<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0058468-RA transcript Note:&quot;Similar to Chek2 Serine/threonine-protein kinase Chk2 (Mus musculus)&quot; offset:2 AED:0.33 eAED:0.33 QI:2|0|0|0.62|0.57|0.62|8|0|325</BlastOutput_query-def>
  <BlastOutput_query-len>980</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058468-RA transcript Note:&quot;Similar to Chek2 Serine/threonine-protein kinase Chk2 (Mus musculus)&quot; offset:2 AED:0.33 eAED:0.33 QI:2|0|0|0.62|0.57|0.62|8|0|325</Iteration_query-def>
  <Iteration_query-len>980</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>105.916</Hsp_bit-score>
      <Hsp_score>263</Hsp_score>
      <Hsp_evalue>6.65566e-26</Hsp_evalue>
      <Hsp_query-from>135</Hsp_query-from>
      <Hsp_query-to>974</Hsp_query-to>
      <Hsp_hit-from>99</Hsp_hit-from>
      <Hsp_hit-to>413</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>89</Hsp_identity>
      <Hsp_positive>148</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>322</Hsp_align-len>
      <Hsp_qseq>DYSSNGTYINGEKVGKNQRHVLMNNAEISIALPTHRAFVFSNLARYEESHWPE-------------EIKKKYIITRTLGSTGTAVPLLTRFPRD----------------SGVFGEVKLAFHKGSERKVAIKVVPKRGLPIPQSSCRDVKTEADILKKLKHPCIITLEDAF-----DSADALYLVLELMEGGELFNR-VKQGALPEHNAKLIFYQLVLAVQ--ARQPFRFPELAGLTIGGNVARVLRAFPCE-----RPSRRASLPRQVSDFGLSRFVGEQYLMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLFI</Hsp_qseq>
      <Hsp_hseq>DKSRNGTFINGNRLVK-KDYILKNGDRIVFGKSCSFLFKYASSSSTDIENDDEKVSSESRSYKNDDEVFKKPQISATSSQNATTSAAIRKLNKTRPVSFFDKYLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQND-DQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITR--RENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTK---KGYTSKVDLWSAGVILYV</Hsp_hseq>
      <Hsp_midline>D S NGT+ING ++ K + ++L N   I         F +++ +  +  +  E             E+ KK  I+ T     T    + +  +                 +G +  VK A +K + ++VA+K+   +     Q   +  + E +IL +++HP I+ L D+F      S    YLVLE ++ GELF R V++  L +  +K +F QL+  ++    Q     ++    I  N+ R  R  P +            +  +++DFGL++F GE     +LCGTP+Y APEVL      GYT  VD WS GV+L++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>106.301</Hsp_bit-score>
      <Hsp_score>264</Hsp_score>
      <Hsp_evalue>7.89308e-26</Hsp_evalue>
      <Hsp_query-from>96</Hsp_query-from>
      <Hsp_query-to>974</Hsp_query-to>
      <Hsp_hit-from>90</Hsp_hit-from>
      <Hsp_hit-to>400</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>85</Hsp_identity>
      <Hsp_positive>149</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>326</Hsp_align-len>
      <Hsp_qseq>QRCLCQDQEVFLEDYSSNGTYINGEKVGKNQRHVLMNNAEISIALPTHRA------FVFSNLARYEESHWPEEIKKKYIITRTLGSTG----TAVPLL---TRFPRD---------SGVFGEVKLAFHKGSERKVAIKVVPKRGLPIPQSSCRDVKTEADILKKLKHPCIITLEDAFDSADALYLVLELMEGGELFNRV-KQGALPEHNAKLIFYQLVLAVQARQPFRFPELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFGLSRFVGEQYLMRSLCGTPAYQAPEVLASCGL----------GGYTRAVDCWSLGVLLFI</Hsp_qseq>
      <Hsp_hseq>QILLGEDGNLLLNDISTNGTWLNGQKVEKNSNQLLSQGDEITVGVGVESDILSLVIFINDKFKQCLEQNKVDRIRSNLKNTSKIASPGLTSSTASSMVANKTGIFKDFSIIDEVVGQGAFATVKKAIERTTGKTFAVKIISKRKVI---GNMDGVTRELEVLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAI------KYIHSMGIS-----HRDLKPDNILIEQDDPVLVK-ITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYV</Hsp_hseq>
      <Hsp_midline>Q  L +D  + L D S+NGT++NG+KV KN   +L    EI++ +           F+     +  E +  + I+     T  + S G    TA  ++   T   +D          G F  VK A  + + +  A+K++ KR +     +   V  E ++L+KL HP I+ L+  ++  ++ Y+V+E + GG+L + V   GA+ E   + I  Q++ A+      ++    G++      R L+            L + ++DFGL++  G    M++ CGT AY APEV+                 Y+  VD WS+G L+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>98.9821</Hsp_bit-score>
      <Hsp_score>245</Hsp_score>
      <Hsp_evalue>1.15373e-23</Hsp_evalue>
      <Hsp_query-from>300</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>34</Hsp_hit-from>
      <Hsp_hit-to>230</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>226</Hsp_align-len>
      <Hsp_qseq>KKKYIITRTLGSTGTAVPLLTRFPRDSGVFGEVKLAFHKGSERKVAIKVVPKRGLPIPQSSCRDVKTEADILKKLKHPCIITLEDAFDSADALYLVLELMEGGELFNRV-KQGALPEHNAKLIFYQLVLAVQARQPFRFPELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFGLS-RFVGEQYLMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLF</Hsp_qseq>
      <Hsp_hseq>KKKYVFGKTLGA---------------GTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNI-----------VHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHG---KPCDIWSIGVITY</Hsp_hseq>
      <Hsp_midline>KKKY+  +TLG+               G FG V+ A +  +   VA+K++ K+ L   +     +  E DIL++L HP I+  +D F+S D  Y++ +L +GGELF+R+ K+G   E +A  I  +++ AV+                  V R L+        +    P  V+DFG++ R   ++ L+    G+  Y APEVL   G G   +  D WS+GV+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>97.8265</Hsp_bit-score>
      <Hsp_score>242</Hsp_score>
      <Hsp_evalue>4.5423e-23</Hsp_evalue>
      <Hsp_query-from>309</Hsp_query-from>
      <Hsp_query-to>974</Hsp_query-to>
      <Hsp_hit-from>55</Hsp_hit-from>
      <Hsp_hit-to>244</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>223</Hsp_align-len>
      <Hsp_qseq>YIITRTLGSTGTAVPLLTRFPRDSGVFGEVKLAFHKGSERKVAIKVVPKRGLPIPQSSCRDVKTEADILKKLKHPCIITLEDAFDSADALYLVLELMEGGELFNR-VKQGALPEHNAKLIFYQLVLAVQARQPFRFPELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFGLSRFVGEQYLMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLFI</Hsp_qseq>
      <Hsp_hseq>YQIVKTLGE---------------GSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGR-IEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKI--------------VHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAG--PEVDVWSCGVILYV</Hsp_hseq>
      <Hsp_midline>Y I +TLG                G FG+VKLA+H  + +KVA+K++ K+ L       R ++ E   L+ L+HP II L D   S D + +V+E   G ELF+  V++  + E  A+  F Q++ AV+     +               V R    E       L  +++DFGLS  + +   +++ CG+P Y APEV++     G    VD WS GV+L++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>95.1301</Hsp_bit-score>
      <Hsp_score>235</Hsp_score>
      <Hsp_evalue>2.27806e-22</Hsp_evalue>
      <Hsp_query-from>300</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>44</Hsp_hit-from>
      <Hsp_hit-to>240</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>226</Hsp_align-len>
      <Hsp_qseq>KKKYIITRTLGSTGTAVPLLTRFPRDSGVFGEVKLAFHKGSERKVAIKVVPKRGLPIPQSSCRDVKTEADILKKLKHPCIITLEDAFDSADALYLVLELMEGGELFNRV-KQGALPEHNAKLIFYQLVLAVQARQPFRFPELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFGLSR-FVGEQYLMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLF</Hsp_qseq>
