<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0054863-RA transcript Note:&quot;Similar to Son Protein SON (Mus musculus)&quot; offset:0 AED:0.09 eAED:0.09 QI:0|0|0|0.5|1|1|2|0|334</BlastOutput_query-def>
  <BlastOutput_query-len>1005</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054863-RA transcript Note:&quot;Similar to Son Protein SON (Mus musculus)&quot; offset:0 AED:0.09 eAED:0.09 QI:0|0|0|0.5|1|1|2|0|334</Iteration_query-def>
  <Iteration_query-len>1005</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>568416415</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054865-RA transcript Note:&quot;Similar to RAD52 DNA repair protein RAD52 homolog (Gallus gallus)&quot; offset:896 AED:0.17 eAED:0.17 QI:896|0.81|0.83|1|0.81|0.83|12|378|455</Iteration_query-def>
  <Iteration_query-len>2642</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YML032C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:212515:213930:-1 gene:YML032C transcript:YML032C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD52 description:Protein that stimulates strand exchange; stimulates strand exchange by facilitating Rad51p binding to single-stranded DNA; anneals complementary single-stranded DNA; involved in the repair of double-strand breaks in DNA during vegetative growth and meiosis and UV induced sister chromatid recombination [Source:SGD;Acc:S000004494]</Hit_def>
  <Hit_accession>YML032C</Hit_accession>
  <Hit_len>471</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>166.777</Hsp_bit-score>
      <Hsp_score>421</Hsp_score>
      <Hsp_evalue>8.88748e-45</Hsp_evalue>
      <Hsp_query-from>1059</Hsp_query-from>
      <Hsp_query-to>1541</Hsp_query-to>
      <Hsp_hit-from>19</Hsp_hit-from>
      <Hsp_hit-to>178</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>161</Hsp_align-len>
      <Hsp_qseq>QAIQSALRKRLGTEYISQRQGPGGQKLNYVEGHKVVNLANAMFGFNGWSHSVSQQNIDFVDFVDGKYYVGVSCFVKVELKDGAYHEDVGYGVSEGQRSKALSLEKARKESVTDGLKRSLRSFGNCLGNCIQDKDYLKCINRLPKPPAPVYDPADIKNPKQE</Hsp_qseq>
      <Hsp_hseq>EDIQTKLDKKLGPEYISKRVGFGTSRIAYIEGWRVINLANQIFGYNGWSTEVKSVVIDFLDERQGKFSIGCTAIVRVTLTSGTYREDIGYGTVENERRKPAAFERAKKSAVTDALKRSLRGFGNALGNCLYDKDFLAKIDKVKFDP-PDFDENNLFRPTDE</Hsp_hseq>
      <Hsp_midline>+ IQ+ L K+LG EYIS+R G G  ++ Y+EG +V+NLAN +FG+NGWS  V    IDF+D   GK+ +G +  V+V L  G Y ED+GYG  E +R K  + E+A+K +VTD LKRSLR FGN LGNC+ DKD+L  I+++   P P +D  ++  P  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1773002794</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054867-RA transcript Note:&quot;Similar to Srpk2 SRSF protein kinase 2 (Mus musculus)&quot; offset:160 AED:0.23 eAED:0.35 QI:160|0.58|0.72|0.83|1|1|18|1533|985</Iteration_query-def>
  <Iteration_query-len>4651</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YMR216C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:698811:701039:-1 gene:YMR216C transcript:YMR216C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKY1 description:SR protein kinase (SRPK); involved in regulating proteins involved in mRNA metabolism and cation homeostasis; similar to human SRPK1 [Source:SGD;Acc:S000004829]</Hit_def>
  <Hit_accession>YMR216C</Hit_accession>
  <Hit_len>742</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>201.445</Hsp_bit-score>
      <Hsp_score>511</Hsp_score>
      <Hsp_evalue>4.65394e-54</Hsp_evalue>
      <Hsp_query-from>2570</Hsp_query-from>
      <Hsp_query-to>3109</Hsp_query-to>
      <Hsp_hit-from>529</Hsp_hit-from>
      <Hsp_hit-to>706</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>94</Hsp_identity>
      <Hsp_positive>126</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>180</Hsp_align-len>
      <Hsp_qseq>SSADLVVNLLDPGNAENLTIKIADLGNACWVHKHFTEDIQTRQYRAPEVLIGAGYGVAADIWSTACMAFELATGDYLFEPHSGEDYCRDEDHIALITELMGRLPRKYALSGKYSKEFFTKQGDLRHITKLKPWGLFDVLVEKYEWPLEQAAMFTDFLLPMLEVLPEKRTSAAQCLKHAWL</Hsp_qseq>
      <Hsp_hseq>SNSNVSTDINSPENL--IQIKIADLGNACWYDEHYTNSIQTREYRSPEVLLGAPWGCGADIWSTACLIFELITGDFLFEPDEGHSYTKDDDHIAQIIELLGELPSYLLRNGKYTRTFFNSRGLLRNISKLKFWPLEDVLTEKYKFSKDEAKEISDFLSPMLQLDPRKRADAGGLVNHPWL</Hsp_hseq>
      <Hsp_midline>S++++  ++  P N   + IKIADLGNACW  +H+T  IQTR+YR+PEVL+GA +G  ADIWSTAC+ FEL TGD+LFEP  G  Y +D+DHIA I EL+G LP     +GKY++ FF  +G LR+I+KLK W L DVL EKY++  ++A   +DFL PML++ P KR  A   + H WL</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>167.548</Hsp_bit-score>
      <Hsp_score>423</Hsp_score>
      <Hsp_evalue>6.1312e-43</Hsp_evalue>
      <Hsp_query-from>1316</Hsp_query-from>
      <Hsp_query-to>1798</Hsp_query-to>
      <Hsp_hit-from>143</Hsp_hit-from>
      <Hsp_hit-to>307</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>85</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>165</Hsp_align-len>
      <Hsp_qseq>GYHPVKIGDLF-NGRYHVVRKLGWGHFSTVWLCWDMQVKWFVALKVVKSAPHYTETALDEIKLLKCVRDGDPKDPNR---EKVVQLVDDFKVSGVNGLHVCMVFEVLGHQLLKWIIKSNYKGLPLPCVKSIIQQVLQGLDYLHTKCKIIHTDIKPENILLCVDDA</Hsp_qseq>
      <Hsp_hseq>GYHPAFKGEPYKDARYILVRKLGWGHFSTVWLAKDMVNNTHVAMKIVRGDKVYTEAAEDEIKLLQRVNDADNTKEDSMGANHILKLLDHFNHKGPNGVHVVMVFEVLGENLLALIKKYEHRGIPLIYVKQISKQLLLGLDYMHRRCGIIHTDIKPENVLMEIGDV</Hsp_hseq>
      <Hsp_midline>GYHP   G+ + + RY +VRKLGWGHFSTVWL  DM     VA+K+V+    YTE A DEIKLL+ V D D    +      +++L+D F   G NG+HV MVFEVLG  LL  I K  ++G+PL  VK I +Q+L GLDY+H +C IIHTDIKPEN+L+ + D </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>91.2781</Hsp_bit-score>
      <Hsp_score>225</Hsp_score>
      <Hsp_evalue>5.59131e-19</Hsp_evalue>
      <Hsp_query-from>1349</Hsp_query-from>
      <Hsp_query-to>1795</Hsp_query-to>
      <Hsp_hit-from>366</Hsp_hit-from>
      <Hsp_hit-to>508</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>150</Hsp_align-len>
      <Hsp_qseq>NGRYHVVRKLGWGHFSTVWLCWDMQVKWFVALKVVKSAPHYTETALDEIKLLKCVRDG-DPKDPNREKVVQLVDDFKVSGVNGLHVCMVFEVLGHQLLKWIIKSNYKGLPLPCVKSIIQQVLQGLDYLHTKCKIIHTDIKPENILLCVDD</Hsp_qseq>
      <Hsp_hseq>NRKYLVLDILGQGTFGQVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILELLNQKIDPT--NKHHFLRMYDSF----VHKNHLCLVFELLSNNLYELLKQNKFHGLSIQLIRTFTTQILDSLCVLK-ESKLIHCDLKPENILLCAPD</Hsp_hseq>
      <Hsp_midline>N +Y V+  LG G F  V  C ++  K  +A+KVVKS   Y   ++ E K+L+ +    DP   N+   +++ D F    V+  H+C+VFE+L + L + + ++ + GL +  +++   Q+L  L  L  + K+IH D+KPENILLC  D</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>3.7329e-08</Hsp_evalue>
      <Hsp_query-from>2627</Hsp_query-from>
      <Hsp_query-to>2929</Hsp_query-to>
      <Hsp_hit-from>512</Hsp_hit-from>
      <Hsp_hit-to>606</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>101</Hsp_align-len>
      <Hsp_qseq>IKIADLGNACWVHKHFTEDIQTRQYRAPEVLIGAGYGVAADIWSTACMAFELATGDYLFEPHSGEDYCRDEDHIALITELMGRLPRKYALSGKYSKEFFTK</Hsp_qseq>
      <Hsp_hseq>LKIIDFGSSCEEARTVYTYIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAELFLGIPIF-PGASE-----YNQLTRIIDTLGYPPSWMIDMGKNSGKFMKK</Hsp_hseq>
      <Hsp_midline>+KI D G++C   +     IQ+R YRAPE+++G  Y  + D+WS  C+  EL  G  +F P + E      + +  I + +G  P      GK S +F  K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YLL019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:105686:107899:-1 gene:YLL019C transcript:YLL019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KNS1 description:Protein kinase involved in negative regulation of PolIII transcription; effector kinase of the TOR signaling pathway and phosphorylates Rpc53p to regulate ribosome and tRNA biosynthesis; member of the LAMMER family of protein kinases, which are serine/threonine kinases also capable of phosphorylating tyrosine residues; capable of autophosphorylation [Source:SGD;Acc:S000003942]</Hit_def>
  <Hit_accession>YLL019C</Hit_accession>
  <Hit_len>737</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.8037</Hsp_bit-score>
      <Hsp_score>203</Hsp_score>
      <Hsp_evalue>2.53042e-16</Hsp_evalue>
      <Hsp_query-from>1316</Hsp_query-from>
      <Hsp_query-to>1831</Hsp_query-to>
      <Hsp_hit-from>297</Hsp_hit-from>
      <Hsp_hit-to>464</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>175</Hsp_align-len>
      <Hsp_qseq>GYHPVKIGDLFN--GRYHVVRKLGWGHFSTVWLCWDMQVK-WFVALKVVKSAPHYTETALDEIKLLKCVRDGDPKDPNREKVVQLVDDFKVSGVNGLHVCMVFEVLGHQLLKWIIKSNYKGLPLPCVKSIIQQVLQGLDYLHTKCKIIHTDIKPENILLCVDDAYVRRLAAEATQ</Hsp_qseq>
      <Hsp_hseq>GHYVYQENDIFGSGGRFVVKDLLGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDRYREAAKTELRILQTILNNDPQGQFQCLLLRECFDYKN------HICLVTDLYGRSIYDFMCSNGIARFPGSHIQAIARQLIRSVCFLH-DLGIIHTDLKPENILICDETHIAQKLPLKTVQ</Hsp_hseq>
      <Hsp_midline>G++  +  D+F   GR+ V   LG G F  V  C D + +  +VA+KV+++   Y E A  E+++L+ + + DP+   +  +++   D+K       H+C+V ++ G  +  ++  +     P   +++I +Q+++ + +LH    IIHTD+KPENIL+C +    ++L  +  Q</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>2.04017e-10</Hsp_evalue>
      <Hsp_query-from>2615</Hsp_query-from>
      <Hsp_query-to>2872</Hsp_query-to>
      <Hsp_hit-from>482</Hsp_hit-from>
      <Hsp_hit-to>561</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>86</Hsp_align-len>
      <Hsp_qseq>ENLTIKIADLGNACWVHKHFTEDIQTRQYRAPEVLIGAGYGVAADIWSTACMAFELATGDYLFEPHSGEDYCRDEDHIALITELMG</Hsp_qseq>
      <Hsp_hseq>KNPEIKIIDFGSAIFHYEYHPPVISTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVIGESLYPIHE------NLEHMAMMQRING</Hsp_hseq>
      <Hsp_midline>+N  IKI D G+A + +++    I TR YRAPE+++G G+    DIWS AC+  EL  G+ L+  H       + +H+A++  + G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>2.91775e-10</Hsp_evalue>
      <Hsp_query-from>2672</Hsp_query-from>
      <Hsp_query-to>3112</Hsp_query-to>
      <Hsp_hit-from>165</Hsp_hit-from>
      <Hsp_hit-to>298</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>159</Hsp_align-len>
      <Hsp_qseq>FTEDIQTRQYRAPEVLIGA-GYGVAADIWSTACMAFELATGDYLFEPHSGEDYCRDEDHIALITELMG-----------RLPRKYALSGKYSKEFFTKQGDLRHITKLKPWGLFDVLVEKYEWPLEQAAMFTDFLLPMLEVLPEKRTSAAQCLKHAWLG</Hsp_qseq>
      <Hsp_hseq>FSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPG------TNDEEQLKLIFDIMGTPNESLWPSVTKLP-------KYNP----------NIQQRPPRDLRQVLQPHTKEPLDGNLM--DFLHGLLQLNPDMRLSAKQALHHPWFA</Hsp_hseq>
      <Hsp_midline>F+ ++ T  YRAP+VL+G+  Y  + DIWS  C+  E+ TG  LF          DE+ + LI ++MG           +LP       KY+           +I +  P  L  VL    + PL+   M  DFL  +L++ P+ R SA Q L H W  </Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>2.94425e-10</Hsp_evalue>
      <Hsp_query-from>1349</Hsp_query-from>
      <Hsp_query-to>1783</Hsp_query-to>
      <Hsp_hit-from>4</Hsp_hit-from>
      <Hsp_hit-to>141</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>151</Hsp_align-len>
      <Hsp_qseq>NGRYHVVRKLGWGHFSTVWLCWDMQVKWFVALKVVK--SAPHYTETALDEIKLLKCVRDGDPKDPNREKVVQLVDDFKVSGVNGLHVCMVFEVLGHQLLKWI----IKSNYKGLPLPCVKSIIQQVLQGLDYLHTKCKIIHTDIKPENILL</Hsp_qseq>
      <Hsp_hseq>SSQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELK--------HENIVRLYDVIHTEN----KLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCH-ENKILHRDLKPQNLLI</Hsp_hseq>
      <Hsp_midline>+ ++  + KLG G ++TV+   +     +VALK VK  S      TA+ EI L+K ++         E +V+L D           + +VFE + + L K++    + +  +GL L  VK    Q+LQGL + H + KI+H D+KP+N+L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>3.23538e-09</Hsp_evalue>
      <Hsp_query-from>2573</Hsp_query-from>
      <Hsp_query-to>3106</Hsp_query-to>
      <Hsp_hit-from>137</Hsp_hit-from>
      <Hsp_hit-to>301</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>182</Hsp_align-len>
      <Hsp_qseq>SADLVVNLLDPGNA---ENLTIKIADLGNACWVHKHFTEDIQTRQYRAPEVLIG-AGYGVAADIWSTACMAFELATGDYLFEPHSGEDYCRDEDHIALITELMGRLPRKYALSGKYSKEFFTKQGDLRHITKLKPWGLFDVLVEKYEWPLEQAAMFTDFLLPMLEVLPEKRTSAAQCLKHAW</Hsp_qseq>
      <Hsp_hseq>SAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLF---PGKDHVH---QFSIITDLLGSPPKDVINT-------ICSENTLKFVTSL-PHRDPIPFSERFK-TVEPDAV--DLLEKMLVFDPKKRITAADALAHPY</Hsp_hseq>
      <Hsp_midline>SA ++   L P N    EN  +KI D G A       T  + TR YRAPE+++    Y V  DIWS  C+  E+  G  LF    G+D+       ++IT+L+G  P+    +          +  L+ +T L P        E+++  +E  A+  D L  ML   P+KR +AA  L H +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.5362</Hsp_bit-score>
      <Hsp_score>140</Hsp_score>
      <Hsp_evalue>6.0066e-09</Hsp_evalue>
      <Hsp_query-from>1352</Hsp_query-from>
      <Hsp_query-to>1783</Hsp_query-to>
      <Hsp_hit-from>53</Hsp_hit-from>
      <Hsp_hit-to>185</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>148</Hsp_align-len>
      <Hsp_qseq>GRYHVVRKLGWGHFSTVWLCWDMQVKWFVALKVVKS---APHYTETALD-EIKLLKCVRDGDPKDPNREKVVQLVDDFKVSGVNGLHVCMVFEVLGHQLLKWIIKSNYKGLPLPCVKSIIQQVLQGLDYLHTKCKIIHTDIKPENILL</Hsp_qseq>
      <Hsp_hseq>GNYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLR--------HPHIIKLYDVIKSKD----EIIMVIEYAGNELFDYIVQRD--KMSEQEARRFFQQIISAVEYCH-RHKIVHRDLKPENLLL</Hsp_hseq>
      <Hsp_midline>G Y +V+ LG G F  V L +       VALK++     A    +  ++ EI  L+ +R           +++L D  K        + MV E  G++L  +I++ +   +     +   QQ++  ++Y H + KI+H D+KPEN+LL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>6.92198e-09</Hsp_evalue>
      <Hsp_query-from>1319</Hsp_query-from>
      <Hsp_query-to>1792</Hsp_query-to>
      <Hsp_hit-from>121</Hsp_hit-from>
      <Hsp_hit-to>288</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>175</Hsp_align-len>
      <Hsp_qseq>YHPVKIGDLFNGRYHVVRKLGWGHFSTVWLCWDMQVKWFVALKVVKSAPHYTETALDEIKLLKCVRDGDPKDP-------NREKVVQLV---DDFKVSGVNGLHVCMVFEVLGHQLLKWI----IKSNYKG---LPLPCVKSIIQQVLQGLDYLHTKCKIIHTDIKPENILLCVD</Hsp_qseq>
      <Hsp_hseq>YDPVSKRKVLNT-YEIIKELGHGQHGKVKLARDILSKQLVAIKIVDRHEKKQRKFFTFIKSSKISENDKIKREIAIMKKCHHKHVVQLIEVLDDLK-----SRKIYLVLEYCSRGEVKWCPPDCMESDAKGPSLLSFQETREILRGVVLGLEYLHYQG-IIHRDIKPANLLISGD</Hsp_hseq>
      <Hsp_midline>Y PV    + N  Y ++++LG G    V L  D+  K  VA+K+V             IK  K   +   K         + + VVQL+   DD K        + +V E      +KW     ++S+ KG   L     + I++ V+ GL+YLH +  IIH DIKP N+L+  D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>1.27793e-08</Hsp_evalue>
      <Hsp_query-from>2573</Hsp_query-from>
      <Hsp_query-to>3130</Hsp_query-to>
      <Hsp_hit-from>146</Hsp_hit-from>
      <Hsp_hit-to>325</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>199</Hsp_align-len>
      <Hsp_qseq>SADLVVNLLDPGN---AENLTIKIADLG-------NACWVHKHFTEDIQTRQYRAPEVLIG-AGYGVAADIWSTACMAFELATGDYLFEPHSGEDYCRDEDHIALITELMGRLPRK--YALSGKYSKEFFTKQGDLRHITKLKPWGLFDVLVEKYEWPLEQAAMFTDFLLPMLEVLPEKRTSAAQCLKHAWLGC*RRPA</Hsp_qseq>
      <Hsp_hseq>SADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFK---GKDYV---NQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVP----------FVNLYPNANSQA---LDLLEQMLAFDPQKRITVDEALEHPYLSIWHDPA</Hsp_hseq>
      <Hsp_midline>SAD++   L PGN     +  +KI D G       N     +  TE + TR YRAPE+++   GY  A D+WS  C+  E   G  +F+   G+DY    + +  I +++G  P +    +  K  +++  + G +  +            V  Y     QA    D L  ML   P+KR +  + L+H +L     PA</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>3.99935e-08</Hsp_evalue>
      <Hsp_query-from>1355</Hsp_query-from>
      <Hsp_query-to>1810</Hsp_query-to>
      <Hsp_hit-from>37</Hsp_hit-from>
      <Hsp_hit-to>210</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>184</Hsp_align-len>
      <Hsp_qseq>RYHVVRKLGWGHFSTVWLC------------------------------WDMQVKWFVALKVVKSAPHYTE--TALDEIKLLKCVRDGDPKDPNREKVVQLVDDFKVSGVNGLHVCMVFEVLGHQLLKWIIKSNYKGLPLPCVKSIIQQVLQGLDYLHTKCKIIHTDIKPENILLCVDDAYVRR</Hsp_qseq>
      <Hsp_hseq>RYQLIEKLGAGSFGCVTLAKAQFPLSNILGKQHDIRGTLMDQPKNGHQNYITKTQGVVAIKTMMTKLHTLQDYTRVREIKFILAI-------PANDHLIQIFEVFIDSENYQLHIVM--ECMEQNLYQMMKHRRRRVFSIPSLKSILSQILAGLKHIH-EHNFFHRDLKPENILITPSTQYFEK</Hsp_hseq>
      <Hsp_midline>RY ++ KLG G F  V L                               +  + +  VA+K + +  H  +  T + EIK +  +       P  + ++Q+ + F  S    LH+ M  E +   L + +     +   +P +KSI+ Q+L GL ++H +    H D+KPENIL+     Y  +</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>8.42921e-06</Hsp_evalue>
      <Hsp_query-from>2606</Hsp_query-from>
      <Hsp_query-to>2872</Hsp_query-to>
      <Hsp_hit-from>217</Hsp_hit-from>
      <Hsp_hit-to>302</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>92</Hsp_align-len>
      <Hsp_qseq>GNAENLTIKIADLGNACWVHKH--FTEDIQTRQYRAPEVLIGAG-YGVAADIWSTACMAFELATGDYLFEPHSGEDYCRDEDHIALITELMG</Hsp_qseq>
      <Hsp_hseq>GYQDNYVIKLADFGLARHVENKNPYTAYVSTRWYRSPEILLRSGYYSKPLDIWAFGCVAVEVTVFRALF-PGANE-----IDQIWKILEVLG</Hsp_hseq>
      <Hsp_midline>G  +N  IK+AD G A  V     +T  + TR YR+PE+L+ +G Y    DIW+  C+A E+     LF P + E      D I  I E++G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>8.39302e-08</Hsp_evalue>
      <Hsp_query-from>2573</Hsp_query-from>
      <Hsp_query-to>3130</Hsp_query-to>
      <Hsp_hit-from>136</Hsp_hit-from>
      <Hsp_hit-to>320</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>202</Hsp_align-len>
      <Hsp_qseq>SADLVVNLLDPGN---AENLTIKIADLGNA-CWVHK---------HFTEDIQTRQYRAPEVLIGAG-YGVAADIWSTACMAFELATGDYLFEPHSGEDYCRDEDHIALITELMG--RLPRKYALSGKYSKEFFTKQGDLRHITKLKPWGLFDVLVEKYEWPLEQAAMFTDFLLPMLEVLPEKRTSAAQCLKHAWLGC*RRPA</Hsp_qseq>
      <Hsp_hseq>SAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLF---PGRDY---HHQLWLILEVLGTPSFEDFNQIKSKRAKEYIAN-------LPMRPPLPWETVWSKTDLNPD----MIDLLDKMLQFNPDKRISAAEALRHPYLAMYHDPS</Hsp_hseq>
      <Hsp_midline>SA ++   + P N     N  +K+ D G A C               TE + TR YRAPE+++    Y  A DIWS  C+  E+ +G  LF    G DY      + LI E++G         +  K +KE+            ++P   ++ +  K +   +      D L  ML+  P+KR SAA+ L+H +L     P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YDL079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:312951:314748:-1 gene:YDL079C transcript:YDL079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRK1 description:Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication [Source:SGD;Acc:S000002237]</Hit_def>
  <Hit_accession>YDL079C</Hit_accession>
  <Hit_len>501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>5.43934e-07</Hsp_evalue>
      <Hsp_query-from>2594</Hsp_query-from>
      <Hsp_query-to>3109</Hsp_query-to>
      <Hsp_hit-from>296</Hsp_hit-from>
      <Hsp_hit-to>447</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>178</Hsp_align-len>
      <Hsp_qseq>LLDPGNAENLTIKIADLGNACWVH--KHFTEDIQTRQYRAPEVLIGA-GYGVAADIWSTACMAFELATGDYLFEPHSGEDYCRDEDHIALITELMGRLPRKYALSG---KYSKEFFTKQGDLRHITKLKPWGLFDVLVEKYEWPLEQAAMFTDFLLPMLEVLPEKRTSAAQCLKHAWL</Hsp_qseq>
      <Hsp_hseq>LVDPTT---FSFKICDFGSAKCLKPDQPNVSYICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESG------IDQLVEIIKIMG-IPTKDEISGMNPNYEDHVF---------PNIKPITLAEIF--KAEDPDT-----LDLLTKTLKYHPCERLVPLQCLLSSYF</Hsp_hseq>
      <Hsp_midline>L+DP      + KI D G+A  +   +     I +R YRAPE++ GA  Y    D+WS+AC+  EL  G  LF   SG       D +  I ++MG +P K  +SG    Y    F           +KP  L ++   K E P        D L   L+  P +R    QCL  ++ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>2.03497e-06</Hsp_evalue>
      <Hsp_query-from>1376</Hsp_query-from>
      <Hsp_query-to>1792</Hsp_query-to>
      <Hsp_hit-from>1181</Hsp_hit-from>
      <Hsp_hit-to>1314</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>141</Hsp_align-len>
      <Hsp_qseq>LGWGHFSTVWLCWDMQVKWFVALKVVKSAPHYTETALDEIKLLKCVRD--GDPKDPNREKVVQLVDDFKVSGVNGLHVCMVFEVLGHQLLKWIIKSNYKGLPLPCVKSIIQQVLQGLDYLHTKCKIIHTDIKPENILLCVD</Hsp_qseq>
      <Hsp_hseq>IGKGSFGAVYLCLNVTTGEMMAVKQVE-VPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLG---FENKNNIYSLFLEYVAGGSVGSLI--RMYGRFDEPLIKHLTTQVLKGLAYLHSKG-ILHRDMKADNLLLDQD</Hsp_hseq>
      <Hsp_midline>+G G F  V+LC ++     +A+K V+  P Y+      +  ++ +R      KD +   +VQ +        N ++   +  V G  +   I    Y     P +K +  QVL+GL YLH+K  I+H D+K +N+LL  D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>2.51257e-06</Hsp_evalue>
      <Hsp_query-from>1337</Hsp_query-from>
      <Hsp_query-to>1792</Hsp_query-to>
      <Hsp_hit-from>3</Hsp_hit-from>
      <Hsp_hit-to>147</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>GDLFNGRYHVVRKLGWGHFSTVWLCWDM---QVKWFVALKVVKSAPH---YTETALDEIKLLKCVRDGDPKDPNREKVVQLVDDFKVSGVNGLHVCMVFEVLGHQLLKWIIKSNYKGLPL--PCVKSIIQQVLQGLDYLHTKCKIIHTDIKPENILLCVD</Hsp_qseq>
      <Hsp_hseq>GELAN--YKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKD--------DNIVRLYD---IVHSDAHKLYLVFEFLDLDLKRYM-EGIPKDQPLGADIVKKFMMQLCKGIAYCHSH-RILHRDLKPQNLLINKD</Hsp_hseq>
      <Hsp_midline>G+L N  Y  + K+G G +  V+   D+   Q +  VALK ++          TA+ EI LLK ++D        + +V+L D   +   +   + +VFE L   L +++ +   K  PL    VK  + Q+ +G+ Y H+  +I+H D+KP+N+L+  D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>7.15848e-06</Hsp_evalue>
      <Hsp_query-from>1358</Hsp_query-from>
      <Hsp_query-to>1783</Hsp_query-to>
      <Hsp_hit-from>18</Hsp_hit-from>
      <Hsp_hit-to>149</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>145</Hsp_align-len>
      <Hsp_qseq>YHVVRKLGWGHFSTVWLCWDMQVKWFVALKVVKSAPHYTETALDEIKLL--KCVRDGDPKDPNREKVVQLVDDFKVSGVNGLHVCMVFEVLGHQLLKWIIKSNY-KGLPLPCVKSIIQQVLQGLDYLHTKCKIIHTDIKPENILL</Hsp_qseq>
      <Hsp_hseq>YSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVN-----LEHSDEDIELLAQEIFFLAELKSP-------LITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRK-IHRDIKAANILL</Hsp_hseq>
      <Hsp_midline>Y +   +G G+F  V+   D   +  VA+KVV       E + ++I+LL  +     + K P       L+ ++  + +  + + +V E  G      ++K +Y  GLP   V  II +V  GL YLH + K IH DIK  NILL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>9.32629e-06</Hsp_evalue>
      <Hsp_query-from>1376</Hsp_query-from>
      <Hsp_query-to>1783</Hsp_query-to>
      <Hsp_hit-from>185</Hsp_hit-from>
      <Hsp_hit-to>311</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>LGWGHFSTVWLCWDMQVKWFVALKVVKSAPHYTETALDEIKLLKCVRDGDPKDPNREKVVQLVDDFKVSGVNGLHVCMVFEVLGHQLLKWIIKSNYKGLPLPCVKSIIQQVLQGLDYLHTKCKIIHTDIKPENILL</Hsp_qseq>
      <Hsp_hseq>IGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQ---KKVKYVSIEKTALQKLNNSPSVVRLFSTFQ--DESSLYFLLEYAPNG-DFLSLMKK--YGSLDETCARYYAAQIIDAIDYLHSNG-IIHRDIKPENILL</Hsp_hseq>
      <Hsp_midline>+G G +STV L   +  K   A KV+       +    ++K +   +    K  N   VV+L   F+    + L+  + +   G   L  + K  Y  L   C +    Q++  +DYLH+   IIH DIKPENILL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3232984349</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054868-RA transcript Note:&quot;Similar to RELN Reelin (Homo sapiens)&quot; offset:0 AED:0.30 eAED:0.32 QI:0|0|0|0.75|0.97|0.95|45|0|2400</Iteration_query-def>
  <Iteration_query-len>7203</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>106</Statistics_hsp-len>
      <Statistics_eff-space>5082201765</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054873-RA transcript Note:&quot;Similar to Plxna1 Plexin-A1 (Mus musculus)&quot; offset:0 AED:0.17 eAED:0.17 QI:0|0|0|0.66|1|1|3|0|568</Iteration_query-def>
  <Iteration_query-len>1707</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1084069758</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0042112-RA transcript Note:&quot;Similar to PLXNA4 Plexin-A4 (Homo sapiens)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.5|0.55|9|32|380</Iteration_query-def>
  <Iteration_query-len>1175</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>92</Statistics_hsp-len>
      <Statistics_eff-space>689753233</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0034088-RA transcript Note:&quot;Similar to Plxna1 Plexin-A1 (Mus musculus)&quot; offset:0 AED:0.26 eAED:0.26 QI:0|0|0|0.70|0.37|0.35|17|0|768</Iteration_query-def>
  <Iteration_query-len>2307</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1528038624</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0035298-RA transcript Note:&quot;Similar to tes Testin (Xenopus laevis)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.11|0|10|1487|602</Iteration_query-def>
  <Iteration_query-len>3296</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2249558866</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054874-RA transcript Note:&quot;Similar to CACNA1D Voltage-dependent L-type calcium channel subunit alpha-1D (Mesocricetus auratus)&quot; offset:0 AED:0.27 eAED:0.27 QI:0|0|0|0.66|1|1|3|0|167</Iteration_query-def>
  <Iteration_query-len>504</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>83</Statistics_hsp-len>
      <Statistics_eff-space>201132695</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054875-RA transcript Note:&quot;Similar to Cacna1d Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)&quot; offset:0 AED:0.35 eAED:0.35 QI:0|0|0|0.85|1|1|28|0|1219</Iteration_query-def>
  <Iteration_query-len>3660</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2514915573</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054876-RA transcript Note:&quot;Similar to IL17RA Interleukin-17 receptor A (Homo sapiens)&quot; offset:532 AED:0.13 eAED:0.13 QI:532|0.25|0.6|0.8|0.75|0.6|5|977|485</Iteration_query-def>
  <Iteration_query-len>2967</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>2011993630</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054850-RA transcript Note:&quot;Similar to LRRC17 Leucine-rich repeat-containing protein 17 (Homo sapiens)&quot; offset:855 AED:0.01 eAED:0.01 QI:855|1|1|1|0.33|0.25|4|1844|469</Iteration_query-def>
  <Iteration_query-len>4109</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>102</Statistics_hsp-len>
      <Statistics_eff-space>2839178489</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054851-RA transcript Note:&quot;Similar to LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens)&quot; offset:0 AED:0.24 eAED:0.24 QI:0|1|1|1|0.2|0.18|11|435|177</Iteration_query-def>
  <Iteration_query-len>969</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>540575611</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054852-RA transcript Note:&quot;Similar to LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens)&quot; offset:0 AED:0.13 eAED:0.13 QI:0|0.5|0.52|0.95|0.6|0.57|21|0|682</Iteration_query-def>
  <Iteration_query-len>2049</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.7962</Hsp_bit-score>
      <Hsp_score>190</Hsp_score>
      <Hsp_evalue>1.67577e-15</Hsp_evalue>
      <Hsp_query-from>1519</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>201</Hsp_hit-from>
      <Hsp_hit-to>358</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>164</Hsp_align-len>
      <Hsp_qseq>SELAVLSRSRHPSLVSLLAV--GLRPRVLVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPD------------GTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>AERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLL-----NQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKA-YSQNCDWYSLGCLLYDMLVG</Hsp_hseq>
      <Hsp_midline>+E ++LS   HP++V L           L+++  P G L   ++  G L  T     A  ++  LRFLH   ++YRDLKP+N LL     N      + D+G+++       V  +            GTP Y APE++ G   Y Q  D Y+ G LLYD+L G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.1814</Hsp_bit-score>
      <Hsp_score>191</Hsp_score>
      <Hsp_evalue>2.10404e-15</Hsp_evalue>
      <Hsp_query-from>1501</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>603</Hsp_hit-from>
      <Hsp_hit-to>764</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>171</Hsp_align-len>
      <Hsp_qseq>RTPAIASELAVLSRSRHPSLVSLLAVGLRPRV---LVMELAPRGSLAGVMER---EGELHRTLKH----RIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIA-----RHCCTMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>RKELIVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDT-----RARVKITDFGFCARLTDKRSKRATMV---GTPYWMAPEVVKQR-EYDEKIDVWSLGIMTIEMLEG</Hsp_hseq>
      <Hsp_midline>R   I +E+ V+  SRH ++V+ L   LR      +VME    GSL  ++E        H  L       I      GL+FLH   II+RD+K DNVLL T         KI D+G       +      MV   GTP + APEVVK    YD++ DV++ G++  ++L G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.0258</Hsp_bit-score>
      <Hsp_score>188</Hsp_score>
      <Hsp_evalue>2.59843e-15</Hsp_evalue>
      <Hsp_query-from>1498</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>240</Hsp_hit-from>
      <Hsp_hit-to>417</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>180</Hsp_align-len>
      <Hsp_qseq>ARTPAIASELAVLSRSRHPSLVSLLAVGLRP-------RVLVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLL-FTLQPNAAVI-------------AKIADYGIARHCCTMGMVSP-DGTPGYRAPEVV-KGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>KKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKKG--YTSKVDLWSAGVILYVCLCG</Hsp_hseq>
      <Hsp_midline> +      E  +L R +HP++V+LL   + P       + LV+E    G L   + R+  L +     +   +  GL++LH   II+RD+KP+N+LL  T + N + +              KIAD+G+A+    M   +   GTP Y APEV+ K G  Y  + D+++ G++LY  L G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.9442</Hsp_bit-score>
