<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0056642-RA transcript Note:&quot;Similar to Hck Tyrosine-protein kinase HCK (Rattus norvegicus)&quot; offset:0 AED:0.23 eAED:0.23 QI:0|0.62|0.77|0.88|0.12|0.22|9|693|381</BlastOutput_query-def>
  <BlastOutput_query-len>1839</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056642-RA transcript Note:&quot;Similar to Hck Tyrosine-protein kinase HCK (Rattus norvegicus)&quot; offset:0 AED:0.23 eAED:0.23 QI:0|0.62|0.77|0.88|0.12|0.22|9|693|381</Iteration_query-def>
  <Iteration_query-len>1839</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>94.7449</Hsp_bit-score>
      <Hsp_score>234</Hsp_score>
      <Hsp_evalue>1.17058e-20</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>1086</Hsp_query-to>
      <Hsp_hit-from>68</Hsp_hit-from>
      <Hsp_hit-to>266</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>206</Hsp_align-len>
      <Hsp_qseq>LEEANLMKTLQHDKLVRLHAVVTDE-PIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEMVTFGRIPYPGMTNPEVIRSLERGYRMPKPDNCPCELYSIMQECWRQKPEERPTFEYL</Hsp_qseq>
      <Hsp_hseq>MAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRS-STGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSALTLAGT----LNWMAPEILGNRGASTLSDIWSLGATVVEMLT-KNPPYHNLTDANIYYAVENDTYYP-PSSFSEPLKDFLSKCFVKNMYKRPTADQL</Hsp_hseq>
      <Hsp_midline>+ E +L+K L H+ +V+ H  +     ++I+ EY   GSL   +  S  + L + +      Q   G+ ++  +  IHRD++AANIL++ +   K+ADFG++ I+  +  T        + W APE +     S  SD+WS G  + EM+T    PY  +T+  +  ++E     P P +    L   + +C+ +   +RPT + L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.5893</Hsp_bit-score>
      <Hsp_score>231</Hsp_score>
      <Hsp_evalue>1.9698e-20</Hsp_evalue>
      <Hsp_query-from>334</Hsp_query-from>
      <Hsp_query-to>1086</Hsp_query-to>
      <Hsp_hit-from>372</Hsp_hit-from>
      <Hsp_hit-to>639</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>132</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>276</Hsp_align-len>
      <Hsp_qseq>GGYFITSRITFHTLQE---LVVYYHRVYNKKTKVAVKMMKPGSM-APQAFLEEANLMKTLQHDKLVR-LHA-VVTDEPIFIVTEYMEKGSLLDFL----KTSEG---SRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKFPIK-WTAPEAINYGSFSIKSDVWSFGILLTEMVTFGRIPYPGMTNPEVIRSL-----ERGYRMPKPDNCPCELYSIMQECWRQKPEERP------TFEYL</Hsp_qseq>
      <Hsp_hseq>GAVYLSKRIKLPQENDPRFLKSHCHRVVGER--VAIKQIRLSEQPKKQLIMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFC--VELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIE-GEPPY---LNEDPLKALYLIANNGSPKLRHPESVSKQTKQFLDACLQVNVESRASVRKLLTFEFL</Hsp_hseq>
      <Hsp_midline>G  +++ RI      +   L  + HRV  ++  VA+K ++       Q  + E  +M   + + +V  L A ++ DE ++++ EYME G L D L    +++ G   S L + +M  +  +  +G+ F+ +K  IHRD+++ NIL+N   + KI DFG    +E  E  ++         W APE +N   +  K DVWS GI+L EM+  G  PY    N + +++L         ++  P++   +    +  C +   E R       TFE+L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>89.7373</Hsp_bit-score>
      <Hsp_score>221</Hsp_score>
      <Hsp_evalue>3.60358e-19</Hsp_evalue>
      <Hsp_query-from>421</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>590</Hsp_hit-from>
      <Hsp_hit-to>768</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>182</Hsp_align-len>
      <Hsp_qseq>KVAVKMMKPGSMAPQAFL--EEANLMKTLQHDKLVR-LHAVV-TDEPIFIVTEYMEKGSLLDFLKTS-----EGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEMVTFGRIPY</Hsp_qseq>
      <Hsp_hseq>KVAIKQMV-LSKQPRKELIVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPY-WMAPEVVKQREYDEKIDVWSLGIMTIEMLE-GEPPY</Hsp_hseq>
      <Hsp_midline>KVA+K M   S  P+  L   E  +MK  +H  +V  L A + TD+ +++V E+ME GSL D ++ S       S L +P++  +  +  +G+ F+ DK+ IHRD+++ N+L++     KI DFG    + D           P  W APE +    +  K DVWS GI+  EM+  G  PY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.8113</Hsp_bit-score>
      <Hsp_score>216</Hsp_score>
      <Hsp_evalue>1.30491e-18</Hsp_evalue>
      <Hsp_query-from>466</Hsp_query-from>
      <Hsp_query-to>1089</Hsp_query-to>
      <Hsp_hit-from>500</Hsp_hit-from>
      <Hsp_hit-to>708</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>215</Hsp_align-len>
      <Hsp_qseq>AFLEEANLMKTLQHDKLVRLHAVVTDEP-IFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARII-----EDNEYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEMVTFGRIPYPGMTNPEVIRSLERGYRMPKPDNCPCELYSIMQECWRQKPEERPT-FEYLQ</Hsp_qseq>
      <Hsp_hseq>ALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNY--GPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVF---WMSPEVVKQTATTAKADIWSTGCVVIEMFT-GKHPFPDFSQMQAIFKIGTNTTPEIPSWATSEGKNFLRKAFELDYQYRPSALELLQ</Hsp_hseq>
      <Hsp_midline>A   E NL+K L H+ +V  +    +   + I  EY+  GS+   L        ++  + +   Q+  G+A++  KN IHRD++ ANIL+++    KI DFG+++ +     + N+  + +G+ F   W +PE +   + + K+D+WS G ++ EM T G+ P+P  +  + I  +        P     E  + +++ +    + RP+  E LQ</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.2705</Hsp_bit-score>
      <Hsp_score>212</Hsp_score>
      <Hsp_evalue>5.69971e-18</Hsp_evalue>
      <Hsp_query-from>463</Hsp_query-from>
      <Hsp_query-to>1092</Hsp_query-to>
      <Hsp_hit-from>1223</Hsp_hit-from>
      <Hsp_hit-to>1436</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>226</Hsp_align-len>
      <Hsp_qseq>QAFLEEANLMKTLQHDKLVRLHAVVTDEPIF-IVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIED---NEYTAREGAKFPIKWTAPEAINYG-SFSIKSDVWSFGILLTEMVTFGRIPYPGMTNPEVIRSLERGYRMPKPDNCP------CELYS-----IMQECWRQKPEERPTFEYLQS</Hsp_qseq>
      <Hsp_hseq>EALRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMY--GRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVF---WMAPEMVDTKQGYSAKVDIWSLGCIVLEMFA-GKRPW---SNLEVVAAM---FKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANELLS</Hsp_hseq>
      <Hsp_midline>+A   E + +K L H  +V+         I+ +  EY+  GS+   ++     R  +P +  +  QV +G+A++  K  +HRD++A N+L++ + +CKI+DFG++R  +D   N      G  F   W APE ++    +S K D+WS G ++ EM   G+ P+   +N EV+ ++   +++ K  + P        L S      +  C+   PE+RPT   L S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.2629</Hsp_bit-score>
      <Hsp_score>199</Hsp_score>
      <Hsp_evalue>6.83603e-17</Hsp_evalue>
      <Hsp_query-from>427</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>115</Hsp_hit-from>
      <Hsp_hit-to>283</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>176</Hsp_align-len>
      <Hsp_qseq>AVKMMKPGSMAPQAFLEEAN----LMKTLQHDKLVRLHAVVTD-EPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEMVTFGRIPY</Hsp_qseq>
      <Hsp_hseq>ALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQ--RFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDY----IAPEVVSTKPYNKSVDWWSFGVLIYEMLA-GYTPF</Hsp_hseq>
      <Hsp_midline>A+K +K  ++     +E  N    ++  + H  ++R+     D + +F+V +Y+E G L   L+ S+  R   P      A+V   + ++  K+ I+RDL+  NIL++ N   KI DFG A+ + D  YT      +     APE ++   ++   D WSFG+L+ EM+  G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.337</Hsp_bit-score>
      <Hsp_score>194</Hsp_score>
      <Hsp_evalue>1.16268e-16</Hsp_evalue>
      <Hsp_query-from>394</Hsp_query-from>
      <Hsp_query-to>969</Hsp_query-to>
      <Hsp_hit-from>18</Hsp_hit-from>
      <Hsp_hit-to>219</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>211</Hsp_align-len>
      <Hsp_qseq>YHRVY---NKKTKV--AVKMMKPGS--MAPQAFLEEANLMKTLQHDKLVRLHAVV-TDEPIFIVTEYMEKGSLLDFLKTSEGSRL--KQPKMIDMCA------QVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARI--IEDNEYTAREGAKFPIKWTAPEAI-NYGSFSIKSDVWSFGILLTEMVTFGRIPYPGMTNPEVIR</Hsp_qseq>
      <Hsp_hseq>YATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDND-----LKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSE---VVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMIT-GKPLFPGTNDEEQLK</Hsp_hseq>
      <Hsp_midline>Y  VY   NK T V  A+K +K  S    P   + E +LMK L+H+ +VRL+ V+ T+  + +V E+M+       LK    SR     P+ +++        Q+ +G+AF  +   +HRDL+  N+L+N     K+ DFGLAR   I  N +++       + + AP+ +    ++S   D+WS G +L EM+T G+  +PG  + E ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.6481</Hsp_bit-score>
      <Hsp_score>200</Hsp_score>
      <Hsp_evalue>1.35726e-16</Hsp_evalue>
      <Hsp_query-from>469</Hsp_query-from>
      <Hsp_query-to>1110</Hsp_query-to>
      <Hsp_hit-from>662</Hsp_hit-from>
      <Hsp_hit-to>870</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>222</Hsp_align-len>
      <Hsp_qseq>FLEEANLMKTLQHDKLVR-LHAVVTDEPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGL-ARIIEDN-EYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEMVTFGRIPYPGMTNPEVIRSL-----ERGYRMPKPDNCPCELYSIMQECWRQKPEERPTFEYLQSLLEDFY</Hsp_qseq>
      <Hsp_hseq>IINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVT---HCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTMVGTPY---WMAPEVVSRKEYGPKVDIWSLGIMIIEMIE-GEPPY---LNETPLRALYLIATNGTPKLKEPENLSSSLKKFLDWCLCVEPEDRAS---ATELLHDEY</Hsp_hseq>
      <Hsp_midline> + E  +MK  +H  +V  + + V    ++++ EYME GSL D +       L + ++  +C +   G+ F+  K  +HRD+++ NIL+++    K+ DFG  A+I E N + T   G  +   W APE ++   +  K D+WS GI++ EM+  G  PY    N   +R+L         ++ +P+N    L   +  C   +PE+R +      LL D Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.4925</Hsp_bit-score>
      <Hsp_score>197</Hsp_score>
      <Hsp_evalue>2.05598e-16</Hsp_evalue>
      <Hsp_query-from>463</Hsp_query-from>
      <Hsp_query-to>936</Hsp_query-to>
      <Hsp_hit-from>263</Hsp_hit-from>
      <Hsp_hit-to>421</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>163</Hsp_align-len>
      <Hsp_qseq>QAFLEEANLMKTLQHDKLVRLHAVVTDE---PIFIVTEYMEKGSLLDFLKT--SEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEMVTFGRIP</Hsp_qseq>
      <Hsp_hseq>KQIFRELQFNRSFQSEYIVRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVSGEAVNSLATTFTGTSF---YMAPERIQGQPYSVTSDVWSLGLTILE-VANGKFP</Hsp_hseq>
      <Hsp_midline>+    E    ++ Q + +VR + + TD+    I+I  EYM   SL    K     G R+ +  +  +   V  G++++ +K  IHRD++  NIL+N N   K+ DFG++    ++  T   G  F   + APE I    +S+ SDVWS G+ + E V  G+ P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.337</Hsp_bit-score>
      <Hsp_score>194</Hsp_score>
      <Hsp_evalue>2.25274e-16</Hsp_evalue>
      <Hsp_query-from>475</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>134</Hsp_hit-from>
      <Hsp_hit-to>282</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>156</Hsp_align-len>
      <Hsp_qseq>EEANLMKTLQHDKLVRLHAVVTD-EPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEMVTFGRIPY</Hsp_qseq>
      <Hsp_hseq>DERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQ--RFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTL---CGTP-DYIAPEVVSTKPYNKSIDWWSFGILIYEMLA-GYTPF</Hsp_hseq>
      <Hsp_midline>+E  ++  + H  ++R+     D + IF++ +Y+E G L   L+ S+  R   P      A+V   + ++  K+ I+RDL+  NIL++ N   KI DFG A+ + D  YT       P  + APE ++   ++   D WSFGIL+ EM+  G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.9518</Hsp_bit-score>
      <Hsp_score>193</Hsp_score>
      <Hsp_evalue>2.65235e-16</Hsp_evalue>
      <Hsp_query-from>427</Hsp_query-from>
      <Hsp_query-to>981</Hsp_query-to>
      <Hsp_hit-from>97</Hsp_hit-from>
      <Hsp_hit-to>298</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>208</Hsp_align-len>
      <Hsp_qseq>AVKMMKPGSMAPQAFLEEAN----LMKTLQHDKLVRLHAVVTD-EPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEM------------------VTFGRIPYPGMTNPEVIRSLER</Hsp_qseq>
      <Hsp_hseq>AIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQ--RFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTPDY----IAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSK</Hsp_hseq>
      <Hsp_midline>A+K++K   +     +E  N    ++K ++H  L+R+     D   IF+V +Y+E G L   L+ S+  R   P      A+V   + ++   N I+RDL+  NIL++ N   KI DFG A+ ++   +T      +     APE I    ++   D WS G+L+ EM                  +  G++ YP   +P+V+  L +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.337</Hsp_bit-score>
      <Hsp_score>194</Hsp_score>
      <Hsp_evalue>4.09888e-16</Hsp_evalue>
      <Hsp_query-from>400</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>232</Hsp_hit-from>
      <Hsp_hit-to>415</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>188</Hsp_align-len>
      <Hsp_qseq>RVYNKKTKVAVKMMKPGSMAPQ---AFLEEANLMKTLQHDKLVRLHAVVTDE---PIFIVTEYMEKGSLLDFLKT--SEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEMVTFGRIPY</Hsp_qseq>
      <Hsp_hseq>RLKNGKKVFALKTINTMNTDPEYQKQIFRELQFNKSFKSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFGVSGEAVNSLAMTFTGTSF---YMAPERIQGQPYSVTCDVWSLGLTLLE-VAGGRFPF</Hsp_hseq>
      <Hsp_midline>R+ N K   A+K +   +  P+       E    K+ + D +V+ + + TDE    I+I  EYM   SL    K     G R+ +  +  +   V  G++++ ++  IHRD++  NIL+N     K+ DFG++    ++      G  F   + APE I    +S+  DVWS G+ L E V  GR P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.9518</Hsp_bit-score>
      <Hsp_score>193</Hsp_score>
      <Hsp_evalue>4.77007e-16</Hsp_evalue>
      <Hsp_query-from>433</Hsp_query-from>
      <Hsp_query-to>945</Hsp_query-to>
      <Hsp_hit-from>53</Hsp_hit-from>
      <Hsp_hit-to>219</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>182</Hsp_align-len>
      <Hsp_qseq>KMMKPGSMAPQA--FLEEANLMKTLQHDKLVRLHAVVTD--EPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMID------MCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPE-AINYGSFSIKSDVWSFGILLTEMVTFGRIPYPG</Hsp_qseq>
      <Hsp_hseq>KIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLSPLEDIYFVTE----------LQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLAR-IQDPQMTGYVSTRY---YRAPEIMLTWQKYDVEVDIWSAGCIFAEMIE-GKPLFPG</Hsp_hseq>
      <Hsp_midline>K+MKP S A  A     E  L+K L+H+ L+ L  +     E I+ VTE          L+ ++  RL Q + ++         Q+  G+ ++     IHRDL+ +NIL+N N   KI DFGLAR I+D + T     ++   + APE  + +  + ++ D+WS G +  EM+  G+  +PG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.337</Hsp_bit-score>
      <Hsp_score>194</Hsp_score>
      <Hsp_evalue>7.70928e-16</Hsp_evalue>
      <Hsp_query-from>448</Hsp_query-from>
      <Hsp_query-to>1068</Hsp_query-to>
      <Hsp_hit-from>67</Hsp_hit-from>
      <Hsp_hit-to>277</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>218</Hsp_align-len>
      <Hsp_qseq>GSMAPQAF----LEEANLMKTLQHDKLVRLHAV-VTDEPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPE---AINYGSFSIKSDVWSFGILLTEMVTFGRIPY---PGMTNPEVIRSLERGYRMPKPDNCPCELYSIMQECWRQKPEER</Hsp_qseq>
      <Hsp_hseq>GSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLL--VERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAAL--ETEGKLLETSCGSPHYAAPEIVSGIPYQGFA--SDVWSCGVILFALLT-GRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERR</Hsp_hseq>
      <Hsp_midline>GS  P A       E  +MK L H  ++RL+ V  T+  +++V EY EKG L + L   E   L + + I    Q+  G+++      +HRDL+  N+L++     KIADFG+A +  + E    E +     + APE    I Y  F+  SDVWS G++L  ++T GR+P+    G     +++  +  + MP  D    E   ++++     PE R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.6406</Hsp_bit-score>
      <Hsp_score>187</Hsp_score>
      <Hsp_evalue>4.53468e-15</Hsp_evalue>
      <Hsp_query-from>349</Hsp_query-from>
      <Hsp_query-to>1086</Hsp_query-to>
      <Hsp_hit-from>352</Hsp_hit-from>
      <Hsp_hit-to>617</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>125</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>275</Hsp_align-len>
      <Hsp_qseq>TSRITFHTLQELVVYYHRVYNKKTKVAVKMMKPGS--MAPQAF---LEEANLMKTLQHDKLVRLH------------AVVTDEPIFIVTEYMEKGSLLD-FLKTSEGSRLKQPKMIDMCAQVAEGMAFI-EDKNYIHRDLRAANILVNVNL-VCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAI-----NYGSFSIKSDVWSFGILLTEMVTFGRIPYPGMTNPEVIRSLERGYRMPKP----DNCPCELYSIMQECWRQKPEERPTFEYL</Hsp_qseq>
      <Hsp_hseq>SSRITLDELEFLDELGHGNYGNVSKV---LHKPTNVIMATKEVRLELDEAKFRQILM--ELEVLHKCNSPYIVDFYGAFFIEGAVYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSANQGTVKLCDFGVSGNLVASLAKTNIGCQ---SYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMA-LGRYPYPPETYDNIFSQLSAIVDGPPPRLPSDKFSSDAQDFVSLCLQKIPERRPTYAAL</Hsp_hseq>
      <Hsp_midline>+SRIT   L+ L    H  Y   +KV   + KP +  MA +     L+EA   + L   +L  LH            A   +  +++  EYM+ GSL   + ++SE   + +P++  +   V  G+  + E  N IHRD++  NIL + N    K+ DFG++  +  +      G +    + APE I     +  +++++SD+WS G+ + EM   GR PYP  T   +   L      P P    D    +    +  C ++ PE RPT+  L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.485</Hsp_bit-score>
      <Hsp_score>184</Hsp_score>
      <Hsp_evalue>1.28607e-14</Hsp_evalue>
      <Hsp_query-from>475</Hsp_query-from>
      <Hsp_query-to>1074</Hsp_query-to>
      <Hsp_hit-from>1082</Hsp_hit-from>
      <Hsp_hit-to>1300</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>223</Hsp_align-len>
      <Hsp_qseq>EEANLMKTLQHDKLVRLHAV-VTDEPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCA-QVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLAR-IIEDNEYTAREGA--KFPIK------------WTAPEAINYGSFSIK---SDVWSFGILLTEMVTFGRIPYPGMTNPEVIR---SLERGYRMPKPDNCPCELYSIMQECWRQKPEERPT</Hsp_qseq>
      <Hsp_hseq>EEMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEYCEGGSLASLL---DHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMAT-GRRPWSNLDNEWAIMYHVAAGRIPQLPNRDEMTAAGRAFLERCLVQDPTMRAT</Hsp_hseq>
      <Hsp_midline>EE  +++ L H  +V+ + V V  + + I  EY E GSL   L   +  R++   +  +   ++ EG+A++     +HRD++  NIL++ N + K  DFG AR ++     T R  A   F ++            + APE I+  +   K    DVW+ G ++ EM T GR P+  + N   I    +  R  ++P  D       + ++ C  Q P  R T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.559</Hsp_bit-score>
      <Hsp_score>179</Hsp_score>
      <Hsp_evalue>4.20541e-14</Hsp_evalue>
      <Hsp_query-from>463</Hsp_query-from>
      <Hsp_query-to>1077</Hsp_query-to>
      <Hsp_hit-from>124</Hsp_hit-from>
      <Hsp_hit-to>328</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>209</Hsp_align-len>
      <Hsp_qseq>QAFLEEANLMKTLQHDKLVR-LHAVVTDEPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAI--NYGSFSIKSDVWSFGILLTEMVTFGRIPYPGMTNPEVIRSLE-RGYRMPKPDNCPCELYSIMQECWRQKPEERPTF</Hsp_qseq>
      <Hsp_hseq>KKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRK--VLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLA-NESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALL-IGKPPFQARDVNTIYERIKCRDFSFPRDKPISDEGKILIRDILSLDPIERPSL</Hsp_hseq>
      <Hsp_midline>+  L E  + K++ H  +V+ +     D  ++I+ E    GSL++ LK  +   L +P++     Q+   + ++  +  IHRDL+  NI  + N   KI DFGLA ++  NE   +        + APE +   +   S + D+WS G++L  ++  G+ P+       +   ++ R +  P+      E   ++++     P ERP+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>1.0048e-13</Hsp_evalue>
      <Hsp_query-from>460</Hsp_query-from>
      <Hsp_query-to>915</Hsp_query-to>
      <Hsp_hit-from>52</Hsp_hit-from>
      <Hsp_hit-to>205</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>161</Hsp_align-len>
      <Hsp_qseq>PQAFLEEANLMKTLQHDKLVRLHAVVTDEP--IFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCA----QVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARI--IEDNEYTAREGAKFPIKWTAPEAINYG-SFSIKSDVWSFGILLTEM</Hsp_qseq>
      <Hsp_hseq>PSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLD----LDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHE---IVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEM</Hsp_hseq>
      <Hsp_midline>P   + E +L+K L+ D +VRL+ +V  +   +++V E+++    LD  +  EG    QP   D+      Q+ +G+A+      +HRDL+  N+L+N +   K+ DFGLAR   +    YT        + + APE +  G  +S   D WS G +  EM</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>1.67394e-13</Hsp_evalue>
      <Hsp_query-from>451</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>68</Hsp_hit-from>
      <Hsp_hit-to>227</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>167</Hsp_align-len>
      <Hsp_qseq>SMAPQAFLEEANLMKTLQHDKLVRLHAV-VTDEPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAIN---YGSFSIKSDVWSFGILLTEMVTFGRIPY</Hsp_qseq>
      <Hsp_hseq>SVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLL--VDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLL--ETSCGSPHYAAPEIVSGLPYEGFA--SDVWSCGVILFALLT-GRLPF</Hsp_hseq>
      <Hsp_midline>S+ P     E  +MK L H  ++ L+ V  T+  ++++ EY EKG L + L   +   L + + I+   Q+  G+++      +HRDL+  N+L++     KIADFG+A +  D +    E +     + APE ++   Y  F+  SDVWS G++L  ++T GR+P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>1.8317e-13</Hsp_evalue>
      <Hsp_query-from>334</Hsp_query-from>
      <Hsp_query-to>999</Hsp_query-to>
      <Hsp_hit-from>53</Hsp_hit-from>
      <Hsp_hit-to>273</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>118</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>229</Hsp_align-len>
      <Hsp_qseq>GGYFITSRITFHTLQELVVYYHRVYNKKTKVAVKMMKPGSMAP---QAFLE-EANLMKTLQHDKLVRLHAVV-TDEPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINYGSFS-IKSDVWSFGILLTEMVTFGRIPYPGMTNPEVIRSLERG-YRMPK</Hsp_qseq>
      <Hsp_hseq>GNYQIVKTLGEGSFGKVKLAYHTTTGQK--VALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYI--VQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFL-KTSCGSP-NYAAPEVISGKLYAGPEVDVWSCGVILYVMLC-RRLPFDDESIPVLFKNISNGVYTLPK</Hsp_hseq>
