<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0053980-RA transcript Note:&quot;Similar to IFT57 Intraflagellar transport protein 57 homolog (Bos taurus)&quot; offset:0 AED:0.11 eAED:0.11 QI:0|0.57|0.75|1|0.28|0.25|8|2608|281</BlastOutput_query-def>
  <BlastOutput_query-len>3454</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053980-RA transcript Note:&quot;Similar to IFT57 Intraflagellar transport protein 57 homolog (Bos taurus)&quot; offset:0 AED:0.11 eAED:0.11 QI:0|0.57|0.75|1|0.28|0.25|8|2608|281</Iteration_query-def>
  <Iteration_query-len>3454</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2369024417</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053959-RA transcript Note:&quot;Similar to Plbd1 Phospholipase B-like 1 (Rattus norvegicus)&quot; offset:163 AED:0.21 eAED:0.23 QI:163|0.62|0.77|1|1|1|9|1572|418</Iteration_query-def>
  <Iteration_query-len>2992</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>2030078966</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053962-RA transcript Note:&quot;Similar to inlA Internalin A (Listeria monocytogenes serotype 1/2a (strain 10403S))&quot; offset:1078 AED:0.41 eAED:0.41 QI:1078|0.5|0.71|0.85|0.83|0.71|7|0|165</Iteration_query-def>
  <Iteration_query-len>1576</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>988570477</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053963-RA transcript Note:&quot;Similar to ZNF148 Zinc finger protein 148 (Homo sapiens)&quot; offset:2040 AED:0.13 eAED:0.15 QI:2040|0|0.5|1|0|0.5|2|0|345</Iteration_query-def>
  <Iteration_query-len>3078</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YOR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:534075:536819:1 gene:YOR113W transcript:YOR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AZF1 description:Zinc-finger transcription factor; involved in diauxic shift; in the presence of glucose, activates transcription of genes involved in growth and carbon metabolism; in nonfermentable carbon sources, activates transcription of genes involved in maintenance of cell wall integrity; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000005639]</Hit_def>
  <Hit_accession>YOR113W</Hit_accession>
  <Hit_len>914</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>2.554e-11</Hsp_evalue>
      <Hsp_query-from>2851</Hsp_query-from>
      <Hsp_query-to>3021</Hsp_query-to>
      <Hsp_hit-from>615</Hsp_hit-from>
      <Hsp_hit-to>671</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>35</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>57</Hsp_align-len>
      <Hsp_qseq>HSSAKPFGCRECGARFATKYNLRVHERRHTGERPFACEVCGRRFSRSYCLGRHKRCH</Hsp_qseq>
      <Hsp_hseq>HIGYKPFVCDYCGKRFTQGGNLRTHERLHTGEKPYSCDICDKKFSRKGNLAAHLVTH</Hsp_hseq>
      <Hsp_midline>H   KPF C  CG RF    NLR HER HTGE+P++C++C ++FSR   L  H   H</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>7.50626e-06</Hsp_evalue>
      <Hsp_query-from>2857</Hsp_query-from>
      <Hsp_query-to>3021</Hsp_query-to>
      <Hsp_hit-from>589</Hsp_hit-from>
      <Hsp_hit-to>643</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>30</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>55</Hsp_align-len>
      <Hsp_qseq>SAKPFGCRECGARFATKYNLRVHERRHTGERPFACEVCGRRFSRSYCLGRHKRCH</Hsp_qseq>
      <Hsp_hseq>AVKKHECPYCHRLFSQATHLEVHVRSHIGYKPFVCDYCGKRFTQGGNLRTHERLH</Hsp_hseq>
      <Hsp_midline>+ K   C  C   F+   +L VH R H G +PF C+ CG+RF++   L  H+R H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YJL056C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:330431:333073:-1 gene:YJL056C transcript:YJL056C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZAP1 description:Zinc-regulated transcription factor; binds to zinc-responsive promoters to induce transcription of certain genes in presence of zinc, represses other genes in low zinc; regulates its own transcription; contains seven zinc-finger domains [Source:SGD;Acc:S000003592]</Hit_def>
  <Hit_accession>YJL056C</Hit_accession>
  <Hit_len>880</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>9.5673e-11</Hsp_evalue>
      <Hsp_query-from>2851</Hsp_query-from>
      <Hsp_query-to>3021</Hsp_query-to>
      <Hsp_hit-from>790</Hsp_hit-from>
      <Hsp_hit-to>846</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>25</Hsp_identity>
      <Hsp_positive>37</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>57</Hsp_align-len>
      <Hsp_qseq>HSSAKPFGCRECGARFATKYNLRVHERRHTGERPFACEVCGRRFSRSYCLGRHKRCH</Hsp_qseq>
      <Hsp_hseq>HSGEKPYKCHICNKKFAISSSLKIHIRTHTGEKPLQCKICGKRFNESSNLSKHIKTH</Hsp_hseq>
      <Hsp_midline>HS  KP+ C  C  +FA   +L++H R HTGE+P  C++CG+RF+ S  L +H + H</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>1.02499e-07</Hsp_evalue>
      <Hsp_query-from>2851</Hsp_query-from>
      <Hsp_query-to>3021</Hsp_query-to>
      <Hsp_hit-from>762</Hsp_hit-from>
      <Hsp_hit-to>818</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>22</Hsp_identity>
      <Hsp_positive>34</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>57</Hsp_align-len>
      <Hsp_qseq>HSSAKPFGCRECGARFATKYNLRVHERRHTGERPFACEVCGRRFSRSYCLGRHKRCH</Hsp_qseq>
      <Hsp_hseq>HSKYKPYKCKTCKRCFSSEETLVQHTRTHSGEKPYKCHICNKKFAISSSLKIHIRTH</Hsp_hseq>
      <Hsp_midline>HS  KP+ C+ C   F+++  L  H R H+GE+P+ C +C ++F+ S  L  H R H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YNL027W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:579580:581616:1 gene:YNL027W transcript:YNL027W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CRZ1 description:Transcription factor, activates transcription of stress response genes; nuclear localization is positively regulated by calcineurin-mediated dephosphorylation; rapidly localizes to the nucleus under blue light stress; can be activated in stochastic pulses of nuclear localization in response to calcium [Source:SGD;Acc:S000004972]</Hit_def>
  <Hit_accession>YNL027W</Hit_accession>
  <Hit_len>678</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>1.57869e-10</Hsp_evalue>
      <Hsp_query-from>2869</Hsp_query-from>
      <Hsp_query-to>3024</Hsp_query-to>
      <Hsp_hit-from>569</Hsp_hit-from>
      <Hsp_hit-to>620</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>31</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>52</Hsp_align-len>
      <Hsp_qseq>FGCRECGARFATKYNLRVHERRHTGERPFACEVCGRRFSRSYCLGRHKRCHV</Hsp_qseq>
      <Hsp_hseq>FACDVCGKKFTRPYNLKSHLRTHTNERPFICSICGKAFARQHDRKRHEDLHT</Hsp_hseq>
      <Hsp_midline>F C  CG +F   YNL+ H R HT ERPF C +CG+ F+R +   RH+  H </Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>9.71114e-07</Hsp_evalue>
      <Hsp_query-from>2851</Hsp_query-from>
      <Hsp_query-to>3009</Hsp_query-to>
      <Hsp_hit-from>591</Hsp_hit-from>
      <Hsp_hit-to>652</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>36</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>62</Hsp_align-len>
      <Hsp_qseq>HSSAKPFGCRECGARFATKYNLRVHERRHTGERPFAC---------EVCGRRFSRSYCLGRH</Hsp_qseq>
      <Hsp_hseq>HTNERPFICSICGKAFARQHDRKRHEDLHTGKKRYVCGGKLKDGKPWGCGKKFARSDALGRH</Hsp_hseq>
      <Hsp_midline>H++ +PF C  CG  FA +++ + HE  HTG++ + C           CG++F+RS  LGRH</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YMR037C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:344403:346517:-1 gene:YMR037C transcript:YMR037C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MSN2 description:Stress-responsive transcriptional activator; activated in stochastic pulses of nuclear localization in response to various stress conditions; binds DNA at stress response elements of responsive genes; relative distribution to nucleus increases upon DNA replication stress [Source:SGD;Acc:S000004640]</Hit_def>
  <Hit_accession>YMR037C</Hit_accession>
  <Hit_len>704</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>2.55712e-08</Hsp_evalue>
      <Hsp_query-from>2863</Hsp_query-from>
      <Hsp_query-to>3021</Hsp_query-to>
      <Hsp_hit-from>645</Hsp_hit-from>
      <Hsp_hit-to>698</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>32</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>54</Hsp_align-len>
      <Hsp_qseq>KPFGCRECGARFATKYNLRVHERR-HTGERPFACEVCGRRFSRSYCLGRHKRCH</Hsp_qseq>
      <Hsp_hseq>KPFHCHICPKSFKRSEHLKRHVRSVHSNERPFACHICDKKFSRSDNLSQHIKTH</Hsp_hseq>
      <Hsp_midline>KPF C  C   F    +L+ H R  H+ ERPFAC +C ++FSRS  L +H + H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YKL062W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:323228:325120:1 gene:YKL062W transcript:YKL062W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MSN4 description:Stress-responsive transcriptional activator; activated in stochastic pulses of nuclear localization in response to various stress conditions; binds DNA at stress response elements of responsive genes, inducing gene expression; involved in diauxic shift [Source:SGD;Acc:S000001545]</Hit_def>
  <Hit_accession>YKL062W</Hit_accession>
  <Hit_len>630</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>4.4813e-08</Hsp_evalue>
      <Hsp_query-from>2863</Hsp_query-from>
      <Hsp_query-to>3021</Hsp_query-to>
      <Hsp_hit-from>571</Hsp_hit-from>
      <Hsp_hit-to>624</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>33</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>54</Hsp_align-len>
      <Hsp_qseq>KPFGCRECGARFATKYNLRVHERR-HTGERPFACEVCGRRFSRSYCLGRHKRCH</Hsp_qseq>
      <Hsp_hseq>KPFKCKDCEKAFRRSEHLKRHIRSVHSTERPFACMFCEKKFSRSDNLSQHLKTH</Hsp_hseq>
      <Hsp_midline>KPF C++C   F    +L+ H R  H+ ERPFAC  C ++FSRS  L +H + H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YER130C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:421115:422446:-1 gene:YER130C transcript:YER130C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:COM2 description:Transcription factor that binds IME1 Upstream Activation Signal (UAS)ru; COM2 transcription is regulated by Haa1p, Sok2p and Zap1p transcriptional activators; may bind the IME1 promoter under all growth conditions to negatively regulate its transcription in the absence of a positive regulator that binds more effectively; repressor activity may depend on phosphorylation by PKA; C. albicans homolog (MNL1) plays a role in adaptation to stress [Source:SGD;Acc:S000000932]</Hit_def>
  <Hit_accession>YER130C</Hit_accession>
  <Hit_len>443</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>2.60519e-07</Hsp_evalue>
      <Hsp_query-from>2857</Hsp_query-from>
      <Hsp_query-to>3021</Hsp_query-to>
      <Hsp_hit-from>385</Hsp_hit-from>
      <Hsp_hit-to>440</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>33</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>56</Hsp_align-len>
      <Hsp_qseq>SAKPFGCRECGARFATKYNLRVHERR-HTGERPFACEVCGRRFSRSYCLGRHKRCH</Hsp_qseq>
      <Hsp_hseq>ASKQFGCEFCDRRFKRQEHLKRHVRSLHMCEKPFTCHICNKNFSRSDNLNQHVKTH</Hsp_hseq>
      <Hsp_midline>++K FGC  C  RF  + +L+ H R  H  E+PF C +C + FSRS  L +H + H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YML081W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:104777:108532:1 gene:YML081W transcript:YML081W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TDA9 description:Transcription factor that regulates acetate production; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; TDA9 has a paralog, RSF2, that arose from the whole genome duplication [Source:SGD;Acc:S000004546]</Hit_def>
  <Hit_accession>YML081W</Hit_accession>
  <Hit_len>1251</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>6.58657e-07</Hsp_evalue>
      <Hsp_query-from>2863</Hsp_query-from>
      <Hsp_query-to>3012</Hsp_query-to>
      <Hsp_hit-from>59</Hsp_hit-from>
      <Hsp_hit-to>108</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>30</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>50</Hsp_align-len>
      <Hsp_qseq>KPFGCRECGARFATKYNLRVHERRHTGERPFACEVCGRRFSRSYCLGRHK</Hsp_qseq>
      <Hsp_hseq>RPFLCHICTRGFVRQEHLKRHQRAHTNEKPFLCVFCGRCFARRDLVLRHQ</Hsp_hseq>
      <Hsp_midline>+PF C  C   F  + +L+ H+R HT E+PF C  CGR F+R   + RH+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YDR216W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:895035:899006:1 gene:YDR216W transcript:YDR216W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ADR1 description:Carbon source-responsive zinc-finger transcription factor; required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization [Source:SGD;Acc:S000002624]</Hit_def>
  <Hit_accession>YDR216W</Hit_accession>
  <Hit_len>1323</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>2.10475e-06</Hsp_evalue>
      <Hsp_query-from>2845</Hsp_query-from>
      <Hsp_query-to>3015</Hsp_query-to>
      <Hsp_hit-from>96</Hsp_hit-from>
      <Hsp_hit-to>152</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>31</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>57</Hsp_align-len>
      <Hsp_qseq>SPHSSAKPFGCRECGARFATKYNLRVHERRHTGERPFACEVCGRRFSRSYCLGRHKR</Hsp_qseq>
      <Hsp_hseq>TPSGKLRSFVCEVCTRAFARQEHLKRHYRSHTNEKPYPCGLCNRCFTRRDLLIRHAQ</Hsp_hseq>
      <Hsp_midline>+P    + F C  C   FA + +L+ H R HT E+P+ C +C R F+R   L RH +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YGL254W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:22304:23203:1 gene:YGL254W transcript:YGL254W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FZF1 description:Transcription factor involved in sulfite metabolism; sole identified regulatory target is SSU1; overexpression suppresses sulfite-sensitivity of many unrelated mutants due to hyperactivation of SSU1, contains five zinc fingers; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003223]</Hit_def>
  <Hit_accession>YGL254W</Hit_accession>
  <Hit_len>299</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>4.87424e-06</Hsp_evalue>
      <Hsp_query-from>2851</Hsp_query-from>
      <Hsp_query-to>3021</Hsp_query-to>
      <Hsp_hit-from>36</Hsp_hit-from>
      <Hsp_hit-to>94</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>34</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>59</Hsp_align-len>
      <Hsp_qseq>HSSAKPFGCRE--CGARFATKYNLRVHERRHTGERPFACEVCGRRFSRSYCLGRHKRCH</Hsp_qseq>
      <Hsp_hseq>HTNQKPYHCDEPGCGKKFIRPCHLRVHKWTHSQIKPKACTLCQKRFVTNQQLRRHLNSH</Hsp_hseq>
      <Hsp_midline>H++ KP+ C E  CG +F    +LRVH+  H+  +P AC +C +RF  +  L RH   H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>2095638309</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053965-RA transcript Note:&quot;Similar to Mycbpap MYCBP-associated protein (Mus musculus)&quot; offset:0 AED:0.58 eAED:0.66 QI:0|0.3|0.36|0.54|1|1|11|0|391</Iteration_query-def>
  <Iteration_query-len>1176</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>92</Statistics_hsp-len>
      <Statistics_eff-space>692060100</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0042666-RA transcript Note:&quot;Similar to MPRIP Myosin phosphatase Rho-interacting protein (Homo sapiens)&quot; offset:1677 AED:1.00 eAED:1.00 QI:1677|0|0|0|0.53|0.56|16|241|527</Iteration_query-def>
  <Iteration_query-len>3502</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2405089489</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0042667-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.33|0.28|7|1|333</Iteration_query-def>
  <Iteration_query-len>1000</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>563776281</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053968-RA transcript Note:&quot;Protein of unknown function&quot; offset:252 AED:0.41 eAED:0.41 QI:252|0.5|0.42|0.71|0.66|0.57|7|0|498</Iteration_query-def>
  <Iteration_query-len>1749</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1116088696</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053973-RA transcript Note:&quot;Similar to Gga1 ADP-ribosylation factor-binding protein GGA1 (Mus musculus)&quot; offset:20 AED:0.08 eAED:0.08 QI:20|0.64|0.73|1|0.92|0.86|15|3578|603</Iteration_query-def>
  <Iteration_query-len>5410</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>104</Statistics_hsp-len>
      <Statistics_eff-space>3784806233</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053974-RA transcript Note:&quot;Similar to Abca3 ATP-binding cassette sub-family A member 3 (Mus musculus)&quot; offset:0 AED:0.19 eAED:0.19 QI:0|0.2|0.27|1|1|1|11|4202|640</Iteration_query-def>
  <Iteration_query-len>6125</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YOL075C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:189658:193542:-1 gene:YOL075C transcript:YOL075C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Putative ABC transporter [Source:SGD;Acc:S000005435]</Hit_def>
  <Hit_accession>YOL075C</Hit_accession>
  <Hit_len>1294</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.8626</Hsp_bit-score>
      <Hsp_score>172</Hsp_score>
      <Hsp_evalue>2.25889e-12</Hsp_evalue>
      <Hsp_query-from>1090</Hsp_query-from>
      <Hsp_query-to>1554</Hsp_query-to>
      <Hsp_hit-from>52</Hsp_hit-from>
      <Hsp_hit-to>231</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>188</Hsp_align-len>
      <Hsp_qseq>IPAGECFGLLGFNGAGKTTTFKMLTGEETATSGDAVIGGYSILTDIRKVQQRIG---------------------------YCPQFDGLLEHMTGRETLWMYARLR-GVPERLIPAMVDDALRALLVEAYADKLV-----RTYSGGTKRKLSTAVALMGSPPVVFLDEPSTGMDPVARRLLMEECEAL</Hsp_qseq>
      <Hsp_hseq>LPSGSVMAVMGGSGSGKTTLLNVLASK--------ISGGLTHNGSIRYVLEDTGSEPNETEPKRAHLDGQDHPIQKHVIMAYLPQQDVLSPRLTCRETLKFAADLKLNSSERTKKLMVEQLIEELGLKDCADTLVGDNSHRGLSGGEKRRLSIGTQMISNPSIMFLDEPTTGLDAYSAFLVIKTLKKL</Hsp_hseq>
      <Hsp_midline>+P+G    ++G +G+GKTT   +L  +        + GG +    IR V +  G                           Y PQ D L   +T RETL   A L+    ER    MV+  +  L ++  AD LV     R  SGG KR+LS    ++ +P ++FLDEP+TG+D  +  L+++  + L</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>7.3598e-10</Hsp_evalue>
      <Hsp_query-from>1111</Hsp_query-from>
      <Hsp_query-to>1557</Hsp_query-to>
      <Hsp_hit-from>724</Hsp_hit-from>
      <Hsp_hit-to>885</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>162</Hsp_align-len>
      <Hsp_qseq>GLLGFNGAGKTTTFKMLTGE-ETATSGDAVIGGYSILTDIR----KVQQRIGYCPQFDG-LLEHMTGRETLWMYA--RLRGVPERLIPAMVDDALRALLVE-----AYADKLVRTYSGGTKRKLSTAVALMGSPPVVFLDEPSTGMDPVARRLLMEECEALC</Hsp_qseq>
      <Hsp_hseq>AIMGPSGSGKSSLLNLISGRLKSSVFAKFDTSGSIMFNDIQVSELMFKNVCSYVSQDDDHLLAALTVKETLKYAAALRLHHLTEAERMERTDNLIRSLGLKHCENNIIGNEFVKGISGGEKRRVTMGVQLLNDPPILLLDEPTSGLDSFTSATILEILEKLC</Hsp_hseq>
      <Hsp_midline> ++G +G+GK++   +++G  +++        G  +  DI+      +    Y  Q D  LL  +T +ETL   A  RL  + E       D+ +R+L ++        ++ V+  SGG KR+++  V L+  PP++ LDEP++G+D      ++E  E LC</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YIL013C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:328207:332442:-1 gene:YIL013C transcript:YIL013C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PDR11 description:ATP-binding cassette (ABC) transporter; multidrug transporter involved in multiple drug resistance; mediates sterol uptake when sterol biosynthesis is compromised; regulated by Pdr1p; required for anaerobic growth; PDR11 has a paralog, AUS1, that arose from the whole genome duplication [Source:SGD;Acc:S000001275]</Hit_def>
  <Hit_accession>YIL013C</Hit_accession>
  <Hit_len>1411</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>4.10572e-12</Hsp_evalue>
      <Hsp_query-from>1066</Hsp_query-from>
      <Hsp_query-to>1560</Hsp_query-to>
      <Hsp_hit-from>764</Hsp_hit-from>
      <Hsp_hit-to>933</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>176</Hsp_align-len>
      <Hsp_qseq>RLCRNLVGIPAGECFGLLGFNGAGKTTTFKMLT--GEETATSGDAVIGGYSILTDIRKVQQRIGYCPQFDGLLEHMTGRETLWMYARLRGVPERLIPAMVDDALRALLVEAYADKLVRTYSGGTKRKLSTAVALMGSPP-VVFLDEPSTGMDPVA--------RRLLMEECEALCT</Hsp_qseq>
      <Hsp_hseq>KLINDASGYISSGLTALMGESGAGKTTLLNVLSQRTESGVVTGELLIDGQP-LTNIDAFRRSIGFVQQQDVHLELLTVRESLEISCVLRGDGDRDYLGVVSNLLRLP-----SEKLVADLSPTQRKLLSIGVELVTKPSLLLFLDEPTSGLDAEAALTIVQFLKKLSMQGQAILCT</Hsp_hseq>
      <Hsp_midline>+L  +  G  +     L+G +GAGKTT   +L+   E    +G+ +I G   LT+I   ++ IG+  Q D  LE +T RE+L +   LRG  +R    +V + LR       ++KLV   S   ++ LS  V L+  P  ++FLDEP++G+D  A        ++L M+    LCT</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YOR153W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:619840:624375:1 gene:YOR153W transcript:YOR153W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PDR5 description:Plasma membrane ATP-binding cassette (ABC) transporter; multidrug transporter actively regulated by Pdr1p; also involved in steroid transport, cation resistance, and cellular detoxification during exponential growth; PDR5 has a paralog, PDR15, that arose from the whole genome duplication [Source:SGD;Acc:S000005679]</Hit_def>
  <Hit_accession>YOR153W</Hit_accession>
  <Hit_len>1511</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>1.47804e-11</Hsp_evalue>
      <Hsp_query-from>1066</Hsp_query-from>
      <Hsp_query-to>1512</Hsp_query-to>
      <Hsp_hit-from>886</Hsp_hit-from>
      <Hsp_hit-to>1042</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>RLCRNLVG-IPAGECFGLLGFNGAGKTTTFKMLTGEET--ATSGDAVIGGYSILTDIRKVQQRIGYCPQFDGLLEHMTGRETLWMYARLRGVPERLIPAM---VDDALRALLVEAYADKLVRTYSGG----TKRKLSTAVALMGSPP-VVFLDEPSTGMD</Hsp_qseq>
      <Hsp_hseq>RILNNVDGWVKPGTLTALMGASGAGKTTLLDCLAERVTMGVITGDILVNG---IPRDKSFPRSIGYCQQQDLHLKTATVRESLRFSAYLRQPAEVSIEEKNRYVEEVIKILEMEKYADAVVGVAGEGLNVEQRKRLTIGVELTAKPKLLVFLDEPTSGLD</Hsp_hseq>
      <Hsp_midline>R+  N+ G +  G    L+G +GAGKTT    L    T    +GD ++ G   +   +   + IGYC Q D  L+  T RE+L   A LR   E  I      V++ ++ L +E YAD +V     G     +++L+  V L   P  +VFLDEP++G+D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YDR011W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:465919:470424:1 gene:YDR011W transcript:YDR011W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNQ2 description:Plasma membrane ATP-binding cassette (ABC) transporter; multidrug transporter involved in multidrug resistance and resistance to singlet oxygen species [Source:SGD;Acc:S000002418]</Hit_def>
  <Hit_accession>YDR011W</Hit_accession>
  <Hit_len>1501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>4.5639e-11</Hsp_evalue>
      <Hsp_query-from>1069</Hsp_query-from>
      <Hsp_query-to>1512</Hsp_query-to>
      <Hsp_hit-from>871</Hsp_hit-from>
      <Hsp_hit-to>1025</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>159</Hsp_align-len>
      <Hsp_qseq>LCRNLVG--IPAGECFGLLGFNGAGKTTTFKMLTGEETAT-SGDAVIGGYSILTDIRKVQQRIGYCPQFDGLLEHMTGRETLWMYARLR---GVPERLIPAMVDDALRALLVEAYADKLVRTYSGG----TKRKLSTAVALMGSPP-VVFLDEPSTGMD</Hsp_qseq>
      <Hsp_hseq>LLDNVSGYCIP-GTMTALMGESGAGKTTLLNTLAQRNVGIITGDMLVNGRPIDASF---ERRTGYVQQQDIHIAELTVRESLQFSARMRRPQHLPDSEKMDYVEKIIRVLGMEEYAEALVGEVGCGLNVEQRKKLSIGVELVAKPDLLLFLDEPTSGLD</Hsp_hseq>
      <Hsp_midline>L  N+ G  IP G    L+G +GAGKTT    L        +GD ++ G  I       ++R GY  Q D  +  +T RE+L   AR+R    +P+      V+  +R L +E YA+ LV     G     ++KLS  V L+  P  ++FLDEP++G+D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YNR070W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:765375:769376:1 gene:YNR070W transcript:YNR070W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PDR18 description:Putative transporter of the ATP-binding cassette (ABC) family; role in plasma membrane sterol incorporation; implicated in pleiotropic drug resistance; provides resistance to ethanol stress and contributes to a decreased intracellular accumulation of ethanol; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [Source:SGD;Acc:S000005353]</Hit_def>
  <Hit_accession>YNR070W</Hit_accession>
  <Hit_len>1333</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>1.78291e-10</Hsp_evalue>
      <Hsp_query-from>1075</Hsp_query-from>
      <Hsp_query-to>1560</Hsp_query-to>
      <Hsp_hit-from>745</Hsp_hit-from>
      <Hsp_hit-to>925</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>184</Hsp_align-len>
      <Hsp_qseq>RNLVGIPAGECF-----GLLGFNGAGKTTTFKMLTGEETAT-SGDAVIGGYSILTDIRKVQQRIGYCPQFDGLLEHMTGRETLWMYARLR---GVPERLIPAMVDDALRALLVEAYADKLVRTYSGG----TKRKLSTAVALMGSPP-VVFLDEPSTGMD--------PVARRLLMEECEALCT</Hsp_qseq>
      <Hsp_hseq>RKLLDSVSGYCVPGTLTALIGESGAGKTTLLNTLAQRNVGTITGDMLVDGLPMDASFKR---RTGYVQQQDLHVAELTVKESLQFSARMRRPQSIPDAEKMEYVEKIISILEMQEFSEALVGEIGYGLNVEQRKKLSIGVELVGKPDLLLFLDEPTSGLDSQSAWAVVKMLKRLALAGQSILCT</Hsp_hseq>
      <Hsp_midline>R L+   +G C       L+G +GAGKTT    L      T +GD ++ G  +    ++   R GY  Q D  +  +T +E+L   AR+R    +P+      V+  +  L ++ +++ LV     G     ++KLS  V L+G P  ++FLDEP++G+D         + +RL +     LCT</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YCR011C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:133724:136873:-1 gene:YCR011C transcript:YCR011C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ADP1 description:Putative ATP-dependent permease of the ABC transporter family [Source:SGD;Acc:S000000604]</Hit_def>
  <Hit_accession>YCR011C</Hit_accession>
  <Hit_len>1049</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>2.23531e-10</Hsp_evalue>
      <Hsp_query-from>1090</Hsp_query-from>
      <Hsp_query-to>1512</Hsp_query-to>
      <Hsp_hit-from>413</Hsp_hit-from>
      <Hsp_hit-to>561</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>152</Hsp_align-len>
      <Hsp_qseq>IPAGECFGLLGFNGAGKTTTFKMLTGEETA--TSGDAVIGGYSILTDIRKVQQRIGYCPQFDGLLEHMTGRETLWMYARLRGVPERLI----PAMVDDALRALLVEAY-----ADKLVRTYSGGTKRKLSTAVALMGSPPVVFLDEPSTGMD</Hsp_qseq>
      <Hsp_hseq>VKPGQILAIMGGSGAGKTTLLDILAMKRKTGHVSGSIKVNGISM--DRKSFSKIIGFVDQDDFLLPTLTVFETVLNSALLR-LPKALSFEAKKARVYKVLEELRIIDIKDRIIGNEFDRGISGGEKRRVSIACELVTSPLVLFLDEPTSGLD</Hsp_hseq>
      <Hsp_midline>+  G+   ++G +GAGKTT   +L  +      SG   + G S+  D +   + IG+  Q D LL  +T  ET+   A LR +P+ L      A V   L  L +         ++  R  SGG KR++S A  L+ SP V+FLDEP++G+D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YOR011W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:349679:353863:1 gene:YOR011W transcript:YOR011W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AUS1 description:Plasma membrane sterol transporter of the ATP-binding cassette family; required, along with Pdr11p, for uptake of exogenous sterols and their incorporation into the plasma membrane; activity is stimulated by phosphatidylserine; sterol uptake is required for anaerobic growth because sterol biosynthesis requires oxygen; AUS1 has a paralog, PDR11, that arose from the whole genome duplication [Source:SGD;Acc:S000005537]</Hit_def>
  <Hit_accession>YOR011W</Hit_accession>
  <Hit_len>1394</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>4.1869e-10</Hsp_evalue>
      <Hsp_query-from>1066</Hsp_query-from>
      <Hsp_query-to>1521</Hsp_query-to>
      <Hsp_hit-from>764</Hsp_hit-from>
      <Hsp_hit-to>912</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>155</Hsp_align-len>
      <Hsp_qseq>RLCRNLVGIPAGECFGLLGFNGAGKTTTFKMLTG--EETATSGDAVIGGYSILTDIRKVQQRIGYCPQFDGLLEHMTGRETLWMYARLRGVPERLIPAMVDDALRALLVEAYADKLVRTYSGGTKRKLSTAVALMGSPP-VVFLDEPSTGMDPVA</Hsp_qseq>
      <Hsp_hseq>KLINNASGFISSGLTALMGESGAGKTTLLNVLSQRVETGVVSGEILIDGHP-LTDEDAFKRSIGFVQQQDLHLDLLSVKESLEISCLLRGDGDRAYLDTVSN-----LLKLPSDILVADLNPTQRKLLSIGVELVTKPSLLLFLDEPTSGLDAEA</Hsp_hseq>
      <Hsp_midline>+L  N  G  +     L+G +GAGKTT   +L+   E    SG+ +I G+  LTD    ++ IG+  Q D  L+ ++ +E+L +   LRG  +R     V +     L++  +D LV   +   ++ LS  V L+  P  ++FLDEP++G+D  A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YOR328W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:931803:936497:1 gene:YOR328W transcript:YOR328W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PDR10 description:ATP-binding cassette (ABC) transporter; multidrug transporter involved in the pleiotropic drug resistance network; regulated by Pdr1p and Pdr3p [Source:SGD;Acc:S000005855]</Hit_def>
  <Hit_accession>YOR328W</Hit_accession>
  <Hit_len>1564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>1.34892e-09</Hsp_evalue>
      <Hsp_query-from>1066</Hsp_query-from>
      <Hsp_query-to>1512</Hsp_query-to>
      <Hsp_hit-from>940</Hsp_hit-from>
      <Hsp_hit-to>1096</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>RLCRNLVG-IPAGECFGLLGFNGAGKTTTFKMLTGEETA--TSGDAVIGGYSILTDIRKVQQRIGYCPQFDGLLEHMTGRETLWMYARLRGVPERLIP---AMVDDALRALLVEAYADKLVRTYSGG----TKRKLSTAVALMGSPP-VVFLDEPSTGMD</Hsp_qseq>
      <Hsp_hseq>RILDNVDGWVKPGTLTALIGASGAGKTTLLDCLAERTTMGLITGDVFVDGRP---RDQSFPRSIGYCQQQDLHLKTATVRESLRFSAYLRQADDVSIEEKDKYVEEVIEVLEMKLYADAIVGVPGEGLNVEQRKRLTIGVELAAKPKLLVFLDEPTSGLD</Hsp_hseq>
      <Hsp_midline>R+  N+ G +  G    L+G +GAGKTT    L    T    +GD  + G       +   + IGYC Q D  L+  T RE+L   A LR   +  I      V++ +  L ++ YAD +V     G     +++L+  V L   P  +VFLDEP++G+D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YDR406W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1279210:1283799:1 gene:YDR406W transcript:YDR406W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PDR15 description:Plasma membrane ATP binding cassette (ABC) transporter; multidrug transporter and general stress response factor implicated in cellular detoxification; regulated by Pdr1p, Pdr3p and Pdr8p; promoter contains a PDR responsive element; PDR15 has a paralog, PDR5, that arose from the whole genome duplication [Source:SGD;Acc:S000002814]</Hit_def>
  <Hit_accession>YDR406W</Hit_accession>
  <Hit_len>1529</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>4.22228e-09</Hsp_evalue>
      <Hsp_query-from>1066</Hsp_query-from>
      <Hsp_query-to>1560</Hsp_query-to>
      <Hsp_hit-from>901</Hsp_hit-from>
      <Hsp_hit-to>1081</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>186</Hsp_align-len>
      <Hsp_qseq>RLCRNLVG-IPAGECFGLLGFNGAGKTTTFKMLTGEETATSGDAVIGGYSILTDIR----KVQQRIGYCPQFDGLLEHMTGRETLWMYARLRGVPERLIPAM---VDDALRALLVEAYADKLVRTYSGG----TKRKLSTAVALMGSPP-VVFLDEPSTGMDP--------VARRLLMEECEALCT</Hsp_qseq>
      <Hsp_hseq>RILNNVDGWVKPGTLTALMGASGAGKTTLLDCLA--ERVTMG--VITG-NIFVDGRLRDESFPRSIGYCQQQDLHLKTATVRESLRFSAYLRQPSSVSIEEKNRYVEEVIKILEMQQYSDAVVGVAGEGLNVEQRKRLTIGVELAARPKLLVFLDEPTSGLDSQTAWDTCQLMRKLATHGQAILCT</Hsp_hseq>
      <Hsp_midline>R+  N+ G +  G    L+G +GAGKTT    L   E  T G  VI G +I  D R       + IGYC Q D  L+  T RE+L   A LR      I      V++ ++ L ++ Y+D +V     G     +++L+  V L   P  +VFLDEP++G+D         + R+L       LCT</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YPL058C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:445842:450377:-1 gene:YPL058C transcript:YPL058C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PDR12 description:Plasma membrane ATP-binding cassette (ABC) transporter; weak-acid-inducible multidrug transporter required for weak organic acid resistance; induced by sorbate and benzoate and regulated by War1p; mutants exhibit sorbate hypersensitivity [Source:SGD;Acc:S000005979]</Hit_def>
  <Hit_accession>YPL058C</Hit_accession>
  <Hit_len>1511</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>6.67326e-08</Hsp_evalue>
      <Hsp_query-from>1066</Hsp_query-from>
      <Hsp_query-to>1512</Hsp_query-to>
      <Hsp_hit-from>859</Hsp_hit-from>
      <Hsp_hit-to>1015</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>RLCRNLVG-IPAGECFGLLGFNGAGKTTTFKMLTGEET--ATSGDAVIGGYSILTDIRKVQQRIGYCPQFDGLLEHMTGRETLWMYARLR---GVPERLIPAMVDDALRALLVEAYADKLV----RTYSGGTKRKLSTAVALMGSPP-VVFLDEPSTGMD</Hsp_qseq>
      <Hsp_hseq>KLLSDVFGYVKPGKMTALMGESGAGKTTLLNVLAQRINMGVITGDMLVNAKPLPASFNR---SCGYVAQADNHMAELSVRESLRFAAELRQQSSVPLEEKYEYVEKIITLLGMQNYAEALVGKTGRGLNVEQRKKLSIGVELVAKPSLLLFLDEPTSGLD</Hsp_hseq>
      <Hsp_midline>+L  ++ G +  G+   L+G +GAGKTT   +L         +GD ++    +     +     GY  Q D  +  ++ RE+L   A LR    VP       V+  +  L ++ YA+ LV    R  +   ++KLS  V L+  P  ++FLDEP++G+D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YMR301C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:867555:869627:-1 gene:YMR301C transcript:YMR301C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATM1 description:Mitochondrial inner membrane ATP-binding cassette (ABC) transporter; exports mitochondrially synthesized precursors of iron-sulfur (Fe/S) clusters to the cytosol; human homolog ABCB7 can complement yeast null mutant [Source:SGD;Acc:S000004916]</Hit_def>
  <Hit_accession>YMR301C</Hit_accession>
  <Hit_len>690</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>8.95783e-08</Hsp_evalue>
      <Hsp_query-from>1090</Hsp_query-from>
      <Hsp_query-to>1668</Hsp_query-to>
      <Hsp_hit-from>459</Hsp_hit-from>
      <Hsp_hit-to>676</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>IPAGECFGLLGFNGAGKTTTFKMLTGEETATSGDAVIGGYSILT-DIRKVQQRIGYCPQFDGLLEHMTGRETLW---MYARLRGVPERLIPAMVDDALRALLVEAYA---DKLV----RTYSGGTKRKLSTAVALMGSPPVVFLDEPSTGMDPVARRLLMEECE--------------------ALCTRIAIMVNGQFRCLGSQQHLKSRYGSGYTLLARIRAE</Hsp_qseq>
