<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0059270-RA transcript Note:&quot;Similar to PRICKLE2 Prickle-like protein 2 (Homo sapiens)&quot; offset:37 AED:0.05 eAED:0.05 QI:37|0.4|0.5|1|0.4|0.5|6|1007|935</BlastOutput_query-def>
  <BlastOutput_query-len>3852</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0059270-RA transcript Note:&quot;Similar to PRICKLE2 Prickle-like protein 2 (Homo sapiens)&quot; offset:37 AED:0.05 eAED:0.05 QI:37|0.4|0.5|1|0.4|0.5|6|1007|935</Iteration_query-def>
  <Iteration_query-len>3852</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2658753461</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058722-RA transcript Note:&quot;Similar to CDH20 Cadherin-20 (Homo sapiens)&quot; offset:0 AED:0.24 eAED:0.29 QI:0|0|0|0.72|1|1|11|0|566</Iteration_query-def>
  <Iteration_query-len>1701</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1079495624</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058723-RA transcript Note:&quot;Similar to Slc6a18 Sodium-dependent neutral amino acid transporter B(0)AT3 (Mus musculus)&quot; offset:0 AED:0.99 eAED:1.00 QI:0|0|0|0.12|1|1|8|0|297</Iteration_query-def>
  <Iteration_query-len>894</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>89</Statistics_hsp-len>
      <Statistics_eff-space>486273403</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0031459-RA transcript Note:&quot;Similar to JARID2 Protein Jumonji (Gallus gallus)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.44|0.5|10|0|914</Iteration_query-def>
  <Iteration_query-len>2745</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>1844704272</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0044039-RA transcript Note:&quot;Similar to Gas8 Dynein regulatory complex subunit 4 (Rattus norvegicus)&quot; offset:365 AED:0.17 eAED:0.17 QI:365|0.12|0.11|0.88|0.25|0.33|9|1331|274</Iteration_query-def>
  <Iteration_query-len>2521</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1682312114</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058724-RA transcript Note:&quot;Similar to MYLIP E3 ubiquitin-protein ligase MYLIP (Homo sapiens)&quot; offset:0 AED:0.43 eAED:0.45 QI:0|0.42|0.5|0.87|1|1|8|0|377</Iteration_query-def>
  <Iteration_query-len>1134</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>663965029</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0044037-RA transcript Note:&quot;Similar to Mylk3 Myosin light chain kinase 3 (Mus musculus)&quot; offset:0 AED:0.48 eAED:0.48 QI:0|0.11|0|0.5|0.33|0.5|10|0|542</Iteration_query-def>
  <Iteration_query-len>1629</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>108.227</Hsp_bit-score>
      <Hsp_score>269</Hsp_score>
      <Hsp_evalue>4.30417e-25</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>95</Hsp_hit-from>
      <Hsp_hit-to>224</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>132</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPEVVN-YEFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>RLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHK--YNIKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFAL</Hsp_hseq>
      <Hsp_midline>+L+D +E+ +D+ L++EY E GELFN ++++  L E + + F RQI  GV Y H   I+H DLKPEN+L   +  Y IKI DFG+A      + L+ S G+  + APE+V+   +  F +D+WS GVI + L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>108.227</Hsp_bit-score>
      <Hsp_score>269</Hsp_score>
      <Hsp_evalue>4.4712e-25</Hsp_evalue>
      <Hsp_query-from>1237</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>179</Hsp_hit-from>
      <Hsp_hit-to>308</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>131</Hsp_align-len>
      <Hsp_qseq>LFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPEVV-NYEFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>LFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLL-LDKKNRRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFAL</Hsp_hseq>
      <Hsp_midline>LF+ +E++S++ L++EYV+GGELF+ ++ +  L E + + + +QI EGV Y H   I H DLKPEN+L L +   +IKI DFG+A    P + LK S G+  + +PE+V    +   P+D+WS G++ + L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>105.531</Hsp_bit-score>
      <Hsp_score>262</Hsp_score>
      <Hsp_evalue>2.91504e-24</Hsp_evalue>
      <Hsp_query-from>1237</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>92</Hsp_hit-from>
      <Hsp_hit-to>220</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>131</Hsp_align-len>
      <Hsp_qseq>LFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPEVVN-YEFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>LYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDS--FYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFAL</Hsp_hseq>
      <Hsp_midline>L+D +E+ +++ LI+EY E GELFN ++D   L E + +   RQI  G+ Y H   I+H DLKPEN+L  S   Y IKI DFG+A      + L+ S G+  + APE+V+   +  F +D+WS GVI + L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>99.7525</Hsp_bit-score>
      <Hsp_score>247</Hsp_score>
      <Hsp_evalue>5.80322e-23</Hsp_evalue>
      <Hsp_query-from>1243</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>103</Hsp_hit-from>
      <Hsp_hit-to>232</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>130</Hsp_align-len>
      <Hsp_qseq>DAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQ-IKIIDFGLARRYKPREKLKVS-FGTSEFLAPEVVNYEFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>DWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTL</Hsp_hseq>
      <Hsp_midline>D +ES+    +I +  +GGELF+RI+ +   +E D V  + +I   V YMH Q I+H DLKPEN+L + +     + + DFG+A+R K  E+L     G+  ++APEV+  +    P D+WS+GVITY L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>97.4413</Hsp_bit-score>
      <Hsp_score>241</Hsp_score>
      <Hsp_evalue>3.92761e-22</Hsp_evalue>
      <Hsp_query-from>1243</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>113</Hsp_hit-from>
      <Hsp_hit-to>242</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>130</Hsp_align-len>
      <Hsp_qseq>DAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRW-GYQIKIIDFGLARRYKPREKLKV-SFGTSEFLAPEVVNYEFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>DWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTL</Hsp_hseq>
      <Hsp_midline>D +ES+    ++ +   GGELF+RI+ +   +E+D V  + QI   V YMH + ++H DLKPEN+L + +     + I DFG+A++ K  E L   + G+  ++APEV+  +    P D+WS+GVITY L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>94.3597</Hsp_bit-score>
      <Hsp_score>233</Hsp_score>
      <Hsp_evalue>7.79967e-21</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>117</Hsp_hit-from>
      <Hsp_hit-to>245</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>132</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPEVVNYEFVSFP-TDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>KLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLN--VKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVM</Hsp_hseq>
      <Hsp_midline>KL+D  +S+ +I +++EY  G ELF+ I+ +  +SE +   F +QI   V Y H+  I+H DLKPEN+L        +KI DFGL+        LK S G+  + APEV++ +  + P  D+WS GVI Y++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.2705</Hsp_bit-score>
      <Hsp_score>212</Hsp_score>
      <Hsp_evalue>1.93105e-18</Hsp_evalue>
      <Hsp_query-from>1207</Hsp_query-from>
      <Hsp_query-to>1623</Hsp_query-to>
      <Hsp_hit-from>252</Hsp_hit-from>
      <Hsp_hit-to>413</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>162</Hsp_align-len>
      <Hsp_qseq>VIRVKSPK-EKLFDAYE---SRSDIT--LIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILC------------LSRW-----GYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPEVVNYEFVSFPTDMWSVGVITYM</Hsp_qseq>
      <Hsp_hseq>LMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVILYV</Hsp_hseq>
      <Hsp_midline>++RV+ P    L D++    S+S I   L++E ++ GELF RI+ ++ L + ++    +Q+  G+ Y+H+Q I+H D+KPENIL             L  W       Q+KI DFGLA+     +      GT  ++APEV+  +  +   D+WS GVI Y+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.0409</Hsp_bit-score>
      <Hsp_score>214</Hsp_score>
      <Hsp_evalue>2.59539e-18</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>187</Hsp_hit-from>
      <Hsp_hit-to>316</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>132</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPEVVNYEFVSFP-TDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>RLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSG--EIKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVL</Hsp_hseq>
      <Hsp_midline>+LF+     +   ++ EYV GG+L + II    L E     F R I   + Y+H   I+H DLK ENI+  S    +IKIIDFGL+  +  R++L    G+  F APE++  +  + P  D+WS G++ Y+L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.6481</Hsp_bit-score>
      <Hsp_score>200</Hsp_score>
      <Hsp_evalue>3.17197e-17</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>149</Hsp_hit-from>
      <Hsp_hit-to>275</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>131</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPEVVNYEFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>RMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENIL-LDKNGH-IKITDFGFA-KYVPDVTYTLC-GTPDYIAPEVVSTKPYNKSIDWWSFGILIYEM</Hsp_hseq>
      <Hsp_midline>+++  ++    I +IM+Y+EGGELF+ +             +  ++C  + Y+H + I++ DLKPENIL L + G+ IKI DFG A +Y P     +  GT +++APEVV+ +  +   D WS G++ Y +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.1889</Hsp_bit-score>
      <Hsp_score>204</Hsp_score>
      <Hsp_evalue>3.92716e-17</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>208</Hsp_hit-from>
      <Hsp_hit-to>337</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>132</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPEVVNYEFVSFP-TDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>RLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISD--SSEIKIIDFGLSNIYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVL</Hsp_hseq>
      <Hsp_midline>+LF+     +   ++ EYV GG+L + II    + E     F R I   + Y+H   I+H DLK ENI+       +IKIIDFGL+  Y  R++L    G+  F APE++     + P  D+WS GV+ ++L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.2629</Hsp_bit-score>
      <Hsp_score>199</Hsp_score>
      <Hsp_evalue>4.54747e-17</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>150</Hsp_hit-from>
      <Hsp_hit-to>276</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>131</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPEVVNYEFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>RMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENIL-LDKNGH-IKITDFGFA-KYVPDVTYTLC-GTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEM</Hsp_hseq>
      <Hsp_midline>+++  ++    + ++M+Y+EGGELF+ +             +  ++C  + Y+H + I++ DLKPENIL L + G+ IKI DFG A +Y P     +  GT +++APEVV+ +  +   D WS GV+ Y +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.2629</Hsp_bit-score>
      <Hsp_score>199</Hsp_score>
      <Hsp_evalue>1.44668e-16</Hsp_evalue>
      <Hsp_query-from>1237</Hsp_query-from>
      <Hsp_query-to>1617</Hsp_query-to>
      <Hsp_hit-from>625</Hsp_hit-from>
      <Hsp_hit-to>758</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>LFDAY-ESRSDITLIMEYVEGGELFNRIID-------QSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGL-ARRYKPREKLKVSFGTSEFLAPEVVNYEFVSFPTDMWSVGVIT</Hsp_qseq>
      <Hsp_hseq>FLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTR--ARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMT</Hsp_hseq>
      <Hsp_midline>  +AY  +  D+ ++ME++EGG L + I +        S L+E      VR+ C+G+ ++H ++I+H D+K +N+L  +R   ++KI DFG  AR    R K     GT  ++APEVV         D+WS+G++T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.4925</Hsp_bit-score>
      <Hsp_score>197</Hsp_score>
      <Hsp_evalue>1.89757e-16</Hsp_evalue>
      <Hsp_query-from>1252</Hsp_query-from>
      <Hsp_query-to>1623</Hsp_query-to>
      <Hsp_hit-from>394</Hsp_hit-from>
      <Hsp_hit-to>520</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>130</Hsp_align-len>
      <Hsp_qseq>ESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSF-----GTSEFLAP-EVVNYEFVSFPTDMWSVGVITYM</Hsp_qseq>
      <Hsp_hseq>DAKGEYCEVMEYCAGGDLFTLVVAAGKLEYMEADCFFKQLIRGVVYMHEMGVCHRDLKPENLL-LTHDGV-LKITDFGNSECFKMAWEKNIHLSGGVCGSSPYIAPEEYIKEEFDPRPVDIWACGVI-YM</Hsp_hseq>
      <Hsp_midline>+++ +   +MEY  GG+LF  ++    L  ++   F +Q+  GV YMH+  + H DLKPEN+L L+  G  +KI DFG +  +K   +  +       G+S ++AP E +  EF   P D+W+ GVI YM</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.5666</Hsp_bit-score>
      <Hsp_score>192</Hsp_score>
      <Hsp_evalue>7.49909e-16</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>143</Hsp_hit-from>
      <Hsp_hit-to>274</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>134</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSF-GTSEFLAPEVV--NYEFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>QFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDS--NYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYAL</Hsp_hseq>
      <Hsp_midline>+  D +E  S++ +++E    G L   +  +  L+E +   F  QIC  + YMH + ++H DLK  NI   S   Y +KI DFGLA       + K +  GT  ++APEV+   +   SF  D+WS+GV+ Y L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.2554</Hsp_bit-score>
      <Hsp_score>186</Hsp_score>
      <Hsp_evalue>1.74441e-15</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1620</Hsp_query-to>
      <Hsp_hit-from>132</Hsp_hit-from>
      <Hsp_hit-to>256</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>132</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSF---GTSEFLAPEVVNYEFVSFPTDMWSVGVITY</Hsp_qseq>
      <Hsp_hseq>RMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENIL-LDRNGH-IKITDFGFA-----KEVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIY</Hsp_hseq>
      <Hsp_midline>+++  ++   +I ++M+Y+EGGELF+ +             +  ++   + Y+H   I++ DLKPENIL L R G+ IKI DFG A     +E   V++   GT +++APEV+  +  +   D WS+GV+ Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.7962</Hsp_bit-score>
      <Hsp_score>190</Hsp_score>
      <Hsp_evalue>1.97952e-15</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>242</Hsp_hit-from>
      <Hsp_hit-to>382</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>143</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPRE------------KLKVSFGTSEFLAPEVVNYEFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>RLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGE--MKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQM</Hsp_hseq>
      <Hsp_midline>+LF  ++  S +  ++EY   G+  + +     L E     +  QI + + Y+H   I+H D+KPENIL       +IK+ DFG A+   P              + K   GT+E+++PE++N  F  +  D+W+ G I + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.8702</Hsp_bit-score>
      <Hsp_score>185</Hsp_score>
      <Hsp_evalue>4.28359e-15</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>80</Hsp_hit-from>
      <Hsp_hit-to>215</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>138</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQY-ILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPRE-KLKVSF---GTSEFLAPEVVNYE--FVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>RLIDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENIL-LDKNG-NLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVL</Hsp_hseq>
      <Hsp_midline>+L D   S+  + +I+E  +GG+LF++I    G+       + +Q+   ++Y+H +  + H D+KPENIL L + G  +K+ DFGLA +++ ++  L+VS    G+  ++APEV+  E  + +  TD+WS+G++ ++L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.3294</Hsp_bit-score>
      <Hsp_score>181</Hsp_score>
      <Hsp_evalue>6.46909e-15</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>166</Hsp_hit-from>
      <Hsp_hit-to>294</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>133</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQ--IKIIDFGLARRYKPREKLKVSFGTSEFLAPEVVNYEFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>KSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILI----GFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFEL</Hsp_hseq>
      <Hsp_midline>K +  +     + L+MEY+  GE++  +      +++    ++ QI   + YMH++ I+H D+KPENIL     G+   IK+ DFG +    P  + K   GT ++L+PE+V         D W++GV+ + L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.3294</Hsp_bit-score>
      <Hsp_score>181</Hsp_score>
      <Hsp_evalue>1.89286e-14</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>96</Hsp_hit-from>
