<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0056809-RA transcript Note:&quot;Similar to CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta (Sus scrofa)&quot; offset:0 AED:0.26 eAED:0.26 QI:0|0.84|0.92|1|0.38|0.35|14|2925|367</BlastOutput_query-def>
  <BlastOutput_query-len>4029</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056809-RA transcript Note:&quot;Similar to CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta (Sus scrofa)&quot; offset:0 AED:0.26 eAED:0.26 QI:0|0.84|0.92|1|0.38|0.35|14|2925|367</Iteration_query-def>
  <Iteration_query-len>4029</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>139.043</Hsp_bit-score>
      <Hsp_score>349</Hsp_score>
      <Hsp_evalue>2.96472e-35</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>474</Hsp_query-to>
      <Hsp_hit-from>122</Hsp_hit-from>
      <Hsp_hit-to>266</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>145</Hsp_align-len>
      <Hsp_qseq>YLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAY</Hsp_qseq>
      <Hsp_hseq>YIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSPFIAESVEGFMEECTASRY</Hsp_hseq>
      <Hsp_midline>Y+V  L TGGELF+ I++R  ++E DA   I QIL +V + H   +VHRDLKPEN+L   K + + + +ADFG+A +++G++   +  AG+ GY++PEVL +D +GKP D+W+ GVI Y LL GY PF  E      ++  A  Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>127.872</Hsp_bit-score>
      <Hsp_score>320</Hsp_score>
      <Hsp_evalue>1.44631e-31</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>474</Hsp_query-to>
      <Hsp_hit-from>112</Hsp_hit-from>
      <Hsp_hit-to>256</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>145</Hsp_align-len>
      <Hsp_qseq>YLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAY</Hsp_qseq>
      <Hsp_hseq>YIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEY</Hsp_hseq>
      <Hsp_midline>Y++  L  GGELF+ I+ +  ++E DA   + +IL +V + H   IVHRDLKPENLL   K   + + +ADFG+A  ++ D++  +  AG+ GY++PEVL +D +GKP D+W+ GVI Y LL GY  F  E       +   G Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>125.946</Hsp_bit-score>
      <Hsp_score>315</Hsp_score>
      <Hsp_evalue>1.74524e-29</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>498</Hsp_query-to>
      <Hsp_hit-from>190</Hsp_hit-from>
      <Hsp_hit-to>340</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>154</Hsp_align-len>
      <Hsp_qseq>YLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPY-GKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDQRSTVAS</Hsp_qseq>
      <Hsp_hseq>YLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNR--RIKIADFGMA-ALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMPSNLSS</Hsp_hseq>
      <Hsp_midline>YLV + V GGELF+ +V++    E +A H  +QI+E V +CH   I HRDLKPENLLL  K +   +K+ADFG+A  ++   +      G+P Y SPE++   PY G P D+W+CG++L+ LL G+ PF D++  KL  ++++G Y   S ++S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>121.709</Hsp_bit-score>
      <Hsp_score>304</Hsp_score>
      <Hsp_evalue>9.17946e-29</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>474</Hsp_query-to>
      <Hsp_hit-from>116</Hsp_hit-from>
      <Hsp_hit-to>269</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>159</Hsp_align-len>
      <Hsp_qseq>VRLHESIAEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKP-VDMWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAY</Hsp_qseq>
      <Hsp_hseq>IKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLN---VKIADFGLS-NIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVY</Hsp_hseq>
      <Hsp_midline>++L++ I  +    +V +   G ELF+ IV R+  SE +A    QQI+ +V +CH+H IVHRDLKPENLLL   +    VK+ADFGL+  +  D        G+P Y +PEV+    Y  P VD+W+CGVILY++L    PF DE    L++ I  G Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>118.627</Hsp_bit-score>
      <Hsp_score>296</Hsp_score>
      <Hsp_evalue>8.60039e-28</Hsp_evalue>
      <Hsp_query-from>28</Hsp_query-from>
      <Hsp_query-to>474</Hsp_query-to>
      <Hsp_hit-from>260</Hsp_hit-from>
      <Hsp_hit-to>437</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>180</Hsp_align-len>
      <Hsp_qseq>EGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLL---------LASKMKGA----------------------AVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAY</Hsp_qseq>
      <Hsp_hseq>DSYYYIIQELLTGGEIFGEIVRLTYFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKNTK--TPCGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTMLCGFPPFYDEKIDTLTEKISRGEY</Hsp_hseq>
      <Hsp_midline>+ ++Y++ +L+TGGE+F +IV   Y+SE  + H I+Q+  +V H H  G+VHRD+KPENLL         +  K++ +                       VKLADFGL+ ++           GT GY +PEV++ + Y   VDMW  G +LY +L G+PPF+DE    L ++I  G Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>114.39</Hsp_bit-score>
      <Hsp_score>285</Hsp_score>
      <Hsp_evalue>1.01245e-26</Hsp_evalue>
      <Hsp_query-from>31</Hsp_query-from>
      <Hsp_query-to>477</Hsp_query-to>
      <Hsp_hit-from>207</Hsp_hit-from>
      <Hsp_hit-to>374</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>170</Hsp_align-len>
      <Hsp_qseq>GFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLL---------------------ASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYD</Hsp_qseq>
      <Hsp_hseq>NYYYLVTELVTGGEIFDRIVQLTCFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLRNNTAK--TPCGTIEYVASEVFTSKRYSMKVDMWSIGCVLFTLLCGYPPFYEKNEKTLLKKISRGDYE</Hsp_hseq>
      <Hsp_midline> ++YLV +LVTGGE+F+ IV    +SE  A H I Q+  ++ H H  GIVHRD+KPENLL                              VKL DFGLA +++ +        GT  Y++ EV     Y   VDMW+ G +L+ LL GYPPF+++++  L ++I  G Y+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>111.694</Hsp_bit-score>
      <Hsp_score>278</Hsp_score>
      <Hsp_evalue>1.28601e-26</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>468</Hsp_query-to>
      <Hsp_hit-from>144</Hsp_hit-from>
      <Hsp_hit-to>280</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>143</Hsp_align-len>
      <Hsp_qseq>YLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQIKAG</Hsp_qseq>
      <Hsp_hseq>FMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLD---RNGHIKITDFGFAKEVQ---TVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQG</Hsp_hseq>
      <Hsp_midline>++V D + GGELF  +   + +    A     +++ ++ + H H I++RDLKPEN+LL    +   +K+ DFG A EVQ      +   GTP Y++PEV+   PY K VD W+ GV++Y +L GY PF+D    K Y++I  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>113.235</Hsp_bit-score>
      <Hsp_score>282</Hsp_score>
      <Hsp_evalue>2.17704e-26</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>432</Hsp_query-to>
      <Hsp_hit-from>279</Hsp_hit-from>
      <Hsp_hit-to>424</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>147</Hsp_align-len>
      <Hsp_qseq>YLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMK----------------GAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDE</Hsp_qseq>
      <Hsp_hseq>YLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLA-KFTGEMQFTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVILYVCLCGFPPFSDQ</Hsp_hseq>
      <Hsp_midline>YLV + +  GELFE IV +    + ++    +Q+L  + + H+  I+HRD+KPEN+LL    +                   VK+ADFGLA +  G+ Q      GTP Y++PEVL K  Y   VD+W+ GVILY+ L G+PPF D+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>113.235</Hsp_bit-score>
      <Hsp_score>282</Hsp_score>
      <Hsp_evalue>1.18863e-25</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>678</Hsp_query-to>
      <Hsp_hit-from>107</Hsp_hit-from>
      <Hsp_hit-to>325</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>118</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>YLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGL-AIEVQGDQQAWFGFAGTPGYLSPEVLRKDPY-GKPVDMWACGVILYILLVGYPPFWDEDQH--KLYQQIKAGAYDQRSTVASCMHRQE------TVECLRKFNARRKLKGAILTTMLATRNFSAAKSLLNKKTQ-DGVKESSESSNTTI</Hsp_qseq>
      <Hsp_hseq>YLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYN---IKIADFGMAALETEG--KLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERRIKTRDILKHPLLQKYPSIRDSKSIRGLPREDTYLTPLSESNSSIDATI</Hsp_hseq>
      <Hsp_midline>YLV +    GELF  +V R    E +A    +QI+  V +CH  GIVHRDLKPENLLL  K     +K+ADFG+ A+E +G  +      G+P Y +PE++   PY G   D+W+CGVIL+ LL G  PF +ED +   L  +++ G ++  S        Q+      TV+  R+   R  LK  +L    + R+  + + L  + T    + ES+ S + TI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>112.464</Hsp_bit-score>
      <Hsp_score>280</Hsp_score>
      <Hsp_evalue>1.62571e-25</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>474</Hsp_query-to>
      <Hsp_hit-from>257</Hsp_hit-from>
      <Hsp_hit-to>425</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>171</Hsp_align-len>
      <Hsp_qseq>VRLHESIAEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLR-------------KDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAY</Hsp_qseq>
      <Hsp_hseq>VRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQD-DPVLVKITDFGLA-KVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSY</Hsp_hseq>
      <Hsp_midline>VRL     +   +Y+V + V+GG+L + + A     E       +QIL ++ + H  GI HRDLKP+N+L+        VK+ DFGLA +VQG+      F GT  Y++PEV+R             ++ Y   VDMW+ G ++Y++L G+ PF    Q +LY+QI  G+Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>110.923</Hsp_bit-score>
      <Hsp_score>276</Hsp_score>
      <Hsp_evalue>5.67435e-25</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>103</Hsp_hit-from>
      <Hsp_hit-to>275</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>177</Hsp_align-len>
      <Hsp_qseq>YLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPY-GKPVDMWACGVILYILLVGYPPFWDEDQH--KLYQQIKAGAYDQRSTVASCMHRQETVECLRKFNARRKLK</Hsp_qseq>
      <Hsp_hseq>YLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYN---IKIADFGMA-ALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIK</Hsp_hseq>
      <Hsp_midline>YL+ +    GELF  +V      E +A +C +QI+  + +CH  GIVHRDLKPENLLL S      +K+ADFG+A  +Q D        G+P Y +PE++   PY G   D+W+CGVIL+ LL G  PF +E+ +   L  +++ G ++  +        Q+ +  +   + R+++K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>104.375</Hsp_bit-score>
      <Hsp_score>259</Hsp_score>
      <Hsp_evalue>5.11653e-24</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>459</Hsp_query-to>
      <Hsp_hit-from>161</Hsp_hit-from>
      <Hsp_hit-to>294</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>140</Hsp_align-len>
      <Hsp_qseq>YLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQI</Hsp_qseq>
      <Hsp_hseq>FMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLD---KNGHIKITDFGFAKYVP---DVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKI</Hsp_hseq>
      <Hsp_midline>+++ D + GGELF  +   + +    A     ++  ++ + H   I++RDLKPEN+LL    K   +K+ DFG A  V       +   GTP Y++PEV+   PY K +D W+ G+++Y +L GY PF+D +  K Y++I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>103.605</Hsp_bit-score>
      <Hsp_score>257</Hsp_score>
      <Hsp_evalue>9.1723e-24</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>459</Hsp_query-to>
      <Hsp_hit-from>162</Hsp_hit-from>
      <Hsp_hit-to>295</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>140</Hsp_align-len>
      <Hsp_qseq>YLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQI</Hsp_qseq>
      <Hsp_hseq>FMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLD---KNGHIKITDFGFAKYVP---DVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENI</Hsp_hseq>
      <Hsp_midline>++V D + GGELF  +   + +    A     ++  ++ + H   I++RDLKPEN+LL    K   +K+ DFG A  V       +   GTP Y++PEV+   PY K VD W+ GV++Y +L GY PF++ +  K Y+ I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>104.76</Hsp_bit-score>
      <Hsp_score>260</Hsp_score>
      <Hsp_evalue>4.4555e-23</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>537</Hsp_query-to>
      <Hsp_hit-from>187</Hsp_hit-from>
      <Hsp_hit-to>365</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>183</Hsp_align-len>
      <Hsp_qseq>RLHESIAEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKP-VDMWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDQRS----TVASCMHRQETVECLRK</Hsp_qseq>
      <Hsp_hseq>RLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISS---SGEIKIIDFGLS-NIFDYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYPSHLSIEVISLLTRMIVVDPLRR</Hsp_hseq>
      <Hsp_midline>RL E        Y++F+ V+GG+L + I+      E  A    + I  ++ + H + IVHRDLK EN++++S      +K+ DFGL+  +   ++    F G+  + +PE+L+  PY  P VD+W+ G++LY+L+ G  PF DE+   L+++IK G  D  S     V S + R   V+ LR+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>102.064</Hsp_bit-score>
      <Hsp_score>253</Hsp_score>
      <Hsp_evalue>1.7101e-22</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>459</Hsp_query-to>
      <Hsp_hit-from>421</Hsp_hit-from>
      <Hsp_hit-to>557</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>140</Hsp_align-len>
      <Hsp_qseq>YLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQI</Hsp_qseq>
      <Hsp_hseq>YFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQ---GHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKI</Hsp_hseq>
      <Hsp_midline>Y V   + GGELF  +     +  + A     ++L ++ + H+  +V+RDLKPEN+LL  +     + L DFGL      D      F GTP YL+PE+L    Y K VD W  GV+LY +L G PP++DED  K+Y++I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>101.679</Hsp_bit-score>
      <Hsp_score>252</Hsp_score>
      <Hsp_evalue>2.63665e-22</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>459</Hsp_query-to>
      <Hsp_hit-from>418</Hsp_hit-from>
      <Hsp_hit-to>554</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>140</Hsp_align-len>
      <Hsp_qseq>YLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQI</Hsp_qseq>
      <Hsp_hseq>YLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQ---GHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKI</Hsp_hseq>
      <Hsp_midline>YLV   + GGELF  +     +S A +   I ++L ++   H+  +++RDLKPEN+LL  +     + L DFGL      D      F GTP YL+PE+L    Y K VD W  G++LY ++ G PP++DE+   +Y++I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>101.293</Hsp_bit-score>
      <Hsp_score>251</Hsp_score>
      <Hsp_evalue>4.694e-22</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>468</Hsp_query-to>
      <Hsp_hit-from>489</Hsp_hit-from>
      <Hsp_hit-to>627</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>144</Hsp_align-len>
      <Hsp_qseq>YLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDP-YGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQIKAG</Hsp_qseq>
      <Hsp_hseq>YLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDA---NGNIALCDFGLSKADLKDRTN--TFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFG</Hsp_hseq>
      <Hsp_midline>YLV D ++GGELF  +     +SE  A   I +++ ++ H H + IV+RDLKPEN+LL +      + L DFGL+     D+     F GT  YL+PE+L  +  Y K VD W+ GV+++ +  G+ PF+ E+  K+YQ+I  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>101.293</Hsp_bit-score>
      <Hsp_score>251</Hsp_score>
      <Hsp_evalue>4.86331e-22</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>435</Hsp_query-to>
      <Hsp_hit-from>113</Hsp_hit-from>
      <Hsp_hit-to>255</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>147</Hsp_align-len>
      <Hsp_qseq>VRLHESIAEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPE-VLRKDPY-GKPVDMWACGVILYILLVGYPPFWDED</Hsp_qseq>
      <Hsp_hseq>VKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLD---KNENLVITDFGFVNEFCSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLP-WDDD</Hsp_hseq>
      <Hsp_midline>V+L E +    +  +V +   GGE ++ I  +    E +A     Q++  VH+ H  G+VHRDLK ENLLL    K   + + DFG   E     +      G+P Y +PE V+  +PY  +  D+W+CGVILY +L GY P WD+D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>97.8265</Hsp_bit-score>
      <Hsp_score>242</Hsp_score>
      <Hsp_evalue>5.70656e-21</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>468</Hsp_query-to>
      <Hsp_hit-from>208</Hsp_hit-from>
      <Hsp_hit-to>359</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>156</Hsp_align-len>
      <Hsp_qseq>RLHESIAEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKP-VDMWACGVILYILLVGYPPFWDEDQHKLYQQIKAG</Hsp_qseq>
