<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0052694-RA transcript Note:&quot;Similar to HERC5 E3 ISG15--protein ligase HERC5 (Homo sapiens)&quot; offset:154 AED:0.01 eAED:0.01 QI:154|1|1|1|0|0.2|5|1374|209</BlastOutput_query-def>
  <BlastOutput_query-len>2158</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052694-RA transcript Note:&quot;Similar to HERC5 E3 ISG15--protein ligase HERC5 (Homo sapiens)&quot; offset:154 AED:0.01 eAED:0.01 QI:154|1|1|1|0|0.2|5|1374|209</Iteration_query-def>
  <Iteration_query-len>2158</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YGL097W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:321782:323230:1 gene:YGL097W transcript:YGL097W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SRM1 description:Nucleotide exchange factor for Gsp1p; localizes to the nucleus, required for nucleocytoplasmic trafficking of macromolecules; suppressor of the pheromone response pathway; potentially phosphorylated by Cdc28p; human homolog of the RAN GEF, RCC1, can complement a temperature sensitive point mutant [Source:SGD;Acc:S000003065]</Hit_def>
  <Hit_accession>YGL097W</Hit_accession>
  <Hit_len>482</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>2.74065e-09</Hsp_evalue>
      <Hsp_query-from>251</Hsp_query-from>
      <Hsp_query-to>781</Hsp_query-to>
      <Hsp_hit-from>185</Hsp_hit-from>
      <Hsp_hit-to>355</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>182</Hsp_align-len>
      <Hsp_qseq>RLFAWG---CGEFGQHGHGQGANVESHQGW-LPQFSTEHLGAVHLLACGATHTLVVTETNRIFSWGHGHSGQLGCGDSSIRGEPVEVQLAPSGCRGDMEVAGVACGSRHSFVWTRSGRCFSFGNNFYAQLGYDFQKRDYKANQCVPYPLNMSLMGRRV-EWVSCGERHSLFLFEDRRIAACG</Hsp_qseq>
      <Hsp_hseq>EVYAWGTFRCNE-GILGFYQDKIKIQKTPWKVPTFSKYNIVQ---LAPGKDHILFLDEEGMVFAWGNGQQNQLGRKVME-RFRLKTLDPRPFGLR---HVKYIASGENHCFALTKDNKLVSWGLNQFGQCGV---SEDVEDGALVTKPKRLALPDNVVIRSIAAGEHHSLILSQDGDLYSCG</Hsp_hseq>
      <Hsp_midline> ++AWG   C E G  G  Q         W +P FS  ++     LA G  H L + E   +F+WG+G   QLG      R     +   P G R    V  +A G  H F  T+  +  S+G N + Q G      D +    V  P  ++L    V   ++ GE HSL L +D  + +CG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1414345274</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052695-RA transcript Note:&quot;Similar to ADGRV1 Adhesion G-protein coupled receptor V1 (Homo sapiens)&quot; offset:0 AED:0.42 eAED:0.42 QI:0|0.91|0.84|1|0.25|0.30|13|1062|713</Iteration_query-def>
  <Iteration_query-len>3204</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2181936856</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052696-RA transcript Note:&quot;Similar to ADGRV1 Adhesion G-protein coupled receptor V1 (Homo sapiens)&quot; offset:0 AED:0.43 eAED:0.43 QI:0|0.03|0.03|0.88|0.80|0.85|27|0|1739</Iteration_query-def>
  <Iteration_query-len>5220</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3657495079</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052697-RA transcript Note:&quot;Similar to CDO1 Cysteine dioxygenase type 1 (Pongo abelii)&quot; offset:440 AED:0.02 eAED:0.02 QI:440|1|1|1|0.66|0.5|4|2467|149</Iteration_query-def>
  <Iteration_query-len>3357</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2296894273</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0007253-RA transcript Note:&quot;Similar to RFESD Rieske domain-containing protein (Homo sapiens)&quot; offset:200 AED:0.37 eAED:0.37 QI:200|0.7|0.63|1|0.1|0.18|11|0|663</Iteration_query-def>
  <Iteration_query-len>2192</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1439357811</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052699-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.23 eAED:0.23 QI:0|0.75|0.8|0.8|0.25|0.2|5|0|92</Iteration_query-def>
  <Iteration_query-len>279</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>64</Statistics_hsp-len>
      <Statistics_eff-space>72258343</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0007256-RA transcript Note:&quot;Similar to Cilp Cartilage intermediate layer protein 1 (Mus musculus)&quot; offset:0 AED:0.16 eAED:0.21 QI:0|0|0|0.75|0.71|0.5|8|0|989</Iteration_query-def>