      <Hsp_midline>G Y I   +   +  ++ + YH    +K  VA+K++    +A    Q  +E E + ++ L+H  +++L+ V+ + + I +V EY     L D++   +  ++ + +      Q+   + +      +HRDL+  N+L++ +L  KIADFGL+ I+ D  +  +     P  + APE I+   ++  + DVWS G++L  M+   R+P+   + P + +++  G Y +PK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>2.30216e-13</Hsp_evalue>
      <Hsp_query-from>475</Hsp_query-from>
      <Hsp_query-to>1074</Hsp_query-to>
      <Hsp_hit-from>1314</Hsp_hit-from>
      <Hsp_hit-to>1548</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>43</Hsp_gaps>
      <Hsp_align-len>239</Hsp_align-len>
      <Hsp_qseq>EEANLMKTLQHDKLVRLHAV-VTDEPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDM-CAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDN---------------------------EYTAREGAKFPIKWT----APEAINYGSFSIK---SDVWSFGILLTEMVTFGRIPYPGMTNP-EVIRSLERGY--RMPKPDNCPCELYSIMQECWRQKPEERPT</Hsp_qseq>
      <Hsp_hseq>EEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAALL---EHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMIT-GRRPWANLDNEWAIMYHVAAGHTPQFPTKDEVSSAGMKFLERCLIQNPSKRAS</Hsp_hseq>
      <Hsp_midline>EE ++++ L H  +V  + V V  + + I  EY E GSL   L   E  R++   +  +   Q+ EG+A++ +   +HRD++  NIL++ N V K  DFG A+ I +N                                E A   +  T    APE+I   +   K    DVWS G ++ EM+T GR P+  + N   ++  +  G+  + P  D         ++ C  Q P +R +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>4.35539e-13</Hsp_evalue>
      <Hsp_query-from>523</Hsp_query-from>
      <Hsp_query-to>1095</Hsp_query-to>
      <Hsp_hit-from>80</Hsp_hit-from>
      <Hsp_hit-to>275</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>201</Hsp_align-len>
      <Hsp_qseq>LHAVVTDEPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAI--NYGSFSIKSDVWSFGILLTEMVTFGRIPYPGMTNPEVIRSLERGYRMPKPDNCPCE--LYSIMQECWRQKPEERP------TFEYLQSL</Hsp_qseq>
      <Hsp_hseq>IATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRST--LKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLK-GLPPLSKYDPMKVMTNLPK--RKPPKLQGPFSDAAKDFVAGCLVKTPADRPSAYNLLSFEFVKNI</Hsp_hseq>
      <Hsp_midline>+  ++ D  ++IV EY   GS  D LK S  + L + K+  +  +V  G+ ++ ++  IHRD++AANIL+N   + K+ DFG++  I       R+       W APE +      ++ K+D+WS GI   E++  G  P       +V+ +L +  R P     P        +  C  + P +RP      +FE+++++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>4.39344e-13</Hsp_evalue>
      <Hsp_query-from>397</Hsp_query-from>
      <Hsp_query-to>1080</Hsp_query-to>
      <Hsp_hit-from>42</Hsp_hit-from>
      <Hsp_hit-to>317</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>54</Hsp_gaps>
      <Hsp_align-len>279</Hsp_align-len>
      <Hsp_qseq>HRVYNKKTKVAVKMMKPGSMAPQAFLE----EANLMKTLQHDKLVRL-HAVVTDEPIFIVTEYMEKGSLLDFLK----------------------TSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLV---------------------CKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEMVTFGRIPYPGMTNPEVIRSLERG---YRMPKPDNCPCELYSIMQECWRQKPEERPTFE</Hsp_qseq>
      <Hsp_hseq>HLTSDKSQHVAIKEVSRAKLKNKKLLENLEIEIAILKKIKHPHIVGLIDCERTSTDFYLIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLP-NTSLAETLCGSPL-YMAPEILNYQKYNAKADLWSVGTVVFEMCC-GTPPFRASNHLELFKKIKRANDVITFPSYCNIEPELKELICSLLTFDPAQRIGFE</Hsp_hseq>
      <Hsp_midline>H   +K   VA+K +    +  +  LE    E  ++K ++H  +V L     T    +++ EY   G L   LK                      +   + L +  ++    Q+A  + F+  KN +HRD++  N+L++  L+                      KIADFG AR +  N   A      P+ + APE +NY  ++ K+D+WS G ++ EM   G  P+    + E+ + ++R       P   N   EL  ++       P +R  FE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>4.44567e-13</Hsp_evalue>
      <Hsp_query-from>409</Hsp_query-from>
      <Hsp_query-to>906</Hsp_query-to>
      <Hsp_hit-from>219</Hsp_hit-from>
      <Hsp_hit-to>411</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>198</Hsp_align-len>
      <Hsp_qseq>NKKT--KVAVKMMKPGSMAPQ----AFLEEANLMKTLQHDKLVRLHAVVTDEPI-------FIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVN-------------------VNLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILL</Hsp_qseq>
      <Hsp_hseq>NKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFV-EPISKSQIQKYLVLEKIDDGEL--FERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCG--TPSYVAPEVLTKKGYTSKVDLWSAGVIL</Hsp_hseq>
      <Hsp_midline>NKKT  +VAVK+        Q     F EE N++  +QH  +V L      EPI       ++V E ++ G L  F +    + L+Q +   +  Q+  G+ ++ ++N IHRD++  NIL+N                   +++  KIADFGLA+   + ++T          + APE +    ++ K D+WS G++L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>6.65083e-13</Hsp_evalue>
      <Hsp_query-from>397</Hsp_query-from>
      <Hsp_query-to>945</Hsp_query-to>
      <Hsp_hit-from>83</Hsp_hit-from>
      <Hsp_hit-to>287</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>210</Hsp_align-len>
      <Hsp_qseq>HRVYNKKTK--VAVKMMKPGSMAPQAFL---EEANLMKTLQHDKLVRLHAVVTDE---PIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNV-----------------NLVCKIADFGLARIIED-NEYTAREGAKFPIKWTAPEA-INYGSFSIKSDVWSFGILLTEMVTFGRIPYPG</Hsp_qseq>
      <Hsp_hseq>HQNYITKTQGVVAIKTMMTKLHTLQDYTRVREIKFILAIPANDHLIQIFEVFIDSENYQLHIVMECMEQ-NLYQMMKHRRRRVFSIPSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVENKNPYTAYVSTRW---YRSPEILLRSGYYSKPLDIWAFGCVAVEVTVF-RALFPG</Hsp_hseq>
      <Hsp_midline>H+ Y  KT+  VA+K M       Q +    E   ++    +D L+++  V  D     + IV E ME+ +L   +K         P +  + +Q+  G+  I + N+ HRDL+  NIL+                   N V K+ADFGLAR +E+ N YTA    ++   + +PE  +  G +S   D+W+FG +  E+  F R  +PG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>8.91543e-13</Hsp_evalue>
      <Hsp_query-from>463</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>147</Hsp_hit-from>
      <Hsp_hit-to>301</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>164</Hsp_align-len>
      <Hsp_qseq>QAFLEEANLMKTLQHDKLVRLHAVVTDEP-IFIVTEYMEKGSLLDFLKTSEGSRLKQP----KMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEMVTFGRIPY</Hsp_qseq>
      <Hsp_hseq>KQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLL------RLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWS-IINPPE-NRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLT-GAPPF</Hsp_hseq>
      <Hsp_midline>+ F  E  +  +L H  L + +    DE  ++++ EY+  G +   L      RL  P       D   Q+A  + ++  KN IHRD++  NIL+  N V K+ DFG + II   E   R+     I + +PE +    +    D W+ G+L  E++T G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>1.51337e-12</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>1086</Hsp_query-to>
      <Hsp_hit-from>192</Hsp_hit-from>
      <Hsp_hit-to>392</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>213</Hsp_align-len>
      <Hsp_qseq>LEEANLMKTLQHDKLVRLHAVVT-DEPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTARE------GAKFPIKWTAPEAINYGSFS-IKSDVWSFGILLTEMVTFGRIPYPGMTNPEVIRSLERGYRMPKPDNCPCELYSIMQECWRQKPEERPTFEYL</Hsp_qseq>
      <Hsp_hseq>IREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYI-IQHGS-IREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNI-----YDSRKQLHTFCGSLY---FAAPELLKANPYTGPEVDVWSFGVVLFVLVC-GKVPFDDENSSVLHEKIKQG-KVEYPQHLSIEVISLLSKMLVVDPKRRATLKQV</Hsp_hseq>
      <Hsp_midline>+ EA+L + L H  + RL  + T     +++ EY+  G LLD++    GS +++ +       +A  + ++   N +HRDL+  NI+++ +   KI DFGL+ I     Y +R+      G+ +   + APE +    ++  + DVWSFG++L  +V  G++P+    +  +   +++G ++  P +   E+ S++ +     P+ R T + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>2.50077e-12</Hsp_evalue>
      <Hsp_query-from>385</Hsp_query-from>
      <Hsp_query-to>1074</Hsp_query-to>
      <Hsp_hit-from>60</Hsp_hit-from>
      <Hsp_hit-to>299</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>244</Hsp_align-len>
      <Hsp_qseq>VVYYHRVYNKKTKVAVKMM-----KPGSMAPQAFLEEANLMKTLQHDKLVRLHA-VVTDEPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILV---NVNLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEMVTFGRIPY-----PGMTNPEVIRSLERGYRMPKPDNCPCELYSIMQECWRQKPEERPT</Hsp_qseq>
      <Hsp_hseq>VVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRI-LSRG-KFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAG-SLGYVAPEVLTQDGHGKPCDIWSIGV-ITYTLLCGYSPFIAESVEGFMEECTASRYPVTFHMPYWDNISIDVKRFILKALRLNPADRPT</Hsp_hseq>
      <Hsp_midline>VV   R  +    VA+K++     +  ++  Q   EE ++++ L H  +V       + +  +IVT+    G L D +  S G +  +   +++  Q+   + ++  KN +HRDL+  N+L    + N    IADFG+A+ ++  E    + A   + + APE +         D+WS G+ +T  +  G  P+      G             + MP  DN   ++   + +  R  P +RPT</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>3.2255e-12</Hsp_evalue>
      <Hsp_query-from>460</Hsp_query-from>
      <Hsp_query-to>1086</Hsp_query-to>
      <Hsp_hit-from>158</Hsp_hit-from>
      <Hsp_hit-to>363</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>213</Hsp_align-len>
      <Hsp_qseq>PQAFLEEANLMKTLQHDKLVRLHAVVTDEP-IFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVN-VNLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINYGSF-SIKSDVWSFGILLTEMVTFGRIPYPGMTNPEVIRSLERG-YRMPKPDNCPCELYSIMQECWRQKPEERPTFEYL</Hsp_qseq>
      <Hsp_hseq>PYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYL-VSKG-KLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKL-LKTSCGSP-HYASPEIVMGRPYHGGPSDVWSCGIVLFALLT-GHLPFNDDNIKKLLLKVQSGKYQM--PSNLSSEARDLISKILVIDPEKRITTQEI</Hsp_hseq>
      <Hsp_midline>P     E  +MK + H  ++ L  V  ++  +++V EY++ G L D+L  S+G +L + + I    Q+ EG+++    N  HRDL+  N+L++  N   KIADFG+A +   N+   +     P  + +PE +    +    SDVWS GI+L  ++T G +P+      +++  ++ G Y+M  P N   E   ++ +     PE+R T + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>5.31072e-12</Hsp_evalue>
      <Hsp_query-from>478</Hsp_query-from>
      <Hsp_query-to>1002</Hsp_query-to>
      <Hsp_hit-from>244</Hsp_hit-from>
      <Hsp_hit-to>429</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>191</Hsp_align-len>
      <Hsp_qseq>EANLMKTLQHDKLVRLHAVVTD-EPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVN--LVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINYGSFSIKS-------------DVWSFGILLTEMVTFGRIPYPGMTNPEVIRSLERGYRMPKP</Hsp_qseq>
      <Hsp_hseq>ELEVLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFV-AAHGA-VGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMKTFCG--TLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILT-GHLPFSGSTQDQLYKQIGRGSYHEGP</Hsp_hseq>
      <Hsp_midline>E  +++ L H ++VRL     D E  ++V E++  G L+DF+  + G+ + +    ++  Q+   + +I      HRDL+  NIL+  +  ++ KI DFGLA++  +  +         + + APE I     S+               D+WS G L+  ++T G +P+ G T  ++ + + RG     P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>9.08648e-12</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>171</Hsp_hit-from>
      <Hsp_hit-to>323</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>159</Hsp_align-len>
      <Hsp_qseq>LEEANLMKTLQHDKLVRLHAVVT-DEPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIE-DNEYTAREGAKFPIKWTAPEAINYGSFS-IKSDVWSFGILLTEMVTFGRIPY</Hsp_qseq>
      <Hsp_hseq>VREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYI-IQHGS-LKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYRKQLHTFCGSLY---FAAPELLKAQPYTGPEVDIWSFGIVLYVLVC-GKVPF</Hsp_hseq>
      <Hsp_midline>+ EA+L + L H  + RL  + T     +++ EY+  G LLD++    GS LK+         +A  + ++   N +HRDL+  NI+++ +   KI DFGL+ I +   +     G+ +   + APE +    ++  + D+WSFGI+L  +V  G++P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YNL020C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:595623:597539:-1 gene:YNL020C transcript:YNL020C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ARK1 description:Serine/threonine protein kinase; involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis; ARK1 has a paralog, PRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004965]</Hit_def>
  <Hit_accession>YNL020C</Hit_accession>
  <Hit_len>638</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>1.34469e-11</Hsp_evalue>
      <Hsp_query-from>550</Hsp_query-from>
      <Hsp_query-to>1074</Hsp_query-to>
      <Hsp_hit-from>105</Hsp_hit-from>
      <Hsp_hit-to>288</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>188</Hsp_align-len>
      <Hsp_qseq>IFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIE--DKNYIHRDLRAANILVNVNLVCKIADFGLA-------RIIEDNEYTAREGAK-FPIKWTAPEAIN-YGSFSI--KSDVWSFGILLTEMVTFGRIPYPGMTNPEVIRSLERGYRMPKPDNCPCELYSIMQECWRQKPEERPT</Hsp_qseq>
      <Hsp_hseq>VFVLMEYCERGGLIDFMNTRLQNRLHEFEILQIMSQVTQGVAAMHALQPPLIHRDIKIENVLISANNEYKLCDFGSVCGIIRPPRNSQELSYVQQDILKNTTAQYRSPEMIDTFRGLPIDEKSDIWALGIFLYKLCYY-TTPFEKGGDLAI---LSGKFEFPLYPNYSEQLKGLIRDILVQDPRHRPN</Hsp_hseq>
      <Hsp_midline>+F++ EY E+G L+DF+ T   +RL + +++ + +QV +G+A +       IHRD++  N+L++ N   K+ DFG         R  ++  Y  ++  K    ++ +PE I+ +    I  KSD+W+ GI L ++  +   P+    +  +   L   +  P   N   +L  ++++   Q P  RP </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>1.71377e-11</Hsp_evalue>
      <Hsp_query-from>424</Hsp_query-from>
      <Hsp_query-to>945</Hsp_query-to>
      <Hsp_hit-from>39</Hsp_hit-from>
      <Hsp_hit-to>225</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>193</Hsp_align-len>
      <Hsp_qseq>VAVKMMKPGSMAPQAF--LEEANLMKTLQHDKLVRLHAVVTDEP------IFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARII-----EDNEYTAREGAK---FPIKW-TAPEA-INYGSFSIKSDVWSFGILLTEMVTFGRIP-YPG</Hsp_qseq>
      <Hsp_hseq>VAIKKIEPFDKPLFALRTLREIKILKHFKHENIITIFNIQRPDSFENFNEVYIIQELMQT----DLHRVISTQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAEL--FLRRPIFPG</Hsp_hseq>
      <Hsp_midline>VA+K ++P      A   L E  ++K  +H+ ++ +  +   +       ++I+ E M+     D  +      L    +     Q    +  +   N IHRDL+ +N+L+N N   K+ DFGLARII     +++E T ++         +W  APE  +    +S   DVWS G +L E+  F R P +PG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>5.50924e-11</Hsp_evalue>
      <Hsp_query-from>421</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>76</Hsp_hit-from>
      <Hsp_hit-to>252</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>182</Hsp_align-len>
      <Hsp_qseq>KVAVKMMKPGSMAPQAFLE-----EANLMKTLQHDKLVRLHAVVTDEP-IFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLAR-IIEDNEYTAREGAKFPIKWTAPEAI--NYGSFSIKSDVWSFGILLTEMVTFGRIPY</Hsp_qseq>
      <Hsp_hseq>QVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKR--RLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNEL-MKTSCGSPC-YAAPELVVSTKAYEARKADVWSCGVILYAMLA-GYLPW</Hsp_hseq>
      <Hsp_midline>+VA+K+++  ++   A  E     E N +K L H  ++ L  V+ +   I IV E++  G    +++     RLK+     + AQ+  G+ ++  K  +HRDL+  N+L++ +    I DFG      EDNE   +     P  + APE +       + K+DVWS G++L  M+  G +P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>5.79396e-11</Hsp_evalue>
      <Hsp_query-from>421</Hsp_query-from>
      <Hsp_query-to>960</Hsp_query-to>
      <Hsp_hit-from>76</Hsp_hit-from>
      <Hsp_hit-to>260</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>194</Hsp_align-len>
      <Hsp_qseq>KVAVKMMKPGSMAPQAFLE-----EANLMKTLQHDKLVRLHAVVTDEP-IFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTARE-----GAKFPIKWTAPEAINYGS--FSIKSDVWSFGILLTEMVTFGRIPY-PGMTNPE</Hsp_qseq>
      <Hsp_hseq>QVAIKLIKRDSISNDYRKEVKIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQ--KKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFV-----NEFCSRNELMKTSCGSPC-YAAPELVISAEPYEARKADIWSCGVILYAILA-GYLPWDDDPNNPE</Hsp_hseq>
      <Hsp_midline>+VA+K++K  S++     E     E N +K L H  +V+L  V+ +   I IV EY   G    +++  +  RLK+     + +Q+  G+ +I  K  +HRDL+  N+L++ N    I DFG       NE+ +R          P  + APE +       + K+D+WS G++L  ++  G +P+     NPE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>7.96942e-11</Hsp_evalue>
      <Hsp_query-from>319</Hsp_query-from>
      <Hsp_query-to>945</Hsp_query-to>
      <Hsp_hit-from>147</Hsp_hit-from>
      <Hsp_hit-to>387</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>246</Hsp_align-len>
      <Hsp_qseq>RTLDKGGYF-------ITSRITFHTLQELVVYYHRVYNKKTKV-------AVKMMKPGSMAPQAFLEEANLMKTLQHDKLVRLHAVVTDEP--IFIVTEYMEKGSLLDFLKTSEG-SRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCK---IADFGLARIIEDNEYTAREGAKFPIKWTAPEA------INYGSFS-----------IKSDVWSFGILLTEMVTFGRIPYPG</Hsp_qseq>
      <Hsp_hseq>KLLDQMGFLREVDQWEITNRIVGNGTFGHVLITHNSKERDEDVCYHPENYAVKIIK---LKPNKFDKEARILLRLDHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKERMHTVVGTP-EYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLT-GISPFYG</Hsp_hseq>
      <Hsp_midline>+ LD+ G+        IT+RI  +     V+  H    +   V       AVK++K   + P  F +EA ++  L H  +++++    D    ++I  + +  G L  +L   +  + + + + + +  Q+ + + ++ D++ +HRDL+  NIL+     C    +ADFG+A+ +  N+         P ++ APE         Y SFS            K D+WS G++   M+T G  P+ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>9.52812e-11</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>226</Hsp_hit-from>
      <Hsp_hit-to>389</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>LEEANLMKTLQHDKLVRLHAVVTDEP-IFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCA-----QVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDN-------EYTAREGAKFPI---KWTAPEAINYGSFSIKSDVWSFGILLTEMVTFGRIPY</Hsp_qseq>
      <Hsp_hseq>IEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMK-------KYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIA-GKPPF</Hsp_hseq>
      <Hsp_midline>+E+  L K      +VRL +   DE  ++ + EY   G  L  +K       K   + + CA     Q+ + + ++     IHRD++  NIL++  +  K+ DFG A+++          EY     +K  +   ++ +PE +N      + D+W+FG +L +M+  G+ P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>1.18737e-10</Hsp_evalue>
      <Hsp_query-from>697</Hsp_query-from>
      <Hsp_query-to>1086</Hsp_query-to>
      <Hsp_hit-from>328</Hsp_hit-from>
      <Hsp_hit-to>460</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>137</Hsp_align-len>
      <Hsp_qseq>IHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEMVTFGRIPYPGMTN-PEVIRSL------ERGYRMPKPDNCPCELYSIMQECWRQKPEERPTFEYL</Hsp_qseq>
      <Hsp_hseq>IHRDIKPSNVLINSKGQIKLCDFGVSKKLINSIADTFVGTS---TYMSPERIQGNVYSIKGDVWSLGLMIIELVT-GEFPLGGHNDTPDGILDLLQRIVNEPSPRLPKDRIYSKEMTDFVNRCCIKNERERSSIHEL</Hsp_hseq>
      <Hsp_midline>IHRD++ +N+L+N     K+ DFG+++ + ++      G      + +PE I    +SIK DVWS G+++ E+VT G  P  G  + P+ I  L      E   R+PK      E+   +  C  +   ER +   L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>3.16924e-10</Hsp_evalue>
      <Hsp_query-from>478</Hsp_query-from>
      <Hsp_query-to>999</Hsp_query-to>
      <Hsp_hit-from>202</Hsp_hit-from>
      <Hsp_hit-to>382</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>184</Hsp_align-len>
      <Hsp_qseq>EANLMKTLQHDKLVRL-HAVVTDEPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTARE-----GAKFPI----KWTAPEAINYGSFSIKSDVWSFGILLTEMVTFGRIPYPGMTNPEVIRSLERGYRMPK</Hsp_qseq>
      <Hsp_hseq>ERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLK--EHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLV-GKPPYTGSNHKVIINKIQQNKQGPK</Hsp_hseq>
      <Hsp_midline>E +++  ++H  +V+L ++   +  ++++ +Y+  G L   LK  E   L +  +    A+++  + F+  K  ++RDL+  N L+N      + DFGL++   ++     E      A + I    ++ APE +   ++S   D +S G LL +M+  G+ PY G  +  +I  +++  + PK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>3.39307e-10</Hsp_evalue>
      <Hsp_query-from>421</Hsp_query-from>
      <Hsp_query-to>945</Hsp_query-to>
      <Hsp_hit-from>38</Hsp_hit-from>
      <Hsp_hit-to>228</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>192</Hsp_align-len>
      <Hsp_qseq>KVAVKMMKPGS--MAPQAFLEEANLMKTL-QHDKLV----RLHAVVTDE--PIFIVTEYMEKGSLLDFLKTSEG-SRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKF-----PIKW-TAPE-AINYGSFSIKSDVWSFGILLTEMVTFGRIPYPG</Hsp_qseq>
      <Hsp_hseq>KVAIKKIQPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVS-GKPLFPG</Hsp_hseq>
      <Hsp_midline>KVA+K ++P S  +     + E  L++   +H+ ++    ++  V  D+   +++V E ME          + G S L    +     Q+   +  I     IHRD++ +N+L+N N   K+ DFGLAR +  +  +      F       +W  APE  + +  ++   D+WS G +L EMV+ G+  +PG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YIL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:183937:186369:1 gene:YIL095W transcript:YIL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRK1 description:Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton and reduces endocytic ability of cell through the phosphorylation of the Pan1p-Sla1p-End3p protein complex; PRK1 has a paralog, ARK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001357]</Hit_def>
  <Hit_accession>YIL095W</Hit_accession>
  <Hit_len>810</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>3.70943e-10</Hsp_evalue>
      <Hsp_query-from>550</Hsp_query-from>
      <Hsp_query-to>906</Hsp_query-to>
      <Hsp_hit-from>104</Hsp_hit-from>
      <Hsp_hit-to>235</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>132</Hsp_align-len>
      <Hsp_qseq>IFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIE--DKNYIHRDLRAANILVNVNLVCKIADFGLA-------RIIEDNEYTARE-GAKFPIKWTAPEAIN-YGSFSI--KSDVWSFGILL</Hsp_qseq>
