<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0051709-RA transcript Note:&quot;Similar to Fmnl2 Formin-like protein 2 (Mus musculus)&quot; offset:13 AED:0.07 eAED:0.07 QI:13|0.84|0.88|0.96|0.52|0.65|26|2880|988</BlastOutput_query-def>
  <BlastOutput_query-len>5860</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0051709-RA transcript Note:&quot;Similar to Fmnl2 Formin-like protein 2 (Mus musculus)&quot; offset:13 AED:0.07 eAED:0.07 QI:13|0.84|0.88|0.96|0.52|0.65|26|2880|988</Iteration_query-def>
  <Iteration_query-len>5860</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YIL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:41825:45952:1 gene:YIL159W transcript:YIL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BNR1 description:Formin; nucleates the formation of linear actin filaments; involved in processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables; activity is regulated by Hof1p and by the Bud14p-Kel1p-Kel2p complex; dephosphorylated and delocalized from the division site in a Glc7p/Ref2p-dependent manner; functionally redundant with BNI1 [Source:SGD;Acc:S000001421]</Hit_def>
  <Hit_accession>YIL159W</Hit_accession>
  <Hit_len>1375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>1.1983e-10</Hsp_evalue>
      <Hsp_query-from>2186</Hsp_query-from>
      <Hsp_query-to>2680</Hsp_query-to>
      <Hsp_hit-from>1100</Hsp_hit-from>
      <Hsp_hit-to>1279</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>184</Hsp_align-len>
      <Hsp_qseq>FGNYMNSSKRGAVYGFKLQSLDLLIETKST-DRKLTLLHYISNIVQHKYPDLVTFYNELRYIEKAAAVSMENVLQDVRELQRGMD----------LTKREFSMHESNTLLREF---LAPSEARLERLLSDTKTAQEAYNTVVQYFGENPKTT-PPSVFFPLLVRFVKAYKQAELDN----EMKR</Hsp_qseq>
      <Hsp_hseq>IGNHMN---KRIVKGIKLKSLTKLAFVRSSIDQNVSFLHFIEKVIRIKYPDIYGFVDDLKNIEDLGKISLEHVESECHEFHKKIEDLVTQFQVGKLSKEE-NLDPRDQIIKKVKFKINRAKTKSELLIGQCKLTLIDLNKLMKYYGEDPKDKESKNEFFQPFIEFLAMFKKCAKENIEKEEMER</Hsp_hseq>
      <Hsp_midline> GN+MN   +  V G KL+SL  L   +S+ D+ ++ LH+I  +++ KYPD+  F ++L+ IE    +S+E+V  +  E  + ++          L+K E ++   + ++++    +  ++ + E L+   K      N +++Y+GE+PK     + FF   + F+  +K+   +N    EM+R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YNL271C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:129522:135383:-1 gene:YNL271C transcript:YNL271C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BNI1 description:Formin; polarisome component; nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables; recruited to the division site in a Glc7p/Ref2p dependent manner following release of Bnr1p; functionally redundant with BNR1 [Source:SGD;Acc:S000005215]</Hit_def>
  <Hit_accession>YNL271C</Hit_accession>
  <Hit_len>1953</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>1.67919e-07</Hsp_evalue>
      <Hsp_query-from>2189</Hsp_query-from>
      <Hsp_query-to>2668</Hsp_query-to>
      <Hsp_hit-from>1576</Hsp_hit-from>
      <Hsp_hit-to>1747</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>173</Hsp_align-len>
      <Hsp_qseq>GNYMNSSKRGAVYGFKLQSLDLLIETKSTDRKLTLLHYISNIVQHKYPDLVTFYNELRYIEKAAAVSMENVLQDVRELQRGMDLTKREFSM---------HESNTLLREFLA--PSEARLERLLSD-TKTAQEAYNTVVQYFGENPKTTPPSV-FFPLLVRFVKAYKQAELDN</Hsp_qseq>
      <Hsp_hseq>GNFMNDTSKQA-QGFKLSTLQRLTFIKDTTNSMTFLNYVEKIVRLNYPSFNDFLSELEPVLDVVKVSIEQLVNDCKDFSQSIVNVERSVEIGNLSDSSKFHPLDKVLIKTLPVLPEARKKGDLLEDEVKLTIMEFESLMHTYGEDSGDKFAKISFFKKFADFINEYKKAQAQN</Hsp_hseq>
      <Hsp_midline>GN+MN + + A  GFKL +L  L   K T   +T L+Y+  IV+  YP    F +EL  +     VS+E ++ D ++  + +   +R   +         H  + +L + L   P   +   LL D  K     + +++  +GE+       + FF     F+  YK+A+  N</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>104</Statistics_hsp-len>
      <Statistics_eff-space>4118956283</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0004780-RA transcript Note:&quot;Similar to MYLK Myosin light chain kinase, smooth muscle (Bos taurus)&quot; offset:0 AED:0.28 eAED:0.29 QI:0|0|0|0.8|0.42|0.5|20|0|1337</Iteration_query-def>
  <Iteration_query-len>4014</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>124.405</Hsp_bit-score>
      <Hsp_score>311</Hsp_score>
      <Hsp_evalue>6.45439e-29</Hsp_evalue>
      <Hsp_query-from>2299</Hsp_query-from>
      <Hsp_query-to>3015</Hsp_query-to>
      <Hsp_hit-from>196</Hsp_hit-from>
      <Hsp_hit-to>427</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>82</Hsp_identity>
      <Hsp_positive>132</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>243</Hsp_align-len>
      <Hsp_qseq>ISGGELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLAR-KLENVKNLKVMFGTPEFVAPEVINYEPI-GYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWLQMDTEHMAAKKLSKERMKRYLTKRNPKSPPAINDVSGYPDPEVIWFRNGQPIKES--RQLQI</Hsp_qseq>
      <Hsp_hseq>VDGGELFDYLVSKG-KLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLL-LDKKNRRIKIADFGMAALELPN-KLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMP----SNLSSEARDLISKILVIDPEKRITTQEILKHPLIKKYDDLPVNKVLRKMRKDNMARGKSNSDLHLLNNVS----PSIVTLHSKGEIDESILRSLQI</Hsp_hseq>
      <Hsp_midline>+ GGELF+ ++ +  +L ERE I Y +QIVEGV + H   I H DLKPEN++ L++   RIKI DFG+A  +L N K LK   G+P + +PE++   P  G  +D+WS G++ + L++G  P   DN  + L  V S  +         +S +++D IS +L  + ++R+T  + ++HP ++   +    K L K R       ++      +N+VS    P ++   +   I ES  R LQI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>115.161</Hsp_bit-score>
      <Hsp_score>287</Hsp_score>
      <Hsp_evalue>2.57673e-27</Hsp_evalue>
      <Hsp_query-from>2302</Hsp_query-from>
      <Hsp_query-to>2835</Hsp_query-to>
      <Hsp_hit-from>129</Hsp_hit-from>
      <Hsp_hit-to>309</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>182</Hsp_align-len>
      <Hsp_qseq>SGGELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNR-IKIIDFGLARKLENVKNLKV-MFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATW--DFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWL</Hsp_qseq>
      <Hsp_hseq>TGGELFDRILSRG-KFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSPFIAESVEGFMEECTASRYPVTFHMPYWDNISIDVKRFILKALRLNPADRPTATELLDDPWI</Hsp_hseq>
      <Hsp_midline>+GGELF+RI+    + TE + ++ + QI+  V++MH + +VH DLKPEN++ ++++ N  + I DFG+A++L+  ++L     G+  +VAPEV+  +  G   D+WS+GVI Y L+ G SP + ++    +   T++ +   F    +D IS D K FI   L+ N  +R T T+ ++ PW+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>115.161</Hsp_bit-score>
      <Hsp_score>287</Hsp_score>
      <Hsp_evalue>2.60386e-26</Hsp_evalue>
      <Hsp_query-from>2308</Hsp_query-from>
      <Hsp_query-to>2970</Hsp_query-to>
      <Hsp_hit-from>112</Hsp_hit-from>
      <Hsp_hit-to>333</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>121</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>228</Hsp_align-len>
      <Hsp_qseq>GELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINYEPI-GYATDMWSVGVICYILVSGLSPLMGDNDN--ETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWL---QMDTEHMAAKKLSKERMKRY-LTKRNPKSPPAINDVSGYPDPEVIW</Hsp_qseq>
      <Hsp_hseq>GELFNLLVDHG-PLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLL--DSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDT--EISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSASIDD-SILQNLVVLW</Hsp_hseq>
      <Hsp_midline>GELF  ++D    L ERE I   RQI+ G+ + H  GIVH DLKPEN++    +   IKI DFG+A    +   L+   G+P + APE+++  P  G+A+D+WS GVI + L++G  P   +N N  + L  V    ++  ++   EIS D++D I  +L  + ++R+     + HP L   Q   +  + K L +E    Y L   N  +  +I+D S   +  V+W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>110.923</Hsp_bit-score>
      <Hsp_score>276</Hsp_score>
      <Hsp_evalue>5.81579e-26</Hsp_evalue>
      <Hsp_query-from>2305</Hsp_query-from>
      <Hsp_query-to>2835</Hsp_query-to>
      <Hsp_hit-from>120</Hsp_hit-from>
      <Hsp_hit-to>299</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>181</Hsp_align-len>
      <Hsp_qseq>GGELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNR-IKIIDFGLARKLENVKNLKVM-FGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATW--DFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWL</Hsp_qseq>
      <Hsp_hseq>GGELFDRILKKG-KFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAELLEDPWI</Hsp_hseq>
      <Hsp_midline>GGELF+RI+ +  + TE + ++ + +I+  V++MH Q IVH DLKPEN++ ++++    + + DFG+A++L++ + L     G+  +VAPEV+  +  G   D+WS+GVI Y L+ G S    +   + L   T+  +   F    +D +S  +K FI   L  +  +R T  + +E PW+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>114.005</Hsp_bit-score>
      <Hsp_score>284</Hsp_score>
      <Hsp_evalue>6.97456e-26</Hsp_evalue>
      <Hsp_query-from>2308</Hsp_query-from>
      <Hsp_query-to>2838</Hsp_query-to>
      <Hsp_hit-from>116</Hsp_hit-from>
      <Hsp_hit-to>290</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>178</Hsp_align-len>
      <Hsp_qseq>GELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINYEPI-GYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWLQ</Hsp_qseq>
      <Hsp_hseq>GELFNLLV-ERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLL-LDHKYN-IKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERRIKTRDILKHPLLQ</Hsp_hseq>
      <Hsp_midline>GELF  ++ E   L E E I++ RQI+ GV + H  GIVH DLKPEN++ L+   N IKI DFG+A      K L+   G+P + APE+++  P  G+A+D+WS GVI + L++G  P   ++ N     +     +F+  + DEIS +++D I  +L  + + R+     ++HP LQ</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>110.153</Hsp_bit-score>
      <Hsp_score>274</Hsp_score>
      <Hsp_evalue>1.82295e-25</Hsp_evalue>
      <Hsp_query-from>2299</Hsp_query-from>
      <Hsp_query-to>2835</Hsp_query-to>
      <Hsp_hit-from>244</Hsp_hit-from>
      <Hsp_hit-to>444</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>201</Hsp_align-len>
      <Hsp_qseq>ISGGELFERIIDED--FELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIM-CLNQTGNRIKIIDFGLARKLE-NVKNLKVMFGTPEFVAPEV---------------INYEPIGYAT--DMWSVGVICYILVSGLSPLMGD-NDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWL</Hsp_qseq>
      <Hsp_hseq>IPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGISPFYGDGSERSIIQNAKIGKLNFKLKQWDIVSDNAKSFVKDLLQTDVVKRLNSKQGLKHIWI</Hsp_hseq>
      <Hsp_midline>I GG+LF  +   D    ++E E +  + QI++ + ++H Q IVH DLK +NI+ C  +   RI + DFG+A+ L  N + +  + GTPE+ APEV                  E  GY +  D+WS+GVI +I+++G+SP  GD ++   + N      +F  + +D +S+++K F+  LLQ ++ +RL   Q ++H W+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>107.457</Hsp_bit-score>
      <Hsp_score>267</Hsp_score>
      <Hsp_evalue>1.7594e-24</Hsp_evalue>
      <Hsp_query-from>2296</Hsp_query-from>
      <Hsp_query-to>2889</Hsp_query-to>
      <Hsp_hit-from>284</Hsp_hit-from>
      <Hsp_hit-to>497</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>217</Hsp_align-len>
      <Hsp_qseq>RISGGELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGN------------------RIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLA-NVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWLQMDTEHMAAKKLSKERMK</Hsp_qseq>
      <Hsp_hseq>KIDDGELFERIVRKTC-LRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENIL-LNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVILYVCLCGFPPFSDQLGPPSLKEQILQAKYAFYSPYWDKIDDSVLHLISNLLVLNPDERYNIDEALNHPWFN-DIQQQSSVSLELQRLQ</Hsp_hseq>
      <Hsp_midline>+I  GELFERI+ +   L + E     +Q++ G++++H Q I+H D+KPENI+ LN T                    ++KI DFGLA+    ++    + GTP +VAPEV+  +      D+WS GVI Y+ + G  P        +L   +  A + F    +D+I +     IS+LL  N  ER    + + HPW   D +  ++  L  +R++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>104.76</Hsp_bit-score>
      <Hsp_score>260</Hsp_score>
      <Hsp_evalue>4.5836e-23</Hsp_evalue>
      <Hsp_query-from>2299</Hsp_query-from>
      <Hsp_query-to>2835</Hsp_query-to>
      <Hsp_hit-from>205</Hsp_hit-from>
      <Hsp_hit-to>377</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>180</Hsp_align-len>
      <Hsp_qseq>ISGGELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINYEP-IGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWL</Hsp_qseq>
      <Hsp_hseq>VSGGQLLDYIIQHG-SLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMI--SSSGEIKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYP----SHLSIEVISLLTRMIVVDPLRRATLKNVVEHPWM</Hsp_hseq>
      <Hsp_midline>+SGG+L + II     L E    K+ R I   +Q++H   IVH DLK ENIM    +   IKIIDFGL+   +  K L    G+  F APE++  +P  G   D+WS G++ Y+LV G  P   +N +     +     D+       +S +    ++ ++  +   R T    VEHPW+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>103.605</Hsp_bit-score>
      <Hsp_score>257</Hsp_score>
      <Hsp_evalue>8.31614e-23</Hsp_evalue>
      <Hsp_query-from>2299</Hsp_query-from>
      <Hsp_query-to>2841</Hsp_query-to>
      <Hsp_hit-from>276</Hsp_hit-from>
      <Hsp_hit-to>468</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>194</Hsp_align-len>
      <Hsp_qseq>ISGGELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVI-----NYEPIGY--------ATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWLQM</Hsp_qseq>
      <Hsp_hseq>VSGGDLMD-FVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGPLKDFRISEEARDFIDSLLQVDPNNRSTAAKALNHPWIKM</Hsp_hseq>
      <Hsp_midline>+SGG+L +  +     + E    +  RQI+  ++++H  GI H DLKP+NI+        +KI DFGLA+   N   +K   GT  +VAPEVI     +  P  Y          DMWS+G + Y++++G  P  G   ++    +   ++         ISE+++DFI  LLQ +   R T  + + HPW++M</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>103.605</Hsp_bit-score>
      <Hsp_score>257</Hsp_score>
      <Hsp_evalue>8.97858e-23</Hsp_evalue>
      <Hsp_query-from>2359</Hsp_query-from>
      <Hsp_query-to>2838</Hsp_query-to>
      <Hsp_hit-from>133</Hsp_hit-from>
      <Hsp_hit-to>288</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>161</Hsp_align-len>
      <Hsp_qseq>ECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINYEPI-GYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWLQ</Hsp_qseq>
      <Hsp_hseq>ECGELFAQISGAVYYAHSMHCVHRDLKLENIL-LDKNGN-AKLTDFGFTRECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDAKV---IPDDARDLISRLLAKNPGERPSLSQVLRHPFLQ</Hsp_hseq>
      <Hsp_midline>EC +   QI   V + H    VH DLK ENI+ L++ GN  K+ DFG  R+      L+ + GT  ++APE+I      G+  D+WS+GVI Y L++G  P   D++ +T   + +    +D +    I +D++D IS LL KN  ER + +Q + HP+LQ</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>98.5969</Hsp_bit-score>
      <Hsp_score>244</Hsp_score>
      <Hsp_evalue>3.91522e-22</Hsp_evalue>
      <Hsp_query-from>2299</Hsp_query-from>
      <Hsp_query-to>2838</Hsp_query-to>
      <Hsp_hit-from>167</Hsp_hit-from>
      <Hsp_hit-to>342</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>185</Hsp_align-len>
      <Hsp_qseq>ISGGELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQ-----CVEHPWLQ</Hsp_qseq>
      <Hsp_hseq>IEGGELFS-LLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENIL-LDKNGH-IKITDFGFAKYVPDVT--YTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRF--PPF--FNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFK</Hsp_hseq>
      <Hsp_midline>I GGELF  ++ +           Y  ++   ++++H + I++ DLKPENI+ L++ G+ IKI DFG A+ + +V     + GTP+++APEV++ +P   + D WS G++ Y +++G +P    N  +T   + +A   F    F   +ED KD +S L+ +++ +RL   Q        HPW +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>98.2117</Hsp_bit-score>
      <Hsp_score>243</Hsp_score>
      <Hsp_evalue>4.80348e-22</Hsp_evalue>
      <Hsp_query-from>2299</Hsp_query-from>
      <Hsp_query-to>2835</Hsp_query-to>
      <Hsp_hit-from>168</Hsp_hit-from>
      <Hsp_hit-to>342</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>184</Hsp_align-len>
      <Hsp_qseq>ISGGELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQ-----CVEHPWL</Hsp_qseq>
      <Hsp_hseq>IEGGELFS-LLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENIL-LDKNGH-IKITDFGFAKYVPDVT--YTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFP----PFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWF</Hsp_hseq>
      <Hsp_midline>I GGELF  ++ +           Y  ++   ++++H + I++ DLKPENI+ L++ G+ IKI DFG A+ + +V     + GTP+++APEV++ +P   + D WS GV+ Y +++G +P    N  +T  N+ +A   F          D++D +  L+ +++ ERL   Q        HPW </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>100.138</Hsp_bit-score>
      <Hsp_score>248</Hsp_score>
      <Hsp_evalue>1.37266e-21</Hsp_evalue>
      <Hsp_query-from>2299</Hsp_query-from>
      <Hsp_query-to>2835</Hsp_query-to>
      <Hsp_hit-from>226</Hsp_hit-from>
      <Hsp_hit-to>398</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>180</Hsp_align-len>
      <Hsp_qseq>ISGGELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINYEP-IGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWL</Hsp_qseq>
      <Hsp_hseq>VSGGQLLDYIIQHG-SIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSS--EIKIIDFGLSNIYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKIKQGKVEYP----QHLSIEVISLLSKMLVVDPKRRATLKQVVEHHWM</Hsp_hseq>
      <Hsp_midline>+SGG+L + II     + E +  K+ R I   + ++H   IVH DLK ENIM  + +   IKIIDFGL+   ++ K L    G+  F APE++   P  G   D+WS GV+ ++LV G  P   +N +     +     ++       +S +    +S +L  + K R T  Q VEH W+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>96.2857</Hsp_bit-score>
      <Hsp_score>238</Hsp_score>
      <Hsp_evalue>5.92141e-21</Hsp_evalue>
      <Hsp_query-from>2299</Hsp_query-from>
      <Hsp_query-to>2838</Hsp_query-to>
      <Hsp_hit-from>216</Hsp_hit-from>
      <Hsp_hit-to>415</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>205</Hsp_align-len>
      <Hsp_qseq>ISGGELFERIIDEDFELT---ERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMC----------------------LNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWLQ</Hsp_qseq>
      <Hsp_hseq>VTGGEIFDRIV----QLTCFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLRN-NTAKTPCGTIEYVASEVFTSKRYSMKVDMWSIGCVLFTLLCGYPPFYEKNEKTLLKKISRGDYEFLAPWWDNISSGAKNAVTHLLEVDPNKRYDIDDFLNDPWLN</Hsp_hseq>
      <Hsp_midline>++GGE+F+RI+    +LT   E      + Q+   ++ MH  GIVH D+KPEN++                              +K++DFGLA+KL N    K   GT E+VA EV   +      DMWS+G + + L+ G  P    N+   L  ++   ++F    +D IS  +K+ ++HLL+ +  +R      +  PWL </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.9005</Hsp_bit-score>
      <Hsp_score>237</Hsp_score>
      <Hsp_evalue>1.92436e-20</Hsp_evalue>
      <Hsp_query-from>2305</Hsp_query-from>
      <Hsp_query-to>2838</Hsp_query-to>
      <Hsp_hit-from>578</Hsp_hit-from>
      <Hsp_hit-to>778</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>205</Hsp_align-len>
      <Hsp_qseq>GGELFERIIDEDFE-LTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVK----------------------NLKVMFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTC----TQCVEHPWLQ</Hsp_qseq>
      <Hsp_hseq>GGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENIL-LHQSGH-IMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKNEVSFPNN--NEISRTCKDLIKKLLTKNESKRLGCKMGAADVKKHPFFK</Hsp_hseq>
      <Hsp_midline>GGE F  +     + + E +   Y  ++   ++++H  G ++ DLKPENI+ L+Q+G+ I + DF L+ + ++ K                            GT E++APEVI       A D W++G++ Y ++ G +P  GDN NET  N+      F +   +EIS   KD I  LL KN  +RL C        +HP+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>94.7449</Hsp_bit-score>
      <Hsp_score>234</Hsp_score>
      <Hsp_evalue>2.85476e-20</Hsp_evalue>
      <Hsp_query-from>2281</Hsp_query-from>
      <Hsp_query-to>2844</Hsp_query-to>
      <Hsp_hit-from>128</Hsp_hit-from>
      <Hsp_hit-to>309</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>189</Hsp_align-len>
      <Hsp_qseq>IGRAIRISGGELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINYEPI-GYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWLQMD</Hsp_qseq>
      <Hsp_hseq>IIMVIEYAGNELFDYIVQRD-KMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLL-LDEHLN-VKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTL--PKF--LSPGAAGLIKRMLIVNPLNRISIHEIMQDDWFKVD</Hsp_hseq>
      <Hsp_midline>I   I  +G ELF+ I+  D +++E+E  ++ +QI+  V++ HR  IVH DLKPEN++ L++  N +KI DFGL+  + +   LK   G+P + APEVI+ +   G   D+WS GVI Y+++    P   ++      N+++  +      F  +S  +   I  +L  N   R++  + ++  W ++D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.1301</Hsp_bit-score>
      <Hsp_score>235</Hsp_score>
      <Hsp_evalue>4.01206e-20</Hsp_evalue>
      <Hsp_query-from>2371</Hsp_query-from>
      <Hsp_query-to>2838</Hsp_query-to>
      <Hsp_hit-from>283</Hsp_hit-from>
