<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0052648-RA transcript Note:&quot;Similar to UNC13B Protein unc-13 homolog B (Homo sapiens)&quot; offset:0 AED:0.15 eAED:0.15 QI:0|0.51|0.43|0.93|0.68|0.8|30|0|1128</BlastOutput_query-def>
  <BlastOutput_query-len>3387</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052648-RA transcript Note:&quot;Similar to UNC13B Protein unc-13 homolog B (Homo sapiens)&quot; offset:0 AED:0.15 eAED:0.15 QI:0|0.51|0.43|0.93|0.68|0.8|30|0|1128</Iteration_query-def>
  <Iteration_query-len>3387</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2319434943</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0027284-RA transcript Note:&quot;Similar to UNC13C Protein unc-13 homolog C (Homo sapiens)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0|0.33|3|0|318</Iteration_query-def>
  <Iteration_query-len>957</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>531295343</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052649-RA transcript Note:&quot;Similar to UNC13B Protein unc-13 homolog B (Homo sapiens)&quot; offset:0 AED:0.65 eAED:0.65 QI:0|0|0|0.25|1|1|8|0|310</Iteration_query-def>
  <Iteration_query-len>933</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>89</Statistics_hsp-len>
      <Statistics_eff-space>516520074</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052652-RA transcript Note:&quot;Similar to ONECUT2 One cut domain family member 2 (Homo sapiens)&quot; offset:0 AED:0.10 eAED:0.11 QI:0|0|0|0.5|1|1|2|0|488</Iteration_query-def>
  <Iteration_query-len>1467</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>905998465</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0029998-RA transcript Note:&quot;Similar to Onecut1 Hepatocyte nuclear factor 6 (Mus musculus)&quot; offset:0 AED:0.02 eAED:0.05 QI:0|-1|0|1|-1|1|1|0|100</Iteration_query-def>
  <Iteration_query-len>303</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>71</Statistics_hsp-len>
      <Statistics_eff-space>73364010</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0029997-RA transcript Note:&quot;Protein of unknown function&quot; offset:603 AED:1.00 eAED:1.00 QI:603|0|0|0|0.13|0.25|16|568|235</Iteration_query-def>
  <Iteration_query-len>1879</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1208647510</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052655-RA transcript Note:&quot;Similar to ARPP19 cAMP-regulated phosphoprotein 19 (Gallus gallus)&quot; offset:237 AED:0.00 eAED:0.00 QI:237|1|1|1|1|1|3|5535|122</Iteration_query-def>
  <Iteration_query-len>6141</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>105</Statistics_hsp-len>
      <Statistics_eff-space>4313312114</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052656-RA transcript Note:&quot;Similar to MYO5A Unconventional myosin-Va (Homo sapiens)&quot; offset:213 AED:0.17 eAED:0.20 QI:213|0.11|0.11|0.71|1|1|35|2805|1100</Iteration_query-def>
  <Iteration_query-len>6321</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YOR326W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:925721:930445:1 gene:YOR326W transcript:YOR326W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MYO2 description:Type V myosin motor involved in actin-based transport of cargos; required for the polarized delivery of secretory vesicles, the vacuole, late Golgi elements, peroxisomes, and the mitotic spindle; MYO2 has a paralog, MYO4, that arose from the whole genome duplication [Source:SGD;Acc:S000005853]</Hit_def>
  <Hit_accession>YOR326W</Hit_accession>
  <Hit_len>1574</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>469.544</Hsp_bit-score>
      <Hsp_score>1207</Hsp_score>
      <Hsp_evalue>1.54022e-137</Hsp_evalue>
      <Hsp_query-from>10</Hsp_query-from>
      <Hsp_query-to>1572</Hsp_query-to>
      <Hsp_hit-from>65</Hsp_hit-from>
      <Hsp_hit-to>596</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>252</Hsp_identity>
      <Hsp_positive>348</Hsp_positive>
      <Hsp_gaps>77</Hsp_gaps>
      <Hsp_align-len>565</Hsp_align-len>
      <Hsp_qseq>NPDILVGENDLTALSYLHEPAVLHNLKVRFAESNHIYTYCGIVLVAINPYEQLP-IYGEDIIFAYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASE--------ANIEEKVLASNPIMERHGCLYSASPAEHLNSKS--QGNSSRFGKYIEIGFNRQYLIVGANMRTYLLEKSRVVFQA-------------------------------FVYTAQGGNAVIEDVDDGEDLERTRRAFTLLGIGASYQMGIFKIIAGILHLGNVEVQSQDREQETCFVNKEDKHLNIFCELLGLERDQMAHWLCHRKISTGAETYVKPMGRTQAQNARDALAKHVYAQLFSWIEMDGLHQAIDLGKVVSRWQAFNVDEARNDXXXXXXXXXXXXXPPNRFETFEINSFEQFCINYANEKLQQQFNLHVFKLEQEEYMREEIPWTLIDFYDNQPCIDLIEAKLGVLDLLDEECKMPKGSDQSWAQKLYEK--HLGRGKHFLKPRMSNVAFIICHFADKVEYQCDGFLEKNRDTVYEEQINILKAS</Hsp_qseq>
      <Hsp_hseq>NPPILEATEDLTSLSYLNEPAVLHAIKQRYSQLN-IYTYSGIVLIATNPFDRVDQLYTQDMIQAYAGKRRGELEPHLFAIAEEAYRLMKNDKQNQTIVVSGESGAGKTVSAKYIMRYFASVEEENSATVQHQVEMSETEQKILATNPIMEAFG-----------NAKTTRNDNSSRFGKYLEILFDKDTSIIGARIRTYLLERSRLVYQPPIERNYHIFYQLMAGLPAQTKEELHLTDASDYFYMNQGGDTKINGIDDAKEYKITVDALTLVGITKETQHQIFKILAALLHIGNIEIK---KTRNDASLSADEPNLKLACELLGIDAYNFAKWVTKKQIITRSEKIVSNLNYSQALVAKDSVAKFIYSALFDWL--------------VENINTVLCNPAVNDQISSFIGVLDIYG----FEHFEKNSFEQFCINYANEKLQQEFNQHVFKLEQEEYVKEEIEWSFIEFNDNQPCIDLIENKLGILSLLDEESRLPAGSDESWTQKLYQTLDKSPTNKVFSKPRFGQTKFIVSHYALDVAYDVEGFIEKNRDTVSDGHLEVLKAS</Hsp_hseq>
      <Hsp_midline>NP IL    DLT+LSYL+EPAVLH +K R+++ N IYTY GIVL+A NP++++  +Y +D+I AY+G+  G+++PH+FA+AEEAY+ M  D++NQ+I+VSGESGAGKTVSAKY MRYFA+V    S         +  E+K+LA+NPIME  G           N+K+    NSSRFGKY+EI F++   I+GA +RTYLLE+SR+V+Q                                + Y  QGG+  I  +DD ++ + T  A TL+GI    Q  IFKI+A +LH+GN+E++   + +    ++ ++ +L + CELLG++    A W+  ++I T +E  V  +  +QA  A+D++AK +Y+ LF W+              V        + A ND +        +      FE FE NSFEQFCINYANEKLQQ+FN HVFKLEQEEY++EEI W+ I+F DNQPCIDLIE KLG+L LLDEE ++P GSD+SW QKLY+        K F KPR     FI+ H+A  V Y  +GF+EKNRDTV +  + +LKAS</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>179.874</Hsp_bit-score>
      <Hsp_score>455</Hsp_score>
      <Hsp_evalue>1.26121e-45</Hsp_evalue>
      <Hsp_query-from>1597</Hsp_query-from>
      <Hsp_query-to>2382</Hsp_query-to>
      <Hsp_hit-from>680</Hsp_hit-from>
      <Hsp_hit-to>950</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>102</Hsp_identity>
      <Hsp_positive>158</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>271</Hsp_align-len>
      <Hsp_qseq>FDPKRAVQQLRACGVLETIRLSAAGYPSRWTYQEFFNRYRVLM---------RKKDIVSDDKKQTVQNVLEHVIKDPDKFQFGKTKIFFRAGQVAYLEKLRADKLRAACIKMQKTIRGWLQRKRYLRMRAAAITIQRHVRGHQARRLAQFMRSTRAAVIIQTXXXXXXXXXXXXKIRRTAIRMQARARGIFARQRYQQMLYRHKAVVLQKHVRGWLARRLVQRELHAVVHLQCCVRRMRARRQLKQLRIEARSVEHYKTLHKGMENKVVQL</Hsp_qseq>
      <Hsp_hseq>FDNLMVLSQLRACGVLETIRISCAGFPSRWTFEEFVLRYYILIPHEQWDLIFKKKETTEEDIISVVKMILDATVKDKSKYQIGNTKIFFKAGMLAYLEKLRSNKMHNSIVMIQKKIRAKYYRKQYLQISQAIKYLQNNIKGFIIRQRVNDEMKVNCATLLQAAYRGHSIRANVFSVLRTITNLQKKIRKELKQRQLKQEHEYNAAVTIQSKVRTFEPRSRFLRTKKDTVVVQSLIRRRAAQRKLKQLKADAKSVNHLKEVSYKLENKVIEL</Hsp_hseq>
      <Hsp_midline>FD    + QLRACGVLETIR+S AG+PSRWT++EF  RY +L+         +KK+   +D    V+ +L+  +KD  K+Q G TKIFF+AG +AYLEKLR++K+  + + +QK IR    RK+YL++  A   +Q +++G   R+          A ++Q AYR + +R     + RT   +Q + R    +++ +Q    + AV +Q  VR +  R    R     V +Q  +RR  A+R+LKQL+ +A+SV H K +   +ENKV++L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YAL029C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:87855:92270:-1 gene:YAL029C transcript:YAL029C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MYO4 description:Type V myosin motor involved in actin-based transport of cargos; required for mRNA transport, including ASH1 mRNA, and facilitating the growth and movement of ER tubules into the growing bud along with She3p; MYO4 has a paralog, MYO2, that arose from the whole genome duplication [Source:SGD;Acc:S000000027]</Hit_def>
  <Hit_accession>YAL029C</Hit_accession>
  <Hit_len>1471</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>452.595</Hsp_bit-score>
      <Hsp_score>1163</Hsp_score>
      <Hsp_evalue>1.71799e-132</Hsp_evalue>
      <Hsp_query-from>10</Hsp_query-from>
      <Hsp_query-to>1572</Hsp_query-to>
      <Hsp_hit-from>66</Hsp_hit-from>
      <Hsp_hit-to>597</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>244</Hsp_identity>
      <Hsp_positive>345</Hsp_positive>
      <Hsp_gaps>73</Hsp_gaps>
      <Hsp_align-len>563</Hsp_align-len>
      <Hsp_qseq>NPDILVGENDLTALSYLHEPAVLHNLKVRFAESNHIYTYCGIVLVAINPYEQLP-IYGEDIIFAYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVG------GSASEANIEEKVLASNPIMERHGCLYSASPAEHLNSKS--QGNSSRFGKYIEIGFNRQYLIVGANMRTYLLEKSRVVFQA-------------------------------FVYTAQGGNAVIEDVDDGEDLERTRRAFTLLGIGASYQMGIFKIIAGILHLGNVEVQSQDREQETCFVNKEDKHLNIFCELLGLERDQMAHWLCHRKISTGAETYVKPMGRTQAQNARDALAKHVYAQLFSWIEMDGLHQAIDLGKVVSRWQAFNVDEARNDXXXXXXXXXXXXXPPNRFETFEINSFEQFCINYANEKLQQQFNLHVFKLEQEEYMREEIPWTLIDFYDNQPCIDLIEAKLGVLDLLDEECKMPKGSDQSWAQKLYE--KHLGRGKHFLKPRMSNVAFIICHFADKVEYQCDGFLEKNRDTVYEEQINILKAS</Hsp_qseq>
      <Hsp_hseq>NPPILESTDDLTTLSYLNEPAVLHAIKKRYM-NGQIYTYSGIVLIAANPFDKVDHLYSREMIQNYSSKRKDELEPHLFAIAEEAYRFMVHEKANQTVVVSGESGAGKTVSAKYIMRYFASVQESNNREGEVEMSQIESQILATNPIMEAFG-----------NAKTTRNDNSSRFGKYLQILFDENTTIRGSKIRTYLLEKSRLVYQPETERNYHIFYQILEGLPEPVKQELHLSSPKDYHYTNQGGQPNIAGIDEAREYKITTDALSLVGINHETQLGIFKILAGLLHIGNIEMKMTRNDAS---LSSEEQNLQIACELLGIDPFNFAKWIVKKQIVTRSEKIVTNLNYNQALIARDSVAKFIYSTLFDWL-VDNINKTLYDPELDQQDHVFSFIGILDIYG---------------FEHFEKNSFEQFCINYANEKLQQEFNQHVFKLEQEEYVKEEIEWSFIEFSDNQPCIDLIENKLGILSLLDEESRLPSGSDESWASKLYSAFNKPPSNEVFSKPRFGQTKFIVSHYAVDVEYEVEGFIEKNRDSVSLGHLDVFKAT</Hsp_hseq>
      <Hsp_midline>NP IL   +DLT LSYL+EPAVLH +K R+  +  IYTY GIVL+A NP++++  +Y  ++I  YS +   +++PH+FA+AEEAY+ M  ++ NQ+++VSGESGAGKTVSAKY MRYFA+V       G    + IE ++LA+NPIME  G           N+K+    NSSRFGKY++I F+    I G+ +RTYLLEKSR+V+Q                                + YT QGG   I  +D+  + + T  A +L+GI    Q+GIFKI+AG+LH+GN+E++    +     ++ E+++L I CELLG++    A W+  ++I T +E  V  +   QA  ARD++AK +Y+ LF W+ +D +++ +   ++  +   F+     +                  FE FE NSFEQFCINYANEKLQQ+FN HVFKLEQEEY++EEI W+ I+F DNQPCIDLIE KLG+L LLDEE ++P GSD+SWA KLY         + F KPR     FI+ H+A  VEY+ +GF+EKNRD+V    +++ KA+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>134.42</Hsp_bit-score>
      <Hsp_score>337</Hsp_score>
      <Hsp_evalue>1.0544e-31</Hsp_evalue>
      <Hsp_query-from>1597</Hsp_query-from>
      <Hsp_query-to>2331</Hsp_query-to>
      <Hsp_hit-from>676</Hsp_hit-from>
      <Hsp_hit-to>931</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>84</Hsp_identity>
      <Hsp_positive>129</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>256</Hsp_align-len>
      <Hsp_qseq>FDPKRAVQQLRACGVLETIRLSAAGYPSRWTYQEFFNRYRVL---------MRKKDIVSDDKKQTVQNVLEHVIKDPDKFQFGKTKIFFRAGQVAYLEKLRADKLRAACIKMQKTIRGWLQRKRYLRMRAAAITIQRHVRGHQARRLAQFMRSTRAAVIIQTXXXXXXXXXXXXKIRRTAIRMQARARGIFARQRYQQMLYRHKAVVLQKHVRGWLARRLVQRELHAVVHLQCCVRRMRARRQ--LKQLRIEARSV</Hsp_qseq>
      <Hsp_hseq>FDNLMVLSQLRACGVLETIRISCAGFPSRWTFDEFVQRYFLLTDYSLWSGILYNPDLPKEAIVNFCQSILDATISDSAKYQIGNTKIFFKAGMLAFLEKLRTNKMNEICIIIQKKIRARYYRLQYLQTMESIKKCQSQIRSLLVRTRVDHELKTRAAILLQTNIRALWKREYYRAAIGQIIKLQCTCKRKLILDSVNRKFMLMAAVIIQSYIRSYGHKTDYRTLKRSSILVQSAMRMQLARRRYIVLQKEVEERNI</Hsp_hseq>
      <Hsp_midline>FD    + QLRACGVLETIR+S AG+PSRWT+ EF  RY +L         +   D+  +      Q++L+  I D  K+Q G TKIFF+AG +A+LEKLR +K+   CI +QK IR    R +YL+   +    Q  +R    R        TRAA+++QT  R    R  Y       I++Q   +         +      AV++Q ++R +  +   +    + + +Q  +R   ARR+  + Q  +E R++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YMR109W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:486587:490246:1 gene:YMR109W transcript:YMR109W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MYO5 description:One of two type I myosin motors; contains proline-rich tail homology 2 (TH2) and SH3 domains; MYO5 deletion has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization; MYO5 has a paralog, MYO3, that arose from the whole genome duplication [Source:SGD;Acc:S000004715]</Hit_def>
  <Hit_accession>YMR109W</Hit_accession>
  <Hit_len>1219</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>305.449</Hsp_bit-score>
      <Hsp_score>781</Hsp_score>
      <Hsp_evalue>2.42429e-85</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>1989</Hsp_query-to>
      <Hsp_hit-from>36</Hsp_hit-from>
      <Hsp_hit-to>748</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>235</Hsp_identity>
      <Hsp_positive>353</Hsp_positive>
      <Hsp_gaps>148</Hsp_gaps>
      <Hsp_align-len>758</Hsp_align-len>
      <Hsp_qseq>VGENDLTALSYLHEPAVLHNLKVRFAESNHIYTYCGIVLVAINPYEQLPIYGEDIIFAYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASEA--NIEEKVLASNPIMERHGCLYSASPAEHLNSKSQGNSSRFGKYIEIGFNRQYLIVGANMRTYLLEKSRVVFQ-------------------------------AFVYTAQGGNAVIEDVDDGEDLERTRRAFTLLGIGASYQMGIFKIIAGILHLGNVEVQSQDREQETCFVNKEDKHLNIFCE-LLGLERDQMAHWLCHRKISTG-----AETYVKPMGRTQAQNARDALAKHVYAQLFSWIEMDGLHQAIDLGKVVSRWQAFNVDEARNDXXXXXXXXXXXXXPPNRFETFEINSFEQFCINYANEKLQQQFNLHVFKLEQEEYMREEIPWTLIDFYDNQPCIDLIEAK--LGVLDLLDEECKM----PKGSDQSWAQKLYEKHLGRGKHFLKPRMSNVAFIICHFADKVEYQCDGFLEKNRD-------------------TVYEEQIN-------------ILKA--------SQVRPAR-RTFDP-----------KRAVQQLRACGVLETIRLSAAGYPSRWTYQEFFNRYRVLMRKKDIVSD-----DKKQTVQNVLEHVIKDPDKFQFGKTKIFFRAGQVAY-LEKLRADKLRAACIKMQKTIRGWLQRKRYLRMRAAAITIQRHVR</Hsp_qseq>
      <Hsp_hseq>VGVSDLTLLSKISDEAINENLKKRFLNAT-IYTYIGHVLISVNPFRDLGIYTDAVMNEYKGKNRLEVPPHVFAIAESMYYNMKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASSTHTESIGKIKDMVLATNPLLESFGC------AKTLRN---NNSSRHGKYLEIKFNNQFEPCAGNITNYLLEKQRVVSQIKNERNFHIFYQFTKGASDAYRQTFGVQKPEQYVYTAAAGCISAETIDDLQDYQETLKAMRVIGLGQEEQDQIFRMLAAILWIGNVSFI----ENEEGNAQVRDTSVTDFVAYLLQIDSQLLIKSLVERIMETNHGMKRGSVYHVPLNIVQADAVRDALAKAIYNNLFDWI----------VSRVNKSLQAFPGAEKSIGILDIYG-----------FEIFEHNSFEQICINYVNEKLQQIFIQLTLKSEQETYEREKIQWTPIKYFDNKVVCDLIEARRPPGIFAAMNDSVATAHADSNAADQAFAQRL--NLFTTNPHF---DLRSNKFVIKHYAGDVTYDIDGITDKNKDQLQKDLVELIGTTTNTFLATIFPDTVDRESKRRPPTAGDKIIKSANDLVETLSKAQPSYIRTIKPNETKSPNDYDDRQVLHQIKYLGLQENVRIRRAGFAYRQVFEKFVERFYLLSPHCSYAGDYTWQGDTLDAVKYILQDSSIPQQEYQLGVTSVFIKTPETLFALEHMRDRYWHNMAARIQRAWRRFLQRR-----IDAATKIQRTIR</Hsp_hseq>
      <Hsp_midline>VG +DLT LS + + A+  NLK RF  +  IYTY G VL+++NP+  L IY + ++  Y G+N  ++ PH+FA+AE  Y  M    +NQ +I+SGESGAGKT +AK  M+Y A    + +E+   I++ VLA+NP++E  GC      A+ L +    NSSR GKY+EI FN Q+     N+  YLLEK RVV Q                                +VYTA  G    E +DD +D + T +A  ++G+G   Q  IF+++A IL +GNV       E E       D  +  F   LL ++   +   L  R + T         Y  P+   QA   RDALAK +Y  LF WI          + +V    QAF   E    ++ +             FE FE NSFEQ CINY NEKLQQ F     K EQE Y RE+I WT I ++DN+   DLIEA+   G+   +++           +DQ++AQ+L         HF    + +  F+I H+A  V Y  DG  +KN+D                   T++ + ++             I+K+        S+ +P+  RT  P           ++ + Q++  G+ E +R+  AG+  R  +++F  R+ +L        D     D    V+ +L+       ++Q G T +F +  +  + LE +R         ++Q+  R +LQR+       AA  IQR +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YKL129C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:196349:200167:-1 gene:YKL129C transcript:YKL129C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MYO3 description:One of two type I myosins; localizes to actin cortical patches; deletion of MYO3 has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization; MYO3 has a paralog, MYO5, that arose from the whole genome duplication [Source:SGD;Acc:S000001612]</Hit_def>
  <Hit_accession>YKL129C</Hit_accession>
  <Hit_len>1272</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>303.523</Hsp_bit-score>
      <Hsp_score>776</Hsp_score>
      <Hsp_evalue>1.52402e-84</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>1989</Hsp_query-to>
      <Hsp_hit-from>36</Hsp_hit-from>
      <Hsp_hit-to>748</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>237</Hsp_identity>
      <Hsp_positive>353</Hsp_positive>
      <Hsp_gaps>150</Hsp_gaps>
      <Hsp_align-len>759</Hsp_align-len>
      <Hsp_qseq>VGENDLTALSYLHEPAVLHNLKVRFAESNHIYTYCGIVLVAINPYEQLPIYGEDIIFAYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASEA--NIEEKVLASNPIMERHGCLYSASPAEHLNSKSQGNSSRFGKYIEIGFNRQYLIVGANMRTYLLEKSRVVFQA-------------------------------FVYTAQGGNAVIEDVDDGEDLERTRRAFTLLGIGASYQMGIFKIIAGILHLGNVEVQSQDREQETCFVNKEDKHLNIFCE-LLGLERDQMAHWLCHRKISTG-----AETYVKPMGRTQAQNARDALAKHVYAQLFSWIEMDGLHQAIDLGKVVSRWQAF-NVDEARNDXXXXXXXXXXXXXPPNRFETFEINSFEQFCINYANEKLQQQFNLHVFKLEQEEYMREEIPWTLIDFYDNQPCIDLIEAK--LGVLDLLDEECKM----PKGSDQSWAQKLYEKHLGRGKHFLKPRMSNVAFIICHFADKVEYQCDGFLEKNRDTVYEEQINIL-----------------KASQVRPAR------------------------RTFDPKRA-----------VQQLRACGVLETIRLSAAGYPSRWTYQEFFNRYRVLMRKKDIVSD-----DKKQTVQNVLEHVIKDPDKFQFGKTKIFFRAGQVAY-LEKLRADKLRAACIKMQKTIRGWLQRKRYLRMRAAAITIQRHVR</Hsp_qseq>
      <Hsp_hseq>VGISDLTLLSKISDESINENLKKRF-KNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKIKDMVLATNPLLESFGC------AKTLRN---NNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISFI----ENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWI----------VDRVNVSLQAFPGADKSIGILDIYG------------FEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRL---NLFNSNPYFELRANK--FVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRR-----IDAAIKIQRTIR</Hsp_hseq>
      <Hsp_midline>VG +DLT LS + + ++  NLK RF ++  IYTY G VL+++NP+  L IY   ++ +Y G+N  ++ PH+FA+AE  Y  +    +NQ +I+SGESGAGKT +AK  M+Y A    S SE+   I++ VLA+NP++E  GC      A+ L +    NSSR GKY+EI FN Q+     N+  YLLEK RVV Q                                ++YTA  G    + +DD +D E T  A   +G+    Q  IF+++A IL +GN+       E E       D  +  F   LL ++   +   L  R + T         Y  P+   QA   RDALAK +Y  LF WI          + +V    QAF   D++   + I              FE FE NSFEQ CINY NEKLQQ F     K EQE Y RE+I WT I ++DN+   DLIEAK   G+L  +++           +DQ++AQ+L   +L     + + R +   F+I H+A  V Y  +G  +KN+D + ++ I ++                 K S+ RP                          RT  P +            + Q++  G+ E +R+  AG+  R T+++F  R+ +L        D     D  + V+ +L   +    +FQ G T +F +  +  + LE +R         ++Q+  R +LQR+       AAI IQR +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YHR023W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:151666:157452:1 gene:YHR023W transcript:YHR023W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MYO1 description:Type II myosin heavy chain; required for wild-type cytokinesis and cell separation; localizes to the actomyosin ring; binds to myosin light chains Mlc1p and Mlc2p through its IQ1 and IQ2 motifs respectively [Source:SGD;Acc:S000001065]</Hit_def>
  <Hit_accession>YHR023W</Hit_accession>
  <Hit_len>1928</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>301.597</Hsp_bit-score>
      <Hsp_score>771</Hsp_score>
      <Hsp_evalue>9.32558e-83</Hsp_evalue>
      <Hsp_query-from>10</Hsp_query-from>
      <Hsp_query-to>1608</Hsp_query-to>
      <Hsp_hit-from>70</Hsp_hit-from>
      <Hsp_hit-to>625</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>201</Hsp_identity>
      <Hsp_positive>302</Hsp_positive>
      <Hsp_gaps>97</Hsp_gaps>
      <Hsp_align-len>593</Hsp_align-len>
      <Hsp_qseq>NPDILVGENDLTALSYLHEPAVLHNLKVRFAESNHIYTYCGIVLVAINPYEQLPIYGEDIIFAYSGQ------------NMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFAT-----------VGGSASEANIEEKVLASNPIMERHGCLYSASPAEHLNSKSQGNSSRFGKYIEIGFNRQYLIVGANMRTYLLEKSRVVFQA---------------------------------FVYTAQGGNAVIEDVDDGEDLERTRRAFTLLGIGASYQMGIFKIIAGILHLGNVEVQSQDREQETCFVNKEDKHLNIFCELLGLERDQMAHWLCHRKISTGAETYVKPMGRTQAQNARDALAKHVYAQLFSWIEMDGLHQAIDLGKVVSRWQAFNVDEARNDXXXXXXXXXXXXXPPNRFETFEINSFEQFCINYANEKLQQQFNLHVFKLEQEEYMREEIPWTLIDF-YDNQPCIDLIEAK---LGVLDLLDEECKMPKGSDQSWAQKLYEKHLGRGKHFLKPRMSNVAFIICHFADKVEYQCDGFLEKNRDTVYEEQINILKASQVRPARRTFDPK</Hsp_qseq>
      <Hsp_hseq>NPSTFDKVENMSELTHLNEPSVLYNLEKRY-DCDLIYTYSGLFLVAINPYHNLNLYSEDHINLYHNKHNRLSKSRLDENSHEKLPPHIFAIAEEAYENLLSEGKDQSILVTGESGAGKTENTKKILQYLASITSGSPSNIAPVSGSSIVESFEMKILQSNPILESFGNAQTV---------RNNNSSRFGKFIKIEFNEHGMINGAHIEWYLLEKSRIVHQNSKERNYHIFYQLLSGLDDSELKNLRLKSRNVKDYKILSNSNQDIIPGINDVENFKELLSALNIIGFSKDQIRWIFQVVAIILLIGNIEFVS-DRAEQASFKN----DVSAICSNLGVDEKDFQTAILRPRSKAGKEWVSQSKNSQQAKFILNALSRNLYERLFGYI-VDMINKNLDHGSATLNYIGL-LDIA-------------------GFEIFENNSFEQLCINYTNEKLQQFFNNHMFVLEQSEYLKENIQWDYIDYGKDLQLTIDLIESKGPPTGVLPLLDEEAVLPKSTDESFYSKLISTWDQNSSKFKRSRLKN-GFILKHYAGDVEYTVEGWLSKNKDPLNDNLLSLLSSSQNDIISKLFQPE</Hsp_hseq>
      <Hsp_midline>NP       +++ L++L+EP+VL+NL+ R+ + + IYTY G+ LVAINPY  L +Y ED I  Y  +            +   + PHIFA+AEEAY+ +  + K+QSI+V+GESGAGKT + K  ++Y A+           V GS+   + E K+L SNPI+E  G   +             NSSRFGK+I+I FN   +I GA++  YLLEKSR+V Q                                  +   +     +I  ++D E+ +    A  ++G        IF+++A IL +GN+E  S DR ++  F N     ++  C  LG++       +   +   G E   +     QA+   +AL++++Y +LF +I +D +++ +D G     +    +D A                    FE FE NSFEQ CINY NEKLQQ FN H+F LEQ EY++E I W  ID+  D Q  IDLIE+K    GVL LLDEE  +PK +D+S+  KL          F + R+ N  FI+ H+A  VEY  +G+L KN+D + +  +++L +SQ     + F P+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>88.1965</Hsp_bit-score>
      <Hsp_score>217</Hsp_score>
      <Hsp_evalue>1.14001e-17</Hsp_evalue>
      <Hsp_query-from>1591</Hsp_query-from>
      <Hsp_query-to>1938</Hsp_query-to>
      <Hsp_hit-from>690</Hsp_hit-from>
      <Hsp_hit-to>812</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>123</Hsp_align-len>
      <Hsp_qseq>RTFDPKRAVQQLRACGVLETIRLSAAGYPSRWTYQEFFNRYRVLMRKKDIVSD-------DKKQTVQNVLEHVIKDPDKFQFGKTKIFFRAGQVAYLEKLRADKLRAACIKMQKTIRGWLQRK</Hsp_qseq>
      <Hsp_hseq>KTFNRRLILDQLRCNGVLEGIRLAREGYPNRIAFQEFFQRYRILYPENSTTTTFSSKLKASTKQNCEFLLTSLQLDTKVYKIGNTKLFFKAGVLADLEKQKDVKLNNIMIKLTATIRGYTVRK</Hsp_hseq>
      <Hsp_midline>+TF+ +  + QLR  GVLE IRL+  GYP+R  +QEFF RYR+L  +    +          KQ  + +L  +  D   ++ G TK+FF+AG +A LEK +  KL    IK+  TIRG+  RK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>105</Statistics_hsp-len>
      <Statistics_eff-space>4446576134</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052658-RA transcript Note:&quot;Similar to cfap53 Cilia- and flagella-associated protein 53 (Danio rerio)&quot; offset:208 AED:0.29 eAED:0.38 QI:208|0.66|0.57|1|0.83|0.71|7|0|442</Iteration_query-def>
  <Iteration_query-len>1537</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>958752806</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052659-RA transcript Note:&quot;Similar to ATP8B2 Phospholipid-transporting ATPase ID (Homo sapiens)&quot; offset:0 AED:0.20 eAED:0.20 QI:0|0.45|0.47|0.61|0.9|0.95|21|1361|975</Iteration_query-def>
  <Iteration_query-len>4289</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YAL026C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:95630:99697:-1 gene:YAL026C transcript:YAL026C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DRS2 description:Trans-golgi network aminophospholipid translocase (flippase); maintains membrane lipid asymmetry in post-Golgi secretory vesicles; contributes to clathrin-coated vesicle formation, endocytosis, protein trafficking between the Golgi and endosomal system and the cellular response to mating pheromone; autoinhibited by its C-terminal tail; localizes to the trans-Golgi network; mutations in human homolog ATP8B1 result in liver disease [Source:SGD;Acc:S000000024]</Hit_def>