      <Hsp_hseq>RLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISD---SSEIKIIDFGLS-NIYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKIKQG</Hsp_hseq>
      <Hsp_midline>RL E        Y++F+ V+GG+L + I+      E  A    + I  ++ + H + IVHRDLK EN++++     + +K+ DFGL+  +   ++    F G+  + +PE+L+ +PY  P VD+W+ GV+L++L+ G  PF DE+   L+++IK G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>92.8189</Hsp_bit-score>
      <Hsp_score>229</Hsp_score>
      <Hsp_evalue>2.06749e-20</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>178</Hsp_hit-from>
      <Hsp_hit-to>345</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>174</Hsp_align-len>
      <Hsp_qseq>YLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDQRSTVASCMHRQETVECLRKFNARRKLK</Hsp_qseq>
      <Hsp_hseq>YLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGF---NNVIKLTDFGWSI-INPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMPSNISQ--DAQDLILKLLKYDPKDRMR</Hsp_hseq>
      <Hsp_midline>YL+ + +  GE+++ +     +++  AS  I QI  ++ + H+  I+HRD+KPEN+L+        +KL DFG +I +   +       GT  YLSPE++    Y   +D WA GV+ + LL G PPF +E +   Y++I A      S ++     Q+ +  L K++ + +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.9005</Hsp_bit-score>
      <Hsp_score>237</Hsp_score>
      <Hsp_evalue>2.15343e-20</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>474</Hsp_query-to>
      <Hsp_hit-from>76</Hsp_hit-from>
      <Hsp_hit-to>247</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>175</Hsp_align-len>
      <Hsp_qseq>VRLHESIAEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEV-----------------QGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAY</Hsp_qseq>
      <Hsp_hseq>IKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLD---RDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPFRGENELKTFEKIVALDY</Hsp_hseq>
      <Hsp_midline>++L+ +  +E   Y V D   GGEL   +     +++    H   Q+++++   H HGI+HRDLKPEN+LL    +   + + DFG A  +                   D Q    F GT  Y+SPE+L  +  G   D+WA G ++Y  + G PPF  E++ K +++I A  Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.1301</Hsp_bit-score>
      <Hsp_score>235</Hsp_score>
      <Hsp_evalue>2.60389e-20</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>462</Hsp_query-to>
      <Hsp_hit-from>155</Hsp_hit-from>
      <Hsp_hit-to>294</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>143</Hsp_align-len>
      <Hsp_qseq>YLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKP--VDMWACGVILYILLVGYPPFWDEDQHKLYQQIK</Hsp_qseq>
      <Hsp_hseq>YILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYN---LKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIK</Hsp_hseq>
      <Hsp_midline>Y++ ++   G L E +  R+  +E +      QI  ++ + H   ++HRDLK  N+   S      +K+ DFGLA  +  + +  +   GTP Y++PEVL     G    VD+W+ GV+LY LL+G PPF   D + +Y++IK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.9745</Hsp_bit-score>
      <Hsp_score>232</Hsp_score>
      <Hsp_evalue>7.38665e-20</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>435</Hsp_query-to>
      <Hsp_hit-from>113</Hsp_hit-from>
      <Hsp_hit-to>255</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>147</Hsp_align-len>
      <Hsp_qseq>VRLHESIAEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPE-VLRKDPY-GKPVDMWACGVILYILLVGYPPFWDED</Hsp_qseq>
      <Hsp_hseq>IYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLD---KHENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLP-WDDD</Hsp_hseq>
      <Hsp_midline>+ L E +    +  +V + V+GGE ++ I  +    E+ A     Q++  V++ H  G+VHRDLK ENLLL    K   + + DFG   E   D +      G+P Y +PE V+    Y  +  D+W+CGVILY +L GY P WD+D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>92.0485</Hsp_bit-score>
      <Hsp_score>227</Hsp_score>
      <Hsp_evalue>1.46365e-19</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>468</Hsp_query-to>
      <Hsp_hit-from>224</Hsp_hit-from>
      <Hsp_hit-to>401</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>178</Hsp_align-len>
      <Hsp_qseq>VRLHESIAEEGFHYLVF-DLVTGGELFEDIVARE---YYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEV-----------------LRKDPYGKPVDMWACGVILYILLVGYPPFW-DEDQHKLYQQIKAG</Hsp_qseq>
      <Hsp_hseq>IKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGISPFYGDGSERSIIQNAKIG</Hsp_hseq>
      <Hsp_midline>++++ +  +   H  +F DL+ GG+LF  +   +     SE ++   + QIL+++++ H   IVHRDLK +N+LL +      + LADFG+A ++  +++      GTP Y +PEV                 L +  Y    D+W+ GVI +I+L G  PF+ D  +  + Q  K G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>89.7373</Hsp_bit-score>
      <Hsp_score>221</Hsp_score>
      <Hsp_evalue>1.35218e-18</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>459</Hsp_query-to>
      <Hsp_hit-from>188</Hsp_hit-from>
      <Hsp_hit-to>349</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>165</Hsp_align-len>
      <Hsp_qseq>RLHESIAEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEV------QGDQQAWF-------GFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQI</Hsp_qseq>
      <Hsp_hseq>KLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKNMK---VKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKV</Hsp_hseq>
      <Hsp_midline>+L  +  +E   Y + +    G+    I      +E  A +   QI+++V   H  GI+HRD+KPEN+LL   MK   VKL DFG A  +        D + +F        F GT  Y+SPE+L  +      D+WA G ILY +L G PPF   +++  +Q++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>89.3521</Hsp_bit-score>
      <Hsp_score>220</Hsp_score>
      <Hsp_evalue>2.60452e-18</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>459</Hsp_query-to>
      <Hsp_hit-from>888</Hsp_hit-from>
      <Hsp_hit-to>1036</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>158</Hsp_align-len>
      <Hsp_qseq>VRLHESIAEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFG-----FAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQI</Hsp_qseq>
      <Hsp_hseq>TNLYCSFQTENRIYFAMEFIGGGDLMWH-VQNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPE---GHIKIADYGLCKD-----EMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAI</Hsp_hseq>
      <Hsp_midline>  L+ S   E   Y   + + GG+L    V  +  S   A     ++L ++ + H +G+++RDLK EN+LL  +     +K+AD+GL  +     + W+G     F GTP +++PE+L++  Y K VD WA GV+LY +L+   PF  +D+ +++  I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.5817</Hsp_bit-score>
      <Hsp_score>218</Hsp_score>
      <Hsp_evalue>3.13961e-18</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>459</Hsp_query-to>
      <Hsp_hit-from>385</Hsp_hit-from>
      <Hsp_hit-to>554</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>173</Hsp_align-len>
      <Hsp_qseq>VRLHESIAEEGFHYLVFDLVTGGELFEDIVAREY--YSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWF------------------GFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQI</Hsp_qseq>
      <Hsp_hseq>VTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILL---HQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNI</Hsp_hseq>
      <Hsp_midline>V L+ S   + + YL  +   GGE F  +  R+    +E DA     +++ ++ + H  G ++RDLKPEN+LL    +   V L+DF L+I+  G ++                      F GT  YL+PEV+R + +   VD W  G+++Y +L G  PF  ++ ++ +  I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.4261</Hsp_bit-score>
      <Hsp_score>215</Hsp_score>
      <Hsp_evalue>9.87933e-18</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>459</Hsp_query-to>
      <Hsp_hit-from>95</Hsp_hit-from>
      <Hsp_hit-to>244</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>154</Hsp_align-len>
      <Hsp_qseq>VRLHESIAEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPY-GKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQI</Hsp_qseq>
      <Hsp_hseq>TKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSMHCVHRDLKLENILLD---KNGNAKLTDFGFTRECM-TKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKI</Hsp_hseq>
      <Hsp_midline> +L+E I  E   ++  +   G EL++ +++    S  +      QI  +V++ H    VHRDLK EN+LL    K    KL DFG   E    +       GT  Y++PE++ +  Y G  +D+W+ GVILY L+ GY PF D+D+ K   +I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.4261</Hsp_bit-score>
      <Hsp_score>215</Hsp_score>
      <Hsp_evalue>1.12224e-17</Hsp_evalue>
      <Hsp_query-from>70</Hsp_query-from>
      <Hsp_query-to>438</Hsp_query-to>
      <Hsp_hit-from>1191</Hsp_hit-from>
      <Hsp_hit-to>1309</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>124</Hsp_align-len>
      <Hsp_qseq>ELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPY-GKPVDMWACGVILYILLVGYPPFWDEDQ</Hsp_qseq>
      <Hsp_hseq>DLFDLIEFKTNMTEFEAKLIFKQVVAGIKHLHDQGIVHRDIKDENVIVDSK---GFVKIIDFGSAAYVKS--GPFDVFVGTIDYAAPEVLGGNPYEGQPQDIWAIGILLYTVVFKENPFYNIDE</Hsp_hseq>
      <Hsp_midline>+LF+ I  +   +E +A    +Q++  + H H  GIVHRD+K EN+++ SK     VK+ DFG A  V+     +  F GT  Y +PEVL  +PY G+P D+WA G++LY ++    PF++ D+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.2705</Hsp_bit-score>
      <Hsp_score>212</Hsp_score>
      <Hsp_evalue>1.1364e-17</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>423</Hsp_query-to>
      <Hsp_hit-from>79</Hsp_hit-from>
      <Hsp_hit-to>222</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>147</Hsp_align-len>
      <Hsp_qseq>VRLHESIAEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCH-QHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQ---GDQQAWFGFAGTPGYLSPEVLRKDP--YGKPVDMWACGVILYILLVGYPPF</Hsp_qseq>
      <Hsp_hseq>LRLIDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENILLD---KNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQTPW</Hsp_hseq>
      <Hsp_midline>+RL +    + + +++ ++  GG+LF+ I          A    QQ++ ++++ H + G+ HRD+KPEN+LL    K   +KLADFGLA + +   G  +      G+P Y++PEVL  +   Y    D+W+ G++L++LL G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.6557</Hsp_bit-score>
      <Hsp_score>213</Hsp_score>
      <Hsp_evalue>1.40379e-17</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>459</Hsp_query-to>
      <Hsp_hit-from>557</Hsp_hit-from>
      <Hsp_hit-to>729</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>176</Hsp_align-len>
      <Hsp_qseq>VRLHESIAEEGFHYLVFDLVTGGELFEDIVAREY--YSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIE--------VQGDQQAWF-------------GFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQI</Hsp_qseq>
      <Hsp_hseq>VTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILL---HQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNI</Hsp_hseq>
      <Hsp_midline>V L+ S   E + YL  +   GGE F  +  R+     E DA     ++  ++ + H  G ++RDLKPEN+LL    +   + L+DF L+I+        V+G  Q+                F GT  Y++PEV+R + +   VD W  G+++Y +L G+ PF  ++ ++ +  I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.1149</Hsp_bit-score>
      <Hsp_score>209</Hsp_score>
      <Hsp_evalue>4.95643e-17</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>474</Hsp_query-to>
      <Hsp_hit-from>241</Hsp_hit-from>
      <Hsp_hit-to>406</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>169</Hsp_align-len>
      <Hsp_qseq>VRLHESIAEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWF-----------GFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAY</Hsp_qseq>
      <Hsp_hseq>VRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMK---IKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKVQY</Hsp_hseq>
      <Hsp_midline>VRL  +  +E   Y + +    G+    +       E  A +   QI++++ + H +GI+HRD+KPEN+LL  +MK   +KL DFG A  +     +              F GT  Y+SPE+L         D+WA G IL+ ++ G PPF   +++  +Q++    Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.5741</Hsp_bit-score>
      <Hsp_score>205</Hsp_score>
      <Hsp_evalue>7.12343e-17</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>462</Hsp_query-to>
      <Hsp_hit-from>215</Hsp_hit-from>
      <Hsp_hit-to>375</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>164</Hsp_align-len>
      <Hsp_qseq>VRLHESIAEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQ----------QAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQIK</Hsp_qseq>
      <Hsp_hseq>VKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLL--NQRGHLV-LTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQ</Hsp_hseq>
      <Hsp_midline>V+L  S  +    YL+   + GGELF  +       E   S    +I  ++   H  G+V+RDLKPEN LL    +G  V L DFGL+ +   D            A +   GTP Y +PE+L    Y +  D ++ G +LY +LVG PP+   +   +  +I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.1889</Hsp_bit-score>
      <Hsp_score>204</Hsp_score>
      <Hsp_evalue>1.94313e-16</Hsp_evalue>
      <Hsp_query-from>61</Hsp_query-from>
      <Hsp_query-to>438</Hsp_query-to>
      <Hsp_hit-from>932</Hsp_hit-from>
      <Hsp_hit-to>1054</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>128</Hsp_align-len>
      <Hsp_qseq>TGG-ELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPY-GKPVDMWACGVILYILLVGYPPFWDEDQ</Hsp_qseq>
      <Hsp_hseq>TGSIDLFDVIEFKKDMVEHEAKLVFKQVVASIKHLHDQGIVHRDIKDENVIVDSH---GFVKLIDFGSAAYIKS--GPFDVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLYTIIYKENPYYNIDE</Hsp_hseq>
      <Hsp_midline>TG  +LF+ I  ++   E +A    +Q++ S+ H H  GIVHRD+K EN+++ S      VKL DFG A  ++     +  F GT  Y +PEVL    Y GKP D+WA GV+LY ++    P+++ D+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.1889</Hsp_bit-score>
      <Hsp_score>204</Hsp_score>
      <Hsp_evalue>1.95996e-16</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>432</Hsp_query-to>
      <Hsp_hit-from>678</Hsp_hit-from>
      <Hsp_hit-to>817</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>144</Hsp_align-len>
      <Hsp_qseq>VRLHESIAEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDE</Hsp_qseq>
      <Hsp_hseq>VNFIDSYVLKGDLWVIMEYMEGGSLT-DVVTHCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLS--MEGD-IKLTDFGFCAQINELNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPPYLNE</Hsp_hseq>
      <Hsp_midline>V   +S   +G  +++ + + GG L  D+V     +E       ++ L  +   H  G++HRD+K +N+LL+  M+G  +KL DFG   ++           GTP +++PEV+ +  YG  VD+W+ G+++  ++ G PP+ +E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.8777</Hsp_bit-score>
      <Hsp_score>198</Hsp_score>
      <Hsp_evalue>7.47916e-16</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>444</Hsp_query-to>
      <Hsp_hit-from>449</Hsp_hit-from>
      <Hsp_hit-to>589</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>144</Hsp_align-len>
      <Hsp_qseq>YLVFDLVTGGELFE--DIVAREY-------YSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHK</Hsp_qseq>
      <Hsp_hseq>WVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQ---GLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLK</Hsp_hseq>
      <Hsp_midline>+++ + + GG L +  D VAR          +E   ++ +++  + +   H   I+HRD+K +N+LL S+     VK+ DFG  +E+   +       GTP +++PE++ +  Y + VD+W+ G++L  ++ G PP+ +ED  K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.2629</Hsp_bit-score>
      <Hsp_score>199</Hsp_score>
      <Hsp_evalue>7.4958e-16</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>423</Hsp_query-to>
      <Hsp_hit-from>157</Hsp_hit-from>
      <Hsp_hit-to>289</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>138</Hsp_align-len>
      <Hsp_qseq>YLVFDLVTGGELFEDIVAREYYSEADA-SHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVL--------RKDPYG-KPVDMWACGVILYILLVGYPPF</Hsp_qseq>
      <Hsp_hseq>YIIMEYCSGGDLYEAIKADAVPKKTKSITHIITQIMDAIEYVHNKGIYHRDIKPENILISG--IDWTIKLTDWGLATT---DKTSMDRNVGSERYMSPELFDSNLDIKERKEPYDCAKVDLWAMGIVFLNIVFHKNPF</Hsp_hseq>
      <Hsp_midline>Y++ +  +GG+L+E I A     +  + +H I QI++++ + H  GI HRD+KPEN+L++       +KL D+GLA     D+ +     G+  Y+SPE+         RK+PY    VD+WA G++   ++    PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.2554</Hsp_bit-score>
      <Hsp_score>186</Hsp_score>
      <Hsp_evalue>1.58619e-14</Hsp_evalue>
      <Hsp_query-from>28</Hsp_query-from>
      <Hsp_query-to>411</Hsp_query-to>
      <Hsp_hit-from>396</Hsp_hit-from>
      <Hsp_hit-to>525</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>138</Hsp_align-len>
      <Hsp_qseq>EGFHYLVFDLVTGGELFEDIVA--REYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAW-------FGFAGTPGYLSPEVLRKDPYG-KPVDMWACGVILYILLVG</Hsp_qseq>
      <Hsp_hseq>KGEYCEVMEYCAGGDLFTLVVAAGKLEYMEADC--FFKQLIRGVVYMHEMGVCHRDLKPENLLLT---HDGVLKITDFG---NSECFKMAWEKNIHLSGGVCGSSPYIAPEEYIKEEFDPRPVDIWACGVIYMAMRTG</Hsp_hseq>
