLMDQPYSPLSDIWSLGCVIFEMCSLHPPF-QAKNYLELQTKIKNG</Hsp_hseq>
      <Hsp_midline>+IHRDLK  NIF++                              G  GS        VK+GD GLA     S  FA + +GTP +M+PE + ++ Y    D+++ G  + EM +   P+ + +N  ++  ++ +G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YNL183C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:293137:295509:-1 gene:YNL183C transcript:YNL183C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NPR1 description:Protein kinase; stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p; negatively regulates Ldb19p-mediated endocytosis through phosphorylation of Ldb19p, which prevents its association with the plasma membrane; Npr1p activity is negatively regulated via phosphorylation by the TOR complex; NPR1 has a paralog, PRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005127]</Hit_def>
  <Hit_accession>YNL183C</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.3654</Hsp_bit-score>
      <Hsp_score>111</Hsp_score>
      <Hsp_evalue>2.701e-07</Hsp_evalue>
      <Hsp_query-from>94</Hsp_query-from>
      <Hsp_query-to>375</Hsp_query-to>
      <Hsp_hit-from>543</Hsp_hit-from>
      <Hsp_hit-to>641</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>102</Hsp_align-len>
      <Hsp_qseq>RQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKRASFAKS------VIGTPEFMAPE--MYEEHYDESVDVYAFGMCMLEMATSEYPY</Hsp_qseq>
      <Hsp_hseq>KQILTGVQYLHSIG--LAHRDLKLDNCVIN-EKGIVKLIDFGAAVVFSYPFSKNLVEASGIVGSDPYLAPEVCIFAKYDPRPVDIWSSAIIFACMILKKFPW</Hsp_hseq>
      <Hsp_midline>+QIL G+ +LH+    + HRDLK DN  I    G VK+ D G A +    F+K+      ++G+  ++APE  ++ ++    VD+++  +    M   ++P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YKL168C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:131288:133462:-1 gene:YKL168C transcript:YKL168C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KKQ8 description:Putative serine/threonine protein kinase with unknown cellular role; KKQ8 has a paralog, HAL5, that arose from the whole genome duplication [Source:SGD;Acc:S000001651]</Hit_def>
  <Hit_accession>YKL168C</Hit_accession>
  <Hit_len>724</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.3654</Hsp_bit-score>
      <Hsp_score>111</Hsp_score>
      <Hsp_evalue>2.84904e-07</Hsp_evalue>
      <Hsp_query-from>94</Hsp_query-from>
      <Hsp_query-to>369</Hsp_query-to>
      <Hsp_hit-from>545</Hsp_hit-from>
      <Hsp_hit-to>642</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>101</Hsp_align-len>
      <Hsp_qseq>RQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATL------KRASFAKSVIGTPEFMAPEMY--EEHYDES-VDVYAFGMCMLEMATSEY</Hsp_qseq>
      <Hsp_hseq>KQLLHGVKFMH--DHGIAHCDLKPENILFY-PHGLLKICDFGTSSVFQTAWERRVHAQKGIIGSEPYVAPEEFVDGEYYDPRLIDCWSCGVVYITMILGHY</Hsp_hseq>
      <Hsp_midline>+Q+L G+ F+H  D  I H DLK +NI    P G +K+ D G +++      +R    K +IG+  ++APE +   E+YD   +D ++ G+  + M    Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YIL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:287790:288908:-1 gene:YIL035C transcript:YIL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA1 description:Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000001297]</Hit_def>
  <Hit_accession>YIL035C</Hit_accession>
  <Hit_len>372</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.9802</Hsp_bit-score>
      <Hsp_score>110</Hsp_score>
      <Hsp_evalue>3.05233e-07</Hsp_evalue>
      <Hsp_query-from>79</Hsp_query-from>
      <Hsp_query-to>447</Hsp_query-to>
      <Hsp_hit-from>172</Hsp_hit-from>
      <Hsp_hit-to>295</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>126</Hsp_align-len>
      <Hsp_qseq>MRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKRASFAKSV-IGTPEFMAPEMYEEH--YDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFNK</Hsp_qseq>
      <Hsp_hseq>IRFYMFELLKALDYCHSM--GIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEK</Hsp_hseq>
      <Hsp_midline>+R +  ++LK L + H+    I+HRD+K  N+ I      +++ D GLA     +   +V + +  F  PE+  ++  YD S+D+++FG  +  M     P+    +      ++   +  + F K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.3654</Hsp_bit-score>
      <Hsp_score>111</Hsp_score>
      <Hsp_evalue>3.17198e-07</Hsp_evalue>
      <Hsp_query-from>94</Hsp_query-from>
      <Hsp_query-to>375</Hsp_query-to>
      <Hsp_hit-from>1212</Hsp_hit-from>
      <Hsp_hit-to>1304</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>96</Hsp_align-len>
      <Hsp_qseq>RQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKRASFAKSVIGTPEFMAPEMY--EEHYDESVDVYAFGMCMLEMATSEYPY</Hsp_qseq>