  <Iteration_query-len>2970</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>2014254297</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052701-RA transcript Note:&quot;Similar to Ccdc112 Coiled-coil domain-containing protein 112 (Mus musculus)&quot; offset:0 AED:0.29 eAED:0.32 QI:0|0.6|0.66|1|0|0|6|1462|213</Iteration_query-def>
  <Iteration_query-len>2104</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1379682535</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0002712-RA transcript Note:&quot;Similar to Ankrd34c Ankyrin repeat domain-containing protein 34C (Mus musculus)&quot; offset:0 AED:0.22 eAED:0.23 QI:0|-1|0|1|-1|1|1|0|530</Iteration_query-def>
  <Iteration_query-len>1593</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>1002332479</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052698-RA transcript Note:&quot;Similar to ANPEP Aminopeptidase Ey (Gallus gallus)&quot; offset:0 AED:0.51 eAED:0.61 QI:0|0|0|1|0|0|3|0|132</Iteration_query-def>
  <Iteration_query-len>399</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>80</Statistics_hsp-len>
      <Statistics_eff-space>126461551</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052702-RA transcript Note:&quot;Similar to Msh3 DNA mismatch repair protein Msh3 (Mus musculus)&quot; offset:103 AED:0.36 eAED:0.36 QI:103|0.72|0.83|0.91|0.09|0.16|12|0|615</Iteration_query-def>
  <Iteration_query-len>1951</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YCR092C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:276764:279820:-1 gene:YCR092C transcript:YCR092C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MSH3 description:Mismatch repair protein; forms dimers with Msh2p that mediate repair of insertion or deletion mutations and removal of nonhomologous DNA ends, contains a PCNA (Pol30p) binding motif required for genome stability [Source:SGD;Acc:S000000688]</Hit_def>
  <Hit_accession>YCR092C</Hit_accession>
  <Hit_len>1018</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>124.79</Hsp_bit-score>
      <Hsp_score>312</Hsp_score>
      <Hsp_evalue>5.30819e-30</Hsp_evalue>
      <Hsp_query-from>716</Hsp_query-from>
      <Hsp_query-to>1774</Hsp_query-to>
      <Hsp_hit-from>133</Hsp_hit-from>
      <Hsp_hit-to>519</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>113</Hsp_identity>
      <Hsp_positive>187</Hsp_positive>
      <Hsp_gaps>104</Hsp_gaps>
      <Hsp_align-len>422</Hsp_align-len>
      <Hsp_qseq>TPLEQQYLDIKEQHGGTLLLVECGYKHRFFGEDAEIAAKELNI-----------TCHQDHN---FMTASIPTHRLFIHVRRLVAKGYKVGVVKQTETTALKA--AGENKSALFSRKLTALYTKST--------LIGEDILVN----------------------AVQPSTGELLFDCFEDGK-ARLELESRVLSLQPVELLI-----PAALSDETERSLCSLTANSSQGXXXXXXXXXXXXLFEHSRAFQAVSRFFGAESLQSNCNHDEQKLSHVLAMEKPIIACLAVLIHYLTEFGLERVLYLSSTAIACTPYASIRQ--------------TNGKVKGSLLWAMDRTCTPFGRRMFRNWLGRPLISISDINARLDCVSEILASE---HMVLSRAKELLWKLPDLERGLTSIYHRKCSTKE</Hsp_qseq>
      <Hsp_hseq>TPLDKQVKDLKMHHRDKVLVIRVGYKYKCFAEDAVTVSRILHIKLVPGKLTIDESNPQDCNHRQFAYCSFPDVRLNVHLERLVHHNLKVAVVEQAETSAIKKHDPGASKSSVFERKISNVFTKATFGVNSTFVLRGKRILGDTNSIWALSRDVHQGKVAKYSLISVNLNNGEVVYDEFEEPNLADEKLQIRIKYLQPIEVLVNTDDLPLHVAKFFKDISCPLI---------------------HKQEY----------DLEDHVVQAIKVMNEKIQLSPSLIRLVSKLYSHMVEYNNEQVMLIPSI---YSPFASKIHMLLDPNSLQSLDIFTHDGGKGSLFWLLDHTRTSFGLRMLREWILKPLVDVHQIEERLDAI-ECITSEINNSIFFESLNQMLNHTPDLLRTLNRIMYGTTSRKE</Hsp_hseq>
      <Hsp_midline>TPL++Q  D+K  H   +L++  GYK++ F EDA   ++ L+I           +  QD N   F   S P  RL +H+ RLV    KV VV+Q ET+A+K    G +KS++F RK++ ++TK+T        L G+ IL +                      +V  + GE+++D FE+   A  +L+ R+  LQP+E+L+     P  ++   +   C L                      H + +           L+ +     + ++  + +   +I  ++ L  ++ E+  E+V+ + S     +P+AS                 T+   KGSL W +D T T FG RM R W+ +PL+ +  I  RLD + E + SE    +      ++L   PDL R L  I +   S KE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YDR097C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:640109:643837:-1 gene:YDR097C transcript:YDR097C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MSH6 description:Protein required for mismatch repair in mitosis and meiosis; forms a complex with Msh2p to repair both single-base &amp; insertion-deletion mispairs; also involved in interstrand cross-link repair; potentially phosphorylated by Cdc28p [Source:SGD;Acc:S000002504]</Hit_def>