  <Hit_accession>YAL026C</Hit_accession>
  <Hit_len>1355</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>283.108</Hsp_bit-score>
      <Hsp_score>723</Hsp_score>
      <Hsp_evalue>2.69635e-78</Hsp_evalue>
      <Hsp_query-from>805</Hsp_query-from>
      <Hsp_query-to>2484</Hsp_query-to>
      <Hsp_hit-from>623</Hsp_hit-from>
      <Hsp_hit-to>1285</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>215</Hsp_identity>
      <Hsp_positive>324</Hsp_positive>
      <Hsp_gaps>119</Hsp_gaps>
      <Hsp_align-len>671</Hsp_align-len>
      <Hsp_qseq>VHEFFRLLALCHTVMPEEKTEGELAYQAQSPDEGALVTAARNFDFVFRSRTPETIT--LHELGEPRTYQLLAILDFNNFRKRMSVIVRNAEGRLKLYCKGADSVIFERLHPCNQQLVNITADHLSAFAGEGLRTLCLAYRDLDEASFEEWQERHHEANTSLQGREELLAAVYDEIEQNMMLLGATAIEDKLQE------------------------ETAVNIGYSCNML----------------------------------TDDMNEV-FVVSGHTVQEVRE-----------ELGRA----------KAKMLGLSKGSAANGFLYSSVKDPSKACPSIETTVEG---DGQEGMQAVLSSDYSFAXXXXXXXXXXVHGRWSYLRMCKFLCYFFYKNFAFTLT--------------VYDQWFITLFNIVYTSLPVLAMGVFDQDINDQWSIDCPKLYEPGQLNLLFNKREFFICIGQGIYTSVVLFFVPYAAFVEAVRDDGTG-LSDHQSLAVAVSTSLIIVVSLQMGLDTAYWTAINHFFIWGSVAVYFAIMFAMYSAGLYSIFPS---QFRFIGTARNTLNQPSVWLVIALTTIVCIMPIAAFRFLKTDLRP----TLSDKERYMQRQRRKQKPQ----TLRLHRVHRTGSRRSGYAFAHQEGFGE</Hsp_qseq>
      <Hsp_hseq>INDFLTLLATCHTVIPEFQSDGSIKYQAASPDEGALVQGGADLGYKFIIRKPNSVTVLLEETGEEKEYQLLNICEFNSTRKRMSAIFRFPDGSIKLFCKGADTVILERLDDEANQYVEATMRHLEDYASEGLRTLCLAMRDISEGEYEEWNSIYNEAATTLDNRAEKLDEAANLIEKNLILIGATAIEDKLQDGVPETIHTLQEAGIKIWVLTGDRQETAINIGMSCRLLSEDMNLLIINEETRDDTERNLLEKINALNEHQLSTHDMNTLALVIDGKSLGFALEPELEDYLLTVAKLCKAVICCRVSPLQKALVVKMVKRKSSSLLL--AIGDGANDVSMIQAAHVGVGISGMEGMQAARSADIAVGQFKFLKKLLLVHGSWSYQRISVAILYSFYKNTALYMTQFWYVFANAFSGQSIMESWTMSFYNLFFTVWPPFVIGVFDQFVSSRLLERYPQLYKLGQKGQFFSVYIFWGWIINGFFHSAIVFIGTILIYRYGFALNMHGELADHWSWGVTVYTTSVIIVLGKAALVTNQWTKFTLIAIPGSL-LFWLIFFPIYA----SIFPHANISREYYGVVKHTYGSGVFWLTLIVLPIFALVRDFLWKYYKRMYEPETYHVIQEMQKYNISDSRPHVQQFQNAIRKVRQVQRMKKQR-GFAFSQAEEGGQ</Hsp_hseq>
      <Hsp_midline>+++F  LLA CHTV+PE +++G + YQA SPDEGALV    +  + F  R P ++T  L E GE + YQLL I +FN+ RKRMS I R  +G +KL+CKGAD+VI ERL     Q V  T  HL  +A EGLRTLCLA RD+ E  +EEW   ++EA T+L  R E L    + IE+N++L+GATAIEDKLQ+                        ETA+NIG SC +L                                  T DMN +  V+ G ++    E           +L +A          KA ++ + K  +++  L  ++ D +     I+    G    G EGMQA  S+D +  QF+FL++LLLVHG WSY R+   + Y FYKN A  +T              + + W ++ +N+ +T  P   +GVFDQ ++ +     P+LY+ GQ    F+   F+  I  G + S ++F      +      +  G L+DH S  V V T+ +I+V  +  L T  WT      I GS+ +++ I F +Y+    SIFP       + G  ++T      WL + +  I  ++    +++ K    P     + + ++Y     R    Q      ++ +V R   +R G+AF+  E  G+</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>135.191</Hsp_bit-score>
      <Hsp_score>339</Hsp_score>
      <Hsp_evalue>3.37139e-32</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>201</Hsp_hit-from>
      <Hsp_hit-to>514</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>97</Hsp_identity>
      <Hsp_positive>150</Hsp_positive>
      <Hsp_gaps>98</Hsp_gaps>
      <Hsp_align-len>317</Hsp_align-len>
      <Hsp_qseq>NRIKTSKYNVVTFLPVNLFEQFQRVANAYFL----------------------FLLILQF-----------RHRSDNQVNNRQSQV--HINGKLQNEKWMNVRVGDIIKMENNQFVAADXXXXXXXEPHSLCYIETAELDG----------------------------------------FTGTLYWRGNTYSLDNDKMLLRGCVLRNTEWCYGLVVFAGPDTKLMQNSGRTKLKRTSIDRLMN-----------TLVLWSAIGYYFQ--------PYLPWESAVDSAI-FSGFLTFWSYIIILNTVVPISLYVSL</Hsp_qseq>
      <Hsp_hseq>NHISTTKYNFATFLPKFLFQEFSKYANLFFLCTSAIQQVPHVSPTNRYTTIGTLLVVLIVSAMKECIEDIKRANSDKELNNSTAEIFSEAHDDFVEKRWIDIRVGDIIRVKSEEPIPADTIILSSSEPEGLCYIETANLDGETNLKIKQSRVETAKFIDVKTLKNMNGKVVSEQPNSSLYTYEGTMTLNDRQIPLSPDQMILRGATLRNTAWIFGLVIFTGHETKLLRNATATPIKRTAVEKIINRQIIALFTVLIVLILISSIGNVIMSTADAKHLSYLYLEGTNKAGLFFKDFLTFW---ILFSNLVPISLFVTV</Hsp_hseq>
      <Hsp_midline>N I T+KYN  TFLP  LF++F + AN +FL                       L++L             R  SD ++NN  +++    +     ++W+++RVGDII++++ + + AD ++LSSSEP  LCYIETA LDG                                        + GT+        L  D+M+LRG  LRNT W +GLV+F G +TKL++N+  T +KRT++++++N            L+L S+IG             YL  E    + + F  FLTFW   I+ + +VPISL+V++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YDR093W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:631282:636120:1 gene:YDR093W transcript:YDR093W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DNF2 description:Aminophospholipid translocase (flippase); type 4 P-type ATPase; involved in phospholipid translocation, contributing to endocytosis, protein transport, and cellular polarization; localizes primarily to the plasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; DNF2 has a paralog, DNF1, that arose from the whole genome duplication [Source:SGD;Acc:S000002500]</Hit_def>
  <Hit_accession>YDR093W</Hit_accession>
  <Hit_len>1612</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>253.832</Hsp_bit-score>
      <Hsp_score>647</Hsp_score>
      <Hsp_evalue>8.43877e-69</Hsp_evalue>
      <Hsp_query-from>757</Hsp_query-from>
      <Hsp_query-to>2307</Hsp_query-to>
      <Hsp_hit-from>791</Hsp_hit-from>
      <Hsp_hit-to>1435</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>199</Hsp_identity>
      <Hsp_positive>309</Hsp_positive>
      <Hsp_gaps>144</Hsp_gaps>
      <Hsp_align-len>653</Hsp_align-len>
      <Hsp_qseq>FYDQTMLEAIRLGEWGVHE------FFRLLALCHTVM--PEEKTEGELAYQAQSPDEGALVTAARNFDFVFRSRTPETITLHELGEPRTYQLLAILDFNNFRKRMSVIVR------NAEGRLKLYCKGADSVIFERLHPCNQQ--LVNITADHLSAFAGEGLRTLCLAYRDLDEASFEEWQERHHEANTSLQGREELLAAVYDEIEQNMMLLGATAIEDKLQE------------------------ETAVNIGYSCNMLTDDMNEVFVV--SGHTVQE----------------VREELG--------RAKAKMLGLSKGS------------AANG------FLY------------------SSVKDPSKACPSIETTVEGDGQEGMQAVLSS------------------DYSFAXXXXXXXXXXVHGRWSYLRMCKFLCYFFYKNFAFTLT-----VYDQW---------FITLFNIVYTSLPVLAMGVFDQDINDQWSIDCPKLYEPGQLNLLFNKREFFICIGQGIYTSVVLFFVPYAAFVE--AVRDDGTGLSDHQSLAVAVSTSLIIVVSLQMGLDTAYWTAINHFFIWGSVAVYFAIMFAMYSAGLYSIFPSQFRFIGTARNTLNQPSVWLVIALTTIVCIMP</Hsp_qseq>
      <Hsp_hseq>FVSKEIVEDLK-GSSGDHQQKCCEHFLLALALCHSVLVEPNKDDPKKLDIKAQSPDESALVSTARQLGYSFVGSSKSGLIVEIQGVQKEFQVLNVLEFNSSRKRMSCIIKIPGSTPKDEPKALLICKGADSVIYSRLDRTQNDATLLEKTALHLEEYATEGLRTLCLAQRELTWSEYERWVKTYDVAAASVTNREEELDKVTDVIERELILLGGTAIEDRLQDGVPDSIALLAEAGIKLWVLTGDKVETAINIGFSCNVLNNDM-ELLVVKASGEDVEEFGSDPIQVVNNLVTKYLREKFGMSGSEEELKEAKREHGLPQGNFAVIIDGDALKVALNGEEMRRKFLLLCKNCKAVLCCRVSPAQKAAVVKLVKKTLDVMTLAIGDGSNDVAMIQSADVGVGIAGEEGRQAVMCSDYAIGQFRYVTRLVLVHGKWCYKRLAEMIPQFFYKNVIFTLSLFWYGIYNNFDGSYLFEYTYLTFYNLAFTSVPVILLAVLDQDVSDTVSMLVPQLYRVGILRKEWNQTKFLWYMLDGVYQSVICFFFPYLAYHKNMVVTENGLGLDHRYFVGVFVTAIAVTSCNFYVFMEQYRWDWFCGLFICLSLAVFYGW------TGIWTSSSSSNEFYKGAARVFAQPAYWAVLFVGVLFCLLP</Hsp_hseq>
      <Hsp_midline>F  + ++E ++ G  G H+      F   LALCH+V+  P +    +L  +AQSPDE ALV+ AR   + F   +   + +   G  + +Q+L +L+FN+ RKRMS I++        E +  L CKGADSVI+ RL        L+  TA HL  +A EGLRTLCLA R+L  + +E W + +  A  S+  REE L  V D IE+ ++LLG TAIED+LQ+                        ETA+NIG+SCN+L +DM E+ VV  SG  V+E                +RE+ G        +   +  GL +G+            A NG      FL                   ++V    K    + T   GDG   +  + S+                  DY+  QFR++ RL+LVHG+W Y R+ + +  FFYKN  FTL+     +Y+ +         ++T +N+ +TS+PV+ + V DQD++D  S+  P+LY  G L   +N+ +F   +  G+Y SV+ FF PY A+ +   V ++G GL     + V V+   +   +  + ++   W      FI  S+AV++         G+++   S   F   A     QP+ W V+ +  + C++P</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>108.227</Hsp_bit-score>
      <Hsp_score>269</Hsp_score>
      <Hsp_evalue>5.49994e-24</Hsp_evalue>
      <Hsp_query-from>118</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>418</Hsp_hit-from>
      <Hsp_hit-to>666</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>119</Hsp_positive>
      <Hsp_gaps>65</Hsp_gaps>
      <Hsp_align-len>249</Hsp_align-len>
      <Hsp_qseq>RHRSDNQVNNRQSQVHINGKLQNEKWMNVRVGDIIKMENNQFVAADXXXXXXXEPHSLCYIETAELDG---------------------FTGTLYW------RGNTYS-------------------LDNDKMLLRGCVLRNTEWCYGLVVFAGPDTKLMQNSGRTKLKRTSIDRLMNTLVLWSAI-------------GYYFQ------PYLPWESAVDSAIFSGFLTFWSYIIILNTVVPISLYVSL</Hsp_qseq>
      <Hsp_hseq>RYNDGENLVDRTLQPNPECRFAKDYWKNVKVGDIVRVHNNDEIPADMILLSTSDVDGACYVETKNLDGETNLKVRQSLKCSKIIKSSRDITRTKFWVESEGPHANLYSYQGNFKWQDTQNGNIRNEPVNINNLLLRGCTLRNTKWAMGMVIFTGDDTKIMINAGVTPTKKSRISRELNFSVILNFVLLFILCFTAGIVNGVYYKQKPRSRDYFEFGTIGGSASTNGFVSFWVAVILYQSLVPISLYISV</Hsp_hseq>
      <Hsp_midline>R+     + +R  Q +   +   + W NV+VGDI+++ NN  + AD++LLS+S+    CY+ET  LDG                      T T +W        N YS                   ++ + +LLRGC LRNT+W  G+V+F G DTK+M N+G T  K++ I R +N  V+ + +             G Y++       Y  + +   SA  +GF++FW  +I+  ++VPISLY+S+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YER166W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:512744:517459:1 gene:YER166W transcript:YER166W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DNF1 description:Aminophospholipid translocase (flippase); type 4 P-type ATPase; involved in phospholipid translocation, contributing to endocytosis, protein transport, and cellular polarization; localizes primarily to the plasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; DNF1 has a paralog, DNF2, that arose from the whole genome duplication [Source:SGD;Acc:S000000968]</Hit_def>
  <Hit_accession>YER166W</Hit_accession>
  <Hit_len>1571</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>171.4</Hsp_bit-score>
      <Hsp_score>433</Hsp_score>
      <Hsp_evalue>2.56494e-43</Hsp_evalue>
      <Hsp_query-from>808</Hsp_query-from>
      <Hsp_query-to>1479</Hsp_query-to>
      <Hsp_hit-from>768</Hsp_hit-from>
      <Hsp_hit-to>1028</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>103</Hsp_identity>
      <Hsp_positive>149</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>262</Hsp_align-len>
      <Hsp_qseq>HEFFRLLALCHTVMPEEKTEG--ELAYQAQSPDEGALVTAARNFDFVFRSRTPETITLHELGEPRTYQLLAILDFNNFRKRMSVIVR------NAEGRLKLYCKGADSVIFERLH----PCNQQLVNITADHLSAFAGEGLRTLCLAYRDLDEASFEEWQERHHEANTSLQGREELLAAVYDEIEQNMMLLGATAIEDKLQE------------------------ETAVNIGYSCNMLTDDMNEVFVV--SGHTVQEVREE</Hsp_qseq>
      <Hsp_hseq>EHFMLALALCHSVLVEANPDNPKKLDLKAQSPDEAALVATARDVGFSFVGKTKKGLIIEMQGIQKEFEILNILEFNSSRKRMSCIVKIPGLNPGDEPRALLICKGADSIIYSRLSRQSGSNSEAILEKTALHLEQYATEGLRTLCIAQRELSWSEYEKWNEKYDIAAASLANREDELEVVADSIERELILLGGTAIEDRLQDGVPDCIELLAEAGIKLWVLTGDKVETAINIGFSCNLLNNEM-ELLVIKTTGDDVKEFGSE</Hsp_hseq>
      <Hsp_midline>  F   LALCH+V+ E   +   +L  +AQSPDE ALV  AR+  F F  +T + + +   G  + +++L IL+FN+ RKRMS IV+        E R  L CKGADS+I+ RL       ++ ++  TA HL  +A EGLRTLC+A R+L  + +E+W E++  A  SL  RE+ L  V D IE+ ++LLG TAIED+LQ+                        ETA+NIG+SCN+L ++M E+ V+  +G  V+E   E</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>134.035</Hsp_bit-score>
      <Hsp_score>336</Hsp_score>
      <Hsp_evalue>6.65359e-32</Hsp_evalue>
      <Hsp_query-from>1606</Hsp_query-from>
      <Hsp_query-to>2349</Hsp_query-to>
      <Hsp_hit-from>1149</Hsp_hit-from>
      <Hsp_hit-to>1406</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>88</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>264</Hsp_align-len>
      <Hsp_qseq>GQEGMQAVLSSDYSFAXXXXXXXXXXVHGRWSYLRMCKFLCYFFYKNFAFTLTV--------------YDQWFITLFNIVYTSLPVLAMGVFDQDINDQWSIDCPKLYEPGQLNLLFNKREFFICIGQGIYTSVVLFFVPYAAFVE--AVRDDGTGLSDHQSLAVAVSTSLIIVVSLQMGLDTAYWTAINHFFIWGSVAVYFAIMFAMYSAGLYSIFPSQFRFIGTARNTLNQPSVWLVIALTTIVCIMPIAAFRFLKTDLRPT</Hsp_qseq>
      <Hsp_hseq>GEEGRQAVMCSDYAIGQFRYLARLVLVHGRWSYKRLAEMIPEFFYKNMIFALALFWYGIYNDFDGSYLYEYTYMMFYNLAFTSLPVIFLGILDQDVNDTISLVVPQLYRVGILRKEWNQRKFLWYMLDGLYQSIICFFFPYLVYHKNMIVTSNGLGLDHRYFVGVYVTTIAVISCNTYVLLHQYRWDWFSGLFIALSCLVVFAW------TGIWSSAIASREFFKAAARIYGAPSFWAVFFVAVLFCLLPRFTYDSFQKFFYPT</Hsp_hseq>
      <Hsp_midline>G+EG QAV+ SDY+  QFR+L RL+LVHGRWSY R+ + +  FFYKN  F L +              Y+  ++  +N+ +TSLPV+ +G+ DQD+ND  S+  P+LY  G L   +N+R+F   +  G+Y S++ FF PY  + +   V  +G GL     + V V+T  +I  +  + L    W   +  FI  S  V FA        G++S   +   F   A      PS W V  +  + C++P   +   +    PT</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>99.3673</Hsp_bit-score>
      <Hsp_score>246</Hsp_score>
      <Hsp_evalue>2.54449e-21</Hsp_evalue>
      <Hsp_query-from>175</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>392</Hsp_hit-from>
      <Hsp_hit-to>621</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>65</Hsp_gaps>
      <Hsp_align-len>230</Hsp_align-len>
      <Hsp_qseq>KLQNEKWMNVRVGDIIKMENNQFVAADXXXXXXXEPHSLCYIETAELDG----------------------------------------FTGTLYWRG------NTYSLDNDKMLLRGCVLRNTEWCYGLVVFAGPDTKLMQNSGRTKLKRTSIDRLMNTLVLWS-------------AIGYYFQPY------LPWESAVDSAIFSGFLTFWSYIIILNTVVPISLYVSL</Hsp_qseq>
      <Hsp_hseq>KFAKNYWKGVKVGDIVRIHNNDEIPADIILLSTSDTDGACYVETKNLDGETNLKVRQSLKCTNTIRTSKDIARTKFWIESEGPHSNLYTYQGNMKWRNLADGEIRNEPITINNVLLRGCTLRNTKWAMGVVMFTGGDTKIMLNSGITPTKKSRISRELNFSVVINFVLLFILCFVSGIANGVYYDKKGRSRFSYEFGTIAGSAATNGFVSFWVAVILYQSLVPISLYISV</Hsp_hseq>
      <Hsp_midline>K     W  V+VGDI+++ NN  + AD++LLS+S+    CY+ET  LDG                                        + G + WR           +  + +LLRGC LRNT+W  G+V+F G DTK+M NSG T  K++ I R +N  V+ +             A G Y+           + +   SA  +GF++FW  +I+  ++VPISLY+S+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YIL048W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:261437:264892:1 gene:YIL048W transcript:YIL048W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NEO1 description:Phospholipid translocase (flippase), role in phospholipid asymmetry of plasma membrane; involved in endocytosis, vacuolar biogenesis and Golgi to ER vesicle-mediated transport; localizes to endosomes and the Golgi apparatus [Source:SGD;Acc:S000001310]</Hit_def>
  <Hit_accession>YIL048W</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>139.813</Hsp_bit-score>
      <Hsp_score>351</Hsp_score>
      <Hsp_evalue>9.02806e-34</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>1473</Hsp_query-to>
      <Hsp_hit-from>172</Hsp_hit-from>
      <Hsp_hit-to>782</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>155</Hsp_identity>
      <Hsp_positive>273</Hsp_positive>
      <Hsp_gaps>158</Hsp_gaps>
      <Hsp_align-len>630</Hsp_align-len>
      <Hsp_qseq>TNRIKTSKYNVVTFLPVNLFEQFQRVANAYFL------------------------FLLILQFRHRSDNQVNNRQSQVHINGKLQNEKWMN-------VRVGDIIKMENNQFVAADXXXXXXXEPHSLCYIETAELDG--------------------------------------FTGTLYWRGNTYS-LDNDKMLLRGCVLRNTEWCYGLVVFAGPDTKLMQNSGRTKLKRTSIDRLMNTL--VLWSAIGYYFQPYLPWESAVDSAIFSGF------LTFWSYIIILNTVVPISLYVSL--------VSMTQRRNIP-----PRSVPVDFSR--NLLADRRFFFYDQTM-LEAIRLG-----------------------------------------EWGVHEFFRLLALCHTVMPEEKTEGELAYQAQSPDEGALVTAARNFDFVFRSRTPETITL-HE-LGEPRTYQLLAILDFNNFRKRMSVIVRNAE-GRLKLYCKGADSVIFERLHPCNQQLVNITADHLSAFAGEGLRTLCLAYRDLDEASFEEWQERHHEANTSLQGREELLAAVYDE-IEQNMMLLGATAIEDKLQEETAVNIGYSCNMLTDDMNEVFVVSGHTVQEVR</Hsp_qseq>
      <Hsp_hseq>SNELSNAKYNAVTFVPTLLYEQFKFFYNLYFLVVALSQAVPALRIGYLSSYIVPLAFVLTVTMAKEAIDDIQRRRRDRESNNELYHVITRNRSIPSKDLKVGDLIKVHKGDRIPADLVLLQSSEPSGESFIKTDQLDGETDWKLRVACPLTQNLSENDLINRISITASAPEKSIHKFLGKVTYKDSTSNPLSVDNTLWANTVLASSGFCIACVVYTGRDTRQAMNTTTAKVKTGLLELEINSISKILCACV---------FALSILLVAFAGFHNDDWYIDILRYLILFSTIIPVSLRVNLDLAKSVYAHQIEHDKTIPETIVRTSTIPEDLGRIEYLLSDKTGTLTQNDMQLKKIHLGTVSYTSETLDIVSDYVQSLVSSKNDSLNNSKVALSTTRKDMSFRVRDMILTLAICHNVTPTFE-DDELTYQAASPDEIAIVKFTESVGLSLFKRDRHSISLLHEHSGKTLNYEILQVFPFNSDSKRMGIIVRDEQLDEYWFMQKGADTVM-SKIVESNDWLEEETGN----MAREGLRTLVIGRKKLNKKIYEQFQKEYNDASLSMLNRDQQMSQVITKYLEHDLELLGLTGVEDKLQKD----VKSSIELLRNAGIKIWMLTGDKVETAR</Hsp_hseq>
      <Hsp_midline>+N +  +KYN VTF+P  L+EQF+   N YFL                        F+L +     + + +  R+     N +L +    N       ++VGD+IK+     + ADL+LL SSEP    +I+T +LDG                                      F G + ++ +T + L  D  L    VL ++ +C   VV+ G DT+   N+   K+K   ++  +N++  +L + +         +  ++    F+GF      +    Y+I+ +T++P+SL V+L          +   + IP       ++P D  R   LL+D+        M L+ I LG                                          + V +    LA+CH V P  + + EL YQA SPDE A+V    +       R   +I+L HE  G+   Y++L +  FN+  KRM +IVR+ +        KGAD+V+  ++   N  L   T +     A EGLRTL +  + L++  +E++Q+ +++A+ S+  R++ ++ V  + +E ++ LLG T +EDKLQ++    +  S  +L +   ++++++G  V+  R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YMR162C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:578951:583921:-1 gene:YMR162C transcript:YMR162C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DNF3 description:Trans-golgi network aminophospholipid translocase (flippase); type 4 P-type ATPase; involved in phospholipid translocation, contributing to the maintenance of membrane lipid asymmetry in post-Golgi secretory vesicles; role in protein trafficking between the Golgi and endosomal system; localizes to the trans-Golgi network; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone [Source:SGD;Acc:S000004772]</Hit_def>
  <Hit_accession>YMR162C</Hit_accession>
  <Hit_len>1656</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>134.42</Hsp_bit-score>
      <Hsp_score>337</Hsp_score>
      <Hsp_evalue>5.32242e-32</Hsp_evalue>
      <Hsp_query-from>1096</Hsp_query-from>
      <Hsp_query-to>1917</Hsp_query-to>
      <Hsp_hit-from>1006</Hsp_hit-from>
      <Hsp_hit-to>1365</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>110</Hsp_identity>
      <Hsp_positive>165</Hsp_positive>
      <Hsp_gaps>102</Hsp_gaps>
      <Hsp_align-len>368</Hsp_align-len>
      <Hsp_qseq>GADSVIFERLHPCNQQLVNITADHLSAFAGEGLRTLCLAYRDLDEASFEEWQERHHEANTSLQGREELLAAVYDEIEQNMMLLGATAIEDKLQE------------------------ETAVNIGYSCNMLTD----------------DMNEV-------------FVVSGHTV---------QEVREELGRAKAKMLGLSKGSAANGFLYSSVKDPSKACPSIETTVEGDG------------------QEGMQAVLSSDYSFAXXXXXXXXXXVHGRWSYLRMCKFLCYFFYKNFAFTLT--------------VYDQWFITLFNIVYTSLPVLAMGVFDQDINDQWSIDCPKLYEPGQLNLLFN</Hsp_qseq>
      <Hsp_hseq>GSDELILNE-----EYVIERTLQAIDEFSTEGLRTLVYAYKWIDIGQYENWNKRYHQAKTSLTDRKIKVDEAGAEIEDGLNLLGVTAIEDKLQDGVSEAIEKIRRAGIKMWMLTGDKRETAINIGYSCMLIKDYSTVVILTTTDENIISKMNAVSQEVDSGNIAHCVVVIDGATMAMFEGNPTYMSVFVELCTKTDSVICCRASPSQKALMVSNIRNTD---PNLVTLAIGDGANDIAMIQSADIGVGIAGKEGLQASRVSDYSIGQFRFLLKLLFVHGRYNYIRTSKFMLCTFYKEITFYFTQLIYQRYTMFSGSSLYEPWSLSMFNTLFTSLPVLCIGMFEKDLKPMTLLTVPELYSYGRLSQGFN</Hsp_hseq>
      <Hsp_midline>G+D +I        + ++  T   +  F+ EGLRTL  AY+ +D   +E W +R+H+A TSL  R+  +     EIE  + LLG TAIEDKLQ+                        ETA+NIGYSC ++ D                 MN V              V+ G T+           V  EL      ++      +    + S++++     P++ T   GDG                  +EG+QA   SDYS  QFRFL +LL VHGR++Y+R  KF+   FYK   F  T              +Y+ W +++FN ++TSLPVL +G+F++D+     +  P+LY  G+L+  FN</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>94.3597</Hsp_bit-score>
      <Hsp_score>233</Hsp_score>
      <Hsp_evalue>1.0413e-19</Hsp_evalue>
      <Hsp_query-from>814</Hsp_query-from>
      <Hsp_query-to>1320</Hsp_query-to>
      <Hsp_hit-from>731</Hsp_hit-from>
      <Hsp_hit-to>890</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>183</Hsp_align-len>
      <Hsp_qseq>FFRLLALCHTVMP-----EEKTEGELAYQAQSPDEGALVTAARNFDFVFRSRTPETITLHEL-----GEPR--TYQLLAILDFNNFRKRMSVIVR--NAEGRLKLYCKGADSVIFERLHPCNQQLVNITADHLSAFAGEGLRTLCLAYRDLDEASFEEWQERHHEANTSLQGREELLAAVYDE</Hsp_qseq>
      <Hsp_hseq>FFLSLALCHSCLPKKTHNESIGEDSIEYQSSSPDELALVTAARDLGYIVLNRNAQILTIKTFPDGFDGEAKLENYEILNYIDFNSQRKRMSVLVRMPNQPNQVLLICKGADNVIMERLHD-------------RELAAKKMADICTSTKERKDA----------EAELVLQQRKSLERMVDEE</Hsp_hseq>
      <Hsp_midline>FF  LALCH+ +P     E   E  + YQ+ SPDE ALVTAAR+  ++  +R  + +T+        GE +   Y++L  +DFN+ RKRMSV+VR  N   ++ L CKGAD+VI ERLH                 A + +  +C + ++  +A          EA   LQ R+ L   V +E</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>2.77314e-12</Hsp_evalue>
      <Hsp_query-from>157</Hsp_query-from>
      <Hsp_query-to>669</Hsp_query-to>
      <Hsp_hit-from>291</Hsp_hit-from>
      <Hsp_hit-to>520</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>73</Hsp_gaps>
      <Hsp_align-len>237</Hsp_align-len>
      <Hsp_qseq>QVHINGKLQNEKWMNVRVGDIIKMENNQFVAADXXXXXXXEPHSLCYIETAELDG-----------------------------------------FTGTLYWRGN------TYSLDNDKMLLRGCVLRNTEWCYGLVVFAGPDTKLMQNSGRT-KLKRTSIDRLMN-----------TLVLWSAIGYYF--QPYLPWESA-----VDSAIFSGFLTFWSYIIILNTVVPISLYVSL</Hsp_qseq>
      <Hsp_hseq>NVHIHQK----KWEKLRVGDFVLLTQDDWVPADLLLLTCDGENSECFVETMALDGETNLKSKQPHPELNKLTKAASGLANINAQVTVEDPNIDLYNFEGNLELKNHRNDTIMKYPLGPDNVIYRGSILRNTQNVVGMVIFSGEETKIRMNALKNPRTKAPKLQRKINMIIVFMVFVVATISLFSYLGHVLHKKKYIDQNKAWYLFQADAGVAP---TIMSFIIMYNTVIPLSLYVTM</Hsp_hseq>
      <Hsp_midline> VHI+ K    KW  +RVGD + +  + +V ADLLLL+    +S C++ET  LDG                                         F G L  + +       Y L  D ++ RG +LRNT+   G+V+F+G +TK+  N+ +  + K   + R +N           T+ L+S +G+    + Y+    A      D+ +     T  S+II+ NTV+P+SLYV++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>102</Statistics_hsp-len>
      <Statistics_eff-space>2973630509</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052661-RA transcript Note:&quot;Similar to ESM1 Endothelial cell-specific molecule 1 (Homo sapiens)&quot; offset:0 AED:0.01 eAED:0.01 QI:0|1|0.66|1|0|0.33|3|2414|189</Iteration_query-def>
  <Iteration_query-len>2984</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>2023296965</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052662-RA transcript Note:&quot;Similar to snx33 Sorting nexin-33 (Xenopus laevis)&quot; offset:0 AED:0.23 eAED:0.23 QI:0|0.5|0.33|1|0.5|0.33|3|1057|524</Iteration_query-def>
  <Iteration_query-len>2632</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YOR069W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:453768:455795:1 gene:YOR069W transcript:YOR069W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VPS5 description:Nexin-1 homolog; required for localizing membrane proteins from a prevacuolar/late endosomal compartment back to late Golgi; structural component of retromer membrane coat complex; forms a retromer subcomplex with Vps17p; required for recruiting the retromer complex to the endosome membranes; VPS5 has a paralog, YKR078W, that arose from the whole genome duplication [Source:SGD;Acc:S000005595]</Hit_def>
  <Hit_accession>YOR069W</Hit_accession>
  <Hit_len>675</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>6.54292e-10</Hsp_evalue>
      <Hsp_query-from>535</Hsp_query-from>
      <Hsp_query-to>1305</Hsp_query-to>
      <Hsp_hit-from>281</Hsp_hit-from>
      <Hsp_hit-to>529</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>275</Hsp_align-len>
      <Hsp_qseq>FTCSIEDPTKQTKFKGMK---SFISYRLTPTFTGRAVSRRYKHFDWLYGRLVQKFPVVSVPHLPEKQATGRFVEDFVQKRRRGLILWMNHMTGHPVLAQCDAFQHFLTCTDEKAWKQGKRRAEKDDAVGAKFYLTISAPPTSHLDLQDVEARTDSFRSFSKRMDESVVLLNGTAGEMARKHCIDYKRDFQKMGQVFENLGQSFEQDD---------QHYSDNLTK------AITHTGNTYVAIGELFAXXXXXXXXXXXXVTCLYQGLLANFPDI</Hsp_qseq>
