<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0063483-RA transcript Note:&quot;Similar to CPOX Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial (Homo sapiens)&quot; offset:600 AED:0.36 eAED:0.72 QI:600|0|0|1|0|0|3|0|121</BlastOutput_query-def>
  <BlastOutput_query-len>966</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0063483-RA transcript Note:&quot;Similar to CPOX Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial (Homo sapiens)&quot; offset:600 AED:0.36 eAED:0.72 QI:600|0|0|1|0|0|3|0|121</Iteration_query-def>
  <Iteration_query-len>966</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDR044W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:546642:547628:1 gene:YDR044W transcript:YDR044W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HEM13 description:Coproporphyrinogen III oxidase; oxygen-requiring enzyme that catalyzes sixth step in heme biosynthetic pathway; transcription is repressed by oxygen and heme (via Rox1p and Hap1p); human homolog CPOX can complement yeast mutant and allow growth of haploid null after sporulation of a heterozygous diploid [Source:SGD;Acc:S000002451]</Hit_def>
  <Hit_accession>YDR044W</Hit_accession>
  <Hit_len>328</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>96.2857</Hsp_bit-score>
      <Hsp_score>238</Hsp_score>
      <Hsp_evalue>2.47262e-23</Hsp_evalue>
      <Hsp_query-from>592</Hsp_query-from>
      <Hsp_query-to>951</Hsp_query-to>
      <Hsp_hit-from>111</Hsp_hit-from>
      <Hsp_hit-to>296</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>68</Hsp_gaps>
      <Hsp_align-len>187</Hsp_align-len>
      <Hsp_qseq>FVAMGVSSVIHPHSPHVPTLHFNYRYFEIQQQQG-----------------------------------------------GCDDYFSLPHRGGERRGVGGIFFDDLTSPSAAHHPLTSATPSAAHHP-----LTSPSAMPY---------------VEFNLLHDRGTKFGLATPGSRTESILMSLP</Hsp_qseq>
      <Hsp_hseq>FFACGLSMVIHPVNPHAPTTHLNYRYFETWNQDGTPQTWWFGGGADLTPSYLYEEDGQLFHQLHKDALDKHDTALYPRFKKWCDEYFYITHRK-ETRGIGGIFFDDYDERDPQEILKMVEDCFDAFLPSYLTIVKRRKDMPYTKEEQQWQAIRRGRYVEFNLIYDRGTQFGLRTPGSRVESILMSLP</Hsp_hseq>
      <Hsp_midline>F A G+S VIHP +PH PT H NYRYFE   Q G                                                CD+YF + HR  E RG+GGIFFDD                  A  P     +     MPY               VEFNL++DRGT+FGL TPGSR ESILMSLP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>538255544</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0043080-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.26 eAED:0.26 QI:0|0.5|0|1|0|0|3|622|193</Iteration_query-def>
  <Iteration_query-len>1204</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>92</Statistics_hsp-len>
      <Statistics_eff-space>712821903</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056146-RA transcript Note:&quot;Similar to NEK5 Serine/threonine-protein kinase Nek5 (Homo sapiens)&quot; offset:1229 AED:0.02 eAED:0.02 QI:1229|0.93|1|1|0.33|0.37|16|919|403</Iteration_query-def>
  <Iteration_query-len>3360</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YAR018C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:170396:171703:-1 gene:YAR018C transcript:YAR018C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN3 description:Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol [Source:SGD;Acc:S000000071]</Hit_def>
  <Hit_accession>YAR018C</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>109.768</Hsp_bit-score>
      <Hsp_score>273</Hsp_score>
      <Hsp_evalue>8.82994e-26</Hsp_evalue>
      <Hsp_query-from>80</Hsp_query-from>
      <Hsp_query-to>673</Hsp_query-to>
      <Hsp_hit-from>170</Hsp_hit-from>
      <Hsp_hit-to>409</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>121</Hsp_positive>
      <Hsp_gaps>52</Hsp_gaps>
      <Hsp_align-len>245</Hsp_align-len>
      <Hsp_qseq>VLHRDIKAQNIFLTNNNSS--------------------------------------IKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYKPLSSRYSYDIRSVLAQMLKTNPRNRPSINTILCKCFL-----SSRIQKFLGPEL-YNEEFSH-TVIHSKKAVSGQR--SKLAQQGKAPRANPSVAQVHRKVVADRAVS</Hsp_qseq>
      <Hsp_hseq>VIHRDLKPGNIFLSYDDSDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLAKSLETSIQFATTYVGTPYYMSPEVLMDQPYSPLSDIWSLGCVIFEMCSLHPPFQAKNYLELQTKIKNGKCDTVPEYYSRGLNAIIHSMIDVNLRTRPSTFELLQDIQIRTARKSLQLERFERKLLDYENELTNIEKILEKQAIEYERELSQLKEQ-----FTQAVEERAREVISGKKVG</Hsp_hseq>
      <Hsp_midline>V+HRD+K  NIFL+ ++S                                       +KLGDFG+A+ L  +++ A T +GTPYY+SPE+  + PY+  SDIWSLGCV++E+C+L+ PF+  +   L  KI  G    +   YS  + +++  M+  N R RPS   +L    +     S ++++F    L Y  E ++   I  K+A+  +R  S+L +Q        +V +  R+V++ + V </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>103.605</Hsp_bit-score>
      <Hsp_score>257</Hsp_score>
      <Hsp_evalue>6.98022e-23</Hsp_evalue>
      <Hsp_query-from>8</Hsp_query-from>
      <Hsp_query-to>487</Hsp_query-to>
      <Hsp_hit-from>124</Hsp_hit-from>
      <Hsp_hit-to>285</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>164</Hsp_align-len>
      <Hsp_qseq>FPHAQVLNWFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNN-KSDIWSLGCVLYELCTLNHPF--EGNSLRHLVMKICQGSYK-PLSSRYSYDIRSVLAQMLKTNPRNRPSINTILCKCFL</Hsp_qseq>
      <Hsp_hseq>LPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLL-DSFYNIKIADFGMAALQTDA-DLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLL</Hsp_hseq>
      <Hsp_midline> P  + +N F QI + + + H   ++HRD+K +N+ L ++  +IK+ DFG+A + T+  +L  T  G+P+Y +PEI    PY    SD+WS G +L+ L T   PF  E  ++R L++K+ +G ++ P  +  S D + ++ ++L  +PR R  I  IL    L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>103.99</Hsp_bit-score>
      <Hsp_score>258</Hsp_score>
      <Hsp_evalue>7.24202e-23</Hsp_evalue>
      <Hsp_query-from>8</Hsp_query-from>
      <Hsp_query-to>472</Hsp_query-to>
      <Hsp_hit-from>211</Hsp_hit-from>
      <Hsp_hit-to>364</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>157</Hsp_align-len>
      <Hsp_qseq>FPHAQVLNWFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARI-LTNTMELARTCIGTPYYLSPEICENCPYNNK-SDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYKPLSSRYSYDIRSVLAQMLKTNPRNRPSINTIL</Hsp_qseq>
      <Hsp_hseq>LPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPN--KLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQ-MPSNLSSEARDLISKILVIDPEKRITTQEIL</Hsp_hseq>
      <Hsp_midline> P  + +++F QI   V + H   + HRD+K +N+ L   N  IK+ DFG+A + L N  +L +T  G+P+Y SPEI    PY+   SD+WS G VL+ L T + PF  ++++ L++K+  G Y+ + S  S + R +++++L  +P  R +   IL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>101.679</Hsp_bit-score>
      <Hsp_score>252</Hsp_score>
      <Hsp_evalue>2.00514e-22</Hsp_evalue>
      <Hsp_query-from>20</Hsp_query-from>
      <Hsp_query-to>472</Hsp_query-to>
      <Hsp_hit-from>180</Hsp_hit-from>
      <Hsp_hit-to>332</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>154</Hsp_align-len>
      <Hsp_qseq>QVLNWFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEIC--ENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKI-CQGSYKPLSSRYSYDIRSVLAQMLKTNPRNRPSINTIL</Hsp_qseq>
      <Hsp_hseq>EVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFF-DSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRDKPISDEGKILIRDILSLDPIERPSLTEIM</Hsp_hseq>
      <Hsp_midline>+V  +  QIC A+K++H R+V+HRD+K  NIF  ++N ++K+GDFG+A +L N  E   T  GTP Y++PE+   ++  ++ + DIWSLG +LY L     PF+   +  +  +I C+    P     S + + ++  +L  +P  RPS+  I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>98.5969</Hsp_bit-score>
      <Hsp_score>244</Hsp_score>
      <Hsp_evalue>2.75626e-21</Hsp_evalue>
      <Hsp_query-from>41</Hsp_query-from>
      <Hsp_query-to>628</Hsp_query-to>
      <Hsp_hit-from>127</Hsp_hit-from>
      <Hsp_hit-to>317</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>198</Hsp_align-len>
      <Hsp_qseq>QICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPE-ICENCPYNNKSDIWSLGCVLYELCTLNHPF-EGNSLRHLVMKICQGSYKPLSSRYSYDIRSVLAQMLKTNPRNRPSINTILCKCFLSSRIQKFLGPELYNEEFSHTVIHSKKAVSGQRSKLAQQGKAPRANPS</Hsp_qseq>
      <Hsp_hseq>ELLVALKCIHKDNVIHRDIKAANVLITNE-GNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIKSKPPRLEDRSYSTSLKEFIALCLDEDPKERLSADDLLKSKFI--RAHKATPTSILKELISRYLLFRDK----NKNKYKIEGSIPENEPS</Hsp_hseq>
      <Hsp_midline>++ +A+K IH   V+HRDIKA N+ +TN   ++KL DFG+A  +  T    +T  GTPY+++PE I E   Y+ K DIWSLG   YE+ T N P+ +  +LR + + I     +     YS  ++  +A  L  +P+ R S + +L   F+  R  K     +  E  S  ++   K     ++K   +G  P   PS</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.5893</Hsp_bit-score>
      <Hsp_score>231</Hsp_score>
      <Hsp_evalue>3.04562e-20</Hsp_evalue>
      <Hsp_query-from>8</Hsp_query-from>
      <Hsp_query-to>487</Hsp_query-to>
      <Hsp_hit-from>113</Hsp_hit-from>
      <Hsp_hit-to>272</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>162</Hsp_align-len>
      <Hsp_qseq>FPHAQVLNWFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEI--CENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYKPLSSRYSYDIRSVLAQMLKTNPRNRPSINTILCKCFL</Hsp_qseq>
      <Hsp_hseq>LPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILL-NEEGMVKLGDFGVSGHIRSTLK-RDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPPLSKYDPMKVMTNLPKRKPPKLQGPFSDAAKDFVAGCLVKTPADRPSAYNLLSFEFV</Hsp_hseq>
      <Hsp_midline> P  +V     ++ L +K++H+++ +HRDIKA NI L N    +KLGDFG++  + +T++   T +GTPY+++PE+  CE   YN K+DIWSLG   YEL     P        ++  + +     L   +S   +  +A  L   P +RPS   +L   F+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>92.4337</Hsp_bit-score>
      <Hsp_score>228</Hsp_score>
      <Hsp_evalue>1.81271e-19</Hsp_evalue>
      <Hsp_query-from>35</Hsp_query-from>
      <Hsp_query-to>487</Hsp_query-to>
      <Hsp_hit-from>138</Hsp_hit-from>
      <Hsp_hit-to>287</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>152</Hsp_align-len>
      <Hsp_qseq>FVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNN-KSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYKPLSSRYSYDIRSVLAQMLKTNPRNRPSINTILCKCFL</Hsp_qseq>
      <Hsp_hseq>FAQISGAVYYAHSMHCVHRDLKLENILL-DKNGNAKLTDFGFTRECMTKTTLETVC-GTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDAKVIPDDARDLISRLLAKNPGERPSLSQVLRHPFL</Hsp_hseq>
      <Hsp_midline>F QI  AV + H    +HRD+K +NI L + N + KL DFG  R       L   C GT  Y++PE+ E   Y+  K DIWSLG +LY L T   PF+ +       KI     K  +     D R +++++L  NP  RPS++ +L   FL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>89.7373</Hsp_bit-score>
      <Hsp_score>221</Hsp_score>
      <Hsp_evalue>3.52198e-19</Hsp_evalue>
      <Hsp_query-from>8</Hsp_query-from>
      <Hsp_query-to>496</Hsp_query-to>
      <Hsp_hit-from>143</Hsp_hit-from>
      <Hsp_hit-to>312</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>171</Hsp_align-len>
      <Hsp_qseq>FPHAQVLNWFVQICLAVKHIHDRKVLHRDIKAQNIFLTN--NNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYKPLS------SRYSYDIRSVLAQMLKTNPRNRPSINTILCKCFLSSR</Hsp_qseq>
      <Hsp_hseq>FTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSPFIAESVEGF-MEECTASRYPVTFHMPYWDNISIDVKRFILKALRLNPADRPTATELLDDPWITSK</Hsp_hseq>
      <Hsp_midline>F     +   VQI  AV+++H + V+HRD+K +N+   +   NS + + DFGIA+ L    +L     G+  Y++PE+     +    DIWS+G + Y L     PF   S+    M+ C  S  P++         S D++  + + L+ NP +RP+   +L   +++S+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>91.6633</Hsp_bit-score>
      <Hsp_score>226</Hsp_score>
      <Hsp_evalue>3.76248e-19</Hsp_evalue>
      <Hsp_query-from>8</Hsp_query-from>
      <Hsp_query-to>472</Hsp_query-to>
      <Hsp_hit-from>128</Hsp_hit-from>
      <Hsp_hit-to>284</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>159</Hsp_align-len>
      <Hsp_qseq>FPHAQVLNWFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNN-KSDIWSLGCVLYELCTLNHPF--EGNSLRHLVMKICQGSYK-PLSSRYSYDIRSVLAQMLKTNPRNRPSINTIL</Hsp_qseq>
      <Hsp_hseq>LPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLL-DHKYNIKIADFGMAALETEGKLLETSC-GSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERRIKTRDIL</Hsp_hseq>
      <Hsp_midline> P  + + +F QI + V + H   ++HRD+K +N+ L ++  +IK+ DFG+A + T    L  +C G+P+Y +PEI    PY    SD+WS G +L+ L T   PF  E  ++R L++K+ +G ++ P     S + + ++ ++L  +P  R     IL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>89.7373</Hsp_bit-score>
      <Hsp_score>221</Hsp_score>
      <Hsp_evalue>5.62434e-19</Hsp_evalue>
      <Hsp_query-from>44</Hsp_query-from>
      <Hsp_query-to>526</Hsp_query-to>
      <Hsp_hit-from>326</Hsp_hit-from>
      <Hsp_hit-to>494</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>ICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKIC----------QGSYKP-LSSRYSYDIRSVLAQMLKTNPRNRPSINTILCKCFLSSRIQKFLGPELY</Hsp_qseq>
      <Hsp_hseq>VLRGLSYLHERKVIHRDIKPQNILL-NEKGEIKLCDFGVSGEAVNS--LAMTFTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRFPFESDKITQNVAPIELLTMILTFSPQLKDEPELDISWSKTFRSFIDYCLKKDARERPSPRQMLKHPWIVGQMKKKVNMERF</Hsp_hseq>
      <Hsp_midline>+   + ++H+RKV+HRDIK QNI L N    IKL DFG++    N+  LA T  GT +Y++PE  +  PY+   D+WSLG  L E+     PFE + +   V  I           Q   +P L   +S   RS +   LK + R RPS   +L   ++  +++K +  E +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>89.3521</Hsp_bit-score>
      <Hsp_score>220</Hsp_score>
      <Hsp_evalue>1.10209e-18</Hsp_evalue>
      <Hsp_query-from>41</Hsp_query-from>
      <Hsp_query-to>490</Hsp_query-to>
      <Hsp_hit-from>490</Hsp_hit-from>
      <Hsp_hit-to>640</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>154</Hsp_align-len>
      <Hsp_qseq>QICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPF-EGNSLRHLVMKICQGSYK---PLSSRYSYDIRSVLAQMLKTNPRNRPSINTILCKCFLS</Hsp_qseq>