      <Hsp_hit-to>225</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>132</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPEVVNYE-FVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>KLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSMHCVHRDLKLENIL-LDKNG-NAKLTDFGFTRECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTL</Hsp_hseq>
      <Hsp_midline>KL++   + S + + +EY  G EL++ ++    +S L+      QI   V+Y H  + +H DLK ENIL L + G   K+ DFG  R    +  L+   GT+ ++APE++    +  F  D+WS+GVI Y L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.9442</Hsp_bit-score>
      <Hsp_score>180</Hsp_score>
      <Hsp_evalue>2.42941e-14</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>114</Hsp_hit-from>
      <Hsp_hit-to>245</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>134</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKL-KVSFGTSEFLAPEVV--NYEFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>KLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLL--DKNENLVITDFGFVNEFCSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAI</Hsp_hseq>
      <Hsp_midline>KL +  ++   I +++EY  GGE +  I  +  L E++      Q+  GVHY+H + ++H DLK EN+L        + I DFG    +  R +L K S G+  + APE+V     + +   D+WS GVI Y +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.559</Hsp_bit-score>
      <Hsp_score>179</Hsp_score>
      <Hsp_evalue>4.01818e-14</Hsp_evalue>
      <Hsp_query-from>1249</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>263</Hsp_hit-from>
      <Hsp_hit-to>401</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>139</Hsp_align-len>
      <Hsp_qseq>YESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPEVVNYEFVSFP-------------TDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>YEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVI</Hsp_hseq>
      <Hsp_midline>YE      ++ME+V GG+L + +     + E       RQI   + Y+H   I H DLKP+NIL        +KI DFGLA+       +K   GT  ++APEV+  +  S                DMWS+G + Y++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>9.99613e-14</Hsp_evalue>
      <Hsp_query-from>1204</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>187</Hsp_hit-from>
      <Hsp_hit-to>349</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>164</Hsp_align-len>
      <Hsp_qseq>KVIRVKSPKEKLFDAY-ESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILC--LSRWGYQ--------------------IKIIDFGLARRYKPREKLKVSFGTSEFLAPEVVNYEFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>KLVSKNNPHCTKFIAFQESANYYYLVTELVTGGEIFDRIVQLTCFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLR-NNTAKTPCGTIEYVASEVFTSKRYSMKVDMWSIGCVLFTL</Hsp_hseq>
      <Hsp_midline>K++   +P    F A+ ES +   L+ E V GGE+F+RI+  +  SE      + Q+   + +MH   I+H D+KPEN+L   +  +G                      +K++DFGLA++ +     K   GT E++A EV   +  S   DMWS+G + + L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>1.96376e-13</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>188</Hsp_hit-from>
      <Hsp_hit-to>330</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>146</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPRE---------------KLKVSFGTSEFLAPEVVNYEFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>KLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILL--DKNMKVKLTDFGTAKIL-PEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQM</Hsp_hseq>
      <Hsp_midline>KLF  ++  + +  ++EY   G+    I     L+E     +  QI + V  +H   I+H D+KPENIL       ++K+ DFG A+   P E               K K   GT+E+++PE++N  +     D+W+ G I Y +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>2.82173e-13</Hsp_evalue>
      <Hsp_query-from>1264</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>447</Hsp_hit-from>
      <Hsp_hit-to>571</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>128</Hsp_align-len>
      <Hsp_qseq>DITLIMEYVEGGELFNRIID----------QSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRY-KPREKLKVSFGTSEFLAPEVVNYEFVSFPTDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>ELWVIMEYMEGGCLTD-ILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNIL-LNSQGL-VKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIM</Hsp_hseq>
      <Hsp_midline>++ +IMEY+EGG L + I+D           S L+E      V++ C+G+ ++H + I+H D+K +NIL L+  G  +KI DFG      + R K     GT  ++APE+VN +      D+WS+G++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>4.01043e-13</Hsp_evalue>
      <Hsp_query-from>1198</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>212</Hsp_hit-from>
      <Hsp_hit-to>378</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>167</Hsp_align-len>
      <Hsp_qseq>AAKVIRVKSPKE-KLFDAYESRSD-ITLIMEYVEGGELFNRIID---QSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENI-LCLSRWGYQIKIIDFGLARRYKP-REKLKVSFGTSEFLAPEV---VNYE-FVSFP-------------TDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>ARILLRLDHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIM</Hsp_hseq>
      <Hsp_midline>A  ++R+  P   K++  +  R++ + +  + + GG+LF+ +      + +SE +++L V QI + ++Y+H Q I+H DLK +NI LC      +I + DFG+A+     +E++    GT E+ APEV    N + + SF               D+WS+GVIT+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>4.11987e-13</Hsp_evalue>
      <Hsp_query-from>1246</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>481</Hsp_hit-from>
      <Hsp_hit-to>605</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>128</Hsp_align-len>
      <Hsp_qseq>AYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPEVVNYEF-VSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>SFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENIL-LDANG-NIALCDFGLSKA-DLKDRTNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEM</Hsp_hseq>
      <Hsp_midline>++++ +D+ L+ +Y+ GGELF  +  +   SE     ++ ++   + ++H   I++ DLKPENIL L   G  I + DFGL++    +++     GT+E+LAPE++  E   +   D WS+GV+ + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>4.20286e-13</Hsp_evalue>
      <Hsp_query-from>1267</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>125</Hsp_hit-from>
      <Hsp_hit-to>245</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>123</Hsp_align-len>
      <Hsp_qseq>ITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARR-YKPREKLKVSFGTSEFLAPEVV--NYEFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>IGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHEN--LVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAM</Hsp_hseq>
      <Hsp_midline>I +++E+V GGE +  I  +  L E        Q+  GV+YMH + ++H DLK EN+L        + I DFG     ++  E +K S G+  + APE+V     + +   D+WS GVI Y +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>5.56348e-13</Hsp_evalue>
      <Hsp_query-from>1237</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>680</Hsp_hit-from>
      <Hsp_hit-to>803</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>127</Hsp_align-len>
      <Hsp_qseq>LFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPRE-KLKVSFGTSEFLAPEVVNYEFVSFPTDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>FIDSYVLKGDLWVIMEYMEGGSLTD-VVTHCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNIL-LSMEG-DIKLTDFGFCAQINELNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIM</Hsp_hseq>
      <Hsp_midline>  D+Y  + D+ +IMEY+EGG L + ++    L+E       R+   G+ ++H + +LH D+K +NIL LS  G  IK+ DFG   +      K     GT  ++APEVV+ +      D+WS+G++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>5.95548e-13</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>77</Hsp_hit-from>
      <Hsp_hit-to>223</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>149</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKP------------------REKLKVSFGTSEFLAPEVVNYEFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>KLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVL-LDRDG-RLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQF</Hsp_hseq>
      <Hsp_midline>KL+  +    ++  ++++  GGEL + +      +++ T  F  Q+ + + ++H   I+H DLKPEN+L L R G ++ I DFG A    P                   +      GT+E+++PE++ Y    + +D+W++G + Y  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YKL168C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:131288:133462:-1 gene:YKL168C transcript:YKL168C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KKQ8 description:Putative serine/threonine protein kinase with unknown cellular role; KKQ8 has a paralog, HAL5, that arose from the whole genome duplication [Source:SGD;Acc:S000001651]</Hit_def>
  <Hit_accession>YKL168C</Hit_accession>
  <Hit_len>724</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>9.07918e-13</Hsp_evalue>
      <Hsp_query-from>1180</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>477</Hsp_hit-from>
      <Hsp_hit-to>633</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>IIGLTLAAKVIRVKSPKEKL---FDAYESRSDITLIMEYVEGGELFNRIIDQSGLS----ELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVS-----FGTSEFLAP-EVVNYEFVSFP--TDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>IIGHSLSHYHKNGKKPAPNILNVFDILEDSSSFIEVMEFCPAGDLYGMLVGKSKLKGRLHPLEADCFMKQLLHGVKFMHDHGIAHCDLKPENILFYPHG--LLKICDFGTSSVFQTAWERRVHAQKGIIGSEPYVAPEEFVDGEYYD-PRLIDCWSCGVV</Hsp_hseq>
      <Hsp_midline>IIG +L+      K P   +   FD  E  S    +ME+   G+L+  ++ +S L      L+   F++Q+  GV +MH   I H DLKPENIL        +KI DFG +  ++   + +V       G+  ++AP E V+ E+   P   D WS GV+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YMR291W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:852630:854390:1 gene:YMR291W transcript:YMR291W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TDA1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000004905]</Hit_def>
  <Hit_accession>YMR291W</Hit_accession>
  <Hit_len>586</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.5514</Hsp_bit-score>
      <Hsp_score>166</Hsp_score>
      <Hsp_evalue>1.17141e-12</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>118</Hsp_hit-from>
      <Hsp_hit-to>285</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>168</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGGELFNRIIDQSGLS-ELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSR--------------------WGYQIKIIDFGLARRYKPRE--KLKVSFGTSEFLAPEVVNYEFV--------------SFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>QLFDYFETADNIVLITQLCQKGDLYEKIVENQCLDLETQVTSYCACLVSVLEFLHSQGIVHRDLKAENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLVLADFGLAAEYNTSKVNSLKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGCPVDIWALGVLTYFM</Hsp_hseq>
      <Hsp_midline>+LFD +E+  +I LI +  + G+L+ +I++   L  E     +   +   + ++H Q I+H DLK EN+L   R                      + + + DFGLA  Y   +   LK   GT  ++APE+V  + V                P D+W++GV+TY +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>2.17083e-12</Hsp_evalue>
      <Hsp_query-from>1246</Hsp_query-from>
      <Hsp_query-to>1620</Hsp_query-to>
      <Hsp_hit-from>410</Hsp_hit-from>
      <Hsp_hit-to>533</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>126</Hsp_align-len>
      <Hsp_qseq>AYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLAR-RYKPREKLKVSFGTSEFLAPEVVNYEFVSFPTDMWSVGVITY</Hsp_qseq>
      <Hsp_hseq>SFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENIL-LDYQGH-IALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLY</Hsp_hseq>
      <Hsp_midline>+++S   + L++ ++ GGELF  +  +   S   +  ++ ++   +  +H+  +++ DLKPENIL L   G+ I + DFGL +   K  +K     GT E+LAPE++  +  +   D W++G++ Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YJL165C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:106894:109461:-1 gene:YJL165C transcript:YJL165C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HAL5 description:Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters; HAL5 has a paralog, KKQ8, that arose from the whole genome duplication [Source:SGD;Acc:S000003701]</Hit_def>
  <Hit_accession>YJL165C</Hit_accession>
  <Hit_len>855</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>3.20844e-12</Hsp_evalue>
      <Hsp_query-from>1195</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>584</Hsp_hit-from>
      <Hsp_hit-to>758</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>177</Hsp_align-len>
      <Hsp_qseq>LAAKVIRVKSPKE--------KLFDAYESRSDITLIMEYVEGGELF-----NRIIDQSG-----------------LSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSF-----GTSEFLAPE--VVNYEFVSFPTDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>IAGNVSRTTPPKHVFNAPNILKILDLMEYSNSFVEVMEFCASGDLYSLLTRNNISNESNNGSSRLIQTVKEGSGSPLHPLEADCFMKQLLNGVQYMHDHGIAHCDLKPENILF--QPNGLLKICDFGTSSVFQTAWEKHVHFQSGAMGSEPYVAPEEFIRDAEYDPRLVDCWSCGIV</Hsp_hseq>
      <Hsp_midline>+A  V R   PK         K+ D  E  +    +ME+   G+L+     N I ++S                  L  L+   F++Q+  GV YMH   I H DLKPENIL   +    +KI DFG +  ++   +  V F     G+  ++APE  + + E+     D WS G++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>3.2242e-12</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1620</Hsp_query-to>
      <Hsp_hit-from>216</Hsp_hit-from>
      <Hsp_hit-to>353</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>140</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRY-----------KPREKLKVSFGTSEFLAPEVVNYEFVSFPTDMWSVGVITY</Hsp_qseq>
      <Hsp_hseq>KLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCL-LNQRGHLV-LTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLY</Hsp_hseq>
      <Hsp_midline>KLF ++   S + L+++Y+ GGELF  + +   L E     +  +I   + ++H + +++ DLKPEN L L++ G+ + + DFGL+++            +    L    GT E+ APE++  +  S   D +S+G + Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>4.23291e-12</Hsp_evalue>
      <Hsp_query-from>1240</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>520</Hsp_hit-from>
      <Hsp_hit-to>646</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>129</Hsp_align-len>
      <Hsp_qseq>FDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKP---REKLKVSFGTSEF-LAPEVVNYEFVSFPTDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>YGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGC--VKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCV</Hsp_hseq>
      <Hsp_midline>+ A +   ++ + +EYV GG + + + +     E     F RQI  GV Y+H++ I+H D+K  NIL   +    +KI DFG++++  P   ++  + S   S F ++PEVV     +   D+WS G +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>5.43971e-12</Hsp_evalue>
      <Hsp_query-from>1219</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>1158</Hsp_hit-from>
      <Hsp_hit-to>1297</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>144</Hsp_align-len>
      <Hsp_qseq>KSPKE---KLFDAYESRSDITLIMEYVEGG----ELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPEVV-NYEFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>KKPHENILRLLDFFED-DDYYYIETPVHGETGCIDLFDLIEFKTNMTEFEAKLIFKQVVAGIKHLHDQGIVHRDIKDENVIVDSK-GF-VKIIDFGSA-AYVKSGPFDVFVGTIDYAAPEVLGGNPYEGQPQDIWAIGILLYTV</Hsp_hseq>
      <Hsp_midline>K P E   +L D +E   D   I   V G     +LF+ I  ++ ++E +  L  +Q+  G+ ++H Q I+H D+K EN++  S+ G+ +KIIDFG A  Y       V  GT ++ APEV+    +   P D+W++G++ Y +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>4.37991e-11</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>68</Hsp_hit-from>
      <Hsp_hit-to>194</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>130</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGGELFNRIIDQSGL-SELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRY-KPREKLKVSFGTSEFLAPEVV-NYEFVSFPTDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>ELIDIFMAYDNLNLVLEFLPT-DLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLL-FSPDG-QIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVI</Hsp_hseq>
      <Hsp_midline>+L D + +  ++ L++E++   +L   I D+S L +  D   ++     GV++ H+ +ILH DLKP N+L  S  G QIK+ DFGLAR    P E L  +  T  + APE++   +  +   D+WSVGVI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YFL033C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:69115:74427:-1 gene:YFL033C transcript:YFL033C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM15 description:Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase [Source:SGD;Acc:S000001861]</Hit_def>
  <Hit_accession>YFL033C</Hit_accession>
  <Hit_len>1770</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>6.99713e-11</Hsp_evalue>
      <Hsp_query-from>1207</Hsp_query-from>
      <Hsp_query-to>1494</Hsp_query-to>
      <Hsp_hit-from>845</Hsp_hit-from>
      <Hsp_hit-to>941</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>99</Hsp_align-len>