      <Hsp_hseq>KQVVAGIKHLH--DQGIVHRDIKDENVIVDS-KGFVKIIDFGSAAYVKSGPFDVFVGTIDYAAPEVLGGNPYEGQPQDIWAIGILLYTVVFKENPF</Hsp_hseq>
      <Hsp_midline>+Q++ G+  LH  D  I+HRD+K +N+ +    G VK+ D G A   ++      +GT ++ APE+     +  +  D++A G+ +  +   E P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.9802</Hsp_bit-score>
      <Hsp_score>110</Hsp_score>
      <Hsp_evalue>3.30275e-07</Hsp_evalue>
      <Hsp_query-from>43</Hsp_query-from>
      <Hsp_query-to>378</Hsp_query-to>
      <Hsp_hit-from>242</Hsp_hit-from>
      <Hsp_hit-to>363</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>125</Hsp_align-len>
      <Hsp_qseq>YLKRFKQMKIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKRASFA------------KSVIGTPEFMAPE-MYEEHYDESVDVYAFGMCMLEMATSEYPYS</Hsp_qseq>
      <Hsp_hseq>HLKEHGTLDETTVSFYAAEISCALRFLHTKG--VVYRDLKPENCLL-NQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYT</Hsp_hseq>
      <Hsp_midline>+LK    +    +  +  +I   L FLHT+   +++RDLK +N  +    G + + D GL+       A             S+IGTPE+ APE +  + Y ++ D Y+ G  + +M   + PY+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YNL020C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:595623:597539:-1 gene:YNL020C transcript:YNL020C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ARK1 description:Serine/threonine protein kinase; involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis; ARK1 has a paralog, PRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004965]</Hit_def>
  <Hit_accession>YNL020C</Hit_accession>
  <Hit_len>638</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.9802</Hsp_bit-score>
      <Hsp_score>110</Hsp_score>
      <Hsp_evalue>3.37055e-07</Hsp_evalue>
      <Hsp_query-from>97</Hsp_query-from>
      <Hsp_query-to>492</Hsp_query-to>
      <Hsp_hit-from>140</Hsp_hit-from>
      <Hsp_hit-to>276</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>147</Hsp_align-len>
      <Hsp_qseq>QILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLA--------TLKRASFAKSVI---GTPEFMAPEMYEEH----YDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFNKVAFPEVKEIIEGCIR</Hsp_qseq>
      <Hsp_hseq>QVTQGVAAMHALQPPLIHRDIKIENVLISA-NNEYKLCDFGSVCGIIRPPRNSQELSYVQQDILKNTTAQYRSPEMIDTFRGLPIDEKSDIWALGIFLYKLCYYTTPFEKGGDLA-----ILSG----KFEFPLYPNYSEQLKGLIR</Hsp_hseq>
      <Hsp_midline>Q+ +G+  +H   PP+IHRD+K +N+ I+      K+ D G            +  S+ +  I    T ++ +PEM +       DE  D++A G+ + ++     P+ +  + A     + SG     F    +P   E ++G IR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.9802</Hsp_bit-score>
      <Hsp_score>110</Hsp_score>
      <Hsp_evalue>3.46262e-07</Hsp_evalue>
      <Hsp_query-from>58</Hsp_query-from>
      <Hsp_query-to>390</Hsp_query-to>
      <Hsp_hit-from>143</Hsp_hit-from>
      <Hsp_hit-to>257</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>119</Hsp_align-len>
      <Hsp_qseq>KQMKIKVMRSWCR---QILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLAT--LKRASFAKSVIGTPEFMAPEMY---EEHYDESVDVYAFGMCMLEMATSEYPYSECQN</Hsp_qseq>
      <Hsp_hseq>KKRRLKEMNA-CRLFSQLISGVHYIHSKG--LVHRDLKLENLLLDKNENLV-ITDFGFVNEFCSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPWDDDPN</Hsp_hseq>
      <Hsp_midline>K+ ++K M + CR   Q++ G+H++H++   ++HRDLK +N+ +      V + D G       R    K+  G+P + APE+    E +     D+++ G+ +  +     P+ +  N</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.3654</Hsp_bit-score>
      <Hsp_score>111</Hsp_score>
      <Hsp_evalue>3.53487e-07</Hsp_evalue>
      <Hsp_query-from>64</Hsp_query-from>
      <Hsp_query-to>291</Hsp_query-to>
      <Hsp_hit-from>249</Hsp_hit-from>
      <Hsp_hit-to>333</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>89</Hsp_align-len>
      <Hsp_qseq>MKIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLA-------------TLKRASFAKSVIGTPEFMAPEM</Hsp_qseq>
      <Hsp_hseq>LSFQETREILRGVVLGLEYLHYQG--IIHRDIKPANLLISG-DGTVKISDFGVSLAASSTNSSDSSESLDELELAKTV-GTPAFFAPEM</Hsp_hseq>
      <Hsp_midline>+  +  R   R ++ GL +LH +   IIHRD+K  N+ I+G  G+VK+ D G++             +L     AK+V GTP F APEM</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.595</Hsp_bit-score>
      <Hsp_score>109</Hsp_score>
      <Hsp_evalue>4.34362e-07</Hsp_evalue>
      <Hsp_query-from>37</Hsp_query-from>
      <Hsp_query-to>351</Hsp_query-to>
      <Hsp_hit-from>116</Hsp_hit-from>
      <Hsp_hit-to>225</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>113</Hsp_align-len>
      <Hsp_qseq>HSYLKRFKQMKIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLA------TLKRASFAKSVIGTPEFMAPEMYEEH--YDESVDVYAFGMCMLE</Hsp_qseq>