      <Hsp_hseq>ETCQGLKFLHNKKIIHRDIKSDNILL-NSQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANNGSPKLRHPES--VSKQTKQFLDACLQVNVESRASVRKLLTFEFLS</Hsp_hseq>
      <Hsp_midline>+ C  +K +H++K++HRDIK+ NI L N+   +K+ DFG    LT       T +GTPY+++PEI     Y+ K D+WSLG +L E+     P+   + L+ L +    GS K   P S   S   +  L   L+ N  +R S+  +L   FLS</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.5817</Hsp_bit-score>
      <Hsp_score>218</Hsp_score>
      <Hsp_evalue>2.95798e-18</Hsp_evalue>
      <Hsp_query-from>32</Hsp_query-from>
      <Hsp_query-to>493</Hsp_query-to>
      <Hsp_hit-from>126</Hsp_hit-from>
      <Hsp_hit-to>274</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>154</Hsp_align-len>
      <Hsp_qseq>WFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYKPLSSRYSYDIRSVLAQMLKTNPRNRPSINTILCKCFLSS</Hsp_qseq>
      <Hsp_hseq>YVTQTLLGLKYLHGEGVIHRDIKAANILLSADNT-VKLADFGVSTIVNSS---ALTLAGTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNPPYHNLTDANIYYAVENDTYYPPSS-FSEPLKDFLSKCFVKNMYKRPTADQLLKHVWINS</Hsp_hseq>
      <Hsp_midline>+  Q  L +K++H   V+HRDIKA NI L+ +N+ +KL DFG++ I+ ++   A T  GT  +++PEI  N   +  SDIWSLG  + E+ T N P+   +  ++   +   +Y P SS +S  ++  L++    N   RP+ + +L   +++S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.2705</Hsp_bit-score>
      <Hsp_score>212</Hsp_score>
      <Hsp_evalue>3.34685e-18</Hsp_evalue>
      <Hsp_query-from>8</Hsp_query-from>
      <Hsp_query-to>451</Hsp_query-to>
      <Hsp_hit-from>182</Hsp_hit-from>
      <Hsp_hit-to>324</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>148</Hsp_align-len>
      <Hsp_qseq>FPHAQVLNWFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYKPLSSRYSYDIRSVLAQMLKTNPRNR</Hsp_qseq>
      <Hsp_hseq>FPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILL-DKNGHIKITDFGFAKYVPD---VTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELR-FPPFFNEDVKDLLSRLITRDLSQR</Hsp_hseq>
      <Hsp_midline>FP+     +  ++CLA++++H + +++RD+K +NI L + N  IK+ DFG A+ + +   +  T  GTP Y++PE+    PYN   D WS G ++YE+     PF  ++      KI     +     ++ D++ +L++++  +   R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.8113</Hsp_bit-score>
      <Hsp_score>216</Hsp_score>
      <Hsp_evalue>3.51947e-18</Hsp_evalue>
      <Hsp_query-from>32</Hsp_query-from>
      <Hsp_query-to>517</Hsp_query-to>
      <Hsp_hit-from>157</Hsp_hit-from>
      <Hsp_hit-to>316</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>163</Hsp_align-len>
      <Hsp_qseq>WFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNN-KSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYKPLSSRYSYDIRSVLAQMLKTNPRNRPSINTILCKCFLSSRIQKFLGP</Hsp_qseq>
      <Hsp_hseq>FFQQIISAVEYCHRHKIVHRDLKPENLLL-DEHLNVKIADFGLSNIMTDGNFLKTSC-GSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYT-LPKFLSPGAAGLIKRMLIVNPLNRISIHEIMQDDWFKVDLPEYLLP</Hsp_hseq>
      <Hsp_midline>+F QI  AV++ H  K++HRD+K +N+ L + + ++K+ DFG++ I+T+   L  +C G+P Y +PE+     Y   + D+WS G +LY +     PF+  S+  L   I  G Y  L    S     ++ +ML  NP NR SI+ I+   +    + ++L P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.1965</Hsp_bit-score>
      <Hsp_score>217</Hsp_score>
      <Hsp_evalue>4.10806e-18</Hsp_evalue>
      <Hsp_query-from>17</Hsp_query-from>
      <Hsp_query-to>622</Hsp_query-to>
      <Hsp_hit-from>147</Hsp_hit-from>
      <Hsp_hit-to>369</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>230</Hsp_align-len>
      <Hsp_qseq>AQVLNWFVQICLAVKHIHDRKVLHRDIKAQNIFLTN--------------------NNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGS---YKPLSSRYSYDIRSVLAQMLKTNPRNRPSI-----NTILCKCFLSSRIQKFLGPELYNEEFSHTVIHSKKAVSGQRSKLAQQGKAPRAN</Hsp_qseq>
      <Hsp_hseq>AFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNT-SLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVVFEMCCGTPPFRASNHLELFKKIKRANDVITFPSYCNIEPELKELICSLLTFDPAQRIGFEEFFANKVVNEDLSSYELEDDL-PEL--ESKSKGIVESNMFVS---EYLSKQPKSPNSN</Hsp_hseq>
      <Hsp_midline>A VL++  Q+  A+K +  + ++HRDIK QN+ L+                     N   +K+ DFG AR L NT  LA T  G+P Y++PEI     YN K+D+WS+G V++E+C    PF  ++   L  KI + +     P       +++ ++  +L  +P  R        N ++ +   S  ++  L PEL  E  S  ++ S   VS     L++Q K+P +N</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.4261</Hsp_bit-score>
      <Hsp_score>215</Hsp_score>
      <Hsp_evalue>6.74556e-18</Hsp_evalue>
      <Hsp_query-from>41</Hsp_query-from>
      <Hsp_query-to>457</Hsp_query-to>
      <Hsp_hit-from>302</Hsp_hit-from>
      <Hsp_hit-to>456</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>156</Hsp_align-len>
      <Hsp_qseq>QICLAVKHIHDRKVLHRDIKAQNIFLTNNNSS-IKLGDFGIARILTNTMELARTCIGTPYYLSPEIC-------------ENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSY--KPLSS-RYSYDIRSVLAQMLKTNPRNRPS</Hsp_qseq>
      <Hsp_hseq>QILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNG-SFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGPLKDFRISEEARDFIDSLLQVDPNNRST</Hsp_hseq>
      <Hsp_midline>QI  A+K+IH   + HRD+K  NI +  ++   +K+ DFG+A++  N     +T  GT  Y++PE+              E   Y++  D+WS+GC++Y + T + PF G++   L  +I +GSY   PL   R S + R  +  +L+ +P NR +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.6557</Hsp_bit-score>
      <Hsp_score>213</Hsp_score>
      <Hsp_evalue>1.05644e-17</Hsp_evalue>
      <Hsp_query-from>8</Hsp_query-from>
      <Hsp_query-to>499</Hsp_query-to>
      <Hsp_hit-from>551</Hsp_hit-from>
      <Hsp_hit-to>716</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>167</Hsp_align-len>
      <Hsp_qseq>FPHAQVLNWFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILT--NTMELARTCI-GTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYKPLSSRYSYDIRSVLAQMLKTNPRNRPSINTILCKCFLSSRI</Hsp_qseq>
      <Hsp_hseq>FEESLITNFTRQILIGVAYLHKKNIIHRDIKGANI-LIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKIGTNTTPEIPSWATSEGKNFLRKAFELDYQYRPSALELLQHPWLDAHI</Hsp_hseq>
      <Hsp_midline>F  + + N+  QI + V ++H + ++HRDIK  NI L +    +K+ DFGI++ L+  N  +  R  + G+ +++SPE+ +      K+DIWS GCV+ E+ T  HPF   S    + KI   +   + S  + + ++ L +  + + + RPS   +L   +L + I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.9593</Hsp_bit-score>
      <Hsp_score>206</Hsp_score>
      <Hsp_evalue>1.68656e-17</Hsp_evalue>
      <Hsp_query-from>29</Hsp_query-from>
      <Hsp_query-to>451</Hsp_query-to>
      <Hsp_hit-from>206</Hsp_hit-from>
      <Hsp_hit-to>343</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>141</Hsp_align-len>
      <Hsp_qseq>NWFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYKPLSSRYSYDIRSVLAQMLKTNPRNR</Hsp_qseq>
      <Hsp_hseq>DYIYQIANALDYMHKKNIIHRDIKPENILIGFNNV-IKLTDFGWS-IINPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIK-MPSNISQDAQDLILKLLKYDPKDR</Hsp_hseq>
      <Hsp_midline>++  QI  A+ ++H + ++HRDIK +NI +  NN  IKL DFG + I+       +T  GT  YLSPE+ E+  Y++  D W+LG + +EL T   PFE         +I     K + S  S D + ++ ++LK +P++R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.1889</Hsp_bit-score>
      <Hsp_score>204</Hsp_score>
      <Hsp_evalue>2.71537e-17</Hsp_evalue>
      <Hsp_query-from>8</Hsp_query-from>
      <Hsp_query-to>451</Hsp_query-to>
      <Hsp_hit-from>165</Hsp_hit-from>
      <Hsp_hit-to>307</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>150</Hsp_align-len>
      <Hsp_qseq>FPHAQVLNWFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGS--YKPLSSRYSYDIRSVLAQMLKTNPRNR</Hsp_qseq>
      <Hsp_hseq>FPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILL-DRNGHIKITDFGFAK---EVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPY---FHPDVVDLLSKLITADLTRR</Hsp_hseq>
      <Hsp_midline>FP+     +  ++ LA++++H   +++RD+K +NI L + N  IK+ DFG A+       +  T  GTP Y++PE+    PYN   D WSLG ++YE+     PF   +      KI QG   Y P    +  D+  +L++++  +   R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.5741</Hsp_bit-score>
      <Hsp_score>205</Hsp_score>
      <Hsp_evalue>2.87109e-17</Hsp_evalue>
      <Hsp_query-from>8</Hsp_query-from>
      <Hsp_query-to>322</Hsp_query-to>
      <Hsp_hit-from>183</Hsp_hit-from>
      <Hsp_hit-to>283</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>105</Hsp_align-len>
      <Hsp_qseq>FPHAQVLNWFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPF</Hsp_qseq>
      <Hsp_hseq>FPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILL-DKNGHIKITDFGFAKYVP---DVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPF</Hsp_hseq>
      <Hsp_midline>FP+     +  ++CLA++++H + +++RD+K +NI L + N  IK+ DFG A+ +    ++  T  GTP Y++PE+    PYN   D WS G ++YE+     PF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.1149</Hsp_bit-score>
      <Hsp_score>209</Hsp_score>
      <Hsp_evalue>3.31543e-17</Hsp_evalue>
      <Hsp_query-from>41</Hsp_query-from>
      <Hsp_query-to>487</Hsp_query-to>
      <Hsp_hit-from>232</Hsp_hit-from>
      <Hsp_hit-to>391</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>162</Hsp_align-len>
      <Hsp_qseq>QICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARIL----TNTME---------LARTCIGTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYKPLSSRYSYDIRSVLAQMLKTNPRNRPSINTILCKCFL</Hsp_qseq>
      <Hsp_hseq>QIIDAVDSLHNIGIIHRDIKPENILL-DKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKIQY-AFTAGFPQIVKDLVKKLLVRDPNDRLTIKQIKAHLFF</Hsp_hseq>
      <Hsp_midline>QI  AV  +H+  ++HRDIK +NI L + N  +KL DFG A+IL    +NT +          +++ +GT  Y+SPE+  +   +++ DIW+ GC+LY++     PF+  +      K+ +  Y   ++ +   ++ ++ ++L  +P +R +I  I    F </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.9593</Hsp_bit-score>
      <Hsp_score>206</Hsp_score>
      <Hsp_evalue>7.09546e-17</Hsp_evalue>
      <Hsp_query-from>32</Hsp_query-from>
      <Hsp_query-to>451</Hsp_query-to>
      <Hsp_hit-from>518</Hsp_hit-from>
      <Hsp_hit-to>655</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>141</Hsp_align-len>
      <Hsp_qseq>WFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEIC-ENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYKPLSSRYSYDIRSVLAQMLKTNPRNR</Hsp_qseq>
      <Hsp_hseq>YIAELVLALEHLHDNDIVYRDLKPENILL-DANGNIALCDFGLSK--ADLKDRTNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNRNPKHR</Hsp_hseq>
      <Hsp_midline>+  ++ LA++H+HD  +++RD+K +NI L + N +I L DFG+++   +  +   T  GT  YL+PE+  +   Y    D WSLG +++E+C    PF   + + +  KI  G  K      S + RS +  +L  NP++R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.9593</Hsp_bit-score>
      <Hsp_score>206</Hsp_score>
      <Hsp_evalue>7.39701e-17</Hsp_evalue>
      <Hsp_query-from>41</Hsp_query-from>
      <Hsp_query-to>490</Hsp_query-to>
      <Hsp_hit-from>676</Hsp_hit-from>
      <Hsp_hit-to>826</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>154</Hsp_align-len>
      <Hsp_qseq>QICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPF-EGNSLRHLVMKICQGSYK---PLSSRYSYDIRSVLAQMLKTNPRNRPSINTILCKCFLS</Hsp_qseq>
      <Hsp_hseq>ETCQGLKFLHDKHIIHRDIKSDNVLL-DTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATNGTPKLKHPES--LSLEIKRFLSVCLCVDVRYRASTEELLHHGFFN</Hsp_hseq>
      <Hsp_midline>+ C  +K +HD+ ++HRDIK+ N+ L +  + +K+ DFG    LT+      T +GTPY+++PE+ +   Y+ K D+WSLG +  E+     P+   + L+ L +    G+ K   P S   S +I+  L+  L  + R R S   +L   F +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.6481</Hsp_bit-score>
      <Hsp_score>200</Hsp_score>
      <Hsp_evalue>1.92497e-16</Hsp_evalue>
      <Hsp_query-from>35</Hsp_query-from>
      <Hsp_query-to>472</Hsp_query-to>
      <Hsp_hit-from>309</Hsp_hit-from>
      <Hsp_hit-to>475</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>169</Hsp_align-len>
      <Hsp_qseq>FVQICLAVKHIHDRKVLHRDIKAQNIFLT----NNNSSIKLG--------------DFGIARILTNTMELARTCIGTPYYLSPEICENCPYNNKSDIWSLGCVLYE-LCTLNHPFEGN----SLRHLVMKICQGSYKPLSSRYSYDIRSVLAQMLKTNPRNRPSINTIL</Hsp_qseq>
      <Hsp_hseq>FKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAK-FTGEMQFTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVILYVCLCGF-PPFSDQLGPPSLKEQILQAKYAFYSPYWDKIDDSVLHLISNLLVLNPDERYNIDEAL</Hsp_hseq>
      <Hsp_midline>F Q+   +K++H++ ++HRDIK +NI L      N S ++LG              DFG+A+  T  M+   T  GTP Y++PE+     Y +K D+WS G +LY  LC    PF       SL+  +++     Y P   +    +  +++ +L  NP  R +I+  L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.8777</Hsp_bit-score>
      <Hsp_score>198</Hsp_score>
      <Hsp_evalue>3.51439e-16</Hsp_evalue>
      <Hsp_query-from>20</Hsp_query-from>
      <Hsp_query-to>526</Hsp_query-to>
      <Hsp_hit-from>324</Hsp_hit-from>
      <Hsp_hit-to>501</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>181</Hsp_align-len>
      <Hsp_qseq>QVLNWFVQICL-AVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLR------HLVMKIC----QGSYKPLSS-RYSYDIRSVLAQMLKTNPRNRPSINTILCKCFLSSRIQKFLGPELY</Hsp_qseq>
      <Hsp_hseq>KVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILL-NENGQVKLCDFGVSGEAVNS--LATTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANGKFPCSSEKMAANIAPFELLMWILTFTPELKDEPESNIIWSPSFKSFIDYCLKKDSRERPSPRQMINHPWIKGQMKKNVNMEKF</Hsp_hseq>
      <Hsp_midline>+VL    +  L  + ++H++KV+HRDIK QNI L N N  +KL DFG++    N+  LA T  GT +Y++PE  +  PY+  SD+WSLG  + E+     P     +        L+M I     +   +P S+  +S   +S +   LK + R RPS   ++   ++  +++K +  E +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.7962</Hsp_bit-score>
      <Hsp_score>190</Hsp_score>
      <Hsp_evalue>7.70993e-16</Hsp_evalue>
      <Hsp_query-from>23</Hsp_query-from>
      <Hsp_query-to>358</Hsp_query-to>
      <Hsp_hit-from>113</Hsp_hit-from>
      <Hsp_hit-to>224</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>113</Hsp_align-len>
      <Hsp_qseq>VLNWFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCP-YNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKI</Hsp_qseq>