      <Hsp_hit-to>444</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>168</Hsp_align-len>
      <Hsp_qseq>YMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNL------------KVMFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWLQ</Hsp_qseq>
      <Hsp_hseq>YAAQIIDAIDYLHSNGIIHRDIKPENILLDGEM--KIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKVQYAF-TPGFPLI---IRDLVKKILVKNLDRRLTISQIKEHHFFK</Hsp_hseq>
      <Hsp_midline>Y  QI++ + ++H  GI+H D+KPENI+   +   +IK+ DFG A+ L    N             K   GT E+V+PE++N     Y  D+W+ G I + +++G  P    N+  T   V    + F    F  I    +D +  +L KN+  RLT +Q  EH + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>94.3597</Hsp_bit-score>
      <Hsp_score>233</Hsp_score>
      <Hsp_evalue>5.62827e-20</Hsp_evalue>
      <Hsp_query-from>2305</Hsp_query-from>
      <Hsp_query-to>2937</Hsp_query-to>
      <Hsp_hit-from>406</Hsp_hit-from>
      <Hsp_hit-to>623</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>235</Hsp_align-len>
      <Hsp_qseq>GGELFERIIDEDFE-LTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKN-------------------LKVMFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERL----TCTQCVEHPWLQMDTEHMAAKKLSKERMKRYLTKRNPKSPPAIND</Hsp_qseq>
      <Hsp_hseq>GGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENIL-LHQSGH-VMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKFPHDK--EVSKNCKDLIKKLLNKNEAKRLGSKSGAADIKRHPFF-------------KKVQWSFLRNQDPPLIPALND</Hsp_hseq>
      <Hsp_midline>GGE F  +     + + E +   Y  ++V  ++++H  G ++ DLKPENI+ L+Q+G+ + + DF L+ +    K                         GT E++APEVI       A D W++G++ Y ++ G +P  GDN NET +N+ +    F  +   E+S++ KD I  LL KN  +RL           HP+              K+    +L  ++P   PA+ND</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.8929</Hsp_bit-score>
      <Hsp_score>224</Hsp_score>
      <Hsp_evalue>6.78523e-19</Hsp_evalue>
      <Hsp_query-from>2263</Hsp_query-from>
      <Hsp_query-to>2940</Hsp_query-to>
      <Hsp_hit-from>121</Hsp_hit-from>
      <Hsp_hit-to>344</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>235</Hsp_align-len>
      <Hsp_qseq>NCRFVGIGRAIRISGGELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARK-LENVKNLKVMFGTPEFVAPEVI----NYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEA---FDE-ISEDSKDFISHLLQKNMKERLTCTQCVEHPWLQMDTEHMAAKKLSKERMKRYLTKRNPKSPPAINDV</Hsp_qseq>
      <Hsp_hseq>NSKYIGIVLEF-VSGGE-FYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLL-LDKHENLV-ITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYE--ARKADVWSCGVILYAMLAGYLPWDDDHENPTGDDI-ARLYKYITQTPLKFPEYITPIPRDLLRRILVPNPRRRINLQTIKRHVWLK---PHEAFLSIQPNYWDEHLQKERPK-PPNKGDV</Hsp_hseq>
      <Hsp_midline>N +++GI     +SGGE F + I     L E    +   Q++ GV +MH +G+VH DLK EN++ L++  N + I DFG   +  E+ + +K   G+P + APE++     YE      D+WS GVI Y +++G  P   D++N T  ++ +  + +  +    F E I+   +D +  +L  N + R+       H WL+    H A   +       +L K  PK PP   DV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.1965</Hsp_bit-score>
      <Hsp_score>217</Hsp_score>
      <Hsp_evalue>7.15239e-19</Hsp_evalue>
      <Hsp_query-from>2203</Hsp_query-from>
      <Hsp_query-to>2871</Hsp_query-to>
      <Hsp_hit-from>168</Hsp_hit-from>
      <Hsp_hit-to>367</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>223</Hsp_align-len>
      <Hsp_qseq>YGISEPSQESPLVSPGIVNGNCRFVGIGRAIRISGGELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWLQMDTEHMAAKKL</Hsp_qseq>
      <Hsp_hseq>YGYFHDEKRVYLLMEYLVNGE-----MYKLLRLHGP--FNDILASD----------YIYQIANALDYMHKKNIIHRDIKPENILI--GFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAA----LDIKMPSNISQDAQDLILKLLKYDPKDRMRLGDVKMHPWILRNKPFWENKRL</Hsp_hseq>
      <Hsp_midline>YG     +   L+   +VNG      + + +R+ G   F  I+  D          Y+ QI   + +MH++ I+H D+KPENI+      N IK+ DFG +         K + GT ++++PE++      +  D W++GV+ + L++G  P   +  + T   + +     D +    IS+D++D I  LL+ + K+R+       HPW+  +      K+L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.1225</Hsp_bit-score>
      <Hsp_score>222</Hsp_score>
      <Hsp_evalue>1.3342e-18</Hsp_evalue>
      <Hsp_query-from>2299</Hsp_query-from>
      <Hsp_query-to>2871</Hsp_query-to>
      <Hsp_hit-from>495</Hsp_hit-from>
      <Hsp_hit-to>684</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>199</Hsp_align-len>
      <Hsp_qseq>ISGGELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMF-GTPEFVAPEVINYEPIGYA--TDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCT----QCVEHPWL-QMDTEHMAAKKL</Hsp_qseq>
      <Hsp_hseq>MSGGELFWHLQKEG-RFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENIL-LDANGN-IALCDFGLSKA--DLKDRTNTFCGTTEYLAPELL-LDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPR---DVLSQEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFADIDWEALKQKKI</Hsp_hseq>
      <Hsp_midline>+SGGELF  +  E    +E     Y+ ++V  ++ +H   IV+ DLKPENI+ L+  GN I + DFGL++   ++K+    F GT E++APE++  +  GY    D WS+GV+ + +  G SP   +N+ +    +      F     D +S++ + F+  LL +N K RL       +   HP+   +D E +  KK+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.0409</Hsp_bit-score>
      <Hsp_score>214</Hsp_score>
      <Hsp_evalue>2.36138e-18</Hsp_evalue>
      <Hsp_query-from>2299</Hsp_query-from>
      <Hsp_query-to>2871</Hsp_query-to>
      <Hsp_hit-from>150</Hsp_hit-from>
      <Hsp_hit-to>337</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>197</Hsp_align-len>
      <Hsp_qseq>ISGGELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQ-----CVEHPWL-QMDTEHMAAKKL</Hsp_qseq>
      <Hsp_hseq>IEGGELFS-LLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENIL-LDRNGH-IKITDFGFAKEVQTVT--WTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYP----PYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDI</Hsp_hseq>
      <Hsp_midline>I GGELF  ++ +           Y  +++  ++++H   I++ DLKPENI+ L++ G+ IKI DFG A++++ V     + GTP+++APEVI  +P   + D WS+GV+ Y +++G +P       +T   +      +          D  D +S L+  ++  R+   Q        HPW  ++  E + AK +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.9669</Hsp_bit-score>
      <Hsp_score>219</Hsp_score>
      <Hsp_evalue>3.02754e-18</Hsp_evalue>
      <Hsp_query-from>2305</Hsp_query-from>
      <Hsp_query-to>2835</Hsp_query-to>
      <Hsp_hit-from>97</Hsp_hit-from>
      <Hsp_hit-to>293</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>200</Hsp_align-len>
      <Hsp_qseq>GGELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLE------------------NVKNLKVMFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFD-DEAFDEISEDSKDFISHLLQK----NMKERLTCTQCVEHPWL</Hsp_qseq>
      <Hsp_hseq>GGELLS-LLHKMGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVL-LDRDG-RLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPFRGENELKTFEKIVALDYPWGPNNRINNSTSPINPLVINLVQKILVIEVNERISLEQIKRHPYF</Hsp_hseq>
      <Hsp_midline>GGEL   ++ +     +     +  Q+++ ++F+H  GI+H DLKPEN++ L++ G R+ I DFG A  ++                  + +N     GT E+V+PE++ Y   GY +D+W++G + Y  V G  P  G+N+ +T   + +  + +  +   +  +      + +L+QK     + ER++  Q   HP+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.1965</Hsp_bit-score>
      <Hsp_score>217</Hsp_score>
      <Hsp_evalue>4.43047e-18</Hsp_evalue>
      <Hsp_query-from>2236</Hsp_query-from>
      <Hsp_query-to>2838</Hsp_query-to>
      <Hsp_hit-from>107</Hsp_hit-from>
      <Hsp_hit-to>314</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>212</Hsp_align-len>
      <Hsp_qseq>LVSPGIVN-----GNCRFVGIGRAIRISGGELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNL-KVMFGTPEFVAPE-VINYEPI-GYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAF---DEISEDSKDFISHLLQKNMKERLTCTQCVEHPWLQ</Hsp_qseq>
      <Hsp_hseq>LSHPNIVKLEEVLQNSRYIGI--VLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLL-LDKNENLV-ITDFGFVNEFCSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGRLYNYINSTPLKFPDYILPIPRDLLRRMLVSDPKKRINLKQIKKHEWLK</Hsp_hseq>
      <Hsp_midline>L  P IV       N R++GI   +  + G  F + I +   L E    +   Q++ GV ++H +G+VH DLK EN++ L++  N + I DFG   +  +   L K   G+P + APE VI+ EP      D+WS GVI Y +++G  P   D +N   +++       +       D I    +D +  +L  + K+R+   Q  +H WL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.0409</Hsp_bit-score>
      <Hsp_score>214</Hsp_score>
      <Hsp_evalue>5.63291e-18</Hsp_evalue>
      <Hsp_query-from>2290</Hsp_query-from>
      <Hsp_query-to>2838</Hsp_query-to>
      <Hsp_hit-from>298</Hsp_hit-from>
      <Hsp_hit-to>489</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>196</Hsp_align-len>
      <Hsp_qseq>AIRISGGE----LFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMF-GTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATW--DFDDEAFDE------ISEDSKDFISHLLQKNMKERLTCTQCVEHPWLQ</Hsp_qseq>
      <Hsp_hseq>AMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNIL-LNENG-QVKLCDFGVSG--EAVNSLATTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANGKFPCSSEKMAANIAPFELLMWILTFTPELKDEPESNIIWSPSFKSFIDYCLKKDSRERPSPRQMINHPWIK</Hsp_hseq>
      <Hsp_midline>A+   GG     +++ +++    ++E+   K    ++ G+ ++H + ++H D+KP+NI+ LN+ G ++K+ DFG++   E V +L   F GT  ++APE I  +P    +D+WS+G+    + +G  P   +     +A      W   F  E  DE       S   K FI + L+K+ +ER +  Q + HPW++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.2705</Hsp_bit-score>
      <Hsp_score>212</Hsp_score>
      <Hsp_evalue>1.49736e-17</Hsp_evalue>
      <Hsp_query-from>2299</Hsp_query-from>
      <Hsp_query-to>2835</Hsp_query-to>
      <Hsp_hit-from>270</Hsp_hit-from>
      <Hsp_hit-to>478</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>211</Hsp_align-len>
      <Hsp_qseq>ISGGELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMC------------LNQTGN--------------------RIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWL</Hsp_qseq>
      <Hsp_hseq>LTGGEIFGEIVRLTY-FSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFS-KNTKTPCGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTMLCGFPPFYDEKIDTLTEKISRGEYTFLKPWWDEISAGAKNAVAKLLELEPSKRYDIDQFLDDPWL</Hsp_hseq>
      <Hsp_midline>++GGE+F  I+   +  +E      ++Q+   V+ MH  G+VH D+KPEN++             L ++ +                     +K+ DFGL++++ + KN K   GT  + APEV+  E      DMW +G + Y ++ G  P   +  +     ++   + F    +DEIS  +K+ ++ LL+    +R    Q ++ PWL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.5001</Hsp_bit-score>
      <Hsp_score>210</Hsp_score>
      <Hsp_evalue>1.73205e-17</Hsp_evalue>
      <Hsp_query-from>2317</Hsp_query-from>
      <Hsp_query-to>2886</Hsp_query-to>
      <Hsp_hit-from>304</Hsp_hit-from>
      <Hsp_hit-to>494</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>201</Hsp_align-len>
      <Hsp_qseq>FERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMF-GTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLA--NVTSATWDFDDEAFDE------ISEDSKDFISHLLQKNMKERLTCTQCVEHPWL--QMDTEHMAAKKLSKERM</Hsp_qseq>
      <Hsp_hseq>YKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNIL-LNEKG-EIKLCDFGVSG--EAVNSLAMTFTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRFPFESDKITQNVAPIELLTMILTFSPQLKDEPELDISWSKTFRSFIDYCLKKDARERPSPRQMLKHPWIVGQM------KKKVNMERF</Hsp_hseq>
      <Hsp_midline>++ ++     ++ER   K    ++ G+ ++H + ++H D+KP+NI+ LN+ G  IK+ DFG++   E V +L + F GT  ++APE I  +P     D+WS+G+    +  G  P   D   + +A   + +    F  +  DE       S+  + FI + L+K+ +ER +  Q ++HPW+  QM       KK++ ER </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.5001</Hsp_bit-score>
      <Hsp_score>210</Hsp_score>
      <Hsp_evalue>1.87754e-17</Hsp_evalue>
      <Hsp_query-from>2305</Hsp_query-from>
      <Hsp_query-to>2835</Hsp_query-to>
      <Hsp_hit-from>100</Hsp_hit-from>
      <Hsp_hit-to>281</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>185</Hsp_align-len>
      <Hsp_qseq>GGELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQ-GIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVK-NLKVMF---GTPEFVAPEVINYEPIGYA--TDMWSVGVICYILVSGLSPL-MGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWL</Hsp_qseq>
      <Hsp_hseq>GGDLFDKI-EPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENIL-LDKNGN-LKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQTPWELPSLENEDFVFFIENDGNLNWGPWSKIEFTHLNLLRKILQPDPNKRVTLKALKLHPWV</Hsp_hseq>
      <Hsp_midline>GG+LF++I + D  +       Y +Q+V  + ++H + G+ H D+KPENI+ L++ GN +K+ DFGLA +       L+V     G+P ++APEV+  E   YA  TD+WS+G++ ++L++G +P  +   +NE          + +   + +I     + +  +LQ +  +R+T      HPW+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.8037</Hsp_bit-score>
      <Hsp_score>203</Hsp_score>
      <Hsp_evalue>2.23469e-16</Hsp_evalue>
      <Hsp_query-from>2317</Hsp_query-from>
      <Hsp_query-to>2838</Hsp_query-to>
      <Hsp_hit-from>211</Hsp_hit-from>
      <Hsp_hit-to>392</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>188</Hsp_align-len>
      <Hsp_qseq>FERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKL----ENVKNLKVMF----------GTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWLQ</Hsp_qseq>
      <Hsp_hseq>FLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILL--DKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKIQYAF-TAGFPQI---VKDLVKKLLVRDPNDRLTIKQIKAHLFFH</Hsp_hseq>
      <Hsp_midline>F  +I +   L E     Y  QI++ V  +H  GI+H D+KPENI+       ++K+ DFG A+ L     N  + K  F          GT E+V+PE++N        D+W+ G I Y +++G  P    N+  T   V    + F    F +I    KD +  LL ++  +RLT  Q   H +  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.1073</Hsp_bit-score>
      <Hsp_score>196</Hsp_score>
      <Hsp_evalue>1.21949e-15</Hsp_evalue>
      <Hsp_query-from>2347</Hsp_query-from>
      <Hsp_query-to>2838</Hsp_query-to>
      <Hsp_hit-from>176</Hsp_hit-from>
      <Hsp_hit-to>338</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>167</Hsp_align-len>
      <Hsp_qseq>LTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMF-GTPEFVAPEVINYEPIGYA--TDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWLQ</Hsp_qseq>
      <Hsp_hseq>LTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFF--DSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRDK--PISDEGKILIRDILSLDPIERPSLTEIMDYVWFR</Hsp_hseq>
      <Hsp_midline>LTE E   +  QI   +++MH + ++H DLK  NI     +   +KI DFGLA  L N    K    GTP ++APEV+  +  G++   D+WS+GV+ Y L+ G  P    + N     +    + F  +    IS++ K  I  +L  +  ER + T+ +++ W +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.4925</Hsp_bit-score>
      <Hsp_score>197</Hsp_score>
      <Hsp_evalue>1.52431e-15</Hsp_evalue>
      <Hsp_query-from>2311</Hsp_query-from>
      <Hsp_query-to>2835</Hsp_query-to>
      <Hsp_hit-from>1191</Hsp_hit-from>
      <Hsp_hit-to>1354</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>176</Hsp_align-len>
      <Hsp_qseq>ELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINYEPI-GYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWL</Hsp_qseq>
      <Hsp_hseq>DLFD-LIEFKTNMTEFEAKLIFKQVVAGIKHLHDQGIVHRDIKDENVIV--DSKGFVKIIDFGSAAYVKS-GPFDVFVGTIDYAAPEVLGGNPYEGQPQDIWAIGILLYTVVFKENPFY--NIDEILEG------DLKFNNAEEVSEDCIELIKSILNRCVPKRPTIDDINNDKWL</Hsp_hseq>
      <Hsp_midline>+LF+ +I+    +TE E     +Q+V G++ +H QGIVH D+K EN++    +   +KIIDFG A  +++     V  GT ++ APEV+   P  G   D+W++G++ Y +V   +P    N +E L        D      +E+SED  + I  +L + + +R T        WL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.9518</Hsp_bit-score>
      <Hsp_score>193</Hsp_score>
      <Hsp_evalue>1.99438e-15</Hsp_evalue>
      <Hsp_query-from>2299</Hsp_query-from>
      <Hsp_query-to>2799</Hsp_query-to>
      <Hsp_hit-from>234</Hsp_hit-from>
      <Hsp_hit-to>406</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>182</Hsp_align-len>
      <Hsp_qseq>ISGGELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKL-----------ENVKNLKVMFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDND----NETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKER</Hsp_qseq>
      <Hsp_hseq>IPGGELFYHL-KEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCL-LNQRGHLV-LTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIPF------YLSEGMKDILNALLKKETAKR</Hsp_hseq>
      <Hsp_midline>I GGELF  +  E   L E     Y  +I   ++F+H +G+V+ DLKPEN + LNQ G+ + + DFGL++K            ENV  L  + GTPE+ APE++  +      D +S+G + Y ++ G  P  G N     N+   N       F       +SE  KD ++ LL+K   +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.337</Hsp_bit-score>
      <Hsp_score>194</Hsp_score>
      <Hsp_evalue>2.99393e-15</Hsp_evalue>
      <Hsp_query-from>2347</Hsp_query-from>
      <Hsp_query-to>2877</Hsp_query-to>
      <Hsp_hit-from>118</Hsp_hit-from>
      <Hsp_hit-to>285</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>180</Hsp_align-len>
      <Hsp_qseq>LTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAF---DEISEDSKDFISHLLQKNMKERLTCTQCVEHPWLQMDTEHMAAKKLSK</Hsp_qseq>
      <Hsp_hseq>LSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILL--SADNTVKLADFGVS-TIVNSSALTLA-GTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNPPY----HNLTDANIYYAV---ENDTYYPPSSFSEPLKDFLSKCFVKNMYKRPTADQLLKHVWIN-STENVKVDKLNK</Hsp_hseq>
      <Hsp_midline>L+E E   Y+ Q + G++++H +G++H D+K  NI+      N +K+ DFG++  + N   L +  GT  ++APE++        +D+WS+G     +++   P      N T AN+  A    +++ +      SE  KDF+S    KNM +R T  Q ++H W+   TE++   KL+K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.337</Hsp_bit-score>
      <Hsp_score>194</Hsp_score>
      <Hsp_evalue>3.12632e-15</Hsp_evalue>
      <Hsp_query-from>2245</Hsp_query-from>
      <Hsp_query-to>2697</Hsp_query-to>
      <Hsp_hit-from>885</Hsp_hit-from>
      <Hsp_hit-to>1036</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>156</Hsp_align-len>
      <Hsp_qseq>PGIVNGNCRFVGIGRAIR----ISGGELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMF-GTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANV</Hsp_qseq>
      <Hsp_hseq>PFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQ--RLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENIL-LTPEGH-IKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAI</Hsp_hseq>
      <Hsp_midline>P + N  C F    R       I GG+L   + ++   L+ R    Y  +++  +++ H  G+++ DLK ENI+ L   G+ IKI D+GL +      N    F GTPEF+APE++  +    A D W+ GV+ Y ++   SP  GD+++E    +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YMR291W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:852630:854390:1 gene:YMR291W transcript:YMR291W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TDA1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000004905]</Hit_def>
  <Hit_accession>YMR291W</Hit_accession>
  <Hit_len>586</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.5666</Hsp_bit-score>
      <Hsp_score>192</Hsp_score>
      <Hsp_evalue>3.34688e-15</Hsp_evalue>
      <Hsp_query-from>2308</Hsp_query-from>
      <Hsp_query-to>2838</Hsp_query-to>
      <Hsp_hit-from>139</Hsp_hit-from>
      <Hsp_hit-to>352</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>214</Hsp_align-len>
      <Hsp_qseq>GELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMC---LNQTGNRIK-----------------IIDFGLARKLEN--VKNLKVMFGTPEFVAPEVINYEPIGYAT--------------DMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAF-DEISEDSKDFISHLLQKNMKERLTCTQCVEHPWLQ</Hsp_qseq>
      <Hsp_hseq>GDLYEKIVENQCLDLETQVTSYCACLVSVLEFLHSQGIVHRDLKAENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLVLADFGLAAEYNTSKVNSLKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGCPVDIWALGVLTYFMAFGYTPFDCTTDDETLECISKCDYYVDEQMMHDPKYEQFWNFVQCCFTIDPAVRRSAKNLKQHPFIK</Hsp_hseq>
      <Hsp_midline>G+L+E+I++      E +   Y   +V  ++F+H QGIVH DLK EN++    +N+    ++                 + DFGLA +     V +LK   GT  ++APE++  + +G  T              D+W++GV+ Y +  G +P     D+ETL  ++   +  D++   D   E   +F+      +   R +     +HP+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.0258</Hsp_bit-score>
      <Hsp_score>188</Hsp_score>
      <Hsp_evalue>1.33977e-14</Hsp_evalue>
      <Hsp_query-from>2347</Hsp_query-from>
      <Hsp_query-to>2841</Hsp_query-to>
      <Hsp_hit-from>665</Hsp_hit-from>
      <Hsp_hit-to>827</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>167</Hsp_align-len>
      <Hsp_qseq>LTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLK-VMFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANV-TSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWLQM</Hsp_qseq>
      <Hsp_hseq>LTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLL--DTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATNGTPKLKHP--ESLSLEIKRFLSVCLCVDVRYRASTEELLHHGFFNM</Hsp_hseq>