      <Hsp_hseq>HQIIKSGQPLTDAHYQSFTYQILCGLKYIHSAD--VLHRDLKPGNLLVNADC-QLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAE</Hsp_hseq>
      <Hsp_midline>H  +K  + +     +S+  QIL GL ++H+ D  ++HRDLK  N+ +      +K+ D GLA       ++ + F    + T  + APE+   +  Y +++DV++ G  + E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.2098</Hsp_bit-score>
      <Hsp_score>108</Hsp_score>
      <Hsp_evalue>6.07701e-07</Hsp_evalue>
      <Hsp_query-from>76</Hsp_query-from>
      <Hsp_query-to>408</Hsp_query-to>
      <Hsp_hit-from>112</Hsp_hit-from>
      <Hsp_hit-to>223</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>116</Hsp_align-len>
      <Hsp_qseq>VMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLAT---LKRASFAKSVIGTPEFMAPEMY--EEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYR</Hsp_qseq>
      <Hsp_hseq>IVKKFMMQLCKGIAYCHSHR--ILHRDLKPQNLLIN-KDGNLKLGDFGLARAFGVPLRAYTHEIV-TLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFK</Hsp_hseq>
      <Hsp_midline>+++ +  Q+ KG+ + H+    I+HRDLK  N+ I    G++K+GD GLA    +   ++   ++ T  + APE+    + Y   VD ++ G    EM   +  +S      QI++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.2098</Hsp_bit-score>
      <Hsp_score>108</Hsp_score>
      <Hsp_evalue>6.65296e-07</Hsp_evalue>
      <Hsp_query-from>37</Hsp_query-from>
      <Hsp_query-to>354</Hsp_query-to>
      <Hsp_hit-from>136</Hsp_hit-from>
      <Hsp_hit-to>242</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>109</Hsp_align-len>
      <Hsp_qseq>HSYLKRFKQMKIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLAT-LKRASFAKSVIGTPEFMAPEMY--EEHYDESVDVYAFGMCMLEM</Hsp_qseq>
      <Hsp_hseq>HEYFDNGSKMPTKHIKLYTFQILRALLTLHSMS--ICHGDLKPSNILIIPSSGIAKVCDFGSAQRLDDNTELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEM</Hsp_hseq>
      <Hsp_midline>H Y     +M  K ++ +  QIL+ L  LH+    I H DLK  NI I   +G  KV D G A  L   +  K+   +  + APE+    + Y   +D+++ G  + EM</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.2098</Hsp_bit-score>
      <Hsp_score>108</Hsp_score>
      <Hsp_evalue>6.67826e-07</Hsp_evalue>
      <Hsp_query-from>97</Hsp_query-from>
      <Hsp_query-to>510</Hsp_query-to>
      <Hsp_hit-from>140</Hsp_hit-from>
      <Hsp_hit-to>275</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>QILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLAT--LKRASFAKSVIGTPEFMAPEMYEEH-YDE-SVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFNKVAFPEVKEIIEGCIRQSKHDR</Hsp_qseq>
      <Hsp_hseq>QISGAVYYAHSMH--CVHRDLKLENILL-DKNGNAKLTDFGFTRECMTKTTL-ETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNE--EPKYDAKVIPDDARDLISRLLAKNPGER</Hsp_hseq>
      <Hsp_midline>QI   +++ H+     +HRDLK +NI +    G+ K+ D G     + + +  ++V GT  +MAPE+ E   YD   +D+++ G+ +  + T   P+ +   A   ++ V    +P    KV   + +++I   + ++  +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YDL079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:312951:314748:-1 gene:YDL079C transcript:YDL079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRK1 description:Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication [Source:SGD;Acc:S000002237]</Hit_def>
  <Hit_accession>YDL079C</Hit_accession>
  <Hit_len>501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.2098</Hsp_bit-score>
      <Hsp_score>108</Hsp_score>
      <Hsp_evalue>7.5081e-07</Hsp_evalue>
      <Hsp_query-from>46</Hsp_query-from>
      <Hsp_query-to>474</Hsp_query-to>
      <Hsp_hit-from>250</Hsp_hit-from>
      <Hsp_hit-to>407</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>LKRFKQMKIKVMRS----WCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLAT-LKRASFAKSVIGTPEFMAPEMY--EEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRV----------TSGVKPASFNKVAFPEVKEI</Hsp_qseq>
      <Hsp_hseq>LRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNV-PRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKIMGIPTKDEISGMNP-NYEDHVFPNIKPI</Hsp_hseq>
      <Hsp_midline>L+ F  +K+++ R     +  Q+ K L++LH   P I HRD+K  N+ +   T S K+ D G A  LK      S I +  + APE+     +Y   VDV++    + E+   +  +S      Q+   +           SG+ P ++    FP +K I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YJR059W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:545787:548243:1 gene:YJR059W transcript:YJR059W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK2 description:Serine/threonine protein kinase; involved in regulation of ion transport across plasma membrane; carboxyl terminus is essential for glucose-dependent Pma1p activation via phosphorylation of Pma1p-Ser899; enhances spermine uptake; PTK2 has a paralog, PTK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003820]</Hit_def>