      <Hsp_hseq>IPAGWKTAIVGSSGSGKSTILKLVFRFYDPESGRILINGRDIKEYDIDALRKVIGVVPQDTPLFN-----DTIWENVKFGRIDATDEEVI-TVVEKAQLAPLIKKLPQGFDTIVGERGLMISGGEKQRLAIARVLLKNARIMFFDEATSALDTHTEQALLRTIRDNFTSGSRTSVYIAHRLRTIADADKIIVLDNGRVREEGKHLELLAMPGSLYRELWTIQED</Hsp_hseq>
      <Hsp_midline>IPAG    ++G +G+GK+T  K++       SG  +I G  I   DI  +++ IG  PQ   L       +T+W    + R+    E +I  +V+ A  A L++      D +V       SGG K++L+ A  L+ +  ++F DE ++ +D    + L+                        A   +I ++ NG+ R  G    L +  GS Y  L  I+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>105</Statistics_hsp-len>
      <Statistics_eff-space>4299985712</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053975-RA transcript Note:&quot;Similar to Abca3 ATP-binding cassette sub-family A member 3 (Mus musculus)&quot; offset:0 AED:0.47 eAED:0.47 QI:0|0|0|0.86|0.92|0.93|15|0|818</Iteration_query-def>
  <Iteration_query-len>2457</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDR011W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:465919:470424:1 gene:YDR011W transcript:YDR011W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNQ2 description:Plasma membrane ATP-binding cassette (ABC) transporter; multidrug transporter involved in multidrug resistance and resistance to singlet oxygen species [Source:SGD;Acc:S000002418]</Hit_def>
  <Hit_accession>YDR011W</Hit_accession>
  <Hit_len>1501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>2.28351e-09</Hsp_evalue>
      <Hsp_query-from>1747</Hsp_query-from>
      <Hsp_query-to>2127</Hsp_query-to>
      <Hsp_hit-from>882</Hsp_hit-from>
      <Hsp_hit-to>1064</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>62</Hsp_gaps>
      <Hsp_align-len>186</Hsp_align-len>
      <Hsp_qseq>GQITALLGHNGAGKTTTLSILTGPG-----GTALVNGYDIRYDMTLVRKSLGLCPQHDVLFPDLTVEEHLSFFAKLK----------------------------------GCPYE--------------RVPDEVVLLDEPTSGMDPCARRATWELLQR-QRAGRTVLLTTH-----FMEEADVL</Hsp_qseq>
      <Hsp_hseq>GTMTALMGESGAGKTTLLNTLAQRNVGIITGDMLVNGRPI--DASFERRT-GYVQQQDIHIAELTVRESLQFSARMRRPQHLPDSEKMDYVEKIIRVLGMEEYAEALVGEVGCGLNVEQRKKLSIGVELVAKPDLLLFLDEPTSGLDSQSSWAIIQLLRKLSKAGQSILCTIHQPSATLFEEFDRL</Hsp_hseq>
      <Hsp_midline>G +TAL+G +GAGKTT L+ L         G  LVNG  I  D +  R++ G   Q D+   +LTV E L F A+++                                  GC                   PD ++ LDEPTSG+D  +  A  +LL++  +AG+++L T H       EE D L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1634699507</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053976-RA transcript Note:&quot;Similar to Ccnf Cyclin-F (Rattus norvegicus)&quot; offset:227 AED:0.38 eAED:0.38 QI:227|0.75|0.70|1|0.87|0.88|17|0|568</Iteration_query-def>
  <Iteration_query-len>1934</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YLR210W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:562008:563390:1 gene:YLR210W transcript:YLR210W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLB4 description:B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the G2/M transition; may be involved in DNA replication and spindle assembly; accumulates during S phase and G2, then targeted for ubiquitin-mediated degradation; CLB4 has a paralog, CLB3, that arose from the whole genome duplication [Source:SGD;Acc:S000004200]</Hit_def>
  <Hit_accession>YLR210W</Hit_accession>
  <Hit_len>460</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.2705</Hsp_bit-score>
      <Hsp_score>212</Hsp_score>
      <Hsp_evalue>2.58166e-18</Hsp_evalue>
      <Hsp_query-from>1035</Hsp_query-from>
      <Hsp_query-to>1598</Hsp_query-to>
      <Hsp_hit-from>239</Hsp_hit-from>
      <Hsp_hit-to>425</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>189</Hsp_align-len>
      <Hsp_qseq>MRYLLIDWLAEVVTTKELSSACLHTTVQCLDRYLLQRPVERSKLQLLGIACMVICSRFLSQDILTIREGVWLTDNTYKYEDMVRMMGEIISVLRGRIVAPMVLEYVRVLLALEPLDARASCTLSYVCELSLLFTSVTAYSPAHLAASAFLLTR-ILHRHAVLWSKKLVDFTGFLLEDLIPCTLLLHKQC</Hsp_qseq>
      <Hsp_hseq>FRRTMIDWLVQLHFRFQLLPETLYLTINIVDRFLSKKTVTLNRFQLVGVSALFIAAKFEEINCPTLDDLVYMLENTYTRDDIIRAEQYMIDTLEFEIGWPGPMPFLRRISKADDYDFEPRTLAKYLLETTIVEPKLVAAAPSWLAAGAYFLSRTILGSND--WSLKHVFYSGYTSSQIIPLASLILENC</Hsp_hseq>
      <Hsp_midline> R  +IDWL ++    +L    L+ T+  +DR+L ++ V  ++ QL+G++ + I ++F   +  T+ + V++ +NTY  +D++R    +I  L   I  P  + ++R +   +  D        Y+ E +++   + A +P+ LAA A+ L+R IL  +   WS K V ++G+    +IP   L+ + C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YDL155W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:176773:178056:1 gene:YDL155W transcript:YDL155W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLB3 description:B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the G2/M transition; may be involved in DNA replication and spindle assembly; accumulates during S phase and G2, then targeted for ubiquitin-mediated degradation; relative distribution to the nucleus increases upon DNA replication stress; CLB3 has a paralog, CLB4, that arose from the whole genome duplication [Source:SGD;Acc:S000002314]</Hit_def>
  <Hit_accession>YDL155W</Hit_accession>
  <Hit_len>427</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.7146</Hsp_bit-score>
      <Hsp_score>182</Hsp_score>
      <Hsp_evalue>9.27661e-15</Hsp_evalue>
      <Hsp_query-from>1014</Hsp_query-from>
      <Hsp_query-to>1598</Hsp_query-to>
      <Hsp_hit-from>193</Hsp_hit-from>
      <Hsp_hit-to>386</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>195</Hsp_align-len>
      <Hsp_qseq>QKGMNENMRYLLIDWLAEVVTTKELSSACLHTTVQCLDRYLLQRPVERSKLQLLGIACMVICSRFLSQDILTIREGVWLTDNTYKYEDMVRMMGEIISVLRGRIVAPMVLEYVRVLLALEPLDARASCTLSYVCELSLLFTSVTAYSPAHLAASAFLLTRILHRHAVLWSKKLVDFTGFLLEDLIPCTLLLHKQC</Hsp_qseq>
      <Hsp_hseq>QPELRWSFRSTLIDWIVQVHEKFQLLPETLYLCINIIDRYLCKEVVPVNKFQLVGAASLFIAAKYEEINCPTIKDFVYMSENCYSRNDLLDAERTILNGLEFELGWPGPMSFLRRISKADDYEHDTRTLAKYLLESTIMDHRLVSAQPSWLAAGAYFLSKIILGQNQ-WSLAHVYYSNYTQEQILPLATIILENC</Hsp_hseq>
      <Hsp_midline>Q  +  + R  LIDW+ +V    +L    L+  +  +DRYL +  V  +K QL+G A + I +++   +  TI++ V++++N Y   D++     I++ L   +  P  + ++R +   +  +        Y+ E +++   + +  P+ LAA A+ L++I+      WS   V ++ +  E ++P   ++ + C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YGR109C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:705359:706501:-1 gene:YGR109C transcript:YGR109C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLB6 description:B-type cyclin involved in DNA replication during S phase; activates Cdc28p to promote initiation of DNA synthesis; functions in formation of mitotic spindles along with Clb3p and Clb4p; most abundant during late G1; CLB6 has a paralog, CLB5, that arose from the whole genome duplication [Source:SGD;Acc:S000003341]</Hit_def>
  <Hit_accession>YGR109C</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.3218</Hsp_bit-score>
      <Hsp_score>168</Hsp_score>
      <Hsp_evalue>4.25015e-13</Hsp_evalue>
      <Hsp_query-from>1023</Hsp_query-from>
      <Hsp_query-to>1547</Hsp_query-to>
      <Hsp_hit-from>151</Hsp_hit-from>
      <Hsp_hit-to>325</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>175</Hsp_align-len>
      <Hsp_qseq>MNENMRYLLIDWLAEVVTTKELSSACLHTTVQCLDRYLLQRPVERSKLQLLGIACMVICSRFLSQDILTIREGVWLTDNTYKYEDMVRMMGEIISVLRGRIVAPMVLEYVRVLLALEPLDARASCTLSYVCELSLLFTSVTAYSPAHLAASAFLLTRILHRHAVLWSKKLVDFTG</Hsp_qseq>
      <Hsp_hseq>LKSSMRALLIDWLVEVHEKFHCLPETLFLAINLLDRFLSQNVVKLNKLQLLCITCLFIACKFEEVKLPKITNFAYVTDGAATVEGIRKAELFVLSSLGYNISLPNPLNFIRRISKADNYCIETRNMAKFIMEYSICCNKFIHLKPSYLAAMSMYIARKIKNENSKWDETFIHYSG</Hsp_hseq>
      <Hsp_midline>+  +MR LLIDWL EV          L   +  LDR+L Q  V+ +KLQLL I C+ I  +F    +  I    ++TD     E + +    ++S L   I  P  L ++R +   +           ++ E S+         P++LAA +  + R +      W +  + ++G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YPR119W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:771653:773128:1 gene:YPR119W transcript:YPR119W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLB2 description:B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome; CLB2 has a paralog, CLB1, that arose from the whole genome duplication [Source:SGD;Acc:S000006323]</Hit_def>
  <Hit_accession>YPR119W</Hit_accession>
  <Hit_len>491</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>4.99353e-10</Hsp_evalue>
      <Hsp_query-from>1038</Hsp_query-from>
      <Hsp_query-to>1586</Hsp_query-to>
      <Hsp_hit-from>261</Hsp_hit-from>
      <Hsp_hit-to>444</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>185</Hsp_align-len>
      <Hsp_qseq>RYLLIDWLAEVVTTKELSSACLHTTVQCLDRYLLQRPVERSKLQLLGIACMVICSRFLSQDILTIREGVWLTDNTYKYEDMVRMMGEIISVLRGRIVAPMVLEYVRVLLALEPLDARASCTLSYVCELSLLFTSVTAYSPAHLAASAFLLTRILHRHAVLWSKKLVDFT-GFLLEDLIP-CTLLL</Hsp_qseq>
      <Hsp_hseq>RDILVNWLVKIHNKFGLLPETLYLAINIMDRFLGKELVQLDKLQLVGTSCLFIASKYEEVYSPSIKHFASETDGACTEDEIKEGEKFILKTLKFNLNYPNPMNFLRRISKADDYDIQSRTLAKFLLEISLVDFRFIGILPSLCAAAAMFMSRKMLGKGK-WDGNLIHYSGGYTKEELAPVCHMIM</Hsp_hseq>
      <Hsp_midline>R +L++WL ++     L    L+  +  +DR+L +  V+  KLQL+G +C+ I S++      +I+     TD     +++      I+  L+  +  P  + ++R +   +  D ++     ++ E+SL+        P+  AA+A  ++R +      W   L+ ++ G+  E+L P C +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YGR108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:703636:705051:1 gene:YGR108W transcript:YGR108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLB1 description:B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome; CLB1 has a paralog, CLB2, that arose from the whole genome duplication [Source:SGD;Acc:S000003340]</Hit_def>
  <Hit_accession>YGR108W</Hit_accession>
  <Hit_len>471</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>1.11821e-09</Hsp_evalue>
      <Hsp_query-from>984</Hsp_query-from>
      <Hsp_query-to>1586</Hsp_query-to>
      <Hsp_hit-from>226</Hsp_hit-from>
      <Hsp_hit-to>424</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>203</Hsp_align-len>
      <Hsp_qseq>PTRTHRLYRVQKGMNENMRYLLIDWLAEVVTTKELSSACLHTTVQCLDRYLLQRPVERSKLQLLGIACMVICSRFLSQDILTIREGVWLTDNTYKYEDMVRMMGEIISVLRGRIVAPMVLEYVRVLLALEPLDARASCTLSYVCELSLLFTSVTAYSPAHLAASAFLLTRILHRHAVLWSKKLVDFT-GFLLEDLIP-CTLLL</Hsp_qseq>
      <Hsp_hseq>PNKAN-LYK-HKNIKQN-RDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSRKMLGKGT-WDGNLIHYSGGYTKAKLYPVCQLLM</Hsp_hseq>
      <Hsp_midline>P + + LY+  K + +N R +L++W+ ++     L    L+  +  +DR+L +  V+ ++LQL+G +C+ I S++      +I+   + TD     ED+      I+  L  +I     + ++R +   +  D ++     ++ E+S++        P+  A++A  L+R +      W   L+ ++ G+    L P C LL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YPR120C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:773875:775182:-1 gene:YPR120C transcript:YPR120C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLB5 description:B-type cyclin involved in DNA replication during S phase; activates Cdc28p to promote initiation of DNA synthesis; functions in formation of mitotic spindles along with Clb3p and Clb4p; most abundant during late G1 phase; CLB5 has a paralog, CLB6, that arose from the whole genome duplication [Source:SGD;Acc:S000006324]</Hit_def>
  <Hit_accession>YPR120C</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>1.13501e-09</Hsp_evalue>
      <Hsp_query-from>1035</Hsp_query-from>
      <Hsp_query-to>1547</Hsp_query-to>
      <Hsp_hit-from>197</Hsp_hit-from>
      <Hsp_hit-to>369</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>173</Hsp_align-len>
      <Hsp_qseq>MRYLLIDWLAEVVTTKELSSACLHTTVQCLDRYLLQRPVERSKLQLLGIACMVICSRFLSQDILTIREGVWLTDNTYKYEDMVRMMGEIISVLRGRIVAPMVLEYVRVLLALEPLDARASCTLSYVCELSLLFTSVTAYSPAHLAASA-FLLTRILHRHAV-LWSKKLVDFTG</Hsp_qseq>
      <Hsp_hseq>MRTILVDWLVEVHEKFQCYPETLFLSINLMDRFLAKNKVTMNKLQLLAVTSLFIAAKFEEVNLPKLAEYAYITDGAASKNDIKNAEMFMLTSLEFNIGWPNPLNFLRRISKADDYDPVNRNIGKFILEYAYCCHQFIHLPPSTVSAMAMYIARRMTNRNKNELWNGTLQHYSG</Hsp_hseq>
      <Hsp_midline>MR +L+DWL EV    +     L  ++  +DR+L +  V  +KLQLL +  + I ++F   ++  + E  ++TD      D+      +++ L   I  P  L ++R +   +  D        ++ E +          P+ ++A A ++  R+ +R+   LW+  L  ++G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1249695916</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0042673-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.18 eAED:1.00 QI:0|0|0|0.5|0|0|2|0|143</Iteration_query-def>
  <Iteration_query-len>432</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>81</Statistics_hsp-len>
      <Statistics_eff-space>149906421</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053977-RA transcript Note:&quot;Similar to UBE2O (E3-independent) E2 ubiquitin-conjugating enzyme (Homo sapiens)&quot; offset:0 AED:0.38 eAED:0.38 QI:0|0.8|0.83|0.83|0.6|0.5|6|304|468</Iteration_query-def>
  <Iteration_query-len>1711</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YGL058W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:393986:394504:1 gene:YGL058W transcript:YGL058W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD6 description:Ubiquitin-conjugating enzyme (E2); involved in postreplication repair as a heterodimer with Rad18p, regulation of K63 polyubiquitination in response to oxidative stress, DSBR and checkpoint control as a heterodimer with Bre1p, ubiquitin-mediated N-end rule protein degradation as a heterodimer with Ubr1p, ERAD with Ubr1p in the absence of canonical ER membrane ligases, and Rpn4p turnover as part of proteasome homeostasis, in complex with Ubr2p and Mub1p [Source:SGD;Acc:S000003026]</Hit_def>
  <Hit_accession>YGL058W</Hit_accession>
  <Hit_len>172</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>1.52695e-14</Hsp_evalue>
      <Hsp_query-from>253</Hsp_query-from>
      <Hsp_query-to>576</Hsp_query-to>
      <Hsp_hit-from>21</Hsp_hit-from>
      <Hsp_hit-to>116</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>108</Hsp_align-len>
      <Hsp_qseq>PEGIVVKTFEDRMDLFSALIHGPARTPYEDGLFVFDIQLPAIYPACPPSFHYLSQCSGRLNPNLYENGKVCVSLLGTWVGKGTEKWTNKSSLLQVLISIQGLILVNEP</Hsp_qseq>
      <Hsp_hseq>PPGVSASPLPDNVMVWNAMIIGPADTPYEDGTFRLLLEFDEEYPNKPPHVKFLSEM---FHPNVYANGEICLDILQN-------RWTPTYDVASILTSIQSLF--NDP</Hsp_hseq>
      <Hsp_midline>P G+      D + +++A+I GPA TPYEDG F   ++    YP  PP   +LS+     +PN+Y NG++C+ +L         +WT    +  +L SIQ L   N+P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YDR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:629876:630605:1 gene:YDR092W transcript:YDR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBC13 description:E2 ubiquitin-conjugating enzyme; involved in the error-free DNA postreplication repair pathway; interacts with Mms2p to assemble ubiquitin chains at the Ub Lys-63 residue; DNA damage triggers redistribution from the cytoplasm to the nucleus [Source:SGD;Acc:S000002499]</Hit_def>
  <Hit_accession>YDR092W</Hit_accession>
  <Hit_len>153</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>9.22788e-14</Hsp_evalue>
      <Hsp_query-from>196</Hsp_query-from>
      <Hsp_query-to>654</Hsp_query-to>
      <Hsp_hit-from>5</Hsp_hit-from>
      <Hsp_hit-to>146</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>156</Hsp_align-len>
      <Hsp_qseq>PKKFFSSVRKEMALLATSLPEGIVVKTFEDRMDLFSALIHGPARTPYEDGLFVFDIQLPAIYPACPPSFHYLSQCSGRLNPNLYENGKVCVSLLGTWVGKGTEKWTNKSSLLQVLISIQGLILV---NEPYYNEAGFESDRGLQEGYENSRCYNEM</Hsp_qseq>
      <Hsp_hseq>PKRIIKETEK---LVSDPVP-GITAEPHDDNLRYFQVTIEGPEQSPYEDGIFELELYLPDDYPMEAPKVRFLTKI---YHPNIDRLGRICLDVLKT-------NWSPALQIRTVLLSIQALLASPNPNDPLANDVAEDWIKNEQGAKAKAREWTKL</Hsp_hseq>
      <Hsp_midline>PK+      K   L++  +P GI  +  +D +  F   I GP ++PYEDG+F  ++ LP  YP   P   +L++     +PN+   G++C+ +L T        W+    +  VL+SIQ L+     N+P  N+   +  +  Q     +R + ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YMR022W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:318680:319177:1 gene:YMR022W transcript:YMR022W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBC7 description:Ubiquitin conjugating enzyme; involved in the ER-associated protein degradation (ERAD) pathway and in the inner nuclear membrane-associated degradation (INMAD) pathway; requires Cue1p for recruitment to the ER membrane; proposed to be involved in chromatin assembly [Source:SGD;Acc:S000004624]</Hit_def>
  <Hit_accession>YMR022W</Hit_accession>
  <Hit_len>165</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>1.08464e-13</Hsp_evalue>
      <Hsp_query-from>223</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>11</Hsp_hit-from>
      <Hsp_hit-to>127</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>120</Hsp_align-len>
      <Hsp_qseq>KEMALLATSLPEGIVV-KTFEDRMDLFSALIHGPARTPYEDGLFVFDIQLPAIYPACPPSFHYLSQCSGRLNPNLYENGKVCVSLLGT------WVGKGTEKWTNKSSLLQVLISIQGLI</Hsp_qseq>
      <Hsp_hseq>KELQQLIKDSPPGIVAGPKSENNIFIWDCLIQGPPDTPYADGVFNAKLEFPKDYPLSPPKLTFTPSI---LHPNIYPNGEVCISILHSPGDDPNMYELAEERWSPVQSVEKILLSVMSML</Hsp_hseq>
      <Hsp_midline>KE+  L    P GIV     E+ + ++  LI GP  TPY DG+F   ++ P  YP  PP   +       L+PN+Y NG+VC+S+L +            E+W+   S+ ++L+S+  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YBR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:406628:407169:-1 gene:YBR082C transcript:YBR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBC4 description:Ubiquitin-conjugating enzyme (E2); key E2 partner with Ubc1p for the anaphase-promoting complex (APC); mediates degradation of abnormal or excess proteins, including calmodulin and histone H3; regulates levels of DNA Polymerase-{alpha} to promote efficient and accurate DNA replication; interacts with many SCF ubiquitin protein ligases; component of the cellular stress response; UBC4 has a paralog, UBC5, that arose from the whole genome duplication [Source:SGD;Acc:S000000286]</Hit_def>
  <Hit_accession>YBR082C</Hit_accession>
  <Hit_len>148</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>3.77024e-10</Hsp_evalue>
      <Hsp_query-from>217</Hsp_query-from>
      <Hsp_query-to>576</Hsp_query-to>
      <Hsp_hit-from>7</Hsp_hit-from>
      <Hsp_hit-to>116</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>120</Hsp_align-len>
      <Hsp_qseq>VRKEMALLATSLPEGIVVKTFEDRMDLFSALIHGPARTPYEDGLFVFDIQLPAIYPACPPSFHYLSQCSGRLNPNLYENGKVCVSLLGTWVGKGTEKWTNKSSLLQVLISIQGLILVNEP</Hsp_qseq>
      <Hsp_hseq>IAKELSDLERDPPTSCSAGPVGDDLYHWQASIMGPADSPYAGGVFFLSIHFPTDYPFKPPKISFTTKI---YHPNINANGNICLDIL-------KDQWSPALTLSKVLLSICSLLTDANP</Hsp_hseq>
      <Hsp_midline>+ KE++ L    P         D +  + A I GPA +PY  G+F   I  P  YP  PP   + ++     +PN+  NG +C+ +L        ++W+   +L +VL+SI  L+    P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YDR059C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:569234:569770:-1 gene:YDR059C transcript:YDR059C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBC5 description:Ubiquitin-conjugating enzyme; mediates selective degradation of short-lived, abnormal, or excess proteins, including histone H3; central component of the cellular stress response; expression is heat inducible; protein abundance increases in response to DNA replication stress; UBC5 has a paralog, UBC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002466]</Hit_def>
  <Hit_accession>YDR059C</Hit_accession>
  <Hit_len>148</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>1.62571e-09</Hsp_evalue>
      <Hsp_query-from>217</Hsp_query-from>
      <Hsp_query-to>576</Hsp_query-to>
      <Hsp_hit-from>7</Hsp_hit-from>
      <Hsp_hit-to>116</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>120</Hsp_align-len>
      <Hsp_qseq>VRKEMALLATSLPEGIVVKTFEDRMDLFSALIHGPARTPYEDGLFVFDIQLPAIYPACPPSFHYLSQCSGRLNPNLYENGKVCVSLLGTWVGKGTEKWTNKSSLLQVLISIQGLILVNEP</Hsp_qseq>
      <Hsp_hseq>IAKELSDLGRDPPASCSAGPVGDDLYHWQASIMGPSDSPYAGGVFFLSIHFPTDYPFKPPKVNFTTKI---YHPNINSSGNICLDIL-------KDQWSPALTLSKVLLSICSLLTDANP</Hsp_hseq>
      <Hsp_midline>+ KE++ L    P         D +  + A I GP+ +PY  G+F   I  P  YP  PP  ++ ++     +PN+  +G +C+ +L        ++W+   +L +VL+SI  L+    P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YDR177W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:816878:817525:1 gene:YDR177W transcript:YDR177W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBC1 description:Ubiquitin-conjugating enzyme; key E2 partner with Ubc4p for the anaphase-promoting complex (APC); mediates selective degradation of short-lived and abnormal proteins; plays a role in vesicle biogenesis and ER-associated protein degradation (ERAD); component of the cellular stress response; protein abundance increases in response to DNA replication stress key E2 partner with Ubc4p for the anaphase-promoting complex (APC) [Source:SGD;Acc:S000002584]</Hit_def>
  <Hit_accession>YDR177W</Hit_accession>
  <Hit_len>215</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>1.41273e-07</Hsp_evalue>
      <Hsp_query-from>316</Hsp_query-from>
      <Hsp_query-to>576</Hsp_query-to>
      <Hsp_hit-from>41</Hsp_hit-from>
      <Hsp_hit-to>118</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>44</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>88</Hsp_align-len>
      <Hsp_qseq>GPARTPYEDGLFVFDIQLPAIYPACPPSFHYLSQCSGRLNPNLYE-NGKVCVSLLGTWVGKGTEKWTNKSSLLQVLISIQGLILVNEP</Hsp_qseq>
      <Hsp_hseq>GPPGTPYEGGKFVVDIEVPMEYPFKPPKMQFDTKV---YHPNISSVTGAICLDILKN-------AWSPVITLKSALISLQALLQSPEP</Hsp_hseq>
      <Hsp_midline>GP  TPYE G FV DI++P  YP  PP   + ++     +PN+    G +C+ +L          W+   +L   LIS+Q L+   EP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YOR339C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:958362:958832:-1 gene:YOR339C transcript:YOR339C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBC11 description:Ubiquitin-conjugating enzyme; most similar in sequence to Xenopus ubiquitin-conjugating enzyme E2-C, but not a true functional homolog of this E2; unlike E2-C, not required for the degradation of mitotic cyclin Clb2 [Source:SGD;Acc:S000005866]</Hit_def>
  <Hit_accession>YOR339C</Hit_accession>
  <Hit_len>156</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>1.89898e-07</Hsp_evalue>
      <Hsp_query-from>217</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>13</Hsp_hit-from>
      <Hsp_hit-to>118</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>116</Hsp_align-len>
      <Hsp_qseq>VRKEMALLATSLPEGIVVKTFEDR-MDLFSALIHGPARTPYEDGLFVFDIQLPAIYPACPPSFHYLSQCSGRLNPNLYENGKVCVSLLGTWVGKGTEKWTNKSSLLQVLISIQGLI</Hsp_qseq>
      <Hsp_hseq>LQNELLQLLSSTTESISAFPVDDNDLTYWVGYITGPKDTPYSGLKFKVSLKFPQNYPFHPPMIKFLSP---MWHPNVDKSGNICLDIL-------KEKWSAVYNVETILLSLQSLL</Hsp_hseq>
      <Hsp_midline>++ E+  L +S  E I     +D  +  +   I GP  TPY    F   ++ P  YP  PP   +LS      +PN+ ++G +C+ +L        EKW+   ++  +L+S+Q L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YDL064W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:337487:338070:1 gene:YDL064W transcript:YDL064W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBC9 description:SUMO-conjugating enzyme involved in the Smt3p conjugation pathway; nuclear protein required for S- and M-phase cyclin degradation and mitotic control; involved in proteolysis mediated by the anaphase-promoting complex cyclosome (APCC) [Source:SGD;Acc:S000002222]</Hit_def>
  <Hit_accession>YDL064W</Hit_accession>
  <Hit_len>157</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.3654</Hsp_bit-score>
      <Hsp_score>111</Hsp_score>
      <Hsp_evalue>6.67531e-07</Hsp_evalue>
      <Hsp_query-from>268</Hsp_query-from>
      <Hsp_query-to>561</Hsp_query-to>
      <Hsp_hit-from>29</Hsp_hit-from>
      <Hsp_hit-to>120</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>100</Hsp_align-len>
      <Hsp_qseq>VKTFEDRMDL--FSALIHGPARTPYEDGLFVFDIQLPAIYPACPPSFHYLSQCSGRLNPNLYENGKVCVSLLGTWVGKGTEKWTNKSSLLQVLISIQGLI</Hsp_qseq>
      <Hsp_hseq>VKKADGSMDLQKWEAGIPGKEGTNWAGGVYPITVEYPNEYPSKPPKVKF---PAGFYHPNVYPSGTICLSILNE-----DQDWRPAITLKQIVLGVQDLL</Hsp_hseq>
      <Hsp_midline>VK  +  MDL  + A I G   T +  G++   ++ P  YP+ PP   +    +G  +PN+Y +G +C+S+L        + W    +L Q+++ +Q L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YER100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:359562:360314:1 gene:YER100W transcript:YER100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBC6 description:Ubiquitin-conjugating enzyme involved in ERAD; located at the cytosolic side of the ER membrane; tail region contains a transmembrane segment at the C-terminus; substrate of the ubiquitin-proteasome pathway; ER-associated protein degradation is also known as ERAD [Source:SGD;Acc:S000000902]</Hit_def>
  <Hit_accession>YER100W</Hit_accession>
  <Hit_len>250</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.3654</Hsp_bit-score>
      <Hsp_score>111</Hsp_score>
      <Hsp_evalue>2.19548e-06</Hsp_evalue>
      <Hsp_query-from>199</Hsp_query-from>
      <Hsp_query-to>474</Hsp_query-to>
      <Hsp_hit-from>4</Hsp_hit-from>
      <Hsp_hit-to>90</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>92</Hsp_align-len>
      <Hsp_qseq>KKFFSSVRKEMALLATSLPEGIVVKTFEDRMDLFSALIHGPARTPYEDGLFVFDIQLPAIYPACPPSFHYLSQCSGRLNPNLYENGKVCVSL</Hsp_qseq>
      <Hsp_hseq>KQAHKRLTKEYKLMVENPPPYILARPNEDNILEWHYIITGPADTPYKGGQYHGTLTFPSDYPYKPPAIRMIT-PNGRFKPNT----RLCLSM</Hsp_hseq>
      <Hsp_midline>K+    + KE  L+  + P  I+ +  ED +  +  +I GPA TPY+ G +   +  P+ YP  PP+   ++  +GR  PN     ++C+S+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1086356825</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0014719-RA transcript Note:&quot;Similar to Ube2o (E3-independent) E2 ubiquitin-conjugating enzyme UBE2O (Mus musculus)&quot; offset:111 AED:0.21 eAED:0.26 QI:111|0.46|0.5|0.93|0.33|0.5|16|2958|304</Iteration_query-def>
  <Iteration_query-len>3984</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YMR022W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:318680:319177:1 gene:YMR022W transcript:YMR022W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBC7 description:Ubiquitin conjugating enzyme; involved in the ER-associated protein degradation (ERAD) pathway and in the inner nuclear membrane-associated degradation (INMAD) pathway; requires Cue1p for recruitment to the ER membrane; proposed to be involved in chromatin assembly [Source:SGD;Acc:S000004624]</Hit_def>
  <Hit_accession>YMR022W</Hit_accession>
  <Hit_len>165</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>2.99976e-11</Hsp_evalue>
      <Hsp_query-from>2318</Hsp_query-from>
      <Hsp_query-to>2578</Hsp_query-to>
      <Hsp_hit-from>11</Hsp_hit-from>
      <Hsp_hit-to>95</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>88</Hsp_align-len>
      <Hsp_qseq>KEMALLATSLPEGIVVK-TFEDRMDLFSALIHGPARTPYEDGLFVFDIQLPAIYPACPPSFHYLSQCSGRLNPNLYENGKVCVSLLGT</Hsp_qseq>
      <Hsp_hseq>KELQQLIKDSPPGIVAGPKSENNIFIWDCLIQGPPDTPYADGVFNAKLEFPKDYPLSPPKLTFTPSI---LHPNIYPNGEVCISILHS</Hsp_hseq>
      <Hsp_midline>KE+  L    P GIV     E+ + ++  LI GP  TPY DG+F   ++ P  YP  PP   +       L+PN+Y NG+VC+S+L +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YGL058W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:393986:394504:1 gene:YGL058W transcript:YGL058W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD6 description:Ubiquitin-conjugating enzyme (E2); involved in postreplication repair as a heterodimer with Rad18p, regulation of K63 polyubiquitination in response to oxidative stress, DSBR and checkpoint control as a heterodimer with Bre1p, ubiquitin-mediated N-end rule protein degradation as a heterodimer with Ubr1p, ERAD with Ubr1p in the absence of canonical ER membrane ligases, and Rpn4p turnover as part of proteasome homeostasis, in complex with Ubr2p and Mub1p [Source:SGD;Acc:S000003026]</Hit_def>
  <Hit_accession>YGL058W</Hit_accession>
  <Hit_len>172</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>3.09881e-11</Hsp_evalue>
      <Hsp_query-from>2318</Hsp_query-from>
      <Hsp_query-to>2578</Hsp_query-to>
      <Hsp_hit-from>11</Hsp_hit-from>
      <Hsp_hit-to>94</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>87</Hsp_align-len>
      <Hsp_qseq>KEMALLATSLPEGIVVKTFEDRMDLFSALIHGPARTPYEDGLFVFDIQLPAIYPACPPSFHYLSQCSGRLNPNLYENGKVCVSLLGT</Hsp_qseq>
      <Hsp_hseq>RDFKRMKEDAPPGVSASPLPDNVMVWNAMIIGPADTPYEDGTFRLLLEFDEEYPNKPPHVKFLSEM---FHPNVYANGEICLDILQN</Hsp_hseq>
      <Hsp_midline>++   +    P G+      D + +++A+I GPA TPYEDG F   ++    YP  PP   +LS+     +PN+Y NG++C+ +L  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YDR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:629876:630605:1 gene:YDR092W transcript:YDR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBC13 description:E2 ubiquitin-conjugating enzyme; involved in the error-free DNA postreplication repair pathway; interacts with Mms2p to assemble ubiquitin chains at the Ub Lys-63 residue; DNA damage triggers redistribution from the cytoplasm to the nucleus [Source:SGD;Acc:S000002499]</Hit_def>
  <Hit_accession>YDR092W</Hit_accession>
  <Hit_len>153</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>3.43386e-09</Hsp_evalue>
      <Hsp_query-from>2279</Hsp_query-from>
      <Hsp_query-to>2578</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>93</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>53</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>100</Hsp_align-len>
      <Hsp_qseq>LPSDPKKFFSSVRKEMALLATSLPEGIVVKTFEDRMDLFSALIHGPARTPYEDGLFVFDIQLPAIYPACPPSFHYLSQCSGRLNPNLYENGKVCVSLLGT</Hsp_qseq>
      <Hsp_hseq>MASLPKRIIKETEK---LVSDPVP-GITAEPHDDNLRYFQVTIEGPEQSPYEDGIFELELYLPDDYPMEAPKVRFLTKI---YHPNIDRLGRICLDVLKT</Hsp_hseq>
      <Hsp_midline>+ S PK+      K   L++  +P GI  +  +D +  F   I GP ++PYEDG+F  ++ LP  YP   P   +L++     +PN+   G++C+ +L T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YBR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:406628:407169:-1 gene:YBR082C transcript:YBR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBC4 description:Ubiquitin-conjugating enzyme (E2); key E2 partner with Ubc1p for the anaphase-promoting complex (APC); mediates degradation of abnormal or excess proteins, including calmodulin and histone H3; regulates levels of DNA Polymerase-{alpha} to promote efficient and accurate DNA replication; interacts with many SCF ubiquitin protein ligases; component of the cellular stress response; UBC4 has a paralog, UBC5, that arose from the whole genome duplication [Source:SGD;Acc:S000000286]</Hit_def>
  <Hit_accession>YBR082C</Hit_accession>
  <Hit_len>148</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>2.75255e-07</Hsp_evalue>
      <Hsp_query-from>2312</Hsp_query-from>
      <Hsp_query-to>2572</Hsp_query-to>
      <Hsp_hit-from>7</Hsp_hit-from>
      <Hsp_hit-to>90</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>26</Hsp_identity>
      <Hsp_positive>41</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>87</Hsp_align-len>
      <Hsp_qseq>VRKEMALLATSLPEGIVVKTFEDRMDLFSALIHGPARTPYEDGLFVFDIQLPAIYPACPPSFHYLSQCSGRLNPNLYENGKVCVSLL</Hsp_qseq>
      <Hsp_hseq>IAKELSDLERDPPTSCSAGPVGDDLYHWQASIMGPADSPYAGGVFFLSIHFPTDYPFKPPKISFTTKI---YHPNINANGNICLDIL</Hsp_hseq>
      <Hsp_midline>+ KE++ L    P         D +  + A I GPA +PY  G+F   I  P  YP  PP   + ++     +PN+  NG +C+ +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YDR059C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:569234:569770:-1 gene:YDR059C transcript:YDR059C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UBC5 description:Ubiquitin-conjugating enzyme; mediates selective degradation of short-lived, abnormal, or excess proteins, including histone H3; central component of the cellular stress response; expression is heat inducible; protein abundance increases in response to DNA replication stress; UBC5 has a paralog, UBC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002466]</Hit_def>
  <Hit_accession>YDR059C</Hit_accession>
  <Hit_len>148</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>1.22504e-06</Hsp_evalue>
      <Hsp_query-from>2312</Hsp_query-from>
      <Hsp_query-to>2572</Hsp_query-to>
      <Hsp_hit-from>7</Hsp_hit-from>
      <Hsp_hit-to>90</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>42</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>87</Hsp_align-len>
      <Hsp_qseq>VRKEMALLATSLPEGIVVKTFEDRMDLFSALIHGPARTPYEDGLFVFDIQLPAIYPACPPSFHYLSQCSGRLNPNLYENGKVCVSLL</Hsp_qseq>
      <Hsp_hseq>IAKELSDLGRDPPASCSAGPVGDDLYHWQASIMGPSDSPYAGGVFFLSIHFPTDYPFKPPKVNFTTKI---YHPNINSSGNICLDIL</Hsp_hseq>
      <Hsp_midline>+ KE++ L    P         D +  + A I GP+ +PY  G+F   I  P  YP  PP  ++ ++     +PN+  +G +C+ +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2757642009</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053978-RA transcript Note:&quot;Similar to Pdpk1 3-phosphoinositide-dependent protein kinase 1 (Rattus norvegicus)&quot; offset:162 AED:0.04 eAED:0.04 QI:162|1|1|1|0.85|0.8|15|2658|618</Iteration_query-def>