  <Hit_accession>YDR097C</Hit_accession>
  <Hit_len>1242</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>5.41417e-13</Hsp_evalue>
      <Hsp_query-from>1520</Hsp_query-from>
      <Hsp_query-to>1810</Hsp_query-to>
      <Hsp_hit-from>632</Hsp_hit-from>
      <Hsp_hit-to>727</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>98</Hsp_align-len>
      <Hsp_qseq>NGKVKGSLLWAMDRTCTPFGRRMFRNWLGRPLISISDINARLDCVSEILASEHMVLSRAKELLW-KLPDLERGLTSIYHRKCSTKEFSLIASSLERLC</Hsp_qseq>
      <Hsp_hseq>DGSDKGTLFKLFNRAITPMGKRMMKKWLMHPLLRKNDIESRLDSVDSLL--QDITLREQLEITFSKLPDLERMLARIHSRTIKVKDFEKVITAFETII</Hsp_hseq>
      <Hsp_midline>+G  KG+L    +R  TP G+RM + WL  PL+  +DI +RLD V  +L  + + L    E+ + KLPDLER L  I+ R    K+F  + ++ E + </Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>1.74862e-07</Hsp_evalue>
      <Hsp_query-from>665</Hsp_query-from>
      <Hsp_query-to>1063</Hsp_query-to>
      <Hsp_hit-from>289</Hsp_hit-from>
      <Hsp_hit-to>429</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>142</Hsp_align-len>
      <Hsp_qseq>RPKAVDSTLNKRTKTI-------YTPLEQQYLDIKEQHGGTLLLVECGYKHRFFGEDAEIAAK--ELNITCHQDHNFMTASIPTHRLFIHVRRLVAKGYKVGVVKQTETTALKAAGENKSALFSRKLTALYTKSTLIGEDIL</Hsp_qseq>
      <Hsp_hseq>RPKS-DPEYDPRTLYIPSSAWNKFTPFEKQYWEIKSKMWDCIVFFKKGKFFELYEKDALLANALFDLKIAGGGRANMQLAGIPEMSFEYWAAQFIQMGYKVAKVDQRESMLAKEMREGSKGIVKRELQCILTSGTLTDGDML</Hsp_hseq>
      <Hsp_midline>RPK+ D   + RT  I       +TP E+QY +IK +    ++  + G     + +DA +A    +L I      N   A IP         + +  GYKV  V Q E+   K   E    +  R+L  + T  TL   D+L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YHR120W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:349574:352453:1 gene:YHR120W transcript:YHR120W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MSH1 description:DNA-binding protein of the mitochondria; involved in repair of mitochondrial DNA; has ATPase activity and binds to DNA mismatches; has homology to E. coli MutS; transcription is induced during meiosis [Source:SGD;Acc:S000001162]</Hit_def>
  <Hit_accession>YHR120W</Hit_accession>
  <Hit_len>959</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>1.27637e-07</Hsp_evalue>
      <Hsp_query-from>875</Hsp_query-from>
      <Hsp_query-to>1801</Hsp_query-to>
      <Hsp_hit-from>137</Hsp_hit-from>
      <Hsp_hit-to>473</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>83</Hsp_identity>
      <Hsp_positive>139</Hsp_positive>
      <Hsp_gaps>68</Hsp_gaps>
      <Hsp_align-len>357</Hsp_align-len>
      <Hsp_qseq>ASIPTHRLFIHVRRLVAK-GYKVGVVKQTETTALKAAGENKSALFSRKLTALYTKSTLIGEDI--------LVNAVQP---------------------STGELLFDCFEDGKARLELESRVLSLQPVELLIPAALSDETERSLCSLTANSSQGXXXXXXXXXXXXLFEHSR---AFQAVSRFFGAESLQSNCNHDEQ-KLSHVLAMEKPIIACLAVLIH---YLTEFGL-----ERVLYL------SSTAIACTPYASIRQTNGKVKGSLLWAMDRTCTPFGRRMFRNWLGRPLISISDINARLDCVSEILASEHMVLSRAKELLWKLPDLERGLTSIYHRKCSTKEFSLIASSLE</Hsp_qseq>
      <Hsp_hseq>AGFPVHQLSRHLKMLVNNCGYSVTIAEQFKK---KDVADNEANKFYRRVTRIVTPGTFIDEAFENLRENTYLLNIEFPENCMSQVADTSLKVGICWCDVSTGEI----FVQQVYLRDLVSAITRIQPKEILLDERL----------LEFHIESGTWYPELVELKKFFIKYQKMPSQHRTIESFYGLFNLGGKEATERQLKIQFQTFTQKELAALRNTLIYVSNHLPDFSINFQIPQRQLATAIMQIDSRTSTALELHSTVRDNNKK--GSLLSSIRRTVTPSGTRLLSQWLSGPSLDLKEIKKRQKIVA-FFKDNRDITETLRTMLKKVNDLSRILQKFSFGRGEALELIQMARSLE</Hsp_hseq>
      <Hsp_midline>A  P H+L  H++ LV   GY V + +Q +    K   +N++  F R++T + T  T I E          L+N   P                     STGE+    F       +L S +  +QP E+L+   L          L  +   G     +  +     ++ +     + +  F+G  +L      + Q K+      +K + A    LI+   +L +F +     +R L        S T+ A   ++++R  N K  GSLL ++ RT TP G R+   WL  P + + +I  R   V+        +    + +L K+ DL R L      +    E   +A SLE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1263378718</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052703-RA transcript Note:&quot;Similar to MSH3 DNA mismatch repair protein Msh3 (Homo sapiens)&quot; offset:0 AED:0.32 eAED:0.32 QI:0|0.95|1|1|0.22|0.26|23|1128|377</Iteration_query-def>