  <Hit_accession>YJR059W</Hit_accession>
  <Hit_len>818</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.2098</Hsp_bit-score>
      <Hsp_score>108</Hsp_score>
      <Hsp_evalue>8.4328e-07</Hsp_evalue>
      <Hsp_query-from>94</Hsp_query-from>
      <Hsp_query-to>408</Hsp_query-to>
      <Hsp_hit-from>370</Hsp_hit-from>
      <Hsp_hit-to>493</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>127</Hsp_align-len>
      <Hsp_qseq>RQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLAT---------LKRASFAKSVIGTPEFMAPE-MY---EEHYDE---------SVDVYAFGMCMLEMATSEYPYSECQNAAQIYR</Hsp_qseq>
      <Hsp_hseq>KQVAQGIKFCH--DNGIAHRDLKPENVLISK-EGICKLTDFGISDWYHVIPHDYTSPVKTCQGMIGSPPYTPPEVMYFDAKKHYPEKFQKPYNPLAMDSYALGIMLITMINNIIPFIDSCNTDARFR</Hsp_hseq>
      <Hsp_midline>+Q+ +G+ F H  D  I HRDLK +N+ I+   G  K+ D G++                 + +IG+P +  PE MY   ++HY E         ++D YA G+ ++ M  +  P+ +  N    +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.4394</Hsp_bit-score>
      <Hsp_score>106</Hsp_score>
      <Hsp_evalue>1.47389e-06</Hsp_evalue>
      <Hsp_query-from>49</Hsp_query-from>
      <Hsp_query-to>408</Hsp_query-to>
      <Hsp_hit-from>160</Hsp_hit-from>
      <Hsp_hit-to>296</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>139</Hsp_align-len>
      <Hsp_qseq>KRFKQMKIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTG----------------SVKVGDLGLAT-LKRASFAKSVIGTPEFMAPE--MYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYR</Hsp_qseq>
      <Hsp_hseq>RRRRVFSIPSLKSILSQILAGLKHIHEHN--FFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVENKNPYTAYVSTRWYRSPEILLRSGYYSKPLDIWAFGCVAVEVTVFRALFPGANEIDQIWK</Hsp_hseq>
      <Hsp_midline>+R +   I  ++S   QIL GL  +H  +    HRDLK +NI IT  T                  +K+ D GLA  ++  +   + + T  + +PE  +   +Y + +D++AFG   +E+      +       QI++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YDL025C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:405344:407206:-1 gene:YDL025C transcript:YDL025C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RTK1 description:Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002183]</Hit_def>
  <Hit_accession>YDL025C</Hit_accession>
  <Hit_len>620</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.0542</Hsp_bit-score>
      <Hsp_score>105</Hsp_score>
      <Hsp_evalue>1.71817e-06</Hsp_evalue>
      <Hsp_query-from>88</Hsp_query-from>
      <Hsp_query-to>417</Hsp_query-to>
      <Hsp_hit-from>410</Hsp_hit-from>
      <Hsp_hit-to>524</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>118</Hsp_align-len>
      <Hsp_qseq>WCRQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKRASFAKS------VIGTPEFMAPEMYEE-HYDESV-DVYAFGMCMLEMATSEYPYSECQNAAQIYRRVT</Hsp_qseq>
      <Hsp_hseq>YFKQLCHGVNYLHSMG--LAHRDLKLDNCVVTK-DGILKLIDFGSAVVFQYPYEDTIVKSHGIVGSDPYLAPELLKQTSYDPRVADVWSIAIIFYCMVLKRFPWKAPKKSFNSFRLFT</Hsp_hseq>
      <Hsp_midline>+ +Q+  G+++LH+    + HRDLK DN  +T   G +K+ D G A + +  +  +      ++G+  ++APE+ ++  YD  V DV++  +    M    +P+   + +   +R  T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YPR106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:740061:741392:1 gene:YPR106W transcript:YPR106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ISR1 description:Predicted protein kinase; overexpression causes sensitivity to staurosporine, which is a potent inhibitor of protein kinase C [Source:SGD;Acc:S000006310]</Hit_def>
  <Hit_accession>YPR106W</Hit_accession>
  <Hit_len>443</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.0542</Hsp_bit-score>
      <Hsp_score>105</Hsp_score>
      <Hsp_evalue>1.80185e-06</Hsp_evalue>
      <Hsp_query-from>67</Hsp_query-from>
      <Hsp_query-to>387</Hsp_query-to>
      <Hsp_hit-from>253</Hsp_hit-from>
      <Hsp_hit-to>369</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>119</Hsp_align-len>
      <Hsp_qseq>KIKVMRSWCRQILKGLHFLHTRDPPIIHRDLKCDNIFITG----PTGSVKVGDLGLATLKRA----SFAKSVIGTPEFMAPEMYEEHYDE----SVDVYAFGMCMLEMATSEYPYSECQ</Hsp_qseq>
      <Hsp_hseq>KRKIWWRLMKQMIDALKSLKTNG--IIHGDIKTANILITEMHVLNGGHCKDFDFYLADFTSAFHINQTPTDLNTTVEYCAPELIDSSSDHVPTFESDLYAVGLCLLSFISQHEPYNELQ</Hsp_hseq>
      <Hsp_midline>K K+     +Q++  L  L T    IIH D+K  NI IT       G  K  D  LA    A         +  T E+ APE+ +   D       D+YA G+C+L   +   PY+E Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>44.669</Hsp_bit-score>