      <Hsp_qseq>VIRVKSPKE---KLFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLAR</Hsp_qseq>
      <Hsp_hseq>IMMVQSDKPYVARLFASFQNKDNLFLVMEYLPGGDLATLIKMMGYLPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLL-IDNAGH-VKLTDFGLSR</Hsp_hseq>
      <Hsp_midline>++ V+S K    +LF +++++ ++ L+MEY+ GG+L   I     L +     ++ +I  GV+ MHQ  I+H DLKPEN+L +   G+ +K+ DFGL+R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>8.4473e-11</Hsp_evalue>
      <Hsp_query-from>1237</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>253</Hsp_hit-from>
      <Hsp_hit-to>413</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>162</Hsp_align-len>
      <Hsp_qseq>LFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENIL--------------------------------CLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPEVVNYEFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>FIDFQETDSYYYIIQELLTGGEIFGEIVRLTYFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSK-NTKTPCGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTM</Hsp_hseq>
      <Hsp_midline>  D  E+ S   +I E + GGE+F  I+  +  SE  +   ++Q+   V +MH   ++H D+KPEN+L                                        +K+ DFGL+++   +   K   GT  + APEVV  E  S   DMW +G + Y +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>9.10947e-11</Hsp_evalue>
      <Hsp_query-from>1237</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>890</Hsp_hit-from>
      <Hsp_hit-to>1017</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>131</Hsp_align-len>
      <Hsp_qseq>LFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSF-GTSEFLAPEVVNYEFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>LYCSFQTENRIYFAMEFIGGGDLMWHVQNQR-LSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENIL-LTPEGH-IKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQM</Hsp_hseq>
      <Hsp_midline>L+ ++++ + I   ME++ GG+L   + +Q  LS      +  ++   + Y H   +++ DLK ENIL L+  G+ IKI D+GL +          +F GT EF+APE++  +  +   D W+ GV+ Y +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>1.13296e-10</Hsp_evalue>
      <Hsp_query-from>1237</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>153</Hsp_hit-from>
      <Hsp_hit-to>278</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>LFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVL-FVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPEVVNYE---------FVSFPTDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>FFDSY-------IIMEYCSGGDLYEAIKADAVPKKTKSITHIITQIMDAIEYVHNKGIYHRDIKPENIL-ISGIDWTIKLTDWGLATTDK--TSMDRNVGSERYMSPELFDSNLDIKERKEPYDCAKVDLWAMGIV</Hsp_hseq>
      <Hsp_midline> FD+Y       +IMEY  GG+L+  I   +   +  ++   + QI + + Y+H + I H D+KPENIL +S   + IK+ D+GLA   K    +  + G+  +++PE+ +           +     D+W++G++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>1.69146e-10</Hsp_evalue>
      <Hsp_query-from>1273</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>91</Hsp_hit-from>
      <Hsp_hit-to>210</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>122</Hsp_align-len>
      <Hsp_qseq>LIMEYVEGGELFNRIIDQ--SGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPEVVNYEFVSF--PTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>IVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANIL-LNEEG-MVKLGDFGVSGHIRSTLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYEL</Hsp_hseq>
      <Hsp_midline>++MEY  GG   + +     +GL E      + ++  G+ Y+H+Q  +H D+K  NIL L+  G  +K+ DFG++   +   K     GT  ++APEVV  E   +    D+WS+G+ TY L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>2.30166e-10</Hsp_evalue>
      <Hsp_query-from>1252</Hsp_query-from>
      <Hsp_query-to>1611</Hsp_query-to>
      <Hsp_hit-from>283</Hsp_hit-from>
      <Hsp_hit-to>403</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>125</Hsp_align-len>
      <Hsp_qseq>ESRSDITLIMEYVEGGEL---FNRIIDQSG-LSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSF-GTSEFLAPEVVNYEFVSFPTDMWSVGV</Hsp_qseq>
      <Hsp_hseq>EQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNIL-LNEKG-EIKLCDFGVSG--EAVNSLAMTFTGTSFYMAPERIQGQPYSVTCDVWSLGL</Hsp_hseq>
      <Hsp_midline>E  S I + MEY+ G  L   +  ++ + G +SE         +  G+ Y+H++ ++H D+KP+NIL L+  G +IK+ DFG++   +    L ++F GTS ++APE +  +  S   D+WS+G+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>2.77412e-10</Hsp_evalue>
      <Hsp_query-from>1252</Hsp_query-from>
      <Hsp_query-to>1611</Hsp_query-to>
      <Hsp_hit-from>290</Hsp_hit-from>
      <Hsp_hit-to>410</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>125</Hsp_align-len>
      <Hsp_qseq>ESRSDITLIMEYVEGGEL---FNRIIDQSG-LSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSF-GTSEFLAPEVVNYEFVSFPTDMWSVGV</Hsp_qseq>
      <Hsp_hseq>DENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNIL-LNENG-QVKLCDFGVSG--EAVNSLATTFTGTSFYMAPERIQGQPYSVTSDVWSLGL</Hsp_hseq>
      <Hsp_midline>+  S I + MEY+ G  L   +  ++++ G +SE         +  G+ Y+H++ ++H D+KP+NIL L+  G Q+K+ DFG++   +    L  +F GTS ++APE +  +  S  +D+WS+G+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>3.93718e-10</Hsp_evalue>
      <Hsp_query-from>1237</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>387</Hsp_hit-from>
      <Hsp_hit-to>535</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>151</Hsp_align-len>
      <Hsp_qseq>LFDAYESRSDITLIMEYVEGGELFNRIIDQSG--LSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRY----KPREKLKV--------------SF-GTSEFLAPEVVNYEFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>LYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENIL-LHQSGH-VMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEM</Hsp_hseq>
      <Hsp_midline>L+ +++++  + L MEY  GGE F  +  +    ++E D   +  ++   + Y+H    ++ DLKPENIL L + G+ + + DF L+ +     KP  K                 SF GT E+LAPEV+     +   D W++G++ Y +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>5.69817e-10</Hsp_evalue>
      <Hsp_query-from>1237</Hsp_query-from>
      <Hsp_query-to>1611</Hsp_query-to>
      <Hsp_hit-from>421</Hsp_hit-from>
      <Hsp_hit-to>552</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>135</Hsp_align-len>
      <Hsp_qseq>LFDAYESRSDITLIMEYVEGGELFNRIIDQS----GLSELDTVLFVRQICEGVHYMHQQY-ILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPEVV---NYEFVSFP--TDMWSVGV</Hsp_qseq>
      <Hsp_hseq>FYGAFFIEGAVYMCMEYMDGGSL-DKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSANQG-TVKLCDFGVSGNLV-ASLAKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGL</Hsp_hseq>
      <Hsp_midline> + A+     + + MEY++GG L ++I D+S    G+ E         +  G+  + +Q+ I+H D+KP NILC +  G  +K+ DFG++         K + G   ++APE +   N +  ++   +D+WS+G+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>6.05698e-10</Hsp_evalue>
      <Hsp_query-from>1246</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>413</Hsp_hit-from>
      <Hsp_hit-to>538</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>128</Hsp_align-len>
      <Hsp_qseq>AYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLAR-RYKPREKLKVSFGTSEFLAPEVVNYEFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>SFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENIL-LDYQGH-IALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEM</Hsp_hseq>
      <Hsp_midline>+++S   +  ++ ++ GGELF  +  +          +  ++   +  +H+  +++ DLKPENIL L   G+ I + DFGL +   K  +K     GT E+LAPE++     +   D W++GV+ Y +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>1.23181e-09</Hsp_evalue>
      <Hsp_query-from>1237</Hsp_query-from>
      <Hsp_query-to>1620</Hsp_query-to>
      <Hsp_hit-from>88</Hsp_hit-from>
      <Hsp_hit-to>258</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>LFDAYESRSDITLIMEYVEGGEL---------------FNRII---------DQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRW-GYQ------------------IKIIDFGLARRYKPREKLKVSF-GTSEFLAPEVVNYEFVSFPTDMWSVGVITY</Hsp_qseq>
      <Hsp_hseq>LIDCERTSTDFYLIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFAR-FLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVVF</Hsp_hseq>
      <Hsp_midline>L D   + +D  LIMEY   G+L                 R +         + +GL     + +++Q+   + ++  + ++H D+KP+N+L  +   GY                   +KI DFG AR + P   L  +  G+  ++APE++NY+  +   D+WSVG + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>1.39999e-09</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>67</Hsp_hit-from>
      <Hsp_hit-to>198</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGGELFNRIIDQSGLS------ELDTVLFVR-QICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYK-PREKLKVSFGTSEFLAPEVV-NYEFVSFPTDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>RLYDVIHTENKLTLVFEFMDND--LKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRG--QLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCI</Hsp_hseq>
      <Hsp_midline>+L+D   + + +TL+ E+++      + +D   +       EL+ V + + Q+ +G+ + H+  ILH DLKP+N+L   R   Q+K+ DFGLAR +  P         T  + AP+V+      S   D+WS G I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>1.60496e-09</Hsp_evalue>
      <Hsp_query-from>1207</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>241</Hsp_hit-from>
      <Hsp_hit-to>397</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>161</Hsp_align-len>
      <Hsp_qseq>VIRVKSPKEKLFDAYES------RSDITLIMEYVEGGEL------FNRIIDQSGLS-------ELDTVLFVRQICEGVHYMHQQY-ILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSF-GTSEFLAPEVVNYEFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>IVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKG--QIKLCDFGVSKKLI--NSIADTFVGTSTYMSPERIQGNVYSIKGDVWSLGLMIIEL</Hsp_hseq>
      <Hsp_midline>+++   P E +   Y +       ++I ++MEY + G L      + R + +  +S       EL        +  G+ ++++QY I+H D+KP N+L  S+   QIK+ DFG++++      +  +F GTS +++PE +     S   D+WS+G++   L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.5362</Hsp_bit-score>
      <Hsp_score>140</Hsp_score>
      <Hsp_evalue>1.926e-09</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>911</Hsp_hit-from>
      <Hsp_hit-to>1042</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGG----ELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPEVV-NYEFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>KLLDFFED-DDYYYIETPVHGETGSIDLFDVIEFKKDMVEHEAKLVFKQVVASIKHLHDQGIVHRDIKDENVIVDSH-GF-VKLIDFGSA-AYIKSGPFDVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLYTI</Hsp_hseq>
      <Hsp_midline>KL D +E   D   I   V G     +LF+ I  +  + E +  L  +Q+   + ++H Q I+H D+K EN++  S  G+ +K+IDFG A  Y       V  GT ++ APEV+    +   P D+W++GV+ Y +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>2.38272e-09</Hsp_evalue>
      <Hsp_query-from>1264</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>95</Hsp_hit-from>
      <Hsp_hit-to>206</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>118</Hsp_align-len>
      <Hsp_qseq>DITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPEV-VNYEFVSFPTDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>DIYFVTE-LQGTDL-HRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILI--NENCDLKICDFGLARIQDPQMTGYVS--TRYYRAPEIMLTWQKYDVEVDIWSAGCI</Hsp_hseq>
      <Hsp_midline>DI  + E ++G +L +R++    L +     F+ QI  G+ Y+H   ++H DLKP NIL        +KI DFGLAR   P+    VS  T  + APE+ + ++      D+WS G I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>2.81263e-09</Hsp_evalue>
      <Hsp_query-from>1237</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>559</Hsp_hit-from>
      <Hsp_hit-to>710</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>155</Hsp_align-len>
      <Hsp_qseq>LFDAYESRSDITLIMEYVEGGELFNRIIDQSG--LSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKV----------------------SF-GTSEFLAPEVVNYEFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>LYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENIL-LHQSGH-IMLSDFDLSIQAK-DSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEM</Hsp_hseq>
      <Hsp_midline>L+ +++S   + L MEY  GGE F  +  +    + E D   +  ++   + Y+H    ++ DLKPENIL L + G+ I + DF L+ + K   K+ V                      SF GT E++APEV+     +   D W++G++ Y +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>2.98353e-09</Hsp_evalue>
      <Hsp_query-from>1258</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>1105</Hsp_hit-from>
      <Hsp_hit-to>1241</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>140</Hsp_align-len>
      <Hsp_qseq>RSDITLIMEYVEGGELFNRIIDQSGL-SELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRY---KPR--------------EKLKVSFGTSEFLAPEVVNYEFVS---FPTDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>RDKVNIFMEYCEGGSLAS-LLDHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILL--DFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCV</Hsp_hseq>
      <Hsp_midline>R  + + MEY EGG L + ++D   +  E+ T ++  ++ EG+ Y+HQ  ++H D+KPENIL    +   IK +DFG AR     + R              + L    GT  ++APE ++   V       D+W++G +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YIL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:287790:288908:-1 gene:YIL035C transcript:YIL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA1 description:Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000001297]</Hit_def>
  <Hit_accession>YIL035C</Hit_accession>
  <Hit_len>372</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>3.74873e-09</Hsp_evalue>
      <Hsp_query-from>1273</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>150</Hsp_hit-from>
      <Hsp_hit-to>260</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>115</Hsp_align-len>
      <Hsp_qseq>LIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPE-VVNYEFVSFPTDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>LVFEYVDNVDF--RIL-YPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHK-NKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTM</Hsp_hseq>
      <Hsp_midline>L+ EYV+  +   RI+    L++L+   ++ ++ + + Y H   I+H D+KP N++   +   ++++ID+GLA  Y    +  V   +  F  PE +V+Y    +  D+WS G +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YDL025C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:405344:407206:-1 gene:YDL025C transcript:YDL025C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RTK1 description:Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002183]</Hit_def>
  <Hit_accession>YDL025C</Hit_accession>
  <Hit_len>620</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>4.85979e-09</Hsp_evalue>
      <Hsp_query-from>1273</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>384</Hsp_hit-from>
      <Hsp_hit-to>503</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>125</Hsp_align-len>
      <Hsp_qseq>LIMEYVEGGELFNRIIDQSGLSELDTV-LFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYK-PREKLKVS----FGTSEFLAPEVV-NYEFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>LVMEYAPY-DFFNLVM--SNLMTQDEVNCYFKQLCHGVNYLHSMGLAHRDLKLDN--CVVTKDGILKLIDFGSAVVFQYPYEDTIVKSHGIVGSDPYLAPELLKQTSYDPRVADVWSIAIIFYCM</Hsp_hseq>
      <Hsp_midline>L+MEY    + FN ++  S L   D V  + +Q+C GV+Y+H   + H DLK +N  C+      +K+IDFG A  ++ P E   V      G+  +LAPE++    +     D+WS+ +I Y +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>6.05618e-09</Hsp_evalue>
      <Hsp_query-from>1273</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>305</Hsp_hit-from>
      <Hsp_hit-to>438</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>138</Hsp_align-len>
      <Hsp_qseq>LIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICE---GVHYMHQQYILHLDLKPENILCLSRWGYQ----------------IKIIDFGLARRYKPREKLKVSFGTSEFLAPEVV-NYEFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>MIMSYCPAGDLLAAVMARNG--RLEAWLIQRIFTEVVLAVKYLHENSIIHRDLKLENILL--KYSFDDINSFRDSPIYCKQNFIELADFGLCKKIENNEMCTARCGSEDYVSPEILMGVPYDGHLSDTWALGVILYSL</Hsp_hseq>
      <Hsp_midline>+IM Y   G+L   ++ ++G   L+  L  R   E    V Y+H+  I+H DLK ENIL   ++ +                 I++ DFGL ++ +  E      G+ ++++PE++    +    +D W++GVI Y L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>8.3135e-09</Hsp_evalue>
      <Hsp_query-from>1357</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>133</Hsp_hit-from>
      <Hsp_hit-to>222</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>92</Hsp_align-len>
      <Hsp_qseq>FVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSF-----GTSEFLAPEV-VNYEFVSFPTDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>FIYQILCALKYIHSANVLHCDLKPKNLLVNS--DCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCI</Hsp_hseq>