      <Hsp_hseq>VFVLMEFCERGGLIDFMNTRLQNRLQESEILEIMSQTVQGITAMHALQPPLIHRDIKIENVLISHDGLYKVCDFGSVSGVIRPPRNTQEFNYVQHDILTNTTAQYRSPEMIDLYRGLPIDEKSDIWALGVFL</Hsp_hseq>
      <Hsp_midline>+F++ E+ E+G L+DF+ T   +RL++ +++++ +Q  +G+  +       IHRD++  N+L++ + + K+ DFG         R  ++  Y   +       ++ +PE I+ Y    I  KSD+W+ G+ L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>4.81483e-10</Hsp_evalue>
      <Hsp_query-from>541</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>92</Hsp_hit-from>
      <Hsp_hit-to>220</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>140</Hsp_align-len>
      <Hsp_qseq>DEPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMID------MCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINYGS-FSIKSDVWSFGILLTEMVTFGRIPY</Hsp_qseq>
      <Hsp_hseq>DTSLWIIMEHCAGGSLRSLLR---------PGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPY-WMAPEVIMEGVYYDTKVDIWSLGITTYEIAT-GNPPY</Hsp_hseq>
      <Hsp_midline>D  ++I+ E+   GSL   L+         P  ID      +  ++   +  I   N IHRD++AAN+L+      K+ DFG+A  +       +  A  P  W APE I  G  +  K D+WS GI   E+ T G  PY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>5.34556e-10</Hsp_evalue>
      <Hsp_query-from>478</Hsp_query-from>
      <Hsp_query-to>915</Hsp_query-to>
      <Hsp_hit-from>107</Hsp_hit-from>
      <Hsp_hit-to>276</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>174</Hsp_align-len>
      <Hsp_qseq>EANLMKTLQHDKLVRLHAVVTDEPIFIVTE---------YMEKGSLLDFLKTSEGSRLKQPKM-IDMC------AQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARII----EDNEYT--AREGAKFP----IKW-TAPE-AINYGSFSIKSDVWSFGILLTEM</Hsp_qseq>
      <Hsp_hseq>EITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYM----ILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEF</Hsp_hseq>
      <Hsp_midline>E  ++K L H  +++L  +V D    I            YM    +L ++       L  P++ ++MC       Q+ EG+ +I    ++HRD++ ANIL++ N V K+ADFGLAR+      + +Y   A  GAK+      +W  APE  +    ++   D+W  G +  E </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>1.80788e-09</Hsp_evalue>
      <Hsp_query-from>655</Hsp_query-from>
      <Hsp_query-to>918</Hsp_query-to>
      <Hsp_hit-from>136</Hsp_hit-from>
      <Hsp_hit-to>227</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>95</Hsp_align-len>
      <Hsp_qseq>QVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKF-----PIKW-TAPE-AINYGSFSIKSDVWSFGILLTEMV</Hsp_qseq>
      <Hsp_hseq>QILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPV---ENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFL</Hsp_hseq>
      <Hsp_midline>Q+  G+ +I   + +HRDL+  N+LVN +   KI DFGLAR   +N     E ++F       +W  APE  ++Y  ++   DVWS G +L E +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.5362</Hsp_bit-score>
      <Hsp_score>140</Hsp_score>
      <Hsp_evalue>1.95608e-09</Hsp_evalue>
      <Hsp_query-from>472</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>172</Hsp_hit-from>
      <Hsp_hit-to>337</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>174</Hsp_align-len>
      <Hsp_qseq>LEEANLMKTLQHDKLVRLHAVVTDE-PIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCA-----QVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKF------------PIKWTAPEAINYGSFSIKSDVWSFGILLTEMVTFGRIPY</Hsp_qseq>
      <Hsp_hseq>VEKLALQKLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIK-------KYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLA-GKPPF</Hsp_hseq>
      <Hsp_midline>+E+  L K      + +L     DE  ++ + EY   G  L  +K       K   + + CA     Q+ + +  + +   IHRD++  NIL++ N+  K+ DFG A+I+ +      +G  +              ++ +PE +N      + D+W+FG +L +M+  G+ P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>2.93202e-09</Hsp_evalue>
      <Hsp_query-from>553</Hsp_query-from>
      <Hsp_query-to>945</Hsp_query-to>
      <Hsp_hit-from>524</Hsp_hit-from>
      <Hsp_hit-to>656</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>137</Hsp_align-len>
      <Hsp_qseq>FIVTEYMEKGSLLDFLKT---SEGSRLKQPKMIDMCAQVAEGMAFIEDKNYI-HRDLRAANILVNVNLVCKIADFGLAR--IIEDNEYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEMVTFGRIPYPG</Hsp_qseq>
      <Hsp_hseq>YIMTELCENGNLDGFLQEQVIAKKKRLEDWRIWKIIVELSLALRFIHDSCHIVHLDLKPANVMITFEGNLKLGDFGMATHLPLEDKSF-ENEGDR---EYIAPEIISDCTYDYKADIFSLGLMIVEIAANVVLPDNG</Hsp_hseq>
      <Hsp_midline>+I+TE  E G+L  FL+    ++  RL+  ++  +  +++  + FI D  +I H DL+ AN+++      K+ DFG+A    +ED  +   EG +   ++ APE I+  ++  K+D++S G+++ E+     +P  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>3.06997e-09</Hsp_evalue>
      <Hsp_query-from>463</Hsp_query-from>
      <Hsp_query-to>918</Hsp_query-to>
      <Hsp_hit-from>202</Hsp_hit-from>
      <Hsp_hit-to>359</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>158</Hsp_align-len>
      <Hsp_qseq>QAFLEEANLMKTLQHDKLVRLHAVVTDEP-IFIVTEYMEKGSL-LDFLKTSEGSRLKQPKMI-DMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAK--FPIKWTAPE-AINYGSFSIKSDVWSFGILLTEMV</Hsp_qseq>
      <Hsp_hseq>QSACREMALCRELHNKHLTTLVEIFLERKCVHMVYEYAEHDLLQIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDGCVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELI</Hsp_hseq>
      <Hsp_midline>Q+   E  L + L +  L  L  +  +   + +V EY E   L +    +    R+  P+M+  +  Q+ +G++++     +HRDL+ ANI+V ++   KI D GLAR   +   T   G K    I + APE  +    ++   D+WS G +  E++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>4.18147e-09</Hsp_evalue>
      <Hsp_query-from>475</Hsp_query-from>
      <Hsp_query-to>975</Hsp_query-to>
      <Hsp_hit-from>103</Hsp_hit-from>
      <Hsp_hit-to>288</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>187</Hsp_align-len>
      <Hsp_qseq>EEANLMKTLQHDKLVRLHAVVTD---EPIFIVTEYMEKGSLL------DFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLA--------RIIEDNEYTAREGAKFPIKWTAPEAINYG---SFSIKSDVWSFGILLTEMVTFGRIPYPGMTNPEVIRSL</Hsp_qseq>
      <Hsp_hseq>QEIEVMKRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLL-FGKLPFNANSGLELFDSI</Hsp_hseq>
      <Hsp_midline>+E  +MK   H+ +V L+ ++ D     +++V EY  +G +         +K    S L   +   +   V  G+ ++  +   HRD++ +N+L++ N   KI+DFG+A         I   +E   +  A     + APE  +     S S   D+WS G+ +  ++ FG++P+   +  E+  S+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>7.12103e-09</Hsp_evalue>
      <Hsp_query-from>460</Hsp_query-from>
      <Hsp_query-to>975</Hsp_query-to>
      <Hsp_hit-from>224</Hsp_hit-from>
      <Hsp_hit-to>393</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>177</Hsp_align-len>
      <Hsp_qseq>PQAFLEEANLMKTLQHDKLVRLHAVV--TDEPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDN-EYTAREGAKFPIKWTAPEAINYGS--FSIKSDVWSFGILLTEMVTFGRIPYPGMTNPEVIRSL</Hsp_qseq>
      <Hsp_hseq>PITSIREIKLLQSFDHPNVSTIKEIMVESQKTVYMIFEYADND--LSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKMNSRADYTNR----VITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAI-FQGSNELEQIESI</Hsp_hseq>
      <Hsp_midline>P   + E  L+++  H  +  +  ++  + + ++++ EY +    L  L  ++  ++   +   +  Q+  GM ++ D   +HRD++ +NIL++     KI DFGLAR +    +YT R        W  P  +  G+  +  + D+W  G LL E+     I + G    E I S+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>8.52866e-09</Hsp_evalue>
      <Hsp_query-from>337</Hsp_query-from>
      <Hsp_query-to>1080</Hsp_query-to>
      <Hsp_hit-from>850</Hsp_hit-from>
      <Hsp_hit-to>1091</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>114</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>254</Hsp_align-len>
      <Hsp_qseq>GYFITSRITFHTLQELVVYYHRVYNKKTKVA--VKMMKPGSMAPQAFLEEANLMKTLQHDKLVRLHAVVTDEPIFIVTE-YMEKGS--LLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINYGSFSIK-SDVWSFGILLTEMVTFGRIPYPGMTNPEVIRSLERGYRMPKPDNCPCELYSIMQECWRQKPEERPTFE</Hsp_qseq>
      <Hsp_hseq>GAYGKVNLCIHNREHYIVVIKMIFKERILVDTWVRDRKLGTI-PSEIQIMATLNKNSQENILKLLDFFEDDDYYYIETPVHGETGSIDLFDVIEFKKDMVEHEAKLV--FKQVVASIKHLHDQGIVHRDIKDENVIVDSHGFVKLIDFGSAAYIKSGPFDVFVGT---MDYAAPEVLGGSSYKGKPQDIWALGVLLYTII-YKENPYYNID-----EILEGELRFDKSEHVSEECISLIKRILTREVDKRPTID</Hsp_hseq>
      <Hsp_midline>G +    +  H  +  +V    ++ ++  V   V+  K G++ P      A L K  Q + L  L     D+  +I T  + E GS  L D ++  +     + K++    QV   +  + D+  +HRD++  N++V+ +   K+ DFG A  I+   +    G    + + APE +   S+  K  D+W+ G+LL  ++ +   PY  +        LE   R  K ++   E  S+++    ++ ++RPT +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>1.39101e-08</Hsp_evalue>
      <Hsp_query-from>523</Hsp_query-from>
      <Hsp_query-to>981</Hsp_query-to>
      <Hsp_hit-from>775</Hsp_hit-from>
      <Hsp_hit-to>934</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>171</Hsp_align-len>
      <Hsp_qseq>LHAVVTDEPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARII-----------------EDNEYTAREGAKFPIKWTAPEAIN-YGSFSIKSDVWSFGILLTEMVTFGRIPYPGMTNPEVIRSLER</Hsp_qseq>
      <Hsp_hseq>MTAVKKKSTLFIQMEYCENRTLYDLIH-SENLNQQRDEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNVKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMY----VATEVLDGTGHYNEKIDMYSLGIIFFEMI------YPFSTGMERVNILKK</Hsp_hseq>
      <Hsp_midline>+ AV     +FI  EY E  +L D +  SE    ++ +   +  Q+ E +++I  +  IHRDL+  NI ++ +   KI DFGLA+ +                  DN  +A   A +     A E ++  G ++ K D++S GI+  EM+      YP  T  E +  L++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>2.08061e-08</Hsp_evalue>
      <Hsp_query-from>427</Hsp_query-from>
      <Hsp_query-to>1068</Hsp_query-to>
      <Hsp_hit-from>851</Hsp_hit-from>
      <Hsp_hit-to>1066</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>AVKMMKPGSMAPQAFLEEANLMKTL-------QHDKLVRLH-AVVTDEPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKF--PIKWTAPEAINYGSFSIKSDVWSFGILLTEMVTFGRIPYPGMTNPEVIRSLERGYRMPKPDNCPCELYSIMQECWRQKPEER</Hsp_qseq>
      <Hsp_hseq>AIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHV---QNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCK---DEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQML-LCQSPFSGDDEDEVFNAILTDEPL-YPIDMAGEIVQIFQGLLTKDPEKR</Hsp_hseq>
      <Hsp_midline>A+K++K  ++     +E A   K +       +H  L  L+ +  T+  I+   E++  G L+  +   +  RL   +     A+V   + +  D   I+RDL+  NIL+      KIAD+GL +   D  +     + F    ++ APE +    ++   D W+FG+LL +M+   + P+ G    EV  ++     +  P +   E+  I Q    + PE+R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>2.39023e-08</Hsp_evalue>
      <Hsp_query-from>385</Hsp_query-from>
      <Hsp_query-to>1035</Hsp_query-to>
      <Hsp_hit-from>20</Hsp_hit-from>
      <Hsp_hit-to>236</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>231</Hsp_align-len>
      <Hsp_qseq>VVYYHRVYNKKTKVAVKMMKPGSMAP---QAFLEEANLMKTLQHDKLVRLHAVVTDEPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGM------AFIEDKNYI-HRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKFPIKW-TAPEAINYGS--FSIKSDVWSFGILLTEMVTFGRIPY-PGMTNPEVIRSLERGYRMPKPDNCPCELYSIM</Hsp_qseq>
      <Hsp_hseq>VVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNVIEL--------IDIFMAYDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNVV--TRWYRAPELL-FGAKHYTSAIDIWSVGVIFAELML--RIPYLPGQNDVDQMEVTFRALGTPTDRDWP-EVSSFM</Hsp_hseq>
      <Hsp_midline>VVY    ++   K+A+K +K          + + E   ++ +QH  ++ L        I I   Y     +L+FL T     +K   ++   A +   M       +   +N+I HRDL+  N+L + +   K+ADFGLAR I               +W  APE + +G+  ++   D+WS G++  E++   RIPY PG  + + +    R    P   + P E+ S M</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>3.07718e-08</Hsp_evalue>
      <Hsp_query-from>493</Hsp_query-from>
      <Hsp_query-to>981</Hsp_query-to>
      <Hsp_hit-from>71</Hsp_hit-from>
      <Hsp_hit-to>238</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>171</Hsp_align-len>
      <Hsp_qseq>KTLQHDKLVRL-HAVVTDEPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIE-DKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREG--AKFPIKWTAPEAI--NYGSFSIKSDVWSFGILLTEMVTFGRIPY--PGMTNPEVIRSLER</Hsp_qseq>
      <Hsp_hseq>KCSKHPNVLRLIDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQF--YFQQLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLT-GQTPWELPSLENEDFVFFIEN</Hsp_hseq>
      <Hsp_midline>K  +H  ++RL    V+ E ++I+ E  + G L D ++   G      +      Q+   + ++  +    HRD++  NIL++ N   K+ADFGLA      + T R     +    + APE +    G ++ ++D+WS GILL  ++T G+ P+  P + N + +  +E </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>3.78198e-08</Hsp_evalue>
      <Hsp_query-from>409</Hsp_query-from>
      <Hsp_query-to>936</Hsp_query-to>
      <Hsp_hit-from>46</Hsp_hit-from>
      <Hsp_hit-to>231</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>197</Hsp_align-len>
      <Hsp_qseq>NKKTKVAVKMMKPGSMAPQAFLEEANLMKTLQHDKLVRL---HAVV-----TD---------EPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAR---EGAKFPIKWTAPE-AINYGSFSIKSDVWSFGILLTEMVTFGRIP</Hsp_qseq>
      <Hsp_hseq>NEETHVAIRKI------PNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLYEELME-CDLSQIIRSEQ--RLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELL--GRKP</Hsp_hseq>
      <Hsp_midline>N++T VA++ +      P AF  + +  +TL+  KL+R    H  +     TD           +++  E ME   L   +++ +  RL+         Q+   + +I   N +H DL+  N+LVN +   KI +FGL+    +N        +G    I + APE  +NY   +   D+WS G +L E++  GR P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>5.71553e-08</Hsp_evalue>
      <Hsp_query-from>313</Hsp_query-from>
      <Hsp_query-to>774</Hsp_query-to>
      <Hsp_hit-from>4</Hsp_hit-from>
      <Hsp_hit-to>155</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>165</Hsp_align-len>
      <Hsp_qseq>KIRTLDKGGYFITSRITFHTLQELVVYYHRVYNKKTKVAVKMMKPGSMAPQAFLEEANLMKTLQ----HDKLVRLHAVVTDEPIFI-VTEYMEKGSLLDFL--KTSEGS----RLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLA</Hsp_qseq>
      <Hsp_hseq>KLRSIQSG--------TFSTVYKAWSTTHNRY-----VALKITPKYKTSEANMKNEYDVMKILSSCNPHPNICSMLDFYTDDSYYIMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQIDMQKIIKQLCSAISFAHSLGIAHRDIKPENILLTINGDIKLADWGHA</Hsp_hseq>
      <Hsp_midline>K+R++  G        TF T+ +     H  Y     VA+K+      +      E ++MK L     H  +  +    TD+  +I V EY E G L DFL    S+GS     L Q  M  +  Q+   ++F       HRD++  NIL+ +N   K+AD+G A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>7.17165e-08</Hsp_evalue>
      <Hsp_query-from>484</Hsp_query-from>
      <Hsp_query-to>945</Hsp_query-to>
      <Hsp_hit-from>65</Hsp_hit-from>
      <Hsp_hit-to>232</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>178</Hsp_align-len>
      <Hsp_qseq>NLMKTLQHDKLVRLHAVVTDEP-IFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDM-----CAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKF------------------PIKWTAPEAINYGSFSIKSDVWSFGILLTEMVTFGRIPYPG</Hsp_qseq>
      <Hsp_hseq>NLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLH-------KMGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPS--LSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQ-GQPPFRG</Hsp_hseq>
      <Hsp_midline>NL+    H  +++L+    DE  ++ V ++   G LL  L        K     D+      AQ+ + + FI     IHRDL+  N+L++ +    I DFG A  I+ +   + + AKF                    ++ +PE + Y      SD+W+ G ++ + V  G+ P+ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>8.14907e-08</Hsp_evalue>
      <Hsp_query-from>550</Hsp_query-from>
      <Hsp_query-to>999</Hsp_query-to>
      <Hsp_hit-from>488</Hsp_hit-from>
      <Hsp_hit-to>653</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>171</Hsp_align-len>
      <Hsp_qseq>IFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPE-AINYGSFSIKSDVWSFGILLTEM------------------VTFGRIPYPGMTNPEVIRSLERGY--RMPK</Hsp_qseq>
      <Hsp_hseq>LYLVTDYMSGGELFWHLQ-KEG-RFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGT---TEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNRNPK</Hsp_hseq>
      <Hsp_midline>+++VT+YM  G L   L+  EG R  + +     A++   +  + D + ++RDL+  NIL++ N    + DFGL++    +      G     ++ APE  ++   ++   D WS G+L+ EM                  + FG++ +P     +  RS  +G   R PK</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>8.44617e-08</Hsp_evalue>
      <Hsp_query-from>655</Hsp_query-from>
      <Hsp_query-to>936</Hsp_query-to>
      <Hsp_hit-from>149</Hsp_hit-from>
      <Hsp_hit-to>248</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>102</Hsp_align-len>
      <Hsp_qseq>QVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKFPI------KW-TAPE-AINYGSFSIKSDVWSFGILLTEMVTFGRIP</Hsp_qseq>
      <Hsp_hseq>QILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEF--YARKP</Hsp_hseq>
      <Hsp_midline>Q+  G+ +I   + IHRDL+  NIL  +N   KI DFGLAR I    +      +  I      +W  APE  ++   +S   D+W+ G +L E   + R P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>1.01228e-07</Hsp_evalue>
      <Hsp_query-from>433</Hsp_query-from>
      <Hsp_query-to>903</Hsp_query-to>
      <Hsp_hit-from>71</Hsp_hit-from>
      <Hsp_hit-to>228</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>163</Hsp_align-len>
      <Hsp_qseq>KMMKPGSMAPQAFLEEANLMKTLQHDKLVRLHA-VVTDEPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILV-----NVNLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGIL</Hsp_qseq>
      <Hsp_hseq>KALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFD--RILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLV--VADFGIAKRLKSDEELLYKPAG-SLGYVAPEVLTQDGHGKPCDIWSIGVI</Hsp_hseq>
      <Hsp_midline>K +K   +  +A  +E ++++ L H  +V       + +  +I+T+  + G L D  +  +  +  +   + +  ++   + ++  +N +HRDL+  N+L         LV  +ADFG+A+ ++ +E    + A   + + APE +         D+WS G++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>1.05821e-07</Hsp_evalue>
      <Hsp_query-from>313</Hsp_query-from>
      <Hsp_query-to>975</Hsp_query-to>
      <Hsp_hit-from>326</Hsp_hit-from>
      <Hsp_hit-to>554</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>249</Hsp_align-len>
      <Hsp_qseq>KIRTLDKGG----YFITSRITFHTLQELVVYYHRVYNKKTKVAVKMMKPGSMAPQAFLEEANLMKTLQHDKLVRL-HAVVTDEPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLA-------------------RIIED----NEYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEMVTFGRIPYPGMTNPEVIRSL</Hsp_qseq>
      <Hsp_hseq>KIRLLGQGDVGKVYLVRERDTNQ------IFALKVLNKHEMIKRKKIK-------RVLTEQEILATSDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTE------EYLAPEVIRGNGHTAAVDWWTLGILIYEML-FGCTPFKGDNSNETFSNI</Hsp_hseq>
      <Hsp_midline>KIR L +G     Y +  R T        ++  +V NK   +  K +K         L E  ++ T  H  +V L H+  T + +++  EY   G     L+T +   + +       ++V   + ++    +I+RDL+  NIL++ +    ++DF L+                   +I  D    N +   E      ++ APE I     +   D W+ GIL+ EM+ FG  P+ G  + E   ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>1.61484e-07</Hsp_evalue>
      <Hsp_query-from>478</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>1149</Hsp_hit-from>
      <Hsp_hit-to>1304</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>162</Hsp_align-len>
      <Hsp_qseq>EANLMKTLQ---HDKLVRLHAVVTDEPIFIVTE--YMEKG--SLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINYGSFSIK-SDVWSFGILLTEMVTFGRIPY</Hsp_qseq>
      <Hsp_hseq>EIQIMATLNKKPHENILRLLDFFEDDDYYYIETPVHGETGCIDLFDLIEFKTNMTEFEAKLI--FKQVVAGIKHLHDQGIVHRDIKDENVIVDSKGFVKIIDFGSAAYVKSGPFDVFVGT---IDYAAPEVLGGNPYEGQPQDIWAIGILLYTVV-FKENPF</Hsp_hseq>
      <Hsp_midline>E  +M TL    H+ ++RL     D+  + +    + E G   L D ++        + K+I    QV  G+  + D+  +HRD++  N++V+     KI DFG A  ++   +    G    I + APE +    +  +  D+W+ GILL  +V F   P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>2.52981e-07</Hsp_evalue>
      <Hsp_query-from>532</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>101</Hsp_hit-from>
      <Hsp_hit-to>232</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>139</Hsp_align-len>
      <Hsp_qseq>VVTDEPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAI---NYGSFSIKSDVWSFGILLTEMVTFGRIPY</Hsp_qseq>
      <Hsp_hseq>IVTESKVWMALEYCPGKELYDHLLSLRRISLLE--CGELFAQISGAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTR--ECMTKTTLETVCGTTVYMAPELIERRTYDGFKI--DIWSLGVILYTLIT-GYLPF</Hsp_hseq>
      <Hsp_midline>+VT+  +++  EY     L D L +     L +    ++ AQ++  + +    + +HRDL+  NIL++ N   K+ DFG  R  E    T  E       + APE I    Y  F I  D+WS G++L  ++T G +P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>2.7948e-07</Hsp_evalue>
      <Hsp_query-from>463</Hsp_query-from>
      <Hsp_query-to>939</Hsp_query-to>
      <Hsp_hit-from>254</Hsp_hit-from>
      <Hsp_hit-to>445</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>199</Hsp_align-len>
      <Hsp_qseq>QAFLEEANLMKTLQHDKLVRLHAVVTDEPIFIVTE----------------------YMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILV-----NVN------LVCK-----IADFGLARIIEDNEY-TAREGAKFPIKWTAPEAINYGSFSIK-SDVWSFGILLTEMVTFGRIPY</Hsp_qseq>
      <Hsp_hseq>NSLTRELQVLKSLNHPCIVKLLGI--NNPIFVTSKKPLCDLIIKTPRALPPCDMIMSYCPAGDLLAAVMARNG-RLEAWLIQRIFTEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLCKKIENNEMCTARCGSE---DYVSPEILMGVPYDGHLSDTWALGVILYSLFE-DRLPF</Hsp_hseq>
      <Hsp_midline> +   E  ++K+L H  +V+L  +  + PIF+ ++                      Y   G LL  +    G RL+   +  +  +V   + ++ + + IHRDL+  NIL+     ++N      + CK     +ADFGL + IE+NE  TAR G++    + +PE +    +    SD W+ G++L  +    R+P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>4.36128e-07</Hsp_evalue>