      <Hsp_midline>+G +  V +   GG+LF  +VA  +  Y EAD     +Q++  V + H+ G+ HRDLKPENLLL        +K+ DFG     +  + AW        G  G+  Y++PE   K+ +  +PVD+WACGVI   +  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.6406</Hsp_bit-score>
      <Hsp_score>187</Hsp_score>
      <Hsp_evalue>1.9748e-14</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>444</Hsp_query-to>
      <Hsp_hit-from>637</Hsp_hit-from>
      <Hsp_hit-to>775</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>143</Hsp_align-len>
      <Hsp_qseq>YLVFDLVTGGELFEDIV--------AREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHK</Hsp_qseq>
      <Hsp_hseq>WVVMEFMEGGSL-TDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTR---ARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLK</Hsp_hseq>
      <Hsp_midline>++V + + GG L  DI+        +    +E   ++ +++  + +   H   I+HRD+K +N+LL ++   A VK+ DFG    +   +       GTP +++PEV+++  Y + +D+W+ G++   +L G PP+ +ED  K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YMR291W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:852630:854390:1 gene:YMR291W transcript:YMR291W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TDA1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000004905]</Hit_def>
  <Hit_accession>YMR291W</Hit_accession>
  <Hit_len>586</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.0998</Hsp_bit-score>
      <Hsp_score>183</Hsp_score>
      <Hsp_evalue>4.09672e-14</Hsp_evalue>
      <Hsp_query-from>43</Hsp_query-from>
      <Hsp_query-to>537</Hsp_query-to>
      <Hsp_hit-from>131</Hsp_hit-from>
      <Hsp_hit-to>306</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>65</Hsp_gaps>
      <Hsp_align-len>203</Hsp_align-len>
      <Hsp_qseq>LVFDLVTGGELFEDIVAREYYS-EADASH---CIQQILESVHHCHQHGIVHRDLKPENLLLASKMK-------------------GAAVKLADFGLAIEVQGDQ-QAWFGFAGTPGYLSPEVLR--------------KDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDQRSTVASCMHRQETVECLRK</Hsp_qseq>
      <Hsp_hseq>LITQLCQKGDLYEKIVENQCLDLETQVTSYCACLVSVLEFLH---SQGIVHRDLKAENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLVLADFGLAAEYNTSKVNSLKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGCPVDIWALGVLTYFMAFGYTPF------------------------DCTTDDETLECISK</Hsp_hseq>
      <Hsp_midline>L+  L   G+L+E IV  +    E   +    C+  +LE +H     GIVHRDLK EN+L   ++                       + LADFGLA E    +  +   F GT  Y++PE+++               D YG PVD+WA GV+ Y +  GY PF                         C    ET+EC+ K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.0998</Hsp_bit-score>
      <Hsp_score>183</Hsp_score>
      <Hsp_evalue>5.9308e-14</Hsp_evalue>
      <Hsp_query-from>130</Hsp_query-from>
      <Hsp_query-to>462</Hsp_query-to>
      <Hsp_hit-from>153</Hsp_hit-from>
      <Hsp_hit-to>280</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>129</Hsp_align-len>
      <Hsp_qseq>IQQILESVHHCHQHGIVHRDLKPENLLLASKMKG------------------AAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQIK</Hsp_qseq>
      <Hsp_hseq>LQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAE-TLCGSPLYMAPEILNYQKYNAKADLWSVGTVVFEMCCGTPPFRASNHLELFKKIK</Hsp_hseq>
      <Hsp_midline>+QQ+  ++       +VHRD+KP+NLLL++ + G                    +K+ADFG A  +     A     G+P Y++PE+L    Y    D+W+ G +++ +  G PPF   +  +L+++IK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.559</Hsp_bit-score>
      <Hsp_score>179</Hsp_score>
      <Hsp_evalue>1.10455e-13</Hsp_evalue>
      <Hsp_query-from>94</Hsp_query-from>
      <Hsp_query-to>390</Hsp_query-to>
      <Hsp_hit-from>162</Hsp_hit-from>
      <Hsp_hit-to>274</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>114</Hsp_align-len>
      <Hsp_qseq>REYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMK--------------GAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEV-LRKDPYGKPVDMWACGVI</Hsp_qseq>
      <Hsp_hseq>RRVFSIPSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVE-NKNPYTAYVSTRWYRSPEILLRSGYYSKPLDIWAFGCV</Hsp_hseq>
      <Hsp_midline>R  +S       + QIL  + H H+H   HRDLKPEN+L+    +                 +KLADFGLA  V+ ++  +  +  T  Y SPE+ LR   Y KP+D+WA G +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>8.99805e-13</Hsp_evalue>
      <Hsp_query-from>16</Hsp_query-from>
      <Hsp_query-to>459</Hsp_query-to>
      <Hsp_hit-from>82</Hsp_hit-from>
      <Hsp_hit-to>229</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>153</Hsp_align-len>
      <Hsp_qseq>SIAEEGFHYLVFDLVTGGELFEDIVAREYYS---EADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVL--RKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQI</Hsp_qseq>
      <Hsp_hseq>TMLEDVSMWIVMEYCGGGSC-SDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEE---GMVKLGDFGVSGHIRSTLKR-DTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPPLSKYDPMKVMTNL</Hsp_hseq>
      <Hsp_midline>++ E+   ++V +   GG    D++ R Y +   E   S  I ++   + + H+   +HRD+K  N+LL  +     VKL DFG++  ++   +    F GTP +++PEV+    D Y +  D+W+ G+  Y LL G PP    D  K+   +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.5514</Hsp_bit-score>
      <Hsp_score>166</Hsp_score>
      <Hsp_evalue>1.03866e-12</Hsp_evalue>
      <Hsp_query-from>136</Hsp_query-from>
      <Hsp_query-to>447</Hsp_query-to>
      <Hsp_hit-from>116</Hsp_hit-from>
      <Hsp_hit-to>220</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>108</Hsp_align-len>
      <Hsp_qseq>QILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKD-PYGKPVDMWACGVILYILLVGYPPFW---DEDQHKL</Hsp_qseq>
      <Hsp_hseq>QLLQGLAFCHENKILHRDLKPQNLLIN---KRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKL</Hsp_hseq>
      <Hsp_midline>Q+L+ +  CH++ I+HRDLKP+NLL+    K   +KL DFGLA         +     T  Y +P+VL     Y   +D+W+CG IL  ++ G P F    DE+Q KL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>1.55476e-12</Hsp_evalue>
      <Hsp_query-from>103</Hsp_query-from>
      <Hsp_query-to>417</Hsp_query-to>
      <Hsp_hit-from>101</Hsp_hit-from>
      <Hsp_hit-to>203</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>106</Hsp_align-len>
      <Hsp_qseq>YSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLR-KDPYGKPVDMWACGVILYILLVGYP</Hsp_qseq>
      <Hsp_hseq>FTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSP---DGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIP</Hsp_hseq>
      <Hsp_midline>++ AD    +   L  V+HCH++ I+HRDLKP NLL +       +K+ADFGLA  +    +       T  Y +PE+L     Y   +D+W+ GVI   L++  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.3218</Hsp_bit-score>
      <Hsp_score>168</Hsp_score>
      <Hsp_evalue>2.73064e-12</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>630</Hsp_query-to>
      <Hsp_hit-from>433</Hsp_hit-from>
      <Hsp_hit-to>664</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>239</Hsp_align-len>
      <Hsp_qseq>VRLHESIAEEGFHYLVFDLVTGGELFEDIVAREYY--SEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILL---------------------VGYPPFWDEDQHKLYQQIKAGAYDQRSTVASCMHRQETV-ECLRKFN-----ARRKLKGAILTTMLATRNFSAAKSLLNKK</Hsp_qseq>
      <Hsp_hseq>LRMYDSFVHKNHLCLVFELLSNN-LYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDK-PELKIIDFGSSCE---EARTVYTYIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAELFLGIPIFPGASEYNQLTRIIDTLGYPPSWMIDMGKNSGKFMKKLAPEESSSSTQKHRMKTIEEFCREYNIVEKPSKQYFKWRKLPDII--RNYRYPKSIQNSQ</Hsp_hseq>
      <Hsp_midline>+R+++S   +    LVF+L++   L+E +   +++  S         QIL+S+    +  ++H DLKPEN+LL +  K   +K+ DFG + E   + +  + +  +  Y +PE++   PY   +DMW+ G I+  L                      +GYPP W  D  K   +       + S+ ++  HR +T+ E  R++N     +++  K   L  ++  RN+   KS+ N +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YDL028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:400997:403291:-1 gene:YDL028C transcript:YDL028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MPS1 description:Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]</Hit_def>
  <Hit_accession>YDL028C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.3218</Hsp_bit-score>
      <Hsp_score>168</Hsp_score>
      <Hsp_evalue>3.05819e-12</Hsp_evalue>
      <Hsp_query-from>133</Hsp_query-from>
      <Hsp_query-to>423</Hsp_query-to>
      <Hsp_hit-from>545</Hsp_hit-from>
      <Hsp_hit-to>654</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>114</Hsp_align-len>
      <Hsp_qseq>QQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFA--GTPGYLSPEVLRKDPY---------------GKPVDMWACGVILYILLVGYPPF</Hsp_qseq>
      <Hsp_hseq>KEMLLCIKVVHDAGIVHSDLKPANFVL---VKGI-LKIIDFGIANAVPEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYGKPPY</Hsp_hseq>
      <Hsp_midline>+++L  +   H  GIVH DLKP N +L   +KG  +K+ DFG+A  V       +     GTP Y++PE L    Y               G+P DMW+CG I+Y ++ G PP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YPR111W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:747306:749000:1 gene:YPR111W transcript:YPR111W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF20 description:Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006315]</Hit_def>
  <Hit_accession>YPR111W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.5514</Hsp_bit-score>
      <Hsp_score>166</Hsp_score>
      <Hsp_evalue>4.47662e-12</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>462</Hsp_query-to>
      <Hsp_hit-from>243</Hsp_hit-from>
      <Hsp_hit-to>420</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>43</Hsp_gaps>
      <Hsp_align-len>181</Hsp_align-len>
      <Hsp_qseq>YLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAI----------------EVQGDQQAWF------------------------GFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQIK</Hsp_qseq>
      <Hsp_hseq>YLAMEFVPGGDFRTLLINTRILKSGHARFYISEMFCAVNALHELGYTHRDLKPENFLIDA---TGHIKLTDFGLAAGTVSNERIESMKIRLEEVKNLEFPAFTERSIEDRRKIYHNMRKTEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYENLR</Hsp_hseq>
      <Hsp_midline>YL  + V GG+    ++         A   I ++  +V+  H+ G  HRDLKPEN L+ +      +KL DFGLA                 EV+  +   F                           G+P Y++ EVL    Y   VD W+ G +L+  LVGY PF     ++ Y+ ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>5.28736e-12</Hsp_evalue>
      <Hsp_query-from>43</Hsp_query-from>
      <Hsp_query-to>423</Hsp_query-to>
      <Hsp_hit-from>305</Hsp_hit-from>
      <Hsp_hit-to>445</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>145</Hsp_align-len>
      <Hsp_qseq>LVFDLVTGGELFEDIVAREYYSEADASHCIQQILE----SVHHCHQHGIVHRDLKPENLLLASKM-------------KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPY-GKPVDMWACGVILYILLVGYPPF</Hsp_qseq>
      <Hsp_hseq>MIMSYCPAGDLLAAVMARNGRLEA---WLIQRIFTEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLCKKIENNEMC-TARCGSEDYVSPEILMGVPYDGHLSDTWALGVILYSLFEDRLPF</Hsp_hseq>
      <Hsp_midline>++      G+L   ++AR    EA     IQ+I      +V + H++ I+HRDLK EN+LL                 K   ++LADFGL  +++ ++       G+  Y+SPE+L   PY G   D WA GVILY L     PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>5.82468e-12</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>462</Hsp_query-to>
      <Hsp_hit-from>251</Hsp_hit-from>
      <Hsp_hit-to>428</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>43</Hsp_gaps>
      <Hsp_align-len>181</Hsp_align-len>
      <Hsp_qseq>YLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLA-------------IEVQGDQQAWF---------------------------GFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQIK</Hsp_qseq>
      <Hsp_hseq>YLAMEFVPGGDFRTLLINTRCLKSGHARFYISEMFCAVNALHDLGYTHRDLKPENFLIDAK---GHIKLTDFGLAAGTISNERIESMKIRLEKIKDLEFPAFTEKSIEDRRKMYNQLREKEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYDNLR</Hsp_hseq>
      <Hsp_midline>YL  + V GG+    ++         A   I ++  +V+  H  G  HRDLKPEN L+ +K     +KL DFGLA             I ++  +   F                              G+P Y++ EVL    Y   VD W+ G +L+  LVGY PF     ++ Y  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>9.00142e-12</Hsp_evalue>
      <Hsp_query-from>130</Hsp_query-from>
      <Hsp_query-to>459</Hsp_query-to>
      <Hsp_hit-from>170</Hsp_hit-from>
      <Hsp_hit-to>288</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>122</Hsp_align-len>
      <Hsp_qseq>IQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLA---------IEVQGDQQAWFGFAGTPGYLSPEVLRKD---PYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQI</Hsp_qseq>
      <Hsp_hseq>VLDVVSGLEYLHSQGITHRDIKPSNLLISS---NGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPFNANSGLELFDSI</Hsp_hseq>
      <Hsp_midline>+  ++  + + H  GI HRD+KP NLL++S      VK++DFG+A         I+   +Q       GTP + +PE+   +        +D+W+ GV +Y LL G  PF      +L+  I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>9.02045e-12</Hsp_evalue>
      <Hsp_query-from>55</Hsp_query-from>
      <Hsp_query-to>423</Hsp_query-to>
      <Hsp_hit-from>308</Hsp_hit-from>
      <Hsp_hit-to>415</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>123</Hsp_align-len>
      <Hsp_qseq>LVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPF</Hsp_qseq>
      <Hsp_hseq>LKRGGRISERVIGK----------IAESVLRGLSYLHERKVIHRDIKPQNILLNEK---GEIKLCDFGVSGEAVNSLA--MTFTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRFPF</Hsp_hseq>
      <Hsp_midline>L  GG + E ++ +            + +L  + + H+  ++HRD+KP+N+LL  K     +KL DFG++ E          F GT  Y++PE ++  PY    D+W+ G+ L  +  G  PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YAR018C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:170396:171703:-1 gene:YAR018C transcript:YAR018C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN3 description:Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol [Source:SGD;Acc:S000000071]</Hit_def>
  <Hit_accession>YAR018C</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>9.62281e-12</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>477</Hsp_query-to>
      <Hsp_hit-from>100</Hsp_hit-from>
      <Hsp_hit-to>306</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>61</Hsp_gaps>
      <Hsp_align-len>207</Hsp_align-len>
      <Hsp_qseq>YLVFDLVTGGELFEDIV----AREYYSEADASHCIQQILESVHHCH---------------------QHGIVHRDLKPENLLLA-----------------------------SKMKGA-------AVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYD</Hsp_qseq>
      <Hsp_hseq>YLYMEYCSRGDLSQMIKHYKQEHKYIPEKIVWGILAQLLTALYKCHYGVELPTLTTIYDRMKPPVKGKNIVIHRDLKPGNIFLSYDDSDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLAKSLETSIQFATTYVGTPYYMSPEVLMDQPYSPLSDIWSLGCVIFEMCSLHPPFQAKNYLELQTKIKNGKCD</Hsp_hseq>
      <Hsp_midline>YL  +  + G+L + I       +Y  E      + Q+L +++ CH                     ++ ++HRDLKP N+ L+                             S  +G+        VKL DFGLA  ++   Q    + GTP Y+SPEVL   PY    D+W+ G +++ +   +PPF  ++  +L  +IK G  D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>1.16646e-11</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>447</Hsp_query-to>
      <Hsp_hit-from>103</Hsp_hit-from>
      <Hsp_hit-to>232</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>133</Hsp_align-len>
      <Hsp_qseq>IVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLA----------IEVQGDQQAWFGFAGTPGYLSPEV-LRKDPYGKPVDMWACGVILYILLVGYPPFWDED-QHKL</Hsp_qseq>
      <Hsp_hseq>VISTQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINS---NCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQL</Hsp_hseq>
      <Hsp_midline>+++ +  S+    + I Q L +V   H   ++HRDLKP NLL+ S      +K+ DFGLA           E  G Q     +  T  Y +PEV L    Y + +D+W+CG IL  L +  P F   D +H+L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>1.38806e-11</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>474</Hsp_query-to>
      <Hsp_hit-from>83</Hsp_hit-from>
      <Hsp_hit-to>235</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>VRLHESIAEEGFHYLVFDLVTGGELFEDIVAREY--YSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAY</Hsp_qseq>
      <Hsp_hseq>VKYHGFIRKSYELYILLEYCANGSL-RRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSA---DNTVKLADFGVSTIVNS---SALTLAGTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNPPYHNLTDANIYYAVENDTY</Hsp_hseq>
      <Hsp_midline>V+ H  I +    Y++ +    G L   +++R     SE ++   + Q L  + + H  G++HRD+K  N+LL++      VKLADFG++  V     +    AGT  +++PE+L         D+W+ G  +  +L   PP+ +     +Y  ++   Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>1.40592e-11</Hsp_evalue>