      <Hsp_score>180</Hsp_score>
      <Hsp_evalue>3.71052e-14</Hsp_evalue>
      <Hsp_query-from>1480</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>410</Hsp_hit-from>
      <Hsp_hit-to>578</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>182</Hsp_align-len>
      <Hsp_qseq>LGELPPARTPAIASELAVLSRSRHPSLVSLLAVGL---RPRVLVMELAPRGSLAGVM---------EREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIA-----RHCCTMGMVSPDGTPGYRAPEVV--KGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>LSEQP--KKQLIMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILL-----NSQGLVKITDFGFCVELTEKRSKRATMV---GTPYWMAPEIVNQKG---YDEKVDVWSLGIMLIEMIEG</Hsp_hseq>
      <Hsp_midline>L E P  +   I +EL V++ SR  ++V+ L   +       ++ME    G L  ++         E    L+      I      GL+FLH   II+RD+K DN+LL     N+  + KI D+G       +      MV   GTP + APE+V  KG   YD++ DV++ G++L +++ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>7.49739e-14</Hsp_evalue>
      <Hsp_query-from>1450</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>114</Hsp_hit-from>
      <Hsp_hit-to>279</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>175</Hsp_align-len>
      <Hsp_qseq>FSLEQSAEHLLGELPPARTPAIASELAVLSRSRHPSLVSLLAVGLRPR--VLVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>YALKTLKKHTIVKL--KQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENIL---LDKNGHI--KITDFGFAKYVPDV-TYTLCGTPDYIAPEVVSTKP-YNKSVDWWSFGVLIYEMLAG</Hsp_hseq>
      <Hsp_midline>++L+   +H + +L   +      E  +LS   HP ++ +       +   +VM+    G L  ++ +       +    A  V   L +LH+  IIYRDLKP+N+L   L  N  +  KI D+G A++   +   +  GTP Y APEVV     Y++  D ++FG+L+Y++L G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>1.00699e-13</Hsp_evalue>
      <Hsp_query-from>1522</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>118</Hsp_hit-from>
      <Hsp_hit-to>261</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>151</Hsp_align-len>
      <Hsp_qseq>ELAVLSRSRHPSLVSLLAVGLRPR--VLVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>ERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENIL---LDRNGHI--KITDFGFAKEVQTVTW-TLCGTPDYIAPEVITTKP-YNKSVDWWSLGVLIYEMLAG</Hsp_hseq>
      <Hsp_midline>E  +L    HP L+ +       R   +VM+    G L  ++ +       +    A  V   L +LHA  IIYRDLKP+N+L   L  N  +  KI D+G A+   T+   +  GTP Y APEV+     Y++  D ++ G+L+Y++L G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>2.44083e-13</Hsp_evalue>
      <Hsp_query-from>1522</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>135</Hsp_hit-from>
      <Hsp_hit-to>278</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>151</Hsp_align-len>
      <Hsp_qseq>ELAVLSRSRHPSLVSLLAVGLRPR--VLVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>ERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENIL---LDKNGHI--KITDFGFAKYVPDV-TYTLCGTPDYIAPEVVSTKP-YNKSIDWWSFGILIYEMLAG</Hsp_hseq>
      <Hsp_midline>E  +LS   HP ++ +       +   ++M+    G L  ++ +       +    A  V   L +LH+  IIYRDLKP+N+L   L  N  +  KI D+G A++   +   +  GTP Y APEVV     Y++  D ++FG+L+Y++L G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.8626</Hsp_bit-score>
      <Hsp_score>172</Hsp_score>
      <Hsp_evalue>4.12325e-13</Hsp_evalue>
      <Hsp_query-from>1510</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>240</Hsp_hit-from>
      <Hsp_hit-to>404</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>168</Hsp_align-len>
      <Hsp_qseq>AIASELAVLSRSRHPSLVSLLAV--GLRPRVLVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIAR-HCCTMGMVSPDGTPGYRAPEVVKGGVM------------YDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>GVTRELEVLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDP---VLVKITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTG</Hsp_hseq>
      <Hsp_midline> +  EL VL +  HP +V L           +VME    G L   +   G +       I+  +   ++++H+  I +RDLKPDN+L+    P   V+ KI D+G+A+       M +  GT  Y APEV++G               Y    D+++ G L+Y +LTG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>5.52978e-13</Hsp_evalue>
      <Hsp_query-from>1510</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>82</Hsp_hit-from>
      <Hsp_hit-to>235</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>157</Hsp_align-len>
      <Hsp_qseq>AIASELAVLSRSRHPSLVSLLA--VGLRPRVLVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMG--MVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>ALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLV--VADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQD-GHGKPCDIWSIGVITYTLLCG</Hsp_hseq>
      <Hsp_midline>A+  EL +L R  HP++V+            ++ +LA  G L   + ++G+       RI + +   ++++H+  I++RDLKP+N+L       + ++  +AD+GIA+   +    +  P G+ GY APEV+     + +  D+++ G++ Y LL G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>1.16345e-12</Hsp_evalue>
      <Hsp_query-from>1510</Hsp_query-from>
      <Hsp_query-to>1962</Hsp_query-to>
      <Hsp_hit-from>255</Hsp_hit-from>
      <Hsp_hit-to>439</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>186</Hsp_align-len>
      <Hsp_qseq>AIASELAVLSRSRHPSLVSLLAVG---------------------LRPRVLVMELAPRGSL-AGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLL---------FTLQP--NAAVIAKIADYGIARHCCTMGMVSPD-GTPGYRAPEVVKGGVMYDQQ-ADVYAFGLLLYDLL</Hsp_qseq>
      <Hsp_hseq>SLTRELQVLKSLNHPCIVKLLGINNPIFVTSKKPLCDLIIKTPRALPPCDMIMSYCPAGDLLAAVMARNGRLEAWLIQRIFTEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLCKKIENNEMCTARCGSEDYVSPEILM-GVPYDGHLSDTWALGVILYSLF</Hsp_hseq>
      <Hsp_midline>++  EL VL    HP +V LL +                      L P  ++M   P G L A VM R G L   L  RI   V   +++LH + II+RDLK +N+LL         F   P        ++AD+G+ +      M +   G+  Y +PE++  GV YD   +D +A G++LY L </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>1.68473e-12</Hsp_evalue>
      <Hsp_query-from>1489</Hsp_query-from>
      <Hsp_query-to>2010</Hsp_query-to>
      <Hsp_hit-from>55</Hsp_hit-from>
      <Hsp_hit-to>226</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>190</Hsp_align-len>
      <Hsp_qseq>LPPARTPAIAS----ELAVLSRSRHPSLVSLLAVGLRPRVLVMELAPRGSLAGVMEREG-ELHRTLKHR---------IALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIAR--HCCTMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTGGRRIVEGLRYPHEF</Hsp_qseq>
      <Hsp_hseq>MKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFL---------SPLEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILI-----NENCDLKICDFGLARIQDPQMTGYVS---TRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIE-GKPLFPGKDHVHQF</Hsp_hseq>
      <Hsp_midline>+ P  T  +A     EL +L   RH +L+ L  + L         +P   +  V E +G +LHR L+ R             +  GL+++H++ +I+RDLKP N+L+     N     KI D+G+AR       G VS   T  YRAPE++     YD + D+++ G +  +++  G+ +  G  + H+F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>3.56324e-12</Hsp_evalue>
      <Hsp_query-from>1552</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>238</Hsp_hit-from>
      <Hsp_hit-to>385</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>154</Hsp_align-len>
      <Hsp_qseq>PSLVSLLAVGLRPRVL--VMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIAR--HCCTMGMVSPD-----------GTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>PSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILL-----DGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFT-DYRCDIWAFGCILFQMIAG</Hsp_hseq>
      <Hsp_midline>PS+V L +       L  ++E AP G    +M++ G L  T     A  +   + +LH++ II+RD+KP+N+LL     +  +  K+ D+G A+  +     +  P+           GT  Y +PE++      D + D++AFG +L+ ++ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>4.19453e-12</Hsp_evalue>
      <Hsp_query-from>1507</Hsp_query-from>
      <Hsp_query-to>1974</Hsp_query-to>
      <Hsp_hit-from>1078</Hsp_hit-from>
      <Hsp_hit-to>1250</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>178</Hsp_align-len>
      <Hsp_qseq>PAIASELAVLSRSRHPSLVSLLAVGL-RPRV-LVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCC------------------TMGMVSPDGTPGYRAPEVVKGGVMYDQQA--DVYAFGLLLYDLLTGGR</Hsp_qseq>
      <Hsp_hseq>PLIKEEMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEYCEGGSLASLLDHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILL-----DFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRR</Hsp_hseq>
      <Hsp_midline>P I  E+ VL    HP++V    V + R +V + ME    GSLA +++        +       +  GL +LH S +++RD+KP+N+LL     +   I K  D+G AR                     T  +    GTP Y APE + G  +  +    DV+A G ++ ++ TG R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>4.22685e-12</Hsp_evalue>
      <Hsp_query-from>1513</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>97</Hsp_hit-from>
      <Hsp_hit-to>248</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>157</Hsp_align-len>
      <Hsp_qseq>IASELAVLSRSRHPSLVSLLAVGLRPRVL--VMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMG--MVSPDGTPGYRAPEVVKGGVMYD-QQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>IYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLL---LDKNENLV--ITDFGFVNEFCSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAG</Hsp_hseq>
      <Hsp_midline>I  E+  L    HP++V L  V    R +  V+E A  G     ++++  L      R+   +  G+ ++H+  +++RDLK +N+L   L  N  ++  I D+G     C+    M +  G+P Y APE+V     Y+ ++AD+++ G++LY +L G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>6.39685e-12</Hsp_evalue>
      <Hsp_query-from>1513</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>74</Hsp_hit-from>
      <Hsp_hit-to>223</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>155</Hsp_align-len>
      <Hsp_qseq>IASELAVLSRSRHPSLVSLLAV--GLRPRVLVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPD-GTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>IEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLL-----DSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTG</Hsp_hseq>
      <Hsp_midline>I  E+ ++    HP+++SL  V        L++E A +G L  ++   G L           +  G+ + HA  I++RDLKP+N+LL     ++    KIAD+G+A       ++    G+P Y APE+V G       +DV++ G++L+ LLTG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>7.18341e-12</Hsp_evalue>
      <Hsp_query-from>1513</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>61</Hsp_hit-from>
      <Hsp_hit-to>213</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>158</Hsp_align-len>
      <Hsp_qseq>IASELAVLSRSRHPSLVSLLAVGLRPRVL--VMELAPRGSLAGVMERE--GELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHC-CTMGMVSPDGTPGYRAPEVVKGGV-MYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>LAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILL-----NEEGMVKLGDFGVSGHIRSTLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKG</Hsp_hseq>
      <Hsp_midline>+A E+  L+  + P + + +A  L    +  VME    GS + +++R     L       I   V  GL++LH    I+RD+K  N+LL     N   + K+ D+G++ H   T+   +  GTP + APEVV   V  Y+++AD+++ G+  Y+LL G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>9.2127e-12</Hsp_evalue>
      <Hsp_query-from>1465</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>61</Hsp_hit-from>
      <Hsp_hit-to>227</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>SAEHLLGELPPARTP-AIASELAVLSRSRHPSLVSLLAV--GLRPRVLVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPD-GTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>SGTSIVGSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLL-----DHKYNIKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTG</Hsp_hseq>
      <Hsp_midline>S   ++G   P   P  I  E+ ++    HP+++ L  V        LV+E A +G L  ++   G L      R    +  G+ + HA  I++RDLKP+N+LL     +     KIAD+G+A       ++    G+P Y APE+V G       +DV++ G++L+ LLTG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>1.00404e-11</Hsp_evalue>
      <Hsp_query-from>1513</Hsp_query-from>
      <Hsp_query-to>1962</Hsp_query-to>
      <Hsp_hit-from>100</Hsp_hit-from>
      <Hsp_hit-to>246</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>154</Hsp_align-len>
      <Hsp_qseq>IASELAVLSRSRHPSLVSLLAVGLRPR---VLVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPD-GTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLL</Hsp_qseq>
      <Hsp_hseq>IEREISYLRLLRHPHIIKLYDV-IKSKDEIIMVIEYAGNELFDYIVQRD-KMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLL-----DEHLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVML</Hsp_hseq>
      <Hsp_midline>I  E++ L   RHP ++ L  V ++ +   ++V+E A       +++R+ ++      R    +   + + H   I++RDLKP+N+LL     +  +  KIAD+G++        +    G+P Y APEV+ G +    + DV++ G++LY +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>1.98158e-11</Hsp_evalue>
      <Hsp_query-from>1510</Hsp_query-from>
      <Hsp_query-to>1974</Hsp_query-to>
      <Hsp_hit-from>1224</Hsp_hit-from>
      <Hsp_hit-to>1378</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>AIASELAVLSRSRHPSLVSLLAVGLRPRV--LVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTM---GMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTGGR</Hsp_qseq>
      <Hsp_hseq>ALRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLL-----DQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKR</Hsp_hseq>
      <Hsp_midline>A+ SE++ L    H ++V  L    +  +  L +E    GS+  ++   G     L   +   V  GL +LH+  I++RD+K DN+LL     +   I KI+D+GI+R    +     ++  GT  + APE+V     Y  + D+++ G ++ ++  G R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>2.19162e-11</Hsp_evalue>
      <Hsp_query-from>1456</Hsp_query-from>
      <Hsp_query-to>2046</Hsp_query-to>
      <Hsp_hit-from>54</Hsp_hit-from>
      <Hsp_hit-to>258</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>214</Hsp_align-len>
      <Hsp_qseq>LEQSAEHLLGELP----PARTPAIASELAVLSRSRHPSLVSL--LAVGLRPRV------LVMELAPRGSLAGVMER--EGELHRTLKH--RIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHC-CTMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTGGRRIVEGLRYPHEFDELASSGKLPGP</Hsp_qseq>
      <Hsp_hseq>LTQDKKNWLGPFAIKKVPAHTEYKSRELQILRIADHPNIVKLQYFFTHLSPQDNKVYQHLAMECLPE-TLQIEINRYVTNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLV---DPETGVL-KICDFGSAKKLEHNQPSISYICSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLI-GKAIFQGQEPLLQLREIA---KLLGP</Hsp_hseq>
      <Hsp_midline>L Q  ++ LG       PA T   + EL +L  + HP++V L      L P+       L ME  P  +L   + R    +L   LKH       +A G+ +LH   + +RD+KP NVL+    P   V+ KI D+G A+        +S   +  YRAPE++ G   Y  Q D++  G ++ ++L  G+ I +G     +  E+A   KL GP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>2.68431e-11</Hsp_evalue>
      <Hsp_query-from>1507</Hsp_query-from>
      <Hsp_query-to>1974</Hsp_query-to>
      <Hsp_hit-from>1310</Hsp_hit-from>
      <Hsp_hit-to>1498</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>43</Hsp_gaps>
      <Hsp_align-len>194</Hsp_align-len>
      <Hsp_qseq>PAIASELAVLSRSRHPSLVSLLAVGL-RPRV-LVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMG----------------------------------MVSPDGTPGYRAPEVVKGGVMYDQQA--DVYAFGLLLYDLLTGGR</Hsp_qseq>
      <Hsp_hseq>PLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAALLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILL-----DFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRR</Hsp_hseq>
      <Hsp_midline>P I  E++VL    HP++VS   V + R +V + ME    GSLA ++E        +     L +  GL +LH S I++RD+KP+N+LL     +   + K  D+G A+     G                                  ++   GTP Y APE + G     +    DV++ G ++ +++TG R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>2.84522e-11</Hsp_evalue>
      <Hsp_query-from>1624</Hsp_query-from>
      <Hsp_query-to>2028</Hsp_query-to>
      <Hsp_hit-from>303</Hsp_hit-from>
      <Hsp_hit-to>423</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>135</Hsp_align-len>
      <Hsp_qseq>SLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTGGRRIVEGLRYPHEFDELASS</Hsp_qseq>
      <Hsp_hseq>TYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILL-----NEKGEIKLCDFGVSGEAVNSLAMTFTGTSFYMAPERIQGQP-YSVTCDVWSLGLTLLE--------VAGGRFPFESDKITQN</Hsp_hseq>
      <Hsp_midline>+   +++R G +   +  +IA  V  GL +LH   +I+RD+KP N+LL     N     K+ D+G++        ++  GT  Y APE ++G   Y    DV++ GL L +        V G R+P E D++  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>3.59734e-11</Hsp_evalue>
      <Hsp_query-from>1522</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>96</Hsp_hit-from>
      <Hsp_hit-to>245</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>153</Hsp_align-len>
      <Hsp_qseq>ELAVLSRSRHPSLVSLLA--VGLRPRVLVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMG--MVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>ELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLV--IADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQD-GHGKPCDIWSIGVITYTLLCG</Hsp_hseq>
      <Hsp_midline>EL++L +  HP++VS            +V +LA  G L   +   G+        I + +   + ++H+  +++RDLKP+NVL      N+ ++  IAD+GIA+        +    G+ GY APEV+     + +  D+++ G++ Y LL G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>6.30298e-11</Hsp_evalue>
      <Hsp_query-from>1633</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>313</Hsp_hit-from>
      <Hsp_hit-to>418</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>112</Hsp_align-len>
      <Hsp_qseq>GVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>NLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILL-----NENGQVKLCDFGVSGEAVNSLATTFTGTSFYMAPERIQGQP-YSVTSDVWSLGLTILEVANG</Hsp_hseq>
      <Hsp_midline> ++ER G +   +  +IA  V  GL +LH   +I+RD+KP N+LL     N     K+ D+G++         +  GT  Y APE ++G   Y   +DV++ GL + ++  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>6.96764e-11</Hsp_evalue>
      <Hsp_query-from>1597</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>201</Hsp_hit-from>
      <Hsp_hit-to>333</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>139</Hsp_align-len>
      <Hsp_qseq>LVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPDGTP---------------GYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>FLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILL-----DKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYT-DSRCDIWAFGCILYQMLAG</Hsp_hseq>
      <Hsp_midline> ++E AP G   G++++ G L+ T     A  +   +  LH   II+RD+KP+N+LL     +  +  K+ D+G A+        + DG P                Y +PE++      D + D++AFG +LY +L G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>6.98586e-11</Hsp_evalue>
      <Hsp_query-from>1504</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>98</Hsp_hit-from>
      <Hsp_hit-to>272</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>180</Hsp_align-len>
      <Hsp_qseq>TPAIASELAVLSRSRHPSLVSLLAVGLRPR----VLVMELAPRGSLAGVMEREGELHR------TLKH--RIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPD-----------GTPGYRAPEVVKGGVMYDQQA--DVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>NPRVNQEIEVMKRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLISS---NGTV--KISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFG</Hsp_hseq>
      <Hsp_midline> P +  E+ V+ R  H ++V L  +   P      LV+E   RG +    E + E+        T +   ++ L V  GL +LH+  I +RD+KP N+L+ +   N  V  KI+D+G+A    T                  GTP + APE+      Y   +  D+++ G+ +Y LL G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>2.18914e-10</Hsp_evalue>
      <Hsp_query-from>1510</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>160</Hsp_hit-from>
      <Hsp_hit-to>311</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>AIASELAVLSRSRHPSLVSLLAV--GLRPRVLVMELAPRGSLAGVMEREGELHRTLKHRIALH----VAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPD-GTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>GIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKL----PEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLD--KKNRRI--KIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTG</Hsp_hseq>
      <Hsp_midline> I  E+ ++    H ++++L  V        LV+E    G L   +  +G+L      R A+H    +  G+ + H+  I +RDLKP+N+LL   + N  +  KIAD+G+A       ++    G+P Y +PE+V G   +   +DV++ G++L+ LLTG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>3.42606e-10</Hsp_evalue>
      <Hsp_query-from>1615</Hsp_query-from>
      <Hsp_query-to>2019</Hsp_query-to>
      <Hsp_hit-from>97</Hsp_hit-from>
      <Hsp_hit-to>245</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>155</Hsp_align-len>
      <Hsp_qseq>PRGSLAGVMEREG----ELHRTLKHRIALHVAH----------GLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCC------TMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTGGRRIVEGLRYPHEFDEL</Hsp_qseq>
      <Hsp_hseq>PDGSINGLYLYEELMECDMHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLV-----NADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFL-GGKPIFKGKDYVNQLNQI</Hsp_hseq>
      <Hsp_midline>P GS+ G+   E     ++H+ +K    L  AH          GL+++H++ +++RDLKP N+L+     NA    KI D+G+AR         +  +     T  YRAPE++     Y +  DV++ G +L + L GG+ I +G  Y ++ +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>4.58626e-10</Hsp_evalue>
      <Hsp_query-from>1597</Hsp_query-from>
      <Hsp_query-to>1995</Hsp_query-to>
      <Hsp_hit-from>97</Hsp_hit-from>
      <Hsp_hit-to>227</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>137</Hsp_align-len>
      <Hsp_qseq>LVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHC--CTMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTGGRRI--VEGLR</Hsp_qseq>
      <Hsp_hseq>IIMEHCAGGSLRSLL-RPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLI-TNEGNV----KLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYCDVEALR</Hsp_hseq>
      <Hsp_midline>++ME    GSL  ++ R G++       I   +   L+ +H   +I+RD+K  NVL+ T + N     K+ D+G+A      ++   +  GTP + APEV+  GV YD + D+++ G+  Y++ TG      VE LR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>5.43487e-10</Hsp_evalue>
      <Hsp_query-from>1519</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>394</Hsp_hit-from>
      <Hsp_hit-to>541</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>158</Hsp_align-len>
      <Hsp_qseq>SELAVLSRSRHPSLVSLLAVGLRPRVLVMELA--PRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPD------GTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>AERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILL-DYQGHIA----LCDFGL----CKLNMKDDDKTDTFCGTPEYLAPELLL-GLGYTKAVDWWTLGVLLYEMLTG</Hsp_hseq>
      <Hsp_midline>+E  VL+R   P +V L      P  L   LA    G L   +++EG    +        +   L  LH   ++YRDLKP+N+LL   Q + A    + D+G+    C + M   D      GTP Y APE++  G+ Y +  D +  G+LLY++LTG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>7.02981e-10</Hsp_evalue>
      <Hsp_query-from>1513</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>662</Hsp_hit-from>
      <Hsp_hit-to>810</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>IASELAVLSRSRHPSLVSLL-AVGLRPRV-LVMELAPRGSLAGVMER----EGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPD--GTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>IINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVTHCILTEGQIGAVCRETLS-----GLEFLHSKGVLHRDIKSDNILL-----SMEGDIKLTDFGFCAQINELNLKRTTMVGTPYWMAPEVV-SRKEYGPKVDIWSLGIMIIEMIEG</Hsp_hseq>
      <Hsp_midline>I +E+ V+  S+HP++V+ + +  L+  + ++ME    GSL  V+      EG++    +  ++     GL FLH+  +++RD+K DN+LL     +     K+ D+G       + +      GTP + APEVV     Y  + D+++ G+++ +++ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>8.88538e-10</Hsp_evalue>
      <Hsp_query-from>1483</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>104</Hsp_hit-from>
      <Hsp_hit-to>277</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>179</Hsp_align-len>
      <Hsp_qseq>GELPPARTPAIAS------------ELAVLSRSRHPSLVSLLAVGLRPR--VLVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMG--MVSPDGTPGYRAPEVVKGG-VMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>GEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFF-----DSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIG</Hsp_hseq>
      <Hsp_midline>GE+  A+T A AS            E+ +     HP++V  +          +++E+ P GSL  +++R   L           +   ++++H+  +I+RDLK  N+       ++    KI D+G+A           +  GTP Y APEV+ G    +  + D+++ G++LY LL G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>1.10733e-09</Hsp_evalue>
      <Hsp_query-from>1519</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>391</Hsp_hit-from>
      <Hsp_hit-to>538</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>158</Hsp_align-len>
      <Hsp_qseq>SELAVLSRSRHPSLVSLLAVGLRPRVLVMELA--PRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPD------GTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>AERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILL-DYQGHIA----LCDFGL----CKLNMKDNDKTDTFCGTPEYLAPEILLGQ-GYTKTVDWWTLGILLYEMMTG</Hsp_hseq>
      <Hsp_midline>+E  VL+R   P +V L      P  L + LA    G L   ++ EG             +   L  LH   +IYRDLKP+N+LL   Q + A    + D+G+    C + M   D      GTP Y APE++ G   Y +  D +  G+LLY+++TG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>1.12467e-09</Hsp_evalue>
      <Hsp_query-from>1537</Hsp_query-from>
      <Hsp_query-to>1962</Hsp_query-to>
      <Hsp_hit-from>880</Hsp_hit-from>
      <Hsp_hit-to>1018</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>146</Hsp_align-len>
      <Hsp_qseq>SRSRHPSLVSLL-AVGLRPRV-LVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPD--GTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLL</Hsp_qseq>
      <Hsp_hseq>TKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQRLSVRRAKF-YAAEVLLALKYFHDNGVIYRDLKLENIL---LTPEGHI--KIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQ-EYTKAVDWWAFGVLLYQML</Hsp_hseq>
      <Hsp_midline>++++HP L +L  +     R+   ME    G L   ++ +    R  K   A  V   L++ H + +IYRDLK +N+L   L P   +  KIADYG+ +     G  +    GTP + APE++K    Y +  D +AFG+LLY +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>1.16651e-09</Hsp_evalue>
      <Hsp_query-from>1522</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>73</Hsp_hit-from>
      <Hsp_hit-to>263</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>192</Hsp_align-len>
      <Hsp_qseq>ELAVLSRSRHPSLVSLLAVGLRPR--VLVMELAPRGSLAGVMEREGEL------------------------HRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFT----LQPNAAV------------IAKIADYGIARHCCTMGMVSP-DGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>EIAILKKIKHPHIVGLIDCERTSTDFYLIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEIL-NYQKYNAKADLWSVGTVVFEMCCG</Hsp_hseq>
      <Hsp_midline>E+A+L + +HP +V L+          L+ME    G L  +++R  EL                        HR         +A  L+FL +  +++RD+KP N+LL T       + +             I KIAD+G AR      +     G+P Y APE++     Y+ +AD+++ G +++++  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>1.82819e-09</Hsp_evalue>
      <Hsp_query-from>1597</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>265</Hsp_hit-from>
      <Hsp_hit-to>416</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>153</Hsp_align-len>
      <Hsp_qseq>LVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLL----FT--LQPN-----------------------AAVIAKIADYGIARHCCTMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>IIQELLTGGEIFGEIVRLTYFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKNTKTPCGTVGYTAPEVVKDE-HYSMKVDMWGIGCVLYTMLCG</Hsp_hseq>
      <Hsp_midline>++ EL   G + G + R       L   +   +A  ++ +H+  +++RD+KP+N+L     FT  ++P                           I K+AD+G+++   +    +P GT GY APEVVK    Y  + D++  G +LY +L G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.5362</Hsp_bit-score>
      <Hsp_score>140</Hsp_score>
      <Hsp_evalue>2.10972e-09</Hsp_evalue>
      <Hsp_query-from>1513</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>62</Hsp_hit-from>
      <Hsp_hit-to>218</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>162</Hsp_align-len>
      <Hsp_qseq>IASELAVLSR-SRHPSLVSLLAVGLRPRVL--VMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASM-IIYRDLKPDNVLLFTLQPNAAVIAKIADYGIA---RHCCTMGMVSPD--GTPGYRAPEVVKGGV-MYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>ITKEVVLQSKCSKHPNVLRLIDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENILL---DKNGNL--KLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTG</Hsp_hseq>
      <Hsp_midline>I  E+ + S+ S+HP+++ L+   +    +  ++E+A  G L   +E +  +   +       +   + +LH    + +RD+KP+N+LL     N  +  K+AD+G+A   R       VS D  G+P Y APEV+      Y  + D+++ G+LL+ LLTG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>2.24772e-09</Hsp_evalue>
      <Hsp_query-from>1522</Hsp_query-from>
      <Hsp_query-to>1971</Hsp_query-to>
      <Hsp_hit-from>152</Hsp_hit-from>