      <Hsp_hseq>FKVEVKDPVKVGELTSIHVEYTVISESSLLELKYAQVSRRYRDFRWLYRQLQNNHWGKVIPPPPEKQSVGSFKENFIENRRFQMESMLKKICQDPVLQKDKDFLLFLTSDDFSS--ESKKRA----------FLTGSGAINDSNDLSEV------------RISEIQLLGAEDAAEVLKNGGIDAESHKGFMSISFSSLPKYNEADEFFIEKKQKIDELEDNLKKLSKSLEMVDTSRNTLAASTEEFS--SMVETLASLNVSEPNSELLNNFADV</Hsp_hseq>
      <Hsp_midline>F   ++DP K  +   +    + IS           VSRRY+ F WLY +L        +P  PEKQ+ G F E+F++ RR  +   +  +   PVL +   F  FLT  D  +  + K+RA          +LT S       DL +V            R+ E  +L    A E+ +   ID +     M   F +L +  E D+             DNL K       +  + NT  A  E F+     +    ++V+     LL NF D+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YMR004W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:274017:275552:1 gene:YMR004W transcript:YMR004W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MVP1 description:Protein required for sorting proteins to the vacuole; Mvp1p and Vps1p act in concert to promote membrane traffic to the vacuole; participates in transcription initiation and/or early elongation of specific genes; interacts with &quot;foot domain&quot; of RNA polymerase II; deletion results in abnormal CTD-Ser5 phosphorylation of RNA polymerase II at specific promoter regions; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004606]</Hit_def>
  <Hit_accession>YMR004W</Hit_accession>
  <Hit_len>511</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>3.29809e-09</Hsp_evalue>
      <Hsp_query-from>583</Hsp_query-from>
      <Hsp_query-to>876</Hsp_query-to>
      <Hsp_hit-from>152</Hsp_hit-from>
      <Hsp_hit-to>251</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>53</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>100</Hsp_align-len>
      <Hsp_qseq>MKSFISYRLTPTFTGRAVSRRYKHFDWLYGRLVQKFPVVSVPHLPEKQATGRFVED-FVQKRRRGLILWMNHMTGHPVLAQCDAFQHFLTC-TDEKAWKQ</Hsp_qseq>
      <Hsp_hseq>VKHLIALPSTSPSEERTVVRRYSDFLWLREILLKRYPFRMIPELPPKRIGSQNADQLFLKKRRIGLSRFINLVMKHPKLSNDDLVLTFLTVRTDLTSWRK</Hsp_hseq>
      <Hsp_midline>+K  I+   T     R V RRY  F WL   L++++P   +P LP K+   +  +  F++KRR GL  ++N +  HP L+  D    FLT  TD  +W++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YOR357C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:1009224:1009712:-1 gene:YOR357C transcript:YOR357C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNX3 description:Sorting nexin for late-Golgi enzymes; required to maintain late-Golgi resident enzymes in their proper location by recycling molecules from the prevacuolar compartment; contains a PX domain and sequence similarity to human Snx3p [Source:SGD;Acc:S000005884]</Hit_def>
  <Hit_accession>YOR357C</Hit_accession>
  <Hit_len>162</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>1.87335e-08</Hsp_evalue>
      <Hsp_query-from>613</Hsp_query-from>
      <Hsp_query-to>816</Hsp_query-to>
      <Hsp_hit-from>69</Hsp_hit-from>
      <Hsp_hit-to>144</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>43</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>76</Hsp_align-len>
      <Hsp_qseq>PTFTGRA--VSRRYKHFDWLYGRLVQKF-----PVVSVPHLPEK-QATGRFVEDFVQKRRRGLILWMNHMTGHPVL</Hsp_qseq>
      <Hsp_hseq>PSFHKRVSKVRRRYSDFEFFRKCLIKEISMLNHPKVMVPHLPGKILLSNRFSNEVIEERRQGLNTWMQSVAGHPLL</Hsp_hseq>
      <Hsp_midline>P+F  R   V RRY  F++    L+++      P V VPHLP K   + RF  + +++RR+GL  WM  + GHP+L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YJL036W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:378825:380096:1 gene:YJL036W transcript:YJL036W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNX4 description:Sorting nexin; involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Golgi network and in cytoplasm to vacuole transport; contains a PX phosphoinositide-binding domain; forms complexes with Snx41p and with Atg20p [Source:SGD;Acc:S000003573]</Hit_def>
  <Hit_accession>YJL036W</Hit_accession>
  <Hit_len>423</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>2.75781e-08</Hsp_evalue>
      <Hsp_query-from>490</Hsp_query-from>
      <Hsp_query-to>1128</Hsp_query-to>
      <Hsp_hit-from>15</Hsp_hit-from>
      <Hsp_hit-to>238</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>235</Hsp_align-len>
      <Hsp_qseq>DIADRGPAWPDNPFPFTCSIEDPTKQTKFKGMKS-FISYRL------TPTFTGR-------AVSRRYKHFDWLYGRLVQKFPVVSVPHLPEKQ-----ATGRFVEDFVQKRRRGLILWMNHMTGHPVLAQCDAFQHFLTCTDEKAWK---QGKRRAEKDDAVGAKFYLTISAPPTSHLDLQDVEARTDSFRSFSKRMDESVVLLNGTAGEMARKHCIDYKRDFQKMGQVFENLGQ</Hsp_qseq>
      <Hsp_hseq>DKARGNPEKP--PYWFEIIVSDPQKRTGDPGSSSGYVSYQISTKTNNTSFYDNRGDPESIIVVHRRYSDLLLLHDILLNRFPTCIIPPLPDKKVFQYIAGDRFSQRFTQKRCHSLQNFLRRVSLHPDLSQSKVFKTFLVSKDWESHRKVLQDSLQPNKDEVTDA----FMNAFKTVH---KQNEEFTE-IREKSDKLDRTVTKIDKLFHKVVKKND-SMSEDYTKLGSNLQELQE</Hsp_hseq>
      <Hsp_midline>D A   P  P  P+ F   + DP K+T   G  S ++SY++      T  +  R        V RRY     L+  L+ +FP   +P LP+K+     A  RF + F QKR   L  ++  ++ HP L+Q   F+ FL   D ++ +   Q   +  KD+   A     ++A  T H   +  E  T+  R  S ++D +V  ++    ++ +K+      D+ K+G   + L +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YHL002W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:102612:103970:1 gene:YHL002W transcript:YHL002W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSE1 description:Subunit of the endosomal Vps27p-Hse1p complex; complex is required for sorting of ubiquitinated membrane proteins into intralumenal vesicles prior to vacuolar degradation, as well as for recycling of Golgi proteins and formation of lumenal membranes [Source:SGD;Acc:S000000994]</Hit_def>
  <Hit_accession>YHL002W</Hit_accession>
  <Hit_len>452</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>4.7741e-06</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>171</Hsp_query-to>
      <Hsp_hit-from>218</Hsp_hit-from>
      <Hsp_hit-to>271</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>26</Hsp_identity>
      <Hsp_positive>33</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>56</Hsp_align-len>
      <Hsp_qseq>VSRRARALYDFQSENEGEISIRERDVLTVFNEGVGDGWFEGTNSRGERGLFPATYV</Hsp_qseq>
      <Hsp_hseq>VVRRVRALYDLTTNEPDELSFRKGDVITVL-EQVYRDWWKGA-LRGNMGIFPLNYV</Hsp_hseq>
      <Hsp_midline>V RR RALYD  +    E+S R+ DV+TV  E V   W++G   RG  G+FP  YV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YDR162C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:780390:781100:-1 gene:YDR162C transcript:YDR162C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NBP2 description:Protein involved in the HOG (high osmolarity glycerol) pathway; negatively regulates Hog1p by recruitment of phosphatase Ptc1p the Pbs2p-Hog1p complex; interacts with Bck1p and down regulates the cell wall integrity pathway; found in the nucleus and cytoplasm, contains an SH3 domain and a Ptc1p binding domain (PBM) [Source:SGD;Acc:S000002569]</Hit_def>
  <Hit_accession>YDR162C</Hit_accession>
  <Hit_len>236</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.2098</Hsp_bit-score>
      <Hsp_score>108</Hsp_score>
      <Hsp_evalue>8.02195e-06</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>192</Hsp_query-to>
      <Hsp_hit-from>110</Hsp_hit-from>
      <Hsp_hit-to>173</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>39</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>65</Hsp_align-len>
      <Hsp_qseq>MVSRRARALYDFQSENEGEISIRERDVLTVFNEGVGDGWFEGTNSRGER-GLFPATYVEFLPDED</Hsp_qseq>
      <Hsp_hseq>IVNQRAVALYDFEPENDNELRLAEGDIVFISYKH-GQGWLVAENESGSKTGLVPEEFVSYIQPED</Hsp_hseq>
      <Hsp_midline>+V++RA ALYDF+ EN+ E+ + E D++ +  +  G GW    N  G + GL P  +V ++  ED</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1766200993</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052664-RA transcript Note:&quot;Similar to Clk2 Dual specificity protein kinase CLK2 (Mus musculus)&quot; offset:272 AED:0.33 eAED:0.33 QI:272|0.90|0.91|1|0.09|0.16|12|1988|486</Iteration_query-def>
  <Iteration_query-len>3721</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YLL019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:105686:107899:-1 gene:YLL019C transcript:YLL019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KNS1 description:Protein kinase involved in negative regulation of PolIII transcription; effector kinase of the TOR signaling pathway and phosphorylates Rpc53p to regulate ribosome and tRNA biosynthesis; member of the LAMMER family of protein kinases, which are serine/threonine kinases also capable of phosphorylating tyrosine residues; capable of autophosphorylation [Source:SGD;Acc:S000003942]</Hit_def>
  <Hit_accession>YLL019C</Hit_accession>
  <Hit_len>737</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>199.134</Hsp_bit-score>
      <Hsp_score>505</Hsp_score>
      <Hsp_evalue>1.91289e-53</Hsp_evalue>
      <Hsp_query-from>822</Hsp_query-from>
      <Hsp_query-to>1424</Hsp_query-to>
      <Hsp_hit-from>348</Hsp_hit-from>
      <Hsp_hit-to>561</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>90</Hsp_identity>
      <Hsp_positive>136</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>214</Hsp_align-len>
      <Hsp_qseq>VDKYREAARLEINVLEKINEKDPRNKYLCVQMYDWFDYHGHMCIAFELLGLSTFDFLKENNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQK-------------KRDERTVRNADIRVVDFGSATFDYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLG</Hsp_qseq>
      <Hsp_hseq>VDRYREAAKTELRILQTILNNDPQGQFQCLLLRECFDYKNHICLVTDLYGRSIYDFMCSNGIARFPGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENILICDETHIAQKLPLKTVQSLSKRRREASKGKRKILKNPEIKIIDFGSAIFHYEYHPPVISTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVIGESLYPIHENLEHMAMMQRING</Hsp_hseq>
      <Hsp_midline>VD+YREAA+ E+ +L+ I   DP+ ++ C+ + + FDY  H+C+  +L G S +DF+  N    +P   ++ +A QL  ++ FLHD  + HTDLKPENIL  D  +  +  P K             K   + ++N +I+++DFGSA F YE+H  ++STRHYRAPE++L LGWS PCD+WSI C++ E  +G +L+  H+N EH+AMM+R  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>132.109</Hsp_bit-score>
      <Hsp_score>331</Hsp_score>
      <Hsp_evalue>1.04851e-31</Hsp_evalue>
      <Hsp_query-from>828</Hsp_query-from>
      <Hsp_query-to>1667</Hsp_query-to>
      <Hsp_hit-from>405</Hsp_hit-from>
      <Hsp_hit-to>704</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>94</Hsp_identity>
      <Hsp_positive>147</Hsp_positive>
      <Hsp_gaps>56</Hsp_gaps>
      <Hsp_align-len>318</Hsp_align-len>
      <Hsp_qseq>KYREAARLEINVLEKINEK-DPRNKYLCVQMYDWFDYHGHMCIAFELLGLSTFDFLKENNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAG-----KYVRENC-------KP-------------LRRYVVCDDAQHHQ------------LFDLIEKMLQYEPSKRITLGEALKHPFF</Hsp_qseq>
      <Hsp_hseq>EYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKNHLCLVFELLSNNLYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCA--------PDK---------PELKIIDFGSSCEEARTVYTYIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAELFLGIPIFPGASEYNQLTRIIDTLGYPPSWMIDMGKNSGKFMK-KLAPEESSSSTQKHRMKTIEEFCREYNIVEKPSKQYFKWRKLPDIIRNYRYPKSIQNSQELIDQEMQNRECLIHFLGGVLNLNPLERWTPQQAMLHPFI</Hsp_hseq>
      <Hsp_midline>+Y   +  E  +LE +N+K DP NK+  ++MYD F +  H+C+ FELL  + ++ LK+N +    +  +R    Q+  ++  L ++KL H DLKPENIL           P K          +++++DFGS+  +     T + +R YRAPE++L + +S   D+WS+GCIV E +LG  +F        L  +  TLG  PS M+   +    F    L  +ESSS+      K + E C       KP             +R Y      Q+ Q            L   +  +L   P +R T  +A+ HPF </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>96.2857</Hsp_bit-score>
      <Hsp_score>238</Hsp_score>
      <Hsp_evalue>4.08463e-21</Hsp_evalue>
      <Hsp_query-from>1041</Hsp_query-from>
      <Hsp_query-to>1673</Hsp_query-to>
      <Hsp_hit-from>134</Hsp_hit-from>
      <Hsp_hit-to>320</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>52</Hsp_gaps>
      <Hsp_align-len>225</Hsp_align-len>
      <Hsp_qseq>AYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNAD--IRVVDFGSATFDYEHH-------STIVSTRHYRAPEVLLEL-GWSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRK---QKYFHH-GHLDWDESSSAGKYVRENCKPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPFFDL</Hsp_qseq>
      <Hsp_hseq>TYQILCGLKYIHSADVLHRDLKPGNLLV---------------------NADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFI-----------------PKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPYLSI</Hsp_hseq>
      <Hsp_midline> YQ+   +K++H   + H DLKP N+L                      NAD  +++ DFG A    E+        +  V+TR YRAPE++L   G+++  DVWS GCI+ EF  G  +F+  D    L  + + LG  P   +RR      Q Y H  G +                 P   +V      + Q  DL+E+ML ++P KRIT+ EAL+HP+  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>91.2781</Hsp_bit-score>
      <Hsp_score>225</Hsp_score>
      <Hsp_evalue>5.54233e-20</Hsp_evalue>
      <Hsp_query-from>1029</Hsp_query-from>
      <Hsp_query-to>1667</Hsp_query-to>
      <Hsp_hit-from>114</Hsp_hit-from>
      <Hsp_hit-to>309</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>219</Hsp_align-len>
      <Hsp_qseq>VRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHHSTIVSTRHYRAPEVLLELG-WSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENCKPLRRYVVCDDAQ-----HHQLFDLIEKMLQYEPSKRITLGEALKHPFF</Hsp_qseq>
      <Hsp_hseq>IQYFIYQTLRAVKVLHGSNVIHRDLKPSNLL-INSNCDLKVC-----DFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGT-----------------PHSDNDLRCIESPRAREYIKSLPMYPAAPLEKMFPRVNPKGIDLLQRMLVFDPAKRITAKEALEHPYL</Hsp_hseq>
      <Hsp_midline>++   YQ   A+K LH + + H DLKP N+L ++S  D+K       D    R  D    D    T      +  V+TR YRAPEV+L    +S+  DVWS GCI+ E +L   +F   D R  L ++   +G                   H D D         RE  K L  Y      +     + +  DL+++ML ++P+KRIT  EAL+HP+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>89.7373</Hsp_bit-score>
      <Hsp_score>221</Hsp_score>
      <Hsp_evalue>4.72466e-19</Hsp_evalue>
      <Hsp_query-from>1029</Hsp_query-from>
      <Hsp_query-to>1664</Hsp_query-to>
      <Hsp_hit-from>121</Hsp_hit-from>
      <Hsp_hit-to>301</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>219</Hsp_align-len>
      <Hsp_qseq>VRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHHSTIVSTRHYRAPEVLLELGWSQ---PCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHH----GHLDWDESSSAGKYVRENCKPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPF</Hsp_qseq>
      <Hsp_hseq>VQYFLYQILRGLKYVHSAGVIHRDLKPSNILINE-------------------NCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLT--WQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENTLKFVTSLPHRDPIPFSERFKTVEPDA-----------------VDLLEKMLVFDPKKRITAADALAHPY</Hsp_hseq>
      <Hsp_midline>V+   YQ+   +K++H   + H DLKP NIL  +                   N D+++ DFG A       +  VSTR+YRAPE++L   W +     D+WS GCI  E   G  LF   D+    +++   LG  P  ++     +          H D    S   K V  +                   DL+EKML ++P KRIT  +AL HP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.6557</Hsp_bit-score>
      <Hsp_score>213</Hsp_score>
      <Hsp_evalue>2.15638e-18</Hsp_evalue>
      <Hsp_query-from>1029</Hsp_query-from>
      <Hsp_query-to>1673</Hsp_query-to>
      <Hsp_hit-from>120</Hsp_hit-from>
      <Hsp_hit-to>315</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>57</Hsp_gaps>
      <Hsp_align-len>234</Hsp_align-len>
      <Hsp_qseq>VRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSA---TFDYEHHSTI-------VSTRHYRAPEVLLELG-WSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPS----RMVRRTRKQKYFHH----GHLDWDESSSAGKYVRENCKPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPFFDL</Hsp_qseq>
      <Hsp_hseq>VQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNS-------------------NCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLG-TPSFEDFNQIKSKRAKEYIANLPMRPPLPWETVWS-----KTDLNP-------------DMIDLLDKMLQFNPDKRISAAEALRHPYLAM</Hsp_hseq>
      <Hsp_midline>V+   YQ+  A+K +H  ++ H D+KP N+L                      N D++V DFG A       +   T+       V+TR YRAPE++L    ++   D+WS GCI+ E   G  LF   D    L ++   LG  PS      ++  R ++Y  +      L W+   S     + +  P              + DL++KMLQ+ P KRI+  EAL+HP+  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.0333</Hsp_bit-score>
      <Hsp_score>201</Hsp_score>
      <Hsp_evalue>7.56476e-17</Hsp_evalue>
      <Hsp_query-from>999</Hsp_query-from>
      <Hsp_query-to>1685</Hsp_query-to>
      <Hsp_hit-from>131</Hsp_hit-from>
      <Hsp_hit-to>333</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>239</Hsp_align-len>
      <Hsp_qseq>NNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHHSTIVS---TRHYRAPEVLLE-LGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENCKPL------RRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPFFDLLAQD</Hsp_qseq>
      <Hsp_hseq>TNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVL-VDPETGV-----------------LKICDFGSAK-KLEHNQPSISYICSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLREIAKLLGPPDKRFI-------FFSNPAYDGPLFS----------KPLFSGSSQQRFEKYFGHSGPDGIDLLMKILVYEPQQRLSPRRILAHQFFNELRND</Hsp_hseq>
      <Hsp_midline> N L  PL  +RL  YQ+   + +LH   + H D+KP N+L VD E  +                 +++ DFGSA    EH+   +S   +R YRAPE+++    ++   D+W +GC++ E  +G  +FQ  +    L  + + LG    R +       +F +   D    S          KPL      +R+            DL+ K+L YEP +R++    L H FF+ L  D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.0333</Hsp_bit-score>
      <Hsp_score>201</Hsp_score>
      <Hsp_evalue>1.27639e-16</Hsp_evalue>
      <Hsp_query-from>1044</Hsp_query-from>
      <Hsp_query-to>1673</Hsp_query-to>
      <Hsp_hit-from>135</Hsp_hit-from>
      <Hsp_hit-to>320</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>222</Hsp_align-len>
      <Hsp_qseq>YQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHHST-------IVSTRHYRAPEVLLELG-WSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKY----FHHGHLDWDESSSAGKYVRENCKPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPFFDL</Hsp_qseq>
      <Hsp_hseq>YQILCALKYIHSANVLHCDLKPKNLL-VNSD------------------CQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNI-----------------PGRSFESILPGANPEALELLKKMLEFDPKKRITVEDALEHPYLSM</Hsp_hseq>
      <Hsp_midline>YQ+  A+K++H   + H DLKP+N+L V+S+                    +++ +FG +    E+H          +++  Y+APE+LL     ++  D+WS GCI+ E      +F+  D  +HL  + + LG  P   ++    QK     F  G++                 P R +       + +  +L++KML+++P KRIT+ +AL+HP+  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.6481</Hsp_bit-score>
      <Hsp_score>200</Hsp_score>
      <Hsp_evalue>1.65526e-16</Hsp_evalue>
      <Hsp_query-from>906</Hsp_query-from>
      <Hsp_query-to>1667</Hsp_query-to>
      <Hsp_hit-from>98</Hsp_hit-from>
      <Hsp_hit-to>299</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>62</Hsp_gaps>
      <Hsp_align-len>259</Hsp_align-len>
      <Hsp_qseq>CVQMYDWFDYHGHMCIAFELL-GLSTFD-FLKENNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSAT---FDYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENCKPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPFF</Hsp_qseq>
      <Hsp_hseq>IVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEE--DAVRILV-EILSAVKYMHSQNIVHRDLKPENLLYID-----------KSDE-----SPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQDFLD--ECTTGEYPVK----------FHRPY--WDSVSNKAK------------------------QFILKALNLDPSKRPTAAELLEDPWI</Hsp_hseq>
      <Hsp_midline> V   DWF+      I  +L  G   FD  LK+  +       VR++  ++  A+K++H   + H DLKPEN+L++D           K DE     + + V DFG A     D E       +  Y APEVL + G  +PCD+WSIG I +    G++ F+    ++ L   E T G  P +          FH  +  WD  S+  K                          I K L  +PSKR T  E L+ P+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YMR216C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:698811:701039:-1 gene:YMR216C transcript:YMR216C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKY1 description:SR protein kinase (SRPK); involved in regulating proteins involved in mRNA metabolism and cation homeostasis; similar to human SRPK1 [Source:SGD;Acc:S000004829]</Hit_def>
  <Hit_accession>YMR216C</Hit_accession>
  <Hit_len>742</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.4185</Hsp_bit-score>
      <Hsp_score>202</Hsp_score>
      <Hsp_evalue>2.42576e-16</Hsp_evalue>
      <Hsp_query-from>1197</Hsp_query-from>
      <Hsp_query-to>1688</Hsp_query-to>
      <Hsp_hit-from>546</Hsp_hit-from>
      <Hsp_hit-to>714</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>IRVVDFGSATFDYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLFQ-------THDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENCKPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPFF-DLLAQDQ</Hsp_qseq>
      <Hsp_hseq>IKIADLGNACWYDEHYTNSIQTREYRSPEVLLGAPWGCGADIWSTACLIFELITGDFLFEPDEGHSYTKDD-DHIAQIIELLGELPSYLLRNGKYTRTFFNSRGLLRNISKLKFWPLEDVLTEKYKFSKDEAK--EISDFLSPMLQLDPRKRADAGGLVNHPWLKDTLGMEE</Hsp_hseq>
      <Hsp_midline>I++ D G+A +  EH++  + TR YR+PEVLL   W    D+WS  C++FE   G  LF+       T D+ +H+A +   LG +PS ++R  +  + F +        S    +  E+    +     D+A+  ++ D +  MLQ +P KR   G  + HP+  D L  ++</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>4.8492e-08</Hsp_evalue>
      <Hsp_query-from>831</Hsp_query-from>
      <Hsp_query-to>1124</Hsp_query-to>
      <Hsp_hit-from>195</Hsp_hit-from>
      <Hsp_hit-to>302</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>108</Hsp_align-len>
      <Hsp_qseq>YREAARLEINVLEKINE-----KDPRNKYLCVQMYDWFDYHG----HMCIAFELLGLSTFDFLKENNYLPYPLHQVRLMAYQLCYAIKFLHDN-KLTHTDLKPENILF</Hsp_qseq>
      <Hsp_hseq>YTEAAEDEIKLLQRVNDADNTKEDSMGANHILKLLDHFNHKGPNGVHVVMVFEVLGENLLALIKKYEHRGIPLIYVKQISKQLLLGLDYMHRRCGIIHTDIKPENVLM</Hsp_hseq>
      <Hsp_midline>Y EAA  EI +L+++N+     +D       +++ D F++ G    H+ + FE+LG +    +K+  +   PL  V+ ++ QL   + ++H    + HTD+KPEN+L </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.4925</Hsp_bit-score>
      <Hsp_score>197</Hsp_score>
      <Hsp_evalue>2.96326e-16</Hsp_evalue>
      <Hsp_query-from>1029</Hsp_query-from>
      <Hsp_query-to>1727</Hsp_query-to>
      <Hsp_hit-from>143</Hsp_hit-from>
      <Hsp_hit-to>357</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>248</Hsp_align-len>
      <Hsp_qseq>VRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSA----TFDYEHHSTI-------VSTRHYRAPEVLLE-LGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENCKPLRRYVVCDDA---QHHQLFDLIEKMLQYEPSKRITLGEALKHPFFDLLAQDQRSAVRRDTPRDLS</Hsp_qseq>
      <Hsp_hseq>IKYFLYQILCGLKYIHSADVIHRDLKPGNIL-------------------CTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDKDILIKFGTIKAWNLG--------------KNSNNPVYKKIPWSNIFPFASHEAINLIESLLHWDSTHRLNVEQAISHPFLNEVRKPDDEPVCLQGPFDFT</Hsp_hseq>
      <Hsp_midline>++   YQ+   +K++H   + H DLKP NIL                      N  +++ DFG A       ++ HST+       V+TR YRAPE+LL    +S+  D+W++GCI+ EFY    +F   D+   +  + + LG     ++ +    K ++ G              + +  P+ + +   +      H+  +LIE +L ++ + R+ + +A+ HPF + + +     V    P D +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.2554</Hsp_bit-score>
      <Hsp_score>186</Hsp_score>
      <Hsp_evalue>3.01168e-15</Hsp_evalue>
      <Hsp_query-from>906</Hsp_query-from>
      <Hsp_query-to>1667</Hsp_query-to>
      <Hsp_hit-from>65</Hsp_hit-from>
      <Hsp_hit-to>297</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>114</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>267</Hsp_align-len>