      <Hsp_query-from>655</Hsp_query-from>
      <Hsp_query-to>918</Hsp_query-to>
      <Hsp_hit-from>147</Hsp_hit-from>
      <Hsp_hit-to>234</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>91</Hsp_align-len>
      <Hsp_qseq>QVAEGMAFIEDKNYIHRDLRAANILVNVNL-VCKIADFGLARIIEDNEYT-AREGAKFPIKWTAPEA-INYGSFSIKSDVWSFGILLTEMV</Hsp_qseq>
      <Hsp_hseq>QIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSISYICSRF---YRAPELIIGCTQYTTQIDIWGLGCVMGEML</Hsp_hseq>
      <Hsp_midline>Q+A GM ++      HRD++ +N+LV+    V KI DFG A+ +E N+ + +   ++F   + APE  I    ++ + D+W  G ++ EM+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YJR059W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:545787:548243:1 gene:YJR059W transcript:YJR059W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK2 description:Serine/threonine protein kinase; involved in regulation of ion transport across plasma membrane; carboxyl terminus is essential for glucose-dependent Pma1p activation via phosphorylation of Pma1p-Ser899; enhances spermine uptake; PTK2 has a paralog, PTK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003820]</Hit_def>
  <Hit_accession>YJR059W</Hit_accession>
  <Hit_len>818</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>6.64853e-07</Hsp_evalue>
      <Hsp_query-from>655</Hsp_query-from>
      <Hsp_query-to>918</Hsp_query-to>
      <Hsp_hit-from>371</Hsp_hit-from>
      <Hsp_hit-to>476</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>106</Hsp_align-len>
      <Hsp_qseq>QVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLAR------------------IIEDNEYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEMV</Hsp_qseq>
      <Hsp_hseq>QVAQGIKFCHDNGIAHRDLKPENVLISKEGICKLTDFGISDWYHVIPHDYTSPVKTCQGMIGSPPYTPPEVMYFDAKKHYPEKFQKPYNPLAMDSYALGIMLITMI</Hsp_hseq>
      <Hsp_midline>QVA+G+ F  D    HRDL+  N+L++   +CK+ DFG++                   +I    YT  E   F  K   PE        +  D ++ GI+L  M+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YIL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:287790:288908:-1 gene:YIL035C transcript:YIL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA1 description:Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000001297]</Hit_def>
  <Hit_accession>YIL035C</Hit_accession>
  <Hit_len>372</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>7.0117e-07</Hsp_evalue>
      <Hsp_query-from>505</Hsp_query-from>
      <Hsp_query-to>960</Hsp_query-to>
      <Hsp_hit-from>130</Hsp_hit-from>
      <Hsp_hit-to>279</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>165</Hsp_align-len>
      <Hsp_qseq>HDKLVRLHAVVTDEPI----FIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDM-----CAQVAEGMAFIEDKNYIHRDLRAANILVN-VNLVCKIADFGLARIIEDN-EYTAREGAKFPIKWTAPEA-INYGSFSIKSDVWSFGILLTEMVTFGRIP-YPGMTNPE</Hsp_qseq>
      <Hsp_hseq>HANIIHLFDIIKD-PISKTPALVFEYVDN---VDF-------RILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRF---FKGPELLVDYRMYDYSLDLWSFGTMLASMI-FKREPFFHGTSNTD</Hsp_hseq>
      <Hsp_midline>H  ++ L  ++ D PI     +V EY++    +DF       R+  PK+ D+       ++ + + +      +HRD++  N++++  N   ++ D+GLA     N EY  R  ++F   +  PE  ++Y  +    D+WSFG +L  M+ F R P + G +N +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>1.42371e-06</Hsp_evalue>
      <Hsp_query-from>397</Hsp_query-from>
      <Hsp_query-to>975</Hsp_query-to>
      <Hsp_hit-from>519</Hsp_hit-from>
      <Hsp_hit-to>729</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>214</Hsp_align-len>
      <Hsp_qseq>HRVYNKKTKVAVKMMKPGSMAPQAFLEEANLMKTLQHDKLVRL-HAVVTDEPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKFPI--------------------KWTAPEAINYGSFSIKSDVWSFGILLTEMVTFGRIPYPGMTNPEVIRSL</Hsp_qseq>
      <Hsp_hseq>NRVYALKVLSKDEMIKRNKI--KRVLTEQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEML-FGFTPFKGDNTNETFTNI</Hsp_hseq>
      <Hsp_midline>+RVY  K     +M+K   +  +  L E  ++ T  H  +V L H+  +++ +++  EY   G     L+T +   + +       ++V   + ++    +I+RDL+  NIL++ +    ++DF L+   +D++    +G+                        ++ APE I     +   D W+ GIL+ EM+ FG  P+ G    E   ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1184700706</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056646-RA transcript Note:&quot;Similar to TTPAL Alpha-tocopherol transfer protein-like (Homo sapiens)&quot; offset:0 AED:0.44 eAED:0.51 QI:0|0.33|0.5|1|1|1|4|0|265</Iteration_query-def>
  <Iteration_query-len>798</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>88</Statistics_hsp-len>
      <Statistics_eff-space>415321526</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056647-RA transcript Note:&quot;Similar to TTPAL Alpha-tocopherol transfer protein-like (Homo sapiens)&quot; offset:173 AED:0.28 eAED:0.28 QI:173|1|1|1|0|0|6|1366|315</Iteration_query-def>
  <Iteration_query-len>2487</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YMR079W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:424989:426059:1 gene:YMR079W transcript:YMR079W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SEC14 description:Phosphatidylinositol/phosphatidylcholine transfer protein; involved in regulating PtdIns, PtdCho, and ceramide metabolism, products of which regulate intracellular transport and UPR; has a role in localization of lipid raft proteins; functionally homologous to mammalian PITPs; SEC14 has a paralog, YKL091C, that arose from the whole genome duplication [Source:SGD;Acc:S000004684]</Hit_def>
  <Hit_accession>YMR079W</Hit_accession>
  <Hit_len>304</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>1.70224e-11</Hsp_evalue>
      <Hsp_query-from>315</Hsp_query-from>
      <Hsp_query-to>926</Hsp_query-to>
      <Hsp_hit-from>52</Hsp_hit-from>
      <Hsp_hit-to>268</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>220</Hsp_align-len>
      <Hsp_qseq>RTDDAFLLRFLRARKFD---HEKTFKLVESYYKCHETWPDIFQNFRPSAVKALLGSGFIRVLPERDSKGRRVIIQSPGKWN-------PSTTPMMDNIRAMYMT-----MELLIQSEETQVNGITILADHKGVRLAHVTNFTPSLMKKITTVMQDAFPIRIKGHNTVNEPSIFKAMFALMKPFLKEKMRKRMIFHGTDFL-SLHKQISPDILPAEYGGTA</Hsp_qseq>
      <Hsp_hseq>RLDDSTLLRFLRARKFDVQLAKEMFENCEKWRKDYGT-DTILQDFHYDE-KPLIAKFYPQYYHKTDKDGRPVYFEELGAVNLHEMNKVTSEERMLKNLVWEYESVVQYRLPACSRAAGHLVETSCTIMDLKGISISSAYSVM-SYVREASYISQNYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFILGSSYQKELLKQIPAENLPVKFGGKS</Hsp_hseq>
      <Hsp_midline>R DD+ LLRFLRARKFD    ++ F+  E + K + T   I Q+F     K L+   + +   + D  GR V  +  G  N        S   M+ N+   Y +     +    ++    V     + D KG+ ++   +   S +++ + + Q+ +P R+     +N P  F   F L KPFL      ++   G+ +   L KQI  + LP ++GG +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YKL091C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:269718:270650:-1 gene:YKL091C transcript:YKL091C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YKL091C description:Putative phosphatidylinositol/phosphatidylcholine transfer protein; possibly involved in lipid metabolism; localizes to the nucleus; contains a CRAL/TRIO domain and binds several lipids in a large-scale study; YKL091C has a paralog, SEC14, that arose from the whole genome duplication [Source:SGD;Acc:S000001574]</Hit_def>
  <Hit_accession>YKL091C</Hit_accession>
  <Hit_len>310</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.5362</Hsp_bit-score>
      <Hsp_score>140</Hsp_score>
      <Hsp_evalue>1.14972e-09</Hsp_evalue>
      <Hsp_query-from>315</Hsp_query-from>
      <Hsp_query-to>926</Hsp_query-to>
      <Hsp_hit-from>48</Hsp_hit-from>
      <Hsp_hit-to>270</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>RTDDAFLLRFLRARKFDHEKTFKLVESYYKCHETWP-----DIFQNFRPSAVKAL--LGSGFIRVLPERDSKGRRVIIQSPGKWN-------PSTTPMMDNIRAMYMTMELLIQSEETQVNGITI-----LADHKGVRLAHVTNFTPSLMKKITTVMQDAFPIRIKGHNTVNEPSIFKAMFALMKPFLKEKMRKRMIFHGTDFL-SLHKQISPDILPAEYGGTA</Hsp_qseq>
      <Hsp_hseq>RLDDSTLLRFLRARKFDINASVEMFVETERWREEYGANTIIEDYENNKEAEDKERIKLAKMYPQYYHHVDKDGRPLYFEELGGINLKKMYKITTEKQMLRNLVKEYELFATYRVPACSRRAGYLIETSCTVLDLKGISLSNAYHVL-SYIKDVADISQNYYPERMGKFYIIHSPFGFSTMFKMVKPFLDPVTVSKIFILGSSYKKELLKQIPIENLPVKYGGTS</Hsp_hseq>
      <Hsp_midline>R DD+ LLRFLRARKFD   + ++     +  E +      + ++N + +  K    L   + +     D  GR +  +  G  N        +   M+ N+   Y           ++  G  I     + D KG+ L++  +   S +K +  + Q+ +P R+     ++ P  F  MF ++KPFL      ++   G+ +   L KQI  + LP +YGGT+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1657372177</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056648-RA transcript Note:&quot;Similar to PKIA cAMP-dependent protein kinase inhibitor alpha (Gallus gallus)&quot; offset:35 AED:0.02 eAED:0.02 QI:35|1|1|1|1|1|2|1762|69</Iteration_query-def>
  <Iteration_query-len>2007</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1306707591</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056649-RA transcript Note:&quot;Similar to TRIB2 Tribbles homolog 2 (Pongo abelii)&quot; offset:0 AED:0.12 eAED:0.13 QI:0|0.5|0.33|1|1|1|3|192|394</Iteration_query-def>
  <Iteration_query-len>1377</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>122.094</Hsp_bit-score>
      <Hsp_score>305</Hsp_score>
      <Hsp_evalue>2.81397e-30</Hsp_evalue>
      <Hsp_query-from>256</Hsp_query-from>
      <Hsp_query-to>1071</Hsp_query-to>
      <Hsp_hit-from>52</Hsp_hit-from>
      <Hsp_hit-to>310</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>138</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>275</Hsp_align-len>
      <Hsp_qseq>IGHYVLLEPL-EGQ--RMLRAVNTHTGRELVCKVRRSRRVCLGAVWVAVYARCVASYRDSLAAYFRIPPHESVACVDEVLLGEHWAYAFLERGCGDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALPEALSPKARCLIRDLLRRDPSERLSARDILHHPWFACDF</Hsp_qseq>
      <Hsp_hseq>IGNYQIVKTLGEGSFGKVKLAYHTTTGQKVALKII-NKKVLAKSDMQGRIEREIS--------YLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIM---TDGNFLKTSCGSPNYAAPEVISGKLYAGPEV----DVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGAAGLIKRMLIVNPLNRISIHEIMQDDWFKVDL</Hsp_hseq>
      <Hsp_midline>IG+Y +++ L EG   ++  A +T TG+++  K+  +++V   +       R ++        Y R+  H  +  + +V+  +      +E    +L  ++    ++ E+EA R F Q +SAV++CH+H IV RDLK    +  +   +++   GL ++    +D + L    G P Y +PE+++    +G       DVWS GV+LY ML  + PF +     LF  I  G Y LP+ LSP A  LI+ +L  +P  R+S  +I+   WF  D </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>105.531</Hsp_bit-score>
      <Hsp_score>262</Hsp_score>
      <Hsp_evalue>1.3257e-24</Hsp_evalue>
      <Hsp_query-from>442</Hsp_query-from>
      <Hsp_query-to>1053</Hsp_query-to>
      <Hsp_hit-from>169</Hsp_hit-from>
      <Hsp_hit-to>367</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>205</Hsp_align-len>
      <Hsp_qseq>RIPPHESVACVDEVLLGEHWAYAFLER-GCGDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALPEALSPKARCLIRDLLRRDPSERLSARDILHHP</Hsp_qseq>
      <Hsp_hseq>KLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNR-RIKIADF-GMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPS----DVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMPSNLSSEARDLISKILVIDPEKRITTQEILKHP</Hsp_hseq>
      <Hsp_midline>++  H +V  + EV   +   Y  LE    G+L  ++ +  +LPE EA   F Q V  V +CH   I  RDLK    +   ++R R+++     +  L   +  L    G P Y SPEI+      G  S    DVWS G++L+ +L G  PF++     L  +++ G+Y +P  LS +AR LI  +L  DP +R++ ++IL HP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>97.8265</Hsp_bit-score>
      <Hsp_score>242</Hsp_score>
      <Hsp_evalue>4.29686e-22</Hsp_evalue>
      <Hsp_query-from>565</Hsp_query-from>
      <Hsp_query-to>1059</Hsp_query-to>
      <Hsp_hit-from>128</Hsp_hit-from>
      <Hsp_hit-to>289</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>169</Hsp_align-len>
      <Hsp_qseq>LPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPT--ALFARIRRGQYALP--EALSPKARCLIRDLLRRDPSERLSARDILHHPWF</Hsp_qseq>
      <Hsp_hseq>LPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGM---AALETEGKLLETSCGSPHYAAPEIVS----GIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERRIKTRDILKHPLL</Hsp_hseq>
      <Hsp_midline>LPE EA R F Q +  V +CH  GIV RDLK    +   +  +++   G+     L ++   L    G P Y +PEI++       Y G A+DVWS GV+L+ +L G+ PF E +     L  ++++G++ +P  + +S +A+ LIR +L  DP  R+  RDIL HP  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.9005</Hsp_bit-score>
      <Hsp_score>237</Hsp_score>
      <Hsp_evalue>1.354e-21</Hsp_evalue>
      <Hsp_query-from>454</Hsp_query-from>
      <Hsp_query-to>1059</Hsp_query-to>
      <Hsp_hit-from>109</Hsp_hit-from>
      <Hsp_hit-to>313</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>211</Hsp_align-len>
      <Hsp_qseq>HESVACVDEVLLGEHWAYAFLE-RGCGDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPF---HESEPTA-----LFARIRRGQYALPEALSPKARCLIRDLLRRDPSERLSARDILHHPWF</Hsp_qseq>
      <Hsp_hseq>HPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGF--VNEFFEDNELMKTSCGSPCYAAPELVV---STKAYEARKADVWSCGVILYAMLAGYLPWDDDHEN-PTGDDIARLYKYITQTPLKFPEYITPIPRDLLRRILVPNPRRRINLQTIKRHVWL</Hsp_hseq>
      <Hsp_midline>H ++  ++EVL    +    LE    G+ + +++  +RL E  A RLF Q +S V++ H  G+V RDLKL   +    + + +   G   V     D++ +    G P Y +PE++    S+  Y  R ADVWS GV+LY ML G  P+   HE+ PT      L+  I +     PE ++P  R L+R +L  +P  R++ + I  H W </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.5153</Hsp_bit-score>
      <Hsp_score>236</Hsp_score>
      <Hsp_evalue>2.53456e-21</Hsp_evalue>
      <Hsp_query-from>439</Hsp_query-from>
      <Hsp_query-to>1059</Hsp_query-to>
      <Hsp_hit-from>81</Hsp_hit-from>
      <Hsp_hit-to>285</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>212</Hsp_align-len>
      <Hsp_qseq>FRIPPHESVACVDEVLLGEHWAYAFLERG-CGDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTA--LFARIRRGQYALPE--ALSPKARCLIRDLLRRDPSERLSARDILHHPWF</Hsp_qseq>
      <Hsp_hseq>MKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGM---AALQTDADLLETSCGSPHYAAPEIVS----GLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLL</Hsp_hseq>
      <Hsp_midline> ++  H +V  + +V    +  Y  LE    G+L + +     LPE EA   F Q +  + +CH  GIV RDLK    +      +++   G+     L +D D L    G P Y +PEI++       Y G A+DVWS GV+L+ +L G+ PF E       L  ++++GQ+ +P    +S  A+ LI  +L  DP +R+  RDIL HP  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.1301</Hsp_bit-score>
      <Hsp_score>235</Hsp_score>
      <Hsp_evalue>3.05234e-21</Hsp_evalue>
      <Hsp_query-from>454</Hsp_query-from>
      <Hsp_query-to>1059</Hsp_query-to>
      <Hsp_hit-from>109</Hsp_hit-from>
      <Hsp_hit-to>313</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>211</Hsp_align-len>
      <Hsp_qseq>HESVACVDEVLLGEHWAYAFLERGCG-DLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVF-RDEDRMRLRLEGLEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHE-------SEPTALFARIRRGQYALPEALSPKARCLIRDLLRRDPSERLSARDILHHPWF</Hsp_qseq>
      <Hsp_hseq>HPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVNEFC---SRNELMKTSCGSPCYAAPELVI---SAEPYEARKADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGRLYNYINSTPLKFPDYILPIPRDLLRRMLVSDPKKRINLKQIKKHEWL</Hsp_hseq>
      <Hsp_midline>H ++  ++EVL    +    LE  CG + + +++  +RL E  A RLF Q +S V + H  G+V RDLKL   +  ++E+ +      + + C   S ++ +    G P Y +PE++    S+  Y  R AD+WS GV+LY +L G  P+ +       S+   L+  I       P+ + P  R L+R +L  DP +R++ + I  H W </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>92.4337</Hsp_bit-score>
      <Hsp_score>228</Hsp_score>
      <Hsp_evalue>1.99982e-20</Hsp_evalue>
      <Hsp_query-from>529</Hsp_query-from>
      <Hsp_query-to>1071</Hsp_query-to>
      <Hsp_hit-from>164</Hsp_hit-from>
      <Hsp_hit-to>341</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>183</Hsp_align-len>
      <Hsp_qseq>GDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALP--EALSPKARCLIRDLLRRDPSERLSARDILHHPWFACDF</Hsp_qseq>
      <Hsp_hseq>GSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGL--AAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEV---DIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRDKPISDEGKILIRDILSLDPIERPSLTEIMDYVWFRGTF</Hsp_hseq>
      <Hsp_midline>G L   ++  K L E E      Q   A+ + H   ++ RDLKL    F     +++   GL    VL ++ +      G P Y++PE+L    S   +     D+WSLGVMLY +L+G+ PF   +   ++ RI+   ++ P  + +S + + LIRD+L  DP ER S  +I+ + WF   F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.8113</Hsp_bit-score>
      <Hsp_score>216</Hsp_score>
      <Hsp_evalue>1.71407e-19</Hsp_evalue>
      <Hsp_query-from>529</Hsp_query-from>
      <Hsp_query-to>1176</Hsp_query-to>
      <Hsp_hit-from>153</Hsp_hit-from>
      <Hsp_hit-to>373</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>231</Hsp_align-len>
      <Hsp_qseq>GDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALPEALSPK-----ARCLIRDLLRRDPSERLSARDILHHPWFA-CDFSXXXXXXXREP-------GCGQDAHSDQLVPEGLAH--DGEDPF</Hsp_qseq>
      <Hsp_hseq>GELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKIT-----DFGFAKEVQTVTWTLCGTPDYIAPEVITTKPYNKSV-----DWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFDQYPEEQLDYGIQGDDPY</Hsp_hseq>
      <Hsp_midline>G+L S +R  +R P   A     + + A+++ H H I+ RDLK    +      +++      D               G P Y++PE++T    +        D WSLGV++Y ML G  PF+++ P   + +I +G+   P    P      ++ +  DL RR  + +  +RDI  HPWF+   +    A     P       G G  +  DQ   E L +   G+DP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.2705</Hsp_bit-score>
      <Hsp_score>212</Hsp_score>
      <Hsp_evalue>1.04836e-18</Hsp_evalue>
      <Hsp_query-from>304</Hsp_query-from>
      <Hsp_query-to>1065</Hsp_query-to>
      <Hsp_hit-from>53</Hsp_hit-from>
      <Hsp_hit-to>301</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>119</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>268</Hsp_align-len>
      <Hsp_qseq>RAVNTHTGRE-----LVCKVRRSRRVCLGAVWVAVYARCVASYRDSLAAYFRIPPHESVACVDEVLLGEHWAYAF--LERGCGDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDE-DRMRLRLEGLEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALP------EALSPKARCLIRDLLRRDPSERLSARDILHHPWFAC</Hsp_qseq>
      <Hsp_hseq>QAKNTETGEDVAVKILIKKALKGNKVQLEALY------------DELDILQRLH-HPNIVAFKDWFESKDKFYIITQLAKG-GELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLT-----QDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAELLEDPWIIC</Hsp_hseq>
      <Hsp_midline>+A NT TG +     L+ K  +  +V L A++            D L    R+  H ++    +    +   Y    L +G G+L   +    +  EE+A R+  + +SAV + H   IV RDLK    ++ D+ D   L +        L SD++ L +  G   YV+PE+LT         G+  D+WS+GV+ YT+L G   F              G+Y +       +++S KA+  I   L  DPS+R +A ++L  PW  C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.8853</Hsp_bit-score>
      <Hsp_score>211</Hsp_score>
      <Hsp_evalue>1.05524e-18</Hsp_evalue>
      <Hsp_query-from>529</Hsp_query-from>
      <Hsp_query-to>1059</Hsp_query-to>
      <Hsp_hit-from>171</Hsp_hit-from>
      <Hsp_hit-to>342</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>182</Hsp_align-len>
      <Hsp_qseq>GDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALPEALSPKARCLIRDLLRRDPSERL-----SARDILHHPWF</Hsp_qseq>
      <Hsp_hseq>GELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYV-----PDVTYTLCGTPDYIAPEVVSTKPYNKSV-----DWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWF</Hsp_hseq>
      <Hsp_midline>G+L S +R  +R P   A     +   A+++ H   I+ RDLK    +      +++   G           D      G P Y++PE+++    +        D WS GV++Y ML G  PF+ S     +  I   +   P    P A+ L++ L+ RD SERL      + D+ +HPWF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.2629</Hsp_bit-score>
      <Hsp_score>199</Hsp_score>
      <Hsp_evalue>8.87956e-17</Hsp_evalue>
      <Hsp_query-from>529</Hsp_query-from>
      <Hsp_query-to>1059</Hsp_query-to>
      <Hsp_hit-from>209</Hsp_hit-from>
      <Hsp_hit-to>391</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>190</Hsp_align-len>
      <Hsp_qseq>GDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSLAEK-------------VGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALPEALSPKARCLIRDLLRRDPSERLSARDILHHPWF</Hsp_qseq>
      <Hsp_hseq>GDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILL--DKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRC-----DIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKIQYAFTAGFPQIVKDLVKKLLVRDPNDRLTIKQIKAHLFF</Hsp_hseq>
      <Hsp_midline>GD    ++    L E  A     Q + AVD  H  GI+ RD+K    +   +  M+++L       +L  +  + A+              VG   YVSPE+L    +  R      D+W+ G +LY ML G+ PF  +     F ++ + QYA         + L++ LL RDP++RL+ + I  H +F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.337</Hsp_bit-score>
      <Hsp_score>194</Hsp_score>
      <Hsp_evalue>2.62125e-16</Hsp_evalue>
      <Hsp_query-from>496</Hsp_query-from>
      <Hsp_query-to>1062</Hsp_query-to>
      <Hsp_hit-from>421</Hsp_hit-from>
      <Hsp_hit-to>603</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>193</Hsp_align-len>
      <Hsp_qseq>HWAYAFLERGCGDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLH-SDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALPEALSPKARCLIRDLLRRDPSERL---SARDILHHPWFA</Hsp_qseq>