      <Hsp_hit-to>298</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>ELAVLSRSRHPSLV-SLLAVGLRPRV-LVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPD--------GTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTGG</Hsp_qseq>
      <Hsp_hseq>EVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILI-----GFNNVIKLTDFG-------WSIINPPENRRKTVCGTIDYLSPEMVESR-EYDHTIDAWALGVLAFELLTGA</Hsp_hseq>
      <Hsp_midline>E+ + +   HP+L  S        RV L+ME    G +  ++   G  +  L       +A+ L ++H   II+RD+KP+N+L+         + K+ D+G         +++P         GT  Y +PE+V+    YD   D +A G+L ++LLTG </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>2.64167e-09</Hsp_evalue>
      <Hsp_query-from>1417</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>211</Hsp_hit-from>
      <Hsp_hit-to>400</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>204</Hsp_align-len>
      <Hsp_qseq>VPDHLQLDLSSFSLEQSAEHLLGELPPARTPAIASELAVLSRSR-HPSLVSLLAVGLRPRV-----LVMELAPRGSLAGVME-------------REGELHRTLKHRIALHVAHGLRFLHASM-IIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>VPDSKIVAKKTIPVEQNNSTIINQL--------VRELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLI-----NSKGQIKLCDFGVSKKLINSIADTFVGTSTYMSPERIQGNV-YSIKGDVWSLGLMIIELVTG</Hsp_hseq>
      <Hsp_midline>VPD   +   +  +EQ+   ++ +L          EL+++   + H ++++         +     ++ME +  GSL  ++              ++   +     +IA  V +GL  L+    II+RD+KP NVL+     N+    K+ D+G+++        +  GT  Y +PE ++G V Y  + DV++ GL++ +L+TG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>2.82418e-09</Hsp_evalue>
      <Hsp_query-from>1519</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>210</Hsp_hit-from>
      <Hsp_hit-to>381</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>174</Hsp_align-len>
      <Hsp_qseq>SELAVLSRSRHPSLVSLLAVGLRPR---VLVMELAPRGSLAGVMEREG---ELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMG--MVSPDGTPGYRAPEV------------VKGGVM----YDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>KEARILLRLDHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIV--LADFGIAKDLNSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTG</Hsp_hseq>
      <Hsp_midline> E  +L R  HP+++ +            +  +L P G L   + +      +  T    I   +   L +LH   I++RDLK DN+LL T +P   ++  +AD+GIA+   +    M +  GTP Y APEV             +   +    YD + D+++ G++ + +LTG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>3.67798e-09</Hsp_evalue>
      <Hsp_query-from>1513</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>97</Hsp_hit-from>
      <Hsp_hit-to>248</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>157</Hsp_align-len>
      <Hsp_qseq>IASELAVLSRSRHPSLVSLLAVGLRPRVL--VMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMG--MVSPDGTPGYRAPEVVKGGVMYD-QQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>IYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLL---LDKHENLV--ITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAG</Hsp_hseq>
      <Hsp_midline>I  E+  L    HP+++ L  V    + +  V+E    G     ++R+  L  +   R+   +  G+ ++H   +++RDLK +N+L   L  +  ++  I D+G           M +  G+P Y APE+V     Y+ ++ADV++ G++LY +L G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>6.02939e-09</Hsp_evalue>
      <Hsp_query-from>1504</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>46</Hsp_hit-from>
      <Hsp_hit-to>205</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>166</Hsp_align-len>
      <Hsp_qseq>TPAIA-SELAVLSRSRHPSLVSLLAV--GLRPRVLVMELAPRGSLAGVMERE--GELHRTLKHRIALHVA----HGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCC--TMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>TPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMD-NDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLI-----NKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITG</Hsp_hseq>
      <Hsp_midline>TP+ A  E++++   +H ++V L  V        LV E      L   M+    G   R L+  +  +       GL F H + I++RDLKP N+L+     N     K+ D+G+AR          S   T  YRAP+V+ G   Y    D+++ G +L +++TG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YFL005W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:130334:130981:1 gene:YFL005W transcript:YFL005W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SEC4 description:Rab family GTPase; essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane [Source:SGD;Acc:S000001889]</Hit_def>
  <Hit_accession>YFL005W</Hit_accession>
  <Hit_len>215</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>6.43436e-09</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>375</Hsp_query-to>
      <Hsp_hit-from>21</Hsp_hit-from>
      <Hsp_hit-to>150</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>131</Hsp_align-len>
      <Hsp_qseq>MKLMVMGSAGRGKSTLLRRLQREKLLVS-TATLGVDVRDWAVLHRQRKFVLNCWDFAGQEEFYSTHPCFMSQRALYVLVYDASRGPNEVASLRPWLMNIKVRA-PLCPVILVGTHEDK----IAAEEKETL</Hsp_qseq>
      <Hsp_hseq>MKILLIGDSGVGKSCLLVRFVEDKFNPSFITTIGIDFKIKTVDINGKKVKLQLWDTAGQERFRTITTAYYRGAMGIILVYDVTD-ERTFTNIKQWFKTVNEHANDEAQLLLVGNKSDMETRVVTADQGEAL</Hsp_hseq>
      <Hsp_midline>MK++++G +G GKS LL R   +K   S   T+G+D +   V    +K  L  WD AGQE F +    +       +LVYD +       +++ W   +   A     ++LVG   D     + A++ E L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>7.30815e-09</Hsp_evalue>
      <Hsp_query-from>1498</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>77</Hsp_hit-from>
      <Hsp_hit-to>245</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>173</Hsp_align-len>
      <Hsp_qseq>ARTPAIAS-ELAVLSRSRHPSLVSLLAV-----------GLRPRVLVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLR---FLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCC-TMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>VKSPKVQSLELEILQNIRHPNLVTLEFFFESHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILII---PSSG-IAKVCDFGSAQRLDDNTELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKG</Hsp_hseq>
      <Hsp_midline> ++P + S EL +L   RHP+LV+L               L  +  VME  P+   + + E      +     I L+    LR    LH+  I + DLKP N+L+    P++  IAK+ D+G A+       + +   +  YRAPE++     Y  Q D+++ G ++ +++ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>1.67527e-08</Hsp_evalue>
      <Hsp_query-from>1510</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>500</Hsp_hit-from>
      <Hsp_hit-to>653</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>AIASELAVLSRSRHPSLVSLLAVGLRPRVL--VMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGM-----VSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>ALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILI-----DIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATT-AKADIWSTGCVVIEMFTG</Hsp_hseq>
      <Hsp_midline>A+  E+ +L    H ++V+          L   +E  P GS++ ++   G    +L       +  G+ +LH   II+RD+K  N+L+     +     KI D+GI++    +        S  G+  + +PEVVK       +AD+++ G ++ ++ TG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>2.62796e-08</Hsp_evalue>
      <Hsp_query-from>1525</Hsp_query-from>
      <Hsp_query-to>2010</Hsp_query-to>
      <Hsp_hit-from>73</Hsp_hit-from>
      <Hsp_hit-to>235</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>175</Hsp_align-len>
      <Hsp_qseq>LAVLSRSRHPSLVSLLAVGLRPRVLVMELAPRGSLAGVMEREGELHRTLK----HRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMG---------MVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTGGRRIVEGLRYPHEF</Hsp_qseq>
      <Hsp_hseq>ISILDKVRPVSIDKLNAV-----YLVEELM-ETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLL-----NSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVS-GKPLFPGRDYHHQL</Hsp_hseq>
      <Hsp_midline>+++L + R  S+  L AV      LV EL     L  V+  +     TL           +   L+ +H++ +I+RD+KP N+LL     N+    K+ D+G+AR   +           M     T  YRAPE++     Y    D+++ G +L ++++ G+ +  G  Y H+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>2.73831e-08</Hsp_evalue>
      <Hsp_query-from>1522</Hsp_query-from>
      <Hsp_query-to>2007</Hsp_query-to>
      <Hsp_hit-from>59</Hsp_hit-from>
      <Hsp_hit-to>231</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>181</Hsp_align-len>
      <Hsp_qseq>ELAVLSRSRHPSLVSLLAVGLRP-------RVLVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIAR------------HCCTMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTGGRRIVEGLRYPHE</Hsp_qseq>
      <Hsp_hseq>EIKILKHFKHENIITIFNIQ-RPDSFENFNEVYIIQELMQTDLHRVISTQMLSDDHIQYFI-YQTLRAVKVLHGSNVIHRDLKPSNLLI-----NSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFL-RRPIFPGRDYRHQ</Hsp_hseq>
      <Hsp_midline>E+ +L   +H +++++  +  RP        V +++   +  L  V+  +      +++ I       ++ LH S +I+RDLKP N+L+     N+    K+ D+G+AR                 GM     T  YRAPEV+     Y +  DV++ G +L +L    R I  G  Y H+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YML001W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:267174:267800:1 gene:YML001W transcript:YML001W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPT7 description:Rab family GTPase; GTP-binding protein of the rab family; required for homotypic fusion event in vacuole inheritance, for endosome-endosome fusion; localizes to sites of contact between the vacuole and mitochondria (vCLAMPs); interacts with the cargo selection/retromer complex for retrograde sorting; similar to mammalian Rab7 [Source:SGD;Acc:S000004460]</Hit_def>
  <Hit_accession>YML001W</Hit_accession>
  <Hit_len>208</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>4.88573e-08</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>408</Hsp_query-to>
      <Hsp_hit-from>9</Hsp_hit-from>
      <Hsp_hit-to>145</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>143</Hsp_align-len>
      <Hsp_qseq>MKLMVMGSAGRGKSTLLRRLQREKLLVS-TATLGVD-VRDWAVLHRQRKFVLNCWDFAGQEEFYSTHPCFMSQRALYVLVYDASRGPNEVASLRPW----LMNIKVRAP-LCPVILVGTHEDKIAAEEKETLMGSSVRCIEEL</Hsp_qseq>
      <Hsp_hseq>LKVIILGDSGVGKTSLMHRYVNDKYSQQYKATIGADFLTKEVTVDGDKVATMQVWDTAGQERFQSLGVAFYRGADCCVLVYDVTNASS-FENIKSWRDEFLVHANVNSPETFPFVILG---NKIDAEESKKIV--SEKSAQEL</Hsp_hseq>
      <Hsp_midline>+K++++G +G GK++L+ R   +K      AT+G D +     +   +   +  WD AGQE F S    F       VLVYD +   +   +++ W    L++  V +P   P +++G   +KI AEE + ++  S +  +EL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>4.91358e-08</Hsp_evalue>
      <Hsp_query-from>1522</Hsp_query-from>
      <Hsp_query-to>1962</Hsp_query-to>
      <Hsp_hit-from>54</Hsp_hit-from>
      <Hsp_hit-to>199</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>155</Hsp_align-len>
      <Hsp_qseq>ELAVLSRSRHPSLVSLLAVGL--RPRVLVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIAR------HCCTMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLL</Hsp_qseq>
      <Hsp_hseq>EVKYLQEMQHPNVIELIDIFMAYDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLF---SPDGQI--KVADFGLARAIPAPHEILTSNVV----TRWYRAPELLFGAKHYTSAIDIWSVGVIFAELM</Hsp_hseq>
      <Hsp_midline>E+  L   +HP+++ L+ + +      LV+E  P      + ++             L    G+   H + I++RDLKP+N+L     P+  +  K+AD+G+AR         T  +V    T  YRAPE++ G   Y    D+++ G++  +L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>5.54326e-08</Hsp_evalue>
      <Hsp_query-from>1678</Hsp_query-from>
      <Hsp_query-to>2016</Hsp_query-to>
      <Hsp_hit-from>814</Hsp_hit-from>
      <Hsp_hit-to>948</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>140</Hsp_align-len>
      <Hsp_qseq>RIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHC----------------CTMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLL----TGGRR--IVEGLR-----YPHEFDE</Hsp_qseq>
      <Hsp_hseq>RLFRQILEALSYIHSQGIIHRDLKPMNIFI-----DESRNVKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVLDGTGHYNEKIDMYSLGIIFFEMIYPFSTGMERVNILKKLRSVSIEFPPDFDD</Hsp_hseq>
      <Hsp_midline>R+   +   L ++H+  II+RDLKP N+ +     + +   KI D+G+A++                  +  + S  GT  Y A EV+ G   Y+++ D+Y+ G++ ++++    TG  R  I++ LR     +P +FD+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>5.91471e-08</Hsp_evalue>
      <Hsp_query-from>1597</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>490</Hsp_hit-from>
      <Hsp_hit-to>608</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>127</Hsp_align-len>
      <Hsp_qseq>LVMELAPRGSLAGVMEREGELHRTLKHRIALHVAH---GLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>LVTDYMSGGELFWHLQKEG---RFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILL-----DANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCG</Hsp_hseq>
      <Hsp_midline>LV +    G L   +++EG   R  + R   ++A     L  LH + I+YRDLKP+N+LL     +A     + D+G+++        +  GT  Y APE++     Y +  D ++ G+L++++  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>6.26712e-08</Hsp_evalue>
      <Hsp_query-from>1597</Hsp_query-from>
      <Hsp_query-to>1959</Hsp_query-to>
      <Hsp_hit-from>525</Hsp_hit-from>
      <Hsp_hit-to>646</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>128</Hsp_align-len>
      <Hsp_qseq>LVMELAPRGSLAG-----VMEREGELHRTLKHRIALHVAHGLRFLHASM-IIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHC-CTMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDL</Hsp_qseq>
      <Hsp_hseq>IMTELCENGNLDGFLQEQVIAKKKRLEDWRIWKIIVELSLALRFIHDSCHIVHLDLKPANVMI-TFEGNL----KLGDFGMATHLPLEDKSFENEGDREYIAPEII-SDCTYDYKADIFSLGLMIVEI</Hsp_hseq>
      <Hsp_midline>++ EL   G+L G     V+ ++  L      +I + ++  LRF+H S  I++ DLKP NV++ T + N     K+ D+G+A H          +G   Y APE++     YD +AD+++ GL++ ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>1.11656e-07</Hsp_evalue>
      <Hsp_query-from>1690</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>140</Hsp_hit-from>
      <Hsp_hit-to>228</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>94</Hsp_align-len>
      <Hsp_qseq>HVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSP-DGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>QISGAVYYAHSMHCVHRDLKLENILL-----DKNGNAKLTDFGFTRECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITG</Hsp_hseq>
      <Hsp_midline> ++  + + H+   ++RDLK +N+LL     +    AK+ D+G  R C T   +    GT  Y APE+++       + D+++ G++LY L+TG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YLR262C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:668244:668891:-1 gene:YLR262C transcript:YLR262C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPT6 description:Rab family GTPase; required for endosome-to-Golgii, intra-Golgi retrograde, and retrograde Golgi-to-ER transport; temporarily at the Golgi, dissociating into the cytosol on arrival of the late Golgi GTPase Ypt32p; Golgi-localized form is GTP bound, while cytosolic form is GDP-bound; required for delivery of Atg9p to the phagophore assembly site during autophagy under heat stress, with Ypt6p for starvation induced autophagy and for the CVT pathway; homolog of mammalian Rab6 [Source:SGD;Acc:S000004252]</Hit_def>
  <Hit_accession>YLR262C</Hit_accession>
  <Hit_len>215</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>1.55586e-07</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>390</Hsp_query-to>
      <Hsp_hit-from>12</Hsp_hit-from>
      <Hsp_hit-to>150</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>140</Hsp_align-len>
      <Hsp_qseq>KLMVMGSAGRGKSTLLRRLQREKLLVS-TATLGVDVRDWAVLHRQRKFVLNCWDFAGQEEFYSTHPCFMSQRALYVLVYDASRGPNEVASLRPWLMNIKVRAPLCPVIL--VGTHED-----KIAAEE---KETLMGSSV</Hsp_qseq>
      <Hsp_hseq>KIVFLGEQGVGKTSLITRFMYDTFDDHYQATIGIDFLSKTMYLDDKTIRLQLWDTAGQERFRSLIPSYIRDSRVAIIVYDITKRKS-FEYIDKWIEDVKNERGDENVILCIVGNKSDLSDERQISTEEGEKKAKLLGAKI</Hsp_hseq>
      <Hsp_midline>K++ +G  G GK++L+ R   +       AT+G+D     +    +   L  WD AGQE F S  P ++    + ++VYD ++  +    +  W+ ++K       VIL  VG   D     +I+ EE   K  L+G+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>2.24836e-07</Hsp_evalue>
      <Hsp_query-from>1486</Hsp_query-from>
      <Hsp_query-to>2004</Hsp_query-to>
      <Hsp_hit-from>394</Hsp_hit-from>
      <Hsp_hit-to>564</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>183</Hsp_align-len>
      <Hsp_qseq>ELPPARTPAIASELAVLSRSRHPSLVSLL-AVGLRPRV-LVMELAPRGSLAGVMEREGELHRTLKHRIAL---HVAHGLRFLHAS-MIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPDGTPGYRAPEVVKG----GVMYDQQADVYAFGLLLYDLLTGGRRIVEGLRYPH</Hsp_qseq>
      <Hsp_hseq>ELDEAKFRQILMELEVLHKCNSPYIVDFYGAFFIEGAVYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSANQG----TVKLCDFGVSGNLVASLAKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALG--------RYPY</Hsp_hseq>
      <Hsp_midline>EL  A+   I  EL VL +   P +V    A  +   V + ME    GSL  + +   E+    + ++A     V HGL+ L     II+RD+KP N+L    Q       K+ D+G++ +       +  G   Y APE +K        Y  Q+D+++ GL + ++  G        RYP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>2.72167e-07</Hsp_evalue>
      <Hsp_query-from>1636</Hsp_query-from>
      <Hsp_query-to>1947</Hsp_query-to>
      <Hsp_hit-from>145</Hsp_hit-from>
      <Hsp_hit-to>274</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>132</Hsp_align-len>
      <Hsp_qseq>VME-REGELHRTLKHR------------IALHVAHGLRFLHASMIIYRDLKPDNVLL--------------FTLQPNAAVIAKIADYGIARHCCTMG-MVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLL</Hsp_qseq>
      <Hsp_hseq>VMECMEQNLYQMMKHRRRRVFSIPSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVI--KLADFGLARHVENKNPYTAYVSTRWYRSPEILLRSGYYSKPLDIWAFGCV</Hsp_hseq>
      <Hsp_midline>VME  E  L++ +KHR            I   +  GL+ +H     +RDLKP+N+L+                 Q N  +  K+AD+G+ARH        +   T  YR+PE++     Y +  D++AFG +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YGL210W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:93792:94460:1 gene:YGL210W transcript:YGL210W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPT32 description:Rab family GTPase involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi; protein abundance increases in response to DNA replication stress; YPT32 has a paralog, YPT31, that arose from the whole genome duplication [Source:SGD;Acc:S000003178]</Hit_def>
  <Hit_accession>YGL210W</Hit_accession>
  <Hit_len>222</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>3.31239e-07</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>345</Hsp_query-to>
      <Hsp_hit-from>14</Hsp_hit-from>
      <Hsp_hit-to>129</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>117</Hsp_align-len>
      <Hsp_qseq>MKLMVMGSAGRGKSTLLRRLQREKLLV-STATLGVDVRDWAVLHRQRKFVLNCWDFAGQEEFYSTHPCFMSQRALYVLVYDASRGPNEVASLRPWLMNIKVRA-PLCPVILVGTHED</Hsp_qseq>
      <Hsp_hseq>FKIVLIGDSGVGKSNLLSRFTTDEFNIESKSTIGVEFATRTIEVENKKIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDISK-SSSYENCNHWLTELRENADDNVAVGLIGNKSD</Hsp_hseq>
      <Hsp_midline> K++++G +G GKS LL R   ++  + S +T+GV+     +    +K     WD AGQE + +    +       ++VYD S+  +   +   WL  ++  A     V L+G   D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YJR059W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:545787:548243:1 gene:YJR059W transcript:YJR059W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK2 description:Serine/threonine protein kinase; involved in regulation of ion transport across plasma membrane; carboxyl terminus is essential for glucose-dependent Pma1p activation via phosphorylation of Pma1p-Ser899; enhances spermine uptake; PTK2 has a paralog, PTK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003820]</Hit_def>
  <Hit_accession>YJR059W</Hit_accession>
  <Hit_len>818</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>3.87833e-07</Hsp_evalue>
      <Hsp_query-from>1597</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>339</Hsp_hit-from>
      <Hsp_hit-to>478</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>146</Hsp_align-len>
      <Hsp_qseq>LVMELAPRGSLAGVMEREGELHRTLKHRIAL--HVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIAR--HCCTMGMVSP-------DGTPGYRAPEVV----------KGGVMYDQQA-DVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>FIMELGVK-DLFQLMERTGWKNVPFNEKYCLFKQVAQGIKFCHDNGIAHRDLKPENVLI-----SKEGICKLTDFGISDWYHVIPHDYTSPVKTCQGMIGSPPYTPPEVMYFDAKKHYPEKFQKPYNPLAMDSYALGIMLITMINN</Hsp_hseq>
      <Hsp_midline> +MEL  +  L  +MER G  +     +  L   VA G++F H + I +RDLKP+NVL+     +   I K+ D+GI+   H       SP        G+P Y  PEV+          K    Y+  A D YA G++L  ++  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>4.68952e-07</Hsp_evalue>
      <Hsp_query-from>1465</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>44</Hsp_hit-from>
      <Hsp_hit-to>226</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>191</Hsp_align-len>
      <Hsp_qseq>SAEHLLGELPPARTPAIASELAVLSRSRHPSLVSLLAVGLRPRVL--VMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLL--------------FTLQP----NAAVIAKIADYGIARHCCTMGMVSPDGTPGYRAPEVVKGGVMYDQ---QADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>SKKHIIKEAKVKYVTIEKNTMNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFV----GTAEYVSPEL----LLYNQCGYGSDIWALGCMIYQFVQG</Hsp_hseq>
      <Hsp_midline>S +H++ E          + + +L++  H  ++ L         L  V++ AP G L  ++ + G  +          +   L F+H+  II+RDLKP+NVLL               T+ P    ++A     ++       C   +    GT  Y +PE+    ++Y+Q    +D++A G ++Y  + G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>5.96739e-07</Hsp_evalue>
      <Hsp_query-from>1678</Hsp_query-from>
      <Hsp_query-to>1965</Hsp_query-to>
      <Hsp_hit-from>115</Hsp_hit-from>
      <Hsp_hit-to>207</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>102</Hsp_align-len>
      <Hsp_qseq>RIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIAR------HCCTMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLT</Hsp_qseq>
      <Hsp_hseq>KFMMQLCKGIAYCHSHRILHRDLKPQNLLI-----NKDGNLKLGDFGLARAFGVPLRAYTHEIV----TLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCN</Hsp_hseq>
      <Hsp_midline>+  + +  G+ + H+  I++RDLKP N+L+     N     K+ D+G+AR         T  +V    T  YRAPEV+ GG  Y    D ++ G +  ++  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>6.02675e-07</Hsp_evalue>
      <Hsp_query-from>1690</Hsp_query-from>
      <Hsp_query-to>1962</Hsp_query-to>
      <Hsp_hit-from>1213</Hsp_hit-from>
      <Hsp_hit-to>1298</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>91</Hsp_align-len>
      <Hsp_qseq>HVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLL</Hsp_qseq>
      <Hsp_hseq>QVVAGIKHLHDQGIVHRDIKDENVIV-----DSKGFVKIIDFGSAAYVKSGPFDVFVGTIDYAAPEVLGGNPYEGQPQDIWAIGILLYTVV</Hsp_hseq>
      <Hsp_midline> V  G++ LH   I++RD+K +NV++     ++    KI D+G A +  +       GT  Y APEV+ G     Q  D++A G+LLY ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>7.41711e-07</Hsp_evalue>
      <Hsp_query-from>1522</Hsp_query-from>
      <Hsp_query-to>2043</Hsp_query-to>
      <Hsp_hit-from>230</Hsp_hit-from>
      <Hsp_hit-to>398</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>179</Hsp_align-len>
      <Hsp_qseq>ELAVLSRSRHPSLVSLLAVGLRPR---VLVMELAPRGSLAGVMEREGEL-HRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMG-MVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTGGRRIVEGLRYPHEFDELASSGKLPG</Hsp_qseq>
      <Hsp_hseq>EIKLLQSFDHPNVSTIKEIMVESQKTVYMIFEYADNDLSGLLLNKEVQISHSQCKH-LFKQLLLGMEYLHDNKILHRDVKGSNILI----DNQGNL-KITDFGLARKMNSRADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKT-AIFQG---SNELEQIESIFKIMG</Hsp_hseq>
      <Hsp_midline>E+ +L    HP++ ++  + +  +    ++ E A       ++ +E ++ H   KH +   +  G+ +LH + I++RD+K  N+L+     N   + KI D+G+AR   +     +   T  YR PE++ G   Y  + D++  G LL +L      I +G    +E +++ S  K+ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>7.80942e-07</Hsp_evalue>
      <Hsp_query-from>1597</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>200</Hsp_hit-from>
      <Hsp_hit-to>319</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>125</Hsp_align-len>
      <Hsp_qseq>LVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIAR-HCCTMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>MLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMI-----SSSGEIKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCG</Hsp_hseq>
      <Hsp_midline>++ E    G L   + + G L      + A  +A  L++LHA+ I++RDLK +N+++     +++   KI D+G++        + +  G+  + APE++K       + D+++FG++LY L+ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YFL029C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:78055:79161:-1 gene:YFL029C transcript:YFL029C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CAK1 description:Cyclin-dependent kinase-activating kinase; required for passage through the cell cycle; phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases [Source:SGD;Acc:S000001865]</Hit_def>
  <Hit_accession>YFL029C</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>8.62053e-07</Hsp_evalue>
      <Hsp_query-from>1690</Hsp_query-from>
      <Hsp_query-to>1950</Hsp_query-to>
      <Hsp_hit-from>139</Hsp_hit-from>
      <Hsp_hit-to>234</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>96</Hsp_align-len>
      <Hsp_qseq>HVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPD---------GTPGYRAPEVVKGGVMYDQQADVYAFGLLL</Hsp_qseq>
      <Hsp_hseq>QMVEGIAFLHENKIIHRDIKPQNIMLTNNTSTVSPKLYIIDFGISYDMANNSQTSAEPMDSKVTDISTGIYKAPEVLFGVKCYDGGVDVWSLLIII</Hsp_hseq>
      <Hsp_midline> +  G+ FLH + II+RD+KP N++L       +    I D+GI+         S +          T  Y+APEV+ G   YD   DV++  +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YBR264C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:737770:738369:-1 gene:YBR264C transcript:YBR264C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPT10 description:Rab family GTP-binding protein; contains the PEST signal sequence specific for proteolytic enzymes; may be involved in vesicular transport; overexpression leads to accumulation of Golgi-like cisternae with budding vesicles [Source:SGD;Acc:S000000468]</Hit_def>
  <Hit_accession>YBR264C</Hit_accession>
  <Hit_len>199</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>9.12696e-07</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>360</Hsp_query-to>
      <Hsp_hit-from>5</Hsp_hit-from>
      <Hsp_hit-to>130</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>133</Hsp_align-len>
      <Hsp_qseq>MKLMVMGSAGRGKSTLLRRLQREKLLVS----------TATLGVDVRDWAVLHRQRKFVLNCWDFAGQEEFYSTHPCFMSQRALYVLVYDASRGPNEVASL---RPWLMNIKVRAPLCPVILVGTHEDKIAAE</Hsp_qseq>
      <Hsp_hseq>IKVVLLGDSSVGKTSIVTRLKSGKFLAKHAATIGAAFITKTIEVPSNDSST---EKRIHMEIWDTAGQERYKSLVPMYYRDANIALIVFELG----DVSSLQCAKTWFQDLQDRAQGTQVIIVGNKYDLVCEE</Hsp_hseq>
      <Hsp_midline>+K++++G +  GK++++ RL+  K L            T T+ V   D +    +++  +  WD AGQE + S  P +     + ++V++      +V+SL   + W  +++ RA    VI+VG   D +  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YNL020C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:595623:597539:-1 gene:YNL020C transcript:YNL020C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ARK1 description:Serine/threonine protein kinase; involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis; ARK1 has a paralog, PRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004965]</Hit_def>
  <Hit_accession>YNL020C</Hit_accession>
  <Hit_len>638</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>1.08942e-06</Hsp_evalue>
      <Hsp_query-from>1564</Hsp_query-from>
      <Hsp_query-to>1959</Hsp_query-to>
      <Hsp_hit-from>96</Hsp_hit-from>
      <Hsp_hit-to>239</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>149</Hsp_align-len>
      <Hsp_qseq>SLLAVGLRPRVLVMELAPRGSLAGVMER--EGELHRTLKHRIALHVAHGLRFLHASM--IIYRDLKPDNVLLFTLQPNAAVIAKIADYGIA-------RHCCTMGMVSPD----GTPGYRAPEVVKG--GVMYDQQADVYAFGLLLYDL</Hsp_qseq>
      <Hsp_hseq>AMLHNGSYEVFVLMEYCERGGLIDFMNTRLQNRLHEFEILQIMSQVTQGVAAMHALQPPLIHRDIKIENVLI-----SANNEYKLCDFGSVCGIIRPPRNSQELSYVQQDILKNTTAQYRSPEMIDTFRGLPIDEKSDIWALGIFLYKL</Hsp_hseq>
      <Hsp_midline>++L  G     ++ME   RG L   M    +  LH     +I   V  G+  +HA    +I+RD+K +NVL+     +A    K+ D+G         R+   +  V  D     T  YR+PE++    G+  D+++D++A G+ LY L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>1.79842e-06</Hsp_evalue>
      <Hsp_query-from>1681</Hsp_query-from>
      <Hsp_query-to>1962</Hsp_query-to>
      <Hsp_hit-from>175</Hsp_hit-from>
      <Hsp_hit-to>277</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>108</Hsp_align-len>
      <Hsp_qseq>IALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIAR--HCCTMGMVSPDG------------TPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLL</Hsp_qseq>
      <Hsp_hseq>MMLQILEGLNYIHCAKFMHRDIKTANILI-----DHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFF</Hsp_hseq>