  <Iteration_query-len>4677</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>288.886</Hsp_bit-score>
      <Hsp_score>738</Hsp_score>
      <Hsp_evalue>4.38253e-83</Hsp_evalue>
      <Hsp_query-from>445</Hsp_query-from>
      <Hsp_query-to>1311</Hsp_query-to>
      <Hsp_hit-from>116</Hsp_hit-from>
      <Hsp_hit-to>412</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>147</Hsp_identity>
      <Hsp_positive>206</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>307</Hsp_align-len>
      <Hsp_qseq>HPRKKRPEDFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFV-KLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSK-----------HARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEKFFPKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEIS------WDDLHLQTPPKLTAY</Hsp_qseq>
      <Hsp_hseq>HVVKMGIKDFKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQKLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKIQYAFTAGFPQIVKDLVKKLLVRDPNDRLTIKQ------IKAHLFFHEVNFEDGSVWDD----NPPEIQPY</Hsp_hseq>
      <Hsp_midline>H  K   +DFKFG+ LG+GS+S+VVLA    +GK+YA+K+L K ++I++KKV YV  EK  L +LN    + KLFFTFQDE  LYF L YA +G+ L  I+K+ S +E C R+Y++QI+ +++ LH++GIIHRD+KPENILL+++M +++TDFGTAKIL +              +A++ SFVGTA+YVSPELL +       D+WA GCI+YQ++AG PPF+A NEYL FQK++K++Y F   F    KDLV+KLLV DP  RL   +      +K+H FF E++      WDD     PP++  Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>286.189</Hsp_bit-score>
      <Hsp_score>731</Hsp_score>
      <Hsp_evalue>5.26188e-80</Hsp_evalue>
      <Hsp_query-from>454</Hsp_query-from>
      <Hsp_query-to>1311</Hsp_query-to>
      <Hsp_hit-from>173</Hsp_hit-from>
      <Hsp_hit-to>464</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>143</Hsp_identity>
      <Hsp_positive>207</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>298</Hsp_align-len>
      <Hsp_qseq>KKRPEDFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNH-PFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKIL--SDNSK-------HARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEKFFPKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEISWDDLHL--QTPPKLTAY</Hsp_qseq>
      <Hsp_hseq>KKGIKDFKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKVQYAFTPGFPLIIRDLVKKILVKNLDRRLTISQ------IKEHHFFKDLNFKDGSVWSKTPPEIKPY</Hsp_hseq>
      <Hsp_midline>KK  +DFKFG ++G+G++STV+LA  + T K YA K+L K ++I++KKV YV+ EK  L +LN+ P  V+LF TFQDE  LYF L YA NG+ L  ++K+ S DE C R+Y+AQI+ ++++LHS GIIHRD+KPENILL+ +M I++TDFGTAK+L  ++NS          R+ SFVGTA+YVSPELL +       D+WA GCI++Q++AG PPF+A NEYL FQK++K++Y F   F    +DLV+K+LV +  +RL   +      +K H FF ++++ D  +  +TPP++  Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>237.654</Hsp_bit-score>
      <Hsp_score>605</Hsp_score>
      <Hsp_evalue>5.06154e-65</Hsp_evalue>
      <Hsp_query-from>451</Hsp_query-from>
      <Hsp_query-to>1275</Hsp_query-to>
      <Hsp_hit-from>4</Hsp_hit-from>
      <Hsp_hit-to>300</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>131</Hsp_identity>
      <Hsp_positive>182</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>303</Hsp_align-len>
      <Hsp_qseq>RKKRPEDFKFGKILGEGSFSTVVLAKEVAT-GKEYAIKILEKRHIIKEKKVPYVNREKEVLSRL---NHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKIL--------------SDNSK-HARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEF---------PEKFFPKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEISWDD</Hsp_qseq>
      <Hsp_hseq>RKRSPHDFIFKEELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPFRGENELKTFEKIVALDYPWGPNNRINNSTSPINPLVINLVQKILVIEVNERISLEQ------IKRHPYFSKVDWND</Hsp_hseq>
      <Hsp_midline>RK+ P DF F + LG GS+STV  A +  +  K YAIK+  K+HIIKE KV YV  EK  ++ L   +H   +KL++TF DEE LYF L +A  GE+L  + K  +F++  TR ++AQ++ +LE +HS GIIHRDLKPEN+LL+ D  + ITDFG A  +              S+ SK +    SFVGTA+YVSPELL        SD+WALGC+IYQ V G PPFR  NE   F+KI+ L+Y +              P   +LV+K+LV +  +R+  ++      +K HP+FS++ W+D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>219.164</Hsp_bit-score>
      <Hsp_score>557</Hsp_score>
      <Hsp_evalue>5.37522e-63</Hsp_evalue>
      <Hsp_query-from>469</Hsp_query-from>
      <Hsp_query-to>1293</Hsp_query-to>
      <Hsp_hit-from>87</Hsp_hit-from>
      <Hsp_hit-to>358</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>109</Hsp_identity>
      <Hsp_positive>178</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>278</Hsp_align-len>
      <Hsp_qseq>DFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEKFFPKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEISWDDL---HLQTP</Hsp_qseq>
      <Hsp_hseq>DFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTY-----TLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGS-EDVKNHPWFNEVIWEKLLARYIETP</Hsp_hseq>
      <Hsp_midline>DF+  + LG GSF  V L +    G+ YA+K L+K  I+K K+V + N E+ +LS ++HPF ++++ TFQD ++++  + Y + GE+   +RK + F     +FY+A++  +LE+LHS  II+RDLKPENILL+++ HI+ITDFG AK + D +      +  GT  Y++PE+++ K   KS D W+ G +IY+++AG  PF   N    ++ I+  E +FP  F P A+DL++KL+  D  +RLG  + G    +K+HP+F+E+ W+ L   +++TP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>218.009</Hsp_bit-score>
      <Hsp_score>554</Hsp_score>
      <Hsp_evalue>7.67653e-63</Hsp_evalue>
      <Hsp_query-from>469</Hsp_query-from>
      <Hsp_query-to>1278</Hsp_query-to>
      <Hsp_hit-from>69</Hsp_hit-from>
      <Hsp_hit-to>332</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>104</Hsp_identity>
      <Hsp_positive>168</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>270</Hsp_align-len>
      <Hsp_qseq>DFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEKFFPKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEISWDDL</Hsp_qseq>
      <Hsp_hseq>DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAK-----EVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRRIGNLQSGS-RDIKAHPWFSEVVWERL</Hsp_hseq>
      <Hsp_midline>DF+  + LG GSF  V L + V  G+ YAIK+L+K+ ++K K+V + N E+ +L  + HPF ++++ TFQD   ++  + Y + GE+   +RK + F     +FY+A+++ +LE+LH+  II+RDLKPENILL+ + HI+ITDFG AK            +  GT  Y++PE++T K   KS D W+LG +IY+++AG  PF        ++KI++ +  +P  F P   DL+ KL+ +D  +R+G  + G    +K+HP+FSE+ W+ L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>214.542</Hsp_bit-score>
      <Hsp_score>545</Hsp_score>
      <Hsp_evalue>2.09573e-61</Hsp_evalue>
      <Hsp_query-from>466</Hsp_query-from>
      <Hsp_query-to>1293</Hsp_query-to>
      <Hsp_hit-from>85</Hsp_hit-from>
      <Hsp_hit-to>357</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>107</Hsp_identity>
      <Hsp_positive>175</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>279</Hsp_align-len>
      <Hsp_qseq>EDFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEKFFPKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEISWDDL---HLQTP</Hsp_qseq>
      <Hsp_hseq>QDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTY-----TLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRDLSQRLGNLQ-NGTEDVKNHPWFKEVVWEKLLSRNIETP</Hsp_hseq>
      <Hsp_midline>+DF+  + LG GSF  V L +    G+ YA+K+L+K  +++ K+V + N E+ +LS + HPF ++++ TFQD ++++  + Y + GE+   +RK + F     +FY+A++  +LE+LHS  II+RDLKPENILL+++ HI+ITDFG AK + D +      +  GT  Y++PE+++ K   KS D W+ G +IY+++AG  PF   N    ++KI+  E  FP  F    KDL+ +L+  D  QRLG  +  G   +K+HP+F E+ W+ L   +++TP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>214.927</Hsp_bit-score>
      <Hsp_score>546</Hsp_score>
      <Hsp_evalue>5.83746e-59</Hsp_evalue>
      <Hsp_query-from>448</Hsp_query-from>
      <Hsp_query-to>1296</Hsp_query-to>
      <Hsp_hit-from>333</Hsp_hit-from>
      <Hsp_hit-to>615</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>114</Hsp_identity>
      <Hsp_positive>180</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>289</Hsp_align-len>
      <Hsp_qseq>PRKKRP---EDFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKI-LSDNSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEKFFPKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEISWDDLHLQ--TPP</Hsp_qseq>
      <Hsp_hseq>PSKNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDK---TDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAAKDLLIGLLSRDPSRRLGVN---GTDEIRNHPFFKDISWKKLLLKGYIPP</Hsp_hseq>
      <Hsp_midline>P K +P   +DF   K++G+GSF  V+  ++  T K YA+K L K +I+ + +V +   E+ VL+R++ PF V L F+FQ  EKLY  L++   GE+  +++    F    +RFY A+++ +L+ LH L +I+RDLKPENILL+   HI + DFG  K+ + DN K    ++F GT +Y++PE+L  +   K+ D W LG ++Y+++ GLPP+   N  ++++KI++    FP+ F P AKDL+  LL  DP +RLG +   G   +++HPFF +ISW  L L+   PP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>214.542</Hsp_bit-score>
      <Hsp_score>545</Hsp_score>
      <Hsp_evalue>9.66633e-59</Hsp_evalue>
      <Hsp_query-from>448</Hsp_query-from>
      <Hsp_query-to>1326</Hsp_query-to>
      <Hsp_hit-from>336</Hsp_hit-from>
      <Hsp_hit-to>624</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>114</Hsp_identity>
      <Hsp_positive>188</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>299</Hsp_align-len>
      <Hsp_qseq>PRKKRP---EDFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKI-LSDNSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEKFFPKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEISWDDLHLQ--TPPKLTAYLPAMT</Hsp_qseq>
      <Hsp_hseq>PSRNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDK---TDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSRDPTRRLGYN---GADEIRNHPFFSQLSWKRLLMKGYIPP----YKPAVS</Hsp_hseq>
      <Hsp_midline>P + +P   +DF   K++G+GSF  V+  ++  T K YA+K + K +I+ + +V +   E+ VL+R++ PF V L F+FQ  EKLYF L++   GE+  +++K   FD +  RFY+A+++ +L++LH L +++RDLKPENILL+   HI + DFG  K+ + D+ K    ++F GT +Y++PELL      K+ D W LG ++Y+++ GLPP+   +   +++KI++    FP+ F   AKDL+  LL  DP +RLG +   G   +++HPFFS++SW  L ++   PP    Y PA++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>212.231</Hsp_bit-score>
      <Hsp_score>539</Hsp_score>
      <Hsp_evalue>8.2607e-57</Hsp_evalue>
      <Hsp_query-from>463</Hsp_query-from>
      <Hsp_query-to>1332</Hsp_query-to>
      <Hsp_hit-from>493</Hsp_hit-from>
      <Hsp_hit-to>799</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>118</Hsp_identity>
      <Hsp_positive>176</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>316</Hsp_align-len>
      <Hsp_qseq>PEDFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYI--RKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDF---------------GTA-------KILSDNSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFP--EKFFPKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEISWDDLHLQTPPKLTAYLPAMTED</Hsp_qseq>
      <Hsp_hseq>PQSFEKIRLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDG---FRTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKNEVSFPNNNEISRTCKDLIKKLLTKNESKRLGCKM--GAADVKKHPFFKKVQWSLLRNQEPP----LIPVLSED</Hsp_hseq>
      <Hsp_midline>P+ F+  ++LG+G    V L +E  T + YA+K+L K  +IK  K+  V  E+E+L+  NHPF V L+ +FQ E+ LY  + Y   GE  + +  RK +   E+  RFY++++ ++LE+LH LG I+RDLKPENILL++  HI ++DF               G+A       KI SD     R NSFVGT +Y++PE++       + D W LG +IY+++ G  PF+  N    F  I+K E  FP   +     KDL++KLL  +  +RLGC    G   +K HPFF ++ W  L  Q PP     +P ++ED</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>199.904</Hsp_bit-score>
      <Hsp_score>507</Hsp_score>
      <Hsp_evalue>1.24741e-53</Hsp_evalue>
      <Hsp_query-from>463</Hsp_query-from>
      <Hsp_query-to>1332</Hsp_query-to>
      <Hsp_hit-from>321</Hsp_hit-from>
      <Hsp_hit-to>624</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>108</Hsp_identity>
      <Hsp_positive>176</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>310</Hsp_align-len>
      <Hsp_qseq>PEDFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYI--RKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDF-------GTAKILSDNSKHA---------RANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFP--EKFFPKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEISWDDLHLQTPPKLTAYLPAMTED</Hsp_qseq>
      <Hsp_hseq>PQSFEKIRLLGQGDVGKVYLVRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKFPHDKEVSKNCKDLIKKLLNKNEAKRLGSK--SGAADIKRHPFFKKVQWSFLRNQDPP----LIPALNDN</Hsp_hseq>
      <Hsp_midline>P+ F+  ++LG+G    V L +E  T + +A+K+L K  +IK KK+  V  E+E+L+  +HPF V L+ +FQ ++ LY  + Y   GE  + +  RK +   E   +FY++++V++LE+LH LG I+RDLKPENILL++  H+ ++DF       G+ K    +S +          R NSFVGT +Y++PE++       + D W LG +IY+++ G  PF+  N    F  I+  + +FP  ++     KDL++KLL  +  +RLG     G   +K HPFF ++ W  L  Q PP     +PA+ ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>191.43</Hsp_bit-score>
      <Hsp_score>485</Hsp_score>
      <Hsp_evalue>2.51777e-50</Hsp_evalue>
      <Hsp_query-from>451</Hsp_query-from>
      <Hsp_query-to>1329</Hsp_query-to>
      <Hsp_hit-from>405</Hsp_hit-from>
      <Hsp_hit-to>697</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>108</Hsp_identity>
      <Hsp_positive>175</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>300</Hsp_align-len>
      <Hsp_qseq>RKKRPEDFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVL---SRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKI-LSDNSKHARANSFVGTAQYVSPELLTEKSA-CKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEKFFPK-AKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEISWDDL-HLQTPPKLTAYLPAMTE</Hsp_qseq>
      <Hsp_hseq>RHYGPQDFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKD-----RTNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNRNPKHRLGAIDDG--RELRAHPFFADIDWEALKQKKIPPPFKPHLVSETD</Hsp_hseq>
      <Hsp_midline>R   P+DF+  ++LG+G+F  V   K+  T + YA+K+L K+ I+K+ ++ +   E+ +L   +  + PF V L F+FQ    LY    Y   GE+  +++K   F E+  +FY A++V +LEHLH   I++RDLKPENILL+ + +I + DFG +K  L D     R N+F GT +Y++PELL +++   K  D W+LG +I+++  G  PF A N   ++QKI   + +FP     +  +  V+ LL  +P  RLG  + G    L++HPFF++I W+ L   + PP    +L + T+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>172.555</Hsp_bit-score>
      <Hsp_score>436</Hsp_score>
      <Hsp_evalue>7.93506e-46</Hsp_evalue>
      <Hsp_query-from>469</Hsp_query-from>
      <Hsp_query-to>1437</Hsp_query-to>
      <Hsp_hit-from>127</Hsp_hit-from>
      <Hsp_hit-to>506</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>117</Hsp_identity>
      <Hsp_positive>184</Hsp_positive>
      <Hsp_gaps>67</Hsp_gaps>
      <Hsp_align-len>385</Hsp_align-len>
      <Hsp_qseq>DFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKE--------------------------VLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARAN--------SFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEY--EFPEKFFPKAKDLVEKLLVSDPMQRLGCDE--------------------CGGYPPLKSHPFFSEISWDDLHLQTPPKLTA--YLPAMTEDDEECYGNYDDLLSGFGNMQVEET----QPIPIPSVARVP</Hsp_qseq>
      <Hsp_hseq>DFKPVRVLGQGAYGKVLLVKDVNTSKLYAMKQLRKAEILISQTATDSKREDEDKNDGNNNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIPFYLSEGMKDILNALLKKETAKRWNVDKYWAKTGANNKPTKSKKKKSGAARTSLFTEHFIFRKIDWKLLESGQLQKTTLGPIVPVIT--DLELAENFD---TEFTSMSYEETYTDSKPININSVSKSP</Hsp_hseq>
      <Hsp_midline>DFK  ++LG+G++  V+L K+V T K YA+K L K  I+  +      RE E                          +LS + HP  VKLF++F D  KLY  L Y   GE+  ++++H + DE    FY+A+I  +L  LH+ G+++RDLKPEN LLN+  H+ +TDFG +K  +++S     +        S +GT +Y +PE+L  K+  ++ D ++LGC++Y ++ G PP+   N  +I  KI + +   + P       KD++  LL  +  +R   D+                             H  F +I W  L      K T    +P +T  D E   N+D   + F +M  EET    +PI I SV++ P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>172.555</Hsp_bit-score>
      <Hsp_score>436</Hsp_score>
      <Hsp_evalue>8.80716e-44</Hsp_evalue>
      <Hsp_query-from>325</Hsp_query-from>
      <Hsp_query-to>1347</Hsp_query-to>
      <Hsp_hit-from>783</Hsp_hit-from>
      <Hsp_hit-to>1112</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>107</Hsp_identity>
      <Hsp_positive>187</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>345</Hsp_align-len>
      <Hsp_qseq>SPTADHASTSTEQXXXXXXXXXXXXXXXXXXXXXXXXXXXHPRKKRPEDFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVL---SRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEKFFPKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEISWDD-LHLQTPPKLTAYLPAMTEDDEECY</Hsp_qseq>
      <Hsp_hseq>APTSTHASRTTDQQSPQKSQTSTSAKHKKRAAKR--------RKVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQR-LSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCK--DEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRDADEVME-EPFFRNINFDDILNLRVKP---PYIPEIKSPEDTSY</Hsp_hseq>
      <Hsp_midline>+PT+ HAS +T+Q S  +   S  A   + A  +        RK   ++F   K+LG+G+F  V+L+K   T +  AIK+L+K +II+   +     EK+V    ++  HPF   L+ +FQ E ++YF + +   G+++ +++  R       +FY+A+++ +L++ H  G+I+RDLK ENILL  + HI+I D+G  K   +     R ++F GT ++++PE+L E+   K+ D WA G ++YQ++    PF   +E  +F  I+  E  +P     +   + + LL  DP +RLG         ++  PFF  I++DD L+L+  P    Y+P +   ++  Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>168.318</Hsp_bit-score>
      <Hsp_score>425</Hsp_score>
      <Hsp_evalue>5.35087e-43</Hsp_evalue>
      <Hsp_query-from>484</Hsp_query-from>
      <Hsp_query-to>1260</Hsp_query-to>
      <Hsp_hit-from>202</Hsp_hit-from>
      <Hsp_hit-to>474</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>94</Hsp_identity>
      <Hsp_positive>159</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>278</Hsp_align-len>
      <Hsp_qseq>KILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNED--MHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKS-------------SDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEY-EFPEKFF---PKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSE</Hsp_qseq>
      <Hsp_hseq>EVVGQGAFATVKKAIERTTGKTFAVKIISKRKVIGN--MDGVTRELEVLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGS---FMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGPLKDFRISEEARDFIDSLLQVDPNNRSTAAKALNHPWIKMSPLGSQ</Hsp_hseq>
      <Hsp_midline>+++G+G+F+TV  A E  TGK +A+KI+ KR +I    +  V RE EVL +LNHP  V+L   ++D E  Y  + +   G+++ ++  H +  E+  R  S QI+++++++HS+GI HRDLKP+NIL+ +D  + ++ITDFG AK+  + S      +F GT  YV+PE++  K    S              D+W++GC++Y ++ G  PF    +  ++++I +  Y E P K F    +A+D ++ LL  DP  R    +   +P +K  P  S+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>159.073</Hsp_bit-score>
      <Hsp_score>401</Hsp_score>
      <Hsp_evalue>9.8368e-43</Hsp_evalue>
      <Hsp_query-from>466</Hsp_query-from>
      <Hsp_query-to>1254</Hsp_query-to>
      <Hsp_hit-from>102</Hsp_hit-from>
      <Hsp_hit-to>362</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>95</Hsp_identity>
      <Hsp_positive>148</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>264</Hsp_align-len>
      <Hsp_qseq>EDFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEKFFPKAKDLVEKLLVSDPMQRLGCDECGGYP-PLKSHPFF</Hsp_qseq>
      <Hsp_hseq>DDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSII---NPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMPSNISQDAQDLILKLLKYDPKDRMRLGDVKMHPWILRNKPFW</Hsp_hseq>
      <Hsp_midline>+DF+ GK LG+G F  V   +  +TG   A+K++EK  IIK        RE E+ + LNHP   K +  F DE+++Y  + Y  NGEM K +R H  F++     Y  QI ++L+++H   IIHRD+KPENIL+  +  I++TDFG + I   N    R  +  GT  Y+SPE++  +    + D WALG + ++L+ G PPF    +   +++I  L+ + P      A+DL+ KLL  DP  R+   +   +P  L++ PF+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>146.747</Hsp_bit-score>
      <Hsp_score>369</Hsp_score>
      <Hsp_evalue>1.05649e-36</Hsp_evalue>
      <Hsp_query-from>469</Hsp_query-from>
      <Hsp_query-to>1218</Hsp_query-to>
      <Hsp_hit-from>54</Hsp_hit-from>
      <Hsp_hit-to>300</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>140</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>251</Hsp_align-len>
      <Hsp_qseq>DFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEK-SACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEKFFPKAKDLVEKLLVSDPMQRLGCDEC</Hsp_qseq>
      <Hsp_hseq>NYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGN-ELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGN---FLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGAAGLIKRMLIVNPLNRISIHEI</Hsp_hseq>
      <Hsp_midline>+++  K LGEGSF  V LA    TG++ A+KI+ K+ + K      + RE   L  L HP  +KL+   + ++++   + YA N E+  YI +     E   R +  QI+S++E+ H   I+HRDLKPEN+LL+E ++++I DFG + I++D +      +  G+  Y +PE+++ K  A    D+W+ G I+Y ++    PF   +  ++F+ I    Y  P+   P A  L++++L+ +P+ R+   E </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>143.665</Hsp_bit-score>
      <Hsp_score>361</Hsp_score>
      <Hsp_evalue>2.07489e-35</Hsp_evalue>
      <Hsp_query-from>454</Hsp_query-from>
      <Hsp_query-to>1233</Hsp_query-to>
      <Hsp_hit-from>76</Hsp_hit-from>
      <Hsp_hit-to>343</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>83</Hsp_identity>
      <Hsp_positive>147</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>271</Hsp_align-len>
      <Hsp_qseq>KKRPEDFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKS--SDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEK--FFPKAKDLVEKLLVSDPMQRLGCDEC-------GGYPP</Hsp_qseq>
      <Hsp_hseq>KTRGKDYHRGHFLGEGGFARCFQIKD-DSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESE--RKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRDKPISDEGKILIRDILSLDPIERPSLTEIMDYVWFRGTFPP</Hsp_hseq>
      <Hsp_midline>K R +D+  G  LGEG F+     K+  +G+ +A K + K  I  EK    +  E ++   ++HP  V+    F+D+  +Y  L    NG +++ +++ +   E   RF++ QI  +++++HS  +IHRDLK  NI  + + +++I DFG A +L++ S+  R  +  GT  Y++PE+L  K +  S   D+W+LG ++Y L+ G PPF+A +   I+++I   ++ FP       + K L+  +L  DP++R    E        G +PP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>139.428</Hsp_bit-score>
      <Hsp_score>350</Hsp_score>
      <Hsp_evalue>1.22707e-33</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>1362</Hsp_query-to>
      <Hsp_hit-from>21</Hsp_hit-from>
      <Hsp_hit-to>323</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>95</Hsp_identity>
      <Hsp_positive>157</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>314</Hsp_align-len>
      <Hsp_qseq>FKFGKILGEGSFSTVVLAKEVATGKEYAIKILEK-------RHIIKEKKVPY-VNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDE----NCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTE-KSACKSSDLWALGCIIYQLVAGLPPFRAPNEYL--IFQKIIKLEYEFPE--KFFPKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEISWDDLHLQTPPKLTAYLPAMTEDDEECYGNYDD</Hsp_qseq>
      <Hsp_hseq>WKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFR----QIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDAD---LLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIK----DSKSIKDLPRENTYLYPLADSNNHTSASIDD</Hsp_hseq>
      <Hsp_midline>+K G+ LG GS   V LA+   TG   A+K++ K        H   +  +PY + RE  ++  L+HP  + L+  ++    LY  L YA+ GE+   +  H    E    NC R    QI+  + + H+LGI+HRDLKPEN+LL+   +I+I DFG A + +D        +  G+  Y +PE+++       +SD+W+ G I++ L+ G  PF   N  +  +  K+ K ++E P   +    A+DL+ K+LV DP QR+   +   +P LK +        D   ++  P+   YL  + + +     + DD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YPR111W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:747306:749000:1 gene:YPR111W transcript:YPR111W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF20 description:Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006315]</Hit_def>
  <Hit_accession>YPR111W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>136.346</Hsp_bit-score>
      <Hsp_score>342</Hsp_score>
      <Hsp_evalue>1.32063e-33</Hsp_evalue>
      <Hsp_query-from>454</Hsp_query-from>
      <Hsp_query-to>1365</Hsp_query-to>
      <Hsp_hit-from>163</Hsp_hit-from>
      <Hsp_hit-to>500</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>96</Hsp_identity>
      <Hsp_positive>164</Hsp_positive>
      <Hsp_gaps>58</Hsp_gaps>
      <Hsp_align-len>350</Hsp_align-len>
      <Hsp_qseq>KKRPEDFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTA------------KILSDNSKHAR--------------------------ANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPF--RAPNEYLIFQKIIKLEYEFPEK------FFPKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEISWDDLHLQTPPKLTAYLPAMTEDDEECYGNYDDL</Hsp_qseq>
      <Hsp_hseq>KPKHKDFQILTQVGQGGYGQVYLAKKKDSDEICALKILNKKLLFKLNETNHVLTERDILTTTRSDWLVKLLYAFQDPESLYLAMEFVPGGDFRTLLINTRILKSGHARFYISEMFCAVNALHELGYTHRDLKPENFLIDATGHIKLTDFGLAAGTVSNERIESMKIRLEEVKNLEFPAFTERSIEDRRKIYHNMRKTEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYENLRYWKKTLRRPRTEDRRAAFSDRTWDLITR-LIADPINRV-----RSFEQVRKMSYFAEINFETLRTSSPP----FIPQL--DDETDAGYFDDF</Hsp_hseq>
      <Hsp_midline>K + +DF+    +G+G +  V LAK+  + +  A+KIL K+ + K  +  +V  E+++L+     + VKL + FQD E LY  + +   G+    +   R       RFY +++  ++  LH LG  HRDLKPEN L++   HI++TDFG A            KI  +  K+                            ANS VG+  Y++ E+L  K    + D W+LGC++++ + G  PF   + NE     +  K     P        F  +  DL+ + L++DP+ R+       +  ++   +F+EI+++ L   +PP    ++P +  DDE   G +DD </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>134.42</Hsp_bit-score>
      <Hsp_score>337</Hsp_score>
      <Hsp_evalue>2.7038e-33</Hsp_evalue>
      <Hsp_query-from>454</Hsp_query-from>
      <Hsp_query-to>1263</Hsp_query-to>
      <Hsp_hit-from>190</Hsp_hit-from>
      <Hsp_hit-to>483</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>94</Hsp_identity>
      <Hsp_positive>148</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>306</Hsp_align-len>
      <Hsp_qseq>KKRPEDF----KFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTF-----QDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNE-------------------DMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRA----PNEYLIFQKIIKLEYEFPEKFFPKAKD----LVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEI</Hsp_qseq>
      <Hsp_hseq>KTRPVSFFDKYLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGE---MQFTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVILYVCLCGFPPFSDQLGPPS---LKEQILQAKYAFYSPYWDKIDDSVLHLISNLLVLNPDERYNIDEA------LNHPWFNDI</Hsp_hseq>
      <Hsp_midline>K RP  F      GK LG G ++ V  AK   TG++ A+KI   +    +KK      E  +L R+ HP  V L  +F     + + + Y  L    +GE+ + I +     ++ ++    Q+++ L++LH   IIHRD+KPENILLN                    D+ ++I DFG AK   +       N+  GT  YV+PE+LT+K      DLW+ G I+Y  + G PPF      P+   + ++I++ +Y F   ++ K  D    L+  LLV +P +R   DE        +HP+F++I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>137.502</Hsp_bit-score>
      <Hsp_score>345</Hsp_score>
      <Hsp_evalue>4.08081e-33</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>1281</Hsp_query-to>
      <Hsp_hit-from>41</Hsp_hit-from>
      <Hsp_hit-to>331</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>95</Hsp_identity>
      <Hsp_positive>151</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>294</Hsp_align-len>
      <Hsp_qseq>FKFGKILGEGSFSTVVLA--KEVATG--------KEYAIKILEKRHIIKE-KKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDE-NCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELL--TEKSACKSSDLWALGCIIYQLVAGLPPF-RAPNE------YLIFQKIIKLEYEFPEKFFPKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEIS---WDDLH</Hsp_qseq>
      <Hsp_hseq>YILGSTLGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRKEVKIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFS-QLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVNEFC--SRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGRLYNYINSTPLKFPDYILPIPRDLLRRMLVSDPKKRINLKQIKKHEWLKPHSSFLSITPDEWDKLN</Hsp_hseq>
      <Hsp_midline>+  G  LGEG F  V L   K  +          K+ AIK++++  I  + +K   + RE   L  L+HP  VKL    Q+   +   L YA  GE  KYI+K R   E N  R +S Q++S + ++HS G++HRDLK EN+LL+++ ++ ITDFG        S++    +  G+  Y +PEL+   E    + +D+W+ G I+Y ++AG  P+   PN         ++  I     +FP+   P  +DL+ ++LVSDP +R+   +   +  LK H  F  I+   WD L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>134.035</Hsp_bit-score>
      <Hsp_score>336</Hsp_score>
      <Hsp_evalue>9.01999e-33</Hsp_evalue>
      <Hsp_query-from>454</Hsp_query-from>
      <Hsp_query-to>1371</Hsp_query-to>
      <Hsp_hit-from>171</Hsp_hit-from>
      <Hsp_hit-to>510</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>92</Hsp_identity>
      <Hsp_positive>158</Hsp_positive>
      <Hsp_gaps>58</Hsp_gaps>
      <Hsp_align-len>352</Hsp_align-len>
      <Hsp_qseq>KKRPEDFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFG-----------------------------TAKILSDNSKHAR---------ANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPE--------KFFPKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEISWDDLHLQTPPKLTAYLPAMTEDDEECYGNYDDLLS</Hsp_qseq>
      <Hsp_hseq>KPKNRDFEMITQVGQGGYGQVYLARKKDTKEVCALKILNKKLLFKLNETKHVLTERDILTTTRSEWLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINTRCLKSGHARFYISEMFCAVNALHDLGYTHRDLKPENFLIDAKGHIKLTDFGLAAGTISNERIESMKIRLEKIKDLEFPAFTEKSIEDRRKMYNQLREKEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYDNLRRWKQTLRRPRQSDGRAAFSDRTWDLITR-LIADPINRLRS-----FEHVKRMSYFADINFSTLRSMIPP----FTPQL--DSETDAGYFDDFTS</Hsp_hseq>
      <Hsp_midline>K +  DF+    +G+G +  V LA++  T +  A+KIL K+ + K  +  +V  E+++L+     + VKL + FQD + LY  + +   G+    +   R       RFY +++  ++  LH LG  HRDLKPEN L++   HI++TDFG                             T K + D  K            ANS VG+  Y++ E+L  K    + D W+LGC++++ + G  PF   +    +  + + +              F  +  DL+ + L++DP+ RL       +  +K   +F++I++  L    PP    + P +  D E   G +DD  S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>135.191</Hsp_bit-score>
      <Hsp_score>339</Hsp_score>
      <Hsp_evalue>3.17934e-32</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>1335</Hsp_query-to>
      <Hsp_hit-from>19</Hsp_hit-from>
      <Hsp_hit-to>318</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>92</Hsp_identity>
      <Hsp_positive>161</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>308</Hsp_align-len>
      <Hsp_qseq>FKFGKILGEGSFSTVVLAKEVATGKEYAIKILEK----------RHIIKEKK---VPY-VNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDEN-CTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACK-SSDLWALGCIIYQLVAGLPPFRAP--NEYLIFQKIIKLEYEFP--EKFFPKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEISWDDLHLQTPPKLTAYLPAMTEDD</Hsp_qseq>
      <Hsp_hseq>WKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFR-QIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAAL---ETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERRIKTRDILKHPLLQKYPSIR----DSKSIRGLPREDTYLTPLSESN</Hsp_hseq>
      <Hsp_midline>+K G+ LG GS   V LA+  +TG+E A+K++ K            I+       +PY + RE  ++  LNHP  ++L+  ++    LY  L YA+ GE+   + +     E+   RF+  QI+  + + H+LGI+HRDLKPEN+LL+   +I+I DFG A +    ++     +  G+  Y +PE+++       +SD+W+ G I++ L+ G  PF     N   +  K+ K E+E P  ++   +A+DL+ K+L  DP +R+   +   +P L+ +P       D   ++  P+   YL  ++E +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>129.413</Hsp_bit-score>
      <Hsp_score>324</Hsp_score>
      <Hsp_evalue>4.99797e-32</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>1200</Hsp_query-to>
      <Hsp_hit-from>37</Hsp_hit-from>
      <Hsp_hit-to>287</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>87</Hsp_identity>
      <Hsp_positive>132</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>255</Hsp_align-len>
      <Hsp_qseq>FKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEK-KVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILL---NEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEKFF--------PKAKDLVEKLLVSDPMQR</Hsp_qseq>
      <Hsp_hseq>YVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPA--GSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEY--PVKFHRPYWDSVSNKAKQFILKALNLDPSKR</Hsp_hseq>
      <Hsp_midline>+ FGK LG G+F  V  AK   TG++ A+KIL K+ +   K ++  +  E ++L RL+HP  V     F+ ++K Y     AK GE+   I K   F E        +I+S+++++HS  I+HRDLKPEN+L    +++  + + DFG AK L  + +     +  G+  YV+PE+LT+    K  D+W++G I Y L+ G   FRA        +    EY  P KF          KAK  + K L  DP +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>131.339</Hsp_bit-score>
      <Hsp_score>329</Hsp_score>
      <Hsp_evalue>2.55544e-31</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>1287</Hsp_query-to>
      <Hsp_hit-from>46</Hsp_hit-from>
      <Hsp_hit-to>332</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>89</Hsp_identity>
      <Hsp_positive>145</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>291</Hsp_align-len>
      <Hsp_qseq>FKFGKILGEGSFSTVVLAKEVATG-----KEYAIKILEKRHIIKEK-KVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFG-TAKILSDNSKHARANSFVGTAQYVSPELLTEKSA--CKSSDLWALGCIIYQLVAGLPPFRAPNE-------YLIFQKIIKLEYEFPEKFFPKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEIS---WDDLHLQ</Hsp_qseq>
      <Hsp_hseq>YIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNE---LMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARLYKYITQTPLKFPEYITPIPRDLLRRILVPNPRRRINLQTIKRHVWLKPHEAFLSIQPNYWDE-HLQ</Hsp_hseq>