      <Hsp_hseq>RTNYIFGRTLGA---------------GSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNV-----------VHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGHG---KPCDIWSIGVITY</Hsp_hseq>
      <Hsp_midline>+  YI  RTLG+               G FG V+ A    +   VAIK++ K+ L       + +  E  IL+KL HP I++ +D F+S D  Y+V +L  GGELF+R+  +G   E +A  I  Q++ AV+                  V R L+        +  + P  ++DFG+++   GE+ L+    G+  Y APEVL   G G   +  D WS+GV+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.5893</Hsp_bit-score>
      <Hsp_score>231</Hsp_score>
      <Hsp_evalue>1.54371e-21</Hsp_evalue>
      <Hsp_query-from>381</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>28</Hsp_hit-from>
      <Hsp_hit-to>222</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>211</Hsp_align-len>
      <Hsp_qseq>GVFGEVKLAFHKGSERKVAIKVVPK--------RGLPIPQSSCRD-----VKTEADILKKLKHPCIITLEDAFDSADALYLVLELMEGGELFNR-VKQGALPEHNAKLIFYQLVLAVQARQPFRFPELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFGLSRFVGEQYLMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLF</Hsp_qseq>
      <Hsp_hseq>GSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHAL-----------GIVHRDLKP---ENLLLDHKYNIKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQGF--ASDVWSCGVILF</Hsp_hseq>
      <Hsp_midline>G  G+V+LA +  + ++ A+KV+ K         G  I  S+  D     ++ E  I+K L HP ++ L D +++   LYLVLE  E GELFN  V++G LPEH A   F Q+++ V                 G V R L+    E          +++DFG++    E  L+ + CG+P Y APE+++     G+  A D WS GV+LF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.5077</Hsp_bit-score>
      <Hsp_score>223</Hsp_score>
      <Hsp_evalue>1.67135e-20</Hsp_evalue>
      <Hsp_query-from>381</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>30</Hsp_hit-from>
      <Hsp_hit-to>218</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>205</Hsp_align-len>
      <Hsp_qseq>GVFGEVKLAFHKGSERKVAIKVVPKRGLPIPQSSCRD-------VKTEADILKKLKHPCIITLEDAFDSADALYLVLELMEGGELFNR-VKQGALPEHNAKLIFYQLVLAVQARQPFRFPELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFGLSRFVGEQYLMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLF</Hsp_qseq>
      <Hsp_hseq>GSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIII--------------GISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGF--ASDVWSCGVILF</Hsp_hseq>
      <Hsp_midline>G  G+V+LA H+ +  + A+KV+ K       +   D       ++ E  I+K L HP +++L D +++ + LYL+LE  E GELFN  V  G LPE  A   F Q+++              G++    +  V R    E     +    +++DFG++    +  L+ + CG+P Y APE+++     G+  A D WS GV+LF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>82.8037</Hsp_bit-score>
      <Hsp_score>203</Hsp_score>
      <Hsp_evalue>2.82421e-18</Hsp_evalue>
      <Hsp_query-from>378</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>78</Hsp_hit-from>
      <Hsp_hit-to>256</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>205</Hsp_align-len>
      <Hsp_qseq>SGVFGEVKLAFHKGSERKVAIKVVPKRGLPIPQSSCRDVKTEADILKKLKHPCIITLEDAFDSADALYLVLELMEGGELFNRVKQGA-LPEHNAKLIFYQLVLAVQARQPFRF------PELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFGLSRFVGEQYLMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLF</Hsp_qseq>
      <Hsp_hseq>TGSFGRVHLVRSVHNGRYYAIKVLKKQQV-VKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHI--------------------KITDFGFAKEV--QTVTWTLCGTPDYIAPEVITT---KPYNKSVDWWSLGVLIY</Hsp_hseq>
      <Hsp_midline>+G FG V L     + R  AIKV+ K+ + +          E  +LK ++HP +I +   F  A  +++V++ +EGGELF+ +++    P   AK    +++LA++             PE   L   G++                    +++DFG ++ V  Q +  +LCGTP Y APEV+ +     Y ++VD WSLGVL++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.1889</Hsp_bit-score>
      <Hsp_score>204</Hsp_score>
      <Hsp_evalue>4.38667e-18</Hsp_evalue>
      <Hsp_query-from>165</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>12</Hsp_hit-from>
      <Hsp_hit-to>243</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>82</Hsp_identity>
      <Hsp_positive>122</Hsp_positive>
      <Hsp_gaps>55</Hsp_gaps>
      <Hsp_align-len>278</Hsp_align-len>
      <Hsp_qseq>GEKVGKNQRHVLMNNAEISIALPTHRAFVFSNLARYEESHWPEEIKKKYIITRTLGSTGTAVPLLTRFPRDSGVFGEVKLAFHKGSE-----RKVAIKVVPKRGLPIPQSSCRDVKT--EADILKKLKHPCIITLEDAFDSADALYLVLELMEGGELFNRV-KQGALPEHNAKLIFYQLVLAVQARQPFRFPELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFG-LSRFVGEQYLMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLF</Hsp_qseq>
      <Hsp_hseq>GNVVTDRDRHSLQRNNEI--LHPIHKN------QRKHATFGP------YIIGSTLGE---------------GEFGKVKLGWTKASSSNEVPKQVAIKLI--RRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVN------YMHYKGL--------VHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTK-AYEARKADVWSCGVILY</Hsp_hseq>
      <Hsp_midline>G  V    RH L  N EI    P H+        R   +  P      YII  TLG                G FG+VKL + K S      ++VAIK++  R   I + + +++K   E + LK L HP II LE+   ++  + +VLE + GGE +  + ++  L E +A  +F QL+  V       +    GL        V R    E           ++DFG ++ F  +  LM++ CG+P Y APE++ S       R  D WS GV+L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.8777</Hsp_bit-score>
      <Hsp_score>198</Hsp_score>
      <Hsp_evalue>2.72828e-17</Hsp_evalue>
      <Hsp_query-from>381</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>421</Hsp_hit-from>
      <Hsp_hit-to>603</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>207</Hsp_align-len>
      <Hsp_qseq>GVFGEVKLAFHKGSERKVAIKVVPKRGLPIPQSSCRDVKTEADIL---KKLKHPCIITLEDAFDSADALYLVLELMEGGELFNRV-KQGALPEHNAKLIFYQLVLAVQARQPFRF------PELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFGLSRFVGEQYLMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLF</Hsp_qseq>
      <Hsp_hseq>GTFGQVYQVKKKDTQRIYAMKVLSKKVI-VKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIA--------------------LCDFGLSK-ADLKDRTNTFCGTTEYLAPELL--LDETGYTKMVDFWSLGVLIF</Hsp_hseq>
      <Hsp_midline>G FG+V     K ++R  A+KV+ K+ + + ++       E +IL        P I+ L+ +F +   LYLV + M GGELF  + K+G   E  AK    +LVLA++             PE   L   GN+A                    + DFGLS+    +    + CGT  Y APE+L      GYT+ VD WSLGVL+F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.2554</Hsp_bit-score>
      <Hsp_score>186</Hsp_score>
      <Hsp_evalue>5.44015e-16</Hsp_evalue>
      <Hsp_query-from>378</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>95</Hsp_hit-from>