      <Hsp_hseq>YFVLAFI--NGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGL---CKLNMKDDDKTDTFCGTPEYLAPELL-----LGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSRDPTRRLGYNGADEIRNHPFFS</Hsp_hseq>
      <Hsp_midline>++  AF+    G+L  H++   R     A     + + A+D+ H+  +V RDLK    +   +  + L   GL   C L+  DDD      G P Y++PE+L      G    +A D W+LGV+LY ML G  P+++ +   ++ +I +     P+     A+ L+  LL RDP+ RL    A +I +HP+F+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.1814</Hsp_bit-score>
      <Hsp_score>191</Hsp_score>
      <Hsp_evalue>3.2014e-16</Hsp_evalue>
      <Hsp_query-from>529</Hsp_query-from>
      <Hsp_query-to>1176</Hsp_query-to>
      <Hsp_hit-from>170</Hsp_hit-from>
      <Hsp_hit-to>390</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>231</Hsp_align-len>
      <Hsp_qseq>GDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALPEALSPKARCLIRDLLRRDPSERL-----SARDILHHPWFA----CDFSXXXXXXXREP----GCGQDAHSDQLVPEGLAH--DGEDPF</Hsp_qseq>
      <Hsp_hseq>GELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYV-----PDVTYTLCGTPDYIAPEVVSTKPYNKSI-----DWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGDTSQFDKYPEEDINYGVQGEDPY</Hsp_hseq>
      <Hsp_midline>G+L S +R  +R P   A     +   A+++ H   I+ RDLK    +      +++   G           D      G P Y++PE+++    +        D WS G+++Y ML G  PF++S     + +I   +   P   +   + L+  L+ RD S+RL        D+ +HPWF         +       EP    G G  +  D+   E + +   GEDP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.9518</Hsp_bit-score>
      <Hsp_score>193</Hsp_score>
      <Hsp_evalue>3.91036e-16</Hsp_evalue>
      <Hsp_query-from>529</Hsp_query-from>
      <Hsp_query-to>1059</Hsp_query-to>
      <Hsp_hit-from>279</Hsp_hit-from>
      <Hsp_hit-to>466</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>189</Hsp_align-len>
      <Hsp_qseq>GDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXX--------XXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQY---ALPEA-LSPKARCLIRDLLRRDPSERLSARDILHHPWF</Hsp_qseq>
      <Hsp_hseq>GDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDF-GLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGPLKDFRISEEARDFIDSLLQVDPNNRSTAAKALNHPWI</Hsp_hseq>
      <Hsp_midline>GDL   V A   + E+    +  Q ++A+ + H  GI  RDLK    +   +D + +++     +  +  +   +    G  AYV+PE++    +S                D+WS+G ++Y +L G  PF  S    L+ +I RG Y    L +  +S +AR  I  LL+ DP+ R +A   L+HPW </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.7962</Hsp_bit-score>
      <Hsp_score>190</Hsp_score>
      <Hsp_evalue>1.07273e-15</Hsp_evalue>
      <Hsp_query-from>529</Hsp_query-from>
      <Hsp_query-to>1062</Hsp_query-to>
      <Hsp_hit-from>498</Hsp_hit-from>
      <Hsp_hit-to>672</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>183</Hsp_align-len>
      <Hsp_qseq>GDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALP-EALSPKARCLIRDLLRRDPSERLSA----RDILHHPWFA</Hsp_qseq>
      <Hsp_hseq>GELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADL----KDRTNTFCGTTEYLAPELL----LDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFA</Hsp_hseq>
      <Hsp_midline>G+L  H++   R  E+ A     + V A++H H + IV RDLK    +      + L   GL    +     D      G   Y++PE+L           +  D WSLGV+++ M  G  PF       ++ +I  G+   P + LS + R  ++ LL R+P  RL A    R++  HP+FA</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.411</Hsp_bit-score>
      <Hsp_score>189</Hsp_score>
      <Hsp_evalue>1.07816e-15</Hsp_evalue>
      <Hsp_query-from>529</Hsp_query-from>
      <Hsp_query-to>1059</Hsp_query-to>
      <Hsp_hit-from>427</Hsp_hit-from>
      <Hsp_hit-to>599</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>181</Hsp_align-len>
      <Hsp_qseq>GDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLH-SDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALPEALSPKARCLIRDLLRRDPSERLSAR---DILHHPWF</Hsp_qseq>
      <Hsp_hseq>GELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGL---CKLNMKDNDKTDTFCGTPEYLAPEIL-----LGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAAKDLLIGLLSRDPSRRLGVNGTDEIRNHPFF</Hsp_hseq>
      <Hsp_midline>G+L  H++   R     +     + + A+D  H+  ++ RDLK    +   +  + L   GL   C L+  D+D      G P Y++PEIL      G+   +  D W+LG++LY M+ G  P+++     ++ +I +     P+   P A+ L+  LL RDPS RL      +I +HP+F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.0258</Hsp_bit-score>
      <Hsp_score>188</Hsp_score>
      <Hsp_evalue>2.12294e-15</Hsp_evalue>
      <Hsp_query-from>487</Hsp_query-from>
      <Hsp_query-to>1074</Hsp_query-to>
      <Hsp_hit-from>215</Hsp_hit-from>
      <Hsp_hit-to>403</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>196</Hsp_align-len>
      <Hsp_qseq>LGEHWAYAFLERGCGDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALPEALSPKARCLIRDLLRRDPSERLSARDILHHPWFACDFS</Hsp_qseq>
      <Hsp_hseq>LSNHFYMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNI---YDSRKQLHTFCGSLYFAAPELL----KANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKIKQGKVEYPQHLSIEVISLLSKMLVVDPKRRATLKQVVEHHWMVRGFN</Hsp_hseq>
      <Hsp_midline>L  H+   F     G L  ++     + E +A +      SA+ + H + IV RDLK+   +  D   +++   GL ++   +     L    G   + +PE+L     +  Y+G   DVWS GV+L+ ++ G+ PF +   + L  +I++G+   P+ LS +   L+  +L  DP  R + + ++ H W    F+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.8702</Hsp_bit-score>
      <Hsp_score>185</Hsp_score>
      <Hsp_evalue>5.33945e-15</Hsp_evalue>
      <Hsp_query-from>487</Hsp_query-from>
      <Hsp_query-to>1104</Hsp_query-to>
      <Hsp_hit-from>194</Hsp_hit-from>
      <Hsp_hit-to>394</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>216</Hsp_align-len>
      <Hsp_qseq>LGEHWAYAFLERGCGDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVC----VLHSDDDSL----AEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALPEALSPKARCLIRDLLRRDPSERLSARDILHHPWF--ACDFSXXXXXXXREP</Hsp_qseq>
      <Hsp_hseq>MSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELLKAQPYTGPEV---------------DIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYPSHLSIEVISLLTRMIVVDPLRRATLKNVVEHPWMNRGYDFKAPSYVPNRVP</Hsp_hseq>
      <Hsp_midline>+  H+   F     G L  ++     L E  A +      SA+ + H + IV RDLK+   +      +++   GL ++      LH+   SL     E +    Y  PE+               D+WS G++LY ++ G+ PF +   + L  +I++G+   P  LS +   L+  ++  DP  R + ++++ HPW     DF A + V  R P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.7146</Hsp_bit-score>
      <Hsp_score>182</Hsp_score>
      <Hsp_evalue>9.94668e-15</Hsp_evalue>
      <Hsp_query-from>460</Hsp_query-from>
      <Hsp_query-to>1059</Hsp_query-to>
      <Hsp_hit-from>239</Hsp_hit-from>
      <Hsp_hit-to>443</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>212</Hsp_align-len>
      <Hsp_qseq>SVACVDEVLLGEHWAYAFLERG-CGDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSLAEK-----------VGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALPEALSPKARCLIRDLLRRDPSERLSARDILHHPWF</Hsp_qseq>
      <Hsp_hseq>SVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGE--MKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRC-----DIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKVQYAFTPGFPLIIRDLVKKILVKNLDRRLTISQIKEHHFF</Hsp_hseq>
      <Hsp_midline>SV  +      E   Y  LE    GD  S ++    L E  A     Q + A+D+ H +GI+ RD+K    +   E  M+++L       +L+  ++S+++            VG   YVSPE+L    +  R      D+W+ G +L+ M+ G+ PF  +     F ++ + QYA         R L++ +L ++   RL+   I  H +F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.3294</Hsp_bit-score>
      <Hsp_score>181</Hsp_score>
      <Hsp_evalue>1.45287e-14</Hsp_evalue>
      <Hsp_query-from>478</Hsp_query-from>
      <Hsp_query-to>1059</Hsp_query-to>
      <Hsp_hit-from>99</Hsp_hit-from>
      <Hsp_hit-to>287</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>196</Hsp_align-len>
      <Hsp_qseq>EVLLGEHWAYAFLERGCG-DLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALPEALSP-KARCLIRDLLRRDPSERLSARDILHHPWF</Hsp_qseq>
      <Hsp_hseq>EVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTRECMTKT---TLETVCGTTVYMAPELI----ERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDAKVIPDDARDLISRLLAKNPGERPSLSQVLRHPFL</Hsp_hseq>
      <Hsp_midline>EV++ E   +  LE   G +L+ H+ + +R+   E   LF Q   AV + H    V RDLKL   +       +L   G    C+  +   +L    G   Y++PE++        Y G   D+WSLGV+LYT++ G  PF + +      +I   +      + P  AR LI  LL ++P ER S   +L HP+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>1.97856e-14</Hsp_evalue>
      <Hsp_query-from>259</Hsp_query-from>
      <Hsp_query-to>1059</Hsp_query-to>
      <Hsp_hit-from>209</Hsp_hit-from>
      <Hsp_hit-to>480</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>127</Hsp_positive>
      <Hsp_gaps>53</Hsp_gaps>
      <Hsp_align-len>296</Hsp_align-len>
      <Hsp_qseq>GHYVLLEPLEGQRMLRAVNTHTGRELVCKVRRSRRVCLGAVWVAVYARCVASYRDSLAAYFRIPPHESVACVDE----VLLGEHWAYAFLER-GCGDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFR---------------DEDRMRLRLE----GLEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHES-EPTALFARIRRGQYALP----EALSPKARCLIRDLLRRDPSERLSARDILHHPWF</Hsp_qseq>
      <Hsp_hseq>GHYALVK--------EAKNKKTGQQVAVKIFHAQQ--------NDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLC---GTPSYVAPEVLTKKGYTSKV-----DLWSAGVILYVCLCGFPPFSDQLGPPSLKEQILQAKYAFYSPYWDKIDDSVLHLISNLLVLNPDERYNIDEALNHPWF</Hsp_hseq>
      <Hsp_midline>GHY L++         A N  TG+++  K+  +++            +    +R+      R+     V  +D     +   +   Y  LE+   G+L   +     L ++E+  LF Q ++ + + H+  I+ RD+K    +                 DED + ++++    GL          ++L    G P+YV+PE+LT  G + +      D+WS GV+LY  L G  PF +   P +L  +I + +YA      + +      LI +LL  +P ER +  + L+HPWF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>4.97284e-14</Hsp_evalue>
      <Hsp_query-from>529</Hsp_query-from>
      <Hsp_query-to>1059</Hsp_query-to>
      <Hsp_hit-from>187</Hsp_hit-from>
      <Hsp_hit-to>355</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>177</Hsp_align-len>
      <Hsp_qseq>GDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALPEALSPKARCLIRDLLRRDPSERLSARDILHHPWF</Hsp_qseq>
      <Hsp_hseq>GEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGW---SIINPPENRRKTVCGTIDYLSPEMV-----ESREYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMPSNISQDAQDLILKLLKYDPKDRMRLGDVKMHPWI</Hsp_hseq>
      <Hsp_midline>G+++  +R      +  A+   +Q  +A+D+ H+  I+ RD+K    +    + ++L   G     +++  ++      G   Y+SPE++       R      D W+LGV+ + +L G  PF E      + RI      +P  +S  A+ LI  LL+ DP +R+   D+  HPW </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.8626</Hsp_bit-score>
      <Hsp_score>172</Hsp_score>
      <Hsp_evalue>2.08699e-13</Hsp_evalue>
      <Hsp_query-from>496</Hsp_query-from>
      <Hsp_query-to>1059</Hsp_query-to>
      <Hsp_hit-from>901</Hsp_hit-from>
      <Hsp_hit-to>1083</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>193</Hsp_align-len>
      <Hsp_qseq>HWAYAFLERGCGDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALPEALSPKARCLIRDLLRRDPSERLSA--RD---ILHHPWF</Hsp_qseq>
      <Hsp_hseq>YFAMEFI--GGGDLMWHVQN-QRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTF--CGTPEFMAPEIL-----KEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFF</Hsp_hseq>
      <Hsp_midline>++A  F+  G GDL  HV+  +RL    A     + + A+ + H +G++ RDLKL   +   E  +++   GL    + + +  S     G P +++PEIL       +   +A D W+ GV+LY ML+ Q PF   +   +F  I   +   P  ++ +   + + LL +DP +RL A  RD   ++  P+F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>7.84289e-13</Hsp_evalue>
      <Hsp_query-from>529</Hsp_query-from>
      <Hsp_query-to>1122</Hsp_query-to>
      <Hsp_hit-from>247</Hsp_hit-from>
      <Hsp_hit-to>465</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>219</Hsp_align-len>
      <Hsp_qseq>GDLHSHVRA---CKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVF-RDEDRMRLRLEGLEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXX------------DVWSLGVMLYTMLVGQYPFHE--SEPTAL-FARIRRGQYALPE--ALSPKARCLIRDLLRRDPSERLSARDILHHPWFACDFSXXXXXXXREPGCGQDA</Hsp_qseq>
      <Hsp_hseq>GDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGISPFYGDGSERSIIQNAKIGKLNFKLKQWDIVSDNAKSFVKDLLQTDVVKRLNSKQGLKHIWIAKHLSQLERLYYKKILCNNEG</Hsp_hseq>
      <Hsp_midline>GDL S++        + E E+  +  Q + A+++ H   IV RDLKL   +    E   R+ L        L+S+ + +   VG P Y +PE+          S   A            D+WSLGV+ + ML G  PF+   SE + +  A+I +  + L +   +S  A+  ++DLL+ D  +RL+++  L H W A   S    +  ++  C  + </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>9.30836e-13</Hsp_evalue>
      <Hsp_query-from>529</Hsp_query-from>
      <Hsp_query-to>1065</Hsp_query-to>
      <Hsp_hit-from>131</Hsp_hit-from>
      <Hsp_hit-to>311</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>186</Hsp_align-len>
      <Hsp_qseq>GDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMR-LRLEGLEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALP------EALSPKARCLIRDLLRRDPSERLSARDILHHPWFAC</Hsp_qseq>
      <Hsp_hseq>GELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGHGKPC-----DIWSIGVITYTLLCGYSPFIAESVEGFMEECTASRYPVTFHMPYWDNISIDVKRFILKALRLNPADRPTATELLDDPWITS</Hsp_hseq>
      <Hsp_midline>G+L   + +  +  E +A  +  Q + AV++ H   +V RDLK    ++ D+     L +        L  ++D + +  G   YV+PE+LT  G          D+WS+GV+ YT+L G  PF               +Y +       + +S   +  I   LR +P++R +A ++L  PW   </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>3.85621e-12</Hsp_evalue>
      <Hsp_query-from>529</Hsp_query-from>
      <Hsp_query-to>1056</Hsp_query-to>
      <Hsp_hit-from>219</Hsp_hit-from>
      <Hsp_hit-to>413</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>206</Hsp_align-len>
      <Hsp_qseq>GDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFR-------DEDRMRLRLEGLEDVCVLHSD----------DDSLAEKV---------GCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALP----EALSPKARCLIRDLLRRDPSERLSARDILHHPW</Hsp_qseq>
      <Hsp_hseq>GEIFDRIVQLTCFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQK------EDEFTLGVGGGGIGLVKLMDFGLAKKLRNNTAKTPCGTIEYVASEVFTSKRYSMKV-----DMWSIGCVLFTLLCGYPPFYEKNEKTLLKKISRGDYEFLAPWWDNISSGAKNAVTHLLEVDPNKRYDIDDFLNDPW</Hsp_hseq>
      <Hsp_midline>G++   +       E+ A  +  Q   A+ H H  GIV RD+K    +F        D D  +      ED   L             D  LA+K+         G   YV+ E+ T+   S +      D+WS+G +L+T+L G  PF+E     L  +I RG Y       + +S  A+  +  LL  DP++R    D L+ PW</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YFL033C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:69115:74427:-1 gene:YFL033C transcript:YFL033C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM15 description:Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase [Source:SGD;Acc:S000001861]</Hit_def>
  <Hit_accession>YFL033C</Hit_accession>
  <Hit_len>1770</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>3.90306e-12</Hsp_evalue>
      <Hsp_query-from>718</Hsp_query-from>
      <Hsp_query-to>1059</Hsp_query-to>
      <Hsp_hit-from>1132</Hsp_hit-from>
      <Hsp_hit-to>1254</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>127</Hsp_align-len>
      <Hsp_qseq>DVCVLHSDDDSLAEKV-GCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALPE---------ALSPKARCLIRDLLRRDPSERLSAR---DILHHPWF</Hsp_qseq>
      <Hsp_hseq>DLALFYPDDSKQNKKFFGTPDYLAPETI----EGKGEDNKQCDWWSVGCIFFELLLGYPPFHAETPDAVFKKILSGVIQWPEFKNEEEEREFLTPEAKDLIEKLLVVDPAKRLGAKGIQEIKDHPYF</Hsp_hseq>
      <Hsp_midline>D+ + + DD    +K  G P Y++PE +           +  D WS+G + + +L+G  PFH   P A+F +I  G    PE          L+P+A+ LI  LL  DP++RL A+   +I  HP+F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>1.33417e-11</Hsp_evalue>
      <Hsp_query-from>454</Hsp_query-from>
      <Hsp_query-to>1056</Hsp_query-to>
      <Hsp_hit-from>75</Hsp_hit-from>
      <Hsp_hit-to>280</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>214</Hsp_align-len>
      <Hsp_qseq>HESVACVDEVLLGEHWAYAFLERG-CGDLHSHVRACKRLPEEEAARLFHQAVSAVDHCH-QHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSL---AEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFH----ESEPTALF----ARIRRGQYALPEALSPKARCLIRDLLRRDPSERLSARDILHHPW</Hsp_qseq>
      <Hsp_hseq>HPNVLRLIDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGL--ASQFRRKDGTLRVSMDQRGSPPYMAPEVL---YSEEGYYADRTDIWSIGILLFVLLTGQTPWELPSLENEDFVFFIENDGNLNWGPWSKIEFTHLN---LLRKILQPDPNKRVTLKALKLHPW</Hsp_hseq>
      <Hsp_midline>H +V  + +  + + + +  LE    GDL   +     +  + A   F Q VSA+++ H + G+  RD+K    +      ++L   GL         D +L    ++ G P Y++PE+L    S   Y     D+WS+G++L+ +L GQ P+     E+E    F      +  G ++  E        L+R +L+ DP++R++ + +  HPW</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>1.73071e-11</Hsp_evalue>
      <Hsp_query-from>334</Hsp_query-from>
      <Hsp_query-to>1065</Hsp_query-to>
      <Hsp_hit-from>1122</Hsp_hit-from>
      <Hsp_hit-to>1356</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>250</Hsp_align-len>
      <Hsp_qseq>LVCKVRRSRRVCLGAVWVAVYARCVASYRDSLAAYFRIPPHESVACVDEVLLGEHWAYAFL----ERGCGDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALPEALSPKARC--LIRDLLRRDPSERLSARDILHHPWFAC</Hsp_qseq>
      <Hsp_hseq>VVIKMIFKERILVDT-WVRDRKLGTIPSEIQIMATLNKKPHENILRLLDFFEDDDYYYIETPVHGETGCIDLFDLIEFKTNMTEFEAKLIFKQVVAGIKHLHDQGIVHRDIKDENVIVDSKGFVKIIDFG----SAAYVKSGPFDVFVGTIDYAAPEVL----GGNPYEGQPQDIWAIGILLYTVVFKENPFYNID------EILEGDLKFNNAEEVSEDCIELIKSILNRCVPKRPTIDDINNDKWLVI</Hsp_hseq>
      <Hsp_midline>+V K+    R+ +   WV             + A     PHE++  + +    + + Y       E GC DL   +     + E EA  +F Q V+ + H H  GIV RD+K    +   +  +++   G       +         VG   Y +PE+L        Y G+  D+W++G++LYT++  + PF+  +       I  G      A      C  LI+ +L R   +R +  DI +  W   </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>6.30973e-11</Hsp_evalue>
      <Hsp_query-from>544</Hsp_query-from>
      <Hsp_query-to>1059</Hsp_query-to>
      <Hsp_hit-from>414</Hsp_hit-from>
      <Hsp_hit-to>602</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>194</Hsp_align-len>
      <Hsp_qseq>HVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRL------------RLEGLEDVCVLH----SDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALP--EALSPKARCLIRDLLRRDPSERLSAR----DILHHPWF</Hsp_qseq>
      <Hsp_hseq>QTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVI-----RGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKFPHDKEVSKNCKDLIKKLLNKNEAKRLGSKSGAADIKRHPFF</Hsp_hseq>
      <Hsp_midline>  R  K + EE+A     + V+A+++ H  G + RDLK    +      + L            +   ++D   L     SD       VG   Y++PE++      G     A D W+LG+++Y ML G  PF        F+ I       P  + +S   + LI+ LL ++ ++RL ++    DI  HP+F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>1.39663e-10</Hsp_evalue>
      <Hsp_query-from>517</Hsp_query-from>
      <Hsp_query-to>1059</Hsp_query-to>
      <Hsp_hit-from>931</Hsp_hit-from>
      <Hsp_hit-to>1099</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>183</Hsp_align-len>
      <Hsp_qseq>ERGCGDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQ--YALPEALSPKARCLIRDLLRRDPSERLSARDILHHPWF</Hsp_qseq>
      <Hsp_hseq>ETGSIDLFDVIEFKKDMVEHEAKLVFKQVVASIKHLHDQGIVHRDIKDENVIVDSHGFVKLIDFG----SAAYIKSGPFDVFVGTMDYAAPEVL----GGSSYKGKPQDIWALGVLLYTIIYKENPYYNID------EILEGELRFDKSEHVSEECISLIKRILTREVDKRPTIDEIYEDKWL</Hsp_hseq>
      <Hsp_midline>E G  DL   +   K + E EA  +F Q V+++ H H  GIV RD+K    +      ++L   G       +         VG   Y +PE+L        Y G+  D+W+LGV+LYT++  + P++  +       I  G+  +   E +S +   LI+ +L R+  +R +  +I    W </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>2.47986e-10</Hsp_evalue>
      <Hsp_query-from>598</Hsp_query-from>
      <Hsp_query-to>1062</Hsp_query-to>
      <Hsp_hit-from>121</Hsp_hit-from>
      <Hsp_hit-to>294</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>179</Hsp_align-len>
      <Hsp_qseq>QAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLE---------DVCVLHSDDD------SLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYAL---------PEALSPKARCLIRDLLRRDPSERLSARDILHHPWFA</Hsp_qseq>
      <Hsp_hseq>QLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELL-----LYNQCGYGSDIWALGCMIYQFVQGQPPFRGENELKTFEKIVALDYPWGPNNRINNSTSPINPLVINLVQKILVIEVNERISLEQIKRHPYFS</Hsp_hseq>
      <Hsp_midline>Q + A++  H HGI+ RDLK    +   + R+ +   G           D    +SD +      + A  VG   YVSPE+L          G  +D+W+LG M+Y  + GQ PF        F +I    Y              ++P    L++ +L  + +ER+S   I  HP+F+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>2.09139e-09</Hsp_evalue>
      <Hsp_query-from>574</Hsp_query-from>
      <Hsp_query-to>1059</Hsp_query-to>
      <Hsp_hit-from>810</Hsp_hit-from>
      <Hsp_hit-to>981</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>180</Hsp_align-len>
      <Hsp_qseq>EEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDR-MRLRLEGLE-------DVCVLHSDD-----DSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHES-EPTALFARIRRGQYALPEALSPKA----RCLIRDLLRRDPSERLSARDILHHPWF</Hsp_qseq>