      <Hsp_score>104</Hsp_score>
      <Hsp_evalue>2.4368e-06</Hsp_evalue>
      <Hsp_query-from>94</Hsp_query-from>
      <Hsp_query-to>375</Hsp_query-to>
      <Hsp_hit-from>957</Hsp_hit-from>
      <Hsp_hit-to>1049</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>96</Hsp_align-len>
      <Hsp_qseq>RQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATLKRASFAKSVIGTPEFMAPEMY--EEHYDESVDVYAFGMCMLEMATSEYPY</Hsp_qseq>
      <Hsp_hseq>KQVVASIKHLH--DQGIVHRDIKDENV-IVDSHGFVKLIDFGSAAYIKSGPFDVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLYTIIYKENPY</Hsp_hseq>
      <Hsp_midline>+Q++  +  LH  D  I+HRD+K +N+ I    G VK+ D G A   ++      +GT ++ APE+     +  +  D++A G+ +  +   E PY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YKL198C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:68232:70220:-1 gene:YKL198C transcript:YKL198C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK1 description:Putative serine/threonine protein kinase; regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein; PTK1 has a paralog, PTK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001681]</Hit_def>
  <Hit_accession>YKL198C</Hit_accession>
  <Hit_len>662</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>43.5134</Hsp_bit-score>
      <Hsp_score>101</Hsp_score>
      <Hsp_evalue>5.38329e-06</Hsp_evalue>
      <Hsp_query-from>94</Hsp_query-from>
      <Hsp_query-to>381</Hsp_query-to>
      <Hsp_hit-from>311</Hsp_hit-from>
      <Hsp_hit-to>425</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>118</Hsp_align-len>
      <Hsp_qseq>RQILKGLHFLHTRDPPIIHRDLKCDNIFITGPTGSVKVGDLGLATL------KRASFAK---SVIGTPEFMAPEMY----EEHYD---------ESVDVYAFGMCMLEMATSEYPYSE</Hsp_qseq>
      <Hsp_hseq>KQVACGVKFCH--DQGIAHRDLKPENVLLS-PDGVCKLTDFGISDWYHTDPHDLSSPVKKCAGMIGSPPYAPPEVMFYDSKKHYDTELQQPYDPRALDCYGLGIILMTLVNNVIPFLE</Hsp_hseq>
      <Hsp_midline>+Q+  G+ F H  D  I HRDLK +N+ ++ P G  K+ D G++          +S  K    +IG+P +  PE+     ++HYD          ++D Y  G+ ++ +  +  P+ E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>83</Statistics_hsp-len>
      <Statistics_eff-space>208231496</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057104-RA transcript Note:&quot;Similar to Wnk3 Serine/threonine-protein kinase WNK3 (Mus musculus)&quot; offset:0 AED:0.06 eAED:0.06 QI:0|0.5|0.33|0.66|1|1|3|268|282</Iteration_query-def>
  <Iteration_query-len>1117</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>650084227</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057105-RA transcript Note:&quot;Similar to Smc1a Structural maintenance of chromosomes protein 1A (Mus musculus)&quot; offset:114 AED:0.04 eAED:0.04 QI:114|0.92|0.92|0.96|0.48|0.46|26|379|1262</Iteration_query-def>
  <Iteration_query-len>4282</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YFL008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:119429:123106:1 gene:YFL008W transcript:YFL008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMC1 description:Subunit of the multiprotein cohesin complex; essential protein involved in chromosome segregation and in double-strand DNA break repair; SMC chromosomal ATPase family member, binds DNA with a preference for DNA with secondary structure [Source:SGD;Acc:S000001886]</Hit_def>
  <Hit_accession>YFL008W</Hit_accession>
  <Hit_len>1225</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>407.527</Hsp_bit-score>
      <Hsp_score>1046</Hsp_score>
      <Hsp_evalue>3.40047e-121</Hsp_evalue>
      <Hsp_query-from>115</Hsp_query-from>
      <Hsp_query-to>3798</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>1225</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>353</Hsp_identity>
      <Hsp_positive>646</Hsp_positive>
      <Hsp_gaps>127</Hsp_gaps>
      <Hsp_align-len>1290</Hsp_align-len>