      <Hsp_hit-to>273</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>199</Hsp_align-len>
      <Hsp_qseq>SGVFGEVKLAFHKGSERKVAIKVVPKRGLPIPQSSCRDVKTEADILKKLKHPCIITLEDAFDSADALYLVLELMEGGELFNRVKQGA-LPEHNAKLIFYQLVLAVQARQPFRFPELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFGLSRFVGEQYLMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLF</Hsp_qseq>
      <Hsp_hseq>TGSFGRVHLIRSRHNGRYYAMKVL-KKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEY--------LHSKDI------IYRDLKPENILLDKNGHIKITDFGFAKYVPD--VTYTLCGTPDYIAPEVVSTK---PYNKSIDWWSFGILIY</Hsp_hseq>
      <Hsp_midline>+G FG V L   + + R  A+KV+ K+ + +          E  +L  + HP II +   F  A  ++++++ +EGGELF+ +++    P   AK    ++ LA++         L    I      + R    E      +   +++DFG +++V +  +  +LCGTP Y APEV+++     Y +++D WS G+L++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.2554</Hsp_bit-score>
      <Hsp_score>186</Hsp_score>
      <Hsp_evalue>8.49726e-16</Hsp_evalue>
      <Hsp_query-from>381</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>356</Hsp_hit-from>
      <Hsp_hit-to>536</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>205</Hsp_align-len>
      <Hsp_qseq>GVFGEVKLAFHKGSERKVAIKVVPKRGLPIPQSSCRDVKTEADILKKLKHPCIITLEDAFDSADALYLVLELMEGGELFNRV-KQGALPEHNAKLIFYQLVLAVQARQPFRF------PELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFGLSRF-VGEQYLMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLF</Hsp_qseq>
      <Hsp_hseq>GSFGKVMQVRKKDTQKVYALKAI-RKSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIA--------------------LCDFGLCKLNMKDDDKTDTFCGTPEYLAPELL--LGL-GYTKAVDWWTLGVLLY</Hsp_hseq>
      <Hsp_midline>G FG+V     K +++  A+K + ++   + +S       E  +L ++  P I+ L+ +F S + LY VL  + GGELF  + K+G      A+    +L+ A+              PE   L   G++A                    + DFGL +  + +     + CGTP Y APE+L   GL GYT+AVD W+LGVLL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.2554</Hsp_bit-score>
      <Hsp_score>186</Hsp_score>
      <Hsp_evalue>8.64154e-16</Hsp_evalue>
      <Hsp_query-from>381</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>333</Hsp_hit-from>
      <Hsp_hit-to>533</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>207</Hsp_align-len>
      <Hsp_qseq>GVFGEVKLAFHKGSERKVAIKVVPKRGLPIPQSSCRDVKTEADILKKLKHPCIITLEDAFDSADALYLVLELMEGGELFNRV---KQGALPEHNAKLIFYQLVLAVQARQPFRF------PELAGLTIGGNVARVLRAFPCERPSRRASLPR-QVSDFGLSRFVGEQYLMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLF</Hsp_qseq>
      <Hsp_hseq>GDVGKVYLVRERDTNQIFALKVLNKHEM-IKRKKIKRVLTEQEILATSDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHV--MLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRG---NGHTAAVDWWTLGILIY</Hsp_hseq>
      <Hsp_midline>G  G+V L   + + +  A+KV+ K  + I +   + V TE +IL    HP I+TL  +F + D LYL +E   GGE F  +   K   + E +AK    ++V A++      F      PE   L   G+V  +L  F     +  +  P  + S +  ++   + +   S  GT  Y APEV+      G+T AVD W+LG+L++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.485</Hsp_bit-score>
      <Hsp_score>184</Hsp_score>
      <Hsp_evalue>1.03997e-15</Hsp_evalue>
      <Hsp_query-from>378</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>96</Hsp_hit-from>
      <Hsp_hit-to>274</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>205</Hsp_align-len>
      <Hsp_qseq>SGVFGEVKLAFHKGSERKVAIKVVPKRGLPIPQSSCRDVKTEADILKKLKHPCIITLEDAFDSADALYLVLELMEGGELFNRVKQGA-LPEHNAKLIFYQLVLAVQARQPFRF------PELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFGLSRFVGEQYLMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLF</Hsp_qseq>
      <Hsp_hseq>TGSFGRVHLIRSNHNGRFYALKTLKKHTI-VKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHI--------------------KITDFGFAKYVPD--VTYTLCGTPDYIAPEVVST---KPYNKSVDWWSFGVLIY</Hsp_hseq>
      <Hsp_midline>+G FG V L     + R  A+K + K  + +          E  +L  + HP II +   F  +  +++V++ +EGGELF+ +++    P   AK    ++ LA++             PE   L   G++                    +++DFG +++V +  +  +LCGTP Y APEV+++     Y ++VD WS GVL++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>1.01922e-14</Hsp_evalue>
      <Hsp_query-from>381</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>505</Hsp_hit-from>
      <Hsp_hit-to>708</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>210</Hsp_align-len>
      <Hsp_qseq>GVFGEVKLAFHKGSERKVAIKVVPKRGLPIPQSSCRDVKTEADILKKLKHPCIITLEDAFDSADALYLVLELMEGGELFNRV---KQGALPEHNAKLIFYQLVLAVQARQPFRF------PELAGLTIGGNVARVLRAFPCERPSRRASLP----RQVSDFGLSRFVGEQYLMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLF</Hsp_qseq>
      <Hsp_hseq>GDVGKVFLVREKKTNRVYALKVLSKDEM-IKRNKIKRVLTEQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSGHI--MLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRG---NGHTAAVDWWTLGILIY</Hsp_hseq>
      <Hsp_midline>G  G+V L   K + R  A+KV+ K  + I ++  + V TE +IL    HP I+TL  +F S D LYL +E   GGE F  +   K   + E +A+    ++  A++      F      PE   L   G++  +L  F     ++ + +P       S    ++   + +   S  GT  Y APEV+      G+T AVD W+LG+L++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.4034</Hsp_bit-score>
      <Hsp_score>176</Hsp_score>
      <Hsp_evalue>1.61547e-14</Hsp_evalue>
      <Hsp_query-from>381</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>833</Hsp_hit-from>
      <Hsp_hit-to>1015</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>203</Hsp_align-len>
      <Hsp_qseq>GVFGEVKLAFHKGSERKVAIKVVPKRGLPIPQSSCRDVKTEADIL---KKLKHPCIITLEDAFDSADALYLVLELMEGGELFNRVKQGALPEHNAKLIFYQLVLAVQARQPFRFPELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFGLSR---FVGEQYLMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLF</Hsp_qseq>
      <Hsp_hseq>GNFGKVILSKSKNTDRLCAIKVLKKDNI-IQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQRLSVRRAKFYAAEVLLAL------KYFHDNGV--------IYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNR--TSTFCGTPEFMAPEILKE---QEYTKAVDWWAFGVLLY</Hsp_hseq>
      <Hsp_midline>G FG+V L+  K ++R  AIKV+ K  + I        + E  +     K KHP +  L  +F + + +Y  +E + GG+L   V+   L    AK    +++LA+      ++    G+        + R    E          +++D+GL +   + G +    + CGTP + APE+L       YT+AVD W+ GVLL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.4034</Hsp_bit-score>
      <Hsp_score>176</Hsp_score>
      <Hsp_evalue>1.62122e-14</Hsp_evalue>
      <Hsp_query-from>381</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>50</Hsp_hit-from>
      <Hsp_hit-to>243</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>213</Hsp_align-len>