      <Hsp_midline>LTE +    +R+  +G++F+H + I+H D+K +N++    T  R+KI DFG   +L + ++ +  M GTP ++APEV+         D+WS+G++   ++ G  P + ++  + L  + T+ T        + +S + K F+S  L  +++ R +  + + H +  M</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.2554</Hsp_bit-score>
      <Hsp_score>186</Hsp_score>
      <Hsp_evalue>1.76574e-14</Hsp_evalue>
      <Hsp_query-from>2299</Hsp_query-from>
      <Hsp_query-to>2937</Hsp_query-to>
      <Hsp_hit-from>427</Hsp_hit-from>
      <Hsp_hit-to>625</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>220</Hsp_align-len>
      <Hsp_qseq>ISGGELFERIIDED-FELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLAR-KLENVKNLKVMFGTPEFVAPEVINYEPIGY--ATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVE---HPWLQMDTEHMAAKKLSKERMKRYLTKRNPKSPPAIND</Hsp_qseq>
      <Hsp_hseq>INGGELFYHLQKEGRFDLSRARF--YTAELLCALDNLHKLDVVYRDLKPENILLDYQ--GHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELL--LGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPD-GFD---RDAKDLLIGLLSRDPTRRLGYNGADEIRNHPFFS----QLSWKRL---LMKGYI----PPYKPAVSN</Hsp_hseq>
      <Hsp_midline>I+GGELF  +  E  F+L+      Y  +++  +  +H+  +V+ DLKPENI+   Q    I + DFGL +  +++        GTPE++APE++    +GY  A D W++GV+ Y +++GL P   ++  +    +      F D  FD    D+KD +  LL ++   RL      E   HP+       ++ K+L    MK Y+    P   PA+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.6406</Hsp_bit-score>
      <Hsp_score>187</Hsp_score>
      <Hsp_evalue>1.91981e-14</Hsp_evalue>
      <Hsp_query-from>2347</Hsp_query-from>
      <Hsp_query-to>2670</Hsp_query-to>
      <Hsp_hit-from>711</Hsp_hit-from>
      <Hsp_hit-to>817</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>110</Hsp_align-len>
      <Hsp_qseq>LTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLK--VMFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGD</Hsp_qseq>
      <Hsp_hseq>LTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNIL-LSMEGD-IKLTDFGFCAQI-NELNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPPYLNE</Hsp_hseq>
      <Hsp_midline>LTE +     R+ + G++F+H +G++H D+K +NI+ L+  G+ IK+ DFG   ++ N  NLK   M GTP ++APEV++ +  G   D+WS+G++   ++ G  P + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.485</Hsp_bit-score>
      <Hsp_score>184</Hsp_score>
      <Hsp_evalue>2.85314e-14</Hsp_evalue>
      <Hsp_query-from>2347</Hsp_query-from>
      <Hsp_query-to>2841</Hsp_query-to>
      <Hsp_hit-from>479</Hsp_hit-from>
      <Hsp_hit-to>641</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>169</Hsp_align-len>
      <Hsp_qseq>LTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKL-ENVKNLKVMFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETL---ANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWLQM</Hsp_qseq>
      <Hsp_hseq>LNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNIL-LNSQG-LVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANNGSPKLRHP----ESVSKQTKQFLDACLQVNVESRASVRKLLTFEFLSM</Hsp_hseq>
      <Hsp_midline>L E +    +++  +G++F+H + I+H D+K +NI+ LN  G  +KI DFG   +L E       M GTP ++APE++N +      D+WS+G++   ++ G  P + ++  + L   AN  S          + +S+ +K F+   LQ N++ R +  + +   +L M</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.485</Hsp_bit-score>
      <Hsp_score>184</Hsp_score>
      <Hsp_evalue>3.85842e-14</Hsp_evalue>
      <Hsp_query-from>2362</Hsp_query-from>
      <Hsp_query-to>2802</Hsp_query-to>
      <Hsp_hit-from>149</Hsp_hit-from>
      <Hsp_hit-to>314</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>166</Hsp_align-len>
      <Hsp_qseq>CIKYMRQIVEGVQFMHRQGIVHLDLKPENIMC------------LNQTGNR-------IKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERL</Hsp_qseq>
      <Hsp_hseq>VLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVVFEMCCGTPPFRASNHLELFKKIKRANDVITFPSYCNIEPELKELICSLLTFDPAQRI</Hsp_hseq>
      <Hsp_midline> + Y++Q+   ++F+  + +VH D+KP+N++              ++ G         +KI DFG AR L N    + + G+P ++APE++NY+      D+WSVG + + +  G  P    N  E    +  A       ++  I  + K+ I  LL  +  +R+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.0998</Hsp_bit-score>
      <Hsp_score>183</Hsp_score>
      <Hsp_evalue>5.91585e-14</Hsp_evalue>
      <Hsp_query-from>2302</Hsp_query-from>
      <Hsp_query-to>2910</Hsp_query-to>
      <Hsp_hit-from>103</Hsp_hit-from>
      <Hsp_hit-to>299</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>212</Hsp_align-len>
      <Hsp_qseq>SGGELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLK--VMFGTPEFVAPEVINYEPIGYAT--DMWSVGVICYILVSGLSPLMGDNDNETLAN----VTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWLQMDTEHMAA-KKLSKERMKRYLTKRN</Hsp_qseq>
      <Hsp_hseq>AGGSL--RSLLRPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNE-GN-VKLCDFGVAAQV-NQTSLRRQTMAGTPYWMAPEVI-MEGVYYDTKVDIWSLGITTYEIATGNPPYC---DVEALRAMQLIIKSKPPRLEDRSY---STSLKEFIALCLDEDPKERLSADDLLKSKFIRA---HKATPTSILKELISRYLLFRD</Hsp_hseq>
      <Hsp_midline>+GG L  R +    ++ E+     MR+++  ++ +H+  ++H D+K  N++  N+ GN +K+ DFG+A ++ N  +L+   M GTP ++APEVI  E + Y T  D+WS+G+  Y + +G  P     D E L      + S     +D ++   S   K+FI+  L ++ KERL+    ++  +++    H A    + KE + RYL  R+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YIL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:287790:288908:-1 gene:YIL035C transcript:YIL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA1 description:Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000001297]</Hit_def>
  <Hit_accession>YIL035C</Hit_accession>
  <Hit_len>372</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.4034</Hsp_bit-score>
      <Hsp_score>176</Hsp_score>
      <Hsp_evalue>1.31357e-13</Hsp_evalue>
      <Hsp_query-from>2257</Hsp_query-from>
      <Hsp_query-to>2835</Hsp_query-to>
      <Hsp_hit-from>128</Hsp_hit-from>
      <Hsp_hit-to>363</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>237</Hsp_align-len>
      <Hsp_qseq>NGNCRFVGIGRAIR--ISG--GELFERIIDEDF-----ELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPE-VINYEPIGYATDMWSVGVICYILVSGLSPLM-GDNDNETLANVTSA--TWDFDD-----------EAFDE-----------ISEDSK---------DFISHLLQKNMKERLTCTQCVEHPWL</Hsp_qseq>
      <Hsp_hseq>NGHANIIHLFDIIKDPISKTPALVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVM-IDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLLKYEITLPREFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWF</Hsp_hseq>
      <Hsp_midline>NG+   + +   I+  IS     +FE + + DF     +LT+ E   YM ++++ + + H  GI+H D+KP N+M ++    ++++ID+GLA          V   +  F  PE +++Y    Y+ D+WS G +   ++    P   G ++ + L  +     T DF+            E +D            I++ +K         D I +LL+ + +ERLT  + + HPW </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.9442</Hsp_bit-score>
      <Hsp_score>180</Hsp_score>
      <Hsp_evalue>1.40327e-13</Hsp_evalue>
      <Hsp_query-from>2311</Hsp_query-from>
      <Hsp_query-to>2841</Hsp_query-to>
      <Hsp_hit-from>936</Hsp_hit-from>
      <Hsp_hit-to>1101</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>180</Hsp_align-len>
      <Hsp_qseq>ELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVI---NYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWLQM</Hsp_qseq>
      <Hsp_hseq>DLFD-VIEFKKDMVEHEAKLVFKQVVASIKHLHDQGIVHRDIKDENVIV--DSHGFVKLIDFGSAAYIKS-GPFDVFVGTMDYAAPEVLGGSSYK--GKPQDIWALGVLLYTIIYKENPYYN------IDEILEGELRFDKS--EHVSEECISLIKRILTREVDKRPTIDEIYEDKWLKI</Hsp_hseq>
      <Hsp_midline>+LF+ +I+   ++ E E     +Q+V  ++ +H QGIVH D+K EN++    +   +K+IDFG A  +++     V  GT ++ APEV+   +Y+  G   D+W++GV+ Y ++   +P         +  +      FD    + +SE+    I  +L + + +R T  +  E  WL++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>1.67094e-13</Hsp_evalue>
      <Hsp_query-from>2299</Hsp_query-from>
      <Hsp_query-to>2838</Hsp_query-to>
      <Hsp_hit-from>424</Hsp_hit-from>
      <Hsp_hit-to>600</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>185</Hsp_align-len>
      <Hsp_qseq>ISGGELFERIIDED-FELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLAR-KLENVKNLKVMFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVE---HPWLQ</Hsp_qseq>
      <Hsp_hseq>INGGELFYHLQHEGRFSLARSRF--YIAELLCALDSLHKLDVIYRDLKPENIL-LDYQGH-IALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPD-GFDPA---AKDLLIGLLSRDPSRRLGVNGTDEIRNHPFFK</Hsp_hseq>
      <Hsp_midline>I+GGELF  +  E  F L       Y+ +++  +  +H+  +++ DLKPENI+ L+  G+ I + DFGL +  +++        GTPE++APE++  +      D W++G++ Y +++GL P   +N       +      F D  FD     +KD +  LL ++   RL      E   HP+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.8626</Hsp_bit-score>
      <Hsp_score>172</Hsp_score>
      <Hsp_evalue>9.30851e-13</Hsp_evalue>
      <Hsp_query-from>2299</Hsp_query-from>
      <Hsp_query-to>2892</Hsp_query-to>
      <Hsp_hit-from>438</Hsp_hit-from>
      <Hsp_hit-to>643</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>214</Hsp_align-len>
      <Hsp_qseq>ISGGELFERIIDEDFEL---TERECIKYMRQIVEGVQFMHRQ-GIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNL-KVMFGTPEFVAPEVI---NYEPIGYA--TDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEA-----FDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWL-QMDTEHMAAKKLSKERMKR</Hsp_qseq>
      <Hsp_hseq>MDGGSL-DKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSANQGT-VKLCDFGVSGNL--VASLAKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPY----PPETYDNIFSQLSAIVDGPPPRLPSDKFSSDAQDFVSLCLQKIPERRPTYAALTEHPWLVKYRNQDVHMSEYITERLER</Hsp_hseq>
      <Hsp_midline>+ GG L ++I DE  E+    E +       ++ G++ +  Q  I+H D+KP NI+C    G  +K+ DFG++  L  V +L K   G   ++APE I   N +   Y   +D+WS+G+    +  G  P       ET  N+ S      D        D+ S D++DF+S  LQK  + R T     EHPWL +   + +   +   ER++R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>1.07603e-12</Hsp_evalue>
      <Hsp_query-from>2371</Hsp_query-from>
      <Hsp_query-to>2835</Hsp_query-to>
      <Hsp_hit-from>1370</Hsp_hit-from>
      <Hsp_hit-to>1558</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>194</Hsp_align-len>
      <Hsp_qseq>YMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLEN-----------------------------VKN----LKVMFGTPEFVAPEVINYEP----IGYATDMWSVGVICYILVSGLSPLMG-DNDNETLANVTSA-TWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWL</Hsp_qseq>
      <Hsp_hseq>YTLQLLEGLAYLHESGIVHRDVKPENIL-LDFNG-VIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLG-ADDVWSLGCVVLEMITGRRPWANLDNEWAIMYHVAAGHTPQFPTK--DEVSSAGMKFLERCLIQNPSKRASAVELLMDPWI</Hsp_hseq>
      <Hsp_midline>Y  Q++EG+ ++H  GIVH D+KPENI+ L+  G  IK +DFG A+K+ N                             VKN    L  M GTP ++APE I        +G A D+WS+G +   +++G  P    DN+   + +V +  T  F  +  DE+S     F+   L +N  +R +  + +  PW+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.5514</Hsp_bit-score>
      <Hsp_score>166</Hsp_score>
      <Hsp_evalue>3.69242e-12</Hsp_evalue>
      <Hsp_query-from>2347</Hsp_query-from>
      <Hsp_query-to>2718</Hsp_query-to>
      <Hsp_hit-from>161</Hsp_hit-from>
      <Hsp_hit-to>295</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>137</Hsp_align-len>
      <Hsp_qseq>LTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLE----NVKN-----LKV-MFGTPEFVAPEVINYE---PIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDF</Hsp_qseq>
      <Hsp_hseq>LTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLI--SSNGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPFNANSGLELFDSIINKPLEF</Hsp_hseq>
      <Hsp_midline>LT ++  K +  +V G++++H QGI H D+KP N++    +   +KI DFG+A        N+++     LK    GTP F APE+ + E       A D+WS+GV  Y L+ G  P   ++  E   ++ +   +F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>4.95289e-12</Hsp_evalue>
      <Hsp_query-from>2347</Hsp_query-from>
      <Hsp_query-to>2697</Hsp_query-to>
      <Hsp_hit-from>113</Hsp_hit-from>
      <Hsp_hit-to>229</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>119</Hsp_align-len>
      <Hsp_qseq>LTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINYEPIGY--ATDMWSVGVICYILVSGLSPLMGDNDNETLANV</Hsp_qseq>
      <Hsp_hseq>LPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANIL-LNEEG-MVKLGDFGVSGHIRSTLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPPLSKYDPMKVMTNL</Hsp_hseq>
      <Hsp_midline>L E +    + ++  G++++H Q  +H D+K  NI+ LN+ G  +K+ DFG++  + +        GTP ++APEV+  E  GY    D+WS+G+  Y L+ GL PL   +  + + N+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>7.97855e-12</Hsp_evalue>
      <Hsp_query-from>2353</Hsp_query-from>
      <Hsp_query-to>2859</Hsp_query-to>
      <Hsp_hit-from>106</Hsp_hit-from>
      <Hsp_hit-to>305</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>202</Hsp_align-len>
      <Hsp_qseq>ERECIKYMR-QIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLE-NVKNLKVMFGTPEFVAPEVI-NYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSK------------------------------DFISHLLQKNMKERLTCTQCVEHPWLQMDTEHMA</Hsp_qseq>
      <Hsp_hseq>ELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLL-INKRG-QLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPKYNPNIQQRPPRDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWFAEYYHHAS</Hsp_hseq>
      <Hsp_midline>E   +KY + Q+++G+ F H   I+H DLKP+N++ +N+ G ++K+ DFGLAR     V        T  + AP+V+        + D+WS G I   +++G     G ND E L  +       ++  +  +++  K                              DF+  LLQ N   RL+  Q + HPW      H +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YKL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:347214:349136:-1 gene:YKL048C transcript:YKL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ELM1 description:Serine/threonine protein kinase; regulates the orientation checkpoint, the morphogenesis checkpoint and the metabolic switch from fermentative to oxidative metabolism by phosphorylating the activation loop of Kin4p, Hsl1p and Snf4p respectively; cooperates with Hsl7p in recruiting Hsl1p to the septin ring, a prerequisite for subsequent recruitment, phosphorylation, and degradation of Swe1p; forms part of the bud neck ring; regulates cytokinesis [Source:SGD;Acc:S000001531]</Hit_def>
  <Hit_accession>YKL048C</Hit_accession>
  <Hit_len>640</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>1.2672e-11</Hsp_evalue>
      <Hsp_query-from>2368</Hsp_query-from>
      <Hsp_query-to>2823</Hsp_query-to>
      <Hsp_hit-from>238</Hsp_hit-from>
      <Hsp_hit-to>404</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>174</Hsp_align-len>
      <Hsp_qseq>KYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLA-----------RKLENV--KNLKVMFGTPEFVAPEVI-------NYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANV--TSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVE</Hsp_qseq>
      <Hsp_hseq>KILEDMTKGLEYLHSQGCIHRDIKPSNIL-LDEEEKVAKLSDFGSCIFTPQSLPFSDANFEDCFQRELNKIVGTPAFIAPELCHLGNSKRDFVTDGFKLDIWSLGVTLYCLLYNELPFFGENEFETYHKIIEVSLSSKINGNTLNDL------VIKRLLEKDVTLRISIQDLVK</Hsp_hseq>
      <Hsp_midline>K +  + +G++++H QG +H D+KP NI+ L++     K+ DFG                E+   + L  + GTP F+APE+        ++   G+  D+WS+GV  Y L+    P  G+N+ ET   +   S +   +    +++       I  LL+K++  R++    V+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YJL165C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:106894:109461:-1 gene:YJL165C transcript:YJL165C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HAL5 description:Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters; HAL5 has a paralog, KKQ8, that arose from the whole genome duplication [Source:SGD;Acc:S000003701]</Hit_def>
  <Hit_accession>YJL165C</Hit_accession>
  <Hit_len>855</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>1.54718e-11</Hsp_evalue>
      <Hsp_query-from>2353</Hsp_query-from>
      <Hsp_query-to>2649</Hsp_query-to>
      <Hsp_hit-from>664</Hsp_hit-from>
      <Hsp_hit-to>765</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>108</Hsp_align-len>
      <Hsp_qseq>ERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMF-----GTPEFVAPEVI----NYEPIGYATDMWSVGVICYILVSG</Hsp_qseq>
      <Hsp_hseq>EADC--FMKQLLNGVQYMHDHGIAHCDLKPENILF--QPNGLLKICDFGTSSVFQTAWEKHVHFQSGAMGSEPYVAPEEFIRDAEYDP--RLVDCWSCGIVYCTMVMG</Hsp_hseq>
      <Hsp_midline>E +C  +M+Q++ GVQ+MH  GI H DLKPENI+   Q    +KI DFG +   +      V F     G+  +VAPE       Y+P     D WS G++   +V G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YPR111W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:747306:749000:1 gene:YPR111W transcript:YPR111W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF20 description:Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006315]</Hit_def>
  <Hit_accession>YPR111W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>1.93952e-11</Hsp_evalue>
      <Hsp_query-from>2371</Hsp_query-from>
      <Hsp_query-to>2697</Hsp_query-to>
      <Hsp_hit-from>272</Hsp_hit-from>
      <Hsp_hit-to>419</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>43</Hsp_gaps>
      <Hsp_align-len>150</Hsp_align-len>
      <Hsp_qseq>YMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLAR-------------KLENVKNLKV----------------------------MFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANV</Hsp_qseq>
      <Hsp_hseq>YISEMFCAVNALHELGYTHRDLKPENFL-IDATGH-IKLTDFGLAAGTVSNERIESMKIRLEEVKNLEFPAFTERSIEDRRKIYHNMRKTEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYENL</Hsp_hseq>
      <Hsp_midline>Y+ ++   V  +H  G  H DLKPEN + ++ TG+ IK+ DFGLA              +LE VKNL+                             M G+P+++A EV+  +   +  D WS+G + +  + G +P  G + NET  N+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>1.98698e-11</Hsp_evalue>
      <Hsp_query-from>2362</Hsp_query-from>
      <Hsp_query-to>2877</Hsp_query-to>
      <Hsp_hit-from>1279</Hsp_hit-from>
      <Hsp_hit-to>1455</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>183</Hsp_align-len>
      <Hsp_qseq>CIKYMR-QIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLK--VMFGTPEFVAPEVINYEPIGYA--TDMWSVGVICYILVSGLSPLMGDNDNETLANV-----TSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWLQMD-TEHMAAKKLSK</Hsp_qseq>
      <Hsp_hseq>LIKHLTTQVLKGLAYLHSKGILHRDMKADNLL-LDQDG-ICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQ-GYSAKVDIWSLGCIVLEMFAGKRPW---SNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANELLSHPFSEVNETFNFKSTRLAK</Hsp_hseq>
      <Hsp_midline> IK++  Q+++G+ ++H +GI+H D+K +N++ L+Q G   KI DFG++RK +++ +     M GT  ++APE+++ +  GY+   D+WS+G I   + +G  P    ++ E +A +     + +     ++    IS+  ++F+    + N ++R T  + + HP+ +++ T +  + +L+K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>2.88178e-11</Hsp_evalue>
      <Hsp_query-from>2371</Hsp_query-from>
      <Hsp_query-to>2835</Hsp_query-to>
      <Hsp_hit-from>1138</Hsp_hit-from>
      <Hsp_hit-to>1310</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>176</Hsp_align-len>
      <Hsp_qseq>YMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKL-----------------ENVKNLKVMFGTPEFVAPEVINYEPIG---YATDMWSVGVICYILVSGLSPLMG-DNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWL</Hsp_qseq>
      <Hsp_hseq>YTFELLEGLAYLHQSGVVHRDIKPENIL-LDFNG-IIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPWSNLDNEWAIMYHVAAGRIP-QLPNRDEMTAAGRAFLERCLVQDPTMRATAVELLIDPWM</Hsp_hseq>
      <Hsp_midline>Y  +++EG+ ++H+ G+VH D+KPENI+ L+  G  IK +DFG AR +                    K+L  M GTP ++APE I+   +     A D+W++G +   + +G  P    DN+   + +V +          DE++   + F+   L ++   R T  + +  PW+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>3.0029e-11</Hsp_evalue>
      <Hsp_query-from>2347</Hsp_query-from>
      <Hsp_query-to>2856</Hsp_query-to>
      <Hsp_hit-from>249</Hsp_hit-from>
      <Hsp_hit-to>455</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>211</Hsp_align-len>
      <Hsp_qseq>LTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKV-----------MFGTPEFVAPEVINYEP-----------------IGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFIS-------------HLLQKNMKERLTCTQCVEHPWLQMDTEHM</Hsp_qseq>
      <Hsp_hseq>LSFQETREILRGVVLGLEYLHYQGIIHRDIKPANLLI--SGDGTVKISDFGVSLAASSTNSSDSSESLDELELAKTVGTPAFFAPEMCLGEDAFTRYNLTKENLFRGSCISFMIDIWAVGVTLYCLLFGMLPFFSDFELKLFEKIVNDPLKF--PTFKEIQSNKVSKVSCEEEYEMAKDLLLKLLEKNPQKRMTIPAIKKHPFVSWDFDHV</Hsp_hseq>
