<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0030982-RA transcript Note:&quot;Similar to Hivep2 Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Rattus norvegicus)&quot; offset:1318 AED:1.00 eAED:1.00 QI:1318|0|0|0|0.09|0.08|12|1749|1317</BlastOutput_query-def>
  <BlastOutput_query-len>7021</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0030982-RA transcript Note:&quot;Similar to Hivep2 Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Rattus norvegicus)&quot; offset:1318 AED:1.00 eAED:1.00 QI:1318|0|0|0|0.09|0.08|12|1749|1317</Iteration_query-def>
  <Iteration_query-len>7021</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YPR013C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:584632:585585:-1 gene:YPR013C transcript:YPR013C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMR3 description:Putative zinc finger protein; YPR013C is not an essential gene [Source:SGD;Acc:S000006217]</Hit_def>
  <Hit_accession>YPR013C</Hit_accession>
  <Hit_len>317</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>2.28135e-09</Hsp_evalue>
      <Hsp_query-from>355</Hsp_query-from>
      <Hsp_query-to>543</Hsp_query-to>
      <Hsp_hit-from>246</Hsp_hit-from>
      <Hsp_hit-to>306</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>37</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>65</Hsp_align-len>
      <Hsp_qseq>RDGEDKLKKPGKYACSYCGRACAKPSVLKKHVRMHTGERPYPCL--ACGFSFKTKSNLYKHCKSH</Hsp_qseq>
      <Hsp_hseq>RISSTKLRK----QCPVCGKICSRPSTLKTHYLIHTGDTPFKCTWEGCTKSFNVKSNMLRHLKSH</Hsp_hseq>
      <Hsp_midline>R    KL+K     C  CG+ C++PS LK H  +HTG+ P+ C    C  SF  KSN+ +H KSH</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YNL027W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:579580:581616:1 gene:YNL027W transcript:YNL027W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CRZ1 description:Transcription factor, activates transcription of stress response genes; nuclear localization is positively regulated by calcineurin-mediated dephosphorylation; rapidly localizes to the nucleus under blue light stress; can be activated in stochastic pulses of nuclear localization in response to calcium [Source:SGD;Acc:S000004972]</Hit_def>
  <Hit_accession>YNL027W</Hit_accession>
  <Hit_len>678</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>5.55712e-08</Hsp_evalue>
      <Hsp_query-from>376</Hsp_query-from>
      <Hsp_query-to>546</Hsp_query-to>
      <Hsp_hit-from>564</Hsp_hit-from>
      <Hsp_hit-to>620</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>22</Hsp_identity>
      <Hsp_positive>31</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>57</Hsp_align-len>
      <Hsp_qseq>KKPGKYACSYCGRACAKPSVLKKHVRMHTGERPYPCLACGFSFKTKSNLYKHCKSHA</Hsp_qseq>
      <Hsp_hseq>KNPANFACDVCGKKFTRPYNLKSHLRTHTNERPFICSICGKAFARQHDRKRHEDLHT</Hsp_hseq>
      <Hsp_midline>K P  +AC  CG+   +P  LK H+R HT ERP+ C  CG +F  + +  +H   H </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YPR015C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:590283:591026:-1 gene:YPR015C transcript:YPR015C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Putative zinc finger transcription factor; binds DNA in sequence-specific manner; overexpression causes a cell cycle delay or arrest [Source:SGD;Acc:S000006219]</Hit_def>
  <Hit_accession>YPR015C</Hit_accession>
  <Hit_len>247</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>5.66071e-08</Hsp_evalue>
      <Hsp_query-from>397</Hsp_query-from>
      <Hsp_query-to>543</Hsp_query-to>
      <Hsp_hit-from>187</Hsp_hit-from>
      <Hsp_hit-to>237</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>32</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>51</Hsp_align-len>
      <Hsp_qseq>CSYCGRACAKPSVLKKHVRMHTGERPYPCL--ACGFSFKTKSNLYKHCKSH</Hsp_qseq>
      <Hsp_hseq>CPICGKVCSRPSTLRTHYLIHTGDTPFKCTWEHCNKSFNVKSNMLRHLRTH</Hsp_hseq>
      <Hsp_midline>C  CG+ C++PS L+ H  +HTG+ P+ C    C  SF  KSN+ +H ++H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YJL056C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:330431:333073:-1 gene:YJL056C transcript:YJL056C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZAP1 description:Zinc-regulated transcription factor; binds to zinc-responsive promoters to induce transcription of certain genes in presence of zinc, represses other genes in low zinc; regulates its own transcription; contains seven zinc-finger domains [Source:SGD;Acc:S000003592]</Hit_def>
  <Hit_accession>YJL056C</Hit_accession>
  <Hit_len>880</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>1.36027e-07</Hsp_evalue>
      <Hsp_query-from>391</Hsp_query-from>
      <Hsp_query-to>543</Hsp_query-to>
      <Hsp_hit-from>796</Hsp_hit-from>
      <Hsp_hit-to>846</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>25</Hsp_identity>
      <Hsp_positive>29</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>51</Hsp_align-len>
      <Hsp_qseq>YACSYCGRACAKPSVLKKHVRMHTGERPYPCLACGFSFKTKSNLYKHCKSH</Hsp_qseq>
      <Hsp_hseq>YKCHICNKKFAISSSLKIHIRTHTGEKPLQCKICGKRFNESSNLSKHIKTH</Hsp_hseq>
      <Hsp_midline>Y C  C +  A  S LK H+R HTGE+P  C  CG  F   SNL KH K+H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YOR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:534075:536819:1 gene:YOR113W transcript:YOR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AZF1 description:Zinc-finger transcription factor; involved in diauxic shift; in the presence of glucose, activates transcription of genes involved in growth and carbon metabolism; in nonfermentable carbon sources, activates transcription of genes involved in maintenance of cell wall integrity; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000005639]</Hit_def>
  <Hit_accession>YOR113W</Hit_accession>
  <Hit_len>914</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>2.30673e-07</Hsp_evalue>
      <Hsp_query-from>391</Hsp_query-from>
      <Hsp_query-to>543</Hsp_query-to>
      <Hsp_hit-from>621</Hsp_hit-from>
      <Hsp_hit-to>671</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>28</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>51</Hsp_align-len>
      <Hsp_qseq>YACSYCGRACAKPSVLKKHVRMHTGERPYPCLACGFSFKTKSNLYKHCKSH</Hsp_qseq>
      <Hsp_hseq>FVCDYCGKRFTQGGNLRTHERLHTGEKPYSCDICDKKFSRKGNLAAHLVTH</Hsp_hseq>
      <Hsp_midline>+ C YCG+   +   L+ H R+HTGE+PY C  C   F  K NL  H  +H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YER130C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:421115:422446:-1 gene:YER130C transcript:YER130C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:COM2 description:Transcription factor that binds IME1 Upstream Activation Signal (UAS)ru; COM2 transcription is regulated by Haa1p, Sok2p and Zap1p transcriptional activators; may bind the IME1 promoter under all growth conditions to negatively regulate its transcription in the absence of a positive regulator that binds more effectively; repressor activity may depend on phosphorylation by PKA; C. albicans homolog (MNL1) plays a role in adaptation to stress [Source:SGD;Acc:S000000932]</Hit_def>
  <Hit_accession>YER130C</Hit_accession>
  <Hit_len>443</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>7.30043e-07</Hsp_evalue>
      <Hsp_query-from>388</Hsp_query-from>
      <Hsp_query-to>546</Hsp_query-to>
      <Hsp_hit-from>388</Hsp_hit-from>
      <Hsp_hit-to>441</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>20</Hsp_identity>
      <Hsp_positive>31</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>54</Hsp_align-len>
      <Hsp_qseq>KYACSYCGRACAKPSVLKKHVR-MHTGERPYPCLACGFSFKTKSNLYKHCKSHA</Hsp_qseq>
      <Hsp_hseq>QFGCEFCDRRFKRQEHLKRHVRSLHMCEKPFTCHICNKNFSRSDNLNQHVKTHA</Hsp_hseq>
      <Hsp_midline>++ C +C R   +   LK+HVR +H  E+P+ C  C  +F    NL +H K+HA</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YDR216W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:895035:899006:1 gene:YDR216W transcript:YDR216W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ADR1 description:Carbon source-responsive zinc-finger transcription factor; required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization [Source:SGD;Acc:S000002624]</Hit_def>
  <Hit_accession>YDR216W</Hit_accession>
  <Hit_len>1323</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>2.95864e-06</Hsp_evalue>
      <Hsp_query-from>391</Hsp_query-from>
      <Hsp_query-to>537</Hsp_query-to>
      <Hsp_hit-from>104</Hsp_hit-from>
      <Hsp_hit-to>152</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>20</Hsp_identity>
      <Hsp_positive>27</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>49</Hsp_align-len>
      <Hsp_qseq>YACSYCGRACAKPSVLKKHVRMHTGERPYPCLACGFSFKTKSNLYKHCK</Hsp_qseq>
      <Hsp_hseq>FVCEVCTRAFARQEHLKRHYRSHTNEKPYPCGLCNRCFTRRDLLIRHAQ</Hsp_hseq>
      <Hsp_midline>+ C  C RA A+   LK+H R HT E+PYPC  C   F  +  L +H +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YKL062W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:323228:325120:1 gene:YKL062W transcript:YKL062W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MSN4 description:Stress-responsive transcriptional activator; activated in stochastic pulses of nuclear localization in response to various stress conditions; binds DNA at stress response elements of responsive genes, inducing gene expression; involved in diauxic shift [Source:SGD;Acc:S000001545]</Hit_def>
  <Hit_accession>YKL062W</Hit_accession>
  <Hit_len>630</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>3.07371e-06</Hsp_evalue>
      <Hsp_query-from>334</Hsp_query-from>
      <Hsp_query-to>543</Hsp_query-to>
      <Hsp_hit-from>554</Hsp_hit-from>
      <Hsp_hit-to>624</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>22</Hsp_identity>
      <Hsp_positive>36</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>71</Hsp_align-len>
      <Hsp_qseq>RRRRHYCRDGEDKLKKPGKYACSYCGRACAKPSVLKKHVR-MHTGERPYPCLACGFSFKTKSNLYKHCKSH</Hsp_qseq>
      <Hsp_hseq>RKRKSITTIDPNNYDKNKPFKCKDCEKAFRRSEHLKRHIRSVHSTERPFACMFCEKKFSRSDNLSQHLKTH</Hsp_hseq>
      <Hsp_midline>R+R+       +   K   + C  C +A  +   LK+H+R +H+ ERP+ C+ C   F    NL +H K+H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>106</Statistics_hsp-len>
      <Statistics_eff-space>4947119278</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056609-RA transcript Note:&quot;Similar to LDAH Lipid droplet-associated hydrolase (Gallus gallus)&quot; offset:138 AED:0.04 eAED:0.04 QI:138|1|1|1|0.16|0.14|7|1068|332</Iteration_query-def>
  <Iteration_query-len>2205</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YPR147C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:825645:826559:-1 gene:YPR147C transcript:YPR147C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein of unknown function; may have a role in lipid metabolism, based on localization to lipid droplets; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS [Source:SGD;Acc:S000006351]</Hit_def>
  <Hit_accession>YPR147C</Hit_accession>
  <Hit_len>304</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>2.02812e-12</Hsp_evalue>
      <Hsp_query-from>265</Hsp_query-from>
      <Hsp_query-to>1077</Hsp_query-to>
      <Hsp_hit-from>20</Hsp_hit-from>
      <Hsp_hit-to>293</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>126</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>292</Hsp_align-len>
      <Hsp_qseq>PGYDGQGPPQILFMLIPGNPGVMDYYRTFMAGLYQAFKGQYSVWGISHAGHCVPPPDLEAHQNADEHPDVFGLDGQVEHKRAFLREHVGPAVRLVLIGHSIGCHIILEILKRDPQLKVIKSV-LLFPTIERMAESPSGRVMTPILCRLRYLAYPP------ILCLSFLLPLRAKTLLASVALWASGLGPKTDPNAVSASLNLFSVHCAANSMYMASQEMYQVT------ERDNVTIQEHLDKLIFYYGMSDHWCP-------VEYYHD-MKRDFPAGDVRLCEKGIRHAFVL</Hsp_qseq>
      <Hsp_hseq>PTVTKSGEDAPLLVWIPGNPGLLYYYQEMLHHLHLK-HPDWEILGISHAGMT-----LNAHSNTP----IFSLQDQVDHQVEVINNFSCKNRKIIIMGHSVGAYIVQKVCLSNKLVGSVQKVGLVTPTVMDIHTSEMGIKMT---AALRYI--PPLAHVVSLFSYIFFYWILSEGFSRFIIDKFMGCGSTGYQAVLSTRIFLTHRQFVRQSLGLAAQEMEEITTNWEFQDRFINYCEENGISIWFLFSSNDHWVSGKTRSHLSDYYKDKVKQERLKIDV---TDKIPHSFVV</Hsp_hseq>
      <Hsp_midline>P     G    L + IPGNPG++ YY+  +  L+      + + GISHAG       L AH N      +F L  QV+H+   +        +++++GHS+G +I+ ++   +  +  ++ V L+ PT+  +  S  G  MT     LRY+  PP      +    F   + ++     +     G G       +S  + L        S+ +A+QEM ++T      +R     +E+   + F +  +DHW          +YY D +K++    DV      I H+FV+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1450727146</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0017016-RA transcript Note:&quot;Similar to TDRD15 Tudor domain-containing protein 15 (Homo sapiens)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.4|0.33|6|0|1105</Iteration_query-def>
  <Iteration_query-len>3318</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2267591402</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0030979-RA transcript Note:&quot;Similar to Tdrd6 Tudor domain-containing protein 6 (Mus musculus)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0|0.5|2|0|1562</Iteration_query-def>
  <Iteration_query-len>4689</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3262029820</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0041060-RA transcript Note:&quot;Similar to PLEC Plectin (Homo sapiens)&quot; offset:0 AED:0.59 eAED:0.65 QI:0|0.2|0.33|0.66|0.6|0.83|6|0|206</Iteration_query-def>
  <Iteration_query-len>621</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>85</Statistics_hsp-len>
      <Statistics_eff-space>287074174</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056613-RA transcript Note:&quot;Similar to Prim2 DNA primase large subunit (Rattus norvegicus)&quot; offset:315 AED:0.28 eAED:0.28 QI:315|0.8|1|1|0.5|0.54|11|2034|461</Iteration_query-def>
  <Iteration_query-len>3735</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YKL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:353493:355079:1 gene:YKL045W transcript:YKL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRI2 description:Subunit of DNA primase; DNA primase is required for DNA synthesis and double-strand break repair [Source:SGD;Acc:S000001528]</Hit_def>
  <Hit_accession>YKL045W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>175.637</Hsp_bit-score>
      <Hsp_score>444</Hsp_score>
      <Hsp_evalue>4.73993e-47</Hsp_evalue>
      <Hsp_query-from>385</Hsp_query-from>
      <Hsp_query-to>1446</Hsp_query-to>
      <Hsp_hit-from>55</Hsp_hit-from>
      <Hsp_hit-to>507</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>133</Hsp_identity>
      <Hsp_positive>201</Hsp_positive>
      <Hsp_gaps>117</Hsp_gaps>
      <Hsp_align-len>462</Hsp_align-len>
      <Hsp_qseq>YPHVLQLYLRPPLGSVSLVEFEALAVQRLRLLKSVERIGVLFMKGTENYDXXXXXXXXXXXFPYRDNITLIEVDDQEPRKRDHISHFILRLAYCQSEDLRRWFIQQEMDLFRFRFLQQTSESVTSFLN--------------------------------QNNLTYE-------------SVPFTDALELVRSRKVFVRRGMAFIPQRDLVTIVLN----------------------------------------DFRQNLSRALTH---------------AARSFPLCMRQVHSAXXXXXXXXXXXXMQYGLYLKGIGLTLQQSLEFWRAEFALG--VGADKFDKSYAYNVRHNYGKEGKRTDYTPYSCMKIIMTNMPAQGDYHGCPFRHTEPELLKMKLLAYKVPSADISQILDLVKGMHYQLACQKYFEVTHKVEDTSFALN------HPNEYFEES</Hsp_qseq>
      <Hsp_hseq>YESKLSFYDLPPQGEITLEQFEIWAIDRLKILLEIESC-LSRNKSIKEIETIIK--------PQFQKLLPFNTESLEDRKKDYYSHFILRLCFCRSKELREKFVRAETFLFKIRFNMLTSTDQTKFVQSLDLPLLQFISNEEKAELSHQLYQTVSASLQFQLNLNEEHQRKQYFQQEKFIKLPFENVIELVGNRLVFLKDGYAYLPQFQQLNLLSNEFASKLNQELIKTYQYLPRLNEDDRLLPILNHLSSGYTIADFNQQKANQFSENVDDEINAQSVWSEEISSNYPLCIKNLMEGLKKNHHLRYYGRQQLSLFLKGIGLSADEALKFWSEAFTRNGNMTMEKFNKEYRYSFRHNYGLEGNRINYKPWDCHTILSKPRPGRGDYHGCPFRDWSHERLSAELRSMKLTQAQIISVLDSCQKGEYTIACTKVFEMTHNSASADLEIGEQTHIAHPNLYFERS</Hsp_hseq>
      <Hsp_midline>Y   L  Y  PP G ++L +FE  A+ RL++L  +E   +   K  +  +  ++        P    +     +  E RK+D+ SHFILRL +C+S++LR  F++ E  LF+ RF   TS   T F+                                 Q NL  E              +PF + +ELV +R VF++ G A++PQ   + ++ N                                        DF Q  +   +                 + ++PLC++ +   L+++HHLR+ GR Q  L+LKGIGL+  ++L+FW   F     +  +KF+K Y Y+ RHNYG EG R +Y P+ C  I+    P +GDYHGCPFR    E L  +L + K+  A I  +LD  +   Y +AC K FE+TH        +       HPN YFE S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2571102248</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0031850-RA transcript Note:&quot;Similar to Khdrbs2 KH domain-containing, RNA-binding, signal transduction-associated protein 2 (Rattus norvegicus)&quot; offset:0 AED:0.15 eAED:0.15 QI:0|0.16|0.14|0.71|0.16|0.42|7|824|227</Iteration_query-def>
  <Iteration_query-len>1508</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YLR116W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:380822:382252:1 gene:YLR116W transcript:YLR116W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MSL5 description:Component of commitment complex; which defines first step in splicing pathway; essential protein that interacts with Mud2p and Prp40p, forming a bridge between the intron ends; also involved in nuclear retention of pre-mRNA; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000004106]</Hit_def>
  <Hit_accession>YLR116W</Hit_accession>
  <Hit_len>476</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.2098</Hsp_bit-score>
      <Hsp_score>108</Hsp_score>
      <Hsp_evalue>8.42836e-06</Hsp_evalue>
      <Hsp_query-from>73</Hsp_query-from>
      <Hsp_query-to>279</Hsp_query-to>
      <Hsp_hit-from>163</Hsp_hit-from>
      <Hsp_hit-to>228</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>25</Hsp_identity>
      <Hsp_positive>42</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>70</Hsp_align-len>
      <Hsp_qseq>NFVGKLLGPQGNSLKRLQAETGTKMSILGKGCMRDKAKEEELRRGGEAKYAPLQERLHVL-IEDYNDEIR</Hsp_qseq>
      <Hsp_hseq>NFVGLLLGPRGRTLRKLQEDSNCKIAIRGRGSVKEGKNASDLPPGAMN----FEDPLHCLIIADSEDKIQ</Hsp_hseq>
      <Hsp_midline>NFVG LLGP+G +L++LQ ++  K++I G+G +++     +L  G        ++ LH L I D  D+I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>935816136</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056615-RA transcript Note:&quot;Similar to eef1as Elongation factor 1-alpha, somatic form (Xenopus laevis)&quot; offset:1664 AED:0.09 eAED:0.09 QI:1664|0.83|1|1|0.83|0.71|7|3305|364</Iteration_query-def>
  <Iteration_query-len>6064</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YPR080W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:700594:701970:1 gene:YPR080W transcript:YPR080W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TEF1 description:Translational elongation factor EF-1 alpha; in the GTP-bound active form, binds to and delivers aminoacylated tRNA to the A-site of ribosomes for elongation of nascent polypeptides; associates with vacuolar Rho1p GTPase; may also have a role in tRNA re-export from the nucleus; TEF1 has a paralog, TEF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006284]</Hit_def>
  <Hit_accession>YPR080W</Hit_accession>
  <Hit_len>458</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>407.527</Hsp_bit-score>
      <Hsp_score>1046</Hsp_score>
      <Hsp_evalue>1.44795e-127</Hsp_evalue>
      <Hsp_query-from>1965</Hsp_query-from>
      <Hsp_query-to>2696</Hsp_query-to>
      <Hsp_hit-from>198</Hsp_hit-from>
      <Hsp_hit-to>441</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>194</Hsp_identity>
      <Hsp_positive>212</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>244</Hsp_align-len>
      <Hsp_qseq>NMITGTSQMPWFKGWKVERKDGNASGTTLLEALDAILPPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALTEAVPGDNVGFNVKNVSVKDVRRGNVAGDSKNDPPMEAGVFTAQVIVLNHPGQINAGYSPVVDCHTAHIACKFAELKEKIDRRSGKKLEDNPKFLKSGDAAMVDMVPGKPMCVESFSDYPPLGRFAVRDMRQTVAVGVIKAVEK</Hsp_qseq>
      <Hsp_hseq>NMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLGRFAVRDMRQTVAVGVIKSVDK</Hsp_hseq>
      <Hsp_midline>NMI  T+  PW+KGW+ E K G   G TLLEA+DAI  PSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGV+KPGMVVTFAP  VTTEVKSVEMHHE L + VPGDNVGFNVKNVSVK++RRGNV GD+KNDPP     F A VIVLNHPGQI+AGYSPV+DCHTAHIAC+F EL EK DRRSGKKLED+PKFLKSGDAA+V  VP KPMCVE+FS+YPPLGRFAVRDMRQTVAVGVIK+V+K</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>213.001</Hsp_bit-score>
      <Hsp_score>541</Hsp_score>
      <Hsp_evalue>3.94174e-60</Hsp_evalue>
      <Hsp_query-from>1665</Hsp_query-from>
      <Hsp_query-to>1988</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>108</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>100</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>108</Hsp_align-len>
      <Hsp_qseq>MGKEKTHINIVVIGHVDSGKSTSTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETQKYYVTIIDAPGHRDFIKNMITGTSQ</Hsp_qseq>
      <Hsp_hseq>MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQ</Hsp_hseq>
      <Hsp_midline>MGKEK+HIN+VVIGHVDSGKST+TGHLIYKCGGIDKRTIEKFEKEAAE+GKGSFKYAWVLDKLKAERERGITIDI+LWKFET KY VT+IDAPGHRDFIKNMITGTSQ</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YBR118W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:477671:479047:1 gene:YBR118W transcript:YBR118W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TEF2 description:Translational elongation factor EF-1 alpha; in the GTP-bound active form, binds to and delivers aminoacylated tRNA to the A-site of ribosomes for elongation of nascent polypeptides; associates with vacuolar Rho1p GTPase; TEF2-RFP levels increase during replicative aging; may also have a role in tRNA re-export from the nucleus; TEF2 has a paralog, TEF1, that arose from the whole genome duplication [Source:SGD;Acc:S000000322]</Hit_def>