      <Hsp_qseq>GVFGEVKLAFHKGSE----------RKVAIKVVPKRGLPIPQSSCRDVKTEADILKKLKHPCIITLEDAFDSADALYLVLELMEGGELFNRV-KQGALPEHNAKLIFYQLVLAVQARQP----FRFPELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFG-LSRFVGEQYLMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLF</Hsp_qseq>
      <Hsp_hseq>GEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRKEVKIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLV------------------ITDFGFVNEFCSRNELMKTSCGSPCYAAPELVISAE-PYEARKADIWSCGVILY</Hsp_hseq>
      <Hsp_midline>G FG+VKL + K             ++VAIK++ +  +         +  E + LK L HP I+ LE+   ++  + +VLE   GGE +  + K+  L E NA  +F QL+  V          R  +L  L +  N   V                  ++DFG ++ F     LM++ CG+P Y APE++ S       R  D WS GV+L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>4.05612e-14</Hsp_evalue>
      <Hsp_query-from>381</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>353</Hsp_hit-from>
      <Hsp_hit-to>533</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>206</Hsp_align-len>
      <Hsp_qseq>GVFGEVKLAFHKGSERKVAIKVVPKRGLPIPQSSCRDVKTEADILKKLKHPCIITLEDAFDSADALYLVLELMEGGELFNRVK-QGALPEHNAKLIFYQLVLAVQARQPFRF------PELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFGLSRF-VGEQYLMRSLCGTPAYQAPEVLASCGLG-GYTRAVDCWSLGVLLF</Hsp_qseq>
      <Hsp_hseq>GSFGKVMQVRKKDTQKIYALKAL-RKAYIVSKCEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIA--------------------LCDFGLCKLNMKDNDKTDTFCGTPEYLAPEIL----LGQGYTKTVDWWTLGILLY</Hsp_hseq>
      <Hsp_midline>G FG+V     K +++  A+K + ++   + +        E  +L ++  P I+ L+ +F S + LYLVL  + GGELF  ++ +G      ++    +L+ A+ +            PE   L   G++A                    + DFGL +  + +     + CGTP Y APE+L    LG GYT+ VD W+LG+LL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>5.17379e-14</Hsp_evalue>
      <Hsp_query-from>381</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>90</Hsp_hit-from>
      <Hsp_hit-to>306</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>54</Hsp_gaps>
      <Hsp_align-len>234</Hsp_align-len>
      <Hsp_qseq>GVFGEVKLAFHKGSERKVAIKVVPKR-----------------------GLPIPQSSCRD-----------VKTEADILKKLKHPCIITLEDAFDSADALYLVLELMEGGELFNR-VKQGALPEHNAKLIFYQLVLAVQARQPFRFPELAGLTIGGNVARVLRA--FPCERPSRRASLPRQVSDFGLSRFVGEQYLMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLF</Hsp_qseq>
      <Hsp_hseq>GSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNI-----------CHRDLKPENLLLDKKNRRI----KIADFGMAALELPNKLLKTSCGSPHYASPEIVM--GRPYHGGPSDVWSCGIVLF</Hsp_hseq>
      <Hsp_midline>G  G V+LA +  + +  AIK+VPK+                        +  P  + R+           ++ E  I+K + H  ++ L + +++   LYLVLE ++GGELF+  V +G LPE  A   F Q+V  V     F               R L+      ++ +RR     +++DFG++       L+++ CG+P Y +PE++   G   +    D WS G++LF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>4.5551e-13</Hsp_evalue>
      <Hsp_query-from>126</Hsp_query-from>
      <Hsp_query-to>974</Hsp_query-to>
      <Hsp_hit-from>86</Hsp_hit-from>
      <Hsp_hit-to>377</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>63</Hsp_gaps>
      <Hsp_align-len>319</Hsp_align-len>
      <Hsp_qseq>FLEDYSSNGTYINGEKVGKNQRHVLMNNAEISIALPTHRA------FVFSNLARYEESHWPE---------EIKKKYIITRTLGSTGTAVPLLTRFPRDSGVFGEVKLAFHKGSERKVAIKVVPKR-GLPIPQSSCRDVKTEADILKKLKHPCIITLEDAF-DSADALYLVLELMEGGELFNRVKQG----ALPEHNAKLIFYQLVLAVQARQPFRFPELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFGLSRFVG-EQYLMRSLCGTPAYQAPEV--------------LASCGLGGYTRAVDCWSLGVLLFI</Hsp_qseq>
      <Hsp_hseq>YVKDCSLNGTYLNGLLLKRDKTYLLKHCDVIELSQGSEENDIKKTRLVFMINDDLQSSLDPKLLDQMGFLREVDQWEITNRIVGN---------------GTFGHV-LITHNSKERDEDVCYHPENYAVKIIKLKPNKFDKEARILLRLDHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQIL---QALNYLHDQDIVHRDLKLDNILLCTPEPCTRIV--------LADFGIAKDLNSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHI</Hsp_hseq>
      <Hsp_midline>+++D S NGTY+NG  + +++ ++L +   I ++  +          VF      + S  P+         E+ +  I  R +G+               G FG V L  H   ER   +   P+   + I +        EA IL +L HP II +   F D  + LY+  +L+ GG+LF+ + +G    ++ E  + LI +Q++   QA       ++    +  +   +    PC R          ++DFG+++ +   +  M ++ GTP Y APEV               A+    GY    D WSLGV+  I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>8.07917e-12</Hsp_evalue>
      <Hsp_query-from>381</Hsp_query-from>
      <Hsp_query-to>968</Hsp_query-to>
      <Hsp_hit-from>22</Hsp_hit-from>
      <Hsp_hit-to>213</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>213</Hsp_align-len>
      <Hsp_qseq>GVFGEVKLAFHKGSERKVAIKVVPKRGLPI-PQSSCRDVKTEADILKKLKHPCIITL-----EDAFDSADALYLVLELMEGGELFNRVKQGALPEHNAKLIFYQLVLAVQARQPFRFPELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFGLSRFV-----------GEQYLMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLL</Hsp_qseq>
      <Hsp_hseq>GAYGVVCSATHKPTGEIVAIKKIEPFDKPLFALRTLREIK----ILKHFKHENIITIFNIQRPDSFENFNEVYIIQELMQT-DLHRVISTQMLSDDHIQYFIYQTLRAVKVLH------------GSNV--IHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSA--KYSRAMDVWSCGCIL</Hsp_hseq>
      <Hsp_midline>G +G V  A HK +   VAIK +     P+    + R++K    ILK  KH  IIT+      D+F++ + +Y++ ELM+  +L   +    L + + +   YQ + AV+               G NV  + R          ++   +V DFGL+R +           G+Q  M     T  Y+APEV+ +     Y+RA+D WS G +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>2.08443e-11</Hsp_evalue>
      <Hsp_query-from>378</Hsp_query-from>
      <Hsp_query-to>974</Hsp_query-to>
      <Hsp_hit-from>107</Hsp_hit-from>
      <Hsp_hit-to>315</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>225</Hsp_align-len>
      <Hsp_qseq>SGVFGEVKLAFHKGSERKVAIKVV---------PKRGLPIPQSS--------------CRDVKT--EADILKKLKHPCIITLEDAFDSADALYLVLELMEGGELFNRVKQ-GALPEHNAKLIFYQLVLAVQARQPFRFPELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFGLSRFVGEQYLMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLFI</Hsp_qseq>
      <Hsp_hseq>AGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESEILERQKRLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLH------------ANNI--VHRDLKIENIMISSSGEIKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELLKAQPYTG--PEVDIWSFGIVLYV</Hsp_hseq>
      <Hsp_midline>+G  G+VKL  H+ ++    IK+V          +  LP P++                RD +T  EA + + L HP I  L +    ++  Y++ E + GG+L + + Q G+L EH+A+     +  A+Q                 N+  V R    E     +S   ++ DFGLS     +  + + CG+  + APE+L +    G    VD WS G++L++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>4.90768e-11</Hsp_evalue>
      <Hsp_query-from>480</Hsp_query-from>