      <Hsp_midline>+ L +  GL ++H +  ++RD+K  N+L+     +   + K+AD+G+AR  + C   +  P G            T  YRAPE+V G   Y    D++  G +  +  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YOR089C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:490196:490828:-1 gene:YOR089C transcript:YOR089C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VPS21 description:Endosomal Rab family GTPase; required for endocytic transport and sorting of vacuolar hydrolases; required for endosomal localization of the CORVET complex; required with YPT52 for MVB biogenesis and sorting; involved in autophagy and ionic stress tolerance; geranylgeranylation required for membrane association; protein abundance increases in response to DNA replication stress; mammalian Rab5 homolog; VPS21 has a paralog, YPT53, that arose from the whole genome duplication [Source:SGD;Acc:S000005615]</Hit_def>
  <Hit_accession>YOR089C</Hit_accession>
  <Hit_len>210</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.3654</Hsp_bit-score>
      <Hsp_score>111</Hsp_score>
      <Hsp_evalue>1.95428e-06</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>375</Hsp_query-to>
      <Hsp_hit-from>8</Hsp_hit-from>
      <Hsp_hit-to>141</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>135</Hsp_align-len>
      <Hsp_qseq>MKLMVMGSAGRGKSTLLRRLQREKLLVSTA-TLGVDVRDWAVLHRQRKFVLNCWDFAGQEEFYSTHPCFMSQRALYVLVYDASRGPNEVASLRPWLMNIKVRAPLCPVI-LVGTH--------EDKIAAEEKETL</Hsp_qseq>
      <Hsp_hseq>IKLVLLGEAAVGKSSIVLRFVSNDFAENKEPTIGAAFLTQRVTINEHTVKFEIWDTAGQERFASLAPMYYRNAQAALVVYDVTK-PQSFIKARHWVKELHEQASKDIIIALVGNKIDMLQEGGERKVAREEGEKL</Hsp_hseq>
      <Hsp_midline>+KL+++G A  GKS+++ R        +   T+G       V   +       WD AGQE F S  P +       ++VYD ++ P      R W+  +  +A    +I LVG          E K+A EE E L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>2.05007e-06</Hsp_evalue>
      <Hsp_query-from>1597</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>221</Hsp_hit-from>
      <Hsp_hit-to>340</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>125</Hsp_align-len>
      <Hsp_qseq>LVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIAR-HCCTMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>MLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMI----SDSSEI-KIIDFGLSNIYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCG</Hsp_hseq>
      <Hsp_midline>++ E    G L   + + G +      + A  +A  L +LHA+ I++RDLK +N+++     +++ I KI D+G++  +     + +  G+  + APE++K       + DV++FG++L+ L+ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>2.17519e-06</Hsp_evalue>
      <Hsp_query-from>1627</Hsp_query-from>
      <Hsp_query-to>1950</Hsp_query-to>
      <Hsp_hit-from>128</Hsp_hit-from>
      <Hsp_hit-to>240</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>118</Hsp_align-len>
      <Hsp_qseq>LAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIAR-------HCCTM---GMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLL</Hsp_qseq>
      <Hsp_hseq>LAKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILC-TL--NGCL--KICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCIL</Hsp_hseq>
      <Hsp_midline>LA V+    +L           +  GL+++H++ +I+RDLKP N+L  TL  N  +  KI D+G+AR        C +     + +   T  YRAPE++     Y +  D++A G +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>71</Hit_num>
  <Hit_id>YBR164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:567875:568426:-1 gene:YBR164C transcript:YBR164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ARL1 description:Soluble GTPase with a role in regulation of membrane traffic; regulates potassium influx; role in membrane organization at trans-Golgi network; required for delivery of Atg9p to the phagophore assembly site during autophagy under high temperature stress; required with Ypt6p for starvation-induced autophagy; required for the CVT pathway under non-starvation conditions; G protein of the Ras superfamily, similar to ADP-ribosylation factor [Source:SGD;Acc:S000000368]</Hit_def>
  <Hit_accession>YBR164C</Hit_accession>
  <Hit_len>183</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.2098</Hsp_bit-score>
      <Hsp_score>108</Hsp_score>
      <Hsp_evalue>3.22057e-06</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>246</Hsp_query-to>
      <Hsp_hit-from>19</Hsp_hit-from>
      <Hsp_hit-to>96</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>22</Hsp_identity>
      <Hsp_positive>43</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>82</Hsp_align-len>
      <Hsp_qseq>MKLMVMGSAGRGKSTLLRRLQREKLLVSTATLGVDVRDWAVLHRQRKFVLNCWDFAGQEEFYSTHPCFMSQRALYVLVYDAS</Hsp_qseq>
      <Hsp_hseq>LRILILGLDGAGKTTILYRLQIGEVVTTKPTIGFNVETLSY----KNLKLNVWDLGGQTSIRPYWRCYYADTAAVIFVVDST</Hsp_hseq>
      <Hsp_midline>++++++G  G GK+T+L RLQ  +++ +  T+G +V   +     +   LN WD  GQ        C+ +  A  + V D++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>72</Hit_num>
  <Hit_id>YKL168C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:131288:133462:-1 gene:YKL168C transcript:YKL168C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KKQ8 description:Putative serine/threonine protein kinase with unknown cellular role; KKQ8 has a paralog, HAL5, that arose from the whole genome duplication [Source:SGD;Acc:S000001651]</Hit_def>
  <Hit_accession>YKL168C</Hit_accession>
  <Hit_len>724</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>3.82712e-06</Hsp_evalue>
      <Hsp_query-from>1594</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>510</Hsp_hit-from>
      <Hsp_hit-to>640</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>139</Hsp_align-len>
      <Hsp_qseq>VLVMELAPRGSLAGVM----EREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIA---------RHCCTMGMVSPDGTPGYRAPEVVKGGVMYDQQ-ADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>IEVMEFCPAGDLYGMLVGKSKLKGRLHPLEADCFMKQLLHGVKFMHDHGIAHCDLKPENILFY---PHG--LLKICDFGTSSVFQTAWERRVHAQKGII---GSEPYVAPEEFVDGEYYDPRLIDCWSCGVVYITMILG</Hsp_hseq>
      <Hsp_midline>+ VME  P G L G++    + +G LH          + HG++F+H   I + DLKP+N+L +   P+   + KI D+G +         R     G++   G+  Y APE    G  YD +  D ++ G++   ++ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>73</Hit_num>
  <Hit_id>YER031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:214076:214747:-1 gene:YER031C transcript:YER031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPT31 description:Rab family GTPase; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi; YPT31 has a paralog, YPT32, that arose from the whole genome duplication; localizes to the transitional and late Golgi [Source:SGD;Acc:S000000833]</Hit_def>
  <Hit_accession>YER031C</Hit_accession>
  <Hit_len>223</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.595</Hsp_bit-score>
      <Hsp_score>109</Hsp_score>
      <Hsp_evalue>4.0647e-06</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>345</Hsp_query-to>
      <Hsp_hit-from>14</Hsp_hit-from>
      <Hsp_hit-to>129</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>117</Hsp_align-len>
      <Hsp_qseq>MKLMVMGSAGRGKSTLLRRLQREKL-LVSTATLGVDVRDWAVLHRQRKFVLNCWDFAGQEEFYSTHPCFMSQRALYVLVYDASRGPNEVASLRPWLMNIKVRA-PLCPVILVGTHED</Hsp_qseq>
      <Hsp_hseq>FKIVLIGDSGVGKSNLLSRFTKNEFNMDSKSTIGVEFATRTLEIDGKRIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDISKSS-SYENCNHWLSELRENADDNVAVGLIGNKSD</Hsp_hseq>
      <Hsp_midline> K++++G +G GKS LL R  + +  + S +T+GV+     +    ++     WD AGQE + +    +       ++VYD S+      +   WL  ++  A     V L+G   D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>74</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>4.75995e-06</Hsp_evalue>
      <Hsp_query-from>1513</Hsp_query-from>
      <Hsp_query-to>1971</Hsp_query-to>
      <Hsp_hit-from>67</Hsp_hit-from>
      <Hsp_hit-to>215</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>156</Hsp_align-len>
      <Hsp_qseq>IASELAVLSRSRHPSLVSLLAVGLRPRVL--VMELAPRGSLAGVMEREGE-LHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTGG</Hsp_qseq>
      <Hsp_hseq>IMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILL-----SADNTVKLADFGVST-IVNSSALTLAGTLNWMAPEIL-GNRGASTLSDIWSLGATVVEMLTKN</Hsp_hseq>
      <Hsp_midline>I +E+++L    H ++V       +   L  ++E    GSL  ++ R    L              GL++LH   +I+RD+K  N+LL     +A    K+AD+G++        ++  GT  + APE++ G       +D+++ G  + ++LT  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>75</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>6.19006e-06</Hsp_evalue>
      <Hsp_query-from>1513</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>189</Hsp_hit-from>
      <Hsp_hit-to>375</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>192</Hsp_align-len>
      <Hsp_qseq>IASELAVLSRSRHPSLVSLLAV--GLRPR--VLVMELAPRGSLA----GVMEREGELHRTLKHR----IALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPD------------GTPGYRAPEVVKG----------------GVMYDQQADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>IKREIAIMKKCHHKHVVQLIEVLDDLKSRKIYLVLEYCSRGEVKWCPPDCMESDAKGPSLLSFQETREILRGVVLGLEYLHYQGIIHRDIKPANLLI-----SGDGTVKISDFGVSLAASSTNSSDSSESLDELELAKTVGTPAFFAPEMCLGEDAFTRYNLTKENLFRGSCISFMIDIWAVGVTLYCLLFG</Hsp_hseq>
      <Hsp_midline>I  E+A++ +  H  +V L+ V   L+ R   LV+E   RG +       ME + +    L  +    I   V  GL +LH   II+RD+KP N+L+     +     KI+D+G++    +                   GTP + APE+  G                G       D++A G+ LY LL G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>76</Hit_num>
  <Hit_id>YKL198C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:68232:70220:-1 gene:YKL198C transcript:YKL198C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK1 description:Putative serine/threonine protein kinase; regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein; PTK1 has a paralog, PTK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001681]</Hit_def>
  <Hit_accession>YKL198C</Hit_accession>
  <Hit_len>662</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.3654</Hsp_bit-score>
      <Hsp_score>111</Hsp_score>
      <Hsp_evalue>6.20474e-06</Hsp_evalue>
      <Hsp_query-from>1597</Hsp_query-from>
      <Hsp_query-to>1968</Hsp_query-to>
      <Hsp_hit-from>280</Hsp_hit-from>
      <Hsp_hit-to>419</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>151</Hsp_align-len>
      <Hsp_qseq>LVMELAPRGSLAGVMEREGELHRTLKHRIAL--HVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIA--------------RHCCTMGMVSPDGTPGYRAPEVV--KGGVMYDQQ---------ADVYAFGLLLYDLLTG</Hsp_qseq>
      <Hsp_hseq>FVMELGLR-DLFAMIQKSGWRSVALAEKFCIFKQVACGVKFCHDQGIAHRDLKPENVL---LSPDG--VCKLTDFGISDWYHTDPHDLSSPVKKCA--GMI---GSPPYAPPEVMFYDSKKHYDTELQQPYDPRALDCYGLGIILMTLVNN</Hsp_hseq>
      <Hsp_midline> VMEL  R  L  ++++ G     L  +  +   VA G++F H   I +RDLKP+NVL   L P+   + K+ D+GI+              + C   GM+   G+P Y  PEV+       YD +          D Y  G++L  L+  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>77</Hit_num>
  <Hit_id>YOR267C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:822588:824867:-1 gene:YOR267C transcript:YOR267C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRK1 description:Protein kinase; implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005793]</Hit_def>
  <Hit_accession>YOR267C</Hit_accession>
  <Hit_len>759</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.9802</Hsp_bit-score>
      <Hsp_score>110</Hsp_score>
      <Hsp_evalue>8.11195e-06</Hsp_evalue>
      <Hsp_query-from>1516</Hsp_query-from>
      <Hsp_query-to>1947</Hsp_query-to>
      <Hsp_hit-from>263</Hsp_hit-from>
      <Hsp_hit-to>410</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>158</Hsp_align-len>
      <Hsp_qseq>ASELAVLSRSRHPSLVSLLAV----GLRPRVLVMELAPRGSLAGVME---REGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIA---RHCCTMGMVSPDGTPG---YRAPEVVKGGVMYDQQA-DVYAFGLL</Hsp_qseq>
      <Hsp_hseq>TAEFCIGSTLHHPNVIETVDVFSDSKQNKYYEVMEYCPIDFFAVVMTGKMSRGEINCCLKQ-----LTEGVKYLHSMGLAHRDLKLDNCVM-----TSQGILKLIDFGSAVVFRYPFEDGVTMAHGIVGSDPYLAPEVITSTKSYDPQCVDIWSIGII</Hsp_hseq>
      <Hsp_midline> +E  + S   HP+++  + V           VME  P    A VM      GE++  LK      +  G+++LH+  + +RDLK DN ++      +  I K+ D+G A   R+    G+    G  G   Y APEV+     YD Q  D+++ G++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1338634129</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054853-RA transcript Note:&quot;Similar to Lrrk2 Leucine-rich repeat serine/threonine-protein kinase 2 (Mus musculus)&quot; offset:0 AED:0.86 eAED:0.86 QI:0|0|0|0.14|1|1|14|0|754</Iteration_query-def>
  <Iteration_query-len>2265</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1496204486</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054855-RA transcript Note:&quot;Similar to TMEM209 Transmembrane protein 209 (Homo sapiens)&quot; offset:411 AED:0.22 eAED:0.22 QI:411|0.54|0.66|1|0.90|0.83|12|236|409</Iteration_query-def>
  <Iteration_query-len>1877</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1206367043</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054857-RA transcript Note:&quot;Similar to QARS Glutamine--tRNA ligase (Bos taurus)&quot; offset:128 AED:0.24 eAED:0.26 QI:128|0.69|0.83|0.91|0.95|0.91|24|0|755</Iteration_query-def>
  <Iteration_query-len>2396</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YOR168W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:649303:651732:1 gene:YOR168W transcript:YOR168W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GLN4 description:Glutamine tRNA synthetase; monomeric class I tRNA synthetase that catalyzes the specific glutaminylation of tRNA(Gln); N-terminal domain proposed to be involved in enzyme-tRNA interactions [Source:SGD;Acc:S000005694]</Hit_def>
  <Hit_accession>YOR168W</Hit_accession>
  <Hit_len>809</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>429.098</Hsp_bit-score>
      <Hsp_score>1102</Hsp_score>
      <Hsp_evalue>5.34619e-139</Hsp_evalue>
      <Hsp_query-from>246</Hsp_query-from>
      <Hsp_query-to>2342</Hsp_query-to>
      <Hsp_hit-from>8</Hsp_hit-from>
      <Hsp_hit-to>794</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>283</Hsp_identity>
      <Hsp_positive>404</Hsp_positive>
      <Hsp_gaps>116</Hsp_gaps>
      <Hsp_align-len>801</Hsp_align-len>
      <Hsp_qseq>ARLLQVAGLSEAKALETLKNAPLAAALGLAVRQAQEASADGAVDRAMGTLLYGAAS--RGRDLRRFPTLATYIGAFCPSEYNAGQNVERAAAALEYLKSHPLEPLAVEEFERACGVGIVVTPEQIEETVEGVIKKYKSQLLEERYHFNMGLIMAETRGL--LKWADGKILKNEVDVQVLNMLGPKTESDRXXXXXXXXXXXXXXXXXGSVSAPTVNG--ENYKTEGYVVTPHTT--------RILQEHLARTGGQVRTRFPPEPNGILHIGHAKAINFNFGFAKANGGICFLRYDDTNPEKEEEKYFRGIRDMVEWLGYIPYAVTHASDHFQQLYVWAVELIKRGHAYICHQKSEELK-----------GYSVVASPWRDRPVAESLRLFEDMRKGKFAEGEVTLRMKLVMEDGK---MDPVAYRIKYTPHHRTGDTWCIYPTYDYTHCLCDSIEDITHSLCTKEFQTRRSSYFWLCNALDLYCPVQWEYGRLNLHYTVVSKRKIVRLIEEKICRAGIPA---AAQAVRLHQEPVGRRGPSRWVVGVTGAQTVIEPHLLEACVRDVLNETAPRAMAVLEPLRVVITN-------------------FPQSAVPAVG-----------------YRRLAPSQPVGLRHAGLIISLQDVVKDAGGRVVELRVT----CAPADAAVKPKAFVHWV------AQPLP-CEVRLYERLFLHKNPEDPAEVPGGFLKDINPESIRVLEGAMVD--------------SSVQGAAPF----------SKFQFERVGYFSVDPDSTAHK</Hsp_qseq>
      <Hsp_hseq>TQLFSQVGFEDKKVKEIVKNKKVSDSLYKLIK---ETPSDYQWNKSTRALVHNLASFVKGTDL---PKSELIVNGIINGDLKTSLQVD---AAFKYVKANG-EASTKMGMNENSGVGIEITEDQVRNYVMQYIQENKERILTERYKLVPG-IFADVKNLKELKWADPRSFKPIIDQEVLKLLGPKDERDLIKKKTKNNEKKKTNSAKKSSDNSASSGPKRTMFNEGFLGDLHKVGENPQAYPELMKEHLEVTGGKVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVSWLGFKPWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKEDGTPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAYRVLNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQVHVFRPAQREYGRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINTLGVTTSTTNIQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDNLSDDYEELATIPYRPGTPEFGERTVPFTNKFYIERSDFSENVDDKEFFRLTPNQPVGLIKVSHTVSFKSLEKDEAGKIIRIHVNYDNKVEEGSKPKKPKTYIQWVPISSKYNSPLRVTETRVYNQLF---KSENPSSHPEGFLKDINPESEVVYKESVMEHNFGDVVKNSPWVVDSVKNSEFYVEEDKDSKEVCRFQAMRVGYFTLDKESTTSK</Hsp_hseq>
      <Hsp_midline> +L    G  + K  E +KN  ++ +L   ++   E  +D   +++   L++  AS  +G DL   P     +      +      V+   AA +Y+K++  E           GVGI +T +Q+   V   I++ K ++L ERY    G I A+ + L  LKWAD +  K  +D +VL +LGPK E D  KK+     K +  +   S      +G       EG++   H           +++EHL  TGG+VRTRFPPEPNG LHIGH+KAI  NFG+AK + G C+LR+DDTNPEKE  +YF  I+ MV WLG+ P+ +T++SD+F +LY  A  LIK G AY+CH  +EE+K           G    A   RD+ + ++L+ F DMR GK+  GE  LRMK  +        D +AYR+   PH RTG  W IYPTYD+THCL DS+E+ITHSLCT EF   R SY WLC+ + ++ P Q EYGRLN+  TV+SKRKI +L++EK  R          +A+R    P G        +GVT + T I+    E+ VR  L +T PR M VL+P+ VV+ N                   F +  VP                    + RL P+QPVGL      +S + + KD  G+++ + V             KPK ++ WV        PL   E R+Y +LF     E+P+  P GFLKDINPES  V + ++++               SV+ +  +           +FQ  RVGYF++D +ST  K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YGL245W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:39023:41149:1 gene:YGL245W transcript:YGL245W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GUS1 description:Glutamyl-tRNA synthetase (GluRS); forms a complex with methionyl-tRNA synthetase (Mes1p) and Arc1p; complex formation increases the catalytic efficiency of both tRNA synthetases and ensures their correct localization to the cytoplasm; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003214]</Hit_def>
  <Hit_accession>YGL245W</Hit_accession>
  <Hit_len>708</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>217.624</Hsp_bit-score>
      <Hsp_score>553</Hsp_score>
      <Hsp_evalue>4.1493e-61</Hsp_evalue>
      <Hsp_query-from>963</Hsp_query-from>
      <Hsp_query-to>2321</Hsp_query-to>
      <Hsp_hit-from>200</Hsp_hit-from>
      <Hsp_hit-to>681</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>157</Hsp_identity>
      <Hsp_positive>254</Hsp_positive>
      <Hsp_gaps>59</Hsp_gaps>
      <Hsp_align-len>497</Hsp_align-len>
      <Hsp_qseq>GQVRTRFPPEPNGILHIGHAKAINFNFGFAKANGGICFLRYDDTNPEKEEEKYFRGIRDMVEWLGYIPYAVTHASDHFQQLYVWAVELIKRGHAYICHQKSEELKGYSV--VASPWRDRPVAESLRLF-EDMRKGKFAEGEVTLRMKL---VMEDGKMDPVAYRIKYTPHHRTGDTWCIYPTYDYTHCLCDSIEDITHSLCTKEFQTRRSSYFWLCNALDLYCPVQWEYGRLNLHYTVVSKRKIVRLIEEKICRA----------GIPAAAQAVRLHQEPVGRRGPSRWVVGVTGAQTVIEPHLLEACVRDVLNETAPRAMAVLEPLRVVI--TNFPQ----------SAVPAVGYRRLAPSQP--VGLRHAGLIISLQDVVKDAGGRVVELRVTCAPADAAV-----------KPKAFVHWVAQP---LPCEVRLYERLFLHKNPEDPAEVPGGFLKDINPESIRVLEGAMVDSSVQGAAPFSKFQFERVGYFSVD</Hsp_qseq>
      <Hsp_hseq>GEVVTRFPPEPSGYLHIGHAKAALLNQYFAQAYKGKLIIRFDDTNPSKEKEEFQDSILEDLDLLGIKGDRITYSSDYFQEMYDYCVQMIKDGKAYCDDTPTEKMREERMDGVASARRDRSVEENLRIFTEEMKNGTEEGLKNCVRAKIDYKALNKTLRDPVIYRCNLTPHHRTGSTWKIYPTYDFCVPIVDAIEGVTHALRTIEYRDRNAQYDWMLQALRLRKVHIWDFARINFVRTLLSKRKLQWMVDKDLVGNWDDPRFPTVRGVRRRGMTVEGLRNFVLSQGPSRNVIN-------LEWNLIWAFNKKVIDPIAPRHTAIVNPVKIHLEGSEAPQEPKIEMKPKHKKNPAVGEKKVIYYKDIVVDKDDADVINVDEEVTLMDWGNVI---ITKKNDDGSMVAKLNLEGDFKKTKHKLTWLADTKDVVPVDLVDFDHLI----TKDRLEEDESFEDFLTPQT-EFHTDAIADLNVKDMKIGDIIQFERKGYYRLD</Hsp_hseq>
      <Hsp_midline>G+V TRFPPEP+G LHIGHAKA   N  FA+A  G   +R+DDTNP KE+E++   I + ++ LG     +T++SD+FQ++Y + V++IK G AY     +E+++   +  VAS  RDR V E+LR+F E+M+ G     +  +R K+    +     DPV YR   TPHHRTG TW IYPTYD+   + D+IE +TH+L T E++ R + Y W+  AL L     W++ R+N   T++SKRK+  ++++ +             G+      V   +  V  +GPSR V+        +E +L+ A  + V++  APR  A++ P+++ +  +  PQ             PAVG +++   +   V    A +I   ++V     G V+   +T    D ++           K K  + W+A     +P ++  ++ L      +D  E    F   + P++      A+ D +V+        QFER GY+ +D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YOL033W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:263475:265085:1 gene:YOL033W transcript:YOL033W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MSE1 description:Mitochondrial glutamyl-tRNA synthetase; predicted to be palmitoylated [Source:SGD;Acc:S000005393]</Hit_def>
  <Hit_accession>YOL033W</Hit_accession>
  <Hit_len>536</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>3.20135e-08</Hsp_evalue>
      <Hsp_query-from>969</Hsp_query-from>
      <Hsp_query-to>1616</Hsp_query-to>
      <Hsp_hit-from>45</Hsp_hit-from>
      <Hsp_hit-to>276</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>233</Hsp_align-len>
      <Hsp_qseq>VRTRFPPEPNGILHIGHAKAINFNFGFAKANGGICFLRYDDTNPEKEEEKYFRGIRDMVEWLGYIPYAVTHASDHFQQLYV--WAVELIKRGHAYICHQKSEELKGYSVVASPWRDRPVAESLR----LFEDMRKGKFAEG-EVTLRMKLVMEDGKM-DPVAYRIKYTPH-----HRTGDTWCI----YPTYDYTHCLCDSIEDITHSLCTKEFQTRRSSYFWLCNALDLYCP</Hsp_qseq>
      <Hsp_hseq>VRTRFAPSPTGFLHLGSLRTALYNYLLARNTNGQFLLRLEDTDQKRLIEGAEENIYEILKWCN-INYDETPIKQSERKLIYDKYVKILLSSGKAYRCFCSKERLNDLRHSAMELKPPSMASYDRCCAHLGEEEIKSKLAQGIPFTVRFKSPERYPTFTDLLHGQINLQPQVNFNDKRYDDLILVKSDKLPTYHLANVVDDHLMGITHVIRGEEWLPSTPKHIALYNAFGWACP</Hsp_hseq>
      <Hsp_midline>VRTRF P P G LH+G  +   +N+  A+   G   LR +DT+ ++  E     I ++++W   I Y  T      ++L    +   L+  G AY C    E L      A   +   +A   R    L E+  K K A+G   T+R K         D +  +I   P       R  D   +     PTY   + + D +  ITH +  +E+      +  L NA    CP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1587086900</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054858-RA transcript Note:&quot;Similar to PIM1 Serine/threonine-protein kinase pim-1 (Homo sapiens)&quot; offset:218 AED:0.06 eAED:0.06 QI:218|1|1|1|0.8|0.83|6|1662|326</Iteration_query-def>
  <Iteration_query-len>2861</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>152.91</Hsp_bit-score>
      <Hsp_score>385</Hsp_score>
      <Hsp_evalue>3.4736e-38</Hsp_evalue>
      <Hsp_query-from>336</Hsp_query-from>
      <Hsp_query-to>1106</Hsp_query-to>
      <Hsp_hit-from>841</Hsp_hit-from>
      <Hsp_hit-to>1099</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>91</Hsp_identity>
      <Hsp_positive>143</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>265</Hsp_align-len>
      <Hsp_qseq>YRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDR--VTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERP----EAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEEILRAHVAFRK--RVSPECQELIRACLNVRPSERPLLDEILAHPWL</Hsp_qseq>
      <Hsp_hseq>FTILQVMGEGAYGKVNLCIHNREHYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATL---NKNSQENILKLLDFFEDDDYYYI--ETPVHGETGSIDLFDVIEFKKDMVEHEAKLVFKQVVASIKHLHDQGIVHRDIKDENVIVD-SHGFVKLIDFGSAAYIKSGPFDVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLYTIIYKENPYYNIDEILEGELRFDKSEHVSEECISLIKRILTREVDKRPTIDEIYEDKWL</Hsp_hseq>
      <Hsp_midline>+ +  V+G G +G V   +   ++  V IK + K+R  V  W +      +P E+ +M  +     +    +++LLD+FE  D + +  E P      + DLFD I  +  + E  A+  F+QVV +++H H  G++HRD+KDEN++VD   G +KLIDFGS A +K   +  F GT  Y+ PE +    Y G+   +W+LGVLLY ++  + P+ + +EIL   + F K   VS EC  LI+  L     +RP +DEI    WL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>152.91</Hsp_bit-score>
      <Hsp_score>385</Hsp_score>
      <Hsp_evalue>4.38805e-38</Hsp_evalue>
      <Hsp_query-from>354</Hsp_query-from>
      <Hsp_query-to>1106</Hsp_query-to>
      <Hsp_hit-from>1102</Hsp_hit-from>
      <Hsp_hit-to>1354</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>91</Hsp_identity>
      <Hsp_positive>142</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>259</Hsp_align-len>
      <Hsp_qseq>LGSGGFGTVYEGVRLSDNLPVAIKHVGKDR--VTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERP----EAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEEILRAHVAFR--KRVSPECQELIRACLNVRPSERPLLDEILAHPWL</Hsp_qseq>
      <Hsp_hseq>MGEGAYGKVNLCIHKKNRYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATL---NKKPHENILRLLDFFEDDDYYYI--ETPVHGETGCIDLFDLIEFKTNMTEFEAKLIFKQVVAGIKHLHDQGIVHRDIKDENVIVDSK-GFVKIIDFGSAAYVKSGPFDVFVGTIDYAAPEVLGGNPYEGQPQDIWAIGILLYTVVFKENPFYNIDEILEGDLKFNNAEEVSEDCIELIKSILNRCVPKRPTIDDINNDKWL</Hsp_hseq>
      <Hsp_midline>+G G +G V   +   +   V IK + K+R  V  W +      +P E+ +M  +      P   ++RLLD+FE  D + +  E P        DLFD I  +  + E  A+  F+QVV  ++H H  G++HRD+KDEN++VD K G +K+IDFGS A +K   +  F GT  Y+ PE +  + Y G+   +W++G+LLY +V  + PF + +EIL   + F   + VS +C ELI++ LN    +RP +D+I    WL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>120.553</Hsp_bit-score>
      <Hsp_score>301</Hsp_score>
      <Hsp_evalue>2.61038e-29</Hsp_evalue>
      <Hsp_query-from>336</Hsp_query-from>
      <Hsp_query-to>1154</Hsp_query-to>
      <Hsp_hit-from>47</Hsp_hit-from>
      <Hsp_hit-to>325</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>91</Hsp_identity>
      <Hsp_positive>136</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>291</Hsp_align-len>
      <Hsp_qseq>YRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMK-KVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENIL-VDLKRGE-LKLIDFGSGALLK---DTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPF--EHDEEILRA----------HVAFRKRVSPECQELIRACLNVRPSERPLLDEILAHPWLAESESEGEPALPLAKR</Hsp_qseq>
      <Hsp_hseq>YIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKKAL-------QGNNVQLQMLYEELSILQKLSHP--NIVSFKDWFESKDKFYIVTQLATGG-ELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYK-AAGSLGYVAPE-VLTQDGHGKPCDIWSIGVITYTLLCGYSPFIAESVEGFMEECTASRYPVTFHMPYWDNISIDVKRFILKALRLNPADRPTATELLDDPWITSKRVETSNILPDVKK</Hsp_hseq>
      <Hsp_midline>Y  G  LG+G FG V +  +LS N  VAIK + K  +        G  V L+++  +  +LQ  + P   ++   DWFE  D F ++ +      +LFD I  RG   E  A     Q++ AV + H+  V+HRDLK EN+L VD      L + DFG    LK   D +Y    G+  Y  PE +     HG+   +WS+GV+ Y ++CG  PF  E  E  +            H+ +   +S + +  I   L + P++RP   E+L  PW+     E    LP  K+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>123.635</Hsp_bit-score>
      <Hsp_score>309</Hsp_score>
      <Hsp_evalue>3.76224e-29</Hsp_evalue>
      <Hsp_query-from>336</Hsp_query-from>
      <Hsp_query-to>1112</Hsp_query-to>
      <Hsp_hit-from>19</Hsp_hit-from>
      <Hsp_hit-to>291</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>88</Hsp_identity>
      <Hsp_positive>137</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>282</Hsp_align-len>
      <Hsp_qseq>YRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALV------------PLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTDFD-GTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEEILRA----------HVAFRKRVSPECQELIRACLNVRPSERPLLDEILAHPWLAE</Hsp_qseq>
      <Hsp_hseq>WKLGETLGLGSTGKVQLARNGSTGQEAAVKVISK-AVFNTGNVSGTSIVGSTTPDALPYGIEREIIIMKLLNHPN------VLRLYDVWETNTDLYLVLEYAEKG-ELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYN-IKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERRIKTRDILKHPLLQK</Hsp_hseq>
      <Hsp_midline>+++G  LG G  G V      S     A+K + K  V   G +   ++V              E+++MK +          V+RL D +E      L++E  E   +LF+ + ERG L E  A  FFRQ++  V +CHA G++HRDLK EN+L+D K   +K+ DFG  AL  +    +   G+  Y+ PE +    Y G ++ VWS GV+L+ ++ G +PF+ ++  +R            +     +S E Q+LIR  L V P  R    +IL HP L +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>119.783</Hsp_bit-score>
      <Hsp_score>299</Hsp_score>
      <Hsp_evalue>2.42585e-28</Hsp_evalue>
      <Hsp_query-from>336</Hsp_query-from>
      <Hsp_query-to>1106</Hsp_query-to>
      <Hsp_hit-from>55</Hsp_hit-from>
      <Hsp_hit-to>306</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>128</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>264</Hsp_align-len>
      <Hsp_qseq>YRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTDFD-GTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHD------EEILRAHVAFRKRVSPECQELIRACLNVRPSERPLLDEILAHPWL</Hsp_qseq>
      <Hsp_hseq>YQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDM---QGRIEREISYLRLLRHPH------IIKLYDVIKSKDEIIMVIEY--AGNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLD-EHLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGAAGLIKRMLIVNPLNRISIHEIMQDDWF</Hsp_hseq>
      <Hsp_midline>Y++   LG G FG V      +    VA+K + K  + +         +  E+  ++ +          +I+L D  +  D  ++++E   A  +LFD+I +R  ++E  AR FF+Q++ AV +CH   ++HRDLK EN+L+D +   +K+ DFG   ++ D  +     G+  Y+ PE I    Y G    VWS GV+LY M+C  +PF+ +      + I        K +SP    LI+  L V P  R  + EI+   W </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>120.939</Hsp_bit-score>
      <Hsp_score>302</Hsp_score>
      <Hsp_evalue>3.20365e-28</Hsp_evalue>
      <Hsp_query-from>489</Hsp_query-from>
      <Hsp_query-to>1112</Hsp_query-to>
      <Hsp_hit-from>164</Hsp_hit-from>
      <Hsp_hit-to>371</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>215</Hsp_align-len>
      <Hsp_qseq>EVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGAL-LKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDE------EILRAHVAFRKRVSPECQELIRACLNVRPSERPLLDEILAHPWLAE</Hsp_qseq>
      <Hsp_hseq>EIVIMKLISHTN------VMALFEVWENKSELYLVLEYVDGG-ELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMPSNLSSEARDLISKILVIDPEKRITTQEILKHPLIKK</Hsp_hseq>