  <Hit_accession>YBR118W</Hit_accession>
  <Hit_len>458</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>407.527</Hsp_bit-score>
      <Hsp_score>1046</Hsp_score>
      <Hsp_evalue>1.44795e-127</Hsp_evalue>
      <Hsp_query-from>1965</Hsp_query-from>
      <Hsp_query-to>2696</Hsp_query-to>
      <Hsp_hit-from>198</Hsp_hit-from>
      <Hsp_hit-to>441</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>194</Hsp_identity>
      <Hsp_positive>212</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>244</Hsp_align-len>
      <Hsp_qseq>NMITGTSQMPWFKGWKVERKDGNASGTTLLEALDAILPPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALTEAVPGDNVGFNVKNVSVKDVRRGNVAGDSKNDPPMEAGVFTAQVIVLNHPGQINAGYSPVVDCHTAHIACKFAELKEKIDRRSGKKLEDNPKFLKSGDAAMVDMVPGKPMCVESFSDYPPLGRFAVRDMRQTVAVGVIKAVEK</Hsp_qseq>
      <Hsp_hseq>NMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLGRFAVRDMRQTVAVGVIKSVDK</Hsp_hseq>
      <Hsp_midline>NMI  T+  PW+KGW+ E K G   G TLLEA+DAI  PSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGV+KPGMVVTFAP  VTTEVKSVEMHHE L + VPGDNVGFNVKNVSVK++RRGNV GD+KNDPP     F A VIVLNHPGQI+AGYSPV+DCHTAHIAC+F EL EK DRRSGKKLED+PKFLKSGDAA+V  VP KPMCVE+FS+YPPLGRFAVRDMRQTVAVGVIK+V+K</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>213.001</Hsp_bit-score>
      <Hsp_score>541</Hsp_score>
      <Hsp_evalue>3.94174e-60</Hsp_evalue>
      <Hsp_query-from>1665</Hsp_query-from>
      <Hsp_query-to>1988</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>108</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>100</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>108</Hsp_align-len>
      <Hsp_qseq>MGKEKTHINIVVIGHVDSGKSTSTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETQKYYVTIIDAPGHRDFIKNMITGTSQ</Hsp_qseq>
      <Hsp_hseq>MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQ</Hsp_hseq>
      <Hsp_midline>MGKEK+HIN+VVIGHVDSGKST+TGHLIYKCGGIDKRTIEKFEKEAAE+GKGSFKYAWVLDKLKAERERGITIDI+LWKFET KY VT+IDAPGHRDFIKNMITGTSQ</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YKR084C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:597055:598890:-1 gene:YKR084C transcript:YKR084C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HBS1 description:GTPase with similarity to translation release factors; together with binding partner Dom34p, facilitates ribosomal subunit dissociation and peptidyl-tRNA release when translation is stalled, particularly in 3&apos; UTRs; genetically implicated in mRNA no-go decay; HBS1 has a paralog, SKI7, that arose from the whole genome duplication [Source:SGD;Acc:S000001792]</Hit_def>
  <Hit_accession>YKR084C</Hit_accession>
  <Hit_len>611</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>116.316</Hsp_bit-score>
      <Hsp_score>290</Hsp_score>
      <Hsp_evalue>9.06224e-27</Hsp_evalue>
      <Hsp_query-from>1683</Hsp_query-from>
      <Hsp_query-to>1988</Hsp_query-to>
      <Hsp_hit-from>167</Hsp_hit-from>
      <Hsp_hit-to>268</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>102</Hsp_align-len>
      <Hsp_qseq>HINIVVIGHVDSGKSTSTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETQKYYVTIIDAPGHRDFIKNMITGTSQ</Hsp_qseq>
      <Hsp_hseq>HLSFVVLGHVDAGKSTLMGRLLYDLNIVNQSQLRKLQRESETMGKSSFKFAWIMDQTNEERERGVTVSICTSHFSTHRANFTIVDAPGHRDFVPNAIMGISQ</Hsp_hseq>
      <Hsp_midline>H++ VV+GHVD+GKST  G L+Y    +++  + K ++E+  MGK SFK+AW++D+   ERERG+T+ I    F T +   TI+DAPGHRDF+ N I G SQ</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YDR172W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:808324:810381:1 gene:YDR172W transcript:YDR172W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SUP35 description:Translation termination factor eRF3; has a role in mRNA deadenylation and decay; altered protein conformation creates the [PSI(+)] prion that modifies cellular fitness, alters translational fidelity by affecting reading frame selection, and results in a nonsense suppressor phenotype; many stress-response genes are repressed in the presence of [PSI(+)] [Source:SGD;Acc:S000002579]</Hit_def>
  <Hit_accession>YDR172W</Hit_accession>
  <Hit_len>685</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>111.309</Hsp_bit-score>
      <Hsp_score>277</Hsp_score>
      <Hsp_evalue>3.94057e-25</Hsp_evalue>
      <Hsp_query-from>1677</Hsp_query-from>
      <Hsp_query-to>1988</Hsp_query-to>
      <Hsp_hit-from>258</Hsp_hit-from>
      <Hsp_hit-to>361</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>104</Hsp_align-len>
      <Hsp_qseq>KTHINIVVIGHVDSGKSTSTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETQKYYVTIIDAPGHRDFIKNMITGTSQ</Hsp_qseq>
      <Hsp_hseq>KDHVSLIFMGHVDAGKSTMGGNLLYLTGSVDKRTIEKYEREAKDAGRQGWYLSWVMDTNKEERNDGKTIEVGKAYFETEKRRYTILDAPGHKMYVSEMIGGASQ</Hsp_hseq>
      <Hsp_midline>K H++++ +GHVD+GKST  G+L+Y  G +DKRTIEK+E+EA + G+  +  +WV+D  K ER  G TI++    FET+K   TI+DAPGH+ ++  MI G SQ</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>109.383</Hsp_bit-score>
      <Hsp_score>272</Hsp_score>
      <Hsp_evalue>1.84271e-24</Hsp_evalue>
      <Hsp_query-from>1986</Hsp_query-from>
      <Hsp_query-to>2681</Hsp_query-to>
      <Hsp_hit-from>463</Hsp_hit-from>
      <Hsp_hit-to>680</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>233</Hsp_align-len>
      <Hsp_qseq>QMPWFKGWKVERKDGNASGTTLLEALDAILPPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALTE-AVPGDNVGFNVKNVSVKDVRRGNVAGDSKNDPPMEAGVFTAQVIVLNHPGQINAGYSPVVDCHTAHIACKFAELKEKIDRRSGKKLEDNPKFLKSGDAAMVDMVPGKPMCVESFSDYPPLGRFAVRDMRQTVAVGVI</Hsp_qseq>
      <Hsp_hseq>ECPWY------------TGPTLLEYLDTMNHVDRHINAPFMLPI--AAKMKDLGTIVEGKIESGHIKKGQSTLLMPNKTAVEIQNIYNETENEVDMAMCGEQVKLRIKGVEEEDISPGFVLTSPKN-PIKSVTKFVAQIAIVELKSIIAAGFSCVMHVHTAIEEVHIVKLLHKLEKGTNRKSKKPPAFAKKGMKVIAVLETEAPVCVETYQDYPQLGRFTLRDQGTTIAIGKI</Hsp_hseq>
      <Hsp_midline>+ PW+            +G TLLE LD +    R  + P  LP+    K+  +GT+  G++E+G +K G      P     E++++    E   + A+ G+ V   +K V  +D+  G V    KN P      F AQ+ ++     I AG+S V+  HTA       +L  K+++ + +K +  P F K G   +  +    P+CVE++ DYP LGRF +RD   T+A+G I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YOR187W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:684030:685343:1 gene:YOR187W transcript:YOR187W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TUF1 description:Mitochondrial translation elongation factor Tu (EF-Tu); involved in fundamental pathway of mtDNA homeostasis; comprises both GTPase and guanine nucleotide exchange factor activities, while these activities are found in separate proteins in S. pombe and humans; rare mutations in human mitochondrial elongation factor Tu (EFTu) associated with severe lactic acidosis, rapidly progressive fatal encephalopathy, severe infantile macrocystic leukodystrophy with micropolygyria [Source:SGD;Acc:S000005713]</Hit_def>
  <Hit_accession>YOR187W</Hit_accession>
  <Hit_len>437</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.0258</Hsp_bit-score>
      <Hsp_score>188</Hsp_score>
      <Hsp_evalue>9.06654e-15</Hsp_evalue>
      <Hsp_query-from>1671</Hsp_query-from>
      <Hsp_query-to>1991</Hsp_query-to>
      <Hsp_hit-from>44</Hsp_hit-from>
      <Hsp_hit-to>135</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>107</Hsp_align-len>
      <Hsp_qseq>KEKTHINIVVIGHVDSGKSTSTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETQKYYVTIIDAPGHRDFIKNMITGTSQM</Hsp_qseq>
      <Hsp_hseq>RSKPHVNIGTIGHVDHGKTTLTAAIT---------------KTLAAKGGANFLDYAAIDKAPEERARGITISTAHVEYETAKRHYSHVDCPGHADYIKNMITGAAQM</Hsp_hseq>
      <Hsp_midline>+ K H+NI  IGHVD GK+T T  +                K  A  G  +F     +DK   ER RGITI  +  ++ET K + + +D PGH D+IKNMITG +QM</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>75.0998</Hsp_bit-score>
      <Hsp_score>183</Hsp_score>
      <Hsp_evalue>3.55805e-14</Hsp_evalue>
      <Hsp_query-from>2049</Hsp_query-from>
      <Hsp_query-to>2690</Hsp_query-to>
      <Hsp_hit-from>230</Hsp_hit-from>
      <Hsp_hit-to>435</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>235</Hsp_align-len>
      <Hsp_qseq>LLEALDAILP-PSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVT---TEVKSVEMHHEALTEAVPGDNVGFNVKNVSVKDVRRGNVAGDSKNDPPMEAGVFTAQVIVLNHPGQINAGYSPVVDCHTAHIACKFAELKEKIDRRSGKKLEDNPK-FLKSGDAAMV------------DMVPGKPMCVESFSDYP-PL---GRFAVRDMRQTVAVGVIKAV</Hsp_qseq>
      <Hsp_hseq>LLDAVDEYIPTPERDLNKPFLMPVEDIFSISGRGTVVTGRVERGNLKKGEELEIVGHNSTPLKTTVTGIEMFRKELDSAMAGDNAGVLLRGIRRDQLKRG---------------------MVLAKPGTVKA--------HTKILASLYILSKEEGGRHSGFGENYRPQMFIRTADVTVVMRFPKEVEDHSMQVMPGDNVEMECDLIHPTPLEVGQRFNIREGGRTVGTGLITRI</Hsp_hseq>
      <Hsp_midline>LL+A+D  +P P R  +KP  +P++D++ I G GTV  GRVE G LK G  +     N T   T V  +EM  + L  A+ GDN G  ++ +    ++RG                     +VL  PG + A        HT  +A  +   KE+  R SG      P+ F+++ D  +V             ++PG  + +E    +P PL    RF +R+  +TV  G+I  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YDR385W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1243230:1245758:1 gene:YDR385W transcript:YDR385W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:EFT2 description:Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin; EFT2 has a paralog, EFT1, that arose from the whole genome duplication [Source:SGD;Acc:S000002793]</Hit_def>
  <Hit_accession>YDR385W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>6.68278e-07</Hsp_evalue>
      <Hsp_query-from>1659</Hsp_query-from>
      <Hsp_query-to>1958</Hsp_query-to>
      <Hsp_hit-from>11</Hsp_hit-from>
      <Hsp_hit-to>111</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>116</Hsp_align-len>
      <Hsp_qseq>SIMGKEKTHINIVVIGHVDSGKSTSTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITID---ISLW-------------KFETQKYYVTIIDAPGHRDF</Hsp_qseq>
      <Hsp_hseq>SLMDKVTNVRNMSVIAHVDHGKSTLTDSLVQRAGII----------SAAKAGEARFT-----DTRKDEQERGITIKSTAISLYSEMSDEDVKEIKQKTDGNSFLINLIDSPGHVDF</Hsp_hseq>
      <Hsp_midline>S+M K     N+ VI HVD GKST T  L+ + G I           AA+ G+  F      D  K E+ERGITI    ISL+             K +   + + +ID+PGH DF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YOR133W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:575098:577626:1 gene:YOR133W transcript:YOR133W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:EFT1 description:Elongation factor 2 (EF-2), also encoded by EFT2; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin; EFT1 has a paralog, EFT2, that arose from the whole genome duplication [Source:SGD;Acc:S000005659]</Hit_def>
  <Hit_accession>YOR133W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>6.68278e-07</Hsp_evalue>
      <Hsp_query-from>1659</Hsp_query-from>
      <Hsp_query-to>1958</Hsp_query-to>
      <Hsp_hit-from>11</Hsp_hit-from>
      <Hsp_hit-to>111</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>116</Hsp_align-len>
      <Hsp_qseq>SIMGKEKTHINIVVIGHVDSGKSTSTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITID---ISLW-------------KFETQKYYVTIIDAPGHRDF</Hsp_qseq>
      <Hsp_hseq>SLMDKVTNVRNMSVIAHVDHGKSTLTDSLVQRAGII----------SAAKAGEARFT-----DTRKDEQERGITIKSTAISLYSEMSDEDVKEIKQKTDGNSFLINLIDSPGHVDF</Hsp_hseq>
      <Hsp_midline>S+M K     N+ VI HVD GKST T  L+ + G I           AA+ G+  F      D  K E+ERGITI    ISL+             K +   + + +ID+PGH DF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YLR069C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:271630:273915:-1 gene:YLR069C transcript:YLR069C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEF1 description:Mitochondrial elongation factor involved in translational elongation [Source:SGD;Acc:S000004059]</Hit_def>
  <Hit_accession>YLR069C</Hit_accession>
  <Hit_len>761</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>1.92641e-06</Hsp_evalue>
      <Hsp_query-from>1656</Hsp_query-from>
      <Hsp_query-to>1958</Hsp_query-to>
      <Hsp_hit-from>61</Hsp_hit-from>
      <Hsp_hit-to>155</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>105</Hsp_align-len>
      <Hsp_qseq>PSIMGKEKTHINIVVIGHVDSGKSTSTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISL----WKFETQKYYVTIIDAPGHRDF</Hsp_qseq>
      <Hsp_hseq>PDDIGRCNKLRNIGISAHIDSGKTTFTERVLYYTKRI----------KAIHEVRGRDNVGAKMDSMDLEREKGITIQSAATYCSWDKEGKNYHFNLIDTPGHIDF</Hsp_hseq>
      <Hsp_midline>P  +G+     NI +  H+DSGK+T T  ++Y    I          +A    +G       +D +  ERE+GITI  +     W  E + Y+  +ID PGH DF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YJL102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:231301:233760:1 gene:YJL102W transcript:YJL102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEF2 description:Mitochondrial elongation factor involved in translational elongation [Source:SGD;Acc:S000003638]</Hit_def>
  <Hit_accession>YJL102W</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>3.36766e-06</Hsp_evalue>
      <Hsp_query-from>1689</Hsp_query-from>
      <Hsp_query-to>1958</Hsp_query-to>
      <Hsp_hit-from>43</Hsp_hit-from>
      <Hsp_hit-to>120</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>91</Hsp_align-len>
      <Hsp_qseq>NIVVIGHVDSGKSTSTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETQKYY-VTIIDAPGHRDF</Hsp_qseq>
      <Hsp_hseq>NIGIIAHIDAGKTTTTERMLYYAG---------ISKHIGDVDTGDT----ITDFLEQERSRGITIQSAAISFPWRNTFAINLIDTPGHIDF</Hsp_hseq>
      <Hsp_midline>NI +I H+D+GK+T+T  ++Y  G           K   ++  G      + D L+ ER RGITI  +   F  +  + + +ID PGH DF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>105</Statistics_hsp-len>
      <Statistics_eff-space>4255564372</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056604-RA transcript Note:&quot;Similar to TBC1D7 TBC1 domain family member 7 (Homo sapiens)&quot; offset:65 AED:0.05 eAED:0.05 QI:65|0.66|0.71|1|0.83|0.71|7|2267|229</Iteration_query-def>
  <Iteration_query-len>3022</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>2052685636</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0041057-RA transcript Note:&quot;Similar to Zbtb8a Zinc finger and BTB domain-containing protein 8A (Rattus norvegicus)&quot; offset:0 AED:0.39 eAED:1.00 QI:0|0|0|1|0|0.33|3|0|336</Iteration_query-def>
  <Iteration_query-len>1011</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YJL056C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:330431:333073:-1 gene:YJL056C transcript:YJL056C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZAP1 description:Zinc-regulated transcription factor; binds to zinc-responsive promoters to induce transcription of certain genes in presence of zinc, represses other genes in low zinc; regulates its own transcription; contains seven zinc-finger domains [Source:SGD;Acc:S000003592]</Hit_def>
  <Hit_accession>YJL056C</Hit_accession>
  <Hit_len>880</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>1.69558e-07</Hsp_evalue>
      <Hsp_query-from>742</Hsp_query-from>
      <Hsp_query-to>993</Hsp_query-to>
      <Hsp_hit-from>768</Hsp_hit-from>
      <Hsp_hit-to>848</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>FPCKHCPVRFTAKENLVRHQRTVHAGQKLKFCEACQRNFRDSTDLQRHRLSKHWWQGRDGTCPFCPERFRVSRELLKHIQHRHR</Hsp_qseq>
      <Hsp_hseq>YKCKTCKRCFSSEETLVQHTRT-HSGEKPYKCHICNKKFAISSSLKIH-IRTHTGE-KPLQCKICGKRFNESSNLSKHIKTHQK</Hsp_hseq>
      <Hsp_midline>+ CK C   F+++E LV+H RT H+G+K   C  C + F  S+ L+ H +  H  + +   C  C +RF  S  L KHI+   +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>573056549</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056607-RA transcript Note:&quot;Similar to Edn1 Endothelin-1 (Rattus norvegicus)&quot; offset:0 AED:0.58 eAED:0.58 QI:0|0|0|0.25|1|1|4|0|171</Iteration_query-def>
  <Iteration_query-len>516</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>83</Statistics_hsp-len>
      <Statistics_eff-space>210597763</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056608-RA transcript Note:&quot;Similar to Sgs4 Salivary glue protein Sgs-4 (Drosophila melanogaster)&quot; offset:0 AED:0.10 eAED:0.10 QI:0|0|0|1|1|0.66|3|0|398</Iteration_query-def>
  <Iteration_query-len>1197</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>92</Statistics_hsp-len>
      <Statistics_eff-space>708208169</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0004483-RA transcript Note:&quot;Similar to mapk15 Mitogen-activated protein kinase 15 (Xenopus laevis)&quot; offset:783 AED:0.24 eAED:0.25 QI:783|0.66|0.61|1|0.5|0.53|13|0|682</Iteration_query-def>
  <Iteration_query-len>2832</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>199.519</Hsp_bit-score>
      <Hsp_score>506</Hsp_score>
      <Hsp_evalue>3.54432e-57</Hsp_evalue>
      <Hsp_query-from>832</Hsp_query-from>
      <Hsp_query-to>1653</Hsp_query-to>
      <Hsp_hit-from>49</Hsp_hit-from>
      <Hsp_hit-to>322</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>124</Hsp_identity>
      <Hsp_positive>164</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>287</Hsp_align-len>
      <Hsp_qseq>KRLGKGRTFREIIFLQEFGDHPNIINLRNVLR---ADNDKDIYLVFDFMDTDLHAVIRKGN----ILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRD--EPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSVIPQPSKEDVLAIKS----EYGGSVLEKMGRQRQSLESXXXXXXXXXXXXXKRLLVFNPEKRLTAEEALGHPYVAQFHNPQTE</Hsp_qseq>
      <Hsp_hseq>KKLFVTRTIREIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIK-------PSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQE-----YTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIANLPMRPPLPWETVWSKTDLNPDMIDLLDK-MLQFNPDKRISAAEALRHPYLAMYHDPSDE</Hsp_hseq>
      <Hsp_midline>K+L   RT REI  L+ F +H NII++ + +R    D    +YLV + M+TDL  VI   N     L D H  Y TYQ+L+A K IHS  VIHRD K       PSN+LL+  C +K+CDFGLAR L    D  E     +TEYVATRWYRAPEI+L         YT  +D+WS GCI+ EM+ GK +FPG    +Q+  I+ V+  PS ED   IKS    EY  ++  +     +++ S     P     L K +L FNP+KR++A EAL HPY+A +H+P  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>194.126</Hsp_bit-score>
      <Hsp_score>492</Hsp_score>
      <Hsp_evalue>2.14759e-55</Hsp_evalue>
      <Hsp_query-from>832</Hsp_query-from>
      <Hsp_query-to>1653</Hsp_query-to>
      <Hsp_hit-from>49</Hsp_hit-from>
      <Hsp_hit-to>318</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>117</Hsp_identity>
      <Hsp_positive>167</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>284</Hsp_align-len>
      <Hsp_qseq>KRLGKGRTFREIIFLQEFGDHPNIINLRNVLRAD---NDKDIYLVFDFMDTDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPA-----LTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSVIPQP-SKEDVLAIKSEYGGSVLEKMGRQRQS-LESXXXXXXXXXXXXXKRLLVFNPEKRLTAEEALGHPYVAQFHNPQTE</Hsp_qseq>
      <Hsp_hseq>KPLFALRTLREIKILKHFK-HENIITIFNIQRPDSFENFNEVYIIQELMQTDLHRVI-STQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLK-------PSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTS-----AKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHSDNDLRCIESPRAREYIKSLPMYPAAPLEKMFPRVNPKGIDLLQRMLVFDPAKRITAKEALEHPYLQTYHDPNDE</Hsp_hseq>
      <Hsp_midline>K L   RT REI  L+ F  H NII + N+ R D   N  ++Y++ + M TDLH VI    +L D H  Y  YQ L+A K +H  NVIHRD K       PSN+L++  C +K+CDFGLAR + +   +  +P      +TEYVATRWYRAPE++L S      +Y++ +D+WS GCI+ E+ L + IFPG    +Q+  I  +I  P S  D+  I+S      ++ +     + LE + P   P  +DLL+R+LVF+P KR+TA+EAL HPY+  +H+P  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>186.808</Hsp_bit-score>
      <Hsp_score>473</Hsp_score>
      <Hsp_evalue>2.08689e-51</Hsp_evalue>
      <Hsp_query-from>826</Hsp_query-from>
      <Hsp_query-to>1653</Hsp_query-to>
      <Hsp_hit-from>60</Hsp_hit-from>
      <Hsp_hit-to>327</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>115</Hsp_identity>
      <Hsp_positive>164</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>281</Hsp_align-len>
      <Hsp_qseq>IKKRLGKGRTFREIIFLQEFGDHPNIINLRN---VLRADNDKD-IYLVFDFMDTDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSVIPQPSKEDVLAIKSEYGGSVLEKMGR-QRQSLESXXXXXXXXXXXXXKRLLVFNPEKRLTAEEALGHPYVAQFHNPQTE</Hsp_qseq>
      <Hsp_hseq>FSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLK-------PGNLLVNADCQLKICDFGLARGYSENPVE-NSQFLTEYVATRWYRAPEIMLSYQ-----GYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPYLSIWHDPADE</Hsp_hseq>
      <Hsp_midline>  K L   R+ RE+  L+ F  H NI  L +   V   D   + +YL  + M+ D+H +I+ G  L D H    TYQ+L   KYIHS +V+HRD K       P N+L++ +C +K+CDFGLAR   +   E     LTEYVATRWYRAPEI+L+        YTK +D+WS GCI+ E L GK IF G   +NQ+ +I+ V+  P  E +  I S+     + ++G   +    +L PNA   ALDLL+++L F+P+KR+T +EAL HPY++ +H+P  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>167.933</Hsp_bit-score>
      <Hsp_score>424</Hsp_score>
      <Hsp_evalue>2.21041e-45</Hsp_evalue>
      <Hsp_query-from>850</Hsp_query-from>
      <Hsp_query-to>1653</Hsp_query-to>
      <Hsp_hit-from>66</Hsp_hit-from>
      <Hsp_hit-to>311</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>104</Hsp_identity>
      <Hsp_positive>154</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>269</Hsp_align-len>
      <Hsp_qseq>RTFREIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDTDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSVIPQPSKEDVLAIKSEYGGSVLEKM-GRQRQSLESXXXXXXXXXXXXXKRLLVFNPEKRLTAEEALGHPYVAQFHNPQTE</Hsp_qseq>