  <Iteration_query-len>2262</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YCR092C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:276764:279820:-1 gene:YCR092C transcript:YCR092C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MSH3 description:Mismatch repair protein; forms dimers with Msh2p that mediate repair of insertion or deletion mutations and removal of nonhomologous DNA ends, contains a PCNA (Pol30p) binding motif required for genome stability [Source:SGD;Acc:S000000688]</Hit_def>
  <Hit_accession>YCR092C</Hit_accession>
  <Hit_len>1018</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>255.758</Hsp_bit-score>
      <Hsp_score>652</Hsp_score>
      <Hsp_evalue>3.06888e-73</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>1131</Hsp_query-to>
      <Hsp_hit-from>616</Hsp_hit-from>
      <Hsp_hit-to>1014</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>153</Hsp_identity>
      <Hsp_positive>225</Hsp_positive>
      <Hsp_gaps>60</Hsp_gaps>
      <Hsp_align-len>417</Hsp_align-len>
      <Hsp_qseq>RRSEEIRAVLEELREHRTEVRRTLRSPAADYTTVSGQEFLIEVRNSMLHTVPSNWVKIGR--------------------------------QFGE-------HYHNFRAAVAQLATLDCLFSLAAIASRDGYCRPEFVEEKSLIVIENGRHPVVELLMGDQNQYVPNSTHLDADGKRAMIITGPNMGGKSSYIRQVALIAVMAQMGSFVPASHAKLSSLHAIHTRMGASDNIYKGHSTFMEELSEASEIIRKATRHSLVILDELGRGTSTHDGIAIAYATLEYFVKEVQC-LTLFVTHYPPVCEMERLNAEVVSNYHMSFLLSEPEETVQGEDGERLESVTFLYQLTEGPAARSYGLNVARLAAIPEQVLHTAAQKSREL-EAHINMKR-KNISHFLRVWDLEEYEASNQLQTLFS</Hsp_qseq>
      <Hsp_hseq>RESESVRS---QLKEELAEIRKYLKRPYLNFR--DEVDYLIEVKNSQIKDLPDDWIKVNNTKMVSRFTTPRTQKLTQKLEYYKDLLIRESELQYKEFLNKITAEYTELRKITLNLAQYDCILSLAATSCNVNYVRPTFVNGQQAIIAKNARNPIIESL---DVHYVPNDIMMSPENGKINIITGPNMGGKSSYIRQVALLTIMAQIGSFVPAEEIRLSIFENVLTRIGAHDDIINGDSTFKVEMLDILHILKNCNKRSLLLLDEVGRGTGTHDGIAISYALIKYFSELSDCPLILFTTHFPMLGEIK---SPLIRNYHMDYV----EEQKTGEDW---MSVIFLYKLKKGLTYNSYGMNVAKLARLDKDIINRAFSISEELRKESINEDALKLFSSLKRILKSDNITATDKLAKLLS</Hsp_hseq>
      <Hsp_midline>R SE +R+   +L+E   E+R+ L+ P  ++      ++LIEV+NS +  +P +W+K+                                  Q+ E        Y   R     LA  DC+ SLAA +    Y RP FV  +  I+ +N R+P++E L      YVPN   +  +  +  IITGPNMGGKSSYIRQVAL+ +MAQ+GSFVPA   +LS    + TR+GA D+I  G STF  E+ +   I++   + SL++LDE+GRGT THDGIAI+YA ++YF +   C L LF TH+P + E++   + ++ NYHM ++    EE   GED     SV FLY+L +G    SYG+NVA+LA + + +++ A   S EL +  IN    K  S   R+   +   A+++L  L S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YOL090W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:147382:150276:1 gene:YOL090W transcript:YOL090W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MSH2 description:Protein that binds to DNA mismatches; forms heterodimers with Msh3p and Msh6p that bind to DNA mismatches to initiate the mismatch repair process; contains a Walker ATP-binding motif required for repair activity and involved in interstrand cross-link repair; Msh2p-Msh6p binds to and hydrolyzes ATP [Source:SGD;Acc:S000005450]</Hit_def>
  <Hit_accession>YOL090W</Hit_accession>
  <Hit_len>964</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>186.422</Hsp_bit-score>
      <Hsp_score>472</Hsp_score>
      <Hsp_evalue>1.19069e-49</Hsp_evalue>
      <Hsp_query-from>232</Hsp_query-from>
      <Hsp_query-to>1032</Hsp_query-to>
      <Hsp_hit-from>617</Hsp_hit-from>
      <Hsp_hit-to>880</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>103</Hsp_identity>
      <Hsp_positive>169</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>273</Hsp_align-len>
      <Hsp_qseq>LATLDCLFSLAAIASRDG--YCRPEF----VEEKSLIVIENGRHPVVELLMGDQNQYVPNSTHLDADGKRAMIITGPNMGGKSSYIRQVALIAVMAQMGSFVPASHAKLSSLHAIHTRMGASDNIYKGHSTFMEELSEASEIIRKATRHSLVILDELGRGTSTHDGIAIAYATLEYFVKEVQCLTLFVTHYPPVCEMERLNAEVVSNYHMSFLLSEPEETVQGEDGERLESVTFLYQLTEGPAARSYGLNVARLAAIPEQVLHTAAQKSRELE</Hsp_qseq>