      <Hsp_hseq>DEYWRLFRQILEALSYIHSQGIIHRDLKPMN-IFIDESRNVKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVLD----GTGHYNEKIDMYSLGIIFFEMI---YPFSTGMERVNILKKLRSVSIEFPPDFDDNKMKVEKKIIRLLIDHDPNKRPGARTLLNSGWL</Hsp_hseq>
      <Hsp_midline>+E  RLF Q + A+ + H  GI+ RDLK    +F DE R +++   GL        D+  L S +     D+L   +G   YV+ E+L        +     D++SLG++ + M+   YPF    E   +  ++R      P           + +IR L+  DP++R  AR +L+  W </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>3.23739e-09</Hsp_evalue>
      <Hsp_query-from>574</Hsp_query-from>
      <Hsp_query-to>1059</Hsp_query-to>
      <Hsp_hit-from>595</Hsp_hit-from>
      <Hsp_hit-to>777</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>188</Hsp_align-len>
      <Hsp_qseq>EEAARLFHQAVSA-VDHCHQHGIVLRDLKLRKFVFRDEDRMRLR---------------LEGLEDVCVLH----SDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALPEA--LSPKARCLIRDLLRRDPSERL----SARDILHHPWF</Hsp_qseq>
      <Hsp_hseq>EDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVI-----RGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKNEVSFPNNNEISRTCKDLIKKLLTKNESKRLGCKMGAADVKKHPFF</Hsp_hseq>
      <Hsp_midline>E+ AR +   V+A +++ H  G + RDLK    +      + L                ++G     ++     SD       VG   Y++PE++      G     A D W+LG+++Y ML G  PF        F  I + + + P    +S   + LI+ LL ++ S+RL     A D+  HP+F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>3.55632e-09</Hsp_evalue>
      <Hsp_query-from>565</Hsp_query-from>
      <Hsp_query-to>1068</Hsp_query-to>
      <Hsp_hit-from>665</Hsp_hit-from>
      <Hsp_hit-to>830</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>174</Hsp_align-len>
      <Hsp_qseq>LPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSL-AEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEP-TALFARIRRGQYAL--PEALSPKARCLIRDLLRRDPSERLSARDILHHPWF--ACD</Hsp_qseq>
      <Hsp_hseq>LTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGF---CARLTDKRSKRATMVGTPYWMAPEVV-----KQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATNGTPKLKHPESLSLEIKRFLSVCLCVDVRYRASTEELLHHGFFNMACD</Hsp_hseq>
      <Hsp_midline>L E + A +  +    +   H   I+ RD+K    +     R+++   G    C   +D  S  A  VG P +++PE++       R      DVWSLG+M   ML G+ P+   +P  AL+     G   L  PE+LS + +  +   L  D   R S  ++LHH +F  ACD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>3.73229e-09</Hsp_evalue>
      <Hsp_query-from>565</Hsp_query-from>
      <Hsp_query-to>1044</Hsp_query-to>
      <Hsp_hit-from>479</Hsp_hit-from>
      <Hsp_hit-to>634</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>164</Hsp_align-len>
      <Hsp_qseq>LPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSL-AEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEP-TALFARIRRGQYAL--PEALSPKARCLIRDLLRRDPSERLSARDIL</Hsp_qseq>
      <Hsp_hseq>LNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGF---CVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKV-----DVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANNGSPKLRHPESVSKQTKQFLDACLQVNVESRASVRKLL</Hsp_hseq>
      <Hsp_midline>L E + A +  +    +   H   I+ RD+K    +   +  +++   G    CV  ++  S  A  VG P +++PEI+   G   +      DVWSLG+ML  M+ G+ P+   +P  AL+     G   L  PE++S + +  +   L+ +   R S R +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>4.49034e-09</Hsp_evalue>
      <Hsp_query-from>481</Hsp_query-from>
      <Hsp_query-to>1062</Hsp_query-to>
      <Hsp_hit-from>685</Hsp_hit-from>
      <Hsp_hit-to>872</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>198</Hsp_align-len>
      <Hsp_qseq>VLLGEHWAYAFLERGCGDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGL-EDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPT-ALFARIRRGQYAL--PEALSPKARCLIRDLLRRDPSERLSARDILHHPWFA</Hsp_qseq>
      <Hsp_hseq>VLKGDLWVIMEYMEG-GSLTDVVTHC-ILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTM---VGTPYWMAPEVVSRKEYGPKV-----DIWSLGIMIIEMIEGEPPYLNETPLRALYLIATNGTPKLKEPENLSSSLKKFLDWCLCVEPEDRASATELLHDEYIT</Hsp_hseq>
      <Hsp_midline>VL G+ W       G G L   V  C  L E +   +  + +S ++  H  G++ RD+K    +   E  ++L   G    +  L+    ++   VG P +++PE+++      +      D+WSLG+M+  M+ G+ P+    P  AL+     G   L  PE LS   +  +   L  +P +R SA ++LH  +  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>5.21128e-09</Hsp_evalue>
      <Hsp_query-from>550</Hsp_query-from>
      <Hsp_query-to>1056</Hsp_query-to>
      <Hsp_hit-from>113</Hsp_hit-from>
      <Hsp_hit-to>271</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>174</Hsp_align-len>
      <Hsp_qseq>RACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALPEALSPK-----ARCLIRDLLRRDPSERLSARDILHHPW</Hsp_qseq>
      <Hsp_hseq>RSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVS--TIVNSSALTLA---GTLNWMAPEIL-----GNRGASTLSDIWSLGATVVEMLTKNPPYHNLTDANIYYAVENDTYYPPSSFSEPLKDFLSKCFVKNMYKRPTADQL-----LKHVW</Hsp_hseq>
      <Hsp_midline>R+   L E E+     Q +  + + H  G++ RD+K    +   ++ ++L   G+    +++S   +LA   G   +++PEIL       R +   +D+WSLG  +  ML    P+H      ++  +    Y  P + S       ++C ++++ +R  +++L     L H W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>5.3814e-09</Hsp_evalue>
      <Hsp_query-from>529</Hsp_query-from>
      <Hsp_query-to>1065</Hsp_query-to>
      <Hsp_hit-from>273</Hsp_hit-from>
      <Hsp_hit-to>480</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>213</Hsp_align-len>
      <Hsp_qseq>GDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVF--------------RDEDRMRLRLEGL-------EDVCVLHSDDDSLAEKV---------GCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYAL--P--EALSPKARCLIRDLLRRDPSERLSARDILHHPWFAC</Hsp_qseq>
      <Hsp_hseq>GEIFGEIVRLTYFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKNTKTPCGTVGYTAPEVV-----KDEHYSMKVDMWGIGCVLYTMLCGFPPFYDEKIDTLTEKISRGEYTFLKPWWDEISAGAKNAVAKLLELEPSKRYDIDQFLDDPWLNT</Hsp_hseq>
      <Hsp_midline>G++   +       E+ +  +  Q   AV H H  G+V RD+K    +F              + +D      EG+         + ++   D  L++++         G   Y +PE++        +     D+W +G +LYTML G  PF++ +   L  +I RG+Y    P  + +S  A+  +  LL  +PS+R      L  PW   </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>6.33746e-09</Hsp_evalue>
      <Hsp_query-from>523</Hsp_query-from>
      <Hsp_query-to>1044</Hsp_query-to>
      <Hsp_hit-from>100</Hsp_hit-from>
      <Hsp_hit-to>267</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>177</Hsp_align-len>
      <Hsp_qseq>GCGDL--HSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARI-RRGQYALPEALSPKARCLIRDLLRRDPSERLSARDIL</Hsp_qseq>
      <Hsp_hseq>SCSDLLKRSYVNG---LPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRDTF---VGTPYWMAPEVVC---CEVDGYNEKADIWSLGITTYELLKGLPPLSKYDPMKVMTNLPKRKPPKLQGPFSDAAKDFVAGCLVKTPADRPSAYNLL</Hsp_hseq>
      <Hsp_midline> C DL   S+V     LPEE+ + + H+    + + H+   + RD+K    +  +E  ++L   G+          D+    VG P +++PE++             AD+WSLG+  Y +L G  P  + +P  +   + +R    L    S  A+  +   L + P++R SA ++L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>1.00212e-08</Hsp_evalue>
      <Hsp_query-from>529</Hsp_query-from>
      <Hsp_query-to>1023</Hsp_query-to>
      <Hsp_hit-from>237</Hsp_hit-from>
      <Hsp_hit-to>406</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>175</Hsp_align-len>
      <Hsp_qseq>GDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGL-----EDVCVLHSDD---DSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYA--LPEALSPKARCLIRDLLRRDPSER</Hsp_qseq>
      <Hsp_hseq>GELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEIL-----LGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIPFYLSEGMKDILNALLKKETAKR</Hsp_hseq>
      <Hsp_midline>G+L  H++    L E   +    +   A+   H  G+V RDLK    +      + L   GL      D  V   D    ++L   +G P Y +PEIL      G+   +  D +SLG +LY MLVG+ P+  S    +  +I++ +    +P  LS   + ++  LL+++ ++R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>9.67674e-08</Hsp_evalue>
      <Hsp_query-from>742</Hsp_query-from>
      <Hsp_query-to>1074</Hsp_query-to>
      <Hsp_hit-from>220</Hsp_hit-from>
      <Hsp_hit-to>330</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>116</Hsp_align-len>
      <Hsp_qseq>DDSLAEKV-GCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQ--YALPE--ALSPKARCLIRDLLRRDPSERLSARDILHHPWFACDFS</Hsp_qseq>
      <Hsp_hseq>NTSLAETLCGSPLYMAPEILNYQKYNAKA-----DLWSVGTVVFEMCCGTPPFRASNHLELFKKIKRANDVITFPSYCNIEPELKELICSLLTFDPAQRIGFEEFFANKVVNEDLS</Hsp_hseq>
      <Hsp_midline>+ SLAE + G P Y++PEIL     + +      D+WS+G +++ M  G  PF  S    LF +I+R       P    + P+ + LI  LL  DP++R+   +   +     D S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>1.41124e-07</Hsp_evalue>
      <Hsp_query-from>427</Hsp_query-from>
      <Hsp_query-to>1050</Hsp_query-to>
      <Hsp_hit-from>239</Hsp_hit-from>
      <Hsp_hit-to>463</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>236</Hsp_align-len>
      <Hsp_qseq>LAAYFRIPPHESVACVDEVLLGEHWAYAFL----ERGCGDLHSHVRACKRL-------------PEEEAARLFHQAVSAVDHCH-QHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSLAEK-VGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPF--HESEPTALFARIRRGQYALPEALSPKARCLIRDLLR-------RDPSERLSARDILHH</Hsp_qseq>
      <Hsp_hseq>LSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKLI-----NSIADTFVGTSTYMSPERI-----QGNVYSIKGDVWSLGLMIIELVTGEFPLGGHNDTPDGILDLLQR-IVNEPSPRLPKDRIYSKEMTDFVNRCCIKNERERSSIHELLHH</Hsp_hseq>
      <Hsp_midline>L+    + PHE++         +H     +       CG L   +   KR               E   +++ +  ++ +DH + Q+ I+ RD+K    +   + +++L   G+    +     +S+A+  VG   Y+SPE +      G       DVWSLG+M+  ++ G++P   H   P  +   ++R     P    PK R   +++         ++  ER S  ++LHH</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>1.63458e-07</Hsp_evalue>
      <Hsp_query-from>562</Hsp_query-from>
      <Hsp_query-to>1059</Hsp_query-to>
      <Hsp_hit-from>313</Hsp_hit-from>
      <Hsp_hit-to>481</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>179</Hsp_align-len>
      <Hsp_qseq>RLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSLAEK-VGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIR------------RGQYALPEALSPKARCLIRDLLRRDPSERLSARDILHHPWF</Hsp_qseq>
      <Hsp_hseq>RISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFGVSGEAV-----NSLAMTFTGTSFYMAPERI-----QGQPYSVTCDVWSLGLTLLEVAGGRFPFESDKITQNVAPIELLTMILTFSPQLKDEPELDISWSKTFRSFIDYCLKKDARERPSPRQMLKHPWI</Hsp_hseq>
      <Hsp_midline>R+ E    ++    +  + + H+  ++ RD+K +  +  ++  ++L   G+    V     +SLA    G   Y++PE +      G+      DVWSLG+ L  +  G++PF   + T   A I             + +  L  + S   R  I   L++D  ER S R +L HPW </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>1.69837e-07</Hsp_evalue>
      <Hsp_query-from>529</Hsp_query-from>
      <Hsp_query-to>1059</Hsp_query-to>
      <Hsp_hit-from>539</Hsp_hit-from>
      <Hsp_hit-to>712</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>179</Hsp_align-len>
      <Hsp_qseq>GDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGL-EDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHE-SEPTALFARIRRGQYALPEALSPKARCLIRDLLRRDPSERLSARDILHHPWF</Hsp_qseq>
      <Hsp_hseq>GSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVV-----KQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKIGTNTTPEIPSWATSEGKNFLRKAFELDYQYRPSALELLQHPWL</Hsp_hseq>
      <Hsp_midline>G + S +       E        Q +  V + H+  I+ RD+K    +   +  +++   G+ + +  L+   +  A   G   ++SPE++         +   AD+WS G ++  M  G++PF + S+  A+F         +P   + + +  +R     D   R SA ++L HPW </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>1.74165e-07</Hsp_evalue>
      <Hsp_query-from>562</Hsp_query-from>
      <Hsp_query-to>1059</Hsp_query-to>
      <Hsp_hit-from>320</Hsp_hit-from>
      <Hsp_hit-to>488</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>179</Hsp_align-len>
      <Hsp_qseq>RLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDDSLAEK-VGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYAL---------PEA---LSPKARCLIRDLLRRDPSERLSARDILHHPWF</Hsp_qseq>
      <Hsp_hseq>RISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVSGEAV-----NSLATTFTGTSFYMAPERI-----QGQPYSVTSDVWSLGLTILEVANGKFPCSSEKMAANIAPFELLMWILTFTPELKDEPESNIIWSPSFKSFIDYCLKKDSRERPSPRQMINHPWI</Hsp_hseq>
      <Hsp_midline>R+ E+   ++    +  + + H+  ++ RD+K +  +  +  +++L   G+    V     +SLA    G   Y++PE +      G+     +DVWSLG+ +  +  G++P    +  A  A      + L         PE+    SP  +  I   L++D  ER S R +++HPW </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>2.49028e-07</Hsp_evalue>
      <Hsp_query-from>574</Hsp_query-from>
      <Hsp_query-to>957</Hsp_query-to>
      <Hsp_hit-from>164</Hsp_hit-from>
      <Hsp_hit-to>296</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>135</Hsp_align-len>
      <Hsp_qseq>EEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGL-----EDVCVLHSDDDSLAEK--VGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALP</Hsp_qseq>
      <Hsp_hseq>QQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAI--DIWSLGVTIYCLLFGKLPFNANSGLELFDSIINKPLEFP</Hsp_hseq>
      <Hsp_midline>+++ ++    VS +++ H  GI  RD+K    +      +++   G+          + S  + L +   +G PA+ +PE+ +        S    D+WSLGV +Y +L G+ PF+ +    LF  I       P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YMR291W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:852630:854390:1 gene:YMR291W transcript:YMR291W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TDA1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000004905]</Hit_def>
  <Hit_accession>YMR291W</Hit_accession>
  <Hit_len>586</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>2.87457e-07</Hsp_evalue>
      <Hsp_query-from>511</Hsp_query-from>
      <Hsp_query-to>1101</Hsp_query-to>
      <Hsp_hit-from>145</Hsp_hit-from>
      <Hsp_hit-to>365</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>233</Hsp_align-len>
      <Hsp_qseq>FLERGCGDLHSHVRA-CKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFR---DEDRMRLRLEGLEDV--------CVL----------HSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXX---------XDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALPEAL--SPKAR---CLIRDLLRRDPSERLSARDILHHPWFACDFSXXXXXXXRE</Hsp_qseq>
      <Hsp_hseq>IVENQCLDLETQVTSYCACL------------VSVLEFLHSQGIVHRDLKAENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLVLADFGLAAEYNTSKVNSLKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGCPVDIWALGVLTYFMAFGYTPFDCTTDDETLECISKCDYYVDEQMMHDPKYEQFWNFVQCCFTIDPAVRRSAKNLKQHPFIKDYFATSNSLNTKD</Hsp_hseq>
      <Hsp_midline> +E  C DL + V + C  L            VS ++  H  GIV RDLK    +FR   +E+   L+ E   D          VL           S  +SL E VG  +Y++PEI+   G       +           D+W+LGV+ Y M  G  PF  +        I +  Y + E +   PK       ++     DP+ R SA+++  HP+    F+ + ++  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>3.1056e-07</Hsp_evalue>
      <Hsp_query-from>526</Hsp_query-from>
      <Hsp_query-to>1056</Hsp_query-to>
      <Hsp_hit-from>312</Hsp_hit-from>
      <Hsp_hit-to>507</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>202</Hsp_align-len>
      <Hsp_qseq>CGDLHSHVRA-CKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLR----KFVFRDEDRMR-------LRLEGLED--VCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTAL-----------FARIRRGQYALPEALSPKARCLIRDLLRRDPSERLSARDILHHPW</Hsp_qseq>
      <Hsp_hseq>AGDLLAAVMARNGRLEAWLIQRIFTEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLCKKIENNEMCTARCGSEDYVSPEIL----MGVPYDGHLSDTWALGVILYSLFEDRLPF-DPPPNASARQRSRATSHRIARFDWRWYRLSDYKTNVGKQIVENTLTRK-NQRWSINEIYESPF</Hsp_hseq>
      <Hsp_midline> GDL + V A   RL      R+F + V AV + H++ I+ RDLKL     K+ F D +  R            L D  +C    +++    + G   YVSPEIL        Y G  +D W+LGV+LY++   + PF +  P A             AR     Y L +  +   + ++ + L R  ++R S  +I   P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YKL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:347214:349136:-1 gene:YKL048C transcript:YKL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ELM1 description:Serine/threonine protein kinase; regulates the orientation checkpoint, the morphogenesis checkpoint and the metabolic switch from fermentative to oxidative metabolism by phosphorylating the activation loop of Kin4p, Hsl1p and Snf4p respectively; cooperates with Hsl7p in recruiting Hsl1p to the septin ring, a prerequisite for subsequent recruitment, phosphorylation, and degradation of Swe1p; forms part of the bud neck ring; regulates cytokinesis [Source:SGD;Acc:S000001531]</Hit_def>
  <Hit_accession>YKL048C</Hit_accession>
  <Hit_len>640</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>3.80807e-07</Hsp_evalue>
      <Hsp_query-from>580</Hsp_query-from>
      <Hsp_query-to>1044</Hsp_query-to>
      <Hsp_hit-from>236</Hsp_hit-from>
      <Hsp_hit-to>403</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>172</Hsp_align-len>
      <Hsp_qseq>AARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDV--CVL------HSDDD-------SLAEKVGCPAYVSPEI--LTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALPEALSPKARCLIRDLLRRDPSERLSARDIL</Hsp_qseq>
      <Hsp_hseq>AKKILEDMTKGLEYLHSQGCIHRDIKPSNILLDEEEK----VAKLSDFGSCIFTPQSLPFSDANFEDCFQRELNKIVGTPAFIAPELCHLGNSKRDFVTDGFKLDIWSLGVTLYCLLYNELPFFGENEFETYHKIIEVSLSSKINGNTLNDLVIKRLLEKDVTLRISIQDLV</Hsp_hseq>
      <Hsp_midline>A ++       +++ H  G + RD+K    +  +E++    +  L D   C+        SD +        L + VG PA+++PE+  L          G   D+WSLGV LY +L  + PF        + +I     +     +     +I+ LL +D + R+S +D++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YJR059W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:545787:548243:1 gene:YJR059W transcript:YJR059W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK2 description:Serine/threonine protein kinase; involved in regulation of ion transport across plasma membrane; carboxyl terminus is essential for glucose-dependent Pma1p activation via phosphorylation of Pma1p-Ser899; enhances spermine uptake; PTK2 has a paralog, PTK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003820]</Hit_def>
  <Hit_accession>YJR059W</Hit_accession>
  <Hit_len>818</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>4.28624e-07</Hsp_evalue>
      <Hsp_query-from>499</Hsp_query-from>
      <Hsp_query-to>906</Hsp_query-to>
      <Hsp_hit-from>337</Hsp_hit-from>
      <Hsp_hit-to>485</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>150</Hsp_align-len>
      <Hsp_qseq>WAYAFLERGCGDLHSHVR--ACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLED-VCVLHSDDDSLAEK----VGCPAYVSPEILTXXXXX-------XXXXXXXXDVWSLGVMLYTMLVGQYPFHES</Hsp_qseq>
      <Hsp_hseq>WGF-IMELGVKDLFQLMERTGWKNVPFNEKYCLFKQVAQGIKFCHDNGIAHRDLKPENVLISKEGICKLTDFGISDWYHVIPHDYTSPVKTCQGMIGSPPYTPPEVMYFDAKKHYPEKFQKPYNPLAMDSYALGIMLITMINNIIPFIDS</Hsp_hseq>
      <Hsp_midline>W +  +E G  DL   +     K +P  E   LF Q    +  CH +GI  RDLK    +   E   +L   G+ D   V+  D  S  +     +G P Y  PE++               Y+  A D ++LG+ML TM+    PF +S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YBR059C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:356861:360187:-1 gene:YBR059C transcript:YBR059C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AKL1 description:Ser-Thr protein kinase; member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization [Source:SGD;Acc:S000000263]</Hit_def>
  <Hit_accession>YBR059C</Hit_accession>
  <Hit_len>1108</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>6.45302e-07</Hsp_evalue>
      <Hsp_query-from>550</Hsp_query-from>
      <Hsp_query-to>1050</Hsp_query-to>
      <Hsp_hit-from>146</Hsp_hit-from>
      <Hsp_hit-to>316</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>177</Hsp_align-len>
      <Hsp_qseq>RACKRLPEEEAARLFHQAVSAVDHCHQHGIVL--RDLKLRKFVFRDEDRMRLRLEGLEDVC----VLHSDDDSLAEKV---GCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALP-EALSPKARCLIRDLLRRDPSERLSARDILHH</Hsp_qseq>
      <Hsp_hseq>RLSTKLTEAEIVKIMYDVALSISQMHYLPVSLIHRDIKIENVLVDAKNNFKLADFGSTSTCFPIVTTHQDIALLTQNIYVHTTPQYRSPEMI--DLYRCLPINEKSDIWALGVFLYKLLFFTTPF---EMTGQFA-ILHSKYEFPVNKYSSKLINLIIIMLAENPNLRPNIYQVLYH</Hsp_hseq>
      <Hsp_midline>R   +L E E  ++ +    ++   H   + L  RD+K+   +   ++  +L   G    C      H D   L + +     P Y SPE++             +D+W+LGV LY +L    PF   E T  FA I   +Y  P    S K   LI  +L  +P+ R +   +L+H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>8.40698e-07</Hsp_evalue>
      <Hsp_query-from>529</Hsp_query-from>
      <Hsp_query-to>1056</Hsp_query-to>
      <Hsp_hit-from>409</Hsp_hit-from>
      <Hsp_hit-to>589</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>186</Hsp_align-len>
      <Hsp_qseq>GDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCVLHSDDD-SLAEKV-GCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALF------ARIRRGQYALPEALSPKARC--LIRDLLRRDPSERLSARDILHHPW</Hsp_qseq>
      <Hsp_hseq>GDLFTLVVAAGKLEYMEADCFFKQLIRGVVYMHEMGVCHRDLKPENLLLTHDGVLKITDFGNSECFKMAWEKNIHLSGGVCGSSPYIAPE----EYIKEEFDPRPVDIWACGVIYMAMRTGRQLWSSAEKDDPFYMNYLKGRKEKGGYEPIESLK-RARCRNVIYSMLDPVPYRRINGKQILNSEW</Hsp_hseq>
      <Hsp_midline>GDL + V A  +L   EA   F Q +  V + H+ G+  RDLK    +   +  +++   G  +   +  + +  L+  V G   Y++PE          +  R  D+W+ GV+   M  G+  +  +E    F       R  +G Y   E+L  +ARC  +I  +L   P  R++ + IL+  W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>1.43123e-06</Hsp_evalue>