      <Hsp_query-from>130</Hsp_query-from>
      <Hsp_query-to>459</Hsp_query-to>
      <Hsp_hit-from>125</Hsp_hit-from>
      <Hsp_hit-to>232</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>111</Hsp_align-len>
      <Hsp_qseq>IQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDP-YGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQI</Hsp_qseq>
      <Hsp_hseq>MRELLVALKCIHKDNVIHRDIKAANVLITNE---GNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLI</Hsp_hseq>
      <Hsp_midline>++++L ++   H+  ++HRD+K  N+L+ ++     VKL DFG+A +V          AGTP +++PEV+ +   Y   VD+W+ G+  Y +  G PP+ D +  +  Q I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>1.53259e-11</Hsp_evalue>
      <Hsp_query-from>40</Hsp_query-from>
      <Hsp_query-to>459</Hsp_query-to>
      <Hsp_hit-from>220</Hsp_hit-from>
      <Hsp_hit-to>391</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>175</Hsp_align-len>
      <Hsp_qseq>YLVFDLVTGGE--------LFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGF----------AGTPGYLSPEV-LRKDPYGK----------------PVDMWACGVILYILLVGYPPFWDEDQHKLYQQI</Hsp_qseq>
      <Hsp_hseq>YLVLEYCSRGEVKWCPPDCMESDAKGPSLLSFQETREILRGVVLGLEYLHYQGIIHRDIKPANLLISG---DGTVKISDFGVSLAASSTNSSDSSESLDELELAKTVGTPAFFAPEMCLGEDAFTRYNLTKENLFRGSCISFMIDIWAVGVTLYCLLFGMLPFFSDFELKLFEKI</Hsp_hseq>
      <Hsp_midline>YLV +  + GE        +  D       S  +    ++ ++  + + H  GI+HRD+KP NLL++       VK++DFG+++       +               GTP + +PE+ L +D + +                 +D+WA GV LY LL G  PF+ + + KL+++I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YKL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:347214:349136:-1 gene:YKL048C transcript:YKL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ELM1 description:Serine/threonine protein kinase; regulates the orientation checkpoint, the morphogenesis checkpoint and the metabolic switch from fermentative to oxidative metabolism by phosphorylating the activation loop of Kin4p, Hsl1p and Snf4p respectively; cooperates with Hsl7p in recruiting Hsl1p to the septin ring, a prerequisite for subsequent recruitment, phosphorylation, and degradation of Swe1p; forms part of the bud neck ring; regulates cytokinesis [Source:SGD;Acc:S000001531]</Hit_def>
  <Hit_accession>YKL048C</Hit_accession>
  <Hit_len>640</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>5.31375e-11</Hsp_evalue>
      <Hsp_query-from>118</Hsp_query-from>
      <Hsp_query-to>459</Hsp_query-to>
      <Hsp_hit-from>236</Hsp_hit-from>
      <Hsp_hit-to>366</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>133</Hsp_align-len>
      <Hsp_qseq>ASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGD------------QQAWFGFAGTPGYLSPEVL-----RKD--PYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQI</Hsp_qseq>
      <Hsp_hseq>AKKILEDMTKGLEYLHSQGCIHRDIKPSNILLDEEEKVA--KLSDFGSCIFTPQSLPFSDANFEDCFQRELNKIVGTPAFIAPELCHLGNSKRDFVTDGFKLDIWSLGVTLYCLLYNELPFFGENEFETYHKI</Hsp_hseq>
      <Hsp_midline>A   ++ + + + + H  G +HRD+KP N+LL  + K A  KL+DFG  I                 Q+      GTP +++PE+      ++D    G  +D+W+ GV LY LL    PF+ E++ + Y +I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>6.01986e-11</Hsp_evalue>
      <Hsp_query-from>10</Hsp_query-from>
      <Hsp_query-to>438</Hsp_query-to>
      <Hsp_hit-from>513</Hsp_hit-from>
      <Hsp_hit-to>662</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>153</Hsp_align-len>
      <Hsp_qseq>HESI------AEEGFHYLVF-DLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIE---VQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQ</Hsp_qseq>
      <Hsp_hseq>HENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIK---GCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQ</Hsp_hseq>
      <Hsp_midline>HE+I      ++EG +  +F + V GG +   +     + E+  ++  +QIL  V + H+  I+HRD+K  N+L+  K     VK+ DFG++ +   +   Q       G+  ++SPEV+++       D+W+ G ++  +  G  PF D  Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>8.0719e-11</Hsp_evalue>
      <Hsp_query-from>106</Hsp_query-from>
      <Hsp_query-to>465</Hsp_query-to>
      <Hsp_hit-from>139</Hsp_hit-from>
      <Hsp_hit-to>265</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>133</Hsp_align-len>
      <Hsp_qseq>SEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWF-----------GFAGTPGYLSPEVLRKD-PYGKPVDMWACGVILYILLVGYPPFWDED-QHKLYQQIKA</Hsp_qseq>
      <Hsp_hseq>SEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCT---LNGCLKICDFGLA---RGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKV</Hsp_hseq>
      <Hsp_midline>SE    + + QIL  + + H   ++HRDLKP N+L         +K+ DFGLA   +G    +F            +  T  Y +PE+L  + PY K VD+WA G IL       P F   D  H++++ IK </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YJL165C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:106894:109461:-1 gene:YJL165C transcript:YJL165C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HAL5 description:Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters; HAL5 has a paralog, KKQ8, that arose from the whole genome duplication [Source:SGD;Acc:S000003701]</Hit_def>
  <Hit_accession>YJL165C</Hit_accession>
  <Hit_len>855</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>2.14733e-10</Hsp_evalue>
      <Hsp_query-from>130</Hsp_query-from>
      <Hsp_query-to>411</Hsp_query-to>
      <Hsp_hit-from>669</Hsp_hit-from>
      <Hsp_hit-to>765</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>53</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>103</Hsp_align-len>
      <Hsp_qseq>IQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAW-------FGFAGTPGYLSPEVLRKDPYGKP--VDMWACGVILYILLVG</Hsp_qseq>
      <Hsp_hseq>MKQLLNGVQYMHDHGIAHCDLKPENILF---QPNGLLKICDFGTSSVF---QTAWEKHVHFQSGAMGSEPYVAPEEFIRDAEYDPRLVDCWSCGIVYCTMVMG</Hsp_hseq>
      <Hsp_midline>++Q+L  V + H HGI H DLKPEN+L         +K+ DFG +      Q AW        G  G+  Y++PE   +D    P  VD W+CG++   +++G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YJR059W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:545787:548243:1 gene:YJR059W transcript:YJR059W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK2 description:Serine/threonine protein kinase; involved in regulation of ion transport across plasma membrane; carboxyl terminus is essential for glucose-dependent Pma1p activation via phosphorylation of Pma1p-Ser899; enhances spermine uptake; PTK2 has a paralog, PTK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003820]</Hit_def>
  <Hit_accession>YJR059W</Hit_accession>
  <Hit_len>818</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>2.27287e-10</Hsp_evalue>
      <Hsp_query-from>124</Hsp_query-from>
      <Hsp_query-to>429</Hsp_query-to>
      <Hsp_hit-from>366</Hsp_hit-from>
      <Hsp_hit-to>484</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>122</Hsp_align-len>
      <Hsp_qseq>HCI-QQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAI-------EVQGDQQAWFGFAGTPGYLSPEVLRKD-----------PYGK-PVDMWACGVILYILLVGYPPFWD</Hsp_qseq>
      <Hsp_hseq>YCLFKQVAQGIKFCHDNGIAHRDLKPENVLIS---KEGICKLTDFGISDWYHVIPHDYTSPVKTCQGMIGSPPYTPPEVMYFDAKKHYPEKFQKPYNPLAMDSYALGIMLITMINNIIPFID</Hsp_hseq>
      <Hsp_midline>+C+ +Q+ + +  CH +GI HRDLKPEN+L++   K    KL DFG++        +     +   G  G+P Y  PEV+  D           PY    +D +A G++L  ++    PF D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>2.9833e-10</Hsp_evalue>
      <Hsp_query-from>94</Hsp_query-from>
      <Hsp_query-to>423</Hsp_query-to>
      <Hsp_hit-from>299</Hsp_hit-from>
      <Hsp_hit-to>404</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>111</Hsp_align-len>
      <Hsp_qseq>REYYSEADASHCIQQILESVHHCH-QHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPF</Hsp_qseq>
      <Hsp_hseq>KTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSK---GQIKLCDFGVSKKLIN--SIADTFVGTSTYMSPERIQGNVYSIKGDVWSLGLMIIELVTGEFPL</Hsp_hseq>
      <Hsp_midline>+ +++E   S     +L  + H + Q+ I+HRD+KP N+L+ SK     +KL DFG++ ++         F GT  Y+SPE ++ + Y    D+W+ G+++  L+ G  P </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>3.27274e-10</Hsp_evalue>
      <Hsp_query-from>130</Hsp_query-from>
      <Hsp_query-to>435</Hsp_query-to>
      <Hsp_hit-from>125</Hsp_hit-from>
      <Hsp_hit-to>221</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>103</Hsp_align-len>
      <Hsp_qseq>IQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEV-LRKDPYGKPVDMWACGVILYILLVGYPPFWDED</Hsp_qseq>
      <Hsp_hseq>LYQILRGLKYVHSAGVIHRDLKPSNILIN---ENCDLKICDFGLA-RIQDPQMT--GYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKD</Hsp_hseq>
      <Hsp_midline>+ QIL  + + H  G++HRDLKP N+L+    +   +K+ DFGLA  +Q  Q    G+  T  Y +PE+ L    Y   VD+W+ G I   ++ G P F  +D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>3.71233e-10</Hsp_evalue>
      <Hsp_query-from>136</Hsp_query-from>
      <Hsp_query-to>441</Hsp_query-to>
      <Hsp_hit-from>126</Hsp_hit-from>
      <Hsp_hit-to>232</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>110</Hsp_align-len>
      <Hsp_qseq>QILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLA---IEVQGDQQAWFGF----AGTPGYLSPEV-LRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQH</Hsp_qseq>
      <Hsp_hseq>QILRALKSIHSAQVIHRDIKPSNLLLNS---NCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYH</Hsp_hseq>
      <Hsp_midline>QIL ++   H   ++HRD+KP NLLL S      +K+ DFGLA         ++   GF      T  Y +PE+ L    Y   +D+W+CG IL  ++ G P F   D H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YKL168C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:131288:133462:-1 gene:YKL168C transcript:YKL168C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KKQ8 description:Putative serine/threonine protein kinase with unknown cellular role; KKQ8 has a paralog, HAL5, that arose from the whole genome duplication [Source:SGD;Acc:S000001651]</Hit_def>
  <Hit_accession>YKL168C</Hit_accession>
  <Hit_len>724</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>5.84288e-10</Hsp_evalue>
      <Hsp_query-from>46</Hsp_query-from>
      <Hsp_query-to>414</Hsp_query-to>
      <Hsp_hit-from>512</Hsp_hit-from>
      <Hsp_hit-to>641</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>135</Hsp_align-len>
      <Hsp_qseq>VFDLVTGGELFEDIVA------REYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQ----AWFGFAGTPGYLSPEVLRKDPYGKP--VDMWACGVILYILLVGY</Hsp_qseq>
      <Hsp_hseq>VMEFCPAGDLYGMLVGKSKLKGRLHPLEADC--FMKQLLHGVKFMHDHGIAHCDLKPENILF---YPHGLLKICDFGTSSVFQTAWERRVHAQKGIIGSEPYVAPEEFVDGEYYDPRLIDCWSCGVVYITMILGH</Hsp_hseq>
      <Hsp_midline>V +    G+L+  +V       R +  EAD    ++Q+L  V   H HGI H DLKPEN+L         +K+ DFG +   Q   +    A  G  G+  Y++PE      Y  P  +D W+CGV+   +++G+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>9.18628e-10</Hsp_evalue>
      <Hsp_query-from>55</Hsp_query-from>
      <Hsp_query-to>393</Hsp_query-to>
      <Hsp_hit-from>315</Hsp_hit-from>
      <Hsp_hit-to>412</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>113</Hsp_align-len>
      <Hsp_qseq>LVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVIL</Hsp_qseq>
      <Hsp_hseq>LERGGRISEKVLGK----------IAEAVLRGLSYLHEKKVIHRDIKPQNILLN---ENGQVKLCDFGVSGEAVNSLAT--TFTGTSFYMAPERIQGQPYSVTSDVWSLGLTI</Hsp_hseq>
      <Hsp_midline>L  GG + E ++ +            + +L  + + H+  ++HRD+KP+N+LL    +   VKL DFG++ E          F GT  Y++PE ++  PY    D+W+ G+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YNL183C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:293137:295509:-1 gene:YNL183C transcript:YNL183C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NPR1 description:Protein kinase; stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p; negatively regulates Ldb19p-mediated endocytosis through phosphorylation of Ldb19p, which prevents its association with the plasma membrane; Npr1p activity is negatively regulated via phosphorylation by the TOR complex; NPR1 has a paralog, PRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005127]</Hit_def>
  <Hit_accession>YNL183C</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>1.21498e-09</Hsp_evalue>
      <Hsp_query-from>127</Hsp_query-from>
      <Hsp_query-to>450</Hsp_query-to>
      <Hsp_hit-from>541</Hsp_hit-from>
      <Hsp_hit-to>654</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>119</Hsp_align-len>
      <Hsp_qseq>CIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAI----EVQGDQQAWFGFAGTPGYLSPEVL---RKDPYGKPVDMWACGVILY-ILLVGYP---PFWDEDQHKLY</Hsp_qseq>
      <Hsp_hseq>CFKQILTGVQYLHSIGLAHRDLKLDNCVINEK---GIVKLIDFGAAVVFSYPFSKNLVEASGIVGSDPYLAPEVCIFAKYDP--RPVDIWSSAIIFACMILKKFPWKIPKLRDNSFKLF</Hsp_hseq>
      <Hsp_midline>C +QIL  V + H  G+ HRDLK +N ++  K     VKL DFG A+        +     G  G+  YL+PEV    + DP  +PVD+W+  +I   ++L  +P   P   ++  KL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>1.24755e-09</Hsp_evalue>
      <Hsp_query-from>124</Hsp_query-from>
      <Hsp_query-to>459</Hsp_query-to>
      <Hsp_hit-from>814</Hsp_hit-from>
      <Hsp_hit-to>957</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>147</Hsp_align-len>
      <Hsp_qseq>HCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEV-------QGDQQAWFGFA-------GTPGYLSPEVLR-KDPYGKPVDMWACGVILYILL--------------------VGYPPFWDEDQHKLYQQI</Hsp_qseq>
      <Hsp_hseq>RLFRQILEALSYIHSQGIIHRDLKPMNIFID---ESRNVKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVLDGTGHYNEKIDMYSLGIIFFEMIYPFSTGMERVNILKKLRSVSIEFPPDFDDNKMKVEKKI</Hsp_hseq>
      <Hsp_midline>   +QILE++ + H  GI+HRDLKP N+ +    +   VK+ DFGLA  V       + D Q   G +       GT  Y++ EVL     Y + +DM++ G+I + ++                    + +PP +D+++ K+ ++I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YKL198C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:68232:70220:-1 gene:YKL198C transcript:YKL198C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK1 description:Putative serine/threonine protein kinase; regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein; PTK1 has a paralog, PTK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001681]</Hit_def>
  <Hit_accession>YKL198C</Hit_accession>
  <Hit_len>662</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>1.28222e-09</Hsp_evalue>
      <Hsp_query-from>127</Hsp_query-from>
      <Hsp_query-to>423</Hsp_query-to>
      <Hsp_hit-from>308</Hsp_hit-from>
      <Hsp_hit-to>423</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>119</Hsp_align-len>
      <Hsp_qseq>CI-QQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQ-------QAWFGFAGTPGYLSPEVLRKD-----------PYG-KPVDMWACGVILYILLVGYPPF</Hsp_qseq>
      <Hsp_hseq>CIFKQVACGVKFCHDQGIAHRDLKPENVLLS---PDGVCKLTDFGISDWYHTDPHDLSSPVKKCAGMIGSPPYAPPEVMFYDSKKHYDTELQQPYDPRALDCYGLGIILMTLVNNVIPF</Hsp_hseq>
      <Hsp_midline>CI +Q+   V  CH  GI HRDLKPEN+LL+        KL DFG++     D        +   G  G+P Y  PEV+  D           PY  + +D +  G+IL  L+    PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>71</Hit_num>
  <Hit_id>YOR267C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:822588:824867:-1 gene:YOR267C transcript:YOR267C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRK1 description:Protein kinase; implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005793]</Hit_def>
  <Hit_accession>YOR267C</Hit_accession>
  <Hit_len>759</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>2.03864e-09</Hsp_evalue>
      <Hsp_query-from>76</Hsp_query-from>
      <Hsp_query-to>450</Hsp_query-to>
      <Hsp_hit-from>303</Hsp_hit-from>
      <Hsp_hit-to>434</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>135</Hsp_align-len>
      <Hsp_qseq>FEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAI----EVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKP--VDMWACGVI-LYILLVGYP---PFWDEDQHKLY</Hsp_qseq>
      <Hsp_hseq>FFAVVMTGKMSRGEINCCLKQLTEGVKYLHSMGLAHRDLKLDNCVMTSQ---GILKLIDFGSAVVFRYPFEDGVTMAHGIVGSDPYLAPEVITSTKSYDPQCVDIWSIGIIYCCMVLKRFPWKAPRDSDDNFRLY</Hsp_hseq>
      <Hsp_midline>F  +V     S  + + C++Q+ E V + H  G+ HRDLK +N ++ S+     +KL DFG A+      +       G  G+  YL+PEV+       P  VD+W+ G+I   ++L  +P   P   +D  +LY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>72</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>2.38058e-09</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>393</Hsp_query-to>