      <Hsp_midline>L+ +E  + +R +V G++++H QGI+H D+KP N++        +KI DFG++    +  +                GTP F APE+   E                  I +  D+W+VGV  Y L+ G+ P   D + +    + +    F    F EI  +    +S              LL+KN ++R+T     +HP++  D +H+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>3.97324e-11</Hsp_evalue>
      <Hsp_query-from>2299</Hsp_query-from>
      <Hsp_query-to>2841</Hsp_query-to>
      <Hsp_hit-from>101</Hsp_hit-from>
      <Hsp_hit-to>320</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>43</Hsp_gaps>
      <Hsp_align-len>222</Hsp_align-len>
      <Hsp_qseq>ISGGELFERIIDEDFE--------LTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARK-----LENVKNLKVMFGTPEFVAPEV-INYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEI-SEDSKDFISHL--------------------------LQKNMKERLTCTQCVEHPWLQM</Hsp_qseq>
      <Hsp_hseq>INGLYLYEELMECDMHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLV--NADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPYLSI</Hsp_hseq>
      <Hsp_midline>I+G  L+E +++ D          LT+     +  QI+ G++++H   ++H DLKP N++       ++KI DFGLAR      +EN + L     T  + APE+ ++Y+    A D+WS G I    + G     G +    L  +        DE    I S++ +D+I  L                          L  + ++R+T  + +EHP+L +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>4.04946e-11</Hsp_evalue>
      <Hsp_query-from>2383</Hsp_query-from>
      <Hsp_query-to>2835</Hsp_query-to>
      <Hsp_hit-from>314</Hsp_hit-from>
      <Hsp_hit-to>466</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>162</Hsp_align-len>
      <Hsp_qseq>IVEGVQFMHRQ-GIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDE----------ISEDSKDFISHLLQKNMKERLTCTQCVEHPWL</Hsp_qseq>
      <Hsp_hseq>VLNGLDHLYRQYKIIHRDIKPSNVL-INSKG-QIKLCDFGVSKKLIN-SIADTFVGTSTYMSPERIQGNVYSIKGDVWSLGLMIIELVTGEFPLGGHND------TPDGILDLLQRIVNEPSPRLPKDRIYSKEMTDFVNRCCIKNERERSSIHELLHHDLI</Hsp_hseq>
      <Hsp_midline>++ G+  ++RQ  I+H D+KP N++ +N  G +IK+ DFG+++KL N        GT  +++PE I         D+WS+G++   LV+G  PL G ND            D      +E           S++  DF++    KN +ER +  + + H  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>4.94114e-11</Hsp_evalue>
      <Hsp_query-from>2314</Hsp_query-from>
      <Hsp_query-to>2664</Hsp_query-to>
      <Hsp_hit-from>796</Hsp_hit-from>
      <Hsp_hit-to>926</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>135</Hsp_align-len>
      <Hsp_qseq>LFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLA----RKLENVK-----------NLKVMFGTPEFVAPEVINYEPIGYAT---DMWSVGVICYILVSGLSPLM</Hsp_qseq>
      <Hsp_hseq>LYDLIHSENLNQQRDEYWRLFRQILEALSYIHSQGIIHRDLKPMNIF-IDESRN-VKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVL--DGTGHYNEKIDMYSLGIIFFEMIYPFSTGM</Hsp_hseq>
      <Hsp_midline>L++ I  E+      E  +  RQI+E + ++H QGI+H DLKP NI  ++++ N +KI DFGLA    R L+ +K           NL    GT  +VA EV+  +  G+     DM+S+G+I + ++   S  M</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>5.4764e-11</Hsp_evalue>
      <Hsp_query-from>2326</Hsp_query-from>
      <Hsp_query-to>2697</Hsp_query-to>
      <Hsp_hit-from>271</Hsp_hit-from>
      <Hsp_hit-to>393</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>128</Hsp_align-len>
      <Hsp_qseq>IIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVI----NYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANV</Hsp_qseq>
      <Hsp_hseq>LLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQ-GN-LKITDFGLARKMNSRADYTNRVITLWYRPPELLLGTTNY---GTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESI</Hsp_hseq>
      <Hsp_midline>+++++ +++  +C    +Q++ G++++H   I+H D+K  NI+  NQ GN +KI DFGLARK+ +  +      T  +  PE++    NY   G   DMW  G +   L +  +   G N+ E + ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>8.90565e-11</Hsp_evalue>
      <Hsp_query-from>2302</Hsp_query-from>
      <Hsp_query-to>2649</Hsp_query-to>
      <Hsp_hit-from>407</Hsp_hit-from>
      <Hsp_hit-to>525</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>123</Hsp_align-len>
      <Hsp_qseq>SGGELFERIIDE-DFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLAR--KLENVKNLKV---MFGTPEFVAP-EVINYEPIGYATDMWSVGVICYILVSG</Hsp_qseq>
      <Hsp_hseq>AGGDLFTLVVAAGKLEYMEADC--FFKQLIRGVVYMHEMGVCHRDLKPENLL-LTHDG-VLKITDFGNSECFKMAWEKNIHLSGGVCGSSPYIAPEEYIKEEFDPRPVDIWACGVIYMAMRTG</Hsp_hseq>
      <Hsp_midline>+GG+LF  ++     E  E +C  + +Q++ GV +MH  G+ H DLKPEN++ L   G  +KI DFG +   K+   KN+ +   + G+  ++AP E I  E      D+W+ GVI   + +G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>8.94606e-11</Hsp_evalue>
      <Hsp_query-from>2353</Hsp_query-from>
      <Hsp_query-to>2835</Hsp_query-to>
      <Hsp_hit-from>553</Hsp_hit-from>
      <Hsp_hit-to>712</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>166</Hsp_align-len>
      <Hsp_qseq>ERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLE--NVKNLK--VMFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANV-TSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWL</Hsp_qseq>
      <Hsp_hseq>ESLITNFTRQILIGVAYLHKKNIIHRDIKGANILI--DIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKIGTNTTPEIPSWATSE----GKNFLRKAFELDYQYRPSALELLQHPWL</Hsp_hseq>
      <Hsp_midline>E     + RQI+ GV ++H++ I+H D+K  NI+        +KI DFG+++KL   N K  K   + G+  +++PEV+         D+WS G +   + +G  P    +  + +  + T+ T +    A  E     K+F+    + + + R +  + ++HPWL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>9.01197e-11</Hsp_evalue>
      <Hsp_query-from>2323</Hsp_query-from>
      <Hsp_query-to>2838</Hsp_query-to>
      <Hsp_hit-from>130</Hsp_hit-from>
      <Hsp_hit-to>338</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>51</Hsp_gaps>
      <Hsp_align-len>216</Hsp_align-len>
      <Hsp_qseq>RIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINY---------------EPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANV----------------TSATWDFDDEA-------------FDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWLQ</Hsp_qseq>
      <Hsp_hseq>KVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILC--TLNGCLKICDFGLARGIH-----AGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDKDILIKFGTIKAWNLGKNSNNPVYKKIPWSNIFPFASHEAINLIESLLHWDSTHRLNVEQAISHPFLN</Hsp_hseq>
      <Hsp_midline>++I    +L+E     ++ QI+ G++++H   ++H DLKP NI+C       +KI DFGLAR +         F     V P + NY               +P   + D+W+VG I     +     MG +    +  +                T   W+    +             F   S ++ + I  LL  +   RL   Q + HP+L </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>9.82227e-11</Hsp_evalue>
      <Hsp_query-from>2305</Hsp_query-from>
      <Hsp_query-to>2661</Hsp_query-to>
      <Hsp_hit-from>312</Hsp_hit-from>
      <Hsp_hit-to>445</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>134</Hsp_align-len>
      <Hsp_qseq>GGELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMC------LNQ--------TGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINYEPI-GYATDMWSVGVICYILVSGLSPL</Hsp_qseq>
      <Hsp_hseq>AGDLLAAVMARNGRLEAWLIQRIFTEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLCKKIENNEMCTARCGSEDYVSPEILMGVPYDGHLSDTWALGVILYSLFEDRLPF</Hsp_hseq>
      <Hsp_midline> G+L   ++  +  L      +   ++V  V+++H   I+H DLK ENI+       +N           N I++ DFGL +K+EN +      G+ ++V+PE++   P  G+ +D W++GVI Y L     P </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>1.94853e-10</Hsp_evalue>
      <Hsp_query-from>2353</Hsp_query-from>
      <Hsp_query-to>2832</Hsp_query-to>
      <Hsp_hit-from>117</Hsp_hit-from>
      <Hsp_hit-to>301</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>189</Hsp_align-len>
      <Hsp_qseq>ERECIKY-MRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEV-INYEPIGYATDMWSVGVICYILVSG---------------LSPLMGDNDNETLANVTSA-TWDF-----------DDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPW</Hsp_qseq>
      <Hsp_hseq>EKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNIL-INENCD-LKICDFGLARIQD--PQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENTLKFVTSLPHRDPIPFSERFKTVEPDAVDLLEKMLVFDPKKRITAADALAHPY</Hsp_hseq>
      <Hsp_midline>E++ ++Y + QI+ G++++H  G++H DLKP NI+ +N+  + +KI DFGLAR  +    +     T  + APE+ + ++      D+WS G I   ++ G               ++ L+G    + +  + S  T  F             E F  +  D+ D +  +L  + K+R+T    + HP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YKL198C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:68232:70220:-1 gene:YKL198C transcript:YKL198C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK1 description:Putative serine/threonine protein kinase; regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein; PTK1 has a paralog, PTK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001681]</Hit_def>
  <Hit_accession>YKL198C</Hit_accession>
  <Hit_len>662</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>2.7213e-10</Hsp_evalue>
      <Hsp_query-from>2278</Hsp_query-from>
      <Hsp_query-to>2664</Hsp_query-to>
      <Hsp_hit-from>277</Hsp_hit-from>
      <Hsp_hit-to>424</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>152</Hsp_align-len>
      <Hsp_qseq>GIGRAIRISGGELFERIIDEDFE---LTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLEN--------VKNLKVMFGTPEFVAPEVINYEPIGY------------ATDMWSVGVICYILVSGLSPLM</Hsp_qseq>
      <Hsp_hseq>GWGFVMELGLRDLFAMIQKSGWRSVALAEKFCI--FKQVACGVKFCHDQGIAHRDLKPENVL-LSPDG-VCKLTDFGISDWYHTDPHDLSSPVKKCAGMIGSPPYAPPEVMFYDSKKHYDTELQQPYDPRALDCYGLGIILMTLVNNVIPFL</Hsp_hseq>
      <Hsp_midline>G G  + +   +LF  I    +    L E+ CI   +Q+  GV+F H QGI H DLKPEN++ L+  G   K+ DFG++             VK    M G+P +  PEV+ Y+   +            A D + +G+I   LV+ + P +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YKL168C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:131288:133462:-1 gene:YKL168C transcript:YKL168C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KKQ8 description:Putative serine/threonine protein kinase with unknown cellular role; KKQ8 has a paralog, HAL5, that arose from the whole genome duplication [Source:SGD;Acc:S000001651]</Hit_def>
  <Hit_accession>YKL168C</Hit_accession>
  <Hit_len>724</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>2.91664e-10</Hsp_evalue>
      <Hsp_query-from>2353</Hsp_query-from>
      <Hsp_query-to>2649</Hsp_query-to>
      <Hsp_hit-from>539</Hsp_hit-from>
      <Hsp_hit-to>640</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>108</Hsp_align-len>
      <Hsp_qseq>ERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLEN-----VKNLKVMFGTPEFVAPEVI----NYEPIGYATDMWSVGVICYILVSG</Hsp_qseq>
      <Hsp_hseq>EADC--FMKQLLHGVKFMHDHGIAHCDLKPENILFYPH--GLLKICDFGTSSVFQTAWERRVHAQKGIIGSEPYVAPEEFVDGEYYDP--RLIDCWSCGVVYITMILG</Hsp_hseq>
      <Hsp_midline>E +C  +M+Q++ GV+FMH  GI H DLKPENI+        +KI DFG +   +      V   K + G+  +VAPE       Y+P     D WS GV+   ++ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YDL028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:400997:403291:-1 gene:YDL028C transcript:YDL028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MPS1 description:Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]</Hit_def>
  <Hit_accession>YDL028C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>3.49632e-10</Hsp_evalue>
      <Hsp_query-from>2371</Hsp_query-from>
      <Hsp_query-to>2658</Hsp_query-to>
      <Hsp_hit-from>543</Hsp_hit-from>
      <Hsp_hit-to>653</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>114</Hsp_align-len>
      <Hsp_qseq>YMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKL-ENVKNL--KVMFGTPEFVAPEVI---NYE------------PIGYATDMWSVGVICYILVSGLSP</Hsp_qseq>
      <Hsp_hseq>YTKEMLLCIKVVHDAGIVHSDLKPANFVLVKGI---LKIIDFGIANAVPEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYGKPP</Hsp_hseq>
      <Hsp_midline>Y ++++  ++ +H  GIVH DLKP N + +      +KIIDFG+A  + E+  N+  +   GTP ++APE +   NY              +G  +DMWS G I Y ++ G  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>3.83511e-10</Hsp_evalue>
      <Hsp_query-from>2326</Hsp_query-from>
      <Hsp_query-to>2838</Hsp_query-to>
      <Hsp_hit-from>94</Hsp_hit-from>
      <Hsp_hit-to>291</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>200</Hsp_align-len>
      <Hsp_qseq>IIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKN-LKVMFGTPEFVAPEVI-NYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNE-------TLANVTSATW--------------------DFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWLQ</Hsp_qseq>
      <Hsp_hseq>IKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNL--LFSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDRDWPEVSSFMTYNKLQIYPPPSRDELRKRFIAASEYALDFMCGMLTMNPQKRWTAVQCLESDYFK</Hsp_hseq>
      <Hsp_midline>I D+    T  +   +M   + GV   HR  I+H DLKP N+  L     +IK+ DFGLAR +      L     T  + APE++   +    A D+WSVGVI   L+  +  L G ND +        L   T   W                    D   + F   SE + DF+  +L  N ++R T  QC+E  + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YOR061W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:441534:442553:1 gene:YOR061W transcript:YOR061W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA2 description:Alpha&apos; catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000005587]</Hit_def>
  <Hit_accession>YOR061W</Hit_accession>
  <Hit_len>339</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>6.1556e-10</Hsp_evalue>
      <Hsp_query-from>2314</Hsp_query-from>
      <Hsp_query-to>2850</Hsp_query-to>
      <Hsp_hit-from>123</Hsp_hit-from>
      <Hsp_hit-to>339</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>218</Hsp_align-len>
      <Hsp_qseq>LFERIIDEDFE-----LTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPE-VINYEPIGYATDMWSVGVICYILVSGLSPLM-GDNDNETLANVTSATW------------------------DFDDEAFDE-ISEDSK-------DFISHLLQKNMKERLTCTQCVEHPWLQMDTE</Hsp_qseq>
      <Hsp_hseq>IFEEIKNVDFRTLYPTFKLPDIQYYFTQLLIALDYCHSMGIMHRDVKPQNVM-IDPTERKLRLIDWGLAEFYHPGVDYNVRVASRYHKGPELLVNLNQYDYSLDLWSVGCMLAAIVFKKEPFFKGSSNPDQLVKIATVLGTKELLGYLGKYGLHLPSEYDNIMRDFTKKSWTHFITSETKLAVPEVVDLIDNLLRYDHQERLTAKEAMDHKFFKTKFE</Hsp_hseq>
      <Hsp_midline>+FE I + DF          +   Y  Q++  + + H  GI+H D+KP+N+M ++ T  ++++ID+GLA       +  V   +     PE ++N     Y+ D+WSVG +   +V    P   G ++ + L  + +                           DF  +++   I+ ++K       D I +LL+ + +ERLT  + ++H + +   E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>6.44061e-10</Hsp_evalue>
      <Hsp_query-from>2371</Hsp_query-from>
      <Hsp_query-to>2697</Hsp_query-to>
      <Hsp_hit-from>153</Hsp_hit-from>
      <Hsp_hit-to>261</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>110</Hsp_align-len>
      <Hsp_qseq>YMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPE-VINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANV</Hsp_qseq>
      <Hsp_hseq>YTFQILRALLTLHSMSICHGDLKPSNILIIPSSG-IAKVCDFGSAQRLDDNTELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPLFKGDSANSQLEEI</Hsp_hseq>
      <Hsp_midline>Y  QI+  +  +H   I H DLKP NI+ +  +G   K+ DFG A++L++   LK  F +  + APE ++N +      D+WS+G I   ++ G     GD+ N  L  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>71</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>7.00051e-10</Hsp_evalue>
      <Hsp_query-from>2374</Hsp_query-from>
      <Hsp_query-to>2664</Hsp_query-to>
      <Hsp_hit-from>267</Hsp_hit-from>
      <Hsp_hit-to>365</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>107</Hsp_align-len>
      <Hsp_qseq>MRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFV------APEVI----NYEPIGYATDMWSVGVICYILVSGLSPLM</Hsp_qseq>
      <Hsp_hseq>MWQLLDGVSYLHQNWVLHRDLKPANIMV--TIDGCVKIGDLGLARKFHNM--LQTLYTGDKVVVTIWYRAPELLLGARHYTP---AVDLWSVGCIFAELI-GLQPIF</Hsp_hseq>
      <Hsp_midline>M Q+++GV ++H+  ++H DLKP NIM        +KI D GLARK  N+  L+ ++   + V      APE++    +Y P   A D+WSVG I   L+ GL P+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>72</Hit_num>
  <Hit_id>YJR059W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:545787:548243:1 gene:YJR059W transcript:YJR059W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK2 description:Serine/threonine protein kinase; involved in regulation of ion transport across plasma membrane; carboxyl terminus is essential for glucose-dependent Pma1p activation via phosphorylation of Pma1p-Ser899; enhances spermine uptake; PTK2 has a paralog, PTK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003820]</Hit_def>
  <Hit_accession>YJR059W</Hit_accession>
  <Hit_len>818</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>2.06255e-09</Hsp_evalue>
      <Hsp_query-from>2311</Hsp_query-from>
      <Hsp_query-to>2664</Hsp_query-to>
      <Hsp_hit-from>350</Hsp_hit-from>
      <Hsp_hit-to>483</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>138</Hsp_align-len>
      <Hsp_qseq>ELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLA--------RKLENVKNLKVMFGTPEFVAPEVINYEPIGY------------ATDMWSVGVICYILVSGLSPLM</Hsp_qseq>
      <Hsp_hseq>QLMERTGWKNVPFNEKYCL--FKQVAQGIKFCHDNGIAHRDLKPENVL-ISKEG-ICKLTDFGISDWYHVIPHDYTSPVKTCQGMIGSPPYTPPEVMYFDAKKHYPEKFQKPYNPLAMDSYALGIMLITMINNIIPFI</Hsp_hseq>
      <Hsp_midline>+L ER   ++    E+ C+   +Q+ +G++F H  GI H DLKPEN++ +++ G   K+ DFG++             VK  + M G+P +  PEV+ ++   +            A D +++G++   +++ + P +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>73</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>3.78796e-09</Hsp_evalue>
      <Hsp_query-from>2302</Hsp_query-from>
      <Hsp_query-to>2661</Hsp_query-to>
      <Hsp_hit-from>164</Hsp_hit-from>
      <Hsp_hit-to>289</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>129</Hsp_align-len>
      <Hsp_qseq>SGGELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINY--------EPIGYA-TDMWSVGVICYILVSGLSPL</Hsp_qseq>
      <Hsp_hseq>SGGDLYEAIKADAVPKKTKSITHIITQIMDAIEYVHNKGIYHRDIKPENIL-ISGIDWTIKLTDWGLATTDKTSMDRNV--GSERYMSPELFDSNLDIKERKEPYDCAKVDLWAMGIVFLNIVFHKNPF</Hsp_hseq>
      <Hsp_midline>SGG+L+E I  +      +     + QI++ ++++H +GI H D+KPENI+ ++     IK+ D+GLA   +   +  V  G+  +++PE+ +         EP   A  D+W++G++   +V   +P </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>74</Hit_num>
  <Hit_id>YOR267C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:822588:824867:-1 gene:YOR267C transcript:YOR267C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRK1 description:Protein kinase; implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005793]</Hit_def>
  <Hit_accession>YOR267C</Hit_accession>
  <Hit_len>759</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>4.67237e-09</Hsp_evalue>
      <Hsp_query-from>2374</Hsp_query-from>
      <Hsp_query-to>2640</Hsp_query-to>
      <Hsp_hit-from>321</Hsp_hit-from>
      <Hsp_hit-to>416</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>100</Hsp_align-len>
      <Hsp_qseq>MRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKL-----ENVKNLKVMFGTPEFVAPEVI----NYEPIGYATDMWSVGVI--CYIL</Hsp_qseq>
      <Hsp_hseq>LKQLTEGVKYLHSMGLAHRDLKLDN--CVMTSQGILKLIDFGSAVVFRYPFEDGVTMAHGIVGSDPYLAPEVITSTKSYDP--QCVDIWSIGIIYCCMVL</Hsp_hseq>
      <Hsp_midline>++Q+ EGV+++H  G+ H DLK +N  C+  +   +K+IDFG A        + V     + G+  ++APEVI    +Y+P     D+WS+G+I  C +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>75</Hit_num>
  <Hit_id>YFL029C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:78055:79161:-1 gene:YFL029C transcript:YFL029C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CAK1 description:Cyclin-dependent kinase-activating kinase; required for passage through the cell cycle; phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases [Source:SGD;Acc:S000001865]</Hit_def>
  <Hit_accession>YFL029C</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>5.21636e-09</Hsp_evalue>
      <Hsp_query-from>2350</Hsp_query-from>
      <Hsp_query-to>2628</Hsp_query-to>
      <Hsp_hit-from>129</Hsp_hit-from>
      <Hsp_hit-to>233</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>105</Hsp_align-len>
      <Hsp_qseq>TERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGN---RIKIIDFGLARKLEN--------VKNLKVMFGTPEFVAPEVI-NYEPIGYATDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>VNRYSLSFFRQMVEGIAFLHENKIIHRDIKPQNIMLTNNTSTVSPKLYIIDFGISYDMANNSQTSAEPMDSKVTDISTGIYKAPEVLFGVKCYDGGVDVWSLLII</Hsp_hseq>
      <Hsp_midline>  R  + + RQ+VEG+ F+H   I+H D+KP+NIM  N T     ++ IIDFG++  + N        + +      T  + APEV+   +      D+WS+ +I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>76</Hit_num>
  <Hit_id>YDL025C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:405344:407206:-1 gene:YDL025C transcript:YDL025C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RTK1 description:Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002183]</Hit_def>