      <Hsp_hseq>VKKFMMQLCKGIAYCHSHRILHRDLKPQNL-LINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKI</Hsp_hseq>
      <Hsp_midline>V  + +Q+C  + + H  ++LHRD+K QN+ L N + ++KLGDFG+AR     +      I T +Y +PE+      Y+   D WS+GC+  E+C     F G+S    + KI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.1073</Hsp_bit-score>
      <Hsp_score>196</Hsp_score>
      <Hsp_evalue>1.18787e-15</Hsp_evalue>
      <Hsp_query-from>44</Hsp_query-from>
      <Hsp_query-to>517</Hsp_query-to>
      <Hsp_hit-from>253</Hsp_hit-from>
      <Hsp_hit-to>405</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>159</Hsp_align-len>
      <Hsp_qseq>ICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNN-KSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYKPLSSRYSYDIRSVLAQMLKTNPRNRPSINTILCKCFLSSRIQKFLGP</Hsp_qseq>
      <Hsp_hseq>IASALIYLHANNIVHRDLKIENIMIS-DSSEIKIIDFGLSNIYDSRKQLHTFC-GSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKIKQGKVE-YPQHLSIEVISLLSKMLVVDPKRRATLKQVVEHHWM---VRGFNGP</Hsp_hseq>
      <Hsp_midline>I  A+ ++H   ++HRD+K +NI ++ ++S IK+ DFG++ I  +  +L   C G+ Y+ +PE+ +  PY   + D+WS G VL+ L     PF+  +   L  KI QG  +      S ++ S+L++ML  +P+ R ++  ++   ++   ++ F GP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.9518</Hsp_bit-score>
      <Hsp_score>193</Hsp_score>
      <Hsp_evalue>1.86115e-15</Hsp_evalue>
      <Hsp_query-from>41</Hsp_query-from>
      <Hsp_query-to>493</Hsp_query-to>
      <Hsp_hit-from>296</Hsp_hit-from>
      <Hsp_hit-to>480</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>189</Hsp_align-len>
      <Hsp_qseq>QICLAVKHIHDRKVLHRDIKAQNIFL--------------------TNNNSSI-------------KLGDFGIARIL--TNTMELARTCIGTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSY---KPLSSRYSYDIRSVLAQMLKTNPRNRPSINTILCKCFLSS</Hsp_qseq>
      <Hsp_hseq>QLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKNT----KTPCGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTMLCGFPPFYDEKIDTLTEKISRGEYTFLKPWWDEISAGAKNAVAKLLELEPSKRYDIDQFLDDPWLNT</Hsp_hseq>
      <Hsp_midline>Q+ LAVKH+H   V+HRDIK +N+                      T  +  I             KL DFG+++ +   NT    +T  GT  Y +PE+ ++  Y+ K D+W +GCVLY +     PF    +  L  KI +G Y   KP     S   ++ +A++L+  P  R  I+  L   +L++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YNL020C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:595623:597539:-1 gene:YNL020C transcript:YNL020C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ARK1 description:Serine/threonine protein kinase; involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis; ARK1 has a paralog, PRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004965]</Hit_def>
  <Hit_accession>YNL020C</Hit_accession>
  <Hit_len>638</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.9518</Hsp_bit-score>
      <Hsp_score>193</Hsp_score>
      <Hsp_evalue>2.22767e-15</Hsp_evalue>
      <Hsp_query-from>20</Hsp_query-from>
      <Hsp_query-to>472</Hsp_query-to>
      <Hsp_hit-from>133</Hsp_hit-from>
      <Hsp_hit-to>293</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>167</Hsp_align-len>
      <Hsp_qseq>QVLNWFVQICLAVKHIHDRK--VLHRDIKAQNIFLTNNNSSIKLGDFG----IARILTNTMELARTCIG-----TPYYLSPEICE---NCPYNNKSDIWSLGCVLYELCTLNHPFE-GNSLRHLVMKICQGSYK-PLSSRYSYDIRSVLAQMLKTNPRNRPSINTIL</Hsp_qseq>
      <Hsp_hseq>EILQIMSQVTQGVAAMHALQPPLIHRDIKIENVLISANNE-YKLCDFGSVCGIIRPPRNSQELSYVQQDILKNTTAQYRSPEMIDTFRGLPIDEKSDIWALGIFLYKLCYYTTPFEKGGDL-----AILSGKFEFPLYPNYSEQLKGLIRDILVQDPRHRPNVYQLL</Hsp_hseq>
      <Hsp_midline>++L    Q+   V  +H  +  ++HRDIK +N+ ++ NN   KL DFG    I R   N+ EL+          T  Y SPE+ +     P + KSDIW+LG  LY+LC    PFE G  L      I  G ++ PL   YS  ++ ++  +L  +PR+RP++  +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.0258</Hsp_bit-score>
      <Hsp_score>188</Hsp_score>
      <Hsp_evalue>5.43057e-15</Hsp_evalue>
      <Hsp_query-from>38</Hsp_query-from>
      <Hsp_query-to>493</Hsp_query-to>
      <Hsp_hit-from>241</Hsp_hit-from>
      <Hsp_hit-to>416</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>178</Hsp_align-len>
      <Hsp_qseq>VQICLAVKHIHDRKVLHRDIKAQNIFL-----------------------TNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYK---PLSSRYSYDIRSVLAQMLKTNPRNRPSINTILCKCFLSS</Hsp_qseq>
      <Hsp_hseq>TQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLRNNT--AKTPCGTIEYVASEVFTSKRYSMKVDMWSIGCVLFTLLCGYPPFYEKNEKTLLKKISRGDYEFLAPWWDNISSGAKNAVTHLLEVDPNKRYDIDDFLNDPWLNS</Hsp_hseq>
      <Hsp_midline> Q+ +A+KH+H   ++HRD+K +N+                               +KL DFG+A+ L N    A+T  GT  Y++ E+  +  Y+ K D+WS+GCVL+ L     PF   + + L+ KI +G Y+   P     S   ++ +  +L+ +P  R  I+  L   +L+S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.6406</Hsp_bit-score>
      <Hsp_score>187</Hsp_score>
      <Hsp_evalue>7.6339e-15</Hsp_evalue>
      <Hsp_query-from>32</Hsp_query-from>
      <Hsp_query-to>544</Hsp_query-to>
      <Hsp_hit-from>301</Hsp_hit-from>
      <Hsp_hit-to>480</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>188</Hsp_align-len>
      <Hsp_qseq>WFVQICLA---------VKHIHDR-KVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPFEG-NSLRHLVMKICQGSYKPLSSR------YSYDIRSVLAQMLKTNPRNRPSINTILCKCFLSSRIQKFLGPELYNEEFSH</Hsp_qseq>
      <Hsp_hseq>WFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNV-LINSKGQIKLCDFGVSKKLINS--IADTFVGTSTYMSPERIQGNVYSIKGDVWSLGLMIIELVTGEFPLGGHNDTPDGILDLLQRIVNEPSPRLPKDRIYSKEMTDFVNRCCIKNERERSSIHELLHHDL----IMKYVSPS-KDDKFRH</Hsp_hseq>
      <Hsp_midline>WF ++ ++         + H++ + K++HRDIK  N+ L N+   IKL DFG+++ L N+  +A T +GT  Y+SPE  +   Y+ K D+WSLG ++ EL T   P  G N     ++ + Q      S R      YS ++   + +    N R R SI+ +L        I K++ P   +++F H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.8702</Hsp_bit-score>
      <Hsp_score>185</Hsp_score>
      <Hsp_evalue>1.17375e-14</Hsp_evalue>
      <Hsp_query-from>8</Hsp_query-from>
      <Hsp_query-to>472</Hsp_query-to>
      <Hsp_hit-from>133</Hsp_hit-from>
      <Hsp_hit-to>294</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>162</Hsp_align-len>
      <Hsp_qseq>FPHAQVLNWFVQICLAVKHIHDRKVLHRDIKAQNIFLTN--NNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSY-----KPLSSRYSYDIRSVLAQMLKTNPRNRPSINTIL</Hsp_qseq>
      <Hsp_hseq>FTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAELL</Hsp_hseq>
      <Hsp_midline>F     +   V+I  AVK++H + ++HRD+K +N+   +  + S + + DFGIA+ L +  EL     G+  Y++PE+     +    DIWS+G + Y L      F    ++  + +   G Y     +P     S   +  + + L  +P  RP+   +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.6406</Hsp_bit-score>
      <Hsp_score>187</Hsp_score>
      <Hsp_evalue>1.72347e-14</Hsp_evalue>
      <Hsp_query-from>32</Hsp_query-from>
      <Hsp_query-to>469</Hsp_query-to>
      <Hsp_hit-from>283</Hsp_hit-from>
      <Hsp_hit-to>437</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>157</Hsp_align-len>
      <Hsp_qseq>WFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNT-----------MELARTCIGTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYKPLSSRYSYDIRSVLAQMLKTNPRNRPSINTI</Hsp_qseq>
      <Hsp_hseq>YAAQIIDAIDYLHSNGIIHRDIKPENILL-DGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKVQY-AFTPGFPLIIRDLVKKILVKNLDRRLTISQI</Hsp_hseq>
      <Hsp_midline>+  QI  A+ ++H   ++HRDIK +NI L +    IKL DFG A++L  T              +++ +GT  Y+SPE+  +   + + DIW+ GC+L+++     PF+  +      K+ +  Y   +  +   IR ++ ++L  N   R +I+ I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.485</Hsp_bit-score>
      <Hsp_score>184</Hsp_score>
      <Hsp_evalue>1.9421e-14</Hsp_evalue>
      <Hsp_query-from>2</Hsp_query-from>
      <Hsp_query-to>328</Hsp_query-to>
      <Hsp_hit-from>276</Hsp_hit-from>
      <Hsp_hit-to>383</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>110</Hsp_align-len>
      <Hsp_qseq>VFFPHAQVLNWFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPE-ICENCPYNNKSDIWSLGCVLYELCTLNHPFEG</Hsp_qseq>
      <Hsp_hseq>VQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNI-LIDNQGNLKITDFGLARKMNSRADYTNRVI-TLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQG</Hsp_hseq>
      <Hsp_midline>V   H+Q  + F Q+ L ++++HD K+LHRD+K  NI L +N  ++K+ DFG+AR + +  +     I T +Y  PE +     Y  + D+W  GC+L EL      F+G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.2554</Hsp_bit-score>
      <Hsp_score>186</Hsp_score>
      <Hsp_evalue>1.98033e-14</Hsp_evalue>
      <Hsp_query-from>53</Hsp_query-from>
      <Hsp_query-to>490</Hsp_query-to>
      <Hsp_hit-from>726</Hsp_hit-from>
      <Hsp_hit-to>872</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>150</Hsp_align-len>
      <Hsp_qseq>AVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGI-ARILTNTMELARTC-IGTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPFEGNS-LRHLVMKICQGSYK-PLSSRYSYDIRSVLAQMLKTNPRNRPSINTILCKCFLS</Hsp_qseq>
      <Hsp_hseq>GLEFLHSKGVLHRDIKSDNILLSME-GDIKLTDFGFCAQI--NELNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPPYLNETPLRALYLIATNGTPKLKEPENLSSSLKKFLDWCLCVEPEDRASATELLHDEYIT</Hsp_hseq>
      <Hsp_midline> ++ +H + VLHRDIK+ NI L+     IKL DFG  A+I  N + L RT  +GTPY+++PE+     Y  K DIWSLG ++ E+     P+   + LR L +    G+ K       S  ++  L   L   P +R S   +L   +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.8702</Hsp_bit-score>
      <Hsp_score>185</Hsp_score>
      <Hsp_evalue>2.73584e-14</Hsp_evalue>
      <Hsp_query-from>38</Hsp_query-from>
      <Hsp_query-to>511</Hsp_query-to>
      <Hsp_hit-from>1285</Hsp_hit-from>
      <Hsp_hit-to>1457</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>177</Hsp_align-len>
      <Hsp_qseq>VQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIAR----ILTNTMELARTCIGTPYYLSPEICENCP-YNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYKPLSSRYSYDI-----RSVLAQMLKTNPRNRPSINTILCK---------CFLSSRIQKFL</Hsp_qseq>
      <Hsp_hseq>TQVLKGLAYLHSKGILHRDMKADNLLL-DQDGICKISDFGISRKSKDIYSNSDMTMR---GTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANELLSHPFSEVNETFNFKSTRLAKFI</Hsp_hseq>
      <Hsp_midline> Q+   + ++H + +LHRD+KA N+ L + +   K+ DFGI+R    I +N+    R   GT ++++PE+ +    Y+ K DIWSLGC++ E+     P+    +   + KI +    P     +  +     R+ L    + NP  RP+ N +L            F S+R+ KF+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.8702</Hsp_bit-score>
      <Hsp_score>185</Hsp_score>
      <Hsp_evalue>2.81488e-14</Hsp_evalue>
      <Hsp_query-from>44</Hsp_query-from>
      <Hsp_query-to>472</Hsp_query-to>
      <Hsp_hit-from>232</Hsp_hit-from>
      <Hsp_hit-to>372</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>144</Hsp_align-len>
      <Hsp_qseq>ICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNN-KSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYKPLSSRYSYDIRSVLAQMLKTNPRNRPSINTIL</Hsp_qseq>
      <Hsp_hseq>IASALQYLHANNIVHRDLKIENIMIS-SSGEIKIIDFGLSNIFDYRKQLHTFC-GSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVD-YPSHLSIEVISLLTRMIVVDPLRRATLKNVV</Hsp_hseq>
      <Hsp_midline>I  A++++H   ++HRD+K +NI ++ ++  IK+ DFG++ I     +L   C G+ Y+ +PE+ +  PY   + DIWS G VLY L     PF+  +   L  KI +G      S  S ++ S+L +M+  +P  R ++  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.7886</Hsp_bit-score>
      <Hsp_score>177</Hsp_score>
      <Hsp_evalue>6.69794e-14</Hsp_evalue>
      <Hsp_query-from>14</Hsp_query-from>
      <Hsp_query-to>364</Hsp_query-to>
      <Hsp_hit-from>119</Hsp_hit-from>
      <Hsp_hit-to>240</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>65</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>125</Hsp_align-len>
      <Hsp_qseq>HAQVLNWFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIG-------TPYYLSPEICENC-PYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQ</Hsp_qseq>
      <Hsp_hseq>HVQYFTY--QILRALKSIHSAQVIHRDIKPSNLLL-NSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILE</Hsp_hseq>
      <Hsp_midline>H Q   +  QI  A+K IH  +V+HRDIK  N+ L N+N  +K+ DFG+AR L ++ +   T +G       T +Y +PEI      Y    DIWS GC+L E+ +    F G    H +  I +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.7886</Hsp_bit-score>
      <Hsp_score>177</Hsp_score>
      <Hsp_evalue>1.89959e-13</Hsp_evalue>
      <Hsp_query-from>32</Hsp_query-from>
      <Hsp_query-to>463</Hsp_query-to>
      <Hsp_hit-from>450</Hsp_hit-from>
      <Hsp_hit-to>591</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>146</Hsp_align-len>
      <Hsp_qseq>WFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYKPL--SSRYSYDIRSVLAQMLKTNPRNRPSIN</Hsp_qseq>
      <Hsp_hseq>YTAELLCALDNLHKLDVVYRDLKPENILL-DYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQ---EPLVFPDGFDRDAKDLLIGLLSRDPTRRLGYN</Hsp_hseq>
      <Hsp_midline>+  ++  A+ ++H   V++RD+K +NI L +    I L DFG+ ++     +   T  GTP YL+PE+     Y    D W+LG +LYE+ T   P+    +  +  KI Q   +PL     +  D + +L  +L  +P  R   N</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.7886</Hsp_bit-score>
      <Hsp_score>177</Hsp_score>
      <Hsp_evalue>2.19713e-13</Hsp_evalue>
      <Hsp_query-from>32</Hsp_query-from>
      <Hsp_query-to>451</Hsp_query-to>
      <Hsp_hit-from>929</Hsp_hit-from>
      <Hsp_hit-to>1066</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>144</Hsp_align-len>
      <Hsp_qseq>WFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYKPLSSRYSYDIRSVLAQ----MLKTNPRNR</Hsp_qseq>
      <Hsp_hseq>YAAEVLLALKYFHDNGVIYRDLKLENILLTPE-GHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAIL--TDEPL---YPIDMAGEIVQIFQGLLTKDPEKR</Hsp_hseq>
      <Hsp_midline>+  ++ LA+K+ HD  V++RD+K +NI LT     IK+ D+G+ +          T  GTP +++PEI +   Y    D W+ G +LY++     PF G+    +   I   + +PL   Y  D+   + Q    +L  +P  R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.4034</Hsp_bit-score>
      <Hsp_score>176</Hsp_score>
      <Hsp_evalue>2.66671e-13</Hsp_evalue>