      <Hsp_hit-from>71</Hsp_hit-from>
      <Hsp_hit-to>202</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>135</Hsp_align-len>
      <Hsp_qseq>VRLHESIAEEGFH-YLVFDLVTGG--ELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLR-KDPYGKPVDMWACGVIL</Hsp_qseq>
      <Hsp_hseq>VRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLIN---KDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIF</Hsp_hseq>
      <Hsp_midline>VRL++ +  +    YLVF+ +        E I   +          + Q+ + + +CH H I+HRDLKP+NLL+    K   +KL DFGLA       +A+     T  Y +PEVL     Y   VD W+ G I </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>73</Hit_num>
  <Hit_id>YDL025C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:405344:407206:-1 gene:YDL025C transcript:YDL025C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RTK1 description:Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002183]</Hit_def>
  <Hit_accession>YDL025C</Hit_accession>
  <Hit_len>620</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>3.07413e-09</Hsp_evalue>
      <Hsp_query-from>10</Hsp_query-from>
      <Hsp_query-to>423</Hsp_query-to>
      <Hsp_hit-from>366</Hsp_hit-from>
      <Hsp_hit-to>510</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>149</Hsp_align-len>
      <Hsp_qseq>HESIAE------EGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWF----GFAGTPGYLSPEVLRKDPYGKPV-DMWACGVILYILLVGYPPF</Hsp_qseq>
      <Hsp_hseq>HENIVETLDMLTEGDTYLLVMEYAPYDFF-NLVMSNLMTQDEVNCYFKQLCHGVNYLHSMGLAHRDLKLDNCVVT---KDGILKLIDFGSAVVFQYPYEDTIVKSHGIVGSDPYLAPELLKQTSYDPRVADVWSIAIIFYCMVLKRFPW</Hsp_hseq>
      <Hsp_midline>HE+I E      EG  YL+       + F ++V     ++ + +   +Q+   V++ H  G+ HRDLK +N ++    K   +KL DFG A+  Q   +       G  G+  YL+PE+L++  Y   V D+W+  +I Y +++   P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>74</Hit_num>
  <Hit_id>YFL033C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:69115:74427:-1 gene:YFL033C transcript:YFL033C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM15 description:Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase [Source:SGD;Acc:S000001861]</Hit_def>
  <Hit_accession>YFL033C</Hit_accession>
  <Hit_len>1770</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>1.10235e-08</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>264</Hsp_query-to>
      <Hsp_hit-from>856</Hsp_hit-from>
      <Hsp_hit-to>940</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>88</Hsp_align-len>
      <Hsp_qseq>VRLHESIAEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLA</Hsp_qseq>
      <Hsp_hseq>ARLFASFQNKDNLFLVMEYLPGGDLATLIKMMGYLPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLIDN---AGHVKLTDFGLS</Hsp_hseq>
      <Hsp_midline> RL  S   +   +LV + + GG+L   I    Y  +  A   + +I+  V+  HQ+GI+H DLKPENLL+ +      VKL DFGL+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>4.70231e-07</Hsp_evalue>
      <Hsp_query-from>259</Hsp_query-from>
      <Hsp_query-to>468</Hsp_query-to>
      <Hsp_hit-from>1133</Hsp_hit-from>
      <Hsp_hit-to>1203</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>39</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>71</Hsp_align-len>
      <Hsp_qseq>LAIEVQGDQQAWFGFAGTPGYLSPEVLR-KDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQIKAG</Hsp_qseq>
      <Hsp_hseq>LALFYPDDSKQNKKFFGTPDYLAPETIEGKGEDNKQCDWWSVGCIFFELLLGYPPFHAETPDAVFKKILSG</Hsp_hseq>
      <Hsp_midline>LA+    D +    F GTP YL+PE +  K    K  D W+ G I + LL+GYPPF  E    ++++I +G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>75</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>1.11134e-08</Hsp_evalue>
      <Hsp_query-from>136</Hsp_query-from>
      <Hsp_query-to>441</Hsp_query-to>
      <Hsp_hit-from>1141</Hsp_hit-from>
      <Hsp_hit-to>1258</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>121</Hsp_align-len>
      <Hsp_qseq>QILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAW--------FG--------FAGTPGYLSPEVLRKDPYGKPV---DMWACGVILYILLVGYPPFWDEDQH</Hsp_qseq>
      <Hsp_hseq>ELLEGLAYLHQSGVVHRDIKPENILLDF---NGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPWSNLDNE</Hsp_hseq>
      <Hsp_midline>++LE + + HQ G+VHRD+KPEN+LL        +K  DFG A  V G +           FG          GTP Y++PE +        +   D+WA G ++  +  G  P+ + D  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>76</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>1.35476e-08</Hsp_evalue>
      <Hsp_query-from>43</Hsp_query-from>
      <Hsp_query-to>423</Hsp_query-to>
      <Hsp_hit-from>1255</Hsp_hit-from>
      <Hsp_hit-to>1380</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>129</Hsp_align-len>
      <Hsp_qseq>LVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQG-DQQAWFGFAGTPGYLSPEVL-RKDPYGKPVDMWACGVILYILLVGYPPF</Hsp_qseq>
      <Hsp_hseq>LFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLD---QDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPW</Hsp_hseq>
      <Hsp_midline>L  + V GG +   I     + E    H   Q+L+ + + H  GI+HRD+K +NLLL    +    K++DFG++ + +     +     GT  +++PE++  K  Y   VD+W+ G I+  +  G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>77</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>2.04601e-08</Hsp_evalue>
      <Hsp_query-from>106</Hsp_query-from>
      <Hsp_query-to>405</Hsp_query-to>
      <Hsp_hit-from>279</Hsp_hit-from>
      <Hsp_hit-to>375</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>53</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>101</Hsp_align-len>
      <Hsp_qseq>SEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLR-KDPYGKPVDMWACGVILYILL</Hsp_qseq>
      <Hsp_hseq>SHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQ---GNLKITDFGLARKM-NSRADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELF</Hsp_hseq>
      <Hsp_midline>S +   H  +Q+L  + + H + I+HRD+K  N+L+ ++     +K+ DFGLA ++   +  +     T  Y  PE+L     YG  VDMW CG +L  L </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>78</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>4.51713e-08</Hsp_evalue>
      <Hsp_query-from>136</Hsp_query-from>
      <Hsp_query-to>459</Hsp_query-to>
      <Hsp_hit-from>136</Hsp_hit-from>
      <Hsp_hit-to>245</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>113</Hsp_align-len>
      <Hsp_qseq>QILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQ----GDQQAWFGFAGTPGYLSPEV-LRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQI</Hsp_qseq>
      <Hsp_hseq>QILCGLKYIHSADVLHRDLKPGNLLVNADCQ---LKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQI</Hsp_hseq>
      <Hsp_midline>QIL  + + H   ++HRDLKP NLL+ +  +   +K+ DFGLA         + Q    +  T  Y +PE+ L    Y K +D+W+ G IL   L G P F  +D      QI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>79</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>8.64335e-08</Hsp_evalue>
      <Hsp_query-from>136</Hsp_query-from>
      <Hsp_query-to>447</Hsp_query-to>
      <Hsp_hit-from>269</Hsp_hit-from>
      <Hsp_hit-to>372</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>108</Hsp_align-len>
      <Hsp_qseq>QILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWF---GFAGTPGYLSPEVLRKDPYGKP-VDMWACGVILYILLVGYPPFWDEDQHKL</Hsp_qseq>
      <Hsp_hseq>QLLDGVSYLHQNWVLHRDLKPANIMVTI---DGCVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCI-FAELIGLQPIFKGEEAKL</Hsp_hseq>
      <Hsp_midline>Q+L+ V + HQ+ ++HRDLKP N+++        VK+ D GLA +     Q  +       T  Y +PE+L    +  P VD+W+ G I +  L+G  P +  ++ KL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>80</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>9.59808e-08</Hsp_evalue>
      <Hsp_query-from>295</Hsp_query-from>
      <Hsp_query-to>459</Hsp_query-to>
      <Hsp_hit-from>569</Hsp_hit-from>
      <Hsp_hit-to>623</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>33</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>55</Hsp_align-len>
      <Hsp_qseq>FGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQI</Hsp_qseq>
      <Hsp_hseq>YSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKI</Hsp_hseq>
      <Hsp_midline>+   GTP Y++PE+     YG+  D W+ G I+Y  L+G+PPF  E   + Y++I</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>1.654e-07</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>264</Hsp_query-to>
      <Hsp_hit-from>413</Hsp_hit-from>
      <Hsp_hit-to>497</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>88</Hsp_align-len>
      <Hsp_qseq>VRLHESIAEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLA</Hsp_qseq>
      <Hsp_hseq>VSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIR---GHIKLSDFGLS</Hsp_hseq>
      <Hsp_midline>V L+ S  +  + YL+ + + GG+L   ++  + ++E      + + + ++   H+ G +HRD+KP+N+L+  +     +KL+DFGL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>81</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>9.63059e-08</Hsp_evalue>
      <Hsp_query-from>136</Hsp_query-from>
      <Hsp_query-to>438</Hsp_query-to>
      <Hsp_hit-from>1373</Hsp_hit-from>
      <Hsp_hit-to>1505</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>QILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLA---------------IE-----------------VQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPV---DMWACGVILYILLVGYPPFWDEDQ</Hsp_qseq>
      <Hsp_hseq>QLLEGLAYLHESGIVHRDVKPENILLDF---NGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPWANLDN</Hsp_hseq>
      <Hsp_midline>Q+LE + + H+ GIVHRD+KPEN+LL        +K  DFG A               IE                 V+ ++ A     GTP Y++PE +        +   D+W+ G ++  ++ G  P+ + D </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>82</Hit_num>
  <Hit_id>YDR247W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:956013:957398:1 gene:YDR247W transcript:YDR247W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VHS1 description:Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; VHS1 has a paralog, SKS1, that arose from the whole genome duplication [Source:SGD;Acc:S000002655]</Hit_def>
  <Hit_accession>YDR247W</Hit_accession>
  <Hit_len>461</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>1.2523e-07</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>438</Hsp_query-to>
      <Hsp_hit-from>122</Hsp_hit-from>
      <Hsp_hit-to>279</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>164</Hsp_align-len>
      <Hsp_qseq>VRLHESIAEEGFHYLVFDLVTGGELFEDIVAREYYSEAD--ASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKD-----------PYGKPV-----DMWACGVILYILLVGYPPFWDEDQ</Hsp_qseq>
      <Hsp_hseq>VTIHEVLQSAVCTFIVMDYYPT-DLFTSIVDNRHFVTNGLLVKKVFLQICSALNYCHEHGIYHCDIKPENLLLDTE---DNVFLCDFGLSTTSTYIKPNV--CIGSSYYMPPERISFDGRVSSSKSGGHKLGKVCPSCNGDLWSLGIILINLTCIRNPWLKADK</Hsp_hseq>
      <Hsp_midline>V +HE +      ++V D     +LF  IV   ++            QI  ++++CH+HGI H D+KPENLLL ++     V L DFGL+      +       G+  Y+ PE +  D             GK       D+W+ G+IL  L     P+   D+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>83</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>1.66555e-07</Hsp_evalue>
      <Hsp_query-from>28</Hsp_query-from>
      <Hsp_query-to>570</Hsp_query-to>
      <Hsp_hit-from>428</Hsp_hit-from>
      <Hsp_hit-to>617</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>202</Hsp_align-len>
      <Hsp_qseq>EGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQ-----ILESVHHC-----HQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFA--GTPGYLSPEVLR-----KDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQIKA---GAYDQRSTVASCMHRQETVE-CLRKFNARRKLKGAI</Hsp_qseq>
      <Hsp_hseq>EGAVYMCMEYMDGGSL------DKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSANQ--GTVKLCDFG----VSGNLVASLAKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYPPETYDNIFSQLSAIVDGPPPRLPSDKFSSDAQDFVSLCLQKIPERRPTYAAL</Hsp_hseq>
      <Hsp_midline>EG  Y+  + + GG L       + Y E+     I +     I  +V H       QH I+HRD+KP N+L ++      VKL DFG    V G+  A       G   Y++PE ++     +  Y    D+W+ G+ +  + +G  P+  E    ++ Q+ A   G   +  +       Q+ V  CL+K   RR    A+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>84</Hit_num>
  <Hit_id>YDL214C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:74446:76545:-1 gene:YDL214C transcript:YDL214C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR2 description:Serine/threonine protein kinase; inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance; PRR2 has a paralog, NPR1, that arose from the whole genome duplication [Source:SGD;Acc:S000002373]</Hit_def>
  <Hit_accession>YDL214C</Hit_accession>
  <Hit_len>699</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>2.62418e-07</Hsp_evalue>
      <Hsp_query-from>133</Hsp_query-from>
      <Hsp_query-to>423</Hsp_query-to>
      <Hsp_hit-from>466</Hsp_hit-from>
      <Hsp_hit-to>564</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>102</Hsp_align-len>
      <Hsp_qseq>QQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLA----IEVQGDQQAWFGFAGTPGYLSPEVLRKDPYG-KPVDMWACGVILYILLVGYPPF</Hsp_qseq>
      <Hsp_hseq>KQLINGVKYLHDIGLSHRDLKLDNCVVTRR---GILKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFYFNEYDPRALDVWSVGIIFFCMITRRFPW</Hsp_hseq>
      <Hsp_midline>+Q++  V + H  G+ HRDLK +N ++  +     +KL DFG +      +        G  G+  YLSPEV   + Y  + +D+W+ G+I + ++    P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>85</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>3.5763e-07</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>411</Hsp_query-to>
      <Hsp_hit-from>70</Hsp_hit-from>
      <Hsp_hit-to>218</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>157</Hsp_align-len>
      <Hsp_qseq>AEEGFHYLVFDLVTGGELFEDI-VAREYYS-------EADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEV--QGDQQAWFGFAGTPGYLSPEVLRK-----------DPYGKPV------DMWACGVILYILLVG</Hsp_qseq>
      <Hsp_hseq>TDDSYYIMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQIDMQKIIKQLCSAISFAHSLGIAHRDIKPENILLTI---NGDIKLADWGHAIQSPKSNDFQ-----IGTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFG</Hsp_hseq>
      <Hsp_midline> ++ ++ +V +    G+L++ + +A+   S       + D    I+Q+  ++   H  GI HRD+KPEN+LL        +KLAD+G AI+     D Q      GT  Y +PE               D    P+      D W+ G  ++ L+ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>86</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>5.7647e-07</Hsp_evalue>
      <Hsp_query-from>70</Hsp_query-from>
      <Hsp_query-to>435</Hsp_query-to>
      <Hsp_hit-from>114</Hsp_hit-from>
      <Hsp_hit-to>237</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>127</Hsp_align-len>
      <Hsp_qseq>ELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGF----AGTPGYLSPEVLRK-DPYGKPVDMWACGVILYILLVGYPPFWDED</Hsp_qseq>
      <Hsp_hseq>DLSQIIRSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQ---LKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFEGKD</Hsp_hseq>
      <Hsp_midline>+L + I + +   +A     I QIL ++ + H   ++H DLKP+NLL+ S  +   +K+ +FGL+     + +   GF      +  Y +PE+L       K VD+W+ G IL  LL   P F  +D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>87</Hit_num>
  <Hit_id>YHR079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:258244:261591:-1 gene:YHR079C transcript:YHR079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IRE1 description:Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; role in homeostatic adaptation to ER stress; Kar2p binds inactive Ire1p and releases from it upon ER stress [Source:SGD;Acc:S000001121]</Hit_def>
  <Hit_accession>YHR079C</Hit_accession>
  <Hit_len>1115</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>7.8429e-07</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>432</Hsp_query-to>
      <Hsp_hit-from>729</Hsp_hit-from>
      <Hsp_hit-to>924</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>56</Hsp_gaps>
      <Hsp_align-len>198</Hsp_align-len>
      <Hsp_qseq>VRLHESIAEEGFHYLVFDLVTGGELFEDIVAREYYS--------EADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAA----------VKLADFGLAIEVQGDQQAWF----GFAGTPGYLSPEVLRK--------------------------DPYGK-----PVDMWACG-VILYILLVGYPPFWDE</Hsp_qseq>
      <Hsp_hseq>IRYYCSETTDRFLYIALELCNLN--LQDLVESKNVSDENLKLQKEYNPISLLRQIASGVAHLHSLKIIHRDLKPQNILVSTSSRFTADQQTGAENLRILISDFGLCKKLDSGQSSFRTNLNNPSGTSGWRAPELLEESNNLQCQVETEHSSSRHTVVSSDSFYDPFTKRRLTRSIDIFSMGCVFYYILSKGKHPFGDK</Hsp_hseq>