      <Hsp_query-to>974</Hsp_query-to>
      <Hsp_hit-from>58</Hsp_hit-from>
      <Hsp_hit-to>214</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>179</Hsp_align-len>
      <Hsp_qseq>SCRDVKTEADILKKL-KHPCIITLEDAFDSADALYLVLELMEGGELFNRVKQGALPEHN-AKLIFYQLVLAVQ--------ARQPFRFPELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFGL-SRFVGEQYLMRSLC---GTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLFI</Hsp_qseq>
      <Hsp_hseq>SDKDITKEVVLQSKCSKHPNVLRLIDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIK-PENILLDKNGNL--------------------KLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEE-GYYADRTDIWSIGILLFV</Hsp_hseq>
      <Hsp_midline>S +D+  E  +  K  KHP ++ L D   S + ++++LE+ +GG+LF++++     + + A+  F QLV A+         A +  + PE   L   GN+                    +++DFGL S+F  +   +R      G+P Y APEVL S   G Y    D WS+G+LLF+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>5.12983e-11</Hsp_evalue>
      <Hsp_query-from>378</Hsp_query-from>
      <Hsp_query-to>974</Hsp_query-to>
      <Hsp_hit-from>128</Hsp_hit-from>
      <Hsp_hit-to>336</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>225</Hsp_align-len>
      <Hsp_qseq>SGVFGEVKLAFHKGSERKVAIKVVPK---------RGLPIPQSS--------------CRDVKT--EADILKKLKHPCIITLEDAFDSADALYLVLELMEGGELFNRVKQ-GALPEHNAKLIFYQLVLAVQARQPFRFPELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFGLSRFVGEQYLMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLFI</Hsp_qseq>
      <Hsp_hseq>AGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPPPKNEQDVLERQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIREH-------------QARKFARGIASALIYLHANNI-VHRDLKIENIMISDSSEIKIIDFGLSNIYDSRKQLHTFCGSLYFAAPELLKANPYTG--PEVDVWSFGVVLFV</Hsp_hseq>
      <Hsp_midline>+G  G+VKLA H+ +    A+K+V +         + LP P++                RD +T  EA + + L HP I  L +    ++  Y++ E + GG+L + + Q G++ EH             QAR+  R    A + +  N   V R    E      S   ++ DFGLS     +  + + CG+  + APE+L +    G    VD WS GV+LF+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>8.52478e-11</Hsp_evalue>
      <Hsp_query-from>498</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>128</Hsp_hit-from>
      <Hsp_hit-to>272</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>160</Hsp_align-len>
      <Hsp_qseq>TEADILKKLKHPCIITLEDAFDSADALYLVLELMEGGELFNRVKQ-GALPEHNAKLIFYQLVLAVQARQPFRFPELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFGLSRFVGEQYLMR-SLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLF</Hsp_qseq>
      <Hsp_hseq>SEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRV--------------IHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMG-KHSGHSFEVDIWSLGVMLY</Hsp_hseq>
      <Hsp_midline>+E  I K + HP I+   D F+    +Y++LE+   G L   +K+   L E   +    Q+  A++     R               + R          ++   ++ DFGL+  +  +   + ++CGTP Y APEVL      G++  VD WSLGV+L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>9.98586e-11</Hsp_evalue>
      <Hsp_query-from>501</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>202</Hsp_hit-from>
      <Hsp_hit-to>353</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>170</Hsp_align-len>
      <Hsp_qseq>EADILKKLKHPCIITLEDAFDSADALYLVLELMEGGELFNRVKQ-GALPEHNAKLIFYQLVLAVQARQPFRFPELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFGLSR------FVGEQ-----YLMRSLCGTPAYQAPEVLASCGLG-GYTRAVDCWSLGVLLF</Hsp_qseq>
      <Hsp_hseq>ERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDE--TTVSFY----AAEISCALRF-----LHTKGVVYRDLKPENC-LLNQRGHL--VLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEIL----LGKAYSQNCDWYSLGCLLY</Hsp_hseq>
      <Hsp_midline>E  IL +++HP I+ L  +F     LYL+L+ + GGELF  +K+ G L E    + FY    A +     RF     L   G V R L+   C   ++R  L   ++DFGLS+       V E+       + S+ GTP Y APE+L    LG  Y++  D +SLG LL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>3.69936e-10</Hsp_evalue>
      <Hsp_query-from>381</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>27</Hsp_hit-from>
      <Hsp_hit-to>208</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>200</Hsp_align-len>
      <Hsp_qseq>GVFGEVKLAFHKGSERKVAIKVVPKRGLPIPQSSCRDVKTEADILKKLKHPCIITLEDAFDSADALYLVLELMEGG---ELFNRVKQGALPEHNAKLIFYQLVLAVQARQPFRFPELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFGLSRFVGEQYLMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLF</Hsp_qseq>
      <Hsp_hseq>GNFGDVYKAVDRVTQEIVAIKVV---NLEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQR--------------KIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRDTFVGTPYWMAPEVVC-CEVDGYNEKADIWSLGITTY</Hsp_hseq>
      <Hsp_midline>G FG+V  A  + ++  VAIKVV    L         +  E   L +LK P I           ++++V+E   GG   +L  R     LPE     I +++ L ++     R              ++ R               ++ DFG+S  +       +  GTP + APEV+  C + GY    D WSLG+  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>4.20097e-09</Hsp_evalue>
      <Hsp_query-from>426</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>49</Hsp_hit-from>
      <Hsp_hit-to>258</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>215</Hsp_align-len>
      <Hsp_qseq>RKVAIKVVPKRGLPIPQSSCRDVKTEADILKKLKHPCIITLEDAFDSADALYLVLE----------------LMEGGELFNRVKQGALPE-------HNAKLIFYQLVLAVQARQPFRFPELAGLTIGGNVARVLRAFPCERPSRR---------ASLP-RQVSDFGLSRFVGEQYLMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLF</Hsp_qseq>
      <Hsp_hseq>QHVAIKEVSRAKLK-NKKLLENLEIEIAILKKIKHPHIVGLIDCERTSTDFYLIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLA-SALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEIL---NYQKYNAKADLWSVGTVVF</Hsp_hseq>
      <Hsp_midline>+ VAIK V +  L   +    +++ E  ILKK+KHP I+ L D   ++   YL++E                LME   L   V +   P        H A ++ Y   LA  A +  R   L    I      +         S+           +LP  +++DFG +RF+    L  +LCG+P Y APE+L       Y    D WS+G ++F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>5.13686e-08</Hsp_evalue>
      <Hsp_query-from>411</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>396</Hsp_hit-from>
      <Hsp_hit-to>573</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>197</Hsp_align-len>
      <Hsp_qseq>HKGSERKVAIKVV-----PKRGLPIPQSSCRDVKTEADILKKLKHPCIITLEDAFDSADA-LYLVLELMEGG---ELFNRVKQGALPEHNAKLIFYQLVLAVQARQPFRFPELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFGLSRFVGEQYLMR-SLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLF</Hsp_qseq>