      <Hsp_midline>F+ QI   + Y+H   +LH DLKP+N+L  S    Q+KI +FGL+  Y    K+   F      +  + APE+ +NY+  +   D+WS G I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>9.07444e-09</Hsp_evalue>
      <Hsp_query-from>1357</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>116</Hsp_hit-from>
      <Hsp_hit-to>201</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>88</Hsp_align-len>
      <Hsp_qseq>FVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYK-PREKLKVSFGTSEFLAPEV-VNYEFVSFPTDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>FMMQLCKGIAYCHSHRILHRDLKPQNLL-INKDG-NLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCI</Hsp_hseq>
      <Hsp_midline>F+ Q+C+G+ Y H   ILH DLKP+N+L +++ G  +K+ DFGLAR +  P         T  + APEV +  +  S   D WS+G I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>9.82486e-09</Hsp_evalue>
      <Hsp_query-from>1237</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>65</Hsp_hit-from>
      <Hsp_hit-to>215</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>155</Hsp_align-len>
      <Hsp_qseq>LFDAYESRSDITLIMEYVEGGELFNRI-IDQS-------GLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPEVV-----------NYEFVSFP------TDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>MLDFYTDDSYYIMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQIDMQKIIKQLCSAISFAHSLGIAHRDIKPENIL-LTING-DIKLADWGHAIQSPKSNDFQI--GTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYL</Hsp_hseq>
      <Hsp_midline>+ D Y   S   +++EY E G+L++ + I +S        L ++D    ++Q+C  + + H   I H D+KPENIL L+  G  IK+ D+G A +       ++  GT  + APE             N++  S P       D WS+G   + L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>1.38954e-08</Hsp_evalue>
      <Hsp_query-from>1357</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>133</Hsp_hit-from>
      <Hsp_hit-to>222</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>92</Hsp_align-len>
      <Hsp_qseq>FVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRY--KPREK---LKVSFGTSEFLAPEV-VNYEFVSFPTDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>FTYQILCGLKYIHSADVLHRDLKPGNLLVNADC--QLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCI</Hsp_hseq>
      <Hsp_midline>F  QI  G+ Y+H   +LH DLKP N+L  +    Q+KI DFGLAR Y   P E    L     T  + APE+ ++Y+  +   D+WS G I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>1.65931e-08</Hsp_evalue>
      <Hsp_query-from>1270</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>121</Hsp_hit-from>
      <Hsp_hit-to>238</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>119</Hsp_align-len>
      <Hsp_qseq>TLIMEYVE---GGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPE-VVNYEFVSFPTDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>NFVMEYIPQTLSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGIA-KVCDFGSAQRLDDNTELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCI</Hsp_hseq>
      <Hsp_midline>  +MEY+      E+     + S +      L+  QI   +  +H   I H DLKP NIL +   G   K+ DFG A+R     +LK  F +  + APE ++N +  +   D+WS+G I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>1.69045e-08</Hsp_evalue>
      <Hsp_query-from>1246</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>1245</Hsp_hit-from>
      <Hsp_hit-to>1369</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>127</Hsp_align-len>
      <Hsp_qseq>AYESRSDI-TLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKP--REKLKVSFGTSEFLAPEVVNY-EFVSFPTDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>GFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLL-LDQDGI-CKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCI</Hsp_hseq>
      <Hsp_midline> +E++++I +L +EYV GG + + I       E        Q+ +G+ Y+H + ILH D+K +N+L L + G   KI DFG++R+ K           GT  ++APE+V+  +  S   D+WS+G I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>2.17146e-08</Hsp_evalue>
      <Hsp_query-from>1258</Hsp_query-from>
      <Hsp_query-to>1497</Hsp_query-to>
      <Hsp_hit-from>1337</Hsp_hit-from>
      <Hsp_hit-to>1414</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>80</Hsp_align-len>
      <Hsp_qseq>RSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARR</Hsp_qseq>
      <Hsp_hseq>RDKVNIFMEYCEGGSLAALLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILL--DFNGVIKYVDFGAAKK</Hsp_hseq>
      <Hsp_midline>R  + + MEY EGG L   +       E+ T ++  Q+ EG+ Y+H+  I+H D+KPENIL    +   IK +DFG A++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>2.25424e-08</Hsp_evalue>
      <Hsp_query-from>1360</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>174</Hsp_hit-from>
      <Hsp_hit-to>274</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>101</Hsp_align-len>
      <Hsp_qseq>VRQICEGVHYMHQQYILHLDLKPENILC-----------LSRWGYQ----IKIIDFGLARRYKPREKLKVSFGTSEFLAPEV-VNYEFVSFPTDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>LSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVENKNPYTAYVSTRWYRSPEILLRSGYYSKPLDIWAFGCV</Hsp_hseq>
      <Hsp_midline>+ QI  G+ ++H+    H DLKPENIL            +++ GYQ    IK+ DFGLAR  + +        T  + +PE+ +   + S P D+W+ G +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>3.06644e-08</Hsp_evalue>
      <Hsp_query-from>1231</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>114</Hsp_hit-from>
      <Hsp_hit-to>269</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>158</Hsp_align-len>
      <Hsp_qseq>EKLFDAYESRSD-----ITLIMEYVEGG--------ELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRY--------KPREKLKVS--FGTSEFLAPEVVNYE---FVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>ENVVELYEILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNG--TVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCL</Hsp_hseq>
      <Hsp_midline>E + + YE  +D     + L++EY   G        ++  + +  S L+   +   V  +  G+ Y+H Q I H D+KP N+L  S     +KI DFG+A              E+L  S   GT  F APE+ + E     S   D+WS+GV  Y L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>3.49877e-08</Hsp_evalue>
      <Hsp_query-from>1264</Hsp_query-from>
      <Hsp_query-to>1608</Hsp_query-to>
      <Hsp_hit-from>94</Hsp_hit-from>
      <Hsp_hit-to>205</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>117</Hsp_align-len>
      <Hsp_qseq>DITLIMEYVEGGELFNRIIDQS--GLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPEVVNYEFVSFPTDMWSVG</Hsp_qseq>
      <Hsp_hseq>ELYILLEYCANGSL-RRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSA--DNTVKLADFGVSTIVN-SSALTLA-GTLNWMAPEILGNRGASTLSDIWSLG</Hsp_hseq>
      <Hsp_midline>++ +++EY   G L  R+I +S  GLSE ++  +V Q   G+ Y+H + ++H D+K  NIL  +     +K+ DFG++        L ++ GT  ++APE++     S  +D+WS+G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>4.26601e-08</Hsp_evalue>
      <Hsp_query-from>1246</Hsp_query-from>
      <Hsp_query-to>1620</Hsp_query-to>
      <Hsp_hit-from>777</Hsp_hit-from>
      <Hsp_hit-to>916</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>AYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVL-FVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYK---------------PREKLKVSFGTSEFLAPEVVN-YEFVSFPTDMWSVGVITY</Hsp_qseq>
      <Hsp_hseq>AVKKKSTLFIQMEYCENRTLYDLIHSENLNQQRDEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDE--SRNVKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVLDGTGHYNEKIDMYSLGIIFF</Hsp_hseq>
      <Hsp_midline>A + +S + + MEY E   L++ I  ++   + D      RQI E + Y+H Q I+H DLKP NI         +KI DFGLA+                    + L  + GT+ ++A EV++     +   DM+S+G+I +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>6.93478e-08</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>434</Hsp_hit-from>
      <Hsp_hit-to>559</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>131</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVL---FVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFL-APEVVNYEFVSFPTDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>RMYDSFVHKNHLCLVFELLSNN--LYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPELKIIDFGSSCE---EARTVYTYIQSRFYRAPEIILGIPYSTSIDMWSLGCI</Hsp_hseq>
      <Hsp_midline>+++D++  ++ + L+ E +        ++ Q+    L   L   F  QI + +  + +  ++H DLKPENIL  +    ++KIIDFG +       +   ++  S F  APE++     S   DMWS+G I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>7.57677e-08</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1620</Hsp_query-to>
      <Hsp_hit-from>84</Hsp_hit-from>
      <Hsp_hit-to>211</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>132</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPRE-KLKVSFGTSEFLAPEVVNYEFVSFPT--DMWSVGVITY</Hsp_qseq>
      <Hsp_hseq>RYYGSYLKDTSLWIIMEHCAGGSL-RSLLRPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEG--NVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVI-MEGVYYDTKVDIWSLGITTY</Hsp_hseq>
      <Hsp_midline>+ + +Y   + + +IME+  GG L   ++    + E    + +R++   +  +H+  ++H D+K  N+L  +     +K+ DFG+A +      + +   GT  ++APEV+  E V + T  D+WS+G+ TY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>71</Hit_num>
  <Hit_id>YNL183C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:293137:295509:-1 gene:YNL183C transcript:YNL183C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NPR1 description:Protein kinase; stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p; negatively regulates Ldb19p-mediated endocytosis through phosphorylation of Ldb19p, which prevents its association with the plasma membrane; Npr1p activity is negatively regulated via phosphorylation by the TOR complex; NPR1 has a paralog, PRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005127]</Hit_def>
  <Hit_accession>YNL183C</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>1.05917e-07</Hsp_evalue>
      <Hsp_query-from>1267</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>513</Hsp_hit-from>
      <Hsp_hit-to>630</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>122</Hsp_align-len>
      <Hsp_qseq>ITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYK-PREKLKVS----FGTSEFLAPEVVNY-EFVSFPTDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>ILQVMEYCEY-DLF-AIVMSNKMSYEEICCCFKQILTGVQYLHSIGLAHRDLKLDN--CVINEKGIVKLIDFGAAVVFSYPFSKNLVEASGIVGSDPYLAPEVCIFAKYDPRPVDIWSSAII</Hsp_hseq>
      <Hsp_midline>I  +MEY E  +LF  I+  + +S  +     +QI  GV Y+H   + H DLK +N  C+      +K+IDFG A  +  P  K  V      G+  +LAPEV  + ++   P D+WS  +I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>72</Hit_num>
  <Hit_id>YNL020C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:595623:597539:-1 gene:YNL020C transcript:YNL020C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ARK1 description:Serine/threonine protein kinase; involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis; ARK1 has a paralog, PRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004965]</Hit_def>
  <Hit_accession>YNL020C</Hit_accession>
  <Hit_len>638</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>1.24215e-07</Hsp_evalue>
      <Hsp_query-from>1264</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>104</Hsp_hit-from>
      <Hsp_hit-to>239</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>141</Hsp_align-len>
      <Hsp_qseq>DITLIMEYVEGGEL--FNRIIDQSGLSELDTVLFVRQICEGVHYMH--QQYILHLDLKPENILCLSRWGYQIKIIDF----GLARRYKPREKLKVSF--------GTSEFLAPEVVNYEFVSFP----TDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>EVFVLMEYCERGGLIDFMNTRLQNRLHEFEILQIMSQVTQGVAAMHALQPPLIHRDIKIENVLISANNEY--KLCDFGSVCGIIR--PPRNSQELSYVQQDILKNTTAQYRSPEMID-TFRGLPIDEKSDIWALGIFLYKL</Hsp_hseq>
      <Hsp_midline>++ ++MEY E G L  F     Q+ L E + +  + Q+ +GV  MH  Q  ++H D+K EN+L  +   Y  K+ DF    G+ R   PR   ++S+         T+++ +PE+++  F   P    +D+W++G+  Y L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>73</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>1.69556e-07</Hsp_evalue>
      <Hsp_query-from>1252</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>251</Hsp_hit-from>
      <Hsp_hit-to>370</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>128</Hsp_align-len>
      <Hsp_qseq>ESRSDITLIMEYVEG---GELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPEVV----NYEFVSFPTDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>ESQKTVYMIFEYADNDLSGLLLNKEVQ---ISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGN--LKITDFGLARKMNSRADYTNRVITLWYRPPELLLGTTNY---GTEVDMWGCGCL</Hsp_hseq>
      <Hsp_midline>ES+  + +I EY +    G L N+ +    +S        +Q+  G+ Y+H   ILH D+K  NIL  ++    +KI DFGLAR+   R        T  +  PE++    NY       DMW  G +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>74</Hit_num>
  <Hit_id>YDL214C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:74446:76545:-1 gene:YDL214C transcript:YDL214C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR2 description:Serine/threonine protein kinase; inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance; PRR2 has a paralog, NPR1, that arose from the whole genome duplication [Source:SGD;Acc:S000002373]</Hit_def>
  <Hit_accession>YDL214C</Hit_accession>
  <Hit_len>699</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>1.77521e-07</Hsp_evalue>
      <Hsp_query-from>1180</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>408</Hsp_hit-from>
      <Hsp_hit-to>557</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>155</Hsp_align-len>
      <Hsp_qseq>IIGLTLAAKVIRVKSPKEKLFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYK-PREKLKVS----FGTSEFLAPEVVNY-EFVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>IISEYCIASTLKNPNICETLEILYE-KGKIFQILEYCEY-DLFSLVMSEKMHYEEICCLF-KQLINGVKYLHDIGLSHRDLKLDNCV-VTRRGI-LKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFYFNEYDPRALDVWSVGIIFFCM</Hsp_hseq>
      <Hsp_midline>II     A  ++  +  E L   YE +  I  I+EY E  +LF+ ++ +    E    LF +Q+  GV Y+H   + H DLK +N + ++R G  +K+IDFG +  +  P     +      G+  +L+PEV  + E+     D+WSVG+I + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>75</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>2.3353e-07</Hsp_evalue>
      <Hsp_query-from>1333</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>138</Hsp_hit-from>
      <Hsp_hit-to>239</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>53</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>104</Hsp_align-len>
      <Hsp_qseq>LSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLAR-----RYKPREKLKVSF----GTSEFLAPE-VVNYEFVSFPTDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>LSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGC--LKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCI</Hsp_hseq>
      <Hsp_midline>LSE     F+ QI  G+ Y+H   ++H DLKP NILC       +KI DFGLAR      +K    ++        T  + APE +++ +  S   D+W+VG I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>76</Hit_num>
  <Hit_id>YPL026C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:500675:502183:-1 gene:YPL026C transcript:YPL026C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKS1 description:Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway; SKS1 has a paralog, VHS1, that arose from the whole genome duplication [Source:SGD;Acc:S000005947]</Hit_def>
  <Hit_accession>YPL026C</Hit_accession>
  <Hit_len>502</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>3.29638e-07</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>124</Hsp_hit-from>
      <Hsp_hit-to>264</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>145</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVL--FVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPEVVNYEF-------------VSFPT---DMWSVGVI</Hsp_qseq>
      <Hsp_hseq>KIHQVLESSIATFIVMDYYDR-DLFTSIVDDKHFVNHGILIKKVFLQLCSALDHCHRLGIYHCDIKPENVL-LDR-NDNAYLCDFGLSTKSKYLAP-NVCVGSSYYMAPERILYCLNTTTNGIHVDECCSSLPTDTGDIWSLGII</Hsp_hseq>
      <Hsp_midline>K+    ES     ++M+Y +  +LF  I+D         ++     Q+C  + + H+  I H D+KPEN+L L R      + DFGL+ + K      V  G+S ++APE + Y                S PT   D+WS+G+I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>77</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>5.05117e-07</Hsp_evalue>
      <Hsp_query-from>1267</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>110</Hsp_hit-from>
      <Hsp_hit-to>229</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>126</Hsp_align-len>
      <Hsp_qseq>ITLIMEYVEGGELFNR----IIDQSGLSELDTVLFVRQICEGVHYMHQ-QYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFL-APEVV----NYEFVSFPTDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>LNLILEYMPQS-LYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLL-VDPETWSLKLCDFGSAKQLKPTEP-NVSYICSRYYRAPELIFGATNY---TNQIDIWSSGCV</Hsp_hseq>