      <Hsp_hseq>LAHLDVIASFAHTSSYAPIPYIRPKLHPMDSERRTHLI--SSRHPVLE--MQDDISFISNDVTLESGKGDFLIITGPNMGGKSTYIRQVGVISLMAQIGCFVPCEEAEIAIVDAILCRVGAGDSQLKGVSTFMVEILETASILKNASKNSLIIVDELGRGTSTYDGFGLAWAIAEHIASKIGCFALFATHFHELTEL----SEKLPNVKNMHVVAHIEKNLK-EQKHDDEDITLLYKVEPGISDQSFGIHVAEVVQFPEKIVKMAKRKANELD</Hsp_hseq>
      <Hsp_midline>LA LD + S A  +S     Y RP+      E ++ ++  + RHPV+E  M D   ++ N   L++     +IITGPNMGGKS+YIRQV +I++MAQ+G FVP   A+++ + AI  R+GA D+  KG STFM E+ E + I++ A+++SL+I+DELGRGTST+DG  +A+A  E+   ++ C  LF TH+  + E+    +E + N     +++  E+ ++ E     E +T LY++  G + +S+G++VA +   PE+++  A +K+ EL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YDR097C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:640109:643837:-1 gene:YDR097C transcript:YDR097C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MSH6 description:Protein required for mismatch repair in mitosis and meiosis; forms a complex with Msh2p to repair both single-base &amp; insertion-deletion mispairs; also involved in interstrand cross-link repair; potentially phosphorylated by Cdc28p [Source:SGD;Acc:S000002504]</Hit_def>
  <Hit_accession>YDR097C</Hit_accession>
  <Hit_len>1242</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>171.785</Hsp_bit-score>
      <Hsp_score>434</Hsp_score>
      <Hsp_evalue>1.2528e-44</Hsp_evalue>
      <Hsp_query-from>16</Hsp_query-from>
      <Hsp_query-to>1032</Hsp_query-to>
      <Hsp_hit-from>790</Hsp_hit-from>
      <Hsp_hit-to>1167</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>110</Hsp_identity>
      <Hsp_positive>179</Hsp_positive>
      <Hsp_gaps>63</Hsp_gaps>
      <Hsp_align-len>390</Hsp_align-len>
      <Hsp_qseq>EEIRAVLEELREHRTEVRRTLRSPAADYTTVSGQEFLIEVRNSMLHTVPSNWVKIG---------------------------------------RQFGEHYHN-FRAAVAQLATLDCLFSLAAIASRDG--YCRPEFVEE---------KSLIVIENGRHPVVELLMGDQNQYVPNSTHLDADGKRAMIITGPNMGGKSSYIRQVALIAVMAQMGSFVPASHAKLSSLHAIHTRMGASDNIYKGHSTFMEELSEASEIIRKATRHSLVILDELGRGTSTHDGIAIAYATLEYFVKEVQCLTLFVTHYPPVCEMERLNAEVVSNYHMSFLLSEPEETVQGEDGERLESVTFLYQLTEGPAARSYGLNVARLAAIPEQVLHTAAQKSRELE</Hsp_qseq>
      <Hsp_hseq>DRIQELEDELMEILMTYRKQFKCSNIQYKDSGKEIYTIEIPISATKNVPSNWVQMAANKTYKRYYSDEVRALARSMAEAKEIHKTLEEDLKNRLCQKFDAHYNTIWMPTIQAISNIDCLLAITRTSEYLGAPSCRPTIVDEVDSKTNTQLNGFLKFKSLRHPCFNLGATTAKDFIPNDIELGKEQPRLGLLTGANAAGKSTILRMACIAVIMAQMGCYVPCESAVLTPIDRIMTRLGANDNIMQGKSTFFVELAETKKILDMATNRSLLVVDELGRGGSSSDGFAIAESVLHHVATHIQSLGFFATHYGTLASSFKHHPQVRP-LKMSILVDEA-----------TRNVTFLYKMLEGQSEGSFGMHVASMCGISKEIIDNAQIAADNLE</Hsp_hseq>
      <Hsp_midline>+ I+ + +EL E     R+  +     Y     + + IE+  S    VPSNWV++                                        ++F  HY+  +   +  ++ +DCL ++   +   G   CRP  V+E            +  ++ RHP   L       ++PN   L  +  R  ++TG N  GKS+ +R   +  +MAQMG +VP   A L+ +  I TR+GA+DNI +G STF  EL+E  +I+  AT  SL+++DELGRG S+ DG AIA + L +    +Q L  F THY  +    + + +V     MS L+ E              +VTFLY++ EG +  S+G++VA +  I ++++  A   +  LE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YHR120W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:349574:352453:1 gene:YHR120W transcript:YHR120W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MSH1 description:DNA-binding protein of the mitochondria; involved in repair of mitochondrial DNA; has ATPase activity and binds to DNA mismatches; has homology to E. coli MutS; transcription is induced during meiosis [Source:SGD;Acc:S000001162]</Hit_def>
  <Hit_accession>YHR120W</Hit_accession>
  <Hit_len>959</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>167.548</Hsp_bit-score>
      <Hsp_score>423</Hsp_score>
      <Hsp_evalue>1.98057e-43</Hsp_evalue>
      <Hsp_query-from>184</Hsp_query-from>
      <Hsp_query-to>1008</Hsp_query-to>
      <Hsp_hit-from>687</Hsp_hit-from>
      <Hsp_hit-to>954</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>105</Hsp_identity>
      <Hsp_positive>154</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>279</Hsp_align-len>
      <Hsp_qseq>RQFGEHYHNFRAAVAQLATLDCLFSLAAIASRDGYCRPEFVEEKSLIVIENGRHPVVE--LLMGDQNQYVPNSTHLDADGKRAMIITGPNMGGKSSYIRQVALIAVMAQMGSFVPASHAKLSSLHAIHTRMGASDNIYKGHSTFMEELSEASEIIRKATRHSLVILDELGRGTSTHDGIAIAYATLEYFVKEVQCLTLFVTHYPPVCEMERLNAEVVSNYHMSFLLSEPEETVQGEDGERLESVTFLY--QLTEGPAARSYGLNVARLAAIPEQVLHTA</Hsp_qseq>