      <Hsp_midline>+  G  LGEG F  V L    A+      K+ AIK++ +  I K+  K   + RE   L  L HP  + L    Q+ + +   L +   GE  KYI++ R   E+      AQ++S + ++H  G++HRDLK EN+LL++  ++ ITDFG   +   DN       +  G+  Y +PEL+    A   + +D+W+ G I+Y ++AG  P+   +E         +++ I +   +FPE   P  +DL+ ++LV +P +R+       +  LK H  F  I    WD+ HLQ</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>128.257</Hsp_bit-score>
      <Hsp_score>321</Hsp_score>
      <Hsp_evalue>4.30921e-30</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>1245</Hsp_query-to>
      <Hsp_hit-from>81</Hsp_hit-from>
      <Hsp_hit-to>372</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>87</Hsp_identity>
      <Hsp_positive>139</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>295</Hsp_align-len>
      <Hsp_qseq>FKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKR----------------------------------HIIKEKKVPY-VNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLN-EDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKS-SDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEKFFPKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSH</Hsp_qseq>
      <Hsp_hseq>WKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPN---KLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMPSNLSSEARDLISKILVIDPEKRITTQEILKHPLIKKY</Hsp_hseq>
      <Hsp_midline>+K GK LG+GS   V LAK + TG+  AIKI+ K+                                  H    +  PY + RE  ++  ++H   + LF  ++++ +LY  L Y   GE+  Y+       E     Y  QIV  + + HS  I HRDLKPEN+LL+ ++  I+I DFG A +   N       +  G+  Y SPE++  +      SD+W+ G +++ L+ G  PF   N   +  K+   +Y+ P     +A+DL+ K+LV DP +R+   E   +P +K +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>123.25</Hsp_bit-score>
      <Hsp_score>308</Hsp_score>
      <Hsp_evalue>1.39314e-29</Hsp_evalue>
      <Hsp_query-from>445</Hsp_query-from>
      <Hsp_query-to>1245</Hsp_query-to>
      <Hsp_hit-from>112</Hsp_hit-from>
      <Hsp_hit-to>417</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>91</Hsp_identity>
      <Hsp_positive>151</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>311</Hsp_align-len>
      <Hsp_qseq>HPRKKRPEDFKFGKILGEGSFSTVVLAKEVATGKE--YAIKILEKRHIIKEKKVPYVNR-----EKEVLSRL--------NHPFFVKLFFTFQDEEKLYFGLS-YAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENIL--------LNEDMH----------------IQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEKFFPK----AKDLVEKLLVSDPMQRLGCDECGGYPPLKSH</Hsp_qseq>
      <Hsp_hseq>YPEQLELHNYKLLNKIGEGAFSRVFKAVGINTDDQAPVAIKAIIKKGISSDAILKGNDRIQGSSRKKVLNEVAIHKLVSKNNPHCTK-FIAFQESANYYYLVTELVTGGEIFDRIVQLTCFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLRNNT----AKTPCGTIEYVASEVFTSKRYSMKVDMWSIGCVLFTLLCGYPPFYEKNEKTLLKKISRGDYEFLAPWWDNISSGAKNAVTHLLEVDPNKRYDIDDFLNDPWLNSY</Hsp_hseq>
      <Hsp_midline>+P +    ++K    +GEG+FS V  A  + T  +   AIK + K+ I  +  +   +R      K+VL+ +        N+P   K F  FQ+    Y+ ++     GE+   I +   F E+  R    Q+  +++H+H +GI+HRD+KPEN+L        L+ DM                 +++ DFG AK L +N+    A +  GT +YV+ E+ T K      D+W++GC+++ L+ G PPF   NE  + +KI + +YEF   ++      AK+ V  LL  DP +R   D+    P L S+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>125.946</Hsp_bit-score>
      <Hsp_score>315</Hsp_score>
      <Hsp_evalue>1.88316e-29</Hsp_evalue>
      <Hsp_query-from>469</Hsp_query-from>
      <Hsp_query-to>1200</Hsp_query-to>
      <Hsp_hit-from>119</Hsp_hit-from>
      <Hsp_hit-to>386</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>84</Hsp_identity>
      <Hsp_positive>136</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>271</Hsp_align-len>
      <Hsp_qseq>DFKFGKILGEGSFSTVVLAKEVATGKEYAIKILE---KRHIIKEKKVPYVNREKEVLSR-----------------------LNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKS-ACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEKFFPKAKDLVEKLLVSDPMQR</Hsp_qseq>
      <Hsp_hseq>DWEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPPPKNEQDVLERQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIY-DSRK--QLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKIKQGKVEYPQHLSIEVISLLSKMLVVDPKRR</Hsp_hseq>
      <Hsp_midline>D++F + +G GS   V LAK   T +  A+KI+    K  + KE+ +P    E++VL R                       L HP   +LF         Y    Y   G++L YI +H S  E+  R ++  I S+L +LH+  I+HRDLK ENI++++   I+I DFG + I  D+ K  + ++F G+  + +PELL          D+W+ G +++ LV G  PF   N  ++ +KI + + E+P+    +   L+ K+LV DP +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>125.946</Hsp_bit-score>
      <Hsp_score>315</Hsp_score>
      <Hsp_evalue>1.90016e-29</Hsp_evalue>
      <Hsp_query-from>469</Hsp_query-from>
      <Hsp_query-to>1230</Hsp_query-to>
      <Hsp_hit-from>98</Hsp_hit-from>
      <Hsp_hit-to>375</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>133</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>281</Hsp_align-len>
      <Hsp_qseq>DFKFGKILGEGSFSTVVLAKEVATGKEYAIKILE---KRHIIKEKKVPYVNREKEVLSR-----------------------LNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELL-TEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEKFFPKAKDLVEKLLVSDPMQRLGCDECGGYP</Hsp_qseq>
      <Hsp_hseq>DWEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESEILERQKRLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIF---DYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYPSHLSIEVISLLTRMIVVDPLRRATLKNVVEHP</Hsp_hseq>
      <Hsp_midline>D++F + +G GS   V L K   T +   IKI+    K ++ K+  +P    E E+L R                       L HP   +LF         Y    Y   G++L YI +H S  E+  R ++  I S+L++LH+  I+HRDLK ENI+++    I+I DFG + I        + ++F G+  + +PELL  +       D+W+ G ++Y LV G  PF   N  ++ +KI K + ++P     +   L+ +++V DP++R        +P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>124.02</Hsp_bit-score>
      <Hsp_score>310</Hsp_score>
      <Hsp_evalue>3.63825e-29</Hsp_evalue>
      <Hsp_query-from>466</Hsp_query-from>
      <Hsp_query-to>903</Hsp_query-to>
      <Hsp_hit-from>350</Hsp_hit-from>
      <Hsp_hit-to>495</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>146</Hsp_align-len>
      <Hsp_qseq>EDFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFG</Hsp_qseq>
      <Hsp_hseq>EDFHTVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFG</Hsp_hseq>
      <Hsp_midline>EDF   K++G+G+F  V L ++  TGK YA+K L K  + K+ ++ +V  E++VL+  + P+ V L+++FQD + LY  + +   G+++  + + + F E+ TRFY A+ + ++E +H LG IHRD+KP+NIL++   HI+++DFG</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>75.0998</Hsp_bit-score>
      <Hsp_score>183</Hsp_score>
      <Hsp_evalue>5.67265e-14</Hsp_evalue>
      <Hsp_query-from>928</Hsp_query-from>
      <Hsp_query-to>1308</Hsp_query-to>
      <Hsp_hit-from>563</Hsp_hit-from>
      <Hsp_hit-to>693</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>134</Hsp_align-len>
      <Hsp_qseq>SKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLE--YEFPEKFFP--KAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEISWDDL-HLQTP--PKLTA</Hsp_qseq>
      <Hsp_hseq>SRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLL-THADQRLG--RHGGADEIKSHPFFRGVDWNTIRQVEAPYIPKLSS</Hsp_hseq>
      <Hsp_midline>S+   A S VGT  Y++PE+   +   +  D W+LG I+Y+ + G PPF +      ++KI+  E   +FP+      +A+DL+ +LL +   QRLG    GG   +KSHPFF  + W+ +  ++ P  PKL++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>120.168</Hsp_bit-score>
      <Hsp_score>300</Hsp_score>
      <Hsp_evalue>5.96073e-29</Hsp_evalue>
      <Hsp_query-from>469</Hsp_query-from>
      <Hsp_query-to>1080</Hsp_query-to>
      <Hsp_hit-from>46</Hsp_hit-from>
      <Hsp_hit-to>251</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>208</Hsp_align-len>
      <Hsp_qseq>DFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEK-KVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILL---NEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRA</Hsp_qseq>
      <Hsp_hseq>NYIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLK--GEEDLIYKAAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSPFIA</Hsp_hseq>
      <Hsp_midline>++ FG+ LG GSF  V  A++++T ++ AIKIL K+ +     ++  +  E  +L +L+HP  V     F+ ++K Y     A  GE+   I     F E        QI+ ++E++HS  ++HRDLKPEN+L    +E+  + I DFG AK L    +        G+  YV+PE+LT+    K  D+W++G I Y L+ G  PF A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>116.701</Hsp_bit-score>
      <Hsp_score>291</Hsp_score>
      <Hsp_evalue>3.20944e-27</Hsp_evalue>
      <Hsp_query-from>445</Hsp_query-from>
      <Hsp_query-to>1134</Hsp_query-to>
      <Hsp_hit-from>39</Hsp_hit-from>
      <Hsp_hit-to>296</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>89</Hsp_identity>
      <Hsp_positive>138</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>261</Hsp_align-len>
      <Hsp_qseq>HPRKKRP--EDFKFGKILGEGSFSTVVLAKEVATGKEYAIKIL---EKRH---IIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEE--KLYFGLSYAKNGEMLKYIRKHR-----------SFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARA-------NSFVGTAQYVSPELL-TEKS-ACKSS-DLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFP</Hsp_qseq>
      <Hsp_hseq>NPLTKRQILNNFEILATLGNGQYGKVKLARDLGTGALVAIKILNRFEKRSGYSLQLKVENPRVNQEIEVMKRCHHENVVELYEILNDPESTKVYLVLEYCSRGPV-KWCPENKMEIKAVGPSILTFQQ--SRKVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPFNANSGLELFDSIINKPLEFP</Hsp_hseq>
      <Hsp_midline>+P  KR    +F+    LG G +  V LA+++ TG   AIKIL   EKR    +  + + P VN+E EV+ R +H   V+L+    D E  K+Y  L Y   G + K+  +++           +F +  +R     +VS LE+LHS GI HRD+KP N+L++ +  ++I+DFG A   +  S + ++       +  +GT  + +PEL  TEK  +C S+ D+W+LG  IY L+ G  PF A +   +F  II    EFP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>112.079</Hsp_bit-score>
      <Hsp_score>279</Hsp_score>
      <Hsp_evalue>4.34392e-25</Hsp_evalue>
      <Hsp_query-from>490</Hsp_query-from>
      <Hsp_query-to>1200</Hsp_query-to>
      <Hsp_hit-from>1040</Hsp_hit-from>
      <Hsp_hit-to>1298</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>126</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>259</Hsp_align-len>
      <Hsp_qseq>LGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKV-PYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAK-ILSDNSKHAR-------------ANSFVGTAQYVSPELLT---EKSACKSSDLWALGCIIYQLVAGLPPF-RAPNEYLIFQKIIKLEY-EFPEK--FFPKAKDLVEKLLVSDPMQR</Hsp_qseq>
      <Hsp_hseq>IGGGTFGQVYSAINLENGEILAVKEIKIHDTTTMKKIFPLIKEEMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEYCEGGSLASLLDHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPWSNLDNEWAIMYHVAAGRIPQLPNRDEMTAAGRAFLERCLVQDPTMR</Hsp_hseq>
      <Hsp_midline>+G G+F  V  A  +  G+  A+K ++       KK+ P +  E  VL  LNHP  V+ +      +K+   + Y + G +   +   R  DE  T+ Y+ +++  L +LH  G++HRD+KPENILL+ +  I+  DFGTA+ ++   ++  R              N  +GT  Y++PE ++    K    + D+WALGC++ ++  G  P+    NE+ I   +      + P +       +  +E+ LV DP  R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>110.923</Hsp_bit-score>
      <Hsp_score>276</Hsp_score>
      <Hsp_evalue>6.74053e-25</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>1215</Hsp_query-to>
      <Hsp_hit-from>25</Hsp_hit-from>
      <Hsp_hit-to>265</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>249</Hsp_align-len>
      <Hsp_qseq>FKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYI-RKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEKFFPKAKDLVEKLLVSDPMQRLGCDE</Hsp_qseq>
      <Hsp_hseq>YHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYEN---DEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIV-----NSSALTLAGTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNPPYHNLTDANIYYAVENDTYYPPSSFSEPLKDFLSKCFVKNMYKRPTADQ</Hsp_hseq>
      <Hsp_midline>+   +++G GS+  V  A    T +  AIK +   +   ++++  +  E  +L  LNH   VK     +   +LY  L Y  NG + + I R      EN ++ Y  Q +  L++LH  G+IHRD+K  NILL+ D  +++ DFG + I+     ++ A +  GT  +++PE+L  + A   SD+W+LG  + +++   PP+    +  I+  +    Y  P  F    KD + K  V +  +R   D+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>109.383</Hsp_bit-score>
      <Hsp_score>272</Hsp_score>
      <Hsp_evalue>2.09947e-24</Hsp_evalue>
      <Hsp_query-from>469</Hsp_query-from>
      <Hsp_query-to>1239</Hsp_query-to>
      <Hsp_hit-from>40</Hsp_hit-from>
      <Hsp_hit-to>288</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>132</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>261</Hsp_align-len>
      <Hsp_qseq>DFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDE-NCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFG-TAKILSDNSKHARANSFVGTAQYVSPELLTEKSACK-SSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEKFFP-KAKDLVEKLLVSDPMQRLGCDECGGYPPLK</Hsp_qseq>
      <Hsp_hseq>NYKILKQIGEGSFGKVYLALHRPTHRKVCLKTSDKND-------PNIVREVFYHRQFDFPYITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELF-AQISGAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTRECMTKTT----LETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDAKVIPDDARDLISRLLAKNPGERPSLSQVLRHPFLQ</Hsp_hseq>
      <Hsp_midline>++K  K +GEGSF  V LA    T ++  +K  +K         P + RE     + + P+  KL+     E K++  L Y    E+  ++   R      C   + AQI  ++ + HS+  +HRDLK ENILL+++ + ++TDFG T + ++  +      +  GT  Y++PEL+  ++      D+W+LG I+Y L+ G  PF   +E     KI+  E ++  K  P  A+DL+ +LL  +P +R    +   +P L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>108.227</Hsp_bit-score>
      <Hsp_score>269</Hsp_score>
      <Hsp_evalue>6.30061e-24</Hsp_evalue>
      <Hsp_query-from>490</Hsp_query-from>
      <Hsp_query-to>1215</Hsp_query-to>
      <Hsp_hit-from>1272</Hsp_hit-from>
      <Hsp_hit-to>1551</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>130</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>280</Hsp_align-len>
      <Hsp_qseq>LGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKV-PYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDN-------------------------SKHARAN-----SFVGTAQYVSPELLT---EKSACKSSDLWALGCIIYQLVAGLPPF-RAPNEYLIFQKIIKLEY-EFPEK--FFPKAKDLVEKLLVSDPMQRLGCDE</Hsp_qseq>
      <Hsp_hseq>IGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAALLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPWANLDNEWAIMYHVAAGHTPQFPTKDEVSSAGMKFLERCLIQNPSKRASAVE</Hsp_hseq>
      <Hsp_midline>+G G+F  V  A ++  G+  A+K +  +     +K+ P +  E  VL  LNHP  V  +      +K+   + Y + G +   +   R  DE  T+ Y+ Q++  L +LH  GI+HRD+KPENILL+ +  I+  DFG AK +++N                         SK  + N       +GT  Y++PE +T    K    + D+W+LGC++ +++ G  P+    NE+ I   +      +FP K          +E+ L+ +P +R    E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>107.457</Hsp_bit-score>
      <Hsp_score>267</Hsp_score>
      <Hsp_evalue>1.01575e-23</Hsp_evalue>
      <Hsp_query-from>481</Hsp_query-from>
      <Hsp_query-to>1251</Hsp_query-to>
      <Hsp_hit-from>1178</Hsp_hit-from>
      <Hsp_hit-to>1439</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>81</Hsp_identity>
      <Hsp_positive>136</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>273</Hsp_align-len>
      <Hsp_qseq>GKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKK-----VPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLY-FGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANS---FVGTAQYVSPELL-TEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYE--FPEKFFP----KAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPF</Hsp_qseq>
      <Hsp_hseq>GEMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQ-YLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFG----ISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANE------LLSHPF</Hsp_hseq>
      <Hsp_midline>G+++G+GSF  V L   V TG+  A+K +E      + +     V  +  E   L  L+H   V+ +  F+++  +Y   L Y   G +   IR +  FDE   +  + Q++  L +LHS GI+HRD+K +N+LL++D   +I+DFG    +S  SK   +NS     GT  +++PE++ T++      D+W+LGCI+ ++ AG  P+          KI K +     PE   P      ++ ++     +P +R   +E      L SHPF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>106.686</Hsp_bit-score>
      <Hsp_score>265</Hsp_score>
      <Hsp_evalue>1.43741e-23</Hsp_evalue>
      <Hsp_query-from>469</Hsp_query-from>
      <Hsp_query-to>1215</Hsp_query-to>
      <Hsp_hit-from>23</Hsp_hit-from>
      <Hsp_hit-to>318</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>79</Hsp_identity>
      <Hsp_positive>140</Hsp_positive>
      <Hsp_gaps>53</Hsp_gaps>
      <Hsp_align-len>299</Hsp_align-len>
      <Hsp_qseq>DFKFGKILGEGSFSTVVLAKEVATGKEY-AIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENC----TRF--------------------YSAQIVSSLEHLHSLGIIHRDLKPENILLN---------EDMH------------IQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLE--YEFPE--KFFPKAKDLVEKLLVSDPMQRLGCDE</Hsp_qseq>
      <Hsp_hseq>NYTAEKEIGKGSFATVYRGHLTSDKSQHVAIKEVSRAKLKNKKLLENLEIEIAILKKIKHPHIVGLIDCERTSTDFYLIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTS---LAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVVFEMCCGTPPFRASNHLELFKKIKRANDVITFPSYCNIEPELKELICSLLTFDPAQRIGFEE</Hsp_hseq>
      <Hsp_midline>++   K +G+GSF+TV      +   ++ AIK + +  +  +K +  +  E  +L ++ HP  V L    +     Y  + Y   G++   +++ +   EN     T F                    Y  Q+ S+L+ L S  ++HRD+KP+N+LL+         +  H            ++I DFG A+ L + S    A +  G+  Y++PE+L  +     +DLW++G +++++  G PPFRA N   +F+KI +      FP      P+ K+L+  LL  DP QR+G +E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>100.908</Hsp_bit-score>
      <Hsp_score>250</Hsp_score>
      <Hsp_evalue>1.23064e-22</Hsp_evalue>
      <Hsp_query-from>490</Hsp_query-from>
      <Hsp_query-to>1230</Hsp_query-to>
      <Hsp_hit-from>29</Hsp_hit-from>
      <Hsp_hit-to>300</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>82</Hsp_identity>
      <Hsp_positive>128</Hsp_positive>
      <Hsp_gaps>43</Hsp_gaps>
      <Hsp_align-len>281</Hsp_align-len>
      <Hsp_qseq>LGEGSFSTVVLAKEVATGKEYAIK-ILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDE-EKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPE-LLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKL----------------------------EYEFPEKFF---PKAKDLVEKLLVSDPMQRLGCDECGGYP</Hsp_qseq>
      <Hsp_hseq>VGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTY--RELKLLKHLRHENLICLQDIFLSPLEDIYFVTEL--QGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARI-----QDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENTLKFVTSLPHRDPIPFSERFKTVEPDAVDLLEKMLVFDPKKRITAADALAHP</Hsp_hseq>
      <Hsp_midline>+G G+F  V  A +  T +  AIK I++        K  Y  RE ++L  L H   + L   F    E +YF       G  L  + + R  ++   +++  QI+  L+++HS G+IHRDLKP NIL+NE+  ++I DFG A+I     +  +   +V T  Y +PE +LT +      D+W+ GCI  +++ G P F   +    F  I  L                               F E+F    P A DL+EK+LV DP +R+   +   +P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>97.8265</Hsp_bit-score>
      <Hsp_score>242</Hsp_score>
      <Hsp_evalue>6.01042e-22</Hsp_evalue>
      <Hsp_query-from>490</Hsp_query-from>
      <Hsp_query-to>1284</Hsp_query-to>
      <Hsp_hit-from>41</Hsp_hit-from>
      <Hsp_hit-to>337</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>92</Hsp_identity>
      <Hsp_positive>142</Hsp_positive>
      <Hsp_gaps>72</Hsp_gaps>
      <Hsp_align-len>317</Hsp_align-len>
      <Hsp_qseq>LGEGSFSTVVLAKEVATGKE----YAIKILEKRHIIKEKKVP----YVNREKEVLSRLNHPFFVKLFFTFQ----DEEKLYFGLSYAKNGEML-----KYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLN-EDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSS-DLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKL--------------EYEFP---------------EKFF----PKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEISWDDLHL</Hsp_qseq>
      <Hsp_hseq>IGRGAFGTVVQAYLTQDKKNWLGPFAIK-----------KVPAHTEYKSRELQILRIADHPNIVKLQYFFTHLSPQDNKVYQHLAMECLPETLQIEINRYVTNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQP---SISYICSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLREIAKLLGPPDKRFIFFSNPAYDGPLFSKPLFSGSSQQRFEKYFGHSGPDGIDLLMKILVYEPQQRLSPRR------ILAHQFFNELRNDDTFL</Hsp_hseq>
      <Hsp_midline>+G G+F TVV A      K     +AIK           KVP    Y +RE ++L   +HP  VKL + F      + K+Y  L+     E L     +Y+           R Y+ QI   + +LH LG+ HRD+KP N+L++ E   ++I DFG+AK L  N     + S++ +  Y +PEL+   +   +  D+W LGC++ +++ G   F+     L  ++I KL               Y+ P               EK+F    P   DL+ K+LV +P QRL          + +H FF+E+  DD  L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>99.3673</Hsp_bit-score>
      <Hsp_score>246</Hsp_score>
      <Hsp_evalue>6.61241e-22</Hsp_evalue>
      <Hsp_query-from>481</Hsp_query-from>
      <Hsp_query-to>1206</Hsp_query-to>
      <Hsp_hit-from>165</Hsp_hit-from>
      <Hsp_hit-to>434</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>85</Hsp_identity>
      <Hsp_positive>131</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>279</Hsp_align-len>
      <Hsp_qseq>GKILGEGSFSTVVLAKEVATGKE--------YAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEK-LYFGLSYAKNGEMLKYIRKH---RSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNED---MHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPEL-----------------LTEKSACKSSDLWALGCIIYQLVAGLPPFRAP-NEYLIFQ--KIIKLEYEFPEK--FFPKAKDLVEKLLVSDPMQRLG</Hsp_qseq>
      <Hsp_hseq>NRIVGNGTFGHVLITHNSKERDEDVCYHPENYAVKIIK----LKPNKF---DKEARILLRLDHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDL--NSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGISPFYGDGSERSIIQNAKIGKLNFKLKQWDIVSDNAKSFVKDLLQTDVVKRLN</Hsp_hseq>
      <Hsp_midline> +I+G G+F  V++        E        YA+KI++    +K  K    ++E  +L RL+HP  +K++ TF D    LY        G++  Y+ K     S  E  +     QI+ +L +LH   I+HRDLK +NILL        I + DFG AK L  NS   R ++ VGT +Y +PE+                 L ++      DLW+LG I + ++ G+ PF    +E  I Q  KI KL ++  +       AK  V+ LL +D ++RL </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>97.8265</Hsp_bit-score>
      <Hsp_score>242</Hsp_score>
      <Hsp_evalue>7.02881e-22</Hsp_evalue>
      <Hsp_query-from>451</Hsp_query-from>
      <Hsp_query-to>1176</Hsp_query-to>
      <Hsp_hit-from>34</Hsp_hit-from>
      <Hsp_hit-to>283</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>126</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>260</Hsp_align-len>
      <Hsp_qseq>RKKRPEDFKFGKILGEGSFSTVVLAKEVATGKE----YAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRK------HRSFDENC------TRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHI-QITDFGTAKILSDNSKHARANSFVGTAQYVSPELL-TEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEKFFPKAKDLVEKL</Hsp_qseq>
      <Hsp_hseq>RQKSKMYVREGKRIGHGSFGTVTQSILSSNSIEWLGPYAIK-----RVVKSPKVQSL--ELEILQNIRHPNLVTLEFFFESHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGIAKVCDFGSAQRLDDNTE---LKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPLFKGDSANSQLEEIAKLLGRFPKSSIKNSQELQDSL</Hsp_hseq>
      <Hsp_midline>R+K     + GK +G GSF TV  +   +   E    YAIK      ++K  KV  +  E E+L  + HP  V L F F+       G    +   +++YI +      H  FD          + Y+ QI+ +L  LHS+ I H DLKP NIL+     I ++ DFG+A+ L DN++     ++  +  Y +PELL   K      D+W+LGCII +++ G P F+  +     ++I KL   FP+     +++L + L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.9005</Hsp_bit-score>
      <Hsp_score>237</Hsp_score>
      <Hsp_evalue>2.118e-21</Hsp_evalue>
      <Hsp_query-from>469</Hsp_query-from>
      <Hsp_query-to>1245</Hsp_query-to>
      <Hsp_hit-from>12</Hsp_hit-from>
      <Hsp_hit-to>312</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>141</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>305</Hsp_align-len>
      <Hsp_qseq>DFKFGKILGEGSFSTVVLAKEVATGKEYAIKILE--KRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEM---LKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKIL----SDNS----KHARANSFVGTAQYVSPE-LLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNE----YLIFQKI--------------------IKLEYEFP----EKFFPKAK----DLVEKLLVSDPMQRLGCDECGGYPPLKSH</Hsp_qseq>
      <Hsp_hseq>DFQLKSLLGEGAYGVVCSATHKPTGEIVAIKKIEPFDKPLFALRTL----REIKILKHFKHENIITIFNIQRPDSFENFNEVYIIQELMQTDLHRVISTQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHSDNDLRCIESPRAREYIKSLPMYPAAPLEKMFPRVNPKGIDLLQRMLVFDPAKRITAKEALEHPYLQTY</Hsp_hseq>
      <Hsp_midline>DF+   +LGEG++  V  A    TG+  AIK +E   + +   + +    RE ++L    H   + +F   + +    F   Y     M   L  +   +   ++  +++  Q + +++ LH   +IHRDLKP N+L+N +  +++ DFG A+I+    +DNS    + +    +V T  Y +PE +LT     ++ D+W+ GCI+ +L    P F   +      LIF  I                    IK    +P    EK FP+      DL++++LV DP +R+   E   +P L+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YFL033C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:69115:74427:-1 gene:YFL033C transcript:YFL033C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM15 description:Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase [Source:SGD;Acc:S000001861]</Hit_def>
  <Hit_accession>YFL033C</Hit_accession>
  <Hit_len>1770</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>99.3673</Hsp_bit-score>
      <Hsp_score>246</Hsp_score>
      <Hsp_evalue>3.07645e-21</Hsp_evalue>
      <Hsp_query-from>466</Hsp_query-from>
      <Hsp_query-to>912</Hsp_query-to>
      <Hsp_hit-from>792</Hsp_hit-from>
      <Hsp_hit-to>941</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>150</Hsp_align-len>
      <Hsp_qseq>EDFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLS-RLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAK</Hsp_qseq>
      <Hsp_hseq>KDYDILKPISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDKPYVARLFASFQNKDNLFLVMEYLPGGDLATLIKMMGYLPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLIDNAGHVKLTDFGLSR</Hsp_hseq>
      <Hsp_midline>+D+   K + +G++ +V LA++  TG  +AIK+L K  +I + +V  V  E+ ++  + + P+  +LF +FQ+++ L+  + Y   G++   I+      +   + Y  +IV  +  +H  GIIH DLKPEN+L++   H+++TDFG ++</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>90.1225</Hsp_bit-score>
      <Hsp_score>222</Hsp_score>
      <Hsp_evalue>2.25862e-18</Hsp_evalue>
      <Hsp_query-from>922</Hsp_query-from>
      <Hsp_query-to>1281</Hsp_query-to>
      <Hsp_hit-from>1139</Hsp_hit-from>
      <Hsp_hit-to>1263</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>130</Hsp_align-len>
      <Hsp_qseq>DNSKHARANSFVGTAQYVSPELLTEKSA-CKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPE--------KFF-PKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEISWDDLH</Hsp_qseq>
      <Hsp_hseq>DDSKQNKK--FFGTPDYLAPETIEGKGEDNKQCDWWSVGCIFFELLLGYPPFHAETPDAVFKKILSGVIQWPEFKNEEEEREFLTPEAKDLIEKLLVVDPAKRLG---AKGIQEIKDHPYFKNVDWDHVY</Hsp_hseq>
      <Hsp_midline>D+SK  +   F GT  Y++PE +  K    K  D W++GCI ++L+ G PPF A     +F+KI+    ++PE        +F  P+AKDL+EKLLV DP +RLG     G   +K HP+F  + WD ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>97.8265</Hsp_bit-score>
      <Hsp_score>242</Hsp_score>
      <Hsp_evalue>4.8127e-21</Hsp_evalue>
      <Hsp_query-from>463</Hsp_query-from>
      <Hsp_query-to>1245</Hsp_query-to>
      <Hsp_hit-from>412</Hsp_hit-from>
      <Hsp_hit-to>715</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>130</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>307</Hsp_align-len>
      <Hsp_qseq>PEDFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHI-----------------------------------------IKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSD-NSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEY----EFPEKFFPKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSH</Hsp_qseq>
      <Hsp_hseq>PKNWLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPFP---DFSQMQAIFKIGTNTTPEIPSWATSEGKNFLRKAFELDYQYRPSALELLQHPWLDAH</Hsp_hseq>
      <Hsp_midline>P+++  G  +G GSF +V L     TG+  A+K +E ++                                          I  K V  +  E  +L  L+H   V  +   Q+   L   L Y   G +   +  +  F+E+    ++ QI+  + +LH   IIHRD+K  NIL++    ++ITDFG +K LS  N K  +  S  G+  ++SPE++ + +    +D+W+ GC++ ++  G  PF    ++   Q I K+      E P     + K+ + K    D   R    E   +P L +H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.9745</Hsp_bit-score>
      <Hsp_score>232</Hsp_score>
      <Hsp_evalue>1.02102e-20</Hsp_evalue>
      <Hsp_query-from>463</Hsp_query-from>
      <Hsp_query-to>1074</Hsp_query-to>
      <Hsp_hit-from>10</Hsp_hit-from>
      <Hsp_hit-to>226</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>221</Hsp_align-len>
      <Hsp_qseq>PEDFKFGKILGEGSFSTVVLAKEVATGKEYAIKILE--------KRHIIKEKKVPYVNREKEVLSRLN--HPFFV-KLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARA-----NSFVGTAQYVSPE-LLTEKSACKSSDLWALGCIIYQLVAGLPPF</Hsp_qseq>
      <Hsp_hseq>PSQYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGF----STLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLF</Hsp_hseq>
      <Hsp_midline>P  +K   ++GEG++ TV  A    +G + AIK ++         R I + K + Y +  + ++S L+   P  + KL   +  EE +   L    N +   +     +  ++  ++++ QI+ +L+ +HS  +IHRD+KP N+LLN +  +++ DFG A+ L+ +S            +V T  Y +PE +LT +    + D+W+ GCI+ ++V+G P F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>97.4413</Hsp_bit-score>
      <Hsp_score>241</Hsp_score>
      <Hsp_evalue>1.14757e-20</Hsp_evalue>
      <Hsp_query-from>451</Hsp_query-from>
      <Hsp_query-to>1218</Hsp_query-to>
      <Hsp_hit-from>834</Hsp_hit-from>
      <Hsp_hit-to>1093</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>135</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>270</Hsp_align-len>
      <Hsp_qseq>RKKRPEDFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHI-----IKEKKVPYVNREKEVLSRLN---HPFFVKLFFTFQDEEKLYFGLSYAKNGE-----MLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKS-ACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEKFFPKAKDLVEKLLVSDPMQRLGCDEC</Hsp_qseq>
      <Hsp_hseq>RIKKFSDFTILQVMGEGAYGKVNLCIHNREHYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKNSQENILKLLDFFEDDD--YYYIETPVHGETGSIDLFDVIEFKKDMVEHEAKLVFKQVVASIKHLHDQGIVHRDIKDENVIVDSHGFVKLIDFGSAAYI----KSGPFDVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLYTIIYKENPYYNIDEILEGE----LRFDKSEHVSEECISLIKRILTREVDKRPTIDEI</Hsp_hseq>
      <Hsp_midline>R K+  DF   +++GEG++  V L           IK++ K  I     ++++K+  +  E ++++ LN       +KL   F+D++  Y+ +    +GE     +   I   +   E+  +    Q+V+S++HLH  GI+HRD+K EN++++    +++ DFG+A  +    K    + FVGT  Y +PE+L   S   K  D+WALG ++Y ++    P+   +E L  +    L ++  E    +   L++++L  +  +R   DE </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>96.2857</Hsp_bit-score>
      <Hsp_score>238</Hsp_score>
      <Hsp_evalue>2.35155e-20</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>1215</Hsp_query-to>
      <Hsp_hit-from>23</Hsp_hit-from>
      <Hsp_hit-to>269</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>119</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>252</Hsp_align-len>
      <Hsp_qseq>FKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFF-TFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSS-DLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPE--KFFPKAKDLVEKLLVSDPMQRLGCDE</Hsp_qseq>
      <Hsp_hseq>FKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDE--VEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLRPGK-IDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQV--NQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIKSKPPRLEDRSYSTSLKEFIALCLDEDPKERLSADD</Hsp_hseq>
      <Hsp_midline>FK  +++G G F  V     V TG+ YAIK+L       E  V  V RE + L+ L     +  ++ ++  +  L+  + +   G +   +R  +  DE        +++ +L+ +H   +IHRD+K  N+L+  + ++++ DFG A  +  N    R  +  GT  +++PE++ E     +  D+W+LG   Y++  G PP+         Q IIK +    E   +    K+ +   L  DP +RL  D+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.1301</Hsp_bit-score>
      <Hsp_score>235</Hsp_score>
      <Hsp_evalue>6.02271e-20</Hsp_evalue>
      <Hsp_query-from>451</Hsp_query-from>
      <Hsp_query-to>1284</Hsp_query-to>
      <Hsp_hit-from>126</Hsp_hit-from>
      <Hsp_hit-to>455</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>96</Hsp_identity>
      <Hsp_positive>157</Hsp_positive>
      <Hsp_gaps>74</Hsp_gaps>
      <Hsp_align-len>341</Hsp_align-len>
      <Hsp_qseq>RKKRPEDFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRH--------IIKEKKVP---YVNREKEVLSRLNHPFFVKLFFTFQD--EEKLYFGLSYAKNGEM-------LKYIRKH---RSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTA--------KILSDNSKHARANSFVGTAQYVSPEL-----------LTEKSACKSS------DLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFP---------------EKFFPKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEISWDDLHL</Hsp_qseq>
      <Hsp_hseq>KRKVLNTYEIIKELGHGQHGKVKLARDILSKQLVAIKIVDRHEKKQRKFFTFIKSSKISENDKIKREIAIMKKCHHKHVVQLIEVLDDLKSRKIYLVLEYCSRGEVKWCPPDCMESDAKGPSLLSFQE--TREILRGVVLGLEYLHYQGIIHRDIKPANLLISGDGTVKISDFGVSLAASSTNSSDSSESLDELELAKTVGTPAFFAPEMCLGEDAFTRYNLTKENLFRGSCISFMIDIWAVGVTLYCLLFGMLPFFSDFELKLFEKIVNDPLKFPTFKEIQSNKVSKVSCEEEYEMAKDLLLKLLEKNPQKRMTI------PAIKKHPF---VSWDFDHV</Hsp_hseq>
      <Hsp_midline>++K    ++  K LG G    V LA+++ + +  AIKI+++           IK  K+     + RE  ++ + +H   V+L     D    K+Y  L Y   GE+       ++   K     SF E  TR     +V  LE+LH  GIIHRD+KP N+L++ D  ++I+DFG +           S++         VGT  + +PE+           LT+++  + S      D+WA+G  +Y L+ G+ PF +  E  +F+KI+    +FP               E+ +  AKDL+ KLL  +P +R+        P +K HPF   +SWD  H+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.2041</Hsp_bit-score>
      <Hsp_score>230</Hsp_score>