      <Hsp_hseq>RTYRELKLLKHLR-HENLICLQDIFLSPL-EDIYFVTELQGTDLHRLLQTRPLEKQFVQ-YFLYQILRGLKYVHSAGVIHRDLK-------PSNILINENCDLKICDFGLARI--------QDPQMTGYVSTRYYRAPEIMLTWQK-----YDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENTLKFVTSLPHRDPIPFSERFKTVEPDAVDLLEKMLVFDPKKRITAADALAHPYSAPYHDPTDE</Hsp_hseq>
      <Hsp_midline>RT+RE+  L+    H N+I L+++  +   +DIY V +   TDLH +++   + K   + Y  YQ+L+  KY+HS  VIHRD K       PSN+L++  C +K+CDFGLAR          DP +T YV+TR+YRAPEI+L   +     Y   VD+WS GCI  EM+ GK +FPG   ++Q   I  ++  P K+ +  I SE     +  +  R             P+A+DLL+++LVF+P+KR+TA +AL HPY A +H+P  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>163.31</Hsp_bit-score>
      <Hsp_score>412</Hsp_score>
      <Hsp_evalue>6.96841e-44</Hsp_evalue>
      <Hsp_query-from>835</Hsp_query-from>
      <Hsp_query-to>1773</Hsp_query-to>
      <Hsp_hit-from>63</Hsp_hit-from>
      <Hsp_hit-to>365</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>111</Hsp_identity>
      <Hsp_positive>177</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>318</Hsp_align-len>
      <Hsp_qseq>RLGKGRTFREIIFLQEFGDHPNIINL--RNVLRADND--KDIYLVFDFMDTDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSVIPQPSKEDVLAIKSEYGGSVLEKMGRQ-RQSLESXXXXXXXXXXXXXKRLLVFNPEKRLTAEEALGHPYVAQFHNPQTELAXXXXXXXXXXXXTRLSVAEYRNKLYELILERKMDVRKH</Hsp_qseq>
      <Hsp_hseq>KLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLYEELMECDLSQIIRSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLK-------PKNLLVNSDCQLKICNFGLSCSYSE-NHKVNDGFIKGYITSIWYKAPEILLNYQE---C--TKAVDIWSTGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIPGRSFESILPGANPEALELLKKMLEFDPKKRITVEDALEHPYLSMWHDIDEEFSCQKTFRFEFEHIE--SMAELGNEVIKEVFDFRKVVRKH</Hsp_hseq>
      <Hsp_midline>+L   RT RE+  L+    HPNI+ L   +++   N     +YL  + M+ DL  +IR    L+D H     YQ+L A KYIHS NV+H D K       P N+L++ +C +K+C+FGL+ S  +   +  D  +  Y+ + WY+APEILL       C  TK VD+WS GCI+ E+L  K +F G   ++ +  I+ ++  P +E +  I S+   + + + G    +S ES+LP A P AL+LLK++L F+P+KR+T E+AL HPY++ +H+   E +         +     S+AE  N++ + + + +  VRKH</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>144.436</Hsp_bit-score>
      <Hsp_score>363</Hsp_score>
      <Hsp_evalue>9.43689e-38</Hsp_evalue>
      <Hsp_query-from>850</Hsp_query-from>
      <Hsp_query-to>1653</Hsp_query-to>
      <Hsp_hit-from>83</Hsp_hit-from>
      <Hsp_hit-to>346</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>95</Hsp_identity>
      <Hsp_positive>146</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>276</Hsp_align-len>
      <Hsp_qseq>RTFREIIFLQEFGDHPNIINLRN--VLRADNDKDIYLVFDFMDTDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDE---PGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSVIPQPSKEDVL---AIKSEYGGSVLEKMGRQRQSLESXXXXXXXXXXXXXKRLLVFNPEKRLTAEEALGHPYVAQFHNPQTE</Hsp_qseq>
      <Hsp_hseq>RAIRELKFMNFFKGHKNIVNLIDLEIVTSSPYDGLYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLK-------PGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQ-----PYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDKDILIKFGTIKAWNLGKNSNNPVYKKIPWSNIFPFASHEAINLIESLLHWDSTHRLNVEQAISHPFLNEVRKPDDE</Hsp_hseq>
      <Hsp_midline>R  RE+ F+  F  H NI+NL +  ++ +     +Y   + +D DL  VI     L + H  Y  YQ+L   KYIHS +VIHRD K       P N+L      +K+CDFGLAR +     +      P +T YVATRWYRAPE+LL++       Y+K VD+W+VGCI+ E    K +F G  +++QI  I+ V+  P K+ ++    IK+   G        ++    ++ P A   A++L++ LL ++   RL  E+A+ HP++ +   P  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>127.487</Hsp_bit-score>
      <Hsp_score>319</Hsp_score>
      <Hsp_evalue>8.48013e-33</Hsp_evalue>
      <Hsp_query-from>856</Hsp_query-from>
      <Hsp_query-to>1638</Hsp_query-to>
      <Hsp_hit-from>51</Hsp_hit-from>
      <Hsp_hit-to>301</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>89</Hsp_identity>
      <Hsp_positive>144</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>273</Hsp_align-len>
      <Hsp_qseq>FREIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDTDLHAVIRK---GNILKDVH---KAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPA--LTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSVIPQPSKEDVLAIKS--EYGGSVLEKMGRQ-RQSLESXXXX-XXXXXXXXXKRLLVFNPEKRLTAEEALGHPYVAQFH</Hsp_qseq>
      <Hsp_hseq>IREISLMKEL-KHENIVRLYDVIHTENK--LTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLK-------PQNLLINKRGQLKLGDFGLARAF-------GIPVNTFSSEVVTLWYRAPDVLMGSRT-----YSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPKYNPNIQQRPPRDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWFAEYY</Hsp_hseq>
      <Hsp_midline> REI  ++E   H NI+ L +V+  +N   + LVF+FMD DL   +     GN  + +      Y  +QLL+   + H   ++HRD K       P N+L++    +KL DFGLAR+        G P    +  V T WYRAP++L+ S       Y+  +D+WS GCI+ EM+ GK +FPGT+   Q++ I  ++  P++    ++    +Y  ++ ++  R  RQ L+         N +D L  LL  NP+ RL+A++AL HP+ A+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>124.02</Hsp_bit-score>
      <Hsp_score>310</Hsp_score>
      <Hsp_evalue>1.15326e-31</Hsp_evalue>
      <Hsp_query-from>856</Hsp_query-from>
      <Hsp_query-to>1623</Hsp_query-to>
      <Hsp_hit-from>56</Hsp_hit-from>
      <Hsp_hit-to>294</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>94</Hsp_identity>
      <Hsp_positive>145</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>265</Hsp_align-len>
      <Hsp_qseq>FREIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDTDL----HAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDP--ALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSVIPQPSKE---DVLAIKSEYGGSVLEKMGRQRQSLESXXXXXXXXXXXXXKRLLVFNPEKRLTAEEALGHPY</Hsp_qseq>
      <Hsp_hseq>IREISLLKELKDD-NIVRLYDIVHSDAHK-LYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMM-QLCKGIAYCHSHRILHRDLK-------PQNLLINKDGNLKLGDFGLARAF-------GVPLRAYTHEIVTLWYRAPEVLLGGKQ-----YSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIVYL-PDFKPSFPQ---WRRKDLSQVVPSLDPRGIDLLDKLLAYDPINRISARRAAIHPY</Hsp_hseq>
      <Hsp_midline> REI  L+E  D  NI+ L +++ +D  K +YLVF+F+D DL      + +   +  D+ K ++  QL K   Y HS  ++HRD K       P N+L++ +  +KL DFGLAR+        G P  A T  + T WYRAPE+LL   +     Y+ GVD WS+GCI  EM   K IF G S ++QI +I  V+  P++    D++ +  ++  S  +    +R+ L  ++P+  P  +DLL +LL ++P  R++A  A  HPY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>122.865</Hsp_bit-score>
      <Hsp_score>307</Hsp_score>
      <Hsp_evalue>1.29726e-30</Hsp_evalue>
      <Hsp_query-from>859</Hsp_query-from>
      <Hsp_query-to>1656</Hsp_query-to>
      <Hsp_hit-from>79</Hsp_hit-from>
      <Hsp_hit-to>337</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>92</Hsp_identity>
      <Hsp_positive>142</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>278</Hsp_align-len>
      <Hsp_qseq>REIIFLQEFGDHPNIINLRNVLR--ADNDKDIY--LVFDFMDTDLHAVIRK--GNILKD--VHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFV-KLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSVIPQPSKEDVLAIKSEYGGSVLEK---MGRQRQSLESXXXXXXXXXXXXXKRLLVFNPEKRLTAEEALGHPYVAQFHNPQTEL</Hsp_qseq>
      <Hsp_hseq>RELQILR-IADHPNIVKLQYFFTHLSPQDNKVYQHLAMECLPETLQIEINRYVTNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIK-------PSNVLVDPETGVLKICDFGSAKKL-----EHNQPSIS-YICSRFYRAPELIIGC-----TQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLREIAKLLGPPDKRFIFFSNPAYDGPLFSKPLFSGSSQQRFEKYFGHSGPDGIDLLMKILVYEPQQRLSPRRILAHQFFNELRNDDTFL</Hsp_hseq>
      <Hsp_midline>RE+  L+   DHPNI+ L+      +  D  +Y  L  + +   L   I +   N L+    H    TYQ+ +   Y+H   V HRD K       PSNVL+D E  V K+CDFG A+ L     E   P+++ Y+ +R+YRAPE+++        +YT  +D+W +GC++GEML+GKAIF G   L Q+  I  ++  P K  +      Y G +  K    G  +Q  E    ++ P+ +DLL ++LV+ P++RL+    L H +  +  N  T L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>120.168</Hsp_bit-score>
      <Hsp_score>300</Hsp_score>
      <Hsp_evalue>8.81363e-30</Hsp_evalue>
      <Hsp_query-from>817</Hsp_query-from>
      <Hsp_query-to>1623</Hsp_query-to>
      <Hsp_hit-from>64</Hsp_hit-from>
      <Hsp_hit-to>321</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>83</Hsp_identity>
      <Hsp_positive>144</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>278</Hsp_align-len>
      <Hsp_qseq>KYDIKKRLGKGRTFREIIFLQEFGDHPNIINLRNVLRA-DNDKDIYL--VFDFMDTDLHAVIR----KGNILKDVHKAYITYQLLKATKYIHS-GNVIHRDQKAGPLLPLPSNVLLDGECF-VKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSVIPQPSKEDVLAIKSEYGGSVLEKMGRQRQSLESXXXXXXXXXXXXXKRLLVFNPEKRLTAEEALGHPY</Hsp_qseq>
      <Hsp_hseq>KVAIKKVLQDKRFKNRELEIMKMLSHINIIDLKYFFYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIK-------PQNLLVDPETWSLKLCDFGSAKQLK-----PTEPNVS-YICSRYYRAPELIFGA-----TNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILGTPSKQEICSMNPNYMEHKFPQI--KPIPLSRVFKKEDDQTVEFLADVLKYDPLERFNALQCLCSPY</Hsp_hseq>
      <Hsp_midline>K  IKK L   R     + + +   H NII+L+      D+  +IYL  + ++M   L+  +R    +   +  +   Y  +QL K+  Y+H   NV HRD K       P N+L+D E + +KLCDFG A+ LK     P +P ++ Y+ +R+YRAPE++  +       YT  +D+WS GC++ E+LLG+ +FPG S ++Q+  I+ ++  PSK+++ ++   Y      ++  +   L  +        ++ L  +L ++P +R  A + L  PY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>121.324</Hsp_bit-score>
      <Hsp_score>303</Hsp_score>
      <Hsp_evalue>3.72328e-29</Hsp_evalue>
      <Hsp_query-from>853</Hsp_query-from>
      <Hsp_query-to>1434</Hsp_query-to>
      <Hsp_hit-from>227</Hsp_hit-from>
      <Hsp_hit-to>401</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>195</Hsp_align-len>
      <Hsp_qseq>TFREIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDTDLHAVIRKGNI-LKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSVIPQPS</Hsp_qseq>
      <Hsp_hseq>SIREIKLLQSF-DHPNVSTIKEIM-VESQKTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKG-------SNILIDNQGNLKITDFGLARKMNSRAD------YTNRVITLWYRPPELLLGT-----TNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTPT</Hsp_hseq>
      <Hsp_midline>+ REI  LQ F DHPN+  ++ ++  ++ K +Y++F++ D DL  ++    + +      ++  QLL   +Y+H   ++HRD K        SN+L+D +  +K+ DFGLAR +    D       T  V T WYR PE+LL +       Y   VDMW  GC++ E+    AIF G++ L QIE I  ++  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>114.005</Hsp_bit-score>
      <Hsp_score>284</Hsp_score>
      <Hsp_evalue>3.81797e-28</Hsp_evalue>
      <Hsp_query-from>859</Hsp_query-from>
      <Hsp_query-to>1644</Hsp_query-to>
      <Hsp_hit-from>53</Hsp_hit-from>
      <Hsp_hit-to>296</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>86</Hsp_identity>
      <Hsp_positive>133</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>266</Hsp_align-len>
      <Hsp_qseq>REIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDTDLHAVIRKGNIL---KDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSVIPQPSKEDVLAIKSEYGGSVLEKM-GRQRQSLESXXXXXXXXXXXXXKRLLVFNPEKRLTAEEALGHPYVAQFHNP</Hsp_qseq>
      <Hsp_hseq>REVKYLQEM-QHPNVIELIDIFMAYDNLN--LVLEFLPTDLEVVIKDKSILFTPADI-KAWML-MTLRGVYHCHRNFILHRDLK-------PNNLLFSPDGQIKVADFGLARAIPAPHE-----ILTSNVVTRWYRAPELLFGAKH-----YTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDRDWPEVSSFMTYNKLQIYPPPSRDELRKRFIAASEYALDFMCGMLTMNPQKRWTAVQCLESDYFKELPPP</Hsp_hseq>
      <Hsp_midline>RE+ +LQE   HPN+I L ++  A ++ +  LV +F+ TDL  VI+  +IL    D+ KA++    L+   + H   ++HRD K       P+N+L   +  +K+ DFGLAR++    +      LT  V TRWYRAPE+L  +       YT  +D+WSVG I  E++L     PG + ++Q+E     +  P+  D   + S    + L+      R  L      A   ALD +  +L  NP+KR TA + L   Y  +   P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>115.546</Hsp_bit-score>
      <Hsp_score>288</Hsp_score>
      <Hsp_evalue>6.58191e-27</Hsp_evalue>
      <Hsp_query-from>859</Hsp_query-from>
      <Hsp_query-to>1632</Hsp_query-to>
      <Hsp_hit-from>106</Hsp_hit-from>
      <Hsp_hit-to>368</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>86</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>277</Hsp_align-len>
      <Hsp_qseq>REIIFLQEFGDHPNIINL-----------RNVLRADNDKDIYLVFDFMDTDLHAVIRKGNI-LKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLAR-------SLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSVIPQPSKEDVLAIKSEYGGSVLEKMGRQRQSLESXXXXXXXXXXXXXKRLLVFNPEKRLTAEEALGHPYVAQ</Hsp_qseq>
      <Hsp_hseq>REITILKRL-NHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKT-------ANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDK-----QYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTEED-WAVARYLPGAELTTTNYKPTLRERFGKYLSETGLDFLGQLLALDPYKRLTAMSAKHHPWFKE</Hsp_hseq>
      <Hsp_midline>REI  L+   +H NII L            N   ++  K  Y++  +M  DL  V+    I L+      +  Q+L+   YIH    +HRD K        +N+L+D    +KL DFGLAR       +LK           T  V TRWYRAPE++L        +YT  VD+W VGC+  E    K I  G + ++Q   I  ++  P++ED  A+     G+ L     +    E          LD L +LL  +P KRLTA  A  HP+  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YDL079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:312951:314748:-1 gene:YDL079C transcript:YDL079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRK1 description:Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication [Source:SGD;Acc:S000002237]</Hit_def>
  <Hit_accession>YDL079C</Hit_accession>
  <Hit_len>501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>112.079</Hsp_bit-score>
      <Hsp_score>279</Hsp_score>
      <Hsp_evalue>3.18435e-26</Hsp_evalue>
      <Hsp_query-from>892</Hsp_query-from>
      <Hsp_query-to>1482</Hsp_query-to>
      <Hsp_hit-from>214</Hsp_hit-from>
      <Hsp_hit-to>401</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>206</Hsp_align-len>
      <Hsp_qseq>HPNIINLRNVL-RADNDKDIYL--VFDFMDTDLHAVIRKGNILK----DVHKAYITYQLLKATKYIHSG-NVIHRDQKAGPLLPLPSNVLLDGECF-VKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSVIPQPSKEDVLAIKSEYGGSVL</Hsp_qseq>
      <Hsp_hseq>HPNTVGLQYYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNVPRICHRDIK-------PQNLLVDPTTFSFKICDFGSAKCLK-----PDQPNVS-YICSRYYRAPELMFGA-----TNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKIMGIPTKDEISGMNPNYEDHVF</Hsp_hseq>
      <Hsp_midline>HPN + L+      D + ++YL  V D+M   L+  +R    LK     V   +  YQL KA  Y+H+   + HRD K       P N+L+D   F  K+CDFG A+ LK     P  P ++ Y+ +R+YRAPE++  +       Y+  VD+WS  C++ E+LLGK +F G S ++Q+  I+ ++  P+K+++  +   Y   V </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>103.99</Hsp_bit-score>
      <Hsp_score>258</Hsp_score>
      <Hsp_evalue>2.19522e-23</Hsp_evalue>
      <Hsp_query-from>859</Hsp_query-from>
      <Hsp_query-to>1437</Hsp_query-to>
      <Hsp_hit-from>113</Hsp_hit-from>
      <Hsp_hit-to>306</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>205</Hsp_align-len>
      <Hsp_qseq>REIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDTDLHAVI--RKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECF----------VKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSVIPQPSK</Hsp_qseq>
      <Hsp_hseq>REIKFILAIPANDHLIQIFEVFIDSENYQLHIVMECMEQNLYQMMKHRRRRVFSIPSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHV-----ENKNP-YTAYVSTRWYRSPEILLRS-----GYYSKPLDIWAFGCVAVEVTVFRALFPGANEIDQIWKILEVLGTPIK</Hsp_hseq>
      <Hsp_midline>REI F+     + ++I +  V     +  +++V + M+ +L+ ++  R+  +        I  Q+L   K+IH  N  HRD K   +L  PS    + E            +KL DFGLAR +     E  +P  T YV+TRWYR+PEILL S       Y+K +D+W+ GC+  E+ + +A+FPG + ++QI +I+ V+  P K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.1301</Hsp_bit-score>
      <Hsp_score>235</Hsp_score>
      <Hsp_evalue>2.42211e-21</Hsp_evalue>
      <Hsp_query-from>892</Hsp_query-from>
      <Hsp_query-to>1446</Hsp_query-to>
      <Hsp_hit-from>95</Hsp_hit-from>
      <Hsp_hit-to>273</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>196</Hsp_align-len>
      <Hsp_qseq>HPNIINLRNVLRAD-NDKD---IY---LVFDF----MDTDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSVIPQPSKEDV</Hsp_qseq>
      <Hsp_hseq>HPNLVTLEFFFESHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGI------AKVCDFGSAQRLDD------NTELKTYFCSRFYRAPELLLNSKD-----YTTQIDIWSLGCIIGEMIKGQPLFKGDSANSQLEEIAKLLGRFPKSSI</Hsp_hseq>
      <Hsp_midline>HPN++ L     +    KD   +Y    V ++    + +++H     G+ +   H    T+Q+L+A   +HS ++ H D K   +L +PS+ +       K+CDFG A+ L        +  L  Y  +R+YRAPE+LL S       YT  +D+WS+GCI+GEM+ G+ +F G S  +Q+E I  ++ +  K  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>92.8189</Hsp_bit-score>
      <Hsp_score>229</Hsp_score>
      <Hsp_evalue>5.21379e-20</Hsp_evalue>
      <Hsp_query-from>940</Hsp_query-from>
      <Hsp_query-to>1653</Hsp_query-to>
      <Hsp_hit-from>230</Hsp_hit-from>
      <Hsp_hit-to>472</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>124</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>259</Hsp_align-len>
      <Hsp_qseq>KDIYLVFDFMDTDLHAVIR-----KGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDE--PGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTST-----------LNQIERIMSVIPQPSKEDVLAIKSEYGGSVLEKMGRQRQSLESXXXXX---XXXXXXXXKRLLVFNPEKRLTAEEALGHPYVAQFHNPQTE</Hsp_qseq>
      <Hsp_hseq>KCVHMVYEYAEHDLLQIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLK-------PANIMVTIDGCVKIGDLGLARKFHNMLQTLYTGDKV----VVTIWYRAPELLLGARH-----YTPAVDLWSVGCIFAELIGLQPIFKGEEAKLDSKKTVPFQVNQLQRILEVLGTPDQKIWPYLEKYPEYDQITKFPKYRDNLATWYHSAGGRDKHALSLLYHLLNYDPIKRIDAFNALEHKYFTESDIPVSE</Hsp_hseq>
      <Hsp_midline>K +++V+++ + DL  +I      +  ++       I +QLL    Y+H   V+HRD K       P+N+++  +  VK+ D GLAR    +      GD      V T WYRAPE+LL +       YT  VD+WSVGCI  E++  + IF G              +NQ++RI+ V+  P ++    ++       + K  + R +L +   +A     +AL LL  LL ++P KR+ A  AL H Y  +   P +E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>92.8189</Hsp_bit-score>
      <Hsp_score>229</Hsp_score>
      <Hsp_evalue>1.1723e-19</Hsp_evalue>
      <Hsp_query-from>874</Hsp_query-from>
      <Hsp_query-to>1419</Hsp_query-to>
      <Hsp_hit-from>231</Hsp_hit-from>
      <Hsp_hit-to>404</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>189</Hsp_align-len>
      <Hsp_qseq>LQEFGDHPNIINLRNVLRADNDKDIYLVFDFM-DTDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPAL------TEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSV</Hsp_qseq>
      <Hsp_hseq>LQKLNNSPSVVRLFSTFQ--DESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIK-------PENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRC------DIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKV</Hsp_hseq>
      <Hsp_midline>LQ+  + P+++ L +  +  ++  +Y + ++  + D  ++++K   L +    Y   Q++ A  Y+HS  +IHRD K       P N+LLDGE  +KL DFG A+ L    +    P          +V T  Y +PE+L  S     C      D+W+ GCI+ +M+ GK  F  T+     +++M V</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.8113</Hsp_bit-score>
      <Hsp_score>216</Hsp_score>
      <Hsp_evalue>5.55203e-18</Hsp_evalue>
      <Hsp_query-from>889</Hsp_query-from>
      <Hsp_query-to>1623</Hsp_query-to>
      <Hsp_hit-from>1236</Hsp_hit-from>
      <Hsp_hit-to>1439</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>51</Hsp_gaps>
      <Hsp_align-len>250</Hsp_align-len>
      <Hsp_qseq>DHPNIINLRNVLRADNDKDIYLVF-DFM-DTDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPG---TSTLNQIERIMSVIPQPSKEDVLAIKSEYGGSVLEKMGRQRQSLESXXXXXXXXXXXXXKRLLVFNPEKRLTAEEALGHPY</Hsp_qseq>
      <Hsp_hseq>DHLNIVQY---LGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKAD-------NLLLDQDGICKISDFGISRKSKDIYSN-SDMTMR---GTVFWMAPEMV-----DTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIP--EDTLPLISQIGRNFLDA-------------------------CFEINPEKRPTANELLSHPF</Hsp_hseq>
      <Hsp_midline>DH NI+     L  +N  +IY +F +++    + ++IR      +    ++T Q+LK   Y+HS  ++HRD KA        N+LLD +   K+ DFG++R  K I     D  +     T ++ APE++          Y+  VD+WS+GCIV EM  GK  +      + + +I +  S  P P  ED L + S+ G + L+                              NPEKR TA E L HP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.8853</Hsp_bit-score>
      <Hsp_score>211</Hsp_score>
      <Hsp_evalue>1.34723e-17</Hsp_evalue>
      <Hsp_query-from>952</Hsp_query-from>
      <Hsp_query-to>1431</Hsp_query-to>
      <Hsp_hit-from>447</Hsp_hit-from>
      <Hsp_hit-to>589</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>164</Hsp_align-len>
      <Hsp_qseq>LVFDFMDTDLHAVIRKGNI--LKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDG--ECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSVIPQP</Hsp_qseq>
      <Hsp_hseq>LVFELLSNNLYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLK-------PENILLCAPDKPELKIIDFG--SSCEEAR------TVYTYIQSRFYRAPEIILGIP------YSTSIDMWSLGCIVAELFLGIPIFPGASEYNQLTRIIDTLGYP</Hsp_hseq>
      <Hsp_midline>LVF+ +  +L+ ++++     L        T Q+L +   +    +IH D K       P N+LL    +  +K+ DFG   S ++ R       +  Y+ +R+YRAPEI+L  P      Y+  +DMWS+GCIV E+ LG  IFPG S  NQ+ RI+  +  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YIL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:287790:288908:-1 gene:YIL035C transcript:YIL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA1 description:Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000001297]</Hit_def>
  <Hit_accession>YIL035C</Hit_accession>
  <Hit_len>372</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.9593</Hsp_bit-score>
      <Hsp_score>206</Hsp_score>
      <Hsp_evalue>1.42957e-17</Hsp_evalue>
      <Hsp_query-from>850</Hsp_query-from>
      <Hsp_query-to>1629</Hsp_query-to>
      <Hsp_hit-from>116</Hsp_hit-from>
      <Hsp_hit-to>364</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>132</Hsp_positive>
      <Hsp_gaps>43</Hsp_gaps>
      <Hsp_align-len>276</Hsp_align-len>