      <Hsp_midline>E+V+MK +          V+ L + +E      L++E  +   +LFD++  +G L E  A  +F+Q+VE V +CH+  + HRDLK EN+L+D K   +K+ DFG  AL L + +     G+  Y+ PE +    YHG  + VWS G++L+ ++ G +PF  D       ++          +S E ++LI   L + P +R    EIL HP + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>116.316</Hsp_bit-score>
      <Hsp_score>290</Hsp_score>
      <Hsp_evalue>8.42602e-27</Hsp_evalue>
      <Hsp_query-from>543</Hsp_query-from>
      <Hsp_query-to>1106</Hsp_query-to>
      <Hsp_hit-from>185</Hsp_hit-from>
      <Hsp_hit-to>377</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>196</Hsp_align-len>
      <Hsp_qseq>VIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHD------EEILRAHVAFRKRVSPECQELIRACLNVRPSERPLLDEILAHPWL</Hsp_qseq>
      <Hsp_hseq>ICRLFEMCTMSNHFYMLFEYVSGGQ-LLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMIS-SSGEIKIIDFGLSNIFDYRKQLHT-FCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYPSHLSIEVISLLTRMIVVDPLRRATLKNVVEHPWM</Hsp_hseq>
      <Hsp_midline>+ RL +    ++ F ++ E     + L D+I + G+L E  AR F R +  A+++ HA  ++HRDLK ENI++    GE+K+IDFG   +   +  ++T F G+  ++ PE ++   Y G    +WS G++LY +VCG +PF+ +      E+I +  V +   +S E   L+   + V P  R  L  ++ HPW+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>111.309</Hsp_bit-score>
      <Hsp_score>277</Hsp_score>
      <Hsp_evalue>2.70456e-26</Hsp_evalue>
      <Hsp_query-from>327</Hsp_query-from>
      <Hsp_query-to>1142</Hsp_query-to>
      <Hsp_hit-from>34</Hsp_hit-from>
      <Hsp_hit-to>311</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>85</Hsp_identity>
      <Hsp_positive>135</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>289</Hsp_align-len>
      <Hsp_qseq>EKLYRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMK-KVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLI--DFGSGALLK--DTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHD------------EEILRAHVAFRKRVSPECQELIRACLNVRPSERPLLDEILAHPWLAESESEGEPALP</Hsp_qseq>
      <Hsp_hseq>KKKYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKAL-------KGNKVQLEALYDELDILQRLHHP--NIVAFKDWFESKDKFYIITQLAKGG-ELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPE-VLTQDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAELLEDPWIICTELKTHNLLP</Hsp_hseq>
      <Hsp_midline>+K Y  G  LG+G FG V +         VA+K + K  +        G  V LE +  +  +LQ    P   ++   DWFE  D F +I +  +   +LFD I ++G   E  A     +++ AV++ H+  ++HRDLK EN+L   K  E  L+  DFG    LK  + +     G+  Y  PE +     HG+   +WS+GV+ Y ++CG   F  +            E  ++ H  +   VS + ++ I   LN+ PS+RP   E+L  PW+  +E +    LP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>113.62</Hsp_bit-score>
      <Hsp_score>283</Hsp_score>
      <Hsp_evalue>4.77092e-26</Hsp_evalue>
      <Hsp_query-from>336</Hsp_query-from>
      <Hsp_query-to>1121</Hsp_query-to>
      <Hsp_hit-from>21</Hsp_hit-from>
      <Hsp_hit-to>290</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>81</Hsp_identity>
      <Hsp_positive>137</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>278</Hsp_align-len>
      <Hsp_qseq>YRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSG-ALVPL----EVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTDFD-GTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEEILRA----------HVAFRKRVSPECQELIRACLNVRPSERPLLDEILAHPWLAESES</Hsp_qseq>
      <Hsp_hseq>WKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPN------VLSLYDVWETNNNLYLILEYAEKG-ELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLD-SFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQT</Hsp_hseq>
      <Hsp_midline>+++G  LG G  G V            A+K + K      G   +  +++P     E+V+MK +          V+ L D +E  ++  LI+E  E   +LF+ + + G L E  A   FRQ++  + +CHA G++HRDLK EN+L+D     +K+ DFG  AL  D    +   G+  Y+ PE +    Y G ++ VWS GV+L+ ++ G +PF+ +   +R            +     +S + Q+LI   L V P +R  + +IL+HP L + ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>110.153</Hsp_bit-score>
      <Hsp_score>274</Hsp_score>
      <Hsp_evalue>3.93592e-25</Hsp_evalue>
      <Hsp_query-from>342</Hsp_query-from>
      <Hsp_query-to>1115</Hsp_query-to>
      <Hsp_hit-from>200</Hsp_hit-from>
      <Hsp_hit-to>469</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>88</Hsp_identity>
      <Hsp_positive>137</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>287</Hsp_align-len>
      <Hsp_qseq>VGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGEL-KLIDF------GSGALLKDTVYTDFDGTRVYSPPEWIR----------YHRYHGRSAAV--WSLGVLLYDMVCGDIPFEHD------EEILRA--HVAFRK--RVSPECQELIRACLNVRPSERPLLDEILAHPWLAES</Hsp_qseq>
      <Hsp_hseq>IDEVVGQGAFATVKKAIERTTGKTFAVKIISKRKVI--GNM-DGVTRELEV------LQKLNHP--RIVRLKGFYEDTESYYMVMEFVSGG-DLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMK-----TFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGPLKDFRISEEARDFIDSLLQVDPNNRSTAAKALNHPWIKMS</Hsp_hseq>
      <Hsp_midline>+  V+G G F TV + +  +     A+K + K +V   G +  G    LEV      LQ    P   ++RL  ++E  +S+ ++ME      DL DF+   GA+ E   R   RQ++ A+++ H+ G+ HRDLK +NIL++     L K+ DF      G+G+ +K      F GT  Y  PE IR          Y   +  S+ V  WS+G L+Y ++ G +PF         ++I R   H    K  R+S E ++ I + L V P+ R    + L HPW+  S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>108.227</Hsp_bit-score>
      <Hsp_score>269</Hsp_score>
      <Hsp_evalue>2.07642e-24</Hsp_evalue>
      <Hsp_query-from>543</Hsp_query-from>
      <Hsp_query-to>1154</Hsp_query-to>
      <Hsp_hit-from>206</Hsp_hit-from>
      <Hsp_hit-to>413</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>212</Hsp_align-len>
      <Hsp_qseq>VIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHD------EEILRAHVAFRKRVSPECQELIRACLNVRPSERPLLDEILAHPWLAESESEGEPALPLAKR</Hsp_qseq>
      <Hsp_hseq>ICRLFEMCTLSNHFYMLFEYVSGGQ-LLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMIS-DSSEIKIIDFGLSNIYDSRKQLHT-FCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKIKQGKVEYPQHLSIEVISLLSKMLVVDPKRRATLKQVVEHHWMVRGFN-GPPPSYLPKR</Hsp_hseq>
      <Hsp_midline>+ RL +    ++ F ++ E     + L D+I + G++ E  AR F R +  A+ + HA  ++HRDLK ENI++     E+K+IDFG   +   +  ++T F G+  ++ PE ++ + Y G    VWS GV+L+ +VCG +PF+ +      E+I +  V + + +S E   L+   L V P  R  L +++ H W+    + G P   L KR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>98.9821</Hsp_bit-score>
      <Hsp_score>245</Hsp_score>
      <Hsp_evalue>1.6929e-22</Hsp_evalue>
      <Hsp_query-from>336</Hsp_query-from>
      <Hsp_query-to>1112</Hsp_query-to>
      <Hsp_hit-from>88</Hsp_hit-from>
      <Hsp_hit-to>344</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>128</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>270</Hsp_align-len>
      <Hsp_qseq>YRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHD------EEILRAHVAFRKRVSPECQELIRACLNVRPSER-----PLLDEILAHPWLAE</Hsp_qseq>
      <Hsp_hseq>FQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVE-------HTNDERRMLSIVSHPF--IIRMWGTFQDSQQVFMVMDYIEGG-ELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLD-KNGHIKITDFGFAKYVPDVTYT-LCGTPDYIAPEVVSTKPYN-KSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNE</Hsp_hseq>
      <Hsp_midline>+++   LG+G FG V+      +    A+K + K  + +  Q+             +++L   + P   +IR+   F+ +    ++M+  E   +LF  + +       VA+ +  +V  A+ + H+  +++RDLK ENIL+D K G +K+ DFG    + D  YT   GT  Y  PE +    Y+ +S   WS GVL+Y+M+ G  PF +       E IL A + F     P+ Q+L++  +    SER        +++  HPW  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>101.293</Hsp_bit-score>
      <Hsp_score>251</Hsp_score>
      <Hsp_evalue>2.55508e-22</Hsp_evalue>
      <Hsp_query-from>675</Hsp_query-from>
      <Hsp_query-to>1106</Hsp_query-to>
      <Hsp_hit-from>137</Hsp_hit-from>
      <Hsp_hit-to>287</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>152</Hsp_align-len>
      <Hsp_qseq>FFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFG-SGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEE------ILRAHVAFRKRVSP-ECQELIRACLNVRPSERPLLDEILAHPWL</Hsp_qseq>
      <Hsp_hseq>LFAQISGAVYYAHSMHCVHRDLKLENILLD-KNGNAKLTDFGFTRECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDAKVIPDDARDLISRLLAKNPGERPSLSQVLRHPFL</Hsp_hseq>
      <Hsp_midline> F Q+  AV + H+   +HRDLK ENIL+D K G  KL DFG +   +  T      GT VY  PE I    Y G    +WSLGV+LY ++ G +PF+ D+E      I+     +  +V P + ++LI   L   P ERP L ++L HP+L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>97.4413</Hsp_bit-score>
      <Hsp_score>241</Hsp_score>
      <Hsp_evalue>5.13414e-22</Hsp_evalue>
      <Hsp_query-from>336</Hsp_query-from>
      <Hsp_query-to>1112</Hsp_query-to>
      <Hsp_hit-from>70</Hsp_hit-from>
      <Hsp_hit-to>326</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>274</Hsp_align-len>
      <Hsp_qseq>YRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPF------EHDEEILRAHVAFRKRVSPECQELIRACL---------NVRPSERPLLDEILAHPWLAE</Hsp_qseq>
      <Hsp_hseq>FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTND-------ERRMLKLVEHPF--LIRMWGTFQDARNIFMVMDYIEGG-ELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLD-RNGHIKITDFGFAKEVQTVTWT-LCGTPDYIAPEVITTKPYN-KSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRRIGNLQSGSR----DIKAHPWFSE</Hsp_hseq>
      <Hsp_midline>+++   LG+G FG V+    + +    AIK + K +V +  Q+             +++L+    P   +IR+   F+ A +  ++M+  E   +LF  + +       VA+ +  +V+ A+ + HA  +++RDLK ENIL+D + G +K+ DFG    ++   +T   GT  Y  PE I    Y+ +S   WSLGVL+Y+M+ G  PF      +  E+IL+  V +     P+  +L+   +         N++   R    +I AHPW +E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>98.5969</Hsp_bit-score>
      <Hsp_score>244</Hsp_score>
      <Hsp_evalue>1.52918e-21</Hsp_evalue>
      <Hsp_query-from>330</Hsp_query-from>
      <Hsp_query-to>1112</Hsp_query-to>
      <Hsp_hit-from>123</Hsp_hit-from>
      <Hsp_hit-to>393</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>128</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>282</Hsp_align-len>
      <Hsp_qseq>KLYRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKD--------TVYTD-------FDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEE------ILRAHVAFRKRVSPECQELIRACLNVRPSERPLLDEILAHPWLAE</Hsp_qseq>
      <Hsp_hseq>KDFKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKV---KYVTVEKLALQKL-----NGTKGIFKLFFTFQDEASLYFLLEYAPHG-DFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLD-KNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLN-DNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKIQYAFTAGFPQIVKDLVKKLLVRDPNDRLTIKQIKAHLFFHE</Hsp_hseq>
      <Hsp_midline>K ++ G  LG G + +V            A+K + K+ +    ++     V +E + ++K+     +   G+ +L   F+   S   ++E      D    I + G+L E+ AR +  Q+++AV   H  G++HRD+K ENIL+D K  ++KL DFG+  +L +          Y D       F GT  Y  PE +    Y      +W+ G +LY M+ G  PF+   E      +++   AF        ++L++  L   P++R  + +I AH +  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>97.8265</Hsp_bit-score>
      <Hsp_score>242</Hsp_score>
      <Hsp_evalue>3.95285e-21</Hsp_evalue>
      <Hsp_query-from>330</Hsp_query-from>
      <Hsp_query-to>1112</Hsp_query-to>
      <Hsp_hit-from>177</Hsp_hit-from>
      <Hsp_hit-to>445</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>127</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>282</Hsp_align-len>
      <Hsp_qseq>KLYRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGEL--KLIDFGSGALLKDTVYT-------------DFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEE------ILRAHVAFRKRVSPECQELIRACLNVRPSERPLLDEILAHPWLAE</Hsp_qseq>
      <Hsp_hseq>KDFKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKV---KYVSIEKTALQKL---NNSPS--VVRLFSTFQDESSLYFLLEYAPNG-DFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLD---GEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLN-DSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKVQYAFTPGFPLIIRDLVKKILVKNLDRRLTISQIKEHHFFKD</Hsp_hseq>
      <Hsp_midline>K ++ G+V+G G + TV     +      A K + K+ +    ++     V +E   ++K+     SP   V+RL   F+   S   ++E      D    + + G+L E+ AR +  Q+++A+ + H+ G++HRD+K ENIL+D   GE+  KL DFG+  LL  T  +              F GT  Y  PE +    +      +W+ G +L+ M+ G  PF+   E      +++   AF        ++L++  L      R  + +I  H +  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.1301</Hsp_bit-score>
      <Hsp_score>235</Hsp_score>
      <Hsp_evalue>9.45956e-21</Hsp_evalue>
      <Hsp_query-from>342</Hsp_query-from>
      <Hsp_query-to>1106</Hsp_query-to>
      <Hsp_hit-from>17</Hsp_hit-from>
      <Hsp_hit-to>281</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>79</Hsp_identity>
      <Hsp_positive>127</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>274</Hsp_align-len>
      <Hsp_qseq>VGAVLGSGGFGTVYEG-VRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHA-CGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDT-----VYTDFDGTRVYSPPEWIRYHR-YHGRSAAVWSLGVLLYDMVCGDIPFEHDEEILRAHVAFRK-----------RVSPECQELIRACLNVRPSERPLLDEILAHPWL</Hsp_qseq>
      <Hsp_hseq>LGDTVGQGAFACVKNAHLQMDPSIILAVKFIHVPTCKKMGL--SDKDITKEVVL-----QSKCSKHPNVLRLIDCNVSKEYMWIILEMADGG-DLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENILLD-KNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQTPWELPSLENEDFVFFIENDGNLNWGPWSKIEFTHLNLLRKILQPDPNKRVTLKALKLHPWV</Hsp_hseq>
      <Hsp_midline>+G  +G G F  V    +++  ++ +A+K +      + G   S   +  EVVL     Q+  S    V+RL+D     +   +I+E  +   DLFD I     +   VA+ +F+Q+V A+ + H  CGV HRD+K ENIL+D K G LKL DFG  +  +       V  D  G+  Y  PE +     Y+     +WS+G+LL+ ++ G  P+E         V F +           ++      L+R  L   P++R  L  +  HPW+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.5153</Hsp_bit-score>
      <Hsp_score>236</Hsp_score>
      <Hsp_evalue>1.71569e-20</Hsp_evalue>
      <Hsp_query-from>276</Hsp_query-from>
      <Hsp_query-to>1112</Hsp_query-to>
      <Hsp_hit-from>392</Hsp_hit-from>
      <Hsp_hit-to>673</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>81</Hsp_identity>
      <Hsp_positive>142</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>292</Hsp_align-len>
      <Hsp_qseq>DLPGKLQINHSRERESLEKLYRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFG-SGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPF--EHDEEILRAHVAF------RKRVSPECQELIRACLNVRPSER-PLLD---EILAHPWLAE</Hsp_qseq>
      <Hsp_hseq>DILIKWTYKQTKKRHYGPQDFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEI-------AHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLD-ANGNIALCDFGLSKADLKDRTNT-FCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQK-IAFGKVKFPRDVLSQEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFAD</Hsp_hseq>
      <Hsp_midline>D+  K     +++R    + + V  +LG G FG VY+  +       A+K + K  + +  ++          +  + +L   AS  +  I  L +  +  + + ++    +  +LF  + + G  +E  A+ +  ++V A+ H H   +++RDLK ENIL+D   G + L DFG S A LKD   T F GT  Y  PE +     + +    WSLGVL+++M CG  PF  E+++++ +  +AF      R  +S E +  ++  LN  P  R   +D   E+ AHP+ A+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.2041</Hsp_bit-score>
      <Hsp_score>230</Hsp_score>
      <Hsp_evalue>3.47144e-20</Hsp_evalue>
      <Hsp_query-from>336</Hsp_query-from>
      <Hsp_query-to>1106</Hsp_query-to>
      <Hsp_hit-from>121</Hsp_hit-from>
      <Hsp_hit-to>414</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>130</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>299</Hsp_align-len>
      <Hsp_qseq>YRVGAVLGSGGFGTVYE--GVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVP-------LEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILV----------DLKRGE-------------LKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPF-EHDEEILRAHVA---------FRKRVSPECQELIRACLNVRPSERPLLDEILAHPWL</Hsp_qseq>
      <Hsp_hseq>YKLLNKIGEGAFSRVFKAVGINTDDQAPVAIKAIIKKGISSDAILKGNDRIQGSSRKKVLNEVAIHKLVSKNNPHCTKFIAFQ---ESANYYYLVTELVTGG-EIFDRIVQLTCFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLRNNTAKTPCGTIEYVASEVFTSKRYSMK-VDMWSIGCVLFTLLCGYPPFYEKNEKTLLKKISRGDYEFLAPWWDNISSGAKNAVTHLLEVDPNKRYDIDDFLNDPWL</Hsp_hseq>
      <Hsp_midline>Y++   +G G F  V++  G+   D  PVAIK + K  ++    L     +        L  V + K++      C   I      E A+ + L+ E      ++FD I +    +E +AR    QV  A++H H  G++HRD+K EN+L           D+++ +             +KL+DFG    L++       GT  Y   E     RY  +   +WS+G +L+ ++CG  PF E +E+ L   ++         +   +S   +  +   L V P++R  +D+ L  PWL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.2041</Hsp_bit-score>
      <Hsp_score>230</Hsp_score>
      <Hsp_evalue>3.88094e-20</Hsp_evalue>
      <Hsp_query-from>294</Hsp_query-from>
      <Hsp_query-to>1151</Hsp_query-to>
      <Hsp_hit-from>187</Hsp_hit-from>
      <Hsp_hit-to>495</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>81</Hsp_identity>
      <Hsp_positive>140</Hsp_positive>
      <Hsp_gaps>51</Hsp_gaps>
      <Hsp_align-len>323</Hsp_align-len>
      <Hsp_qseq>QINHSRERESLEKLYRVGAVLGSGGFGTVYEGVRLSDNLPVAIK--HVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWF-----ERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGE------------------LKLIDFGSGALLKDTVYTD-FDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHD-------EEILRAHVAFRK----RVSPECQELIRACLNVRPSERPLLDEILAHPWLAESESEGEPALPLAK</Hsp_qseq>
      <Hsp_hseq>KLNKTRPVSFFDK-YLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQND----DQKKNKQFREETNILMR-------VQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDG-ELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKKGYTSK-VDLWSAGVILYVCLCGFPPFSDQLGPPSLKEQILQAKYAFYSPYWDKIDDSVLHLISNLLVLNPDERYNIDEALNHPWFNDIQQQSSVSLELQR</Hsp_hseq>
      <Hsp_midline>++N +R     +K Y +G  LG+G +  V E         VA+K  H  ++      Q  +        +LM+            ++ LLD F     +      L++E+ +   +LF+ I  +  L +  ++  F+Q++  +++ H   ++HRD+K ENIL+++ R E                  +K+ DFG      +  +T+   GT  Y  PE +    Y  +   +WS GV+LY  +CG  PF          E+IL+A  AF      ++      LI   L + P ER  +DE L HPW  + + +   +L L +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>92.8189</Hsp_bit-score>
      <Hsp_score>229</Hsp_score>
      <Hsp_evalue>1.04752e-19</Hsp_evalue>
      <Hsp_query-from>336</Hsp_query-from>
      <Hsp_query-to>1121</Hsp_query-to>
      <Hsp_hit-from>46</Hsp_hit-from>
      <Hsp_hit-to>318</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>79</Hsp_identity>
      <Hsp_positive>131</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>288</Hsp_align-len>
      <Hsp_qseq>YRVGAVLGSGGFGTVYEG---VRLSDNLP--VAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFG-------SGALLKDTVYTDFDGTRVYSPPEWIRYHR-YHGRSAAVWSLGVLLYDMVCGDIPFEHDEE-------------ILRAHVAFRKRVSPECQELIRACLNVRPSERPLLDEILAHPWLAESES</Hsp_qseq>
      <Hsp_hseq>YIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADK--------EIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGG-EFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLD-KHENLVITDFGFVNEFFEDNELMKTSC-----GSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARLYKYITQTPLKFPEYITPIPRDLLRRILVPNPRRRINLQTIKRHVWLKPHEA</Hsp_hseq>
      <Hsp_midline>Y +G+ LG G FG V  G      S+ +P  VAIK + +D + +            E+ + +++          +I L +  + +    +++E      + + +I  +  L ES A   F Q++  V + H  G++HRDLK EN+L+D K   L + DFG          L+K +      G+  Y+ PE +   + Y  R A VWS GV+LY M+ G +P++ D E             I +  + F + ++P  ++L+R  L   P  R  L  I  H WL   E+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.5077</Hsp_bit-score>
      <Hsp_score>223</Hsp_score>
      <Hsp_evalue>1.11405e-19</Hsp_evalue>
      <Hsp_query-from>336</Hsp_query-from>
      <Hsp_query-to>1112</Hsp_query-to>
      <Hsp_hit-from>87</Hsp_hit-from>
      <Hsp_hit-to>343</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>125</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>270</Hsp_align-len>
      <Hsp_qseq>YRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHD------EEILRAHVAFRKRVSPECQELIRACLNVRPSER-----PLLDEILAHPWLAE</Hsp_qseq>
      <Hsp_hseq>FQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPF---------IIRMWGTFQDAQQIFMIMDYIEGG-ELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLD-KNGHIKITDFGFAKYVPDVTYT-LCGTPDYIAPEVVSTKPYN-KSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKE</Hsp_hseq>
      <Hsp_midline>+++   LG+G FG V+      +    A+K + K+ V    Q+       L + ++             +IR+   F+ A    +IM+  E   +LF  + +       VA+ +  +V  A+ + H+  +++RDLK ENIL+D K G +K+ DFG    + D  YT   GT  Y  PE +    Y+ +S   WS G+L+Y+M+ G  PF         E+IL A + F    + + ++L+   +    S+R        +++  HPW  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>92.4337</Hsp_bit-score>
      <Hsp_score>228</Hsp_score>
      <Hsp_evalue>1.20211e-19</Hsp_evalue>
      <Hsp_query-from>330</Hsp_query-from>
      <Hsp_query-to>1106</Hsp_query-to>
      <Hsp_hit-from>80</Hsp_hit-from>
      <Hsp_hit-to>337</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>79</Hsp_identity>
      <Hsp_positive>119</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>270</Hsp_align-len>
      <Hsp_qseq>KLYRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTDFD--GTRVYSPPEWIR-YHRYHGRSAAVWSLGVLLYDMVCGDIPFE-HDEEILRAHVAFR-------KRVSPECQELIRACLNVRPSERPLLDEILAHPWL</Hsp_qseq>
      <Hsp_hseq>KDYHRGHFLGEGGFARCFQ-IKDDSGEIFAAKTVAKASIKSEKTRKK---------LLSEIQIHKSMSHPNIVQFIDCFE-DDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFD-SNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRDKPISDEGKILIRDILSLDPIERPSLTEIMDYVWF</Hsp_hseq>
      <Hsp_midline>K Y  G  LG GGF   ++ ++       A K V K  +                 L+ ++    +     +++ +D FE  DS V I+        L + +  R  L E   R F  Q+  A+++ H+  V+HRDLK  NI  D     LK+ DFG  A+L +     +   GT  Y  PE +   H  H     +WSLGV+LY ++ G  PF+  D   +   +  R       K +S E + LIR  L++ P ERP L EI+ + W </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.1225</Hsp_bit-score>
      <Hsp_score>222</Hsp_score>
      <Hsp_evalue>4.56581e-19</Hsp_evalue>
      <Hsp_query-from>336</Hsp_query-from>
      <Hsp_query-to>1106</Hsp_query-to>
      <Hsp_hit-from>163</Hsp_hit-from>
      <Hsp_hit-to>478</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>83</Hsp_identity>
      <Hsp_positive>137</Hsp_positive>
      <Hsp_gaps>73</Hsp_gaps>
      <Hsp_align-len>323</Hsp_align-len>
      <Hsp_qseq>YRVGAVLGSGGFGTVYEGV--RLSDN-------LPVAIK-------------HVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVD-----------LKRGE----------------------LKLIDFG-SGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHD------EEILRAHVAFRK----RVSPECQELIRACLNVRPSERPLLDEILAHPWL</Hsp_qseq>
      <Hsp_hseq>YKLINKIGEGAFSKVFRAIPAKNSSNEFLTKNYKAVAIKVIKKADLSSINGDHRKKDKGKDSTKTSSRDQVLKEVALHKTV----SAGCSQIVAFID-FQETDSYYYIIQELLTGGEIFGEIVRLTYFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKNTKTPC-GTVGYTAPEVVKDEHYSMK-VDMWGIGCVLYTMLCGFPPFYDEKIDTLTEKISRGEYTFLKPWWDEISAGAKNAVAKLLELEPSKRYDIDQFLDDPWL</Hsp_hseq>
      <Hsp_midline>Y++   +G G F  V+  +  + S N         VAIK             H  KD+  +  +  S   V  EV L K V    ++ C+ ++  +D F+  DS+  I++      ++F  I      +E ++R   +Q+  AV+H H+ GV+HRD+K EN+L +           L++ +                      +KL DFG S  +      T   GT  Y+ PE ++   Y  +   +W +G +LY M+CG  PF  +      E+I R    F K     +S   +  +   L + PS+R  +D+ L  PWL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.5077</Hsp_bit-score>
      <Hsp_score>223</Hsp_score>
      <Hsp_evalue>6.84631e-19</Hsp_evalue>
      <Hsp_query-from>354</Hsp_query-from>
      <Hsp_query-to>1151</Hsp_query-to>
      <Hsp_hit-from>626</Hsp_hit-from>
      <Hsp_hit-to>886</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>124</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>278</Hsp_align-len>
      <Hsp_qseq>LGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVY--TDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEEILRAHVAFRKRVSPECQE----------LIRACLNVRPSERPLLDEILAHPWLAESESEGEPALPLAK</Hsp_qseq>
      <Hsp_hseq>IGQGASGGVYTAYEIGTNVSVAIKQMNLEK------QPKKELIINEILVMK------GSKHPNIVNFIDSYVLKGDLWVIMEYMEGGS-LTDVVT-HCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSME-GDIKLTDFGFCAQINELNLKRTTMVGTPYWMAPEVVSRKEY-GPKVDIWSLGIMIIEMIEGEPPY-LNETPLRALYLIATNGTPKLKEPENLSSSLKKFLDWCLCVEPEDRASATELLHDEYITEIAEANSSLAPLVK</Hsp_hseq>
      <Hsp_midline>+G G  G VY    +  N+ VAIK +  ++       P   L+  E+++MK       S    ++  +D +       +IME  E    L D +T    L E       R+ +  +   H+ GVLHRD+K +NIL+ ++ G++KL DFG  A + +     T   GT  +  PE +    Y G    +WSLG+++ +M+ G+ P+  +E  LRA        +P+ +E           +  CL V P +R    E+L   ++ E         PL K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.8853</Hsp_bit-score>
      <Hsp_score>211</Hsp_score>
      <Hsp_evalue>1.1706e-18</Hsp_evalue>
      <Hsp_query-from>297</Hsp_query-from>
      <Hsp_query-to>1112</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>299</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>86</Hsp_identity>
      <Hsp_positive>137</Hsp_positive>
      <Hsp_gaps>71</Hsp_gaps>
      <Hsp_align-len>321</Hsp_align-len>
      <Hsp_qseq>INHSRERESLEKLYRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERG------ALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTDFDGTRV---YSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGD--IPFEHDEEILR--------------AHVAFRKRVSPECQE------------------------LIRACLNVRPSERPLLDEILAHPWLAE</Hsp_qseq>
      <Hsp_hseq>MSSSSQFKQLEKL-------GNGTYATVYKGLNKTTGVYVALKEVKLD--SEEGT-PSTAIR--EISLMKELKHEN------IVRLYDVIHTENKLTLVFEFMD--NDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLIN-KRGQLKLGDFGLARAFGIPVNT-FSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPKYNPNIQQRPPRDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWFAE</Hsp_hseq>
      <Hsp_midline>++ S + + LEKL       G+G + TVY+G+  +  + VA+K V  D  +E G  PS A+   E+ LMK++          ++RL D     +   L+ E  +   DL  ++  R        L  ++ + F  Q+++ +  CH   +LHRDLK +N+L++ KRG+LKL DFG        V T F    V   Y  P+ +   R +  S  +WS G +L +M+ G    P  +DEE L+                V    + +P  Q+                         +   L + P  R    + L HPW AE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>89.3521</Hsp_bit-score>
      <Hsp_score>220</Hsp_score>
      <Hsp_evalue>1.36104e-18</Hsp_evalue>
      <Hsp_query-from>306</Hsp_query-from>
      <Hsp_query-to>1112</Hsp_query-to>
      <Hsp_hit-from>3</Hsp_hit-from>
      <Hsp_hit-to>295</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>138</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>304</Hsp_align-len>
      <Hsp_qseq>SRERESLEKLYRVGAVLGSGGFGTVYEGV-RLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTD-------------------FDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEEI--LRAHVAF-------------RKRVSPECQELIRACLNVRPSERPLLDEILAHPWLAE</Hsp_qseq>
      <Hsp_hseq>SRKRSPHDFIFK--EELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKV---KYVTIEKNTMNLLAQKHH---AGIIKLYYTFHDEENLYFVLDFAPGG-ELLSLLHKMGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLD-RDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQC-GYGSDIWALGCMIYQFVQGQPPFRGENELKTFEKIVALDYPWGPNNRINNSTSPINPLVINLVQKILVIEVNERISLEQIKRHPYFSK</Hsp_hseq>
      <Hsp_midline>SR+R   + +++    LG G + TV++ + + S N   AIK   K  + +  ++     V +E   M  + Q      AG+I+L   F   ++   +++      +L   + + G   +   R F  Q+++A+   H+ G++HRDLK EN+L+D + G L + DFG+ A +  ++  D                   F GT  Y  PE + Y++  G  + +W+LG ++Y  V G  PF  + E+      VA                 ++P    L++  L +  +ER  L++I  HP+ ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.9669</Hsp_bit-score>
      <Hsp_score>219</Hsp_score>
      <Hsp_evalue>2.08658e-18</Hsp_evalue>
      <Hsp_query-from>345</Hsp_query-from>
      <Hsp_query-to>1151</Hsp_query-to>
      <Hsp_hit-from>1178</Hsp_hit-from>
      <Hsp_hit-to>1455</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>131</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>285</Hsp_align-len>
      <Hsp_qseq>GAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTDFD----GTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEEILRAHVAFRKRVSPECQE------------LIRACLNVRPSERPLLDEILAHPWLAESESEGEPALPLAK</Hsp_qseq>
      <Hsp_hseq>GEMIGKGSFGAVYLCLNVTTGEMMAVKQV---EVPKYSSQNEAILSTVEA-LRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLEY-VAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLD-QDGICKISDFGISRKSKD-IYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANELLSHPFSEVNETFNFKSTRLAK</Hsp_hseq>
      <Hsp_midline>G ++G G FG VY  + ++    +A+K V    V ++       L  +E  L  +V          +++ L +  + + + L +E   A   +   I   G   E + +    QV++ + + H+ G+LHRD+K +N+L+D + G  K+ DFG     KD +Y++ D    GT  +  PE +   + +     +WSLG ++ +M  G  P+ + E +       + + +P   E             + AC  + P +RP  +E+L+HP+   +E+    +  LAK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YDL025C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:405344:407206:-1 gene:YDL025C transcript:YDL025C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RTK1 description:Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002183]</Hit_def>