      <Hsp_query-from>8</Hsp_query-from>
      <Hsp_query-to>463</Hsp_query-to>
      <Hsp_hit-from>439</Hsp_hit-from>
      <Hsp_hit-to>588</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>154</Hsp_align-len>
      <Hsp_qseq>FPHAQVLNWFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYKPLSSRYSYD--IRSVLAQMLKTNPRNRPSIN</Hsp_qseq>
      <Hsp_hseq>FSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILL-DYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQ---QPLLFPDGFDPAAKDLLIGLLSRDPSRRLGVN</Hsp_hseq>
      <Hsp_midline>F  A+   +  ++  A+  +H   V++RD+K +NI L +    I L DFG+ ++     +   T  GTP YL+PEI     Y    D W+LG +LYE+ T   P+   ++  +  KI Q   +PL     +D   + +L  +L  +P  R  +N</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>4.06282e-13</Hsp_evalue>
      <Hsp_query-from>41</Hsp_query-from>
      <Hsp_query-to>334</Hsp_query-to>
      <Hsp_hit-from>273</Hsp_hit-from>
      <Hsp_hit-to>389</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>117</Hsp_align-len>
      <Hsp_qseq>QICLAVKHIHDRKVLHRDIKAQNIFLTNNN--SSIKLGDFGIARILTNTMELARTCIGTPYYLSPEI-----------------CENCPYNNKSDIWSLGCVLYELCTLNHPFEGNS</Hsp_qseq>
      <Hsp_hseq>QILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGISPFYGDG</Hsp_hseq>
      <Hsp_midline>QI  A+ ++HD+ ++HRD+K  NI L      + I L DFGIA+ L +  E   T +GTP Y +PE+                  E   Y++K D+WSLG + + + T   PF G+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>7.61738e-13</Hsp_evalue>
      <Hsp_query-from>35</Hsp_query-from>
      <Hsp_query-to>325</Hsp_query-to>
      <Hsp_hit-from>335</Hsp_hit-from>
      <Hsp_hit-to>446</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>113</Hsp_align-len>
      <Hsp_qseq>FVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSS---------------IKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNNK-SDIWSLGCVLYELCTLNHPFE</Hsp_qseq>
      <Hsp_hseq>FTEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLCKKIENN-EMCTARCGSEDYVSPEILMGVPYDGHLSDTWALGVILYSLFEDRLPFD</Hsp_hseq>
      <Hsp_midline>F ++ LAVK++H+  ++HRD+K +NI L  +                  I+L DFG+ + + N  E+     G+  Y+SPEI    PY+   SD W+LG +LY L     PF+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>8.44766e-13</Hsp_evalue>
      <Hsp_query-from>35</Hsp_query-from>
      <Hsp_query-to>487</Hsp_query-to>
      <Hsp_hit-from>816</Hsp_hit-from>
      <Hsp_hit-to>981</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>170</Hsp_align-len>
      <Hsp_qseq>FVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELAR--------------TCIGTPYYLSPEICENCP-YNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQG---SYKPLSSRYSYDI-RSVLAQMLKTNPRNRPSINTILCKCFL</Hsp_qseq>
      <Hsp_hseq>FRQILEALSYIHSQGIIHRDLKPMNIFI-DESRNVKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVLDGTGHYNEKIDMYSLGIIFFEMI---YPFSTGMERVNILKKLRSVSIEFPPDFDDNKMKVEKKIIRLLIDHDPNKRPGARTLLNSGWL</Hsp_hseq>
      <Hsp_midline>F QI  A+ +IH + ++HRD+K  NIF+ + + ++K+GDFG+A+ +  ++++ +              + IGT  Y++ E+ +    YN K D++SLG + +E+    +PF     R  ++K  +     + P        + + ++  ++  +P  RP   T+L   +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YBR059C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:356861:360187:-1 gene:YBR059C transcript:YBR059C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AKL1 description:Ser-Thr protein kinase; member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization [Source:SGD;Acc:S000000263]</Hit_def>
  <Hit_accession>YBR059C</Hit_accession>
  <Hit_len>1108</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.8626</Hsp_bit-score>
      <Hsp_score>172</Hsp_score>
      <Hsp_evalue>9.48789e-13</Hsp_evalue>
      <Hsp_query-from>14</Hsp_query-from>
      <Hsp_query-to>472</Hsp_query-to>
      <Hsp_hit-from>153</Hsp_hit-from>
      <Hsp_hit-to>314</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>167</Hsp_align-len>
      <Hsp_qseq>HAQVLNWFVQICLAVKHIHDRKV--LHRDIKAQNIFLTNNNSSIKLGDFGIAR----ILTNTMELARTCIG-----TPYYLSPEICE--NC-PYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYKPLSSRYSYDIRSVLAQMLKTNPRNRPSINTIL</Hsp_qseq>
      <Hsp_hseq>EAEIVKIMYDVALSISQMHYLPVSLIHRDIKIENVLVDAKNN-FKLADFGSTSTCFPIVTTHQDIALLTQNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGVFLYKLLFFTTPFEMTGQ----FAILHSKYEFPVNKYSSKLINLIIIMLAENPNLRPNIYQVL</Hsp_hseq>
      <Hsp_midline> A+++     + L++  +H   V  +HRDIK +N+ +   N+  KL DFG       I+T   ++A          TP Y SPE+ +   C P N KSDIW+LG  LY+L     PFE          I    Y+   ++YS  + +++  ML  NP  RP+I  +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>1.10016e-12</Hsp_evalue>
      <Hsp_query-from>32</Hsp_query-from>
      <Hsp_query-to>343</Hsp_query-to>
      <Hsp_hit-from>121</Hsp_hit-from>
      <Hsp_hit-to>229</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>110</Hsp_align-len>
      <Hsp_qseq>WFVQICLAVKHIH-DRKVLHRDIKAQNIFLTNNNSSIKLGDFGIA---RILTNTMELARTCIGTPYYLSPEIC--ENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRH</Hsp_qseq>
      <Hsp_hseq>YFQQLVSAINYLHVECGVAHRDIKPENILL-DKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQTPWELPSLEN</Hsp_hseq>
      <Hsp_midline>+F Q+  A+ ++H +  V HRDIK +NI L + N ++KL DFG+A   R    T+ ++    G+P Y++PE+   E   Y +++DIWS+G +L+ L T   P+E  SL +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>1.34059e-12</Hsp_evalue>
      <Hsp_query-from>35</Hsp_query-from>
      <Hsp_query-to>469</Hsp_query-to>
      <Hsp_hit-from>956</Hsp_hit-from>
      <Hsp_hit-to>1093</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>147</Hsp_align-len>
      <Hsp_qseq>FVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNNK-SDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYK-PLSSRYSYDIRSVLAQMLKTNPRNRPSINTI</Hsp_qseq>
      <Hsp_hseq>FKQVVASIKHLHDQGIVHRDIKDENV-IVDSHGFVKLIDFGSAAYIKSGP--FDVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLYTIIYKENPY------YNIDEILEGELRFDKSEHVSEECISLIKRILTREVDKRPTIDEI</Hsp_hseq>
      <Hsp_midline>F Q+  ++KH+HD+ ++HRDIK +N+ + +++  +KL DFG A  + +        +GT  Y +PE+     Y  K  DIW+LG +LY +    +P+      + + +I +G  +   S   S +  S++ ++L      RP+I+ I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>2.05982e-12</Hsp_evalue>
      <Hsp_query-from>32</Hsp_query-from>
      <Hsp_query-to>481</Hsp_query-to>
      <Hsp_hit-from>257</Hsp_hit-from>
      <Hsp_hit-to>416</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>161</Hsp_align-len>
      <Hsp_qseq>WFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELAR----------TCIGTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYKPLSSRY-SYDIRSVLAQMLKTNPRNRPSINTILCKC</Hsp_qseq>
      <Hsp_hseq>YAAEISCALRFLHTKGVVYRDLKPENCLL-NQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIPFYLSEGMKDILNALLKKETAKRWNVDKYWAKT</Hsp_hseq>
      <Hsp_midline>+  +I  A++ +H + V++RD+K +N  L N    + L DFG+++   N   +            + IGTP Y +PEI     Y+   D +SLGC+LY++     P+ G++ + ++ KI Q    P    Y S  ++ +L  +LK     R +++    K </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>3.83797e-12</Hsp_evalue>
      <Hsp_query-from>41</Hsp_query-from>
      <Hsp_query-to>334</Hsp_query-to>
      <Hsp_hit-from>116</Hsp_hit-from>
      <Hsp_hit-to>213</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>99</Hsp_align-len>
      <Hsp_qseq>QICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENC-PYNNKSDIWSLGCVLYELCTLNHPFEGNS</Hsp_qseq>
      <Hsp_hseq>QLLQGLAFCHENKILHRDLKPQNL-LINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTN</Hsp_hseq>
      <Hsp_midline>Q+   +   H+ K+LHRD+K QN+ L N    +KLGDFG+AR     +    + + T +Y +P++      Y+   DIWS GC+L E+ T    F G +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YPL026C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:500675:502183:-1 gene:YPL026C transcript:YPL026C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKS1 description:Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway; SKS1 has a paralog, VHS1, that arose from the whole genome duplication [Source:SGD;Acc:S000005947]</Hit_def>
  <Hit_accession>YPL026C</Hit_accession>
  <Hit_len>502</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>6.1239e-12</Hsp_evalue>
      <Hsp_query-from>35</Hsp_query-from>
      <Hsp_query-to>478</Hsp_query-to>
      <Hsp_hit-from>167</Hsp_hit-from>
      <Hsp_hit-to>330</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>176</Hsp_align-len>
      <Hsp_qseq>FVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELA-RTCIGTPYYLSPE---ICENCPYN-------------NKSDIWSLGCVLYELCTLNHPF------EGNSLRHL-----VMKICQGSYKPLSSRYSYDIRSVLAQMLKTNPRNRPSINTILCK</Hsp_qseq>
      <Hsp_hseq>FLQLCSALDHCHRLGIYHCDIKPENVLLDRNDNAY-LCDFGLS---TKSKYLAPNVCVGSSYYMAPERILYCLNTTTNGIHVDECCSSLPTDTGDIWSLGIILINLTCIRNPWLKAHQKEDNTFQHFANDNNVLK----KILPISD----ELFTVLTKILQLNPYTRIDMKTLMSE</Hsp_hseq>
      <Hsp_midline>F+Q+C A+ H H   + H DIK +N+ L  N+++  L DFG++   T +  LA   C+G+ YY++PE    C N   N             +  DIWSLG +L  L  + +P+      E N+ +H      V+K       P+S     ++ +VL ++L+ NP  R  + T++ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>6.30458e-12</Hsp_evalue>
      <Hsp_query-from>26</Hsp_query-from>
      <Hsp_query-to>358</Hsp_query-to>
      <Hsp_hit-from>114</Hsp_hit-from>
      <Hsp_hit-to>235</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>123</Hsp_align-len>
      <Hsp_qseq>LNWFV-QICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARIL----------TNTMELARTCIGTPYYLSPEI-CENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKI</Hsp_qseq>
      <Hsp_hseq>IQYFIYQTLRAVKVLHGSNVIHRDLKPSNL-LINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLI</Hsp_hseq>
      <Hsp_midline>+ +F+ Q   AVK +H   V+HRD+K  N+ L N+N  +K+ DFG+ARI+          T         + T +Y +PE+   +  Y+   D+WS GC+L EL      F G   RH ++ I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YDR247W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:956013:957398:1 gene:YDR247W transcript:YDR247W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VHS1 description:Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; VHS1 has a paralog, SKS1, that arose from the whole genome duplication [Source:SGD;Acc:S000002655]</Hit_def>
  <Hit_accession>YDR247W</Hit_accession>
  <Hit_len>461</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>8.09011e-12</Hsp_evalue>
      <Hsp_query-from>35</Hsp_query-from>
      <Hsp_query-to>472</Hsp_query-to>
      <Hsp_hit-from>166</Hsp_hit-from>
      <Hsp_hit-to>327</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>174</Hsp_align-len>
      <Hsp_qseq>FVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPE-----------------ICENCPYNNKSDIWSLGCVLYELCTLNHPF------EGNSLRHL-----VMKICQGSYKPLSSRYSYDIRSVLAQMLKTNPRNRPSINTIL</Hsp_qseq>
      <Hsp_hseq>FLQICSALNYCHEHGIYHCDIKPENLLL-DTEDNVFLCDFGLST--TSTYIKPNVCIGSSYYMPPERISFDGRVSSSKSGGHKLGKVCPSCN-GDLWSLGIILINLTCIRNPWLKADKTEDNTYYYFTKDPNILK----QILPLSD----DFYSLLSKILQVNPKNRMSLQELM</Hsp_hseq>
      <Hsp_midline>F+QIC A+ + H+  + H DIK +N+ L +   ++ L DFG++   T+T      CIG+ YY+ PE                 + + CP  N  D+WSLG +L  L  + +P+      E N+  +      ++K       PLS     D  S+L+++L+ NP+NR S+  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>9.62526e-12</Hsp_evalue>
      <Hsp_query-from>20</Hsp_query-from>
      <Hsp_query-to>343</Hsp_query-to>
      <Hsp_hit-from>119</Hsp_hit-from>
      <Hsp_hit-to>224</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>110</Hsp_align-len>
      <Hsp_qseq>QVLNWFV-QICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENC-PYNNKSDIWSLGCVLYELCTLNHPFEGNSLRH</Hsp_qseq>
      <Hsp_hseq>QFVQYFLYQILRGLKYVHSAGVIHRDLKPSNI-LINENCDLKICDFGLARIQDPQM---TGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVH</Hsp_hseq>
      <Hsp_midline>Q + +F+ QI   +K++H   V+HRD+K  NI L N N  +K+ DFG+ARI    M      + T YY +PEI      Y+ + DIWS GC+  E+      F G    H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>1.1784e-11</Hsp_evalue>
      <Hsp_query-from>35</Hsp_query-from>
      <Hsp_query-to>469</Hsp_query-to>
      <Hsp_hit-from>1211</Hsp_hit-from>
      <Hsp_hit-to>1348</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>147</Hsp_align-len>
      <Hsp_qseq>FVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNNK-SDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYK-PLSSRYSYDIRSVLAQMLKTNPRNRPSINTI</Hsp_qseq>
      <Hsp_hseq>FKQVVAGIKHLHDQGIVHRDIKDENV-IVDSKGFVKIIDFGSAAYVKSGP--FDVFVGTIDYAAPEVLGGNPYEGQPQDIWAIGILLYTVVFKENPF------YNIDEILEGDLKFNNAEEVSEDCIELIKSILNRCVPKRPTIDDI</Hsp_hseq>
      <Hsp_midline>F Q+   +KH+HD+ ++HRDIK +N+ + ++   +K+ DFG A  + +        +GT  Y +PE+    PY  +  DIW++G +LY +    +PF      + + +I +G  K   +   S D   ++  +L      RP+I+ I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>1.46591e-11</Hsp_evalue>
      <Hsp_query-from>35</Hsp_query-from>
      <Hsp_query-to>331</Hsp_query-to>
      <Hsp_hit-from>156</Hsp_hit-from>
      <Hsp_hit-to>255</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>101</Hsp_align-len>
      <Hsp_qseq>FVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENC-PYN-NKSDIWSLGCVLYELCTLNHPFEGN</Hsp_qseq>
      <Hsp_hseq>FSQLISGVHYIHSKGLVHRDLKLENLLL-DKNENLVITDFGFVNEFCSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPWDDD</Hsp_hseq>
      <Hsp_midline>F Q+   V +IH + ++HRD+K +N+ L + N ++ + DFG      +  EL +T  G+P Y +PE+  +  PY   K+DIWS G +LY +     P++ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>2.85083e-11</Hsp_evalue>
      <Hsp_query-from>38</Hsp_query-from>
      <Hsp_query-to>553</Hsp_query-to>
      <Hsp_hit-from>189</Hsp_hit-from>
      <Hsp_hit-to>369</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>187</Hsp_align-len>