      <Hsp_midline>+R + S   + F Y+  +L       +D+V  +  S        E +    ++QI   V H H   I+HRDLKP+N+L+++  +  A          + ++DFGL  ++   Q ++       +GT G+ +PE+L +                          DP+ K      +D+++ G V  YIL  G  PF D+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>88</Hit_num>
  <Hit_id>YIL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:287790:288908:-1 gene:YIL035C transcript:YIL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA1 description:Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000001297]</Hit_def>
  <Hit_accession>YIL035C</Hit_accession>
  <Hit_len>372</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>1.52447e-06</Hsp_evalue>
      <Hsp_query-from>136</Hsp_query-from>
      <Hsp_query-to>426</Hsp_query-to>
      <Hsp_hit-from>178</Hsp_hit-from>
      <Hsp_hit-to>272</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>98</Hsp_align-len>
      <Hsp_qseq>QILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRK-DPYGKPVDMWACGVILYILLVGYPPFW</Hsp_qseq>
      <Hsp_hseq>ELLKALDYCHSMGIMHRDVKPHNVMIDHKNK--KLRLIDWGLA-EFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFF</Hsp_hseq>
      <Hsp_midline>++L+++ +CH  GI+HRD+KP N+++  K K   ++L D+GLA E       +     +  +  PE+L     Y   +D+W+ G +L  ++    PF+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>89</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>1.98607e-06</Hsp_evalue>
      <Hsp_query-from>94</Hsp_query-from>
      <Hsp_query-to>432</Hsp_query-to>
      <Hsp_hit-from>132</Hsp_hit-from>
      <Hsp_hit-to>243</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>115</Hsp_align-len>
      <Hsp_qseq>REYYSEADASHCIQQILESVHHCHQHG-IVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPE-VLRKDPYGKPVDMWACGVILYILLVGYPPFWDE</Hsp_qseq>
      <Hsp_hseq>RTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDP--ETWSLKLCDFGSAKQLKPTEPN-VSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGE</Hsp_hseq>
      <Hsp_midline>R   S  +  + + Q+ +S+++ H    + HRD+KP+NLL+    +  ++KL DFG A +++  +     +  +  Y +PE +     Y   +D+W+ G ++  LL+G P F  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>90</Hit_num>
  <Hit_id>YOR061W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:441534:442553:1 gene:YOR061W transcript:YOR061W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA2 description:Alpha&apos; catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000005587]</Hit_def>
  <Hit_accession>YOR061W</Hit_accession>
  <Hit_len>339</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>2.75593e-06</Hsp_evalue>
      <Hsp_query-from>115</Hsp_query-from>
      <Hsp_query-to>540</Hsp_query-to>
      <Hsp_hit-from>143</Hsp_hit-from>
      <Hsp_hit-to>272</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>143</Hsp_align-len>
      <Hsp_qseq>DASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRK-DPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDQRSTVASCMHRQETVECLRKF</Hsp_qseq>
      <Hsp_hseq>DIQYYFTQLLIALDYCHSMGIMHRDVKPQNVMIDPTER--KLRLIDWGLA-EFYHPGVDYNVRVASRYHKGPELLVNLNQYDYSLDLWSVGCMLAAIVFKKEPFFKGSSNP----------DQLVKIATVLGTKELLGYLGKY</Hsp_hseq>
      <Hsp_midline>D  +   Q+L ++ +CH  GI+HRD+KP+N+++    +   ++L D+GLA E       +     +  +  PE+L   + Y   +D+W+ G +L  ++    PF+    +           DQ   +A+ +  +E +  L K+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>91</Hit_num>
  <Hit_id>YJL057C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:328118:330121:-1 gene:YJL057C transcript:YJL057C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IKS1 description:Protein kinase of unknown cellular role; putative serine/threonine kinase; expression is induced during mild heat stress; deletion mutants are hypersensitive to copper sulphate and resistant to sorbate; interacts with an N-terminal fragment of Sst2p [Source:SGD;Acc:S000003593]</Hit_def>
  <Hit_accession>YJL057C</Hit_accession>
  <Hit_len>667</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>6.22021e-06</Hsp_evalue>
      <Hsp_query-from>130</Hsp_query-from>
      <Hsp_query-to>492</Hsp_query-to>
      <Hsp_hit-from>331</Hsp_hit-from>
      <Hsp_hit-to>486</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>43</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>IQQILESVHHCHQHGIVHRDLKPENLLLASKMKG------------------AAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPV--------------------DMWACGVILYILLVGYPPFWDE-DQHKLYQQIKAGAYDQRSTV</Hsp_qseq>
      <Hsp_hseq>IRDIARGLHELHSIGLIHRDLKPSNCLLLTPFKSDNENDNVYDREHNSDEFFPSIVIGDLGES-QLEGESRLGTGCTGTLEFTAPDLIIQ---GRPVSSSTLPSRSSHTYNEYTFASDMYSLGMICYFIVFGELPFEPQLDIVDLKVRIKNFRFDTEGMI</Hsp_hseq>
      <Hsp_midline>I+ I   +H  H  G++HRDLKP N LL +  K                    ++ + D G + +++G+ +   G  GT  + +P+++ +   G+PV                    DM++ G+I Y ++ G  PF  + D   L  +IK   +D    +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>102</Statistics_hsp-len>
      <Statistics_eff-space>2780915947</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0043394-RA transcript Note:&quot;Similar to camk2d1 Calcium/calmodulin-dependent protein kinase type II delta 1 chain (Danio rerio)&quot; offset:305 AED:0.55 eAED:0.55 QI:305|0|0|0.25|0|0|4|0|107</Iteration_query-def>
  <Iteration_query-len>629</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>85</Statistics_hsp-len>
      <Statistics_eff-space>291780308</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056813-RA transcript Note:&quot;Similar to lrit2 Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 2 (Danio rerio)&quot; offset:0 AED:0.05 eAED:0.05 QI:0|0|0|1|1|1|2|0|515</Iteration_query-def>
  <Iteration_query-len>1548</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>967927474</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056814-RA transcript Note:&quot;Similar to CDHR1 Cadherin-related family member 1 (Gallus gallus)&quot; offset:0 AED:0.14 eAED:0.16 QI:0|0.27|0.25|0.91|0.72|0.75|12|537|531</Iteration_query-def>
  <Iteration_query-len>2133</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1396154338</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056818-RA transcript Note:&quot;Protein of unknown function&quot; offset:966 AED:0.25 eAED:0.25 QI:966|0.8|0.81|1|0.5|0.36|11|1507|142</Iteration_query-def>
  <Iteration_query-len>2902</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>1962258956</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056821-RA transcript Note:&quot;Similar to TNIP1 TNFAIP3-interacting protein 1 (Homo sapiens)&quot; offset:158 AED:0.05 eAED:0.05 QI:158|0.83|1|1|0.83|0.85|7|2387|190</Iteration_query-def>
  <Iteration_query-len>3118</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2116568913</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0063397-RA transcript Note:&quot;Similar to Usp36 Ubiquitin carboxyl-terminal hydrolase 36 (Mus musculus)&quot; offset:0 AED:0.22 eAED:0.22 QI:0|0.78|0.86|1|0.78|0.86|15|1813|646</Iteration_query-def>
  <Iteration_query-len>3754</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YMR223W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:716715:718130:1 gene:YMR223W transcript:YMR223W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBP8 description:Ubiquitin-specific protease component of the SAGA acetylation complex; required for SAGA (Spt-Ada-Gcn5-Acetyltransferase)-mediated deubiquitination of histone H2B [Source:SGD;Acc:S000004836]</Hit_def>
  <Hit_accession>YMR223W</Hit_accession>
  <Hit_len>471</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>137.117</Hsp_bit-score>
      <Hsp_score>344</Hsp_score>
      <Hsp_evalue>1.43747e-34</Hsp_evalue>
      <Hsp_query-from>826</Hsp_query-from>
      <Hsp_query-to>1653</Hsp_query-to>
      <Hsp_hit-from>137</Hsp_hit-from>
      <Hsp_hit-to>465</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>95</Hsp_identity>
      <Hsp_positive>161</Hsp_positive>
      <Hsp_gaps>55</Hsp_gaps>
      <Hsp_align-len>330</Hsp_align-len>
      <Hsp_qseq>AGLRNLGNTCFLNATLQCLAYTPPLVNYLLLQEHCSTCE-RS-DFCLMCVMERHVVSTFN--NSQRVLTPSGITKNIT----------RIAKHLRIGRQEDAHEFLRYVVDAMQASC---LHGHSELDRYT--EATTLIYQIFGGYLRSRVAC---------------VISFIVVNSSDLVEAFGEFFNEEILDE--YTCARCCCKGEATKTMALHRLPNVLTVSIKRYNLYGN---------ITYPEHLDMQPFTSTSQGEP---------AIYSLYSVLVHKGADSNSGHYYCYNKISDGQWCRMNDSIVRHVDTKAVMNEQAYMLFY</Hsp_qseq>
      <Hsp_hseq>SGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDLSLDIKDKKKLYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEHLLNGSNRKLDDFIEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSHKGT-VNEGHYIAFCKISGGQWFKFNDSMVSSISQEEVLKEQAYLLFY</Hsp_hseq>
      <Hsp_midline>+GL N+G+TCF+++ LQCL + P  + + + Q H + C+ RS D C  C +++ V   +   N+++  + S  T   T          +I ++L    Q+DAHEF +++++ +  S    L    E+ R    +   +++ +F G L S + C                +S  + +   L E    F  +E L +  Y C  C    +A K + +H+LP+VL + +KR+    N         I +P +L+M+ + ST + +           IY L  ++ HKG   N GHY  + KIS GQW + NDS+V  +  + V+ EQAY+LFY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YER144C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:457806:460223:-1 gene:YER144C transcript:YER144C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBP5 description:Putative ubiquitin-specific protease; concentrates at the bud neck; UBP5 has a paralog, DOA4, that arose from the whole genome duplication [Source:SGD;Acc:S000000946]</Hit_def>
  <Hit_accession>YER144C</Hit_accession>
  <Hit_len>805</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.6481</Hsp_bit-score>
      <Hsp_score>200</Hsp_score>
      <Hsp_evalue>4.23847e-16</Hsp_evalue>
      <Hsp_query-from>811</Hsp_query-from>
      <Hsp_query-to>1659</Hsp_query-to>
      <Hsp_hit-from>441</Hsp_hit-from>
      <Hsp_hit-to>803</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>89</Hsp_identity>
      <Hsp_positive>144</Hsp_positive>
      <Hsp_gaps>84</Hsp_gaps>
      <Hsp_align-len>365</Hsp_align-len>
      <Hsp_qseq>DVGKGAGLRNLGNTCFLNATLQCLAYTPPLVNYLLLQEHCSTCE-RSDFCLMCVMERHVVSTFNNSQR--VLTPSGI------TKNITRIAKHLR----IGRQEDAHEFLRYVVDAMQASCLHGHS---------ELDRYTEATTL------------------IYQIFGGYLRSRVACVI---------SFIV-------VNSSDLVEAFGEFFNEEIL---DEYTCARCCCKGEATKTMALHRLPNVLTVSIKRYNLYGN-----ITYPEHLDMQPFTSTSQGEPAI---------------YSLYSVLVHKGADSNSGHY--YCYNKISDGQWCRMNDSIVRHVD-TKAVMNEQAYMLFYIR</Hsp_qseq>
      <Hsp_hseq>DLDLIVGLENIGNCCYMNCILQCLVGTHDLVRMFLDNTYLNFINFDSSRGSKGLLAKNFAILVNNMHRHGAFTPPNVRTIPVQTIQFKKICGHINPMYSDSMQQDCQEFCQFLLDGLHEDLNQNGSKKHLKQLSDEEERMREKMSIRKASALEWERFLLTDFSAIIDLFQGQYASRLQCQVCEHTSTTYQTFSVLSVPVPRVKTCNILDCFREFTKCERLGVDEQWSCPKCLKKQPSTKQLKITRLPKKLIINLKRFDNQMNKNNVFVQYPYSLDLTPYWARDFNHEAIVNEDIPTRGQVPPFRYRLYGVACHSGS-LYGGHYTSYVYKGPKKG-WYFFDDSLYRPITFSTEFITPSAYVLFYER</Hsp_hseq>
      <Hsp_midline>D+    GL N+GN C++N  LQCL  T  LV   L   + +     S      ++ ++     NN  R    TP  +      T    +I  H+        Q+D  EF ++++D +        S         E +R  E  ++                  I  +F G   SR+ C +         +F V       V + ++++ F EF   E L   ++++C +C  K  +TK + + RLP  L +++KR++   N     + YP  LD+ P+ +      AI               Y LY V  H G+    GHY  Y Y     G W   +DS+ R +  +   +   AY+LFY R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YDR069C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:584939:587719:-1 gene:YDR069C transcript:YDR069C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DOA4 description:Ubiquitin hydrolase; deubiquitinates intralumenal vesicle (ILVs) cargo proteins; required for recycling ubiquitin from proteasome-bound ubiquitinated intermediates, acts at the late endosome/prevacuolar compartment to recover ubiquitin from ubiquitinated membrane proteins destined for the vacuole; DOA4 has a paralog, UBP5, that arose from the whole genome duplication [Source:SGD;Acc:S000002476]</Hit_def>
  <Hit_accession>YDR069C</Hit_accession>
  <Hit_len>926</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.8702</Hsp_bit-score>
      <Hsp_score>185</Hsp_score>
      <Hsp_evalue>3.16161e-14</Hsp_evalue>
      <Hsp_query-from>811</Hsp_query-from>
      <Hsp_query-to>1659</Hsp_query-to>
      <Hsp_hit-from>557</Hsp_hit-from>
      <Hsp_hit-to>922</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>87</Hsp_identity>
      <Hsp_positive>143</Hsp_positive>
      <Hsp_gaps>87</Hsp_gaps>
      <Hsp_align-len>368</Hsp_align-len>
      <Hsp_qseq>DVGKGAGLRNLGNTCFLNATLQCLAYTPPLVNYLL---LQEHCSTCER--SDFCLMCVMERHVVSTF----NNSQRV-LTPSGITKNITRIAKHLRIGRQEDAHEFLRYVVDAMQASC--------------------------LHGHSELDRY-TEATTLIYQIFGGYLRSRVACVI---------SFIVV----------NSSDLVEAFGEFF---NEEILDEYTCARCCCKGEATKTMALHRLPNVLTVSIKRYNLYGN-----ITYPEHLDMQPFTSTS------------------QGEPAIYSLYSVLVHKGADSNSGHYYCYNK--ISDGQWCRMNDSIVRHVDTKA-VMNEQAYMLFYIR</Hsp_qseq>
      <Hsp_hseq>DLDFAVGLENLGNSCYMNCIIQCILGTHELTQIFLDDSYAKHININSKLGSKGILAKYFARLVHMMYKEQVDGSKKISISPIKFKLACGSVNSLFKTASQQDCQEFCQFLLDGLHEDLNQCGSNPPLKELSQEAEARREKLSLRIASSIEWERFLTTDFSVIVDLFQGQYASRLKCKVCSHTSTTYQPFTVLSIPIPKKNSRNNITIEDCFREFTKCENLEVDEQWLCPHCEKRQPSTKQLTITRLPRNLIVHLKRFDNLLNKNNDFVIYPFLLDLTPFWANDFDGVFPPGVNDDELPIRGQIPPFKYELYGVACHFGT-LYGGHYTAYVKKGLKKG-WLYFDDTKYKPVKNKADAINSNAYVLFYHR</Hsp_hseq>
      <Hsp_midline>D+    GL NLGN+C++N  +QC+  T  L    L     +H +   +  S   L     R V   +    + S+++ ++P         +    +   Q+D  EF ++++D +                              +    E +R+ T   ++I  +F G   SR+ C +          F V+          N+  + + F EF    N E+ +++ C  C  +  +TK + + RLP  L V +KR++   N     + YP  LD+ PF +                    Q  P  Y LY V  H G     GHY  Y K  +  G W   +D+  + V  KA  +N  AY+LFY R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YNL186W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:289498:291876:1 gene:YNL186W transcript:YNL186W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBP10 description:Ubiquitin-specific protease, deubiquitinates Ub-protein moieties; interacts with proteins that function in rRNA production and ribosome biogenesis via its intrinsically disordered regions; stabilizes Rpa190p by deubiquitination; controls PCNA deubiquitylation; may regulate silencing by acting on Sir4p; involved in posttranscriptionally regulating Gap1p, possibly other transporters; localized to the nucleolus; null mutant phenotypes are functionally complemented by human USP36 [Source:SGD;Acc:S000005130]</Hit_def>
  <Hit_accession>YNL186W</Hit_accession>
  <Hit_len>792</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.559</Hsp_bit-score>
      <Hsp_score>179</Hsp_score>
      <Hsp_evalue>1.21848e-13</Hsp_evalue>
      <Hsp_query-from>1267</Hsp_query-from>
      <Hsp_query-to>1659</Hsp_query-to>
      <Hsp_hit-from>588</Hsp_hit-from>
      <Hsp_hit-to>732</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>146</Hsp_align-len>
      <Hsp_qseq>EAFGEFFNEEILD------EYTCARCCCKGEATKTMALHRLPNVLTVSIKRYNLYGN--------ITYPEHLDMQPFTSTSQGEPAIYSLYSVLVHKGADSNSGHYYCYNKISDGQWCRMNDSIVRHVDTKAVMNE-QAYMLFYIR</Hsp_qseq>
      <Hsp_hseq>KSIKDFFNPELIKVDKEQKGYVCEKCHKTTNAVKHSSILRAPETLLVHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCE-SKELPVKYQLLSVVVHEGRSLSSGHYIAHCKQPDGSWATYDDEYINIISERDVLKEPNAYYLLYTR</Hsp_hseq>
      <Hsp_midline>++  +FFN E++        Y C +C     A K  ++ R P  L V +K++   G         ++YP  LD+  +   S+  P  Y L SV+VH+G   +SGHY  + K  DG W   +D  +  +  + V+ E  AY L Y R</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>1.52077e-07</Hsp_evalue>
      <Hsp_query-from>829</Hsp_query-from>
      <Hsp_query-to>1227</Hsp_query-to>
      <Hsp_hit-from>363</Hsp_hit-from>
      <Hsp_hit-to>500</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>144</Hsp_align-len>
      <Hsp_qseq>GLRNLGNTCFLNATLQCLAYTPPLVNYL---LLQEHCSTCERS--DFCLMCVMERHVVSTFNN-----SQRVLTPSGITKNITRIAKHLRIGRQEDAHEFLRYVVDAMQASCL-HGHSELDRYTEATTLIYQIFGGYLRSRVAC</Hsp_qseq>
      <Hsp_hseq>GLLNHGVTCYTNAAVQAMLHIPSIQHYLFDILMGKYDSTISKNSVSYTLAETSKKMWLPVSKNPRKNVSASYINPKHLISRLDDINCMMSEWQQEDSHEYFMSLMSRLQEDSVPKGHKLIE------SIIYDIFGGLLKQIVTC</Hsp_hseq>