      <Hsp_qseq>RTFREIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMD-TDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGEC-FVKLCDFGLARSLKQIRDEPGDPALTEY---VATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKA-IFPGTSTLNQIERIMSVIPQPSKEDVLAIKSEYGGSVLEKMGRQRQSLE----------SXXXXXXXXXXXXXKRLLVFNPEKRLTAEEALGHPYVA</Hsp_qseq>
      <Hsp_hseq>KFIRPYIFDQPHNGHANIIHLFDIIKDPISKTPALVFEYVDNVDFRILYPK---LTDLEIRFYMFELLKALDYCHSMGIMHRDVK-------PHNVMIDHKNKKLRLIDWGLAEFYH---------VNMEYNVRVASRFFKGPELLVDYR-----MYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLL---KYEITLPREFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWFA</Hsp_hseq>
      <Hsp_midline>+  R  IF Q    H NII+L ++++    K   LVF+++D  D   +  K   L D+   +  ++LLKA  Y HS  ++HRD K       P NV++D +   ++L D+GLA                EY   VA+R+++ PE+L+         Y   +D+WS G ++  M+  +   F GTS  +Q+ +I+ V+     E  L    +Y  ++  +     Q +           +   +     +DL+  LL ++ ++RLTA+EA+GHP+ A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.6481</Hsp_bit-score>
      <Hsp_score>200</Hsp_score>
      <Hsp_evalue>8.04676e-17</Hsp_evalue>
      <Hsp_query-from>889</Hsp_query-from>
      <Hsp_query-to>1464</Hsp_query-to>
      <Hsp_hit-from>126</Hsp_hit-from>
      <Hsp_hit-to>298</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>196</Hsp_align-len>
      <Hsp_qseq>DHPNIINLRNVLRADNDKDIYLVFDFMDT-DLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMS---VIPQPSKEDVLAIKSE</Hsp_qseq>
      <Hsp_hseq>EHPFLIRMWGTFQ--DARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLK-------PENILLDRNGHIKITDFGFAKEVQTVT--------WTLCGTPDYIAPEVITTKP------YNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSK</Hsp_hseq>
      <Hsp_midline>+HP +I +    +  + ++I++V D+++  +L +++RK     +    +   +++ A +Y+H+ N+I+RD K       P N+LLD    +K+ DFG A+ ++ +              T  Y APE++   P      Y K VD WS+G ++ EML G   F  T+ +   E+I+    V P     DV+ + S+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.2629</Hsp_bit-score>
      <Hsp_score>199</Hsp_score>
      <Hsp_evalue>3.71903e-16</Hsp_evalue>
      <Hsp_query-from>892</Hsp_query-from>
      <Hsp_query-to>1419</Hsp_query-to>
      <Hsp_hit-from>72</Hsp_hit-from>
      <Hsp_hit-to>245</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>189</Hsp_align-len>
      <Hsp_qseq>HPNIINLRNVLRADNDKDIYLVFDFM-DTDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSL---------KQIRDEPG---DPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSV</Hsp_qseq>
      <Hsp_hseq>HAGIIKLYYTFH--DEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLK-------PENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQ----CGY--GSDIWALGCMIYQFVQGQPPFRGENELKTFEKIVAL</Hsp_hseq>
      <Hsp_midline>H  II L       +++++Y V DF    +L +++ K     D+   + T QL+ A ++IHS  +IHRD K       P NVLLD +  + + DFG A ++         K   D  G   +     +V T  Y +PE+LL +     C Y  G D+W++GC++ + + G+  F G + L   E+I+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.337</Hsp_bit-score>
      <Hsp_score>194</Hsp_score>
      <Hsp_evalue>5.4723e-16</Hsp_evalue>
      <Hsp_query-from>892</Hsp_query-from>
      <Hsp_query-to>1446</Hsp_query-to>
      <Hsp_hit-from>144</Hsp_hit-from>
      <Hsp_hit-to>309</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>190</Hsp_align-len>
      <Hsp_qseq>HPNIINLRNVLRADNDKDIYLVFDFMDT-DLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALT-EYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSV---IPQPSKEDV</Hsp_qseq>
      <Hsp_hseq>HPFIIRMWGTFQ--DAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLK-------PENILLDKNGHIKITDFGFAKYV---------PDVTYTLCGTPDYIAPEVVSTKP------YNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDV</Hsp_hseq>
      <Hsp_midline>HP II +    +  + + I+++ D+++  +L +++RK     +    +   ++  A +Y+HS ++I+RD K       P N+LLD    +K+ DFG A+ +         P +T     T  Y APE++   P      Y K +D WS G ++ EML G   F  ++T+   E+I++     P    EDV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YOR061W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:441534:442553:1 gene:YOR061W transcript:YOR061W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA2 description:Alpha&apos; catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000005587]</Hit_def>
  <Hit_accession>YOR061W</Hit_accession>
  <Hit_len>339</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.7962</Hsp_bit-score>
      <Hsp_score>190</Hsp_score>
      <Hsp_evalue>8.76175e-16</Hsp_evalue>
      <Hsp_query-from>850</Hsp_query-from>
      <Hsp_query-to>1623</Hsp_query-to>
      <Hsp_hit-from>88</Hsp_hit-from>
      <Hsp_hit-to>333</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>136</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>272</Hsp_align-len>
      <Hsp_qseq>RTFREIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDTDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLD-GECFVKLCDFGLARSLKQIRDEPGDPALTEY---VATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKA-IFPGTSTLNQIERIMSVIPQPSKEDVLAIKSEYG-------GSVLEKMGRQRQS--LESXXXXXXXXXXXXXKRLLVFNPEKRLTAEEALGHPY</Hsp_qseq>
      <Hsp_hseq>KIYRELKILTNLTGGPNVVGLYDIVQDADSKIPALIFEEIKNVDFRTLYPTFKLPDIQ--YYFTQLLIALDYCHSMGIMHRDVK-------PQNVMIDPTERKLRLIDWGLAEFY-----HPG----VDYNVRVASRYHKGPELLVN-----LNQYDYSLDLWSVGCMLAAIVFKKEPFFKGSSNPDQLVKIATVL---GTKELLGYLGKYGLHLPSEYDNIMRDFTKKSWTHFITSETKLAVPEVVDLIDNLLRYDHQERLTAKEAMDHKF</Hsp_hseq>
      <Hsp_midline>+ +RE+  L      PN++ L ++++  + K   L+F+ +       +     L D+   Y   QLL A  Y HS  ++HRD K       P NV++D  E  ++L D+GLA         PG     +Y   VA+R+++ PE+L+      + +Y   +D+WSVGC++  ++  K   F G+S  +Q+ +I +V+     +++L    +YG        +++    ++  +  + S    A P  +DL+  LL ++ ++RLTA+EA+ H +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.7962</Hsp_bit-score>
      <Hsp_score>190</Hsp_score>
      <Hsp_evalue>1.81732e-15</Hsp_evalue>
      <Hsp_query-from>892</Hsp_query-from>
      <Hsp_query-to>1416</Hsp_query-to>
      <Hsp_hit-from>145</Hsp_hit-from>
      <Hsp_hit-to>297</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>176</Hsp_align-len>
      <Hsp_qseq>HPNIINLRNVLRADNDKDIYLVFDFMDT-DLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMS</Hsp_qseq>
      <Hsp_hseq>HPFIIRMWGTFQ--DSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLK-------PENILLDKNGHIKITDFGFAKYVPDVT--------YTLCGTPDYIAPEVVSTKP------YNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILN</Hsp_hseq>
      <Hsp_midline>HP II +    +  + + +++V D+++  +L +++RK     +    +   ++  A +Y+HS ++I+RD K       P N+LLD    +K+ DFG A+ +  +              T  Y APE++   P      Y K VD WS G ++ EML G   F  ++T+   E I++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.1814</Hsp_bit-score>
      <Hsp_score>191</Hsp_score>
      <Hsp_evalue>3.89271e-15</Hsp_evalue>
      <Hsp_query-from>808</Hsp_query-from>
      <Hsp_query-to>1374</Hsp_query-to>
      <Hsp_hit-from>448</Hsp_hit-from>
      <Hsp_hit-to>612</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>191</Hsp_align-len>
      <Hsp_qseq>ILLKYDIKKRLGKGRTFREIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDTD--LHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIF</Hsp_qseq>
      <Hsp_hseq>IVKKNEIAHTIGE----RNILVTTASKSSPFIVGLKFSFQTPTD--LYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIA-ELVLALEHLHDNDIVYRDLK-------PENILLDANGNIALCDFGLSKA--DLKDR-----TNTFCGTTEYLAPELLLDE-----TGYTKMVDFWSLGVLIFEMCCGWSPF</Hsp_hseq>
      <Hsp_midline>I+ K +I   +G+    R I+        P I+ L+   +   D  +YLV D+M        + ++G   +D  K YI  +L+ A +++H  ++++RD K       P N+LLD    + LCDFGL+++   ++D         +  T  Y APE+LL         YTK VD WS+G ++ EM  G + F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.0258</Hsp_bit-score>
      <Hsp_score>188</Hsp_score>
      <Hsp_evalue>4.44781e-15</Hsp_evalue>
      <Hsp_query-from>844</Hsp_query-from>
      <Hsp_query-to>1623</Hsp_query-to>
      <Hsp_hit-from>241</Hsp_hit-from>
      <Hsp_hit-to>479</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>84</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>57</Hsp_gaps>
      <Hsp_align-len>278</Hsp_align-len>
      <Hsp_qseq>KGRTFREIIFLQEFGDHPNIINLRNVLRADNDKD---IYLVFDFMDTD--LHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLL------PLPSNVLL------DGECFVKLCDFGLARSLKQIRDEPGDPALTEYVA-TRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSVIPQPSKEDVLAIKSEYGGSVLEKMGRQRQSLESXXXXXXXXXXXXXKRLLVFNPEKRLTAEEALGHPY</Hsp_qseq>
      <Hsp_hseq>KNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFK-QLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKF-------TGEMQFTNTLCGTPSYVAPEVLTKKG------YTSKVDLWSAGVILYVCLCG---FPPFSD--------QLGPPSLKEQILQAKYAFYSPYWDKIDDSVLHLIS--------------NLLVLNPDERYNIDEALNHPW</Hsp_hseq>
      <Hsp_midline>K + FRE   +     HPNI+NL +       K     YLV + +D       ++RK  + +D  KA    QLL   KY+H  N+IHRD K   +L        PS V L      + +  VK+ DFGLA+         G+   T  +  T  Y APE+L          YT  VD+WS G I+   L G   FP  S          + P   KE +L  K  +     +K+      L S               LLV NP++R   +EAL HP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.8702</Hsp_bit-score>
      <Hsp_score>185</Hsp_score>
      <Hsp_evalue>1.71671e-14</Hsp_evalue>
      <Hsp_query-from>784</Hsp_query-from>
      <Hsp_query-to>1374</Hsp_query-to>
      <Hsp_hit-from>578</Hsp_hit-from>
      <Hsp_hit-to>768</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>211</Hsp_align-len>
      <Hsp_qseq>MNTDIDS-HILLKYDIKKRLGKGRTFREII----FLQEFGDHPNIIN-LRNVLRADNDKDIYLVFDFMDT-DLHAVIRKGNILKDVHK-------AYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIF</Hsp_qseq>
      <Hsp_hseq>INNDIDEPHVGDKVAIKQMVLSKQPRKELIVNEILVMKDSRHKNIVNFLEAYLRTDDD--LWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKS-------DNVLLDTRARVKITDFGFCARLTDKRSK-----RATMVGTPYWMAPEVVKQR------EYDEKIDVWSLGIMTIEMLEGEPPY</Hsp_hseq>
      <Hsp_midline>+N DID  H+  K  IK+ +   +  +E+I     + +   H NI+N L   LR D+D  +++V +FM+   L  +I       + H        AYI  +  +  K++H  ++IHRD K+        NVLLD    VK+ DFG    L   R +         V T ++ APE++          Y + +D+WS+G +  EML G+  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.8702</Hsp_bit-score>
      <Hsp_score>185</Hsp_score>
      <Hsp_evalue>1.77962e-14</Hsp_evalue>
      <Hsp_query-from>859</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>243</Hsp_hit-from>
      <Hsp_hit-to>466</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>119</Hsp_positive>
      <Hsp_gaps>60</Hsp_gaps>
      <Hsp_align-len>270</Hsp_align-len>
      <Hsp_qseq>REIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDTD--LHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLL--DGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVV-------CRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIM---SVIPQPSKEDVLAIKSEYGGSVLEKMGRQRQSLESXXXXXXXXXXXXXKRLLVFNPEKRLTAEEALGHPYV</Hsp_qseq>
      <Hsp_hseq>RELEVLQKL-NHPRIVRLKGFY--EDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGRE-ISRQILTAIKYIHSMGISHRDLK-------PDNILIEQDDPVLVKITDFGLAKV------QGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSG-STQDQLYKQIGRGSYHEGPLKD--FRISEE-----------ARDFIDS---------------LLQVDPNNRSTAAKALNHPWI</Hsp_hseq>
      <Hsp_midline>RE+  LQ+  +HP I+ L+     ++ +  Y+V +F+     +  V   G + +D  +  I+ Q+L A KYIHS  + HRD K       P N+L+  D    VK+ DFGLA+       +     +  +  T  Y APE++      V          Y+  VDMWS+GC+V  +L G   F G ST +Q+ + +   S    P K+    I  E            R  ++S               LL  +P  R TA +AL HP++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>7.65963e-14</Hsp_evalue>
      <Hsp_query-from>826</Hsp_query-from>
      <Hsp_query-to>1407</Hsp_query-to>
      <Hsp_hit-from>192</Hsp_hit-from>
      <Hsp_hit-to>376</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>205</Hsp_align-len>
      <Hsp_qseq>IKKRLGKGRTFREIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFM-DTDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDP-------ALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTS---TLNQIER</Hsp_qseq>
      <Hsp_hseq>LSKRLE--RTFAERSILSEI-EHPNIVKLFYSFH-DNSK-LYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLK-------PENCLLNQRGHLVLTDFGLSK--KSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKA------YSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQ</Hsp_hseq>
      <Hsp_midline>+ KRL   RTF E   L E  +HPNI+ L      DN K +YL+  ++   +L   +++   L +   ++   ++  A +++H+  V++RD K       P N LL+    + L DFGL++  K   D   D        AL   + T  Y APEILL         Y++  D +S+GC++ +ML+GK  + G++    +N+I++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.559</Hsp_bit-score>
      <Hsp_score>179</Hsp_score>
      <Hsp_evalue>1.04435e-13</Hsp_evalue>
      <Hsp_query-from>859</Hsp_query-from>
      <Hsp_query-to>1632</Hsp_query-to>
      <Hsp_hit-from>1313</Hsp_hit-from>
      <Hsp_hit-to>1560</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>122</Hsp_positive>
      <Hsp_gaps>82</Hsp_gaps>
      <Hsp_align-len>294</Hsp_align-len>
      <Hsp_qseq>REIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDTDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLAR----------SLKQIRDEPG-----------------DPALTEYVATRWYRAPEILLASPRRVVCRYTKGV----DMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSV----IPQ-PSKEDVLAIKSEYGGSVLEKMGRQRQSLESXXXXXXXXXXXXXKRLLVFNPEKRLTAEEALGHPYVAQ</Hsp_qseq>
      <Hsp_hseq>KEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEY-CEGGSLAALLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVK-------PENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGST-------TKGKLGADDVWSLGCVVLEMITGRR--PWANLDNEWAIMYHVAAGHTPQFPTKDEV----SSAGMKFLE-------------------------RCLIQNPSKRASAVELLMDPWIVQ</Hsp_hseq>
      <Hsp_midline>+E + + E  +HPNI++   V    +  +I++ +      L A++  G I  ++     T QLL+   Y+H   ++HRD K       P N+LLD    +K  DFG A+          S+ +I +  G                 + AL + + T  Y APE +  S        TKG     D+WS+GC+V EM+ G+   P  +  N+   +  V     PQ P+K++V    S  G   LE                         R L+ NP KR +A E L  P++ Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>3.05738e-13</Hsp_evalue>
      <Hsp_query-from>892</Hsp_query-from>
      <Hsp_query-to>1410</Hsp_query-to>
      <Hsp_hit-from>138</Hsp_hit-from>
      <Hsp_hit-to>293</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>174</Hsp_align-len>
      <Hsp_qseq>HPNIINLRNVLRADNDKDIYLVFDFM-DTDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERI</Hsp_qseq>
      <Hsp_hseq>HPNIVQFIDCF--EDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLG-------NIFFDSNYNLKIGDFGLAAVLANESERK-----YTICGTPNYIAPEVLMGKH----SGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERI</Hsp_hseq>
      <Hsp_midline>HPNI+   +    ++D ++Y++ +   +  L  ++++  +L +    + T Q+  A KY+HS  VIHRD K G       N+  D    +K+ DFGLA  L    +            T  Y APE+L+         ++  VD+WS+G ++  +L+GK  F         ERI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>3.50357e-13</Hsp_evalue>
      <Hsp_query-from>850</Hsp_query-from>
      <Hsp_query-to>1386</Hsp_query-to>
      <Hsp_hit-from>264</Hsp_hit-from>
      <Hsp_hit-to>424</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>184</Hsp_align-len>
      <Hsp_qseq>RTFREIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFM-----DTDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTS</Hsp_qseq>
      <Hsp_hseq>QIFRELQFNRSFQSE-YIVRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIK-------PQNILLNENGQVKLCDFG-------VSGEAVNSLATTFTGTSFYMAPERIQGQP------YSVTSDVWSLGLTILEVANGK--FPCSS</Hsp_hseq>
      <Hsp_midline>+ FRE+ F + F     I+    +   D +  IY+  ++M     D     ++ +G  + +     I   +L+   Y+H   VIHRD K       P N+LL+    VKLCDFG       +  E  +   T +  T +Y APE +   P      Y+   D+WS+G  + E+  GK  FP +S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>7.60241e-13</Hsp_evalue>
      <Hsp_query-from>862</Hsp_query-from>
      <Hsp_query-to>1419</Hsp_query-to>
      <Hsp_hit-from>173</Hsp_hit-from>
      <Hsp_hit-to>352</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>198</Hsp_align-len>
      <Hsp_qseq>EIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFM-DTDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPA-----------LTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSV</Hsp_qseq>
      <Hsp_hseq>EKLALQKLNGTKGIFKL--FFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIK-------PENILLDKNMKVKLTDFGTAKILPE---EPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRC------DIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKI</Hsp_hseq>
      <Hsp_midline>E + LQ+      I  L       ++  +Y + ++    D   +I+K   L +    Y   Q++ A   +H+  +IHRD K       P N+LLD    VKL DFG A+ L +   EP + A              +V T  Y +PE+L  +     C      D+W+ GCI+ +ML GK  F   +     +++M +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>1.05952e-12</Hsp_evalue>
      <Hsp_query-from>859</Hsp_query-from>
      <Hsp_query-to>1443</Hsp_query-to>
      <Hsp_hit-from>68</Hsp_hit-from>
      <Hsp_hit-to>242</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>198</Hsp_align-len>
      <Hsp_qseq>REIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFM-DTDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQ--IRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSVIPQPSKED</Hsp_qseq>
      <Hsp_hseq>REIQFLASLKQISNIT--RYYGSYLKDTSLWIIMEHCAGGSLRSLLRPGKI-DEKYIGVIMRELLVALKCIHKDNVIHRDIKA-------ANVLITNEGNVKLCDFGVAAQVNQTSLRRQ-------TMAGTPYWMAPEVIMEG-----VYYDTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIKSKP-PRLED</Hsp_hseq>
      <Hsp_midline>REI FL       NI   R       D  ++++ +      L +++R G I  + +   I  +LL A K IH  NVIHRD KA       +NVL+  E  VKLCDFG+A  + Q  +R +           T ++ APE+++         Y   VD+WS+G    E+  G   +     L  ++ I+   P P  ED</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>1.06343e-12</Hsp_evalue>
      <Hsp_query-from>817</Hsp_query-from>
      <Hsp_query-to>1374</Hsp_query-to>
      <Hsp_hit-from>650</Hsp_hit-from>
      <Hsp_hit-to>814</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>196</Hsp_align-len>
      <Hsp_qseq>KYDIKKRLGKGRTFREIIFLQEFGDHPNIINLRN--VLRADNDKDIYLVFDFMD----TDL--HAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCR--YTKGVDMWSVGCIVGEMLLGKAIF</Hsp_qseq>
      <Hsp_hseq>QMNLEKQPKKELIINEILVMK-GSKHPNIVNFIDSYVLKGD----LWVIMEYMEGGSLTDVVTHCILTEGQI------GAVCRETLSGLEFLHSKGVLHRDIKS-------DNILLSMEGDIKLTDFGFCAQINELNLK-----RTTMVGTPYWMAPE--------VVSRKEYGPKVDIWSLGIMIIEMIEGEPPY</Hsp_hseq>
      <Hsp_midline>+ +++K+  K     EI+ ++    HPNI+N  +  VL+ D    ++++ ++M+    TD+  H ++ +G I        +  + L   +++HS  V+HRD K+        N+LL  E  +KL DFG    + ++  +      T  V T ++ APE        VV R  Y   VD+WS+G ++ EM+ G+  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>1.74524e-12</Hsp_evalue>
      <Hsp_query-from>859</Hsp_query-from>
      <Hsp_query-to>1632</Hsp_query-to>
      <Hsp_hit-from>1081</Hsp_hit-from>
      <Hsp_hit-to>1312</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>120</Hsp_positive>
      <Hsp_gaps>58</Hsp_gaps>
      <Hsp_align-len>274</Hsp_align-len>
      <Hsp_qseq>REIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDTDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSL-----KQIRDEP------GDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSV----IPQ-PSKEDVLAIKSEYGGSVLEKMGRQRQSLESXXXXXXXXXXXXXKRLLVFNPEKRLTAEEALGHPYVAQ</Hsp_qseq>
      <Hsp_hseq>KEEMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEY-CEGGSLASLLDHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIK-------PENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSA---VKGKLGADDVWALGCVVLEMATGRR--PWSNLDNEWAIMYHVAAGRIPQLPNRDEMTAA----GRAFLE-------------------------RCLVQDPTMRATAVELLIDPWMIQ</Hsp_hseq>
      <Hsp_midline>+E + + E  +HPNI+    V    +  +I++ +      L +++  G I  ++     T++LL+   Y+H   V+HRD K       P N+LLD    +K  DFG AR++     + +R+           +L E + T  Y APE +  S    V       D+W++GC+V EM  G+   P ++  N+   +  V    IPQ P+++++ A     G + LE                         R LV +P  R TA E L  P++ Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.5514</Hsp_bit-score>
      <Hsp_score>166</Hsp_score>
      <Hsp_evalue>2.78923e-12</Hsp_evalue>
      <Hsp_query-from>796</Hsp_query-from>
      <Hsp_query-to>1386</Hsp_query-to>
      <Hsp_hit-from>86</Hsp_hit-from>
      <Hsp_hit-to>256</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>202</Hsp_align-len>
      <Hsp_qseq>IDSHILLKYDIKKRLGKGRTFREIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDTDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQ---IRDEPGDP--ALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTS</Hsp_qseq>
      <Hsp_hseq>INKKVLAKSDMQ-----GRIEREISYLRLLR-HPHIIKLYDVIKSKDE--IIMVIEYAGNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLK-------PENLLLDEHLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPE----------------VDVWSCGVILYVMLCRRLPFDDES</Hsp_hseq>
      <Hsp_midline>I+  +L K D++     GR  REI +L+    HP+II L +V+++ ++  I +V ++   +L   I + + + +        Q++ A +Y H   ++HRD K       P N+LLD    VK+ DFGL+  +     ++   G P  A  E ++ + Y  PE                VD+WS G I+  ML  +  F   S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>3.07375e-12</Hsp_evalue>
      <Hsp_query-from>859</Hsp_query-from>
      <Hsp_query-to>1635</Hsp_query-to>
      <Hsp_hit-from>80</Hsp_hit-from>
      <Hsp_hit-to>292</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>118</Hsp_positive>
      <Hsp_gaps>52</Hsp_gaps>
      <Hsp_align-len>262</Hsp_align-len>
      <Hsp_qseq>REIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDTD--LHAVIRKGNILKDVHKAYITY-QLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSVIPQPSKEDVLAIKSEYGGSVLEKMGRQRQSLESXXXXXXXXXXXXXKRLLVFNPEKRLTAEEALGHPYVAQF</Hsp_qseq>