      <Hsp_qseq>MGYLQLIEVENFKSYQGKQTIG-PFTRFSAVIGPNGSGKSNLMDAISFVLGEQKRNLRVRSLRDLVY---------------GAPVGRPVATRAHVSMMYAEEGGSHTVFTRTII--GSTSEYRVDKRVLNFSEYSAQLAKRGILTKARNFLVFQGAVESIAMKTPKERTWLFEQISQSGELAAEYEQCKTAMLKANEDTQFNYHCKRNITXXXXXXXXXXXXXXNYRHLRDELASAHTQLNLFLLYHNEQQMKVLENELAGVGDQLDQQRALMSTTDDELRVRK----QEIGRLGRELQQVEKAIKAKEMDLGQSKPQYIKVKEN-----ISHRLRRMESTRQLLQNARAEWIRRKKDIDELERELVAVERARQDFEQLVGTQSQSED-FEIDESQVLEYYRLKEEVGRRAGGMTQE-LETFKRAQKADQEHLELETRKMKETQSKVKQKQQEYEDQQNRIEKIKQYIEKTRSAIEE---LDVEQV----SLTEQVEGARRRALEINDEVVALTAQLGDARTEQHENKRFKRRAEALDSLLRLFPGAIFGRLVNLCQPTHRKYQLAVTKVLGRNMEAIIVDTDSTARDCIRYLKEQRCEAEMFLPLDYLQVRPINERLRELRGAKLLMDVIKFDPPQVSRALQFACSNALVCETLEDARHIAFGSHVRQKCVSLDGTLFXXXXXXXXXXXDLRAKA-QRWDDK-------LVDXXXXXXXXXXXXXXVNLSIRRKEAD--LRQVQSQLHGMQTRLKYSRSDMEQTR--VKLQASLQEKSKLESQLANFEPHMDEVREGMAARDNEAEEVTEKMNKLEDEVFKDFCVEAGVANTREFEEVKLKWREEVTKKGSEFDNQKTRLGIQLDYERMQLKQEQSKVKMWXXXXXXXXXXXXCVKKDEQRYRDGVEHLLSEMHTLKNQL-------LAKQGEVTNKAQATEEVRRKLLAFSRQAVQLQNEVTALETKLEQQRNARHNLLLTCKLQDIKLPLRNGNLDSISQEALVCIKLGGTQPXXXXXXXXXXNSVYAREAAIEVDYRKLSRQYKEINREDEINRATDELNTQVTNLQTGMQHIVAPNMKATEKFENVRGKFLETTEALEESRKRSKQAQMAFNKVQRLRFDRFNGCLEHLSIAIDDIYKKLAQNNSAQAFLGPENA-------EEPYLDGINYNCVAPGKRYQPMDNLSGGEKTVAALALLFAIHSYRPSPFFVLDEIDAALDNTNIGKVANYIKEQSVENFQVIVISLKEELFARADALIGVYPEQGDCLISHVVTMDLSRFPD</Hsp_qseq>
      <Hsp_hseq>MGRLVGLELSNFKSYRGVTKVGFGESNFTSIIGPNGSGKSNMMDAISFVLGVRSNHLRSNILKDLIYRGVLNDENSDDYDNEGAASSNPQS--AYVKAFY-QKGNKLVELMRIISRNGDTS-YKIDGKTVSYKDYSIFLENENILIKAKNFLVFQGDVEQIAAQSPVELSRMFEEVSGSIQYKKEYEELKEKIEKLSKSATESIKNRRRIHGELKTYKEGINKNEEYRKQLDKKNELQKFQALWQLYHLEQQKEELTDKLSALNSEISSLKGKINNEMKSLQRSKSSFVKESAVISKQKSKLDYIFKDKEKLV--SDLRLIKVPQQAAGKRISHIEKRIESLQKDLQ-------RQKTYVERFETQLKVVTRSKEAFEEEIKQSARNYDKFKLNENDLKTYNCLHEKYLTEGGSILEEKIAVLNNDKREIQEELERFNKRADISKRRIT------EELSITGEKLDTQLNDLRVSLNEKNALHTERLHELKKLQSDIESANNQEYDLNFKLRETLVKIDDLSANQRETMKERKLRENIAMLKRFFPG-VKGLVHDLCHPKKEKYGLAVSTILGKNFDSVIVENLTVAQECIAFLKKQRAGTASFIPLDTIETELPTLSLPDSQDYILSINAIDYE-PEYEKAMQYVCGDSIICNTLNIAKDLKWKKGIRGKLVTIEGALI---HKAGLMTGGISGDANNRWDKEEYQSLMSLKDKLLIQIDELSNGQRSN-SIRAREVENSVSLLNSDIANLRTQVTQQKRSLDENRLEIKYHNDLIEKE--------IQPKITELKKKLDDLENTKDNLVKEKEALQNNIFKEFTSKIGFT-IKEYENHSGELMRQQSKELQQLQKQILTVENKLQFETDRLSTTQRRYEKAQKDLENAQVEMKSLEEQEYAIEMKIGSIESKLEEHKNHLDELQKKFVTKQSELNSSEDILEDMNSNLQVLKRERDGIKEDIEKFDLE-------RVTALKNCKISNINIPIS-------SETTIDDLPISSTD-----------NEAITISNSIDINYKGLPKKYKENN----TDSARKELEQKIHEVEEILNEL-QPNARALERYDEAEGRFEVINNETEQLKAEEKKILNQFLKIKKKRKELFEKTFDYVSDHLDAIYRELTKNPNSNVELAGGNASLTIEDEDEPFNAGIKYHATPPLKRFKDMEYLSGGEKTVAALALLFAINSYQPSPFFVLDEVDAALDITNVQRIAAYIRRHRNPDLQFIVISLKNTMFEKSDALVGVYRQQQEN-SSKIITLDLSNYAE</Hsp_hseq>
      <Hsp_midline>MG L  +E+ NFKSY+G   +G   + F+++IGPNGSGKSN+MDAISFVLG +  +LR   L+DL+Y               GA    P +  A+V   Y ++G       R I   G TS Y++D + +++ +YS  L    IL KA+NFLVFQG VE IA ++P E + +FE++S S +   EYE+ K  + K ++    +   +R I  E K  +    + E YR   D+         L+ LYH EQQ + L ++L+ +  ++   +  ++     L+  K    +E   + ++  +++   K KE  +  S  + IKV +      ISH  +R+ES ++ LQ       R+K  ++  E +L  V R+++ FE+ +   +++ D F+++E+ +  Y  L E+     G + +E +      ++  QE LE   ++   ++ ++       E+     EK+   +   R ++ E   L  E++     L   +E A  +  ++N ++     ++ D    Q E  + ++  E +  L R FPG + G + +LC P   KY LAV+ +LG+N +++IV+  + A++CI +LK+QR     F+PLD ++       L + +   L ++ I ++ P+  +A+Q+ C ++++C TL  A+ + +   +R K V+++G L          +  +   A  RWD +       L DKL  + ++L    R N SIR +E +  +  + S +  ++T++   +  +++ R  +K    L EK          +P + E+++ +   +N  + + ++   L++ +FK+F  + G    +E+E    +   + +K+  +   Q   +  +L +E  +L   Q + +     +   + E+  +++ E      +  + S++   KN L       + KQ E+ +     E++   L    R+   ++ ++   + +       R   L  CK+ +I +P+        S+  +  + +  T            N       +I+++Y+ L ++YKE N     + A  EL  ++  ++  +  +  PN +A E+++   G+F       E+ +   K+    F K+++ R + F    +++S  +D IY++L +N ++   L   NA       +EP+  GI Y+   P KR++ M+ LSGGEKTVAALALLFAI+SY+PSPFFVLDE+DAALD TN+ ++A YI+     + Q IVISLK  +F ++DAL+GVY +Q +   S ++T+DLS + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YLR086W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:302243:306499:1 gene:YLR086W transcript:YLR086W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMC4 description:Subunit of the condensin complex; condensin reorganizes chromosomes during both mitosis and meiosis; forms a subcomplex with Smc2p that has ATP-hydrolyzing and DNA-binding activity, but other condensin subunits are required for chromatin binding; required for tRNA gene clustering at the nucleolus; potential Cdc28p substrate [Source:SGD;Acc:S000004076]</Hit_def>
  <Hit_accession>YLR086W</Hit_accession>
  <Hit_len>1418</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>130.183</Hsp_bit-score>
      <Hsp_score>326</Hsp_score>
      <Hsp_evalue>1.08159e-30</Hsp_evalue>
      <Hsp_query-from>3307</Hsp_query-from>
      <Hsp_query-to>3735</Hsp_query-to>
      <Hsp_hit-from>1259</Hsp_hit-from>
      <Hsp_hit-to>1398</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>143</Hsp_align-len>
      <Hsp_qseq>VQRLRFDRFNGCLEHLSIAIDDIYKKLAQNNSAQAFLGPENAEEPYLDGINYNCVAPGKRYQPMDNLSGGEKTVAALALLFAIHSYRPSPFFVLDEIDAALDNTNIGKVANYIKEQSVENFQVIVISLKEELFARADALIGVY</Hsp_qseq>