      <Hsp_evalue>1.2226e-19</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>1242</Hsp_query-to>
      <Hsp_hit-from>163</Hsp_hit-from>
      <Hsp_hit-to>480</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>85</Hsp_identity>
      <Hsp_positive>139</Hsp_positive>
      <Hsp_gaps>71</Hsp_gaps>
      <Hsp_align-len>323</Hsp_align-len>
      <Hsp_qseq>FKFGKILGEGSFSTVVLA-------KEVATG--KEYAIKILEK----------RHIIKEKKVPYVNREKEVLSRLN-HPFF------VKLFFTFQDEEKLYFGLS-YAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILL---------------------NEDMHI-------------QITDFGTAK-ILSDNSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEKFFPK----AKDLVEKLLVSDPMQRLGCDECGGYPPLKS</Hsp_qseq>
      <Hsp_hseq>YKLINKIGEGAFSKVFRAIPAKNSSNEFLTKNYKAVAIKVIKKADLSSINGDHRKKDKGKDSTKTSSRDQVLKEVALHKTVSAGCSQIVAFIDFQETDSYYYIIQELLTGGEIFGEIVRLTYFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKNTKTP-----CGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTMLCGFPPFYDEKIDTLTEKISRGEYTFLKPWWDEISAGAKNAVAKLLELEPSKRYDIDQFLDDPWLNT</Hsp_hseq>
      <Hsp_midline>+K    +GEG+FS V  A        E  T   K  AIK+++K          R   K K     +   +VL  +  H         +  F  FQ+ +  Y+ +      GE+   I +   F E+ +R    Q+  +++H+HSLG++HRD+KPEN+L                        D  I             ++ DFG +K I S N+K        GT  Y +PE++ ++      D+W +GC++Y ++ G PPF       + +KI + EY F + ++ +    AK+ V KLL  +P +R   D+    P L +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.2041</Hsp_bit-score>
      <Hsp_score>230</Hsp_score>
      <Hsp_evalue>1.75495e-19</Hsp_evalue>
      <Hsp_query-from>490</Hsp_query-from>
      <Hsp_query-to>1074</Hsp_query-to>
      <Hsp_hit-from>626</Hsp_hit-from>
      <Hsp_hit-to>814</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>196</Hsp_align-len>
      <Hsp_qseq>LGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFG-TAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPF</Hsp_qseq>
      <Hsp_hseq>IGQGASGGVYTAYEIGTNVSVAIKQM---NLEKQPKKELIINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVT-HCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQI---NELNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPPY</Hsp_hseq>
      <Hsp_midline>+G+G+   V  A E+ T    AIK +   ++ K+ K   +  E  V+    HP  V    ++  +  L+  + Y + G +   +  H    E        + +S LE LHS G++HRD+K +NILL+ +  I++TDFG  A+I   N  + +  + VGT  +++PE+++ K      D+W+LG +I +++ G PP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.5817</Hsp_bit-score>
      <Hsp_score>218</Hsp_score>
      <Hsp_evalue>2.84697e-19</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>1089</Hsp_query-to>
      <Hsp_hit-from>7</Hsp_hit-from>
      <Hsp_hit-to>214</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>216</Hsp_align-len>
      <Hsp_qseq>FKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKH------RSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSF---VGTAQYVSPE-LLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNE</Hsp_qseq>
      <Hsp_hseq>FKQLEKLGNGTYATVYKGLNKTTGVYVALK--EVKLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDN-DLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFG-----IPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTND</Hsp_hseq>
      <Hsp_midline>FK  + LG G+++TV       TG   A+K  E +   +E       RE  ++  L H   V+L+     E KL     +  N ++ KY+         R  + N  +++  Q++  L   H   I+HRDLKP+N+L+N+   +++ DFG A+           N+F   V T  Y +P+ L+  ++   S D+W+ GCI+ +++ G P F   N+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YMR291W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:852630:854390:1 gene:YMR291W transcript:YMR291W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TDA1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000004905]</Hit_def>
  <Hit_accession>YMR291W</Hit_accession>
  <Hit_len>586</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>91.6633</Hsp_bit-score>
      <Hsp_score>226</Hsp_score>
      <Hsp_evalue>3.23223e-19</Hsp_evalue>
      <Hsp_query-from>490</Hsp_query-from>
      <Hsp_query-to>1260</Hsp_query-to>
      <Hsp_hit-from>45</Hsp_hit-from>
      <Hsp_hit-to>353</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>81</Hsp_identity>
      <Hsp_positive>133</Hsp_positive>
      <Hsp_gaps>70</Hsp_gaps>
      <Hsp_align-len>318</Hsp_align-len>
      <Hsp_qseq>LGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLN-------------------HPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFD-ENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENIL----LNED------------------MHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSS--------------DLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEKFFPKAK-----DLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSE</Hsp_qseq>
      <Hsp_hseq>LGDGNFSVVKECMNIHTKDLYAMKLIKKQTV--KNKIQLIQREFDLLRSISEKIRDMEKKNEHSLDIFEGHHHILQLFDYFETADNIVLITQLCQKGDLYEKIVENQCLDLETQVTSYCACLVSVLEFLHSQGIVHRDLKAENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLVLADFGLAAEY-NTSKVNSLKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGCPVDIWALGVLTYFMAFGYTPFDCTTDDETLECISKCDYYVDEQMMHDPKYEQFWNFVQCCFTIDPAVRRSAKN------LKQHPFIKD</Hsp_hseq>
      <Hsp_midline>LG+G+FS V     + T   YA+K+++K+ +  + K+  + RE ++L  ++                   H   ++LF  F+  + +       + G++ + I +++  D E     Y A +VS LE LHS GI+HRDLK EN+L    +NE+                    + + DFG A    + SK      FVGT  Y++PE++  K   + +              D+WALG + Y +  G  PF    +    + I K +Y   E+     K     + V+     DP  R           LK HPF  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.1225</Hsp_bit-score>
      <Hsp_score>222</Hsp_score>
      <Hsp_evalue>7.07098e-19</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>1200</Hsp_query-to>
      <Hsp_hit-from>18</Hsp_hit-from>
      <Hsp_hit-to>260</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>251</Hsp_align-len>
      <Hsp_qseq>FKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKH--RSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLT--EKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEK----FFPKAKDLVEKLLVSDPMQR</Hsp_qseq>
      <Hsp_hseq>YSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEH--SDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKR---DTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPPL---SKYDPMKVMTNLPKRKPPKLQGPFSDAAKDFVAGCLVKTPADR</Hsp_hseq>
      <Hsp_midline>+     +G G+F  V  A +  T +  AIK++   H   ++ +  + +E   L+ L  P       T  ++  ++  + Y   G     +++       E    F   ++   L++LH    IHRD+K  NILLNE+  +++ DFG +  +    K    ++FVGT  +++PE++        + +D+W+LG   Y+L+ GLPP    ++Y   + +  L    P K    F   AKD V   LV  P  R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>89.7373</Hsp_bit-score>
      <Hsp_score>221</Hsp_score>
      <Hsp_evalue>1.01474e-18</Hsp_evalue>
      <Hsp_query-from>466</Hsp_query-from>
      <Hsp_query-to>1308</Hsp_query-to>
      <Hsp_hit-from>13</Hsp_hit-from>
      <Hsp_hit-to>301</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>83</Hsp_identity>
      <Hsp_positive>148</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>303</Hsp_align-len>
      <Hsp_qseq>EDFKFGKILGEGSFSTVVLAK-EVATGKEYAIKILEKRHIIKEKKVPYVNRE--KEVLSRLN---HPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLH-SLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARAN-SFVGTAQYVSPELL--TEKSACKSSDLWALGCIIYQLVAGLPPFRAP---NEYLIFQKIIKLEYEFPEKFFPKAK------DLVEKLLVSDPMQRLGCDECGGYPPLKSHPFF---SEISWDDLHLQTPPKLTA</Hsp_qseq>
      <Hsp_hseq>KDVVLGDTVGQGAFACVKNAHLQMDPSIILAVKFI---HVPTCKKMGLSDKDITKEVVLQSKCSKHPNVLRLIDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQTPWELPSLENEDFVF----FIENDGNLNWGPWSKIEFTHLNLLRKILQPDPNKRV------TLKALKLHPWVLRRASFSGDD-GLCNDPELLA</Hsp_hseq>
      <Hsp_midline>+D   G  +G+G+F+ V  A  ++      A+K +   H+   KK+   +++  KEV+ +     HP  ++L      +E ++  L  A  G++   I      D +  +FY  Q+VS++ +LH   G+ HRD+KPENILL+++ ++++ DFG A          R +    G+  Y++PE+L   E      +D+W++G +++ L+ G  P+  P   NE  +F     +E +    + P +K      +L+ K+L  DP +R+          LK HP+    +  S DD  L   P+L A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>89.3521</Hsp_bit-score>
      <Hsp_score>220</Hsp_score>
      <Hsp_evalue>1.27983e-18</Hsp_evalue>
      <Hsp_query-from>487</Hsp_query-from>
      <Hsp_query-to>1245</Hsp_query-to>
      <Hsp_hit-from>226</Hsp_hit-from>
      <Hsp_hit-to>491</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>272</Hsp_align-len>
      <Hsp_qseq>ILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEK--LYFGLSYAKNGEMLKYIRKHR-----SFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQ------------LVAGLPPFRAPNEYLIFQKIIKLEYEFPEKFFPKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSH</Hsp_qseq>
      <Hsp_hseq>ILGEGAGGSVSKCKLKNGSKIFALKVINTLNTDPEYQ-KQIFRELQFNRSFQSEYIVRYYGMFTDDENSSIYIAMEYM-GGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFG----VSGEAVNSLATTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANGKFPCSSEKMAANIAPFELLMWILTFTPELKDEPESNIIWSPSFKSFIDYCLKKDSRERPSPRQMINHPWIKGQ</Hsp_hseq>
      <Hsp_midline>ILGEG+  +V   K     K +A+K++   +   E +   + RE +        + V+ +  F D+E   +Y  + Y   G  L  I K+         E      +  ++  L +LH   +IHRD+KP+NILLNE+  +++ DFG    +S  + ++ A +F GT+ Y++PE +  +    +SD+W+LG  I +            + A + PF      L F   +K E E    + P  K  ++  L  D  +R    +   +P +K  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.0409</Hsp_bit-score>
      <Hsp_score>214</Hsp_score>
      <Hsp_evalue>2.02997e-18</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>1275</Hsp_query-to>
      <Hsp_hit-from>39</Hsp_hit-from>
      <Hsp_hit-to>329</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>81</Hsp_identity>
      <Hsp_positive>141</Hsp_positive>
      <Hsp_gaps>59</Hsp_gaps>
      <Hsp_align-len>309</Hsp_align-len>
      <Hsp_qseq>FKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTF-----QDEEKLYFGLSYAKNG---EMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLG-IIHRDLKPENILLN-EDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLT-EKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQ--KIIK-----------------LEYEFPE-------KFFPKAKD----LVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEISWDD</Hsp_qseq>
      <Hsp_hseq>FPTTEVVGHGSFGVVFATVIQETNEKVAIK-----KVLQDKR--FKNRELEIMKMLSHINIIDLKYFFYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNV---SYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMF--PGESGIDQLVEIIKILGTPSKQEICSMNPNYMEHKFPQIKPIPLSRVFKKEDDQTVEFLADVLKYDPLERFNALQC------LCSPYFDELKLDD</Hsp_hseq>
      <Hsp_midline>F   +++G GSF  V       T ++ AIK      ++++K+  + NRE E++  L+H   + L + F     QDE  L   L Y        +  ++ +         ++Y  Q+  SL +LH    + HRD+KP+N+L++ E   +++ DFG+AK L     +    S++ +  Y +PEL+    +     D+W+ GC++ +L+ G P F  P E  I Q  +IIK                 +E++FP+       + F K  D     +  +L  DP++R    +C         P+F E+  DD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>89.7373</Hsp_bit-score>
      <Hsp_score>221</Hsp_score>
      <Hsp_evalue>2.89644e-18</Hsp_evalue>
      <Hsp_query-from>457</Hsp_query-from>
      <Hsp_query-to>1095</Hsp_query-to>
      <Hsp_hit-from>1091</Hsp_hit-from>
      <Hsp_hit-to>1311</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>114</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>227</Hsp_align-len>
      <Hsp_qseq>KRPEDFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHI-----IKEKKVPYVNREKEVLSRLN---HPFFVKLFFTFQDEEKLYFGLSYAKNGE-----MLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELL-TEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYL</Hsp_qseq>
      <Hsp_hseq>KKFSDFVSLQKMGEGAYGKVNLCIHKKNRYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKKPHENILRLLDFFEDDD--YYYIETPVHGETGCIDLFDLIEFKTNMTEFEAKLIFKQVVAGIKHLHDQGIVHRDIKDENVIVDSKGFVKIIDFGSAAYV----KSGPFDVFVGTIDYAAPEVLGGNPYEGQPQDIWAIGILLYTVVFKENPFYNIDEIL</Hsp_hseq>
      <Hsp_midline>K+  DF   + +GEG++  V L           IK++ K  I     ++++K+  +  E ++++ LN   H   ++L   F+D++  Y+ +    +GE     +   I    +  E   +    Q+V+ ++HLH  GI+HRD+K EN++++    ++I DFG+A  +    K    + FVGT  Y +PE+L       +  D+WA+G ++Y +V    PF   +E L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.4261</Hsp_bit-score>
      <Hsp_score>215</Hsp_score>
      <Hsp_evalue>4.56425e-18</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>1236</Hsp_query-to>
      <Hsp_hit-from>23</Hsp_hit-from>
      <Hsp_hit-to>318</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>132</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>298</Hsp_align-len>
      <Hsp_qseq>FKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYF------GLSYAKN---GEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDN--SKHARANSFVGTAQYVSPE-LLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKL------------------EYEFPEKFFPK-------------AKDLVEKLLVSDPMQRLGCDECGGYPPL</Hsp_qseq>
      <Hsp_hseq>FQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFS--KTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPYL</Hsp_hseq>
      <Hsp_midline>F+  K +G G++  V  A+     ++  + I +  ++    K     R    L  L H    K      D + +++      GL   +     +M + I+  +   +   + ++ QI+  L+++HS  ++HRDLKP N+L+N D  ++I DFG A+  S+N          +V T  Y +PE +L+ +   K+ D+W+ GCI+ + + G P F+  +      +I+++                  +Y     F PK             A DL+E++L  DP +R+  DE   +P L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.5741</Hsp_bit-score>
      <Hsp_score>205</Hsp_score>
      <Hsp_evalue>1.20683e-17</Hsp_evalue>
      <Hsp_query-from>490</Hsp_query-from>
      <Hsp_query-to>1260</Hsp_query-to>
      <Hsp_hit-from>14</Hsp_hit-from>
      <Hsp_hit-to>297</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>130</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>293</Hsp_align-len>
      <Hsp_qseq>LGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKK-VPYVN-REKEVLSRLNHPFFVKLF-FTFQDEEKLYFGLSYAKNGEMLKY---IRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPE-LLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKL-----EYEFPEKFF------------------------PKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSE</Hsp_qseq>
      <Hsp_hseq>VGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFL-DLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLR-AYTHEIV-TLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIVYLPDFKPSFPQWRRKDLSQVVPSLDPRGIDLLDKLLAYDPINRISARRAA------IHPYFQE</Hsp_hseq>
      <Hsp_midline>+GEG++  V  A ++  G+   +  L+K  +  E + VP    RE  +L  L     V+L+     D  KLY    +  + ++ +Y   I K +    +  + +  Q+   + + HS  I+HRDLKP+N+L+N+D ++++ DFG A+      + A  +  V T  Y +PE LL  K      D W++GCI  ++    P F   +E     KI ++     E  +P+  +                        P+  DL++KLL  DP+ R+             HP+F E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.1149</Hsp_bit-score>
      <Hsp_score>209</Hsp_score>
      <Hsp_evalue>5.40304e-17</Hsp_evalue>
      <Hsp_query-from>487</Hsp_query-from>
      <Hsp_query-to>1113</Hsp_query-to>
      <Hsp_hit-from>374</Hsp_hit-from>
      <Hsp_hit-to>583</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>219</Hsp_align-len>
      <Hsp_qseq>ILGEGSFSTVVLAKEVATGKEYAIKILEKR-----HIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNG--EMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLN--EDMHIQITDFGTAKILSDNSKHARA-NSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKII</Hsp_qseq>
      <Hsp_hseq>ILGQGTFGQVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILELLNQK--IDPTNKHHFLRMYDSFVHKNHLCLVFELLSNNLYELLKQNKFH-GLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPELKIIDFGSS------CEEARTVYTYIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAELFLGIPIFPGASEYNQLTRII</Hsp_hseq>
      <Hsp_midline>ILG+G+F  VV  + + T +  A+K+++ R       I E K+  +  +K  +   N   F++++ +F  +  L        N   E+LK  + H        R ++ QI+ SL  L    +IH DLKPENILL   +   ++I DFG++       + AR   +++ +  Y +PE++       S D+W+LGCI+ +L  G+P F   +EY    +II</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YDL079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:312951:314748:-1 gene:YDL079C transcript:YDL079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRK1 description:Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication [Source:SGD;Acc:S000002237]</Hit_def>
  <Hit_accession>YDL079C</Hit_accession>
  <Hit_len>501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.9593</Hsp_bit-score>
      <Hsp_score>206</Hsp_score>
      <Hsp_evalue>5.59402e-17</Hsp_evalue>
      <Hsp_query-from>484</Hsp_query-from>
      <Hsp_query-to>1119</Hsp_query-to>
      <Hsp_hit-from>168</Hsp_hit-from>
      <Hsp_hit-to>380</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>KILGEGSFSTVVLAKEVATGKEYAIK-ILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTF-----QDEEKLYFGLSYAKNG---EMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSL-GIIHRDLKPENILLN-EDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELL-TEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKL</Hsp_qseq>
      <Hsp_hseq>EVVGHGSFGVVVTTVIIETNQKVAIKKVLQDRR--------YKNRELETMKMLCHPNTVGLQYYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNV---SYICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKI</Hsp_hseq>
      <Hsp_midline>+++G GSF  VV    + T ++ AIK +L+ R         Y NRE E +  L HP  V L + F     +DE  L   L Y        +  ++           +FY+ Q+  +L +LH++  I HRD+KP+N+L++      +I DFG+AK L  +  +    S++ +  Y +PEL+    +     D+W+  C+I +L+ G P F   +      +IIK+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.5741</Hsp_bit-score>
      <Hsp_score>205</Hsp_score>
      <Hsp_evalue>9.25913e-17</Hsp_evalue>
      <Hsp_query-from>487</Hsp_query-from>
      <Hsp_query-to>1161</Hsp_query-to>
      <Hsp_hit-from>219</Hsp_hit-from>
      <Hsp_hit-to>442</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>233</Hsp_align-len>
      <Hsp_qseq>ILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEK--LYFGLSYAKNGEMLK-----YIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLE-YEFPEKFFPKAKD</Hsp_qseq>
      <Hsp_hseq>ILGEGAGGSVAKCRLKNGKKVFALKTINTMNTDPEYQ-KQIFRELQFNKSFKSDYIVQYYGMFTDEQSSSIYIAMEYM-GGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFG----VSGEAVNSLAMTFTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRFPFESDK---ITQNVAPIELLTMILTFSPQLKD</Hsp_hseq>
      <Hsp_midline>ILGEG+  +V   +     K +A+K +   +   E +   + RE +        + V+ +  F DE+   +Y  + Y   G+ L+      +++     E      +  ++  L +LH   +IHRD+KP+NILLNE   I++ DFG    +S  + ++ A +F GT+ Y++PE +  +    + D+W+LG  + ++  G  PF +     I Q +  +E       F P+ KD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.4925</Hsp_bit-score>
      <Hsp_score>197</Hsp_score>
      <Hsp_evalue>1.6815e-16</Hsp_evalue>
      <Hsp_query-from>484</Hsp_query-from>
      <Hsp_query-to>1089</Hsp_query-to>
      <Hsp_hit-from>11</Hsp_hit-from>
      <Hsp_hit-to>210</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>205</Hsp_align-len>
      <Hsp_qseq>KILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRS--FDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELL-TEKSACKSSDLWALGCIIYQLVAGLPPFRAPNE</Hsp_qseq>
      <Hsp_hseq>KKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAI-REVKYLQEMQHPNVIELIDIFMAYDNLNLVLEFLPTD--LEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIP--APHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQND</Hsp_hseq>
      <Hsp_midline>K +GEG+++ V L  + +TG++ AIK ++         +  + RE + L  + HP  ++L   F   + L   L +      L+ + K +S  F     + +    +  + H H   I+HRDLKP N+L + D  I++ DFG A+ +   + H    S V T  Y +PELL   K    + D+W++G I  +L+  +P     N+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YAR018C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:170396:171703:-1 gene:YAR018C transcript:YAR018C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN3 description:Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol [Source:SGD;Acc:S000000071]</Hit_def>
  <Hit_accession>YAR018C</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.6481</Hsp_bit-score>
      <Hsp_score>200</Hsp_score>
      <Hsp_evalue>2.19427e-16</Hsp_evalue>
      <Hsp_query-from>490</Hsp_query-from>
      <Hsp_query-to>1116</Hsp_query-to>
      <Hsp_hit-from>31</Hsp_hit-from>
      <Hsp_hit-to>301</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>70</Hsp_gaps>
      <Hsp_align-len>275</Hsp_align-len>
      <Hsp_qseq>LGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEK--LYFGLSYAKNG---EMLK-YIRKHRSFDENCTRFYSAQIVSSLEHLH------SLG---------------IIHRDLKPENILLNED---------------------------------------MHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIK</Hsp_qseq>
      <Hsp_hseq>IGRGSFGSVRKVIHIPTKKLLVRKDIKYGHMNSKERQQLIA-ECSILSQLKHENIVEFYNWDFDEQKEVLYLYMEYCSRGDLSQMIKHYKQEHKYIPEKIVWGILAQLLTALYKCHYGVELPTLTTIYDRMKPPVKGKNIVIHRDLKPGNIFLSYDDSDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLAKSLETSIQFA--TTYVGTPYYMSPEVLMDQPYSPLSDIWSLGCVIFEMCSLHPPFQAKN-YLELQTKIK</Hsp_hseq>
      <Hsp_midline>+G GSF +V     + T K    K ++  H+  +++   +  E  +LS+L H   V+ +    DE+K  LY  + Y   G   +M+K Y ++H+   E       AQ++++L   H      +L                +IHRDLKP NI L+ D                                       + +++ DFG AK L  + + A   ++VGT  Y+SPE+L ++     SD+W+LGC+I+++ +  PPF+A N YL  Q  IK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.4925</Hsp_bit-score>
      <Hsp_score>197</Hsp_score>
      <Hsp_evalue>4.81866e-16</Hsp_evalue>
      <Hsp_query-from>481</Hsp_query-from>
      <Hsp_query-to>1278</Hsp_query-to>
      <Hsp_hit-from>27</Hsp_hit-from>
      <Hsp_hit-to>324</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>82</Hsp_identity>
      <Hsp_positive>140</Hsp_positive>
      <Hsp_gaps>60</Hsp_gaps>
      <Hsp_align-len>312</Hsp_align-len>
      <Hsp_qseq>GKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEK-KVPYVNREKEVLSRL-NHPFFVKLFFTFQDEEKLYFGLSYAKNGEML----------KYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSK--HARANSFVGTAQYVSPELLTEKSAC-KSSDLWALGCIIYQLVAGLPPFRA-----------------PNEYL---IFQKIIKLEYEF---PEKFF--------PKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEISWDDL</Hsp_qseq>
      <Hsp_hseq>GKI-GRGSHSLICSSTYTESNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDT-----DIVFYPNGALNGVYLYEELMECDLSQIIRSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIPGRSFESILPGANPEALELLKKMLEFDPKKRITVEDA------LEHPYLS--MWHDI</Hsp_hseq>
      <Hsp_midline>GKI G GS S +  +    + +E  + I +  +    K       RE ++L  L  HP  V LF T      + F  + A NG  L          + IR  +  ++   + +  QI+ +L+++HS  ++H DLKP+N+L+N D  ++I +FG +   S+N K        ++ +  Y +PE+L     C K+ D+W+ GCI+ +L+   P F                   P E L     QK+    ++F   P + F        P+A +L++K+L  DP +R+  ++         HP+ S   W D+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.6481</Hsp_bit-score>
      <Hsp_score>200</Hsp_score>
      <Hsp_evalue>5.05787e-16</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>1074</Hsp_query-to>
      <Hsp_hit-from>360</Hsp_hit-from>
      <Hsp_hit-to>582</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>118</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>227</Hsp_align-len>
      <Hsp_qseq>FKFGKILGEGSFSTVVLAKEVATGKE--------YAIKILEKRHIIKEKKVPYVNREKEVLSRL---------NHPFFVKLFFTFQDEEKLYFGLSYAKNG---EMLKYIRKHRS------FDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPF</Hsp_qseq>
      <Hsp_hseq>FQLVEKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQPKKQLIMNELLVMNDSRQENIVNFLEAYII--DDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTE--KRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPPY</Hsp_hseq>
      <Hsp_midline>F+  +  G+G+   V L+K +   +E        +  +++ +R  IK+ ++    +++ +++ L         N   F++ +    D+E+L+  + Y + G   ++L  + +  +       +EN   +   +    L+ LH+  IIHRD+K +NILLN    ++ITDFG    L++  K ++  + VGT  +++PE++ +K   +  D+W+LG ++ +++ G PP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YDL025C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:405344:407206:-1 gene:YDL025C transcript:YDL025C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RTK1 description:Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002183]</Hit_def>
  <Hit_accession>YDL025C</Hit_accession>
  <Hit_len>620</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.8777</Hsp_bit-score>
      <Hsp_score>198</Hsp_score>
      <Hsp_evalue>8.80092e-16</Hsp_evalue>
      <Hsp_query-from>481</Hsp_query-from>
      <Hsp_query-to>1203</Hsp_query-to>
      <Hsp_hit-from>305</Hsp_hit-from>
      <Hsp_hit-to>564</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>129</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>264</Hsp_align-len>
      <Hsp_qseq>GKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKE--KKVPYVNREKEVL------SRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDE-NCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILS--DNSKHARANSFVGTAQYVSPELLTEKS-ACKSSDLWALGCIIYQLVAGLPPFRAP----NEYLIFQKIIKLEYEF---PEK---FFPK-AKDLVEKLLVSDPMQRL</Hsp_qseq>
      <Hsp_hseq>GRKLGEGASGSVSVV-ERTDGKLFACKMFRKPHLNNEGTNQSQLANYSKKVTTEFCIGSTLHHENIVETLDMLTEGDTYLLVMEYAPYDFFNLVMSNLMTQDEVNC---YFKQLCHGVNYLHSMGLAHRDLKLDNCVVTKDGILKLIDFGSAVVFQYPYEDTIVKSHGIVGSDPYLAPELLKQTSYDPRVADVWSIAIIFYCMVLKRFPWKAPKKSFNSFRLFTEEPEDEDDIVRGPNKILRLLPRHSRTIIGRMLALEPKQRV</Hsp_hseq>
      <Hsp_midline>G+ LGEG+  +V +  E   GK +A K+  K H+  E   +    N  K+V       S L+H   V+      + +     + YA        +    + DE NC   Y  Q+   + +LHS+G+ HRDLK +N ++ +D  +++ DFG+A +          +++  VG+  Y++PELL + S   + +D+W++  I Y +V    P++AP    N + +F +  + E +    P K     P+ ++ ++ ++L  +P QR+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YDL028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:400997:403291:-1 gene:YDL028C transcript:YDL028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MPS1 description:Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]</Hit_def>
  <Hit_accession>YDL028C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.8777</Hsp_bit-score>
      <Hsp_score>198</Hsp_score>
      <Hsp_evalue>1.03943e-15</Hsp_evalue>
      <Hsp_query-from>730</Hsp_query-from>
      <Hsp_query-to>1335</Hsp_query-to>
      <Hsp_hit-from>523</Hsp_hit-from>
      <Hsp_hit-to>747</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>230</Hsp_align-len>
      <Hsp_qseq>LKYIRKHRS---FDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKS---------------SDLWALGCIIYQLVAGLPP---FRAPNEYL-IFQKIIKLEYEFP------EKFFPKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEISWDDLHLQTPPKLTAYLPAMTEDD</Hsp_qseq>
      <Hsp_hseq>LSQILNQRSGMPLDFNFVRFYTKEMLLCIKVVHDAGIVHSDLKPANFVLVKGI-LKIIDFGIANAVPEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYGKPPYGSFQGQNRLLAIMNPDVKI--PFPEHTSNNEKIPKSAIELMKACLYRNPDKRWTVDKVLSSTFLQ--PFMISGSIMEDLIRNAVRYGSEKPHISQDD</Hsp_hseq>
      <Hsp_midline>L  I   RS    D N  RFY+ +++  ++ +H  GI+H DLKP N +L + + ++I DFG A  + +++ +    + +GT  Y++PE L   +  ++               SD+W+ GCIIYQ++ G PP   F+  N  L I    +K+   FP      EK    A +L++  L  +P +R   D+      L+  PF    S  +  ++   +  +  P +++DD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.7221</Hsp_bit-score>
      <Hsp_score>195</Hsp_score>
      <Hsp_evalue>2.10759e-15</Hsp_evalue>
      <Hsp_query-from>466</Hsp_query-from>
      <Hsp_query-to>1284</Hsp_query-to>
      <Hsp_hit-from>358</Hsp_hit-from>
      <Hsp_hit-to>633</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>124</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>288</Hsp_align-len>
      <Hsp_qseq>EDFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHR---SFDENCTRFYSAQIVSSLEHLHSL-GIIHRDLKPENILLNEDM-HIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKS-----SDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFP-----EKFFPKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEISWDDLHL</Hsp_qseq>
      <Hsp_hseq>DELEFLDELGHGNYGNVSKVLHKPTNVIMATK--EVRLELDEAKFRQILMELEVLHKCNSPYIVDFYGAFFIEGAVYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSANQGTVKLCDFG----VSGNLVASLAKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYPPETYDNIFSQLSAIVDGPPPRLPSDKFSSDAQDFVSLCLQKIPERR------PTYAALTEHPWLVKYRNQDVHM</Hsp_hseq>
      <Hsp_midline>++ +F   LG G++  V       T    A K  E R  + E K   +  E EVL + N P+ V  +  F  E  +Y  + Y   G + K   +       DE    F +  ++  L+ L     IIHRD+KP NIL + +   +++ DFG    +S N   + A + +G   Y++PE +   +  ++     SD+W+LG  I ++  G  P+       IF ++  +    P     +KF   A+D V   L   P +R        Y  L  HP+  +    D+H+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>71</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.1073</Hsp_bit-score>
      <Hsp_score>196</Hsp_score>
      <Hsp_evalue>2.11385e-15</Hsp_evalue>
      <Hsp_query-from>652</Hsp_query-from>
      <Hsp_query-to>1239</Hsp_query-to>
      <Hsp_hit-from>771</Hsp_hit-from>
      <Hsp_hit-to>984</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>219</Hsp_align-len>
      <Hsp_qseq>FVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRK---HRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAK-------ILSDNSKHA-----RANSFVGTAQYVSPELLTEKSACKSS-DLWALGCIIYQLVAGLPPFRAPNEYL-IFQKIIKLEYEFPEKF----FPKAKDLVEKLLVSDPMQRLGCDEC--GGYPPLK</Hsp_qseq>
      <Hsp_hseq>FVKPMTAVKKKSTLFIQMEYCENRTLYDLIHSENLNQQRDEYWRLF--RQILEALSYIHSQGIIHRDLKPMNIFIDESRNVKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVLDGTGHYNEKIDMYSLGIIFFEMIY---PFSTGMERVNILKKLRSVSIEFPPDFDDNKMKVEKKIIRLLIDHDPNKRPGARTLLNSGWLPVK</Hsp_hseq>
      <Hsp_midline>FVK     + +  L+  + Y +N  +   I     ++  DE    F   QI+ +L ++HS GIIHRDLKP NI ++E  +++I DFG AK       IL  +S++         S +GTA YV+ E+L          D+++LG I ++++    PF    E + I +K+  +  EFP  F        K ++  L+  DP +R G       G+ P+K</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>2.1984e-08</Hsp_evalue>
      <Hsp_query-from>769</Hsp_query-from>
      <Hsp_query-to>1218</Hsp_query-to>
      <Hsp_hit-from>369</Hsp_hit-from>
      <Hsp_hit-to>521</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>169</Hsp_align-len>
      <Hsp_qseq>CTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTA-----------KILSDNSKHARANSF---VGTAQYVSPELLTEKSA--CKSSDLWALGCIIYQLVAG---LPPFRAPNEYLIFQKIIKLEYEFPEKFFPKAKDLVEKLLVSDPMQRLGCDEC</Hsp_qseq>
      <Hsp_hseq>TARIWMIRLLEGLEAIHKLGIVHKCINLETVILVKD-----ADFGSTIPKLVHSTYGYTVLNMLSRYPNKNGSSVELSPSTWIAPELLKFNNAKPQRLTDIWQLGVLFIQIISGSDIVMNFETPQEFLDSTSMDETLY-----------DLLSKMLNNDPKKRLGTLEL</Hsp_hseq>
      <Hsp_midline>  R +  +++  LE +H LGI+H+ +  E ++L +D      DFG+             +L+  S++   N     +  + +++PELL   +A   + +D+W LG +  Q+++G   +  F  P E+L    + +  Y           DL+ K+L +DP +RLG  E </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>72</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.5666</Hsp_bit-score>
      <Hsp_score>192</Hsp_score>
      <Hsp_evalue>3.31313e-15</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>1089</Hsp_query-to>
      <Hsp_hit-from>192</Hsp_hit-from>
      <Hsp_hit-to>409</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>223</Hsp_align-len>
      <Hsp_qseq>FKFGKILGEGSFSTVVLAKEVATGKEYAIKIL---EKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSF-------------DENCTRFYSAQIVSSLEHLH-SLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNE</Hsp_qseq>
      <Hsp_hseq>VQLGKI-GAGNSGTVVKALHVPDSKIVAKKTIPVEQNNSTIINQLVRELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKLIN----SIADTFVGTSTYMSPERIQGNVYSIKGDVWSLGLMIIELVTGEFPLGGHND</Hsp_hseq>
      <Hsp_midline> + GKI G G+  TVV A  V   K  A K +   +    I  + V  ++  K V    N   F   ++      ++   + Y+  G + K +  ++ F             +E      +  +++ L+HL+    IIHRD+KP N+L+N    I++ DFG +K L +    + A++FVGT+ Y+SPE +         D+W+LG +I +LV G  P    N+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>73</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.7962</Hsp_bit-score>
      <Hsp_score>190</Hsp_score>
      <Hsp_evalue>5.62158e-15</Hsp_evalue>
      <Hsp_query-from>490</Hsp_query-from>
      <Hsp_query-to>1119</Hsp_query-to>
      <Hsp_hit-from>189</Hsp_hit-from>
      <Hsp_hit-to>396</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>213</Hsp_align-len>
      <Hsp_qseq>LGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVN-REKEVLSRLNHPFFVKLF-FTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSS-DLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKL</Hsp_qseq>
      <Hsp_hseq>VGEGTYGKVYKAKNTNTEKLVALKKL--RLQGEREGFPITSIREIKLLQSFDHPNVSTIKEIMVESQKTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKM--NSRADYTNRVI-TLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKI</Hsp_hseq>
      <Hsp_midline>+GEG++  V  AK   T K  A+K L  R   + +  P  + RE ++L   +HP    +     + ++ +Y    YA N      + K      +  +    Q++  +E+LH   I+HRD+K  NIL++   +++ITDFG A+ +  NS+    N  + T  Y  PELL   +   +  D+W  GC++ +L      F+  NE    + I K+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>74</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.6406</Hsp_bit-score>
      <Hsp_score>187</Hsp_score>
      <Hsp_evalue>1.66893e-14</Hsp_evalue>
      <Hsp_query-from>475</Hsp_query-from>
      <Hsp_query-to>1062</Hsp_query-to>