      <Hsp_qseq>CVQMYDWFDYHGHMCIAFELLGLSTFDFLKENNYLPYP----LHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSA---TFDYEHHSTIVSTRHYRAPEVLL-ELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLG-----LIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENCKPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPFF</Hsp_qseq>
      <Hsp_hseq>IVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLI------------NKRGQ-------LKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPS----VTKLPKY------NPNIQQRPPRDLRQVLQPHTK-----EPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWF</Hsp_hseq>
      <Hsp_midline> V++YD       + + FE +      ++        P    L+ V+   +QL   + F H+NK+ H DLKP+N+L              KR +       +++ DFG A          S+ V T  YRAP+VL+    +S   D+WS GCI+ E   G  LF   ++ E L ++   +G     L PS     T+  KY      + +      + +R+  +P  +     +     L D +  +LQ  P  R++  +AL HP+F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.7962</Hsp_bit-score>
      <Hsp_score>190</Hsp_score>
      <Hsp_evalue>5.90828e-15</Hsp_evalue>
      <Hsp_query-from>888</Hsp_query-from>
      <Hsp_query-to>1697</Hsp_query-to>
      <Hsp_hit-from>122</Hsp_hit-from>
      <Hsp_hit-to>396</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>289</Hsp_align-len>
      <Hsp_qseq>PRNKYLCVQMYDWF----DYHGHMCIAFELLGLSTFDFLKENNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSE--YDIKYNPQKKRDERTVRNADIRVVDFGSA--TFDYEHHSTIVSTRHYRAPEVLLELG-WSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLD-------WDESSSAGKYVREN---CKPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPFFDLLAQDQRSA</Hsp_qseq>
      <Hsp_hseq>PANDHL-IQIFEVFIDSENYQLH--IVMECMEQNLYQMMKHRRRRVFSIPSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYV----IKLADFGLARHVENKNPYTAYVSTRWYRSPEILLRSGYYSKPLDIWAFGCVAVEVTVFRALFPGANEIDQIWKILEVLG-------TPIKRSDFVNTNHITAPPPGGFWDDASNLVHKLNLKLPYVEGSSLDHLLSSSQLSDLSEVVKKCLRWDPNERATAQELCEMPFFENTVASQVDA</Hsp_hseq>
      <Hsp_midline>P N +L +Q+++ F    +Y  H  I  E +  + +  +K      + +  ++ +  Q+   +K +H++   H DLKPENIL   S   ++ +Y  Q    +  V    I++ DFG A    +   ++  VSTR YR+PE+LL  G +S+P D+W+ GC+  E  +   LF   +  + +  +   LG          ++  + +  H+        WD++S+    +       +      +   +Q   L ++++K L+++P++R T  E  + PFF+     Q  A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.485</Hsp_bit-score>
      <Hsp_score>184</Hsp_score>
      <Hsp_evalue>1.93351e-14</Hsp_evalue>
      <Hsp_query-from>1047</Hsp_query-from>
      <Hsp_query-to>1682</Hsp_query-to>
      <Hsp_hit-from>311</Hsp_hit-from>
      <Hsp_hit-to>485</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>218</Hsp_align-len>
      <Hsp_qseq>QLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKR----DERTVRNADIRVVDFGSATFDYEHH--STIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENCKPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPFFDLLAQ</Hsp_qseq>
      <Hsp_hseq>QLLTGLKYLHEQNIIHRDIKPENILLNITR---RENPSQVQLGPWDEDEI-DIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVILYVCLCGFPPFSDQ--------------LGPPSLKEQILQAKYAFYSPY-WDK--------------------IDDSVLH----LISNLLVLNPDERYNIDEALNHPWFNDIQQ</Hsp_hseq>
      <Hsp_midline>QL   +K+LH+  + H D+KPENIL   +    + NP + +    DE  + +  +++ DFG A F  E    +T+  T  Y APEVL + G++   D+WS G I++    GF  F                 L P  +  +  + KY  +    WD+                     DD+  H    LI  +L   P +R  + EAL HP+F+ + Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YDL079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:312951:314748:-1 gene:YDL079C transcript:YDL079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRK1 description:Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication [Source:SGD;Acc:S000002237]</Hit_def>
  <Hit_accession>YDL079C</Hit_accession>
  <Hit_len>501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.3294</Hsp_bit-score>
      <Hsp_score>181</Hsp_score>
      <Hsp_evalue>5.4777e-14</Hsp_evalue>
      <Hsp_query-from>1017</Hsp_query-from>
      <Hsp_query-to>1670</Hsp_query-to>
      <Hsp_hit-from>261</Hsp_hit-from>
      <Hsp_hit-to>448</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>222</Hsp_align-len>
      <Hsp_qseq>PLHQVRLMAYQLCYAIKFLHD-NKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHHSTI--VSTRHYRAPEVLL-ELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENCKPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPFFD</Hsp_qseq>
      <Hsp_hseq>PRVEIKFYAYQLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFK------------------ICDFGSAKCLKPDQPNVSYICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKIMG-IPTKDEISGMNPNYEDH--------------VFPNIKPITLAEIF-KAEDPDTLDLLTKTLKYHPCERLVPLQCLLSSYFD</Hsp_hseq>
      <Hsp_midline>P  +++  AYQL  A+ +LH+  ++ H D+KP+N+L   + +  K                  + DFGSA         +  + +R+YRAPE++     +S   DVWS  C++ E  LG  LF      + L  + + +G IP++         Y  H              V  N KP+    +   A+     DL+ K L+Y P +R+   + L   +FD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>6.5286e-14</Hsp_evalue>
      <Hsp_query-from>1017</Hsp_query-from>
      <Hsp_query-to>1460</Hsp_query-to>
      <Hsp_hit-from>146</Hsp_hit-from>
      <Hsp_hit-to>278</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>151</Hsp_align-len>
      <Hsp_qseq>PLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATF--DYEHHSTIVSTRHYRAPEVLLELG-WSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRK</Hsp_qseq>
      <Hsp_hseq>PTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPS------------------SGIAKVCDFGSAQRLDDNTELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPLFKGDSANSQLEEIAKLLGRFPKSSIKNSQE</Hsp_hseq>
      <Hsp_midline>P   ++L  +Q+  A+  LH   + H DLKP NIL + S                  +   +V DFGSA    D     T   +R YRAPE+LL    ++   D+WS+GCI+ E   G  LF+       L  + + LG  P   ++ +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.559</Hsp_bit-score>
      <Hsp_score>179</Hsp_score>
      <Hsp_evalue>1.20833e-13</Hsp_evalue>
      <Hsp_query-from>906</Hsp_query-from>
      <Hsp_query-to>1385</Hsp_query-to>
      <Hsp_hit-from>141</Hsp_hit-from>
      <Hsp_hit-to>285</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>166</Hsp_align-len>
      <Hsp_qseq>CVQMYDWFDYHGHMCIAFELL-GLSTFDFLKENNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATF---DYEHHSTIVSTRHYRAPEVLL--ELGWSQPCDVWSIGCIVFEFYLGFTLFQTHD</Hsp_qseq>
      <Hsp_hseq>IVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEP--EVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFF-DSNYNLK------------------IGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARD</Hsp_hseq>
      <Hsp_midline> VQ  D F+   ++ I  E+    S  + LK    L  P  +VR    Q+C AIK++H  ++ H DLK  NI F DS Y++K                  + DFG A     + E   TI  T +Y APEVL+    G S   D+WS+G +++   +G   FQ  D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.7886</Hsp_bit-score>
      <Hsp_score>177</Hsp_score>
      <Hsp_evalue>1.22467e-13</Hsp_evalue>
      <Hsp_query-from>852</Hsp_query-from>
      <Hsp_query-to>1373</Hsp_query-to>
      <Hsp_hit-from>96</Hsp_hit-from>
      <Hsp_hit-to>249</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>179</Hsp_align-len>
      <Hsp_qseq>EINVLEKINEKDPRNKYLCVQMYDWFDYHGHMCIAFEL-LGLSTFD-FLKENNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHHSTI---VSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLF</Hsp_qseq>
      <Hsp_hseq>ELSILQKLSHPN------IVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEI---IVQILGAVEYMHSKNVVHRDLKPENVLYVDKS----------------ENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSPF</Hsp_hseq>
      <Hsp_midline>E+++L+K++  +       V   DWF+      I  +L  G   FD  L    +      ++     Q+  A++++H   + H DLKPEN+L+VD                   N+ + + DFG A         I     +  Y APEVL + G  +PCD+WSIG I +    G++ F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>5.36912e-13</Hsp_evalue>
      <Hsp_query-from>969</Hsp_query-from>
      <Hsp_query-to>1373</Hsp_query-to>
      <Hsp_hit-from>169</Hsp_hit-from>
      <Hsp_hit-to>282</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>135</Hsp_align-len>
      <Hsp_qseq>GLSTFDFLKENNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLF</Hsp_qseq>
      <Hsp_hseq>GGELFSLLRKSQRFPNPV--AKFYAAEVCLALEYLHSKDIIYRDLKPENILLD-------------------KNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPF</Hsp_hseq>
      <Hsp_midline>G   F  L+++   P P+   +  A ++C A+++LH   + + DLKPENIL                     +N  I++ DFG A +  +   T+  T  Y APEV+    +++  D WS G +++E   G+T F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>7.43096e-13</Hsp_evalue>
      <Hsp_query-from>903</Hsp_query-from>
      <Hsp_query-to>1373</Hsp_query-to>
      <Hsp_hit-from>147</Hsp_hit-from>
      <Hsp_hit-to>283</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>158</Hsp_align-len>
      <Hsp_qseq>LCVQMYDWFDYHGHMCIAFELL-GLSTFDFLKENNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLF</Hsp_qseq>
      <Hsp_hseq>FIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPV--AKFYAAEVCLALEYLHSKDIIYRDLKPENILLD-------------------KNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPF</Hsp_hseq>
      <Hsp_midline>  ++M+  F     + +  + + G   F  L+++   P P+   +  A ++C A+++LH   + + DLKPENIL                     +N  I++ DFG A +  +   T+  T  Y APEV+    +++  D WS G +++E   G+T F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>1.26191e-12</Hsp_evalue>
      <Hsp_query-from>1026</Hsp_query-from>
      <Hsp_query-to>1685</Hsp_query-to>
      <Hsp_hit-from>139</Hsp_hit-from>
      <Hsp_hit-to>328</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>QVRLMAYQLCYAIKFLHD-NKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSAT--FDYEHHSTIVSTRHYRAPEVLL-ELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENCKPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPFFDLLAQD</Hsp_qseq>
      <Hsp_hseq>EIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLL-VDPE-----------------TWSLKLCDFGSAKQLKPTEPNVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILG-TPSKQEICSMNPNYMEH------------KFPQIKPIPLSRVFKKED---DQTVEFLADVLKYDPLERFNALQCLCSPYFDELKLD</Hsp_hseq>
      <Hsp_midline>+++   +QL  ++ +LH    + H D+KP+N+L VD E                    +++ DFGSA      E + + + +R+YRAPE++     ++   D+WS GC++ E  LG  +F      + L  + + LG  PS+    +    Y  H            K+ +    PL R    +D    Q  + +  +L+Y+P +R    + L  P+FD L  D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>3.69183e-12</Hsp_evalue>
      <Hsp_query-from>933</Hsp_query-from>
      <Hsp_query-to>1478</Hsp_query-to>
      <Hsp_hit-from>202</Hsp_hit-from>
      <Hsp_hit-to>396</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>55</Hsp_gaps>
      <Hsp_align-len>216</Hsp_align-len>
      <Hsp_qseq>YHGHMCIAFELLGLST-----FDFLKENNYLPYPL-------HQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFG-SATFDYEHH-STIVSTRHYRAPEVLLELGWSQP-CDVWSIGCIVFEFYLGFTLFQ-------------------THDNREHLAMMERTLGLIPSRMVRRTRKQKYFHH</Hsp_qseq>
      <Hsp_hseq>YHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDS-------------------SEIKIIDFGLSNIYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKIKQGKVEYPQHLSIEVISLLSKMLVVDPKR--RATLKQVVEHH</Hsp_hseq>
      <Hsp_midline>YH H+C  FE+  LS      F+++     L Y +       HQ R  A  +  A+ +LH N + H DLK ENI+  DS                   ++I+++DFG S  +D      T   + ++ APE+L    ++ P  DVWS G ++F    G   F                     H + E ++++ + L + P R  R T KQ   HH</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>4.40732e-12</Hsp_evalue>
      <Hsp_query-from>906</Hsp_query-from>
      <Hsp_query-to>1721</Hsp_query-to>
      <Hsp_hit-from>93</Hsp_hit-from>
      <Hsp_hit-to>307</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>65</Hsp_gaps>
      <Hsp_align-len>276</Hsp_align-len>
      <Hsp_qseq>CVQMYDWFDYHGHMCIAFELLGLST-FDFLKENNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHH--STIVSTRHYRAPEVLLELGWSQ-PCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENCKPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPFFDLLAQDQRSAVRRDTPRD</Hsp_qseq>
      <Hsp_hseq>VLRLYDVWETNTDLYLVLEYAEKGELFNLLVERG--PLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLL-----DHKYN--------------IKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEED------------GNIRTLLLK-------VQKGEFE---------------------MPSDDEISREAQDLIRKILTVDPERRIKTRDILKHPLLQKYPSIRDSKSIRGLPRE</Hsp_hseq>
      <Hsp_midline> +++YD ++ +  + +  E       F+ L E    P P H+      Q+   + + H   + H DLKPEN+L      D KYN              I++ DFG A  + E     T   + HY APE++  + +     DVWS G I+F    G   F   D            G I + +++          G  +                     +  DD    +  DLI K+L  +P +RI   + LKHP        + S   R  PR+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YDL028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:400997:403291:-1 gene:YDL028C transcript:YDL028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MPS1 description:Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]</Hit_def>
  <Hit_accession>YDL028C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>5.32016e-12</Hsp_evalue>
      <Hsp_query-from>852</Hsp_query-from>
      <Hsp_query-to>1361</Hsp_query-to>
      <Hsp_hit-from>486</Hsp_hit-from>
      <Hsp_hit-to>650</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>190</Hsp_align-len>
      <Hsp_qseq>EINVLEKINEKDPRNKYLCVQMYDWFDYHGHMCIAFELLGLSTFDFLKENNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHHSTI-----VSTRHYRAPEVLLELGWSQ---------------PCDVWSIGCIVFEFYLG</Hsp_qseq>
      <Hsp_hseq>EIELLEKL-----KDQKRVIQLLDYEMGDGLLYLIMECGDHDLSQILNQRSGMPLDFNFVRFYTKEMLLCIKVVHDAGIVHSDLKPANFVLV--------------------KGILKIIDFGIANAVPEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYG</Hsp_hseq>
      <Hsp_midline>EI +LEK+     +++   +Q+ D+    G + +  E         L + + +P   + VR    ++   IK +HD  + H+DLKP N + V                       ++++DFG A    EH   I     + T +Y APE L+ + ++Q               P D+WS GCI+++   G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>7.16898e-12</Hsp_evalue>
      <Hsp_query-from>852</Hsp_query-from>
      <Hsp_query-to>1667</Hsp_query-to>
      <Hsp_hit-from>58</Hsp_hit-from>
      <Hsp_hit-to>295</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>278</Hsp_align-len>
      <Hsp_qseq>EINVLEKINEKDPRNKYLCVQMYDWFDYHGH-MCIAFELLGLSTFDFLKE-NNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSA---TFDYEHHSTIVSTRHYRAPEVLLELG-WSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENCKPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPFF</Hsp_qseq>
      <Hsp_hseq>EISLLKELKDDN------IVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLI-------------------NKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIVYLPDFKPSFPQWRR------------KDLSQVVPSLDPRG---IDLLDKLLAYDPINRISARRAAIHPYF</Hsp_hseq>
      <Hsp_midline>EI++L+++ + +       V++YD      H + + FE L L    +++      P     V+    QLC  I + H +++ H DLKP+N+L                     ++ ++++ DFG A         ++  + T  YRAPEVLL    +S   D WSIGCI  E      +F      + +  + R LG     +         F      W              K L + V   D +     DL++K+L Y+P  RI+   A  HP+F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>8.1233e-12</Hsp_evalue>
      <Hsp_query-from>933</Hsp_query-from>
      <Hsp_query-to>1670</Hsp_query-to>
      <Hsp_hit-from>181</Hsp_hit-from>
      <Hsp_hit-to>378</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>78</Hsp_gaps>
      <Hsp_align-len>261</Hsp_align-len>
      <Hsp_qseq>YHGHMCIAFELLGLST-----FDFLKENNYLPYPL-------HQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFG-SATFDYEHH-STIVSTRHYRAPEVLLELGWSQP-CDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENCKPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPFFD</Hsp_qseq>
      <Hsp_hseq>YHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSS-------------------GEIKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENS---------------SILHEKIKKGKVDYPSHLSIE-----------------------------VISLLTRMIVVDPLRRATLKNVVEHPWMN</Hsp_hseq>
      <Hsp_midline>YH H+C  FE+  +S      F+++     L Y +       H  R  A  +  A+++LH N + H DLK ENI+   S                    +I+++DFG S  FDY     T   + ++ APE+L    ++ P  D+WS G +++    G   F   ++               S +  + +K K  +  HL  +                             +  L+ +M+  +P +R TL   ++HP+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>1.98601e-11</Hsp_evalue>
      <Hsp_query-from>969</Hsp_query-from>
      <Hsp_query-to>1373</Hsp_query-to>
      <Hsp_hit-from>152</Hsp_hit-from>
      <Hsp_hit-to>265</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>135</Hsp_align-len>
      <Hsp_qseq>GLSTFDFLKENNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLF</Hsp_qseq>
      <Hsp_hseq>GGELFSLLRKSQRFPNPV--AKFYAAEVILALEYLHAHNIIYRDLKPENILLD-------------------RNGHIKITDFGFAKEVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPF</Hsp_hseq>
      <Hsp_midline>G   F  L+++   P P+   +  A ++  A+++LH + + + DLKPENIL                     RN  I++ DFG A        T+  T  Y APEV+    +++  D WS+G +++E   G+T F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>3.07349e-11</Hsp_evalue>
      <Hsp_query-from>906</Hsp_query-from>
      <Hsp_query-to>1706</Hsp_query-to>
      <Hsp_hit-from>247</Hsp_hit-from>
      <Hsp_hit-to>494</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>118</Hsp_positive>
      <Hsp_gaps>65</Hsp_gaps>
      <Hsp_align-len>290</Hsp_align-len>
      <Hsp_qseq>CVQMYDWFDYH---GHMCIAFELL-GLSTFDFLKENNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNAD---------------IRVVDFG-SATFDYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENCKPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPF---FDLLAQDQRSAVRR</Hsp_qseq>
      <Hsp_hseq>CSQIVAFIDFQETDSYYYIIQELLTGGEIFGEIVRLTYFSEDLS--RHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKNTKTPCGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTMLCGFPPF--YDEK------------IDTLTEKISRGEYTFLKPW--WDEISAGAK------------------------NAVAKLLELEPSKRYDIDQFLDDPWLNTFDCLPKEGESSQKK</Hsp_hseq>
      <Hsp_midline>C Q+  + D+     +  I  ELL G   F  +    Y    L   R +  QL  A+K +H   + H D+KPEN+LF   E+     P+ ++ +     AD               +++ DFG S     ++  T   T  Y APEV+ +  +S   D+W IGC+++    GF  F  +D +            I +   + +R +  F      WDE S+  K                        + + K+L+ EPSKR  + + L  P+   FD L ++  S+ ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>7.06591e-11</Hsp_evalue>
      <Hsp_query-from>906</Hsp_query-from>
      <Hsp_query-to>1667</Hsp_query-to>
      <Hsp_hit-from>66</Hsp_hit-from>
      <Hsp_hit-to>290</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>53</Hsp_gaps>
      <Hsp_align-len>266</Hsp_align-len>
      <Hsp_qseq>CVQMYDWFDYHGHMCIAFELLGLSTFDFLKENNYL--PYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHHSTIVS---TRHYRAPEVLLELG-WSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENCKP------LRRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPFF</Hsp_qseq>
      <Hsp_hseq>VIELIDIFMAYDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVY---HCHRNFILHRDLKPNNLLFSP-------------------DGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDR----------------DWPEVSSFMTYNKLQIYPPPSRDELRKRFI---AASEYALDFMCGMLTMNPQKRWTAVQCLESDYF</Hsp_hseq>
      <Hsp_midline> +++ D F  + ++ +  E L       +K+ + L  P  +    LM  +  Y     H N + H DLKP N+LF                     +  I+V DFG A      H  + S   TR YRAPE+L     ++   D+WS+G I  E  L        ++ + + +  R LG    R                DW E SS   Y +    P      LR+  +   A      D +  ML   P KR T  + L+  +F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>8.51137e-11</Hsp_evalue>
      <Hsp_query-from>906</Hsp_query-from>
      <Hsp_query-to>1667</Hsp_query-to>
      <Hsp_hit-from>176</Hsp_hit-from>
      <Hsp_hit-to>369</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>72</Hsp_gaps>
      <Hsp_align-len>260</Hsp_align-len>
      <Hsp_qseq>CVQMYDWFDYHGHMCIAFELL-GLSTFDFLKENNYLPY--PLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHH--STIVSTRHYRAPEVLLELGW-SQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENCKPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPFF</Hsp_qseq>
      <Hsp_hseq>VMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFK----QIVEGVSYCHSFNICHRDLKPENLLL------------DKKNRR------IKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMPSNLSSEAR--------------------------------------------DLISKILVIDPEKRITTQEILKHPLI</Hsp_hseq>
      <Hsp_midline> + +++ ++    + +  E + G   FD+L     LP    +H  +    Q+   + + H   + H DLKPEN+L              K++ R      I++ DFG A  +  +    T   + HY +PE+++   +   P DVWS G ++F    G   F   + ++ L  ++     +PS +    R                                            DLI K+L  +P KRIT  E LKHP  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>8.66304e-11</Hsp_evalue>
      <Hsp_query-from>1047</Hsp_query-from>
      <Hsp_query-to>1394</Hsp_query-to>
      <Hsp_hit-from>521</Hsp_hit-from>
      <Hsp_hit-to>619</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>118</Hsp_align-len>
      <Hsp_qseq>QLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHHS-TIVSTRHYRAPEVLL-ELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNRE</Hsp_qseq>
      <Hsp_hseq>ELVLALEHLHDNDIVYRDLKPENIL-LDA------------------NGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQK</Hsp_hseq>
      <Hsp_midline>+L  A++ LHDN + + DLKPENIL +D+                  N +I + DFG +  D +  + T   T  Y APE+LL E G+++  D WS+G ++FE   G++ F   +N++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>1.80262e-10</Hsp_evalue>
      <Hsp_query-from>846</Hsp_query-from>
      <Hsp_query-to>1409</Hsp_query-to>
      <Hsp_hit-from>603</Hsp_hit-from>
      <Hsp_hit-to>780</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>197</Hsp_align-len>
      <Hsp_qseq>RLEINVLEKINEKDPRNKYLCVQMYDWFDYHGHMCIAFELL-GLSTFDFLK-----ENNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFG---SATFDYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMM</Hsp_qseq>
      <Hsp_hseq>RKELIVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLL---------------DTR----ARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLI</Hsp_hseq>
      <Hsp_midline>R E+ V E +  KD R+K +   +  +      + +  E + G S  D ++     +N++ P    Q+  +  + C  +KFLHD  + H D+K +N+L                D R    A +++ DFG     T      +T+V T ++ APEV+ +  + +  DVWS+G +  E   G   +   D  + L ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>1.83565e-10</Hsp_evalue>
      <Hsp_query-from>1020</Hsp_query-from>
      <Hsp_query-to>1430</Hsp_query-to>
      <Hsp_hit-from>144</Hsp_hit-from>
      <Hsp_hit-to>286</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>145</Hsp_align-len>
      <Hsp_qseq>LHQVRLMAY--QLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERT---VRNADI-RVVDFGSATF--DYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLI</Hsp_qseq>
      <Hsp_hseq>LHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLL--STPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVVFEMCCGTPPFRASNHLELFKKIKRANDVI</Hsp_hseq>