  <Hit_accession>YDL025C</Hit_accession>
  <Hit_len>620</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>6.60538e-09</Hsp_evalue>
      <Hsp_query-from>2347</Hsp_query-from>
      <Hsp_query-to>2835</Hsp_query-to>
      <Hsp_hit-from>402</Hsp_hit-from>
      <Hsp_hit-to>575</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>178</Hsp_align-len>
      <Hsp_qseq>LTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLE-----NVKNLKVMFGTPEFVAPEVI---NYEPIGYATDMWSVGVICYILVSGLSPLMGDNDN-ETLANVTSATWDFDD------EAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWL</Hsp_qseq>
      <Hsp_hseq>MTQDEVNCYFKQLCHGVNYLHSMGLAHRDLKLDN--CVVTKDGILKLIDFGSAVVFQYPYEDTIVKSHGIVGSDPYLAPELLKQTSYDP--RVADVWSIAIIFYCMVLKRFPWKAPKKSFNSFRLFTEEPEDEDDIVRGPNKILRLLPRHSRTIIGRMLALEPKQRVLMNDVVKDDWL</Hsp_hseq>
      <Hsp_midline>+T+ E   Y +Q+  GV ++H  G+ H DLK +N  C+      +K+IDFG A   +      +     + G+  ++APE++   +Y+P     D+WS+ +I Y +V    P      +  +    T    D DD      +    +   S+  I  +L    K+R+     V+  WL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>77</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>1.53708e-08</Hsp_evalue>
      <Hsp_query-from>2314</Hsp_query-from>
      <Hsp_query-to>2697</Hsp_query-to>
      <Hsp_hit-from>456</Hsp_hit-from>
      <Hsp_hit-to>582</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>129</Hsp_align-len>
      <Hsp_qseq>LFERIIDEDFELTERECIK-YMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANV</Hsp_qseq>
      <Hsp_hseq>LYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPELKIIDFG--SSCEEARTVYTYIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAELFLGIPIFPGASEYNQLTRI</Hsp_hseq>
      <Hsp_midline>L+E +    F     + I+ +  QI++ +  +    ++H DLKPENI+        +KIIDFG     E  + +     +  + APE+I   P   + DMWS+G I   L  G+    G ++   L  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>78</Hit_num>
  <Hit_id>YHR079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:258244:261591:-1 gene:YHR079C transcript:YHR079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IRE1 description:Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; role in homeostatic adaptation to ER stress; Kar2p binds inactive Ire1p and releases from it upon ER stress [Source:SGD;Acc:S000001121]</Hit_def>
  <Hit_accession>YHR079C</Hit_accession>
  <Hit_len>1115</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>1.90284e-08</Hsp_evalue>
      <Hsp_query-from>2320</Hsp_query-from>
      <Hsp_query-to>2835</Hsp_query-to>
      <Hsp_hit-from>759</Hsp_hit-from>
      <Hsp_hit-to>980</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>54</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>ERIIDEDFEL-TERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLN--------QTGN---RIKIIDFGLARKLENVK-----NLKVMFGTPEFVAPEVIN--------------------------YEP-----IGYATDMWSVG-VICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAF---DEISEDSKDFISHLLQKNMKERLTCTQCVEHPWL</Hsp_qseq>
      <Hsp_hseq>KNVSDENLKLQKEYNPISLLRQIASGVAHLHSLKIIHRDLKPQNILVSTSSRFTADQQTGAENLRILISDFGLCKKLDSGQSSFRTNLNNPSGTSGWRAPELLEESNNLQCQVETEHSSSRHTVVSSDSFYDPFTKRRLTRSIDIFSMGCVFYYILSKGKHPF-GDKYSRE-SNIIRGIFSLDEMKCLHDRSLIAEATDLISQMIDHDPLKRPTAMKVLRHPLF</Hsp_hseq>
      <Hsp_midline>+ + DE+ +L  E   I  +RQI  GV  +H   I+H DLKP+NI+           QTG    RI I DFGL +KL++ +     NL    GT  + APE++                           Y+P     +  + D++S+G V  YIL  G  P  GD  +   +N+    +  D+        +  ++ D IS ++  +  +R T  + + HP  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>79</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>1.92597e-08</Hsp_evalue>
      <Hsp_query-from>2299</Hsp_query-from>
      <Hsp_query-to>2841</Hsp_query-to>
      <Hsp_hit-from>101</Hsp_hit-from>
      <Hsp_hit-to>320</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>223</Hsp_align-len>
      <Hsp_qseq>ISGGELFERIIDEDFE--------LTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKL-ENVK----NLKVMFGTPEFVAPEV-INYEPIGYATDMWSVGVICYILVSGLSPLMGDND----------------NETLANVTS-----ATWDFDD---EAFDEI----SEDSKDFISHLLQKNMKERLTCTQCVEHPWLQM</Hsp_qseq>
      <Hsp_hseq>LNGVYLYEELMECDLSQIIRSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLV--NSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELL-GRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIPGRSFESILPGANPEALELLKKMLEFDPKKRITVEDALEHPYLSM</Hsp_hseq>
      <Hsp_midline>++G  L+E +++ D          L +     ++ QI+  ++++H   ++H DLKP+N++    +  ++KI +FGL+    EN K     +K    +  + APE+ +NY+    A D+WS G I   L+ G  P+    D                 ETL  + S       + F +    +F+ I    + ++ + +  +L+ + K+R+T    +EHP+L M</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>80</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>2.09298e-08</Hsp_evalue>
      <Hsp_query-from>2347</Hsp_query-from>
      <Hsp_query-to>2841</Hsp_query-to>
      <Hsp_hit-from>115</Hsp_hit-from>
      <Hsp_hit-to>315</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>203</Hsp_align-len>
      <Hsp_qseq>LTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLEN--------VKNLKVMFGTPEFVAPEV-INYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEI-SEDSKDFISHL----------------------------LQKNMKERLTCTQCVEHPWLQM</Hsp_qseq>
      <Hsp_hseq>LSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLL-LNSNCD-LKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIANLPMRPPLPWETVWSKTDLNPDMIDLLDKMLQFNPDKRISAAEALRHPYLAM</Hsp_hseq>
      <Hsp_midline>L++     +  QI+  ++ +H   ++H D+KP N++ LN   + +K+ DFGLAR L +        V  +     T  + APE+ + ++    A D+WS G I   +VSG     G + +  L  +         E F++I S+ +K++I++L                            LQ N  +R++  + + HP+L M</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>81</Hit_num>
  <Hit_id>YDL214C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:74446:76545:-1 gene:YDL214C transcript:YDL214C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR2 description:Serine/threonine protein kinase; inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance; PRR2 has a paralog, NPR1, that arose from the whole genome duplication [Source:SGD;Acc:S000002373]</Hit_def>
  <Hit_accession>YDL214C</Hit_accession>
  <Hit_len>699</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>2.80537e-08</Hsp_evalue>
      <Hsp_query-from>2311</Hsp_query-from>
      <Hsp_query-to>2658</Hsp_query-to>
      <Hsp_hit-from>446</Hsp_hit-from>
      <Hsp_hit-to>563</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>124</Hsp_align-len>
      <Hsp_qseq>ELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLE-----NVKNLKVMFGTPEFVAPEVI---NYEPIGYATDMWSVGVICYILVSGLSP</Hsp_qseq>
      <Hsp_hseq>DLFSLVMSEKMHYEEICCL--FKQLINGVKYLHDIGLSHRDLKLDN--CVVTRRGILKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFYFNEYDP--RALDVWSVGIIFFCMITRRFP</Hsp_hseq>
      <Hsp_midline>+LF  ++ E     E  C+   +Q++ GV+++H  G+ H DLK +N  C+      +K+IDFG +          +     + G+  +++PEV     Y+P   A D+WSVG+I + +++   P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>82</Hit_num>
  <Hit_id>YJL057C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:328118:330121:-1 gene:YJL057C transcript:YJL057C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IKS1 description:Protein kinase of unknown cellular role; putative serine/threonine kinase; expression is induced during mild heat stress; deletion mutants are hypersensitive to copper sulphate and resistant to sorbate; interacts with an N-terminal fragment of Sst2p [Source:SGD;Acc:S000003593]</Hit_def>
  <Hit_accession>YJL057C</Hit_accession>
  <Hit_len>667</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>8.23687e-08</Hsp_evalue>
      <Hsp_query-from>2347</Hsp_query-from>
      <Hsp_query-to>2898</Hsp_query-to>
      <Hsp_hit-from>322</Hsp_hit-from>
      <Hsp_hit-to>548</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>230</Hsp_align-len>
      <Hsp_qseq>LTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCL------NQTGN-------------RIKIIDFGLARKLENVKNLKV-MFGTPEFVAPEVI-----------------NYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSK---------DFISHLLQKNMKERLTCTQCVEHPWLQMDTEHMAAKKLSKERMKRYL</Hsp_qseq>
      <Hsp_hseq>LSTEQLVSIIRDIARGLHELHSIGLIHRDLKPSNCLLLTPFKSDNENDNVYDREHNSDEFFPSIVIGDLG-ESQLEGESRLGTGCTGTLEFTAPDLIIQGRPVSSSTLPSRSSHTYNEYTFASDMYSLGMICYFIVFGELPFEPQLDIVDLK-VRIKNFRFDTEGMIEKHQAMKLKPIDRRIFHLMDALLQPNNDARPTA-KTVEETLDEMLINSKPGKKFWKENVDSTL</Hsp_hseq>
      <Hsp_midline>L+  + +  +R I  G+  +H  G++H DLKP N + L      N+  N              I I D G   +LE    L     GT EF AP++I                  Y    +A+DM+S+G+ICY +V G  P     D   L  V    + FD E   E  +  K           +  LLQ N   R T  + VE    +M       KK  KE +   L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>83</Hit_num>
  <Hit_id>YDR247W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:956013:957398:1 gene:YDR247W transcript:YDR247W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VHS1 description:Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; VHS1 has a paralog, SKS1, that arose from the whole genome duplication [Source:SGD;Acc:S000002655]</Hit_def>
  <Hit_accession>YDR247W</Hit_accession>
  <Hit_len>461</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>8.23935e-08</Hsp_evalue>
      <Hsp_query-from>2311</Hsp_query-from>
      <Hsp_query-to>2823</Hsp_query-to>
      <Hsp_hit-from>144</Hsp_hit-from>
      <Hsp_hit-to>328</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>191</Hsp_align-len>
      <Hsp_qseq>ELFERIIDEDFELTERECIK-YMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINYE-----------PIGYAT-----DMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEI---SEDSKDFISHLLQKNMKERLTCTQCVE</Hsp_qseq>
      <Hsp_hseq>DLFTSIVDNRHFVTNGLLVKKVFLQICSALNYCHEHGIYHCDIKPENLLL--DTEDNVFLCDFGLSTTSTYIKP-NVCIGSSYYMPPERISFDGRVSSSKSGGHKLGKVCPSCNGDLWSLGIILINLTCIRNPWLKADKTE---DNTYYYFTKDPNILKQILPLSDDFYSLLSKILQVNPKNRMSLQELMK</Hsp_hseq>
      <Hsp_midline>+LF  I+D    +T    +K    QI   + + H  GI H D+KPEN++    T + + + DFGL+     +K   V  G+  ++ PE I+++            +G        D+WS+G+I   L    +P +  +  E   + T   +  D     +I   S+D    +S +LQ N K R++  + ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>84</Hit_num>
  <Hit_id>YNL183C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:293137:295509:-1 gene:YNL183C transcript:YNL183C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NPR1 description:Protein kinase; stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p; negatively regulates Ldb19p-mediated endocytosis through phosphorylation of Ldb19p, which prevents its association with the plasma membrane; Npr1p activity is negatively regulated via phosphorylation by the TOR complex; NPR1 has a paralog, PRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005127]</Hit_def>
  <Hit_accession>YNL183C</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>8.5566e-08</Hsp_evalue>
      <Hsp_query-from>2311</Hsp_query-from>
      <Hsp_query-to>2640</Hsp_query-to>
      <Hsp_hit-from>523</Hsp_hit-from>
      <Hsp_hit-to>636</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>120</Hsp_align-len>
      <Hsp_qseq>ELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKL-----ENVKNLKVMFGTPEFVAPEV---INYEPIGYATDMWSVGVI--CYIL</Hsp_qseq>
      <Hsp_hseq>DLFAIVMSNKMSYEEICCC--FKQILTGVQYLHSIGLAHRDLKLDNCV-INEKG-IVKLIDFGAAVVFSYPFSKNLVEASGIVGSDPYLAPEVCIFAKYDP--RPVDIWSSAIIFACMIL</Hsp_hseq>
      <Hsp_midline>+LF  ++       E  C    +QI+ GVQ++H  G+ H DLK +N + +N+ G  +K+IDFG A        +N+     + G+  ++APEV     Y+P     D+WS  +I  C IL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>85</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>1.28155e-07</Hsp_evalue>
      <Hsp_query-from>2308</Hsp_query-from>
      <Hsp_query-to>2679</Hsp_query-to>
      <Hsp_hit-from>537</Hsp_hit-from>
      <Hsp_hit-to>657</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>125</Hsp_align-len>
      <Hsp_qseq>GELFERIIDEDFELTERECIKYMRQIVEGVQFMHRQ-GIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDN</Hsp_qseq>
      <Hsp_hseq>GFLQEQVIAKKKRLEDWRIWKIIVELSLALRFIHDSCHIVHLDLKPANVMITFE-GN-LKLGDFGMATHLPLEDKSFENEGDREYIAPEIISDCTYDYKADIFSLGLMIVEIAANV--VLPDNGN</Hsp_hseq>
      <Hsp_midline>G L E++I +   L +    K + ++   ++F+H    IVHLDLKP N+M   + GN +K+ DFG+A  L          G  E++APE+I+     Y  D++S+G++   + + +  ++ DN N</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>86</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>1.37631e-07</Hsp_evalue>
      <Hsp_query-from>2323</Hsp_query-from>
      <Hsp_query-to>2667</Hsp_query-to>
      <Hsp_hit-from>128</Hsp_hit-from>
      <Hsp_hit-to>242</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>120</Hsp_align-len>
      <Hsp_qseq>RIIDEDFELTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINYEPIG---YAT--DMWSVGVICYILVSGLSPLMG</Hsp_qseq>
      <Hsp_hseq>RYVTNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETG-VLKICDFGSAKKLEHNQPSISYICSRFYRAPELI----IGCTQYTTQIDIWGLGCVMGEMLIGKAIFQG</Hsp_hseq>
      <Hsp_midline>R +    E+  +    Y  QI  G+ ++H  G+ H D+KP N++   +TG  +KI DFG A+KLE+ +       +  + APE+I    IG   Y T  D+W +G +   ++ G +   G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>87</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>1.8693e-07</Hsp_evalue>
      <Hsp_query-from>2374</Hsp_query-from>
      <Hsp_query-to>2631</Hsp_query-to>
      <Hsp_hit-from>174</Hsp_hit-from>
      <Hsp_hit-to>275</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>104</Hsp_align-len>
      <Hsp_qseq>MRQIVEGVQFMHRQGIVHLDLKPENIMC-----------LNQTGNR----IKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINYEPIGYAT---DMWSVGVIC</Hsp_qseq>
      <Hsp_hseq>LSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVENKNPYTAYVSTRWYRSPEILLRS--GYYSKPLDIWAFGCVA</Hsp_hseq>
      <Hsp_midline>+ QI+ G++ +H     H DLKPENI+            +NQ G +    IK+ DFGLAR +EN         T  + +PE++     GY +   D+W+ G + </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>88</Hit_num>
  <Hit_id>YFL033C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:69115:74427:-1 gene:YFL033C transcript:YFL033C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM15 description:Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase [Source:SGD;Acc:S000001861]</Hit_def>
  <Hit_accession>YFL033C</Hit_accession>
  <Hit_len>1770</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>2.32484e-07</Hsp_evalue>
      <Hsp_query-from>2347</Hsp_query-from>
      <Hsp_query-to>2508</Hsp_query-to>
      <Hsp_hit-from>890</Hsp_hit-from>
      <Hsp_hit-to>941</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>24</Hsp_identity>
      <Hsp_positive>36</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>54</Hsp_align-len>
      <Hsp_qseq>LTERECIKYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLAR</Hsp_qseq>
      <Hsp_hseq>LPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLIDN--AGHVKLTDFGLSR</Hsp_hseq>
      <Hsp_midline>L ++   +Y+ +IV GV  MH+ GI+H DLKPEN++  N     +K+ DFGL+R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>89</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>3.64925e-07</Hsp_evalue>
      <Hsp_query-from>2368</Hsp_query-from>
      <Hsp_query-to>2628</Hsp_query-to>
      <Hsp_hit-from>115</Hsp_hit-from>
      <Hsp_hit-to>201</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>89</Hsp_align-len>
      <Hsp_qseq>KYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLEN-VKNLKVMFGTPEFVAPEV-INYEPIGYATDMWSVGVI</Hsp_qseq>
      <Hsp_hseq>KFMMQLCKGIAYCHSHRILHRDLKPQNLL-INKDGN-LKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCI</Hsp_hseq>
      <Hsp_midline>K+M Q+ +G+ + H   I+H DLKP+N++ +N+ GN +K+ DFGLAR     ++       T  + APEV +  +      D WS+G I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>90</Hit_num>
  <Hit_id>YAR018C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:170396:171703:-1 gene:YAR018C transcript:YAR018C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN3 description:Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol [Source:SGD;Acc:S000000071]</Hit_def>
  <Hit_accession>YAR018C</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>6.67487e-07</Hsp_evalue>
      <Hsp_query-from>2479</Hsp_query-from>
      <Hsp_query-to>2898</Hsp_query-to>
      <Hsp_hit-from>227</Hsp_hit-from>
      <Hsp_hit-to>359</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>141</Hsp_align-len>
      <Hsp_qseq>IKIIDFGLARKLE-NVKNLKVMFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVEHPWLQMDTEHMAAKKLSKERMKRYL</Hsp_qseq>
      <Hsp_hseq>VKLGDFGLAKSLETSIQFATTYVGTPYYMSPEVLMDQPYSPLSDIWSLGCVIFEMCSLHPPFQAKNYLELQTKIKNGKCDTVPEYY---SRGLNAIIHSMIDVNLRTRPSTFELLQD--IQIRT---ARKSLQLERFERKL</Hsp_hseq>
      <Hsp_midline>+K+ DFGLA+ LE +++      GTP +++PEV+  +P    +D+WS+G + + + S   P    N  E    + +   D   E +   S      I  ++  N++ R +  + ++   +Q+ T   A K L  ER +R L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>91</Hit_num>
  <Hit_id>YNL020C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:595623:597539:-1 gene:YNL020C transcript:YNL020C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ARK1 description:Serine/threonine protein kinase; involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis; ARK1 has a paralog, PRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004965]</Hit_def>
  <Hit_accession>YNL020C</Hit_accession>
  <Hit_len>638</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>6.85801e-07</Hsp_evalue>
      <Hsp_query-from>2347</Hsp_query-from>
      <Hsp_query-to>2823</Hsp_query-to>
      <Hsp_hit-from>129</Hsp_hit-from>
      <Hsp_hit-to>294</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>174</Hsp_align-len>
      <Hsp_qseq>LTERECIKYMRQIVEGVQFMH--RQGIVHLDLKPENIMCLNQTGNRIKIIDFGL----------ARKLENVKNLKVMFGTPEFVAPEVINY---EPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVE</Hsp_qseq>
      <Hsp_hseq>LHEFEILQIMSQVTQGVAAMHALQPPLIHRDIKIENVLI--SANNEYKLCDFGSVCGIIRPPRNSQELSYVQQDILKNTTAQYRSPEMIDTFRGLPIDEKSDIWALGIFLYKLCYYTTPFEKGGD---LA-ILSGKFEF--PLYPNYSEQLKGLIRDILVQDPRHRPNVYQLLK</Hsp_hseq>
      <Hsp_midline>L E E ++ M Q+ +GV  MH  +  ++H D+K EN++      N  K+ DFG           +++L  V+   +   T ++ +PE+I+     PI   +D+W++G+  Y L    +P     D   LA + S  ++F    +   SE  K  I  +L ++ + R    Q ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>92</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>1.12812e-06</Hsp_evalue>
      <Hsp_query-from>2368</Hsp_query-from>
      <Hsp_query-to>2808</Hsp_query-to>
      <Hsp_hit-from>112</Hsp_hit-from>
      <Hsp_hit-to>258</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>164</Hsp_align-len>
      <Hsp_qseq>KYMRQIVEGVQFMHRQGIVHLDLKPENIMCLNQTGNRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVI-----------NYE----PI--GYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTC</Hsp_qseq>
      <Hsp_hseq>KIIKQLCSAISFAHSLGIAHRDIKPENIL-LTINGD-IKLADWGHA--IQSPKSNDFQIGTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFG----------DCLFRVSKSKKVQHLKNFDEFEKDPFAFI---YRKYVVPRLSC</Hsp_hseq>
      <Hsp_midline>K ++Q+   + F H  GI H D+KPENI+ L   G+ IK+ D+G A  +++ K+     GT  + APE             N++    P+   Y  D WS+G   + L+ G          + L  V+ +      + FDE  +D   FI    +K +  RL+C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>93</Hit_num>
  <Hit_id>YIL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:183937:186369:1 gene:YIL095W transcript:YIL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRK1 description:Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton and reduces endocytic ability of cell through the phosphorylation of the Pan1p-Sla1p-End3p protein complex; PRK1 has a paralog, ARK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001357]</Hit_def>
  <Hit_accession>YIL095W</Hit_accession>
  <Hit_len>810</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>2.21412e-06</Hsp_evalue>
      <Hsp_query-from>2347</Hsp_query-from>
      <Hsp_query-to>2823</Hsp_query-to>
      <Hsp_hit-from>128</Hsp_hit-from>
      <Hsp_hit-to>293</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>174</Hsp_align-len>