  <Hit_accession>YDL025C</Hit_accession>
  <Hit_len>620</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.8113</Hsp_bit-score>
      <Hsp_score>216</Hsp_score>
      <Hsp_evalue>2.5434e-18</Hsp_evalue>
      <Hsp_query-from>318</Hsp_query-from>
      <Hsp_query-to>1106</Hsp_query-to>
      <Hsp_hit-from>296</Hsp_hit-from>
      <Hsp_hit-to>575</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>286</Hsp_align-len>
      <Hsp_qseq>ESLEKLYRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLK----DTVYTDFD--GTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPF-----------------EHDEEILRAHVAFRKRVSPECQELIRACLNVRPSERPLLDEILAHPWL</Hsp_qseq>
      <Hsp_hseq>ELLEKYGIPGRKLGEGASGSV-SVVERTDGKLFACKMFRKPHLNNEGTNQS-QLANYSKKVTTEFCIGSTLHHENIVETLDMLTEGDTYLLVMEY--APYDFFNLVMS-NLMTQDEVNCYFKQLCHGVNYLHSMGLAHRDLKLDNCVV-TKDGILKLIDFGSAVVFQYPYEDTIVKSHGIVGSDPYLAPELLKQTSYDPRVADVWSIAIIFYCMVLKRFPWKAPKKSFNSFRLFTEEPEDEDDIVRGPNKILRLLPRHSRTIIGRMLALEPKQRVLMNDVVKDDWL</Hsp_hseq>
      <Hsp_midline>E LEK    G  LG G  G+V   V  +D    A K   K  +   G   S  L      +  +           ++  LD     D+++L+ME   A  D F+ +     + +     +F+Q+   V + H+ G+ HRDLK +N +V  K G LKLIDFGS  + +    DT+       G+  Y  PE ++   Y  R A VWS+ ++ Y MV    P+                 E +++I+R      + +    + +I   L + P +R L+++++   WL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.4261</Hsp_bit-score>
      <Hsp_score>215</Hsp_score>
      <Hsp_evalue>4.21169e-18</Hsp_evalue>
      <Hsp_query-from>312</Hsp_query-from>
      <Hsp_query-to>1070</Hsp_query-to>
      <Hsp_hit-from>320</Hsp_hit-from>
      <Hsp_hit-to>586</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>85</Hsp_identity>
      <Hsp_positive>132</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>285</Hsp_align-len>
      <Hsp_qseq>ERESLEKLYRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGA--LAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDF-----GSGA---LLKDTVYTD------------FDGTRVYSPPEWIRYHRYHGRSAAV--WSLGVLLYDMVCGDIPFEHDE------EILRAHVAF--RKRVSPECQELIRACLNVRPSER</Hsp_qseq>
      <Hsp_hseq>EPQSFEKI----RLLGQGDVGKVYLVRERDTNQIFALKVLNKHEMIKRKKIK-------RVLTEQEILATSDHPF--IVTLYHSFQTKDYLYLCMEYCMGG-EFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLH-QSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVI---RGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKFPHDKEVSKNCKDLIKKLLNKNEAKR</Hsp_hseq>
      <Hsp_midline>E +S EK+     +LG G  G VY       N   A+K + K  + +  ++         V+  +++L     P   ++ L   F+  D   L ME      + F  +  R +  +AE  A+ +  +VV A+ + H  G ++RDLK ENIL+  + G + L DF      +G+    +KD+ Y D            F GT  Y  PE I   R +G +AAV  W+LG+L+Y+M+ G  PF+ D        IL   V F   K VS  C++LI+  LN   ++R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>84.7297</Hsp_bit-score>
      <Hsp_score>208</Hsp_score>
      <Hsp_evalue>1.82974e-17</Hsp_evalue>
      <Hsp_query-from>633</Hsp_query-from>
      <Hsp_query-to>1106</Hsp_query-to>
      <Hsp_hit-from>314</Hsp_hit-from>
      <Hsp_hit-to>481</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>178</Hsp_align-len>
      <Hsp_qseq>ITER--GALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDE--------EILRAHVAFRKRVSPE----------CQELIRACLNVRPSERPLLDEILAHPWL</Hsp_qseq>
      <Hsp_hseq>ISERVIGKIAESVLRG--------LSYLHERKVIHRDIKPQNILLN-EKGEIKLCDFGVSGEAVNSLAMTFTGTSFYMAPERIQGQPY-SVTCDVWSLGLTLLEVAGGRFPFESDKITQNVAPIELLTMILTFSPQLKDEPELDISWSKTFRSFIDYCLKKDARERPSPRQMLKHPWI</Hsp_hseq>
      <Hsp_midline>I+ER  G +AESV RG        + + H   V+HRD+K +NIL++ ++GE+KL DFG      +++   F GT  Y  PE I+   Y   +  VWSLG+ L ++  G  PFE D+        E+L   + F  ++  E           +  I  CL     ERP   ++L HPW+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.5741</Hsp_bit-score>
      <Hsp_score>205</Hsp_score>
      <Hsp_evalue>7.12732e-17</Hsp_evalue>
      <Hsp_query-from>336</Hsp_query-from>
      <Hsp_query-to>1142</Hsp_query-to>
      <Hsp_hit-from>24</Hsp_hit-from>
      <Hsp_hit-to>339</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>87</Hsp_identity>
      <Hsp_positive>144</Hsp_positive>
      <Hsp_gaps>69</Hsp_gaps>
      <Hsp_align-len>327</Hsp_align-len>
      <Hsp_qseq>YRVGAVLGSGGFGTVYEGVRLSD-NLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAES--------------------VARGF----FRQVVEAVRHCHACGVLHRDLKDENILV--------DLKRGE------------LKLIDFGSGALLKDTVYTD-FDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPF------EHDEEILRAH--VAFRK--RVSPECQELIRACLNVRPSERPLLDEILAHPWLAE--SESEGEPALP</Hsp_qseq>
      <Hsp_hseq>YTAEKEIGKGSFATVYRGHLTSDKSQHVAIKEVSRAKLKNKKLLEN---LEIEIAILKKIKHPH------IVGLIDCERTSTDFYLIMEYC-ALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAK-ADLWSVGTVVFEMCCGTPPFRASNHLELFKKIKRANDVITFPSYCNIEPELKELICSLLTFDPAQRIGFEEFFANKVVNEDLSSYELEDDLP</Hsp_hseq>
      <Hsp_midline>Y     +G G F TVY G   SD +  VAIK V + ++     L +   + +E+ ++KK+          ++ L+D    +  F LIME   A  DL   +  R  L E+                    + R F     +Q+  A++   +  ++HRD+K +N+L+        D K               LK+ DFG    L +T   +   G+ +Y  PE + Y +Y+ + A +WS+G ++++M CG  PF      E  ++I RA+  + F     + PE +ELI + L   P++R   +E  A+  + E  S  E E  LP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.4185</Hsp_bit-score>
      <Hsp_score>202</Hsp_score>
      <Hsp_evalue>2.06144e-16</Hsp_evalue>
      <Hsp_query-from>336</Hsp_query-from>
      <Hsp_query-to>1106</Hsp_query-to>
      <Hsp_hit-from>41</Hsp_hit-from>
      <Hsp_hit-to>313</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>128</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>288</Hsp_align-len>
      <Hsp_qseq>YRVGAVLGSGGFGTVYEG----VRLSDN----LP--VAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFG-------SGALLKDTVYTDFDGTRVYSPPEW-IRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEE-------------ILRAHVAFRKRVSPECQELIRACLNVRPSERPLLDEILAHPWL</Hsp_qseq>
      <Hsp_hseq>YILGSTLGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRK--------EVKIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEY-ACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLD-KNENLVITDFGFVNEFCSRNELMKTSC-----GSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGRLYNYINSTPLKFPDYILPIPRDLLRRMLVSDPKKRINLKQIKKHEWL</Hsp_hseq>
      <Hsp_midline>Y +G+ LG G FG V  G       S N     P  VAIK + +D ++   +         EV + +++          +++L +  + +    +++E      + + +I ++  L E  A   F Q++  V + H+ G++HRDLK EN+L+D K   L + DFG          L+K +      G+  Y+ PE  I    Y  R A +WS GV+LY ++ G +P++ D               I    + F   + P  ++L+R  L   P +R  L +I  H WL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.0333</Hsp_bit-score>
      <Hsp_score>201</Hsp_score>
      <Hsp_evalue>2.41199e-16</Hsp_evalue>
      <Hsp_query-from>324</Hsp_query-from>
      <Hsp_query-to>1106</Hsp_query-to>
      <Hsp_hit-from>19</Hsp_hit-from>
      <Hsp_hit-to>276</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>274</Hsp_align-len>
      <Hsp_qseq>LEKLYRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQ--AGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVY--TDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEEILRAHVAFRKRVSP---------ECQELIRACLNVRPSERPLLDEILAHPWL</Hsp_qseq>
      <Hsp_hseq>VSSLFKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSD------------EVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEH--CAGGSLRSLLRPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLI-TNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPY-CDVEALRAMQLIIKSKPPRLEDRSYSTSLKEFIALCLDEDPKERLSADDLLKSKFI</Hsp_hseq>
      <Hsp_midline>+  L++   V+G G FG VY+G  +      AIK +  D  ++            EV  +++ +Q  A     + + R    + +  S  +IME    A      +   G + E       R+++ A++  H   V+HRD+K  N+L+    G +KL DFG  A +  T        GT  +  PE I    Y+     +WSLG+  Y++  G+ P+  D E LRA     K   P           +E I  CL+  P ER   D++L   ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.1814</Hsp_bit-score>
      <Hsp_score>191</Hsp_score>
      <Hsp_evalue>2.38673e-15</Hsp_evalue>
      <Hsp_query-from>621</Hsp_query-from>
      <Hsp_query-to>1106</Hsp_query-to>
      <Hsp_hit-from>310</Hsp_hit-from>
      <Hsp_hit-to>488</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>181</Hsp_align-len>
      <Hsp_qseq>LFDFITERGA-LAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDE--------EILRAHVAFRKRV----------SPECQELIRACLNVRPSERPLLDEILAHPWL</Hsp_qseq>
      <Hsp_hseq>IYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLN-ENGQVKLCDFGVSGEAVNSLATTFTGTSFYMAPERIQGQPY-SVTSDVWSLGLTILEVANGKFPCSSEKMAANIAPFELLMWILTFTPELKDEPESNIIWSPSFKSFIDYCLKKDSRERPSPRQMINHPWI</Hsp_hseq>
      <Hsp_midline>++  + ERG  ++E V       V+  + + H   V+HRD+K +NIL++ + G++KL DFG      +++ T F GT  Y  PE I+   Y   ++ VWSLG+ + ++  G  P   ++        E+L   + F   +          SP  +  I  CL     ERP   +++ HPW+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.1814</Hsp_bit-score>
      <Hsp_score>191</Hsp_score>
      <Hsp_evalue>3.80685e-15</Hsp_evalue>
      <Hsp_query-from>318</Hsp_query-from>
      <Hsp_query-to>1070</Hsp_query-to>
      <Hsp_hit-from>494</Hsp_hit-from>
      <Hsp_hit-to>761</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>53</Hsp_gaps>
      <Hsp_align-len>286</Hsp_align-len>
      <Hsp_qseq>ESLEKLYRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGA--LAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTV-----------------------YTDFDGTRVYSPPEWIRYHRYHGRSAAV--WSLGVLLYDMVCGDIPFEHDE------EILRAHVAF--RKRVSPECQELIRACLNVRPSER</Hsp_qseq>
      <Hsp_hseq>QSFEKI----RLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIK-------RVLTEQEILATSNHPF--IVTLYHSFQSEDYLYLCMEYCMGG-EFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLH-QSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVI---RGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKNEVSFPNNNEISRTCKDLIKKLLTKNESKR</Hsp_hseq>
      <Hsp_midline>+S EK+     +LG G  G V+       N   A+K + KD + +  ++         V+  +++L     P   ++ L   F+  D   L ME      + F  +  R    + E  AR +  +V  A+ + H  G ++RDLK ENIL+  + G + L DF      KD+                           F GT  Y  PE I   R +G +AAV  W+LG+L+Y+M+ G  PF+ D        IL+  V+F     +S  C++LI+  L    S+R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.0258</Hsp_bit-score>
      <Hsp_score>188</Hsp_score>
      <Hsp_evalue>7.23329e-15</Hsp_evalue>
      <Hsp_query-from>351</Hsp_query-from>
      <Hsp_query-to>1112</Hsp_query-to>
      <Hsp_hit-from>349</Hsp_hit-from>
      <Hsp_hit-to>601</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>127</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>267</Hsp_align-len>
      <Hsp_qseq>VLGSGGFGTVYEGVRLSDNLPV-AIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGAL-LKDTVYTD-FDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDE-------EILRAHVAFRKRVSPECQELIRACLNVRPSER---PLLDEILAHPWLAE</Hsp_qseq>
      <Hsp_hseq>VIGKGSFGKVMQ-VRKKDTQKIYALKALRKAYIVSKCEVTH--------TLAERTVLARVD-CPFIVPLKFSFQSPEKLYLVLAFINGG-ELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDY-QGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGY-TKTVDWWTLGILLYEMMTGLPPY-YDENVPVMYKKILQQPLLFPDGFDPAAKDLLIGLLSRDPSRRLGVNGTDEIRNHPFFKD</Hsp_hseq>
      <Hsp_midline>V+G G FG V + VR  D   + A+K + K  +    ++           L ++ + A    C  ++ L   F+  +   L++       +LF  +   G  + + +R +  +++ A+   H   V++RDLK ENIL+D  +G + L DFG   L +KD   TD F GT  Y  PE +    Y  ++   W+LG+LLY+M+ G  P+ +DE       +IL+  + F     P  ++L+   L+  PS R      DEI  HP+  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.0258</Hsp_bit-score>
      <Hsp_score>188</Hsp_score>
      <Hsp_evalue>9.35242e-15</Hsp_evalue>
      <Hsp_query-from>336</Hsp_query-from>
      <Hsp_query-to>1157</Hsp_query-to>
      <Hsp_hit-from>25</Hsp_hit-from>
      <Hsp_hit-to>289</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>122</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>285</Hsp_align-len>
      <Hsp_qseq>YRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGA--LAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEEILRAHVAFR---------KRVSPECQELIRACLNVRPSERPLLDEILAHPWLAESESEGEPALPLAKRD</Hsp_qseq>
      <Hsp_hseq>YHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMA------EISLLKNLNHNNIVKYHGFIR--------KSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLS-ADNTVKLADFGVSTIVNSSALT-LAGTLNWMAPE-ILGNRGASTLSDIWSLGATVVEMLTKNPPYHN---LTDANIYYAVENDTYYPPSSFSEPLKDFLSKCFVKNMYKRPTADQLLKHVWINSTENVKVDKLNKFKED</Hsp_hseq>
      <Hsp_midline>Y +  V+G G +G VY+ +    +  VAIK V  +   E   + +      E+ L+K +         G IR         S+ L +     A      +  R +  L+E+ ++ +  Q +  +++ H  GV+HRD+K  NIL+      +KL DFG   ++  +  T   GT  +  PE I  +R     + +WSLG  + +M+  + P+ +   +  A++ +             S   ++ +  C      +RP  D++L H W+  +E+     L   K D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.3294</Hsp_bit-score>
      <Hsp_score>181</Hsp_score>
      <Hsp_evalue>1.6718e-14</Hsp_evalue>
      <Hsp_query-from>333</Hsp_query-from>
      <Hsp_query-to>962</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>222</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>235</Hsp_align-len>
      <Hsp_qseq>LYRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFIT--------ERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTDFD-GTRVYSPPEWI-----------RYHR-----YHGRSAAVWSLGVLLYDMVCGDIPF</Hsp_qseq>
      <Hsp_hseq>MYTKLRSIQSGTFSTVYKAWSTTHNRYVALKITPKYKTSE-------ANMKNEYDVMK--ILSSCNPHPNICSMLDFYTDDSYYIMVLEYCECG-DLYDFLDIAKSQGSPSSPSLIQIDMQKIIKQLCSAISFAHSLGIAHRDIKPENILLTI-NGDIKLADWGHA--IQSPKSNDFQIGTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFGDCLF</Hsp_hseq>
      <Hsp_midline>+Y     + SG F TVY+    + N  VA+K   K + +E       A +  E  +MK  + +  +P   +  +LD++     +++++E  E   DL+DF+            +L +   +   +Q+  A+   H+ G+ HRD+K ENIL+ +  G++KL D+G    ++     DF  GT  Y  PE              + R     Y+   A  WSLG  ++ ++ GD  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.9442</Hsp_bit-score>
      <Hsp_score>180</Hsp_score>
      <Hsp_evalue>2.13645e-14</Hsp_evalue>
      <Hsp_query-from>618</Hsp_query-from>
      <Hsp_query-to>1118</Hsp_query-to>
      <Hsp_hit-from>188</Hsp_hit-from>
      <Hsp_hit-to>359</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>174</Hsp_align-len>
      <Hsp_qseq>DLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALL-KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHD------EEILRAHVAFRKRVSPECQELIRACLNVRPSERPLLDEILAHPWLAESE</Hsp_qseq>
      <Hsp_hseq>EMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGF-NNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREY-DHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMPSNISQDAQDLILKLLKYDPKDRMRLGDVKMHPWILRNK</Hsp_hseq>
      <Hsp_midline>+++  +   G   + +A  +  Q+  A+ + H   ++HRD+K ENIL+      +KL DFG   +   +       GT  Y  PE +    Y   +   W+LGVL ++++ G  PFE +      + I    +     +S + Q+LI   L   P +R  L ++  HPW+  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.0998</Hsp_bit-score>
      <Hsp_score>183</Hsp_score>
      <Hsp_evalue>2.82224e-14</Hsp_evalue>
      <Hsp_query-from>351</Hsp_query-from>
      <Hsp_query-to>1112</Hsp_query-to>
      <Hsp_hit-from>352</Hsp_hit-from>
      <Hsp_hit-to>604</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>128</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>267</Hsp_align-len>
      <Hsp_qseq>VLGSGGFGTVYEGVRLSDNLPV-AIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGAL-LKDTVYTD-FDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEE-------ILRAHVAFRKRVSPECQELIRACLNVRPSER---PLLDEILAHPWLAE</Hsp_qseq>
      <Hsp_hseq>VIGKGSFGKVMQ-VRKKDTQKVYALKAIRKSYIVSKSEVTH--------TLAERTVLARVD-CPFIVPLKFSFQSPEKLYFVLAFINGG-ELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDY-QGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGY-TKAVDWWTLGVLLYEMLTGLPPY-YDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSRDPTRRLGYNGADEIRNHPFFSQ</Hsp_hseq>
      <Hsp_midline>V+G G FG V + VR  D   V A+K + K  +    ++           L ++ + A    C  ++ L   F+  +    ++       +LF  + + G    S AR +  +++ A+ + H   V++RDLK ENIL+D  +G + L DFG   L +KD   TD F GT  Y  PE +    Y  ++   W+LGVLLY+M+ G  P+ +DE+       IL+  + F      + ++L+   L+  P+ R      DEI  HP+ ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>7.56162e-14</Hsp_evalue>
      <Hsp_query-from>246</Hsp_query-from>
      <Hsp_query-to>1112</Hsp_query-to>
      <Hsp_hit-from>162</Hsp_hit-from>
      <Hsp_hit-to>468</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>137</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>323</Hsp_align-len>
      <Hsp_qseq>LAHMCSPATVDLPGKLQINHSRERESLEKLYRVGAVLGSGGFGTVYEGVRLSDNLPVAIKH--VGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERA---DSFVLIMERPEAAR-----DLFDFITERGALAESVARGFFRQ---------VVEAVRHCH-ACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEEILRAHVAFRKRV--------------SPECQELIRACLNVRPSERPLLDEILAHPWLAE</Hsp_qseq>
      <Hsp_hseq>LEESLSPAAADLKDTLSGTSNGNYIQLQDLVQLGKI-GAGNSGTVVKALHVPDSKIVAKKTIPVEQNNSTIINQLVR------ELSIVKNV-----KPHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILSVYKRFVQRGTV--SSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSK-GQIKLCDFGVSKKLINSIADTFVGTSTYMSPERIQGNVYSIK-GDVWSLGLMIIELVTGEFPLGGHNDTPDGILDLLQRIVNEPSPRLPKDRIYSKEMTDFVNRCCIKNERERSSIHELLHHDLIMK</Hsp_hseq>
      <Hsp_midline>L    SPA  DL   L    +     L+ L ++G + G+G  GTV + + + D+  VA K   V ++  T   QL        E+ ++K V      P   +I     +      +  +++ME  +         ++    +RG +  S  + +F +         V+  + H +    ++HRD+K  N+L++ K G++KL DFG    L +++   F GT  Y  PE I+ + Y  +   VWSLG+++ ++V G+ P     +     +   +R+              S E  + +  C      ER  + E+L H  + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>1.15074e-13</Hsp_evalue>
      <Hsp_query-from>630</Hsp_query-from>
      <Hsp_query-to>1106</Hsp_query-to>
      <Hsp_hit-from>544</Hsp_hit-from>
      <Hsp_hit-to>712</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>FITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALL-----KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEEILRAHVAFRKRVSPEC--------QELIRACLNVRPSERPLLDEILAHPWL</Hsp_qseq>
      <Hsp_hseq>MLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIK-GCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAK-ADIWSTGCVVIEMFTGKHPFP-DFSQMQAIFKIGTNTTPEIPSWATSEGKNFLRKAFELDYQYRPSALELLQHPWL</Hsp_hseq>
      <Hsp_midline> +   G   ES+   F RQ++  V + H   ++HRD+K  NIL+D+K G +K+ DFG    L     K        G+  +  PE ++      + A +WS G ++ +M  G  PF  D   ++A        +PE         +  +R    +    RP   E+L HPWL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.559</Hsp_bit-score>
      <Hsp_score>179</Hsp_score>
      <Hsp_evalue>1.30584e-13</Hsp_evalue>
      <Hsp_query-from>348</Hsp_query-from>
      <Hsp_query-to>1160</Hsp_query-to>
      <Hsp_hit-from>1038</Hsp_hit-from>
      <Hsp_hit-to>1325</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>127</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>302</Hsp_align-len>
      <Hsp_qseq>AVLGSGGFGTVYEGVRLSDNLPVAIKHVG-KDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSG--------ALLKDTVYTDFD----------GTRVYSPPEWIRYHRYHGRSAA--VWSLGVLLYDMVCGDIPFEH--DEEILRAHVAF--------RKRVSPECQELIRACLNVRPSERPLLDEILAHPWLAESESEGEPALPLAKRDQ</Hsp_qseq>
      <Hsp_hseq>SFIGGGTFGQVYSAINLENGEILAVKEIKIHDTTTMKKIFP---LIKEEMTVLEMLNHPNIVQYYGVEV------HRDKVNIFMEYCEGG-SLASLLDHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDF-NGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPWSNLDNEWAIMYHVAAGRIPQLPNRDEMTAAGRAFLERCLVQDPTMRATAVELLIDPWMIQIR---EIAFGNSEKDQ</Hsp_hseq>
      <Hsp_midline>+ +G G FG VY  + L +   +A+K +   D  T     P   L+  E+ +++ +         GV          D   + ME  E    L   +       E V + +  +++E + + H  GV+HRD+K ENIL+D   G +K +DFG+           +++    DF           GT +Y  PE I      G+  A  VW+LG ++ +M  G  P+ +  +E  +  HVA         R  ++   +  +  CL   P+ R    E+L  PW+ +     E A   +++DQ</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YMR291W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:852630:854390:1 gene:YMR291W transcript:YMR291W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TDA1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000004905]</Hit_def>
  <Hit_accession>YMR291W</Hit_accession>
  <Hit_len>586</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>2.19057e-13</Hsp_evalue>
      <Hsp_query-from>354</Hsp_query-from>
      <Hsp_query-to>1112</Hsp_query-to>
      <Hsp_hit-from>45</Hsp_hit-from>
      <Hsp_hit-to>353</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>125</Hsp_positive>
      <Hsp_gaps>58</Hsp_gaps>
      <Hsp_align-len>310</Hsp_align-len>
      <Hsp_qseq>LGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGAL-----VPLEVVLMKKVLQAGASPCAG---VIRLLDWFERADSFVLIMERPEAARDLFDFITERGALA-ESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGE---------------------LKLIDFGSGA---LLKDTVYTDFDGTRVYSPPEWIRYH-------------RYHGRSAAVWSLGVLLYDMVCGDIPFE--HDEEILRA------HVAFRKRVSPECQE---LIRACLNVRPSERPLLDEILAHPWLAE</Hsp_qseq>
      <Hsp_hseq>LGDGNFSVVKECMNIHTKDLYAMKLIKKQTVKNKIQLIQREFDLLRSISEKIRDMEKKNEHSLDIFEGHHHILQLFDYFETADNIVLITQLCQKG-DLYEKIVENQCLDLETQVTSYCACLVSVLEFLHSQGIVHRDLKAENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLVLADFGLAAEYNTSKVNSLKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGCPVDIWALGVLTYFMAFGYTPFDCTTDDETLECISKCDYYVDEQMMHDPKYEQFWNFVQCCFTIDPAVRRSAKNLKQHPFIKD</Hsp_hseq>
      <Hsp_midline>LG G F  V E + +      A+K + K  V    QL          +  ++  M+K  +       G   +++L D+FE AD+ VLI +  +   DL++ I E   L  E+    +   +V  +   H+ G++HRDLK EN+L  L+  E                     L L DFG  A     K     +F GT  Y  PE ++                 +G    +W+LGVL Y M  G  PF+   D+E L        +V  +    P+ ++    ++ C  + P+ R     +  HP++ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.4034</Hsp_bit-score>
      <Hsp_score>176</Hsp_score>
      <Hsp_evalue>2.39068e-13</Hsp_evalue>
      <Hsp_query-from>354</Hsp_query-from>
      <Hsp_query-to>1112</Hsp_query-to>
      <Hsp_hit-from>1272</Hsp_hit-from>
      <Hsp_hit-to>1560</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>122</Hsp_positive>
      <Hsp_gaps>60</Hsp_gaps>
      <Hsp_align-len>301</Hsp_align-len>
      <Hsp_qseq>LGSGGFGTVYEGVRLSDNLPVAIKHVG-KDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALA-ESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALL----------------------------------KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAA--VWSLGVLLYDMVCGDIPFEH--DEEILRAHVA--------FRKRVSPECQELIRACLNVRPSERPLLDEILAHPWLAE</Hsp_qseq>
      <Hsp_hseq>IGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFP---LIKEEMSVLEILNHPNIVSYYGVEV------HRDKVNIFMEYCEGGS--LAALLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDF-NGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPWANLDNEWAIMYHVAAGHTPQFPTKDEVSSAGMKFLERCLIQNPSKRASAVELLMDPWIVQ</Hsp_hseq>
      <Hsp_midline>+G G FG VY  V L +   +A+K +  +D  +     P   L+  E+ +++ +         GV          D   + ME  E        + E G +  E V + +  Q++E + + H  G++HRD+K ENIL+D   G +K +DFG+   +                                   +    D  GT +Y  PE I      G+  A  VWSLG ++ +M+ G  P+ +  +E  +  HVA         +  VS    + +  CL   PS+R    E+L  PW+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>5.40261e-13</Hsp_evalue>
      <Hsp_query-from>336</Hsp_query-from>
      <Hsp_query-to>1142</Hsp_query-to>
      <Hsp_hit-from>13</Hsp_hit-from>
      <Hsp_hit-to>326</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>79</Hsp_identity>
      <Hsp_positive>129</Hsp_positive>
      <Hsp_gaps>65</Hsp_gaps>
      <Hsp_align-len>324</Hsp_align-len>
      <Hsp_qseq>YRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTV------------YTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYD------------------MVCGDIPFEHDEEILRAHVAFRK--------------------RVSPECQELIRACLNVRPSERPLLDEILAHPWLA-----ESESEGEPALP</Hsp_qseq>
      <Hsp_hseq>FQLKSLLGEGAYGVVCSATHKPTGEIVAIKKI------EPFDKPLFALRTLREIKILKHFKHENIITIFNIQRPDSFENFNEVYIIQELMQT--DLHRVISTQ-MLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLIN-SNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHSDNDLRCIESPRAREYIKSLPMYPAAPLEKMFPRVNPKGIDLLQRMLVFDPAKRITAKEALEHPYLQTYHDPNDEPEGEPIPP</Hsp_hseq>
      <Hsp_midline>+++ ++LG G +G V           VAIK +      E    P  AL  L  + + K  +         I+  D FE  +   +I E  +   DL   I+ +  L++   + F  Q + AV+  H   V+HRDLK  N+L++    +LK+ DFG   ++ ++              T++  TR Y  PE +     + R+  VWS G +L +                  ++ G I   H +  LR   + R                     RV+P+  +L++  L   P++R    E L HP+L        E EGEP  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>6.06966e-13</Hsp_evalue>
      <Hsp_query-from>327</Hsp_query-from>
      <Hsp_query-to>1103</Hsp_query-to>
      <Hsp_hit-from>313</Hsp_hit-from>
      <Hsp_hit-to>589</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>283</Hsp_align-len>
      <Hsp_qseq>EKLYRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDR----VTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADS-FVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTDFD------GTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGD---IPFEHDEEILRAHVAFRKRVS----------PECQELIRACLNVRPSERPLLDEILAHPW</Hsp_qseq>
      <Hsp_hseq>EKYGRCQEVLGKGAFGVV----RICQKKNVSSQDGNKSEKLYAVKEFKRRTSESAEKYSKRLTSEFCISSSLHHTNIVTTLDLFQDAKGEYCEVMEYC-AGGDLFTLVVAAGKLEYMEADCFFKQLIRGVVYMHEMGVCHRDLKPENLLL-THDGVLKITDFGNSECFKMAWEKNIHLSGGVCGSSPYIAPEEYIKEEFDPRPVDIWACGVIYMAMRTGRQLWSSAEKDDPFYMNYLKGRKEKGGYEPIESLKRARCRNVIYSMLDPVPYRRINGKQILNSEW</Hsp_hseq>
      <Hsp_midline>EK  R   VLG G FG V    R+     V+ +   K      V E+ +  S +       L  +   + +     ++  LD F+ A   +  +ME   A  DLF  +   G L    A  FF+Q++  V + H  GV HRDLK EN+L+    G LK+ DFG+    K     +        G+  Y  PE      +  R   +W+ GV+   M  G       E D+     ++  RK               C+ +I + L+  P  R    +IL   W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YDL028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:400997:403291:-1 gene:YDL028C transcript:YDL028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MPS1 description:Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]</Hit_def>
  <Hit_accession>YDL028C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>1.33004e-12</Hsp_evalue>
      <Hsp_query-from>336</Hsp_query-from>
      <Hsp_query-to>1106</Hsp_query-to>
      <Hsp_hit-from>440</Hsp_hit-from>
      <Hsp_hit-to>716</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>81</Hsp_identity>
      <Hsp_positive>133</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>292</Hsp_align-len>
      <Hsp_qseq>YRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFV-LIMERPEAARDLFDFITERGA--LAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFG-SGALLKDTV--YTDFD-GTRVYSPPEWIRYHRYH--------------GRSAAVWSLGVLLYDMVCGDIP---FEHDEEILR-----------AHVAFRKRVSPECQELIRACLNVRPSERPLLDEILAHPWL</Hsp_qseq>
      <Hsp_hseq>YEKIELLGRGGSSRVYK-VKGSGNRVYALKRVSFDAFDD----SSIDGFKGEIELLEKLKDQKR-----VIQLLDY-EMGDGLLYLIMECGD--HDLSQILNQRSGMPLDFNFVRFYTKEMLLCIKVVHDAGIVHSDLKPANFV--LVKGILKIIDFGIANAVPEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYGKPPYGSFQGQNRLLAIMNPDVKIPFPEHTSNNEKIPKSAIELMKACLYRNPDKRWTVDKVLSSTFL</Hsp_hseq>
      <Hsp_midline>Y    +LG GG   VY+ V+ S N   A+K V  D   +     S      E+ L++K+          VI+LLD+ E  D  + LIME  +   DL   + +R    L  +  R + ++++  ++  H  G++H DLK  N +  L +G LK+IDFG + A+ + TV  Y +   GT  Y  PE +    Y               GR + +WS G ++Y M+ G  P   F+    +L             H +  +++     EL++ACL   P +R  +D++L+  +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>2.00396e-12</Hsp_evalue>
      <Hsp_query-from>264</Hsp_query-from>
      <Hsp_query-to>950</Hsp_query-to>
      <Hsp_hit-from>26</Hsp_hit-from>
      <Hsp_hit-to>236</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>238</Hsp_align-len>
      <Hsp_qseq>PATVDLPGKLQINHSRERESLEKLYRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADS-----FVLIME-RPEA-ARDLFDFITERGALAESVARGFFRQVVEAVRHCHA-CGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDT-VYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCG</Hsp_qseq>
      <Hsp_hseq>PPTIDPNDPVQIS-----------FPTTEVVGHGSFGVVFATVIQETNEKVAIKKVLQDKRFKNREL--------EIMKMLSHI--------NIIDLKYFFYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLG</Hsp_hseq>
      <Hsp_midline>P T+D    +QI+           +    V+G G FG V+  V    N  VAIK V +D+  +  +L        E++ M   +         +I L  +F   DS       LI+E  P++  + L  F+ +R  ++    + +  Q+ +++ + H    V HRD+K +N+LVD +   LKL DFGS   LK T     +  +R Y  PE I     +     +WS G ++ +++ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YIL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:287790:288908:-1 gene:YIL035C transcript:YIL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA1 description:Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000001297]</Hit_def>