      <Hsp_hseq>HRVVGERVAIKQIRLSEQPKKQL---------IMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKET-------CQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQ---KGYDEKVDVWSLGIMLI</Hsp_hseq>
      <Hsp_midline>H+    +VAIK +     PK+ L         +  E  ++   +   I+   +A+   D  L++++E MEGG   ++ + V +    EH++ L   Q+   V+           GL    N   + R    +     +    +++DFG    + E+   R ++ GTP + APE++      GY   VD WSLG++L </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>2.9095e-07</Hsp_evalue>
      <Hsp_query-from>381</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>186</Hsp_hit-from>
      <Hsp_hit-to>406</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>232</Hsp_align-len>
      <Hsp_qseq>GVFGEVKLAFHKGSERKVAIKVVPKRGLPIPQSSCRDVKTEADILKKLKHPCIITLEDAFDSADALYLVLELMEGGELFN-RVKQGALPEHNAKLIFYQLVLAVQARQPFRF------PE----------------LAGLTIGGNVARVLR------------AFPCERPSRRASLPRQVSDFGLSRFVGEQYLMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLF</Hsp_qseq>
      <Hsp_hseq>GGYGQVYLARKKDTKEVCALKILNKK-LLFKLNETKHVLTERDILTTTRSEWLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINTRCLKSGHARFYISEMFCAVNALHDLGYTHRDLKPENFLIDAKGHIKLTDFGLAAGTISNERIESMKIRLEKIKDLEFPAFTEKSIEDRRKMYNQLRE-------KEINYANSMVGSPDYMALEVLEG---KKYDFTVDYWSLGCMLF</Hsp_hseq>
      <Hsp_midline>G +G+V LA  K ++   A+K++ K+ L    +  + V TE DIL   +   ++ L  AF    +LYL +E + GG+     +    L   +A+    ++  AV A     +      PE                LA  TI       ++            AF  +    R  +  Q+ +        E     S+ G+P Y A EVL       Y   VD WSLG +LF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YPR111W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:747306:749000:1 gene:YPR111W transcript:YPR111W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF20 description:Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006315]</Hit_def>
  <Hit_accession>YPR111W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>3.05107e-07</Hsp_evalue>
      <Hsp_query-from>381</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>178</Hsp_hit-from>
      <Hsp_hit-to>398</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>227</Hsp_align-len>
      <Hsp_qseq>GVFGEVKLAFHKGSERKVAIKVVPKRGLPIPQSSCRDVKTEADILKKLKHPCIITLEDAFDSADALYLVLELMEGGELFN-RVKQGALPEHNAKLIFYQLVLAVQARQPFRF------PELAGLTIGGNVARVLRAF-------PCERPSRRASLPRQVSDFGLSRFVGEQ--------YLMR--------SLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLF</Hsp_qseq>
      <Hsp_hseq>GGYGQVYLAKKKDSDEICALKILNKK-LLFKLNETNHVLTERDILTTTRSDWLVKLLYAFQDPESLYLAMEFVPGGDFRTLLINTRILKSGHARFYISEMFCAVNALHELGYTHRDLKPENFLIDATGHIK--LTDFGLAAGTVSNERIESMKIRLEEVKNLEFPAFTERSIEDRRKIYHNMRKTEINYANSMVGSPDYMALEVLEG---KKYDFTVDYWSLGCMLF</Hsp_hseq>
      <Hsp_midline>G +G+V LA  K S+   A+K++ K+ L    +    V TE DIL   +   ++ L  AF   ++LYL +E + GG+     +    L   +A+    ++  AV A     +      PE   +   G++   L  F         ER         +V +     F            + MR        S+ G+P Y A EVL       Y   VD WSLG +LF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>3.42975e-07</Hsp_evalue>
      <Hsp_query-from>411</Hsp_query-from>
      <Hsp_query-to>971</Hsp_query-to>
      <Hsp_hit-from>123</Hsp_hit-from>
      <Hsp_hit-to>292</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>192</Hsp_align-len>
      <Hsp_qseq>HKGSERKVAIKVVPKRGLPIPQSSCRDVKTEADILKKLKHPCIITLEDAFDSADALYLVLELMEGGELFNRVK-QGALPEHNAKLIFYQLVLAVQARQP----FRFPELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFGLSRFVGEQYLMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLLF</Hsp_qseq>
      <Hsp_hseq>HRSTGYICALKVMEKEEI-IKYNLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFN--NVIK----------------LTDFGWSIINPPENRRKTVCGTIDYLSPEMVES---REYDHTIDAWALGVLAF</Hsp_hseq>
      <Hsp_midline>H+ +    A+KV+ K  + I  +  +  + E +I   L HP +      F     +YL++E +  GE++  ++  G   +  A    YQ+  A+          R  +   + IG N   V++                ++DFG S     +   +++CGT  Y +PE++ S     Y   +D W+LGVL F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>4.07545e-07</Hsp_evalue>
      <Hsp_query-from>381</Hsp_query-from>
      <Hsp_query-to>968</Hsp_query-to>
      <Hsp_hit-from>22</Hsp_hit-from>
      <Hsp_hit-to>216</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>219</Hsp_align-len>
      <Hsp_qseq>GVFGEVKLAFHKGSERKVAIKVV-PKRGLPIPQSSCRDVKTEADILKKL-KHPCIITLED-----AFDSADALYLVLELMEGG--ELFNRVKQG--ALPEHNAKLIFYQLVLAVQ----ARQPFRFPELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFGLSRFVGEQY--------LMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLL</Hsp_qseq>
      <Hsp_hseq>GAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRTIREIK----LLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSN---------CD---------LKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLT--FQEYTTAMDIWSCGCIL</Hsp_hseq>
      <Hsp_midline>G +G V  A HK S  KVAIK + P         + R++K    +L+   +H  II++ D     + D  +A+YLV ELME    ++ N    G   L + + +   YQ++ A++    A+   R  + + L +  N         C+          +V DFGL+R +             M     T  Y+APE++ +     YT A+D WS G +L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.2914</Hsp_bit-score>
      <Hsp_score>116</Hsp_score>
      <Hsp_evalue>4.3185e-07</Hsp_evalue>
      <Hsp_query-from>381</Hsp_query-from>
      <Hsp_query-to>695</Hsp_query-to>
      <Hsp_hit-from>361</Hsp_hit-from>
      <Hsp_hit-to>465</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>106</Hsp_align-len>
      <Hsp_qseq>GVFGEVKLAFHKGSERKVAIKVVPKRGLPIPQSSCRDVKTEADILKKLKHPCIITLEDAFDSADALYLVLELMEGGELFNR-VKQGALPEHNAKLIFYQLVLAVQA</Hsp_qseq>
      <Hsp_hseq>GAFGEVRLVQKKDTGKIYAMKTLLKSEM-YKKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIET</Hsp_hseq>
      <Hsp_midline>G FGEV+L   K + +  A+K + K  +   +     VK E D+L     P +++L  +F  A  LYL++E + GG+L    ++     E   +    + +LA++ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>8.08877e-07</Hsp_evalue>
      <Hsp_query-from>339</Hsp_query-from>
      <Hsp_query-to>968</Hsp_query-to>
      <Hsp_hit-from>14</Hsp_hit-from>
      <Hsp_hit-to>207</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>217</Hsp_align-len>
      <Hsp_qseq>GTAVPLLTRF----PRDSGVFGEVKLAFHKGSERKVAIKVV--PKRGLPIPQSSCRDVKTEADILKKLKHPCIITLEDAFDSA-DALYLVLELMEGGELFNRVKQGALPEHNAKLIFYQLVLAVQARQPFRFPELAGLTIGGNVARVLRAFPCERPSRRASLPRQVSDFGLSRFVGEQYLMRSLCGTPAYQAPEVLASCGLGGYTRAVDCWSLGVLL</Hsp_qseq>
      <Hsp_hseq>GTVFEITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELK----LLKHLRHENLICLQDIFLSPLEDIYFVTEL-QGTDLHRLLQTRPLEKQFVQYFLYQI--------------LRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ--MTGYVSTRYYRAPEIMLTW--QKYDVEVDIWSAGCIF</Hsp_hseq>