      <Hsp_hseq>RKFIDRSNEVRQVATTLGYLDTLSSFAVLANERNLVCPKVDESNKLEVV-NGRHLMVEEGLSARSLETFTANNCELAKDN--LWVITGPNMGGKSTFLRQNAIIVILAQIGCFVPCSKARVGIVDKLFSRVGSADDLYNEMSTFMVEMIETSFILQGATERSLAILDEIGRGTSGKEGISIAYATLKYLLENNQCRTLFATHFGQELK------QIIDN-KCSKGMSEKVKFYQSGITD-LGGNNFCYNHKLKPGICTKSDAIRVAELAGFPMEALKEA</Hsp_hseq>
      <Hsp_midline>R+F +  +  R     L  LD L S A +A+      P+  E   L V+ NGRH +VE  L       +  N+  L  D     +ITGPNMGGKS+++RQ A+I ++AQ+G FVP S A++  +  + +R+G++D++Y   STFM E+ E S I++ AT  SL ILDE+GRGTS  +GI+IAYATL+Y ++  QC TLF TH+    +      +++ N   S  +SE  +  Q    + L    F Y  +L  G   +S  + VA LA  P + L  A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YDL154W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:178334:181039:1 gene:YDL154W transcript:YDL154W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MSH5 description:Protein of the MutS family; forms a dimer with Msh4p that facilitates crossovers between homologs during meiosis; msh5-Y823H mutation confers tolerance to DNA alkylating agents; homologs present in C. elegans and humans [Source:SGD;Acc:S000002313]</Hit_def>
  <Hit_accession>YDL154W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>134.806</Hsp_bit-score>
      <Hsp_score>338</Hsp_score>
      <Hsp_evalue>4.924e-33</Hsp_evalue>
      <Hsp_query-from>259</Hsp_query-from>
      <Hsp_query-to>1023</Hsp_query-to>
      <Hsp_hit-from>575</Hsp_hit-from>
      <Hsp_hit-to>843</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>79</Hsp_identity>
      <Hsp_positive>144</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>273</Hsp_align-len>
      <Hsp_qseq>LAAIASRDGYCRPEFVEEKSLIVIENGRHPVVELLMGDQNQYVPNSTHLDA-----------DGKRAMIITGPNMGGKSSYIRQVALIAVMAQMGSFVPASHAKLSSLHAIHTRMGASDNIYKGHSTFMEELSEASEIIRKATRHSLVILDELGRGTSTHDGIAIAYATLEYFVKEVQCLTLF-VTHYPPVCEMERL--NAEVVSNYHMSFLLSEPEETVQ----GEDGERLESVTFLYQLTEGPAARSYGLNVARLAAIPEQVLHTAAQKSR</Hsp_qseq>
      <Hsp_hseq>FAQVSAERNYAEPQLVEDECILEIINGRHALYETFL---DNYIPNSTMIDGGLFSELSWCEQNKGRIIVVTGANASGKSVYLTQNGLIVYLAQIGCFVPAERARIGIADKILTRIRTQETVYKTQSSFLLDSQQMAKSLSLATEKSLILIDEYGKGTDILDGPSLFGSIMLNMSKSEKCPRIIACTHFHELFNENVLTENIKGIKHYCTDILISQKYNLLETAHVGEDHES-EGITFLFKVKEGISKQSFGIYCAKVCGLSRDIVERAEELSR</Hsp_hseq>
      <Hsp_midline> A +++   Y  P+ VE++ ++ I NGRH + E  +   + Y+PNST +D            +  R +++TG N  GKS Y+ Q  LI  +AQ+G FVPA  A++     I TR+   + +YK  S+F+ +  + ++ +  AT  SL+++DE G+GT   DG ++  + +    K  +C  +   TH+  +     L  N + + +Y    L+S+    ++    GED E  E +TFL+++ EG + +S+G+  A++  +   ++  A + SR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YFL003C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:134521:137157:-1 gene:YFL003C transcript:YFL003C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MSH4 description:Protein involved in meiotic recombination; required for normal levels of crossing over, colocalizes with Zip2p to discrete foci on meiotic chromosomes, has homology to bacterial MutS protein [Source:SGD;Acc:S000001891]</Hit_def>
  <Hit_accession>YFL003C</Hit_accession>
  <Hit_len>878</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>109.768</Hsp_bit-score>
      <Hsp_score>273</Hsp_score>
      <Hsp_evalue>3.34096e-25</Hsp_evalue>
      <Hsp_query-from>232</Hsp_query-from>
      <Hsp_query-to>996</Hsp_query-to>
      <Hsp_hit-from>571</Hsp_hit-from>
      <Hsp_hit-to>805</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>256</Hsp_align-len>
      <Hsp_qseq>LATLDCLFSLAAIASRDGYCRPEFVEEKSLIVIENGRHPVVELLMGDQNQYVPNSTHLDADGKRAMIITGPNMGGKSSYIRQVALIAVMAQMGSFVPASHAKLSSLHAIHTRMGASDNIYKGHSTFMEELSEASEIIRKATRHSLVILDELGRGTSTHDGIAIAYATLEYFVKEVQCLTLFVTHYPPVCEMERLNAEVVSNYHMSFLLSEPEETVQGEDGERLESVTFLYQLTEGPAA-RSYGLNVARLAAIPEQV</Hsp_qseq>
      <Hsp_hseq>VAILDLVCSFTYNLKENNYTIPIFTNN---LLIRDSRHPLLEKVLKN---FVPNTISSTKHSSSLQIITGCNMSGKSVYLKQVALICIMAQMGSGIPALYGSFPVFKRLHARV-CNDSMELTSSNFGFEMKEMAYFLDDINTETLLILDELGRGSSIADGFCVSLAVTEHLLR-TEATVFLSTHFQDIPKIMS-KKPAVSHLHMDAVLLND------------NSVKMNYQLTQKSVAIENSGIRVVKKIFNPDII</Hsp_hseq>