  <Hit_accession>YIL035C</Hit_accession>
  <Hit_len>372</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>4.40835e-12</Hsp_evalue>
      <Hsp_query-from>618</Hsp_query-from>
      <Hsp_query-to>1103</Hsp_query-to>
      <Hsp_hit-from>156</Hsp_hit-from>
      <Hsp_hit-to>319</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>164</Hsp_align-len>
      <Hsp_qseq>DLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLK-DTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEEILRAHVAFRKRV-SPECQELIRACLNVRPSERPLLDEILAHPW</Hsp_qseq>
      <Hsp_hseq>DNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLLKYEITLPREFYDMDQYIRKPW</Hsp_hseq>
      <Hsp_midline>D  DF      L +   R +  ++++A+ +CH+ G++HRD+K  N+++D K  +L+LID+G       +  Y     +R +  PE +  +R +  S  +WS G +L  M+    PF H        V   K + + + ++ +       P E   +D+ +  PW</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>5.42407e-12</Hsp_evalue>
      <Hsp_query-from>354</Hsp_query-from>
      <Hsp_query-to>1019</Hsp_query-to>
      <Hsp_hit-from>189</Hsp_hit-from>
      <Hsp_hit-to>400</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>LGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGA-LAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTV-YTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEEILRAHVAFRKRVSP</Hsp_qseq>
      <Hsp_hseq>VGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREG--------FPITSIREIKLLQSFDHPNVSTIKEI-MVESQKTVYMIFEY--ADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILID-NQGNLKITDFGLARKMNSRADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTP</Hsp_hseq>
      <Hsp_midline>+G G +G VY+    +    VA+K +      E          P+  +   K+LQ+   P    I+ +   E   +  +I E   A  DL   +  +   ++ S  +  F+Q++  + + H   +LHRD+K  NIL+D  +G LK+ DFG    +     YT+   T  Y PPE +     +G    +W  G LL ++      F+   E+ +    F+   +P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>8.23796e-12</Hsp_evalue>
      <Hsp_query-from>267</Hsp_query-from>
      <Hsp_query-to>1112</Hsp_query-to>
      <Hsp_hit-from>330</Hsp_hit-from>
      <Hsp_hit-to>625</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>127</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>309</Hsp_align-len>
      <Hsp_qseq>ATVDLPGKLQI--------NHSRERESLEKLYRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAAR--DLFDFITERGALAESVARGFFRQVVEAVRHC-HACGVLHRDLKDENILVDLKRGELKLIDFG-SGALLKDTVYTDFDGTRVYSPPEWIRY----HRYHGRSAAVWSLGVLLYDMVCGDIPF--EHDEEILRAHVAF---------RKRVSPECQELIRACLNVRPSERPLLDEILAHPWLAE</Hsp_qseq>
      <Hsp_hseq>GSLNFAGKLSLSSKGIDFSNGSSSRITLDELEFLDE-LGHGNYGNVSKVLHKPTNVIMATKEV---------RLELDEAKFRQILMELEVLHKCNSPY--IVDFYGAFFIEGAVYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSANQGTVKLCDFGVSGNLVASLAKTNI-GCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYPPETYDNIFSQLSAIVDGPPPRLPSDKFSSDAQDFVSLCLQKIPERRPTYAALTEHPWLVK</Hsp_hseq>
      <Hsp_midline> +++  GKL +        N S  R +L++L  +   LG G +G V + +    N+ +A K V         +L        ++++  +VL    SP   ++     F    +  + ME  +      ++D  +E G + E         V+  ++       ++HRD+K  NIL    +G +KL DFG SG L+     T+  G + Y  PE I+        +   + +WSLG+ + +M  G  P+  E  + I     A            + S + Q+ +  CL   P  RP    +  HPWL +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>8.58623e-12</Hsp_evalue>
      <Hsp_query-from>351</Hsp_query-from>
      <Hsp_query-to>977</Hsp_query-to>
      <Hsp_hit-from>829</Hsp_hit-from>
      <Hsp_hit-to>1029</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>214</Hsp_align-len>
      <Hsp_qseq>VLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVY-----TDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEE</Hsp_qseq>
      <Hsp_hseq>VLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIES-ARAEKKVFLL-----ATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQR--LSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILL-TPEGHIKIADYG---LCKDEMWYGNRTSTFCGTPEFMAPEILKEQEY-TKAVDWWAFGVLLYQMLLCQSPFSGDDE</Hsp_hseq>
      <Hsp_midline>VLG G FG V      + +   AIK + KD + +   + S A    +V L+     A  +    +  L   F+  +     ME       ++    +R  L+   A+ +  +V+ A+++ H  GV++RDLK ENIL+    G +K+ D+G   L KD ++     + F GT  +  PE ++   Y  ++   W+ GVLLY M+    PF  D+E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YDL214C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:74446:76545:-1 gene:YDL214C transcript:YDL214C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR2 description:Serine/threonine protein kinase; inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance; PRR2 has a paralog, NPR1, that arose from the whole genome duplication [Source:SGD;Acc:S000002373]</Hit_def>
  <Hit_accession>YDL214C</Hit_accession>
  <Hit_len>699</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>1.11662e-11</Hsp_evalue>
      <Hsp_query-from>324</Hsp_query-from>
      <Hsp_query-to>968</Hsp_query-to>
      <Hsp_hit-from>356</Hsp_hit-from>
      <Hsp_hit-to>566</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>LEKLYR-VGAVLGSGGFGTVYEGVRLSDNLPVAIKHV--GKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTDFD------GTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEH</Hsp_qseq>
      <Hsp_hseq>VSRKYRDLDVVLGEGSGGKVKLVQRVLDNKVFALKEYRSKKKRESERKYIKN---------IISEYCIASTLKNPNICETLEILYEKGKIFQILEYCEY--DLFSLVMSEKMHYEEIC-CLFKQLINGVKYLHDIGLSHRDLKLDNCVV-TRRGILKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFYFNEYDPRALDVWSVGIIFFCMITRRFPWKY</Hsp_hseq>
      <Hsp_midline>+ + YR +  VLG G  G V    R+ DN   A+K     K R +E   + +         ++ +   A       +   L+          I+E  E   DLF  +       E +    F+Q++  V++ H  G+ HRDLK +N +V  +RG LKLIDFG+ ++    + +         G+  Y  PE   ++ Y  R+  VWS+G++ + M+    P+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>1.14847e-11</Hsp_evalue>
      <Hsp_query-from>354</Hsp_query-from>
      <Hsp_query-to>1019</Hsp_query-to>
      <Hsp_hit-from>13</Hsp_hit-from>
      <Hsp_hit-to>224</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>225</Hsp_align-len>
      <Hsp_qseq>LGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGAL-AESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEEILRAHVAFRKRVSP</Hsp_qseq>
      <Hsp_hseq>VGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDG--------LDMSAIREVKYLQEMQHP--NVIELIDIFMAYDNLNLVLEF--LPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFS-PDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTP</Hsp_hseq>
      <Hsp_midline>+G G +  VY G + S    +AIK +      +         + +  +   K LQ    P   VI L+D F   D+  L++E      DL   I ++  L   +  + +    +  V HCH   +LHRDLK  N+L     G++K+ DFG    +     + T    TR Y  PE +   +++  +  +WS+GV+  +++          ++ +  V FR   +P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>1.47772e-11</Hsp_evalue>
      <Hsp_query-from>306</Hsp_query-from>
      <Hsp_query-to>986</Hsp_query-to>
      <Hsp_hit-from>28</Hsp_hit-from>
      <Hsp_hit-to>248</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>240</Hsp_align-len>
      <Hsp_qseq>SRERESLEKLYRVGAVLGSGGFGTVYEGVRLSDNL----PVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFER---ADSFV---LIME-RPEAAR-DLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLK-DTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEEILR</Hsp_qseq>
      <Hsp_hseq>NNTRRMLVKEYRK---IGRGAFGTVVQAYLTQDKKNWLGPFAIKKVPAHTEYKSREL--------------QILRIADHP--NIVKLQYFFTHLSPQDNKVYQHLAMECLPETLQIEINRYVTNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSISYICSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQ</Hsp_hseq>
      <Hsp_midline>+  R  L K YR    +G G FGTV +     D      P AIK V      +  +L              ++L+    P   +++L  +F      D+ V   L ME  PE  + ++  ++T +  +     R +  Q+   + + H  GV HRD+K  N+LVD + G LK+ DFGS   L+ +     +  +R Y  PE I     +     +W LG ++ +M+ G   F+  E +L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YOR061W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:441534:442553:1 gene:YOR061W transcript:YOR061W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA2 description:Alpha&apos; catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000005587]</Hit_def>
  <Hit_accession>YOR061W</Hit_accession>
  <Hit_len>339</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>2.08588e-11</Hsp_evalue>
      <Hsp_query-from>336</Hsp_query-from>
      <Hsp_query-to>962</Hsp_query-to>
      <Hsp_hit-from>50</Hsp_hit-from>
      <Hsp_hit-to>243</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>214</Hsp_align-len>
      <Hsp_qseq>YRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAG--VIRLLDWFERADSFV--LIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTV-YTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPF</Hsp_qseq>
      <Hsp_hseq>YEIINKIGRGKYSEVFSGRCIVNNQKCVIK----------------VLKPVKMKKIYRELKILTNLTGGPNVVGLYDIVQDADSKIPALIFEEIKNV----DFRTLYPTFKLPDIQYYFTQLLIALDYCHSMGIMHRDVKPQNVMIDPTERKLRLIDWGLAEFYHPGVDYNVRVASRYHKGPELLVNLNQYDYSLDLWSVGCMLAAIVFKKEPF</Hsp_hseq>
      <Hsp_midline>Y +   +G G +  V+ G  + +N    IK                 L P+++  + + L+   +   G  V+ L D  + ADS +  LI E  +      DF T          + +F Q++ A+ +CH+ G++HRD+K +N+++D    +L+LID+G        V Y     +R +  PE +     +  S  +WS+G +L  +V    PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>2.24325e-11</Hsp_evalue>
      <Hsp_query-from>309</Hsp_query-from>
      <Hsp_query-to>1034</Hsp_query-to>
      <Hsp_hit-from>32</Hsp_hit-from>
      <Hsp_hit-to>279</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>264</Hsp_align-len>
      <Hsp_qseq>RERESLEKLYRVGAVLGSGGFGTVYEGVRLSDNL----PVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFER-----------ADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKD-TVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHD------EEILRAHVAFRKRVSPECQEL</Hsp_qseq>
      <Hsp_hseq>KNRQKSKMYVREGKRIGHGSFGTVTQSILSSNSIEWLGPYAIKRVVK----------SPKVQSLEL----EILQNIRHP--NLVTLEFFFESHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGIAKVCDFGSAQRLDDNTELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPLFKGDSANSQLEEIAKLLGRFPKSSIKNSQEL</Hsp_hseq>
      <Hsp_midline>+ R+  +   R G  +G G FGTV + +  S+++    P AIK V K          S  +  LE+    ++LQ    P   ++ L  +FE              +FV+       + ++ ++      +     + +  Q++ A+   H+  + H DLK  NIL+    G  K+ DFGS   L D T    +  +R Y  PE +   + +     +WSLG ++ +M+ G   F+ D      EEI +    F K      QEL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YJL165C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:106894:109461:-1 gene:YJL165C transcript:YJL165C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HAL5 description:Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters; HAL5 has a paralog, KKQ8, that arose from the whole genome duplication [Source:SGD;Acc:S000003701]</Hit_def>
  <Hit_accession>YJL165C</Hit_accession>
  <Hit_len>855</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>2.40136e-11</Hsp_evalue>
      <Hsp_query-from>540</Hsp_query-from>
      <Hsp_query-to>1118</Hsp_query-to>
      <Hsp_hit-from>602</Hsp_hit-from>
      <Hsp_hit-to>841</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>51</Hsp_gaps>
      <Hsp_align-len>242</Hsp_align-len>
      <Hsp_qseq>GVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAES----------VARG------------FFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDT--VYTDFD----GTRVY-SPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGD----IPFEHDEEILRAHVAFRK------------RVSPECQELIRACL----NVRPSERPLLDEILAHPWLAESE</Hsp_qseq>
      <Hsp_hseq>NILKILDLMEYSNSFVEVMEFC-ASGDLYSLLTRNNISNESNNGSSRLIQTVKEGSGSPLHPLEADCFMKQLLNGVQYMHDHGIAHCDLKPENILFQ-PNGLLKICDFGTSSVFQTAWEKHVHFQSGAMGSEPYVAPEEFIRDAEYDPRLVDCWSCGIVYCTMVMGQYLWKIAIPEKDSLFKSFLSEIKDDGQFYLFEELRHVSSELNRLRKIALYRTFQVDPTKRITIEQLLQSSWMRKTK</Hsp_hseq>
      <Hsp_midline> ++++LD  E ++SFV +ME   A+ DL+  +T      ES          V  G            F +Q++  V++ H  G+ H DLK ENIL     G LK+ DFG+ ++ +     +  F     G+  Y +P E+IR   Y  R    WS G++   MV G     I     + + ++ ++  K             VS E   L +  L     V P++R  ++++L   W+ +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>3.6387e-11</Hsp_evalue>
      <Hsp_query-from>354</Hsp_query-from>
      <Hsp_query-to>1022</Hsp_query-to>
      <Hsp_hit-from>14</Hsp_hit-from>
      <Hsp_hit-to>232</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>230</Hsp_align-len>
      <Hsp_qseq>LGSGGFGTVYEGVRLSDNLPVAIKHVGKDRV-TEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFER-ADSFVLIMERPEA-ARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFG----SGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEEILRAHVAFRKRVSPE</Hsp_qseq>
      <Hsp_hseq>VGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAI--REISLLKELKDDN------IVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLIN-KDGNLKLGDFGLARAFGVPLR--AYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPN</Hsp_hseq>
      <Hsp_midline>+G G +G VY+ + L       +  + K R+ +E   +PS A+   E+ L+K++          ++RL D     A    L+ E  +   +   + I +   L   + + F  Q+ + + +CH+  +LHRDLK +N+L++ K G LKL DFG     G  L+   YT    T  Y  PE +   + +      WS+G +  +M      F  D EI +    FR   +P </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>5.75412e-11</Hsp_evalue>
      <Hsp_query-from>309</Hsp_query-from>
      <Hsp_query-to>1106</Hsp_query-to>
      <Hsp_hit-from>9</Hsp_hit-from>
      <Hsp_hit-to>272</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>120</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>279</Hsp_align-len>
      <Hsp_qseq>RERESLEKLYRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMER--PEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTD-FDGTRVYSPPEWI--RYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEEILRAHVAFRKRVSPECQ--------ELIRACLNVRPSERPLLDEILAHPWL</Hsp_qseq>
      <Hsp_hseq>RSRTPPSKLYSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDV-----------SMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVS-FIIHEVTLGLKYLHEQRKIHRDIKAANILLN-EEGMVKLGDFGVSGHIRSTLKRDTFVGTPYWMAPEVVCCEVDGYNEK-ADIWSLGITTYELLKGLPPLSKYDP-MKVMTNLPKRKPPKLQGPFSDAAKDFVAGCLVKTPADRPSAYNLLSFEFV</Hsp_hseq>
      <Hsp_midline>R R    KLY + + +G G FG VY+ V       VAIK V  +   E  +L +  +  L  +    +    A+    V           S  ++ME     +  DL       G   E V+     +V   +++ H    +HRD+K  NIL++ + G +KL DFG    ++ T+  D F GT  +  PE +      Y+ + A +WSLG+  Y+++ G  P    +  ++      KR  P+ Q        + +  CL   P++RP    +L+  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>7.03631e-11</Hsp_evalue>
      <Hsp_query-from>336</Hsp_query-from>
      <Hsp_query-to>950</Hsp_query-to>
      <Hsp_hit-from>13</Hsp_hit-from>
      <Hsp_hit-to>222</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>223</Hsp_align-len>
      <Hsp_qseq>YRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLD-----WFERADSFVLIMERPEAARDLFDFITERGA----LAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDT---------VYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCG</Hsp_qseq>
      <Hsp_hseq>YKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKI---------QPFSKKLFVTRTIREIKLLRYFHE-HENIISILDKVRPVSIDKLNAVYLVEELMET--DLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLN-SNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSG</Hsp_hseq>
      <Hsp_midline>Y++  ++G G +GTV   +     + VAIK +         Q  S  L     +   K+L+        +I +LD       ++ ++  L+ E  E   DL   I  + +    L++   + F  Q++ A++  H+  V+HRD+K  N+L++    +LK+ DFG    L  +           T++  TR Y  PE +   + +  +  +WS G +L +MV G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>1.01119e-10</Hsp_evalue>
      <Hsp_query-from>357</Hsp_query-from>
      <Hsp_query-to>1109</Hsp_query-to>
      <Hsp_hit-from>367</Hsp_hit-from>
      <Hsp_hit-to>640</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>122</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>276</Hsp_align-len>
      <Hsp_qseq>GSGGFGTVYEGVRL---SDNLPVAIKHVGKDRVTEWGQLPSGALV--PLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFV-LIMERPEAA--RDLFDFITERGA------LAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEEILRAHVAFR---------KRVSPECQELIRACLNVRPSERPLLDEILAHPWLA</Hsp_qseq>
      <Hsp_hseq>GQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQPKKQLIMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLN-SQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEK-VDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANNGSPKLRHPESVSKQTKQFLDACLQVNVESRASVRKLLTFEFLS</Hsp_hseq>
      <Hsp_midline>G G  G VY   R+    +N P  +K      V E   +    L   P + ++M ++L    S    ++  L+ +   D  + +IME  E     D+ D +           L E+      ++  + ++  H   ++HRD+K +NIL++  +G +K+ DFG    L  K +      GT  +  PE +    Y  +   VWSLG++L +M+ G+ P+ +++ +   ++            + VS + ++ + ACL V    R  + ++L   +L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>1.1413e-10</Hsp_evalue>
      <Hsp_query-from>540</Hsp_query-from>
      <Hsp_query-to>962</Hsp_query-to>
      <Hsp_hit-from>213</Hsp_hit-from>
      <Hsp_hit-to>362</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>153</Hsp_align-len>
      <Hsp_qseq>GVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFG-SGALLKDTVYTDFD-----------GTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPF</Hsp_qseq>
      <Hsp_hseq>NIVKLFYSFHDNSKLYLLLQYIPGG-ELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLN-QRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPE-ILLGKAYSQNCDWYSLGCLLYDMLVGKPPY</Hsp_hseq>
      <Hsp_midline> +++L   F       L+++      +LF  + E G L E+    +  ++  A+R  H  GV++RDLK EN L++ +RG L L DFG S     D+   + D           GT  Y  PE I   + + ++   +SLG LLYDM+ G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YKL168C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:131288:133462:-1 gene:YKL168C transcript:YKL168C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KKQ8 description:Putative serine/threonine protein kinase with unknown cellular role; KKQ8 has a paralog, HAL5, that arose from the whole genome duplication [Source:SGD;Acc:S000001651]</Hit_def>
  <Hit_accession>YKL168C</Hit_accession>
  <Hit_len>724</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>1.36316e-10</Hsp_evalue>
      <Hsp_query-from>348</Hsp_query-from>
      <Hsp_query-to>950</Hsp_query-to>
      <Hsp_hit-from>416</Hsp_hit-from>
      <Hsp_hit-to>640</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>227</Hsp_align-len>
      <Hsp_qseq>AVLGSGGFGTVYEGVRL---SDNLPVAIKHVGKD---RVTEWGQLPSGAL------VPLEVVL---MKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESV----ARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDT------VYTDFDGTRVY-SPPEWIRYHRYHGRSAAVWSLGVLLYDMVCG</Hsp_qseq>
      <Hsp_hseq>GLVGAGAYGEVKLCARLRNEKDSPPFETYHDSKYIYYAVKELKPKPDSDLEKFCTKITSEFIIGHSLSHYHKNGKKPAPNILNVFDILEDSSSFIEVMEFCPAG-DLYGMLVGKSKLKGRLHPLEADCFMKQLLHGVKFMHDHGIAHCDLKPENILF-YPHGLLKICDFGTSSVFQTAWERRVHAQKGIIGSEPYVAPEEFVDGEYYDPRLIDCWSCGVVYITMILG</Hsp_hseq>
      <Hsp_midline> ++G+G +G V    RL    D+ P    H  K     V E    P   L      +  E ++   +    + G  P   ++ + D  E + SF+ +ME   A  DL+  +  +  L   +    A  F +Q++  V+  H  G+ H DLK ENIL     G LK+ DFG+ ++ +              G+  Y +P E++    Y  R    WS GV+   M+ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>1.43828e-10</Hsp_evalue>
      <Hsp_query-from>354</Hsp_query-from>
      <Hsp_query-to>1157</Hsp_query-to>
      <Hsp_hit-from>29</Hsp_hit-from>
      <Hsp_hit-to>319</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>120</Hsp_positive>
      <Hsp_gaps>51</Hsp_gaps>
      <Hsp_align-len>305</Hsp_align-len>
      <Hsp_qseq>LGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFE-----HDEEIL-----------------------------RAHVAFRKR---VSPECQELIRACLNVRPSERPLLDEILAHPWLAESESEGEPALPLAKRD</Hsp_qseq>
      <Hsp_hseq>VGMGAFGLVCSATDTLTSQPVAIKKIMK----PFSTAVLAKRTYRELKLLKHLRHEN------LICLQDIFLSPLEDIYFVTELQGT-DLHRLLQTR-PLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILIN-ENCDLKICDFGL-ARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENTLKFVTSLPHRDPIPFSERFKTVEPDAVDLLEKMLVFDPKKRITAADALAHPYSAPYHDPTDEPVADAKFD</Hsp_hseq>
      <Hsp_midline>+G G FG V        + PVAIK + K     +           E+ L+K +          +I L D F      +  +   +   DL   +  R  L +   + F  Q++  +++ H+ GV+HRDLK  NIL++ +  +LK+ DFG  A ++D   T +  TR Y  PE +   + +     +WS G +  +M+ G   F      H   I+                             R  + F +R   V P+  +L+   L   P +R    + LAHP+ A      +  +  AK D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>1.6107e-10</Hsp_evalue>
      <Hsp_query-from>330</Hsp_query-from>
      <Hsp_query-to>1097</Hsp_query-to>
      <Hsp_hit-from>544</Hsp_hit-from>
      <Hsp_hit-to>822</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>122</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>290</Hsp_align-len>
      <Hsp_qseq>KLYRVGAVLGSGGFGTVYEGVRL----SDNLPVAIK------HVGKDRVT----EWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFV-LIMERPEAARDLFDFI-------TERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKD--TVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEEILRAHVAFRKRVSP----------ECQELIRACLNVRPSERPLLDEILAH</Hsp_qseq>
      <Hsp_hseq>QCFKVIEKAGQGASGSVYLAERTHIPTESNMIELINNDIDEPHVG-DKVAIKQMVLSKQPRKELIVNEILVMKD------SRHKNIVNFLEAYLRTDDDLWVVMEFMEGG-SLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDT-RARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEK-IDVWSLGIMTIEMLEGEPPYL-NEDPLKALYLIATNGTPKLKHPESLSLEIKRFLSVCLCVDVRYRASTEELLHH</Hsp_hseq>
      <Hsp_midline>+ ++V    G G  G+VY   R       N+   I       HVG D+V        + P   L+  E+++MK       S    ++  L+ + R D  + ++ME  E    L D I            L E       R+  + ++  H   ++HRD+K +N+L+D  R  +K+ DFG  A L D  +      GT  +  PE ++   Y  +   VWSLG++  +M+ G+ P+  +E+ L+A        +P          E +  +  CL V    R   +E+L H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YKL198C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:68232:70220:-1 gene:YKL198C transcript:YKL198C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK1 description:Putative serine/threonine protein kinase; regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein; PTK1 has a paralog, PTK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001681]</Hit_def>
  <Hit_accession>YKL198C</Hit_accession>
  <Hit_len>662</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>1.67341e-10</Hsp_evalue>
      <Hsp_query-from>615</Hsp_query-from>
      <Hsp_query-to>962</Hsp_query-to>
      <Hsp_hit-from>287</Hsp_hit-from>
      <Hsp_hit-to>423</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>RDLFDFITERGALAESVARGF--FRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTD-------------FDGTRVYSPPEWIRY-----------HRYHGRSAAVWSLGVLLYDMVCGDIPF</Hsp_qseq>
      <Hsp_hseq>RDLFAMIQKSGWRSVALAEKFCIFKQVACGVKFCHDQGIAHRDLKPENVLLS-PDGVCKLTDFG----ISDWYHTDPHDLSSPVKKCAGMIGSPPYAPPEVMFYDSKKHYDTELQQPYDPRALDCYGLGIILMTLVNNVIPF</Hsp_hseq>
      <Hsp_midline>RDLF  I + G  + ++A  F  F+QV   V+ CH  G+ HRDLK EN+L+    G  KL DFG    + D  +TD               G+  Y+PPE + Y             Y  R+   + LG++L  +V   IPF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>4.18019e-10</Hsp_evalue>
      <Hsp_query-from>336</Hsp_query-from>
      <Hsp_query-to>950</Hsp_query-to>
      <Hsp_hit-from>369</Hsp_hit-from>
      <Hsp_hit-to>566</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>208</Hsp_align-len>
      <Hsp_qseq>YRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERG--ALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILV-DLKRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCG</Hsp_qseq>
      <Hsp_hseq>YLVLDILGQGTFGQVVKCQNLLTKEILAVK-VVKSRTEYLTQSITEAKI-LELLNQK----IDPTNKHHFLRMYDSFVHKNHLCLVFEL--LSNNLYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPELKIIDFGSSCEEARTVYT-YIQSRFYRAPEIILGIPY-STSIDMWSLGCIVAELFLG</Hsp_hseq>
      <Hsp_midline>Y V  +LG G FG V +   L     +A+K V K R     Q  + A + LE++  K       +     +R+ D F   +   L+ E    + +L++ + +     L+  + R F  Q+++++       ++H DLK ENIL+    + ELK+IDFGS      TVYT +  +R Y  PE I    Y   S  +WSLG ++ ++  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>71</Hit_num>
  <Hit_id>YBR059C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:356861:360187:-1 gene:YBR059C transcript:YBR059C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AKL1 description:Ser-Thr protein kinase; member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization [Source:SGD;Acc:S000000263]</Hit_def>
  <Hit_accession>YBR059C</Hit_accession>
  <Hit_len>1108</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>5.01048e-10</Hsp_evalue>
      <Hsp_query-from>489</Hsp_query-from>
      <Hsp_query-to>1097</Hsp_query-to>
      <Hsp_hit-from>94</Hsp_hit-from>
      <Hsp_hit-to>316</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>236</Hsp_align-len>
      <Hsp_qseq>EVVLMKKVLQAGASPCAGVIRLLDWFERADS----------FVLIMER-PEAARDLFDFITER--GALAESVARGFFRQVVEAVRHCH--ACGVLHRDLKDENILVDLKRGELKLIDFGSG-------------ALLKDTVYTDFDGTRVYSPPEWIRYHRYH--GRSAAVWSLGVLLYDMVCGDIPFEHDEEILRAHVAFR---KRVSPECQELIRACLNVRPSERPLLDEILAH</Hsp_qseq>
      <Hsp_hseq>EVEVMKKL--------KGAPNIVQYFDSNASRRRDGVQGFEVLLLMELCPN--KSLLDYMNQRLSTKLTEAEIVKIMYDVALSISQMHYLPVSLIHRDIKIENVLVDAKNN-FKLADFGSTSTCFPIVTTHQDIALLTQNIY--VHTTPQYRSPEMIDLYRCLPINEKSDIWALGVFLYKLLFFTTPFEMTGQFAILHSKYEFPVNKYSSKLINLIIIMLAENPNLRPNIYQVLYH</Hsp_hseq>
      <Hsp_midline>EV +MKK+         G   ++ +F+   S           +L+ME  P   + L D++ +R    L E+        V  ++   H     ++HRD+K EN+LVD K    KL DFGS              ALL   +Y     T  Y  PE I  +R       + +W+LGV LY ++    PFE   +    H  +     + S +   LI   L   P+ RP + ++L H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>72</Hit_num>
  <Hit_id>YOR267C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:822588:824867:-1 gene:YOR267C transcript:YOR267C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRK1 description:Protein kinase; implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005793]</Hit_def>
  <Hit_accession>YOR267C</Hit_accession>
  <Hit_len>759</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>5.81652e-10</Hsp_evalue>
      <Hsp_query-from>327</Hsp_query-from>
      <Hsp_query-to>965</Hsp_query-to>
      <Hsp_hit-from>212</Hsp_hit-from>
      <Hsp_hit-to>422</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>229</Hsp_align-len>
      <Hsp_qseq>EKLYRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAG-------VIRLLDWFE--RADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKD------TVYTDFDGTRVYSPPEWIRYHR-YHGRSAAVWSLGVLLYDMVCGDIPFE</Hsp_qseq>
      <Hsp_hseq>QKYGKLGKLLGSGAGGSVKVLVRPTDGATFAVKEFRPRKPNE--------------SVKEYAKKCTAEFCIGSTLHHPNVIETVDVFSDSKQNKYYEVMEY--CPIDFFAVVMT-GKMSRGEINCCLKQLTEGVKYLHSMGLAHRDLKLDNCVM-TSQGILKLIDFGSAVVFRYPFEDGVTMAHGIVGSDPYLAPEVITSTKSYDPQCVDIWSIGIIYCCMVLKRFPWK</Hsp_hseq>
      <Hsp_midline>+K  ++G +LGSG  G+V   VR +D    A+K     +  E               + +   +  A  C G       VI  +D F   + + +  +ME      D F  +   G ++        +Q+ E V++ H+ G+ HRDLK +N ++   +G LKLIDFGS  + +       T+     G+  Y  PE I   + Y  +   +WS+G++   MV    P++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>73</Hit_num>
  <Hit_id>YDL079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:312951:314748:-1 gene:YDL079C transcript:YDL079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRK1 description:Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication [Source:SGD;Acc:S000002237]</Hit_def>
  <Hit_accession>YDL079C</Hit_accession>
  <Hit_len>501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>5.99562e-10</Hsp_evalue>
      <Hsp_query-from>336</Hsp_query-from>
      <Hsp_query-to>950</Hsp_query-to>
      <Hsp_hit-from>164</Hsp_hit-from>
      <Hsp_hit-to>361</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>209</Hsp_align-len>
      <Hsp_qseq>YRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALV--PLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACG-VLHRDLKDENILVDLKRGELKLIDFGSGALLK-DTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCG</Hsp_qseq>
      <Hsp_hseq>YPTTEVVGHGSFGVVVTTVIIETNQKVAIKKVLQDRRYKNRELETMKMLCHPNTVGLQYYFYEKDEEDEVYLNLVLDYMPQS-----LYQR------LRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLG</Hsp_hseq>
      <Hsp_midline>Y    V+G G FG V   V +  N  VAIK V +DR  +  +L +  ++  P  V L     +        +  +LD+  ++     + +R      L  F+  +  +     + +  Q+ +A+ + H    + HRD+K +N+LVD      K+ DFGS   LK D     +  +R Y  PE +     +     VWS   ++ +++ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>74</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>9.08349e-10</Hsp_evalue>