      <Hsp_midline>GL N G TC+ NA +Q + + P + +YL   L+ ++ ST  ++   + L    ++  +    N     S   + P  +   +  I   +   +QED+HE+   ++  +Q   +  GH  ++      ++IY IFGG L+  V C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YBL067C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:93639:95882:-1 gene:YBL067C transcript:YBL067C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBP13 description:Ubiquitin-specific protease that cleaves Ub-protein fusions; UBP13 has a paralog, UBP9, that arose from the whole genome duplication [Source:SGD;Acc:S000000163]</Hit_def>
  <Hit_accession>YBL067C</Hit_accession>
  <Hit_len>747</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>5.31014e-13</Hsp_evalue>
      <Hsp_query-from>1012</Hsp_query-from>
      <Hsp_query-to>1653</Hsp_query-to>
      <Hsp_hit-from>409</Hsp_hit-from>
      <Hsp_hit-to>665</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>53</Hsp_gaps>
      <Hsp_align-len>262</Hsp_align-len>
      <Hsp_qseq>VLTPSGITKNITRIAKHLRIGRQEDAHEFLRYVVDAMQ-----------ASCLHGHSELDRYTEATTLIYQIFGGYLRSRVACV------------ISFIVV----NSSDLVEAFGEFFNEEILD---EYTCARCCCKGEATKTMALHRLPNVLTVSIKRY----------NLYGNITYPEHLDMQPFTSTSQGEPAIYSLYSVLVHKGADSNSGHYYCYNKISDGQWCRMNDSIVRHVDTKAVMN--------EQAYMLFY</Hsp_qseq>
      <Hsp_hseq>VVSPSSFVDVLKRENVLFNTTMHQDAHEFFNFLLNELSEYIERENKKIAASDINSDSEP---SKSKNFISDLFQGTLTNQIKCLTCDNITSRDEPFLDFPIEVQGDEETDIQEILKSYHQREMLNGSNKFYCDECCGLQEAERLVGLKQLPDTLTLHLKRFKYSEKQNCNIKLFNNIHYP--LTLNVCSSINSKVCQKYELAGIVVHMGGGPQHGHYVSLCKHEKFGWLLFDDETVEAVKEETVLEFTGESPNMATAYVLFY</Hsp_hseq>
      <Hsp_midline>V++PS     + R          +DAHEF  ++++ +            AS ++  SE    +++   I  +F G L +++ C+            + F +       +D+ E    +   E+L+   ++ C  CC   EA + + L +LP+ LT+ +KR+           L+ NI YP  L +   +S +      Y L  ++VH G     GHY    K     W   +D  V  V  + V+           AY+LFY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YMR304W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:874987:878679:1 gene:YMR304W transcript:YMR304W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBP15 description:Ubiquitin-specific protease involved in protein deubiquitination; forms a complex with AAA peroxins Pex1p and Pex6p; deubiquitinates mono- and polyubiquitinated forms of Pex5p; deubiquitinates Clb5p, counteracting APC activity, and facilitating both Clb5p accumulation and S phase entry; physically interacts with anaphase-promoting complex/cyclosome (APC/C) activator, Cdh1p; catalytic activity regulated by an N-terminal TRAF-like domain and and C-terminal sequences [Source:SGD;Acc:S000004920]</Hit_def>
  <Hit_accession>YMR304W</Hit_accession>
  <Hit_len>1230</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.8626</Hsp_bit-score>
      <Hsp_score>172</Hsp_score>
      <Hsp_evalue>1.01204e-12</Hsp_evalue>
      <Hsp_query-from>826</Hsp_query-from>
      <Hsp_query-to>1740</Hsp_query-to>
      <Hsp_hit-from>205</Hsp_hit-from>
      <Hsp_hit-to>564</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>92</Hsp_identity>
      <Hsp_positive>139</Hsp_positive>
      <Hsp_gaps>91</Hsp_gaps>
      <Hsp_align-len>378</Hsp_align-len>
      <Hsp_qseq>AGLRNLGNTCFLNATLQCLAYTPPL--VNYLLLQEHCSTCERSDFCLMCVMERHVVSTFNNSQRVLTPSGITKNITRIAKHLRIGRQEDAHEFLRYVVDAMQASCLHGHSELDRYTEATTLIYQIFGGYLRSRVACV--------------ISFIVVNSSDLVEAFGEFFNEEIL--DEYTCARCCCKGEATKTMALHRLPNVLTVSIKRYNLYGNIT----------YPEHLDMQPF-----------TSTSQGEPAIYSLYSVLVHKGADSNSGHYYCYNK--ISDGQWCRMNDSIVRHVDTKAVMNEQ-----------------------------AYMLFYIR---SPELNAPPADSYRPLEHVKAKSRLCIK</Hsp_qseq>
      <Hsp_hseq>VGFRNQGATCYLNSLLQSYFFTKYFRKLVYEIPTEHESPNNSVPLALQRAFYQLQVSDIPLDTLELTRSFGWDTAESFTQH-------DVQELNRILMDRLENNM--------KGTPVEGKLNEIFVGKMKSYIKCINVDYESARVEDFWDLQLNVKNFKNLQESFDNYIEMELMNGENQYAAQDYGLQDAQKGVIFESFPPVLHLQLKRFEYDFNYDQMVKVNDKYEFPETIDLSPFVDKDVLKKTLDSENKDKNPYVYNLHGVLVHSG-DISTGHYYTLIKPGVED-QWYRFDDERVWRVTKKQVFQENFGCDRLPDEKVRTMTRGEYQNYIIQRHTSAYMLVYIRQEQEEDLLRPVLESDVP-KHVITRVREEIK</Hsp_hseq>
      <Hsp_midline> G RN G TC+LN+ LQ   +T     + Y +  EH S        L     +  VS        LT S          +H       D  E  R ++D ++ +         + T     + +IF G ++S + C+              +   V N  +L E+F  +   E++  +    A+     +A K +     P VL + +KR+    N            +PE +D+ PF           +      P +Y+L+ VLVH G D ++GHYY   K  + D QW R +D  V  V  K V  E                              AYML YIR     +L  P  +S  P +HV  + R  IK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YER098W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:355466:357730:1 gene:YER098W transcript:YER098W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBP9 description:Ubiquitin-specific protease that cleaves ubiquitin-protein fusions; UBP9 has a paralog, UBP13, that arose from the whole genome duplication [Source:SGD;Acc:S000000900]</Hit_def>
  <Hit_accession>YER098W</Hit_accession>
  <Hit_len>754</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>1.59215e-12</Hsp_evalue>
      <Hsp_query-from>1012</Hsp_query-from>
      <Hsp_query-to>1653</Hsp_query-to>
      <Hsp_hit-from>411</Hsp_hit-from>
      <Hsp_hit-to>664</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>257</Hsp_align-len>
      <Hsp_qseq>VLTPSGITKNITRIAKHLRIGRQEDAHEFLRYVVDAMQASCLHGHSELDRYTEATT------LIYQIFGGYLRSRVACV----------------ISFIVVNSSDLVEAFGEFFNEEILD---EYTCARCCCKGEATKTMALHRLPNVLTVSIKRYN----------LYGNITYPEHLDMQPFTSTSQGEPAIYSLYSVLVHKGADSNSGHYYCYNKISDGQWCRMNDSIVRHVDTKAVM--------NEQAYMLFY</Hsp_qseq>
      <Hsp_hseq>IVSPTEFVKILKKENVLFNTMMQQDAHEFLNFLLNDFSEYIQRNNPRM-RFGPQKTDNSNDNFITDLFKGTLTNRIKCLTCDNITSRDEPFLDFPIEVQGDEETDIQKMLKSYHQREMLNGVNKFYCNKCYGLQEAERMVGLKQLPHILSLHLKRFKYSEEQKSNIKLFNKILYPLTLDVSSTFNTSVYKK--YELSGVVIHMGSGPQHGHYVCICRNEKFGWLLYDDETVESIKEETVLQFTGHPGDQTTAYVLFY</Hsp_hseq>
      <Hsp_midline>+++P+   K + +         Q+DAHEFL ++++         +  + R+    T       I  +F G L +R+ C+                I       +D+ +    +   E+L+   ++ C +C    EA + + L +LP++L++ +KR+           L+  I YP  LD+    +TS  +   Y L  V++H G+    GHY C  +     W   +D  V  +  + V+           AY+LFY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YJL197W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:63805:67569:1 gene:YJL197W transcript:YJL197W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBP12 description:Ubiquitin-specific protease; cleaves ubiquitin from ubiquitinated proteins; present in the nucleus and cytoplasm [Source:SGD;Acc:S000003733]</Hit_def>
  <Hit_accession>YJL197W</Hit_accession>
  <Hit_len>1254</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>2.95602e-06</Hsp_evalue>
      <Hsp_query-from>1282</Hsp_query-from>
      <Hsp_query-to>1659</Hsp_query-to>
      <Hsp_hit-from>971</Hsp_hit-from>
      <Hsp_hit-to>1109</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>141</Hsp_align-len>
      <Hsp_qseq>FFNEEIL---DEYTCARCCCKGEATKTMALHRLPNVLTVSIKRY--------NLYGNITYP-EHLDMQPFTSTSQGEP--AIYSLYSVLVHKGADSNSGHYYCYNK-ISDGQWCRMNDSIVRHVDTKAVMNEQAYMLFYIR</Hsp_qseq>
      <Hsp_hseq>FSKPEILGLTDSWYCPTCKEHRQATKQIQLWNTPDILLIHLKRFESQRSFSDKIDATVNFPITDLDLSRYV-VYKDDPRGLIYDLYAVDNHYGG-LGGGHYTAYVKNFADNKWYYFDDSRVTETAPENSIAGSAYLLFYIR</Hsp_hseq>
      <Hsp_midline>F   EIL   D + C  C    +ATK + L   P++L + +KR+         +   + +P   LD+  +    + +P   IY LY+V  H G     GHY  Y K  +D +W   +DS V     +  +   AY+LFYIR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2584587050</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0038285-RA transcript Note:&quot;Similar to prps2 Ribose-phosphate pyrophosphokinase 2 (Xenopus tropicalis)&quot; offset:0 AED:0.50 eAED:0.59 QI:0|0|0|0.66|0|0|3|0|111</Iteration_query-def>
  <Iteration_query-len>336</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YBL068W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:92414:93394:1 gene:YBL068W transcript:YBL068W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRS4 description:5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP; which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes; PRS4 has a paralog, PRS2, that arose from the whole genome duplication; a missense mutation in the conserved residue R196 of its human homolog PRPS1 is pathogenic [Source:SGD;Acc:S000000164]</Hit_def>
  <Hit_accession>YBL068W</Hit_accession>
  <Hit_len>326</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>131.339</Hsp_bit-score>
      <Hsp_score>329</Hsp_score>
      <Hsp_evalue>3.47326e-39</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>330</Hsp_query-to>
      <Hsp_hit-from>80</Hsp_hit-from>
      <Hsp_hit-to>245</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>56</Hsp_gaps>
      <Hsp_align-len>166</Hsp_align-len>
      <Hsp_qseq>MEMLIMINACKIASSSRVTAVIPCFPYARQDKKDKVR------------QRGGDD-------------GFFDIPVDNL-------------------------------VTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRIAILVDDMADTCGTICHAAD</Hsp_qseq>
      <Hsp_hseq>MELLILIHACKIASARKITTVIPNFPYARQDKKDKSRAPITAKLVANLLQTAGADHVITMDLHASQIQGFFHIPVDNLYAEPSVLNYIRTKTDFDNAILVSPDAGGAKRVAALADKLDLNFALIHKERQKANEVSKMVLVGDVTNKSCLLVDDMADTCGTLVKACD</Hsp_hseq>
      <Hsp_midline>ME+LI+I+ACKIAS+ ++T VIP FPYARQDKKDK R            Q  G D             GFF IPVDNL                               V ++AD+L+++FALIHKER+KANEV +MVLVGDV ++  +LVDDMADTCGT+  A D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YHL011C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:80654:81616:-1 gene:YHL011C transcript:YHL011C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRS3 description:5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase; synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes [Source:SGD;Acc:S000001003]</Hit_def>
  <Hit_accession>YHL011C</Hit_accession>
  <Hit_len>320</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>131.339</Hsp_bit-score>
      <Hsp_score>329</Hsp_score>
      <Hsp_evalue>3.83353e-39</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>330</Hsp_query-to>
      <Hsp_hit-from>71</Hsp_hit-from>
      <Hsp_hit-to>236</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>56</Hsp_gaps>
      <Hsp_align-len>166</Hsp_align-len>
      <Hsp_qseq>MEMLIMINACKIASSSRVTAVIPCFPYARQDKKDKVR-------------QRGGD------------DGFFDIPVDNL-------------------------------VTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRIAILVDDMADTCGTICHAAD</Hsp_qseq>
      <Hsp_hseq>LELLIMINASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENVNYMDSIIISPDAGGAKRAATLADRLDLNFALIHKERARANEVSRMVLVGDVTDKICIIVDDMADTCGTLAKAAE</Hsp_hseq>
      <Hsp_midline>+E+LIMINA K AS+ R+TA+IP FPYARQD+KDK R               G D             GFFD+PVDNL                                 ++ADRL+++FALIHKER +ANEV RMVLVGDV D+I I+VDDMADTCGT+  AA+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YER099C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:358105:359061:-1 gene:YER099C transcript:YER099C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRS2 description:5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP; which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes; PRS2 has a paralog, PRS4, that arose from the whole genome duplication [Source:SGD;Acc:S000000901]</Hit_def>
  <Hit_accession>YER099C</Hit_accession>
  <Hit_len>318</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>127.872</Hsp_bit-score>
      <Hsp_score>320</Hsp_score>
      <Hsp_evalue>6.80376e-38</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>330</Hsp_query-to>
      <Hsp_hit-from>72</Hsp_hit-from>
      <Hsp_hit-to>237</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>56</Hsp_gaps>
      <Hsp_align-len>166</Hsp_align-len>
      <Hsp_qseq>MEMLIMINACKIASSSRVTAVIPCFPYARQDKKDKVR------------QRGGDD-------------GFFDIPVDNL-------------------------------VTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRIAILVDDMADTCGTICHAAD</Hsp_qseq>
      <Hsp_hseq>MELLILIHACKTASVRRITAVIPNFPYARQDKKDKSRAPITAKLIANLLETAGCDHVITMDLHASQIQGFFHIPVDNLYGEPSVLNYIRTKTDFNNAILVSPDAGGAKRVASLADKLDMNFALIHKERQKANEVSRMLLVGDVAGKSCLLIDDMADTCGTLVKACD</Hsp_hseq>
      <Hsp_midline>ME+LI+I+ACK AS  R+TAVIP FPYARQDKKDK R            +  G D             GFF IPVDNL                               V S+AD+L+++FALIHKER+KANEV RM+LVGDV  +  +L+DDMADTCGT+  A D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YKL181W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:107316:108599:1 gene:YKL181W transcript:YKL181W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRS1 description:5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase; synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; plays a key role in cell wall integrity (CWI) pathway; one of five related enzymes, which are active as heteromultimeric complexes; missense mutations in human homolog PRPS1 are associated with neuropathic Arts syndrome and Charcot-Marie Tooth (CMTX5) disease [Source:SGD;Acc:S000001664]</Hit_def>
  <Hit_accession>YKL181W</Hit_accession>
  <Hit_len>427</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>2.53998e-11</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>234</Hsp_query-to>
      <Hsp_hit-from>68</Hsp_hit-from>
      <Hsp_hit-to>202</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>57</Hsp_gaps>
      <Hsp_align-len>135</Hsp_align-len>
      <Hsp_qseq>MEMLIMINACKIASSSRVTAVIPCFPYARQDKKDKVR-------------QRGGD------------DGFFDIPVDNL--------------------------------VTSIADRLNVDFALIHKERKKANEV</Hsp_qseq>
      <Hsp_hseq>MELLILVSACRGGSARKITAVIPQFPYSKQCKMKRHRGAITARMLANLLVMAGADHVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRENVEDYEDAVVVSKNPGGTKRVTALADSLKINFAMIHTDRRRSKDL</Hsp_hseq>
      <Hsp_midline>ME+LI+++AC+  S+ ++TAVIP FPY++Q K  + R               G D             GFF  PVDNL                                VT++AD L ++FA+IH +R+++ ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YOL061W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:212244:213734:1 gene:YOL061W transcript:YOL061W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRS5 description:5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase; synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes; forms cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000005422]</Hit_def>
  <Hit_accession>YOL061W</Hit_accession>
  <Hit_len>496</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>43.8986</Hsp_bit-score>
      <Hsp_score>102</Hsp_score>
      <Hsp_evalue>1.08721e-06</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>90</Hsp_query-to>
      <Hsp_hit-from>70</Hsp_hit-from>
      <Hsp_hit-to>99</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>19</Hsp_identity>
      <Hsp_positive>26</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>30</Hsp_align-len>
      <Hsp_qseq>MEMLIMINACKIASSSRVTAVIPCFPYARQ</Hsp_qseq>
      <Hsp_hseq>MQLLILISACKSASASRVTAVMPYLCYSRQ</Hsp_hseq>
      <Hsp_midline>M++LI+I+ACK AS+SRVTAV+P   Y+RQ</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>77</Statistics_hsp-len>
      <Statistics_eff-space>84205345</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0063928-RA transcript Note:&quot;Similar to LGALS3 Galectin-3 (Canis lupus familiaris)&quot; offset:0 AED:0.43 eAED:0.49 QI:0|0|0|0.33|1|1|3|0|786</Iteration_query-def>
  <Iteration_query-len>2361</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1568968230</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0063910-RA transcript Note:&quot;Similar to Tnik Traf2 and NCK-interacting protein kinase (Mus musculus)&quot; offset:0 AED:0.62 eAED:0.65 QI:0|0|0|0.66|1|1|3|0|113</Iteration_query-def>
  <Iteration_query-len>342</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>77</Statistics_hsp-len>
      <Statistics_eff-space>89017079</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0048914-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0|0|2|0|74</Iteration_query-def>
  <Iteration_query-len>225</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>47</Statistics_hsp-len>
      <Statistics_eff-space>72908276</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0062583-RA transcript Note:&quot;Similar to DYRK4 Dual specificity tyrosine-phosphorylation-regulated kinase 4 (Homo sapiens)&quot; offset:0 AED:0.58 eAED:0.59 QI:0|0.2|0.36|0.63|1|1|11|0|315</Iteration_query-def>
  <Iteration_query-len>948</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>8.10532e-13</Hsp_evalue>
      <Hsp_query-from>85</Hsp_query-from>
      <Hsp_query-to>594</Hsp_query-to>
      <Hsp_hit-from>353</Hsp_hit-from>