      <Hsp_midline>+ LI+EY+    L+ R    +  ++ +S L+   ++ Q+ + ++Y+H    + H D+KP+N+L +    + +K+ DFG A++ KP E   VS+  S +  APE++    NY   +   D+WS G +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>78</Hit_num>
  <Hit_id>YDR247W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:956013:957398:1 gene:YDR247W transcript:YDR247W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VHS1 description:Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; VHS1 has a paralog, SKS1, that arose from the whole genome duplication [Source:SGD;Acc:S000002655]</Hit_def>
  <Hit_accession>YDR247W</Hit_accession>
  <Hit_len>461</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>5.68979e-07</Hsp_evalue>
      <Hsp_query-from>1273</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>136</Hsp_hit-from>
      <Hsp_hit-to>263</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>134</Hsp_align-len>
      <Hsp_qseq>LIMEYVEGGELFNRIIDQSGLSELDTVLFVR----QICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPEVVNYE----------------FVSFPTDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>IVMDYYPT-DLFTSIVDNRHF--VTNGLLVKKVFLQICSALNYCHEHGIYHCDIKPENLLLDTEDN--VFLCDFGLSTT-STYIKPNVCIGSSYYMPPERISFDGRVSSSKSGGHKLGKVCPSCNGDLWSLGII</Hsp_hseq>
      <Hsp_midline>++M+Y    +LF  I+D      +   L V+    QIC  ++Y H+  I H D+KPEN+L  +     + + DFGL+       K  V  G+S ++ PE ++++                  S   D+WS+G+I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>79</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>7.4121e-07</Hsp_evalue>
      <Hsp_query-from>1243</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>81</Hsp_hit-from>
      <Hsp_hit-to>212</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>DAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLAR-----RYKPREKLKVSFGTSEFL------APEV-VNYEFVSFPTDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>DSFENFNEVYIIQELMQTD--LHRVISTQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINS--NCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCI</Hsp_hseq>
      <Hsp_midline>D++E+ +++ +I E ++     +R+I    LS+     F+ Q    V  +H   ++H DLKP N+L  S     +K+ DFGLAR          E      G +E++      APEV +     S   D+WS G I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>80</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>8.00732e-07</Hsp_evalue>
      <Hsp_query-from>1366</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>269</Hsp_hit-from>
      <Hsp_hit-to>354</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>90</Hsp_align-len>
      <Hsp_qseq>QICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFG------TSEFLAPE-VVNYEFVSFPTDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>QLLDGVSYLHQNWVLHRDLKPANIMVTIDGC--VKIGDLGLARKF--HNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCI</Hsp_hseq>
      <Hsp_midline>Q+ +GV Y+HQ ++LH DLKP NI+        +KI D GLAR++     L+  +       T  + APE ++     +   D+WSVG I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>81</Hit_num>
  <Hit_id>YDL028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:400997:403291:-1 gene:YDL028C transcript:YDL028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MPS1 description:Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]</Hit_def>
  <Hit_accession>YDL028C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>9.01522e-07</Hsp_evalue>
      <Hsp_query-from>1273</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>514</Hsp_hit-from>
      <Hsp_hit-to>647</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>140</Hsp_align-len>
      <Hsp_qseq>LIMEYVEGGELFNRIIDQSGLSELD---TVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKV----SFGTSEFLAPEVV---NYE------------FVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>LIMEC--GDHDLSQILNQRSGMPLDFNFVRFYTKEMLLCIKVVHDAGIVHSDLKPANFVLVKGI---LKIIDFGIANAV-PEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQM</Hsp_hseq>
      <Hsp_midline>LIME   G    ++I++Q     LD      + +++   +  +H   I+H DLKP N + +      +KIIDFG+A    P   + +      GT  ++APE +   NY              V  P+DMWS G I Y +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>82</Hit_num>
  <Hit_id>YPR111W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:747306:749000:1 gene:YPR111W transcript:YPR111W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF20 description:Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006315]</Hit_def>
  <Hit_accession>YPR111W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>1.14091e-06</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1584</Hsp_query-to>
      <Hsp_hit-from>231</Hsp_hit-from>
      <Hsp_hit-to>341</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>117</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPEVVNYEFVSF</Hsp_qseq>
      <Hsp_hseq>KLLYAFQDPESLYLAMEFVPGGDFRTLLINTRILKSGHARFYISEMFCAVNALHELGYTHRDLKPENFL-IDATGH-IKLTDFGLAAGTVSNERIE----SMKIRLEEVKNLEFPAF</Hsp_hseq>
      <Hsp_midline>KL  A++    + L ME+V GG+    +I+   L       ++ ++   V+ +H+    H DLKPEN L +   G+ IK+ DFGLA      E+++    + +    EV N EF +F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>83</Hit_num>
  <Hit_id>YOR267C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:822588:824867:-1 gene:YOR267C transcript:YOR267C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRK1 description:Protein kinase; implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005793]</Hit_def>
  <Hit_accession>YOR267C</Hit_accession>
  <Hit_len>759</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>1.17476e-06</Hsp_evalue>
      <Hsp_query-from>1276</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>295</Hsp_hit-from>
      <Hsp_hit-to>410</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>120</Hsp_align-len>
      <Hsp_qseq>IMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLAR--RYKPREKLKVSF---GTSEFLAPEVVNYEFVSFP--TDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>VMEYCPID--FFAVVMTGKMSRGEINCCLKQLTEGVKYLHSMGLAHRDLKLDNCVMTSQG--ILKLIDFGSAVVFRYPFEDGVTMAHGIVGSDPYLAPEVITSTKSYDPQCVDIWSIGII</Hsp_hseq>
      <Hsp_midline>+MEY      F  ++    +S  +    ++Q+ EGV Y+H   + H DLK +N +  S+    +K+IDFG A   RY   + + ++    G+  +LAPEV+       P   D+WS+G+I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>84</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>1.32179e-06</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>209</Hsp_hit-from>
      <Hsp_hit-to>372</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>167</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGGE--------LFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLA-----------RRYKPREKLKVSFGTSEFLAPEVVNYE-----------------FVSFPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>EVLDDLKSRK-IYLVLEYCSRGEVKWCPPDCMESDAKGPSLLSFQETREILRGVVLGLEYLHYQGIIHRDIKPANLL-ISGDG-TVKISDFGVSLAASSTNSSDSSESLDELELAKTVGTPAFFAPEMCLGEDAFTRYNLTKENLFRGSCISFMIDIWAVGVTLYCL</Hsp_hseq>
      <Hsp_midline>++ D  +SR  I L++EY   GE        + +     S LS  +T   +R +  G+ Y+H Q I+H D+KP N+L +S  G  +KI DFG++                  +L  + GT  F APE+   E                  +SF  D+W+VGV  Y L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>85</Hit_num>
  <Hit_id>YOR061W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:441534:442553:1 gene:YOR061W transcript:YOR061W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA2 description:Alpha&apos; catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000005587]</Hit_def>
  <Hit_accession>YOR061W</Hit_accession>
  <Hit_len>339</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>1.49024e-06</Hsp_evalue>
      <Hsp_query-from>1345</Hsp_query-from>
      <Hsp_query-to>1614</Hsp_query-to>
      <Hsp_hit-from>143</Hsp_hit-from>
      <Hsp_hit-to>232</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>91</Hsp_align-len>
      <Hsp_qseq>DTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFGTSEFLAPE-VVNYEFVSFPTDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>DIQYYFTQLLIALDYCHSMGIMHRDVKPQNVM-IDPTERKLRLIDWGLAEFYHPGVDYNVRVASRYHKGPELLVNLNQYDYSLDLWSVGCM</Hsp_hseq>
      <Hsp_midline>D   +  Q+   + Y H   I+H D+KP+N++ +     ++++ID+GLA  Y P     V   +     PE +VN     +  D+WSVG +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>86</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>1.70975e-06</Hsp_evalue>
      <Hsp_query-from>1234</Hsp_query-from>
      <Hsp_query-to>1491</Hsp_query-to>
      <Hsp_hit-from>239</Hsp_hit-from>
      <Hsp_hit-to>322</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>44</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>86</Hsp_align-len>
      <Hsp_qseq>KLFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLA</Hsp_qseq>
      <Hsp_hseq>KLLYAFQDLQSLYLAMEFVPGGDFRTLLINTRCLKSGHARFYISEMFCAVNALHDLGYTHRDLKPENFLIDAKG--HIKLTDFGLA</Hsp_hseq>
      <Hsp_midline>KL  A++    + L ME+V GG+    +I+   L       ++ ++   V+ +H     H DLKPEN L  ++    IK+ DFGLA</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>87</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>2.65735e-06</Hsp_evalue>
      <Hsp_query-from>1237</Hsp_query-from>
      <Hsp_query-to>1491</Hsp_query-to>
      <Hsp_hit-from>415</Hsp_hit-from>
      <Hsp_hit-to>497</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>26</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>85</Hsp_align-len>
      <Hsp_qseq>LFDAYESRSDITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLA</Hsp_qseq>
      <Hsp_hseq>LYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIRG--HIKLSDFGLS</Hsp_hseq>
      <Hsp_midline>L+ +++    + LIME++ GG+L   +I     +E  T  ++ +    +  +H+   +H D+KP+NIL   R    IK+ DFGL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>88</Hit_num>
  <Hit_id>YKL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:347214:349136:-1 gene:YKL048C transcript:YKL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ELM1 description:Serine/threonine protein kinase; regulates the orientation checkpoint, the morphogenesis checkpoint and the metabolic switch from fermentative to oxidative metabolism by phosphorylating the activation loop of Kin4p, Hsl1p and Snf4p respectively; cooperates with Hsl7p in recruiting Hsl1p to the septin ring, a prerequisite for subsequent recruitment, phosphorylation, and degradation of Swe1p; forms part of the bud neck ring; regulates cytokinesis [Source:SGD;Acc:S000001531]</Hit_def>
  <Hit_accession>YKL048C</Hit_accession>
  <Hit_len>640</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>3.79727e-06</Hsp_evalue>
      <Hsp_query-from>1333</Hsp_query-from>
      <Hsp_query-to>1626</Hsp_query-to>
      <Hsp_hit-from>227</Hsp_hit-from>
      <Hsp_hit-to>347</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>123</Hsp_align-len>
      <Hsp_qseq>LSELDTVLFVRQICE----GVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPRE--------------KLKVSFGTSEFLAPEVVNY-----EFVS--FPTDMWSVGVITYML</Hsp_qseq>
      <Hsp_hseq>ISNCSVSTFAKKILEDMTKGLEYLHSQGCIHRDIKPSNIL-LDEEEKVAKLSDFG-SCIFTPQSLPFSDANFEDCFQRELNKIVGTPAFIAPELCHLGNSKRDFVTDGFKLDIWSLGVTLYCL</Hsp_hseq>
      <Hsp_midline>+S      F ++I E    G+ Y+H Q  +H D+KP NIL L       K+ DFG +  + P+               +L    GT  F+APE+ +      +FV+  F  D+WS+GV  Y L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>1029856483</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058725-RA transcript Note:&quot;Similar to Wfs1 Wolframin (Mus musculus)&quot; offset:0 AED:0.27 eAED:0.29 QI:0|0|0|0.8|1|1|10|0|530</Iteration_query-def>
  <Iteration_query-len>1593</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>1002332479</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0044042-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.99 eAED:1.00 QI:0|0|0|0.2|0.75|0.6|5|1004|177</Iteration_query-def>
  <Iteration_query-len>1538</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>958752806</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058731-RA transcript Note:&quot;Similar to LSM14A Protein LSM14 homolog A (Pongo abelii)&quot; offset:164 AED:0.03 eAED:0.03 QI:164|0.87|1|1|1|1|9|3590|443</Iteration_query-def>
  <Iteration_query-len>5086</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YPR129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:792687:793736:1 gene:YPR129W transcript:YPR129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCD6 description:Repressor of translation initiation; binds eIF4G through its RGG domain and inhibits recruitment of the preinitiation complex; also contains an Lsm domain; may have a role in RNA processing; overproduction suppresses null mutation in clathrin heavy chain gene CHC1; forms cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000006333]</Hit_def>
  <Hit_accession>YPR129W</Hit_accession>
  <Hit_len>349</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>2.20348e-11</Hsp_evalue>
      <Hsp_query-from>183</Hsp_query-from>
      <Hsp_query-to>395</Hsp_query-to>
      <Hsp_hit-from>4</Hsp_hit-from>
      <Hsp_hit-to>76</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>73</Hsp_align-len>
      <Hsp_qseq>YIGSKISLISKAEIRYEGILYTIDTENSTVALAKVRSFGTEDRPTERP--VAPRDEIFEYIVFRGSDIKDITV</Hsp_qseq>
      <Hsp_hseq>YIGKTISLISVTDNRYVGLLEDIDSEKGTVTLKEVRCFGTEGRKNWGPEEIYPNPTVYNSVKFNGSEVKDLSI</Hsp_hseq>
      <Hsp_midline>YIG  ISLIS  + RY G+L  ID+E  TV L +VR FGTE R    P  + P   ++  + F GS++KD+++</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>5.73791e-06</Hsp_evalue>
      <Hsp_query-from>1002</Hsp_query-from>
      <Hsp_query-to>1277</Hsp_query-to>
      <Hsp_hit-from>204</Hsp_hit-from>
      <Hsp_hit-to>277</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>92</Hsp_align-len>
      <Hsp_qseq>DFDFESANAQFNKEELEKEFQDKLKLKDDRGGEKVVNGEDKESGAETQSHEDDSAYYDKTKSFFDNISRESDPRERRSTWAEERRMNVETFG</Hsp_qseq>
      <Hsp_hseq>DFDFQSNNAKFTK-------GDSTDVEKEKELESAVHKQD----------ESDEQFYNKKSSFFDTISTSTETNTNMR-WQEEKMLNVDTFG</Hsp_hseq>
      <Hsp_midline>DFDF+S NA+F K        D   ++ ++  E  V+ +D          E D  +Y+K  SFFD IS  ++       W EE+ +NV+TFG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3556953064</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058735-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.46 eAED:0.66 QI:0|0|0|1|1|1|3|0|101</Iteration_query-def>
  <Iteration_query-len>306</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>72</Statistics_hsp-len>
      <Statistics_eff-space>73166010</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058726-RA transcript Note:&quot;Similar to SLC9A3 Sodium/hydrogen exchanger 3 (Homo sapiens)&quot; offset:0 AED:0.25 eAED:0.25 QI:0|0|0|0.69|1|1|13|0|529</Iteration_query-def>
  <Iteration_query-len>1590</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDR456W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1367485:1369386:1 gene:YDR456W transcript:YDR456W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NHX1 description:Na+/H+ and K+/H+ exchanger; required for intracellular sequestration of Na+ and K+; located in the vacuole and late endosome compartments; required for osmotolerance to acute hypertonic shock and for vacuolar fusion; ortholog of human NHE9, which is linked to autism [Source:SGD;Acc:S000002864]</Hit_def>
  <Hit_accession>YDR456W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.6481</Hsp_bit-score>
      <Hsp_score>200</Hsp_score>
      <Hsp_evalue>7.85882e-17</Hsp_evalue>
      <Hsp_query-from>265</Hsp_query-from>
      <Hsp_query-to>1038</Hsp_query-to>
      <Hsp_hit-from>119</Hsp_hit-from>
      <Hsp_hit-to>448</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>89</Hsp_identity>
      <Hsp_positive>145</Hsp_positive>
      <Hsp_gaps>74</Hsp_gaps>
      <Hsp_align-len>331</Hsp_align-len>
      <Hsp_qseq>TLTPTVFFFYLLPPIVLDAGYFMPARLFFDNIGAILMYAVLGTVWNAATTGLSLY----------GIFLTGAMGEGREV---------------HVNEVLFIIVFGESLLNDAVTVVLYKVFDSF---VALGGENIEG---------VDYIKXXXXXXXXXXXXXXTRFTKHVKMIEPGFVFLLSYLAYLTAEMFTLSAILA------------------KSQTVIKYTMKMLASAAETIIFIFLGISAVDTEKWTWNTAFILPTLIFVSVYRIIGVVIQTWILNW-FRV---------------VPLS-PIDQAVMSY-GGLRGAVAFAL</Hsp_qseq>
      <Hsp_hseq>TFNSSYFFNVLLPPIILNSGYELNQVNFFNNMLSILIFAIPGTFISAVVIGIILYIWTFLGLESIDISFADAMSVGATLSATDPVTILSIFNAYKVDPKLYTIIFGESLLNDAISIVMFETCQKFHGQPATFSSVFEGAGLFLMTFSVSLLIGVLIGILVALLLKHTHIRRYPQ-IESCLILLIAYESYFFSNGCHMSGIVSLLFCGITLKHYAYYNMSRRSQITIKYIFQLLARLSENFIFIYLGLELFTEVELVYKPLLIIVAAISICVARWCAVFPLSQFVNWIYRVKTIRSMSGITGENISVPDEIPYNYQMMTFWAGLRGAVGVAL</Hsp_hseq>