      <Hsp_hseq>REIIIMK-LLNHPNVLRLYDVW--ETNTDLYLVLEYAEKGELFNLLVERGPLPE--HEAIRFFRQIIIGVSYCHALGIVHRDLK-------PENLLLDHKYNIKIADFGMAAL------ETEGKLLETSCGSPHYAAPEIVSGIPYQGFAS-----DVWSCGVILFALLTGR--LPFDEEDGNIRTLLLKVQ----------KGEFEMPSDDEISREAQDL--------------IRKILTVDPERRIKTRDILKHPLLQKY</Hsp_hseq>
      <Hsp_midline>REII ++   +HPN++ L +V   + + D+YLV ++ +     + ++ +G + +  H+A   + Q++    Y H+  ++HRD K       P N+LLD +  +K+ DFG+A        E     L     +  Y APEI+   P +         D+WS G I+  +L G+   P       I  ++  +           K E+     +++ R+ Q L              ++++L  +PE+R+   + L HP + ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>3.80662e-12</Hsp_evalue>
      <Hsp_query-from>1033</Hsp_query-from>
      <Hsp_query-to>1410</Hsp_query-to>
      <Hsp_hit-from>559</Hsp_hit-from>
      <Hsp_hit-to>669</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>126</Hsp_align-len>
      <Hsp_qseq>ITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERI</Hsp_qseq>
      <Hsp_hseq>FTRQILIGVAYLHKKNIIHRDIKG-------ANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQ--GSVFWMSPEVVKQTAT------TAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKI</Hsp_hseq>
      <Hsp_midline> T Q+L    Y+H  N+IHRD K        +N+L+D +  VK+ DFG+++ L  +  +    A  +   + ++ +PE++  +        T   D+WS GC+V EM  GK  FP  S +  I +I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>4.25359e-12</Hsp_evalue>
      <Hsp_query-from>856</Hsp_query-from>
      <Hsp_query-to>1374</Hsp_query-to>
      <Hsp_hit-from>259</Hsp_hit-from>
      <Hsp_hit-to>415</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>179</Hsp_align-len>
      <Hsp_qseq>FREIIFLQEF-GDHPNIINLRNVLRADNDKDIYLVFDFM-----DTDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIF</Hsp_qseq>
      <Hsp_hseq>FRELQFNKSFKSDY--IVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIK-------PQNILLNEKGEIKLCDFGVS-------GEAVNSLAMTFTGTSFYMAPERIQGQPYSVTC------DVWSLGLTLLEVAGGRFPF</Hsp_hseq>
      <Hsp_midline>FRE+ F + F  D+  I+    +   +    IY+  ++M     +     ++++G  + +     I   +L+   Y+H   VIHRD K       P N+LL+ +  +KLCDFG++        E  +     +  T +Y APE +   P  V C      D+WS+G  + E+  G+  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>7.88357e-12</Hsp_evalue>
      <Hsp_query-from>889</Hsp_query-from>
      <Hsp_query-to>1362</Hsp_query-to>
      <Hsp_hit-from>403</Hsp_hit-from>
      <Hsp_hit-to>541</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>161</Hsp_align-len>
      <Hsp_qseq>DHPNIINLRNVLRADNDKDIYLVFDFMDTD--LHAVIRKGNILKDVHKA-YITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLG</Hsp_qseq>
      <Hsp_hseq>DCPFIVPLKFSFQSP--EKLYFVLAFINGGELFYHLQKEGRF--DLSRARFYTAELLCALDNLHKLDVVYRDLK-------PENILLDYQGHIALCDFGLCK-LNMKDDDKTD----TFCGTPEYLAPELLLG------LGYTKAVDWWTLGVLLYEMLTG</Hsp_hseq>
      <Hsp_midline>D P I+ L+   ++   + +Y V  F++     + + ++G    D+ +A + T +LL A   +H  +V++RD K       P N+LLD +  + LCDFGL + L    D+  D     +  T  Y APE+LL         YTK VD W++G ++ EML G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>8.58889e-12</Hsp_evalue>
      <Hsp_query-from>898</Hsp_query-from>
      <Hsp_query-to>1365</Hsp_query-to>
      <Hsp_hit-from>433</Hsp_hit-from>
      <Hsp_hit-to>579</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>166</Hsp_align-len>
      <Hsp_qseq>NIINLRNVLRADNDKDIYLVFDFMD----TDLHAVIRKGNI------LKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGK</Hsp_qseq>
      <Hsp_hseq>NIVNFLEAYIID-DEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKS-------DNILLNSQGLVKITDFGFCVELTEKRSKRA-----TMVGTPYWMAPEIVNQKG------YDEKVDVWSLGIMLIEMIEGE</Hsp_hseq>
      <Hsp_midline>NI+N       D D++++++ ++M+    TD+   + + N       L +   AYI  +  +  K++H+  +IHRD K+        N+LL+ +  VK+ DFG    L + R +         V T ++ APEI+          Y + VD+WS+G ++ EM+ G+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>1.22588e-11</Hsp_evalue>
      <Hsp_query-from>859</Hsp_query-from>
      <Hsp_query-to>1635</Hsp_query-to>
      <Hsp_hit-from>163</Hsp_hit-from>
      <Hsp_hit-to>372</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>118</Hsp_positive>
      <Hsp_gaps>59</Hsp_gaps>
      <Hsp_align-len>264</Hsp_align-len>
      <Hsp_qseq>REIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDTD--LHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGEC-FVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKG-VDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSVIPQPSKEDVLAIKSEYGGSVL-EKMGRQRQSLESXXXXXXXXXXXXXKRLLVFNPEKRLTAEEALGHPYVAQF</Hsp_qseq>
      <Hsp_hseq>REIVIMKLIS-HTNVMALFEVW--ENKSELYLVLEYVDGGELFDYLVSKGK-LPEREAIHYFKQIVEGVSYCHSFNICHRDLK-------PENLLLDKKNRRIKIADFGMAAL------ELPNKLLKTSCGSPHYASPEIVMGRP------YHGGPSDVWSCGIVLFALLTGHLPFND----DNIKKLL-------------LKVQSGKYQMPSNLSSEARDLIS--------------KILVIDPEKRITTQEILKHPLIKKY</Hsp_hseq>
      <Hsp_midline>REI+ ++    H N++ L  V   +N  ++YLV +++D       ++ KG  L +    +   Q+++   Y HS N+ HRD K       P N+LLD +   +K+ DFG+A        E  +  L     +  Y +PEI++  P      Y  G  D+WS G ++  +L G   F      + I++++             +K + G   +   +  + + L S              ++LV +PEKR+T +E L HP + ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>1.88521e-11</Hsp_evalue>
      <Hsp_query-from>889</Hsp_query-from>
      <Hsp_query-to>1389</Hsp_query-to>
      <Hsp_hit-from>219</Hsp_hit-from>
      <Hsp_hit-to>390</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>185</Hsp_align-len>
      <Hsp_qseq>DHPNIINLRNVLRADNDKDIYLVFDFM-DTDLHAVIRKGNILKDVHKA---YITYQLLKATKYIHSGNVIHRDQKAGPLL---PLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKG-----------VDMWSVGCIVGEMLLGKAIFPGTST</Hsp_qseq>
      <Hsp_hseq>DHPNIIKVYHTF-CDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIV-------LADFGIAKDLNSNKER-----MHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGISPFYGDGS</Hsp_hseq>
      <Hsp_midline>DHPNII + +    D +  +Y+  D +   DL + + KG+ L  + +     I +Q+L+A  Y+H  +++HRD K   +L   P P   ++       L DFG+A+ L   ++      +   V T  Y APE+   + R+    +++             D+WS+G I   ML G + F G  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>2.10033e-11</Hsp_evalue>
      <Hsp_query-from>811</Hsp_query-from>
      <Hsp_query-to>1374</Hsp_query-to>
      <Hsp_hit-from>140</Hsp_hit-from>
      <Hsp_hit-to>301</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>189</Hsp_align-len>
      <Hsp_qseq>LLKYDIKKRLGKGRTFREIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFM-DTDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIF</Hsp_qseq>
      <Hsp_hseq>IIKYNLQKQ------FRREVEIQTSLNHPNLTKSYGYFH--DEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIK-------PENILIGFNNVIKLTDFGWS-----IINPPENRRKT-VCGTIDYLSPEMVESR------EYDHTIDAWALGVLAFELLTGAPPF</Hsp_hseq>
      <Hsp_midline>++KY+++K+      FR  + +Q   +HPN+          ++K +YL+ +++ + +++ ++R      D+  +   YQ+  A  Y+H  N+IHRD K       P N+L+     +KL DFG +     I + P +   T    T  Y +PE++ +        Y   +D W++G +  E+L G   F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>4.87197e-11</Hsp_evalue>
      <Hsp_query-from>850</Hsp_query-from>
      <Hsp_query-to>1374</Hsp_query-to>
      <Hsp_hit-from>169</Hsp_hit-from>
      <Hsp_hit-to>323</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>178</Hsp_align-len>
      <Hsp_qseq>RTFREIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDTD--LHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYT-KGVDMWSVGCIVGEMLLGKAIF</Hsp_qseq>
      <Hsp_hseq>RTVREA-SLGQILYHPHICRLFEMCTMSNH--FYMLFEYVSGGQLLDYIIQHGS-LKEHHARKFARGIASALQYLHANNIVHRDLKI-------ENIMISSSGEIKIIDFGLSNIFDYRKQ------LHTFCGSLYFAAPELLKAQP------YTGPEVDIWSFGIVLYVLVCGKVPF</Hsp_hseq>
      <Hsp_midline>RT RE   L +   HP+I  L  +    N    Y++F+++     L  +I+ G+ LK+ H       +  A +Y+H+ N++HRD K         N+++     +K+ DFGL+      +       L  +  + ++ APE+L A P      YT   VD+WS G ++  ++ GK  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>6.9903e-11</Hsp_evalue>
      <Hsp_query-from>889</Hsp_query-from>
      <Hsp_query-to>1362</Hsp_query-to>
      <Hsp_hit-from>400</Hsp_hit-from>
      <Hsp_hit-to>538</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>DHPNIINLRNVLRADNDKDIYLVFDFMDTD--LHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLG</Hsp_qseq>
      <Hsp_hseq>DCPFIVPLKFSFQSP--EKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIA-ELLCALDSLHKLDVIYRDLK-------PENILLDYQGHIALCDFGLCKLNMKDNDK-----TDTFCGTPEYLAPEILLGQ------GYTKTVDWWTLGILLYEMMTG</Hsp_hseq>
      <Hsp_midline>D P I+ L+   ++   + +YLV  F++     + +  +G       + YI  +LL A   +H  +VI+RD K       P N+LLD +  + LCDFGL +   +  D+        +  T  Y APEILL         YTK VD W++G ++ EM+ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>7.32607e-11</Hsp_evalue>
      <Hsp_query-from>781</Hsp_query-from>
      <Hsp_query-to>1389</Hsp_query-to>
      <Hsp_hit-from>68</Hsp_hit-from>
      <Hsp_hit-to>254</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>209</Hsp_align-len>
      <Hsp_qseq>TMNTDIDSHILLKYDIK-KRLGKGRTFREIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDT--DLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECF---VKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTST</Hsp_qseq>
      <Hsp_hseq>STNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLS-HPNIVSFKDWFES---KDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLK-------PENVLYVDKSENSPLVIADFGIAKQLKGEED-----LIYKAAGSLGYVAPEVLTQDGHGKPC------DIWSIGVITYTLLCGYSPFIAESV</Hsp_hseq>
      <Hsp_midline>+ N D+   ILLK  ++   +     + E+  LQ+   HPNI++ ++   +   KD + +   + T  +L   I       +V    I  Q+L A +Y+HS NV+HRD K       P NVL   +     + + DFG+A+ LK   D      + +   +  Y APE+L        C      D+WS+G I   +L G + F   S </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>9.40731e-11</Hsp_evalue>
      <Hsp_query-from>787</Hsp_query-from>
      <Hsp_query-to>1374</Hsp_query-to>
      <Hsp_hit-from>56</Hsp_hit-from>
      <Hsp_hit-to>239</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>203</Hsp_align-len>
      <Hsp_qseq>NTDIDSHILLKYDIKKRLGKGRT-----FREIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDTD--LHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIF</Hsp_qseq>
      <Hsp_hseq>NTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRL-HHPNIVAFKDWFES-KDK-FYIITQLAKGGELFDRILKKGKFTEE-DAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKS----DESPLVVADFGIAKRLKSDEELLYKPA-----GSLGYVAPEVLTQDGHGKPC------DIWSIGVITYTLLCGYSAF</Hsp_hseq>
      <Hsp_midline>NT+    + +K  IKK L   +      + E+  LQ    HPNI+  ++   +  DK  Y++            +++KG   ++     I  ++L A KY+HS N++HRD K   LL +  +     E  + + DFG+A+ LK   +    PA      +  Y APE+L        C      D+WS+G I   +L G + F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>1.08659e-10</Hsp_evalue>
      <Hsp_query-from>850</Hsp_query-from>
      <Hsp_query-to>1362</Hsp_query-to>
      <Hsp_hit-from>96</Hsp_hit-from>
      <Hsp_hit-to>248</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>173</Hsp_align-len>
      <Hsp_qseq>RTFREIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDF-MDTDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILL-ASPRRVVCRYTKGVDMWSVGCIVGEMLLG</Hsp_qseq>
      <Hsp_hseq>KIYREINALKHLS-HPNIVKLEEVLQ--NSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKL-------ENLLLDKNENLVITDFGFVNEFCS-RNE----LMKTSCGSPCYAAPELVISAEPYEA-----RKADIWSCGVILYAILAG</Hsp_hseq>
      <Hsp_midline>+ +REI  L+    HPNI+ L  VL+  N + I +V ++    + +  I+K   LK+++   +  QL+    YIHS  ++HRD K         N+LLD    + + DFG        R+E     +     +  Y APE+++ A P        +  D+WS G I+  +L G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>1.24525e-10</Hsp_evalue>
      <Hsp_query-from>820</Hsp_query-from>
      <Hsp_query-to>1449</Hsp_query-to>
      <Hsp_hit-from>90</Hsp_hit-from>
      <Hsp_hit-to>302</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>YDIKKRLGKGRTFREIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDTDLHAVIRKGNI-LKDVHKAYITYQ--------LLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSL----KQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSV-IPQPSKEDVL</Hsp_qseq>
      <Hsp_hseq>YSLQLKVENPRVNQEIEVMKR-CHHENVVELYEILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHSQGITHRDIK-------PSNLLISSNGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPE-LCSTEKEYSC--SSAIDIWSLGVTIYCLLFGKLPFNANSGLELFDSIINKPLEFPSYEEML</Hsp_hseq>
      <Hsp_midline>Y ++ ++   R  +EI  ++    H N++ L  +L       +YLV ++          +  + +K V  + +T+Q        ++   +Y+HS  + HRD K       PSN+L+     VK+ DFG+A S       I+        +  + T  + APE L ++ +   C  +  +D+WS+G  +  +L GK  F   S L   + I++  +  PS E++L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>1.32889e-10</Hsp_evalue>
      <Hsp_query-from>805</Hsp_query-from>
      <Hsp_query-to>1380</Hsp_query-to>
      <Hsp_hit-from>859</Hsp_hit-from>
      <Hsp_hit-to>1026</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>196</Hsp_align-len>
      <Hsp_qseq>HILLKYDIKKRLGKGRTFREIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDT-DLHAVIRKGNILKDVHKA-YITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEP--GDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPG</Hsp_qseq>
      <Hsp_hseq>NIIQNHDIES----ARAEKKVFLLATKTKHPFLTNLYCSFQTENR--IYFAMEFIGGGDLMWHVQNQRL--SVRRAKFYAAEVLLALKYFHDNGVIYRDLKL-------ENILLTPEGHIKIADYGLCK------DEMWYGNRTST-FCGTPEFMAPEILKEQ------EYTKAVDWWAFGVLLYQMLLCQSPFSG</Hsp_hseq>
      <Hsp_midline>+I+  +DI+      R  +++  L     HP + NL    + +N   IY   +F+   DL   ++   +   V +A +   ++L A KY H   VI+RD K         N+LL  E  +K+ D+GL +      DE   G+   T +  T  + APEIL          YTK VD W+ G ++ +MLL ++ F G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>3.20993e-10</Hsp_evalue>
      <Hsp_query-from>814</Hsp_query-from>
      <Hsp_query-to>1362</Hsp_query-to>
      <Hsp_hit-from>87</Hsp_hit-from>
      <Hsp_hit-to>248</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>184</Hsp_align-len>
      <Hsp_qseq>LKYDIKKRLGKGRTFREIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDT-DLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLG</Hsp_qseq>
      <Hsp_hseq>IKKDADKEI---KIYREINALKHLT-HPNIIYLEEVLQ--NSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKL-------ENLLLDKHENLVITDFGFVNEFFE-----DNELMKTSCGSPCYAAPELVVSTK----AYEARKADVWSCGVILYAMLAG</Hsp_hseq>
      <Hsp_midline>+K D  K +   + +REI  L+    HPNII L  VL+  N K I +V +F+   + +  I++   LK+     +  QL+    Y+H   ++HRD K         N+LLD    + + DFG      +      +  +     +  Y APE+++++         +  D+WS G I+  ML G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>4.13063e-10</Hsp_evalue>
      <Hsp_query-from>1042</Hsp_query-from>
      <Hsp_query-to>1419</Hsp_query-to>
      <Hsp_hit-from>818</Hsp_hit-from>
      <Hsp_hit-to>938</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>138</Hsp_align-len>
      <Hsp_qseq>QLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLA----RSLKQIR----DEPGDP-ALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFP---GTSTLNQIERIMSV</Hsp_qseq>
      <Hsp_hseq>QILEALSYIHSQGIIHRDLK-------PMNIFIDESRNVKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVLDGT-----GHYNEKIDMYSLGIIFFEM-----IYPFSTGMERVNILKKLRSV</Hsp_hseq>
      <Hsp_midline>Q+L+A  YIHS  +IHRD K       P N+ +D    VK+ DFGLA    RSL  ++    + PG    LT  + T  Y A E+L  +       Y + +DM+S+G I  EM     I+P   G   +N ++++ SV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>4.26896e-10</Hsp_evalue>
      <Hsp_query-from>859</Hsp_query-from>
      <Hsp_query-to>1374</Hsp_query-to>
      <Hsp_hit-from>76</Hsp_hit-from>
      <Hsp_hit-to>227</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>173</Hsp_align-len>
      <Hsp_qseq>REIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDT-DLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIF</Hsp_qseq>
      <Hsp_hseq>REIVIMKLLS-HPNVLSLYDVWETNNN--LYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLK-------PENLLLDSFYNIKIADFGMA-ALQTDAD-----LLETSCGSPHYAAPEIVSGLPYEGFAS-----DVWSCGVILFALLTGRLPF</Hsp_hseq>
      <Hsp_midline>REI+ ++    HPN+++L +V   +N+  +YL+ ++ +  +L  ++     L +        Q++    Y H+  ++HRD K       P N+LLD    +K+ DFG+A +L+   D      L     +  Y APEI+   P           D+WS G I+  +L G+  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>5.45901e-10</Hsp_evalue>
      <Hsp_query-from>850</Hsp_query-from>
      <Hsp_query-to>1374</Hsp_query-to>
      <Hsp_hit-from>190</Hsp_hit-from>
      <Hsp_hit-to>344</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>181</Hsp_align-len>
      <Hsp_qseq>RTFREIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDTD--LHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLAR---SLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYT-KGVDMWSVGCIVGEMLLGKAIF</Hsp_qseq>
      <Hsp_hseq>RTIREA-SLGQILYHPHICRLFEMCTLSNH--FYMLFEYVSGGQLLDYIIQHGSIREHQARKF-ARGIASALIYLHANNIVHRDLKI-------ENIMISDSSEIKIIDFGLSNIYDSRKQ---------LHTFCGSLYFAAPELLKANP------YTGPEVDVWSFGVVLFVLVCGKVPF</Hsp_hseq>
      <Hsp_midline>RT RE   L +   HP+I  L  +    N    Y++F+++     L  +I+ G+I +   + +    +  A  Y+H+ N++HRD K         N+++     +K+ DFGL+    S KQ         L  +  + ++ APE+L A+P      YT   VD+WS G ++  ++ GK  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>1.072e-09</Hsp_evalue>
      <Hsp_query-from>784</Hsp_query-from>
      <Hsp_query-to>1434</Hsp_query-to>
      <Hsp_hit-from>43</Hsp_hit-from>
      <Hsp_hit-to>290</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>75</Hsp_gaps>
      <Hsp_align-len>270</Hsp_align-len>
      <Hsp_qseq>MNTDIDSHILLKYDIKKRLGKGRTFR----EIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDT-DLHAVIRKGNILKD---------------------VHKAYI-TY--QLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLL--------DGECF-------------VKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTL---NQIERIMSVIPQPS</Hsp_qseq>
      <Hsp_hseq>LTSDKSQHVAIKEVSRAKLKNKKLLENLEIEIAILKKI-KHPHIVGLIDCERTSTD--FYLIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIK-------PQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFL------PNTSLAETLCGSPLYMAPEILNYQ------KYNAKADLWSVGTVVFEMCCGTPPFRASNHLELFKKIKRANDVITFPS</Hsp_hseq>
      <Hsp_midline>+ +D   H+ +K   + +L   +       EI  L++   HP+I+ L +  R   D   YL+ ++    DL  ++++   L +                     +H+A++ +Y  QL  A K++ S N++HRD K       P N+LL        D + F             +K+ DFG AR L      P          +  Y APEIL         +Y    D+WSVG +V EM  G   F  ++ L    +I+R   VI  PS</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>2.779e-09</Hsp_evalue>
      <Hsp_query-from>946</Hsp_query-from>
      <Hsp_query-to>1491</Hsp_query-to>
      <Hsp_hit-from>250</Hsp_hit-from>
      <Hsp_hit-to>457</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>216</Hsp_align-len>
      <Hsp_qseq>IYLVFDFM-DTDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARS-------------LKQIRDEPGDPALTEYVAT---RWY---RAPEI-----LLASPRRVVC------RYTKGVDMWSVGCIVGEMLLGKAIFPGTS---TLNQIERIMSVIPQPSKEDVLAIKSEYGGSVLEKM</Hsp_qseq>
      <Hsp_hseq>LYLAMEFVPGGDFRTLLINTRCLKSGHARFYISEMFCAVNALHDLGYTHRDLK-------PENFLIDAKGHIKLTDFGLAAGTISNERIESMKIRLEKIKDLEF-PAFTEKSIEDRRKMYNQLREKEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYDNLRRWKQTLRRPRQSDGRAAFSDRTWDLITRL</Hsp_hseq>
      <Hsp_midline>+YL  +F+   D   ++     LK  H  +   ++  A   +H     HRD K       P N L+D +  +KL DFGLA               L++I+D    PA TE       + Y   R  EI     ++ SP  +        +Y   VD WS+GC++ E L+G   F G+S   T + + R    + +P + D  A  S+    ++ ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YDL028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:400997:403291:-1 gene:YDL028C transcript:YDL028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MPS1 description:Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]</Hit_def>
  <Hit_accession>YDL028C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>9.3907e-09</Hsp_evalue>
      <Hsp_query-from>862</Hsp_query-from>
      <Hsp_query-to>1635</Hsp_query-to>
      <Hsp_hit-from>486</Hsp_hit-from>
      <Hsp_hit-to>719</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>66</Hsp_gaps>
      <Hsp_align-len>279</Hsp_align-len>
      <Hsp_qseq>EIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDTDLHAVI--RKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSN-VLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGV---------------DMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMS---VIPQPSKEDVLAIKSEYGGSVLEKMGRQRQSLESXXXXXXXXXXXXXKRLLVFNPEKRLTAEEALGHPYVAQF</Hsp_qseq>
      <Hsp_hseq>EIELLEKLKDQKRVIQLLDYEMGDGL--LYLIMECGDHDLSQILNQRSGMPLDFNFVRFYTKEMLLCIKVVHDAGIVHSDLK-------PANFVLVKG--ILKIIDFGIANAVPE---HTVNIYRETQIGTPNYMAPEALVA------MNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYGKPPYGSFQGQNRLLAIMNPDVKIPFPEH---TSNNEKIPKSAIELM----------------------KACLYRNPDKRWTVDKVLSSTFLQPF</Hsp_hseq>
      <Hsp_midline>EI  L++  D   +I L +    D    +YL+ +  D DL  ++  R G  L      + T ++L   K +H   ++H D K       P+N VL+ G   +K+ DFG+A ++ +      +      + T  Y APE L+A        YT+                 DMWS GCI+ +M+ GK  +      N++  IM+    IP P      +   +   S +E M                      K  L  NP+KR T ++ L   ++  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>1.64677e-08</Hsp_evalue>
      <Hsp_query-from>859</Hsp_query-from>
      <Hsp_query-to>1428</Hsp_query-to>
      <Hsp_hit-from>63</Hsp_hit-from>
      <Hsp_hit-to>231</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>195</Hsp_align-len>