      <Hsp_midline>GT   +  R+    P   G FG V  A    + + VAIK +  P     + + + R++K    +LK L+H  +I L+D F S  + +Y V EL +G +L   ++   L +   +   YQ+              L GL    +   + R           +   ++ DFGL+R    Q  M     T  Y+APE++ +     Y   VD WS G + </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>547535812</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058469-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.04 eAED:0.08 QI:0|0.83|0.85|1|0|0|7|4178|71</Iteration_query-def>
  <Iteration_query-len>4394</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>102</Statistics_hsp-len>
      <Statistics_eff-space>3052060854</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058470-RA transcript Note:&quot;Similar to PPAN Suppressor of SWI4 1 homolog (Pongo abelii)&quot; offset:0 AED:0.14 eAED:0.18 QI:0|0.66|0.8|1|0.33|0.4|10|0|136</Iteration_query-def>
  <Iteration_query-len>411</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YHR066W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:229335:230696:1 gene:YHR066W transcript:YHR066W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSF1 description:Constituent of 66S pre-ribosomal particles; required for ribosomal large subunit maturation; functionally redundant with Ssf2p; member of the Brix family; SSF1 has a paralog, SSF2, that arose from the whole genome duplication [Source:SGD;Acc:S000001108]</Hit_def>
  <Hit_accession>YHR066W</Hit_accession>
  <Hit_len>453</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>6.7044e-09</Hsp_evalue>
      <Hsp_query-from>94</Hsp_query-from>
      <Hsp_query-to>354</Hsp_query-to>
      <Hsp_hit-from>21</Hsp_hit-from>
      <Hsp_hit-to>147</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>127</Hsp_align-len>
      <Hsp_qseq>GVPHTLVFSRGTPS---HTLTQLVG-----------------RKNVLKDFVTVSGPLGITHFMIFSKTLDGINL-------------------YCLHRDVVSSIKRHR-MHEEQFTTPPLLVCNNLS</Hsp_qseq>
      <Hsp_hseq>GIPKSMVIRVGQTSLANHSLNQLVKDFRQIMQPHTAIKLKERKSNKLKDFVVMCGPLGVTHLFMFTQSEKTGNVSLKIARTPQGPTVTFQVLDYSLGRDIKKFLKRPKSLNNDDVLNPPLLVLNGFS</Hsp_hseq>
      <Hsp_midline>G+P ++V   G  S   H+L QLV                  + N LKDFV + GPLG+TH  +F+++    N+                   Y L RD+   +KR + ++ +    PPLLV N  S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YDR312W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1087581:1088942:1 gene:YDR312W transcript:YDR312W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSF2 description:Protein required for ribosomal large subunit maturation; functionally redundant with Ssf1p; member of the Brix family; SSF2 has a paralog, SSF1, that arose from the whole genome duplication [Source:SGD;Acc:S000002720]</Hit_def>
  <Hit_accession>YDR312W</Hit_accession>
  <Hit_len>453</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>1.477e-08</Hsp_evalue>
      <Hsp_query-from>136</Hsp_query-from>
      <Hsp_query-to>354</Hsp_query-to>
      <Hsp_hit-from>54</Hsp_hit-from>
      <Hsp_hit-to>147</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>46</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>94</Hsp_align-len>
      <Hsp_qseq>HTLTQLVGRK-NVLKDFVTVSGPLGITHFMIFSKTLDGINL-------------------YCLHRDVVSSIKRHR-MHEEQFTTPPLLVCNNLS</Hsp_qseq>
      <Hsp_hseq>HTAVKLKERKSNKLKDFVVMCGPLGVTHLFMFTQSEKTGNVSLKIARTPQGPTVTFQVLDYSLGRDIKKFLKRPKSLNNDDVLNPPLLVLNGFS</Hsp_hseq>
      <Hsp_midline>HT  +L  RK N LKDFV + GPLG+TH  +F+++    N+                   Y L RD+   +KR + ++ +    PPLLV N  S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>80</Statistics_hsp-len>
      <Statistics_eff-space>136005819</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058471-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.36 eAED:0.49 QI:0|0.54|0.66|1|0.45|0.5|12|0|160</Iteration_query-def>
  <Iteration_query-len>483</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>82</Statistics_hsp-len>
      <Statistics_eff-space>187456493</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058473-RA transcript Note:&quot;Similar to impad1 Inositol monophosphatase 3 (Xenopus laevis)&quot; offset:0 AED:0.11 eAED:0.11 QI:0|0.55|0.5|0.8|0.88|0.8|10|2719|631</Iteration_query-def>
  <Iteration_query-len>4615</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3206173145</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0043680-RA transcript Note:&quot;Similar to kctd6 BTB/POZ domain-containing protein KCTD6 (Danio rerio)&quot; offset:0 AED:0.33 eAED:0.34 QI:0|-1|0|1|-1|1|1|0|233</Iteration_query-def>
  <Iteration_query-len>702</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>87</Statistics_hsp-len>
      <Statistics_eff-space>343960449</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058474-RA transcript Note:&quot;Similar to LCK Proto-oncogene tyrosine-protein kinase LCK (Gallus gallus)&quot; offset:100 AED:0.06 eAED:0.06 QI:100|1|1|1|0.57|0.62|8|2109|401</Iteration_query-def>
  <Iteration_query-len>3415</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>89.7373</Hsp_bit-score>
      <Hsp_score>221</Hsp_score>
      <Hsp_evalue>1.60127e-18</Hsp_evalue>
      <Hsp_query-from>536</Hsp_query-from>
      <Hsp_query-to>1243</Hsp_query-to>
      <Hsp_hit-from>31</Hsp_hit-from>
      <Hsp_hit-to>262</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>122</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>245</Hsp_align-len>
      <Hsp_qseq>LGSGQFGEVWLALYKQ-NMKVAVKKL-REGSMSCEAFLGEANIMKTLRHERLVQLYAVV-SSEPILIITEYMEKGSMLDFLR------SEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEYTSKAGTKFPVRWTAPEAMHFGHFTTKSDVWSFGILLTEMITYGKIPYAGMSHQQLISNLDKGFRMPCPANCPSELYNQMLQCWNERAEERPT</Hsp_qseq>
      <Hsp_hseq>IGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLL-------GLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSALT-LAGT---LNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNP-PYHNLTDANIYYAVENDTYYP-PSSFSEPLKDFLSKCFVKNMYKRPT</Hsp_hseq>
      <Hsp_midline>+G G +G V+ A+ K  +  VA+K++  E        + E +++K L H  +V+ +  +  S  + I+ EY   GS+   +       SE   +  + + +L       G+ +L     +HRD++AAN+L+++    K+ADFG++ IV  +  T  AGT   + W APE +     +T SD+WS G  + EM+T    PY  ++   +   ++     P P++    L + + +C+ +   +RPT</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.4261</Hsp_bit-score>
      <Hsp_score>215</Hsp_score>
      <Hsp_evalue>5.78517e-18</Hsp_evalue>
      <Hsp_query-from>629</Hsp_query-from>