      <Hsp_hit-from>314</Hsp_hit-from>
      <Hsp_hit-to>525</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>213</Hsp_align-len>
      <Hsp_qseq>KFGK---ILGEGSFSTVVLA--KEVATG------KEYAIKILEKRHI-IKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFG-LSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTA---KILSDNSKHARANSFVGTAQYVSP-ELLTEKSACKSSDLWALGCIIYQLVAG</Hsp_qseq>
      <Hsp_hseq>KYGRCQEVLGKGAFGVVRICQKKNVSSQDGNKSEKLYAVKEFKRRTSESAEKYSKRLTSEFCISSSLHHTNIVTTLDLFQDAKGEYCEVMEYCAGGDLFTLVVAAGKLEYMEADCFFKQLIRGVVYMHEMGVCHRDLKPENLLLTHDGVLKITDFGNSECFKMAWEKNIHL-SGGVCGSSPYIAPEEYIKEEFDPRPVDIWACGVIYMAMRTG</Hsp_hseq>
      <Hsp_midline>K+G+   +LG+G+F  V +   K V++       K YA+K  ++R     EK    +  E  + S L+H   V     FQD +  Y   + Y   G++   +      +      +  Q++  + ++H +G+ HRDLKPEN+LL  D  ++ITDFG +   K+  + + H  +    G++ Y++P E + E+   +  D+WA G I   +  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>75</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.485</Hsp_bit-score>
      <Hsp_score>184</Hsp_score>
      <Hsp_evalue>1.79755e-14</Hsp_evalue>
      <Hsp_query-from>451</Hsp_query-from>
      <Hsp_query-to>1263</Hsp_query-to>
      <Hsp_hit-from>31</Hsp_hit-from>
      <Hsp_hit-to>340</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>83</Hsp_identity>
      <Hsp_positive>140</Hsp_positive>
      <Hsp_gaps>67</Hsp_gaps>
      <Hsp_align-len>324</Hsp_align-len>
      <Hsp_qseq>RKKRPEDFKFGKILGEGSFSTVVLAK--------EVATGKEYAI---KILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAK--NGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKIL------SDNSKHARANSFVGTAQYVSPE-LLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKL----EYEFPEKF-------------------------FP----KAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEI</Hsp_qseq>
      <Hsp_hseq>RISIPGYYEIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGHKNIVNLIDLEIV-----TSSPYDGLY---CYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDKDILIKFGTIKAWNLGKNSNNPVYKKIPWSNIFPFASHEAINLIESLLHWDSTHRLNVEQA------ISHPFLNEV</Hsp_hseq>
      <Hsp_midline>R   P  ++  + LG+G++ TV   K         +A  K   I   +IL KR I + K + +    K +++ ++         T    + LY    Y +  + ++ K I       E   +++  QI+  L+++HS  +IHRDLKP NIL   +  ++I DFG A+ +        ++      ++V T  Y +PE LL+ +   KS D+WA+GCI+ +  A  P F   +      +IIK+    + +   KF                         FP    +A +L+E LL  D   RL  ++        SHPF +E+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>76</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.6406</Hsp_bit-score>
      <Hsp_score>187</Hsp_score>
      <Hsp_evalue>1.93166e-14</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>1074</Hsp_query-to>
      <Hsp_hit-from>546</Hsp_hit-from>
      <Hsp_hit-to>768</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>233</Hsp_align-len>
      <Hsp_qseq>FKFGKILGEGSFSTVVLAK-------------------EVATGKEYAIKIL------EKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIV-------SSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPF</Hsp_qseq>
      <Hsp_hseq>FKVIEKAGQGASGSVYLAERTHIPTESNMIELINNDIDEPHVGDKVAIKQMVLSKQPRKELIVNEILVMKDSRHKNIVN------FLEAYLRTDDD--LWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTD--KRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPY</Hsp_hseq>
      <Hsp_midline>FK  +  G+G+  +V LA+                   E   G + AIK +       K  I+ E  V   +R K +++      F++ +    D+  L+  + + + G +   I    + D + +     QI          L+ LH   IIHRD+K +N+LL+    ++ITDFG    L+D  K ++  + VGT  +++PE++ ++   +  D+W+LG +  +++ G PP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>77</Hit_num>
  <Hit_id>YNL183C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:293137:295509:-1 gene:YNL183C transcript:YNL183C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NPR1 description:Protein kinase; stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p; negatively regulates Ldb19p-mediated endocytosis through phosphorylation of Ldb19p, which prevents its association with the plasma membrane; Npr1p activity is negatively regulated via phosphorylation by the TOR complex; NPR1 has a paralog, PRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005127]</Hit_def>
  <Hit_accession>YNL183C</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.485</Hsp_bit-score>
      <Hsp_score>184</Hsp_score>
      <Hsp_evalue>4.52941e-14</Hsp_evalue>
      <Hsp_query-from>511</Hsp_query-from>
      <Hsp_query-to>1101</Hsp_query-to>
      <Hsp_hit-from>451</Hsp_hit-from>
      <Hsp_hit-to>654</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>206</Hsp_align-len>
      <Hsp_qseq>TVVLAKEVATGKEYAIKILEKRHIIKEKK--VPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSD--NSKHARANSFVGTAQYVSPEL-LTEKSACKSSDLWALGCIIYQLVAGLPPFRAP----NEYLIF</Hsp_qseq>
      <Hsp_hseq>SVKLAQRISDNKIFAVKEFRTKFENESKRDYVKKITSEYCIGTTLNHPNIIETIEIVYENDRILQVMEYCEYDLFAIVMSNKMSYEEICCCF--KQILTGVQYLHSIGLAHRDLKLDNCVINEKGIVKLIDFGAAVVFSYPFSKNLVEASGIVGSDPYLAPEVCIFAKYDPRPVDIWSSAIIFACMILKKFPWKIPKLRDNSFKLF</Hsp_hseq>
      <Hsp_midline>+V LA+ ++  K +A+K    +   + K+  V  +  E  + + LNHP  ++      + +++   + Y +       +    S++E C  F   QI++ +++LHS+G+ HRDLK +N ++NE   +++ DFG A + S   +     A+  VG+  Y++PE+ +  K   +  D+W+   I   ++    P++ P    N + +F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>78</Hit_num>
  <Hit_id>YDL214C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:74446:76545:-1 gene:YDL214C transcript:YDL214C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR2 description:Serine/threonine protein kinase; inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance; PRR2 has a paralog, NPR1, that arose from the whole genome duplication [Source:SGD;Acc:S000002373]</Hit_def>
  <Hit_accession>YDL214C</Hit_accession>
  <Hit_len>699</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.3294</Hsp_bit-score>
      <Hsp_score>181</Hsp_score>
      <Hsp_evalue>1.05786e-13</Hsp_evalue>
      <Hsp_query-from>451</Hsp_query-from>
      <Hsp_query-to>1083</Hsp_query-to>
      <Hsp_hit-from>358</Hsp_hit-from>
      <Hsp_hit-to>567</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>216</Hsp_align-len>
      <Hsp_qseq>RKKRPEDFKFGKILGEGSFSTVVLAKEVATGKEYAIKIL--EKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSD--NSKHARANSFVGTAQYVSPELLT-EKSACKSSDLWALGCIIYQLVAGLPPFRAP</Hsp_qseq>
      <Hsp_hseq>RKYRDLDV----VLGEGSGGKVKLVQRVLDNKVFALKEYRSKKKRESERKYIKNIISEYCIASTLKNPNICETLEILYEKGKIFQILEYCEYDLFSLVMSEKMHYEEICCLF--KQLINGVKYLHDIGLSHRDLKLDNCVVTRRGILKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFYFNEYDPRALDVWSVGIIFFCMITRRFPWKYP</Hsp_hseq>
      <Hsp_midline>RK R  D     +LGEGS   V L + V   K +A+K    +K+   + K +  +  E  + S L +P   +      ++ K++  L Y +       + +   ++E C  F   Q+++ +++LH +G+ HRDLK +N ++     +++ DFG + +     +S+   AN  VG+  Y+SPE+    +   ++ D+W++G I + ++    P++ P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>79</Hit_num>
  <Hit_id>YHR079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:258244:261591:-1 gene:YHR079C transcript:YHR079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IRE1 description:Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; role in homeostatic adaptation to ER stress; Kar2p binds inactive Ire1p and releases from it upon ER stress [Source:SGD;Acc:S000001121]</Hit_def>
  <Hit_accession>YHR079C</Hit_accession>
  <Hit_len>1115</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>3.01862e-13</Hsp_evalue>
      <Hsp_query-from>484</Hsp_query-from>
      <Hsp_query-to>1200</Hsp_query-to>
      <Hsp_hit-from>678</Hsp_hit-from>
      <Hsp_hit-to>968</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>130</Hsp_positive>
      <Hsp_gaps>68</Hsp_gaps>
      <Hsp_align-len>299</Hsp_align-len>
      <Hsp_qseq>KILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLN-HPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENC--TRFYS-----AQIVSSLEHLHSLGIIHRDLKPENILLN-------------EDMHIQITDFGTAKILSDNSKHARA--NSFVGTAQYVSPELL-------------------------------TEKSACKSSDLWALGCIIYQLVA-GLPPF--RAPNEYLIFQKIIKLEYE---FPEKFFPKAKDLVEKLLVSDPMQR</Hsp_qseq>
      <Hsp_hseq>KILGYGSSGTVVFQGSFQ-GRPVAVK----RMLIDFCDIALM--EIKLLTESDDHPNVIRYYCSETTDRFLYIALELC-NLNLQDLVESKNVSDENLKLQKEYNPISLLRQIASGVAHLHSLKIIHRDLKPQNILVSTSSRFTADQQTGAENLRILISDFGLCKKLDSGQSSFRTNLNNPSGTSGWRAPELLEESNNLQCQVETEHSSSRHTVVSSDSFYDPFTKRRLTRSIDIFSMGCVFYYILSKGKHPFGDKYSRESNIIRGIFSLDEMKCLHDRSLIAEATDLISQMIDHDPLKR</Hsp_hseq>
      <Hsp_midline>KILG GS  TVV       G+  A+K    R +I    +  +  E ++L+  + HP  ++ + +   +  LY  L    N  +   +      DEN    + Y+      QI S + HLHSL IIHRDLKP+NIL++             E++ I I+DFG  K L       R   N+  GT+ + +PELL                               T++   +S D++++GC+ Y +++ G  PF  +   E  I + I  L+            +A DL+ +++  DP++R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>80</Hit_num>
  <Hit_id>YOR061W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:441534:442553:1 gene:YOR061W transcript:YOR061W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA2 description:Alpha&apos; catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000005587]</Hit_def>
  <Hit_accession>YOR061W</Hit_accession>
  <Hit_len>339</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>4.00703e-13</Hsp_evalue>
      <Hsp_query-from>490</Hsp_query-from>
      <Hsp_query-to>1074</Hsp_query-to>
      <Hsp_hit-from>56</Hsp_hit-from>
      <Hsp_hit-to>243</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>200</Hsp_align-len>
      <Hsp_qseq>LGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNH-PFFVKLFFTFQDEEKLYFGLSY--AKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLN-EDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSS-DLWALGCIIYQLVAGLPPF</Hsp_qseq>
      <Hsp_hseq>IGRGKYSEVFSGRCIVNNQKCVIKVLKP---VKMKKI---YRELKILTNLTGGPNVVGLYDIVQDADSKIPALIFEEIKN---VDFRTLYPTFKLPDIQYYFTQLLIALDYCHSMGIMHRDVKPQNVMIDPTERKLRLIDWGLAEFYHPGVDY---NVRVASRYHKGPELLVNLNQYDYSLDLWSVGCMLAAIVFKKEPF</Hsp_hseq>
      <Hsp_midline>+G G +S V   + +   ++  IK+L+    +K KK+    RE ++L+ L   P  V L+   QD +     L +   KN   + +   + +F     ++Y  Q++ +L++ HS+GI+HRD+KP+N++++  +  +++ D+G A+       +   N  V +  +  PELL   +    S DLW++GC++  +V    PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>81</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>7.80992e-13</Hsp_evalue>
      <Hsp_query-from>787</Hsp_query-from>
      <Hsp_query-to>1089</Hsp_query-to>
      <Hsp_hit-from>189</Hsp_hit-from>
      <Hsp_hit-to>294</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>111</Hsp_align-len>
      <Hsp_qseq>AQIVSSLEHLHSLGIIHRDLKPENILLNE-DMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELL---------TEKSACKSSDLWALGCIIYQLVAGLPPFRAPNE</Hsp_qseq>
      <Hsp_hseq>TQIMDAIEYVHNKGIYHRDIKPENILISGIDWTIKLTDWGLA--TTDKTSMDRN---VGSERYMSPELFDSNLDIKERKEPYDCAKVDLWAMGIVFLNIVFHKNPFSIANQ</Hsp_hseq>
      <Hsp_midline> QI+ ++E++H+ GI HRD+KPENIL++  D  I++TD+G A   +D +   R    VG+ +Y+SPEL           E   C   DLWA+G +   +V    PF   N+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>82</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>2.57369e-12</Hsp_evalue>
      <Hsp_query-from>448</Hsp_query-from>
      <Hsp_query-to>1119</Hsp_query-to>
      <Hsp_hit-from>30</Hsp_hit-from>
      <Hsp_hit-to>300</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>119</Hsp_positive>
      <Hsp_gaps>59</Hsp_gaps>
      <Hsp_align-len>277</Hsp_align-len>
      <Hsp_qseq>PRKKRPEDFKFGKILGEGSFSTVVLAK-----EVATGKEYAIK--------------------------ILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEE--KLYFGLSYAKNG--EMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLN-----------------EDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKS-ACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKL</Hsp_qseq>
      <Hsp_hseq>PLKTLSDRYQLIEKLGAGSFGCVTLAKAQFPLSNILGKQHDIRGTLMDQPKNGHQNYITKTQGVVAIKTMMTKLHTLQD--YTRVREIKFILAIPANDHLIQIFEVFIDSENYQLHIVMECMEQNLYQMMKH-RRRRVFSIPSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVENKNPYT---AYVSTRWYRSPEILLRSGYYSKPLDIWAFGCVAVEVTVFRALFPGANEIDQIWKILEV</Hsp_hseq>
      <Hsp_midline>P K   + ++  + LG GSF  V LAK         GK++ I+                          ++ K H +++     V   K +L+   +   +++F  F D E  +L+  +   +    +M+K+ R+ R F     +   +QI++ L+H+H     HRDLKPENIL+                  ++  I++ DFG A+ + + + +    ++V T  Y SPE+L       K  D+WA GC+  ++      F   NE     KI+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>83</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.3218</Hsp_bit-score>
      <Hsp_score>168</Hsp_score>
      <Hsp_evalue>2.74328e-12</Hsp_evalue>
      <Hsp_query-from>460</Hsp_query-from>
      <Hsp_query-to>1083</Hsp_query-to>
      <Hsp_hit-from>188</Hsp_hit-from>
      <Hsp_hit-to>448</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>61</Hsp_gaps>
      <Hsp_align-len>265</Hsp_align-len>
      <Hsp_qseq>RPEDFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEK--KVPYVN-----------------REKEVLSRLNHPFFVKLFFT----FQDEEKLYFGL---------------SYAKNGEMLKYI--RKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLN---EDMH-------------IQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLT-EKSACKSSDLWALGCIIYQLVAGLPPFRAP</Hsp_qseq>
      <Hsp_hseq>RPLLWKKVRPIGSGNFSTVLLYELMDQSNPKLKQVAVKRLKYPEELSNVEQINTSLRYKETLSRLENSLTRELQVLKSLNHPCIVKLLGINNPIFVTSKKPLCDLIIKTPRALPPCDMIMSYCPAGDLLAAVMARNGRLEAWLIQRIFT-EVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLCKKIENNEM---CTARCGSEDYVSPEILMGVPYDGHLSDTWALGVILYSLFEDRLPFDPP</Hsp_hseq>
      <Hsp_midline>RP  +K  + +G G+FSTV+L + +        ++  KR    E+   V  +N                 RE +VL  LNHP  VKL       F   +K    L               SY   G++L  +  R  R       R ++ ++V ++++LH   IIHRDLK ENILL    +D++             I++ DFG  K + +N       +  G+  YVSPE+L         SD WALG I+Y L     PF  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>84</Hit_num>
  <Hit_id>YOR267C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:822588:824867:-1 gene:YOR267C transcript:YOR267C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRK1 description:Protein kinase; implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005793]</Hit_def>
  <Hit_accession>YOR267C</Hit_accession>
  <Hit_len>759</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.5514</Hsp_bit-score>
      <Hsp_score>166</Hsp_score>
      <Hsp_evalue>5.80274e-12</Hsp_evalue>
      <Hsp_query-from>475</Hsp_query-from>
      <Hsp_query-to>1089</Hsp_query-to>
      <Hsp_hit-from>216</Hsp_hit-from>
      <Hsp_hit-to>426</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>214</Hsp_align-len>
      <Hsp_qseq>KFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKK--VPYVNREKEVLSRLNHPFFVKLFFTFQD--EEKLYFGLSYAKNGEMLKYIRKHRSFDE-NCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSD--NSKHARANSFVGTAQYVSPELLTEKSAC--KSSDLWALGCIIYQLVAGLPPFRAPNE</Hsp_qseq>
      <Hsp_hseq>KLGKLLGSGAGGSVKVLVRPTDGATFAVKEFRPRKPNESVKEYAKKCTAEFCIGSTLHHPNVIETVDVFSDSKQNKYYEVMEYCPIDFFAVVMTGKMSRGEINCCL---KQLTEGVKYLHSMGLAHRDLKLDNCVMTSQGILKLIDFGSAVVFRYPFEDGVTMAHGIVGSDPYLAPEVITSTKSYDPQCVDIWSIGIIYCCMVLKRFPWKAPRD</Hsp_hseq>
      <Hsp_midline>K GK+LG G+  +V +      G  +A+K    R   +  K        E  + S L+HP  ++    F D  + K Y  + Y         +    S  E NC      Q+   +++LHS+G+ HRDLK +N ++     +++ DFG+A +           A+  VG+  Y++PE++T   +   +  D+W++G I   +V    P++AP +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>85</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>6.99463e-12</Hsp_evalue>
      <Hsp_query-from>490</Hsp_query-from>
      <Hsp_query-to>1080</Hsp_query-to>
      <Hsp_hit-from>8</Hsp_hit-from>
      <Hsp_hit-to>224</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>LGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLN-HPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRS--------FDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSF-VGTAQYVSPELLTEK--SAC---------------KSSDLWALGCIIYQLVAGLPPFRA</Hsp_qseq>
      <Hsp_hseq>IQSGTFSTVYKAWSTTHNRYVALKITPK-YKTSEANMKNEYDVMKILSSCNPHPNICSMLDFYTDDSYYIMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQIDMQKIIKQLCSAISFAHSLGIAHRDIKPENILLTINGDIKLADWGHA------IQSPKSNDFQIGTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFGDCLFRV</Hsp_hseq>
      <Hsp_midline>+  G+FSTV  A      +  A+KI  K +   E  +       ++LS  N HP    +   + D+      L Y + G++  ++   +S          +   +    Q+ S++   HSLGI HRD+KPENILL  +  I++ D+G A       +  ++N F +GT  Y +PE  + +  ++C                 +D W+LG  I+ L+ G   FR </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>86</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>1.07909e-11</Hsp_evalue>
      <Hsp_query-from>490</Hsp_query-from>
      <Hsp_query-to>1260</Hsp_query-to>
      <Hsp_hit-from>66</Hsp_hit-from>
      <Hsp_hit-to>374</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>124</Hsp_positive>
      <Hsp_gaps>62</Hsp_gaps>
      <Hsp_align-len>314</Hsp_align-len>
      <Hsp_qseq>LGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPY---VNREKEVLSRLNHPFFVKLFFTFQDE-------------EKLYFGLSYAKNGEMLKYIRKHRSFDENC-TRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKIL---SDNSKH-------ARANSFVGTAQYVSPEL-LTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKL------EYEFPEKFFPKAK-----------------------DLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSE</Hsp_qseq>
      <Hsp_hseq>LGQGTFGEVYKGIHLETQRQVAMKKI----IVSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMV-ADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTEEDWAVARYLPGAELTTTNYKPTLRERFGKYLSETGLDFLGQLLALDPYKRLTAMSAKHHPWFKEDPLPSE</Hsp_hseq>
      <Hsp_midline>LG+G+F  V     + T ++ A+K +    I+  +K  +     RE  +L RLNH   +KL     D              +  Y  L Y    ++   +   R   E C  +    QI+  L ++H    +HRD+K  NIL++ +  +++ DFG A++      N K+       A+  S V T  Y +PEL L +K    + D+W +GC+  +     P  +   +      I KL      E     ++ P A+                       D + +LL  DP +RL       +P  K  P  SE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>87</Hit_num>
  <Hit_id>YIL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:287790:288908:-1 gene:YIL035C transcript:YIL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA1 description:Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000001297]</Hit_def>
  <Hit_accession>YIL035C</Hit_accession>
  <Hit_len>372</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>1.14208e-11</Hsp_evalue>
      <Hsp_query-from>775</Hsp_query-from>
      <Hsp_query-to>1263</Hsp_query-to>
      <Hsp_hit-from>173</Hsp_hit-from>
      <Hsp_hit-to>366</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>203</Hsp_align-len>
      <Hsp_qseq>RFYSAQIVSSLEHLHSLGIIHRDLKPENILLN-EDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSS-DLWALGCIIYQLVAGLPPF---RAPNEYLI----------FQK-IIKLEYEFPEKFFPKAK------------------------DLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEI</Hsp_qseq>
      <Hsp_hseq>RFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEY---NVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLLKYEITLPREFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMG------HPWFAPI</Hsp_hseq>
      <Hsp_midline>RFY  +++ +L++ HS+GI+HRD+KP N++++ ++  +++ D+G A+    N ++   N  V +  +  PELL +      S DLW+ G ++  ++    PF    +  + L+          F+K ++K E   P +F+   +                        DL++ LL  D  +RL   E  G      HP+F+ I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>88</Hit_num>
  <Hit_id>YPL204W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:164276:165760:1 gene:YPL204W transcript:YPL204W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRR25 description:Conserved casein kinase; regulates diverse events including: vesicular traffic, DNA repair, the CVT pathway, monopolar attachment of sister kinetochores at meiosis I, and ribosomal subunit biogenesis; monopolin subunit; binds the RNAPII CTD; phosphorylates COPII coat subunits; interacts with Sit4p phosphatase; antagonizes calcineurin signaling, reducing nuclear accumulation of Crz1p; phosphorylates Dsn1p, the kinetochore receptor for monopolin; homolog of mammalian CK1delta [Source:SGD;Acc:S000006125]</Hit_def>
  <Hit_accession>YPL204W</Hit_accession>
  <Hit_len>494</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>1.33715e-11</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>1080</Hsp_query-to>
      <Hsp_hit-from>9</Hsp_hit-from>
      <Hsp_hit-to>215</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>211</Hsp_align-len>
      <Hsp_qseq>FKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILL---NEDMHIQITDFGTAKILSDNSKHA----RAN-SFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRA</Hsp_qseq>
      <Hsp_hseq>FRIGRKIGSGSFGDIYHGTNLISGEEVAIKLESIRS--RHPQLDYESRVYRYLSGGVGIPFIRWFGREGEYNAMVIDLLGPSLEDLFNYC--HRRFSFKTVIMLALQMFCRIQYIHGRSFIHRDIKPDNFLMGVGRRGSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLTGTARYASVNTHLGIEQSRRDDLESLGYVLIYFCKGSLPWQG</Hsp_hseq>
      <Hsp_midline>F+ G+ +G GSF  +     + +G+E AIK+   R   +  ++ Y +R    LS      F++ F    +   +   L      ++  Y   HR F        + Q+   ++++H    IHRD+KP+N L+        + + DFG +K   D + H     R N S  GTA+Y S          +  DL +LG ++     G  P++ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>89</Hit_num>
  <Hit_id>YKL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:347214:349136:-1 gene:YKL048C transcript:YKL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ELM1 description:Serine/threonine protein kinase; regulates the orientation checkpoint, the morphogenesis checkpoint and the metabolic switch from fermentative to oxidative metabolism by phosphorylating the activation loop of Kin4p, Hsl1p and Snf4p respectively; cooperates with Hsl7p in recruiting Hsl1p to the septin ring, a prerequisite for subsequent recruitment, phosphorylation, and degradation of Swe1p; forms part of the bud neck ring; regulates cytokinesis [Source:SGD;Acc:S000001531]</Hit_def>
  <Hit_accession>YKL048C</Hit_accession>
  <Hit_len>640</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>1.95799e-11</Hsp_evalue>
      <Hsp_query-from>805</Hsp_query-from>
      <Hsp_query-to>1119</Hsp_query-to>
      <Hsp_hit-from>247</Hsp_hit-from>
      <Hsp_hit-to>369</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>123</Hsp_align-len>
      <Hsp_qseq>LEHLHSLGIIHRDLKPENILLNEDMHI-QITDFGTAKILSDNSKHARA----------NSFVGTAQYVSPELLTEKSACKS-------SDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKL</Hsp_qseq>
      <Hsp_hseq>LEYLHSQGCIHRDIKPSNILLDEEEKVAKLSDFGSCIFTPQSLPFSDANFEDCFQRELNKIVGTPAFIAPELCHLGNSKRDFVTDGFKLDIWSLGVTLYCLLYNELPFFGENEFETYHKIIEV</Hsp_hseq>
      <Hsp_midline>LE+LHS G IHRD+KP NILL+E+  + +++DFG+      +   + A          N  VGT  +++PEL    ++ +         D+W+LG  +Y L+    PF   NE+  + KII++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>90</Hit_num>
  <Hit_id>YHR135C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:372694:374310:-1 gene:YHR135C transcript:YHR135C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YCK1 description:Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform; shares redundant functions with Yck2p in morphogenesis, proper septin assembly, endocytic trafficking, and glucose sensing; stabilized by Sod1p binding in the presence of glucose and oxygen, causing glucose repression of respiratory metabolism; involved in the phosphorylation and regulation of glucose sensor Rgt2p; YCK1 has a paralog, YCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001177]</Hit_def>
  <Hit_accession>YHR135C</Hit_accession>
  <Hit_len>538</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>3.42946e-11</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>1110</Hsp_query-to>
      <Hsp_hit-from>69</Hsp_hit-from>
      <Hsp_hit-to>290</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>228</Hsp_align-len>
      <Hsp_qseq>FKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKH--RSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLN-----EDMHIQITDFGTAKILSD-----NSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPF---RAPNEYLIFQKI</Hsp_qseq>
      <Hsp_hseq>YKIGKKIGEGSFGVLFEGTNMINGVPVAIKFEPRK-----TEAPQLRDEYKTYKILNGTPNIPYAYYF-GQEGLHNILVIDLLGPSLEDLFDWCGRKFSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANNIHLIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGHLPWQGLKAPNNKQKYEKI</Hsp_hseq>
      <Hsp_midline>+K GK +GEGSF  +     +  G   AIK   ++      + P +  E +    LN    +   + F  +E L+  L     G  L+ +     R F        + Q+++ +E LH+  +I+RD+KP+N L+      +  +I + DFG AK   D     +  +    S  GTA+Y+S      +   +  D+ ALG + +  + G  P+   +APN    ++KI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>91</Hit_num>
  <Hit_id>YIL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:183937:186369:1 gene:YIL095W transcript:YIL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRK1 description:Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton and reduces endocytic ability of cell through the phosphorylation of the Pan1p-Sla1p-End3p protein complex; PRK1 has a paralog, ARK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001357]</Hit_def>
  <Hit_accession>YIL095W</Hit_accession>
  <Hit_len>810</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>3.84035e-11</Hsp_evalue>
      <Hsp_query-from>787</Hsp_query-from>
      <Hsp_query-to>1200</Hsp_query-to>
      <Hsp_hit-from>138</Hsp_hit-from>
      <Hsp_hit-to>285</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>152</Hsp_align-len>
      <Hsp_qseq>AQIVSSLEHLHSLG--IIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFV-------GTAQYVSPELLTEKSAC---KSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPE--KFFPKAKDLVEKLLVSDPMQR</Hsp_qseq>
      <Hsp_hseq>SQTVQGITAMHALQPPLIHRDIKIENVLISHDGLYKVCDFGSVSGVIRPPRNTQEFNYVQHDILTNTTAQYRSPEMIDLYRGLPIDEKSDIWALGVFLYKICYYTTPFEKSGE----AGILHARYQYPSFPQYSDRLKNLIRLMLMEAPSQR</Hsp_hseq>
      <Hsp_midline>+Q V  +  +H+L   +IHRD+K EN+L++ D   ++ DFG+   +    ++ +  ++V        TAQY SPE++         + SD+WALG  +Y++     PF    E      I+   Y++P   ++  + K+L+  +L+  P QR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>92</Hit_num>
  <Hit_id>YDR247W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:956013:957398:1 gene:YDR247W transcript:YDR247W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VHS1 description:Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; VHS1 has a paralog, SKS1, that arose from the whole genome duplication [Source:SGD;Acc:S000002655]</Hit_def>
  <Hit_accession>YDR247W</Hit_accession>
  <Hit_len>461</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>4.29375e-11</Hsp_evalue>
      <Hsp_query-from>790</Hsp_query-from>
      <Hsp_query-to>1215</Hsp_query-to>
      <Hsp_hit-from>168</Hsp_hit-from>
      <Hsp_hit-to>325</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>166</Hsp_align-len>
      <Hsp_qseq>QIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSS----------------DLWALGCIIYQLVAGLPPFRAP-----NEYLIFQK---IIKLEYEFPEKFFPKAKDLVEKLLVSDPMQRLGCDE</Hsp_qseq>
      <Hsp_hseq>QICSALNYCHEHGIYHCDIKPENLLLDTEDNVFLCDFG----LSTTSTYIKPNVCIGSSYYMPPERISFDGRVSSSKSGGHKLGKVCPSCNGDLWSLGIILINLTCIRNPWLKADKTEDNTYYYFTKDPNILKQILPLSDDFYS----LLSKILQVNPKNRMSLQE</Hsp_hseq>
      <Hsp_midline>QI S+L + H  GI H D+KPEN+LL+ + ++ + DFG    LS  S + + N  +G++ Y+ PE ++      SS                DLW+LG I+  L     P+        N Y  F K   I+K      + F+     L+ K+L  +P  R+   E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>93</Hit_num>
  <Hit_id>YNL020C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:595623:597539:-1 gene:YNL020C transcript:YNL020C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ARK1 description:Serine/threonine protein kinase; involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis; ARK1 has a paralog, PRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004965]</Hit_def>
  <Hit_accession>YNL020C</Hit_accession>
  <Hit_len>638</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>5.4487e-11</Hsp_evalue>
      <Hsp_query-from>787</Hsp_query-from>
      <Hsp_query-to>1200</Hsp_query-to>
      <Hsp_hit-from>139</Hsp_hit-from>
      <Hsp_hit-to>286</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>150</Hsp_align-len>
      <Hsp_qseq>AQIVSSLEHLHSLG--IIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFV-------GTAQYVSPELLTEKSAC---KSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEKFFPKAKDLVEKLLVSDPMQR</Hsp_qseq>
      <Hsp_hseq>SQVTQGVAAMHALQPPLIHRDIKIENVLISANNEYKLCDFGSVCGIIRPPRNSQELSYVQQDILKNTTAQYRSPEMIDTFRGLPIDEKSDIWALGIFLYKLCYYTTPFEKGGDLAILSG--KFEFPLYPNYSEQLKGLIRDILVQDPRHR</Hsp_hseq>
      <Hsp_midline>+Q+   +  +H+L   +IHRD+K EN+L++ +   ++ DFG+   +    ++++  S+V        TAQY SPE++         + SD+WALG  +Y+L     PF    +  I     K E+     +  + K L+  +LV DP  R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>94</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>8.13534e-11</Hsp_evalue>
      <Hsp_query-from>613</Hsp_query-from>
      <Hsp_query-to>1266</Hsp_query-to>
      <Hsp_hit-from>206</Hsp_hit-from>
      <Hsp_hit-to>413</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>225</Hsp_align-len>
      <Hsp_qseq>REKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKH-----RSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHA-RANSFVGTAQYVSPELLT-EKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFPEKFFPKAKDLVEKLLVSDPMQRLGCDECGGYPPLKSHPFFSEIS</Hsp_qseq>
      <Hsp_hseq>REMALCRELHNKHLTTLVEIFLERKCVHMVYEYAEH-DLLQIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDGCVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELIGLQPIFKGEEAKLDSKKTV-----------PFQVNQLQRIL-----EVLGTPDQKIWPYLEKYPEYDQIT</Hsp_hseq>
      <Hsp_midline>RE  +   L++     L   F + + ++    YA++ ++L+ I  H     R       R    Q++  + +LH   ++HRDLKP NI++  D  ++I D G A+   +  +     +  V T  Y +PELL   +    + DLW++GCI  +L+   P F+     L  +K +           P   + ++++L     + LG  +   +P L+ +P + +I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>95</Hit_num>
  <Hit_id>YBR059C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:356861:360187:-1 gene:YBR059C transcript:YBR059C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AKL1 description:Ser-Thr protein kinase; member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization [Source:SGD;Acc:S000000263]</Hit_def>
  <Hit_accession>YBR059C</Hit_accession>
  <Hit_len>1108</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>9.65792e-11</Hsp_evalue>
      <Hsp_query-from>718</Hsp_query-from>
      <Hsp_query-to>1200</Hsp_query-to>
      <Hsp_hit-from>136</Hsp_hit-from>
      <Hsp_hit-to>307</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>182</Hsp_align-len>
      <Hsp_qseq>NGEMLKYIRKHRSFDENCTRFYSAQIVS-------SLEHLHSL--GIIHRDLKPENILLNEDMHIQITDFGTAK----ILSDNSKHA--RANSFVGTA-QYVSPELLTEKSAC----KSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKIIKLEYEFP-EKFFPKAKDLVEKLLVSDPMQR</Hsp_qseq>
      <Hsp_hseq>NKSLLDYMNQRLS-----TKLTEAEIVKIMYDVALSISQMHYLPVSLIHRDIKIENVLVDAKNNFKLADFGSTSTCFPIVTTHQDIALLTQNIYVHTTPQYRSPEMI-DLYRCLPINEKSDIWALGVFLYKLLFFTTPFEMTGQFAILHS----KYEFPVNKYSSKLINLIIIMLAENPNLR</Hsp_hseq>
      <Hsp_midline>N  +L Y+ +  S     T+   A+IV        S+  +H L   +IHRD+K EN+L++   + ++ DFG+      I++ +   A    N +V T  QY SPE++ +   C    + SD+WALG  +Y+L+    PF    ++ I       +YEFP  K+  K  +L+  +L  +P  R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>96</Hit_num>
  <Hit_id>YPL026C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:500675:502183:-1 gene:YPL026C transcript:YPL026C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKS1 description:Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway; SKS1 has a paralog, VHS1, that arose from the whole genome duplication [Source:SGD;Acc:S000005947]</Hit_def>
  <Hit_accession>YPL026C</Hit_accession>
  <Hit_len>502</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>1.36909e-10</Hsp_evalue>
      <Hsp_query-from>790</Hsp_query-from>
      <Hsp_query-to>1074</Hsp_query-to>
      <Hsp_hit-from>169</Hsp_hit-from>
      <Hsp_hit-to>275</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>111</Hsp_align-len>
      <Hsp_qseq>QIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELL----------TEKSACKSS------DLWALGCIIYQLVAGLPPF</Hsp_qseq>
      <Hsp_hseq>QLCSALDHCHRLGIYHCDIKPENVLLDRNDNAYLCDFG----LSTKSKYLAPNVCVGSSYYMAPERILYCLNTTTNGIHVDECCSSLPTDTGDIWSLGIILINLTCIRNPW</Hsp_hseq>
      <Hsp_midline>Q+ S+L+H H LGI H D+KPEN+LL+ + +  + DFG    LS  SK+   N  VG++ Y++PE +               C SS      D+W+LG I+  L     P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>97</Hit_num>
  <Hit_id>YNL154C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:343636:345276:-1 gene:YNL154C transcript:YNL154C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YCK2 description:Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform; shares redundant functions with Yck1p in morphogenesis, proper septin assembly, endocytic trafficking, and glucose sensing; stabilized by Sod1p binding in the presence of glucose and oxygen, causing glucose repression of respiratory metabolism; involved in the phosphorylation and regulation of glucose sensor Rgt2p; YCK2 has a paralog, YCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005098]</Hit_def>