      <Hsp_qseq>REIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDTDLHAVIRKG---NILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQI--RDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSVIPQ</Hsp_qseq>
      <Hsp_hseq>QEIFFLAEL-KSPLITNY--IATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKA-------ANILLNEEGMVKLGDFGVSGHIRSTLKRD--------TFVGTPYWMAPEVVCCE----VDGYNEKADIWSLGITTYELLKG---LPPLSKYDPM-KVMTNLPK</Hsp_hseq>
      <Hsp_midline>+EI FL E    P I N   +     D  +++V ++      + + K    N L +   ++I +++    KY+H    IHRD KA       +N+LL+ E  VKL DFG++  ++    RD         +V T ++ APE++       V  Y +  D+WS+G    E+L G    P  S  + + ++M+ +P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YOR267C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:822588:824867:-1 gene:YOR267C transcript:YOR267C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRK1 description:Protein kinase; implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005793]</Hit_def>
  <Hit_accession>YOR267C</Hit_accession>
  <Hit_len>759</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>1.68736e-08</Hsp_evalue>
      <Hsp_query-from>892</Hsp_query-from>
      <Hsp_query-to>1377</Hsp_query-to>
      <Hsp_hit-from>274</Hsp_hit-from>
      <Hsp_hit-to>420</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>162</Hsp_align-len>
      <Hsp_qseq>HPNIINLRNVLRADNDKDIYLVFDFMDTDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFP</Hsp_qseq>
      <Hsp_hseq>HPNVIETVDVFSDSKQNKYYEVMEYCPIDFFAVVMTGKMSRGEINCCLK-QLTEGVKYLHSMGLAHRDLKL-------DNCVMTSQGILKLIDFGSAVVFRYPF-EDGVTMAHGIVGSDPYLAPEVITSTKSYD----PQCVDIWSIGIIYCCMVLKR--FP</Hsp_hseq>
      <Hsp_midline>HPN+I   +V         Y V ++   D  AV+  G + +      +  QL +  KY+HS  + HRD K         N ++  +  +KL DFG A   +    E G       V +  Y APE++ ++         + VD+WS+G I   M+L +  FP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>2.90971e-08</Hsp_evalue>
      <Hsp_query-from>811</Hsp_query-from>
      <Hsp_query-to>1407</Hsp_query-to>
      <Hsp_hit-from>114</Hsp_hit-from>
      <Hsp_hit-to>297</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>208</Hsp_align-len>
      <Hsp_qseq>LLKYDIKKRLGKG---RTFREIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDT-DLHAVIRKGNILKDVHK-AYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDG-ECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEIL---LASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIER</Hsp_qseq>
      <Hsp_hseq>LISSKVKSRLSNNICLEAMYEVDIQTKIGRHQNIAALLDFF------DSYIIMEYCSGGDLYEAIKADAVPKKTKSITHIITQIMDAIEYVHNKGIYHRDIK-------PENILISGIDWTIKLTDWGLATTDKT--------SMDRNVGSERYMSPELFDSNLDIKERKEPYDCAKVDLWAMGIVFLNIVFHKNPF---SIANQSDK</Hsp_hseq>
      <Hsp_midline>L+   +K RL          E+    + G H NI  L +        D Y++ ++    DL+  I+   + K      +I  Q++ A +Y+H+  + HRD K       P N+L+ G +  +KL D+GLA + K         ++   V +  Y +PE+    L    R        VD+W++G +   ++  K  F   S  NQ ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>6.35826e-08</Hsp_evalue>
      <Hsp_query-from>808</Hsp_query-from>
      <Hsp_query-to>1416</Hsp_query-to>
      <Hsp_hit-from>354</Hsp_hit-from>
      <Hsp_hit-to>556</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>220</Hsp_align-len>
      <Hsp_qseq>ILLKYDIKKRLGKGRTFREIIFLQEFGDHPNIINLRNVLRADNDKD-IYLVFDF-MDTDLHAVI--RKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLA-RSLKQIRDEPGDPALTE------------YVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMS</Hsp_qseq>
      <Hsp_hseq>VLNKHEMIKRKKIKRVLTEQEILAT-SDHPFIVTLYHSFQT---KDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLK-------PENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGN------GHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILT</Hsp_hseq>
      <Hsp_midline>+L K+++ KR    R   E   L    DHP I+ L +  +    KD +YL  ++ M  +    +  RK   + +    +   +++ A +Y+H    I+RD K       P N+LL     V L DF L+ ++    +    D    +            +V T  Y APE++  +       +T  VD W++G ++ EML G   F G ++      I++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>7.59908e-08</Hsp_evalue>
      <Hsp_query-from>808</Hsp_query-from>
      <Hsp_query-to>1356</Hsp_query-to>
      <Hsp_hit-from>867</Hsp_hit-from>
      <Hsp_hit-to>1043</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>200</Hsp_align-len>
      <Hsp_qseq>ILLKYDIKKRLGKGRTFREIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDTDLHAVIRK------GNI-LKDV---------HKAYITY-QLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEML</Hsp_qseq>
      <Hsp_hseq>VVIKMIFKERILVDTWVRD----RKLGTIPSEIQIMATLNKNSQENILKLLDFFEDDDYYYIETPVHGETGSIDLFDVIEFKKDMVEHEAKLVFKQVVASIKHLHDQGIVHRDIK-------DENVIVDSHGFVKLIDFG---SAAYIKSGPFDV----FVGTMDYAAPEVLGGSSYK-----GKPQDIWALGVLLYTII</Hsp_hseq>
      <Hsp_midline>+++K   K+R+      R+    ++ G  P+ I +   L  ++ ++I  + DF + D +  I        G+I L DV         H+A + + Q++ + K++H   ++HRD K         NV++D   FVKL DFG   S   I+  P D     +V T  Y APE+L  S  +      K  D+W++G ++  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>8.22518e-08</Hsp_evalue>
      <Hsp_query-from>808</Hsp_query-from>
      <Hsp_query-to>1431</Hsp_query-to>
      <Hsp_hit-from>385</Hsp_hit-from>
      <Hsp_hit-to>583</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>218</Hsp_align-len>
      <Hsp_qseq>ILLKYDIKKRLGKGRTFREIIFLQEF---GDHPNIINLRNVLRADNDKDIYLVFDFMDT-DLHAVIRKGNILKDVHK---AYITYQLLKATKYI-HSGNVIHRDQKAGPLLPLPSNVLLDG-ECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPE-ILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIMSVIPQP</Hsp_qseq>
      <Hsp_hseq>IMATKEVRLELDEAK-FRQILMELEVLHKCNSPYIVDFYGAFFIEGA--VYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVK-------PTNILCSANQGTVKLCDFGVSGNLV------ASLAKTN-IGCQSYMAPERIKSLNPDRAT--YTVQSDIWSLGLSILEMALGRYPYPPETYDNIFSQLSAIVDGP</Hsp_hseq>
      <Hsp_midline>I+   +++  L + + FR+I+   E     + P I++       +    +Y+  ++MD   L  +  + + +  + +   A+I   ++   K +    N+IHRD K       P+N+L    +  VKLCDFG++ +L          A T  +  + Y APE I   +P R    YT   D+WS+G  + EM LG+  +P  +  N   ++ +++  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>9.41167e-08</Hsp_evalue>
      <Hsp_query-from>859</Hsp_query-from>
      <Hsp_query-to>1368</Hsp_query-to>
      <Hsp_hit-from>64</Hsp_hit-from>
      <Hsp_hit-to>220</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>181</Hsp_align-len>
      <Hsp_qseq>REIIFLQEFGDHPNIINLRNVLRADNDKD-IYLVFDFMDT-DLHAVIRKG-NILKDVHKAYITYQLLKATKYIH-SGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLAR-------SLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKA</Hsp_qseq>
      <Hsp_hseq>KEVVLQSKCSKHPNVLRL---IDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQFYFQ-QLVSAINYLHVECGVAHRDIK-------PENILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPP---------YMAPEVLYSEEG----YYADRTDIWSIGILLFVLLTGQT</Hsp_hseq>
      <Hsp_midline>+E++   +   HPN++ L   +  +  K+ ++++ +  D  DL   I     +  DV + Y   QL+ A  Y+H    V HRD K       P N+LLD    +KL DFGLA        +L+   D+ G P          Y APE+L +        Y    D+WS+G ++  +L G+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YAR018C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:170396:171703:-1 gene:YAR018C transcript:YAR018C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN3 description:Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol [Source:SGD;Acc:S000000071]</Hit_def>
  <Hit_accession>YAR018C</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>1.35133e-07</Hsp_evalue>
      <Hsp_query-from>1144</Hsp_query-from>
      <Hsp_query-to>1353</Hsp_query-to>
      <Hsp_hit-from>223</Hsp_hit-from>
      <Hsp_hit-to>281</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>39</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>70</Hsp_align-len>
      <Hsp_qseq>GECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEM</Hsp_qseq>
      <Hsp_hseq>SQVVVKLGDFGLAKSL-----ETSIQFATTYVGTPYYMSPEVLMDQP------YSPLSDIWSLGCVIFEM</Hsp_hseq>
      <Hsp_midline> +  VKL DFGLA+SL     E      T YV T +Y +PE+L+  P      Y+   D+WS+GC++ EM</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YBR097W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:436951:441315:1 gene:YBR097W transcript:YBR097W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VPS15 description:Serine/threonine protein kinase involved in vacuolar protein sorting; functions as a membrane-associated complex with Vps34p; active form recruits Vps34p to the Golgi membrane; interacts with the GDP-bound form of Gpa1p; myristoylated; a fraction is localized, with Vps34p, to nuclear pores at nucleus-vacuole junctions and may facilitate transcription elongation for genes positioned at the nuclear periphery [Source:SGD;Acc:S000000301]</Hit_def>
  <Hit_accession>YBR097W</Hit_accession>
  <Hit_len>1454</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>1.4924e-07</Hsp_evalue>
      <Hsp_query-from>736</Hsp_query-from>
      <Hsp_query-to>1374</Hsp_query-to>
      <Hsp_hit-from>27</Hsp_hit-from>
      <Hsp_hit-to>241</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>VSAVSRTA*QRHPDSTMNTDIDSHILLKYDIK-KRLGKGRTFREIIFLQEF--GDHPNIINLRNVLRADNDKDIYLVFDFMDTDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDF-GLARSLKQIRDEPGDPALTEYVATR--WYRAPE----ILLASPRRVVCRYTKGVDMWSVGCIVGEMLL-GKAIF</Hsp_qseq>
      <Hsp_hseq>VHYVSQLNSSRFLKTCKALDPNGEIVIKVFIKPKDQYSLRPFLQRIRAQSFKLGQLPHVLNYSKLI--ETNRAGYMIRQHLKNNLYDRLSLRPYLQDIELKFIAFQLLNALKDIHNLNIVHGDIKT-------ENILVTSWNWCILTDFAAFIKPVYLPEDNPGEFLFYFDTSKRRTCYLAPERFNSKLYQDGKSNNGRLTKEMDIFSLGCVIAEIFAEGRPIF</Hsp_hseq>
      <Hsp_midline>V  VS+    R   +    D +  I++K  IK K     R F + I  Q F  G  P+++N   ++  + ++  Y++   +  +L+  +     L+D+   +I +QLL A K IH+ N++H D K         N+L+    +  L DF    + +    D PG+       + R   Y APE     L    +    R TK +D++S+GC++ E+   G+ IF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>71</Hit_num>
  <Hit_id>YNL183C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:293137:295509:-1 gene:YNL183C transcript:YNL183C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NPR1 description:Protein kinase; stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p; negatively regulates Ldb19p-mediated endocytosis through phosphorylation of Ldb19p, which prevents its association with the plasma membrane; Npr1p activity is negatively regulated via phosphorylation by the TOR complex; NPR1 has a paralog, PRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005127]</Hit_def>
  <Hit_accession>YNL183C</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>2.45058e-07</Hsp_evalue>
      <Hsp_query-from>889</Hsp_query-from>
      <Hsp_query-to>1377</Hsp_query-to>
      <Hsp_hit-from>496</Hsp_hit-from>
      <Hsp_hit-to>640</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>167</Hsp_align-len>
      <Hsp_qseq>DHPNIINLRNVLRADNDKDIYLVFDFMDTDLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTE---YVATRWYRAPEILLASPRRVVCRYT-KGVDMWSVGCIVGEMLLGKAIFP</Hsp_qseq>
      <Hsp_hseq>NHPNIIETIEIVY-ENDR-ILQVMEYCEYDLFAIVMS-NKMSYEEICCCFKQILTGVQYLHSIGLAHRDLKL-------DNCVINEKGIVKLIDFGAA----VVFSYPFSKNLVEASGIVGSDPYLAPEVC------IFAKYDPRPVDIWSSAIIFACMILKK--FP</Hsp_hseq>
      <Hsp_midline>+HPNII    ++  +ND+ I  V ++ + DL A++   N +          Q+L   +Y+HS  + HRD K         N +++ +  VKL DFG A     +   P    L E    V +  Y APE+       +  +Y  + VD+WS   I   M+L K  FP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>72</Hit_num>
  <Hit_id>YFL029C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:78055:79161:-1 gene:YFL029C transcript:YFL029C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CAK1 description:Cyclin-dependent kinase-activating kinase; required for passage through the cell cycle; phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases [Source:SGD;Acc:S000001865]</Hit_def>
  <Hit_accession>YFL029C</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>2.46812e-07</Hsp_evalue>
      <Hsp_query-from>1015</Hsp_query-from>
      <Hsp_query-to>1350</Hsp_query-to>
      <Hsp_hit-from>128</Hsp_hit-from>
      <Hsp_hit-to>236</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>122</Hsp_align-len>
      <Hsp_qseq>DVHKAYITY--QLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECF-----VKLCDFGLARSL---KQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGE</Hsp_qseq>
      <Hsp_hseq>DVNRYSLSFFRQMVEGIAFLHENKIIHRDIK-------PQNIMLTNNTSTVSPKLYIIDFGISYDMANNSQTSAEPMDSKVTD-ISTGIYKAPEVLFG----VKC-YDGGVDVWSLLIIISQ</Hsp_hseq>
      <Hsp_midline>DV++  +++  Q+++   ++H   +IHRD K       P N++L          + + DFG++  +    Q   EP D  +T+ ++T  Y+APE+L      V C Y  GVD+WS+  I+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>73</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>3.12245e-07</Hsp_evalue>
      <Hsp_query-from>862</Hsp_query-from>
      <Hsp_query-to>1356</Hsp_query-to>
      <Hsp_hit-from>70</Hsp_hit-from>
      <Hsp_hit-to>212</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>168</Hsp_align-len>
      <Hsp_qseq>EIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFM-DTDLHAVIRKGN--ILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEML</Hsp_qseq>
      <Hsp_hseq>EISLLKNL-NHNNIVKYHGFIRKS--YELYILLEYCANGSLRRLISRSSTGLSENESKTYVT-QTLLGLKYLHGEGVIHRDIKAA-------NILLSADNTVKLADFGVSTIV-------NSSALTLAGTLNW-MAPEILGNRGASTLS------DIWSLGATVVEML</Hsp_hseq>
      <Hsp_midline>EI  L+   +H NI+     +R     ++Y++ ++  +  L  +I + +  + ++  K Y+T Q L   KY+H   VIHRD KA        N+LL  +  VKL DFG++  +          ALT      W  APEIL       +       D+WS+G  V EML</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>74</Hit_num>
  <Hit_id>YDR247W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:956013:957398:1 gene:YDR247W transcript:YDR247W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VHS1 description:Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; VHS1 has a paralog, SKS1, that arose from the whole genome duplication [Source:SGD;Acc:S000002655]</Hit_def>
  <Hit_accession>YDR247W</Hit_accession>
  <Hit_len>461</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>4.14777e-07</Hsp_evalue>
      <Hsp_query-from>856</Hsp_query-from>
      <Hsp_query-to>1344</Hsp_query-to>
      <Hsp_hit-from>106</Hsp_hit-from>
      <Hsp_hit-to>264</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>178</Hsp_align-len>
      <Hsp_qseq>FREIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDTDLH-AVIRKGNILKD---VHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRV-----------VCRYTKGVDMWSVGCIV</Hsp_qseq>
      <Hsp_hseq>YKEISLHLRVHHHKNIVTIHEVLQSA--VCTFIVMDYYPTDLFTSIVDNRHFVTNGLLVKKVFL--QICSALNYCHEHGIYHCDIK-------PENLLLDTEDNVFLCDFGLSTTSTYIK-----PNVC--IGSSYYMPPERISFDGRVSSSKSGGHKLGKVCPSCNG-DLWSLGIIL</Hsp_hseq>
      <Hsp_midline>++EI        H NI+ +  VL++      ++V D+  TDL  +++   + + +   V K ++  Q+  A  Y H   + H D K       P N+LLD E  V LCDFGL+ +   I+     P +   + + +Y  PE +    R             VC    G D+WS+G I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>75</Hit_num>
  <Hit_id>YPL026C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:500675:502183:-1 gene:YPL026C transcript:YPL026C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKS1 description:Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway; SKS1 has a paralog, VHS1, that arose from the whole genome duplication [Source:SGD;Acc:S000005947]</Hit_def>
  <Hit_accession>YPL026C</Hit_accession>
  <Hit_len>502</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>5.18808e-07</Hsp_evalue>
      <Hsp_query-from>793</Hsp_query-from>
      <Hsp_query-to>1344</Hsp_query-to>
      <Hsp_hit-from>89</Hsp_hit-from>
      <Hsp_hit-to>265</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>201</Hsp_align-len>
      <Hsp_qseq>DIDSHILLKYDIKKRLGKGRTFREIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDTDLHAVI-------RKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRV--------VCRY--TKGVDMWSVGCIV</Hsp_qseq>
      <Hsp_hseq>DLDSILQLT---ENELNRLPHYREIAFQLRVQSHGNIVKIHQVLESS--IATFIVMDYYDRDLFTSIVDDKHFVNHGILIKKVF-----LQLCSALDHCHRLGIYHCDIK-------PENVLLDRNDNAYLCDFGLSTKSKYL-------APNVCVGSSYYMAPERILYCLNTTTNGIHVDECCSSLPTDTGDIWSLGIIL</Hsp_hseq>
      <Hsp_midline>D+DS + L    +  L +   +REI F      H NI+ +  VL +      ++V D+ D DL   I         G ++K V       QL  A  + H   + H D K       P NVLLD      LCDFGL+   K +       A    V + +Y APE +L               C    T   D+WS+G I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>76</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>5.36482e-07</Hsp_evalue>
      <Hsp_query-from>1033</Hsp_query-from>
      <Hsp_query-to>1377</Hsp_query-to>
      <Hsp_hit-from>310</Hsp_hit-from>
      <Hsp_hit-to>403</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>117</Hsp_align-len>
      <Hsp_qseq>ITYQLLKATKYIH-SGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSL-KQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFP</Hsp_qseq>
      <Hsp_hseq>IAYGVLNGLDHLYRQYKIIHRDIK-------PSNVLINSKGQIKLCDFGVSKKLINSIAD--------TFVGTSTYMSPERIQGNV------YSIKGDVWSLGLMIIELVTGE--FP</Hsp_hseq>
      <Hsp_midline>I Y +L    +++    +IHRD K       PSNVL++ +  +KLCDFG+++ L   I D         +V T  Y +PE +  +       Y+   D+WS+G ++ E++ G+  FP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>77</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>7.07509e-07</Hsp_evalue>
      <Hsp_query-from>808</Hsp_query-from>
      <Hsp_query-to>1413</Hsp_query-to>
      <Hsp_hit-from>526</Hsp_hit-from>
      <Hsp_hit-to>730</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>221</Hsp_align-len>
      <Hsp_qseq>ILLKYDIKKRLGKGRTFREIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDF-MDTDLHAVI--RKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQ----IRDEPGDPALTE------------YVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIFPGTSTLNQIERIM</Hsp_qseq>
      <Hsp_hseq>VLSKDEMIKRNKIKRVLTEQEILAT-SNHPFIVTLYHSFQSEDY--LYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLK-------PENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRGN------GHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNIL</Hsp_hseq>
      <Hsp_midline>+L K ++ KR    R   E   L    +HP I+ L +  ++++   +YL  ++ M  +    +  RK   + +    +   ++  A +Y+H    I+RD K       P N+LL     + L DF L+   K     +        L +            +V T  Y APE++  +       +T  VD W++G ++ EML G   F G +T      I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>78</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>7.22374e-07</Hsp_evalue>
      <Hsp_query-from>1030</Hsp_query-from>
      <Hsp_query-to>1362</Hsp_query-to>
      <Hsp_hit-from>238</Hsp_hit-from>
      <Hsp_hit-to>352</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>130</Hsp_align-len>
      <Hsp_qseq>YITYQLLKATKYIHSGNVIHRDQKAGPLL--PLPSNVLLDGEC----------------FVKLCDFGLARSLKQIRDEPGDPALT-EYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLG</Hsp_qseq>
      <Hsp_hseq>HVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPF-YGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLRN--NTAKTPCGTIEYVASEVFTSK------------RYSMKVDMWSIGCVLFTLLCG</Hsp_hseq>
      <Hsp_midline>++  Q+  A K++H   ++HRD K   LL  P+P    LDG+                  VKL DFGLA+ L+   +    P  T EYVA+  + +             RY+  VDMWS+GC++  +L G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>79</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>1.12675e-06</Hsp_evalue>
      <Hsp_query-from>976</Hsp_query-from>
      <Hsp_query-to>1374</Hsp_query-to>
      <Hsp_hit-from>1191</Hsp_hit-from>
      <Hsp_hit-to>1304</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>133</Hsp_align-len>
      <Hsp_qseq>DLHAVIRKGNILKDVHKAYITYQLLKATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGECFVKLCDFGLARSLKQIRDEPGDPALTEYVATRWYRAPEILLASPRRVVCRYTKGVDMWSVGCIVGEMLLGKAIF</Hsp_qseq>
      <Hsp_hseq>DLFDLIEFKTNMTEFEAKLIFKQVVAGIKHLHDQGIVHRDIKD-------ENVIVDSKGFVKIIDFG---SAAYVKSGPFDV----FVGTIDYAAPEVLGGNPYE-----GQPQDIWAIGILLYTVVFKENPF</Hsp_hseq>
      <Hsp_midline>DL  +I     + +     I  Q++   K++H   ++HRD K         NV++D + FVK+ DFG   S   ++  P D     +V T  Y APE+L  +P        +  D+W++G ++  ++  +  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>80</Hit_num>
  <Hit_id>YHR079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:258244:261591:-1 gene:YHR079C transcript:YHR079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IRE1 description:Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; role in homeostatic adaptation to ER stress; Kar2p binds inactive Ire1p and releases from it upon ER stress [Source:SGD;Acc:S000001121]</Hit_def>
  <Hit_accession>YHR079C</Hit_accession>
  <Hit_len>1115</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>2.2336e-06</Hsp_evalue>
      <Hsp_query-from>862</Hsp_query-from>
      <Hsp_query-to>1356</Hsp_query-to>
      <Hsp_hit-from>715</Hsp_hit-from>
      <Hsp_hit-to>914</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>207</Hsp_align-len>
      <Hsp_qseq>EIIFLQEFGDHPNIINLRNVLRADNDKDIYLVFDFMDTDLHAVIRKGNILKD---VHKAYITYQLLK----ATKYIHSGNVIHRDQKAGPLLPLPSNVLLDGE------CFVKLCDFGLARSL----KQIRDEPGDPALTEYVATRWYRAPEIL-------------LASPRRVVC------------RYTKGVDMWSVGCIVGEML</Hsp_qseq>
      <Hsp_hseq>EIKLLTESDDHPNVI--RYYCSETTDRFLYIALELCNLNLQDLVESKNVSDENLKLQKEYNPISLLRQIASGVAHLHSLKIIHRDLKPQNILVSTSSRFTADQQTGAENLRILISDFGLCKKLDSGQSSFRTNLNNPS-----GTSGWRAPELLEESNNLQCQVETEHSSSRHTVVSSDSFYDPFTKRRLTRSIDIFSMGCVFYYIL</Hsp_hseq>