      <Hsp_midline>LH+  +++Y  QL  A+KFL    L H D+KP+N+L   S   I Y+  K   E     + N  I ++ DFG A F  +     T+  +  Y APE+L    ++   D+WS+G +VFE   G   F+  ++ E    ++R   +I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YIL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:287790:288908:-1 gene:YIL035C transcript:YIL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA1 description:Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000001297]</Hit_def>
  <Hit_accession>YIL035C</Hit_accession>
  <Hit_len>372</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>2.15327e-10</Hsp_evalue>
      <Hsp_query-from>1026</Hsp_query-from>
      <Hsp_query-to>1667</Hsp_query-to>
      <Hsp_hit-from>171</Hsp_hit-from>
      <Hsp_hit-to>363</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>QVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEH--HSTIVSTRHYRAPEVLLEL-GWSQPCDVWSIGCIVFEFYLGF-TLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWD-ESSSAGKYVRENCKPLRRYVVCDDAQHH-----QLFDLIEKMLQYEPSKRITLGEALKHPFF</Hsp_qseq>
      <Hsp_hseq>EIRFYMFELLKALDYCHSMGIMHRDVKPHNVM-IDH-----------------KNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLG--------TSDFEKYLLKYEITLPREFYDMDQYIR---KPWHRFI--NDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWF</Hsp_hseq>
      <Hsp_midline>++R   ++L  A+ + H   + H D+KP N++ +D                  +N  +R++D+G A F + +  ++  V++R ++ PE+L++   +    D+WS G ++          F    N + L  + + LG         +  +KY     +    E     +Y+R   KP  R++  +D   H     ++ DLI+ +L+Y+  +R+T  EA+ HP+F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YOR061W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:441534:442553:1 gene:YOR061W transcript:YOR061W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA2 description:Alpha&apos; catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000005587]</Hit_def>
  <Hit_accession>YOR061W</Hit_accession>
  <Hit_len>339</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>2.60897e-10</Hsp_evalue>
      <Hsp_query-from>1005</Hsp_query-from>
      <Hsp_query-to>1667</Hsp_query-to>
      <Hsp_hit-from>136</Hsp_hit-from>
      <Hsp_hit-to>334</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>227</Hsp_align-len>
      <Hsp_qseq>YLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEH--HSTIVSTRHYRAPEVLLELG-WSQPCDVWSIGCIVFEF-YLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENCKPLRRYVVCDDAQHH--QLFDLIEKMLQYEPSKRITLGEALKHPFF</Hsp_qseq>
      <Hsp_hseq>YPTFKLPDIQYYFTQLLIALDYCHSMGIMHRDVKPQNVMI---------DPTERK---------LRLIDWGLAEFYHPGVDYNVRVASRYHKGPELLVNLNQYDYSLDLWSVGCMLAAIVFKKEPFFKGSSNPDQLVKIATVLG----------TKELLGYLGKYGLHLPSEYDNIMRDFTKKSWTHFITSETKLAVPEVVDLIDNLLRYDHQERLTAKEAMDHKFF</Hsp_hseq>
      <Hsp_midline>Y  + L  ++    QL  A+ + H   + H D+KP+N++          +P +++         +R++D+G A F +    ++  V++R+++ PE+L+ L  +    D+WS+GC++    +     F+   N + L  +   LG           K+   + G       S     +R+  K    + +  + +    ++ DLI+ +L+Y+  +R+T  EA+ H FF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>7.39502e-10</Hsp_evalue>
      <Hsp_query-from>1029</Hsp_query-from>
      <Hsp_query-to>1670</Hsp_query-to>
      <Hsp_hit-from>115</Hsp_hit-from>
      <Hsp_hit-to>294</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>74</Hsp_gaps>
      <Hsp_align-len>234</Hsp_align-len>
      <Hsp_qseq>VRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSA--------------------TFDYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENCKPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPFFD</Hsp_qseq>
      <Hsp_hseq>TRHFTAQLIDALEFIHSHGIIHRDLKPENVLL-------------DRDGR------LMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPFRGEN---ELKTFEKIVAL----------------------DYPWGPNNRINNSTSPINPLVI----------NLVQKILVIEVNERISLEQIKRHPYFS</Hsp_hseq>
      <Hsp_midline> R    QL  A++F+H + + H DLKPEN+L               RD R      + + DFG+A                    + D ++ ++ V T  Y +PE+LL        D+W++GC++++F  G   F+  +    L   E+ + L                      D        +  +  P+   V+          +L++K+L  E ++RI+L +  +HP+F </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>7.67537e-10</Hsp_evalue>
      <Hsp_query-from>1029</Hsp_query-from>
      <Hsp_query-to>1385</Hsp_query-to>
      <Hsp_hit-from>280</Hsp_hit-from>
      <Hsp_hit-to>393</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>133</Hsp_align-len>
      <Hsp_qseq>VRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSAT-------------FDYEHHS-TIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLFQTHD</Hsp_qseq>
      <Hsp_hseq>ARYYAAQIIDAIDYLHSNGIIHRDIKPENIL-LDGEMKIK------------------LTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATN</Hsp_hseq>
      <Hsp_midline> R  A Q+  AI +LH N + H D+KPENIL +D E  IK                  + DFG+A              +D    S + V T  Y +PE+L +      CD+W+ GCI+F+   G   F+  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>1.31232e-09</Hsp_evalue>
      <Hsp_query-from>1011</Hsp_query-from>
      <Hsp_query-to>1361</Hsp_query-to>
      <Hsp_hit-from>478</Hsp_hit-from>
      <Hsp_hit-to>578</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>120</Hsp_align-len>
      <Hsp_qseq>PYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFG---SATFDYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLG</Hsp_qseq>
      <Hsp_hseq>PLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILL---------NSQ----------GLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEG</Hsp_hseq>
      <Hsp_midline>P   +Q+  +  + C  +KFLH+ K+ H D+K +NIL          N Q            +++ DFG     T      +T+V T ++ APE++ + G+ +  DVWS+G ++ E   G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>3.22896e-09</Hsp_evalue>
      <Hsp_query-from>906</Hsp_query-from>
      <Hsp_query-to>1721</Hsp_query-to>
      <Hsp_hit-from>89</Hsp_hit-from>
      <Hsp_hit-to>303</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>69</Hsp_gaps>
      <Hsp_align-len>278</Hsp_align-len>
      <Hsp_qseq>CVQMYDWFDYHGHMCIAFELLGLST-FDFLKENNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATF--DYEHHSTIVSTRHYRAPEVLLELGWSQ-PCDVWSIGCIVFEFYLGFTLFQTHDN--REHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENCKPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPFFDLLAQDQRSAVRRDTPRD</Hsp_qseq>
      <Hsp_hseq>VLSLYDVWETNNNLYLILEYAEKGELFNLLVDHG--PLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLL-DSFYNIK------------------IADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQK--------------------------------GQFEMPNDTEISR-----DAQ-----DLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRE</Hsp_hseq>
      <Hsp_midline> + +YD ++ + ++ +  E       F+ L ++   P P  +      Q+   I + H   + H DLKPEN+L  DS Y+IK                  + DFG A    D +   T   + HY APE++  L +     DVWS G I+F    G   F   +   R+ L  +++                                G++   N   + R     DAQ     DLI K+L  +P +RI + + L HP        + S   +D PR+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>3.84186e-09</Hsp_evalue>
      <Hsp_query-from>1041</Hsp_query-from>
      <Hsp_query-to>1535</Hsp_query-to>
      <Hsp_hit-from>1139</Hsp_hit-from>
      <Hsp_hit-to>1290</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>174</Hsp_align-len>
      <Hsp_qseq>AYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKY------NPQKKRDERTVRNADIRVVDFGSATFDYEHHSTIVSTRHYRAPEVL---LELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENC</Hsp_qseq>
      <Hsp_hseq>TFELLEGLAYLHQSGVVHRDIKPENIL-LDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQ--DFGVET---KSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPWSNLDN-EWAIMYHVAAGRIPQLPNR---------------DEMTAAGRAFLERC</Hsp_hseq>
      <Hsp_midline> ++L   + +LH + + H D+KPENIL +D    IKY              RTVRNA ++  DFG  T   +  + ++ T  Y APE +      G     DVW++GC+V E   G   +   DN E   M     G IP    R               DE ++AG+   E C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>6.04388e-09</Hsp_evalue>
      <Hsp_query-from>1017</Hsp_query-from>
      <Hsp_query-to>1667</Hsp_query-to>
      <Hsp_hit-from>259</Hsp_hit-from>
      <Hsp_hit-to>463</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>228</Hsp_align-len>
      <Hsp_qseq>PLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHHST------IVSTRHYRAPEVLLELGWSQPC-DVWSIGCIVFEFYLGFTLFQTH----DNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENCKPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPFF</Hsp_qseq>
      <Hsp_hseq>PPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTI-------------------DGCVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELIGLQPIFKGEEAKLDSKKTVPFQVNQLQRILEVLGTPDQKIWPYLEKYPEYDQITKFPKY-RDN---LATWYHSAGGRDKHALSLLYHLLNYDPIKRIDAFNALEHKYF</Hsp_hseq>
      <Hsp_midline>P   VR + +QL   + +LH N + H DLKP NI+                      +  +++ D G A   +    T      +V T  YRAPE+LL      P  D+WS+GCI  E      +F+      D+++ +      L  I   +    +K   +   + ++D+ +   KY R+N   L  +      +      L+  +L Y+P KRI    AL+H +F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>7.06346e-09</Hsp_evalue>
      <Hsp_query-from>1029</Hsp_query-from>
      <Hsp_query-to>1667</Hsp_query-to>
      <Hsp_hit-from>598</Hsp_hit-from>
      <Hsp_hit-to>777</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>55</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>VRLMAYQLCYAIKFLHDNKLTHTDLKPENILF------VDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLA-MMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENCKPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRI--TLGEA--LKHPFF</Hsp_qseq>
      <Hsp_hseq>ARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNS-FVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKNEVSFPNNNEISRT--------------------------CK-----------------DLIKKLLTKNESKRLGCKMGAADVKKHPFF</Hsp_hseq>
      <Hsp_midline> R  A ++  A+++LH     + DLKPENIL       + S++D+    +  +      +A   +VD    +  +  +S  V T  Y APEV+   G +   D W++G +++E   GFT F+  +  E    +++  +    +  + RT                          CK                 DLI+K+L    SKR+   +G A   KHPFF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>7.36561e-09</Hsp_evalue>
      <Hsp_query-from>1044</Hsp_query-from>
      <Hsp_query-to>1667</Hsp_query-to>
      <Hsp_hit-from>209</Hsp_hit-from>
      <Hsp_hit-to>355</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>65</Hsp_gaps>
      <Hsp_align-len>210</Hsp_align-len>
      <Hsp_qseq>YQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHH--STIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENCKPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPFF</Hsp_qseq>
      <Hsp_hseq>YQIANALDYMHKKNIIHRDIKPENIL-------IGF------------NNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPPFEEE-----------------------MKDTTYKRIAALDIKMPSN----------------ISQDAQ-----DLILKLLKYDPKDRMRLGDVKMHPWI</Hsp_hseq>
      <Hsp_midline>YQ+  A+ ++H   + H D+KPENIL       I +            N  I++ DFG +  +   +   T+  T  Y +PE++    +    D W++G + FE   G   F+                          +   Y     LD    S+                +  DAQ     DLI K+L+Y+P  R+ LG+   HP+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>9.42771e-09</Hsp_evalue>
      <Hsp_query-from>1029</Hsp_query-from>
      <Hsp_query-to>1385</Hsp_query-to>
      <Hsp_hit-from>226</Hsp_hit-from>
      <Hsp_hit-to>341</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>123</Hsp_align-len>
      <Hsp_qseq>VRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIK---YNPQKKRDERTVRNADIRVVDFGSATFD-YEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLFQTHD</Hsp_qseq>
      <Hsp_hseq>ARYYASQIIDAVDSLHNIGIIHRDIKPENIL-LDKNMKVKLTDFGTAKILPEEPSNTAD------GKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAAN</Hsp_hseq>
      <Hsp_midline> R  A Q+  A+  LH+  + H D+KPENIL +D    +K   +   K   E     AD      G   FD Y    + V T  Y +PE+L +      CD+W+ GCI+++   G   F+  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>9.92023e-09</Hsp_evalue>
      <Hsp_query-from>1026</Hsp_query-from>
      <Hsp_query-to>1424</Hsp_query-to>
      <Hsp_hit-from>282</Hsp_hit-from>
      <Hsp_hit-to>398</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>139</Hsp_align-len>
      <Hsp_qseq>QVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFG-----SATFDYEHHSTIVSTRHYRAPEVLL-ELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLG</Hsp_qseq>
      <Hsp_hseq>QCKHLFKQLLLGMEYLHDNKILHRDVKGSNIL-IDNQ------------------GNLKITDFGLARKMNSRADYTNR---VITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMG</Hsp_hseq>
      <Hsp_midline>Q + +  QL   +++LHDNK+ H D+K  NIL +D++                   ++++ DFG     ++  DY +    V T  YR PE+LL    +    D+W  GC++ E +    +FQ  +  E +  + + +G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>1.94054e-08</Hsp_evalue>
      <Hsp_query-from>1029</Hsp_query-from>
      <Hsp_query-to>1667</Hsp_query-to>
      <Hsp_hit-from>426</Hsp_hit-from>
      <Hsp_hit-to>602</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>60</Hsp_gaps>
      <Hsp_align-len>225</Hsp_align-len>
      <Hsp_qseq>VRLMAYQLCYAIKFLHDNKLTHTDLKPENILF--------VDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENCKPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRI----TLGEALKHPFF</Hsp_qseq>
      <Hsp_hseq>AKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRT------NSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNI-------------LTKDVKFPHD------------KEVSKNCK-----------------DLIKKLLNKNEAKRLGSKSGAADIKRHPFF</Hsp_hseq>
      <Hsp_midline> +  A ++  A+++LH     + DLKPENIL          D +  I+    KK   +     D ++   G  T      ++ V T  Y APEV+   G +   D W++G +++E   G T F+  ++ E  + +              T+  K+ H             K V +NCK                 DLI+K+L    +KR+       +  +HPFF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>2.23103e-08</Hsp_evalue>
      <Hsp_query-from>1029</Hsp_query-from>
      <Hsp_query-to>1415</Hsp_query-to>
      <Hsp_hit-from>236</Hsp_hit-from>
      <Hsp_hit-to>370</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>135</Hsp_align-len>
      <Hsp_qseq>VRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADI-----RVVDFGSAT-FDYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMER</Hsp_qseq>
      <Hsp_hseq>ARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLRNNTAKTPCGTIEYVASEVFTSKRYSMKVDMWSIGCVLFTLLCGYPPFYEKNEKTLLKKISR</Hsp_hseq>
      <Hsp_midline> R +  Q+  AIK +H   + H D+KPEN+LF    +       +K DE T+          +++DFG A         T   T  Y A EV     +S   D+WSIGC++F    G+  F   + +  L  + R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>2.25765e-08</Hsp_evalue>
      <Hsp_query-from>852</Hsp_query-from>
      <Hsp_query-to>1346</Hsp_query-to>
      <Hsp_hit-from>1149</Hsp_hit-from>
      <Hsp_hit-to>1295</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>EINVLEKINEKDPRNKYLCVQMYDWFD----YHGHMCIAFELLGLSTFDFLK-ENNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATF-DYEHHSTIVSTRHYRAPEVLLELGW-SQPCDVWSIGCIVF</Hsp_qseq>
      <Hsp_hseq>EIQIMATLNKKPHEN---ILRLLDFFEDDDYYYIETPVHGETGCIDLFDLIEFKTNMTEF---EAKLIFKQVVAGIKHLHDQGIVHRDIKDENVI-VDSK------------------GFVKIIDFGSAAYVKSGPFDVFVGTIDYAAPEVLGGNPYEGQPQDIWAIGILLY</Hsp_hseq>
      <Hsp_midline>EI ++  +N+K   N    +++ D+F+    Y+    +  E   +  FD ++ + N   +   + +L+  Q+   IK LHD  + H D+K EN++ VDS+                    ++++DFGSA +         V T  Y APEVL    +  QP D+W+IG +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>4.84276e-08</Hsp_evalue>
      <Hsp_query-from>1029</Hsp_query-from>
      <Hsp_query-to>1361</Hsp_query-to>
      <Hsp_hit-from>254</Hsp_hit-from>
      <Hsp_hit-to>358</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>117</Hsp_align-len>
      <Hsp_qseq>VRLMAYQLCYAIKFLHDNKLTHTDLKPENILF------VDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLG</Hsp_qseq>
      <Hsp_hseq>VSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLS---KKSANDSAVDEEDPENVN---ALY------SIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVG</Hsp_hseq>
      <Hsp_midline>V   A ++  A++FLH   + + DLKPEN L       V +++ +    +K  ++  V   D   V+   A +      +I+ T  Y APE+LL   +SQ CD +S+GC++++  +G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>5.07189e-08</Hsp_evalue>
      <Hsp_query-from>828</Hsp_query-from>
      <Hsp_query-to>1361</Hsp_query-to>
      <Hsp_hit-from>496</Hsp_hit-from>
      <Hsp_hit-to>653</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>185</Hsp_align-len>
      <Hsp_qseq>KYREAARLEINVLEKINEKDPRNKYLCVQMYDWFDYHGHMCIAFELL-GLSTFDFLKENNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSA------TFDYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLG</Hsp_qseq>
      <Hsp_hseq>KMVDALQHEMNLLKELHHEN------IVTYYGASQEGGNLNIFLEYVPGGSVSSML--NNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILI-----DIK--------------GCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTG</Hsp_hseq>
      <Hsp_midline>K  +A + E+N+L++++ ++       V  Y      G++ I  E + G S    L  NNY P+    +     Q+   + +LH   + H D+K  NIL      DIK                +++ DFG +             +++  +  + +PEV+ +   +   D+WS GC+V E + G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>5.24682e-08</Hsp_evalue>
      <Hsp_query-from>906</Hsp_query-from>
      <Hsp_query-to>1346</Hsp_query-to>
      <Hsp_hit-from>115</Hsp_hit-from>
      <Hsp_hit-to>243</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>150</Hsp_align-len>
      <Hsp_qseq>CVQMYDWFDYHGHMCIAFELLGLSTFDFLKENNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATF--DYEHHSTIVSTRHYRAPEVLLELGWSQP-CDVWSIGCIVF</Hsp_qseq>
      <Hsp_hseq>IIKLYDVIKSKDEIIMVIEYAGNELFDYIVQRDKMSE--QEARRFFQQIISAVEYCHRHKIVHRDLKPENLLL---------------DE----HLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILY</Hsp_hseq>
      <Hsp_midline> +++YD       + +  E  G   FD++ + + +     + R    Q+  A+++ H +K+ H DLKPEN+L                DE    + ++++ DFG +    D     T   + +Y APEV+    ++ P  DVWS G I++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>6.04924e-08</Hsp_evalue>
      <Hsp_query-from>909</Hsp_query-from>
      <Hsp_query-to>1412</Hsp_query-to>
      <Hsp_hit-from>274</Hsp_hit-from>
      <Hsp_hit-to>428</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>176</Hsp_align-len>
      <Hsp_qseq>VQMYDWF--DYHGHMCIAFELLGLSTF-----DFLKENNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFG-SATFDYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMME</Hsp_qseq>
      <Hsp_hseq>VQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERV--IGKIAESVLRGLSYLHERKVIHRDIKPQNILLNE-------------------KGEIKLCDFGVSGEAVNSLAMTFTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRFPFESDKITQNVAPIE</Hsp_hseq>
      <Hsp_midline>VQ Y  F  +    + IA E +G  +      + LK    +   +  +  +A  +   + +LH+ K+ H D+KP+NIL  +                     +I++ DFG S         T   T  Y APE +    +S  CDVWS+G  + E   G   F++    +++A +E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>6.81176e-08</Hsp_evalue>
      <Hsp_query-from>852</Hsp_query-from>
      <Hsp_query-to>1346</Hsp_query-to>
      <Hsp_hit-from>894</Hsp_hit-from>
      <Hsp_hit-to>1040</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>171</Hsp_align-len>
      <Hsp_qseq>EINVLEKINEKDPRNKYLCVQMYDWFD----YHGHMCIAFELLGLSTFDFLKENNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATF-DYEHHSTIVSTRHYRAPEVLLELGW-SQPCDVWSIGCIVF</Hsp_qseq>
      <Hsp_hseq>EIQIMATLNKNSQEN---ILKLLDFFEDDDYYYIETPVHGETGSIDLFDVIEFKKDMVE--HEAKLVFKQVVASIKHLHDQGIVHRDIKDENVI-VDS------------------HGFVKLIDFGSAAYIKSGPFDVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLY</Hsp_hseq>
      <Hsp_midline>EI ++  +N+    N    +++ D+F+    Y+    +  E   +  FD ++    +    H+ +L+  Q+  +IK LHD  + H D+K EN++ VDS                  +  ++++DFGSA +         V T  Y APEVL    +  +P D+W++G +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>7.14769e-08</Hsp_evalue>
      <Hsp_query-from>1029</Hsp_query-from>
      <Hsp_query-to>1667</Hsp_query-to>
      <Hsp_hit-from>172</Hsp_hit-from>
      <Hsp_hit-to>366</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>54</Hsp_gaps>
      <Hsp_align-len>231</Hsp_align-len>
      <Hsp_qseq>VRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDY---------------EHHSTIVSTRHYRAPEVLL-ELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESS--SAGKYVRENCKPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPFF</Hsp_qseq>
      <Hsp_hseq>IKNMMLQILEGLNYIHCAKFMHRDIKTANIL-ID------------------HNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLG-TPTEE---------------DWAVARYLPGAELTTTNYKPTLRERFGKYLSETGL-DFLGQLLALDPYKRLTAMSAKHHPWF</Hsp_hseq>
      <Hsp_midline>++ M  Q+   + ++H  K  H D+K  NIL +D                   N  +++ DFG A   Y                 ++++V TR YRAPE++L +  ++   D+W +GC+  EF+    + Q   + +   ++ + LG  P+                 DW  +      +    N KP  R           L D + ++L  +P KR+T   A  HP+F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YAR018C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:170396:171703:-1 gene:YAR018C transcript:YAR018C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN3 description:Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol [Source:SGD;Acc:S000000071]</Hit_def>
  <Hit_accession>YAR018C</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>8.26428e-08</Hsp_evalue>
      <Hsp_query-from>1080</Hsp_query-from>
      <Hsp_query-to>1352</Hsp_query-to>
      <Hsp_hit-from>168</Hsp_hit-from>
      <Hsp_hit-to>281</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>53</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>114</Hsp_align-len>
      <Hsp_qseq>NKLTHTDLKPENILFV--DSEYDI------------------KYNPQKKRDERTVRNADIRVVDFG---SATFDYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEF</Hsp_qseq>
      <Hsp_hseq>NIVIHRDLKPGNIFLSYDDSDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLAKSLETSIQFATTYVGTPYYMSPEVLMDQPYSPLSDIWSLGCVIFEM</Hsp_hseq>
      <Hsp_midline>N + H DLKP NI     DS+Y+I                  + N  K+          +++ DFG   S     +  +T V T +Y +PEVL++  +S   D+WS+GC++FE </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>2.06884e-07</Hsp_evalue>
      <Hsp_query-from>837</Hsp_query-from>
      <Hsp_query-to>1394</Hsp_query-to>
      <Hsp_hit-from>867</Hsp_hit-from>
      <Hsp_hit-to>1031</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>190</Hsp_align-len>
      <Hsp_qseq>EAARLEINV-LEKINEKDPRNKYLCVQMYDWFDYHGHMCIAFELLGLSTFDFLKENNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDY---EHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNRE</Hsp_qseq>
      <Hsp_hseq>ESARAEKKVFLLATKTKHP----FLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQRLS--VRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGH-------------------IKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDE</Hsp_hseq>
      <Hsp_midline>E+AR E  V L     K P        +Y  F     +  A E +G     +  +N  L   + + +  A ++  A+K+ HDN + + DLK ENIL     +                   I++ D+G    +       ST   T  + APE+L E  +++  D W+ G ++++  L  + F   D  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>2.48937e-07</Hsp_evalue>
      <Hsp_query-from>909</Hsp_query-from>
      <Hsp_query-to>1373</Hsp_query-to>
      <Hsp_hit-from>224</Hsp_hit-from>
      <Hsp_hit-to>385</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>178</Hsp_align-len>
      <Hsp_qseq>VQMYDWF-DYHGHMCIAFELL-GLSTFDFLKENNYL-PYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSA---TFDYEHHSTIVSTRHYRAPEV-----------------LLELGWSQPCDVWSIGCIVFEFYLGFTLF</Hsp_qseq>