      <Hsp_qseq>LTERECIKYMRQIVEGVQFMH--RQGIVHLDLKPENIMCLNQTGNRIKIIDFGLA----------RKLENVKNLKVMFGTPEFVAPEVINYE---PIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTSATWDFDDEAFDEISEDSKDFISHLLQKNMKERLTCTQCVE</Hsp_qseq>
      <Hsp_hseq>LQESEILEIMSQTVQGITAMHALQPPLIHRDIKIENVL-ISHDG-LYKVCDFGSVSGVIRPPRNTQEFNYVQHDILTNTTAQYRSPEMIDLYRGLPIDEKSDIWALGVFLYKICYYTTPFEKSGE----AGILHARYQY--PSFPQYSDRLKNLIRLMLMEAPSQRPNICQVLE</Hsp_hseq>
      <Hsp_midline>L E E ++ M Q V+G+  MH  +  ++H D+K EN++ ++  G   K+ DFG            ++   V++  +   T ++ +PE+I+     PI   +D+W++GV  Y +    +P     +    A +  A + +   +F + S+  K+ I  +L +   +R    Q +E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>94</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>2.8648e-06</Hsp_evalue>
      <Hsp_query-from>2473</Hsp_query-from>
      <Hsp_query-to>2778</Hsp_query-to>
      <Hsp_hit-from>553</Hsp_hit-from>
      <Hsp_hit-to>650</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>104</Hsp_align-len>
      <Hsp_qseq>NRIKIIDFGLARKLENVKNLKVMFGTPEFVAPEVINYEPIGYATDMWSVGVICYILVSGLSPLMGDNDNETLANVTS--ATWDFDDEAFDEISEDSKDFISHLL</Hsp_qseq>
      <Hsp_hseq>NRQQIQTWRKSRRLMAYSTV----GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDI--HISYEAEDLIRRLL</Hsp_hseq>
      <Hsp_midline>NR +I  +  +R+L     +    GTP+++APE+  Y+  G   D WS+G I Y  + G  P   +   ET   + +   T  F D+    IS +++D I  LL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2780116679</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0051755-RA transcript Note:&quot;Similar to RBMS3 RNA-binding motif, single-stranded-interacting protein 3 (Pongo abelii)&quot; offset:77 AED:0.02 eAED:0.02 QI:77|1|1|1|0|0.3|10|2910|245</Iteration_query-def>
  <Iteration_query-len>3725</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2562112380</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0011061-RA transcript Note:&quot;Similar to TDRD15 Tudor domain-containing protein 15 (Homo sapiens)&quot; offset:34 AED:0.37 eAED:0.39 QI:34|0.37|0.23|0.70|0|0.05|17|234|1167</Iteration_query-def>
  <Iteration_query-len>3772</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2598071852</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0040250-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0|0|2|0|76</Iteration_query-def>
  <Iteration_query-len>231</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>49</Statistics_hsp-len>
      <Statistics_eff-space>72538676</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0026593-RA transcript Note:&quot;Similar to DGKB Diacylglycerol kinase beta (Homo sapiens)&quot; offset:0 AED:0.31 eAED:0.32 QI:0|0|0|0.52|0.13|0.17|23|91|802</Iteration_query-def>
  <Iteration_query-len>2500</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1666441245</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0029419-RA transcript Note:&quot;Similar to ETV1 ETS translocation variant 1 (Bos taurus)&quot; offset:78 AED:1.00 eAED:1.00 QI:78|0|0|0|0.33|0.5|4|0|81</Iteration_query-def>
  <Iteration_query-len>324</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>76</Statistics_hsp-len>
      <Statistics_eff-space>77198944</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0010968-RA transcript Note:&quot;Similar to Etv5 ETS translocation variant 5 (Mus musculus)&quot; offset:0 AED:0.54 eAED:0.54 QI:0|0.33|0.28|0.57|0.33|0.42|7|0|494</Iteration_query-def>
  <Iteration_query-len>1485</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>919760467</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0051757-RA transcript Note:&quot;Similar to Avl9 Late secretory pathway protein AVL9 homolog (Mus musculus)&quot; offset:297 AED:0.18 eAED:0.18 QI:297|1|1|1|0.2|0.31|16|2897|676</Iteration_query-def>
  <Iteration_query-len>5225</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YLR114C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:374944:377238:-1 gene:YLR114C transcript:YLR114C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AVL9 description:Conserved protein involved in exocytic transport from the Golgi; mutation is synthetically lethal with apl2 vps1 double mutation; member of a protein superfamily with orthologs in diverse organisms; relocalizes from bud neck to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000004104]</Hit_def>
  <Hit_accession>YLR114C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>117.472</Hsp_bit-score>
      <Hsp_score>293</Hsp_score>
      <Hsp_evalue>6.18799e-27</Hsp_evalue>
      <Hsp_query-from>319</Hsp_query-from>
      <Hsp_query-to>981</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>237</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>82</Hsp_identity>
      <Hsp_positive>136</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>244</Hsp_align-len>
      <Hsp_qseq>DESKGGPVLHVAVVGFHHKKGCQVEFSY--PPLLEKEGHDSHSLPEEWKYLPFLALPDGAHNFQEDTVFFLL------------PARD------GEKGTVYGVSCYKQIEAKTLKVREADVTRETVQKSVCVLSNTPLFGLLQAKLQLITHAYFEEKDFSQISILKELYDHVNSSLK-GSLLEGSQA--FLGLSARDLVLRXXXXXXXXXXXXXXXXXXXXXGSPVHKLVSPMIALLSLFPGMI</Hsp_qseq>
      <Hsp_hseq>DEHEEAVIFGICLVDFHHKRGPEIEYWYGLP-----EGTQSAEL---WPNLPFQALPDGSHSFEETFTYFTLLYDERRQRSPPNGATDLSDDSINDNTTLFAISCSRQIKSDELVTKDKDVTRSTVQKAIVVISRQPIFGQIKDKLSIVTNAFFLQHDFGDRKIIQSLYENLKSIYTPASLVRNAENRLYIGLCLRKILHDFKRNALVLLKAIMLEKKIIVYGNDVEALCNLQFGLISLIPDLM</Hsp_hseq>
      <Hsp_midline>DE +   +  + +V FHHK+G ++E+ Y  P     EG  S  L   W  LPF ALPDG+H+F+E   +F L             A D       +  T++ +SC +QI++  L  ++ DVTR TVQK++ V+S  P+FG ++ KL ++T+A+F + DF    I++ LY+++ S     SL+  ++   ++GL  R ++  FK   L+L K ++LEKK++  G+ V  L +    L+SL P ++</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>80.1073</Hsp_bit-score>
      <Hsp_score>196</Hsp_score>
      <Hsp_evalue>1.84332e-15</Hsp_evalue>
      <Hsp_query-from>1582</Hsp_query-from>
      <Hsp_query-to>2157</Hsp_query-to>
      <Hsp_hit-from>274</Hsp_hit-from>
      <Hsp_hit-to>490</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>217</Hsp_align-len>
      <Hsp_qseq>GMPLPIFTKGYLLLPYMALQQHHLLSDVSVRGFLAGATNVLFRQQK-HLSDVIVDVEECRLEIQDPELRRMLALGTADLRFADWLVKHVADN---RQDVFLDGTGWEGGDEWVRSQFSFYLLSLLATT-------LQPDNEKLLAD-------------FGMGFVTAWQDTHNYRVWNSNTHPGMDDV-QAGHAFHGQYSVADVKLRLAHSVSNSER</Hsp_qseq>
      <Hsp_hseq>GFPLPIFEKGGLFSPYTPLQQMNDIRSERTLFFMIGSSNTLLAEQKEELCHIFVNTDNSTVDILDKTLNPVLQLSSHDKKWIESISGIVSDTWNENDDETPKNSQFEGSEDFIRWQFEDYLTGLLSSVKLSDYLDLHKENDQALKTIPEDMLNSNPVHLFNLNWVQSWKETQNFLIFNSRTDDRLFDLFPPKHIYNGADTLSLLQQRFLATFHNLKR</Hsp_hseq>
      <Hsp_midline>G PLPIF KG L  PY  LQQ + +       F+ G++N L  +QK  L  + V+ +   ++I D  L  +L L + D ++ + +   V+D      D     + +EG ++++R QF  YL  LL++        L  +N++ L               F + +V +W++T N+ ++NS T   + D+    H ++G  +++ ++ R   +  N +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3659729346</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0010340-RA transcript Note:&quot;Similar to nckap1 Nck-associated protein 1 (Danio rerio)&quot; offset:0 AED:0.17 eAED:0.17 QI:0|0|0|0.72|0.64|0.72|29|1624|994</Iteration_query-def>
  <Iteration_query-len>4609</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3201704611</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0006148-RA transcript Note:&quot;Similar to Sfrp4 Secreted frizzled-related protein 4 (Rattus norvegicus)&quot; offset:0 AED:0.36 eAED:0.36 QI:0|0.4|0.16|1|0|0|6|0|337</Iteration_query-def>
  <Iteration_query-len>1014</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>575376616</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0051758-RA transcript Note:&quot;Similar to DUSP19 Dual specificity protein phosphatase 19 (Homo sapiens)&quot; offset:216 AED:0.02 eAED:0.02 QI:216|1|1|1|0|0|5|380|238</Iteration_query-def>
  <Iteration_query-len>1313</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YIR026C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:404873:405967:-1 gene:YIR026C transcript:YIR026C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YVH1 description:Dual specificity protein phosphatase; regulates growth, sporulation, and glycogen accumulation in a cAMP-dependent protein kinase cascade dependent manner; mutants are defective in 60S ribosome assembly; positively regulates pre-autophagosomal structure (PAS) formation upon nitrogen starvation or rapamycin treatment [Source:SGD;Acc:S000001465]</Hit_def>
  <Hit_accession>YIR026C</Hit_accession>
  <Hit_len>364</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>5.55753e-12</Hsp_evalue>
      <Hsp_query-from>478</Hsp_query-from>
      <Hsp_query-to>888</Hsp_query-to>
      <Hsp_hit-from>7</Hsp_hit-from>
      <Hsp_hit-to>164</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>SVDLQVGVVKPWLLLGSQDVAQDIRTL-QQHKVSHILNVAYGVDNAFPDSYIYKIVTMLDVP--DTKLTN---YFPECFDFIS-----------------RAHKQGGVVLVHCNAGVSRAASVIIGYLIQEDGLSFQDAFSLVKRARPAAHPNSGFMQQL</Hsp_qseq>
      <Hsp_hseq>SVDEEVTRILGGIYLGGIRPIIDHRPLGAEFNITHILSVIKF--QVIPEYLIRKGYTLKNIPIDDDDVTDVLQYFDETNRFIDQCLFPNEVEYSPRLVDFKKKPQRGAVFAHCQAGLSRSVTFIVAYLMYRYGLSLSMAMHAVKRKKPSVEPNENFMEQL</Hsp_hseq>
      <Hsp_midline>SVD +V  +   + LG      D R L  +  ++HIL+V        P+  I K  T+ ++P  D  +T+   YF E   FI                  +   Q G V  HC AG+SR+ + I+ YL+   GLS   A   VKR +P+  PN  FM+QL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YNL053W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:529942:531411:1 gene:YNL053W transcript:YNL053W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MSG5 description:Dual-specificity protein phosphatase; exists in 2 isoforms; required for maintenance of a low level of signaling through the cell integrity pathway, adaptive response to pheromone; regulates and is regulated by Slt2p; dephosphorylates Fus3p; MSG5 has a paralog, SDP1, that arose from the whole genome duplication [Source:SGD;Acc:S000004998]</Hit_def>
  <Hit_accession>YNL053W</Hit_accession>
  <Hit_len>489</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>1.12208e-11</Hsp_evalue>
      <Hsp_query-from>499</Hsp_query-from>
      <Hsp_query-to>930</Hsp_query-to>
      <Hsp_hit-from>237</Hsp_hit-from>
      <Hsp_hit-to>384</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>153</Hsp_align-len>
      <Hsp_qseq>VVKPWLLLGSQDVAQDIRTLQQHKVSHILNVAYGVDNA---FPDSYIYKI--VTMLDVPDTKLTNYFPECFDFISRAHKQGGVVLVHCNAGVSRAASVIIGYLIQEDGLSFQDAFSLVKRARPAAHPNSGFMQQLSEY----NPCQQGQRGES</Hsp_qseq>
      <Hsp_hseq>VLPPNLYLYSEPKLEDILSFDL-----VINVAKEIPNLEFLIPPEMAHKIKYYHIEWTHTSKIVKDLSRLTRIIHTAHSQGKKILVHCQCGVSRSASLIVAYIMRYYGLSLNDAYNKLKGVAKDISPNMGLIFQLMEWGTMLSKNSPGEEGET</Hsp_hseq>
      <Hsp_midline>V+ P L L S+   +DI +        ++NVA  + N     P    +KI    +     +K+          I  AH QG  +LVHC  GVSR+AS+I+ Y+++  GLS  DA++ +K       PN G + QL E+    +    G+ GE+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>93</Statistics_hsp-len>
      <Statistics_eff-space>791291848</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0027967-RA transcript Note:&quot;Protein of unknown function&quot; offset:21 AED:1.00 eAED:1.00 QI:21|0|0|0|0|0|3|1|82</Iteration_query-def>
  <Iteration_query-len>268</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>60</Statistics_hsp-len>
      <Statistics_eff-space>73023943</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0051759-RA transcript Note:&quot;Similar to EPDR1 Mammalian ependymin-related protein 1 (Homo sapiens)&quot; offset:0 AED:0.12 eAED:0.12 QI:0|0|0.33|1|1|1|3|660|220</Iteration_query-def>
  <Iteration_query-len>1323</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>93</Statistics_hsp-len>
      <Statistics_eff-space>800492916</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0051760-RA transcript Note:&quot;Similar to dnajc10 DnaJ homolog subfamily C member 10 (Xenopus laevis)&quot; offset:618 AED:0.15 eAED:0.15 QI:618|0.90|1|1|0.14|0.09|22|2064|707</Iteration_query-def>
  <Iteration_query-len>4806</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YIR004W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:363221:364519:1 gene:YIR004W transcript:YIR004W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DJP1 description:Cytosolic J-domain-containing protein; required for peroxisomal protein import and involved in peroxisome assembly; facilitates import of Mim1p and Mim2p into the mitochondrial outer membrane; homologous to E. coli DnaJ [Source:SGD;Acc:S000001443]</Hit_def>
  <Hit_accession>YIR004W</Hit_accession>
  <Hit_len>432</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.337</Hsp_bit-score>
      <Hsp_score>194</Hsp_score>
      <Hsp_evalue>1.42302e-15</Hsp_evalue>
      <Hsp_query-from>661</Hsp_query-from>
      <Hsp_query-to>945</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>93</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>95</Hsp_align-len>
      <Hsp_qseq>VIGDDDYYQRLDVARDASSRDIRKAFKKLALTLHPDKNQDDPDAHEKFLKINRAYEVLKDEELRKKYDKYGEKGLDDQQQGGRYESWNFYRYDFG</Hsp_qseq>
      <Hsp_hseq>MVVDTEYYDLLGVSTTASSIEIKKAYRKKSIQEHPDKNPNDPTATERFQAISEAYQVLGDDDLRAKYDKYGRK--EAIPQGGFEDAAEQFSVIFG</Hsp_hseq>
      <Hsp_midline>++ D +YY  L V+  ASS +I+KA++K ++  HPDKN +DP A E+F  I+ AY+VL D++LR KYDKYG K  +   QGG  ++   +   FG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YMR161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:577718:578392:1 gene:YMR161W transcript:YMR161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HLJ1 description:Co-chaperone for Hsp40p; anchored in the ER membrane; with its homolog Ydj1p promotes ER-associated protein degradation (ERAD) of integral membrane substrates; similar to E. coli DnaJ [Source:SGD;Acc:S000004771]</Hit_def>
  <Hit_accession>YMR161W</Hit_accession>
  <Hit_len>224</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>4.65055e-14</Hsp_evalue>
      <Hsp_query-from>676</Hsp_query-from>
      <Hsp_query-to>927</Hsp_query-to>
      <Hsp_hit-from>21</Hsp_hit-from>
      <Hsp_hit-to>102</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>DYYQRLDVARDASSRDIRKAFKKLALTLHPDKNQDDPDAHEKFLKINRAYEVLKDEELRKKYDKYGEKGLDDQQQGGRYESWNF</Hsp_qseq>
      <Hsp_hseq>EFYEILKVDRKATDSEIKKAYRKLAIKLHPDKNS-HPKAGEAFKVINRAFEVLSNEEKRSIYDRIG-RDPDDRQMPSRGAASGF</Hsp_hseq>
      <Hsp_midline>++Y+ L V R A+  +I+KA++KLA+ LHPDKN   P A E F  INRA+EVL +EE R  YD+ G +  DD+Q   R  +  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YOR288C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:852121:853077:-1 gene:YOR288C transcript:YOR288C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MPD1 description:Member of the protein disulfide isomerase (PDI) family; interacts with and inhibits the chaperone activity of Cne1p; MPD1 overexpression in a pdi1 null mutant suppresses defects in Pdi1p functions such as carboxypeptidase Y maturation [Source:SGD;Acc:S000005814]</Hit_def>
  <Hit_accession>YOR288C</Hit_accession>
  <Hit_len>318</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>1.20157e-13</Hsp_evalue>
      <Hsp_query-from>943</Hsp_query-from>
      <Hsp_query-to>1296</Hsp_query-to>
      <Hsp_hit-from>23</Hsp_hit-from>
      <Hsp_hit-to>160</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>138</Hsp_align-len>
      <Hsp_qseq>GIYDDDAEVLTLDRGEFDAAV-SSGELFFVNFYSPRCSHCHELAPMWREFAKEMDGVIRVAAVNC--GDNRMMCRSKGIGSYPSLYVYRAGM----QPVK-------------YSGDRSKDDLVRFVMKYVTSKVTEL</Hsp_qseq>
      <Hsp_hseq>NFYDSDPHISELTPKSFDKAIHNTNYTSLVEFYAPWCGHCKKLSSTFRKAAKRLDGVVQVAAVNCDLNKNKALCAKYDVNGFPTLMVFRPPKIDLSKPIDNAKKSFSAHANEVYSGARTLAPIVDFSLSRIRSYVKKF</Hsp_hseq>
      <Hsp_midline>  YD D  +  L    FD A+ ++     V FY+P C HC +L+  +R+ AK +DGV++VAAVNC    N+ +C    +  +P+L V+R       +P+              YSG R+   +V F +  + S V + </Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>1.25127e-11</Hsp_evalue>
      <Hsp_query-from>2467</Hsp_query-from>
      <Hsp_query-to>2712</Hsp_query-to>
      <Hsp_hit-from>29</Hsp_hit-from>
      <Hsp_hit-to>111</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>PQTAEDLTPQKFNSEVLEGMEHWLVDFYTPWCGHCQIFAPEFEIAARLLKGKLRTGKVNC--QNDPHVCQSAGIHGYPTVMFYQ</Hsp_qseq>
      <Hsp_hseq>PHISE-LTPKSFDKAIHNTNYTSLVEFYAPWCGHCKKLSSTFRKAAKRLDGVVQVAAVNCDLNKNKALCAKYDVNGFPTLMVFR</Hsp_hseq>
      <Hsp_midline>P  +E LTP+ F+  +       LV+FY PWCGHC+  +  F  AA+ L G ++   VNC    +  +C    ++G+PT+M ++</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>3.50833e-11</Hsp_evalue>
      <Hsp_query-from>2128</Hsp_query-from>
      <Hsp_query-to>2373</Hsp_query-to>
      <Hsp_hit-from>29</Hsp_hit-from>
      <Hsp_hit-to>110</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>PSVVTLTPETYVSLVKQRKRDEVWMVDFYAPWCGPCQALLPEWKRMARMLSGMVQVGSVDC--QKHHALCQSEMVHAYPEIRLF</Hsp_qseq>
      <Hsp_hseq>PHISELTPKSFDKAI--HNTNYTSLVEFYAPWCGHCKKLSSTFRKAAKRLDGVVQVAAVNCDLNKNKALCAKYDVNGFPTLMVF</Hsp_hseq>
      <Hsp_midline>P +  LTP+++   +     +   +V+FYAPWCG C+ L   +++ A+ L G+VQV +V+C   K+ ALC    V+ +P + +F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YER048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:246982:248157:-1 gene:YER048C transcript:YER048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CAJ1 description:Nuclear type II J heat shock protein of the E. coli dnaJ family; contains a leucine zipper-like motif, binds to non-native substrates for presentation to Ssa3p, may function during protein translocation, assembly and disassembly [Source:SGD;Acc:S000000850]</Hit_def>
  <Hit_accession>YER048C</Hit_accession>
  <Hit_len>391</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>6.34928e-13</Hsp_evalue>
      <Hsp_query-from>661</Hsp_query-from>
      <Hsp_query-to>945</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>93</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>95</Hsp_align-len>
      <Hsp_qseq>VIGDDDYYQRLDVARDASSRDIRKAFKKLALTLHPDKNQDDPDAHEKFLKINRAYEVLKDEELRKKYDKYGEKGLDDQQQGGRYESWNFYRYDFG</Hsp_qseq>
      <Hsp_hseq>MVKETEYYDILGIKPEATPTEIKKAYRRKAMETHPDKHPDDPDAQAKFQAVGEAYQVLSDPGLRSKYDQFGKE--DAVPQQGFEDASEYFTAIFG</Hsp_hseq>
      <Hsp_midline>++ + +YY  L +  +A+  +I+KA+++ A+  HPDK+ DDPDA  KF  +  AY+VL D  LR KYD++G++  D   Q G  ++  ++   FG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YMR214W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:695350:696483:1 gene:YMR214W transcript:YMR214W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCJ1 description:One of several homologs of bacterial chaperone DnaJ; located in the ER lumen where it cooperates with Kar2p to mediate maturation of proteins [Source:SGD;Acc:S000004827]</Hit_def>
  <Hit_accession>YMR214W</Hit_accession>
  <Hit_len>377</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>2.10966e-12</Hsp_evalue>
      <Hsp_query-from>676</Hsp_query-from>
      <Hsp_query-to>873</Hsp_query-to>
      <Hsp_hit-from>23</Hsp_hit-from>
      <Hsp_hit-to>88</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>28</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>66</Hsp_align-len>
      <Hsp_qseq>DYYQRLDVARDASSRDIRKAFKKLALTLHPDKNQDDPDAHEKFLKINRAYEVLKDEELRKKYDKYG</Hsp_qseq>
      <Hsp_hseq>DYYAILEIDKDATEKEIKSAYRQLSKKYHPDKNAGSEEAHQKFIEVGEAYDVLSDPEKKKIYDQFG</Hsp_hseq>
      <Hsp_midline>DYY  L++ +DA+ ++I+ A+++L+   HPDKN    +AH+KF+++  AY+VL D E +K YD++G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YNL077W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:481391:482977:1 gene:YNL077W transcript:YNL077W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:APJ1 description:Chaperone with a role in SUMO-mediated protein degradation; member of the DnaJ-like family; conserved across eukaryotes; overexpression interferes with propagation of the [Psi+] prion; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; forms nuclear foci upon DNA replication stress [Source:SGD;Acc:S000005021]</Hit_def>
  <Hit_accession>YNL077W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>1.16995e-10</Hsp_evalue>
      <Hsp_query-from>682</Hsp_query-from>
      <Hsp_query-to>873</Hsp_query-to>
      <Hsp_hit-from>8</Hsp_hit-from>
      <Hsp_hit-to>71</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>42</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>64</Hsp_align-len>
      <Hsp_qseq>YQRLDVARDASSRDIRKAFKKLALTLHPDKNQDDPDAHEKFLKINRAYEVLKDEELRKKYDKYG</Hsp_qseq>
      <Hsp_hseq>YDSLNVTAAASTSEIKKAYRNAALKYHPDKNNHTEESKRKFQEICQAYEILKDNRLRALYDQYG</Hsp_hseq>