  <Hit_accession>YNL154C</Hit_accession>
  <Hit_len>546</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>1.14878e-09</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>1110</Hsp_query-to>
      <Hsp_hit-from>76</Hsp_hit-from>
      <Hsp_hit-to>297</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>228</Hsp_align-len>
      <Hsp_qseq>FKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKH--RSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLN-----EDMHIQITDFGTAKILSD-----NSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPF---RAPNEYLIFQKI</Hsp_qseq>
      <Hsp_hseq>YKIGKKIGEGSFGVLFEGTNMINGLPVAIKFEPRKTEAPQLKDEY--RTYKILAGT--PGIPQEYYFGQ--EGLHNILVIDLLGPSLEDLFDWCGRRFSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANKVHLIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEAMGHVFFYFLRGQLPWQGLKAPNNKQKYEKI</Hsp_hseq>
      <Hsp_midline>+K GK +GEGSF  +     +  G   AIK   ++    + K  Y  R  ++L+    P   + ++  Q  E L+  L     G  L+ +     R F        + Q+++ +E LH+  +I+RD+KP+N L+      +   + + DFG AK   D     +  +    S  GTA+Y+S      +   +  D+ A+G + +  + G  P+   +APN    ++KI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>98</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.5362</Hsp_bit-score>
      <Hsp_score>140</Hsp_score>
      <Hsp_evalue>7.79516e-09</Hsp_evalue>
      <Hsp_query-from>466</Hsp_query-from>
      <Hsp_query-to>1065</Hsp_query-to>
      <Hsp_hit-from>442</Hsp_hit-from>
      <Hsp_hit-to>650</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>213</Hsp_align-len>
      <Hsp_qseq>EDFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEK------RHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYI------RKHRSFDENCTRFYSAQIVSSLEHLH-SLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGL</Hsp_qseq>
      <Hsp_hseq>EKFTNVHSIGKGQFSTVYQVTFAQTNKKYAIKAIKPNKYNSLKRILLEIKILNEVTNQITMDQEGKEYIIDYISSWKFQNSYYIMTELCENGNLDGFLQEQVIAKKKRLEDWRIWKII-VELSLALRFIHDSCHIVHLDLKPANVMITFEGNLKLGDFGMATHLPLEDKSFENE---GDREYIAPEIISDCTYDYKADIFSLGLMIVEIAANV</Hsp_hseq>
      <Hsp_midline>E F     +G+G FSTV       T K+YAIK ++       + I+ E K+      +  + +    + +    +++ +   Y      +NG +  ++      +K R  D    +    ++  +L  +H S  I+H DLKP N+++  + ++++ DFG A  L    K        G  +Y++PE++++ +    +D+++LG +I ++ A +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>99</Hit_num>
  <Hit_id>YGR188C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:872044:875109:-1 gene:YGR188C transcript:YGR188C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BUB1 description:Protein kinase involved in the cell cycle checkpoint into anaphase; in complex with Mad1p and Bub3p, prevents progression into anaphase in presence of spindle damage; Cdc28p-mediated phosphorylation at Bub1p-T566 is important for degradation in anaphase and adaptation of checkpoint to prolonged mitotic arrest; associates with centromere DNA via Skp1p; involved in Sgo1p relocalization in response to sister kinetochore tension; paralog MAD3 arose from whole genome duplication [Source:SGD;Acc:S000003420]</Hit_def>
  <Hit_accession>YGR188C</Hit_accession>
  <Hit_len>1021</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>1.18936e-07</Hsp_evalue>
      <Hsp_query-from>490</Hsp_query-from>
      <Hsp_query-to>867</Hsp_query-to>
      <Hsp_hit-from>711</Hsp_hit-from>
      <Hsp_hit-to>841</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>138</Hsp_align-len>
      <Hsp_qseq>LGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKE----KKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRS--------FDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILL</Hsp_qseq>
      <Hsp_hseq>LGEGGYATVYLA-ESSQGHLRALKV-EKPASVWEYYIMSQVEFRLRKSTILKSIINASALHLFL---DES--YLVLNYASQGTVLDLINLQREKAIDGNGIMDEYLCMFITVELMKVLEKIHEVGIIHGDLKPDNCMI</Hsp_hseq>
      <Hsp_midline>LGEG ++TV LA E + G   A+K+ EK   + E     +V +  R+  +L  + +   + LF    DE   Y  L+YA  G +L  I   R          DE    F + +++  LE +H +GIIH DLKP+N ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>100</Hit_num>
  <Hit_id>YKL171W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:127475:130261:1 gene:YKL171W transcript:YKL171W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NNK1 description:Protein kinase; implicated in proteasome function; interacts with TORC1, Ure2 and Gdh2; overexpression leads to hypersensitivity to rapamycin and nuclear accumulation of Gln3; epitope-tagged protein localizes to the cytoplasm [Source:SGD;Acc:S000001654]</Hit_def>
  <Hit_accession>YKL171W</Hit_accession>
  <Hit_len>928</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>1.35928e-07</Hsp_evalue>
      <Hsp_query-from>460</Hsp_query-from>
      <Hsp_query-to>909</Hsp_query-to>
      <Hsp_hit-from>438</Hsp_hit-from>
      <Hsp_hit-to>607</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>RPED-------FKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLF-FTFQDEEKLYFGLSYAKNGEMLKYI-------RKHRSFDENC--TRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNE-----DMHIQITDFGTA</Hsp_qseq>
      <Hsp_hseq>RPDDKGMEILGHRLGKIIGFGAWGIIRECFDIETGVGRVIKIVKFKGHQNIKK--HVLREVAIWRTLKHNRILPLLDWKLDDNYAMYCLTERINDGTLYDLVISWDEFKRSKIPFAERCRLTIFLSLQLLSALKYMHSKTIVHGDIKLENCLLQKEGKKSDWKVFLCDFGMS</Hsp_hseq>
      <Hsp_midline>RP+D        + GKI+G G++  +    ++ TG    IKI++ +     KK  +V RE  +   L H   + L  +   D   +Y       +G +   +       R    F E C  T F S Q++S+L+++HS  I+H D+K EN LL +     D  + + DFG +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>101</Hit_num>
  <Hit_id>YJL165C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:106894:109461:-1 gene:YJL165C transcript:YJL165C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HAL5 description:Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters; HAL5 has a paralog, KKQ8, that arose from the whole genome duplication [Source:SGD;Acc:S000003701]</Hit_def>
  <Hit_accession>YJL165C</Hit_accession>
  <Hit_len>855</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>1.7968e-07</Hsp_evalue>
      <Hsp_query-from>781</Hsp_query-from>
      <Hsp_query-to>1209</Hsp_query-to>
      <Hsp_hit-from>668</Hsp_hit-from>
      <Hsp_hit-to>842</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>175</Hsp_align-len>
      <Hsp_qseq>YSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDN-SKHARANS-FVGTAQYVSPELLTEKSAC--KSSDLWALGCIIYQLVAG------------------LPPFRAPNEYLIFQKIIKLEYEFPE----------KFFPKAKDLVEKLLVSDPMQRLGC</Hsp_qseq>
      <Hsp_hseq>FMKQLLNGVQYMHDHGIAHCDLKPENILFQPNGLLKICDFGTSSVFQTAWEKHVHFQSGAMGSEPYVAPEEFIRDAEYDPRLVDCWSCGIVYCTMVMGQYLWKIAIPEKDSLFKSFLSEIKDDGQFYLFEELRHVSSELNRLRKIALYRTFQVDPTKRITIEQLLQSSWMRKTKC</Hsp_hseq>
      <Hsp_midline>+  Q+++ ++++H  GI H DLKPENIL   +  ++I DFGT+ +      KH    S  +G+  YV+PE     +    +  D W+ G +   +V G                  L   +   ++ +F+++  +  E             +  P  +  +E+LL S  M++  C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>102</Hit_num>
  <Hit_id>YPL236C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:101608:102702:-1 gene:YPL236C transcript:YPL236C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ENV7 description:Vacuolar membrane protein kinase; negatively regulates membrane fusion; associates with vacuolar membrane through palmitoylation of one or more cysteines in consensus sequence; vacuolar membrane association is essential to its kinase activity; mutant shows defect in CPY processing; ortholog of human serine/threonine kinase 16 (STK16) [Source:SGD;Acc:S000006157]</Hit_def>
  <Hit_accession>YPL236C</Hit_accession>
  <Hit_len>364</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>2.83714e-07</Hsp_evalue>
      <Hsp_query-from>820</Hsp_query-from>
      <Hsp_query-to>1200</Hsp_query-to>
      <Hsp_hit-from>208</Hsp_hit-from>
      <Hsp_hit-to>349</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>SLGIIHRDLKPENILLNEDMHIQITDFGT---AKILSDNSKH-ARANSFVG---TAQYVSPELLTEK---SACKSSDLWALGCIIYQLVAGLPPFRAPNEY---LIFQKIIKLEYEFP--EKFFPKAKDLVEKLLVSDPMQR</Hsp_qseq>
      <Hsp_hseq>SIAYAHRDITPSNILFSSDGLPVIGDLGSCSQADITIENRHQLSELQEWVNDNCTLPYTPPELLNLKLNQVLSSKVDIWSLGCTFYTLMFGISPFEREEQIHGASLTYAINTGKYSFPRNSRFSEGLLSVIKKCIQVDPIQR</Hsp_hseq>
      <Hsp_midline>S+   HRD+ P NIL + D    I D G+   A I  +N    +    +V    T  Y  PELL  K         D+W+LGC  Y L+ G+ PF    +     +   I   +Y FP   +F      +++K +  DP+QR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>103</Hit_num>
  <Hit_id>YBR097W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:436951:441315:1 gene:YBR097W transcript:YBR097W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VPS15 description:Serine/threonine protein kinase involved in vacuolar protein sorting; functions as a membrane-associated complex with Vps34p; active form recruits Vps34p to the Golgi membrane; interacts with the GDP-bound form of Gpa1p; myristoylated; a fraction is localized, with Vps34p, to nuclear pores at nucleus-vacuole junctions and may facilitate transcription elongation for genes positioned at the nuclear periphery [Source:SGD;Acc:S000000301]</Hit_def>
  <Hit_accession>YBR097W</Hit_accession>
  <Hit_len>1454</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>3.0374e-07</Hsp_evalue>
      <Hsp_query-from>775</Hsp_query-from>
      <Hsp_query-to>1215</Hsp_query-to>
      <Hsp_hit-from>125</Hsp_hit-from>
      <Hsp_hit-to>290</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>174</Hsp_align-len>
      <Hsp_qseq>RFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDF--------------GTAKILSDNSKHARANSFVGTAQYVSPELLTEK----------SACKSSDLWALGCIIYQLVA-GLPPFRAPN--EYLIFQKIIKLEYEFPEKFFPKAKDLVEKLLVSDPMQRLGCDE</Hsp_qseq>
      <Hsp_hseq>KFIAFQLLNALKDIHNLNIVHGDIKTENILVTSWNWCILTDFAAFIKPVYLPEDNPGEFLFYFDTSKRRTC--------YLAPERFNSKLYQDGKSNNGRLTKEMDIFSLGCVIAEIFAEGRPIFNLSQLFKYKSNSYDVNREFLMEEMNSTDLRNLVLDMIQLDPSKRLSCDE</Hsp_hseq>
      <Hsp_midline>+F + Q++++L+ +H+L I+H D+K ENIL+       +TDF              G      D SK            Y++PE    K             K  D+++LGC+I ++ A G P F      +Y      +  E+   E      ++LV  ++  DP +RL CDE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>104</Hit_num>
  <Hit_id>YKL198C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:68232:70220:-1 gene:YKL198C transcript:YKL198C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK1 description:Putative serine/threonine protein kinase; regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein; PTK1 has a paralog, PTK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001681]</Hit_def>
  <Hit_accession>YKL198C</Hit_accession>
  <Hit_len>662</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>3.86746e-07</Hsp_evalue>
      <Hsp_query-from>790</Hsp_query-from>
      <Hsp_query-to>1074</Hsp_query-to>
      <Hsp_hit-from>312</Hsp_hit-from>
      <Hsp_hit-to>423</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>112</Hsp_align-len>
      <Hsp_qseq>QIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDN-----SKHARANSFVGTAQYVSPELLTEKSA------------CKSSDLWALGCIIYQLVAGLPPF</Hsp_qseq>
      <Hsp_hseq>QVACGVKFCHDQGIAHRDLKPENVLLSPDGVCKLTDFGISDWYHTDPHDLSSPVKKCAGMIGSPPYAPPEVMFYDSKKHYDTELQQPYDPRALDCYGLGIILMTLVNNVIPF</Hsp_hseq>
      <Hsp_midline>Q+   ++  H  GI HRDLKPEN+LL+ D   ++TDFG +     +     S   +    +G+  Y  PE++   S              ++ D + LG I+  LV  + PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>105</Hit_num>
  <Hit_id>YKL168C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:131288:133462:-1 gene:YKL168C transcript:YKL168C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KKQ8 description:Putative serine/threonine protein kinase with unknown cellular role; KKQ8 has a paralog, HAL5, that arose from the whole genome duplication [Source:SGD;Acc:S000001651]</Hit_def>
  <Hit_accession>YKL168C</Hit_accession>
  <Hit_len>724</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>1.10502e-06</Hsp_evalue>
      <Hsp_query-from>781</Hsp_query-from>
      <Hsp_query-to>1062</Hsp_query-to>
      <Hsp_hit-from>543</Hsp_hit-from>
      <Hsp_hit-to>640</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>99</Hsp_align-len>
      <Hsp_qseq>YSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILS---DNSKHARANSFVGTAQYVSPELLT--EKSACKSSDLWALGCIIYQLVAG</Hsp_qseq>
      <Hsp_hseq>FMKQLLHGVKFMHDHGIAHCDLKPENILFYPHGLLKICDFGTSSVFQTAWERRVHAQ-KGIIGSEPYVAPEEFVDGEYYDPRLIDCWSCGVVYITMILG</Hsp_hseq>
      <Hsp_midline>+  Q++  ++ +H  GI H DLKPENIL      ++I DFGT+ +     +   HA+    +G+  YV+PE     E    +  D W+ G +   ++ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>106</Hit_num>
  <Hit_id>YMR216C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:698811:701039:-1 gene:YMR216C transcript:YMR216C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKY1 description:SR protein kinase (SRPK); involved in regulating proteins involved in mRNA metabolism and cation homeostasis; similar to human SRPK1 [Source:SGD;Acc:S000004829]</Hit_def>
  <Hit_accession>YMR216C</Hit_accession>
  <Hit_len>742</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>1.62077e-06</Hsp_evalue>
      <Hsp_query-from>490</Hsp_query-from>
      <Hsp_query-to>867</Hsp_query-to>
      <Hsp_hit-from>164</Hsp_hit-from>
      <Hsp_hit-to>302</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>139</Hsp_align-len>
      <Hsp_qseq>LGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKE---------KKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGE-MLKYIRK--HRSFDENCTRFYSAQIVSSLEHLHS-LGIIHRDLKPENILL</Hsp_qseq>
      <Hsp_hseq>LGWGHFSTVWLAKDMVNNTHVAMKIVRGDKVYTEAAEDEIKLLQRVNDADNTKEDSMGANHILKLLDHFNHKGPNGVHVVMVFEVLGENLLALIKKYEHRGIPLIYVKQISKQLLLGLDYMHRRCGIIHTDIKPENVLM</Hsp_hseq>
      <Hsp_midline>LG G FSTV LAK++      A+KI+    +  E         ++V   +  KE     NH   +   F  +    ++  + +   GE +L  I+K  HR       +  S Q++  L+++H   GIIH D+KPEN+L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>107</Hit_num>
  <Hit_id>YER123W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:404813:406387:1 gene:YER123W transcript:YER123W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YCK3 description:Palmitoylated vacuolar membrane-localized casein kinase I isoform; negatively regulates vacuole fusion during hypertonic stress via phosphorylation of Vps41p; shares essential functions with Hrr25p; regulates vesicle fusion in AP-3 pathway [Source:SGD;Acc:S000000925]</Hit_def>
  <Hit_accession>YER123W</Hit_accession>
  <Hit_len>524</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>1.87174e-06</Hsp_evalue>
      <Hsp_query-from>751</Hsp_query-from>
      <Hsp_query-to>1110</Hsp_query-to>
      <Hsp_hit-from>120</Hsp_hit-from>
      <Hsp_hit-to>268</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>149</Hsp_align-len>
      <Hsp_qseq>RSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILL---------------------NEDMHIQITDFGTAKILSD-----NSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPF---RAPNEYLIFQKI</Hsp_qseq>
      <Hsp_hseq>RKFSVKTTCMVAKQMIDRVRAIHDHDLIYRDIKPDNFLISQYQRISPEGKVIKSCASSSNNDPNLIYMVDFGMAKQYRDPRTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKAPNNKLKYEKI</Hsp_hseq>
      <Hsp_midline>R F    T   + Q++  +  +H   +I+RD+KP+N L+                     N+   I + DFG AK   D     +  +    S  GTA+Y+S      +   +  DL +LG + +  + G  P+   +APN  L ++KI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3253092752</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053984-RA transcript Note:&quot;Similar to Tardbp TAR DNA-binding protein 43 (Mus musculus)&quot; offset:133 AED:0.28 eAED:0.28 QI:133|0.66|1|1|1|1|4|1128|429</Iteration_query-def>
  <Iteration_query-len>2551</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YOL123W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:87844:89448:1 gene:YOL123W transcript:YOL123W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRP1 description:Subunit of cleavage factor I; cleavage factor I is a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3&apos; ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences; required for genome stability [Source:SGD;Acc:S000005483]</Hit_def>
  <Hit_accession>YOL123W</Hit_accession>
  <Hit_len>534</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>9.95791e-09</Hsp_evalue>
      <Hsp_query-from>452</Hsp_query-from>
      <Hsp_query-to>664</Hsp_query-to>
      <Hsp_hit-from>161</Hsp_hit-from>
      <Hsp_hit-to>231</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>42</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>71</Hsp_align-len>
      <Hsp_qseq>LIVLGLPWKCNEQDLRDYFTEVGDVLMVQVKRDAKSGTSKGFGFVRFSEFESQLKAISQRHLIGGRWCDVK</Hsp_qseq>
      <Hsp_hseq>MFIGGLNWDTTEDNLREYFGKYGTVTDLKIMKDPATGRSRGFGFLSFEKPSSVDEVVKTQHILDGKVIDPK</Hsp_hseq>
      <Hsp_midline>+ + GL W   E +LR+YF + G V  +++ +D  +G S+GFGF+ F +  S  + +  +H++ G+  D K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YER165W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:510373:512106:1 gene:YER165W transcript:YER165W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PAB1 description:Poly(A) binding protein; part of the 3&apos;-end RNA-processing complex, mediates interactions between the 5&apos; cap structure and the 3&apos; mRNA poly(A) tail, involved in control of poly(A) tail length, interacts with translation factor eIF-4G; stimulates, but is not required for the deadenylation activity of the Pan2p-Pan3p poly(A)-ribonuclease complex [Source:SGD;Acc:S000000967]</Hit_def>
  <Hit_accession>YER165W</Hit_accession>
  <Hit_len>577</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.3654</Hsp_bit-score>
      <Hsp_score>111</Hsp_score>
      <Hsp_evalue>8.49915e-06</Hsp_evalue>
      <Hsp_query-from>428</Hsp_query-from>
      <Hsp_query-to>661</Hsp_query-to>
      <Hsp_hit-from>31</Hsp_hit-from>
      <Hsp_hit-to>111</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>81</Hsp_align-len>
      <Hsp_qseq>RSVQKTSDLIVLG-LPWKCNEQDLRDYFTEVGDVLMVQVKRDAKSGTSKGFGFVRFSEFESQLKAISQRHL--IGGRWCDV</Hsp_qseq>
      <Hsp_hseq>QSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRI</Hsp_hseq>
      <Hsp_midline>+SV+ +S  + +G L    +E  L D F+ +G V  ++V RDA + TS G+ +V F++ E+  KAI Q +   I GR C +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1704984784</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053986-RA transcript Note:&quot;Similar to Ap4m1 AP-4 complex subunit mu-1 (Rattus norvegicus)&quot; offset:54 AED:0.04 eAED:0.04 QI:54|0.9|0.90|1|0|0|11|1389|351</Iteration_query-def>
  <Iteration_query-len>2499</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YPL259C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:51244:52671:-1 gene:YPL259C transcript:YPL259C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:APM1 description:Mu1-like medium subunit of the AP-1 complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting; the AP-1 complex is the clathrin-associated protein complex [Source:SGD;Acc:S000006180]</Hit_def>
  <Hit_accession>YPL259C</Hit_accession>
  <Hit_len>475</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.5893</Hsp_bit-score>
      <Hsp_score>231</Hsp_score>
      <Hsp_evalue>1.86115e-20</Hsp_evalue>
      <Hsp_query-from>97</Hsp_query-from>
      <Hsp_query-to>1107</Hsp_query-to>
      <Hsp_hit-from>52</Hsp_hit-from>
      <Hsp_hit-to>474</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>98</Hsp_identity>
      <Hsp_positive>174</Hsp_positive>
      <Hsp_gaps>118</Hsp_gaps>
      <Hsp_align-len>439</Hsp_align-len>
      <Hsp_qseq>HDGLCYVHMRHNGLYF-GLTCKPQASPFILIQFLNRFAAIVKDYCGSVSEEAIRQNXXXXXXXXXXXXDFGVVQTTRLDVLRNYVQSEAVNTQPSSLFDMSTIGLFGADTQQKTLVPASASIRSLSHQSKTNEIFVDVLERLTVLIGANGNVVQAELNGDINLKSFVNGCSEIFMTFN----------HDLAI---------------------GSSQNRGYGGAVRLDECRFHANVNVTDFETKRAIRVSPGPG--------------------------------------------------EVMLALSRDVSSP-----DQTATLEPDSSSVVWNVPRITGGSQLSAIFRLEVPGLR---------PSARLEV--GPVALTFDLPSLAMSGLRIGCLR---PTLGGRGGAALSGEPPKRWLRYSTSSG-SYVVRI</Hsp_qseq>
      <Hsp_hseq>HNGLEYLFIQHNDLYVVAIVTSLSANAAAIFTFLHKLVEVLSDYLKTVEEESIRDNFVIIYELLDEVMDYGIPQITETKMLKQYI------TQKSFKLVKSAKKKRNA-TRPPVALTNSVSWRPEGITHKKNEAFLDIVESINMLMTQKGQVLRSEIIGDVKVNSKLSGMPDLKLGINDKGIFSKYLDDDTNIPSASATTSDNNTETDKKPSITSSSATNKKKVNIELEDLKFHQCVRLSKFENEKIITFIPPDGKFDLMNYRLSTTIKPLIWCDVNVQVHSNSRIEIHCKAKAQIKRKSTATNVEILIPVPDDADTPTFKYSHGSLKYVPEKSAILWKIRSFPGGKEYSMSAELGLPSISNNEDGNRTMPKSNAEILKGPVQIKFQIPYFTTSGIQVRYLKINEPKLQYKSYP---------WVRYITQSGDDYTIRL</Hsp_hseq>
      <Hsp_midline>H+GL Y+ ++HN LY   +     A+   +  FL++   ++ DY  +V EE+IR N  ++YELL+E++D+G+ Q T   +L+ Y+      TQ S     S      A T+    +  S S R      K NE F+D++E + +L+   G V+++E+ GD+ + S ++G  ++ +  N           D  I                      SS        + L++ +FH  V ++ FE ++ I   P  G                                                  E+++ +  D  +P       +    P+ S+++W +    GG + S    L +P +          P +  E+  GPV + F +P    SG+++  L+   P L  +            W+RY T SG  Y +R+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YNL202W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:259578:260456:1 gene:YNL202W transcript:YNL202W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS19 description:Peroxisomal 2,4-dienoyl-CoA reductase; auxiliary enzyme of fatty acid beta-oxidation; homodimeric enzyme required for growth and sporulation on petroselineate medium; expression induced during late sporulation and in the presence of oleate [Source:SGD;Acc:S000005146]</Hit_def>
  <Hit_accession>YNL202W</Hit_accession>
  <Hit_len>292</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>3.11008e-07</Hsp_evalue>
      <Hsp_query-from>2183</Hsp_query-from>
      <Hsp_query-to>2317</Hsp_query-to>
      <Hsp_hit-from>225</Hsp_hit-from>
      <Hsp_hit-to>269</Hsp_hit-to>
      <Hsp_query-frame>-3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>29</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>45</Hsp_align-len>
      <Hsp_qseq>QNPFASVPLGRAGTKTDVAHCALFLASPLASYVTGSTLVADGGAW</Hsp_qseq>
      <Hsp_hseq>EKALAKIPLQRLGSTRDIAESTVYIFSPAASYVTGTVLVVDGGMW</Hsp_hseq>
      <Hsp_midline>+   A +PL R G+  D+A   +++ SP ASYVTG+ LV DGG W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1666441245</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0053988-RA transcript Note:&quot;Similar to CAPN15 Calpain-15 (Homo sapiens)&quot; offset:0 AED:0.17 eAED:0.17 QI:0|0.55|0.6|0.9|1|1|10|3712|586</Iteration_query-def>
  <Iteration_query-len>5473</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>104</Statistics_hsp-len>
      <Statistics_eff-space>3831587240</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0016975-RA transcript Note:&quot;Similar to PSMC2 26S proteasome regulatory subunit 7 (Macaca fascicularis)&quot; offset:0 AED:0.18 eAED:0.19 QI:0|0|0|1|0.5|0.66|3|340|378</Iteration_query-def>
  <Iteration_query-len>1477</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YKL145W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:174213:175616:1 gene:YKL145W transcript:YKL145W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RPT1 description:ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; required for optimal CDC20 transcription; interacts with Rpn12p and Ubr1p; mutant has aneuploidy tolerance [Source:SGD;Acc:S000001628]</Hit_def>
  <Hit_accession>YKL145W</Hit_accession>
  <Hit_len>467</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>530.791</Hsp_bit-score>
      <Hsp_score>1366</Hsp_score>
      <Hsp_evalue>0</Hsp_evalue>
      <Hsp_query-from>181</Hsp_query-from>
      <Hsp_query-to>1134</Hsp_query-to>
      <Hsp_hit-from>145</Hsp_hit-from>
      <Hsp_hit-to>467</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>269</Hsp_identity>
      <Hsp_positive>299</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>323</Hsp_align-len>
      <Hsp_qseq>YIINVKQFAKFVVDLGDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDP-----TVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXXXXXNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFGLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKVATEKDFLEAVNKVIKSYAKFSATPRYMTYN</Hsp_qseq>
      <Hsp_hseq>YVINLKQIAKFVVGLGERVSPTDIEEGMRVGVDRSKYNIELPLPPRIDPSVTMMTVEEKPDVTYSDVGGCKDQIEKLREVVELPLLSPERFATLGIDPPKGILLYGPPGTGKTLCARAVANRTDATFIRVIGSELVQKYVGEGARMVRELFEMARTKKACIIFFDEIDAVGGARFDDGAGGDNEVQRTMLELITQLDGFDPRGNIKVMFATNRPNTLDPALLRPGRIDRKVEFSLPDLEGRANIFRIHSKSMSVERGIRWELISRLCPNSTGAELRSVCTEAGMFAIRARRKVATEKDFLKAVDKVISGYKKFSSTSRYMQYN</Hsp_hseq>
      <Hsp_midline>Y+IN+KQ AKFVV LG++V+PTDIEEGMRVGVDR+KY I +PLPP+IDP     TVEEKPDVTYSDVGGCK+QIEKLREVVE PLL PERF  LGI+PPKG+LL+GPPGTGKTLCARAVANRTDA FIRVIGSELVQKYVGEGARMVRELFEMARTKKAC+IFFDEIDA+GGARFDDGAGGDNEVQRTMLELI QLDGFDPRGNIKV+ ATNRP+TLDPAL+RPGR+DRK+EF LPDLEGR +IF+IH++SMSVER IR+EL++RLCPNSTGAE+RSVCTEAGMFAIRARRKVATEKDFL+AV+KVI  Y KFS+T RYM YN</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YGL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:410069:411286:-1 gene:YGL048C transcript:YGL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RPT6 description:ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; bound by ubiquitin-protein ligases Ubr1p and Ufd4p; localized mainly to the nucleus throughout the cell cycle; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003016]</Hit_def>
  <Hit_accession>YGL048C</Hit_accession>
  <Hit_len>405</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>303.908</Hsp_bit-score>
      <Hsp_score>777</Hsp_score>
      <Hsp_evalue>1.04627e-99</Hsp_evalue>
      <Hsp_query-from>169</Hsp_query-from>
      <Hsp_query-to>1086</Hsp_query-to>
      <Hsp_hit-from>80</Hsp_hit-from>
      <Hsp_hit-to>390</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>161</Hsp_identity>
      <Hsp_positive>216</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>311</Hsp_align-len>
      <Hsp_qseq>AEEDYIINVKQFAKFVVDLGDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDP-----TVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXXXXXNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFGLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKVATEKDFLEAVNKVI</Hsp_qseq>
      <Hsp_hseq>SDKKVLVKVQPEGKYIVDVAKDINVKDLKASQRVCLRSDSYMLHKVLENKADPLVSLMMVEKVPDSTYDMVGGLTKQIKEIKEVIELPVKHPELFESLGIAQPKGVILYGPPGTGKTLLARAVAHHTDCKFIRVSGAELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRVEGSGGGDSEVQRTMLELLNQLDGFETSKNIKIIMATNRLDILDPALLRPGRIDRKIEFPPPSVAARAEILRIHSRKMNLTRGINLRKVAEKMNGCSGADVKGVCTEAGMYALRERRIHVTQEDFELAVGKVM</Hsp_hseq>
      <Hsp_midline>+++  ++ V+   K++VD+   +   D++   RV +  + Y +H  L  K DP      VE+ PD TY  VGG  +QI++++EV+E P+ HPE F +LGI  PKGV+L+GPPGTGKTL ARAVA+ TD  FIRV G+ELVQKY+GEG+RMVRELF MAR     +IF DEID+IG  R +   GGD+EVQRTMLEL+NQLDGF+   NIK++MATNR D LDPAL+RPGR+DRKIEF  P +  R  I +IH+R M++ R I    +A      +GA+++ VCTEAGM+A+R RR   T++DF  AV KV+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YOR259C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:812395:813708:-1 gene:YOR259C transcript:YOR259C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RPT4 description:ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in degradation of ubiquitinated substrates; contributes preferentially to ERAD; required for spindle pole body duplication; mainly nuclear localization [Source:SGD;Acc:S000005785]</Hit_def>
  <Hit_accession>YOR259C</Hit_accession>
  <Hit_len>437</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>275.404</Hsp_bit-score>
      <Hsp_score>703</Hsp_score>
      <Hsp_evalue>3.59615e-88</Hsp_evalue>
      <Hsp_query-from>106</Hsp_query-from>
      <Hsp_query-to>1083</Hsp_query-to>
      <Hsp_hit-from>92</Hsp_hit-from>
      <Hsp_hit-to>422</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>154</Hsp_identity>
      <Hsp_positive>212</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>331</Hsp_align-len>
      <Hsp_qseq>EGDIALLKTYGQSAYSRLTKQAEEDYIINVKQFAKFVVDLGDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVE-----EKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXXXXXNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFGLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKVATEKDFLEAVNKV</Hsp_qseq>
      <Hsp_hseq>ENDIKALQSIGQLIGEVMKELSEEKYIVKASSGPRYIVGVRNSVDRSKLKKGVRVTLDITTLTIMRILPRETDPLVYNMTSFEQGEITFDGIGGLTEQIRELREVIELPLKNPEIFQRVGIKPPKGVLLYGPPGTGKTLLAKAVAATIGANFIFSPASGIVDKYIGESARIIREMFAYAKEHEPCIIFMDEVDAIGGRRFSEGTSADREIQRTLMELLTQMDGFDNLGQTKIIMATNRPDTLDPALLRPGRLDRKVEIPLPNEAGRLEIFKIHTAKVKKTGEFDFEAAVKMSDGFNGADIRNCATEAGFFAIRDDRDHINPDDLMKAVRKV</Hsp_hseq>
      <Hsp_midline>E DI  L++ GQ     + + +EE YI+      +++V + + V  + +++G+RV +D     I   LP + DP V      E+ ++T+  +GG  EQI +LREV+E PL +PE F  +GI+PPKGVLL+GPPGTGKTL A+AVA    A FI    S +V KY+GE AR++RE+F  A+  + C+IF DE+DAIGG RF +G   D E+QRT++EL+ Q+DGFD  G  K++MATNRPDTLDPAL+RPGRLDRK+E  LP+  GR  IFKIH   +    +  FE   ++     GA+IR+  TEAG FAIR  R      D ++AV KV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YDL007W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:438047:439360:1 gene:YDL007W transcript:YDL007W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RPT2 description:ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; required for normal peptide hydrolysis by the core 20S particle; N-myristoylation of Rpt2p at Gly2 is involved in regulating the proper intracellular distribution of proteasome activity by controlling the nuclear localization of the 26S proteasome [Source:SGD;Acc:S000002165]</Hit_def>
  <Hit_accession>YDL007W</Hit_accession>
  <Hit_len>437</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>268.855</Hsp_bit-score>
      <Hsp_score>686</Hsp_score>
      <Hsp_evalue>1.23141e-85</Hsp_evalue>
      <Hsp_query-from>331</Hsp_query-from>
      <Hsp_query-to>1092</Hsp_query-to>
      <Hsp_hit-from>173</Hsp_hit-from>
      <Hsp_hit-to>426</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>132</Hsp_identity>
      <Hsp_positive>191</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>254</Hsp_align-len>
      <Hsp_qseq>VEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXXXXXNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFGLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKVATEKDFLEAVNKVIKS</Hsp_qseq>
      <Hsp_hseq>MDKSPTESYSDIGGLESQIQEIKESVELPLTHPELYEEMGIKPPKGVILYGAPGTGKTLLAKAVANQTSATFLRIVGSELIQKYLGDGPRLCRQIFKVAGENAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDDRGDVKVIMATNKIETLDPALIRPGRIDRKILFENPDLSTKKKILGIHTSKMNLSEDVNLETLVTTKDDLSGADIQAMCTEAGLLALRERRMQVTAEDFKQAKERVMKN</Hsp_hseq>
      <Hsp_midline>+++ P  +YSD+GG + QI++++E VE PL HPE +  +GI+PPKGV+L+G PGTGKTL A+AVAN+T A F+R++GSEL+QKY+G+G R+ R++F++A      ++F DEIDAIG  R+D  +GG+ E+QRTMLEL+NQLDGFD RG++KV+MATN+ +TLDPAL+RPGR+DRKI F  PDL  +  I  IH   M++  D+  E L     + +GA+I+++CTEAG+ A+R RR   T +DF +A  +V+K+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YOR117W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:545029:546333:1 gene:YOR117W transcript:YOR117W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RPT5 description:ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; recruited to the GAL1-10 promoter region upon induction of transcription; similar to human TBP1 [Source:SGD;Acc:S000005643]</Hit_def>
  <Hit_accession>YOR117W</Hit_accession>
  <Hit_len>434</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>263.462</Hsp_bit-score>
      <Hsp_score>672</Hsp_score>
      <Hsp_evalue>1.21179e-83</Hsp_evalue>
      <Hsp_query-from>229</Hsp_query-from>
      <Hsp_query-to>1083</Hsp_query-to>
      <Hsp_hit-from>138</Hsp_hit-from>
      <Hsp_hit-to>422</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>141</Hsp_identity>
      <Hsp_positive>194</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>290</Hsp_align-len>
      <Hsp_qseq>DQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDP-----TVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXXXXXNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFGLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKVATEKDFLEAVNKV</Hsp_qseq>
      <Hsp_hseq>DKLKPNDL-----VGVNKDSYLILDTLPSEFDSRVKAMEVDEKPTETYSDVGGLDKQIEELVEAIVLPMKRADKFKDMGIRAPKGALMYGPPGTGKTLLARACAAQTNATFLKLAAPQLVQMYIGEGAKLVRDAFALAKEKAPTIIFIDELDAIGTKRFDSEKSGDREVQRTMLELLNQLDGFSSDDRVKVLAATNRVDVLDPALLRSGRLDRKIEFPLPSEDSRAQILQIHSRKMTTDDDINWQELARSTDEFNGAQLKAVTVEAGMIALRNGQSSVKHEDFVEGISEV</Hsp_hseq>