      <Hsp_qseq>VQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENC--------PYN-NKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYKPLSSRYS---YDIRSVLAQMLKTNPRNRPSINTILCKCFLSSRIQKFLGPELYN---EEFSHTVI</Hsp_qseq>
      <Hsp_hseq>TQIMDAIEYVHNKGIYHRDIKPENILISGIDWTIKLTDWGLATTDKTSMD---RNVGSERYMSPELFDSNLDIKERKEPYDCAKVDLWAMGIVFLNIVFHKNPFSIANQSDKSFCYFAANREALFDVFSTMAYDFFQVLRYSLTIDPANR---DLKMMRTELQNLSEYTLDDEYYNNLDEGYEETMI</Hsp_hseq>
      <Hsp_midline> QI  A++++H++ + HRDIK +NI ++  + +IKL D+G+A     +M+     +G+  Y+SPE+ ++         PY+  K D+W++G V   +    +PF   +           + + L   +S   YD   VL   L  +P NR   +  + +  L +  +  L  E YN   E +  T+I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>3.03764e-11</Hsp_evalue>
      <Hsp_query-from>41</Hsp_query-from>
      <Hsp_query-to>382</Hsp_query-to>
      <Hsp_hit-from>176</Hsp_hit-from>
      <Hsp_hit-to>305</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>131</Hsp_align-len>
      <Hsp_qseq>QICLAVKHIHDRKVLHRDIKAQNIFLT----------------NNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNNKS-DIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYKPL</Hsp_qseq>
      <Hsp_hseq>QILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVENKNPYT-AYVSTRWYRSPEILLRSGYYSKPLDIWAFGCVAVEVTVFRALFPGANEIDQIWKILEVLGTPI</Hsp_hseq>
      <Hsp_midline>QI   +KHIH+    HRD+K +NI +T                 +N  IKL DFG+AR + N        + T +Y SPEI     Y +K  DIW+ GCV  E+      F G +    + KI +    P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>3.79204e-11</Hsp_evalue>
      <Hsp_query-from>35</Hsp_query-from>
      <Hsp_query-to>487</Hsp_query-to>
      <Hsp_hit-from>156</Hsp_hit-from>
      <Hsp_hit-to>313</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>162</Hsp_align-len>
      <Hsp_qseq>FVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPE--ICENCPYNNKSDIWSLGCVLYELCTLNHPFE-------GNSLRHLVMKICQGSYKPLS-SRYSYDI-RSVLAQMLKTNPRNRPSINTILCKCFL</Hsp_qseq>
      <Hsp_hseq>FAQLISGVNYMHYKGLVHRDLKLENLLL-DKHENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARLYKYITQ---TPLKFPEYITPIPRDLLRRILVPNPRRRINLQTIKRHVWL</Hsp_hseq>
      <Hsp_midline>F Q+   V ++H + ++HRD+K +N+ L + + ++ + DFG         EL +T  G+P Y +PE  +        K+D+WS G +LY +     P++       G+ +  L   I Q    PL    Y   I R +L ++L  NPR R ++ TI    +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>4.81356e-11</Hsp_evalue>
      <Hsp_query-from>17</Hsp_query-from>
      <Hsp_query-to>457</Hsp_query-to>
      <Hsp_hit-from>462</Hsp_hit-from>
      <Hsp_hit-to>613</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>156</Hsp_align-len>
      <Hsp_qseq>AQVLNWFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEIC-----ENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMK---ICQGSYKPL-SSRYSYDIRSVLAQMLKTNPRNRPS</Hsp_qseq>
      <Hsp_hseq>AFIANAVIHGLKELKEQHN--IIHRDVKPTNILCSANQGTVKLCDFGVSGNLVAS--LAKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYPPETYDNIFSQLSAIVDGPPPRLPSDKFSSDAQDFVSLCLQKIPERRPT</Hsp_hseq>
      <Hsp_midline>A + N  +     +K  H+  ++HRD+K  NI  + N  ++KL DFG++  L  +  LA+T IG   Y++PE       +   Y  +SDIWSLG  + E+    +P+   +  ++  +   I  G    L S ++S D +  ++  L+  P  RP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>5.51213e-11</Hsp_evalue>
      <Hsp_query-from>2</Hsp_query-from>
      <Hsp_query-to>301</Hsp_query-to>
      <Hsp_hit-from>99</Hsp_hit-from>
      <Hsp_hit-to>198</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>53</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>101</Hsp_align-len>
      <Hsp_qseq>VFFPHAQVLNWFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCP-YNNKSDIWSLGCVLYEL</Hsp_qseq>
      <Hsp_hseq>ILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNL-LFSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAEL</Hsp_hseq>
      <Hsp_midline>+ F  A +  W +     V H H   +LHRD+K  N+ L + +  IK+ DFG+AR +    E+  + + T +Y +PE+      Y +  DIWS+G +  EL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>8.72105e-11</Hsp_evalue>
      <Hsp_query-from>32</Hsp_query-from>
      <Hsp_query-to>364</Hsp_query-to>
      <Hsp_hit-from>146</Hsp_hit-from>
      <Hsp_hit-to>264</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>120</Hsp_align-len>
      <Hsp_qseq>WFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARIL--------TNTMELARTCIGTPYYLSPEIC-ENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQ</Hsp_qseq>
      <Hsp_hseq>FLYQILCGLKYIHSADVIHRDLKPGNILCTLN-GCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIK</Hsp_hseq>
      <Hsp_midline>+  QI   +K+IH   V+HRD+K  NI  T N   +K+ DFG+AR +        +         + T +Y +PE+   N PY+   DIW++GC+L E       F G    H + +I +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YIL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:183937:186369:1 gene:YIL095W transcript:YIL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRK1 description:Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton and reduces endocytic ability of cell through the phosphorylation of the Pan1p-Sla1p-End3p protein complex; PRK1 has a paralog, ARK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001357]</Hit_def>
  <Hit_accession>YIL095W</Hit_accession>
  <Hit_len>810</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>1.58242e-10</Hsp_evalue>
      <Hsp_query-from>14</Hsp_query-from>
      <Hsp_query-to>502</Hsp_query-to>
      <Hsp_hit-from>130</Hsp_hit-from>
      <Hsp_hit-to>299</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>178</Hsp_align-len>
      <Hsp_qseq>HAQVLNWFVQICLAVKHIHDRK--VLHRDIKAQNIFLTNNNSSIKLGDFG----IARILTNTMELART-----CIGTPYYLSPEICE---NCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYK-PLSSRYSYDIRSVLAQMLKTNPRNRPSINTILCKCFLSSRIQ</Hsp_qseq>
      <Hsp_hseq>ESEILEIMSQTVQGITAMHALQPPLIHRDIKIENVLISHD-GLYKVCDFGSVSGVIRPPRNTQEFNYVQHDILTNTTAQYRSPEMIDLYRGLPIDEKSDIWALGVFLYKICYYTTPFEKSG----EAGILHARYQYPSFPQYSDRLKNLIRLMLMEAPSQRPNICQVLEEV---SRLQ</Hsp_hseq>
      <Hsp_midline> +++L    Q    +  +H  +  ++HRDIK +N+ ++++    K+ DFG    + R   NT E            T  Y SPE+ +     P + KSDIW+LG  LY++C    PFE +        I    Y+ P   +YS  +++++  ML   P  RP+I  +L +    SR+Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>2.06898e-10</Hsp_evalue>
      <Hsp_query-from>41</Hsp_query-from>
      <Hsp_query-to>340</Hsp_query-to>
      <Hsp_hit-from>269</Hsp_hit-from>
      <Hsp_hit-to>371</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>104</Hsp_align-len>
      <Hsp_qseq>QICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELART---CIGTPYYLSPEICENCP-YNNKSDIWSLGCVLYELCTLNHPFEGNSLR</Hsp_qseq>
      <Hsp_hseq>QLLDGVSYLHQNWVLHRDLKPANIMVT-IDGCVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELIGLQPIFKGEEAK</Hsp_hseq>
      <Hsp_midline>Q+   V ++H   VLHRD+K  NI +T  +  +K+GD G+AR   N ++   T    + T +Y +PE+      Y    D+WS+GC+  EL  L   F+G   +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YFL029C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:78055:79161:-1 gene:YFL029C transcript:YFL029C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CAK1 description:Cyclin-dependent kinase-activating kinase; required for passage through the cell cycle; phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases [Source:SGD;Acc:S000001865]</Hit_def>
  <Hit_accession>YFL029C</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>2.60853e-10</Hsp_evalue>
      <Hsp_query-from>26</Hsp_query-from>
      <Hsp_query-to>292</Hsp_query-to>
      <Hsp_hit-from>134</Hsp_hit-from>
      <Hsp_hit-to>234</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>101</Hsp_align-len>
      <Hsp_qseq>LNWFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIK----LGDFGIARILTNT-------MELARTCIGTPYYLSPEICENCP-YNNKSDIWSLGCVL</Hsp_qseq>
      <Hsp_hseq>LSFFRQMVEGIAFLHENKIIHRDIKPQNIMLTNNTSTVSPKLYIIDFGISYDMANNSQTSAEPMDSKVTDISTGIYKAPEVLFGVKCYDGGVDVWSLLIII</Hsp_hseq>
      <Hsp_midline>L++F Q+   +  +H+ K++HRDIK QNI LTNN S++     + DFGI+  + N        M+   T I T  Y +PE+      Y+   D+WSL  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YDL025C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:405344:407206:-1 gene:YDL025C transcript:YDL025C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RTK1 description:Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002183]</Hit_def>
  <Hit_accession>YDL025C</Hit_accession>
  <Hit_len>620</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>2.91075e-10</Hsp_evalue>
      <Hsp_query-from>32</Hsp_query-from>
      <Hsp_query-to>493</Hsp_query-to>
      <Hsp_hit-from>410</Hsp_hit-from>
      <Hsp_hit-to>577</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>WFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARIL----TNTMELARTCIGTPYYLSPEICENCPYNNK-SDIWSLGCVLYELCTLNHPFEG-----NSLRHLVMK------ICQGSYKPLS--SRYSYDIRSVLAQMLKTNPRNRPSINTILCKCFLSS</Hsp_qseq>
      <Hsp_hseq>YFKQLCHGVNYLHSMGLAHRDLKLDNCVVT-KDGILKLIDFGSAVVFQYPYEDTIVKSHGIVGSDPYLAPELLKQTSYDPRVADVWSIAIIFYCMVLKRFPWKAPKKSFNSFRLFTEEPEDEDDIVRGPNKILRLLPRHS---RTIIGRMLALEPKQRVLMNDVVKDDWLVS</Hsp_hseq>
      <Hsp_midline>+F Q+C  V ++H   + HRD+K  N  +T  +  +KL DFG A +      +T+  +   +G+  YL+PE+ +   Y+ + +D+WS+  + Y +     P++      NS R    +      I +G  K L    R+S   R+++ +ML   P+ R  +N ++   +L S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>3.58609e-10</Hsp_evalue>
      <Hsp_query-from>38</Hsp_query-from>
      <Hsp_query-to>373</Hsp_query-to>
      <Hsp_hit-from>120</Hsp_hit-from>
      <Hsp_hit-to>247</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>131</Hsp_align-len>
      <Hsp_qseq>VQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARIL--------------TNTMELARTC---IGTPYYLSPEIC--ENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSY</Hsp_qseq>
      <Hsp_hseq>AQLIDALEFIHSHGIIHRDLKPENVLL-DRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQCGYG--SDIWALGCMIYQFVQGQPPFRGENELKTFEKIVALDY</Hsp_hseq>
      <Hsp_midline> Q+  A++ IH   ++HRD+K +N+ L + +  + + DFG A  +              +N  +  + C   +GT  Y+SPE+     C Y   SDIW+LGC++Y+      PF G +      KI    Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>3.70845e-10</Hsp_evalue>
      <Hsp_query-from>38</Hsp_query-from>
      <Hsp_query-to>382</Hsp_query-to>
      <Hsp_hit-from>171</Hsp_hit-from>
      <Hsp_hit-to>293</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>127</Hsp_align-len>
      <Hsp_qseq>VQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIA--------RILTNTMELART-CIGTPYYLSPEICE-NCPYNNKS--DIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYKPL</Hsp_qseq>
      <Hsp_hseq>LDVVSGLEYLHSQGITHRDIKPSNLLISSNG-TVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPFNANSGLELFDSIIN---KPL</Hsp_hseq>
      <Hsp_midline>+ +   ++++H + + HRDIK  N+ +++N  ++K+ DFG+A         I ++  +L ++  +GTP + +PE+C     Y+  S  DIWSLG  +Y L     PF  NS   L   I     KPL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>5.10623e-10</Hsp_evalue>
      <Hsp_query-from>38</Hsp_query-from>
      <Hsp_query-to>304</Hsp_query-to>
      <Hsp_hit-from>560</Hsp_hit-from>
      <Hsp_hit-to>647</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>90</Hsp_align-len>
      <Hsp_qseq>VQICLAVKHIHDR-KVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCPYNNKSDIWSLGCVLYELC</Hsp_qseq>
      <Hsp_hseq>VELSLALRFIHDSCHIVHLDLKPANVMITFE-GNLKLGDFGMATHLP-LEDKSFENEGDREYIAPEIISDCTYDYKADIFSLGLMIVEIA</Hsp_hseq>
      <Hsp_midline>V++ LA++ IHD   ++H D+K  N+ +T    ++KLGDFG+A  L    + +    G   Y++PEI  +C Y+ K+DI+SLG ++ E+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>7.99879e-10</Hsp_evalue>
      <Hsp_query-from>11</Hsp_query-from>
      <Hsp_query-to>364</Hsp_query-to>
      <Hsp_hit-from>146</Hsp_hit-from>
      <Hsp_hit-to>263</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>119</Hsp_align-len>
      <Hsp_qseq>PHAQVLNWFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENC-PYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQ</Hsp_qseq>
      <Hsp_hseq>PTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGIAKVCDFGSAQRLDDNTEL-KTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPLFKGDSANSQLEEIAK</Hsp_hseq>
      <Hsp_midline>P   +  +  QI  A+  +H   + H D+K  NI +  ++   K+ DFG A+ L +  EL +T   + +Y +PE+  N   Y  + DIWSLGC++ E+      F+G+S    + +I +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>1.00689e-09</Hsp_evalue>
      <Hsp_query-from>14</Hsp_query-from>
      <Hsp_query-to>364</Hsp_query-to>
      <Hsp_hit-from>129</Hsp_hit-from>
      <Hsp_hit-to>247</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>122</Hsp_align-len>
      <Hsp_qseq>HAQVLNWFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILT----NTMELARTCIGTPYYLSPEICENCP-YNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQ</Hsp_qseq>
      <Hsp_hseq>HYQSFTY--QILCGLKYIHSADVLHRDLKPGNL-LVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQ</Hsp_hseq>
      <Hsp_midline>H Q   +  QI   +K+IH   VLHRD+K  N+ L N +  +K+ DFG+AR  +       +     + T +Y +PEI  +   Y    D+WS GC+L E       F+G    + + +I Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>71</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>1.40207e-09</Hsp_evalue>
      <Hsp_query-from>41</Hsp_query-from>
      <Hsp_query-to>322</Hsp_query-to>
      <Hsp_hit-from>1141</Hsp_hit-from>
      <Hsp_hit-to>1252</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>113</Hsp_align-len>
      <Hsp_qseq>QICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARIL----TNTMELA------------RTCIGTPYYLSPEICENCPYNNK---SDIWSLGCVLYELCTLNHPF</Hsp_qseq>
      <Hsp_hseq>ELLEGLAYLHQSGVVHRDIKPENILL-DFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPW</Hsp_hseq>