      <Hsp_query-from>529</Hsp_query-from>
      <Hsp_query-to>1056</Hsp_query-to>
      <Hsp_hit-from>1263</Hsp_hit-from>
      <Hsp_hit-to>1439</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>183</Hsp_align-len>
      <Hsp_qseq>GDLHSHVRACKRLPEEEAARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLEDVCV-LHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYA--LPEALSPKARCLIRDLLRR----DPSERLSARDILHHPW</Hsp_qseq>
      <Hsp_hseq>GSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMR--GTVFWMAPEMVDTKQGYSAKV----DIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANELLSHPF</Hsp_hseq>
      <Hsp_midline>G + S +R   R  E     L  Q +  + + H  GI+ RD+K    +   +   ++   G+      ++S+ D      G   +++PE++              D+WSLG ++  M  G+ P+   E  A   +I + + A  +PE   P    + R+ L      +P +R +A ++L HP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>2.08973e-06</Hsp_evalue>
      <Hsp_query-from>712</Hsp_query-from>
      <Hsp_query-to>1056</Hsp_query-to>
      <Hsp_hit-from>1441</Hsp_hit-from>
      <Hsp_hit-to>1557</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>119</Hsp_align-len>
      <Hsp_qseq>LEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPT-ALFARIRRG---QYALPEALSPKARCLIRDLLRRDPSERLSARDILHHPW</Hsp_qseq>
      <Hsp_hseq>VSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGAD--DVWSLGCVVLEMITGRRPWANLDNEWAIMYHVAAGHTPQFPTKDEVSSAGMKFLERCLIQNPSKRASAVELLMDPW</Hsp_hseq>
      <Hsp_midline>+ D   + +++++L + +G P Y++PE +T   + G+      DVWSLG ++  M+ G+ P+   +   A+   +  G   Q+   + +S      +   L ++PS+R SA ++L  PW</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>2.1934e-06</Hsp_evalue>
      <Hsp_query-from>628</Hsp_query-from>
      <Hsp_query-to>1059</Hsp_query-to>
      <Hsp_hit-from>478</Hsp_hit-from>
      <Hsp_hit-to>623</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>151</Hsp_align-len>
      <Hsp_qseq>QHGIVLRDLKLRKFV-FRDEDRMRLRLEGLEDVCVLHSDDDSLAE-KVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPTALFARIRRGQYALP-----EALSPKARCLIRDLLRRDPSERLSARDILHHPWF</Hsp_qseq>
      <Hsp_hseq>QHNIIHRDVKPTNILCSANQGTVKLCDFGVSGNLVA-----SLAKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYPPETYDNIFSQLSAIVDGPPPRLPSDKFSSDAQDFVSLCLQKIPERRPTYAALTEHPWL</Hsp_hseq>
      <Hsp_midline>QH I+ RD+K    +   ++  ++L   G+    V      SLA+  +GC +Y++PE + +           +D+WSLG+ +  M +G+YP+       +F+++       P     +  S  A+  +   L++ P  R +   +  HPW </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YDR247W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:956013:957398:1 gene:YDR247W transcript:YDR247W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VHS1 description:Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; VHS1 has a paralog, SKS1, that arose from the whole genome duplication [Source:SGD;Acc:S000002655]</Hit_def>
  <Hit_accession>YDR247W</Hit_accession>
  <Hit_len>461</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.8246</Hsp_bit-score>
      <Hsp_score>107</Hsp_score>
      <Hsp_evalue>9.14317e-06</Hsp_evalue>
      <Hsp_query-from>427</Hsp_query-from>
      <Hsp_query-to>1044</Hsp_query-to>
      <Hsp_hit-from>109</Hsp_hit-from>
      <Hsp_hit-to>327</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>231</Hsp_align-len>
      <Hsp_qseq>LAAYFRIPPHESVACVDEVLLGEHWAYAFLERGCGDLHSHVRACKRLPEEE--AARLFHQAVSAVDHCHQHGIVLRDLKLRKFVFRDEDRMRLRLEGLE--------DVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXX-----------XXDVWSLGVMLYTMLVGQYPFHESEPT--ALFARIRRGQYALPEA--LSPKARCLIRDLLRRDPSERLSARDIL</Hsp_qseq>
      <Hsp_hseq>ISLHLRVHHHKNIVTIHEVLQSAVCTFIVMDYYPTDLFTSIVDNRHFVTNGLLVKKVFLQICSALNYCHEHGIYHCDIKPENLLLDTEDNVFLCDFGLSTTSTYIKPNVC------------IGSSYYMPPERISFDGRVSSSKSGGHKLGKVCPSCNGDLWSLGIILINLTCIRNPWLKADKTEDNTYYYFTKDPNILKQILPLSDDFYSLLSKILQVNPKNRMSLQELM</Hsp_hseq>
      <Hsp_midline>++ + R+  H+++  + EVL      +  ++    DL + +   +          ++F Q  SA+++CH+HGI   D+K    +   ED + L   GL         +VC            +G   Y+ PE ++  G                     D+WSLG++L  +   + P+ +++ T    +    +    L +   LS     L+  +L+ +P  R+S ++++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.2098</Hsp_bit-score>
      <Hsp_score>108</Hsp_score>
      <Hsp_evalue>9.44167e-06</Hsp_evalue>
      <Hsp_query-from>562</Hsp_query-from>
      <Hsp_query-to>1056</Hsp_query-to>
      <Hsp_hit-from>1128</Hsp_hit-from>
      <Hsp_hit-to>1309</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>187</Hsp_align-len>
      <Hsp_qseq>RLPEEEAARLF-HQAVSAVDHCHQHGIVLRDLK----------LRKFVFRDEDRM-------RLRLEGLEDVCVLHSDDDSLAEKVGCPAYVSPEILTXXXXXXXXXXXXXDVWSLGVMLYTMLVGQYPFHESEPT-ALFARIRRGQY-ALP--EALSPKARCLIRDLLRRDPSERLSARDILHHPW</Hsp_qseq>
      <Hsp_hseq>RIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGV---ETKSLNEMMGTPMYMAPE--TISGSAVKGKLGADDVWALGCVVLEMATGRRPWSNLDNEWAIMYHVAAGRIPQLPNRDEMTAAGRAFLERCLVQDPTMRATAVELLIDPW</Hsp_hseq>
      <Hsp_midline>R+ +E   +++  + +  + + HQ G+V RD+K          + K+V     R         +R   ++D  V   +  SL E +G P Y++PE  T  GS+ +    A DVW+LG ++  M  G+ P+   +   A+   +  G+   LP  + ++   R  +   L +DP+ R +A ++L  PW</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>93</Statistics_hsp-len>
      <Statistics_eff-space>841897722</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056652-RA transcript Note:&quot;Similar to SMC6 Structural maintenance of chromosomes protein 6 (Homo sapiens)&quot; offset:253 AED:0.22 eAED:0.22 QI:253|0.38|0.64|1|0.92|0.85|14|2806|530</Iteration_query-def>
  <Iteration_query-len>4652</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3232984349</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056654-RA transcript Note:&quot;Similar to fkbp1a Peptidyl-prolyl cis-trans isomerase FKBP1A (Xenopus laevis)&quot; offset:231 AED:0.08 eAED:0.08 QI:231|1|1|1|0.75|0.6|5|3226|108</Iteration_query-def>
  <Iteration_query-len>3784</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YNL135C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:371882:372226:-1 gene:YNL135C transcript:YNL135C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPR1 description:Peptidyl-prolyl cis-trans isomerase (PPIase); binds to the drugs FK506 and rapamycin; also binds to the nonhistone chromatin binding protein Hmo1p and may regulate its assembly or function; N-terminally propionylated in vivo; mutation is functionally complemented by human FKBP1A [Source:SGD;Acc:S000005079]</Hit_def>
  <Hit_accession>YNL135C</Hit_accession>
  <Hit_len>114</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>135.191</Hsp_bit-score>
      <Hsp_score>339</Hsp_score>
      <Hsp_evalue>1.43858e-37</Hsp_evalue>
      <Hsp_query-from>238</Hsp_query-from>
      <Hsp_query-to>555</Hsp_query-to>
      <Hsp_hit-from>9</Hsp_hit-from>
      <Hsp_hit-to>114</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>83</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>106</Hsp_align-len>
      <Hsp_qseq>VQVETITPGDGQTFPKKGQTVVVHYTGTLEDGKKFDSSRDRDKPFKFKIGKQEVIRGWEEGVAQMSVGQRARLTCSPDFAYGAIGHPGVIPPNATLLFDVELLRLE</Hsp_qseq>
      <Hsp_hseq>VKIDRISPGDGATFPKTGDLVTIHYTGTLENGQKFDSSVDRGSPFQCNIGVGQVIKGWDVGIPKLSVGEKARLTIPGPYAYGPRGFPGLIPPNSTLVFDVELLKVN</Hsp_hseq>
      <Hsp_midline>V+++ I+PGDG TFPK G  V +HYTGTLE+G+KFDSS DR  PF+  IG  +VI+GW+ G+ ++SVG++ARLT    +AYG  G PG+IPPN+TL+FDVELL++ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YDR519W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1480425:1480832:1 gene:YDR519W transcript:YDR519W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPR2 description:Membrane-bound peptidyl-prolyl cis-trans isomerase (PPIase); binds to the drugs FK506 and rapamycin; expression pattern suggests possible involvement in ER protein trafficking; relocalizes from nucleus to vacuole upon DNA replication stress; mutation is functionally complemented by human FKBP2 [Source:SGD;Acc:S000002927]</Hit_def>
  <Hit_accession>YDR519W</Hit_accession>
  <Hit_len>135</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.5077</Hsp_bit-score>
      <Hsp_score>223</Hsp_score>
      <Hsp_evalue>9.54175e-22</Hsp_evalue>
      <Hsp_query-from>289</Hsp_query-from>
      <Hsp_query-to>555</Hsp_query-to>
      <Hsp_hit-from>43</Hsp_hit-from>
      <Hsp_hit-to>132</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>90</Hsp_align-len>
      <Hsp_qseq>GQTVVVHYTGTL-EDGKKFDSSRDRDKPFKFKIGKQEVIRGWEEGVAQMSVGQRARLTCSPDFAYGAIGHPGVIPPNATLLFDVELLRLE</Hsp_qseq>
      <Hsp_hseq>GDKVKVHYTGSLLESGTVFDSSYSRGSPIAFELGVGRVIKGWDQGVAGMCVGEKRKLQIPSSLAYGERGVPGVIPPSADLVFDVELVDVK</Hsp_hseq>
      <Hsp_midline>G  V VHYTG+L E G  FDSS  R  P  F++G   VI+GW++GVA M VG++ +L      AYG  G PGVIPP+A L+FDVEL+ ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YML074C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:120089:121324:-1 gene:YML074C transcript:YML074C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPR3 description:Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase); FK506 binding protein; affects expression of multiple genes via its role in nucleosome assembly; phosphorylated by casein kinase II (Cka1p-Cka2p-Ckb1p-Ckb2p) and dephosphorylated by Ptp1p; PPIase domain acts as a transcriptional repressor when tethered to DNA by lexA, and repressor activity is dependent on PPIase activity; FPR3 has a paralog, FPR4, that arose from the whole genome duplication [Source:SGD;Acc:S000004539]</Hit_def>
  <Hit_accession>YML074C</Hit_accession>
  <Hit_len>411</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>84.3445</Hsp_bit-score>
      <Hsp_score>207</Hsp_score>
      <Hsp_evalue>1.97445e-17</Hsp_evalue>
      <Hsp_query-from>202</Hsp_query-from>
      <Hsp_query-to>555</Hsp_query-to>
      <Hsp_hit-from>296</Hsp_hit-from>
      <Hsp_hit-to>410</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>118</Hsp_align-len>
      <Hsp_qseq>RQRPRRTATTMGVQVETITPGDGQTFPKKGQTVVVHYTGTLEDGKKFDSSRDRDKPFKFKIGKQEVIRGWEEGVAQMSVGQRARLTCSPDFAYGAIGHPGVIPPNATLLFDVELLRLE</Hsp_qseq>
      <Hsp_hseq>KHKPKSKVLEGGIVIEDRTIGDGPQ-AKRGARVGMRYIGKLKNGKVFDKNT-SGKPFAFKLGRGEVIKGWDIGVAGMSVGGERRIIIPAPYAYGKQALPG-IPANSELTFDVKLVSMK</Hsp_hseq>
      <Hsp_midline>+ +P+      G+ +E  T GDG    K+G  V + Y G L++GK FD +    KPF FK+G+ EVI+GW+ GVA MSVG   R+     +AYG    PG IP N+ L FDV+L+ ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YLR449W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:1030834:1032012:1 gene:YLR449W transcript:YLR449W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPR4 description:Peptidyl-prolyl cis-trans isomerase (PPIase); nuclear proline isomerase; affects expression of multiple genes via its role in nucleosome assembly; catalyzes isomerization of proline residues in histones H3 and H4, which affects lysine methylation of those histones; PPIase domain acts as a transcriptional repressor when tethered to DNA by lexA, and repressor activity is dependent on PPIase activity; contains a nucleoplasmin-like fold and can form pentamers [Source:SGD;Acc:S000004441]</Hit_def>
  <Hit_accession>YLR449W</Hit_accession>
  <Hit_len>392</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.337</Hsp_bit-score>
      <Hsp_score>194</Hsp_score>
      <Hsp_evalue>7.10148e-16</Hsp_evalue>
      <Hsp_query-from>208</Hsp_query-from>
      <Hsp_query-to>555</Hsp_query-to>
      <Hsp_hit-from>280</Hsp_hit-from>
      <Hsp_hit-to>392</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>116</Hsp_align-len>
      <Hsp_qseq>RPRRTATTMGVQVETITPGDGQTFPKKGQTVVVHYTGTLEDGKKFDSSRDRDKPFKFKIGKQEVIRGWEEGVAQMSVGQRARLTCSPDFAYGAIGHPGVIPPNATLLFDVELLRLE</Hsp_qseq>
      <Hsp_hseq>KPKTKLLEGGIIIEDRVTGKG-PHAKKGTRVGMRYVGKLKNGKVFDKNT-KGKPFVFKLGQGEVIKGWDIGVAGMAVGGERRIVIPAPYAYGKQALPG-IPANSELTFDVKLVSMK</Hsp_hseq>
      <Hsp_midline>+P+      G+ +E    G G    KKG  V + Y G L++GK FD +  + KPF FK+G+ EVI+GW+ GVA M+VG   R+     +AYG    PG IP N+ L FDV+L+ ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2607061720</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0041080-RA transcript Note:&quot;Similar to Ptprm Receptor-type tyrosine-protein phosphatase mu (Mus musculus)&quot; offset:0 AED:0.24 eAED:0.43 QI:0|0|0|0.5|0|0.5|2|0|127</Iteration_query-def>
  <Iteration_query-len>384</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>79</Statistics_hsp-len>
      <Statistics_eff-space>117240683</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056658-RA transcript Note:&quot;Similar to Ptprm Receptor-type tyrosine-protein phosphatase mu (Mus musculus)&quot; offset:0 AED:0.52 eAED:0.52 QI:0|0|0|0.25|0.95|0.95|24|0|1186</Iteration_query-def>
  <Iteration_query-len>3561</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDL230W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:42700:43707:1 gene:YDL230W transcript:YDL230W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTP1 description:Phosphotyrosine-specific protein phosphatase; dephosphorylates a broad range of substrates in vivo, including Fpr3p; localized to the cytoplasm and the mitochondria; proposed to be a negative regulator of filamentation [Source:SGD;Acc:S000002389]</Hit_def>
  <Hit_accession>YDL230W</Hit_accession>
  <Hit_len>335</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>104.375</Hsp_bit-score>
      <Hsp_score>259</Hsp_score>
      <Hsp_evalue>1.85282e-24</Hsp_evalue>
      <Hsp_query-from>1975</Hsp_query-from>
      <Hsp_query-to>2718</Hsp_query-to>
      <Hsp_hit-from>11</Hsp_hit-from>
      <Hsp_hit-to>322</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>90</Hsp_identity>
      <Hsp_positive>137</Hsp_positive>
      <Hsp_gaps>88</Hsp_gaps>
      <Hsp_align-len>324</Hsp_align-len>
      <Hsp_qseq>RVADLLQHIGQMKSTEGCGFKEEYESFLDGQSAPWQ--VAKKDENRGRNRYGNIIAYDHSRVVLEPLEGKPESDYINGNYVD----------GYQKQRQYIATQGPLQETAVDFWRMVWQE---KSSSIVMV---------KCFKYWP---------------------DDTQLLGDIAVTLLHTELLAEYVIRT--------------FSVKRFHFTGWPDHGVPAFATGLLSFVRRVKASNPPEAGPIITHCSAGAGRTGCYVVIDVML----------------EMAGREGVID-VYNCVRELRLQRVNMVQTEEQYVFIH</Hsp_qseq>
      <Hsp_hseq>RDTDLLGKFKFIQNQEDGRLREATNGTVNSR---WSLGVSIEPRNDARNRYVNIMPYERNRVHLKTLSG---NDYINASYVKVNVPGQSIEPGY-----YIATQGPTRKTWDQFWQMCYHNCPLDNIVIVMVTPLVEYNREKCYQYWPRGGVDDTVRIASKWESPGGANDMTQFPSDLKIEFVNVHKVKDYYTVTDIKLTPTDPLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNS-RGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITERSRHSDRATEEYTRDLIEQIVLQLRSQRMKMVQTKDQFLFIY</Hsp_hseq>
      <Hsp_midline>R  DLL     +++ E    +E     ++ +   W   V+ +  N  RNRY NI+ Y+ +RV L+ L G   +DYIN +YV           GY     YIATQGP ++T   FW+M +      +  IVMV         KC++YWP                     D TQ   D+ +  ++   + +Y   T               +V  F+F  W D   P     ++       + N     PII HCSAG GRTG ++ +D ++                + A  E   D +   V +LR QR+ MVQT++Q++FI+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YOR208W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:733925:736177:1 gene:YOR208W transcript:YOR208W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTP2 description:Nuclear phosphotyrosine-specific phosphatase involved in osmosensing; involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; with Msg5p co-regulates the calcium signaling pathway [Source:SGD;Acc:S000005734]</Hit_def>
  <Hit_accession>YOR208W</Hit_accession>
  <Hit_len>750</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>1.39543e-09</Hsp_evalue>
      <Hsp_query-from>2533</Hsp_query-from>
      <Hsp_query-to>2733</Hsp_query-to>
      <Hsp_hit-from>658</Hsp_hit-from>
      <Hsp_hit-to>736</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>43</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>79</Hsp_align-len>
      <Hsp_qseq>EAGPIITHCSAGAGRTGCYVVIDVMLEM----AGREGVIDVYN--------CVRELRLQRVNMVQTEEQYVFIHDVLLE</Hsp_qseq>
      <Hsp_hseq>NSSPLLVHCSAGCGRTGVFVTLDFLLSILSPTTNHSNKIDVWNMTQDLIFIIVNELRKQRISMVQNLTQYIACYEALLN</Hsp_hseq>
      <Hsp_midline> + P++ HCSAG GRTG +V +D +L +          IDV+N         V ELR QR++MVQ   QY+  ++ LL </Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>6.5812e-07</Hsp_evalue>
      <Hsp_query-from>2110</Hsp_query-from>
      <Hsp_query-to>2319</Hsp_query-to>
      <Hsp_hit-from>411</Hsp_hit-from>
      <Hsp_hit-to>511</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>101</Hsp_align-len>
      <Hsp_qseq>RNRYGNIIAYDHSRVVLE-------------------------PLEGKPES----DYINGNYVDGYQ--KQRQYIATQGPLQETAVDFWRMVWQEKSSSIV</Hsp_qseq>
      <Hsp_hseq>KNRYSNILPYEHSRVKLPHSPKPPAVSEASTTETKTDKSYPMCPVDAKNHSCKPNDYINANYLKLTQINPDFKYIATQAPLPSTMDDFWKVITLNKVKVII</Hsp_hseq>
      <Hsp_midline>+NRY NI+ Y+HSRV L                          P++ K  S    DYIN NY+   Q     +YIATQ PL  T  DFW+++   K   I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YER075C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:308413:311199:-1 gene:YER075C transcript:YER075C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTP3 description:Phosphotyrosine-specific protein phosphatase; involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the cytoplasm [Source:SGD;Acc:S000000877]</Hit_def>
  <Hit_accession>YER075C</Hit_accession>
  <Hit_len>928</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>2.91455e-07</Hsp_evalue>
      <Hsp_query-from>2296</Hsp_query-from>
      <Hsp_query-to>2730</Hsp_query-to>
      <Hsp_hit-from>746</Hsp_hit-from>
      <Hsp_hit-to>876</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>QEKSSSIVMVKCFKYWPDDTQLLGDIAVTLLHTELLAEYVIRTFSVKRFHFTGWPDHGVPAFATGLLSFVRRVKASNPPEAGPIITHCSAGAGRTGCYVVIDV------MLEMAGREGVIDVYNC---------VRELRLQRVNMVQTEEQYVFIHDVLL</Hsp_qseq>
      <Hsp_hseq>QEKPYELLQIQV-KNWPDLGTLLNPISI--LQAINVKNHIIDTLFARNY----YQNDQLPT----------------------ILVHCSAGCGRTGTLCTIDSILSNFEMFEMLQKEFVKLKYPAKLFDPISWTINIFRKQRISMVQNINQFIFIYDCLL</Hsp_hseq>
      <Hsp_midline>QEK   ++ ++  K WPD   LL  I++  L    +  ++I T   + +    + +  +P                       I+ HCSAG GRTG    ID       M EM  +E V   Y           +   R QR++MVQ   Q++FI+D LL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2440749162</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056660-RA transcript Note:&quot;Similar to L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 (Homo sapiens)&quot; offset:22 AED:0.08 eAED:0.08 QI:22|0.55|0.78|0.94|0.61|0.63|19|2822|696</Iteration_query-def>
  <Iteration_query-len>4935</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3445239714</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0020175-RA transcript Note:&quot;Similar to tmem200a Transmembrane protein 200A (Danio rerio)&quot; offset:0 AED:0.33 eAED:0.45 QI:0|-1|0|1|-1|1|1|0|529</Iteration_query-def>
  <Iteration_query-len>1590</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>1000038812</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056661-RA transcript Note:&quot;Similar to PPP1R8 Nuclear inhibitor of protein phosphatase 1 (Bos taurus)&quot; offset:40 AED:0.24 eAED:0.24 QI:40|1|1|1|1|1|7|1389|370</Iteration_query-def>
  <Iteration_query-len>2542</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1698182983</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056662-RA transcript Note:&quot;Similar to TRNAU1AP tRNA selenocysteine 1-associated protein 1 (Homo sapiens)&quot; offset:103 AED:0.20 eAED:0.20 QI:103|0.85|0.87|1|0.42|0.37|8|1491|142</Iteration_query-def>
  <Iteration_query-len>2023</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YHR086W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:278153:279724:1 gene:YHR086W transcript:YHR086W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NAM8 description:RNA binding protein, component of the U1 snRNP protein; mutants are defective in meiotic recombination and in formation of viable spores, involved in the formation of DSBs through meiosis-specific splicing of REC107 pre-mRNA; Nam8p regulon embraces the meiotic pre-mRNAs of REC107, HFM1, AMA1 SPO22 and PCH2; the putative RNA binding domains RRM2 and RRM3 are required for Nam8p meiotic function [Source:SGD;Acc:S000001128]</Hit_def>
  <Hit_accession>YHR086W</Hit_accession>
  <Hit_len>523</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.5514</Hsp_bit-score>
      <Hsp_score>166</Hsp_score>
      <Hsp_evalue>1.23378e-12</Hsp_evalue>
      <Hsp_query-from>113</Hsp_query-from>
      <Hsp_query-to>502</Hsp_query-to>
      <Hsp_hit-from>56</Hsp_hit-from>
      <Hsp_hit-to>237</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>56</Hsp_gaps>
      <Hsp_align-len>184</Hsp_align-len>
      <Hsp_qseq>LWIGDLDPAMDQSFVARAFASVGENVTGVKIIRN-------RLTGAPA---GYGFVEFLDQSTAERCLHSLNGQPIPG-------------------------------------------AAHLYDFFVRRYPSCRAGKVVVDDL-GHSRGFGFVRFRDEREQKAALVEMQSAVGLGGRPLRI</Hsp_qseq>