      <Hsp_hseq>LKKKRFDEFMAGFNIISMTLKEMYQMITMGGNAELELV--DSLDPFSEGVTFSVMPPKKSWRNITNLSGGEKTLSSLALVFALHKYKPTPLYVMDEIDAALDFRNVSIVANYIKERT-KNAQFIVISLRNNMFELAQQLVGVY</Hsp_hseq>
      <Hsp_midline>+++ RFD F      +S+ + ++Y+ +    +A+  L   ++ +P+ +G+ ++ + P K ++ + NLSGGEKT+++LAL+FA+H Y+P+P +V+DEIDAALD  N+  VANYIKE++ +N Q IVISL+  +F  A  L+GVY</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>104.375</Hsp_bit-score>
      <Hsp_score>259</Hsp_score>
      <Hsp_evalue>7.51442e-23</Hsp_evalue>
      <Hsp_query-from>121</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>155</Hsp_hit-from>
      <Hsp_hit-to>314</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>YLQLIEVENFKSYQGKQTIGPF-TRFSAVIGPNGSGKSNLMDAISFVLGEQKRNLRVRSLRDLVYGA---PVGRPVATRAHVSMMYAEEGGSH--------TVFTRTII-GSTSEYRVDKRVLNFSEYSAQLAKRGILTKARNFLVFQGAVESIAMKTPK</Hsp_qseq>
      <Hsp_hseq>FINELVLENFKSYAGKQVVGPFHTSFSAVVGPNGSGKSNVIDSMLFVFGFRANKMRQDRLSDLIHKSEAFPSLQSCSVAVHFQYVIDESSGTSRIDEEKPGLIITRKAFKNNSSKYYINEKESSYTEVTKLLKNEGIDLDHKRFLILQGEVENIAQMKPK</Hsp_hseq>
      <Hsp_midline>++  + +ENFKSY GKQ +GPF T FSAV+GPNGSGKSN++D++ FV G +   +R   L DL++ +   P  +  +   H   +  E  G+          + TR     ++S+Y ++++  +++E +  L   GI    + FL+ QG VE+IA   PK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YFR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:216594:220106:-1 gene:YFR031C transcript:YFR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMC2 description:Subunit of the condensin complex; condensin reorganizes chromosomes during both mitosis and meiosis; essential SMC chromosomal ATPase family member that forms a subcomplex with Smc2p that has ATP-hydrolyzing and DNA-binding activity, but other condensin subunits are required for chromatin binding; required for clustering of tRNA genes at the nucleolus [Source:SGD;Acc:S000001927]</Hit_def>
  <Hit_accession>YFR031C</Hit_accession>
  <Hit_len>1170</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.559</Hsp_bit-score>
      <Hsp_score>179</Hsp_score>
      <Hsp_evalue>2.04441e-13</Hsp_evalue>
      <Hsp_query-from>139</Hsp_query-from>
      <Hsp_query-to>585</Hsp_query-to>
      <Hsp_hit-from>8</Hsp_hit-from>
      <Hsp_hit-to>167</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>168</Hsp_align-len>
      <Hsp_qseq>VENFKSYQGKQTIGPF-TRFSAVIGPNGSGKSNLMDAISFVLG-EQKRNLRVRSLRDLVYGAPVGRPVATRAHVSMMY--AEEGGSHTVFTRT---------IIGSTSEYRVD------KRVLNFSEYSAQLAKRGILTKARNFLVFQGAVESIAMKTPKERTWLFEQ</Hsp_qseq>
      <Hsp_hseq>IDGFKSYATRTVITDWDPQFNAITGLNGSGKSNILDAICFVLGIASMSTVRASSLQDLIYKR--GQAGVTKASVTIVFDNTDKSNSPIGFTNSPQISVTRQVVLGGTSKYLINGHRAPQQSVLQLFQ-SVQLN-----INNPNFLIMQGKITKVLNMKPSEILSLIEE</Hsp_hseq>
      <Hsp_midline>++ FKSY  +  I  +  +F+A+ G NGSGKSN++DAI FVLG      +R  SL+DL+Y    G+   T+A V++++   ++  S   FT +         ++G TS+Y ++      + VL   + S QL          NFL+ QG +  +    P E   L E+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>8.12263e-13</Hsp_evalue>
      <Hsp_query-from>3505</Hsp_query-from>
      <Hsp_query-to>3762</Hsp_query-to>
      <Hsp_hit-from>1084</Hsp_hit-from>
      <Hsp_hit-to>1168</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>86</Hsp_align-len>
      <Hsp_qseq>LSGGEKTVAALALLFAIHSYRPSPFFVLDEIDAALDNTNIGKVANYIKEQSVENFQVIVISLKEELFARADALIGVYPEQGDCLIS</Hsp_qseq>
      <Hsp_hseq>LSGGQRSLIALSLIMALLQFRPAPMYILDEVDAALDLSHTQNIGHLIKTR-FKGSQFIVVSLKEGMFANANRVFRTRFQDGTSVVS</Hsp_hseq>
      <Hsp_midline>LSGG++++ AL+L+ A+  +RP+P ++LDE+DAALD ++   + + IK +  +  Q IV+SLKE +FA A+ +     + G  ++S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YJL074C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:299157:302849:-1 gene:YJL074C transcript:YJL074C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMC3 description:Subunit of the multiprotein cohesin complex; required for sister chromatid cohesion in mitotic cells; also required, with Rec8p, for cohesion and recombination during meiosis; phylogenetically conserved SMC chromosomal ATPase family member [Source:SGD;Acc:S000003610]</Hit_def>
  <Hit_accession>YJL074C</Hit_accession>
  <Hit_len>1230</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>8.05769e-10</Hsp_evalue>
      <Hsp_query-from>3496</Hsp_query-from>
      <Hsp_query-to>3780</Hsp_query-to>
      <Hsp_hit-from>1123</Hsp_hit-from>
      <Hsp_hit-to>1213</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>95</Hsp_align-len>
      <Hsp_qseq>MDNLSGGEKTVAALALLFAIHSYRPSPFFVLDEIDAALDNTNIGKVANYIKEQSVENFQVIVISLKEELFARADALIGVYPEQGDCLISHVVTMD</Hsp_qseq>