      <Hsp_midline>++   + ++H   V+HRDIK +NI L + N  IK  DFG AR +    T T+  A               +GTP Y++PE         K    D+W+LGCV+ E+ T   P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>72</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>1.4312e-09</Hsp_evalue>
      <Hsp_query-from>11</Hsp_query-from>
      <Hsp_query-to>334</Hsp_query-to>
      <Hsp_hit-from>137</Hsp_hit-from>
      <Hsp_hit-to>244</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>110</Hsp_align-len>
      <Hsp_qseq>PHAQVLNWFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILT-NTMELARTCIGTPYYLSPEICENCP-YNNKSDIWSLGCVLYELCTLNHPFEGNS</Hsp_qseq>
      <Hsp_hseq>PLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSISYIC--SRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQE</Hsp_hseq>
      <Hsp_midline>P   +  +  QI   + ++H   V HRDIK  N+ +      +K+ DFG A+ L  N   ++  C  + +Y +PE+   C  Y  + DIW LGCV+ E+      F+G  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>73</Hit_num>
  <Hit_id>YDL028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:400997:403291:-1 gene:YDL028C transcript:YDL028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MPS1 description:Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]</Hit_def>
  <Hit_accession>YDL028C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>1.8533e-09</Hsp_evalue>
      <Hsp_query-from>41</Hsp_query-from>
      <Hsp_query-to>487</Hsp_query-to>
      <Hsp_hit-from>546</Hsp_hit-from>
      <Hsp_hit-to>716</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>173</Hsp_align-len>
      <Hsp_qseq>QICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARIL-TNTMELAR-TCIGTPYYLSPEI---------CENCPYNNK------SDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYK---PLSSRYSYDIRSVLAQMLKT----NPRNRPSINTILCKCFL</Hsp_qseq>
      <Hsp_hseq>EMLLCIKVVHDAGIVHSDLKPANFVLVK--GILKIIDFGIANAVPEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYGKPPYGSFQGQNRLLAIMNPDVKIPFPEHTSNNEKIPKSAIELMKACLYRNPDKRWTVDKVLSSTFL</Hsp_hseq>
      <Hsp_midline>++ L +K +HD  ++H D+K  N  L      +K+ DFGIA  +  +T+ + R T IGTP Y++PE           EN    NK      SD+WS GC++Y++     P+     ++ ++ I     K   P  +  +  I     +++K     NP  R +++ +L   FL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>74</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>2.06333e-09</Hsp_evalue>
      <Hsp_query-from>32</Hsp_query-from>
      <Hsp_query-to>334</Hsp_query-to>
      <Hsp_hit-from>143</Hsp_hit-from>
      <Hsp_hit-to>244</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>103</Hsp_align-len>
      <Hsp_qseq>WFVQICLAVKHIHD-RKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENCP-YNNKSDIWSLGCVLYELCTLNHPFEGNS</Hsp_qseq>
      <Hsp_hseq>YMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPT-EPNVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGES</Hsp_hseq>
      <Hsp_midline>+  Q+  ++ ++H    V HRDIK QN+ +     S+KL DFG A+ L  T E   + I + YY +PE+      Y N+ DIWS GCV+ EL      F G S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>75</Hit_num>
  <Hit_id>YOR061W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:441534:442553:1 gene:YOR061W transcript:YOR061W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA2 description:Alpha&apos; catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000005587]</Hit_def>
  <Hit_accession>YOR061W</Hit_accession>
  <Hit_len>339</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>2.77508e-09</Hsp_evalue>
      <Hsp_query-from>8</Hsp_query-from>
      <Hsp_query-to>361</Hsp_query-to>
      <Hsp_hit-from>139</Hsp_hit-from>
      <Hsp_hit-to>257</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>120</Hsp_align-len>
      <Hsp_qseq>FPHAQVLNWFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENC-PYNNKSDIWSLGCVLYELCTLNHP-FEGNSLRHLVMKIC</Hsp_qseq>
      <Hsp_hseq>FKLPDIQYYFTQLLIALDYCHSMGIMHRDVKPQNVMIDPTERKLRLIDWGLAEFYHPGVDY-NVRVASRYHKGPELLVNLNQYDYSLDLWSVGCMLAAIVFKKEPFFKGSSNPDQLVKIA</Hsp_hseq>
      <Hsp_midline>F    +  +F Q+ +A+ + H   ++HRD+K QN+ +      ++L D+G+A      ++     + + Y+  PE+  N   Y+   D+WS+GC+L  +     P F+G+S    ++KI </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>76</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>3.42792e-09</Hsp_evalue>
      <Hsp_query-from>20</Hsp_query-from>
      <Hsp_query-to>367</Hsp_query-to>
      <Hsp_hit-from>171</Hsp_hit-from>
      <Hsp_hit-to>292</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>129</Hsp_align-len>
      <Hsp_qseq>QVLNWFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARIL------------TNTMELARTCIGTPYYLSPE-ICENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQG</Hsp_qseq>
      <Hsp_hseq>DIKNMMLQILEGLNYIHCAKFMHRDIKTANI-LIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEF------FEKKPILQGKTDIDQG</Hsp_hseq>
      <Hsp_midline> + N  +QI   + +IH  K +HRDIK  NI L ++N  +KL DFG+AR+               +     + + T +Y +PE +  +  Y    DIW +GCV  E       FE   +      I QG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>77</Hit_num>
  <Hit_id>YDL214C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:74446:76545:-1 gene:YDL214C transcript:YDL214C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR2 description:Serine/threonine protein kinase; inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance; PRR2 has a paralog, NPR1, that arose from the whole genome duplication [Source:SGD;Acc:S000002373]</Hit_def>
  <Hit_accession>YDL214C</Hit_accession>
  <Hit_len>699</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.5362</Hsp_bit-score>
      <Hsp_score>140</Hsp_score>
      <Hsp_evalue>4.53768e-09</Hsp_evalue>
      <Hsp_query-from>35</Hsp_query-from>
      <Hsp_query-to>403</Hsp_query-to>
      <Hsp_hit-from>465</Hsp_hit-from>
      <Hsp_hit-to>596</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>133</Hsp_align-len>
      <Hsp_qseq>FVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARI----LTNTMELARTCIGTPYYLSPEICENCPYNNKS-DIWSLGCVLYELCTLNHPFEGNSLRHLVMK-ICQG----SYKPLSSRYSYD</Hsp_qseq>
      <Hsp_hseq>FKQLINGVKYLHDIGLSHRDLKLDNCVVT-RRGILKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFYFNEYDPRALDVWSVGIIFFCMITRRFPWKYPKVKDVQFKAFCSGRGVSSFKDLVTRPATD</Hsp_hseq>
      <Hsp_midline>F Q+   VK++HD  + HRD+K  N  +T     +KL DFG + +    L++ M  A   +G+  YLSPE+     Y+ ++ D+WS+G + + + T   P++   ++ +  K  C G    S+K L +R + D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>78</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>2.82849e-08</Hsp_evalue>
      <Hsp_query-from>17</Hsp_query-from>
      <Hsp_query-to>328</Hsp_query-to>
      <Hsp_hit-from>128</Hsp_hit-from>
      <Hsp_hit-to>235</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>109</Hsp_align-len>
      <Hsp_qseq>AQVLNWFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMEL----ARTCIGTPYYLSPEICENCPYNNKS-DIWSLGCVLYELCTLNHPFEG</Hsp_qseq>
      <Hsp_hseq>AHFQSFIYQILCALKYIHSANVLHCDLKPKNL-LVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFEG</Hsp_hseq>
      <Hsp_midline>A   ++  QI  A+K+IH   VLH D+K +N+ L N++  +K+ +FG++   +   ++     +  I + +Y +PEI  N     K+ DIWS GC+L EL      FEG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>79</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>4.09207e-08</Hsp_evalue>
      <Hsp_query-from>38</Hsp_query-from>
      <Hsp_query-to>322</Hsp_query-to>
      <Hsp_hit-from>1372</Hsp_hit-from>
      <Hsp_hit-to>1500</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>130</Hsp_align-len>
      <Hsp_qseq>VQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIAR-ILTNTMELAR-------------------------------TCIGTPYYLSPEICENCPYNNK---SDIWSLGCVLYELCTLNHPF</Hsp_qseq>
      <Hsp_hseq>LQLLEGLAYLHESGIVHRDVKPENILL-DFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPW</Hsp_hseq>
      <Hsp_midline>+Q+   + ++H+  ++HRD+K +NI L + N  IK  DFG A+ I  N   LA                                  +GTP Y++PE         K    D+WSLGCV+ E+ T   P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>80</Hit_num>
  <Hit_id>YDL079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:312951:314748:-1 gene:YDL079C transcript:YDL079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRK1 description:Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication [Source:SGD;Acc:S000002237]</Hit_def>
  <Hit_accession>YDL079C</Hit_accession>
  <Hit_len>501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>4.82834e-08</Hsp_evalue>
      <Hsp_query-from>8</Hsp_query-from>
      <Hsp_query-to>334</Hsp_query-to>
      <Hsp_hit-from>260</Hsp_hit-from>
      <Hsp_hit-to>369</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>112</Hsp_align-len>
      <Hsp_qseq>FPHAQVLNWFVQICLAVKHIHDR-KVLHRDIKAQNIFLTNNNSSIKLGDFGIARILT-NTMELARTCIGTPYYLSPEICENCP-YNNKSDIWSLGCVLYELCTLNHPFEGNS</Hsp_qseq>
      <Hsp_hseq>MPRVEIKFYAYQLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYIC--SRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGES</Hsp_hseq>
      <Hsp_midline> P  ++  +  Q+  A+ ++H+  ++ HRDIK QN+ +     S K+ DFG A+ L  +   ++  C  + YY +PE+      Y+N+ D+WS  CV+ EL      F G S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>81</Hit_num>
  <Hit_id>YKL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:347214:349136:-1 gene:YKL048C transcript:YKL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ELM1 description:Serine/threonine protein kinase; regulates the orientation checkpoint, the morphogenesis checkpoint and the metabolic switch from fermentative to oxidative metabolism by phosphorylating the activation loop of Kin4p, Hsl1p and Snf4p respectively; cooperates with Hsl7p in recruiting Hsl1p to the septin ring, a prerequisite for subsequent recruitment, phosphorylation, and degradation of Swe1p; forms part of the bud neck ring; regulates cytokinesis [Source:SGD;Acc:S000001531]</Hit_def>
  <Hit_accession>YKL048C</Hit_accession>
  <Hit_len>640</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>7.26851e-08</Hsp_evalue>
      <Hsp_query-from>53</Hsp_query-from>
      <Hsp_query-to>472</Hsp_query-to>
      <Hsp_hit-from>246</Hsp_hit-from>
      <Hsp_hit-to>403</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>161</Hsp_align-len>
      <Hsp_qseq>AVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELART------------CIGTPYYLSPEIC-------ENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYKPLSSRYSYDIRS--VLAQMLKTNPRNRPSINTIL</Hsp_qseq>
      <Hsp_hseq>GLEYLHSQGCIHRDIKPSNILLDEEEKVAKLSDFGSCIFTPQSLPFSDANFEDCFQRELNKIVGTPAFIAPELCHLGNSKRDFVTDGFKLDIWSLGVTLYCLLYNELPFFGENEFETYHKIIEVS---LSSKINGNTLNDLVIKRLLEKDVTLRISIQDLV</Hsp_hseq>
      <Hsp_midline> ++++H +  +HRDIK  NI L       KL DFG       ++  +               +GTP +++PE+C       +      K DIWSLG  LY L     PF G +      KI + S   LSS+ + +  +  V+ ++L+ +   R SI  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>82</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>2.1979e-07</Hsp_evalue>
      <Hsp_query-from>32</Hsp_query-from>
      <Hsp_query-to>472</Hsp_query-to>
      <Hsp_hit-from>429</Hsp_hit-from>
      <Hsp_hit-to>585</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>161</Hsp_align-len>
      <Hsp_qseq>WFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTME----LARTCIGTPYYLSPEICENCPYNNKS-DIWSLGCV---------LYELCTLNHPFEGNSLRHLVMKICQGSYKPLSSRYSYDIRSVLAQMLKTNPRNRPSINTIL</Hsp_qseq>
      <Hsp_hseq>FFKQLIRGVVYMHEMGVCHRDLKPENLLLT-HDGVLKITDFGNSECFKMAWEKNIHLSGGVCGSSPYIAPEEYIKEEFDPRPVDIWACGVIYMAMRTGRQLWSSAEKDDPFYMNYLKGRKEK---GGYEPIESLKRARCRNVIYSMLDPVPYRRINGKQIL</Hsp_hseq>
      <Hsp_midline>+F Q+   V ++H+  V HRD+K +N+ LT ++  +K+ DFG +       E    L+    G+  Y++PE      ++ +  DIW+ G +         L+     + PF  N L+    K   G Y+P+ S      R+V+  ML   P  R +   IL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>83</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>2.68603e-07</Hsp_evalue>
      <Hsp_query-from>23</Hsp_query-from>
      <Hsp_query-to>301</Hsp_query-to>
      <Hsp_hit-from>473</Hsp_hit-from>
      <Hsp_hit-to>563</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>97</Hsp_align-len>
      <Hsp_qseq>VLNWFVQICLAVKHIHDRKVLHRDIKAQNIFL-TNNNSSIKLGDFGIARILTNTMELARTC---IGTPYYLSPEICENCPYNNKSDIWSLGCVLYEL</Hsp_qseq>
      <Hsp_hseq>IRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPELKIIDFG------SSCEEARTVYTYIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAEL</Hsp_hseq>
      <Hsp_midline>+  +  QI  ++  + + K++H D+K +NI L   +   +K+ DFG      ++ E ART    I + +Y +PEI    PY+   D+WSLGC++ EL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>84</Hit_num>
  <Hit_id>YIL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:287790:288908:-1 gene:YIL035C transcript:YIL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA1 description:Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000001297]</Hit_def>
  <Hit_accession>YIL035C</Hit_accession>
  <Hit_len>372</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>3.8232e-07</Hsp_evalue>
      <Hsp_query-from>32</Hsp_query-from>
      <Hsp_query-to>364</Hsp_query-to>
      <Hsp_hit-from>175</Hsp_hit-from>
      <Hsp_hit-to>286</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>113</Hsp_align-len>
      <Hsp_qseq>WFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTNTMELARTCIGTPYYLSPEICENC-PYNNKSDIWSLGCVLYELCTLNHP-FEGNSLRHLVMKICQ</Hsp_qseq>
      <Hsp_hseq>YMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEY-NVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVK</Hsp_hseq>
      <Hsp_midline>+  ++  A+ + H   ++HRD+K  N+ + + N  ++L D+G+A      ME     + + ++  PE+  +   Y+   D+WS G +L  +     P F G S    ++KI +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>85</Hit_num>