      <Hsp_midline>Y  L+V   AS+ +I+KA++  AL  HPDKN    ++  KF +I +AYE+LKD  LR  YD+YG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YCL043C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:48653:50221:-1 gene:YCL043C transcript:YCL043C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PDI1 description:Protein disulfide isomerase; multifunctional oxidoreductase of the ER lumen, essential for disulfide bond formation in secretory and cell-surface proteins, processing of non-native disulfide bonds; Ero1p activator; complexes with exomannosidase, Mnl1p to facilitate the recognition of misfolded glycoproteins and the trimming of glycan Man8GlcNAc2 to Man7GlcNAc2 on substrates, thereby accelerating ERAD; PDI1 has a paralog, EUG1, that arose from the whole genome duplication [Source:SGD;Acc:S000000548]</Hit_def>
  <Hit_accession>YCL043C</Hit_accession>
  <Hit_len>522</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>2.32325e-10</Hsp_evalue>
      <Hsp_query-from>955</Hsp_query-from>
      <Hsp_query-to>1269</Hsp_query-to>
      <Hsp_hit-from>30</Hsp_hit-from>
      <Hsp_hit-to>137</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>108</Hsp_align-len>
      <Hsp_qseq>DDAEVLTLDRGEFDAAVSSGELFFVNFYSPRCSHCHELAPMWREFAKEM-DGVIRVAAVNCGDNRMMCRSKGIGSYPSLYVYRAG--MQPVKYSGDRSKDDLVRFVMK</Hsp_qseq>
      <Hsp_hseq>EDSAVVKLATDSFNEYIQSHDLVLAEFFAPWCGHCKNMAPEYVKAAETLVEKNITLAQIDCTENQDLCMEHNIPGFPSLKIFKNSDVNNSIDYEGPRTAEAIVQFMIK</Hsp_hseq>
      <Hsp_midline>+D+ V+ L    F+  + S +L    F++P C HC  +AP + + A+ + +  I +A ++C +N+ +C    I  +PSL +++       + Y G R+ + +V+F++K</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>8.43219e-08</Hsp_evalue>
      <Hsp_query-from>2485</Hsp_query-from>
      <Hsp_query-to>2712</Hsp_query-to>
      <Hsp_hit-from>37</Hsp_hit-from>
      <Hsp_hit-to>112</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>23</Hsp_identity>
      <Hsp_positive>43</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>77</Hsp_align-len>
      <Hsp_qseq>LTPQKFNSEVLEGMEHWLVDFYTPWCGHCQIFAPEFEIAAR-LLKGKLRTGKVNCQNDPHVCQSAGIHGYPTVMFYQ</Hsp_qseq>
      <Hsp_hseq>LATDSFN-EYIQSHDLVLAEFFAPWCGHCKNMAPEYVKAAETLVEKNITLAQIDCTENQDLCMEHNIPGFPSLKIFK</Hsp_hseq>
      <Hsp_midline>L    FN E ++  +  L +F+ PWCGHC+  APE+  AA  L++  +   +++C  +  +C    I G+P++  ++</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>1.85611e-07</Hsp_evalue>
      <Hsp_query-from>2113</Hsp_query-from>
      <Hsp_query-to>2373</Hsp_query-to>
      <Hsp_hit-from>24</Hsp_hit-from>
      <Hsp_hit-to>111</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>22</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>91</Hsp_align-len>
      <Hsp_qseq>QDLMSP---SVVTLTPETYVSLVKQRKRDEVWMVDFYAPWCGPCQALLPEWKRMARML-SGMVQVGSVDCQKHHALCQSEMVHAYPEIRLF</Hsp_qseq>
      <Hsp_hseq>QEAVAPEDSAVVKLATDSFNEYIQSH---DLVLAEFFAPWCGHCKNMAPEYVKAAETLVEKNITLAQIDCTENQDLCMEHNIPGFPSLKIF</Hsp_hseq>
      <Hsp_midline>Q+ ++P   +VV L  +++   ++     ++ + +F+APWCG C+ + PE+ + A  L    + +  +DC ++  LC    +  +P +++F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YIL005W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:345692:347797:1 gene:YIL005W transcript:YIL005W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:EPS1 description:ER protein with chaperone and co-chaperone activity; involved in retention of resident ER proteins; has a role in recognizing proteins targeted for ER-associated degradation (ERAD), member of the protein disulfide isomerase family [Source:SGD;Acc:S000001267]</Hit_def>
  <Hit_accession>YIL005W</Hit_accession>
  <Hit_len>701</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>3.13123e-10</Hsp_evalue>
      <Hsp_query-from>2200</Hsp_query-from>
      <Hsp_query-to>2679</Hsp_query-to>
      <Hsp_hit-from>52</Hsp_hit-from>
      <Hsp_hit-to>240</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>195</Hsp_align-len>
      <Hsp_qseq>MVDFYAPWCGPCQALLPEW-------KRMARMLSGMVQVGSVDCQKHHALCQSEMVHAYPEIRLFPMNPASSDKYFKYNGWHRDANSLKGWAF--GYLPQTAE-DLTPQKFNSEVLEGMEHW-----------LVDFYTPW-------------CGHCQIFAPEFEIAARLLK-GKLRTGKVNCQNDPHVCQSAG</Hsp_qseq>
      <Hsp_hseq>IIDFYSPYCPHCKHLAPVWMETWEEFKEESKTLN--ITFSQVNCIESADLCGDENIEYFPEIRLY--NPSGYIKSFTETP--RTKESLIAFARRESMDPNNLDTDLDSAKSESQYLEGFDFLELIAGKATRPHLVSFWPTKDMKNSDDSLEFKNCDKCHEFQRTWKIISRQLAVDDINTGHVNCESNPTICEELG</Hsp_hseq>
      <Hsp_midline>++DFY+P+C  C+ L P W       K  ++ L+  +    V+C +   LC  E +  +PEIRL+  NP+   K F      R   SL  +A      P   + DL   K  S+ LEG +             LV F+                C  C  F   ++I +R L    + TG VNC+++P +C+  G</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>4.23302e-07</Hsp_evalue>
      <Hsp_query-from>976</Hsp_query-from>
      <Hsp_query-to>1269</Hsp_query-to>
      <Hsp_hit-from>37</Hsp_hit-from>
      <Hsp_hit-to>139</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>104</Hsp_align-len>
      <Hsp_qseq>LDRGEFDAAVSSGELFFVNFYSPRCSHCHELAPM----WREFAKEMDGV-IRVAAVNCGDNRMMCRSKGIGSYPSLYVYR-AGMQPVKYSGDRSKDDLVRFVMK</Hsp_qseq>
      <Hsp_hseq>LNPTNFKEELSKG-LHIIDFYSPYCPHCKHLAPVWMETWEEFKEESKTLNITFSQVNCIESADLCGDENIEYFPEIRLYNPSGYIKSFTETPRTKESLIAFARR</Hsp_hseq>
      <Hsp_midline>L+   F   +S G L  ++FYSP C HC  LAP+    W EF +E   + I  + VNC ++  +C  + I  +P + +Y  +G         R+K+ L+ F  +</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>3.39896e-06</Hsp_evalue>
      <Hsp_query-from>2479</Hsp_query-from>
      <Hsp_query-to>2730</Hsp_query-to>
      <Hsp_hit-from>35</Hsp_hit-from>
      <Hsp_hit-to>121</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>27</Hsp_identity>
      <Hsp_positive>43</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>91</Hsp_align-len>
      <Hsp_qseq>EDLTPQKFNSEVLEGMEHWLVDFYTPWCGHCQIFAP-------EFEIAARLLKGKLRTGKVNCQNDPHVCQSAGIHGYPTVMFYQYQGRSK</Hsp_qseq>
      <Hsp_hseq>EPLNPTNFKEELSKGLH--IIDFYSPYCPHCKHLAPVWMETWEEFKEESKTL--NITFSQVNCIESADLCGDENIEYFPEIRLYNPSGYIK</Hsp_hseq>
      <Hsp_midline>E L P  F  E+ +G+   ++DFY+P+C HC+  AP       EF+  ++ L   +   +VNC     +C    I  +P +  Y   G  K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YNL064C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:505868:507097:-1 gene:YNL064C transcript:YNL064C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YDJ1 description:Type I HSP40 co-chaperone; involved in regulation of HSP90 and HSP70 functions; acts as an adaptor that helps Rsp5p recognize cytosolic misfolded proteins for ubiquitination after heat shock; critical for determining cell size at Start as a function of growth rate; involved in protein translocation across membranes; member of the DnaJ family; chimeric protein in which human p58IPK J domain replaces yeast Ydj1p J domain can complement yeast ydj1 mutant [Source:SGD;Acc:S000005008]</Hit_def>
  <Hit_accession>YNL064C</Hit_accession>
  <Hit_len>409</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>5.60713e-10</Hsp_evalue>
      <Hsp_query-from>661</Hsp_query-from>
      <Hsp_query-to>885</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>74</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>48</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>75</Hsp_align-len>
      <Hsp_qseq>VIGDDDYYQRLDVARDASSRDIRKAFKKLALTLHPDKNQDDPDAHEKFLKINRAYEVLKDEELRKKYDKYGEKGL</Hsp_qseq>
      <Hsp_hseq>MVKETKFYDILGVPVTATDVEIKKAYRKCALKYHPDKNPSE-EAAEKFKEASAAYEILSDPEKRDIYDQFGEDGL</Hsp_hseq>
      <Hsp_midline>++ +  +Y  L V   A+  +I+KA++K AL  HPDKN  + +A EKF + + AYE+L D E R  YD++GE GL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YLR090W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:320701:322080:1 gene:YLR090W transcript:YLR090W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:XDJ1 description:Chaperone with a role in facilitating mitochondrial protein import; ascomycete-specific member of the DnaJ-like family, closely related to Ydj1p; predicted to be C-terminally prenylated; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [Source:SGD;Acc:S000004080]</Hit_def>
  <Hit_accession>YLR090W</Hit_accession>
  <Hit_len>459</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>2.54972e-09</Hsp_evalue>
      <Hsp_query-from>673</Hsp_query-from>
      <Hsp_query-to>876</Hsp_query-to>
      <Hsp_hit-from>8</Hsp_hit-from>
      <Hsp_hit-to>78</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>71</Hsp_align-len>
      <Hsp_qseq>DDYYQRLDVARDASSRDIRKAFKKLALTLHPDK--NQDDPDAHE-KFLKINRAYEVLKDEELRKKYDKYGE</Hsp_qseq>
      <Hsp_hseq>DRLYDVLGVTRDATVQEIKTAYRKLALKHHPDKYVDQDSKEVNEIKFKEITAAYEILSDPEKKSHYDLYGD</Hsp_hseq>
      <Hsp_midline>D  Y  L V RDA+ ++I+ A++KLAL  HPDK  +QD  + +E KF +I  AYE+L D E +  YD YG+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YNL227C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:220659:222431:-1 gene:YNL227C transcript:YNL227C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:JJJ1 description:Co-chaperone that stimulates the ATPase activity of Ssa1p; required for a late step of ribosome biogenesis; associated with the cytosolic large ribosomal subunit; contains a J-domain; mutation causes defects in fluid-phase endocytosis [Source:SGD;Acc:S000005171]</Hit_def>
  <Hit_accession>YNL227C</Hit_accession>
  <Hit_len>590</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>1.54279e-08</Hsp_evalue>
      <Hsp_query-from>679</Hsp_query-from>
      <Hsp_query-to>891</Hsp_query-to>
      <Hsp_hit-from>5</Hsp_hit-from>
      <Hsp_hit-to>76</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>72</Hsp_align-len>
      <Hsp_qseq>YYQRLDVARDASSRDIRKAFKKLALTLHPDKNQDD-PDAHEKFLKINRAYEVLKDEELRKKYDKYGEKGLDD</Hsp_qseq>
      <Hsp_hseq>YYELLGVETHASDLELKKAYRKKALQYHPDKNPDNVEEATQKFAVIRAAYEVLSDPQERAWYDSHKEQILND</Hsp_hseq>
      <Hsp_midline>YY+ L V   AS  +++KA++K AL  HPDKN D+  +A +KF  I  AYEVL D + R  YD + E+ L+D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YDR518W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1478608:1480161:1 gene:YDR518W transcript:YDR518W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:EUG1 description:Protein disulfide isomerase of the endoplasmic reticulum lumen; EUG1 has a paralog, PDI1, that arose from the whole genome duplication; function overlaps with that of Pdi1p; may interact with nascent polypeptides in the ER [Source:SGD;Acc:S000002926]</Hit_def>
  <Hit_accession>YDR518W</Hit_accession>
  <Hit_len>517</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>2.35062e-08</Hsp_evalue>
      <Hsp_query-from>2485</Hsp_query-from>
      <Hsp_query-to>2733</Hsp_query-to>
      <Hsp_hit-from>38</Hsp_hit-from>
      <Hsp_hit-to>119</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>84</Hsp_align-len>
      <Hsp_qseq>LTPQKFNSEVLEGMEHWLVDFYTPWCGHCQIFAPEFEIAARLLKG-KLRTGKVNCQNDPHVCQSAGIHGYPTVMFYQYQGRSKD</Hsp_qseq>
      <Hsp_hseq>LTEKKFKS-FIESHPLVLVEFFAPWCLHSQILRPHLEEAASILKEHNVPVVQIDCEANSMVCLQQTINTYPTLKIFK-NGRIFD</Hsp_hseq>
      <Hsp_midline>LT +KF S  +E     LV+F+ PWC H QI  P  E AA +LK   +   +++C+ +  VC    I+ YPT+  ++  GR  D</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>5.2682e-08</Hsp_evalue>
      <Hsp_query-from>961</Hsp_query-from>
      <Hsp_query-to>1296</Hsp_query-to>
      <Hsp_hit-from>33</Hsp_hit-from>
      <Hsp_hit-to>147</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>115</Hsp_align-len>
      <Hsp_qseq>AEVLTLDRGEFDAAVSSGELFFVNFYSPRCSHCHELAPMWREFAKEM-DGVIRVAAVNCGDNRMMCRSKGIGSYPSLYVYRAG--MQPVKYSGDRSKDDLVRFVMKYVTSKVTEL</Hsp_qseq>
      <Hsp_hseq>SDLLVLTEKKFKSFIESHPLVLVEFFAPWCLHSQILRPHLEEAASILKEHNVPVVQIDCEANSMVCLQQTINTYPTLKIFKNGRIFDGQVYRGVKITDEITQYMIQLYEASVIYL</Hsp_hseq>
      <Hsp_midline>+++L L   +F + + S  L  V F++P C H   L P   E A  + +  + V  ++C  N M+C  + I +YP+L +++ G       Y G +  D++ +++++   + V  L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YOR254C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:805032:807023:-1 gene:YOR254C transcript:YOR254C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SEC63 description:Essential subunit of Sec63 complex; with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER; other members are Sec62p, Sec66p, and Sec72p [Source:SGD;Acc:S000005780]</Hit_def>
  <Hit_accession>YOR254C</Hit_accession>
  <Hit_len>663</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>4.95534e-08</Hsp_evalue>
      <Hsp_query-from>676</Hsp_query-from>
      <Hsp_query-to>873</Hsp_query-to>
      <Hsp_hit-from>125</Hsp_hit-from>
      <Hsp_hit-to>196</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>44</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>72</Hsp_align-len>
      <Hsp_qseq>DYYQRLDVARDASSRDIRKAFKKLALTLHPDKNQD--DPD----AHEKFLKINRAYEVLKDEELRKKYDKYG</Hsp_qseq>
      <Hsp_hseq>DPYEILGISTSASDRDIKSAYRKLSVKFHPDKLAKGLTPDEKSVMEETYVQITKAYESLTDELVRQNYLKYG</Hsp_hseq>
      <Hsp_midline>D Y+ L ++  AS RDI+ A++KL++  HPDK      PD      E +++I +AYE L DE +R+ Y KYG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YJL073W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:303181:305118:1 gene:YJL073W transcript:YJL073W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:JEM1 description:DnaJ-like chaperone required for nuclear membrane fusion during mating; localizes to the ER membrane; exhibits genetic interactions with KAR2 [Source:SGD;Acc:S000003609]</Hit_def>
  <Hit_accession>YJL073W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>6.09791e-08</Hsp_evalue>
      <Hsp_query-from>676</Hsp_query-from>
      <Hsp_query-to>864</Hsp_query-to>
      <Hsp_hit-from>538</Hsp_hit-from>
      <Hsp_hit-to>605</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>40</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>68</Hsp_align-len>
      <Hsp_qseq>DYYQRLDVARDASSRDIRKAFKKLALTLHPDK-----NQDDPDAHEKFLKINRAYEVLKDEELRKKYD</Hsp_qseq>
      <Hsp_hseq>DYYKILGVSPSASSKEIRKAYLNLTKKYHPDKIKANHNDKQESIHETMSQINEAYETLSDDDKRKEYD</Hsp_hseq>
      <Hsp_midline>DYY+ L V+  ASS++IRKA+  L    HPDK     N      HE   +IN AYE L D++ RK+YD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YNL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:618507:619565:-1 gene:YNL007C transcript:YNL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SIS1 description:Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p; shuttles between cytosol and nucleus; mediates delivery of misfolded proteins into the nucleus for degradation; involved in proteasomal degradation of misfolded cytosolic proteins; protein abundance increases in response to DNA replication stress; polyQ aggregates sequester Sis1p and interfere with clearance of misfolded proteins; similar to bacterial DnaJ proteins and mammalian DnaJB1 [Source:SGD;Acc:S000004952]</Hit_def>
  <Hit_accession>YNL007C</Hit_accession>
  <Hit_len>352</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>1.75643e-07</Hsp_evalue>
      <Hsp_query-from>661</Hsp_query-from>
      <Hsp_query-to>873</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>68</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>26</Hsp_identity>
      <Hsp_positive>44</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>71</Hsp_align-len>
      <Hsp_qseq>VIGDDDYYQRLDVARDASSRDIRKAFKKLALTLHPDKNQDDPDAHEKFLKINRAYEVLKDEELRKKYDKYG</Hsp_qseq>
      <Hsp_hseq>MVKETKLYDLLGVSPSANEQELKKGYRKAALKYHPDKPTGD---TEKFKEISEAFEILNDPQKREIYDQYG</Hsp_hseq>
      <Hsp_midline>++ +   Y  L V+  A+ ++++K ++K AL  HPDK   D    EKF +I+ A+E+L D + R+ YD+YG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3349166233</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0051756-RA transcript Note:&quot;Similar to IFIH1 Interferon-induced helicase C domain-containing protein 1 (Homo sapiens)&quot; offset:65 AED:0.38 eAED:0.50 QI:65|0|0|1|0|0|2|0|94</Iteration_query-def>
  <Iteration_query-len>350</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>77</Statistics_hsp-len>
      <Statistics_eff-space>93828813</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0006228-RA transcript Note:&quot;Similar to XYLB Xylulose kinase (Homo sapiens)&quot; offset:217 AED:1.00 eAED:1.00 QI:217|0|0|0|0.42|0.45|20|1009|531</Iteration_query-def>
  <Iteration_query-len>2822</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YGR194C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:886073:887875:-1 gene:YGR194C transcript:YGR194C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:XKS1 description:Xylulokinase; converts D-xylulose and ATP to xylulose 5-phosphate and ADP; rate limiting step in fermentation of xylulose; required for xylose fermentation by recombinant S. cerevisiae strains [Source:SGD;Acc:S000003426]</Hit_def>
  <Hit_accession>YGR194C</Hit_accession>
  <Hit_len>600</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>276.944</Hsp_bit-score>
      <Hsp_score>707</Hsp_score>
      <Hsp_evalue>1.27129e-82</Hsp_evalue>
      <Hsp_query-from>233</Hsp_query-from>
      <Hsp_query-to>1669</Hsp_query-to>
      <Hsp_hit-from>21</Hsp_hit-from>
      <Hsp_hit-to>552</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>180</Hsp_identity>
      <Hsp_positive>271</Hsp_positive>
      <Hsp_gaps>57</Hsp_gaps>
      <Hsp_align-len>534</Hsp_align-len>
      <Hsp_qseq>GFVLGLDLSTQQVKAMXXXXXXXXXXXXXXXFDKDLPKFSTQGGVHIHEDKLTVTSPVLMWVEAIDLALERLVQSGVDLSQVAVLSGSGQQHGSVYWRQGAR---KTLHNAAASSPLHLTLQGCFSLDEVPVWMDSSTATECRQLEQALGGAQSLADITGSRAYERFTGNQIAKVYRTWPRAYEDTERIXXXXXXXXXXXXGNYATIDYSDGSGMNLLDIRKKCWTQRCL---DACAPD--LAEKLGELVPSHTVLGPVSSYLVQRYGFSPNCQVVAFSGDNPGSLAGMRLQAGDIAVSLGTSDTVFLWLKEPRPALEGHVFCNPICQEAYMALICFKNASLTRERVRDRC---------AAGSWEEFSRALRATPPGNGGNIGFYFDTMEITPPAVGIHR---FNTD----DEKVEAFADDV-EVRALVEGQFLAKRVHAEGL----------------------------GYRTEPETRILATGGASSNKDILQVLADVFNVPV--YTLDTANSACLGAAYRAKHGLLAASG</Hsp_qseq>
      <Hsp_hseq>SYYLGFDLSTQQLKCLAINQDLKIVHSETVEFEKDLPHYHTKKGVYIHGD--TIECPVAMWLEALDLVLSKYREAKFPLNKVMAVSGSCQQHGSVYWSSQAESLLEQLNKKPEKDLLHYVSSVAFARQTAPNWQDHSTAKQCQEFEECIGGPEKMAQLTGSRAHFRFTGPQILKIAQLEPEAYEKTKTISLVSNFLTSILVGHLVELEEADACGMNLYDIRERKFSDELLHLIDSSSKDKTIRQKLMRAPMKNLIAGTICKYFIEKYGFNTNCKVSPMTGDNLATICSLPLRKNDVLVSLGTSTTVLLVTDKYHPSPNYHLFIHPTLPNHYMGMICYCNGSLARERIRDELNKERENNYEKTNDWTLFNQAVLDDSESSENELGVYFPLGEIVPSVKAINKRVIFNPKTGMIEREVAKFKDKRHDAKNIVESQALSCRVRISPLLSDSNASSQQRLNEDTIVKFDYDESPLRDYLNKRPERTFFVGGASKNDAIVKKFAQVIGATKGNFRLETPNSCALGGCYKAMWSLLYDSN</Hsp_hseq>
      <Hsp_midline> + LG DLSTQQ+K + ++ +L ++    V F+KDLP + T+ GV+IH D  T+  PV MW+EA+DL L +  ++   L++V  +SGS QQHGSVYW   A    + L+       LH      F+    P W D STA +C++ E+ +GG + +A +TGSRA+ RFTG QI K+ +  P AYE T+ ISLVS+F  S+ +G+   ++ +D  GMNL DIR++ ++   L   D+ + D  + +KL      + + G +  Y +++YGF+ NC+V   +GDN  ++  + L+  D+ VSLGTS TV L   +  P+   H+F +P     YM +IC+ N SL RER+RD               W  F++A+      +   +G YF   EI P    I++   FN      + +V  F D   + + +VE Q L+ RV    L                             Y  +   R    GGAS N  I++  A V       + L+T NS  LG  Y+A   LL  S </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>1901220947</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0051770-RA transcript Note:&quot;Similar to ACVR2B Activin receptor type-2B (Gallus gallus)&quot; offset:330 AED:0.05 eAED:0.05 QI:330|1|1|1|0.66|0.7|10|3133|438</Iteration_query-def>
  <Iteration_query-len>4780</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>6.75407e-13</Hsp_evalue>
      <Hsp_query-from>730</Hsp_query-from>
      <Hsp_query-to>1221</Hsp_query-to>
      <Hsp_hit-from>609</Hsp_hit-from>
      <Hsp_hit-to>762</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>NEVAMFTAAGMKHENLLQFLAAERRGTGLDFEFWIITLFQHKGSVGDYLKGNV--------VTWSELCHIAETMARGLSFLHEEGPDLKPAIAHRDFKSKNVLLKSDLTACVADLGLAVKFEPGKPPGDMHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAVGLVMWELV</Hsp_qseq>
      <Hsp_hseq>NEILVMKDS--RHKNIVNFLEAYLRT---DDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKH------IIHRDIKSDNVLLDTRARVKITDFGFCARLTDKR--SKRATMVGTPYWMAPEVVK-----QREYDEKIDVWSLGIMTIEML</Hsp_hseq>
      <Hsp_midline>NE+ +   +  +H+N++ FL A  R    D + W++  F   GS+ D ++ +         +T  ++ +I     +GL FLH++       I HRD KS NVLL +     + D G   +    +        VGT  +MAPEV++     QR+   +ID++++G++  E++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>4.95051e-11</Hsp_evalue>
      <Hsp_query-from>637</Hsp_query-from>
      <Hsp_query-to>1221</Hsp_query-to>