      <Hsp_hseq>VEQLSGGQKTVCAIALILAIQMVDPASFYLFDEIDAALDKQYRTAVATLLKELS-KNAQFICTTFRTDMLQVADKFFRVKYENK---ISTVIEVN</Hsp_hseq>
      <Hsp_midline>++ LSGG+KTV A+AL+ AI    P+ F++ DEIDAALD      VA  +KE S +N Q I  + + ++   AD    V  E     IS V+ ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>102</Statistics_hsp-len>
      <Statistics_eff-space>2969148775</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057106-RA transcript Note:&quot;Similar to FBLN1 Fibulin-1 (Fragment) (Chlorocebus aethiops)&quot; offset:0 AED:0.35 eAED:0.35 QI:0|0|0|1|0.66|1|4|0|257</Iteration_query-def>
  <Iteration_query-len>774</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>88</Statistics_hsp-len>
      <Statistics_eff-space>396655390</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057107-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.47 eAED:1.00 QI:0|-1|0|1|-1|1|1|0|77</Iteration_query-def>
  <Iteration_query-len>234</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>50</Statistics_hsp-len>
      <Statistics_eff-space>72353876</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057108-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.37 eAED:1.00 QI:0|-1|0|1|-1|1|1|0|115</Iteration_query-def>
  <Iteration_query-len>348</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>77</Statistics_hsp-len>
      <Statistics_eff-space>93828813</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0036919-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.75 eAED:0.97 QI:0|0|0|1|0|0|3|56|113</Iteration_query-def>
  <Iteration_query-len>398</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>79</Statistics_hsp-len>
      <Statistics_eff-space>126811351</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057096-RA transcript Note:&quot;Similar to TIMP3 Metalloproteinase inhibitor 3 (Scyliorhinus torazame)&quot; offset:131 AED:0.01 eAED:0.01 QI:131|1|1|1|0.66|0.75|4|3176|143</Iteration_query-def>
  <Iteration_query-len>3739</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2573349715</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0027253-RA transcript Note:&quot;Similar to BRAF Serine/threonine-protein kinase B-raf (Gallus gallus)&quot; offset:0 AED:0.46 eAED:0.54 QI:0|0.77|0.6|1|0.77|0.8|10|0|527</Iteration_query-def>
  <Iteration_query-len>1584</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>1.726e-06</Hsp_evalue>
      <Hsp_query-from>883</Hsp_query-from>
      <Hsp_query-to>1023</Hsp_query-to>
      <Hsp_hit-from>415</Hsp_hit-from>
      <Hsp_hit-to>462</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>17</Hsp_identity>
      <Hsp_positive>30</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>48</Hsp_align-len>
      <Hsp_qseq>HNFVRKTYFTLAFCDFCRKLL-FQGFRCQTCGYKFHQRCSTEVPMMCV</Hsp_qseq>
      <Hsp_hseq>HHFVQKSFYNIMCCAYCGDFLRYTGFQCQDCKFLCHKKCYTNVVTKCI</Hsp_hseq>
      <Hsp_midline>H+FV+K+++ +  C +C   L + GF+CQ C +  H++C T V   C+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>995451478</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057098-RA transcript Note:&quot;Similar to Klhl12 Kelch-like protein 12 (Mus musculus)&quot; offset:0 AED:0.21 eAED:0.21 QI:0|0.6|0.63|1|0.7|0.81|11|1849|483</Iteration_query-def>
  <Iteration_query-len>3301</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2254067000</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057109-RA transcript Note:&quot;Similar to WNT7B Protein Wnt-7b (Gallus gallus)&quot; offset:0 AED:0.31 eAED:0.31 QI:0|-1|0|1|-1|1|1|0|166</Iteration_query-def>
  <Iteration_query-len>501</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>83</Statistics_hsp-len>
      <Statistics_eff-space>198766428</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057110-RA transcript Note:&quot;Similar to WNT7B Protein Wnt-7b (Gallus gallus)&quot; offset:0 AED:0.36 eAED:0.36 QI:0|0|0|0.66|1|1|3|0|202</Iteration_query-def>
  <Iteration_query-len>609</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>85</Statistics_hsp-len>
      <Statistics_eff-space>277661906</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0057111-RA transcript Note:&quot;Similar to Pphln1 Periphilin-1 (Mus musculus)&quot; offset:191 AED:0.06 eAED:0.06 QI:191|0.88|0.8|1|0.44|0.4|10|1398|537</Iteration_query-def>
  <Iteration_query-len>3203</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2179682789</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