  <Hit_id>YNL183C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:293137:295509:-1 gene:YNL183C transcript:YNL183C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NPR1 description:Protein kinase; stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p; negatively regulates Ldb19p-mediated endocytosis through phosphorylation of Ldb19p, which prevents its association with the plasma membrane; Npr1p activity is negatively regulated via phosphorylation by the TOR complex; NPR1 has a paralog, PRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005127]</Hit_def>
  <Hit_accession>YNL183C</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>5.31072e-07</Hsp_evalue>
      <Hsp_query-from>35</Hsp_query-from>
      <Hsp_query-to>367</Hsp_query-to>
      <Hsp_hit-from>542</Hsp_hit-from>
      <Hsp_hit-to>657</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>118</Hsp_align-len>
      <Hsp_qseq>FVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILT-----NTMELARTCIGTPYYLSPEICENCPYNNKS-DIWSLGCVLYELCTLNHPFEGNSLRHLVMKI-CQG</Hsp_qseq>
      <Hsp_hseq>FKQILTGVQYLHSIGLAHRDLKLDNCVI-NEKGIVKLIDFGAAVVFSYPFSKNLVE-ASGIVGSDPYLAPEVCIFAKYDPRPVDIWSSAIIFACMILKKFPWKIPKLRDNSFKLFCSG</Hsp_hseq>
      <Hsp_midline>F QI   V+++H   + HRD+K  N  + N    +KL DFG A + +     N +E A   +G+  YL+PE+C    Y+ +  DIWS   +   +     P++   LR    K+ C G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>86</Hit_num>
  <Hit_id>YPL236C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:101608:102702:-1 gene:YPL236C transcript:YPL236C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ENV7 description:Vacuolar membrane protein kinase; negatively regulates membrane fusion; associates with vacuolar membrane through palmitoylation of one or more cysteines in consensus sequence; vacuolar membrane association is essential to its kinase activity; mutant shows defect in CPY processing; ortholog of human serine/threonine kinase 16 (STK16) [Source:SGD;Acc:S000006157]</Hit_def>
  <Hit_accession>YPL236C</Hit_accession>
  <Hit_len>364</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>9.17733e-07</Hsp_evalue>
      <Hsp_query-from>86</Hsp_query-from>
      <Hsp_query-to>457</Hsp_query-to>
      <Hsp_hit-from>213</Hsp_hit-from>
      <Hsp_hit-to>351</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>HRDIKAQNIFLTNNNSSIKLGDFGIARILTNTME-----------LARTCIGTPYYLSPEICE---NCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRH---LVMKICQGSYK-PLSSRYSYDIRSVLAQMLKTNPRNRPS</Hsp_qseq>
      <Hsp_hseq>HRDITPSNILFSSDGLPV-IGDLGSCSQADITIENRHQLSELQEWVNDNC--TLPYTPPELLNLKLNQVLSSKVDIWSLGCTFYTLMFGISPFEREEQIHGASLTYAINTGKYSFPRNSRFSEGLLSVIKKCIQVDPIQRPT</Hsp_hseq>
      <Hsp_midline>HRDI   NI  +++   + +GD G       T+E           +   C  T  Y  PE+     N   ++K DIWSLGC  Y L     PFE     H   L   I  G Y  P +SR+S  + SV+ + ++ +P  RP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>87</Hit_num>
  <Hit_id>YHR079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:258244:261591:-1 gene:YHR079C transcript:YHR079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IRE1 description:Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; role in homeostatic adaptation to ER stress; Kar2p binds inactive Ire1p and releases from it upon ER stress [Source:SGD;Acc:S000001121]</Hit_def>
  <Hit_accession>YHR079C</Hit_accession>
  <Hit_len>1115</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>1.44606e-06</Hsp_evalue>
      <Hsp_query-from>41</Hsp_query-from>
      <Hsp_query-to>472</Hsp_query-to>
      <Hsp_hit-from>780</Hsp_hit-from>
      <Hsp_hit-to>975</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>58</Hsp_gaps>
      <Hsp_align-len>199</Hsp_align-len>
      <Hsp_qseq>QICLAVKHIHDRKVLHRDIKAQNIFLTNN------------NSSIKLGDFGIARILTNTMELARTCI----GTPYYLSPEICENC--------------------------PYNNKS-----DIWSLGCVLYELCTLN-HPFEGNSLRHLVMKICQGSYKPLSSRYSYDIRSVLA-------QMLKTNPRNRPSINTIL</Hsp_qseq>
      <Hsp_hseq>QIASGVAHLHSLKIIHRDLKPQNILVSTSSRFTADQQTGAENLRILISDFGLCKKLDSGQSSFRTNLNNPSGTSGWRAPELLEESNNLQCQVETEHSSSRHTVVSSDSFYDPFTKRRLTRSIDIFSMGCVFYYILSKGKHPFGDKYSRE--SNIIRGIFSLDEMKCLHD-RSLIAEATDLISQMIDHDPLKRPTAMKVL</Hsp_hseq>
      <Hsp_midline>QI   V H+H  K++HRD+K QNI ++ +            N  I + DFG+ + L +     RT +    GT  + +PE+ E                            P+  +      DI+S+GCV Y + +   HPF     R     I +G +     +  +D RS++A       QM+  +P  RP+   +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>88</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>1.98914e-06</Hsp_evalue>
      <Hsp_query-from>32</Hsp_query-from>
      <Hsp_query-to>451</Hsp_query-to>
      <Hsp_hit-from>429</Hsp_hit-from>
      <Hsp_hit-to>586</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>159</Hsp_align-len>
      <Hsp_qseq>WFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIARILTN----TMELA--------------RTCIGTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYK-PLSSRYSYDIRSVLAQMLKTNPRNR</Hsp_qseq>
      <Hsp_hseq>YASEVVAALEYLHLLGFIYRDLKPENILL-HQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKFPHDKEVSKNCKDLIKKLLNKNEAKR</Hsp_hseq>
      <Hsp_midline>+  ++  A++++H    ++RD+K +NI L + +  + L DF ++   T     TM+ +               + +GT  YL+PE+     +    D W+LG ++YE+     PF+G++       I     K P     S + + ++ ++L  N   R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>89</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>9.17267e-06</Hsp_evalue>
      <Hsp_query-from>32</Hsp_query-from>
      <Hsp_query-to>451</Hsp_query-to>
      <Hsp_hit-from>601</Hsp_hit-from>
      <Hsp_hit-to>761</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>162</Hsp_align-len>
      <Hsp_qseq>WFVQICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDFGIA------------RILTNTMELARTC---------IGTPYYLSPEICENCPYNNKSDIWSLGCVLYELCTLNHPFEGNSLRHLVMKICQGSYK-PLSSRYSYDIRSVLAQMLKTNPRNR</Hsp_qseq>
      <Hsp_hseq>YASEVTAALEYLHLLGFIYRDLKPENILL-HQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKNEVSFPNNNEISRTCKDLIKKLLTKNESKR</Hsp_hseq>
      <Hsp_midline>+  ++  A++++H    ++RD+K +NI L + +  I L DF ++                +T+   + C         +GT  Y++PE+     +    D W+LG ++YE+     PF+G++       I +     P ++  S   + ++ ++L  N   R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>90</Hit_num>
  <Hit_id>YBR097W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:436951:441315:1 gene:YBR097W transcript:YBR097W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VPS15 description:Serine/threonine protein kinase involved in vacuolar protein sorting; functions as a membrane-associated complex with Vps34p; active form recruits Vps34p to the Golgi membrane; interacts with the GDP-bound form of Gpa1p; myristoylated; a fraction is localized, with Vps34p, to nuclear pores at nucleus-vacuole junctions and may facilitate transcription elongation for genes positioned at the nuclear periphery [Source:SGD;Acc:S000000301]</Hit_def>
  <Hit_accession>YBR097W</Hit_accession>
  <Hit_len>1454</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>9.91363e-06</Hsp_evalue>
      <Hsp_query-from>41</Hsp_query-from>
      <Hsp_query-to>478</Hsp_query-to>
      <Hsp_hit-from>130</Hsp_hit-from>
      <Hsp_hit-to>294</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>QICLAVKHIHDRKVLHRDIKAQNIFLTNNNSSIKLGDF--------------GIARILTNTMELARTCIGTPYYLSPEICENCPYNN-----KSDIWSLGCVLYELCTLNHPFEGNSLRHL--VMKICQGSYKP-----LSSRYSYDIRSVLAQMLKTNPRNRPSINTILCK</Hsp_qseq>
      <Hsp_hseq>QLLNALKDIHNLNIVHGDIKTENILVTSWNWCI-LTDFAAFIKPVYLPEDNPGEFLFYFDTSK-RRTCYLAPERFNSKLYQDGKSNNGRLTKEMDIFSLGCVIAEIFA-----EGRPIFNLSQLFKYKSNSYDVNREFLMEEMNSTDLRNLVLDMIQLDPSKRLSCDELLNK</Hsp_hseq>
      <Hsp_midline>Q+  A+K IH+  ++H DIK +NI +T+ N  I L DF              G      +T +  RTC   P   + ++ ++   NN     + DI+SLGCV+ E+       EG  + +L  + K    SY       +    S D+R+++  M++ +P  R S + +L K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2299148340</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0013289-RA transcript Note:&quot;Protein of unknown function&quot; offset:2 AED:1.00 eAED:1.00 QI:2|-1|0|0|-1|0|1|1|104</Iteration_query-def>
  <Iteration_query-len>315</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>75</Statistics_hsp-len>
      <Statistics_eff-space>72572010</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056147-RA transcript Note:&quot;Similar to WDR49 WD repeat-containing protein 49 (Homo sapiens)&quot; offset:0 AED:0.24 eAED:0.25 QI:0|0.25|0.30|0.46|0.66|0.69|13|1432|418</Iteration_query-def>
  <Iteration_query-len>2689</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YMR116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:499456:500688:-1 gene:YMR116C transcript:YMR116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ASC1 description:G-protein beta subunit and guanine dissociation inhibitor for Gpa2p; ortholog of RACK1 that inhibits translation; core component of the small (40S) ribosomal subunit; required to prevent frameshifting at ribosomes stalled at repeated CGA codons; regulates P-body formation induced by replication stress; represses Gcn4p in the absence of amino acid starvation [Source:SGD;Acc:S000004722]</Hit_def>
  <Hit_accession>YMR116C</Hit_accession>
  <Hit_len>319</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>2.07145e-08</Hsp_evalue>
      <Hsp_query-from>535</Hsp_query-from>
      <Hsp_query-to>912</Hsp_query-to>
      <Hsp_hit-from>103</Hsp_hit-from>
      <Hsp_hit-to>227</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>133</Hsp_align-len>
      <Hsp_qseq>FRVHKG-VKTFCFSKERSLVVTGGMDRTVRLWNPYVPGRPTGVLRGHTSPICYLSIC------EETSRIFSVGSDRNVKVVKLWDLDSGLPTFEFCGAHGESAITCMAFDSSGRSLLATSSYDGEVIVWNLVS</Hsp_qseq>
      <Hsp_hseq>FVGHKSDVMSVDIDKKASMIISGSRDKTIKVWT--IKGQCLATLLGHNDWVSQVRVVPNEKADDDSVTIISAGND---KMVKAWNLNQFQIEADFIG-HNSNINTLTA--SPDGTLIASAGKDGEIMLWNLAA</Hsp_hseq>
      <Hsp_midline>F  HK  V +    K+ S++++G  D+T+++W   + G+    L GH   +  + +       +++  I S G+D   K+VK W+L+      +F G H  +  T  A  S   +L+A++  DGE+++WNL +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YCR084C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:260311:262452:-1 gene:YCR084C transcript:YCR084C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TUP1 description:General repressor of transcription; forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes [Source:SGD;Acc:S000000680]</Hit_def>
  <Hit_accession>YCR084C</Hit_accession>
  <Hit_len>713</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>7.32725e-08</Hsp_evalue>
      <Hsp_query-from>553</Hsp_query-from>
      <Hsp_query-to>1104</Hsp_query-to>
      <Hsp_hit-from>446</Hsp_hit-from>
      <Hsp_hit-to>608</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>185</Hsp_align-len>
      <Hsp_qseq>VKTFCFSKERSLVVTGGMDRTVRLWNPYVPGRP-TGVLRGHTSPICYLSICEETSRIFSVGSDRNVKVVKLWDLDSGLPTFEFCGAHGESAITCMAFDSSGRSLLATSSYDGEVIVWNLVSGHGRQGRPVCCLASALGDSVLLAADQTGHVYAWDVSSMDVIEEHKLLLTAALDCSVRLWSVDGA</Hsp_qseq>
      <Hsp_hseq>IRSVCFSPDGKFLATGAEDRLIRIWD--IENRKIVMILQGHEQDIYSLDYFPSGDKLVSGSGDRTVRI---WDLRTGQCSLTLSIEDG---VTTVAVSPGDGKYIAAGSLDRAVRVWDSETGF---------LVERLD-----SENESGTGHKDSVYSVVFTRDGQSVVSGSLDRSVKLWNLQNA</Hsp_hseq>
      <Hsp_midline>+++ CFS +   + TG  DR +R+W+  +  R    +L+GH   I  L       ++ S   DR V++   WDL +G  +       G   +T +A        +A  S D  V VW+  +G          L   L      + +++G  +   V S+    + + +++ +LD SV+LW++  A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YLR129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:399657:402488:1 gene:YLR129W transcript:YLR129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DIP2 description:Nucleolar protein; specifically associated with the U3 snoRNA, part of the large ribonucleoprotein complex known as the small subunit (SSU) processome, required for 18S rRNA biogenesis, part of the active pre-rRNA processing complex [Source:SGD;Acc:S000004119]</Hit_def>
  <Hit_accession>YLR129W</Hit_accession>
  <Hit_len>943</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>1.26833e-07</Hsp_evalue>
      <Hsp_query-from>751</Hsp_query-from>
      <Hsp_query-to>1098</Hsp_query-to>
      <Hsp_hit-from>102</Hsp_hit-from>
      <Hsp_hit-to>232</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>134</Hsp_align-len>
      <Hsp_qseq>VVKLWDLDSGLPTFEFCGAHGESAITCMAFDSSGRSLLATSSYDGEVIVWNLVSGHG----RQGRPVCCLASALGDSVLLAADQTGHVYAWDVSSMDVIEEH--------------KLLLTAALDCSVRLWSVD</Hsp_qseq>
      <Hsp_hseq>VIKVWDLMSKTVLLNFNGH--KAAITLLQFDGTGTRLISGSK-DSNIIVWDLVGEVGLYKLRSHKDSITGFWCQGEDWLISTSKDGMIKLWDLKTHQCIETHIAHTGECWGLAVKDDLLITTGTDSQVKIWKLD</Hsp_hseq>
      <Hsp_midline>V+K+WDL S      F G   ++AIT + FD +G  L++ S  D  +IVW+LV   G    R  +         G+  L++  + G +  WD+ +   IE H               LL+T   D  V++W +D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YCR072C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:240805:242352:-1 gene:YCR072C transcript:YCR072C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RSA4 description:WD-repeat protein involved in ribosome biogenesis; may interact with ribosomes; required for maturation and efficient intra-nuclear transport or pre-60S ribosomal subunits, localizes to the nucleolus [Source:SGD;Acc:S000000668]</Hit_def>
  <Hit_accession>YCR072C</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>3.66603e-06</Hsp_evalue>
      <Hsp_query-from>490</Hsp_query-from>
      <Hsp_query-to>954</Hsp_query-to>
      <Hsp_hit-from>164</Hsp_hit-from>
      <Hsp_hit-to>318</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>164</Hsp_align-len>