      <Hsp_midline>T   + FF  LLPPI+L++GY +    FF+N+ +IL++A+ GT  +A   G+ LY           I    AM  G  +                V+  L+ I+FGESLLNDA+++V+++    F    A      EG         V  + G++  I   ++   T   ++ + IE   + L++Y +Y  +    +S I++                  +SQ  IKY  ++LA  +E  IFI+LG+      +  +    I+   I + V R   V   +  +NW +RV               VP   P +  +M++  GLRGAV  AL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>1000038812</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0038123-RA transcript Note:&quot;Similar to Tppp Tubulin polymerization-promoting protein (Rattus norvegicus)&quot; offset:5 AED:0.47 eAED:0.47 QI:5|0|0|0.33|0|0|3|1|114</Iteration_query-def>
  <Iteration_query-len>348</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>77</Statistics_hsp-len>
      <Statistics_eff-space>93828813</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058727-RA transcript Note:&quot;Similar to CHD7 Chromodomain-helicase-DNA-binding protein 7 (Homo sapiens)&quot; offset:0 AED:0.26 eAED:0.32 QI:0|0|0|0.78|1|1|28|0|2265</Iteration_query-def>
  <Iteration_query-len>6798</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YER164W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:505392:509798:1 gene:YER164W transcript:YER164W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHD1 description:Chromatin remodeler that regulates various aspects of transcription; acts in in conjunction with Isw1b to regulate chromatin structure and maintain chromatin integrity during transcription elongation by RNAP II by preventing trans-histone exchange over coding regions; contains a chromo domain, a helicase domain and a DNA-binding domain; component of both the SAGA and SLIK complexes [Source:SGD;Acc:S000000966]</Hit_def>
  <Hit_accession>YER164W</Hit_accession>
  <Hit_len>1468</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>367.466</Hsp_bit-score>
      <Hsp_score>942</Hsp_score>
      <Hsp_evalue>3.43424e-104</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>1596</Hsp_query-to>
      <Hsp_hit-from>427</Hsp_hit-from>
      <Hsp_hit-to>925</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>213</Hsp_identity>
      <Hsp_positive>303</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>530</Hsp_align-len>
      <Hsp_qseq>PFLIIAPLSTIANWEREFRTWT-DLNAIVYHGSLASRHIIQQYEMHHRDE-QGRAIPCAYKFDAIITTFEMILTDCPELRDIGWRCVIIDEAHRLKNRNCKLLEGLKQLNLEHKVLLTGTPLQNTVEELFSLLNFLEPARFPSEPAFLEEYGDLKTEEQASAVQKLQAILKPMMLRRLKEDVEKNLAPKEETIVEVELTNIQKKYYRAILERNFSFLAKGASGGQANLPNLMNTMMELRKCCNHPYLINGAEEKILEDFRESHGVDAMDFHLQAMIQAAGKLVLIDKLLPKLKAGGHKVLVFSQMWXXXXXXXXXXXXXXXDGCGDICRGXXXXXXXXXXXXERIDGRVRGNLRQAAIDRFCKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRENATNGVQQMSKKEIEDLLRKGAYGAIMDEEDESSKFCEEDIDQILQRRTHTITIETEGK----GSTFAKNTLVID</Hsp_qseq>
      <Hsp_hseq>PHIIVVPLSTMPAWLDTFEKWAPDLNCICYMGNQKSRDTIREYEFYTNPRAKGKK---TMKFNVLLTTYEYILKDRAELGSIKWQFMAVDEAHRLKNAESSLYESLNSFKVANRMLITGTPLQNNIKELAALVNFLMPGRFTIDQEIDFENQD---EEQEEYIHDLHRRIQPFILRRLKKDVEKSLPSKTERILRVELSDVQTEYYKNILTKNYSALTAGAKGGHFSLLNIMN---ELKKASNHPYLFDNAEERVLQKFGD--GKMTRENVLRGLIMSSGKMVLLDQLLTRLKKDGHRVLIFSQM------------VRMLDILGDYL-------SIKGINFQRLDGTVPSAQRRISIDHFNSPDSNDFVFLLSTRAGGLGINLMTADTVVIFDSDWNPQADLQAMARAHRIGQKNHVMVYRLVSKDTVEEEVLERARKKMILEYAIISLGVTDGNKYTKKNEPNAGELSAILKFGA-GNMFTATDNQKKLEDLNLDDVLNHAEDHVTTPDLGESHLGGEEFLKQFEVTD</Hsp_hseq>
      <Hsp_midline>P +I+ PLST+  W   F  W  DLN I Y G+  SR  I++YE +     +G+      KF+ ++TT+E IL D  EL  I W+ + +DEAHRLKN    L E L    + +++L+TGTPLQN ++EL +L+NFL P RF  +     E  D   EEQ   +  L   ++P +LRRLK+DVEK+L  K E I+ VEL+++Q +YY+ IL +N+S L  GA GG  +L N+MN   EL+K  NHPYL + AEE++L+ F +  G    +  L+ +I ++GK+VL+D+LL +LK  GH+VL+FSQM                D  GD               ++R+DG V    R+ +ID F  PDS+ FVFLL TRAGGLGINL  ADT +IFDSDWNPQ DLQA AR HRIGQ   V VYRL+++++ E E+ ++A  K+ L+ A++       N      + +  E+  +L+ GA G +    D   K  + ++D +L      +T    G+    G  F K   V D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YOR304W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:884514:887876:1 gene:YOR304W transcript:YOR304W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ISW2 description:ATP-dependent DNA translocase involved in chromatin remodeling; ATPase component that, with Itc1p, forms a complex required for repression of a-specific genes, INO1, and early meiotic genes during mitotic growth; the Isw2 complex exhibits basal levels of chromatin binding throughout the genome as well as target-specific chromatin interactions; targeted by Ume6p- and Sua7p-dependent DNA looping to many loci genome-wide [Source:SGD;Acc:S000005831]</Hit_def>
  <Hit_accession>YOR304W</Hit_accession>
  <Hit_len>1120</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>353.599</Hsp_bit-score>
      <Hsp_score>906</Hsp_score>
      <Hsp_evalue>1.07152e-101</Hsp_evalue>
      <Hsp_query-from>16</Hsp_query-from>
      <Hsp_query-to>1524</Hsp_query-to>
      <Hsp_hit-from>232</Hsp_hit-from>
      <Hsp_hit-to>688</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>206</Hsp_identity>
      <Hsp_positive>295</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>505</Hsp_align-len>
      <Hsp_qseq>IRRPFLIIAPLSTIANWEREFRTWT-DLNAIVYHGSLASRHIIQQYEMHHRDEQGRAIPCAYKFDAIITTFEMILTDCPELRDIGWRCVIIDEAHRLKNRNCKLLEGLKQLNLEHKVLLTGTPLQNTVEELFSLLNFLEPARFPSEPAFLEEYGDLKTEE-QASAVQKLQAILKPMMLRRLKEDVEKNLAPKEETIVEVELTNIQKKYYRAILERNFSFLAKGASGGQANLPNLMNTMMELRKCCNHPYLINGAEEKILEDFRESHGVDAMDFHLQAMIQAAGKLVLIDKLLPKLKAGGHKVLVFSQMWXXXXXXXXXXXXXXXDGCGDICRGXXXXXXXXXXXXERIDGRVRGNLRQAAIDRFCKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRENATNGVQQMSKKEIEDLLRKGAYGAIMDEEDESSKFCEEDIDQILQR</Hsp_qseq>
      <Hsp_hseq>IEGPFLIIVPKSTLDNWRREFLKWTPNVNVLVLHGDKDTRADI-----------VRNIILEARFDVLITSYEMVIREKNALKRLAWQYIVIDEAHRIKNEQSALSQIIRLFYSKNRLLITGTPLQNNLHELWALLNFLLPDIFGDSELFDEWFEQNNSEQDQEIVIQQLHSVLNPFLLRRVKADVEKSLLPKIETNVYVGMTDMQIQWYKSLLEKDIDAV-NGAVGKREGKTRLLNIVMQLRKCCNHPYLFEGA---------EPGPPYTTDEHL---IFNSGKMIILDKLLKRLKEKGSRVLIFSQM------------SRLLDILEDYCYFRDFEYC-------RIDGSTSHEERIEAIDEYNKPNSEKFVFLLTTRAGGLGINLVTADTVILFDSDWNPQADLQAMDRAHRIGQKKQVHVYRFVTENAIEEKVIERAAQKLRLDQLVIQQGTGKKTASLG---NSKDDLLDMIQFGAKN--MFEKKASKVTVDADIDDILKK</Hsp_hseq>
      <Hsp_midline>I  PFLII P ST+ NW REF  WT ++N +V HG   +R  I            R I    +FD +IT++EM++ +   L+ + W+ ++IDEAHR+KN    L + ++    ++++L+TGTPLQN + EL++LLNFL P  F     F E +    +E+ Q   +Q+L ++L P +LRR+K DVEK+L PK ET V V +T++Q ++Y+++LE++   +  GA G +     L+N +M+LRKCCNHPYL  GA         E       D HL   I  +GK++++DKLL +LK  G +VL+FSQM                D   D C               RIDG      R  AID + KP+S++FVFLL TRAGGLGINL  ADT I+FDSDWNPQ DLQA  R HRIGQ K V VYR +T N+ E ++ ++A+ KL LD+ V+Q  +G++ A+ G    SK ++ D+++ GA    M E+  S    + DID IL++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YBR245C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:708150:711539:-1 gene:YBR245C transcript:YBR245C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ISW1 description:ATPase subunit of imitation-switch (ISWI) class chromatin remodelers; with Ioc3p forms Isw1a complex involved in repression of transcription initiation; with Ioc2p and Ioc4p forms Isw1b complex involved in regulation of transcription elongation; Isw1b recruited to ORFs by H3K36 methylation and acts with Chd1p to prevent trans-histone exchange over coding regions; Isw1p import into nucleus depends on C-terminal bipartite nuclear targeting signal KRIR X19 KKAK [Source:SGD;Acc:S000000449]</Hit_def>
  <Hit_accession>YBR245C</Hit_accession>
  <Hit_len>1129</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>316.62</Hsp_bit-score>
      <Hsp_score>810</Hsp_score>
      <Hsp_evalue>2.1963e-89</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>1449</Hsp_query-to>
      <Hsp_hit-from>247</Hsp_hit-from>
      <Hsp_hit-to>679</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>198</Hsp_identity>
      <Hsp_positive>278</Hsp_positive>
      <Hsp_gaps>56</Hsp_gaps>
      <Hsp_align-len>482</Hsp_align-len>
      <Hsp_qseq>PFLIIAPLSTIANWEREFRTWT-DLNAIVYHGSLASR-HIIQQYEMHHRDEQGRAIPCAYKFDAIITTFEMILTDCPELRDIGWRCVIIDEAHRLKNRNCKLLEGLKQLNLEHKVLLTGTPLQNTVEELFSLLNFLEPARFPSEPAFLEEYGDLKTEE-QASAVQKLQAILKPMMLRRLKEDVEKNLAPKEETIVEVELTNIQKKYYRAILERNFSFLAKGASGGQANLPNLMNTMMELRKCCNHPYLINGAEEKILEDFRESHGVDAMDFHLQAMIQAAGKLVLIDKLLPKLKAGGHKVLVFSQMWXXXXXXXXXXXXXXXDGCGDICRGXXXXXXXXXXXXERIDGRVRGNLRQAAIDRFCKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQ----SMSGRENATNGVQQMSKKEIEDLLRKGA</Hsp_qseq>
      <Hsp_hseq>PFLVIAPKSTLNNWLREINRWTPDVNAFILQGDKEERAELIQK----------KLLGC--DFDVVIASYEIIIREKSPLKKINWEYIIIDEAHRIKNEESMLSQVLREFTSRNRLLITGTPLQNNLHELWALLNFLLPDIFSDAQDFDDWFSSESTEEDQDKIVKQLHTVLQPFLLRRIKSDVETSLLPKKELNLYVGMSSMQKKWYKKILEKDLD-AVNGSNGSKESKTRLLNIMMQLRKCCNHPYLFDGA---------EPGPPYTTDEHL---VYNAAKLQVLDKLLKKLKEEGSRVLIFSQM------------SRLLDILEDYCYFRNYEYC-------RIDGSTAHEDRIQAIDDYNAPDSKKFVFLLTTRAGGLGINLTSADVVVLYDSDWNPQADLQAMDRAHRIGQKKQVKVFRLVTDNSVEEKILERATQKLRLDQLVIQQNRTSLKKKENKAD-----SKDALLSMIQHGA</Hsp_hseq>
      <Hsp_midline>PFL+IAP ST+ NW RE   WT D+NA +  G    R  +IQ+          + + C   FD +I ++E+I+ +   L+ I W  +IIDEAHR+KN    L + L++    +++L+TGTPLQN + EL++LLNFL P  F     F + +    TEE Q   V++L  +L+P +LRR+K DVE +L PK+E  + V ++++QKK+Y+ ILE++      G++G + +   L+N MM+LRKCCNHPYL +GA         E       D HL   +  A KL ++DKLL KLK  G +VL+FSQM                D   D C               RIDG      R  AID +  PDS +FVFLL TRAGGLGINLT+AD  +++DSDWNPQ DLQA  R HRIGQ K VKV+RL+T NS E ++ ++A+ KL LD+ V+Q    S+  +EN  +     SK  +  +++ GA</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YIL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:117992:122071:1 gene:YIL126W transcript:YIL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STH1 description:ATPase component of the RSC chromatin remodeling complex; required for expression of early meiotic genes; promotes base excision repair in chromatin; essential helicase-related protein homologous to Snf2p [Source:SGD;Acc:S000001388]</Hit_def>
  <Hit_accession>YIL126W</Hit_accession>
  <Hit_len>1359</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>290.041</Hsp_bit-score>
      <Hsp_score>741</Hsp_score>
      <Hsp_evalue>7.28506e-80</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>1368</Hsp_query-to>
      <Hsp_hit-from>521</Hsp_hit-from>
      <Hsp_hit-to>942</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>176</Hsp_identity>
      <Hsp_positive>252</Hsp_positive>
      <Hsp_gaps>56</Hsp_gaps>
      <Hsp_align-len>463</Hsp_align-len>
      <Hsp_qseq>PFLIIAPLSTIANWEREFRTWT-DLNAIVYHGSLASRHIIQQYEMHHRDEQGRAIPCAYKFDAIITTFEMILTDCPELRDIGWRCVIIDEAHRLKNRNCKLLEGLKQL-NLEHKVLLTGTPLQNTVEELFSLLNFLEPARFPSEPAFLE----EYGDLKTEEQASA--------VQKLQAILKPMMLRRLKEDVEKNLAPKEETIVEVELTNIQKKYYRAILERNFSFLAKGASGG-QANLPNLMNTMMELRKCCNHPYLINGAEEKILEDFRESHGVDAMDFHLQAMIQAAGKLVLIDKLLPKLKAGGHKVLVFSQMWXXXXXXXXXXXXXXXDGCGDICRGXXXXXXXXXXXXERIDGRVRGNLRQAAIDRFCKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQS</Hsp_qseq>
      <Hsp_hseq>PFLVIVPLSTITNWTLEFEKWAPSLNTIIYKGTPNQRHSLQ-----HQIRVG-------NFDVLLTTYEYIIKDKSLLSKHDWAHMIIDEGHRMKNAQSKLSFTISHYYRTRNRLILTGTPLQNNLPELWALLNFVLPKIFNSAKTFEDWFNTPFANTGTQEKLELTEEETLLIIRRLHKVLRPFLLRRLKKEVEKDLPDKVEKVIKCKLSGLQQQLYQQMLKHNALFVGAGTEGATKGGIKGLNNKIMQLRKICNHPFVFDEVEGVV----NPSRGNSDLLFRV------AGKFELLDRVLPKFKASGHRVLMFFQM------------TQVMDIMEDFLRMKDLKYM-------RLDGSTKTEERTEMLNAFNAPDSDYFCFLLSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTDSVEEVILERAMQKLDIDGKVIQA</Hsp_hseq>
      <Hsp_midline>PFL+I PLSTI NW  EF  W   LN I+Y G+   RH +Q     H+   G        FD ++TT+E I+ D   L    W  +IIDE HR+KN   KL   +       ++++LTGTPLQN + EL++LLNF+ P  F S   F +     + +  T+E+           +++L  +L+P +LRRLK++VEK+L  K E +++ +L+ +Q++ Y+ +L+ N  F+  G  G  +  +  L N +M+LRK CNHP++ +  E  +      S G   + F +      AGK  L+D++LPK KA GH+VL+F QM                D   D  R              R+DG  +   R   ++ F  PDSD F FLL TRAGGLG+NL  ADT IIFD+DWNP  DLQAQ R HRIGQ   V++ RLIT +S E  + ++A  KL +D  V+Q+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YOR290C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:855147:860258:-1 gene:YOR290C transcript:YOR290C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF2 description:Catalytic subunit of the SWI/SNF chromatin remodeling complex; involved in transcriptional regulation; contains DNA-stimulated ATPase activity; functions interdependently in transcriptional activation with Snf5p and Snf6p [Source:SGD;Acc:S000005816]</Hit_def>
  <Hit_accession>YOR290C</Hit_accession>
  <Hit_len>1703</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>290.812</Hsp_bit-score>
      <Hsp_score>743</Hsp_score>
      <Hsp_evalue>1.53591e-79</Hsp_evalue>
      <Hsp_query-from>13</Hsp_query-from>
      <Hsp_query-to>1551</Hsp_query-to>
      <Hsp_hit-from>814</Hsp_hit-from>
      <Hsp_hit-to>1298</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>188</Hsp_identity>
      <Hsp_positive>278</Hsp_positive>
      <Hsp_gaps>78</Hsp_gaps>
      <Hsp_align-len>538</Hsp_align-len>
      <Hsp_qseq>GIRRPFLIIAPLSTIANWEREFRTWT-DLNAIVYHGSLASRHIIQQYEMHHRDEQGRAIPCAYKFDAIITTFEMILTDCPELRDIGWRCVIIDEAHRLKNRNCKLLEGLK-QLNLEHKVLLTGTPLQNTVEELFSLLNFLEPARFPSEPAFLEEYG------------DLKTEEQASAVQKLQAILKPMMLRRLKEDVEKNLAPKEETIVEVELTNIQKKYYRAILERNFSFLAKGASGGQANLPNLMNTMMELRKCCNHPYLINGAEEKILEDFRESHGVDAMDFHLQAMIQAAGKLVLIDKLLPKLKAGGHKVLVFSQMWXXXXXXXXXXXXXXXDGCGDICRGXXXXXXXXXXXXERIDGRVRGNLRQAAIDRFCKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRENATNGVQQMSKKEIEDLLRKGAYGAIMDEEDESSK-----------FCEEDIDQILQRRTHTITIET</Hsp_qseq>
      <Hsp_hseq>NIRGPYLVIVPLSTLSNWSSEFAKWAPTLRTISFKGSPNERKAKQ------------AKIRAGEFDVVLTTFEYIIKERALLSKVKWVHMIIDEGHRMKNAQSKLSLTLNTHYHADYRLILTGTPLQNNLPELWALLNFVLPKIFNSVKSFDEWFNTPFANTGGQDKIELSEEETLLVIRRLHKVLRPFLLRRLKKDVEKELPDKVEKVVKCKMSALQQIMYQQMLKYRRLFIGDQNNKKMVGLRGFNNQIMQLKKICNHPFVFEEVEDQI-NPTRETND---------DIWRVAGKFELLDRILPKLKATGHRVLIFFQM------------TQIMDIMEDFLRYINIKYL-------RLDGHTKSDERSELLRLFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTNSVEEVILERAYKKLDIDGKVIQAGKFDNKSTS-------EEQEALLR-----SLLDAEEERRKKRESGVEEEEELKDSEINEILARNDEEMAVLT</Hsp_hseq>
      <Hsp_midline> IR P+L+I PLST++NW  EF  W   L  I + GS   R   Q            A   A +FD ++TTFE I+ +   L  + W  +IIDE HR+KN   KL   L    + +++++LTGTPLQN + EL++LLNF+ P  F S  +F E +             +L  EE    +++L  +L+P +LRRLK+DVEK L  K E +V+ +++ +Q+  Y+ +L+    F+    +     L    N +M+L+K CNHP++    E++I    RE++           + + AGK  L+D++LPKLKA GH+VL+F QM                D   D  R              R+DG  + + R   +  F  PDS+   F+L TRAGGLG+NL  ADT IIFD+DWNP  DLQAQ R HRIGQ   V++ RLIT NS E  + ++A  KL +D  V+Q+      +T+       +E E LLR     +++D E+E  K             + +I++IL R    + + T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YFR038W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:229380:231941:1 gene:YFR038W transcript:YFR038W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IRC5 description:Putative ATPase containing the DEAD/H helicase-related sequence motif; null mutant displays increased levels of spontaneous Rad52p foci; SWAT-GFP and mCherry fusion proteins localize to the nucleus [Source:SGD;Acc:S000001934]</Hit_def>
  <Hit_accession>YFR038W</Hit_accession>
  <Hit_len>853</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>245.743</Hsp_bit-score>
      <Hsp_score>626</Hsp_score>
      <Hsp_evalue>9.21345e-68</Hsp_evalue>
      <Hsp_query-from>19</Hsp_query-from>
      <Hsp_query-to>1365</Hsp_query-to>
      <Hsp_hit-from>270</Hsp_hit-from>
      <Hsp_hit-to>753</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>171</Hsp_identity>
      <Hsp_positive>248</Hsp_positive>
      <Hsp_gaps>113</Hsp_gaps>
      <Hsp_align-len>523</Hsp_align-len>
      <Hsp_qseq>RRPFLIIAPLSTIANWEREFRTWT-DLNAIVYHGSLASRHIIQQYEMHHRDEQGRAIPCAYKFDAIITTFEMILTDCPELRDIGWRCVIIDEAHRLKNRNCKLLEGLKQLNLEHKVLLTGTPLQNTVEELFSLLNFLEPARFPSEPAF----------------LEEYGDLKTEE-QASAVQKLQAILKPMMLRRLKEDVEKN-LAPKEETIVEVELTNIQKKYYRAILE------------RNF-----------------SFLAKGASGGQAN------LPNLM--------------------NTMMELRKCCNHPYLINGAEEKILEDFRESHGVDAMDFHLQAMIQAAGKLVLIDKLLPKLKAGGHKVLVFSQMWXXXXXXXXXXXXXXXDGCGDICRGXXXXXXXXXXXXERIDGRVRGNLRQAAIDRFCKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQ</Hsp_qseq>