      <Hsp_midline>EI  L E  DHPN+I  R       D+ +Y+  +  + +L  ++   N+  +   + K Y    LL+       ++HS  +IHRD K   +L   S+     +        + + DFGL + L       R    +P+      T  +RAPE+L              +S R  V             R T+ +D++S+GC+   +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>1910263615</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056610-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.29 eAED:0.29 QI:0|0.5|0.33|1|1|1|3|863|159</Iteration_query-def>
  <Iteration_query-len>1343</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>93</Statistics_hsp-len>
      <Statistics_eff-space>814294518</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056611-RA transcript Note:&quot;Similar to C8orf76 Uncharacterized protein C8orf76 (Homo sapiens)&quot; offset:45 AED:0.52 eAED:0.52 QI:45|1|0.5|1|1|1|2|0|81</Iteration_query-def>
  <Iteration_query-len>291</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>68</Statistics_hsp-len>
      <Statistics_eff-space>71492743</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056612-RA transcript Note:&quot;Similar to Bag2 BAG family molecular chaperone regulator 2 (Mus musculus)&quot; offset:0 AED:0.05 eAED:0.05 QI:0|-1|0|1|-1|1|1|0|156</Iteration_query-def>
  <Iteration_query-len>471</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>82</Statistics_hsp-len>
      <Statistics_eff-space>177965025</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0033855-RA transcript Note:&quot;Similar to Rab23 Ras-related protein Rab-23 (Mus musculus)&quot; offset:0 AED:0.41 eAED:0.54 QI:0|0|0|0.6|0.25|0.2|5|345|153</Iteration_query-def>
  <Iteration_query-len>807</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YFL005W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:130334:130981:1 gene:YFL005W transcript:YFL005W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SEC4 description:Rab family GTPase; essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane [Source:SGD;Acc:S000001889]</Hit_def>
  <Hit_accession>YFL005W</Hit_accession>
  <Hit_len>215</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>43.8986</Hsp_bit-score>
      <Hsp_score>102</Hsp_score>
      <Hsp_evalue>8.51855e-06</Hsp_evalue>
      <Hsp_query-from>295</Hsp_query-from>
      <Hsp_query-to>369</Hsp_query-to>
      <Hsp_hit-from>68</Hsp_hit-from>
      <Hsp_hit-to>92</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>18</Hsp_identity>
      <Hsp_positive>20</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>25</Hsp_align-len>
      <Hsp_qseq>EVRLMLWDTAGQEEFDAITKAYYRG</Hsp_qseq>
      <Hsp_hseq>KVKLQLWDTAGQERFRTITTAYYRG</Hsp_hseq>
      <Hsp_midline>+V+L LWDTAGQE F  IT AYYRG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>88</Statistics_hsp-len>
      <Statistics_eff-space>422321327</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056616-RA transcript Note:&quot;Similar to PTK2 Focal adhesion kinase 1 (Homo sapiens)&quot; offset:80 AED:0.11 eAED:0.11 QI:80|0.28|0.27|1|0.95|0.90|22|1081|788</Iteration_query-def>
  <Iteration_query-len>3528</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.1889</Hsp_bit-score>
      <Hsp_score>204</Hsp_score>
      <Hsp_evalue>7.3759e-17</Hsp_evalue>
      <Hsp_query-from>1140</Hsp_query-from>
      <Hsp_query-to>1640</Hsp_query-to>
      <Hsp_hit-from>7</Hsp_hit-from>
      <Hsp_hit-to>181</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>181</Hsp_align-len>
      <Hsp_qseq>STRDYEIPRDEVELVTCIGEGQFGDVHKGIYKSPSDPNMPVAVKTCKESCSDSVREKFLQEAYTMRQFDHPHIVKLIG-VISDPPIWIVMELCKYGESNCYTLDLGTLI---------LYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSRH----MEDDTYYKGVCMW</Hsp_qseq>
      <Hsp_hseq>SIRSRTPPSKLYSIQSCIGRGNFGDVYKAVDRVTQEI---VAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYC--GGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRDTFV-GTPYW</Hsp_hseq>
      <Hsp_midline>S R    P     + +CIG G FGDV+K + +   +    VA+K      SD   E   QE + + +   P I   I  ++ D  +WIVME C  G  +C  L   + +           I++++  L YL  ++ +HRDI A N+L++    VKL DFG+S H    ++ DT+  G   W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.559</Hsp_bit-score>
      <Hsp_score>179</Hsp_score>
      <Hsp_evalue>1.37086e-13</Hsp_evalue>
      <Hsp_query-from>1176</Hsp_query-from>
      <Hsp_query-to>1652</Hsp_query-to>
      <Hsp_hit-from>42</Hsp_hit-from>
      <Hsp_hit-to>198</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>168</Hsp_align-len>
      <Hsp_qseq>ELVTCIGEGQFGDVHKGIYKSPSDPNMPVAVKTCKESCSDSVREKFLQEAYTMRQFDHPHIVKLIGVI-SDPPIWIVMELCKYGE--------SNCYTLDLGTLILYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSRHMEDDTYYKGVCMWEILM</Hsp_qseq>
      <Hsp_hseq>KILKQIGEGSFGKVYLALHR-------PTHRKVCLKT-SDKNDPNIVREVFYHRQFDFPYITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFA---QISGAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTRECMTKTTLETVCGTTVYM</Hsp_hseq>
      <Hsp_midline>+++  IGEG FG V+  +++       P   K C ++ SD      ++E +  RQFD P+I KL  VI ++  +W+ +E C   E             L+ G L     Q+S A+ Y  S   VHRD+   N+L+      KL DFG +R     T  + VC   + M</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>8.17194e-12</Hsp_evalue>
      <Hsp_query-from>1176</Hsp_query-from>
      <Hsp_query-to>1781</Hsp_query-to>
      <Hsp_hit-from>56</Hsp_hit-from>
      <Hsp_hit-to>269</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>216</Hsp_align-len>
      <Hsp_qseq>ELVTCIGEGQFGDVHKGIYKSPSDPNMPVAVKTCKESCSDSVREKFLQEAYTMRQFDHPHIVKLIGVI-SDPPIWIVMELCKYGESNCYTLDLGTLI-----LYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSRHMEDDTYYKGVC------MWEILM--FGVKPFQGVKNNDIIGRIENGERLPMPHNCPPTLYSIMTNDIY</Hsp_qseq>
      <Hsp_hseq>QIVKTLGEGSFGKV-KLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAG-NELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVY</Hsp_hseq>
      <Hsp_midline>++V  +GEG FG V K  Y + +   + + +   K      ++ +  +E   +R   HPHI+KL  VI S   I +V+E     E   Y +    +       +  Q+ +A+ Y    KIVHRD+   N+L+     VK+ADFGLS  M D  + K  C        E++       P   V +  +I  +    RLP      P L+  ++N +Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>6.17146e-11</Hsp_evalue>
      <Hsp_query-from>1191</Hsp_query-from>
      <Hsp_query-to>1598</Hsp_query-to>
      <Hsp_hit-from>13</Hsp_hit-from>
      <Hsp_hit-to>156</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>147</Hsp_align-len>
      <Hsp_qseq>IGEGQFGDVHKGIYKSPSDPNMPVAVKTCKESCSDSVREKFLQEAYTMRQFDHPHIVKLIGVI-SDPPIWIVME-----LCKYGESNCYT-----LDLGTLILYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSR</Hsp_qseq>
      <Hsp_hseq>LGNGTYATVYKGLNKTTG---VYVALKEVKLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLAR</Hsp_hseq>
      <Hsp_midline>+G G +  V+KG+ K+     + VA+K  K    +      ++E   M++  H +IV+L  VI ++  + +V E     L KY +S         L+L  +  + +QL   L++    KI+HRD+  +N+L++    +KL DFGL+R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>1.45581e-10</Hsp_evalue>
      <Hsp_query-from>1296</Hsp_query-from>
      <Hsp_query-to>1634</Hsp_query-to>
      <Hsp_hit-from>144</Hsp_hit-from>
      <Hsp_hit-to>262</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>119</Hsp_align-len>
      <Hsp_qseq>SVREKFLQEAYTMRQFDHPHIVKLIGVISDPP-IWIVMELCKYGESNCYTLDLGTL--IL---YIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSRHMEDDTYYKGVC</Hsp_qseq>
      <Hsp_hseq>NLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTVC</Hsp_hseq>
      <Hsp_midline>+++++F +E       +HP++ K  G   D   ++++ME    GE        G    IL   YIYQ++ AL Y+  K I+HRDI   N+L+   + +KL DFG S     +   K VC</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>2.59469e-10</Hsp_evalue>
      <Hsp_query-from>1116</Hsp_query-from>
      <Hsp_query-to>1595</Hsp_query-to>
      <Hsp_hit-from>6</Hsp_hit-from>
      <Hsp_hit-to>168</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>167</Hsp_align-len>
      <Hsp_qseq>DEDTYNMPSTRDYEIPRDEVELVTCIGEGQFGDVHKGIYKSPSDPNMPVAVKTCKESCSDSVREKFLQEAYTMRQFDHPHIVKLIGVISDP-PIWIVMELCKYGE------SNCYTLDLGTLILYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLS</Hsp_qseq>
      <Hsp_hseq>DTDRVNLTPIQRASEKSVQYHLKQVIGRGSYGVVYKAINK---HTDQVVAIKEVVYENDEELND-IMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVS</Hsp_hseq>
      <Hsp_midline>D D  N+   +       +  L   IG G +G V+K I K     +  VA+K       + + +  + E   ++  +H +IVK  G I     ++I++E C  G        +   L       Y+ Q    L YL  + ++HRDI A N+L+S+ + VKLADFG+S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>2.84095e-10</Hsp_evalue>
      <Hsp_query-from>1185</Hsp_query-from>
      <Hsp_query-to>1598</Hsp_query-to>
      <Hsp_hit-from>1038</Hsp_hit-from>
      <Hsp_hit-to>1181</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>148</Hsp_align-len>
      <Hsp_qseq>TCIGEGQFGDVHKGIYKSPSDPNMPVAVKTCKESCSDSVREKF---LQEAYTMRQFDHPHIVKLIGV-ISDPPIWIVMELCKYGESNCYTLDLGTL------ILYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSR</Hsp_qseq>
      <Hsp_hseq>SFIGGGTFGQVYSAINLENGEI---LAVKEIKIHDTTTMKKIFPLIKEEMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEYCE-GGSLASLLDHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDFNGIIKYVDFGTAR</Hsp_hseq>
      <Hsp_midline>+ IG G FG V+  I     +    +AVK  K   + ++++ F    +E   +   +HP+IV+  GV +    + I ME C+ G S    LD G +       +Y ++L   L+YL    +VHRDI   N+L+     +K  DFG +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>3.25398e-10</Hsp_evalue>
      <Hsp_query-from>1185</Hsp_query-from>
      <Hsp_query-to>1634</Hsp_query-to>
      <Hsp_hit-from>50</Hsp_hit-from>
      <Hsp_hit-to>211</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>162</Hsp_align-len>
      <Hsp_qseq>TCIGEGQFGDVHKGIYKSPSDPNMP--VAVKTCKESC--SDSVRE-KFLQEAYTMRQFDHPHIVKLIGVISDPP-IWIVMELCKYGESNCYT-----LDLGTLILYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFG-LSRHMEDDTYYKGVC</Hsp_qseq>
      <Hsp_hseq>STLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMKTSC</Hsp_hseq>
      <Hsp_midline>+ +GEG+FG V  G  K+ S   +P  VA+K  +      D+ +E K  +E   ++   HP+I+ L  V+ +   I IV+E    GE   Y      L   +      QL + ++Y+  K +VHRD+   N+L+   + + + DFG ++   ED+   K  C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>3.26742e-10</Hsp_evalue>
      <Hsp_query-from>1191</Hsp_query-from>
      <Hsp_query-to>1709</Hsp_query-to>
      <Hsp_hit-from>88</Hsp_hit-from>
      <Hsp_hit-to>294</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>212</Hsp_align-len>
      <Hsp_qseq>IGEGQFGDVHKGIYKSPSDPNMPVAVKTCKESC--SDSVREKFLQEAYTMRQFDHPHIVKLIGVISD-PPIWIVMELCKYGE-----SNCYTLDLGTLILYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLS---------------------------RH----MEDDTYYKGVCMWEILMFGVKPFQGVKNNDIIGRIE</Hsp_qseq>
      <Hsp_hseq>LGEGGFARC----FQIKDDSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLI-GKPPFQARDVNTIYERIK</Hsp_hseq>
      <Hsp_midline>+GEG F       ++   D     A KT  ++   S+  R+K L E    +   HP+IV+ I    D   ++I++E+C  G           L    +  +  Q+  A+ Y+ S++++HRD+   N+   S   +K+ DFGL+                           +H     E D +  GV ++ +L+ G  PFQ    N I  RI+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>4.29985e-10</Hsp_evalue>
      <Hsp_query-from>1191</Hsp_query-from>
      <Hsp_query-to>1598</Hsp_query-to>
      <Hsp_hit-from>14</Hsp_hit-from>
      <Hsp_hit-to>159</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>146</Hsp_align-len>
      <Hsp_qseq>IGEGQFGDVHKGIYKSPSDPNMPVAVKTCK-ESCSDSVREKFLQEAYTMRQFDHPHIVKLIGVI-SDP-PIWIVME-----LCKYGESNCYTLDLGTLIL--YIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSR</Hsp_qseq>
      <Hsp_hseq>VGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLAR</Hsp_hseq>
      <Hsp_midline>+GEG +G V+K +   P      VA+K  + ES  + V    ++E   +++    +IV+L  ++ SD   +++V E     L +Y E       LG  I+  ++ QL   ++Y  S +I+HRD+  +N+L++    +KL DFGL+R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>7.86887e-10</Hsp_evalue>
      <Hsp_query-from>1191</Hsp_query-from>
      <Hsp_query-to>1640</Hsp_query-to>
      <Hsp_hit-from>189</Hsp_hit-from>
      <Hsp_hit-to>345</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>166</Hsp_align-len>
      <Hsp_qseq>IGEGQFGDVHKGIYKSPSDPNMPVAVKTCKESCSDSVREKF----LQEAYTMRQFDHPHI--VKLIGVISDPPIWIVMELCKYGESNCYTLDLGTLILYIY--------QLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSRHMEDDTYYKG--VCMW</Hsp_qseq>
      <Hsp_hseq>VGEGTYGKVYKA---KNTNTEKLVALKKLRLQGE---REGFPITSIREIKLLQSFDHPNVSTIKEIMVESQKTVYMIFE---YADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKMNSRADYTNRVITLW</Hsp_hseq>
      <Hsp_midline>+GEG +G V+K      ++    VA+K  +       RE F    ++E   ++ FDHP++  +K I V S   ++++ E   Y +++   L L   +   +        QL   + YL   KI+HRD+   N+L+ +   +K+ DFGL+R M     Y    + +W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>9.88158e-10</Hsp_evalue>
      <Hsp_query-from>1191</Hsp_query-from>
      <Hsp_query-to>1634</Hsp_query-to>
      <Hsp_hit-from>30</Hsp_hit-from>
      <Hsp_hit-to>228</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>55</Hsp_gaps>
      <Hsp_align-len>201</Hsp_align-len>
      <Hsp_qseq>IGEGQFGDVHKGIYKSPSDPNMPVAVKTCKESC--SDSVREKFLQEAYTMRQFDHPHIVKLIGV-ISDPPIWIVMELCKYGE-----------------------------SNCYTLDLGTLILYIYQLSTALSYLESKKIVHRDIAARNVLVSSA---------------------DCVKLADFGLSRHMEDDTYYKGVC</Hsp_qseq>
      <Hsp_hseq>IGKGSFATVYRG--HLTSDKSQHVAIKEVSRAKLKNKKLLENLEIEIAILKKIKHPHIVGLIDCERTSTDFYLIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLC</Hsp_hseq>
      <Hsp_midline>IG+G F  V++G     SD +  VA+K    +   +  + E    E   +++  HPHIV LI    +    +++ME C  G+                              N   L    ++ Y+ QL++AL +L SK +VHRDI  +N+L+S+                        +K+ADFG +R + + +  + +C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>2.21634e-09</Hsp_evalue>
      <Hsp_query-from>1188</Hsp_query-from>
      <Hsp_query-to>1661</Hsp_query-to>
      <Hsp_hit-from>28</Hsp_hit-from>
      <Hsp_hit-to>195</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>180</Hsp_align-len>
      <Hsp_qseq>CIGEGQFGDVHKG-------IYKSPSDPNMPVAVKTCK-ESCSDSVR--EKFLQEAYTMRQFDHPHIVKLIGV-ISDPPIWIVMELCKYGESNCY----TLDLGTLILYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSRHMEDDTYYK----GVCMW---EILMFGV</Hsp_qseq>
      <Hsp_hseq>VIGRGKFGVVYKGYNVKTGRVY----------AIKVLNLDSDSDEVEDVQREIQFLASLKQISN--ITRYYGSYLKDTSLWIIMEHCAGGSLRSLLRPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGV</Hsp_hseq>
      <Hsp_midline> IG G+FG V+KG       +Y          A+K    +S SD V   ++ +Q   +++Q  +  I +  G  + D  +WI+ME C  G          +D   + + + +L  AL  +    ++HRDI A NVL+++   VKL DFG++  +   +  +    G   W   E++M GV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>2.34815e-09</Hsp_evalue>
      <Hsp_query-from>1266</Hsp_query-from>
      <Hsp_query-to>1595</Hsp_query-to>
      <Hsp_hit-from>178</Hsp_hit-from>
      <Hsp_hit-to>299</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>126</Hsp_align-len>
      <Hsp_qseq>VKTCKESCSDSVREKFLQEAYTMRQFDHPHIVKLIGVISD---PPIWIVMELCKYGE-----SNCYTLDLGTLILYIYQ--------LSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLS</Hsp_qseq>
      <Hsp_hseq>IKSSKISENDKIK----REIAIMKKCHHKHVVQLIEVLDDLKSRKIYLVLEYCSRGEVKWCPPDCMESDAKGPSLLSFQETREILRGVVLGLEYLHYQGIIHRDIKPANLLISGDGTVKISDFGVS</Hsp_hseq>
      <Hsp_midline>+K+ K S +D ++    +E   M++  H H+V+LI V+ D     I++V+E C  GE      +C   D     L  +Q        +   L YL  + I+HRDI   N+L+S    VK++DFG+S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>3.82473e-09</Hsp_evalue>
      <Hsp_query-from>1122</Hsp_query-from>
      <Hsp_query-to>1619</Hsp_query-to>
      <Hsp_hit-from>78</Hsp_hit-from>
      <Hsp_hit-to>241</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>181</Hsp_align-len>
      <Hsp_qseq>DTYNMPSTRDYEIPRDEVELVTCIGEGQFGDVHKGIYKSPSDPNMPVAVKTCKESCSDSVR--EKFLQEAYTMRQFDHPHIVKLIGVISDPP-IWIVMELCKYGESNCYTLDLGTLI------------LYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSRHMEDDTY</Hsp_qseq>
      <Hsp_hseq>DTSGKYSLSDFQILR-------TLGTGSFGRVH--LIRSNHNGRF-YALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGE-------LFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTY</Hsp_hseq>
      <Hsp_midline>DT    S  D++I R        +G G FG VH  + +S  +     A+KT K+     ++  E    E   +    HP I+++ G   D   +++VM+  + GE       L +L+             Y  ++  AL YL SK I++RD+   N+L+     +K+ DFG ++++ D TY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>4.22619e-09</Hsp_evalue>
      <Hsp_query-from>1146</Hsp_query-from>
      <Hsp_query-to>1634</Hsp_query-to>
      <Hsp_hit-from>195</Hsp_hit-from>
      <Hsp_hit-to>356</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>173</Hsp_align-len>
      <Hsp_qseq>RDYEIPRDEVELVTCIGEGQFGDVHKGIYKSPSDPNMPVAVKTCKESCSDSVREKFLQEAYTMRQFDHPHIVKLIGVISDP-PIWIVMELCKYGE-------SNCYTLDLGTLILYIYQLSTALSYLESKKIVHRDIAARNVLVSSAD--CVKLADFGLSRHMEDDTYYKGVC</Hsp_qseq>
      <Hsp_hseq>KDFSII-DEV-----VGQGAFATVKKAIERTTGKT---FAVKIISKRKVIGNMDGVTRELEVLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISR--QILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMKTFC</Hsp_hseq>
      <Hsp_midline>+D+ I  DEV     +G+G F  V K I ++        AVK   +       +   +E   +++ +HP IV+L G   D    ++VME    G+             D G  I    Q+ TA+ Y+ S  I HRD+   N+L+   D   VK+ DFGL++   + ++ K  C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>4.87342e-09</Hsp_evalue>
      <Hsp_query-from>1191</Hsp_query-from>
      <Hsp_query-to>1613</Hsp_query-to>
      <Hsp_hit-from>1272</Hsp_hit-from>
      <Hsp_hit-to>1418</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>151</Hsp_align-len>
      <Hsp_qseq>IGEGQFGDVHKGIYKSPSDPNMPVAVKTCKESCSDSVREKF---LQEAYTMRQFDHPHIVKLIGV-ISDPPIWIVMELCKYGESNCYTLDLGTL------ILYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSRHMEDD</Hsp_qseq>
      <Hsp_hseq>IGGGTFGRVYSAV---DLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCE-GGSLAALLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANN</Hsp_hseq>
      <Hsp_midline>IG G FG V+  +     D    +AVK      S S+++ F    +E   +   +HP+IV   GV +    + I ME C+ G S    L+ G +       +Y  QL   L+YL    IVHRD+   N+L+     +K  DFG ++ + ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>5.33109e-09</Hsp_evalue>
      <Hsp_query-from>1134</Hsp_query-from>
      <Hsp_query-to>1598</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>166</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>170</Hsp_align-len>
      <Hsp_qseq>MPSTRDYEIPRDEVELVTCIGEGQFGDVHKGIYKSPSDPNMPVAVKTCKESCSDSVREKFLQEAYTMRQF-DHPHIVKLIGVISDPPI------WIVMELCKYG--------ESNCYTLDLGTLILYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSR</Hsp_qseq>
      <Hsp_hseq>MARTITFDIP-SQYKLVDLIGEGAYGTVCSAIHK-PS--GIKVAIKKIQPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLAR</Hsp_hseq>
      <Hsp_midline>M  T  ++IP  + +LV  IGEG +G V   I+K PS   + VA+K  +         + ++E   +R F +H +I+ ++  +    I      ++V EL +           S   TL    +  + YQ+  AL  + S +++HRDI   N+L++S   +K+ DFGL+R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>6.37544e-09</Hsp_evalue>
      <Hsp_query-from>1098</Hsp_query-from>
      <Hsp_query-to>1592</Hsp_query-to>
      <Hsp_hit-from>11</Hsp_hit-from>
      <Hsp_hit-to>196</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>187</Hsp_align-len>
      <Hsp_qseq>YAEIVDD-EDTYNMPSTRDYEIPRDEVE-----LVTCIGEGQFGDVHKGIYKSPSDP-----NMP--VAVKTCK-ESCSDSVRE--KFLQEAYTMRQFDHPHIVKLIGVISDPP-IWIVMELCKYGESNCYT-----LDLGTLILYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGL</Hsp_qseq>
      <Hsp_hseq>YGGFTNDLSDTFQYPQRTD-EQRRKHVTFGPYILGSTLGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRKEVKIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGF</Hsp_hseq>
      <Hsp_midline>Y    +D  DT+  P   D E  R  V      L + +GEG+FG V  G  K+ S+      + P  VA+K  K +S S+  R+  K  +E   ++   HP+IVKL  V+ +   I IV+E    GE   Y      L          QL + + Y+ SK +VHRD+   N+L+   + + + DFG </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>6.93156e-09</Hsp_evalue>
      <Hsp_query-from>1170</Hsp_query-from>
      <Hsp_query-to>1604</Hsp_query-to>
      <Hsp_hit-from>14</Hsp_hit-from>
      <Hsp_hit-to>167</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>EVELVTCIGEGQFGDVHKGIYKSPSDPNMPVAVK-----TCKE---SCSDSVREKFLQEAYTMRQFDHPHIVKLIGV-ISDPPIWIVMELCKYGE-----SNCYTLDLGTLILYIYQLSTALSYLESK-KIVHRDIAARNVLVSSADCVKLADFGLSRHM</Hsp_qseq>
      <Hsp_hseq>DVVLGDTVGQGAFACVKNAHLQM--DPSIILAVKFIHVPTCKKMGLSDKDITKEVVLQSKCS----KHPNVLRLIDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGLASQF</Hsp_hseq>
      <Hsp_midline>+V L   +G+G F  V     +   DP++ +AVK     TCK+   S  D  +E  LQ   +     HP++++LI   +S   +WI++E+   G+          +D      Y  QL +A++YL  +  + HRDI   N+L+     +KLADFGL+   </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>7.86206e-09</Hsp_evalue>
      <Hsp_query-from>1191</Hsp_query-from>
      <Hsp_query-to>1640</Hsp_query-to>
      <Hsp_hit-from>1181</Hsp_hit-from>
      <Hsp_hit-to>1345</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>IGEGQFGDVHKGIYKSPSDPNMPVAVKTCKESCSD----SVREKFLQEAYTMRQFDHPHIVKLIGVISDPPIW-IVMELCKYGESNCYTLDLGTLI-LY-------IYQLST----ALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSRHMED-----DTYYKGVCMW</Hsp_qseq>
      <Hsp_hseq>IGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLEYVAGGS-------VGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFW</Hsp_hseq>
      <Hsp_midline>IG+G FG V+  +  +  +      V+  K S  +    S  E    E  T++  DH +IV+ +G  +   I+ + +E    G        +G+LI +Y       I  L+T     L+YL SK I+HRD+ A N+L+      K++DFG+SR  +D     D   +G   W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>8.62035e-09</Hsp_evalue>
      <Hsp_query-from>1071</Hsp_query-from>
      <Hsp_query-to>1592</Hsp_query-to>