      <Hsp_hseq>LYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPSSTHAANALLK-NGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQ-GVFLNGRAIKV</Hsp_hseq>
      <Hsp_midline>L++GDLDP  D++ V + +AS+GE    V+++ N       R +  P    GY FV+F   + A   L   NG  IP                                             + L++ F+ RY S    K+V D + G S+G+GFV+F +  EQ+ AL EMQ  V L GR +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YER165W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:510373:512106:1 gene:YER165W transcript:YER165W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PAB1 description:Poly(A) binding protein; part of the 3&apos;-end RNA-processing complex, mediates interactions between the 5&apos; cap structure and the 3&apos; mRNA poly(A) tail, involved in control of poly(A) tail length, interacts with translation factor eIF-4G; stimulates, but is not required for the deadenylation activity of the Pan2p-Pan3p poly(A)-ribonuclease complex [Source:SGD;Acc:S000000967]</Hit_def>
  <Hit_accession>YER165W</Hit_accession>
  <Hit_len>577</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>5.04113e-11</Hsp_evalue>
      <Hsp_query-from>80</Hsp_query-from>
      <Hsp_query-to>454</Hsp_query-to>
      <Hsp_hit-from>29</Hsp_hit-from>
      <Hsp_hit-to>183</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>157</Hsp_align-len>
      <Hsp_qseq>DTETTKAAMSSLWIGDLDPAMDQSFVARAFASVGENVTGVKIIRNRLTGAPAGYGFVEFLDQSTAERCLHSLNGQPIPG--------------------------------AAHLYDFFVRRYPSCRAGKVVVDDLGHSRGFGFVRFRDEREQKAAL</Hsp_qseq>
      <Hsp_hseq>ESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIG-SVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTF-SVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAI</Hsp_hseq>
      <Hsp_midline>++++ + + +SL++GDL+P++ ++ +   F+ +G +V+ +++ R+ +T    GY +V F D     + +  LN  PI G                                   LYD F   +    + K+  D+ G S+GFGFV F +E   K A+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YBR212W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:647886:649904:1 gene:YBR212W transcript:YBR212W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NGR1 description:RNA binding protein that negatively regulates growth rate; interacts with the 3&apos; UTR of the mitochondrial porin (POR1) mRNA and enhances its degradation; overexpression impairs mitochondrial function; interacts with Dhh1p to mediate POR1 mRNA decay; expressed in stationary phase [Source:SGD;Acc:S000000416]</Hit_def>
  <Hit_accession>YBR212W</Hit_accession>
  <Hit_len>672</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>5.59037e-09</Hsp_evalue>
      <Hsp_query-from>86</Hsp_query-from>
      <Hsp_query-to>523</Hsp_query-to>
      <Hsp_hit-from>27</Hsp_hit-from>
      <Hsp_hit-to>273</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>84</Hsp_positive>
      <Hsp_gaps>105</Hsp_gaps>
      <Hsp_align-len>249</Hsp_align-len>
      <Hsp_qseq>ETTKAAMSSLWIGDLDPAMDQSFVARAFASVGE---------------------------------------------------NVTGVKIIRNRLTGAP-AGYGFVEFLDQSTAERCLHSLNGQPIPG--------------------------------------------------AAHLYDFFVRRYPSCRAGKVVVDDL-GHSRGFGFVRFRDEREQKAALVEMQSAVGLGGRPLRINLANPKR</Hsp_qseq>
      <Hsp_hseq>ETSTEPPRTLWMGDLDPSFDEATIEEIWSKLDKKVIVKLIRAKKNLLIPCSSTSSSNNNTSEENAENQQSASNSTDQLDNSQMININGISFIDPSTTQLHHAGYCFVEFETQKDAKFAL-SLNATPLPNFYSPTTNSQTNPTFKRTFRLNWASGATLQSSIPSTPEFSLFVGDLSPTATEADLLSLFQTRFKSVKTVRVMTDPLTGSSRCFGFVRFGDEDERRRALIEM-SGKWFQGRALRVAYATPRN</Hsp_hseq>
      <Hsp_midline>ET+     +LW+GDLDP+ D++ +   ++ + +                                                   N+ G+  I    T    AGY FVEF  Q  A+  L SLN  P+P                                                    A L   F  R+ S +  +V+ D L G SR FGFVRF DE E++ AL+EM S     GR LR+  A P+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YGR159C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:806412:807656:-1 gene:YGR159C transcript:YGR159C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NSR1 description:Nucleolar protein that binds nuclear localization sequences; required for pre-rRNA processing and ribosome biogenesis; binds to single stranded telomeric DNA and mRNA; methylated by Hmt1p; interaction with Top1p and nucleolar localization are negatively regulated by polyphosphorylation [Source:SGD;Acc:S000003391]</Hit_def>
  <Hit_accession>YGR159C</Hit_accession>
  <Hit_len>414</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>4.70035e-07</Hsp_evalue>
      <Hsp_query-from>107</Hsp_query-from>
      <Hsp_query-to>529</Hsp_query-to>
      <Hsp_hit-from>168</Hsp_hit-from>
      <Hsp_hit-to>349</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>184</Hsp_align-len>
      <Hsp_qseq>SSLWIGDLDPAMDQSFVARAFASVGENVTGVKIIRNRLTGAPAGYGFVEFLDQSTAERCLHSLNGQPIPGAAHLYDFFVRR-------------YPS------------------------CRAGKVVV------DDLGHSRGFGFVRFRDEREQKAALVEMQSAVGLGGRPLRINLANPKRIN</Hsp_qseq>
      <Hsp_hseq>ATIFVGRLSWSIDDEWLKKEFEHIG-GVIGARVIYERGTDRSRGYGYVDFENKSYAEKAIQEMQGKEIDGRPINCDMSTSKPAGNNDRAKKFGDTPSEPSDTLFLGNLSFNADRDAIFELFAKHGEVVSVRIPTHPETEQPKGFGYVQFSNMEDAKKALDALQGEY-IDNRPVRLDFSSPRPNN</Hsp_hseq>
      <Hsp_midline>+++++G L  ++D  ++ + F  +G  V G ++I  R T    GYG+V+F ++S AE+ +  + G+ I G     D    +              PS                         + G+VV        +    +GFG+V+F +  + K AL  +Q    +  RP+R++ ++P+  N</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1318109926</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056663-RA transcript Note:&quot;Similar to Stx12 Syntaxin-12 (Rattus norvegicus)&quot; offset:45 AED:0.26 eAED:0.26 QI:45|0.62|0.55|1|1|1|9|2966|297</Iteration_query-def>
  <Iteration_query-len>3905</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YOR036W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:400348:401214:1 gene:YOR036W transcript:YOR036W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PEP12 description:Target membrane receptor (t-SNARE); for vesicular intermediates traveling between the Golgi apparatus and the vacuole; controls entry of biosynthetic, endocytic, and retrograde traffic into the prevacuolar compartment; syntaxin [Source:SGD;Acc:S000005562]</Hit_def>
  <Hit_accession>YOR036W</Hit_accession>
  <Hit_len>288</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.9954</Hsp_bit-score>
      <Hsp_score>136</Hsp_score>
      <Hsp_evalue>5.81519e-09</Hsp_evalue>
      <Hsp_query-from>655</Hsp_query-from>
      <Hsp_query-to>846</Hsp_query-to>
      <Hsp_hit-from>198</Hsp_hit-from>
      <Hsp_hit-to>261</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>25</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>64</Hsp_align-len>
      <Hsp_qseq>IKEREVAIQMLEADIMDINQIFKDLGTMIHEQGDMIDSIEANVETAEVHVEQANQQLRRAAQYQ</Hsp_qseq>
      <Hsp_hseq>IEQRDQEISNIERGITELNEVFKDLGSVVQQQGVLVDNIEANIYTTSDNTQLASDELRKAMRYQ</Hsp_hseq>
      <Hsp_midline>I++R+  I  +E  I ++N++FKDLG+++ +QG ++D+IEAN+ T   + + A+ +LR+A +YQ</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2696960400</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056664-RA transcript Note:&quot;Similar to moxd1 DBH-like monooxygenase protein 1 homolog (Danio rerio)&quot; offset:0 AED:0.18 eAED:0.18 QI:0|0.44|0.7|0.9|1|1|10|901|546</Iteration_query-def>
  <Iteration_query-len>2542</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1698182983</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056636-RA transcript Note:&quot;Similar to SNTG2 Gamma-2-syntrophin (Homo sapiens)&quot; offset:0 AED:0.14 eAED:0.22 QI:0|0|0|0.85|0.33|0.57|7|0|195</Iteration_query-def>
  <Iteration_query-len>588</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>85</Statistics_hsp-len>
      <Statistics_eff-space>261190437</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056637-RA transcript Note:&quot;Similar to PXDN Peroxidasin homolog (Homo sapiens)&quot; offset:0 AED:0.22 eAED:0.22 QI:0|0.56|0.47|1|0.68|0.70|17|2337|1160</Iteration_query-def>
  <Iteration_query-len>5820</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>104</Statistics_hsp-len>
      <Statistics_eff-space>4089996612</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056638-RA transcript Note:&quot;Similar to GGT7 Glutathione hydrolase 7 (Homo sapiens)&quot; offset:484 AED:0.03 eAED:0.03 QI:484|0.92|0.93|1|0.42|0.4|15|1825|599</Iteration_query-def>
  <Iteration_query-len>4109</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YLR299W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:726069:728051:1 gene:YLR299W transcript:YLR299W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ECM38 description:Gamma-glutamyltranspeptidase; major glutathione-degrading enzyme; involved in detoxification of electrophilic xenobiotics; expression induced mainly by nitrogen starvation [Source:SGD;Acc:S000004290]</Hit_def>
  <Hit_accession>YLR299W</Hit_accession>
  <Hit_len>660</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.9669</Hsp_bit-score>
      <Hsp_score>219</Hsp_score>
      <Hsp_evalue>2.27693e-18</Hsp_evalue>
      <Hsp_query-from>881</Hsp_query-from>
      <Hsp_query-to>2116</Hsp_query-to>
      <Hsp_hit-from>103</Hsp_hit-from>
      <Hsp_hit-to>547</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>134</Hsp_identity>
      <Hsp_positive>220</Hsp_positive>
      <Hsp_gaps>75</Hsp_gaps>
      <Hsp_align-len>466</Hsp_align-len>
      <Hsp_qseq>QVYYNGTVVSDVRLCSDIGTD--ILHKRGSSV-DAAVATALCAGIVHPXXXXXXXXXXXXXXNIKENTTRAIDFWAVAPAEDXXXXXXXXXXTA---GLSVGVPGMIKGLYQAHQLY--GRMPWGEVVAAAARVAKDGFNV------TTELASAVGHLLSGNLSASLRGVFAPGGQGVLA-GDPMKRLDLANVLDAIALHGPDAVY---QSNLTLELIAQVAANGGVLSAEDFSNYSVLVQNPLETTYQG---------HLLLSAPPPHAGASLLLALGIMEGYNLSTHDDGNL----TYHWLTEALKFSFIQGSTLGD-----------PTVDASVAER-MQNILSKLEAGRIRELINDTWTLPADSYGARQ--------LIDSYGDASSVLVMGPDDLIVAMTSSLSGAFGSRVMTP-SGILLNSAMLDFT--DPSQSPNPTAGQANVMGPGRRPITWALPTIA</Hsp_qseq>
      <Hsp_hseq>KVGLHGAISSDLEVCSNLTINEVLLKFPGSNAADAAVTQALCKGMVNFFNSGIGGGGYVVFSGKDDEDHLSIDFREKAPMDSHKFMFENCSLCSKIGGLAVGVPGELMGLYRLFKERGSGQVDWRDLIEPVAKLGSVGWQIGEALGATLELYEDVFLTLKEDWSFVLNSTH----DGVLKEGDWIKRPALSNMLMELAKNGSVAPFYDPDHWIAKSMIDTVAKYNGIMNLQDVSSYDVHVTKPLSMKIRKGANFIPDNDMTVLTSSGSSSGAALLAALRIMD--NFQNQEGGDYEKETTYH-LLESMKWMASARSRLGDFEGEALPKHIEEVLDPEWALKAVKSIKRNSQDGNFKTLEN--WTLYDPAYDINNPHGTAHFSIVDSHGNA------------VSLTTTINLLFGSLVHDPKTGVIFNNEMDDFAQFNKSNSFELAPSIYNFPEPGKRPLSSTAPTIV</Hsp_hseq>
      <Hsp_midline>+V  +G + SD+ +CS++  +  +L   GS+  DAAV  ALC G+V+  +SG+GGGG ++     +    +IDF   AP +   F   N +L +   GL+VGVPG + GLY+  +    G++ W +++   A++   G+ +      T EL   V   L  + S  L         GVL  GD +KR  L+N+L  +A +G  A +      +   +I  VA   G+++ +D S+Y V V  PL    +            +L++    +GA+LL AL IM+  N    + G+     TYH L E++K+     S LGD             +D   A + +++I    + G  + L N  WTL   +Y            ++DS+G+A            V++T++++  FGS V  P +G++ N+ M DF   + S S        N   PG+RP++   PTI </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>102</Statistics_hsp-len>
      <Statistics_eff-space>2839178489</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0041084-RA transcript Note:&quot;Protein of unknown function&quot; offset:144 AED:1.00 eAED:1.00 QI:144|0|0|0|0.2|0.33|6|0|191</Iteration_query-def>
  <Iteration_query-len>720</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>87</Statistics_hsp-len>
      <Statistics_eff-space>357999651</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0056641-RA transcript Note:&quot;Similar to TUBE1 Tubulin epsilon chain (Homo sapiens)&quot; offset:146 AED:0.25 eAED:0.25 QI:146|0.88|0.9|1|0.55|0.6|10|916|431</Iteration_query-def>
  <Iteration_query-len>2358</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YML085C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:97941:99400:-1 gene:YML085C transcript:YML085C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TUB1 description:Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules; relative distribution to nuclear foci increases upon DNA replication stress; TUB1 has a paralog, TUB3, that arose from the whole genome duplication [Source:SGD;Acc:S000004550]</Hit_def>
  <Hit_accession>YML085C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>223.016</Hsp_bit-score>
      <Hsp_score>567</Hsp_score>
      <Hsp_evalue>2.48685e-65</Hsp_evalue>
      <Hsp_query-from>234</Hsp_query-from>
      <Hsp_query-to>1376</Hsp_query-to>
      <Hsp_hit-from>65</Hsp_hit-from>
      <Hsp_hit-to>433</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>136</Hsp_identity>
      <Hsp_positive>217</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>395</Hsp_align-len>
      <Hsp_qseq>RAVLIDMEEGVVNELLQGPLRDVFDQKQLITDVSGSGNNWAVGNKVYGAQFREKILERLRVTAEHCDSLQCFFLIHSMXXXXXXXXXXFVLRLLEDEFPDVHRFVMALYPSAE-DDVVTSPYNSVLAMRELTEHADCVLPIENQALVDIVNKINHAAALGKSVRSQTTLSSSHGCLKGQEKP---FDTMNNIVANLMLNMTSSSRFEGSLNVDLNEITMNLVPFPRLHYLVSSLTPLYALADVALPPRRLDQMFSDAFSKENQLLRVDPRRSLYLACALMVRGNVQLSDVRRNIERL--KPSLHFVDWNEEGWKTGLCSVPPVGYPHSLLA--------LANNTCVKHTFADIQERFARLYRRKAHLHHYTDVEGMELSCFTEAASSLASVIEEY</Hsp_qseq>
      <Hsp_hseq>RAIYVDLEPNVIDEVRNGPYKDLFHPEQLISGKEDAANNYARGHYTVGREILGDVLDRIRKLADQCDGLQGFLFTHSLGGGTGSGLGSLLLEELSAEYGKKSKLEFAVYPAPQVSTSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDM-------------------------CKRNLDIPRPSFANLNNLIAQVVSSVTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYSPVLSKSKAFHESNSVSEITNACFEPGNQMVKCDPRDGKYMATCLLYRGDVVTRDVQRAVEQVKNKKTVQLVDWCPTGFKIGICYEPPTATPNSQLATVDRAVCMLSNTTSIAEAWKRIDRKFDLMYAKRAFVHWYVG-EGMEEGEFTEAREDLAALERDY</Hsp_hseq>
      <Hsp_midline>RA+ +D+E  V++E+  GP +D+F  +QLI+    + NN+A G+   G +    +L+R+R  A+ CD LQ F   HS+GGGTGSGLG+ +L  L  E+    +   A+YP+ +    V  PYN+VL      EHADC   ++N+A+ D+                         C +  + P   F  +NN++A ++ ++T+S RF+GSLNVDLNE   NLVP+PR+H+ + S +P+ + +        + ++ +  F   NQ+++ DPR   Y+A  L+ RG+V   DV+R +E++  K ++  VDW   G+K G+C  PP   P+S LA        L+N T +   +  I  +F  +Y ++A +H Y   EGME   FTEA   LA++  +Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YML124C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:22048:23683:-1 gene:YML124C transcript:YML124C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TUB3 description:Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules; expressed at lower level than Tub1p; TUB3 has a paralog, TUB1, that arose from the whole genome duplication [Source:SGD;Acc:S000004593]</Hit_def>
  <Hit_accession>YML124C</Hit_accession>
  <Hit_len>445</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>215.698</Hsp_bit-score>
      <Hsp_score>548</Hsp_score>
      <Hsp_evalue>1.03945e-62</Hsp_evalue>
      <Hsp_query-from>234</Hsp_query-from>
      <Hsp_query-to>1376</Hsp_query-to>
      <Hsp_hit-from>65</Hsp_hit-from>
      <Hsp_hit-to>433</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>135</Hsp_identity>
      <Hsp_positive>214</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>392</Hsp_align-len>
      <Hsp_qseq>RAVLIDMEEGVVNELLQGPLRDVFDQKQLITDVSGSGNNWAVGNKVYGAQFREKILERLRVTAEHCDSLQCFFLIHSMXXXXXXXXXXFVLRLLEDEFPDVHRFVMALYPSAE-DDVVTSPYNSVLAMRELTEHADCVLPIENQALVDIVNKINHAAALGKSVRSQTTLSSSHGCLKGQEKPFDTMNNIVANLMLNMTSSSRFEGSLNVDLNEITMNLVPFPRLHYLVSSLTPLYALADVALPPRRLDQMFSDAFSKENQLLRVDPRRSLYLACALMVRGNVQLSDVRRNIERL--KPSLHFVDWNEEGWKTGLCSVPPVGYPHSLLA--------LANNTCVKHTFADIQERFARLYRRKAHLHHYTDVEGMELSCFTEAASSLASVIEEY</Hsp_qseq>
      <Hsp_hseq>RAIYVDLEPNVIDEVRTGRFKELFHPEQLINGKEDAANNYARGHYTVGREIVDEVEERIRKMADQCDGLQGFLFTHSLGGGTGSGLGSLLLENLSYEYGKKSKLEFAVYPAPQLSTSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDICKR-----NLGISRPS-----------------FSNLNGLIAQVISSVTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYAPILSKKRATHESNSVSEITNACFEPGNQMVKCDPTKGKYMANCLLYRGDVVTRDVQRAVEQVKNKKTVQMVDWCPTGFKIGICYEPPSVIPSSELANVDRAVCMLSNTTAIADAWKRIDQKFDLMYAKRAFVHWYVG-EGMEEGEFTEAREDLAALERDY</Hsp_hseq>
      <Hsp_midline>RA+ +D+E  V++E+  G  +++F  +QLI     + NN+A G+   G +  +++ ER+R  A+ CD LQ F   HS+GGGTGSGLG+ +L  L  E+    +   A+YP+ +    V  PYN+VL      EHADC   ++N+A+ DI  +      LG S  S                 F  +N ++A ++ ++T+S RF+GSLNVDLNE   NLVP+PR+H+ + S  P+ +          + ++ +  F   NQ+++ DP +  Y+A  L+ RG+V   DV+R +E++  K ++  VDW   G+K G+C  PP   P S LA        L+N T +   +  I ++F  +Y ++A +H Y   EGME   FTEA   LA++  +Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YFL037W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:56336:57709:1 gene:YFL037W transcript:YFL037W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TUB2 description:Beta-tubulin; associates with alpha-tubulin (Tub1p and Tub3p) to form tubulin dimer, which polymerizes to form microtubules; mutation in human ortholog is associated with congenital fibrosis of the extraocular muscles (CFEOM) with polymicrogyria [Source:SGD;Acc:S000001857]</Hit_def>
  <Hit_accession>YFL037W</Hit_accession>
  <Hit_len>457</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>213.001</Hsp_bit-score>
      <Hsp_score>541</Hsp_score>
      <Hsp_evalue>1.20386e-61</Hsp_evalue>
      <Hsp_query-from>234</Hsp_query-from>
      <Hsp_query-to>1382</Hsp_query-to>
      <Hsp_hit-from>62</Hsp_hit-from>
      <Hsp_hit-to>424</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>127</Hsp_identity>
      <Hsp_positive>212</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>386</Hsp_align-len>
      <Hsp_qseq>RAVLIDMEEGVVNELLQGPLRDVFDQKQLITDVSGSGNNWAVGNKVYGAQFREKILERLRVTAEHCDSLQCFFLIHSMXXXXXXXXXXFVLRLLEDEFPDVHRFVMALYPSAE-DDVVTSPYNSVLAMRELTEHADCVLPIENQALVDIVNKINHAAALGKSVRSQTTLSSSHGCLKGQEKPFDTMNNIVANLMLNMTSSSRFEGSLNVDLNEITMNLVPFPRLHYLVSSLTPLYALADVALPPRRLDQMFSDAFSKENQLLRVDPRRSLYLACALMVRGNVQLSDVRRNIERL--KPSLHFVDWNEEGWKTGLCSVPPVGYPHSLLALANNTCVKHTFADIQERFARLYRRKAHLHHYTDVEGMELSCFTEAASSLASVIEEYNQ</Hsp_qseq>
      <Hsp_hseq>RSINVDLEPGTIDAVRNSAIGNLFRPDNYIFGQSSAGNVWAKGHYTEGAELVDSVMDVIRREAEGCDSLQGFQITHSLGGGTGSGMGTLLISKIREEFPDRMMATFSVLPSPKTSDTVVEPYNATLSVHQLVEHSDETFCIDNEALYDICQR----------------------TLKLNQPSYGDLNNLVSSVMSGVTTSLRYPGQLNSDLRKLAVNLVPFPRLHFFMVGYAPLTAIGSQSFRSLTVPELTQQMFDAKNMMAAADPRNGRYLTVAAFFRGKVSVKEVEDEMHKVQSKNSDYFVEWIPNNVQTAVCSVAPQGLDMAATFIANSTSIQELFKRVGDQFSAMFKRKAFLHWYTS-EGMDELEFSEAESNMNDLVSEYQQ</Hsp_hseq>
      <Hsp_midline>R++ +D+E G ++ +    + ++F     I   S +GN WA G+   GA+  + +++ +R  AE CDSLQ F + HS+GGGTGSG+GT ++  + +EFPD      ++ PS +  D V  PYN+ L++ +L EH+D    I+N+AL DI  +                       LK  +  +  +NN+V+++M  +T+S R+ G LN DL ++ +NLVPFPRLH+ +    PL A+   +     + ++    F  +N +   DPR   YL  A   RG V + +V   + ++  K S +FV+W     +T +CSV P G   +   +AN+T ++  F  + ++F+ +++RKA LH YT  EGM+   F+EA S++  ++ EY Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YLR212C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:564860:566281:-1 gene:YLR212C transcript:YLR212C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TUB4 description:Gamma-tubulin; involved in nucleating microtubules from both the cytoplasmic and nuclear faces of the spindle pole body; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004202]</Hit_def>
  <Hit_accession>YLR212C</Hit_accession>
  <Hit_len>473</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>106.301</Hsp_bit-score>
      <Hsp_score>264</Hsp_score>
      <Hsp_evalue>1.37125e-24</Hsp_evalue>
      <Hsp_query-from>234</Hsp_query-from>
      <Hsp_query-to>1376</Hsp_query-to>
      <Hsp_hit-from>65</Hsp_hit-from>
      <Hsp_hit-to>437</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>96</Hsp_identity>
      <Hsp_positive>184</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>398</Hsp_align-len>
      <Hsp_qseq>RAVLIDMEEGVVNELLQGPLRDVFDQKQ--LITDVSGSGNNWAVGNKVYGAQFREKILERLRVTAEHCDSLQCFFLIHSMXXXXXXXXXXFVLRLLEDEFPDVHRFVMALYPSAEDDVVTSPYNSVLAMRELTEHADCVLPIENQALVDIVNKINHAAALGKSVRSQTTLSSSHGCLKGQEKPFDTMNNIVANLMLNMTSSSRFEGSLNVDLNEITMNLVPFPRLHYLVSSLTPL---YALADVALPPRRLDQMFSDAFSKENQLLRVDPRRSLYLACALMVRGNVQLSDVRRNIERLKPSLHFVDWNEE------GWKTGLCSVPPVGYPHSLLALANNTCVKHTFADIQERFARLYRRKAHLHHYTDVEGMELSC------FTEAASSLASVIEEY</Hsp_qseq>
      <Hsp_hseq>RAIMMDSEPSVIADV-ENTFRGFFDPRNTWVASDGASAGNSWANGYDI-GTRNQDDILNKIDKEIDSTDNFEGFQLLHSVAGGTGSGLGSNLLEALCDRYPKKILTTYSVFPARSSEVVVQSYNTILALRRLIEDSDATVVFDNASLLNISGKV----------------------FRNPNIDLQHTNQLISTIISSVTNSIRFPSYMYSSMSSIYSTLIPSPELHFLSPSFTPFTSDYIHDDIAHKGHSSYDVMLDLLDPSNSLVSTAMNNPTYFNVYNTIIGNVEPRQISRAMTKLQQRIKFPSWSSSAMHVNIGRRSPYLPLQPNENEVSGMMLSNMSTVVNVFENACNTFDKVFAKGAFLNNY-NVGDLFQSMQNVQDEFAESREVVQSLMEDY</Hsp_hseq>
      <Hsp_midline>RA+++D E  V+ ++ +   R  FD +   + +D + +GN+WA G  + G + ++ IL ++    +  D+ + F L+HS+ GGTGSGLG+ +L  L D +P       +++P+   +VV   YN++LA+R L E +D  +  +N +L++I  K+                       +         N +++ ++ ++T+S RF   +   ++ I   L+P P LH+L  S TP    Y   D+A        +  D     N L+        Y      + GNV+   + R + +L+  + F  W+        G ++    + P     S + L+N + V + F +    F +++ + A L++Y +V  +  S       F E+   + S++E+Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1566694363</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