      <Hsp_qseq>GLGAARRRTATDQTVFRVHKG----VKTFCFSKERSLVVTGGMDRTVRLWNPYVPGRPTGVLRGHTSPICYLS-----ICEETSRIFSVGSDRNVKVVKLWDLDSGLPTFEFCGAHGESAITCMAFDSSGRSLLATSSYDGEVIVWNLVSGHGRQGRPVCCLAS</Hsp_qseq>
      <Hsp_hseq>GDNTARIWDCDTQTPMHTLKGHYNWVLCVSWSPDGEVIATGSMDNTIRLWDPKSGQCLGDALRGHSKWITSLSWEPIHLVKPGSKPRLASSSKD-GTIKIWDTVSRVCQYTMSGH--TNSVSCVKW--GGQGLLYSGSHDRTVRVWDINS----QGRCINILKS</Hsp_hseq>
      <Hsp_midline>G   AR      QT     KG    V    +S +  ++ TG MD T+RLW+P         LRGH+  I  LS     + +  S+     S ++   +K+WD  S +  +   G    ++++C+ +   G+ LL + S+D  V VW++ S    QGR +  L S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YBR175W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:582408:583355:1 gene:YBR175W transcript:YBR175W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWD3 description:Essential subunit of the COMPASS (Set1C) complex; COMPASS methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5 [Source:SGD;Acc:S000000379]</Hit_def>
  <Hit_accession>YBR175W</Hit_accession>
  <Hit_len>315</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.595</Hsp_bit-score>
      <Hsp_score>109</Hsp_score>
      <Hsp_evalue>8.95221e-06</Hsp_evalue>
      <Hsp_query-from>505</Hsp_query-from>
      <Hsp_query-to>1119</Hsp_query-to>
      <Hsp_hit-from>42</Hsp_hit-from>
      <Hsp_hit-to>227</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>206</Hsp_align-len>
      <Hsp_qseq>RRRTATDQTVFRVHKGVKTFCFSKERSLVVTGGMDRTVRLWNPYVPGRPTGVLRGHTSPICYLSICEETSRIFSVGSDRNVKVVKLWDLDSGLPTFEFCGAHGESAITCMAFDSSGRSLLATSSYDGEVIVWNLVSGHGRQGRPVCCLASALGDSVLLAADQTGHVYAWDVSSMDVIEEHKLLLTAALDCSVRLWS-VDGAFVGTF</Hsp_qseq>
      <Hsp_hseq>NRRTVSQTLVTSHARPFSELCWSPDGQCIATASDDFSVEIIHLSYGLLHTFI--GHTAPVISLTFNRKGNLLFTSSMDESIKI---WDTLNG-SLMKTISAHSE-AVVSVDVPMNDSSILSSGSYDGLIRIFDAETGH--------CLKTLTYDK-----DWKRENGVVPISQVKFSENARYLLVKSLDGVVKIWDCIGGCVVRTF</Hsp_hseq>
      <Hsp_midline> RRT +   V    +     C+S +   + T   D +V + +       T +  GHT+P+  L+   + + +F+   D ++K+   WD  +G    +   AH E A+  +    +  S+L++ SYDG + +++  +GH        CL +   D      D         +S +   E  + LL  +LD  V++W  + G  V TF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1809279066</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0007399-RA transcript Note:&quot;Similar to Fat3 Protocadherin Fat 3 (Rattus norvegicus)&quot; offset:0 AED:0.25 eAED:0.25 QI:0|0|0|0.25|0.33|0.25|4|0|117</Iteration_query-def>
  <Iteration_query-len>354</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>78</Statistics_hsp-len>
      <Statistics_eff-space>95970680</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056148-RA transcript Note:&quot;Similar to Hectd3 E3 ubiquitin-protein ligase HECTD3 (Mus musculus)&quot; offset:208 AED:0.09 eAED:0.09 QI:208|0.75|0.82|1|0.56|0.47|17|1728|642</Iteration_query-def>
  <Iteration_query-len>3865</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2667743329</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0009098-RA transcript Note:&quot;Similar to Stard13 StAR-related lipid transfer protein 13 (Mus musculus)&quot; offset:476 AED:0.12 eAED:0.12 QI:476|0.23|0.07|0.85|0.23|0.07|14|1557|783</Iteration_query-def>
  <Iteration_query-len>4385</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>102</Statistics_hsp-len>
      <Statistics_eff-space>3045338253</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056149-RA transcript Note:&quot;Similar to yipf6 Protein YIPF6 (Xenopus tropicalis)&quot; offset:0 AED:0.16 eAED:0.16 QI:0|1|0.87|1|0.28|0.25|8|2035|241</Iteration_query-def>
  <Iteration_query-len>2761</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YGR172C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:842845:843591:-1 gene:YGR172C transcript:YGR172C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YIP1 description:Integral membrane protein; required for the biogenesis of ER-derived COPII transport vesicles; interacts with Yif1p and Yos1p; localizes to the Golgi, the ER, and COPII vesicles; human homolog YIPF5 can complement yeast yip1 mutant [Source:SGD;Acc:S000003404]</Hit_def>
  <Hit_accession>YGR172C</Hit_accession>
  <Hit_len>248</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.2098</Hsp_bit-score>
      <Hsp_score>108</Hsp_score>
      <Hsp_evalue>9.41067e-06</Hsp_evalue>
      <Hsp_query-from>211</Hsp_query-from>
      <Hsp_query-to>708</Hsp_query-to>
      <Hsp_hit-from>74</Hsp_hit-from>
      <Hsp_hit-to>246</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>186</Hsp_align-len>
      <Hsp_qseq>MKAVGKKFIHVLYPKK------------SSELLRDWDLWGPLILCVLLAAMLQAKTPVDKASQGPQFAEVFVLVWVGAIVVTLNSQLLGGN-------ISFFQSLCVLGYCVMPLTVSMIVCLITTLATKTLVLTIINCIVVFLSFGWSVFASTAFLAD-SQPPNRKALAVYPIFLFYFVISWIIL</Hsp_qseq>
      <Hsp_hseq>LEEIGINFDHIITKTKMVLIPIRFGSGVPQEILNDSDLAGPLIFFLLFGLFLLMAGKV-------HFGYIYGVALFGTISLHNLSKLMSNNDTSTQTNLQFFNTASILGYCFLPL------CFLSLLGIFHGLNNTTGYVVSVLFVIWSTWTSSGFLNSLLQLQNARLLIAYPLLIFYSVFALMVI</Hsp_hseq>
      <Hsp_midline>++ +G  F H++   K              E+L D DL GPLI  +L    L     V        F  ++ +   G I +   S+L+  N       + FF +  +LGYC +PL      C ++ L     +      +V  L   WS + S+ FL    Q  N + L  YP+ +FY V + +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>1856007607</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056150-RA transcript Note:&quot;Similar to PDCL3 Phosducin-like protein 3 (Pongo abelii)&quot; offset:147 AED:0.19 eAED:0.19 QI:147|0.8|0.83|1|0.2|0.33|6|2346|214</Iteration_query-def>
  <Iteration_query-len>3138</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YOR281C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:846269:847129:-1 gene:YOR281C transcript:YOR281C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PLP2 description:Protein that interacts with the CCT complex to stimulate actin folding; has similarity to phosducins; null mutant lethality is complemented by mouse phosducin-like protein MgcPhLP; CCT is short for chaperonin containing TCP-1; essential gene [Source:SGD;Acc:S000005807]</Hit_def>
  <Hit_accession>YOR281C</Hit_accession>
  <Hit_len>286</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>1.30057e-10</Hsp_evalue>
      <Hsp_query-from>154</Hsp_query-from>
      <Hsp_query-to>642</Hsp_query-to>
      <Hsp_hit-from>12</Hsp_hit-from>
      <Hsp_hit-to>192</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>181</Hsp_align-len>
      <Hsp_qseq>DPNEDTEWNSILRKHGIIXXXXXXXXXXXXXXXXXXSVVKNYDDMTIXXXXXXXXXXXXXXXRVIEMYRQKRLAEWKAQQMKNKFGDVLEISGQDYVHEVTKAGPD------------------IFVVLHLYKQGIPLCALINQHLTALARKFPDTKFLKSISTTCIPNYPDKNLPTIFVY</Hsp_qseq>
      <Hsp_hseq>DESEDSEWNDILRAKGVIPERAPSPTAKLEEALEEAIAKQHENRLEDKDLSDLEELEDDEDEDFLEAYKIKRLNEIRKLQERSKFGEVFHINKPEYNKEVTLASQGKKYEGAQTNDNGEEDDGGVYVFVHLSLQSKLQSRILSHLFQSAACKFREIKFVEIPANRAIENYPESNCPTLIVY</Hsp_hseq>
      <Hsp_midline>D +ED+EWN ILR  G+IP++      + E   ++    ++ + +   +  +LE+  ++EDE  +E Y+ KRL E +  Q ++KFG+V  I+  +Y  EVT A                     ++V +HL  Q      +++    + A KF + KF++  +   I NYP+ N PT+ VY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2132347382</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056152-RA transcript Note:&quot;Similar to FAT1 Protocadherin Fat 1 (Homo sapiens)&quot; offset:0 AED:0.20 eAED:0.20 QI:0|0|0|0.8|0.75|0.8|5|0|1577</Iteration_query-def>
  <Iteration_query-len>4734</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3295543825</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056153-RA transcript Note:&quot;Similar to FAT1 Protocadherin Fat 1 (Homo sapiens)&quot; offset:0 AED:0.64 eAED:0.64 QI:0|0|0|0.5|1|1|14|0|1169</Iteration_query-def>
  <Iteration_query-len>3510</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2411851690</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056154-RA transcript Note:&quot;Similar to mtnr1aa Melatonin receptor type 1A-A (Danio rerio)&quot; offset:0 AED:0.28 eAED:0.28 QI:0|0|0|0.33|1|1|3|0|330</Iteration_query-def>
  <Iteration_query-len>993</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>559136147</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0038166-RA transcript Note:&quot;Similar to Aimp1 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (Mus musculus)&quot; offset:0 AED:0.52 eAED:0.52 QI:0|0.33|0|0.75|1|0.75|4|0|179</Iteration_query-def>
  <Iteration_query-len>540</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YGL105W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:307437:308567:1 gene:YGL105W transcript:YGL105W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ARC1 description:Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases; involved in tRNA delivery, stimulating catalysis, and ensuring localization; also binds quadruplex nucleic acids; protein abundance increases in response to DNA replication stress; methionyl-tRNA synthetase is Mes1p; glutamyl-tRNA synthetase is Gus1p [Source:SGD;Acc:S000003073]</Hit_def>
  <Hit_accession>YGL105W</Hit_accession>
  <Hit_len>376</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>135.576</Hsp_bit-score>
      <Hsp_score>340</Hsp_score>
      <Hsp_evalue>3.32803e-39</Hsp_evalue>
      <Hsp_query-from>64</Hsp_query-from>
      <Hsp_query-to>468</Hsp_query-to>
      <Hsp_hit-from>207</Hsp_hit-from>
      <Hsp_hit-to>345</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>144</Hsp_align-len>
      <Hsp_qseq>SRLDLRVGRIVSAQKHPDADSLYVEQVDVA-EAAARTVVSGLVKHIPLEQMQDRMIVVMCNLKPAKMRGVLSQAMVMCASSSDKLMGGRGPR--------VFSGIGLTWPNSGEPDKELNPKKKIWEQVQPDLLTNGEFVATYK</Hsp_qseq>
      <Hsp_hseq>SAIDFRVGFIQKAIKHPDADSLYVSTIDVGDEEGPRTVCSGLVKHFPLDAMQERYVVVVCNLKPVNMRGIKSTAMVLCGSNDDKVEFVEPPKDSKAGDKVFFEGFG-----DEAPMKQLNPKKKIWEHLQPHFTTNDGLEVIFK</Hsp_hseq>
      <Hsp_midline>S +D RVG I  A KHPDADSLYV  +DV  E   RTV SGLVKH PL+ MQ+R +VV+CNLKP  MRG+ S AMV+C S+ DK+     P+         F G G        P K+LNPKKKIWE +QP   TN      +K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>84</Statistics_hsp-len>
      <Statistics_eff-space>226528032</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056155-RA transcript Note:&quot;Similar to egfl6 Epidermal growth factor-like protein 6 (Xenopus laevis)&quot; offset:73 AED:0.33 eAED:0.33 QI:73|0.5|0.6|0.8|1|1|5|0|297</Iteration_query-def>
  <Iteration_query-len>967</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>538255544</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056157-RA transcript Note:&quot;Similar to GSTCD Glutathione S-transferase C-terminal domain-containing protein (Bos taurus)&quot; offset:31 AED:0.28 eAED:0.29 QI:31|0.71|0.5|0.87|1|1|8|0|516</Iteration_query-def>
  <Iteration_query-len>1582</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>993157811</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056158-RA transcript Note:&quot;Similar to TMSB10 Thymosin beta-10 (Bos taurus)&quot; offset:0 AED:0.63 eAED:0.63 QI:0|0.5|0.66|0.66|1|1|3|428|249</Iteration_query-def>
  <Iteration_query-len>1178</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>92</Statistics_hsp-len>
      <Statistics_eff-space>692060100</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056159-RA transcript Note:&quot;Similar to AFF3 AF4/FMR2 family member 3 (Homo sapiens)&quot; offset:2 AED:0.27 eAED:0.27 QI:2|0.07|0.14|0.14|0.92|0.85|14|2693|1210</Iteration_query-def>
  <Iteration_query-len>6328</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>105</Statistics_hsp-len>
      <Statistics_eff-space>4451018268</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056160-RA transcript Note:&quot;Similar to Cyb5d2 Neuferricin (Rattus norvegicus)&quot; offset:488 AED:0.33 eAED:0.33 QI:488|0.33|0.25|0.75|0.33|0.5|4|0|215</Iteration_query-def>
  <Iteration_query-len>1136</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YPL170W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:228314:228772:1 gene:YPL170W transcript:YPL170W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DAP1 description:Heme-binding protein; involved in regulation of cytochrome P450 protein Erg11p; damage response protein, related to mammalian membrane progesterone receptors; mutations lead to defects in telomeres, mitochondria, and sterol synthesis [Source:SGD;Acc:S000006091]</Hit_def>
  <Hit_accession>YPL170W</Hit_accession>
  <Hit_len>152</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.9802</Hsp_bit-score>
      <Hsp_score>110</Hsp_score>
      <Hsp_evalue>4.79022e-07</Hsp_evalue>
      <Hsp_query-from>591</Hsp_query-from>
      <Hsp_query-to>956</Hsp_query-to>
      <Hsp_hit-from>37</Hsp_hit-from>
      <Hsp_hit-to>145</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>123</Hsp_align-len>
      <Hsp_qseq>QQLLPAHFFPSPSSGQQRLLTLSELGRYDGQEGSPGLYLAVLGQVFDVSKGAKHYGPGASYQALAG-DLTAGHVMNVPPLESGDFSDAGLVDDVSGLSPAQMLGLHDWLSFYQRDYAYVGKLV</Hsp_qseq>
      <Hsp_hseq>EPVVAGNFFPR---------TLSKFNGHDDEK----IFIAIRGKVYDCTRGRQFYGPSGPYTNFAGHDASRGLALNSFDLDVIKDWDQ-PIDPLDDLTKEQIDALDEWQEHFENKYPCIGTLI</Hsp_hseq>
      <Hsp_midline>+ ++  +FFP          TLS+   +D ++    +++A+ G+V+D ++G + YGP   Y   AG D + G  +N   L+     D   +D +  L+  Q+  L +W   ++  Y  +G L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>663965029</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056161-RA transcript Note:&quot;Similar to PIH1D3 Protein PIH1D3 (Homo sapiens)&quot; offset:126 AED:0.31 eAED:0.31 QI:126|1|1|1|1|1|6|1045|195</Iteration_query-def>
  <Iteration_query-len>1759</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1122949897</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