      <Hsp_hseq>IKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPE------PCTR----------IVLADFGIAKDLNSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGISPF</Hsp_hseq>
      <Hsp_midline>+++Y  F D + H+ I  +L+ G   F +L + + L      +  L+ +Q+  A+ +LHD  + H DLK +NIL    E      P  +          I + DFG A     + E   T+V T  Y APEV                 L + G+   CD+WS+G I      G + F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>3.05547e-07</Hsp_evalue>
      <Hsp_query-from>909</Hsp_query-from>
      <Hsp_query-to>1385</Hsp_query-to>
      <Hsp_hit-from>87</Hsp_hit-from>
      <Hsp_hit-to>221</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>161</Hsp_align-len>
      <Hsp_qseq>VQMYDWFDYHGHMCIAFELLGLSTFDFLKENNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHHSTIVSTRHYRAPEVL-LEL-GWSQPCDVWSIGCIVFEFYLGFTLFQTHD</Hsp_qseq>
      <Hsp_hseq>VSMWIVMEYCG---------GGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILL--------------NEEGMVKLGDFGVSGHIRSTL---KRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPPLSKYD</Hsp_hseq>
      <Hsp_midline>V M+   +Y G         G S  D LK +     P  +V  + +++   +K+LH+ +  H D+K  NIL                +E  V+  D  V     +T       T V T ++ APEV+  E+ G+++  D+WS+G   +E   G      +D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>3.14451e-07</Hsp_evalue>
      <Hsp_query-from>1047</Hsp_query-from>
      <Hsp_query-to>1394</Hsp_query-to>
      <Hsp_hit-from>116</Hsp_hit-from>
      <Hsp_hit-to>229</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>133</Hsp_align-len>
      <Hsp_qseq>QLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHHSTIVSTRHYRAPEVL-----------------LELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNRE</Hsp_qseq>
      <Hsp_hseq>QLCSAISFAHSLGIAHRDIKPENILL-------------------TINGDIKLADWGHAIQSPKSNDFQIGTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFGDCLFRVSKSKK</Hsp_hseq>
      <Hsp_midline>QLC AI F H   + H D+KPENIL                      N DI++ D+G A    + +   + T +YRAPE                     L  +   D WS+G  +F    G  LF+   +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YFL029C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:78055:79161:-1 gene:YFL029C transcript:YFL029C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CAK1 description:Cyclin-dependent kinase-activating kinase; required for passage through the cell cycle; phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases [Source:SGD;Acc:S000001865]</Hit_def>
  <Hit_accession>YFL029C</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>3.57362e-07</Hsp_evalue>
      <Hsp_query-from>1047</Hsp_query-from>
      <Hsp_query-to>1355</Hsp_query-to>
      <Hsp_hit-from>139</Hsp_hit-from>
      <Hsp_hit-to>238</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>115</Hsp_align-len>
      <Hsp_qseq>QLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHHS-----------TIVSTRHYRAPEVLLELG-WSQPCDVWSIGCIVFEFY</Hsp_qseq>
      <Hsp_hseq>QMVEGIAFLHENKIIHRDIKPQNIMLTNNTSTV--------------SPKLYIIDFG-ISYDMANNSQTSAEPMDSKVTDISTGIYKAPEVLFGVKCYDGGVDVWSLLIIISQWF</Hsp_hseq>
      <Hsp_midline>Q+   I FLH+NK+ H D+KP+NI+  ++   +              +  + ++DFG  ++D  ++S           T +ST  Y+APEVL  +  +    DVWS+  I+ +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>5.52607e-07</Hsp_evalue>
      <Hsp_query-from>1014</Hsp_query-from>
      <Hsp_query-to>1385</Hsp_query-to>
      <Hsp_hit-from>442</Hsp_hit-from>
      <Hsp_hit-to>549</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>127</Hsp_align-len>
      <Hsp_qseq>YPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATF---DYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLFQTHD</Hsp_qseq>
      <Hsp_hseq>FDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILL---DY----------------QGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDED</Hsp_hseq>
      <Hsp_midline>+ L + R    +L  A+  LH   + + DLKPENIL    +Y                   I + DFG       D +   T   T  Y APE+LL LG+++  D W++G +++E   G   +   D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>1.3039e-06</Hsp_evalue>
      <Hsp_query-from>909</Hsp_query-from>
      <Hsp_query-to>1361</Hsp_query-to>
      <Hsp_hit-from>281</Hsp_hit-from>
      <Hsp_hit-to>418</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>157</Hsp_align-len>
      <Hsp_qseq>VQMYDWF--DYHGHMCIAFELLGLSTFDFLKENNYLPYPLHQVRLM---AYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFG-SATFDYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLG</Hsp_qseq>
      <Hsp_hseq>VRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNE-------------------NGQVKLCDFGVSGEAVNSLATTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANG</Hsp_hseq>
      <Hsp_midline>V+ Y  F  D +  + IA E +G  + D + +N          +++   A  +   + +LH+ K+ H D+KP+NIL  +                   N  +++ DFG S        +T   T  Y APE +    +S   DVWS+G  + E   G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YKL168C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:131288:133462:-1 gene:YKL168C transcript:YKL168C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KKQ8 description:Putative serine/threonine protein kinase with unknown cellular role; KKQ8 has a paralog, HAL5, that arose from the whole genome duplication [Source:SGD;Acc:S000001651]</Hit_def>
  <Hit_accession>YKL168C</Hit_accession>
  <Hit_len>724</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>1.5214e-06</Hsp_evalue>
      <Hsp_query-from>1047</Hsp_query-from>
      <Hsp_query-to>1403</Hsp_query-to>
      <Hsp_hit-from>546</Hsp_hit-from>
      <Hsp_hit-to>654</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>128</Hsp_align-len>
      <Hsp_qseq>QLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATF-------DYEHHSTIVSTRHYRAPEVLLELGWSQP--CDVWSIGCIVFEFYLGFTLFQTHDNREHLA</Hsp_qseq>
      <Hsp_hseq>QLLHGVKFMHDHGIAHCDLKPENILFYP-------------------HGLLKICDFGTSSVFQTAWERRVHAQKGIIGSEPYVAPEEFVDGEYYDPRLIDCWSCGVVYITMILGHYLWKVASREKDMS</Hsp_hseq>
      <Hsp_midline>QL + +KF+HD+ + H DLKPENILF                     +  +++ DFG+++               I+ +  Y APE  ++  +  P   D WS G +     LG  L++     + ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>1.99841e-06</Hsp_evalue>
      <Hsp_query-from>891</Hsp_query-from>
      <Hsp_query-to>1394</Hsp_query-to>
      <Hsp_hit-from>233</Hsp_hit-from>
      <Hsp_hit-to>422</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>193</Hsp_align-len>
      <Hsp_qseq>RNKYLCVQMYDWFDYHGHMCIAFELLGLSTFDFLKENNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYN---------PQKKRDERTVRNADIRVVDFGSAT----------------FDYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNRE</Hsp_qseq>
      <Hsp_hseq>RSEWLVKLLYAFQDLQS-LYLAMEFVPGGDFRTLLINTRCLKSGHARFYISEMFC-AVNALHDLGYTHRDLKPENFL-IDAKGHIKLTDFGLAAGTISNERIESMKIRLEKIKDLEFPAFTEKSIEDRRKMYNQLREKEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNE</Hsp_hseq>
      <Hsp_midline>R+++L   +Y + D    + +A E +    F  L  N       H    ++   C A+  LHD   TH DLKPEN L +D++  IK             ++ +   +R   I+ ++F + T                 +  + +++V +  Y A EVL    +    D WS+GC++FE  +G+T F      E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YPR111W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:747306:749000:1 gene:YPR111W transcript:YPR111W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF20 description:Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006315]</Hit_def>
  <Hit_accession>YPR111W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>2.29458e-06</Hsp_evalue>
      <Hsp_query-from>891</Hsp_query-from>
      <Hsp_query-to>1421</Hsp_query-to>
      <Hsp_hit-from>225</Hsp_hit-from>
      <Hsp_hit-to>426</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>205</Hsp_align-len>
      <Hsp_qseq>RNKYLCVQMYDWFDYHGHMCIAFELLGLSTFDFLKENNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYN---------PQKKRDERTVRNADIRVVDFGSAT----------------FDYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLF---QTHDNREHLAMMERTL</Hsp_qseq>
      <Hsp_hseq>RSDWLVKLLYAFQDPES-LYLAMEFVPGGDFRTLLINTRILKSGHARFYISEMFC-AVNALHELGYTHRDLKPENFL-IDATGHIKLTDFGLAAGTVSNERIESMKIRLEEVKNLEFPAFTERSIEDRRKIYHNMRKTEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYENLRYWKKTL</Hsp_hseq>
      <Hsp_midline>R+ +L   +Y + D    + +A E +    F  L  N  +    H    ++   C A+  LH+   TH DLKPEN L +D+   IK             ++ +   +R  +++ ++F + T                 +  + +++V +  Y A EVL    +    D WS+GC++FE  +G+T F    T++  E+L   ++TL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>2.54526e-06</Hsp_evalue>
      <Hsp_query-from>1047</Hsp_query-from>
      <Hsp_query-to>1352</Hsp_query-to>
      <Hsp_hit-from>129</Hsp_hit-from>
      <Hsp_hit-to>211</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>104</Hsp_align-len>
      <Hsp_qseq>QLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNAD--IRVVDFGSATFDYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEF</Hsp_qseq>
      <Hsp_hseq>QTLLGLKYLHGEGVIHRDIKAANILL---------------------SADNTVKLADFGVSTIVNSSALTLAGTLNWMAPEILGNRGASTLSDIWSLGATVVEM</Hsp_hseq>
      <Hsp_midline>Q    +K+LH   + H D+K  NIL                      +AD  +++ DFG +T       T+  T ++ APE+L   G S   D+WS+G  V E </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>2.83239e-06</Hsp_evalue>
      <Hsp_query-from>1014</Hsp_query-from>
      <Hsp_query-to>1364</Hsp_query-to>
      <Hsp_hit-from>439</Hsp_hit-from>
      <Hsp_hit-to>539</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>120</Hsp_align-len>
      <Hsp_qseq>YPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATF---DYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGF</Hsp_qseq>
      <Hsp_hseq>FSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILL---DY----------------QGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGL</Hsp_hseq>
      <Hsp_midline>+ L + R    +L  A+  LH   + + DLKPENIL    +Y                   I + DFG       D +   T   T  Y APE+LL  G+++  D W++G +++E   G </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>3.30007e-06</Hsp_evalue>
      <Hsp_query-from>1047</Hsp_query-from>
      <Hsp_query-to>1667</Hsp_query-to>
      <Hsp_hit-from>140</Hsp_hit-from>
      <Hsp_hit-to>287</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>71</Hsp_gaps>
      <Hsp_align-len>213</Hsp_align-len>
      <Hsp_qseq>QLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHHS-----TIVSTRHYRAPEVLLELGWSQ-PCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENCKPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPFF</Hsp_qseq>
      <Hsp_hseq>QISGAVYYAHSMHCVHRDLKLENILL-------------------DKNGNAKLTDFG---FTRECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFD-------------------------------------DDDEAKTKWKIVNEEPK-YDAKVIPDDAR-----DLISRLLAKNPGERPSLSQVLRHPFL</Hsp_hseq>
      <Hsp_midline>Q+  A+ + H     H DLK ENIL                     +N + ++ DFG   F  E  +     T+  T  Y APE++    +     D+WS+G I++    G+  F                                      D DE+ +  K V E  K     V+ DDA+     DLI ++L   P +R +L + L+HPF </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YDL025C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:405344:407206:-1 gene:YDL025C transcript:YDL025C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RTK1 description:Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002183]</Hit_def>
  <Hit_accession>YDL025C</Hit_accession>
  <Hit_len>620</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>6.92044e-06</Hsp_evalue>
      <Hsp_query-from>1047</Hsp_query-from>
      <Hsp_query-to>1358</Hsp_query-to>
      <Hsp_hit-from>413</Hsp_hit-from>
      <Hsp_hit-to>505</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>112</Hsp_align-len>
      <Hsp_qseq>QLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSA-TFDYEHHSTIVSTRH------YRAPEVLLELGW-SQPCDVWSIGCIVFEFYL</Hsp_qseq>
      <Hsp_hseq>QLCHGVNYLHSMGLAHRDLKLDNCVV-------------------TKDGILKLIDFGSAVVFQYPYEDTIVKSHGIVGSDPYLAPELLKQTSYDPRVADVWSIAIIFYCMVL</Hsp_hseq>
      <Hsp_midline>QLC+ + +LH   L H DLK +N +                     ++  ++++DFGSA  F Y +  TIV +        Y APE+L +  +  +  DVWSI  I +   L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>7.48088e-06</Hsp_evalue>
      <Hsp_query-from>1029</Hsp_query-from>
      <Hsp_query-to>1535</Hsp_query-to>
      <Hsp_hit-from>1367</Hsp_hit-from>
      <Hsp_hit-to>1538</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>188</Hsp_align-len>
      <Hsp_qseq>VRLMAYQLCYAIKFLHDNKLTHTDLKPENIL--------FVD--SEYDIKYNPQKKRDERTVRNAD------IRVVDFGSATFDYEHHSTIVSTRHYRAPEVL---LELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENC</Hsp_qseq>
      <Hsp_hseq>TQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPWANLDN-EWAIMYHVAAGHTPQFPTK---------------DEVSSAGMKFLERC</Hsp_hseq>
      <Hsp_midline> ++   QL   + +LH++ + H D+KPENIL        +VD  +   I  N  +      + NAD        V D  +   +      ++ T  Y APE +      G     DVWS+GC+V E   G   +   DN E   M     G  P    +               DE SSAG    E C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2559864913</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052665-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.72 eAED:0.74 QI:0|0|0.25|0.5|1|1|4|0|515</Iteration_query-def>
  <Iteration_query-len>1548</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>967927474</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0029813-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.2|0.36|11|122|670</Iteration_query-def>
  <Iteration_query-len>2135</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1396154338</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052653-RA transcript Note:&quot;Similar to fech Ferrochelatase, mitochondrial (Xenopus laevis)&quot; offset:0 AED:0.14 eAED:0.14 QI:0|0.63|0.5|0.83|1|1|12|1732|395</Iteration_query-def>
  <Iteration_query-len>2920</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YOR176W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:662401:663582:1 gene:YOR176W transcript:YOR176W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HEM15 description:Ferrochelatase; a mitochondrial inner membrane protein, catalyzes insertion of ferrous iron into protoporphyrin IX, the eighth and final step in the heme biosynthetic pathway; human homolog FECH can complement yeast mutant and allow growth of haploid null after sporulation of a heterozygous diploid [Source:SGD;Acc:S000005702]</Hit_def>
  <Hit_accession>YOR176W</Hit_accession>
  <Hit_len>393</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>314.309</Hsp_bit-score>
      <Hsp_score>804</Hsp_score>
      <Hsp_evalue>9.05928e-99</Hsp_evalue>
      <Hsp_query-from>169</Hsp_query-from>
      <Hsp_query-to>1131</Hsp_query-to>
      <Hsp_hit-from>39</Hsp_hit-from>
      <Hsp_hit-to>373</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>173</Hsp_identity>
      <Hsp_positive>228</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>342</Hsp_align-len>
      <Hsp_qseq>TGILLLNMGGPETTDDVHXXXXXXXXXXXXIPLPA--QSKLAPWIAKRRTPKIQEQYSRIGGGSPIKLKTTSRGSEGDELRCRDRT-------------GATEPLTEDTIEEMERDGIQRAVAFTQYPQFSCSTTGSSLNAIYRHYEQRGTPPRMAWSVIDRWPTHPGLVKCFSDHIKKELQEFPADVRGDVVILFSAHSLPMSVVNRGDPYPQEVAATVQRVMEQLNFSHPYRLVWQSKVGPMPWLGPQTDATIKGLAERGKRHMLLVPIAFTTDHIETLHELDI------EYAQCGVENIRRAESLNANPVFIEAMADLVKVHLESGSTCSRQLGLRCPL</Hsp_qseq>
      <Hsp_hseq>TGIVLMNMGGPSKVEETYDFLYQLFADNDLIPISAKYQKTIAKYIAKFRTPKIEKQYREIGGGSPIRKWSEYQATE--VCKILDKTCPETAPHKPYVAFRYAKPLTAETYKQMLKDGVKKAVAFSQYPHFSYSTTGSSINELWRQIKALDSERSISWSVIDRWPTNEGLIKAFSENITKKLQEFPQPVRDKVVLLFSAHSLPMDVVNTGDAYPAEVAATVYNIMQKLKFKNPYRLVWQSQVGPKPWLGAQTAEIAEFLGPKVD-GLMFIPIAFTSDHIETLHEIDLGVIGESEYK----DKFKRCESLNGNQTFIEGMADLVKSHLQSNQLYSNQLPLDFAL</Hsp_hseq>
      <Hsp_midline>TGI+L+NMGGP   ++ +DFL +LF D DLIP+ A  Q  +A +IAK RTPKI++QY  IGGGSPI+  +  + +E    +  D+T                +PLT +T ++M +DG+++AVAF+QYP FS STTGSS+N ++R  +   +   ++WSVIDRWPT+ GL+K FS++I K+LQEFP  VR  VV+LFSAHSLPM VVN GD YP EVAATV  +M++L F +PYRLVWQS+VGP PWLG QT    + L  +    ++ +PIAFT+DHIETLHE+D+      EY     +  +R ESLN N  FIE MADLVK HL+S    S QL L   L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>1975822958</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052654-RA transcript Note:&quot;Similar to PIGO GPI ethanolamine phosphate transferase 3 (Homo sapiens)&quot; offset:0 AED:0.32 eAED:0.32 QI:0|0.14|0|0.87|1|1|8|0|974</Iteration_query-def>
  <Iteration_query-len>2925</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YLL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:77152:80205:-1 gene:YLL031C transcript:YLL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GPI13 description:ER membrane localized phosphoryltransferase; adds phosphoethanolamine onto the third mannose residue of the glycosylphosphatidylinositol (GPI) anchor precursor; similar to human PIG-O protein [Source:SGD;Acc:S000003954]</Hit_def>
  <Hit_accession>YLL031C</Hit_accession>
  <Hit_len>1017</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>149.443</Hsp_bit-score>
      <Hsp_score>376</Hsp_score>
      <Hsp_evalue>3.28092e-37</Hsp_evalue>
      <Hsp_query-from>70</Hsp_query-from>
      <Hsp_query-to>732</Hsp_query-to>
      <Hsp_hit-from>53</Hsp_hit-from>
      <Hsp_hit-to>318</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>98</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>85</Hsp_gaps>
      <Hsp_align-len>286</Hsp_align-len>
      <Hsp_qseq>FTRGFLLNRSEIVRNSSCADFXXXXXXXXXXXXXXXNRSCWAVPARYRRAVLVVIDALRLDFA--TYDAARSEPKPYENRLPALHAALQATPRHAR--LFRFRADPPTTTMQRLKALATGGLPTFIDVSSNFASARVEEDNLVGQL------VSVVAKSDW--------------------------------------------DVIIAHFLGVDHVGHRLGPLHPAMSDK-----------LSQMNEDAVLLVMGDHGMTETGDHGGESERETSAALFVYSPIP</Hsp_qseq>
      <Hsp_hseq>FTRGFLLSRHVLDNISS------------------QNETS-KLPPRFNKAVILVIDALRFDFAIPVNESHSNYNLNYHNNILSLYDSF-ASDKDASSLLLKFIADPPTTTLQRLKGLTTGSLPTFIDAGSNFDGTVIEEDNFLKQLHLANKTVKFAGDDTWMALFHPFLSNDSFPLESLNVWDLDTVDNGVMDYFHDHLQQDKEWDVMIGHMLGIDHVGHKYGPDHFTMREKQIQVDQFIDWILKSIDDDTLLVILGDHGMDHTGNHGGDSIDELESTLFLYSKKP</Hsp_hseq>
      <Hsp_midline>FTRGFLL+R  +   SS                   N +   +P R+ +AV++VIDALR DFA    ++  +    Y N + +L+ +  A+ + A   L +F ADPPTTT+QRLK L TG LPTFID  SNF    +EEDN + QL      V       W                                            DV+I H LG+DHVGH+ GP H  M +K           L  +++D +L+++GDHGM  TG+HGG+S  E  + LF+YS  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YJL062W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:317284:319776:1 gene:YJL062W transcript:YJL062W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:LAS21 description:Integral plasma membrane protein; involved in the synthesis of the glycosylphosphatidylinositol (GPI) core structure; mutations affect cell wall integrity [Source:SGD;Acc:S000003598]</Hit_def>
  <Hit_accession>YJL062W</Hit_accession>
  <Hit_len>830</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>92.4337</Hsp_bit-score>
      <Hsp_score>228</Hsp_score>
      <Hsp_evalue>1.29154e-19</Hsp_evalue>
      <Hsp_query-from>208</Hsp_query-from>
      <Hsp_query-to>726</Hsp_query-to>
      <Hsp_hit-from>51</Hsp_hit-from>
      <Hsp_hit-to>285</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>86</Hsp_gaps>
      <Hsp_align-len>247</Hsp_align-len>
      <Hsp_qseq>YRRAVLVVIDALRLDFATYDAARSEPKPYENRLPALHAALQATPRHARLFRFRADPPTTTMQRLKALATGGLPTFID--------VSSN---------------------------------------------FASARVEEDN-----LVGQLVSVVAKSDWDVIIAHFLGVDHVGHRLGPLHPAMSDKLSQMN----------------EDAVLLVMGDHGMTETGDHGGESERETSAALFVYSP</Hsp_qseq>
      <Hsp_hseq>FQKLVFVIIDALRSDFL-FDSQISH---FNN----VHQWLNT--GEAWGYTSFANPPTVTLPRLKSITTGSTPSFIDLLLNVAQDIDSNDLSEHDSWLQQFIQHNNTIRFMGDDTWLKLFPQQWFDFADPTHSFFVSDFTQVDNNVTRNLPGKLFQEWAQ--WDVAILHYLGLDHIGHKDGPHSKFMAAKHQEMDSILKSIYDEVLEHEDDDDTLICVLGDHGMNELGNHGGSSAGETSAGLLFLSP</Hsp_hseq>
      <Hsp_midline>+++ V V+IDALR DF  +D+  S    + N    +H  L      A  +   A+PPT T+ RLK++ TG  P+FID        + SN                                             F S   + DN     L G+L    A+  WDV I H+LG+DH+GH+ GP    M+ K  +M+                +D ++ V+GDHGM E G+HGG S  ETSA L   SP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>1980344292</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052657-RA transcript Note:&quot;Similar to MAPK6 Mitogen-activated protein kinase 6 (Homo sapiens)&quot; offset:1061 AED:0.05 eAED:0.05 QI:1061|0.83|0.85|1|0.83|0.71|7|2027|1047</Iteration_query-def>
  <Iteration_query-len>6232</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>170.244</Hsp_bit-score>
      <Hsp_score>430</Hsp_score>
      <Hsp_evalue>2.77514e-45</Hsp_evalue>
      <Hsp_query-from>1101</Hsp_query-from>
      <Hsp_query-to>1976</Hsp_query-to>
      <Hsp_hit-from>17</Hsp_hit-from>
      <Hsp_hit-to>339</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>110</Hsp_identity>
      <Hsp_positive>171</Hsp_positive>
      <Hsp_gaps>63</Hsp_gaps>
      <Hsp_align-len>339</Hsp_align-len>
      <Hsp_qseq>FELGPRYVDLKPLGFGGNGLVFSA--VDSDCDKRVAIKKL--VLSGPHSLKHALREIKIIRRL-DHDNIVRVFE---VLGPAGQRLPLGQAGIGTSALAELECVYIVQDYLETDLARVLEQGSALSEEHARLFMYQLLRGLKYIHSAN----------------------------GY----------LSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLSGKTLFAGAHELEQMQLILQTIPVMRDEDHQEL-LNVIPVFVDKERREPPKPLALLLPNVSKEALDFLQQILTFNPMDRLTAEQALAHPYMSLYAFPQDEPVARQPFHIEDE</Hsp_qseq>
      <Hsp_hseq>FSVDKRFQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDG----------------SINGLYLYEELMECDMHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPYLSIWHDPADEPVCSEKFEFSFE</Hsp_hseq>
      <Hsp_midline>F +  R+  +K +G G  G+V SA   ++  D  VAIKK+  V S     K +LRE+K++R    H NI  +++   V  P G                 +  +Y+ ++ +E D+ ++++ G  L++ H + F YQ+L GLKYIHSA+                            GY          L+E + T+WYR+P ++LS   YTKAID+W+AGCI AE L GK +F G   + Q+  ILQ +    DE  + +    +  ++ +    P  P   L PN + +ALD L+Q+L F+P  R+T ++AL HPY+S++  P DEPV  + F    E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>165.236</Hsp_bit-score>
      <Hsp_score>417</Hsp_score>
      <Hsp_evalue>5.60906e-44</Hsp_evalue>
      <Hsp_query-from>1101</Hsp_query-from>
      <Hsp_query-to>1973</Hsp_query-to>
      <Hsp_hit-from>17</Hsp_hit-from>
      <Hsp_hit-to>324</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>110</Hsp_identity>
      <Hsp_positive>163</Hsp_positive>
      <Hsp_gaps>71</Hsp_gaps>
      <Hsp_align-len>335</Hsp_align-len>
      <Hsp_qseq>FELGPRYVDLKPLGFGGNGLVFSAVDSDCDKRVAIKKLV--LSGPHSLKHALREIKIIRRLDHDNIVRVFEVLGPAGQRLPLGQAGIGTSALAELECVYIVQDYLETDLARVLEQGSALSEEHARLFMYQLLRGLKYIHSA-----------------------------------NGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLSGKTLFAGAHELEQMQLILQTIPVMRDEDHQELLNVIPV-----FVDKERREPPKPLALLLPNVSKEALDFLQQILTFNPMDRLTAEQALAHPYMSLYAFPQDEPVARQPF--HIED</Hsp_qseq>
      <Hsp_hseq>FEITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIF------------------LSPLEDIYFVTELQGTDLHRLL-QTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVS----TRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITD----LLGSPPKDVINTICSENTLKFVTSLPHRDPIPFSERFKTVEPDAVDLLEKMLVFDPKKRITAADALAHPYSAPYHDPTDEPVADAKFDWHFND</Hsp_hseq>