      <Hsp_hit-from>331</Hsp_hit-from>
      <Hsp_hit-to>528</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>206</Hsp_align-len>
      <Hsp_qseq>LRQLKDTDDYAEIVDDEDTYNMPSTRDYEIPRDEVELVTCIGEGQFGDVHKGIYKSPSDPNMPVAVKT-CKESCSDSV------------REKFLQEAYTMRQFDHPHIVKLIG--VISDPPIWIVMELCKYGESNCYT-----------------LDLGTLILYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGL</Hsp_qseq>
      <Hsp_hseq>LLELKNNDDSNEIIMKMKTVAIDVN-----PRPYFQLVEKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQPKKQLIMNELLVMNDSRQENIVNFLEAYIIDDEELWVIME---YMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGF</Hsp_hseq>
      <Hsp_midline>L +LK+ DD  EI+    T  +        PR   +LV   G+G  G V+          N P  +K+ C     + V            ++  + E   M      +IV  +   +I D  +W++ME   Y E  C T                 L+   +   + +    L +L +KKI+HRDI + N+L++S   VK+ DFG </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>1.02392e-08</Hsp_evalue>
      <Hsp_query-from>1170</Hsp_query-from>
      <Hsp_query-to>1619</Hsp_query-to>
      <Hsp_hit-from>86</Hsp_hit-from>
      <Hsp_hit-to>240</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>158</Hsp_align-len>
      <Hsp_qseq>EVELVTCIGEGQFGDVHKGIYKSPSDPNMPVAVKTCKESCSDSVR--EKFLQEAYTMRQFDHPHIVKLIGVISDPP-IWIVMELCKYGE-----SNCYTLDLGTLILYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSRHMEDDTY</Hsp_qseq>
      <Hsp_hseq>DFQILRTLGTGSFGRVH--LIRSRHNGRY-YAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTY</Hsp_hseq>
      <Hsp_midline>+ +++  +G G FG VH  + +S  +     A+K  K+     ++  E    E   +    HP I+++ G   D   I+++M+  + GE                  Y  ++  AL YL SK I++RD+   N+L+     +K+ DFG ++++ D TY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>1.15207e-08</Hsp_evalue>
      <Hsp_query-from>1317</Hsp_query-from>
      <Hsp_query-to>1595</Hsp_query-to>
      <Hsp_hit-from>103</Hsp_hit-from>
      <Hsp_hit-to>211</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>109</Hsp_align-len>
      <Hsp_qseq>QEAYTMRQFDHPHIVKLIGVISDP---PIWIVMELCKYG------ESNCYTLDLGTLILYIYQ-------LSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLS</Hsp_qseq>
      <Hsp_hseq>QEIEVMKRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVA</Hsp_hseq>
      <Hsp_midline>QE   M++  H ++V+L  +++DP    +++V+E C  G      E+      +G  IL   Q       + + L YL S+ I HRDI   N+L+SS   VK++DFG++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>2.22571e-08</Hsp_evalue>
      <Hsp_query-from>1305</Hsp_query-from>
      <Hsp_query-to>1874</Hsp_query-to>
      <Hsp_hit-from>197</Hsp_hit-from>
      <Hsp_hit-to>422</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>54</Hsp_gaps>
      <Hsp_align-len>235</Hsp_align-len>
      <Hsp_qseq>EKFLQEAYTMRQFDHPHIVKLIGVISD-PPIWIVMELCKYGESNCY-----TLDLGTLILYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSRHMEDDT--------------------------------------YYKGVCMWEILMFGVKPFQGVKNNDIIGRIENGERLP-MPHNCPPTLYSIMTNDIYEDEKTQQEDRQKRDHRRIAPPWTAGGADEAP</Hsp_qseq>
      <Hsp_hseq>ERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIPFYLSEGMKDIL-NALLKKETAKRWNVDKY--------WAKTGANNKP</Hsp_hseq>
      <Hsp_midline>E+   E   + + +HP+IVKL     D   ++++++    GE   +     TLD  T+  Y  ++S AL +L +K +V+RD+   N L++    + L DFGLS+   +D+                                      +Y   C+   ++ G  P+ G  +  II +I+  ++ P +P      +  I+ N + + E  ++ +  K         W   GA+  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>3.10867e-08</Hsp_evalue>
      <Hsp_query-from>1191</Hsp_query-from>
      <Hsp_query-to>1598</Hsp_query-to>
      <Hsp_hit-from>66</Hsp_hit-from>
      <Hsp_hit-to>218</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>156</Hsp_align-len>
      <Hsp_qseq>IGEGQFGDVHKGIYKSPSDPNMPVAVKTCKESCSDSVREKFLQEAYT-MRQFDHPHIVKLIGVISD--PPI-----------------WIVMELCKYGESNCYTLDLGTLILYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSR</Hsp_qseq>
      <Hsp_hseq>LGQGTFGEVYKGIH---LETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLAR</Hsp_hseq>
      <Hsp_midline>+G+G FG+V+KGI+    +    VA+K    S    +     Q   T +++ +H +I+KLI ++ D  P I                 ++V +L     +    L++  +   + Q+   L+Y+   K +HRDI   N+L+     +KLADFGL+R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>5.38331e-08</Hsp_evalue>
      <Hsp_query-from>1191</Hsp_query-from>
      <Hsp_query-to>1592</Hsp_query-to>
      <Hsp_hit-from>626</Hsp_hit-from>
      <Hsp_hit-to>760</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>140</Hsp_align-len>
      <Hsp_qseq>IGEGQFGDVHKGIYKSPSDPNMPVAVKTCKESCSDSVREKFLQEAYTMRQFDHPHIVKLI-GVISDPPIWIVMELCKYGE-----SNCYTLDLGTLILYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGL</Hsp_qseq>
      <Hsp_hseq>IGQGASGGVYTA-YEIGT--NVSVAIKQMNLE-KQPKKELIINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVTHCI-LTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGF</Hsp_hseq>
      <Hsp_midline>IG+G  G V+   Y+  +  N+ VA+K          +E  + E   M+   HP+IV  I   +    +W++ME  + G      ++C  L  G +     +  + L +L SK ++HRDI + N+L+S    +KL DFG </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>1.17848e-07</Hsp_evalue>
      <Hsp_query-from>1176</Hsp_query-from>
      <Hsp_query-to>1598</Hsp_query-to>
      <Hsp_hit-from>39</Hsp_hit-from>
      <Hsp_hit-to>189</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>152</Hsp_align-len>
      <Hsp_qseq>ELVTCIGEGQFGDVHKGIYKSPSDPNMPVAVKTCKESCSDSVR-EKFLQEAYTMRQF-DHPHIVKLIG--VISDPP---IWIVMELCKYGES----NCYTLDLGTLILYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSR</Hsp_qseq>
      <Hsp_hseq>EIIQFLGKGAYGTVCSVKFKGRS-PAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGHKNIVNLIDLEIVTSSPYDGLYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLAR</Hsp_hseq>
      <Hsp_midline>E++  +G+G +G V    +K  S P   +AVK      +  +  ++ ++E   M  F  H +IV LI   +++  P   ++   EL  Y  +    +   L    +  ++YQ+   L Y+ S  ++HRD+   N+L +   C+K+ DFGL+R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>1.38407e-07</Hsp_evalue>
      <Hsp_query-from>1188</Hsp_query-from>
      <Hsp_query-to>1628</Hsp_query-to>
      <Hsp_hit-from>52</Hsp_hit-from>
      <Hsp_hit-to>209</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>159</Hsp_align-len>
      <Hsp_qseq>CIGEGQFGDVHKGIYKSPSDPNMPVAVKTCKESCSDSVREKFL-QEAYTMRQFDHPHIVKLIGVI-SDPPIWIVMELCKYGESNCYTLDLGTL-----ILYIYQLSTALSYLESKKIVHRDIAARNVLV---SSADCVKLADFGLSRHM--EDDTYYKG</Hsp_qseq>
      <Hsp_hseq>TLGAGSFGVVRQA-RKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKA</Hsp_hseq>
      <Hsp_midline> +G G FG V +   K  ++ ++ + +   K    ++V+ + L +E   +++  HP+IV       S    +IV +L   GE     L  G       +  I Q+  A+ Y+ SK +VHRD+   NVL    S    + +ADFG+++ +  E+D  YK </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YFL033C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:69115:74427:-1 gene:YFL033C transcript:YFL033C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM15 description:Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase [Source:SGD;Acc:S000001861]</Hit_def>
  <Hit_accession>YFL033C</Hit_accession>
  <Hit_len>1770</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>1.53041e-07</Hsp_evalue>
      <Hsp_query-from>1137</Hsp_query-from>
      <Hsp_query-to>1598</Hsp_query-to>
      <Hsp_hit-from>789</Hsp_hit-from>
      <Hsp_hit-to>941</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>170</Hsp_align-len>
      <Hsp_qseq>PSTRDYEIPRDEVELVTCIGEGQFGDVHKGIYKSPSDPNMPVAVKTCKES---CSDSVREKFLQEAYTMRQFDHPHIVKLIGVISDP-PIWIVMELCKYGESNCYTLDLGTLI------------LYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSR</Hsp_qseq>
      <Hsp_hseq>PSIKDYDI-------LKPISKGAYGSVYLARKKLTGDY---FAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDKPYVARLFASFQNKDNLFLVMEYLPGG-------DLATLIKMMGYLPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLIDNAGHVKLTDFGLSR</Hsp_hseq>
      <Hsp_midline>PS +DY+I       +  I +G +G V+    K   D     A+K  ++S     + V     + A  M Q D P++ +L     +   +++VME    G       DL TLI             Y+ ++   ++ +    I+H D+   N+L+ +A  VKL DFGLSR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>2.09041e-07</Hsp_evalue>
      <Hsp_query-from>1134</Hsp_query-from>
      <Hsp_query-to>1610</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>164</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>169</Hsp_align-len>
      <Hsp_qseq>MPSTRDYEIPRDEVELVTCIGEGQFGDVHKGIYKSPSDPNMPVAVKTCKESCSDSVREKFLQEAYTMRQFDHPHIVKLIGVISDP-------PIWIVMELCKYGESNCYTLDLGT---LILYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSRHMED</Hsp_qseq>
      <Hsp_hseq>MPKRIVYNISSD-FQLKSLLGEGAYGVVCSATHKPTGEI---VAIKKIEPFDKPLFALRTLREIKILKHFKHENIITIFN-IQRPDSFENFNEVYIIQELMQTDLHRVISTQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDE</Hsp_hseq>
      <Hsp_midline>MP    Y I  D  +L + +GEG +G V    +K   +    VA+K  +         + L+E   ++ F H +I+ +   I  P        ++I+ EL +       +  + +   +  +IYQ   A+  L    ++HRD+   N+L++S   +K+ DFGL+R +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>4.19424e-07</Hsp_evalue>
      <Hsp_query-from>1308</Hsp_query-from>
      <Hsp_query-to>1613</Hsp_query-to>
      <Hsp_hit-from>207</Hsp_hit-from>
      <Hsp_hit-to>321</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>115</Hsp_align-len>
      <Hsp_qseq>KFLQEAYTMRQFDHPHIVKLIGVISD--PPIWIVMELCKYGESNCYTLDLGTL--------ILYIYQLSTALSYLESKKIVHRDIAARNVLVSSAD-CVK--LADFGLSRHMEDD</Hsp_qseq>
      <Hsp_hseq>KFDKEARILLRLDHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSN</Hsp_hseq>
      <Hsp_midline>KF +EA  + + DHP+I+K+     D    ++I  +L   G+   Y      L        +L ++Q+  AL+YL  + IVHRD+   N+L+ + + C +  LADFG+++ +  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>4.29685e-07</Hsp_evalue>
      <Hsp_query-from>1305</Hsp_query-from>
      <Hsp_query-to>1595</Hsp_query-to>
      <Hsp_hit-from>168</Hsp_hit-from>
      <Hsp_hit-to>270</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>103</Hsp_align-len>
      <Hsp_qseq>EKFLQEAYTMRQFDHPHIVKLIGVIS-DPPIWIVMELCKYGESNCYTLDLGTLI-----LYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLS</Hsp_qseq>
      <Hsp_hseq>KRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLS</Hsp_hseq>
      <Hsp_midline>++ ++EA   +   HPHI +L  + +     +++ E    G+   Y +  G+L       +   +++AL YL +  IVHRD+   N+++SS+  +K+ DFGLS</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>5.43693e-07</Hsp_evalue>
      <Hsp_query-from>1092</Hsp_query-from>
      <Hsp_query-to>1604</Hsp_query-to>
      <Hsp_hit-from>391</Hsp_hit-from>
      <Hsp_hit-to>604</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>217</Hsp_align-len>
      <Hsp_qseq>DDYAEIVDDEDTYNMPSTRDYEIPRDEVELVTCIGEGQFGDVHKGIYKSPS-----------DPNMPVAVKTCKESCSD-------------------------SVREKFL----QEAYTMRQFDHPHIVKLIGVISDPP-IWIVMELCKYGESNCYTLDLG----TLIL-YIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSRHM</Hsp_qseq>
      <Hsp_hseq>EDHDFFGEDSDIVSLPT--KIATPKNWLK-GACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKL</Hsp_hseq>
      <Hsp_midline>+D+    +D D  ++P+      P++ ++   CIG G FG V+ G+                + N+ V     K++ SD                         ++  K +     E   +++  H +IV   G   +   + I +E    G  +    + G    +LI  +  Q+   ++YL  K I+HRDI   N+L+    CVK+ DFG+S+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>6.69815e-07</Hsp_evalue>
      <Hsp_query-from>1143</Hsp_query-from>
      <Hsp_query-to>1634</Hsp_query-to>
      <Hsp_hit-from>337</Hsp_hit-from>
      <Hsp_hit-to>506</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>173</Hsp_align-len>
      <Hsp_qseq>TRDYEIPRDEVELVTCIGEGQFGDVHKGIYKSPSDPNMPVAVKTCKES--CSDSVREKFLQEAYTMRQFDHPHIVKLIGVISDP-PIWIVMELCKYGESNCYT-----LDLGTLILYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSR-HMEDDTYYKGVC</Hsp_qseq>
      <Hsp_hseq>SRNKPLSIDDFDLLKVIGKGSFGKVMQVRKK---DTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFC</Hsp_hseq>
      <Hsp_midline>+R+  +  D+ +L+  IG+G FG V +   K   D     A+K  ++S   S S     L E   + + D P IV L      P  ++ V+     GE   +       DL     Y  +L  AL  L    +V+RD+   N+L+     + L DFGL + +M+DD      C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>8.81608e-07</Hsp_evalue>
      <Hsp_query-from>1317</Hsp_query-from>
      <Hsp_query-to>1595</Hsp_query-to>
      <Hsp_hit-from>80</Hsp_hit-from>
      <Hsp_hit-to>178</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>99</Hsp_align-len>
      <Hsp_qseq>QEAYTMRQFDHPHIVKLIGVI-SDPPIWIVMELCKYGESNCYTLDLGTL-----ILYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLS</Hsp_qseq>
      <Hsp_hseq>REIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMA</Hsp_hseq>
      <Hsp_midline>+E   M+  +HP++++L  V  ++  +++V+E  + GE     ++ G L     I +  Q+   +SY  +  IVHRD+   N+L+     +K+ADFG++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>1.08177e-06</Hsp_evalue>
      <Hsp_query-from>1305</Hsp_query-from>
      <Hsp_query-to>1922</Hsp_query-to>
      <Hsp_hit-from>189</Hsp_hit-from>
      <Hsp_hit-to>422</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>241</Hsp_align-len>
      <Hsp_qseq>EKFLQEAYTMRQFDHPHIVKLIGVIS-DPPIWIVMELCKYGESNCYTLDLGTLI-----LYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSR--------HM---------------------EDDTYYKGVCMWEILMFGVKPFQGVKNNDIIGRIENGERLPMPHNCPPTLYSIMTNDIYEDEKTQQEDRQKRDHRRIAPPWTAGGADEAPPKHARRVMELEQALLE</Hsp_qseq>
      <Hsp_hseq>KRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLF-VLVCGKVPFDDENSSVLHEKIKQG-KVEYPQHLSIEVISLLSKMLVVDPKRRATLKQVVEHH-----WMVRGFNGPPPSYLPKRVPLTIEMLD</Hsp_hseq>
      <Hsp_midline>++ ++EA   +   HPHI +L  + +     +++ E    G+   Y +  G++       +   +++AL YL +  IVHRD+   N+++S +  +K+ DFGLS         H                      E D +  GV ++ +L+ G  PF    ++ +  +I+ G ++  P +    + S+++  +  D K +   +Q  +H      W   G +  PP +  + + L   +L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>1.24959e-06</Hsp_evalue>
      <Hsp_query-from>1191</Hsp_query-from>
      <Hsp_query-to>1613</Hsp_query-to>
      <Hsp_hit-from>41</Hsp_hit-from>
      <Hsp_hit-to>193</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>IGEGQFGDVHKGIYKSPSDPNM--PVAVKTCKESCSDSVREKFLQEAYTMRQFDHPHIVKLIGVIS--DP--------------PIWIVMELCKYGESNCYTLDLGTLILYIYQLSTALSYLESKKIVHRDIAARNVLVS-SADCVKLADFGLSRHMEDD</Hsp_qseq>
      <Hsp_hseq>IGRGAFGTVVQA-YLTQDKKNWLGPFAIKKVPAHTEYKSRE--LQ---ILRIADHPNIVKLQYFFTHLSPQDNKVYQHLAMECLPETLQIEINRY-VTNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHN</Hsp_hseq>
      <Hsp_midline>IG G FG V +  Y +    N   P A+K          RE  LQ    +R  DHP+IVKL    +   P              P  + +E+ +Y  +N   + L  + LY YQ++  + YL    + HRDI   NVLV      +K+ DFG ++ +E +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>1.30061e-06</Hsp_evalue>
      <Hsp_query-from>1170</Hsp_query-from>
      <Hsp_query-to>1619</Hsp_query-to>
      <Hsp_hit-from>69</Hsp_hit-from>
      <Hsp_hit-to>223</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>158</Hsp_align-len>
      <Hsp_qseq>EVELVTCIGEGQFGDVHKGIYKSPSDPNMPVAVKTCKESCSDSVR--EKFLQEAYTMRQFDHPHIVKLIGVISDP-PIWIVMELCKYGE-----SNCYTLDLGTLILYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSRHMEDDTY</Hsp_qseq>
      <Hsp_hseq>DFQIMRTLGTGSFGRVH--LVRSVHNGRY-YAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTW</Hsp_hseq>
      <Hsp_midline>+ +++  +G G FG VH  + +S  +     A+K  K+     ++  E    E   ++  +HP ++++ G   D   I++VM+  + GE                  Y  ++  AL YL +  I++RD+   N+L+     +K+ DFG ++ ++  T+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>2.66247e-06</Hsp_evalue>
      <Hsp_query-from>1317</Hsp_query-from>
      <Hsp_query-to>1634</Hsp_query-to>
      <Hsp_hit-from>76</Hsp_hit-from>
      <Hsp_hit-to>187</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>112</Hsp_align-len>
      <Hsp_qseq>QEAYTMRQFDHPHIVKLIGVI-SDPPIWIVMELCKYGESNCYTLDLGTL-----ILYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSRHMEDDTYYKGVC</Hsp_qseq>
      <Hsp_hseq>REIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSC</Hsp_hseq>
      <Hsp_midline>+E   M+   HP+++ L  V  ++  +++++E  + GE     +D G L     I    Q+   +SY  +  IVHRD+   N+L+ S   +K+ADFG++    D    +  C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>2.90618e-06</Hsp_evalue>
      <Hsp_query-from>1122</Hsp_query-from>
      <Hsp_query-to>1604</Hsp_query-to>
      <Hsp_hit-from>346</Hsp_hit-from>
      <Hsp_hit-to>511</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>DTYNMPSTRDYEIPRDEVELVTCIGEGQFGDVHKGIYKSPSDPNMPVAVKTCKESCSDSVREKFLQEAYTMRQFDHPHIVKLIGV-ISDPPIWIVMELCKYG--------ESNCYTLDLGTLILYIYQLSTALSYL-ESKKIVHRDIAARNVLVSS-ADCVKLADFGLSRHM</Hsp_qseq>
      <Hsp_hseq>DFSNGSSSR---ITLDELEFLDELGHGNYGNVSKVLHK-PT--NVIMATKEVRLELDEAKFRQILMELEVLHKCNSPYIVDFYGAFFIEGAVYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSANQGTVKLCDFGVSGNL</Hsp_hseq>
      <Hsp_midline>D  N  S+R   I  DE+E +  +G G +G+V K ++K P+  N+ +A K  +    ++   + L E   + + + P+IV   G    +  +++ ME    G         S    +D   L      +   L  L E   I+HRD+   N+L S+    VKL DFG+S ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>4.23611e-06</Hsp_evalue>
      <Hsp_query-from>1182</Hsp_query-from>
      <Hsp_query-to>1619</Hsp_query-to>
      <Hsp_hit-from>447</Hsp_hit-from>
      <Hsp_hit-to>611</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>168</Hsp_align-len>
      <Hsp_qseq>VTCIGEGQFGDVHKGIYKSPSDPNMPVAVKTCKESCSDSVRE-----KFLQEA---YTMRQFDHPHIVKLIGVIS-DPPIWIVMELCKYGESNCYT----------LDLGTLILYIYQLSTALSYL-ESKKIVHRDIAARNVLVSSADCVKLADFGLSRH--MEDDTY</Hsp_qseq>
      <Hsp_hseq>VHSIGKGQFSTVYQVTF---AQTNKKYAIKAIKPNKYNSLKRILLEIKILNEVTNQITMDQEGKEYIIDYISSWKFQNSYYIMTELCENGNLDGFLQEQVIAKKKRLEDWRIWKIIVELSLALRFIHDSCHIVHLDLKPANVMITFEGNLKLGDFGMATHLPLEDKSF</Hsp_hseq>
      <Hsp_midline>V  IG+GQF  V++  +   +  N   A+K  K +  +S++      K L E     TM Q    +I+  I         +I+ ELC+ G  + +           L+   +   I +LS AL ++ +S  IVH D+   NV+++    +KL DFG++ H  +ED ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>5.37766e-06</Hsp_evalue>
      <Hsp_query-from>1191</Hsp_query-from>
      <Hsp_query-to>1676</Hsp_query-to>
      <Hsp_hit-from>1102</Hsp_hit-from>
      <Hsp_hit-to>1282</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>186</Hsp_align-len>
      <Hsp_qseq>IGEGQFGDVHKGIYKSPSDPNMPVAVKTCKES--CSDSVREKFL-------QEAYTMRQFDHPHIVKLIGVISDPPIWIVMELCKYGESNCYTLDLGTLI------------LYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSRHMED---DTYYKGVCMWEILMFGVKPFQG</Hsp_qseq>
      <Hsp_hseq>MGEGAYGKVNLCIHKK--NRYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKKPHENILRLLDFFEDDDYYYI-ETPVHGETGC--IDLFDLIEFKTNMTEFEAKLIFKQVVAGIKHLHDQGIVHRDIKDENVIVDSKGFVKIIDFGSAAYVKSGPFDVFVGTIDYAAPEVLGGNPYEG</Hsp_hseq>
      <Hsp_midline>+GEG +G V+  I+K   +  + V     KE       VR++ L       Q   T+ +  H +I++L+    D   + + E   +GE+ C  +DL  LI            L   Q+   + +L  + IVHRDI   NV+V S   VK+ DFG + +++    D +   +      + G  P++G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>6.64169e-06</Hsp_evalue>
      <Hsp_query-from>1302</Hsp_query-from>
      <Hsp_query-to>1610</Hsp_query-to>
      <Hsp_hit-from>604</Hsp_hit-from>
      <Hsp_hit-to>720</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>53</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>117</Hsp_align-len>
      <Hsp_qseq>REKFLQEAYTMRQFDHPHIVKLIGVI--SDPPIWIVMELCKYG-----------ESNCYTLDLGTLILYIYQLS-TALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLSRHMED</Hsp_qseq>
      <Hsp_hseq>KELIVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTD</Hsp_hseq>
      <Hsp_midline>+E  + E   M+   H +IV  +     +D  +W+VME  + G             N ++      I YI + +   L +L  K I+HRDI + NVL+ +   VK+ DFG    + D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YPR111W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:747306:749000:1 gene:YPR111W transcript:YPR111W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF20 description:Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006315]</Hit_def>
  <Hit_accession>YPR111W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>9.39112e-06</Hsp_evalue>
      <Hsp_query-from>1170</Hsp_query-from>
      <Hsp_query-to>1595</Hsp_query-to>
      <Hsp_hit-from>168</Hsp_hit-from>
      <Hsp_hit-to>314</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>150</Hsp_align-len>
      <Hsp_qseq>EVELVTCIGEGQFGDVHKGIYKSPSDPNMPVAVKTCKESCSDSVRE--KFLQEAYTMRQFDHPHIVKLIGVISDP-PIWIVMELCKYGES-----NCYTLDLGTLILYIYQLSTALSYLESKKIVHRDIAARNVLVSSADCVKLADFGLS</Hsp_qseq>
      <Hsp_hseq>DFQILTQVGQGGYGQVYLAKKK---DSDEICALKILNKKLLFKLNETNHVLTERDILTTTRSDWLVKLLYAFQDPESLYLAMEFVPGGDFRTLLINTRILKSGHARFYISEMFCAVNALHELGYTHRDLKPENFLIDATGHIKLTDFGLA</Hsp_hseq>
      <Hsp_midline>+ +++T +G+G +G V+    K   D +   A+K   +     + E    L E   +       +VKL+    DP  +++ ME    G+      N   L  G    YI ++  A++ L      HRD+   N L+ +   +KL DFGL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2416027025</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0016859-RA transcript Note:&quot;Similar to Slc45a4 Solute carrier family 45 member 4 (Mus musculus)&quot; offset:0 AED:0.74 eAED:0.74 QI:0|0|0|0.66|1|1|3|0|356</Iteration_query-def>
  <Iteration_query-len>1071</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>615382222</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0041064-RA transcript Note:&quot;Similar to SLC45A4 Solute carrier family 45 member 4 (Homo sapiens)&quot; offset:38 AED:0.22 eAED:0.29 QI:38|0|0|0.8|0.5|0.6|5|0|675</Iteration_query-def>
  <Iteration_query-len>2066</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1350036464</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