      <Hsp_hseq>KGPFLVTAPLSTLDNWMNEFAKFAPDLPVLKYYGTNGYKERSAKLKNFFKQHGGTGI--------VITSYEIILRDTDLIMSQNWKFLIVDEGHRLKNINCRLIKELKKINTSNRLLLTGTPLQNNLAELWSLLNFIMPDIFADFEIFNKWFDFDSLNLGSGSNSEALNKLINDELQKNLISNLHTILKPFLLRRLKKVVLANILPPKREYIINCPMTSAQEKFYKAGLNGKLKKTMFKELIKDFFTLNDEYIGHVSNRSIRDFINYKLSGNETSNTDNKINPTLLQMDKLYKKNLQMEISNKKLQNMMMQLRQIIDSTFLFY---------FPYLH---PEDLTLETLLKTSGKLQILQKLIPPLISEGHKVLIYSQF------------VNMLDLIEDWC-------DLNSFATFRIDGSVNNETRKDQLEKFNSSKDKHNIFLLSTRAAGLGINLVGADTVVLFDSDWNPQVDLQAMDRCHRIGQESPVIVYRLCCDNTIEHVILTRAANKRNLERMVIQ</Hsp_hseq>
      <Hsp_midline>+ PFL+ APLST+ NW  EF  +  DL  + Y+G+   +    + +   +   G  I        +IT++E+IL D   +    W+ +I+DE HRLKN NC+L++ LK++N  +++LLTGTPLQN + EL+SLLNF+ P  F     F                 E    L  +E Q + +  L  ILKP +LRRLK+ V  N L PK E I+   +T+ Q+K+Y+A L             ++F                  F+    SG + +       P L+                    N MM+LR+  +  +L           F   H     D  L+ +++ +GKL ++ KL+P L + GHKVL++SQ                 D   D C           +   RIDG V    R+  +++F        +FLL TRA GLGINL  ADT ++FDSDWNPQ DLQA  RCHRIGQ   V VYRL   N+ E  +  +A+ K  L++ V+Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YPL082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:398480:404083:-1 gene:YPL082C transcript:YPL082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MOT1 description:Essential protein involved in regulation of transcription; removes Spt15p (TBP) from DNA via its C-terminal ATPase activity; may have a role in ensuring that soluble TBP is available to bind TATA-less promoters; forms a complex with TBP that binds TATA DNA with high affinity but with altered specificity; the Mot1p-Spt15p-DNA ternary complex contains unbent DNA; coregulates transcription with Spt16p through assembly of preinitiation complex and organization of nucleosomes [Source:SGD;Acc:S000006003]</Hit_def>
  <Hit_accession>YPL082C</Hit_accession>
  <Hit_len>1867</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>199.519</Hsp_bit-score>
      <Hsp_score>506</Hsp_score>
      <Hsp_evalue>1.68875e-51</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>1437</Hsp_query-to>
      <Hsp_hit-from>1334</Hsp_hit-from>
      <Hsp_hit-to>1800</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>149</Hsp_identity>
      <Hsp_positive>228</Hsp_positive>
      <Hsp_gaps>78</Hsp_gaps>
      <Hsp_align-len>508</Hsp_align-len>
      <Hsp_qseq>PFLIIAPLSTIANWEREFRTWTD-LNAIVYHGSLASRHIIQQYEMHHRDEQGRAIPCAYKFDAIITTFEMILTDCPELRDIGWRCVIIDEAHRLKNRNCKLLEGLKQLNLEHKVLLTGTPLQNTVEELFSLLNFLEPARFPSEPAFLEEYG---------DLKTEEQASAVQKLQAILK---PMMLRRLKEDVEKNLAPKEETIVEVELTNIQKKYYRAILERNFSFLAKG------ASGGQANLPNLMNTMMELRKCCNHPYLI---NGAEEKILEDFRESHGVDAMDFHLQAMIQAAGKLVL--------IDKLLPKLK-------AGGHKVLVFSQMWXXXXXXXXXXXXXXXDGCGDICRGXXXXXXXXXXXXERIDGRVRGNLRQAAIDRFCKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRENATNGVQQMSKKEIEDLL</Hsp_qseq>
      <Hsp_hseq>PSLIICPPSLTGHWENEFDQYAPFLKVVVYAGGPTVRLTLR--------------PQLSDADIIVTSYDVARNDLAVLNKTEYNYCVLDEGHIIKNSQSKLAKAVKEITANHRLILTGTPIQNNVLELWSLFDFLMPGFLGTEKMFQERFAKPIAASRNSKTSSKEQEAGVLALEALHKQVLPFMLRRLKEDVLSDLPPKIIQDYYCELGDLQKQLYMDFTKKQKNVVEKDIENSEIADGKQ----HIFQALQYMRKLCNHPALVLSPNHPQLAQVQDYLKQTGLDLHDIINAPKLSALRTLLFECGIGEEDIDKKASQDQNFPIQNVISQHRALIFCQL----------------KDMLDMVENDLFKKYMPSVTYMRLDGSIDPRDRQKVVRKFNE-DPSIDCLLLTTKVGGLGLNLTGADTVIFVEHDWNPMNDLQAMDRAHRIGQKKVVNVYRIITKGTLEEKIMGLQKFKMNIASTVVNQQN------SGLASMDTHQLLDLF</Hsp_hseq>
      <Hsp_midline>P LII P S   +WE EF  +   L  +VY G    R  ++              P     D I+T++++   D   L    +   ++DE H +KN   KL + +K++   H+++LTGTP+QN V EL+SL +FL P    +E  F E +             ++EQ + V  L+A+ K   P MLRRLKEDV  +L PK       EL ++QK+ Y    ++  + + K       A G Q    ++   +  +RK CNHP L+   N  +   ++D+ +  G+D  D      + A   L+         IDK   + +          H+ L+F Q+                    D+              Y R+DG +    RQ  + +F + D      LL T+ GGLG+NLT ADT I  + DWNP NDLQA  R HRIGQ K V VYR+IT+ + E ++      K+ +   V+   +      +G+  M   ++ DL </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YJR035W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:497355:500612:1 gene:YJR035W transcript:YJR035W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD26 description:Protein involved in transcription-coupled nucleotide excision repair; repairs UV-induced DNA lesions; recruitment to DNA lesions is dependent on an elongating RNA polymerase II; homolog of human CSB protein [Source:SGD;Acc:S000003796]</Hit_def>
  <Hit_accession>YJR035W</Hit_accession>
  <Hit_len>1085</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>184.111</Hsp_bit-score>
      <Hsp_score>466</Hsp_score>
      <Hsp_evalue>3.37456e-47</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>1362</Hsp_query-to>
      <Hsp_hit-from>348</Hsp_hit-from>
      <Hsp_hit-to>803</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>132</Hsp_identity>
      <Hsp_positive>227</Hsp_positive>
      <Hsp_gaps>82</Hsp_gaps>
      <Hsp_align-len>492</Hsp_align-len>
      <Hsp_qseq>PFLIIAPLSTIANWEREFRTW-TDLNAIVYHGSLASRHIIQQYEMHHRDEQG----------------------RAIPCAYKFDAII-----------TTFEMILTDCPELRDIGWRCVIIDEAHRLKNRNCKLLEGLKQLNLEHKVLLTGTPLQNTVEELFSLLNFLEPARFPSEPAFLEEY------------GDLKTEEQASAVQKLQAILKPMMLRRLKEDVEKNLAPKEETIVEVELTNIQKKYYRAILERNFSFLAKGASGGQANLPNLMNTMMELRKCCNHPYLINGAEEKILEDFRESHGVDAMDFHLQAMIQAAGKLVLIDKLLPKLKAGGHKVLVFSQMWXXXXXXXXXXXXXXXDGCGDICRGXXXXXXXXXXXXERIDGRVRGNLRQAAIDRFCKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVL</Hsp_qseq>
      <Hsp_hseq>PVLIVCPATVMKQWCNEFQHWWPPLRTVILHSMGSGMASDQKFKMDENDLENLIMNSKPSDFSYEDWKNSTRTKKALESSYHLDKLIDKVVTDGHILITTYVGLRIHSDKLLKVKWQYAVLDEGHKIRNPDSEISLTCKKLKTHNRIILSGTPIQNNLTELWSLFDFIFPGKLGTLPVFQQQFVIPINIGGYANATNIQVQTGYKCAVALRDLISPYLLRRVKADVAKDLPQKKEMVLFCKLTKYQRSKYLEFLHS--SDLNQIQNGKR----NVLFGIDILRKICNHPDLLDRDTKR--------HNPDYGD------PKRSGKMQVVKQLLLLWHKQGYKALLFTQSRQMLDILEEFISTKDPD--------------LSHLNYLRMDGTTNIKGRQSLVDRFNNESFD--VFLLTTRVGGLGVNLTGANRIIIFDPDWNPSTDMQARERAWRIGQKREVSIYRLMVGGSIEEKIYHRQIFKQFLTNRIL</Hsp_hseq>
      <Hsp_midline>P LI+ P + +  W  EF+ W   L  ++ H   +     Q+++M   D +                       +A+  +Y  D +I           TT+  +     +L  + W+  ++DE H+++N + ++    K+L   ++++L+GTP+QN + EL+SL +F+ P +  + P F +++             +++ +        L+ ++ P +LRR+K DV K+L  K+E ++  +LT  Q+  Y   L    S L +  +G +    N++  +  LRK CNHP L++   ++        H  D  D       + +GK+ ++ +LL      G+K L+F+Q  + +            D                   Y R+DG      RQ+ +DRF     D  VFLL TR GGLG+NLT A+  IIFD DWNP  D+QA+ R  RIGQ + V +YRL+   S E +++ +   K  L   +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YAL019W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:114919:118314:1 gene:YAL019W transcript:YAL019W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUN30 description:Snf2p family member with ATP-dependent chromatin remodeling activity; has a role in silencing at the mating type locus, telomeres and centromeres; enriched at centromeres and is required for correct chromatin structure around centromeres, as well as at the boundary element of the silent HMR; recruited to DNA double-strand breaks (DSBs) where it promotes 5&apos; strand resection of DSBs; potential Cdc28p substrate [Source:SGD;Acc:S000000017]</Hit_def>
  <Hit_accession>YAL019W</Hit_accession>
  <Hit_len>1131</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>179.874</Hsp_bit-score>
      <Hsp_score>455</Hsp_score>
      <Hsp_evalue>8.27119e-46</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>1437</Hsp_query-to>
      <Hsp_hit-from>622</Hsp_hit-from>
      <Hsp_hit-to>1119</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>158</Hsp_identity>
      <Hsp_positive>236</Hsp_positive>
      <Hsp_gaps>97</Hsp_gaps>
      <Hsp_align-len>533</Hsp_align-len>
      <Hsp_qseq>PFLIIAPLSTIANWEREFRTWTD-LNAIVYHGSLASRHIIQQYEMHHRDEQGRAIPCAYKFDAIITTFEMIL---TDCPELRDIGWRCVIIDEAHRLKNRNCKLLEGLKQLNLEHKVLLTGTPLQNTVEELFSLLNFLEPARFPSEP----AFLEEYGDLKTEEQ-------ASAVQKLQAILKPMMLRRLKEDVEKNLAPKEETIVEVELTNIQKKYY----RAILE-----RNFSFLAKGASGGQANLPNLMNTMMELRKCCNHPYLI------------------------NGAEEKILEDFR-----ESH--------GVDAMDFHLQAMIQAAGKLVLIDKLLPKLKAGGH-KVLVFSQMWXXXXXXXXXXXXXXXDGCGDICRGXXXXXXXXXXXXERIDGRVRGNLRQAAIDRFCKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRENATNGVQQMSKKEIEDLL</Hsp_qseq>
      <Hsp_hseq>PHLVVVPSSTLENWLREFQKFAPALKIEPYYGSLQEREEL-------RDILER---NAGKYDVIVTTYNLAAGNKYDVSFLKNRNFNVVVYDEGHMLKNSTSERFAKLMKIRANFRLLLTGTPLQNNLKELMSLLEFIMPNLFISKKESFDAIFKQRAKTTDDNKNHNPLLAQEAITRAKTMMKPFILRRRKDQVLKHLPPKHTHIQYCELNAIQKKIYDKEIQIVLEHKRMIKDGELPKDAKEKSKLQSSSSKNLIMALRKASLHPLLFRNIYNDKIITKMSDAILDEPAYAENGNKEYIKEDMSYMTDFELHKLCCNFPNTLSKYQLHNDEWMQ-SGKIDALKKLLKTIIVDKQEKVLIFSLFTQVL----------------DILEMVLSTLDYKFL---RLDGSTQVNDRQLLIDKFYE-DKDIPIFILSTKAGGFGINLVCANNVIIFDQSFNPHDDRQAADRAHRVGQTKEVNITTLITKDSIEEKIHQLAKNKLALDSYISEDKKSQDVLESKVSDM----LEDII</Hsp_hseq>
      <Hsp_midline>P L++ P ST+ NW REF+ +   L    Y+GSL  R  +       RD   R    A K+D I+TT+ +      D   L++  +  V+ DE H LKN   +    L ++    ++LLTGTPLQN ++EL SLL F+ P  F S+     A  ++      + +         A+ + + ++KP +LRR K+ V K+L PK   I   EL  IQKK Y    + +LE     ++           +    +  N +M LRK   HP L                         NG +E I ED       E H         +     H    +Q +GK+  + KLL  +      KVL+FS   + +                DI                R+DG  + N RQ  ID+F + D D  +F+L T+AGG GINL  A+  IIFD  +NP +D QA  R HR+GQ+K V +  LIT++S E ++   A  KL LD  + +    ++   + V  M    +ED++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YBR073W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:383112:385988:1 gene:YBR073W transcript:YBR073W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RDH54 description:DNA-dependent ATPase; DNA recombination/repair translocase, supercoils DNA and promotes DNA strand opening; stimulates strand exchange by modifying dsDNA topology; involved in recombinational repair of DNA double-strand breaks (DSBs) during mitosis and meiosis; phosphorylated in Mec1p-, Rad53p-dependent way in response to one DSB; contributes to remodelling of nucleosomes; proposed to be involved in crossover interference; interacts with Dmc1p; stimulates Dmc1p and Rad51p [Source:SGD;Acc:S000000277]</Hit_def>
  <Hit_accession>YBR073W</Hit_accession>
  <Hit_len>958</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>171.785</Hsp_bit-score>
      <Hsp_score>434</Hsp_score>
      <Hsp_evalue>1.86998e-43</Hsp_evalue>
      <Hsp_query-from>10</Hsp_query-from>
      <Hsp_query-to>1437</Hsp_query-to>
      <Hsp_hit-from>383</Hsp_hit-from>
      <Hsp_hit-to>838</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>136</Hsp_identity>
      <Hsp_positive>229</Hsp_positive>
      <Hsp_gaps>58</Hsp_gaps>
      <Hsp_align-len>495</Hsp_align-len>
      <Hsp_qseq>VGIRRPFLIIAPLSTIANWEREFRTWTDLNAIVYHGSLASRHIIQQYEMHHRDEQGRAIPCAYKFDAIITTFEMILTDCPELRDIG--WRCVIIDEAHRLKNRNCKLLEGLKQLNLEHKVLLTGTPLQNTVEELFSLLNFLEPARFPSEPAF--------------LEEYGDLKTEEQASAVQKLQAILKPMMLRRLKEDVEKNLAPKEETIVEVELTNIQKKYYRAILERNFSFLAKGA--SGGQANLPNLMNTMMELRKCCNHPYLINGAEEKILEDFRESHGVDAMDFHLQAMIQAAGKLVLIDKLLPKLKAGG-HKVLVFSQMWXXXXXXXXXXXXXXXDGCGDICRGXXXXXXXXXXXXERIDGRVRGNLRQAAIDRFCKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRENATNGVQQMSKKEIEDLL</Hsp_qseq>
      <Hsp_hseq>TGLCKKILVVCPVTLIGNWKREFGKWLNLSRIGVL-TLSSRNSPDMDKMAVRN----FLKVQRTYQVLIIGYEKLLSVSEELEKNKHLIDMLVCDEGHRLKNGASKILNTLKSLDIRRKLLLTGTPIQNDLNEFFTIIDFINPGILGSFASFKRRFIIPITRARDTANRYNEELLEKGEERSKEMIEITKRFILRRTNAILEKYLPPKTDIIL------FCKPYSQQILA--FKDILQGARLDFGQLTFSSSLGLITLLKKVCNSPGLV-GSDPYYKSHIKDTQSQDSYSRSLN-----SGKLKVLMTLLEGIRKGTKEKVVVVSNYTQTLDIIENLMNMAGMSHC-------------------RLDGSIPAKQRDSIVTSFNR-NPAIFGFLLSAKSGGVGLNLVGASRLILFDNDWNPSVDLQAMSRIHRDGQKKPCFIYRLVTTGCIDEKILQRQLMKNSLSQKFLGDSEMRNKESSNDDLFNKEDLKDLF</Hsp_hseq>
      <Hsp_midline> G+ +  L++ P++ I NW+REF  W +L+ I    +L+SR+     +M  R+     +     +  +I  +E +L+   EL         ++ DE HRLKN   K+L  LK L++  K+LLTGTP+QN + E F++++F+ P    S  +F                 Y +   E+     +++  I K  +LRR    +EK L PK + I+        K Y + IL   F  + +GA    GQ    + +  +  L+K CN P L+ G++       +++   D+    L      +GKL ++  LL  ++ G   KV+V S   + +         AG   C                   R+DG +    R + +  F + +   F FLL  ++GG+G+NL  A   I+FD+DWNP  DLQA +R HR GQ K   +YRL+T    + ++  +  +K  L +  L     R   ++     +K++++DL </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YGL163C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:193707:196403:-1 gene:YGL163C transcript:YGL163C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD54 description:DNA-dependent ATPase that stimulates strand exchange; modifies the topology of double-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; member of the SWI/SNF family of DNA translocases; forms nuclear foci upon DNA replication stress [Source:SGD;Acc:S000003131]</Hit_def>
  <Hit_accession>YGL163C</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>163.31</Hsp_bit-score>
      <Hsp_score>412</Hsp_score>
      <Hsp_evalue>6.4015e-41</Hsp_evalue>
      <Hsp_query-from>31</Hsp_query-from>
      <Hsp_query-to>1368</Hsp_query-to>
      <Hsp_hit-from>367</Hsp_hit-from>
      <Hsp_hit-to>807</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>129</Hsp_identity>
      <Hsp_positive>209</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>468</Hsp_align-len>
      <Hsp_qseq>LIIAPLSTIANWEREFRTWTDLNAIV------YHGSLASRHIIQQYEMHH-RDEQGRAIPCAYKFDAIITTFEMILTDCPELRDIGWRCVIIDEAHRLKNRNCKLLEGLKQLNLEHKVLLTGTPLQNTVEELFSLLNFLEPARFPSEPAFLEEY------------GDLKTEEQASAVQKLQAILKPMMLRRLKEDVEKNLAPKEETIVEVELTNIQKKYYRAILE-RNFSFLAKGASGGQANLPNLMNTMMELRKCCNHPYLINGAEEKILEDFRESHGVDAMDFHLQAMIQA--AGKLVLIDKLLPKLKAGGHKVLVFSQMWXXXXXXXXXXXXXXXDGCGDICRGXXXXXXXXXXXXERIDGRVRGNLRQAAIDRFCKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQS</Hsp_qseq>
      <Hsp_hseq>IIVCPSSLVNNWANELIKWLGPNTLTPLAVDGKKSSMGGGNTTVSQAIHAWAQAQGRNIVKP----VLIISYETLRRNVDQLKNCNVGLMLADEGHRLKNGDSLTFTALDSISCPRRVILSGTPIQNDLSEYFALLSFSNPGLLGSRAEFRKNFENPILRGRDADATDKEITKGEAQLQKLSTIVSKFIIRRTNDILAKYLPCKYEHVIFVNLKPLQNELYNKLIKSREVKKVVKGVGGSQP-----LRAIGILKKLCNHPNLLNFEDEFDDEDDLELPDDYNMPGSKARDVQTKYSAKFSILERFLHKIKTESDDKIVLISNY-----------TQTLDLIEKMCRYKHYSAV-------RLDGTMSINKRQKLVDRFNDPEGQEFIFLLSSKAGGCGINLIGANRLILMDPDWNPAADQQALARVWRDGQKKDCFIYRFISTGTIEEKIFQRQSMKMSLSSCVVDA</Hsp_hseq>
      <Hsp_midline>+I+ P S + NW  E   W   N +          S+   +      +H     QGR I        +I ++E +  +  +L++     ++ DE HRLKN +      L  ++   +V+L+GTP+QN + E F+LL+F  P    S   F + +             D +  +  + +QKL  I+   ++RR  + + K L  K E ++ V L  +Q + Y  +++ R    + KG  G Q      +  +  L+K CNHP L+N  +E   ED  E      M       +Q   + K  ++++ L K+K      +V    +               D    +CR     A        R+DG +  N RQ  +DRF  P+   F+FLL ++AGG GINL  A+  I+ D DWNP  D QA AR  R GQ K   +YR I+  + E ++F + S+K+ L   V+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YGL150C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:221104:225573:-1 gene:YGL150C transcript:YGL150C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:INO80 description:ATPase and nucleosome spacing factor; subunit of complex containing actin and actin-related proteins that has chromatin remodeling activity and 3&apos; to 5&apos; DNA helicase activity in vitro; promotes nucleosome shifts in the 3 prime direction; has a role in modulating stress gene transcription [Source:SGD;Acc:S000003118]</Hit_def>
  <Hit_accession>YGL150C</Hit_accession>
  <Hit_len>1489</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>139.428</Hsp_bit-score>
      <Hsp_score>350</Hsp_score>
      <Hsp_evalue>2.93124e-33</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>774</Hsp_query-to>
      <Hsp_hit-from>757</Hsp_hit-from>
      <Hsp_hit-to>1021</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>79</Hsp_identity>
      <Hsp_positive>142</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>269</Hsp_align-len>
      <Hsp_qseq>PFLIIAPLSTIANWEREFRTW-TDLNAIVYHGSLASRHIIQQYEMHHRDEQGRAIPCAYKFDAIITTFEMILTDCPELRDIGWRCVIIDEAHRLKNRNCKLLEGLKQLNLEHKVLLTGTPLQNTVEELFSLLNFLEPARFPSEPAF-------LEEYGDLKTEEQASAVQKLQAILKPMMLRRLKEDVEKNLAPKEETIVEVELTNIQKKYYRAI---LERNFSFLAKGASGGQANLP--------NLMNTMMELRKCCNHPYLINGAE</Hsp_qseq>
      <Hsp_hseq>PFLVVTPASTLHNWVNEISKFLPQFKILPYWGNANDRKVLRKFWDRKNLRYNKNAP----FHVMVTSYQMVVTDANYLQKMKWQYMILDEAQAIKSSQSSRWKNLLSFHCRNRLLLTGTPIQNSMQELWALLHFIMPSLFDSHDEFNEWFSKDIESHAEANTKLNQQQLRRLHMILKPFMLRRVKKNVQSELGDKIEIDVLCDLTQRQAKLYQVLKSQISTNYDAIENAATNDSTSNSASNSGSDQNLINAVMQFRKVCNHPDLFERAD</Hsp_hseq>