      <Hsp_midline>FE+  RY DL P+G G  GLV SA D+   + VAIKK++   S     K   RE+K+++ L H+N++ + ++                   L+ LE +Y V +   TDL R+L Q   L ++  + F+YQ+LRGLKY+HSA                                    GY+S    T++YR+P ++L+   Y   +D+W+AGCIFAEM+ GK LF G   + Q  +I      +     ++++N I       FV       P P +     V  +A+D L+++L F+P  R+TA  ALAHPY + Y  P DEPVA   F  H  D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>156.762</Hsp_bit-score>
      <Hsp_score>395</Hsp_score>
      <Hsp_evalue>8.60734e-42</Hsp_evalue>
      <Hsp_query-from>1101</Hsp_query-from>
      <Hsp_query-to>1976</Hsp_query-to>
      <Hsp_hit-from>7</Hsp_hit-from>
      <Hsp_hit-to>333</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>102</Hsp_identity>
      <Hsp_positive>171</Hsp_positive>
      <Hsp_gaps>65</Hsp_gaps>
      <Hsp_align-len>342</Hsp_align-len>
      <Hsp_qseq>FELGPRYVDLKPLGFGGNGLVFSAVDSDCDKRVAIKKL-VLSGPHSLKHALREIKIIRRL-DHDNIVRVFEVLGPAGQRLPLGQAGIGTSALAELECVYIVQDYLETDLARVLEQG----SALSEEHARLFMYQLLRGLKYIHSAN-----------------------------------------GYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLSGKTLFAGAHELEQMQLILQTIPVMRDEDHQELLNV-IPVFVDKERREPPKPLALLL--PNVSKEALDFLQQILTFNPMDRLTAEQALAHPYMSLYAFPQDEPVARQPFHIEDE</Hsp_qseq>
      <Hsp_hseq>FDIPSQYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPV--------------SIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIANLPMRPPLPWETVWSKTDLNPDMIDLLDKMLQFNPDKRISAAEALRHPYLAMYHDPSDEP-EYPPLNLDDE</Hsp_hseq>
      <Hsp_midline>F++  +Y  +  +G G  G V SA+      +VAIKK+   S    +   +REIK++R   +H+NI+ + + + P               ++ +L  VY+V++ +ETDL +V+       S LS++H + F YQ+LR LK IHSA                                          G+++E + T+WYR+P ++L+   YT A+D+W+ GCI AEM+SGK LF G     Q+ LIL+ +     ED  ++ +     ++      PP P   +    +++ + +D L ++L FNP  R++A +AL HPY+++Y  P DEP    P +++DE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>147.132</Hsp_bit-score>
      <Hsp_score>370</Hsp_score>
      <Hsp_evalue>1.37392e-38</Hsp_evalue>
      <Hsp_query-from>1137</Hsp_query-from>
      <Hsp_query-to>1943</Hsp_query-to>
      <Hsp_hit-from>19</Hsp_hit-from>
      <Hsp_hit-to>319</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>92</Hsp_identity>
      <Hsp_positive>149</Hsp_positive>
      <Hsp_gaps>76</Hsp_gaps>
      <Hsp_align-len>323</Hsp_align-len>
      <Hsp_qseq>LGFGGNGLVFSAVDSDCDKRVAIKKL-VLSGPHSLKHALREIKIIRRLDHDNIVRVFEVLGPAGQRLPLGQAGIGTSALAELECVYIVQDYLETDLARVLEQGSALSEEHARLFMYQLLRGLKYIHSANGY--------------------------------------------LSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLSGKTLFAGAHELEQMQLILQTIPVMRDEDH---------QELLNVIPVFVDKERREPPKPLALLLPNVSKEALDFLQQILTFNPMDRLTAEQALAHPYMSLYAFPQDEP</Hsp_qseq>
      <Hsp_hseq>LGEGAYGVVCSATHKPTGEIVAIKKIEPFDKPLFALRTLREIKILKHFKHENIITIFNIQRP--------------DSFENFNEVYIIQELMQTDLHRVI-STQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHSDNDLRCIESPRAREYIKSLPMY-------PAAPLEKMFPRVNPKGIDLLQRMLVFDPAKRITAKEALEHPYLQTYHDPNDEP</Hsp_hseq>
      <Hsp_midline>LG G  G+V SA      + VAIKK+     P      LREIKI++   H+NI+ +F +  P               +      VYI+Q+ ++TDL RV+     LS++H + F+YQ LR +K +H +N                                              ++E + T+WYR+P ++L+   Y++A+D+W+ GCI AE+   + +F G     Q+ LI   I     ++          +E +  +P++       P  PL  + P V+ + +D LQ++L F+P  R+TA++AL HPY+  Y  P DEP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>136.732</Hsp_bit-score>
      <Hsp_score>343</Hsp_score>
      <Hsp_evalue>1.94787e-34</Hsp_evalue>
      <Hsp_query-from>1137</Hsp_query-from>
      <Hsp_query-to>1976</Hsp_query-to>
      <Hsp_hit-from>29</Hsp_hit-from>
      <Hsp_hit-to>339</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>94</Hsp_identity>
      <Hsp_positive>159</Hsp_positive>
      <Hsp_gaps>63</Hsp_gaps>
      <Hsp_align-len>327</Hsp_align-len>
      <Hsp_qseq>LGFGGNGLVFSAV--DSDCDKRVAIKKL--VLSGPHSLKHALREIKIIRRL-DHDNIVRVFE---VLGPAGQRLPLGQAGIGTSALAELECVYIVQDYLETDLARVLEQGSALSEEHARLFMYQLLRGLKYIHSAN--------------------------------------GYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLSGKTLFAGAHELEQMQLILQTIPVMRDEDHQELLN-VIPVFVDKERREPPKPLALLLPNVSKEALDFLQQILTFNPMDRLTAEQALAHPYMSLYAFPQDEPVARQPFHIEDE</Hsp_qseq>
      <Hsp_hseq>IGRGSHSLICSSTYTESNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGA----------------LNGVYLYEELMECDLSQIIRSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIPGRSFESILPGANPEALELLKKMLEFDPKKRITVEDALEHPYLSMWHDIDEEFSCQKTFRFEFE</Hsp_hseq>
      <Hsp_midline>+G G + L+ S+   +S+ +  VAI+K+        S K  LRE+K++R L  H NIV +F+   V  P G                 L  VY+ ++ +E DL++++     L + H + F+YQ+L  LKYIHSAN                                      G++   + + WY++P +LL+    TKA+D+W+ GCI AE+L  K +F G   ++ +  ILQ +    +E  QE+ +  +  ++ +    P +    +LP  + EAL+ L+++L F+P  R+T E AL HPY+S++    +E   ++ F  E E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>126.716</Hsp_bit-score>
      <Hsp_score>317</Hsp_score>
      <Hsp_evalue>2.48971e-31</Hsp_evalue>
      <Hsp_query-from>1194</Hsp_query-from>
      <Hsp_query-to>1976</Hsp_query-to>
      <Hsp_hit-from>65</Hsp_hit-from>
      <Hsp_hit-to>359</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>93</Hsp_identity>
      <Hsp_positive>147</Hsp_positive>
      <Hsp_gaps>70</Hsp_gaps>
      <Hsp_align-len>313</Hsp_align-len>
      <Hsp_qseq>RVAIKKL--VLSGPHSLKHALREIKIIRRLD-HDNIVRVFEVLGPAGQRLPLGQAGIGTSALAELECVYIVQDYLETDLARVLEQGSALSEEHARLFMYQLLRGLKYIHSA----------------NG--------------------------YLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLSGKTLFAGAHELEQMQLILQTIPVMRDEDHQELLNVIPV---FVDKERREP---PKPLALLLPNVSKEALDFLQQILTFNPMDRLTAEQALAHPYMSLYAFPQDEPVARQ-PFHIEDE</Hsp_qseq>
      <Hsp_hseq>RIAVKKISNIFNKEILLKRAIRELKFMNFFKGHKNIVNLIDL-------------EIVTSS--PYDGLYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQ---IFEIIKVLGTPDKDILIKFGTIKAWNLGKNSNNPVYKKIPWSNIFPFASHEAINLIESLLHWDSTHRLNVEQAISHPFLNEVRKPDDEPVCLQGPFDFTYE</Hsp_hseq>
      <Hsp_midline>R+A+KK+  + +    LK A+RE+K +     H NIV + ++              I TS+    + +Y  Q+ ++ DLA+V+     LSE H + F+YQ+L GLKYIHSA                NG                          +++  + T+WYR+P LLLS   Y+K++D+WA GCI AE  + K +F G   + Q   I + I V+   D   L+    +    + K    P     P + + P  S EA++ ++ +L ++   RL  EQA++HP+++    P DEPV  Q PF    E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>117.857</Hsp_bit-score>
      <Hsp_score>294</Hsp_score>
      <Hsp_evalue>5.16327e-29</Hsp_evalue>
      <Hsp_query-from>1116</Hsp_query-from>
      <Hsp_query-to>1922</Hsp_query-to>
      <Hsp_hit-from>6</Hsp_hit-from>
      <Hsp_hit-to>300</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>85</Hsp_identity>
      <Hsp_positive>149</Hsp_positive>
      <Hsp_gaps>68</Hsp_gaps>
      <Hsp_align-len>316</Hsp_align-len>
      <Hsp_qseq>RYVDLKPLGFGGNGLVFSAVDSDCDKRVAIKKLVL-SGPHSLKHALREIKIIRRLDHDNIVRVFEVLGPAGQRLPLGQAGIGTSALAELECVYIVQDYLETDLARVLEQGS------ALSEEHARLFMYQLLRGLKYIHS-----------------------------------ANGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLSGKTLFAGAHELEQMQLILQTIPVMRDEDHQELLNVIPVFVDKERREPPKPLALLLPNVSKEAL-----DFLQQILTFNPMDRLTAEQALAHPYMSLY</Hsp_qseq>
      <Hsp_hseq>QFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENK-------------------LTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSE-VVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGT-PNESLWPSVTKLPKYNPNIQQRPPRDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWFAEY</Hsp_hseq>
      <Hsp_midline>++  L+ LG G    V+  ++      VA+K++ L S   +   A+REI +++ L H+NIVR+++V+    +                   + +V ++++ DL + ++  +       L     + F +QLL+GL + H                                     N + SE +VT WYR+P +L+    Y+ +ID+W+ GCI AEM++GK LF G ++ EQ++LI   +    +E     +  +P +    ++ PP+ L  +L   +KE L     DFL  +L  NP  RL+A+QAL HP+ + Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>117.087</Hsp_bit-score>
      <Hsp_score>292</Hsp_score>
      <Hsp_evalue>7.96536e-29</Hsp_evalue>
      <Hsp_query-from>1119</Hsp_query-from>
      <Hsp_query-to>1913</Hsp_query-to>
      <Hsp_hit-from>8</Hsp_hit-from>
      <Hsp_hit-to>295</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>84</Hsp_identity>
      <Hsp_positive>146</Hsp_positive>
      <Hsp_gaps>67</Hsp_gaps>
      <Hsp_align-len>310</Hsp_align-len>
      <Hsp_qseq>YVDLKPLGFGGNGLVFSAVD---SDCDKRVAIKKLVLSGPHS--LKHALREIKIIRRLDHDNIVRVFEVLGPAGQRLPLGQAGIGTSALAELECVYIVQDYLETDLARVLE---QGSALSEEHARLFMYQLLRGLKYIHS----------------ANGYLSEG------------------LVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLSGKTLFAGAHELEQMQLILQTIPVMRDE---DHQELLNVIPVFVDKERREPPKPLALLLPNVSKEALDFLQQILTFNPMDRLTAEQALAHPYM</Hsp_qseq>
      <Hsp_hseq>YKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKL------------------YLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIVYLPDFKPSFPQWRRKD----LSQVVPSLDPRGIDLLDKLLAYDPINRISARRAAIHPYF</Hsp_hseq>
      <Hsp_midline>Y  L+ +G G  G+V+ A+D       + VA+KK+ L          A+REI +++ L  DNIVR+++++     +L                  Y+V ++L+ DL R +E   +   L  +  + FM QL +G+ Y HS                 +G L  G                  +VT WYR+P +LL    Y+  +D W+ GCIFAEM + K +F+G  E++Q+  I + +    +    D   L +  P F    R++    L+ ++P++    +D L ++L ++P++R++A +A  HPY </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>112.849</Hsp_bit-score>
      <Hsp_score>281</Hsp_score>
      <Hsp_evalue>1.50727e-25</Hsp_evalue>
      <Hsp_query-from>1119</Hsp_query-from>
      <Hsp_query-to>2156</Hsp_query-to>
      <Hsp_hit-from>60</Hsp_hit-from>
      <Hsp_hit-to>442</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>104</Hsp_identity>
      <Hsp_positive>164</Hsp_positive>
      <Hsp_gaps>63</Hsp_gaps>
      <Hsp_align-len>396</Hsp_align-len>
      <Hsp_qseq>YVDLKPLGFGGNGLVFSAVDSDCDKRVAIKKLVLSGPHSL--KHALREIKIIRRLDHDNIVRVFEVLGPAGQRLPLGQAGIGTSALAEL-ECVYIVQDYLETDLARVLEQGSA-LSEEHARLFMYQLLRGLKYIHSA----------------NGYL------------------------------SEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLSGKTLFAGAHELEQMQLILQTIPVMRDEDHQELLNVIPVFVDKERREPPKPLALLLPNVSKEALDFLQQILTFNPMDRLTAEQALAHPYMSLYAFPQDEPVARQPFHIEDEIDDALLTDESHSQQAQWSRYPDSTDTDWYSHGELDVAQKDPRAMASSSSEEDGVQLDPRK</Hsp_qseq>
      <Hsp_hseq>YREDEKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHS-------PDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTEED-WAVARYLPGAELTTTNYKPTLRERFGKYLSETGLDFLGQLLALDPYKRLTAMSAKHHPWFKEDPLPSEK--ITLPTEESHEADIKRYKEEMHQSLSQ--RVPTAPRGHIVEKGESPVV-KNLGAIPRGPKKDDASFLPPSK</Hsp_hseq>
      <Hsp_midline>Y + + LG G  G V+  +  +  ++VA+KK+++S    L    A REI I++RL+H NI+++ E++             I  +A + L +  Y++  Y+  DL+ VL      L     +  M Q+L GL YIH A                NG L                              +  +VT+WYR+P L+L    YT A+D+W  GC+FAE    K +  G  +++Q  +I + +    +ED   +   +P          P         +S+  LDFL Q+L  +P  RLTA  A  HP+      P ++     P     E D     +E H   +Q  R P +        GE  V  K+  A+     ++D   L P K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>99.3673</Hsp_bit-score>
      <Hsp_score>246</Hsp_score>
      <Hsp_evalue>2.50361e-22</Hsp_evalue>
      <Hsp_query-from>1137</Hsp_query-from>
      <Hsp_query-to>1913</Hsp_query-to>
      <Hsp_hit-from>45</Hsp_hit-from>
      <Hsp_hit-to>322</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>53</Hsp_gaps>
      <Hsp_align-len>295</Hsp_align-len>
      <Hsp_qseq>LGFGGNGLVFSAVDSDCDKRVAIKKLVLSGPHSLKHALREIKIIRRLDHDNIVRVFEVLGPAGQRLPLGQAGIGTSALAELECVYIVQDYLETDLARVLEQGSALSEEHARLFMYQLLRGLKYIHSANGYLSEGL-----------------------------------VTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLSGKTLFAGAHELEQMQLILQTIPVMRDEDHQELLNVIPVFVD-KERREPPKPLALLLPNVSKEALDFLQQILTFNPMDRLTAEQALAHPYM</Hsp_qseq>
      <Hsp_hseq>VGHGSFGVVFATVIQETNEKVAIKKVL----QDKRFKNRELEIMKMLSHINIIDLKYFFYERD-----SQDEIYLNLILE----YMPQS-LYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQL---VEIIKILGTPSKQEICSMNPNYMEHKFPQIKPIPLSRVFKKEDDQTVEFLADVLKYDPLERFNALQCLCSPYF</Hsp_hseq>
      <Hsp_midline>+G G  G+VF+ V  + +++VAIKK++       +   RE++I++ L H NI+ +              Q  I  + + E    Y+ Q  L   L   + Q + +S    + +M+QL + L Y+H         +                                    +++YR+P L+    NYT  ID+W++GC+ AE+L G+ +F G   ++Q+   ++ I ++     QE+ ++ P +++ K  +  P PL+ +      + ++FL  +L ++P++R  A Q L  PY </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>98.5969</Hsp_bit-score>
      <Hsp_score>244</Hsp_score>
      <Hsp_evalue>2.0897e-21</Hsp_evalue>
      <Hsp_query-from>1119</Hsp_query-from>
      <Hsp_query-to>1949</Hsp_query-to>
      <Hsp_hit-from>183</Hsp_hit-from>
      <Hsp_hit-to>479</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>136</Hsp_positive>
      <Hsp_gaps>64</Hsp_gaps>
      <Hsp_align-len>319</Hsp_align-len>
      <Hsp_qseq>YVDLKPLGFGGNGLVFSAVDSDCDKRVAIKKLVLSGPHS--LKHALREIKIIRRLDHDNIVRVFEVLGPAGQRLPLGQAGIGTSALAELECVYIVQDYLETDLARVL-EQGSALSEEHARLFMYQLLRGLKYIH---------------------------------SANGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLSGKTLFAGAHELEQMQLILQTI--PVMRD----EDHQELLNVIPVFVDKERREPPKPLALLLPNVSKEALDFLQQILTFNPMDRLTAEQALAHPYMSLYAFPQDEPVA</Hsp_qseq>
      <Hsp_hseq>YLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNVSTIKEIM------------------VESQKTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKMNSRADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTPTINSWPTLYDMPWFFMIMPQQTTKYVNNFSEKFKSVLP--SSKCLQLAINLLCYDQTKRFSATEALQSDYFK--EEPKPEPLV</Hsp_hseq>
      <Hsp_midline>Y+ +  +G G  G V+ A +++ +K VA+KKL L G        ++REIK+++  DH N+  + E++                  +   + VY++ +Y + DL+ +L  +   +S    +    QLL G++Y+H                                 ++    +  ++T WYR P LLL   NY   +DMW  GC+  E+ +   +F G++ELEQ++ I + +  P +       D      ++P    K      +    +LP  S + L     +L ++   R +A +AL   Y      P+ EP+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.5077</Hsp_bit-score>
      <Hsp_score>223</Hsp_score>
      <Hsp_evalue>7.97646e-20</Hsp_evalue>
      <Hsp_query-from>1119</Hsp_query-from>
      <Hsp_query-to>1937</Hsp_query-to>
      <Hsp_hit-from>7</Hsp_hit-from>
      <Hsp_hit-to>298</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>132</Hsp_positive>
      <Hsp_gaps>65</Hsp_gaps>
      <Hsp_align-len>315</Hsp_align-len>
      <Hsp_qseq>YVDLKPLGFGGNGLVFSAVDSDCDKRVAIKKLVLSGPHS--LKHALREIKIIRRLDHDNIVRVFEVLGPAGQRLPLGQAGIGTSALAELECVYIVQDYLETDLARVLEQGSAL-SEEHARLFMYQLLRGLKYIH----------------SANG------------------YLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLSGKTLFAGAHELEQMQLILQTIPVMRDEDHQEL-----LNVIPVFVDKERREPPKPLALLLPNVSKEALDFLQQILTFNPMDRLTAEQALAHPYMSLYAFPQD</Hsp_qseq>
      <Hsp_hseq>YTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNVIELIDIF-------------------MAYDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDRDWPEVSSFMTYNKLQIYPPPSRDELRKRFI----AASEYALDFMCGMLTMNPQKRWTAVQCLESDYFKELPPPSD</Hsp_hseq>
      <Hsp_midline>Y   K +G G   +V+        +++AIK++  S         A+RE+K ++ + H N++ + ++                       + + +V ++L TDL  V++  S L +    + +M   LRG+ + H                S +G                   L+  +VT+WYR+P LL    +YT AID+W+ G IFAE++       G ++++QM++  + +    D D  E+      N + ++    R E  K         S+ ALDF+  +LT NP  R TA Q L   Y      P D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.9593</Hsp_bit-score>
      <Hsp_score>206</Hsp_score>
      <Hsp_evalue>3.52802e-17</Hsp_evalue>
      <Hsp_query-from>1224</Hsp_query-from>
      <Hsp_query-to>1973</Hsp_query-to>
      <Hsp_hit-from>69</Hsp_hit-from>
      <Hsp_hit-to>351</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>128</Hsp_positive>
      <Hsp_gaps>65</Hsp_gaps>
      <Hsp_align-len>299</Hsp_align-len>
      <Hsp_qseq>GPHSLKHALR-------EIKIIRRLDHDNIVRVFEVLGPAGQRLPLGQAGIGTSALAELECVYIVQDYLETDLARVLEQGSALSEEHARLFMYQLLRGLKYIHSA----------------------------------NGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLSGKTLFAG---AHELEQMQLILQTIPVMRDEDHQELLNVIPVFVDKERREPPKPLALLLPNVSKEALDFLQQILTFNPMDRLTAEQALAHPYMS-----LYAFPQDEPVARQPFHIED</Hsp_qseq>
      <Hsp_hseq>GPYAIKRVVKSPKVQSLELEILQNIRHPNLVTL-EFFFESHCTTKDGGHLYQKNFVME----YIPQT-LSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGIAKVCDFGSAQRLDDNTELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPLFKGDSANSQLEEIAKLLGRFPKSSIKNSQEL-------QDSLNDQKFKKFMHWFPSIEFFDVEFLLKVLTYDATERCDARQLMAHEFFDALRNETYFLPRG---SSMPVHLPD</Hsp_hseq>
      <Hsp_midline>GP+++K  ++       E++I++ + H N+V + E    +      G      + + E    YI Q  L +++    + GS +  +H +L+ +Q+LR L  +HS                                   N  L     +++YR+P LLL+  +YT  ID+W+ GCI  EM+ G+ LF G     +LE++  +L   P    ++ QEL        D    +  K      P++    ++FL ++LT++  +R  A Q +AH +        Y  P+    +  P H+ D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.0333</Hsp_bit-score>
      <Hsp_score>201</Hsp_score>
      <Hsp_evalue>1.32539e-16</Hsp_evalue>
      <Hsp_query-from>1125</Hsp_query-from>
      <Hsp_query-to>1916</Hsp_query-to>
      <Hsp_hit-from>37</Hsp_hit-from>
      <Hsp_hit-to>328</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>132</Hsp_positive>
      <Hsp_gaps>68</Hsp_gaps>
      <Hsp_align-len>312</Hsp_align-len>
      <Hsp_qseq>DLKPLGFGGNGLVFSAVDSDCDKR----VAIKKLVLSGPHSLKHALREIKIIRRLDHDNIVRV---FEVLGPAGQRLPLGQAGIGTSALAELECVYIVQDYLETDLARVLEQGSALSEEHARLFMYQLLRGLKYIHS-----------------ANGYLS-----------------EGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLSGKTLFAGAHELEQMQLILQTI--PVMR-----DEDHQELLNVIPVFVDKERREPPKPLALLLPNVSKEALDFLQQILTFNPMDRLTAEQALAHPYMS</Hsp_qseq>
      <Hsp_hseq>EYRKIGRGAFGTVVQAYLTQDKKNWLGPFAIKKV----PAHTEYKSRELQILRIADHPNIVKLQYFFTHLSPQDNKV--------YQHLA-MECL---PETLQIEINRYVTNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSISYICSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLREIAKLLGPPDKRFIFFSNPAYDGPLFSKPLFSGSSQQRFEKYFG----HSGPDGIDLLMKILVYEPQQRLSPRRILAHQFFN</Hsp_hseq>
      <Hsp_midline>+ + +G G  G V  A  +   K      AIKK+    P   ++  RE++I+R  DH NIV++   F  L P   ++           LA +EC+    + L+ ++ R +     +  +H RL+ YQ+ RG+ Y+H                    G L                    + +++YR+P L++    YT  ID+W  GC+  EML GK +F G   L Q++ I + +  P  R     +  +   L   P+F    ++   K       +   + +D L +IL + P  RL+  + LAH + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.6481</Hsp_bit-score>
      <Hsp_score>200</Hsp_score>
      <Hsp_evalue>5.37998e-16</Hsp_evalue>
      <Hsp_query-from>1161</Hsp_query-from>
      <Hsp_query-to>1946</Hsp_query-to>
      <Hsp_hit-from>178</Hsp_hit-from>
      <Hsp_hit-to>474</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>131</Hsp_positive>
      <Hsp_gaps>93</Hsp_gaps>
      <Hsp_align-len>326</Hsp_align-len>
      <Hsp_qseq>VFSAVDSDCDKRVAIKKLVLSGPHSLKHALREIKIIRRLDHDNIVRVFEVLGPAGQRLPLGQAGIGTSALAELECVYIVQDYLETDLARVLE-----QGSALSEEHARLFMYQLLRGLKYIH----------------SANGYLSEG---------------------LVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLSGKTLFAGAH-----------ELEQMQLILQTI--------PVMRDEDHQELLNVIPVFVDKERREPPKPLALLLPNVS---KEALDFLQQILTFNPMDRLTAEQALAHPYMSLYAFPQDEPV</Hsp_qseq>
      <Hsp_hseq>VFYAIKKFKTEKDGVEQLHYTGIS--QSACREMALCRELHNKHLTTLVEIF-------------------LERKCVHMVYEYAEHDLLQIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDGCVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELIGLQPIFKGEEAKLDSKKTVPFQVNQLQRILEVLGTPDQKIWPYLEKYPEYDQITKFPKYRDN--------LATWYHSAGGRDKHALSLLYHLLNYDPIKRIDAFNALEHKYFTESDIPVSENV</Hsp_hseq>
      <Hsp_midline>VF A+     ++  +++L  +G    + A RE+ + R L + ++  + E+                     E +CV++V +Y E DL +++      +   +     R  M+QLL G+ Y+H                + +G +  G                     +VT WYR+P LLL   +YT A+D+W+ GCIFAE++  + +F G             ++ Q+Q IL+ +        P +      + +   P + D         LA    +     K AL  L  +L ++P+ R+ A  AL H Y +    P  E V</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YDL079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:312951:314748:-1 gene:YDL079C transcript:YDL079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRK1 description:Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication [Source:SGD;Acc:S000002237]</Hit_def>
  <Hit_accession>YDL079C</Hit_accession>
  <Hit_len>501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.411</Hsp_bit-score>
      <Hsp_score>189</Hsp_score>
      <Hsp_evalue>8.60538e-15</Hsp_evalue>
      <Hsp_query-from>1095</Hsp_query-from>
      <Hsp_query-to>1913</Hsp_query-to>
      <Hsp_hit-from>156</Hsp_hit-from>
      <Hsp_hit-to>447</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>130</Hsp_positive>
      <Hsp_gaps>65</Hsp_gaps>
      <Hsp_align-len>315</Hsp_align-len>
      <Hsp_qseq>HGFELGPRYVDLKPLGFGGNGLVFSAVDSDCDKRVAIKKLVLSGPHSLKHALREIKIIRRLDHDNIVRVFEVLGPAGQRLPLGQAGIGTSALAELECVYI--VQDYLETDLARVLEQGSALSEEHARL----FMYQLLRGLKYIHSANGYLSEGL-----------------------------------VTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLSGKTLFAGAHELEQMQLILQTIPVMRDEDHQELLNVIPVFVDKERRE-PPKPLALLLPNVSKEALDFLQQILTFNPMDRLTAEQALAHPYM</Hsp_qseq>
      <Hsp_hseq>HGGTIDISYPTTEVVGHGSFGVVVTTVIIETNQKVAIKKVL----QDRRYKNRELETMKMLCHPNTV---------GLQYYFYEKD-------EEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQL---VEIIKIMGIPTKDEISGMNPNYEDHVFPNIKPITLAEIFKAEDPDTLDLLTKTLKYHPCERLVPLQCLLSSYF</Hsp_hseq>
      <Hsp_midline>HG  +   Y   + +G G  G+V + V  + +++VAIKK++       ++  RE++ ++ L H N V         G +    +         E + VY+  V DY+   L + L     L  +  R+    + YQL + L Y+H+        +                                    +++YR+P L+    NY+  +D+W++ C+ AE+L GK LF+G   ++Q+   ++ I +M      E+  + P + D       P  LA +      + LD L + L ++P +RL   Q L   Y </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>5.13841e-11</Hsp_evalue>
      <Hsp_query-from>1137</Hsp_query-from>
      <Hsp_query-to>1916</Hsp_query-to>
      <Hsp_hit-from>31</Hsp_hit-from>
      <Hsp_hit-to>273</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>122</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>275</Hsp_align-len>
      <Hsp_qseq>LGFGGNGLVFSAVDSDCDKRVAIKKLVLSGPHSLKHALREIKIIRRLDHDNIVRVFEVLGPAGQRLPLGQAGIGTSALAELECVYIVQDYLET-DLARVLEQGSA-LSEEHARLFMYQLLRGLKYIHSANGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLS-GKTL---------FAGAHELEQMQLILQTIPVM--RDEDHQELLNV-IPVFVDKERREPPKPLALLLPNVSKEALDFLQQILTFNPMDRLTAEQALAHPYMS</Hsp_qseq>
      <Hsp_hseq>IGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYE-------------------LYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLH------GEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSALTLAGTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNPPYHNLTDANIYYAVENDTYYPPSSF-------SEPLKDFLSKCFVKNMYKRPTADQLLKHVWIN</Hsp_hseq>
      <Hsp_midline>+G G  G+V+ A++   D+ VAIK++V      L   + EI +++ L+H+NIV+    +  + +                   +YI+ +Y     L R++ + S  LSE  ++ ++ Q L GLKY+H       EG++ +  ++  +LLS +N  K  D   +  + +  L+   TL           GA  L  +  +  T+  M  ++  +  L +  I   V+ +   PP          S+   DFL +    N   R TA+Q L H +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>3.7173e-10</Hsp_evalue>
      <Hsp_query-from>1197</Hsp_query-from>
      <Hsp_query-to>1727</Hsp_query-to>
      <Hsp_hit-from>94</Hsp_hit-from>
      <Hsp_hit-to>309</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>75</Hsp_gaps>