      <Hsp_hit-from>628</Hsp_hit-from>
      <Hsp_hit-to>808</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>198</Hsp_align-len>
      <Hsp_qseq>RGRFGCVYRAQLPGQEVAVKVFPPEHKASWQNEVAM---FTAAGMKHENLLQFLAAERRGTGLDFEFWIITLFQHKGSVGDYLKGNVVTWSELCHIAETMARGLSFLHEEGPDLKPAIAHRDFKSKNVLLKSDLTACVADLGLAVKFEPGKPPGDMHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAVGLVMWELV</Hsp_qseq>
      <Hsp_hseq>QGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKELIINEILVMKGSKHPNIVNFIDSYV----LKGDLWVIMEYMEGGSLTDVVTHCILTEGQIGAVCRETLSGLEFLHSKG------VLHRDIKSDNILLSMEGDIKLTDFGFCAQINELN--LKRTTMVGTPYWMAPEVVS-----RKEYGPKVDIWSLGIMIIEMI</Hsp_hseq>
      <Hsp_midline>+G  G VY A   G  V+V +     +   + E+ +       G KH N++ F+ +      L  + W+I  +   GS+ D +   ++T  ++  +      GL FLH +G      + HRD KS N+LL  +    + D G   +             VGT  +MAPEV+      +++   ++D++++G+++ E++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>5.37697e-10</Hsp_evalue>
      <Hsp_query-from>643</Hsp_query-from>
      <Hsp_query-to>1221</Hsp_query-to>
      <Hsp_hit-from>389</Hsp_hit-from>
      <Hsp_hit-to>576</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>206</Hsp_align-len>
      <Hsp_qseq>RFGCVYRAQLPGQEVAVKVFPPEHKASWQ---NEVAMFTAAGMKHENLLQFLAAERRGTGLDFEFWIITLFQHKGSVGDYL----KGNV------VTWSELCHIAETMARGLSFLHEEGPDLKPAIAHRDFKSKNVLLKSDLTACVADLGLAVKFEPGKPPGDMHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAVGLVMWELV</Hsp_qseq>
      <Hsp_hseq>RFLKSHCHRVVGERVAIKQIRLSEQPKKQLIMNELLVMNDS--RQENIVNFLEAYIID---DEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNK------KIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKR--SKRATMVGTPYWMAPEIVN-----QKGYDEKVDVWSLGIMLIEMI</Hsp_hseq>
      <Hsp_midline>RF   +  ++ G+ VA+K      +   Q   NE+ +   +  + EN++ FL A       D E W+I  +   G + D L    + N       +  +++ +I +   +GL FLH +       I HRD KS N+LL S     + D G  V+    +        VGT  +MAPE++      Q+    ++D++++G+++ E++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>6.2362e-10</Hsp_evalue>
      <Hsp_query-from>637</Hsp_query-from>
      <Hsp_query-to>1218</Hsp_query-to>
      <Hsp_hit-from>1183</Hsp_hit-from>
      <Hsp_hit-to>1373</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>212</Hsp_align-len>
      <Hsp_qseq>RGRFGCVYR--AQLPGQEVAVK-VFPPEHKASWQNEVAMFTAAGMK----------HENLLQFLAAERRGTGLDFEFWIITLFQHK---GSVGDYLKGNVVTWSE--LCHIAETMARGLSFLHEEGPDLKPAIAHRDFKSKNVLLKSDLTACVADLGLAVKFEPGKPPGDMHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAVGLVMWEL</Hsp_qseq>
      <Hsp_hseq>KGSFGAVYLCLNVTTGEMMAVKQVEVPKY--SSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNN-------IYSLFLEYVAGGSVGSLIRM-YGRFDEPLIKHLTTQVLKGLAYLHSKG------ILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMR-GTVFWMAPEMVDTKQGYS----AKVDIWSLGCIVLEM</Hsp_hseq>
      <Hsp_midline>+G FG VY       G+ +AVK V  P++  S QNE  + T   ++          H N++Q+L  E +         I +LF      GSVG  ++     + E  + H+   + +GL++LH +G      I HRD K+ N+LL  D    ++D G++ K +      DM  + GT  +MAPE+++    +      ++D++++G ++ E+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>2.40537e-09</Hsp_evalue>
      <Hsp_query-from>637</Hsp_query-from>
      <Hsp_query-to>1458</Hsp_query-to>
      <Hsp_hit-from>31</Hsp_hit-from>
      <Hsp_hit-to>272</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>121</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>279</Hsp_align-len>
      <Hsp_qseq>RGRFGCVYRAQ--LPGQEVAVKVFPPEHKASWQNEV---AMFTAAGMKHENLLQFLAAERRGTGLDFEFWIITLFQHKGSVGDYLKGNVVTWSELCHIAETMARGLSFLHEEGPDLKPAIAHRDFKSKNVLLKSDLTACVADLGLAVKFEPGKPPGDMHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAVGLVMWELVSRCTVADGPVGDYRMPFEDEAGQHPSLEDMQEVVVNKKQRPALRDCWRKHPGLSQLCETVEECWDHDAEARLSAGCVVE</Hsp_qseq>
      <Hsp_hseq>RGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSL----WIIMEHCAGGSLRSLLRPGKIDEKYIGVIMRELLVALKCIHKDN------VIHRDIKAANVLITNEGNVKLCDFGVAAQV--NQTSLRRQTMAGTPYWMAPEVIMEGVYYD----TKVDIWSLGITTYEIAT----GNPPYCDVE-----------ALRAMQLII--KSKPPRLED--RSYS--TSLKEFIALCLDEDPKERLSADDLLK</Hsp_hseq>
      <Hsp_midline>RG+FG VY+      G+  A+KV   +  +    +V     F A+  +  N+ ++  +  + T L    WII      GS+   L+   +    +  I   +   L  +H++       + HRD K+ NVL+ ++    + D G+A +    +         GT  +MAPEV+   + +      ++D++++G+  +E+ +     + P  D             +L  MQ ++  K + P L D  R +   + L E +  C D D + RLSA  +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>5.07542e-09</Hsp_evalue>
      <Hsp_query-from>637</Hsp_query-from>
      <Hsp_query-to>1227</Hsp_query-to>
      <Hsp_hit-from>33</Hsp_hit-from>
      <Hsp_hit-to>214</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>203</Hsp_align-len>
      <Hsp_qseq>RGRFGCVYRA--QLPGQEVAVKVFPPEHKASWQNEVAMFTA-AGMKHENLLQFLAAERRGTGLDFEFWIITLFQHKGSVGDYLKGNVVTWSE---LCHIAETMARGLSFLHEEGPDLKPAIAHRDFKSKNVLLKSDLTACVADLGLAVKFEPGKPPGDMHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAVGLVMWELVSR</Hsp_qseq>
      <Hsp_hseq>RGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKS----YELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLL-GLKYLHGEG------VIHRDIKAANILLSADNTVKLADFGVSTIVNSSAL-----TLAGTLNWMAPEILGN-----RGASTLSDIWSLGATVVEMLTK</Hsp_hseq>
      <Hsp_midline>RG +G VY+A  +   Q VA+K    E+     + +A  +    + H N++++    R+     +E +I+  +   GS+   +  +    SE     ++ +T+  GL +LH EG      + HRD K+ N+LL +D T  +AD G++                GT  +MAPE+L       R A    D++++G  + E++++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>7.05066e-09</Hsp_evalue>
      <Hsp_query-from>637</Hsp_query-from>
      <Hsp_query-to>1221</Hsp_query-to>
      <Hsp_hit-from>26</Hsp_hit-from>
      <Hsp_hit-to>211</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>202</Hsp_align-len>
      <Hsp_qseq>RGRFGCVYRA--QLPGQEVAVKVFPPEHKASWQNEVA--MFTAAGMKHENLLQFLAAERRGTGLDFEFWIITLFQHKGSVGDYLKGNVVT---WSELCHIAETMARGLSFLHEEGPDLKPAIAHRDFKSKNVLLKSDLTACVADLGLAVKFEPGKPPGDMHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAVGLVMWELV</Hsp_qseq>
      <Hsp_hseq>RGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIATMLE----DVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRK------IHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRDTF---VGTPYWMAPEVVCCEVDGYNE---KADIWSLGITTYELL</Hsp_hseq>
      <Hsp_midline>RG FG VY+A  ++  + VA+KV   EH       +A  +F  A +K   +  ++A        D   WI+  +   GS  D LK + V      ++  I   +  GL +LHE+         HRD K+ N+LL  +    + D G++               VGT  +MAPEV+   ++   +   + D++++G+  +EL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>1.41609e-08</Hsp_evalue>
      <Hsp_query-from>637</Hsp_query-from>
      <Hsp_query-to>1224</Hsp_query-to>
      <Hsp_hit-from>23</Hsp_hit-from>
      <Hsp_hit-to>217</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>210</Hsp_align-len>
      <Hsp_qseq>RGRFGCVYRAQL---PGQEVAVKVF--PPEHKASWQN-----EVAMFTAAGMKHENLLQFLAAERRGTGLDFEFWIITLFQHKGSVGDYLKGNVVTWSELCHIA-ETMARGLSFLHEEGPDLKPAIAHRDFKSKNVLLKSDLTACVADLGLAVKFEPGKPPGDMH---GQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAVGLVMWELVS</Hsp_qseq>
      <Hsp_hseq>QGAFACVKNAHLQMDPSIILAVKFIHVPTCKKMGLSDKDITKEVVLQSKCS-KHPNVLRLIDCNVSKEYM----WIILEMADGGDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVEC-----GVAHRDIKPENILLDKNGNLKLADFGLASQFR--RKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYAD---RTDIWSIGILLFVLLT</Hsp_hseq>
      <Hsp_midline>+G F CV  A L   P   +AVK    P   K    +     EV + +    KH N+L+ +        +    WII      G + D ++ +V   S++     + +   +++LH E       +AHRD K +N+LL  +    +AD GLA +F   +  G +     Q G+  YMAPEVL     +  D   R D++++G++++ L++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>2.78066e-08</Hsp_evalue>
      <Hsp_query-from>733</Hsp_query-from>
      <Hsp_query-to>1221</Hsp_query-to>
      <Hsp_hit-from>134</Hsp_hit-from>
      <Hsp_hit-to>283</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>170</Hsp_align-len>
      <Hsp_qseq>EVAMFTAAGMKHENLLQFLAAERRGTGLDFEFWIITLFQHKGSVGDYLKGNVV--TWSELCHIAETMARGLSFLHEEGPDLKPAIAHRDFKSKNVLLKS-DLTACVADLGLAVKFEPGKPPGDMHGQVGTRRYMAPEVLEGAINFQ--RDAF--LRIDMYAVGLVMWELV</Hsp_qseq>
      <Hsp_hseq>EVDIQTKIG-RHQNIAALLDF--------FDSYIIMEYCSGGDLYEAIKADAVPKKTKSITHIITQIMDAIEYVHNKG------IYHRDIKPENILISGIDWTIKLTDWGLATTDKTS-----MDRNVGSERYMSPELFDSNLDIKERKEPYDCAKVDLWAMGIVFLNIV</Hsp_hseq>
      <Hsp_midline>EV + T  G +H+N+   L          F+ +II  +   G + + +K + V      + HI   +   + ++H +G      I HRD K +N+L+   D T  + D GLA   +       M   VG+ RYM+PE+ +  ++ +  ++ +   ++D++A+G+V   +V</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>4.18052e-08</Hsp_evalue>
      <Hsp_query-from>640</Hsp_query-from>
      <Hsp_query-to>1245</Hsp_query-to>
      <Hsp_hit-from>192</Hsp_hit-from>
      <Hsp_hit-to>383</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>209</Hsp_align-len>
      <Hsp_qseq>GRFGCVYRAQLPGQEVAVKVFPPEHKASWQNEVAMFTAAGMKHENLLQFL----AAERRGTGLDFEFWIITLFQHKGS--VGDYLKGNV-VTWSELCHIAETMARGLSFLHEEGPDLKPAIAHRDFKSKNVLLKSDLTACVADLGLAVKFEPGKPPGDMHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAVGLVMWELVSRCTVADG</Hsp_qseq>
      <Hsp_hseq>GTYGKVYKAKNTNTEKLVAL----KKLRLQGEREGFPITSIREIKLLQSFDHPNVSTIKEIMVESQKTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDN------KILHRDVKGSNILIDNQGNLKITDFGLARKMNSR---ADYTNRVITLWYRPPELLLGTTNYGTE----VDMWGCGCLLVELFNKTAIFQG</Hsp_hseq>
      <Hsp_midline>G +G VY+A+    E  V +     K   Q E   F    ++   LLQ       +  +   ++ +  +  +F++  +   G  L   V ++ S+  H+ + +  G+ +LH+        I HRD K  N+L+ +     + D GLA K        D   +V T  Y  PE+L G  N+  +    +DM+  G ++ EL ++  +  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>2.1136e-07</Hsp_evalue>
      <Hsp_query-from>760</Hsp_query-from>
      <Hsp_query-to>1494</Hsp_query-to>
      <Hsp_hit-from>60</Hsp_hit-from>
      <Hsp_hit-to>305</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>261</Hsp_align-len>
      <Hsp_qseq>MKHENLLQF---LAAERRGTGLDFEFWIITLFQHKGS--VGDYLKGNVVTWSELCHIAETMARGLSFLHEEGPDLKPAIAHRDFKSKNVLLKSDLTACVADLGLAVKFEPGKPPGDMHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAVGLVMWELVSRCTVADGPVGD--YRMPFEDEAGQH----PSLEDMQEVVVNKKQRPA--LRDCWRKH---PGLSQLCETVEECWDHDAEARLSAGCVVERVCHARRVAEAS</Hsp_qseq>
      <Hsp_hseq>LKHENIVRLYDVIHTENKLT-LVFEFMDNDLKKYMDSRTVGNTPRG--LELNLVKYFQWQLLQGLAFCHEN------KILHRDLKPQNLLINKRGQLKLGDFGLARAF--GIPVNTFSSEVVTLWYRAPDVLMGS----RTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPKYNPNIQQRPPRDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWFAEYYHHAS</Hsp_hseq>
      <Hsp_midline>+KHEN+++    +  E + T L FEF    L ++  S  VG+  +G  +  + + +    + +GL+F HE        I HRD K +N+L+       + D GLA  F  G P      +V T  Y AP+VL G+    R     ID+++ G ++ E+++   +  G   +   ++ F+     +    PS+  + +   N +QRP   LR   + H   P    L + +      + + RLSA   +     A     AS</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>2.77825e-07</Hsp_evalue>
      <Hsp_query-from>934</Hsp_query-from>
      <Hsp_query-to>1221</Hsp_query-to>
      <Hsp_hit-from>822</Hsp_hit-from>
      <Hsp_hit-to>919</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>108</Hsp_align-len>
      <Hsp_qseq>GLSFLHEEGPDLKPAIAHRDFKSKNVLLKSDLTACVADLGLA---------VKFEPGKPPG---DMHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAVGLVMWELV</Hsp_qseq>
      <Hsp_hseq>ALSYIHSQG------IIHRDLKPMNIFIDESRNVKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVLDGTGHYNE----KIDMYSLGIIFFEMI</Hsp_hseq>
      <Hsp_midline> LS++H +G      I HRD K  N+ +       + D GLA         +K +    PG   ++   +GT  Y+A EVL+G  ++      +IDMY++G++ +E++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>8.03136e-07</Hsp_evalue>
      <Hsp_query-from>877</Hsp_query-from>
      <Hsp_query-to>1434</Hsp_query-to>
      <Hsp_hit-from>310</Hsp_hit-from>
      <Hsp_hit-to>469</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>192</Hsp_align-len>
      <Hsp_qseq>KGNVVTWSELCHIAETMARGLSFLHEEGPDLKPAIAHRDFKSKNVLLKSDLTACVADLGLAVKFEPGKPPGDMHGQ-VGTRRYMAPEVLEGAINFQRDAFLRIDMYAVGLVMWELVSRCTVADGPVGDYRMPFE-DEAGQHPSLEDMQEVVVN----KKQRPALRDCWRKHPGLSQLCETVEECWDHDAEAR</Hsp_qseq>
      <Hsp_hseq>RGGRISERVIGKIAESVLRGLSYLHER------KVIHRDIKPQNILLNEKGEIKLCDFGVS-----GEAVNSLAMTFTGTSFYMAPERIQG-----QPYSVTCDVWSLGLTLLE------VAGG-----RFPFESDKITQNVAPIELLTMILTFSPQLKDEPELDISWSK-----TFRSFIDYCLKKDARER</Hsp_hseq>
      <Hsp_midline>+G  ++   +  IAE++ RGLS+LHE        + HRD K +N+LL       + D G++     G+    +     GT  YMAPE ++G     +   +  D++++GL + E      VA G     R PFE D+  Q+ +  ++  +++      K  P L   W K          ++ C   DA  R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>1.18534e-06</Hsp_evalue>
      <Hsp_query-from>676</Hsp_query-from>
      <Hsp_query-to>1263</Hsp_query-to>
      <Hsp_hit-from>36</Hsp_hit-from>
      <Hsp_hit-to>229</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>209</Hsp_align-len>
      <Hsp_qseq>GQEVAVKVFPPEHKASWQ----NEVAMFTAAGMKHENLLQFLAAERRGTGLDF-EFWIITLFQHKGSVGDYLKGNVVTWSELCHIAETMARGLSFLHEEGPDLKPAIAHRDFKSKNVLLKSDLTACVADLGLAVKFEP-----GKPPGDMHGQ---VGTRRYMAPEVLEGAINFQRDAFLRIDMYAVGLVMWELVSRCTVADGPVGDYR</Hsp_qseq>
      <Hsp_hseq>GEIVAIKKIEPFDKPLFALRTLREIKIL--KHFKHENIITIFNIQRPDSFENFNEVYIIQELM-QTDLHRVISTQMLSDDHIQYFIYQTLRAVKVLHGSN------VIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSR----AMDVWSCGCILAELFLRRPIFPG--RDYR</Hsp_hseq>
      <Hsp_midline>G+ VA+K   P  K  +      E+ +      KHEN++     +R  +  +F E +II     +  +   +   +++   + +      R +  LH         + HRD K  N+L+ S+    V D GLA   +       +P G   G    V TR Y APEV+  +  + R     +D+++ G ++ EL  R  +  G   DYR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YJR059W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:545787:548243:1 gene:YJR059W transcript:YJR059W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK2 description:Serine/threonine protein kinase; involved in regulation of ion transport across plasma membrane; carboxyl terminus is essential for glucose-dependent Pma1p activation via phosphorylation of Pma1p-Ser899; enhances spermine uptake; PTK2 has a paralog, PTK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003820]</Hit_def>
  <Hit_accession>YJR059W</Hit_accession>
  <Hit_len>818</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>2.19622e-06</Hsp_evalue>
      <Hsp_query-from>802</Hsp_query-from>
      <Hsp_query-to>1377</Hsp_query-to>
      <Hsp_hit-from>335</Hsp_hit-from>
      <Hsp_hit-to>521</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>208</Hsp_align-len>
      <Hsp_qseq>RGTGLDFEFWIITLFQHKGSVGDYLKGNVVTWSELCHIAETMARGLSFLHEEGPDLKPAIAHRDFKSKNVLLKSDLTACVADLGLA-----VKFEPGKPPGDMHGQVGTRRYMAPEVLE-GAINFQRDAF------LRIDMYAVGLVMWELVSRCTVADGPVGDYRMPFEDEAGQHPSLEDMQEVVVN--KKQRPALRD--CWRKHPG</Hsp_qseq>
      <Hsp_hseq>RGWGFIMELGVKDLFQLMERTG----WKNVPFNEKYCLFKQVAQGIKFCHDNG------IAHRDLKPENVLISKEGICKLTDFGISDWYHVIPHDYTSPVKTCQGMIGSPPYTPPEVMYFDAKKHYPEKFQKPYNPLAMDSYALGIMLITMINNI-----------IPFIDSCNTDARFREFEVSYDNFINHQNPHFRDKGCHKPGPG</Hsp_hseq>
      <Hsp_midline>RG G   E  +  LFQ     G       V ++E   + + +A+G+ F H+ G      IAHRD K +NVL+  +    + D G++     +  +   P     G +G+  Y  PEV+   A     + F      L +D YA+G+++  +++             +PF D         + +    N    Q P  RD  C +  PG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>2.9898e-06</Hsp_evalue>
      <Hsp_query-from>877</Hsp_query-from>
      <Hsp_query-to>1224</Hsp_query-to>
      <Hsp_hit-from>317</Hsp_hit-from>
      <Hsp_hit-to>417</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>117</Hsp_align-len>
      <Hsp_qseq>KGNVVTWSELCHIAETMARGLSFLHEEGPDLKPAIAHRDFKSKNVLLKSDLTACVADLGLAVKFEPGKPPGDMHGQ-VGTRRYMAPEVLEGAINFQRDAFLRIDMYAVGLVMWELVS</Hsp_qseq>
      <Hsp_hseq>RGGRISEKVLGKIAEAVLRGLSYLHEK------KVIHRDIKPQNILLNENGQVKLCDFGVS-----GEAVNSLATTFTGTSFYMAPERIQG-----QPYSVTSDVWSLGLTILEVAN</Hsp_hseq>
      <Hsp_midline>+G  ++   L  IAE + RGLS+LHE+       + HRD K +N+LL  +    + D G++     G+    +     GT  YMAPE ++G     +   +  D++++GL + E+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>4.78071e-06</Hsp_evalue>
      <Hsp_query-from>925</Hsp_query-from>
      <Hsp_query-to>1221</Hsp_query-to>
      <Hsp_hit-from>128</Hsp_hit-from>
      <Hsp_hit-to>211</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>99</Hsp_align-len>
      <Hsp_qseq>MARGLSFLHEEGPDLKPAIAHRDFKSKNVLLKSDLTACVADLGLAVKFEPGKPPGDMHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAVGLVMWELV</Hsp_qseq>
      <Hsp_hseq>ILRGLKYVHSAG------VIHRDLKPSNILINENCDLKICDFGLARIQDP-----QMTGYVSTRYYRAPEIM---LTWQKYD-VEVDIWSAGCIFAEMI</Hsp_hseq>
      <Hsp_midline>+ RGL ++H  G      + HRD K  N+L+  +    + D GLA   +P      M G V TR Y APE++   + +Q+   + +D+++ G +  E++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>5.15495e-06</Hsp_evalue>
      <Hsp_query-from>979</Hsp_query-from>
      <Hsp_query-to>1368</Hsp_query-to>
      <Hsp_hit-from>125</Hsp_hit-from>
      <Hsp_hit-to>254</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>IAHRDFKSKNVLLKSDLTACVADLGLAVKFEPGKPPGDMHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAVGLVMWELVSRCTVADGPVGDYRMPFEDEAGQHPSLEDMQEV----VVNKKQR--PALRDCWRK</Hsp_qseq>
      <Hsp_hseq>ILHRDLKPNNLLFSPDGQIKVADFGLARAIP--APHEILTSNVVTRWYRAPELLFGAKHYTS----AIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDRDWPEVSSFMTYNKLQIYPPPSRDELRK</Hsp_hseq>
      <Hsp_midline>I HRD K  N+L   D    VAD GLA       P   +   V TR Y APE+L GA ++       ID+++VG++  EL+ R     G     +M     A   P+  D  EV      NK Q   P  RD  RK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>5.66517e-06</Hsp_evalue>
      <Hsp_query-from>934</Hsp_query-from>
      <Hsp_query-to>1386</Hsp_query-to>
      <Hsp_hit-from>143</Hsp_hit-from>
      <Hsp_hit-to>291</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>163</Hsp_align-len>
      <Hsp_qseq>GLSFLHEEGPDLKPAIAHRDFKSKNVLLKSDLTACVADLGLAVKFEPGKPPGDMHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAVGLVMWELVS------------RCTVADGPVGDYRMPFEDEAGQHPSLEDMQEVVVNKKQRPALRDCWRKHPGLSQ</Hsp_qseq>
      <Hsp_hseq>GVSYCHALG------IVHRDLKPENLLLDHKYNIKIADFGMAALETEGKL---LETSCGSPHYAAPEIVSG-IPYQGFAS---DVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERRIKTRDIL-KHPLLQK</Hsp_hseq>
      <Hsp_midline>G+S+ H  G      I HRD K +N+LL       +AD G+A     GK    +    G+  Y APE++ G I +Q  A    D+++ G++++ L++            R  +     G++ MP +DE  +       + + V+ ++R   RD   KHP L +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>7.03201e-06</Hsp_evalue>
      <Hsp_query-from>979</Hsp_query-from>
      <Hsp_query-to>1284</Hsp_query-to>
      <Hsp_hit-from>173</Hsp_hit-from>
      <Hsp_hit-to>256</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>102</Hsp_align-len>
      <Hsp_qseq>IAHRDFKSKNVLLKSDLTACVADLGLAVKFEPGKPPGDMHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAVGLVMWELVSRCTVADGPVGDYRMPFEDEA</Hsp_qseq>
      <Hsp_hseq>IVHRDLKPENLLLDEHLNVKIADFGLSNIMTDG---NFLKTSCGSPNYAAPEVISGKLY----AGPEVDVWSCGVILYVMLCR-----------RLPFDDES</Hsp_hseq>
      <Hsp_midline>I HRD K +N+LL   L   +AD GL+     G     +    G+  Y APEV+ G +     A   +D+++ G++++ ++ R           R+PF+DE+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>7.76484e-06</Hsp_evalue>
      <Hsp_query-from>979</Hsp_query-from>
      <Hsp_query-to>1446</Hsp_query-to>
      <Hsp_hit-from>139</Hsp_hit-from>
      <Hsp_hit-to>305</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>171</Hsp_align-len>
      <Hsp_qseq>IAHRDFKSKNVLLKSDLTACVADLGLAVKFEPGKPP-----GDMHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAVGLVMWELVSRCTVADGPVGDYRMPFEDEAGQHPSLEDM--------QEVVVNKKQRPAL--RDCWRKHPGLSQLCETVEECWDHDAEARLSAG</Hsp_qseq>
      <Hsp_hseq>VIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIM---LTFQ-EYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIANLPMRPPLPWETVWSKTDLNPDMIDLLDKMLQFNPDKRISAA</Hsp_hseq>
      <Hsp_midline>+ HRD K  N+LL S+    V D GLA              G M   V TR Y APE++   + FQ +    +D+++ G ++ E+VS   +  G    +++    E    PS ED         +E + N   RP L     W K      + + +++    + + R+SA </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3329057830</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0051772-RA transcript Note:&quot;Protein of unknown function&quot; offset:1354 AED:0.14 eAED:0.14 QI:1354|0.85|0.87|1|0.71|0.5|8|2312|741</Iteration_query-def>
  <Iteration_query-len>5892</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>104</Statistics_hsp-len>
      <Statistics_eff-space>4143460620</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