      <Hsp_midline>D++ P D+     VGV+++ Y I   LP + D       V+EKP  TYSDVGG  +QIE+L E +  P+   ++F ++GI  PKG L++GPPGTGKTL ARA A +T+A F+++   +LVQ Y+GEGA++VR+ F +A+ K   +IF DE+DAIG  RFD    GD EVQRTMLEL+NQLDGF     +KVL ATNR D LDPAL+R GRLDRKIEF LP  + R  I +IH+R M+ + DI ++ LAR      GA++++V  EAGM A+R  +     +DF+E +++V</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YDR394W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1261681:1262967:1 gene:YDR394W transcript:YDR394W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RPT3 description:ATPase of the 19S regulatory particle of the 26S proteasome; one of ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; substrate of N-acetyltransferase B [Source:SGD;Acc:S000002802]</Hit_def>
  <Hit_accession>YDR394W</Hit_accession>
  <Hit_len>428</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>246.899</Hsp_bit-score>
      <Hsp_score>629</Hsp_score>
      <Hsp_evalue>2.78192e-77</Hsp_evalue>
      <Hsp_query-from>259</Hsp_query-from>
      <Hsp_query-to>1092</Hsp_query-to>
      <Hsp_hit-from>134</Hsp_hit-from>
      <Hsp_hit-to>417</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>138</Hsp_identity>
      <Hsp_positive>182</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>284</Hsp_align-len>
      <Hsp_qseq>GMRVGVDRNKYQIHIPLPPKIDPTVE-----EKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXXXXXNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEF-GLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKVATEKDFLEAVNKVIKS</Hsp_qseq>
      <Hsp_hseq>SMSVALHRHSNALVDILPPDSDSSISVMGENEKPDVTYADVGGLDMQKQEIREAVELPLVQADLYEQIGIDPPRGVLLYGPPGTGKTMLVKAVANSTKAAFIRVNGSEFVHKYLGEGPRMVRDVFRLARENAPSIIFIDEVDSIATKRFDAQTGSDREVQRILIELLTQMDGFDQSTNVKVIMATNRADTLDPALLRPGRLDRKIEFPSLRDRRERRLIFGTIASKMSLAPEADLDSLIIRNDSLSGAVIAAIMQEAGLRAVRKNRYVILQSDLEEAYATQVKT</Hsp_hseq>
      <Hsp_midline> M V + R+   +   LPP  D ++      EKPDVTY+DVGG   Q +++RE VE PL+  + +  +GI+PP+GVLL+GPPGTGKT+  +AVAN T A FIRV GSE V KY+GEG RMVR++F +AR     +IF DE+D+I   RFD   G D EVQR ++EL+ Q+DGFD   N+KV+MATNR DTLDPAL+RPGRLDRKIEF  L D   R  IF   A  MS+  +   + L     + +GA I ++  EAG+ A+R  R V  + D  EA    +K+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YDL126C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:236157:238664:-1 gene:YDL126C transcript:YDL126C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC48 description:AAA ATPase; subunit of polyUb-selective segregase complex involved in ERAD, INM-associated degradation (INMAD), mitotic spindle disassembly, macroautophagy, PMN, ribosome-associated degradation, ribophagy, homotypic ER membrane fusion, SCF complex disassembly, cell wall integrity during heat stress, and telomerase regulation; mobilizes membrane-anchored transcription factors by regulated Ub/proteasome-dependent processing (RUP); human ortholog VCP complements a cdc48 mutant [Source:SGD;Acc:S000002284]</Hit_def>
  <Hit_accession>YDL126C</Hit_accession>
  <Hit_len>835</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>203.756</Hsp_bit-score>
      <Hsp_score>517</Hsp_score>
      <Hsp_evalue>6.08588e-58</Hsp_evalue>
      <Hsp_query-from>346</Hsp_query-from>
      <Hsp_query-to>1035</Hsp_query-to>
      <Hsp_hit-from>210</Hsp_hit-from>
      <Hsp_hit-to>436</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>100</Hsp_identity>
      <Hsp_positive>147</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>231</Hsp_align-len>
      <Hsp_qseq>DVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXXXXXNEVQRTML-ELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFGLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRAR</Hsp_qseq>
      <Hsp_hseq>EVGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEI----DSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREK</Hsp_hseq>
      <Hsp_midline>+V Y D+GGC++Q+ ++RE+VE PL HP+ F  +GI+PP+GVL++GPPGTGKTL ARAVAN T A F  + G E++ K  GE    +R+ FE A      +IF DEI     +        + EV+R ++ +L+  +DG   R N+ V+ ATNRP+++DPAL R GR DR+++ G+PD  GR  + +IH ++M +  D+  E LA       GA+I S+C+EA M  IR +</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>187.578</Hsp_bit-score>
      <Hsp_score>475</Hsp_score>
      <Hsp_evalue>3.14423e-52</Hsp_evalue>
      <Hsp_query-from>214</Hsp_query-from>
      <Hsp_query-to>1059</Hsp_query-to>
      <Hsp_hit-from>439</Hsp_hit-from>
      <Hsp_hit-to>724</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>102</Hsp_identity>
      <Hsp_positive>160</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>286</Hsp_align-len>
      <Hsp_qseq>VVDLGDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXXXXXNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFGLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIR----ARRKVATEKD</Hsp_qseq>
      <Hsp_hseq>LIDLDEDEIDAEVLDSLGVTMDNFRFALGNSNPSALRETVVESVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIAKARGGSLGDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIEAHRQHEAEKE</Hsp_hseq>
      <Hsp_midline>++DL +     ++ + + V +D  ++ +    P  +  TV E  +VT+ DVGG  E  E+L+E VE P+LHP+++   G+ P KGVL +GPPGTGKTL A+AVA    A FI V G EL+  + GE    +R++F+ AR     ++F DE+D+I  AR            R + +L+ ++DG + + N+ V+ ATNRPD +DPA++RPGRLD+ I   LPD   R  I     R   +E  +    +A+     +GA++  +   A  +AI+    A R+   EK+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YGR270W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:1027370:1031509:1 gene:YGR270W transcript:YGR270W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YTA7 description:Protein that localizes to chromatin; has a role in regulation of histone gene expression; has a bromodomain-like region that interacts with the N-terminal tail of histone H3, and an ATPase domain; relocalizes to the cytosol in response to hypoxia; potentially phosphorylated by Cdc28p [Source:SGD;Acc:S000003502]</Hit_def>
  <Hit_accession>YGR270W</Hit_accession>
  <Hit_len>1379</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>187.963</Hsp_bit-score>
      <Hsp_score>476</Hsp_score>
      <Hsp_evalue>6.3542e-52</Hsp_evalue>
      <Hsp_query-from>346</Hsp_query-from>
      <Hsp_query-to>1113</Hsp_query-to>
      <Hsp_hit-from>409</Hsp_hit-from>
      <Hsp_hit-to>683</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>108</Hsp_identity>
      <Hsp_positive>156</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>278</Hsp_align-len>
      <Hsp_qseq>DVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDA-----CFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXXXXXNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFGLPDLEGRTHIFKIHARSMSVERDIRF-ELLARLCPNSTGAEIRSVCTEAGMFAI--------RARRKVATE--------KDFLEAVNKVIKSYAKFSAT</Hsp_qseq>
      <Hsp_hseq>NVNFDDIGGLDNYIDQLKEMVALPLLYPELYQNFNITPPRGVLFHGPPGTGKTLMARALAASCSSDERKITFFMRKGADILSKWVGEAERQLRLLFEEAKKHQPSIIFFDEIDGLAPVRSSKQEQIHASIVSTLLAL---MDGMDNRGQVIVIGATNRPDAVDPALRRPGRFDREFYFPLPDVKARFKILQIQTRKWSSPLSTNFIDKLAFLTKGYGGADLRSLCTEAALISIQRSFPQIYRSNDKLLVDPSKIKVKVSDFMLALKKIVPSSARSTGS</Hsp_hseq>
      <Hsp_midline>+V + D+GG    I++L+E+V  PLL+PE + N  I PP+GVL  GPPGTGKTL ARA+A    +      F    G++++ K+VGE  R +R LFE A+  +  +IFFDEID +   R          +  T+L L   +DG D RG + V+ ATNRPD +DPAL RPGR DR+  F LPD++ R  I +I  R  S      F + LA L     GA++RS+CTEA + +I        R+  K+  +         DF+ A+ K++ S A+ + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YLR397C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:912550:914892:-1 gene:YLR397C transcript:YLR397C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AFG2 description:ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex; is essential for pre-60S maturation and release of several preribosome maturation factors; releases Rlp24p from purified pre-60S particles in vitro; target of the ribosomal biosynthesis inhibitor diazaborine; may be involved in degradation of aberrant mRNAs [Source:SGD;Acc:S000004389]</Hit_def>
  <Hit_accession>YLR397C</Hit_accession>
  <Hit_len>780</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>181.03</Hsp_bit-score>
      <Hsp_score>458</Hsp_score>
      <Hsp_evalue>4.30667e-50</Hsp_evalue>
      <Hsp_query-from>250</Hsp_query-from>
      <Hsp_query-to>1131</Hsp_query-to>
      <Hsp_hit-from>469</Hsp_hit-from>
      <Hsp_hit-to>768</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>113</Hsp_identity>
      <Hsp_positive>161</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>306</Hsp_align-len>
      <Hsp_qseq>IEEGMRVGVDRNKYQIHIPL-----------PPKIDPTVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXXXXXNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFGLPDLEGRTHIFKIHARSMSVERD-IRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKVATEKDFLEAVNKVIKSYAKFSATPRYMTY</Hsp_qseq>
      <Hsp_hseq>IQRGLGTDANIDKFSLKVTLKDVESAMVDIRPSAMREIFLEMPKVYWSDIGGQEELKTKMKEMIQLPLEASETFARLGISAPKGVLLYGPPGCSKTLTAKALATESGINFLAVKGPEIFNKYVGESERAIREIFRKARSAAPSIIFFDEIDALSPDRDGSSTSAANHV---LTSLLNEIDGVEELKGVVIVAATNRPDEIDAALLRPGRLDRHIYVGPPDVNARLEILKKCTKKFNTEESGVDLHELADRTEGYSGAEVVLLCQEAGLAAIMEDLDVA--KVELRHFEKAFKGIAR-GITPEMLSY</Hsp_hseq>
      <Hsp_midline>I+ G+    + +K+ + + L           P  +     E P V +SD+GG +E   K++E+++ PL   E F  LGI  PKGVLL+GPPG  KTL A+A+A  +   F+ V G E+  KYVGE  R +RE+F  AR+    +IFFDEIDA+   R        N V   +  L+N++DG +    + ++ ATNRPD +D AL+RPGRLDR I  G PD+  R  I K   +  + E   +    LA      +GAE+  +C EAG+ AI     VA  K  L    K  K  A+   TP  ++Y</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>162.925</Hsp_bit-score>
      <Hsp_score>411</Hsp_score>
      <Hsp_evalue>1.16875e-43</Hsp_evalue>
      <Hsp_query-from>349</Hsp_query-from>
      <Hsp_query-to>1029</Hsp_query-to>
      <Hsp_hit-from>242</Hsp_hit-from>
      <Hsp_hit-to>470</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>84</Hsp_identity>
      <Hsp_positive>133</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>232</Hsp_align-len>
      <Hsp_qseq>VTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXXXXXNEVQ-RTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFGLPDLEGRTHIFKIHARSMSVERDI----RFELLARLCPNSTGAEIRSVCTEAGMFAIR</Hsp_qseq>
      <Hsp_hseq>LSYAAVGGLDKEIESLKSAIEIPLHQPTLFSSFGVSPPRGILLHGPPGTGKTMLLRVVANTSNAHVLTINGPSIVSKYLGETEAALRDIFNEARKYQPSIIFIDEI---DSIAPNRANDDSGEVESRVVATLLTLMDGMGAAGKVVVIAATNRPNSVDPALRRPGRFDQEVEIGIPDVDARFDILTKQFSRMSSDRHVLDSEAIKYIASKTHGYVGADLTALCRESVMKTIQ</Hsp_hseq>
      <Hsp_midline>++Y+ VGG  ++IE L+  +E PL  P  F + G+ PP+G+LL GPPGTGKT+  R VAN ++A  + + G  +V KY+GE    +R++F  AR  +  +IF DEI        +       EV+ R +  L+  +DG    G + V+ ATNRP+++DPAL RPGR D+++E G+PD++ R  I       MS +R +      + +A       GA++ ++C E+ M  I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YMR089C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:445609:448086:-1 gene:YMR089C transcript:YMR089C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YTA12 description:Mitochondrial inner membrane m-AAA protease component; mediates degradation of misfolded or unassembled proteins; also required for correct assembly of mitochondrial enzyme complexes; overexpression of human AFG3L2 complements respiratory defect of yeast afg3 yta12 double null mutation, but overexpression of disease-associated AFG3L2 variants does not; expression of both human SPG7 (paraplegin) and AFG3L2 complements yeast yta12 afg3 double mutation [Source:SGD;Acc:S000004695]</Hit_def>
  <Hit_accession>YMR089C</Hit_accession>
  <Hit_len>825</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>180.644</Hsp_bit-score>
      <Hsp_score>457</Hsp_score>
      <Hsp_evalue>8.4048e-50</Hsp_evalue>
      <Hsp_query-from>349</Hsp_query-from>
      <Hsp_query-to>1086</Hsp_query-to>
      <Hsp_hit-from>345</Hsp_hit-from>
      <Hsp_hit-to>592</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>107</Hsp_identity>
      <Hsp_positive>148</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>250</Hsp_align-len>
      <Hsp_qseq>VTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXXXXXN-EVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFGLPDLEGRTHIFKIHARSMSVERDIRFEL---LARLCPNSTGAEIRSVCTEAGMFAIRARRKVATEKDFLEAVNKVI</Hsp_qseq>
      <Hsp_hseq>IKFKDVAGCDEAKEEIMEFV-SFLKEPSRYEKMGAKIPRGAILSGPPGTGKTLLAKATAGEAGVPFYFVSGSEFVEMFVGVGAARVRDLFKTARENAPSIVFIDEIDAIGKARQKGNFSGANDERENTLNQMLVEMDGFTPADHVVVLAGTNRPDILDKALLRPGRFDRHINIDKPELEGRKAIFAVHLHHLKLAGEI-FDLKNRLAALTPGFSGADIANVCNEAALIAARSDEDAVKLNHFEQAIERVI</Hsp_hseq>
      <Hsp_midline>+ + DV GC E  E++ E V + L  P R+  +G + P+G +L GPPGTGKTL A+A A      F  V GSE V+ +VG GA  VR+LF+ AR     ++F DEIDAIG AR      G N E + T+ +++ ++DGF P  ++ VL  TNRPD LD AL+RPGR DR I    P+LEGR  IF +H   + +  +I F+L   LA L P  +GA+I +VC EA + A R+         F +A+ +VI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YLL034C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:70633:73146:-1 gene:YLL034C transcript:YLL034C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIX7 description:Putative ATPase of the AAA family; required for export of pre-ribosomal large subunits from the nucleus; distributed between the nucleolus, nucleoplasm, and nuclear periphery depending on growth conditions [Source:SGD;Acc:S000003957]</Hit_def>
  <Hit_accession>YLL034C</Hit_accession>
  <Hit_len>837</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>176.407</Hsp_bit-score>
      <Hsp_score>446</Hsp_score>
      <Hsp_evalue>2.99228e-48</Hsp_evalue>
      <Hsp_query-from>286</Hsp_query-from>
      <Hsp_query-to>1035</Hsp_query-to>
      <Hsp_hit-from>504</Hsp_hit-from>
      <Hsp_hit-to>759</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>101</Hsp_identity>
      <Hsp_positive>152</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>259</Hsp_align-len>
      <Hsp_qseq>KYQIHIPLPPKIDPTVEEK-----PDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXXXXXNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFGLPDLEGRTHIFKIHARSMS--VERDIRFELLAR--LCPNSTGAEIRSVCTEAGMFAIRAR</Hsp_qseq>
      <Hsp_hseq>KYEDFLKALPTIQPTAKREGFATVPDVTWANVGALQRVRLELNMAIVQPIKRPELYEKVGISAPGGVLLWGPPGCGKTLLAKAVANESRANFISIKGPELLNKYVGESERSIRQVFTRARASVPCVIFFDELDALVPRRDTSLSESSSRVVNTLL---TELDGLNDRRGIFVIGATNRPDMIDPAMLRPGRLDKSLFIELPNTEEKLDIIKTLTKSHGTPLSSDVDFEEIIRNEKCNNFSGADLAALVRESSVLALKRK</Hsp_hseq>
      <Hsp_midline>KY+  +   P I PT + +     PDVT+++VG  +    +L   +  P+  PE +  +GI  P GVLL+GPPG GKTL A+AVAN + A FI + G EL+ KYVGE  R +R++F  AR    C+IFFDE+DA+   R    +   + V  T+L    +LDG + R  I V+ ATNRPD +DPA++RPGRLD+ +   LP+ E +  I K   +S    +  D+ FE + R   C N +GA++ ++  E+ + A++ +</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>158.688</Hsp_bit-score>
      <Hsp_score>400</Hsp_score>
      <Hsp_evalue>4.10507e-42</Hsp_evalue>
      <Hsp_query-from>343</Hsp_query-from>
      <Hsp_query-to>1128</Hsp_query-to>
      <Hsp_hit-from>200</Hsp_hit-from>
      <Hsp_hit-to>447</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>92</Hsp_identity>
      <Hsp_positive>143</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>266</Hsp_align-len>
      <Hsp_qseq>PDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXXXXXNEVQRTMLELINQLDGFDPRGN----IKVLMATNRPDTLDPALMRPGRLDRKIEFGLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKVATEKDFLEAVNKVIKSYAKFSATPRYMT</Hsp_qseq>
      <Hsp_hseq>PNSSLKSLGGMDDVVAQLMELIGLPILHPEIFLSTGVEPPRGVLLHGPPGCGKTSIANALAGELQVPFISISAPSVVSGMSGESEKKIRDLFDEARSLAPCLVFFDEIDAITPKRDGGAQREME--RRIVAQLLTSMDELTMEKTNGKPVIIIGATNRPDSLDAALRRAGRFDREICLNVPNEVSRLHILKKMSDNLKIDGAIDFAKLAKLTPGFVGADLKALVTAAGTCAIK----------------RIFQTYANIKSTPTTAT</Hsp_hseq>
      <Hsp_midline>P+ +   +GG  + + +L E++  P+LHPE F++ G+EPP+GVLL GPPG GKT  A A+A      FI +    +V    GE  + +R+LF+ AR+   CL+FFDEIDAI   R           +R + +L+  +D           + ++ ATNRPD+LD AL R GR DR+I   +P+   R HI K  + ++ ++  I F  LA+L P   GA+++++ T AG  AI+                ++ ++YA   +TP   T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YER017C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:189503:191788:-1 gene:YER017C transcript:YER017C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AFG3 description:Mitochondrial inner membrane m-AAA protease component; mediates degradation of misfolded or unassembled proteins; also required for correct assembly of mitochondrial enzyme complexes; involved in cytoplasmic mRNA translation and aging; expression of human homolog AFG3L2 can complement yeast yta12 afg3 double mutant [Source:SGD;Acc:S000000819]</Hit_def>
  <Hit_accession>YER017C</Hit_accession>
  <Hit_len>761</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>172.94</Hsp_bit-score>
      <Hsp_score>437</Hsp_score>
      <Hsp_evalue>3.01906e-47</Hsp_evalue>
      <Hsp_query-from>349</Hsp_query-from>
      <Hsp_query-to>1101</Hsp_query-to>
      <Hsp_hit-from>285</Hsp_hit-from>
      <Hsp_hit-to>542</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>102</Hsp_identity>
      <Hsp_positive>150</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>259</Hsp_align-len>
      <Hsp_qseq>VTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXX--XXXXXXNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFGLPDLEGRTHIFKIHARSMSVERDIRFEL------LARLCPNSTGAEIRSVCTEAGMFAIRARRKVATEKDFLEAVNKVIKSYAK</Hsp_qseq>
      <Hsp_hseq>ISFKNVAGCDEAKQEIMEFVHF-LKNPGKYTKLGAKIPRGAILSGPPGTGKTLLAKATAGEANVPFLSVSGSEFVEMFVGVGASRVRDLFTQARSMAPSIIFIDEIDAIGKERGKGGALGGANDEREATLNQLLVEMDGFTTSDQVVVLAGTNRPDVLDNALMRPGRFDRHIQIDSPDVNGRQQIYLVHLKRLNLDPLLTDDMNNLSGKLATLTPGFTGADIANACNEAALIAARHNDPYITIHHFEQAIERVIAGLEK</Hsp_hseq>
      <Hsp_midline>+++ +V GC E  +++ E V   L +P ++  LG + P+G +L GPPGTGKTL A+A A   +  F+ V GSE V+ +VG GA  VR+LF  AR+    +IF DEIDAIG  R       G ++E + T+ +L+ ++DGF     + VL  TNRPD LD ALMRPGR DR I+   PD+ GR  I+ +H + ++++  +  ++      LA L P  TGA+I + C EA + A R      T   F +A+ +VI    K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YPR024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:610481:612724:1 gene:YPR024W transcript:YPR024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YME1 description:Catalytic subunit of i-AAA protease complex; complex is located in mitochondrial inner membrane; responsible for degradation of unfolded or misfolded mitochondrial gene products; serves as nonconventional translocation motor to pull PNPase into intermembrane space; also has role in intermembrane space protein folding; mutation causes elevated rate of mitochondrial turnover; human homolog YME1L1 can complement yeast null mutant [Source:SGD;Acc:S000006228]</Hit_def>
  <Hit_accession>YPR024W</Hit_accession>
  <Hit_len>747</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>161.384</Hsp_bit-score>
      <Hsp_score>407</Hsp_score>
      <Hsp_evalue>3.32466e-43</Hsp_evalue>
      <Hsp_query-from>340</Hsp_query-from>
      <Hsp_query-to>1086</Hsp_query-to>
      <Hsp_hit-from>275</Hsp_hit-from>
      <Hsp_hit-to>519</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>96</Hsp_identity>
      <Hsp_positive>145</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>249</Hsp_align-len>
      <Hsp_qseq>KPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXXXXXNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFGLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKVATEKDFLEAVNKVI</Hsp_qseq>
      <Hsp_hseq>KTNVKFDDVCGCDEARAELEEIVDF-LKDPTKYESLGGKLPKGVLLTGPPGTGKTLLARATAGEAGVDFFFMSGSEFDEVYVGVGAKRIRDLFAQARSRAPAIIFIDELDAIGGKRNPKDQAY---AKQTLNQLLVELDGFSQTSGIIIIGATNFPEALDKALTRPGRFDKVVNVDLPDVRGRADILKHHMKKITLADNVDPTIIARGTPGLSGAELANLVNQAAVYACQKNAVSVDMSHFEWAKDKIL</Hsp_hseq>
      <Hsp_midline>K +V + DV GC E   +L E+V+  L  P ++ +LG + PKGVLL GPPGTGKTL ARA A      F  + GSE  + YVG GA+ +R+LF  AR++   +IF DE+DAIGG R           ++T+ +L+ +LDGF     I ++ ATN P+ LD AL RPGR D+ +   LPD+ GR  I K H + +++  ++   ++AR  P  +GAE+ ++  +A ++A +          F  A +K++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YNL329C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:19541:22633:-1 gene:YNL329C transcript:YNL329C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PEX6 description:AAA-peroxin; heterodimerizes with AAA-peroxin Pex1p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol; mutations in human PEX6 can lead to severe peroxisomal disorders and early death [Source:SGD;Acc:S000005273]</Hit_def>
  <Hit_accession>YNL329C</Hit_accession>
  <Hit_len>1030</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>160.614</Hsp_bit-score>
      <Hsp_score>405</Hsp_score>
      <Hsp_evalue>1.23488e-42</Hsp_evalue>
      <Hsp_query-from>280</Hsp_query-from>
      <Hsp_query-to>1026</Hsp_query-to>
      <Hsp_hit-from>714</Hsp_hit-from>
      <Hsp_hit-to>955</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>91</Hsp_identity>
      <Hsp_positive>145</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>252</Hsp_align-len>
      <Hsp_qseq>RNKYQIHIPLPPKIDPTVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXXXXXNEVQRTMLELINQLDGFDPRGN-IKVLMATNRPDTLDPALMRPGRLDRKIEFGLPDLEGRT-HIFKIHARSMSVERDIRFELLARLCP-NSTGAEIRSVCTEAGMFAI</Hsp_qseq>
      <Hsp_hseq>RNEFSVSIGAP--------QIPNVTWDDIGGIDFVKGEILDTIDMPLKHPELFTS-GMKKRSGILFYGPPGTGKTLMAKAIATNFSLNFFSVKGPELLNMYIGESEANVRRVFQKAREAKPCVIFFDEI-DSVAPKRGNQGDSGGVMDRIVSQLLAELDGMSTDADGVFVIGATNRPDLLDEALLRPGRFDKLLYLGIPDTDTKQLNILEALTRKFVLDNDVKLIELAKLCPFNYTGADFYALCSDAMLNAM</Hsp_hseq>
      <Hsp_midline>RN++ + I  P        + P+VT+ D+GG      ++ + ++ PL HPE F + G++   G+L +GPPGTGKTL A+A+A      F  V G EL+  Y+GE    VR +F+ AR  K C+IFFDEI      +  +       + R + +L+ +LDG     + + V+ ATNRPD LD AL+RPGR D+ +  G+PD + +  +I +   R   ++ D++   LA+LCP N TGA+  ++C++A + A+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YPR173C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:886524:887837:-1 gene:YPR173C transcript:YPR173C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VPS4 description:AAA-ATPase involved in multivesicular body (MVB) protein sorting; ATP-bound Vps4p localizes to endosomes and catalyzes ESCRT-III disassembly and membrane release; ATPase activity is activated by Vta1p; regulates cellular sterol metabolism [Source:SGD;Acc:S000006377]</Hit_def>
  <Hit_accession>YPR173C</Hit_accession>
  <Hit_len>437</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>133.265</Hsp_bit-score>
      <Hsp_score>334</Hsp_score>
      <Hsp_evalue>9.18118e-35</Hsp_evalue>
      <Hsp_query-from>253</Hsp_query-from>
      <Hsp_query-to>1059</Hsp_query-to>
      <Hsp_hit-from>102</Hsp_hit-from>
      <Hsp_hit-to>362</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>97</Hsp_identity>
      <Hsp_positive>146</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>270</Hsp_align-len>
      <Hsp_qseq>EEGMRVGVDRNKYQIHIPLPPKIDPTVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXXXXXNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFGLPDLEGRTHIFKIH-ARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKVATEKD</Hsp_qseq>
      <Hsp_hseq>EEGEDNGGEDNK-KLRGALSSAI---LSEKPNVKWEDVAGLEGAKEALKEAVILPVKFPHLFKG-NRKPTSGILLYGPPGTGKSYLAKAVATEANSTFFSVSSSDLVSKWMGESEKLVKQLFAMARENKPSIIFIDEVDALTGTRGEGESEASRRIKTELLVQMNGV-GNDSQG-VLVLGATNIPWQLDSAIRR--RFERRIYIPLPDLAARTTMFEINVGDTPCVLTKEDYRTLGAMTEGYSGSDIAVVVKDALMQPIRKIQSATHFKD</Hsp_hseq>
      <Hsp_midline>EEG   G + NK ++   L   I   + EKP+V + DV G +   E L+E V  P+  P  F     +P  G+LL+GPPGTGK+  A+AVA   ++ F  V  S+LV K++GE  ++V++LF MAR  K  +IF DE+DA+ G R +  +     ++  +L  +N + G D +G + VL ATN P  LD A+ R  R +R+I   LPDL  RT +F+I+   +  V     +  L  +    +G++I  V  +A M  IR  +     KD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YPL074W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:415763:418027:1 gene:YPL074W transcript:YPL074W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YTA6 description:Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family; localized to the cortex of mother cells but not to daughter cells; relocalizes from cytoplasm to plasma membrane foci upon DNA replication stress [Source:SGD;Acc:S000005995]</Hit_def>
  <Hit_accession>YPL074W</Hit_accession>
  <Hit_len>754</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>133.265</Hsp_bit-score>
      <Hsp_score>334</Hsp_score>
      <Hsp_evalue>1.09686e-33</Hsp_evalue>
      <Hsp_query-from>349</Hsp_query-from>
      <Hsp_query-to>1029</Hsp_query-to>
      <Hsp_hit-from>468</Hsp_hit-from>
      <Hsp_hit-to>701</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>85</Hsp_identity>
      <Hsp_positive>129</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>237</Hsp_align-len>
      <Hsp_qseq>VTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXXXXXNEVQRTMLELINQLDG----FDPRGN-----IKVLMATNRPDTLDPALMRPGRLDRKIEFGLPDLEGRT-HIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIR</Hsp_qseq>
      <Hsp_hseq>VYWEDIAGLRNAKNSLKEAVVYPFLRPDLFKGLR-EPVRGMLLFGPPGTGKTMIAKAVATESNSTFFSVSASSLLSKYLGESEKLVRALFYMAKKLSPSIIFIDEIDSMLTARSDNENESSRRIKTELLIQWSSLSSATAQSEDRNNTLDSRVLVLGATNLPWAIDDAARR--RFSRKLYIPLPDYETRLYHLKRLMAKQKNSLQDLDYELITEMTEGFSGSDLTSLAKEAAMEPIR</Hsp_hseq>
      <Hsp_midline>V + D+ G +     L+E V  P L P+ F  L  EP +G+LLFGPPGTGKT+ A+AVA  +++ F  V  S L+ KY+GE  ++VR LF MA+     +IF DEID++  AR D+       ++  +L   + L       + R N     + VL ATN P  +D A  R  R  RK+   LPD E R  H+ ++ A+  +  +D+ +EL+  +    +G+++ S+  EA M  IR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YKL197C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:70734:73865:-1 gene:YKL197C transcript:YKL197C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PEX1 description:AAA-peroxin; heterodimerizes with AAA-peroxin Pex6p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol; induced by oleic acid and upregulated during anaerobiosis; mutations in human PEX1 can lead to severe peroxisomal disorders and early death [Source:SGD;Acc:S000001680]</Hit_def>
  <Hit_accession>YKL197C</Hit_accession>
  <Hit_len>1043</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>130.954</Hsp_bit-score>
      <Hsp_score>328</Hsp_score>
      <Hsp_evalue>7.59073e-33</Hsp_evalue>
      <Hsp_query-from>331</Hsp_query-from>
      <Hsp_query-to>1059</Hsp_query-to>
      <Hsp_hit-from>688</Hsp_hit-from>
      <Hsp_hit-to>936</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>79</Hsp_identity>
      <Hsp_positive>135</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>252</Hsp_align-len>
      <Hsp_qseq>VEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXXXXXNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFGLPDLEGRTHIFKIHARS---------MSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKVATEKD</Hsp_qseq>
      <Hsp_hseq>LTKETNIKWGDIGALANAKDVLLETLEWPTKYEPIFVNCPLRLRSGILLYGYPGCGKTLLASAVAQQCGLNFISVKGPEILNKFIGASEQNIRELFERAQSVKPCILFFDEFDSIAPKRGHDSTGVTD---RVVNQLLTQMDGAEGLDGVYILAATSRPDLIDSALLRPGRLDKSVICNIPTESERLDILQAIVNSKDKDTGQKKFALEKNADLKLIAEKTAGFSGADLQGLCYNAYLKSVHRWLSAADQSE</Hsp_hseq>
      <Hsp_midline>+ ++ ++ + D+G      + L E +E P  +   FVN  +    G+LL+G PG GKTL A AVA +    FI V G E++ K++G   + +RELFE A++ K C++FFDE D+I   R  D  G  +   R + +L+ Q+DG +    + +L AT+RPD +D AL+RPGRLD+ +   +P    R  I +    S          ++E++   +L+A      +GA+++ +C  A + ++      A + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YBR080C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:398614:400890:-1 gene:YBR080C transcript:YBR080C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SEC18 description:AAA ATPase and SNARE disassembly chaperone; required for vesicular transport between ER and Golgi, the &apos;priming&apos; step in homotypic vacuole fusion, autophagy, and protein secretion; releases Sec17p from SNAP complexes; has similarity to mammalian N-ethylmaleimide-sensitive factor (NSF) [Source:SGD;Acc:S000000284]</Hit_def>
  <Hit_accession>YBR080C</Hit_accession>
  <Hit_len>758</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>130.183</Hsp_bit-score>
      <Hsp_score>326</Hsp_score>
      <Hsp_evalue>1.32982e-32</Hsp_evalue>
      <Hsp_query-from>340</Hsp_query-from>
      <Hsp_query-to>1098</Hsp_query-to>
      <Hsp_hit-from>231</Hsp_hit-from>
      <Hsp_hit-to>514</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>99</Hsp_identity>
      <Hsp_positive>143</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>289</Hsp_align-len>
      <Hsp_qseq>KPDVTYSD--VGGCKEQIEKL-REVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVI-GSELVQKYVGEGARMVRELFEMARTKKAC--------LIFFDEIXXXXXXXXXX---XXXXXNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFGLPDLEGRTHIFKIHARSMS----VERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIR-----------------ARRKVATEKDFLEAVNKVIKSYA</Hsp_qseq>
      <Hsp_hseq>RPDFKFEDLGVGGLDKEFTKIFRRAFASRIFPPSVIEKLGISHVKGLLLYGPPGTGKTLIARKIGTMLNAKEPKIVNGPEILSKYVGSSEENIRNLFKDAEAEYRAKGEESSLHIIIFDELDSVFKQRGSRGDGTGVGDNVVN----QLLAKMDGVDQLNNILVIGMTNRKDLIDSALLRPGRFEVQVEIHLPDEKGRLQIFDIQTKKMRENNMMSDDVNLAELAALTKNFSGAEIEGLVKSASSFAINKTVNIGKGATKLNTKDIAKLKV-TREDFLNALNDVTPAFG</Hsp_hseq>
      <Hsp_midline>+PD  + D  VGG  ++  K+ R    + +  P     LGI   KG+LL+GPPGTGKTL AR +    +A   +++ G E++ KYVG     +R LF+ A  +           +I FDE+D++   R         GDN V     +L+ ++DG D   NI V+  TNR D +D AL+RPGR + ++E  LPD +GR  IF I  + M     +  D+    LA L  N +GAEI  +   A  FAI                  A+ KV T +DFL A+N V  ++ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YGR028W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:542203:543291:1 gene:YGR028W transcript:YGR028W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MSP1 description:Highly-conserved N-terminally anchored AAA-ATPase; distributed in the mitochondrial outer membrane and peroxisomes; involved in mitochondrial protein sorting; functions as an extraction engine in local organelle surveillance to remove and initiate degradation of mistargeted proteins, ensuring fidelity of organelle-specific localization of tail-anchored proteins; contains an N-terminal transmembrane domain and C-terminal cytoplasmic ATPase domain [Source:SGD;Acc:S000003260]</Hit_def>
  <Hit_accession>YGR028W</Hit_accession>
  <Hit_len>362</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>122.479</Hsp_bit-score>
      <Hsp_score>306</Hsp_score>
      <Hsp_evalue>1.83289e-31</Hsp_evalue>
      <Hsp_query-from>346</Hsp_query-from>
      <Hsp_query-to>1044</Hsp_query-to>
      <Hsp_hit-from>87</Hsp_hit-from>
      <Hsp_hit-to>320</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>130</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>240</Hsp_align-len>
      <Hsp_qseq>DVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGI-EPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXXXXXNEVQRTM-LELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFGLPDLEGRTHIFKIHARSMSVERD-IRFELLARLCPNSTGAEIRSVCTEAGMFA----IRARRKV</Hsp_qseq>
      <Hsp_hseq>NITFQDIGGLDPLISDLHESVIYPLMMPEVYSNSPLLQAPSGVLLYGPPGCGKTMLAKALAKESGANFISIRMSSIMDKWYGESNKIVDAMFSLANKLQPCIIFIDEI----DSFLRERSSTDHEVTATLKAEFMTLWDGLLNNGRVMIIGATNRINDIDDAFLR--RLPKRFLVSLPGSDQRYKILSVLLKDTKLDEDEFDLQLIADNTKGFSGSDLKELCREAALDAAKEYIKQKRQL</Hsp_hseq>
      <Hsp_midline>++T+ D+GG    I  L E V  PL+ PE + N  + + P GVLL+GPPG GKT+ A+A+A  + A FI +  S ++ K+ GE  ++V  +F +A   + C+IF DEI     +   + +  D+EV  T+  E +   DG    G + ++ ATNR + +D A +R  RL ++    LP  + R  I  +  +   ++ D    +L+A      +G++++ +C EA + A    I+ +R++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YER047C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:243810:246503:-1 gene:YER047C transcript:YER047C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAP1 description:Putative ATPase of the AAA family; interacts with the Sin1p transcriptional repressor in the two-hybrid system [Source:SGD;Acc:S000000849]</Hit_def>
  <Hit_accession>YER047C</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>109.383</Hsp_bit-score>
      <Hsp_score>272</Hsp_score>
      <Hsp_evalue>8.92496e-26</Hsp_evalue>
      <Hsp_query-from>346</Hsp_query-from>
      <Hsp_query-to>1029</Hsp_query-to>
      <Hsp_hit-from>601</Hsp_hit-from>
      <Hsp_hit-to>844</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>81</Hsp_identity>
      <Hsp_positive>120</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>252</Hsp_align-len>
      <Hsp_qseq>DVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXXXXXNEVQRTML-ELINQL---------------DGFDPRGN-----IKVLMATNRPDTLDPALMRPGRLDRKIEFGLPDLEGRTHIFK---IHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIR</Hsp_qseq>
      <Hsp_hseq>EVHWDDIAGLESAKYSLKEAVVYPFLRPDLFRGLR-EPVRGMLLFGPPGTGKTMLARAVATESHSTFFSISASSLTSKYLGESEKLVRALFAIAKKLSPSIIFVDEI---DSIMGSRNNENENESSRRIKNEFLVQWSSLSSAAAGSNKSNTNNSDTNGDEDDTRVLVLAATNLPWSIDEAARR--RFVRRQYIPLPEDQTRHVQFKKLLSHQKHTLTESD--FDELVKITEGYSGSDITSLAKDAAMGPLR</Hsp_hseq>
      <Hsp_midline>+V + D+ G +     L+E V  P L P+ F  L  EP +G+LLFGPPGTGKT+ ARAVA  + + F  +  S L  KY+GE  ++VR LF +A+     +IF DEI              +NE  R +  E + Q                +  D  G+     + VL ATN P ++D A  R  R  R+    LP+ + R   FK    H +    E D  F+ L ++    +G++I S+  +A M  +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>912879466</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