      <Hsp_hit-to>550</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>198</Hsp_align-len>
      <Hsp_qseq>WFFTVDKVRKEQLNYRYEVQKMIGEGGQGLVLQCRDHKTKTLVAVKML---SLPLWTELEVAK--ELQGRASD--ERYGVIRVLDTFEFRCHNCLVVELLKKSLYDVMSKGSIGRIYVRRLREYTRAILNFLLYAKGRGIIHGDIKP---ILGMPPK---KMVD------EAPNKTTYFD------PE---GLPYNLS</Hsp_qseq>
      <Hsp_hseq>YILYVNDVLGVEQNRKYLVLDILGQGTFGQVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKNHLCLVFELLSNNLYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPELKIIDFGSSCEEARTVYTYIQSRFYRAPEIILGIPYSTS</Hsp_hseq>
      <Hsp_midline>+   V+ V   + N +Y V  ++G+G  G V++C++  TK ++AVK++   +  L   +  AK  EL  +  D   ++  +R+ D+F  + H CLV ELL  +LY+++ +     + ++ +R +T  IL+ L   K   +IH D+KP   +L  P K   K++D      EA    TY        PE   G+PY+ S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YLL019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:105686:107899:-1 gene:YLL019C transcript:YLL019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KNS1 description:Protein kinase involved in negative regulation of PolIII transcription; effector kinase of the TOR signaling pathway and phosphorylates Rpc53p to regulate ribosome and tRNA biosynthesis; member of the LAMMER family of protein kinases, which are serine/threonine kinases also capable of phosphorylating tyrosine residues; capable of autophosphorylation [Source:SGD;Acc:S000003942]</Hit_def>
  <Hit_accession>YLL019C</Hit_accession>
  <Hit_len>737</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>2.53542e-12</Hsp_evalue>
      <Hsp_query-from>130</Hsp_query-from>
      <Hsp_query-to>672</Hsp_query-to>
      <Hsp_hit-from>312</Hsp_hit-from>
      <Hsp_hit-to>493</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>190</Hsp_align-len>
      <Hsp_qseq>RYEVQKMIGEGGQGLVLQCRDHKTK-TLVAVKMLSL------PLWTELEVAKELQGRASDERYGVIRVLDTFEFRCHNCLVVELLKKSLYDVMSKGSIGRIYVRRLREYTRAILNFLLYAKGRGIIHGDIKP--ILGMPPKKMVDEAPNKTTYFDPEGLPYNLSKQEPPGSLPLHRALQGHHPQLVDFVS</Hsp_qseq>
      <Hsp_hseq>RFVVKDLLGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDRYREAAKTELRILQTILNNDPQGQFQCLLLRECFDYKNHICLVTDLYGRSIYDFMCSNGIARFPGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENILICDETHIAQKLPLKTV--------QSLSKRRREASKGKRKILKNPEIKIIDFGS</Hsp_hseq>
      <Hsp_midline>R+ V+ ++G+G  G VL+C D+K +   VAVK++           TEL + + +       ++  + + + F+++ H CLV +L  +S+YD M    I R     ++   R ++  + +    GIIH D+KP  IL      +  + P KT          +LSK+    S    + L+    +++DF S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>524335142</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0062589-RA transcript Note:&quot;Similar to CHIT1 Chitotriosidase-1 (Homo sapiens)&quot; offset:0 AED:0.44 eAED:0.47 QI:0|0|0|0.37|1|1|8|0|388</Iteration_query-def>
  <Iteration_query-len>1167</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDR371W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1219413:1220948:1 gene:YDR371W transcript:YDR371W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTS2 description:Putative chitinase; functionally complements A. gossypii cts2 mutant sporulation defect [Source:SGD;Acc:S000002779]</Hit_def>
  <Hit_accession>YDR371W</Hit_accession>
  <Hit_len>511</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>5.0337e-14</Hsp_evalue>
      <Hsp_query-from>136</Hsp_query-from>
      <Hsp_query-to>735</Hsp_query-to>
      <Hsp_hit-from>171</Hsp_hit-from>
      <Hsp_hit-to>447</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>85</Hsp_gaps>
      <Hsp_align-len>281</Hsp_align-len>
      <Hsp_qseq>NPQLKFLLAIGGWRFGVEKFSRMVSCAENRRSFIASAIEFLRQHHFDGIDYDWEYPAQRGS--------------------------------------PATDKHLFTLLIQKEDR------------------KTSHHSPLFASTSINQTDTVESSVQTWLRGGVPPQKLVVGLPTYGRSFTL--------SGASTIVGAPVSGAGLPG-------------PYTKQP--GMLAYYEVPY--AYGYTNRRGQWVGYDDIPSFRQKVCWLKSKGLGGAMMW</Hsp_qseq>
      <Hsp_hseq>DKKFKVIMSIGGWS-DSENFKIIIKDDKLLQNFVDSSVETMFRLGFDGIDLDWEFPGNNESEPRGYLKLVRMLRLKLNSLESQIFGKRTEDHFQLSIAAPAFKDKLFYLPITEIDQYVDYWNMMTYDYYGSWSETTGYHSNLFSETELNGNFAMHYMID---RFGVNSRKLVLGMAAYGRSFHIKDNKFEPFNQNTVLINKIFKGVGKPTKEIDKADGKEGIWPYKNLPKIGTIEQYDPKYVSAYCFDEKNSIFISYDNTKSVKTKAEYVTHNNLGGGFWW</Hsp_hseq>
      <Hsp_midline>+ + K +++IGGW    E F  ++   +  ++F+ S++E + +  FDGID DWE+P    S                                      PA    LF L I + D+                   T +HS LF+ T +N    +   +    R GV  +KLV+G+  YGRSF +        +  + ++     G G P              PY   P  G +  Y+  Y  AY +  +   ++ YD+  S + K  ++    LGG   W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>92</Statistics_hsp-len>
      <Statistics_eff-space>685139499</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0062582-RA transcript Note:&quot;Similar to Dyrk4 Dual specificity tyrosine-phosphorylation-regulated kinase 4 (Mus musculus)&quot; offset:0 AED:0.36 eAED:0.36 QI:0|0.64|0.8|0.8|0.57|0.53|15|1350|343</Iteration_query-def>
  <Iteration_query-len>2382</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YLL019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:105686:107899:-1 gene:YLL019C transcript:YLL019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KNS1 description:Protein kinase involved in negative regulation of PolIII transcription; effector kinase of the TOR signaling pathway and phosphorylates Rpc53p to regulate ribosome and tRNA biosynthesis; member of the LAMMER family of protein kinases, which are serine/threonine kinases also capable of phosphorylating tyrosine residues; capable of autophosphorylation [Source:SGD;Acc:S000003942]</Hit_def>
  <Hit_accession>YLL019C</Hit_accession>
  <Hit_len>737</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>5.86987e-12</Hsp_evalue>
      <Hsp_query-from>334</Hsp_query-from>
      <Hsp_query-to>918</Hsp_query-to>
      <Hsp_hit-from>312</Hsp_hit-from>
      <Hsp_hit-to>499</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>198</Hsp_align-len>
      <Hsp_qseq>RYEVQKMIGEGGQGLVLQCRDHKTK-TLVAVKMLSLPLCSSTAARQRTELEVAKKLQGRASDERYGVIRVLDTFEFRGHNCLVVELLKKSLYDVMSKGSIRRIYVRRLREYTRAILNFLLYAKGRGIIHGDIKP--ILGMPPKKMVDEAPNKTTYFDPEGLPYNLSKQVPPGSLPLHRALQGHHPQLVDFVSRCLQYE</Hsp_qseq>
      <Hsp_hseq>RFVVKDLLGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDRYREAAK--TELRILQTILNNDPQGQFQCLLLRECFDYKNHICLVTDLYGRSIYDFMCSNGIARFPGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENILICDETHIAQKLPLKTV--------QSLSKRRREASKGKRKILKNPEIKIIDFGSAIFHYE</Hsp_hseq>
      <Hsp_midline>R+ V+ ++G+G  G VL+C D+K +   VAVK++        AA+  TEL + + +       ++  + + + F+++ H CLV +L  +S+YD M    I R     ++   R ++  + +    GIIH D+KP  IL      +  + P KT          +LSK+    S    + L+    +++DF S    YE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>5.10731e-11</Hsp_evalue>
      <Hsp_query-from>328</Hsp_query-from>
      <Hsp_query-to>732</Hsp_query-to>
      <Hsp_hit-from>366</Hsp_hit-from>
      <Hsp_hit-to>499</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>138</Hsp_align-len>
      <Hsp_qseq>NYRYEVQKMIGEGGQGLVLQCRDHKTKTLVAVKMLSLPLCSSTA--ARQRTELEVAKKLQGRAS-DERYGVIRVLDTFEFRGHNCLVVELLKKSLYDVMSKGSIRRIYVRRLREYTRAILNFLLYAKGRGIIHGDIKP</Hsp_qseq>
      <Hsp_hseq>NRKYLVLDILGQGTFGQVVKCQNLLTKEILAVKVVK----SRTEYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKNHLCLVFELLSNNLYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKP</Hsp_hseq>
      <Hsp_midline>N +Y V  ++G+G  G V++C++  TK ++AVK++     S T    +  TE ++ + L  +     ++  +R+ D+F  + H CLV ELL  +LY+++ +     + ++ +R +T  IL+ L   K   +IH D+KP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1584885299</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0062584-RA transcript Note:&quot;Similar to Dyrk4 Dual specificity tyrosine-phosphorylation-regulated kinase 4 (Mus musculus)&quot; offset:0 AED:0.30 eAED:0.30 QI:0|0.36|0.58|0.58|0.81|0.75|12|1395|343</Iteration_query-def>
  <Iteration_query-len>2427</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YLL019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:105686:107899:-1 gene:YLL019C transcript:YLL019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KNS1 description:Protein kinase involved in negative regulation of PolIII transcription; effector kinase of the TOR signaling pathway and phosphorylates Rpc53p to regulate ribosome and tRNA biosynthesis; member of the LAMMER family of protein kinases, which are serine/threonine kinases also capable of phosphorylating tyrosine residues; capable of autophosphorylation [Source:SGD;Acc:S000003942]</Hit_def>
  <Hit_accession>YLL019C</Hit_accession>
  <Hit_len>737</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>3.04007e-12</Hsp_evalue>
      <Hsp_query-from>550</Hsp_query-from>
      <Hsp_query-to>948</Hsp_query-to>
      <Hsp_hit-from>312</Hsp_hit-from>
      <Hsp_hit-to>443</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>134</Hsp_align-len>
      <Hsp_qseq>RYEVQKMIGEGGQGLVLQCLDHKTK-TLVAVKMLSLPLCSSTAARQRTELEVAKKLQGRASDERYGVIRVLDTFEFRGHNCLVVELLKKSLYDVMSKGSIGRIYVRRLREYTRAILDFLLYAKGRGIIHADIKP</Hsp_qseq>
      <Hsp_hseq>RFVVKDLLGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDRYREAAK--TELRILQTILNNDPQGQFQCLLLRECFDYKNHICLVTDLYGRSIYDFMCSNGIARFPGSHIQAIARQLIRSVCFLHDLGIIHTDLKP</Hsp_hseq>
      <Hsp_midline>R+ V+ ++G+G  G VL+C+D+K +   VAVK++        AA+  TEL + + +       ++  + + + F+++ H CLV +L  +S+YD M    I R     ++   R ++  + +    GIIH D+KP</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>6.71376e-11</Hsp_evalue>
      <Hsp_query-from>127</Hsp_query-from>
      <Hsp_query-to>537</Hsp_query-to>
      <Hsp_hit-from>312</Hsp_hit-from>
      <Hsp_hit-to>451</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>RYEVQKMIGKGGQGLALQCRDHKTK-RLVAVKMLSLPLCSSTAARQRTELEVAKELQGRASDERYGVIQVLDTFEFRGHNCLVVELLKKSLYDVMSKGSIGRIYVRRLREYTRAILDFLLYAKGRGIVHGDIKP----VCKE</Hsp_qseq>
      <Hsp_hseq>RFVVKDLLGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDRYREAAK--TELRILQTILNNDPQGQFQCLLLRECFDYKNHICLVTDLYGRSIYDFMCSNGIARFPGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENILICDE</Hsp_hseq>
      <Hsp_midline>R+ V+ ++G+G  G  L+C D+K +   VAVK++        AA+  TEL + + +       ++  + + + F+++ H CLV +L  +S+YD M    I R     ++   R ++  + +    GI+H D+KP    +C E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>2.51542e-11</Hsp_evalue>
      <Hsp_query-from>550</Hsp_query-from>
      <Hsp_query-to>948</Hsp_query-to>
      <Hsp_hit-from>368</Hsp_hit-from>
      <Hsp_hit-to>499</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>RYEVQKMIGEGGQGLVLQCLDHKTKTLVAVKMLSLPLCSSTA--ARQRTELEVAKKLQGRASD-ERYGVIRVLDTFEFRGHNCLVVELLKKSLYDVMSKGSIGRIYVRRLREYTRAILDFLLYAKGRGIIHADIKP</Hsp_qseq>
      <Hsp_hseq>KYLVLDILGQGTFGQVVKCQNLLTKEILAVKVVK----SRTEYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKNHLCLVFELLSNNLYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKP</Hsp_hseq>
      <Hsp_midline>+Y V  ++G+G  G V++C +  TK ++AVK++     S T    +  TE ++ + L  +     ++  +R+ D+F  + H CLV ELL  +LY+++ +     + ++ +R +T  ILD L   K   +IH D+KP</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>1.6376e-10</Hsp_evalue>
      <Hsp_query-from>121</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>366</Hsp_hit-from>
      <Hsp_hit-to>499</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>144</Hsp_align-len>
      <Hsp_qseq>NYRYEVQKMIGKGGQGLALQCRDHKTKRLVAVKMLSLPLCSSTAARQRTE-----LEVAK--ELQGRASD--ERYGVIQVLDTFEFRGHNCLVVELLKKSLYDVMSKGSIGRIYVRRLREYTRAILDFLLYAKGRGIVHGDIKP</Hsp_qseq>
      <Hsp_hseq>NRKYLVLDILGQGTFGQVVKCQNLLTKEILAVKVV----------KSRTEYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKNHLCLVFELLSNNLYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKP</Hsp_hseq>
      <Hsp_midline>N +Y V  ++G+G  G  ++C++  TK ++AVK++          + RTE     +  AK  EL  +  D   ++  +++ D+F  + H CLV ELL  +LY+++ +     + ++ +R +T  ILD L   K   ++H D+KP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1612026837</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0062585-RA transcript Note:&quot;Similar to DYRK4 Dual specificity tyrosine-phosphorylation-regulated kinase 4 (Homo sapiens)&quot; offset:0 AED:0.24 eAED:0.24 QI:0|0.5|0.66|0.88|0.87|0.77|9|1430|238</Iteration_query-def>
  <Iteration_query-len>2147</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>7.02125e-13</Hsp_evalue>
      <Hsp_query-from>82</Hsp_query-from>
      <Hsp_query-to>615</Hsp_query-to>
      <Hsp_hit-from>353</Hsp_hit-from>
      <Hsp_hit-to>550</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>202</Hsp_align-len>
      <Hsp_qseq>WFFTVDKVRKEQLNYRYEVQKMIGEGGQGLVLQCRDHKTKTLVAVKMLSLPLCSSTA--ARQRTELEVAKKLQGRAS-DERYGVIRVLDTFEFRGHNCLVVELLKKSLYDVMSKGSIGRIYVRRLREYTRAILDFLLYAKGRGIVHGDIKP---ILGMPPK---KMVD------EAPNKTTYFD------PE---GLPYNLS</Hsp_qseq>
      <Hsp_hseq>YILYVNDVLGVEQNRKYLVLDILGQGTFGQVVKCQNLLTKEILAVKVVK----SRTEYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKNHLCLVFELLSNNLYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPELKIIDFGSSCEEARTVYTYIQSRFYRAPEIILGIPYSTS</Hsp_hseq>
      <Hsp_midline>+   V+ V   + N +Y V  ++G+G  G V++C++  TK ++AVK++     S T    +  TE ++ + L  +     ++  +R+ D+F  + H CLV ELL  +LY+++ +     + ++ +R +T  ILD L   K   ++H D+KP   +L  P K   K++D      EA    TY        PE   G+PY+ S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YLL019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:105686:107899:-1 gene:YLL019C transcript:YLL019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KNS1 description:Protein kinase involved in negative regulation of PolIII transcription; effector kinase of the TOR signaling pathway and phosphorylates Rpc53p to regulate ribosome and tRNA biosynthesis; member of the LAMMER family of protein kinases, which are serine/threonine kinases also capable of phosphorylating tyrosine residues; capable of autophosphorylation [Source:SGD;Acc:S000003942]</Hit_def>
  <Hit_accession>YLL019C</Hit_accession>
  <Hit_len>737</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>5.34174e-12</Hsp_evalue>
      <Hsp_query-from>127</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>312</Hsp_hit-from>
      <Hsp_hit-to>443</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>134</Hsp_align-len>
      <Hsp_qseq>RYEVQKMIGEGGQGLVLQCRDHKTK-TLVAVKMLSLPLCSSTAARQRTELEVAKKLQGRASDERYGVIRVLDTFEFRGHNCLVVELLKKSLYDVMSKGSIGRIYVRRLREYTRAILDFLLYAKGRGIVHGDIKP</Hsp_qseq>
      <Hsp_hseq>RFVVKDLLGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDRYREAAK--TELRILQTILNNDPQGQFQCLLLRECFDYKNHICLVTDLYGRSIYDFMCSNGIARFPGSHIQAIARQLIRSVCFLHDLGIIHTDLKP</Hsp_hseq>
      <Hsp_midline>R+ V+ ++G+G  G VL+C D+K +   VAVK++        AA+  TEL + + +       ++  + + + F+++ H CLV +L  +S+YD M    I R     ++   R ++  + +    GI+H D+KP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1405249806</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0062590-RA transcript Note:&quot;Similar to DNAH1 Dynein heavy chain 1, axonemal (Homo sapiens)&quot; offset:0 AED:0.44 eAED:0.44 QI:0|0|0|0.2|1|1|5|0|297</Iteration_query-def>
  <Iteration_query-len>894</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>89</Statistics_hsp-len>
      <Statistics_eff-space>486273403</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0047544-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.33|0.25|4|2|150</Iteration_query-def>
  <Iteration_query-len>452</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>81</Statistics_hsp-len>
      <Statistics_eff-space>164183223</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0047441-RA transcript Note:&quot;Similar to Dnah1 Dynein heavy chain 1, axonemal (Rattus norvegicus)&quot; offset:31 AED:1.00 eAED:1.00 QI:31|0|0|0|0|0|3|0|542</Iteration_query-def>
  <Iteration_query-len>1660</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1047476686</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0036368-RA transcript Note:&quot;Similar to INTS2 Integrator complex subunit 2 (Homo sapiens)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.28|0.25|8|792|153</Iteration_query-def>
  <Iteration_query-len>1254</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>92</Statistics_hsp-len>
      <Statistics_eff-space>752038642</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