      <Hsp_midline>+A LD + S       + Y  P F      ++I + RHP++E ++ +   +VPN+           IITG NM GKS Y++QVALI +MAQMGS +PA +        +H R+  +D++    S F  E+ E +  +      +L+ILDELGRG+S  DG  ++ A  E+ ++  +      TH+  + ++       VS+ HM  +L                SV   YQLT+   A  + G+ V +    P+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1493930619</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0002716-RA transcript Note:&quot;Similar to Rasgrf2 Ras-specific guanine nucleotide-releasing factor 2 (Mus musculus)&quot; offset:0 AED:0.20 eAED:0.20 QI:0|0|0|0.5|0|0|2|0|93</Iteration_query-def>
  <Iteration_query-len>282</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>65</Statistics_hsp-len>
      <Statistics_eff-space>72066943</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0028118-RA transcript Note:&quot;Similar to Rasgrf1 Ras-specific guanine nucleotide-releasing factor 1 (Rattus norvegicus)&quot; offset:0 AED:0.21 eAED:0.22 QI:0|0.22|0.26|0.95|0.40|0.47|23|317|1002</Iteration_query-def>
  <Iteration_query-len>3326</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YLR310C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:752224:756993:-1 gene:YLR310C transcript:YLR310C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC25 description:Membrane bound guanine nucleotide exchange factor; also known as a GEF or GDP-release factor; indirectly regulates adenylate cyclase through activation of Ras1p and Ras2p by stimulating the exchange of GDP for GTP; required for progression through G1; thermosensitivity of the cdc25-5 mutant is functionally complemented by human RASGRF1 or by a fragment of human SOS1 comprising the CDC25-related catalytic domain [Source:SGD;Acc:S000004301]</Hit_def>
  <Hit_accession>YLR310C</Hit_accession>
  <Hit_len>1589</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>117.472</Hsp_bit-score>
      <Hsp_score>293</Hsp_score>
      <Hsp_evalue>5.19801e-27</Hsp_evalue>
      <Hsp_query-from>2383</Hsp_query-from>
      <Hsp_query-to>2997</Hsp_query-to>
      <Hsp_hit-from>1310</Hsp_hit-from>
      <Hsp_hit-to>1542</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>233</Hsp_align-len>
      <Hsp_qseq>AEQLTLLDFLVFRSIPYQEFLDRGWMKSDKN-ERAPKIMRTSKHFNEMSNLVAWEIASRMDVGARAAAIDKWVAVADICRCLHSYNTVLQITSALNRSAVYRLKKTWARVSKQTKALIDKLQKIVSSEGRFKNLRETLKSC-DPPCVPYVGMYLTDLAFIEEGTPNF--TEEGLVNFSKMRMVTRFL---------------LDRAHVCDDDSL---------YALSLQIEPR</Hsp_qseq>
      <Hsp_hseq>ATQLTVLEHDLYLRITMFECLDRAWGTKYCNMGGSPNITKFIANANTLTNFVSHTIVKQADVKTRSKLTQYFVTVAQHCKELNNFSSMTAIVSALYSSPIYRLKKTWDLVSTESKDLLKNLNNLMDSKRNFVKYRELLRSVTDVACVPFFGVYLSDLTFTFVGNPDFLHNSTNIINFSKRTKIANIVEEIISFKRFHYKLKRLDDIQTVIEASLENVPHIEKQYQLSLQVEPR</Hsp_hseq>
      <Hsp_midline>A QLT+L+  ++  I   E LDR W     N   +P I +   + N ++N V+  I  + DV  R+     +V VA  C+ L++++++  I SAL  S +YRLKKTW  VS ++K L+  L  ++ S+  F   RE L+S  D  CVP+ G+YL+DL F   G P+F      ++NFSK   +   +               LD      + SL         Y LSLQ+EPR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YAL024C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:101565:105872:-1 gene:YAL024C transcript:YAL024C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:LTE1 description:Protein similar to GDP/GTP exchange factors; without detectable GEF activity; required for asymmetric localization of Bfa1p at daughter-directed spindle pole bodies and for mitotic exit at low temperatures [Source:SGD;Acc:S000000022]</Hit_def>
  <Hit_accession>YAL024C</Hit_accession>
  <Hit_len>1435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.4034</Hsp_bit-score>
      <Hsp_score>176</Hsp_score>
      <Hsp_evalue>3.72758e-13</Hsp_evalue>
      <Hsp_query-from>2332</Hsp_query-from>
      <Hsp_query-to>2931</Hsp_query-to>
      <Hsp_hit-from>1183</Hsp_hit-from>
      <Hsp_hit-to>1398</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>217</Hsp_align-len>