      <Hsp_midline>PFL++ P ST+ NW  E   +      + Y G+   R +++++         +  P    F  ++T+++M++TD   L+ + W+ +I+DEA  +K+      + L   +  +++LLTGTP+QN+++EL++LL+F+ P+ F S   F       +E + +  T+     +++L  ILKP MLRR+K++V+  L  K E  V  +LT  Q K Y+ +   +  N+  +   A+    +          NL+N +M+ RK CNHP L   A+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>114.775</Hsp_bit-score>
      <Hsp_score>286</Hsp_score>
      <Hsp_evalue>9.38537e-26</Hsp_evalue>
      <Hsp_query-from>775</Hsp_query-from>
      <Hsp_query-to>1386</Hsp_query-to>
      <Hsp_hit-from>1276</Hsp_hit-from>
      <Hsp_hit-to>1455</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>204</Hsp_align-len>
      <Hsp_qseq>EKILEDFRESHGVDAMDFHLQAMIQAAGKLVLIDKLLPKLKAGGHKVLVFSQMWXXXXXXXXXXXXXXXDGCGDICRGXXXXXXXXXXXXERIDGRVRGNLRQAAIDRFCKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGREN</Hsp_qseq>
      <Hsp_hseq>EPLNKNFSSNISMPSMD----RFITESAKLRKLDELLVKLKSEGHRVLIYFQMTKMMDLMEEYLTYRQYNHI-------------------RLDGSSKLEDRRDLVHDW-QTNPEIFVFLLSTRAGGLGINLTAADTVIFYDSDWNPTIDSQAMDRAHRLGQTRQVTVYRLLVRGTIEERMRDRAKQKEQVQQVVMEGKTQEKN</Hsp_hseq>
      <Hsp_midline>E + ++F  +  + +MD      I  + KL  +D+LL KLK+ GH+VL++ QM + +            +                     R+DG  +   R+  +  + + + + FVFLL TRAGGLGINLTAADT I +DSDWNP  D QA  R HR+GQ++ V VYRL+ R + E  M D+A  K  + + V++  +  +N</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YDR334W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1135932:1140476:1 gene:YDR334W transcript:YDR334W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWR1 description:Swi2/Snf2-related ATPase; structural component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; relocalizes to the cytosol in response to hypoxia; chronological aging factor that mediates lifespan extension by dietary restriction [Source:SGD;Acc:S000002742]</Hit_def>
  <Hit_accession>YDR334W</Hit_accession>
  <Hit_len>1514</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>131.339</Hsp_bit-score>
      <Hsp_score>329</Hsp_score>
      <Hsp_evalue>9.09315e-31</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>762</Hsp_query-to>
      <Hsp_hit-from>747</Hsp_hit-from>
      <Hsp_hit-to>999</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>85</Hsp_identity>
      <Hsp_positive>129</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>268</Hsp_align-len>
      <Hsp_qseq>PFLIIAPLSTIANWEREFRTWTD-LNAIVYHGSLASRHIIQQYEMHHRDEQGRAIPCAYKFDAIITTFEMILTDCPELRDIGWRCVIIDEAHRLKNRNCKLLEGLKQLNLEHKVLLTGTPLQNTVEELFSLLNFLEP---------ARFPSEPAFLEEYGDL------------KTEEQASAVQKLQAILKPMMLRRLKEDVEKNLAPKEETIVEVELTNIQKKYYRAILERNFSFLAKGASGGQANLPNLMNTMMELRKCCNHPYLI</Hsp_qseq>
      <Hsp_hseq>PHLIVVPTSVLLNWEMEFKRFAPGFKVLTYYGSPQQRK---------EKRKGWNKPDA--FHVCIVSYQLVVQDQHSFKRKRWQYMVLDEAHNIKNFRSTRWQALLNFNTQRRLLLTGTPLQNNLAELWSLLYFLMPQTVIDGKKVSGFADLDAFQQWFGRPVDKIIETGQNFGQDKETKKTVAKLHQVLRPYLLRRLKADVEKQMPAKYEHIVYCKLSKRQRFLYDDFMSR----AQTKATLASGNFMSIVNCLMQLRKVCNHPNLF</Hsp_hseq>
      <Hsp_midline>P LI+ P S + NWE EF+ +      + Y+GS   R             +G   P A  F   I ++++++ D    +   W+ +++DEAH +KN      + L   N + ++LLTGTPLQN + EL+SLL FL P         + F    AF + +G              + +E    V KL  +L+P +LRRLK DVEK +  K E IV  +L+  Q+  Y   + R        A+    N  +++N +M+LRK CNHP L </Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>113.62</Hsp_bit-score>
      <Hsp_score>283</Hsp_score>
      <Hsp_evalue>2.71722e-25</Hsp_evalue>
      <Hsp_query-from>856</Hsp_query-from>
      <Hsp_query-to>1365</Hsp_query-to>
      <Hsp_hit-from>1246</Hsp_hit-from>
      <Hsp_hit-to>1395</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>170</Hsp_align-len>
      <Hsp_qseq>GKLVLIDKLLPKLKAGGHKVLVFSQMWXXXXXXXXXXXXXXXDGCGDICRGXXXXXXXXXXXXERIDGRVRGNLRQAAIDRFCKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQ</Hsp_qseq>
      <Hsp_hseq>GKLQKLAILLQQLKDNGHRALIFTQMTK-------------------VLDVLEQFLNYHGYLYMRLDGATKIEDRQILTERF-NTDSRITVFILSSRSGGLGINLTGADTVIFYDSDWNPAMDKQCQDRCHRIGQTRDVHIYRFVSEHTIESNILKKANQKRQLDNVVIQ</Hsp_hseq>
      <Hsp_midline>GKL  +  LL +LK  GH+ L+F+QM +                   +            Y Y R+DG  +   RQ   +RF   DS   VF+L +R+GGLGINLT ADT I +DSDWNP  D Q Q RCHRIGQ++ V +YR ++ ++ E  +  KA+ K  LD  V+Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YLR032W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:204991:208500:1 gene:YLR032W transcript:YLR032W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD5 description:DNA helicase/Ubiquitin ligase; involved in error-free DNA damage tolerance (DDT), replication fork regression during postreplication repair by template switching, error-prone translesion synthesis; promotes synthesis of free and PCNA-bound polyubiquitin chains by Ubc13p-Mms2p; forms nuclear foci upon DNA replication stress; associates with native telomeres, cooperates with homologous recombination in senescent cells; human homolog HLTF can complement yeast null mutant [Source:SGD;Acc:S000004022]</Hit_def>
  <Hit_accession>YLR032W</Hit_accession>
  <Hit_len>1169</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.485</Hsp_bit-score>
      <Hsp_score>184</Hsp_score>
      <Hsp_evalue>8.29066e-14</Hsp_evalue>
      <Hsp_query-from>31</Hsp_query-from>
      <Hsp_query-to>777</Hsp_query-to>
      <Hsp_hit-from>589</Hsp_hit-from>
      <Hsp_hit-to>853</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>279</Hsp_align-len>
      <Hsp_qseq>LIIAPLSTIANWEREF---RTWTDLNAIVYHGSLASRHIIQQYEMHHRDEQGRAIPCAYKFDAIITTFEMI-----------LTD-----CPELRDIGWRCVIIDEAHRLKNRNCKLLEGLKQLNLEHKVLLTGTPLQNTVEELFSLLNFLE--PAR-FPSEPAFLEEYGDLKTEEQASAVQKLQAILKPMMLRRLKEDVEKN------LAPKEETIVEVELTNIQKKYYRAILERNFSFLAKGASGGQ--ANLPNLMNTMMELRKCCNHPYLINGAEE</Hsp_qseq>
      <Hsp_hseq>LIVVPMSLLTQWSNEFTKANNSPDMYHEVYYGGNVSSLKTLLTKTKTPPT------------VVLTTYGIVQNEWTKHSKGRMTDEDVNISSGLFSVNFYRIIIDEGHNIRNRTTVTSKAVMALQGKCKWVLTGTPIINRLDDLYSLVKFLELDPWRQINYWKTFVSTPFESKNYKQAFDV--VNAILEPVLLRRTKQMKDKDGKPLVELPPKEVVIKRLPFSKSQDLLYKFLLDKAEVSVKSGIARGDLLKKYSTILVHILRLRQVCCHPGLIGSQDE</Hsp_hseq>
      <Hsp_midline>LI+ P+S +  W  EF       D+   VY+G   S       +                   ++TT+ ++           +TD        L  + +  +IIDE H ++NR     + +  L  + K +LTGTP+ N +++L+SL+ FLE  P R       F+    + K  +QA  V  + AIL+P++LRR K+  +K+      L PKE  I  +  +  Q   Y+ +L++    +  G + G        ++  ++ LR+ C HP LI   +E</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>8.32413e-12</Hsp_evalue>
      <Hsp_query-from>1048</Hsp_query-from>
      <Hsp_query-to>1320</Hsp_query-to>
      <Hsp_hit-from>1045</Hsp_hit-from>
      <Hsp_hit-to>1136</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>92</Hsp_align-len>
      <Hsp_qseq>RIDGRVRGNLRQAAIDRFCKPDSDR-FVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMF</Hsp_qseq>
      <Hsp_hseq>KFDGRLSLKERTSVLADFAVKDYSRQKILLLSLKAGGVGLNLTCASHAYMMDPWWSPSMEDQAIDRLHRIGQTNSVKVMRFIIQDSIEEKML</Hsp_hseq>
      <Hsp_midline>+ DGR+    R + +  F   D  R  + LL  +AGG+G+NLT A    + D  W+P  + QA  R HRIGQ+ +VKV R I ++S E +M </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YOR191W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:692475:697334:1 gene:YOR191W transcript:YOR191W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ULS1 description:Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL); required for maintenance of NHEJ inhibition at telomeres; functions at telomeres to translocate and ubiquitinylate poly-sumoylated Rap1p for proteosomal degradation; plays role in antagonizing silencing during mating-type switching; only known STUbL with a translocase activity; contains RING finger domain; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005717]</Hit_def>
  <Hit_accession>YOR191W</Hit_accession>
  <Hit_len>1619</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>3.44846e-12</Hsp_evalue>
      <Hsp_query-from>31</Hsp_query-from>
      <Hsp_query-to>780</Hsp_query-to>
      <Hsp_hit-from>997</Hsp_hit-from>
      <Hsp_hit-to>1287</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>130</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>294</Hsp_align-len>
      <Hsp_qseq>LIIAPLSTIANWEREFRT-----------------------WTDL---NAIVYHGSLASRHIIQQYEMHHRDEQGR--AIPCAYKFDAIITTFEMILTDCPEL-RDIGWRCVIIDEAHRLKNRNCKLLEGLKQLNLEHKVLLTGTPLQNTVEELFSLLNFLEPARFPSEPAFLEEYG---------DLKTEEQASAVQKLQAILKPMMLRRLKEDVEK-----NLAPKEETIVEVELTNIQKKYYRAILERNFSFLAKGASGG-QANLPNLMNTMMELRKCCNHPYLINGAEEK</Hsp_qseq>
      <Hsp_hseq>LIVAPVSVLRVWKGELETKVKKRAKFTTFIFGGSGNGKVKHWRDLARYDAVLVSYQTLANEFKKHWPKKLDGEQNQLPAVPHIQALNRLKTSNEYY---SPFFCNDSTFYRILLDEGQNIKNKNTRASKACCTINGMYRWVLSGTPIQNSMDELYSLIRFLRIPPYHKEQRFKLDIGRFFQRNKQYQYDNEDRKNALRKVRVLLNAIMLRRSKADKIDGKPLLELPPKIVEVDESRLKGEELKFYTALESKNQALAKKLLNNSTRGSYSSVLTLLLRLRQACCHSELVVMGEKK</Hsp_hseq>
      <Hsp_midline>LI+AP+S +  W+ E  T                       W DL   +A++      +    + +      EQ +  A+P     + + T+ E      P    D  +  +++DE   +KN+N +  +    +N  ++ +L+GTP+QN+++EL+SL+ FL    +  E  F  + G             E++ +A++K++ +L  +MLRR K D         L PK   + E  L   + K+Y A+  +N +   K  +   + +  +++  ++ LR+ C H  L+   E+K</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>4.5703e-11</Hsp_evalue>
      <Hsp_query-from>1057</Hsp_query-from>
      <Hsp_query-to>1329</Hsp_query-to>
      <Hsp_hit-from>1494</Hsp_hit-from>
      <Hsp_hit-to>1593</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>101</Hsp_align-len>
      <Hsp_qseq>GRVRGNLRQAAIDRFCKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYE----------REMFDKA</Hsp_qseq>
      <Hsp_hseq>GSMNAQRRSDVINEFYR-DPEKRILLISMKAGNSGLTLTCANHVVIVDPFWNPYVEEQAQDRCYRISQTKKVQVHKLFIKDSVEDRISELQKRKKEMVDSA</Hsp_hseq>
      <Hsp_midline>G +    R   I+ F + D ++ + L+  +AG  G+ LT A+  +I D  WNP  + QAQ RC+RI Q+K V+V++L  ++S E          +EM D A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YBR114W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:467248:469620:1 gene:YBR114W transcript:YBR114W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD16 description:Nucleotide excision repair (NER) protein; binds damaged DNA during NER; binds DNA in an ATP-dependent manner (with Rad7p) during NER; required for NER of non-transcribed chromatin; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex [Source:SGD;Acc:S000000318]</Hit_def>
  <Hit_accession>YBR114W</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>1.08913e-10</Hsp_evalue>
      <Hsp_query-from>19</Hsp_query-from>
      <Hsp_query-to>762</Hsp_query-to>
      <Hsp_hit-from>230</Hsp_hit-from>
      <Hsp_hit-to>520</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>124</Hsp_positive>
      <Hsp_gaps>83</Hsp_gaps>
      <Hsp_align-len>311</Hsp_align-len>
      <Hsp_qseq>RRPFLIIAPLSTIANWEREFRTWT--DLNAIVYHGSLASRHIIQQYEMHHRDEQGRAIPCAYKFDAIITTFEMI----------------LTDCPE-LRDIGWRCVIIDEAHRLKNRNCKLLEGLKQLNLEHKVLLTGTPLQNTVEELFSLLNFLEPARFPSE-----------------------PAFLEEYGDLKTEEQASAVQK-------------LQAILKPMMLRRLKEDVEK----NLAPKEETIVEVELTNIQKKYYRAIL---ERNF-SFLAKGASGGQANLPNLMNTMMELRKCCNHPYLI</Hsp_qseq>
      <Hsp_hseq>KSPSLVVAPTVALMQWKNEIEQHTKGQLKIYIYHGASRTTDI--------KDLQG--------YDVVLTTYAVLESVFRKQNYGFRRKNGLFKQPSVLHNIDFYRVILDEAHNIKDRQSNTARAVNNLKTQKRWCLSGTPLQNRIGEMYSLIRFLNINPFTKYFCTKCDCASKDWKFTDRMHCDHCSHVIMQHTNFFNHFMLKNIQKFGVEGPGLESFNNIQTLLKNIMLRRTK--VERADDLGLPPRIVTVRRDFFNEEEKDLYRSLYTDSKRKYNSFVEEGVVLN--NYANIFTLITRMRQLADHPDLV</Hsp_hseq>
      <Hsp_midline>+ P L++AP   +  W+ E    T   L   +YHG+  +  I        +D QG        +D ++TT+ ++                L   P  L +I +  VI+DEAH +K+R       +  L  + +  L+GTPLQN + E++SL+ FL    F                             + ++ +         +QK             +Q +LK +MLRR K  VE+     L P+  T+        +K  YR++    +R + SF+ +G      N  N+   +  +R+  +HP L+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>2.43908e-08</Hsp_evalue>
      <Hsp_query-from>1126</Hsp_query-from>
      <Hsp_query-to>1362</Hsp_query-to>
      <Hsp_hit-from>691</Hsp_hit-from>
      <Hsp_hit-to>769</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>41</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>79</Hsp_align-len>
      <Hsp_qseq>VFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVL</Hsp_qseq>
      <Hsp_hseq>VFLVSLKAGGVALNLCEASQVFILDPWWNPSVEWQSGDRVHRIGQYRPVKITRFCIEDSIEARIIELQEKKANMIHATI</Hsp_hseq>
      <Hsp_midline>VFL+  +AGG+ +NL  A    I D  WNP  + Q+  R HRIGQ + VK+ R    +S E  + +    K  +  A +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>105</Statistics_hsp-len>
      <Statistics_eff-space>4799725787</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058728-RA transcript Note:&quot;Similar to CHD9 Chromodomain-helicase-DNA-binding protein 9 (Homo sapiens)&quot; offset:0 AED:0.83 eAED:0.83 QI:0|0|0|0.42|1|1|7|0|376</Iteration_query-def>
  <Iteration_query-len>1131</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>661651562</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058729-RA transcript Note:&quot;Protein of unknown function&quot; offset:415 AED:0.18 eAED:0.18 QI:415|0.33|0.28|0.85|0.83|0.71|7|0|648</Iteration_query-def>
  <Iteration_query-len>2362</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1568968230</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058730-RA transcript Note:&quot;Similar to UQCRFS1 Cytochrome b-c1 complex subunit Rieske, mitochondrial (Saimiri sciureus)&quot; offset:196 AED:0.03 eAED:0.03 QI:196|0.5|0.8|0.8|0.75|0.6|5|1187|243</Iteration_query-def>
  <Iteration_query-len>2115</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YEL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:107260:107907:1 gene:YEL024W transcript:YEL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIP1 description:Ubiquinol-cytochrome-c reductase; a Rieske iron-sulfur protein of the mitochondrial cytochrome bc1 complex; transfers electrons from ubiquinol to cytochrome c1 during respiration; during import, Rip1p is first imported into the mitochondrial matrix where it is processed, acquires its Fe-S cluster, and is folded, then is translocated into the inner membrane by the action of a homo-oligomer of Bcs1p, and finally is delivered by Bcs1p to Complex III for assembly [Source:SGD;Acc:S000000750]</Hit_def>
  <Hit_accession>YEL024W</Hit_accession>
  <Hit_len>215</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>189.889</Hsp_bit-score>
      <Hsp_score>481</Hsp_score>
      <Hsp_evalue>1.8033e-56</Hsp_evalue>
      <Hsp_query-from>518</Hsp_query-from>
      <Hsp_query-to>925</Hsp_query-to>
      <Hsp_hit-from>81</Hsp_hit-from>
      <Hsp_hit-to>215</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>82</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>TLSASADVMAMAKIEVKLNNIGEGQNVTLKWRGKPLFIRHRTAEEVNVEQKVNLADLRHPEHDNERAKKPEWLIVLGVCTHLGCVPIPNMGEYNGYYCPCHGSHYDNSGRIRKGPAPLNLEVPYYEFLDEDTVVVG</Hsp_qseq>
      <Hsp_hseq>SMTATADVLAMAKVEVNLAAIPLGKNVVVKWQGKPVFIRHRTPHEIQEANSVDMSALKDPQTDADRVKDPQWLIMLGICTHLGCVPIGEAGDFGGWFCPCHGSHYDISGRIRKGPAPLNLEIPAYEF-DGDKVIVG</Hsp_hseq>
      <Hsp_midline>+++A+ADV+AMAK+EV L  I  G+NV +KW+GKP+FIRHRT  E+     V+++ L+ P+ D +R K P+WLI+LG+CTHLGCVPI   G++ G++CPCHGSHYD SGRIRKGPAPLNLE+P YEF D D V+VG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1382511136</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058732-RA transcript Note:&quot;Similar to KIAA0355 Uncharacterized protein KIAA0355 (Homo sapiens)&quot; offset:0 AED:0.00 eAED:0.00 QI:0|1|1|1|0.28|0.2|15|1439|744</Iteration_query-def>
  <Iteration_query-len>3674</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2523905441</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0044051-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.69 eAED:0.76 QI:0|0|0|0.66|0|0|3|0|81</Iteration_query-def>
  <Iteration_query-len>246</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>54</Statistics_hsp-len>
      <Statistics_eff-space>71614676</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058733-RA transcript Note:&quot;Similar to Rprd1a Regulation of nuclear pre-mRNA domain-containing protein 1A (Mus musculus)&quot; offset:396 AED:0.06 eAED:0.06 QI:396|0.75|1|1|1|1|5|2576|274</Iteration_query-def>
  <Iteration_query-len>3797</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2616051588</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