      <Hsp_align-len>234</Hsp_align-len>
      <Hsp_qseq>VAIKKLVLSGPHSLKH--ALREIKIIRRLD-HDNIVRVFEVLGPAGQRLPLGQAGIGTSALAELECVYIVQDYLETDLARVLE--QGSALSEEHARLFMYQLLRGLKYIHSAN----------------------------GYLSEGLV----------------------TKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLSGKTLFAGAHELEQMQLILQTI--PVMRDE</Hsp_qseq>
      <Hsp_hseq>VAIKTM-MTKLHTLQDYTRVREIKFILAIPANDHLIQIFEVF-----------------IDSENYQLHIVMECMEQNLYQMMKHRRRRVFSIPSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVENKNPYTAYVSTRWYRSPEILLRSGYYSKPLDIWAFGCVAVEVTVFRALFPGANEIDQIWKILEVLGTPIKRSD</Hsp_hseq>
      <Hsp_midline>VAIK + ++  H+L+    +REIK I  +  +D+++++FEV                    +E   ++IV + +E +L ++++  +    S    +  + Q+L GLK+IH  N                            GY    ++                      T+WYRSP +LL    Y+K +D+WA GC+  E+   + LF GA+E++Q+  IL+ +  P+ R +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>6.50932e-07</Hsp_evalue>
      <Hsp_query-from>1026</Hsp_query-from>
      <Hsp_query-to>1709</Hsp_query-to>
      <Hsp_hit-from>331</Hsp_hit-from>
      <Hsp_hit-to>586</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>114</Hsp_positive>
      <Hsp_gaps>62</Hsp_gaps>
      <Hsp_align-len>273</Hsp_align-len>
      <Hsp_qseq>RRLLT--GEGSCQIMAEKFNS-----LQNLHGFELGPRYVDLKPLGFGGNGLVFSAVDSDCDKRVAIKKLVLSGPHSLKHALREIKIIRRLDHDNIVRVFEVLGPAGQR--LPLGQAGIGTSALAELECVYIVQDYLETDLARVLEQGS--ALSEEHARLFMYQLLRGL------KYIHS----ANGYLSEG-----------------------LVTKWYRSPRLLLS-PNNYTKAIDMWAAGCIFAEMLSGKTLFAGAHELEQMQLILQTI</Hsp_qseq>
      <Hsp_hseq>KRVLTKPSEGKCNNGFDNINSDYILYVNDVLGVEQNRKYLVLDILGQGTFGQVVKCQNLLTKEILAVK-VVKSRTEYLTQSITEAKILELLNQK--------IDPTNKHHFLRMYDSFVHKNHLC------LVFELLSNNLYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPELKIIDFGSSCEEARTVYTYIQSRFYRAPEIILGIP--YSTSIDMWSLGCIVAELFLGIPIFPGASEYNQLTRIIDTL</Hsp_hseq>
      <Hsp_midline>+R+LT   EG C    +  NS     + ++ G E   +Y+ L  LG G  G V    +    + +A+K +V S    L  ++ E KI+  L+          + P  +   L +  + +  + L       +V + L  +L  +L+Q     LS +  R F  Q+L  L      K IH      N  L                          + +++YR+P ++L  P  Y+ +IDMW+ GCI AE+  G  +F GA E  Q+  I+ T+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YIL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:287790:288908:-1 gene:YIL035C transcript:YIL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA1 description:Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000001297]</Hit_def>
  <Hit_accession>YIL035C</Hit_accession>
  <Hit_len>372</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>9.18641e-07</Hsp_evalue>
      <Hsp_query-from>1281</Hsp_query-from>
      <Hsp_query-to>1916</Hsp_query-to>
      <Hsp_hit-from>130</Hsp_hit-from>
      <Hsp_hit-to>364</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>67</Hsp_gaps>
      <Hsp_align-len>257</Hsp_align-len>
      <Hsp_qseq>HDNIVRVFEVLGPAGQRLPLGQAGIGTSALAELECVYIVQDYLETDLARVLEQGSALSEEHARLFMYQLLRGLKYIHS----------------------------------ANGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLSGKT-LFAGAHELEQMQLILQTIPVMRDEDHQELLNVIPVFVDKERREPP----KPLALLLPNVSK------EALDFLQQILTFNPMDRLTAEQALAHPYMS</Hsp_qseq>
      <Hsp_hseq>HANIIHLFDIIKDPISKTPA-----------------LVFEYVDNVDFRIL--YPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQL---VKIVKVLGTSDFEKYLLKYEITLPREFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWFA</Hsp_hseq>
      <Hsp_midline>H NI+ +F+++     + P                  +V +Y++    R+L     L++   R +M++LL+ L Y HS                                   N   +  + +++++ P LL+    Y  ++D+W+ G + A M+  +   F G    +Q+   ++ + V+   D ++ L    + + +E  +      KP    + + +K      E +D +  +L ++  +RLTA++A+ HP+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>2.28981e-06</Hsp_evalue>
      <Hsp_query-from>1479</Hsp_query-from>
      <Hsp_query-to>1910</Hsp_query-to>
      <Hsp_hit-from>1322</Hsp_hit-from>
      <Hsp_hit-to>1439</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>144</Hsp_align-len>
      <Hsp_qseq>YQLLRGLKYIHSANGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLSGKTLFAGAHELEQMQLILQTIPVMRDEDHQELLNVIPVFVDKERREPPKPLALLLPNVSKEALDFLQQILTFNPMDRLTAEQALAHPY</Hsp_qseq>
      <Hsp_hseq>FGISRKSKDIYSNSDMTMRGTV--FWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSN---LEVVAAMFK--------------------IGKSKSAPPIP-EDTLPLISQIGRNFLDACFEINPEKRPTANELLSHPF</Hsp_hseq>
      <Hsp_midline>+ + R  K I+S +     G V  ++ +P ++ +   Y+  +D+W+ GCI  EM +GK  ++    LE +  + +                    + K +  PP P    LP +S+   +FL      NP  R TA + L+HP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>4.31178e-06</Hsp_evalue>
      <Hsp_query-from>1137</Hsp_query-from>
      <Hsp_query-to>1628</Hsp_query-to>
      <Hsp_hit-from>1272</Hsp_hit-from>
      <Hsp_hit-to>1415</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>169</Hsp_align-len>
      <Hsp_qseq>LGFGGNGLVFSAVDSDCDKRVAIKKLVLSGPHSLKHAL----REIKIIRRLDHDNIVRVFEVLGPAGQRLPLGQAGIGTSALAELECVYIVQDYLET-DLARVLEQGSALSEEHARLFMYQLLRGLKYIHSANGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCI</Hsp_qseq>
      <Hsp_hseq>IGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGVE-------------------VHRDKVNIFMEYCEGGSLAALLEHGRIEDEMVTQVYTLQLLEGLAYLHES------GIVHRDVKPENILLDFNGVIKYVDFGAAKKI</Hsp_hseq>
      <Hsp_midline>+G G  G V+SAVD D  + +A+K++ +    S++        E+ ++  L+H NIV  + V                       + V I  +Y E   LA +LE G    E   +++  QLL GL Y+H +      G+V +  +   +LL  N   K +D  AA  I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>105</Statistics_hsp-len>
      <Statistics_eff-space>4379944124</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052660-RA transcript Note:&quot;Similar to Atr Serine/threonine-protein kinase ATR (Mus musculus)&quot; offset:0 AED:0.23 eAED:0.25 QI:0|0.22|0.28|0.78|0.77|0.75|28|2053|1335</Iteration_query-def>
  <Iteration_query-len>6061</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YBR136W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:505668:512774:1 gene:YBR136W transcript:YBR136W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEC1 description:Genome integrity checkpoint protein and PI kinase superfamily member; Mec1p and Dun1p function in same pathway to regulate dNTP pools and telomere length; signal transducer required for cell cycle arrest and transcriptional responses to damaged or unreplicated DNA; facilitates replication fork progression and regulates P-body formation under replication stress; promotes interhomolog recombination by phosphorylating Hop1p; associates with shortened, dysfunctional telomeres [Source:SGD;Acc:S000000340]</Hit_def>
  <Hit_accession>YBR136W</Hit_accession>
  <Hit_len>2368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>306.22</Hsp_bit-score>
      <Hsp_score>783</Hsp_score>
      <Hsp_evalue>5.34229e-84</Hsp_evalue>
      <Hsp_query-from>1909</Hsp_query-from>
      <Hsp_query-to>4002</Hsp_query-to>
      <Hsp_hit-from>1621</Hsp_hit-from>
      <Hsp_hit-to>2367</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>214</Hsp_identity>
      <Hsp_positive>367</Hsp_positive>
      <Hsp_gaps>103</Hsp_gaps>
      <Hsp_align-len>774</Hsp_align-len>
      <Hsp_qseq>IIRLHMLSELEHSVSRLSAGENLENRSVWSSAWQARLEVTQNSFRAKEPILELRRAL--LCLAGDSDALVGECWLQSARVARKAGHYQTAYNALLNARAVHPPDLCVERARWLWIQGKVHQALLQLQRSVEQHVGGEGCRPSDPRQTAVLARAFLLIGRLMEETANFESNAIVKQYKEVTSLLPDWEDGHFYLAKYYDKLMPTMTDNRMEKQGDIIYRIVYHFGRSLMFGNQFIYQSMPRLLSLWLDFGAKVFELERGNRSERQHLPVAADLAKIIKIMTEHTQKLAPYQFLTAFSQLISRICHPHAAVCAALQAIIVKVLTRYPQQALWMMMA------------------------------VSKTMDKQTTMS-------MNVNFRGLKRLVDDTNF------SNVLIPLQAVMTPTLPSTPGGHADHDPFPGNMAYIVGFHDPVEVLSSLQKPKKICIRGSDGRSYPMMCKPKDDLRKDCRLMEFNSLIN-------------------------KECGLVEWVNNTESLRTIVDILYNEKGIGLTMSEVSKCILPIETPLEQKLSMYRDKLLPPHPPVFHEWFLRTFPDPTSWYSSRLGYTRSTAVMSMVGYVLGLGDRHGENILFDSLTGECMHVDFNCLFNKGLTFGVPELVPFRLTHNMVHAMGPMGLEGLFRRACEVTMRVMCDQRESLIRSGLPSALYWPEAKQIVQDIEQRLHGVIKNPNNRVR------GLPLSIEGHVHYLIQEATNEKLLCQMYLGWAPF</Hsp_qseq>
      <Hsp_hseq>LMKLHSLYDL----SFLSSAKDKFEYKSNTTILDYRMERIGADFVPNHYILSMRKSFDQLKMNEQADADLGKTFFTLAQLARNNARLDIASESLMHCLERRLPQAELEFAEILWKQGENDRALKIVQEIHEKYQENSSVNARD--RAAVLLK----FTEWLDLSNNSASEQIIKQYQDIFQIDSKWDKPYYSIGLYYSRLLERKKAEGYITNGRFEYRAISYFLLAFEKNTAKVRENLPKVITFWLDIAAASISEAPGNRKEM----LSKATEDICSHVEEALQHCPTYIWYFVLTQLLSRLLHSHQSSAQIIMHILLSLAVEYPSHILWYITALVNSNSSKRVLRGKHILEKYRQHSQNPHDLVSSALDLTKALTRVCLQDVKSITSRSGKSLEKDFKFDMNVAPSAMVVPVRKNLDIISPLESNSMRGYQPFRPVVS-IIRFGSSYKVFSSLKKPKQLNIIGSDGNIYGIMCK-KEDVRQDNQYMQFATTMDFLLSKDIASRKRSLGINIYSVLSLREDCGILEMVPNVVTLRSILSTKYESLKIKYSLKSLHDRWQ--HTAVDGKLEFYMEQV-DKFPPILYQWFLENFPDPINWFNARNTYARSYAVMAMVGHILGLGDRHCENILLDIQTGKVLHVDFDCLFEKGKRLPVPEIVPFRLTPNLLDALGIIGTEGTFKKSSEVTLALM-RKNEVALMNVIETIMY-------DRNMDHSIQKALKVLRNKIRGIDPQDGLVLSVAGQTETLIQEATSEDNLSKMYIGWLPF</Hsp_hseq>
      <Hsp_midline>+++LH L +L    S LS+ ++       ++    R+E     F     IL +R++   L +   +DA +G+ +   A++AR       A  +L++      P   +E A  LW QG+  +AL  +Q   E++         D  + AVL +        ++ + N  S  I+KQY+++  +   W+  ++ +  YY +L+           G   YR + +F  +       + +++P++++ WLD  A       GNR E     ++     I   + E  Q    Y +    +QL+SR+ H H +    +  I++ +   YP   LW + A                              VS  +D    ++        ++  R  K L  D  F      S +++P++  +    P        + PF   ++ I+ F    +V SSL+KPK++ I GSDG  Y +MCK K+D+R+D + M+F + ++                         ++CG++E V N  +LR+I+   Y    I  ++  +        T ++ KL  Y +++    PP+ ++WFL  FPDP +W+++R  Y RS AVM+MVG++LGLGDRH ENIL D  TG+ +HVDF+CLF KG    VPE+VPFRLT N++ A+G +G EG F+++ EVT+ +M  + E  + + + + +Y        ++++  +   +K   N++R      GL LS+ G    LIQEAT+E  L +MY+GW PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YBL088C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:51019:59382:-1 gene:YBL088C transcript:YBL088C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TEL1 description:Protein kinase primarily involved in telomere length regulation; contributes to cell cycle checkpoint control in response to DNA damage; acts with Red1p and Mec1p to promote interhomolog recombination by phosphorylation of Hop1; functionally redundant with Mec1p; regulates P-body formation induced by replication stress; homolog of human ataxia-telangiectasia mutated (ATM) gene [Source:SGD;Acc:S000000184]</Hit_def>
  <Hit_accession>YBL088C</Hit_accession>
  <Hit_len>2787</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>168.703</Hsp_bit-score>
      <Hsp_score>426</Hsp_score>
      <Hsp_evalue>4.56626e-42</Hsp_evalue>
      <Hsp_query-from>2533</Hsp_query-from>
      <Hsp_query-to>4005</Hsp_query-to>
      <Hsp_hit-from>2220</Hsp_hit-from>
      <Hsp_hit-to>2787</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>146</Hsp_identity>
      <Hsp_positive>252</Hsp_positive>
      <Hsp_gaps>127</Hsp_gaps>
      <Hsp_align-len>593</Hsp_align-len>
      <Hsp_qseq>KQGDIIYRIVYHFGRSLMFGNQFIYQSMPRLLSLWLDFGAKVFELERGNRSERQHLPVAADLAKIIKIMTEHTQKLAPYQFLTAFSQLISRICHPHAAVCAALQAIIVKVLTRYPQQALWMMMAV---SKTMDKQTTMS----------------------------------MNVNFRGLKRLVDDTN---FSNVLIP---LQAVMTPTLPSTPGGHADHDPFPGNMA--YIVGFHDPVEVLSS-LQKPKKICIRGSDGRSYPMMCK-PKDDLRKDCRLMEFNSLINK-------------------------ECGLVEWVNNTESLRTIVDILYNEKGIGLTMSEVSKCILPIETPL-EQKLSMYRDKLLPPHPPVFHEWFLRTFPDPTSWYSSRLGYTRSTAVMSMVGYVLGLGDRHGENILFDSLTGECMHVDFNCLFNKGLTFGVPELVPFRLTHNMVHAMGPMGLEGLFRRACEVT--------MRVMC-------DQRESLIRSGLPSALYWPEAKQIVQDIE--------------QRLHGVIKNPNNRVRGLPLSIEGHVHYLIQEATNEKLLCQMYLGWAPFH</Hsp_qseq>
      <Hsp_hseq>QKEKFLWHALHFYLNTLVFSNRYDNDIIDKFCGLWFE---------------------NDDNSKINQLLYKEIGTIPSWKFLPWVNQIASKISMEENEFQKPLQLTMKRLLYKLPYDSLYSVMSILLYEKQSNKDTNISQKIQAVKKILLELQGYDRGAFAKKYLLPVQEFCEMSVELANLK-FVQNTKTLRLANLKIGQYWLKQLNMEKLPLPTSNFTVKSSADGRKARPYIVSVNETVGITTTGLSLPKIVTFNISDGTTQKALMKGSNDDLRQDAIMEQVFQQVNKVLQNDKVLRNLDLGIRTYKVVPLGPKAGIIEFVANSTSLHQILSKLHTNDKI--TFDQARKGMKAVQTKSNEERLKAYL-KITNEIKPQLRNFFFDSFPDPLDWFEAKKTYTKGVAASSIVGYILGLGDRHLNNILLDCSTGEPIHIDLGIAFDQGKLLPIPELVPFRLTRDIVDGFGVTGVDGLFRRSCERVYAVLRKDYVKVMCVLNILKWDPLYSWVMSPVKKYEHLFEEEHEITNFDNVSKFISNNDRNENQESYRALKGVEEKLMGNGLSVESSVQDLIQQATDPSNLSVIYMGWSPFY</Hsp_hseq>
      <Hsp_midline>++   ++  ++ +  +L+F N++    + +   LW +                       D +KI +++ +    +  ++FL   +Q+ S+I          LQ  + ++L + P  +L+ +M++    K  +K T +S                                  M+V    LK  V +T     +N+ I    L+ +    LP             G  A  YIV  ++ V + ++ L  PK +    SDG +   + K   DDLR+D  + +    +NK                         + G++E+V N+ SL  I+  L+    I  T  +  K +  ++T   E++L  Y  K+     P    +F  +FPDP  W+ ++  YT+  A  S+VGY+LGLGDRH  NIL D  TGE +H+D    F++G    +PELVPFRLT ++V   G  G++GLFRR+CE          ++VMC       D   S + S +    +  E +  + + +              Q  +  +K    ++ G  LS+E  V  LIQ+AT+   L  +Y+GW+PF+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YJR066W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:559416:566828:1 gene:YJR066W transcript:YJR066W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOR1 description:PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that controls growth in response to nutrients by regulating translation, transcription, ribosome biogenesis, nutrient transport and autophagy; involved in meiosis; TOR1 has a paralog, TOR2, that arose from the whole genome duplication [Source:SGD;Acc:S000003827]</Hit_def>
  <Hit_accession>YJR066W</Hit_accession>
  <Hit_len>2470</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>159.458</Hsp_bit-score>
      <Hsp_score>402</Hsp_score>
      <Hsp_evalue>2.73311e-39</Hsp_evalue>
      <Hsp_query-from>3040</Hsp_query-from>
      <Hsp_query-to>4002</Hsp_query-to>
      <Hsp_hit-from>2076</Hsp_hit-from>
      <Hsp_hit-to>2469</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>119</Hsp_identity>
      <Hsp_positive>180</Hsp_positive>
      <Hsp_gaps>83</Hsp_gaps>
      <Hsp_align-len>399</Hsp_align-len>
      <Hsp_qseq>STPGGHADHDPFPGNMAYIVGFHDPV-EVLSSLQKPKKICIRGSDGRSYPMMCKPKDDLRKDCRLMEFNSLIN------KEC-------------------GLVEWVNNTESLRTIVDILYNEKGIGLTMSE-VSKCILPI--ETPLEQKLSMYRDKLLPPHPPVFHEWFLRTFPDPTSWYSSRLGYTRSTAVMSMVGYVLGLGDRHGENILFDSLTGECMHVDF-NCLFNKGLTFGVPELVPFRLTHNMVHAMGPMGLEGLFRRACEVTMRVMCDQRESLI-------------------------RSGLPSALYWP-----------------EAKQIVQDIEQRLHGVIKNPNNRVRG------LPLSIEGHVHYLIQEATNEKLLCQMYLGWAPF</Hsp_qseq>
      <Hsp_hseq>AVPGTY-----FPGKPTIRIAKFEPLFSVISSKQRPRKFSIKGSDGKDYKYVLKGHEDIRQDSLVMQLFGLVNTLLKNDSECFKRHLDIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHRDAKKIPLNIEHWVMLQMAPDYENLTLLQKIEVFTYALDNTKGQDLYKILWLKSRSSETWLERRTTYTRSLAVMSMTGYILGLGDRHPSNLMLDRITGKVIHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMRVLRDNKESLMAILEAFALDPLIHWGFDLPPQKLTEQTGIPLPLINPSELLRKGAITVEEAANMEAEQQNETKNARAMLVLRRITDKLTGNDIKRFNELDVPEQVDKLIQQATSIERLCQHYIGWCPF</Hsp_hseq>
      <Hsp_midline>+ PG +     FPG     +   +P+  V+SS Q+P+K  I+GSDG+ Y  + K  +D+R+D  +M+   L+N       EC                   GL+ WV N+++   ++    + K I L +   V   + P      L QK+ ++   L        ++          +W   R  YTRS AVMSM GY+LGLGDRH  N++ D +TG+ +H+DF +C     L    PE VPFRLT  + +AM   G+EG FR  CE  MRV+ D +ESL+                         ++G+P  L  P                 EA+Q  +    R   V++   +++ G        L +   V  LIQ+AT+ + LCQ Y+GW PF</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>1.15628e-07</Hsp_evalue>
      <Hsp_query-from>1690</Hsp_query-from>
      <Hsp_query-to>2499</Hsp_query-to>
      <Hsp_hit-from>1467</Hsp_hit-from>
      <Hsp_hit-to>1746</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>114</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>289</Hsp_align-len>
      <Hsp_qseq>AAWKLTQWGDLETCLTNETYGSWSIGLGKLLLAAKQCDRVTLERQLKVVRAEQMVPLSAASLERGSYQRGYEYIIRLHMLSELEHSVSRLSAGENLENRSVWSSAWQARLEVTQNSFRAKEPILELRRALLCLAGDSDALVGECWLQSARVARKAGHYQTAYNAL-----------LNARAVHPPDLCVERARWLWIQGKVHQALLQLQRSVEQHVGGEGCRPSD-PRQTAVLARAFLLIGRLMEETANFESNAIVKQYKEVTSLLPDWED-------GHFYLAKYYDK</Hsp_qseq>
      <Hsp_hseq>AAWGLGEWDMLEQYISVMKPKSPDKEFFDAILYLHKNDYDNASKH--ILNARDLLVTEISALINESYNRAYSVIVRTQIITEFEEIIKYKQLPPNSEKKLHYQNLWTKRLLGCQKNVDLWQRVLRVRSLVIKPKQDL-----QIWIKFANLCRKSGRMRLANKALNMLLEGGNDPSLPNTFKAPPPVVYAQLKYIWATGAYKEALNHLIGFTSRLAHDLGLDPNNMIAQSVKLSSAS--TAPYVEEYTKLLARCFLKQGEWRIATQPNWRNTNPDAILGSYLLATHFDK</Hsp_hseq>
      <Hsp_midline>AAW L +W  LE  ++     S        +L   + D     +   ++ A  ++    ++L   SY R Y  I+R  +++E E  +       N E +  + + W  RL   Q +    + +L +R  ++    D      + W++ A + RK+G  + A  AL           L      PP +   + +++W  G   +AL  L     +     G  P++   Q+  L+ A       +EE     +   +KQ +   +  P+W +       G + LA ++DK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YKL203C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:55935:63359:-1 gene:YKL203C transcript:YKL203C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOR2 description:PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth in response to nutrients and TORC2, a complex that regulates cell-cycle dependent polarization of the actin cytoskeleton; involved in meiosis; TOR2 has a paralog, TOR1, that arose from the whole genome duplication [Source:SGD;Acc:S000001686]</Hit_def>
  <Hit_accession>YKL203C</Hit_accession>
  <Hit_len>2474</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>152.525</Hsp_bit-score>
      <Hsp_score>384</Hsp_score>
      <Hsp_evalue>3.58717e-37</Hsp_evalue>
      <Hsp_query-from>3094</Hsp_query-from>
      <Hsp_query-to>4002</Hsp_query-to>
      <Hsp_hit-from>2094</Hsp_hit-from>
      <Hsp_hit-to>2473</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>114</Hsp_identity>
      <Hsp_positive>166</Hsp_positive>
      <Hsp_gaps>77</Hsp_gaps>
      <Hsp_align-len>380</Hsp_align-len>
      <Hsp_qseq>IVGFHDPVEVLSSLQKPKKICIRGSDGRSYPMMCKPKDDLRKDCRLMEFNSLINK------EC-------------------GLVEWVNNTESLRTIVDILYNEKGIGLTMSE-VSKCILPI--ETPLEQKLSMYRDKLLPPHPPVFHEWFLRTFPDPTSWYSSRLGYTRSTAVMSMVGYVLGLGDRHGENILFDSLTGECMHVDF-NCLFNKGLTFGVPELVPFRLTHNMVHAMGPMGLEGLFRRACEVTMRVMCDQRESLIR--------------SGLPSALYWPE-------------------AKQIVQDIEQRLHGVIKNP---------------NNRVRGLPLSIEGHVHYLIQEATNEKLLCQMYLGWAPF</Hsp_qseq>
      <Hsp_hseq>ISKFEPVFSVISSKQRPRKFCIKGSDGKDYKYVLKGHEDIRQDSLVMQLFGLVNTLLQNDAECFRRHLDIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHREAKKIPLNIEHWVMLQMAPDYDNLTLLQKVEVFTYALNNTEGQDLYKVLWLKSRSSETWLERRTTYTRSLAVMSMTGYILGLGDRHPSNLMLDRITGKVIHIDFGDCFEAAILREKFPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMKVLRDNKGSLMAILEAFAFDPLINWGFDLPTKKIEEETGIQLPVMNANELLSNGAITEEEVQRVENEHKNAIRNARAMLVLKRITDKLTGNDIRRFNDLDVPEQVDKLIQQATSVENLCQHYIGWCPF</Hsp_hseq>
      <Hsp_midline>I  F     V+SS Q+P+K CI+GSDG+ Y  + K  +D+R+D  +M+   L+N       EC                   GL+ WV N+++   ++      K I L +   V   + P      L QK+ ++   L        ++          +W   R  YTRS AVMSM GY+LGLGDRH  N++ D +TG+ +H+DF +C     L    PE VPFRLT  + +AM   G+EG FR  CE  M+V+ D + SL+                 LP+     E                    ++ VQ +E      I+N                N+  R   L +   V  LIQ+AT+ + LCQ Y+GW PF</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>5.51724e-06</Hsp_evalue>
      <Hsp_query-from>1822</Hsp_query-from>
      <Hsp_query-to>2496</Hsp_query-to>
      <Hsp_hit-from>1516</Hsp_hit-from>
      <Hsp_hit-to>1752</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>244</Hsp_align-len>
      <Hsp_qseq>QLKVVRAEQMVPLSAASLERGSYQRGYEYIIRLHMLSELEHSVSRLSAGENLENRSVWSSAWQARLEVTQNSFRAKEPILELRRALLCLAGDSDALVGECWLQSARVARKAGHYQTA---YNALL---------NARAVHPPDLCVERARWLWIQGKVHQALLQLQRSVEQHVGGEGCRPSDPRQTAVLARAFLLIGRLMEETANFESNAIVKQYKEVTSLLPDWE-------DGHFYLAKYYD</Hsp_qseq>
      <Hsp_hseq>EVHIFNARDLLVTELSALVNESYNRAYNVVVRAQIIAELEEIIKYKKLPQNSDKRLTMRETWNTRLLGCQKNIDVWQRILRVRS--LVIKPKEDAQVR---IKFANLCRKSGRMALAKKVLNTLLEETDDPDHPNTAKASPP-VVYAQLKYLWATGLQDEALKQLINFTSRMAHDLGLDPNNMIAQSVPQQS-KRVPRHVEDYTKLLARCFLKQGEWRVCLQPKWRLSNPDSILGSYLLATHFD</Hsp_hseq>
      <Hsp_midline>++ +  A  ++    ++L   SY R Y  ++R  +++ELE  +      +N + R      W  RL   Q +    + IL +R   L +    DA V    ++ A + RK+G    A    N LL         N     PP +   + ++LW  G   +AL QL     +     G  P++    +V  ++   + R +E+     +   +KQ +    L P W         G + LA ++D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YLR305C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:738161:743863:-1 gene:YLR305C transcript:YLR305C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STT4 description:Phosphatidylinositol-4-kinase; functions in the Pkc1p protein kinase pathway; required for normal vacuole morphology, cell wall integrity, and actin cytoskeleton organization [Source:SGD;Acc:S000004296]</Hit_def>
  <Hit_accession>YLR305C</Hit_accession>
  <Hit_len>1900</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>3.03155e-10</Hsp_evalue>
      <Hsp_query-from>3406</Hsp_query-from>
      <Hsp_query-to>3714</Hsp_query-to>
      <Hsp_hit-from>1699</Hsp_hit-from>
      <Hsp_hit-to>1802</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>108</Hsp_align-len>
      <Hsp_qseq>SMYRDKLLPPHPPVFHEWFLRTFPDPTS--WYSSRLGYTRSTAVMSMVGYVLGLGDRHGENILFDSLTGECMHVDFNCLFN---KGLTFGVPELVPFRLTHNMVHAMG</Hsp_qseq>
      <Hsp_hseq>SVSRDMLGREAVNGLYEYFTSKFGNESTIEFQNARNNFVKSLAGYSVISYLLQFKDRHNGNIMYDD-QGHCLHIDFGFIFDIVPGGIKF---EAVPFKLTKEMVKVMG</Hsp_hseq>
      <Hsp_midline>S+ RD L        +E+F   F + ++  + ++R  + +S A  S++ Y+L   DRH  NI++D   G C+H+DF  +F+    G+ F   E VPF+LT  MV  MG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YNL267W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:140878:144078:1 gene:YNL267W transcript:YNL267W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PIK1 description:Phosphatidylinositol 4-kinase; catalyzes first step in the biosynthesis of phosphatidylinositol-4,5-biphosphate; may control cytokinesis through the actin cytoskeleton; may control nonselective autophagy and mitophagy through trafficking of Atg9p [Source:SGD;Acc:S000005211]</Hit_def>
  <Hit_accession>YNL267W</Hit_accession>
  <Hit_len>1066</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>8.72003e-08</Hsp_evalue>
      <Hsp_query-from>3448</Hsp_query-from>
      <Hsp_query-to>3780</Hsp_query-to>
      <Hsp_hit-from>877</Hsp_hit-from>
      <Hsp_hit-to>993</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>120</Hsp_align-len>
      <Hsp_qseq>FHEWFLRTFPDPTSWYSSRL--GYTRSTAVMSMVGYVLGLGDRHGENILFDSLTGECMHVDFNCLFNKGLTFGVPELVPFRLTHNMVHAMGPMGLEG-LFRRACEVT------MRVMCDQ</Hsp_qseq>
      <Hsp_hseq>LNDHFLRAFGNPNGFKYRRAQDNFASSLAAYSVICYLLQVKDRHNGNIMIDN-EGHVSHIDFGFMLSNSPGSVGFEAAPFKLTYEYIELLG--GVEGEAFKKFVELTKSSFKALRKYADQ</Hsp_hseq>
      <Hsp_midline> ++ FLR F +P  +   R    +  S A  S++ Y+L + DRH  NI+ D+  G   H+DF  + +        E  PF+LT+  +  +G  G+EG  F++  E+T      +R   DQ</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>105</Statistics_hsp-len>
      <Statistics_eff-space>4253343305</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052663-RA transcript Note:&quot;Similar to CSPG4 Chondroitin sulfate proteoglycan 4 (Homo sapiens)&quot; offset:0 AED:0.03 eAED:0.04 QI:0|0|0|0.83|1|1|12|0|2418</Iteration_query-def>
  <Iteration_query-len>7257</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>106</Statistics_hsp-len>
      <Statistics_eff-space>5122062171</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