      <Hsp_qseq>NEEMKPEQFEYLSVLELAEQLTLLDFLVFRSIPYQEFLDR----------GWMKS-DKNERAPKIMRTSKHFNEMSNLVAWEIASRMDVGARAAAIDKWVAVADICRCLHSYNTVLQITSALNRSAVYRLKKTWARVSKQTKALIDKLQKIVSSEGRFKNLRETLKSCDP--PCVPYVGMYLTDLAFIEEGTPNFTEEGLVNFSK----MRMVTRFL</Hsp_qseq>
      <Hsp_hseq>NESHVPFILMYDS-LSVAQQMTLIEKEILGEIDWKDLLDLKMKHEGPQVISWLQLLVRNETLSGIDLAISRFNLTVDWIISEILLTKSSKMKRNVIQRFIHVADHCRTFQNFNTLMEIILALSSSVVQKFTDAWRLIEPGDLLTWEELKKIPSLDRNYSTIRNLLNSVNPLVGCVPFIVVYLSDLSANAEKKDWILEDKVVNYNKFDTNVQIVKNFI</Hsp_hseq>
      <Hsp_midline>NE   P    Y S L +A+Q+TL++  +   I +++ LD            W++   +NE    I      FN   + +  EI        +   I +++ VAD CR   ++NT+++I  AL+ S V +    W  +        ++L+KI S +  +  +R  L S +P   CVP++ +YL+DL+   E      E+ +VN++K    +++V  F+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YCR038C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:197621:199549:-1 gene:YCR038C transcript:YCR038C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BUD5 description:GTP/GDP exchange factor for Rsr1p (Bud1p); required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types [Source:SGD;Acc:S000000634]</Hit_def>
  <Hit_accession>YCR038C</Hit_accession>
  <Hit_len>642</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>3.75646e-08</Hsp_evalue>
      <Hsp_query-from>2581</Hsp_query-from>
      <Hsp_query-to>2931</Hsp_query-to>
      <Hsp_hit-from>471</Hsp_hit-from>
      <Hsp_hit-to>588</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>121</Hsp_align-len>
      <Hsp_qseq>AIDKWVAVADICRCLHSYNTVLQITSALNRSAVYRLKKTWARVSKQTKALIDKLQKIVSSEGRFKNLRETLKSC---DPPCVPYVGMYLTDLAFIEEGTPNFTEEG-LVNFSKMRMVTRFL</Hsp_qseq>
      <Hsp_hseq>TISYWLQVALSCLYLRNLNSLASIITSLQNHSIERLS---LPIDVKSDHLFQRLKVVVHPNNNYNVYRRTIKHIFHSQLPCVPFTSLLIRDITFIRDGNDTFTKDGNNVNMQKFNQITKIV</Hsp_hseq>
      <Hsp_midline> I  W+ VA  C  L + N++  I ++L   ++ RL      +  ++  L  +L+ +V     +   R T+K       PCVP+  + + D+ FI +G   FT++G  VN  K   +T+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2272099536</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052704-RA transcript Note:&quot;Similar to Arl14ep ARL14 effector protein (Mus musculus)&quot; offset:19 AED:0.02 eAED:0.02 QI:19|1|1|1|0.5|0.66|3|824|136</Iteration_query-def>
  <Iteration_query-len>1254</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>92</Statistics_hsp-len>
      <Statistics_eff-space>752038642</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052706-RA transcript Note:&quot;Similar to Chymotrypsin B (Gadus morhua)&quot; offset:0 AED:0.05 eAED:0.05 QI:0|0.25|0.2|1|0.75|0.8|5|1556|212</Iteration_query-def>
  <Iteration_query-len>2195</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1441631678</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052710-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.46 eAED:0.48 QI:0|-1|0|1|-1|1|1|0|78</Iteration_query-def>
  <Iteration_query-len>237</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>51</Statistics_hsp-len>
      <Statistics_eff-space>72169076</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0026458-RA transcript Note:&quot;Similar to Ntrk3 NT-3 growth factor receptor (Mus musculus)&quot; offset:729 AED:0.68 eAED:0.77 QI:729|0.18|0.16|0.58|0.18|0.25|12|0|431</Iteration_query-def>
  <Iteration_query-len>2025</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1320390393</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0039258-RA transcript Note:&quot;Similar to NTRK3 NT-3 growth factor receptor (Gallus gallus)&quot; offset:0 AED:0.31 eAED:0.31 QI:0|-1|0|1|-1|0|1|82|102</Iteration_query-def>
  <Iteration_query-len>391</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>79</Statistics_hsp-len>
      <Statistics_eff-space>122026017</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052712-RA transcript Note:&quot;Similar to NAA35 N-alpha-acetyltransferase 35, NatC auxiliary subunit (Macaca fascicularis)&quot; offset:554 AED:0.16 eAED:0.16 QI:554|0.70|0.88|0.94|0.35|0.44|18|1644|526</Iteration_query-def>
  <Iteration_query-len>3779</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2602566786</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