      <Hsp_query-from>324</Hsp_query-from>
      <Hsp_query-to>1004</Hsp_query-to>
      <Hsp_hit-from>56</Hsp_hit-from>
      <Hsp_hit-to>297</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>259</Hsp_align-len>
      <Hsp_qseq>LEKLYRVGAVLGSGGFGTVYEGVRLSDNLPVAIKH----VGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDW-FERA------------DSFVLIMERPEAARDLFDFI-TERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFG--------------SGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEEILRAHVAFR</Hsp_qseq>
      <Hsp_hseq>FQNHYREDEKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQR--------EITILKRLNHKN------IIKLIEMVYDHSPDITNAASSNLHKSFYMIL--PYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILID-HNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFK</Hsp_hseq>
      <Hsp_midline> +  YR    LG G FG VY+G+ L     VA+K     V KD      Q         E+ ++K++          +I+L++  ++ +             SF +I+  P    DL   +   R  L     +    Q++E + + H    +HRD+K  NIL+D   G LKL DFG               G       YT    TR Y  PE +   + +  +  +W +G +  +        +   +I + HV F+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>75</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>1.76158e-09</Hsp_evalue>
      <Hsp_query-from>351</Hsp_query-from>
      <Hsp_query-to>800</Hsp_query-to>
      <Hsp_hit-from>357</Hsp_hit-from>
      <Hsp_hit-to>495</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>150</Hsp_align-len>
      <Hsp_qseq>VLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFG</Hsp_qseq>
      <Hsp_hseq>VIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQL-------AHVKAERDVLAGSDSPW--VVSLYYSFQDAQYLYLIMEFLPGG-DLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDI-RGHIKLSDFG</Hsp_hseq>
      <Hsp_midline>V+G G FG V    +       A+K + K  + +  QL         V   + VL    SP   V+ L   F+ A    LIME      DL   +       E V R +  + + A+   H  G +HRD+K +NIL+D+ RG +KL DFG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>76</Hit_num>
  <Hit_id>YIL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:183937:186369:1 gene:YIL095W transcript:YIL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRK1 description:Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton and reduces endocytic ability of cell through the phosphorylation of the Pan1p-Sla1p-End3p protein complex; PRK1 has a paralog, ARK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001357]</Hit_def>
  <Hit_accession>YIL095W</Hit_accession>
  <Hit_len>810</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>2.09847e-09</Hsp_evalue>
      <Hsp_query-from>621</Hsp_query-from>
      <Hsp_query-to>1091</Hsp_query-to>
      <Hsp_hit-from>116</Hsp_hit-from>
      <Hsp_hit-to>292</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>178</Hsp_align-len>
      <Hsp_qseq>LFDFITER--GALAESVARGFFRQVVEAVRHCHACG--VLHRDLKDENILVDLKRGELKLIDFGS--GALLKDTVYTDFD---------GTRVYSPPEWIRYHR--YHGRSAAVWSLGVLLYDMVCGDIPFEHDEE--ILRAHVAFRK--RVSPECQELIRACLNVRPSERPLLDEIL</Hsp_qseq>
      <Hsp_hseq>LIDFMNTRLQNRLQESEILEIMSQTVQGITAMHALQPPLIHRDIKIENVLIS-HDGLYKVCDFGSVSGVIRPPRNTQEFNYVQHDILTNTTAQYRSPEMIDLYRGLPIDEKSDIWALGVFLYKICYYTTPFEKSGEAGILHARYQYPSFPQYSDRLKNLIRLMLMEAPSQRPNICQVL</Hsp_hseq>
      <Hsp_midline>L DF+  R    L ES       Q V+ +   HA    ++HRD+K EN+L+    G  K+ DFGS  G +       +F+          T  Y  PE I  +R       + +W+LGV LY +     PFE   E  IL A   +    + S   + LIR  L   PS+RP + ++L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>77</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>3.63898e-09</Hsp_evalue>
      <Hsp_query-from>306</Hsp_query-from>
      <Hsp_query-to>932</Hsp_query-to>
      <Hsp_hit-from>28</Hsp_hit-from>
      <Hsp_hit-to>240</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>234</Hsp_align-len>
      <Hsp_qseq>SRERESLEKLYRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFV------LIMERPE----AARDLFDF-----ITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVY----------TDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLL</Hsp_qseq>
      <Hsp_hseq>AKERISIPGYYEIIQFLGKGAYGTV-----------CSVKFKGRSPAARIAVKKISNIFNKEILLKRAIRE---------LKFMNFFKGHKNIVNLIDLEIVTSSPYDGLYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTL-NGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCIL</Hsp_hseq>
      <Hsp_midline>++ER S+   Y +   LG G +GTV            ++K  G+             +   E++L + + +         ++ +++F+   + V      ++   P       ++L D+     I     L+E   + F  Q++  +++ H+  V+HRDLK  NIL  L  G LK+ DFG    +    +          T++  TR Y  PE +  ++ + +S  +W++G +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>78</Hit_num>
  <Hit_id>YNL183C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:293137:295509:-1 gene:YNL183C transcript:YNL183C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NPR1 description:Protein kinase; stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p; negatively regulates Ldb19p-mediated endocytosis through phosphorylation of Ldb19p, which prevents its association with the plasma membrane; Npr1p activity is negatively regulated via phosphorylation by the TOR complex; NPR1 has a paralog, PRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005127]</Hit_def>
  <Hit_accession>YNL183C</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>5.17247e-09</Hsp_evalue>
      <Hsp_query-from>540</Hsp_query-from>
      <Hsp_query-to>965</Hsp_query-to>
      <Hsp_hit-from>499</Hsp_hit-from>
      <Hsp_hit-to>642</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>148</Hsp_align-len>
      <Hsp_qseq>GVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALL-----KDTV-YTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFE</Hsp_qseq>
      <Hsp_hseq>NIIETIEIVYENDRILQVMEYCE--YDLFAIVMSNKMSYEEIC-CCFKQILTGVQYLHSIGLAHRDLKLDNCVIN-EKGIVKLIDFGAAVVFSYPFSKNLVEASGIVGSDPYLAPEVCIFAKYDPRPVDIWSSAIIFACMILKKFPWK</Hsp_hseq>
      <Hsp_midline> +I  ++     D  + +ME  E   DLF  +       E +    F+Q++  V++ H+ G+ HRDLK +N +++ ++G +KLIDFG+  +      K+ V  +   G+  Y  PE   + +Y  R   +WS  ++   M+    P++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>79</Hit_num>
  <Hit_id>YDR247W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:956013:957398:1 gene:YDR247W transcript:YDR247W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VHS1 description:Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; VHS1 has a paralog, SKS1, that arose from the whole genome duplication [Source:SGD;Acc:S000002655]</Hit_def>
  <Hit_accession>YDR247W</Hit_accession>
  <Hit_len>461</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>1.18791e-08</Hsp_evalue>
      <Hsp_query-from>489</Hsp_query-from>
      <Hsp_query-to>1091</Hsp_query-to>
      <Hsp_hit-from>120</Hsp_hit-from>
      <Hsp_hit-to>327</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>57</Hsp_gaps>
      <Hsp_align-len>233</Hsp_align-len>
      <Hsp_qseq>EVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFG---SGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAA---------------VWSLGVLLYDMVCGDIP--------------FEHDEEILRAHVAFRKRVSPECQELIRACLNVRPSERPLLDEIL</Hsp_qseq>
      <Hsp_hseq>NIVTIHEVLQSAV--CTFIV--MDYYP-TDLFTSIVDNRH-------FVT-NGLLVKKV----FLQICSALNYCHEHGIYHCDIKPENLLLDTEDNVF-LCDFGLSTTSTYIKPNVCI---GSSYYMPPERISFDGRVSSSKSGGHKLGKVCPSCNGDLWSLGIILINLTCIRNPWLKADKTEDNTYYYFTKDPNILKQILP----LSDDFYSLLSKILQVNPKNRMSLQELM</Hsp_hseq>
      <Hsp_midline> +V + +VLQ+    C  ++  +D++   D F  I++          F+T  G L + V    F Q+  A+ +CH  G+ H D+K EN+L+D +     L DFG   +   +K  V     G+  Y PPE I +      S +               +WSLG++L ++ C   P              F  D  IL+  +     +S +   L+   L V P  R  L E++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>80</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>1.3643e-08</Hsp_evalue>
      <Hsp_query-from>618</Hsp_query-from>
      <Hsp_query-to>1109</Hsp_query-to>
      <Hsp_hit-from>114</Hsp_hit-from>
      <Hsp_hit-to>319</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>207</Hsp_align-len>
      <Hsp_qseq>DLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFG------SGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHD-----------------EEILR--------------------AHVAFRKRVSPECQELIRACLNVRPSERPLLDEILAHPWLA</Hsp_qseq>
      <Hsp_hseq>DMHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNAD-CQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPYLS</Hsp_hseq>
      <Hsp_midline>D+   I     L ++  + F  Q++  +++ H+  VLHRDLK  N+LV+    +LK+ DFG         +      T++  TR Y  PE +  ++ + ++  VWS G +L + + G   F+                   +E LR                      V      + +  +L+   L   P +R  +DE L HP+L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>81</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>1.45257e-08</Hsp_evalue>
      <Hsp_query-from>588</Hsp_query-from>
      <Hsp_query-to>965</Hsp_query-to>
      <Hsp_hit-from>305</Hsp_hit-from>
      <Hsp_hit-to>446</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>LIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDL---------------KRGELKLIDFG-SGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFE</Hsp_qseq>
      <Hsp_hseq>MIMSYCPAGDLLAAVMARNGRLEAWLIQRIFTEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLCKKIENNEMCTARCGSEDYVSPEILMGVPYDGHLSDTWALGVILYSLFEDRLPFD</Hsp_hseq>
      <Hsp_midline>+IM    A   L   +   G L   + +  F +VV AV++ H   ++HRDLK ENIL+                 K+  ++L DFG    +  + + T   G+  Y  PE +    Y G  +  W+LGV+LY +    +PF+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>82</Hit_num>
  <Hit_id>YJR059W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:545787:548243:1 gene:YJR059W transcript:YJR059W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK2 description:Serine/threonine protein kinase; involved in regulation of ion transport across plasma membrane; carboxyl terminus is essential for glucose-dependent Pma1p activation via phosphorylation of Pma1p-Ser899; enhances spermine uptake; PTK2 has a paralog, PTK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003820]</Hit_def>
  <Hit_accession>YJR059W</Hit_accession>
  <Hit_len>818</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>1.98224e-08</Hsp_evalue>
      <Hsp_query-from>588</Hsp_query-from>
      <Hsp_query-to>962</Hsp_query-to>
      <Hsp_hit-from>339</Hsp_hit-from>
      <Hsp_hit-to>482</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>148</Hsp_align-len>
      <Hsp_qseq>LIMERPEAARDLFDFITERGALAESVARGF--FRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTDFD----------GTRVYSPPEWIRYHR-----------YHGRSAAVWSLGVLLYDMVCGDIPF</Hsp_qseq>
      <Hsp_hseq>FIMEL--GVKDLFQLMERTGWKNVPFNEKYCLFKQVAQGIKFCHDNGIAHRDLKPENVLIS-KEGICKLTDFGISDWYH-VIPHDYTSPVKTCQGMIGSPPYTPPEVMYFDAKKHYPEKFQKPYNPLAMDSYALGIMLITMINNIIPF</Hsp_hseq>
      <Hsp_midline> IME     +DLF  +   G         +  F+QV + ++ CH  G+ HRDLK EN+L+  K G  KL DFG        +  D+           G+  Y+PPE + +             Y+  +   ++LG++L  M+   IPF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>83</Hit_num>
  <Hit_id>YFL033C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:69115:74427:-1 gene:YFL033C transcript:YFL033C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM15 description:Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase [Source:SGD;Acc:S000001861]</Hit_def>
  <Hit_accession>YFL033C</Hit_accession>
  <Hit_len>1770</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>2.27934e-08</Hsp_evalue>
      <Hsp_query-from>330</Hsp_query-from>
      <Hsp_query-to>800</Hsp_query-to>
      <Hsp_hit-from>792</Hsp_hit-from>
      <Hsp_hit-to>938</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>157</Hsp_align-len>
      <Hsp_qseq>KLYRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFG</Hsp_qseq>
      <Hsp_hseq>KDYDILKPISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQVTN--------VKSERAIMMVQSDKPYVARLFASFQNKDNLFLVMEYLPGG-DLATLIKMMGYLPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLID-NAGHVKLTDFG</Hsp_hseq>
      <Hsp_midline>K Y +   +  G +G+VY   +       AIK + K  +    Q+ +        V  ++ +    S    V RL   F+  D+  L+ME      DL   I   G L +  A+ +  ++V  V   H  G++H DLK EN+L+D   G +KL DFG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>84</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>4.08292e-08</Hsp_evalue>
      <Hsp_query-from>675</Hsp_query-from>
      <Hsp_query-to>1106</Hsp_query-to>
      <Hsp_hit-from>815</Hsp_hit-from>
      <Hsp_hit-to>981</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>175</Hsp_align-len>
      <Hsp_qseq>FFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTDFD--------------------GTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEE---ILRAHVAFRKRVSPEC--------QELIRACLNVRPSERPLLDEILAHPWL</Hsp_qseq>
      <Hsp_hseq>LFRQILEALSYIHSQGIIHRDLKPMNIFIDESR-NVKIGDFG----LAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVLDGTGHYNEKIDMYSLGIIFFEMI---YPFSTGMERVNILKKLRSVSIEFPPDFDDNKMKVEKKIIRLLIDHDPNKRPGARTLLNSGWL</Hsp_hseq>
      <Hsp_midline> FRQ++EA+ + H+ G++HRDLK  NI +D  R  +K+ DFG    L   V+   D                    GT +Y   E +    ++     ++SLG++ ++M+    PF    E   IL+   +      P+         +++IR  ++  P++RP    +L   WL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>85</Hit_num>
  <Hit_id>YPL026C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:500675:502183:-1 gene:YPL026C transcript:YPL026C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKS1 description:Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway; SKS1 has a paralog, VHS1, that arose from the whole genome duplication [Source:SGD;Acc:S000005947]</Hit_def>
  <Hit_accession>YPL026C</Hit_accession>
  <Hit_len>502</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>4.42731e-08</Hsp_evalue>
      <Hsp_query-from>336</Hsp_query-from>
      <Hsp_query-to>992</Hsp_query-to>
      <Hsp_hit-from>10</Hsp_hit-from>
      <Hsp_hit-to>279</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>69</Hsp_gaps>
      <Hsp_align-len>279</Hsp_align-len>
      <Hsp_qseq>YRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHV----------GKDRVTEWGQLPSGALVPLEV---------------VLMKKVLQAGASPC------------------AGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAES--VARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRY------HRYH---------GRSAAVWSLGVLLYDMVCGDIPFEHDEEILRAH</Hsp_qseq>
      <Hsp_hseq>FRITAQIGSGAYGLVFHVVDILTSREYAVKTVFKSSSMDEFYNKNGLNNNSQVARTTLLQTQLYHFFKSFQKKLFLPSVDLDSILQLTENELNRLPHYREIAFQLRVQSHGNIVKIHQVLESSIATFIVMDYYD--RDLFTSIVDDKHFVNHGILIKKVFLQLCSALDHCHRLGIYHCDIKPENVLLD-RNDNAYLCDFGLSTKSKYLAPNVCVGSSYYMAPERILYCLNTTTNGIHVDECCSSLPTDTGDIWSLGIILINLTCIRNPW------LKAH</Hsp_hseq>
      <Hsp_midline>+R+ A +GSG +G V+  V +  +   A+K V           K+ +    Q+    L+  ++               V +  +LQ   +                      ++++    E + +  ++M+  +  RDLF  I +         + +  F Q+  A+ HCH  G+ H D+K EN+L+D +     L DFG     K        G+  Y  PE I Y      +  H           +  +WSLG++L ++ C   P+      L+AH</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>86</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>6.89949e-08</Hsp_evalue>
      <Hsp_query-from>666</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>166</Hsp_hit-from>
      <Hsp_hit-to>279</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>115</Hsp_align-len>
      <Hsp_qseq>ARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFG---SGALLKDTVYTDFD--------GTRVYSPPEWIRYHRYHGRSAA--VWSLGVLLYDMVCGDIPFEHD</Hsp_qseq>
      <Hsp_hseq>SRKVVLDVVSGLEYLHSQGITHRDIKPSNLLIS-SNGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPFNAN</Hsp_hseq>
      <Hsp_midline>+R     VV  + + H+ G+ HRD+K  N+L+    G +K+ DFG   S A     + +  +        GT  +  PE     + +  S+A  +WSLGV +Y ++ G +PF  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>87</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>1.43678e-07</Hsp_evalue>
      <Hsp_query-from>354</Hsp_query-from>
      <Hsp_query-to>962</Hsp_query-to>
      <Hsp_hit-from>183</Hsp_hit-from>
      <Hsp_hit-to>415</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>52</Hsp_gaps>
      <Hsp_align-len>244</Hsp_align-len>
      <Hsp_qseq>LGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGA----------------LLKDTVYTDF------DGTRVYS---------------PPEWIRYHRYHGR----SAAVWSLGVLLYDMVCGDIPF</Hsp_qseq>
      <Hsp_hseq>VGQGGYGQVYLARKKDTKEVCALKILNKKLLFKLNETK-------HVLTERDILTTTRSEW--LVKLLYAFQDLQSLYLAMEFVPGG-DFRTLLINTRCLKSGHARFYISEMFCAVNALHDLGYTHRDLKPENFLIDAK-GHIKLTDFGLAAGTISNERIESMKIRLEKIKDLEFPAFTEKSIEDRRKMYNQLREKEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPF</Hsp_hseq>
      <Hsp_midline>+G GG+G VY   +       A+K + K  + +  +          V+  + +L    S    +++LL  F+   S  L ME      D    +     L    AR +  ++  AV   H  G  HRDLK EN L+D K G +KL DFG  A                 +KD  +  F      D  ++Y+                P+++      G+    +   WSLG +L++ + G  PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>88</Hit_num>
  <Hit_id>YPR111W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:747306:749000:1 gene:YPR111W transcript:YPR111W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF20 description:Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006315]</Hit_def>
  <Hit_accession>YPR111W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>1.4375e-07</Hsp_evalue>
      <Hsp_query-from>330</Hsp_query-from>
      <Hsp_query-to>809</Hsp_query-to>
      <Hsp_hit-from>167</Hsp_hit-from>
      <Hsp_hit-to>315</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>KLYRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGA</Hsp_qseq>
      <Hsp_hseq>KDFQILTQVGQGGYGQVYLAKKKDSDEICALKILNKKLLFKLNETN-------HVLTERDILTTTRSDW--LVKLLYAFQDPESLYLAMEFVPGG-DFRTLLINTRILKSGHARFYISEMFCAVNALHELGYTHRDLKPENFLIDAT-GHIKLTDFGLAA</Hsp_hseq>
      <Hsp_midline>K +++   +G GG+G VY   +   +   A+K + K  + +  +          V+  + +L    S    +++LL  F+  +S  L ME      D    +     L    AR +  ++  AV   H  G  HRDLK EN L+D   G +KL DFG  A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>89</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>1.96146e-07</Hsp_evalue>
      <Hsp_query-from>324</Hsp_query-from>
      <Hsp_query-to>950</Hsp_query-to>
      <Hsp_hit-from>441</Hsp_hit-from>
      <Hsp_hit-to>649</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>220</Hsp_align-len>
      <Hsp_qseq>LEKLYRVGAVLGSGGFGTVYEGVRLSDNLPVAIKHVGKDRVTEWGQLPSGALVPLEVVLMKKVLQAGASPCAGVIRLLDWFER---ADSFVLIMERPEAARDLFDFITERGALAESVARGF--FRQVVE---AVRHCH-ACGVLHRDLKDENILVDLKRGELKLIDFGSGAL--LKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCG</Hsp_qseq>
      <Hsp_hseq>FEKFTNVHSI-GKGQFSTVYQVTFAQTNKKYAIKAIKPNKYNSLKR------ILLEIKILNEVTNQITMDQEGKEYIIDYISSWKFQNSYYIMTELCENG-NLDGFLQEQVIAKKKRLEDWRIWKIIVELSLALRFIHDSCHIVHLDLKPANVMITFE-GNLKLGDFGMATHLPLEDKSFEN-EGDREYIAPEIISDCTYDYK-ADIFSLGLMIVEIAAN</Hsp_hseq>
      <Hsp_midline> EK   V ++ G G F TVY+      N   AIK +  ++     +      + LE+ ++ +V         G   ++D+       +S+ ++ E  E   +L  F+ E+    +     +  ++ +VE   A+R  H +C ++H DLK  N+++  + G LKL DFG      L+D  + + +G R Y  PE I    Y  + A ++SLG+++ ++   </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>90</Hit_num>
  <Hit_id>YNL020C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:595623:597539:-1 gene:YNL020C transcript:YNL020C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ARK1 description:Serine/threonine protein kinase; involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis; ARK1 has a paralog, PRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004965]</Hit_def>
  <Hit_accession>YNL020C</Hit_accession>
  <Hit_len>638</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>2.12363e-07</Hsp_evalue>
      <Hsp_query-from>621</Hsp_query-from>
      <Hsp_query-to>1091</Hsp_query-to>
      <Hsp_hit-from>117</Hsp_hit-from>
      <Hsp_hit-to>293</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>178</Hsp_align-len>
      <Hsp_qseq>LFDFITER--GALAESVARGFFRQVVEAVRHCHACG--VLHRDLKDENILVDLKRGELKLIDFGSGALL-------KDTVYTDFD----GTRVYSPPEWIRYHR--YHGRSAAVWSLGVLLYDMVCGDIPFEH--DEEILRAHVAF--RKRVSPECQELIRACLNVRPSERPLLDEIL</Hsp_qseq>
      <Hsp_hseq>LIDFMNTRLQNRLHEFEILQIMSQVTQGVAAMHALQPPLIHRDIKIENVLIS-ANNEYKLCDFGSVCGIIRPPRNSQELSYVQQDILKNTTAQYRSPEMIDTFRGLPIDEKSDIWALGIFLYKLCYYTTPFEKGGDLAILSGKFEFPLYPNYSEQLKGLIRDILVQDPRHRPNVYQLL</Hsp_hseq>
      <Hsp_midline>L DF+  R    L E        QV + V   HA    ++HRD+K EN+L+     E KL DFGS   +       ++  Y   D     T  Y  PE I   R       + +W+LG+ LY +     PFE   D  IL     F      S + + LIR  L   P  RP + ++L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>91</Hit_num>
  <Hit_id>YKL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:347214:349136:-1 gene:YKL048C transcript:YKL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ELM1 description:Serine/threonine protein kinase; regulates the orientation checkpoint, the morphogenesis checkpoint and the metabolic switch from fermentative to oxidative metabolism by phosphorylating the activation loop of Kin4p, Hsl1p and Snf4p respectively; cooperates with Hsl7p in recruiting Hsl1p to the septin ring, a prerequisite for subsequent recruitment, phosphorylation, and degradation of Swe1p; forms part of the bud neck ring; regulates cytokinesis [Source:SGD;Acc:S000001531]</Hit_def>
  <Hit_accession>YKL048C</Hit_accession>
  <Hit_len>640</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>7.22625e-07</Hsp_evalue>
      <Hsp_query-from>660</Hsp_query-from>
      <Hsp_query-to>992</Hsp_query-to>
      <Hsp_hit-from>234</Hsp_hit-from>
      <Hsp_hit-to>364</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>131</Hsp_align-len>
      <Hsp_qseq>SVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTV-YTDFD-------------GTRVYSPPEWI------RYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEEILRAH</Hsp_qseq>
      <Hsp_hseq>TFAKKILEDMTKGLEYLHSQGCIHRDIKPSNILLDEEEKVAKLSDFGSCIFTPQSLPFSDANFEDCFQRELNKIVGTPAFIAPELCHLGNSKRDFVTDGFKLDIWSLGVTLYCLLYNELPFFGENEFETYH</Hsp_hseq>
      <Hsp_midline>+ A+     + + + + H+ G +HRD+K  NIL+D +    KL DFGS      ++ ++D +             GT  +  PE        R     G    +WSLGV LY ++  ++PF  + E    H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>92</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>7.2423e-07</Hsp_evalue>
      <Hsp_query-from>540</Hsp_query-from>
      <Hsp_query-to>962</Hsp_query-to>
      <Hsp_hit-from>146</Hsp_hit-from>
      <Hsp_hit-to>289</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>153</Hsp_align-len>
      <Hsp_qseq>GVIRLLDWFERADSFVLIMERPEAARDLFDFITERGALAESVA-RGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTDFD---GTRVYSPPEWI--------RYHRYHGRSAAVWSLGVLLYDMVCGDIPF</Hsp_qseq>
      <Hsp_hseq>NIAALLDFF---DSYI-IMEYCSGG-DLYEAIKADAVPKKTKSITHIITQIMDAIEYVHNKGIYHRDIKPENILISGIDWTIKLTDWG----LATTDKTSMDRNVGSERYMSPELFDSNLDIKERKEPYDCAKVDLWAMGIVFLNIVFHKNPF</Hsp_hseq>
      <Hsp_midline> +  LLD+F   DS++ IME      DL++ I       ++ +      Q+++A+ + H  G+ HRD+K ENIL+      +KL D+G    L  T  T  D   G+  Y  PE          R   Y      +W++G++  ++V    PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>93</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>4.64134e-06</Hsp_evalue>
      <Hsp_query-from>609</Hsp_query-from>
      <Hsp_query-to>1040</Hsp_query-to>
      <Hsp_hit-from>239</Hsp_hit-from>
      <Hsp_hit-to>387</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>154</Hsp_align-len>
      <Hsp_qseq>AARDLFDFI-----TERGALAESVARGFFRQVVEAVRHCHACGVLHRDLKDENILVDLKRGELKLIDFGSGALLKDTVYTDFDGTRV-----YSPPEWIRYHRYHGRSAAVWSLGVLLYDMVCGDIPFEHDEEILRAHVAFRKRVSPECQELIR</Hsp_qseq>
      <Hsp_hseq>AEHDLLQIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTID-GCVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELI-GLQPIFKGEE---AKLDSKKTVPFQVNQLQR</Hsp_hseq>
      <Hsp_midline>A  DL   I      E+  +   + R    Q+++ V + H   VLHRDLK  NI+V +  G +K+ D G      + + T + G +V     Y  PE +   R++  +  +WS+G +  +++ G  P    EE   A +  +K V  +  +L R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>1930609618</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054859-RA transcript Note:&quot;Similar to DHTKD1 Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial (Pongo abelii)&quot; offset:0 AED:0.28 eAED:0.28 QI:0|0|0|0.84|1|1|13|0|755</Iteration_query-def>
  <Iteration_query-len>2268</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YIL125W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:122689:125733:1 gene:YIL125W transcript:YIL125W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KGD1 description:Subunit of the mitochondrial alpha-ketoglutarate dehydrogenase complex; catalyzes a key step in the tricarboxylic acid (TCA) cycle, the oxidative decarboxylation of alpha-ketoglutarate to form succinyl-CoA [Source:SGD;Acc:S000001387]</Hit_def>
  <Hit_accession>YIL125W</Hit_accession>
  <Hit_len>1014</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>296.975</Hsp_bit-score>
      <Hsp_score>759</Hsp_score>
      <Hsp_evalue>5.64417e-88</Hsp_evalue>
      <Hsp_query-from>247</Hsp_query-from>
      <Hsp_query-to>1929</Hsp_query-to>
      <Hsp_hit-from>128</Hsp_hit-from>
      <Hsp_hit-to>718</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>205</Hsp_identity>
      <Hsp_positive>305</Hsp_positive>
      <Hsp_gaps>100</Hsp_gaps>
      <Hsp_align-len>626</Hsp_align-len>
      <Hsp_qseq>LVSAFREHGHLAARLDPLA---GGEHGPPLRVPPQLLASAYG-----------LQPGV---YRVDGLLAMDKAEATLDEVLRFLQDSYCGAIAVETAQLASAEEREWLAER-------------------------AFDNFVATKFATVKRYGGEGAEAMLPFFHETFRHAALSGLSDLVLAMPHRGRXXXXXXXXXXPPE--FPE----GTRGAV---GDVLSHLTATLDVEAAPGRSVRVALLPNPSHLEAVNPVAVGKARGRQRTRREGHYSGEPGARPGDRVACLQVHGDAAFAGQGIVAETFTLAYLPHYDVGGSVHLIVNNQLGFTTPCEWGRSSLYSSDMGKVVGCAVVHVNGDEVEEVVRAARLAMDYRHRFRRDVIVDLLCYRQWGHNELDDPTVTNPAMYGLIRSRKSVPDSYAERLVSEGVLTEADVELVKSSRFAELXXXXXXXXXXXXXXXXXXXXXXXXXXHYWPGDGAGEPRGRWAGLRRPEARVSRW----DTGAPAELLRFVGA------KSVEVAPD----VAMHGHLFKTHAQLDWATAEALAFGSLLTQGFDVRLSGQDVGRGTFSQRHVMIVCQSSSEAYIPLNHMVPQQEAFLEAAVSSLSEMG</Hsp_qseq>
      <Hsp_hseq>LCRAYQVRGHLKAHIDPLGISFGSNKNNP--VPPELTLDYYGFSKHDLDKEINLGPGILPRFARDG-----KSKMSLKEIVDHLEKLYCSSYGVQYTHIPSKQKCDWLRERIEIPEPYQYTVDQKRQILDRLTWATSFESFLSTKFPNDKRFGLEGLESVVPGIKTLVDRSVELGVEDIVLGMAHRGRLNVLSNVVRKPNESIFSEFKGSSARDDIEGSGDVKYHLGMNYQRPTTSGKYVNLSLVANPSHLESQDPVVLGRTRALLHAKND--------LKEKTKALGVLLHGDAAFAGQGVVYETMGFLTLPEYSTGGTIHVITNNQIGFTTDPRFARSTPYPSDLAKAIDAPIFHVNANDVEAVTFIFNLAAEWRHKFHTDAIIDVVGWRKHGHNETDQPSFTQPLMYKKIAKQKSVIDVYTEKLISEGTFSKKDIDEHKKWVW------------------NLFEDAFEKAKDYVPSQREW-LTAAWEGFKSPKELATEILPHEPTNVPESTLKELGKVLSSWPEGFEVHKNLKRILKNRGKSIETGEGIDWATGEALAFGTLVLDGQNVRVSGEDVERGTFSQRHAVLHDQQSEAIYTPLSTLNNEKADFT-IANSSLSEYG</Hsp_hseq>
      <Hsp_midline>L  A++  GHL A +DPL    G     P  VPP+L    YG           L PG+   +  DG     K++ +L E++  L+  YC +  V+   + S ++ +WL ER                         +F++F++TKF   KR+G EG E+++P        +   G+ D+VL M HRGRLN+L+ +++ P E  F E      R  +   GDV  HL          G+ V ++L+ NPSHLE+ +PV +G+ R     + +         +   +   + +HGDAAFAGQG+V ET     LP Y  GG++H+I NNQ+GFTT   + RS+ Y SD+ K +   + HVN ++VE V     LA ++RH+F  D I+D++ +R+ GHNE D P+ T P MY  I  +KSV D Y E+L+SEG  ++ D++  K   +                           A  Y P          W G + P+   +       T  P   L+ +G       +  EV  +    +   G   +T   +DWAT EALAFG+L+  G +VR+SG+DV RGTFSQRH ++  Q S   Y PL+ +  ++  F   A SSLSE G</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>1.15086e-12</Hsp_evalue>
      <Hsp_query-from>1903</Hsp_query-from>
      <Hsp_query-to>2229</Hsp_query-to>
      <Hsp_hit-from>859</Hsp_hit-from>
      <Hsp_hit-to>969</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>114</Hsp_align-len>
      <Hsp_qseq>AVSSLSEMGPGTSFEPVI-----GDPSANPKEVSRVVLCSGKHYYALHKQXXXXXXXXXXXXXXXXXEICPFPTHALRQQLQRFPNATEFVWAQEEPQNMGCWTFIAPRFRKQL</Hsp_qseq>
      <Hsp_hseq>ARSSLSEFTEG-GFQWIIEDIEHGKSIGTKEETKRLVLLSGQVYTALHKRRESLGDKTTAFLKIE--QLHPFPFAQLRDSLNSYPNLEEIVWCQEEPLNMGSWAYTEPRLHTTL</Hsp_hseq>
      <Hsp_midline>A SSLSE   G  F+ +I     G      +E  R+VL SG+ Y ALHK+RE+LG        +   ++ PFP   LR  L  +PN  E VW QEEP NMG W +  PR    L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1498478353</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054862-RA transcript Note:&quot;Similar to ERC1 ELKS/Rab6-interacting/CAST family member 1 (Homo sapiens)&quot; offset:0 AED:0.77 eAED:0.77 QI:0|0|0|0.12|1|1|8|0|315</Iteration_query-def>
  <Iteration_query-len>948</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>524335142</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