      <Hsp_query-to>1282</Hsp_query-to>
      <Hsp_hit-from>498</Hsp_hit-from>
      <Hsp_hit-to>716</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>226</Hsp_align-len>
      <Hsp_qseq>CEAFLGEANIMKTLRHERLVQLYAVVSSEPIL-IITEYMEKGSMLDFLRS----EEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVE--DNEYTSKAGTKFPVRWTAPEAMHFGHFTTKSDVWSFGILLTEMITYGKIPYAGMSHQQLISNLDKGFRMPCPANCPSELYNQMLQCWNERAEERPT-FEFLQDMLYDFHI</Hsp_qseq>
      <Hsp_hseq>VDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILI------GVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFT-GKHPFPDFSQMQAIFKIGTNTTPEIPSWATSEGKNFLRKAFELDYQYRPSALELLQHPWLDAHI</Hsp_hseq>
      <Hsp_midline> +A   E N++K L HE +V  Y        L I  EY+  GS+   L +    EE       R IL+      G+ +L K   +HRD++ AN+L++     K+ DFG+++ +   + +   +A  +  V W +PE +     T K+D+WS G ++ EM T GK P+   S  Q I  +        P+   SE  N + + +    + RP+  E LQ    D HI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.2705</Hsp_bit-score>
      <Hsp_score>212</Hsp_score>
      <Hsp_evalue>1.08184e-17</Hsp_evalue>
      <Hsp_query-from>527</Hsp_query-from>
      <Hsp_query-to>1255</Hsp_query-to>
      <Hsp_hit-from>363</Hsp_hit-from>
      <Hsp_hit-to>639</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>82</Hsp_identity>
      <Hsp_positive>125</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>282</Hsp_align-len>
      <Hsp_qseq>IEKLGSGQFGEVWLA----LYKQN--------------MKVAVKKLREGSM-SCEAFLGEANIMKTLRHERLVQLYA--VVSSEPILIITEYMEKGSMLDFL----RSEEGREVLIP----RLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEYTSKAGTKFPVR-WTAPEAMHFGHFTTKSDVWSFGILLTEMITYGKIPYAG---MSHQQLISNLDKGFRMPCPANCPSELYNQMLQCWNERAEERP------TFEFL</Hsp_qseq>
      <Hsp_hseq>VEKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQPKKQLIMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTG-EHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFC--VELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIE-GEPPYLNEDPLKALYLIAN-NGSPKLRHPESVSKQTKQFLDACLQVNVESRASVRKLLTFEFL</Hsp_hseq>
      <Hsp_midline>+EK G G  G V+L+    L ++N               +VA+K++R       +  + E  +M   R E +V      ++  E + +I EYME G + D L    RS  G E   P    ++  +  E   G+  L   + +HRD+++ N+L+NS    K+ DFG    VE  E  SK  T      W APE ++   +  K DVWS GI+L EMI  G+ PY     +    LI+N +   ++  P +   +    +  C     E R       TFEFL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.8853</Hsp_bit-score>
      <Hsp_score>211</Hsp_score>
      <Hsp_evalue>1.90059e-17</Hsp_evalue>
      <Hsp_query-from>425</Hsp_query-from>
      <Hsp_query-to>1108</Hsp_query-to>
      <Hsp_hit-from>527</Hsp_hit-from>
      <Hsp_hit-to>768</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>258</Hsp_align-len>
      <Hsp_qseq>AGLCQRLKKPCQSVTPAQPFEHNTWEIDRRDLKDIEKLGSGQFGEVWLA-----LYKQNM---------------KVAVKKLREGSMS-CEAFLGEANIMKTLRHERLVQLYAVV--SSEPILIITEYMEKGSMLDFLRSEEGRE-----VLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVED--NEYTSKAGTKFPVRWTAPEAMHFGHFTTKSDVWSFGILLTEMITYGKIPY</Hsp_qseq>
      <Hsp_hseq>AEIMSKLKKVTVNADPSQCF------------KVIEKAGQGASGSVYLAERTHIPTESNMIELINNDIDEPHVGDKVAIKQMVLSKQPRKELIVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPY---WMAPEVVKQREYDEKIDVWSLGIMTIEMLE-GEPPY</Hsp_hseq>
      <Hsp_midline>A +  +LKK   +  P+Q F            K IEK G G  G V+LA       + NM               KVA+K++        E  + E  +MK  RH+ +V        + + + ++ E+ME GS+ D + +    +     +  P++  +  E   G+  L     +HRD+++ NVL+++    K+ DFG    + D  ++  +  GT +   W APE +    +  K DVWS GI+  EM+  G+ PY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.6481</Hsp_bit-score>
      <Hsp_score>200</Hsp_score>
      <Hsp_evalue>4.43157e-17</Hsp_evalue>
      <Hsp_query-from>518</Hsp_query-from>
      <Hsp_query-to>1258</Hsp_query-to>
      <Hsp_hit-from>7</Hsp_hit-from>
      <Hsp_hit-to>256</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>133</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>263</Hsp_align-len>
      <Hsp_qseq>LKDIEKLGSGQFGEVWLALYKQN-MKVAVKKLR----EGSMSCEAFLGEANIMKTLRHERLVQLYAVVSSE-PILIITEYMEKGSMLDFLRSEEGREVL-IPRLILMAA------EVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRI--VEDNEYTSKAGTKFPVRWTAPEA-MHFGHFTTKSDVWSFGILLTEMITYGKIPYAGMSHQQLISNLDKGFRMPCPANCPSELYNQMLQCWNERAEERPTFEFLQ</Hsp_qseq>
      <Hsp_hseq>FKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTA--IREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDN----DLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLW---YRAPDVLMGSRTYSTSIDIWSCGCILAEMIT-GKPLFPGTNDEEQLKLIFDIMGTPNESLWPSV---TKLPKYNPNIQQRPPRDLRQ</Hsp_hseq>
      <Hsp_midline> K +EKLG+G +  V+  L K   + VA+K+++    EG+ S    + E ++MK L+HE +V+LY V+ +E  + ++ E+M+     D  +  + R V   PR + +        ++  G+    + + +HRDL+  N+L+N     K+ DFGL R   +  N ++S+  T +   + AP+  M    ++T  D+WS G +L EMIT GK  + G + ++ +  +      P  +  PS      L  +N   ++RP  +  Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.5741</Hsp_bit-score>
      <Hsp_score>205</Hsp_score>
      <Hsp_evalue>5.98881e-17</Hsp_evalue>
      <Hsp_query-from>503</Hsp_query-from>
      <Hsp_query-to>1114</Hsp_query-to>
      <Hsp_hit-from>186</Hsp_hit-from>
      <Hsp_hit-to>406</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>114</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>225</Hsp_align-len>
      <Hsp_qseq>IDRRDLKDIEKLGSGQFGEVWLALYKQNMKVAVKKL----REGSMSCEAFLGEANIMKTLR-HERLVQLYAVVSSE----PILIITEYMEKGSMLDFLR---------SEEGREVLIPRLIL--MAAEVADGMHHL-EKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEYTSKAGTKFPVRWTAPEAMHFGHFTTKSDVWSFGILLTEMITYGKIPYAG</Hsp_qseq>
      <Hsp_hseq>IQLQDLVQLGKIGAGNSGTVVKALHVPDSKIVAKKTIPVEQNNSTIINQLVRELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKLINSIADTFVGTS---TYMSPERIQGNVYSIKGDVWSLGLMIIELVT-GEFPLGG</Hsp_hseq>
      <Hsp_midline>I  +DL  + K+G+G  G V  AL+  + K+  KK     +  S      + E +I+K ++ HE ++  Y    ++     I+I+ EY + GS+   L          +   ++     L +  +A  V +G+ HL  + + +HRD++ +NVL+NS    K+ DFG+++ + ++   +  GT     + +PE +    ++ K DVWS G+++ E++T G+ P  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.6481</Hsp_bit-score>
      <Hsp_score>200</Hsp_score>
      <Hsp_evalue>1.05435e-16</Hsp_evalue>
      <Hsp_query-from>413</Hsp_query-from>
      <Hsp_query-to>1144</Hsp_query-to>
      <Hsp_hit-from>60</Hsp_hit-from>
      <Hsp_hit-to>295</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>250</Hsp_align-len>
      <Hsp_qseq>QSTDAGLCQRLKKPCQSVTPAQPFEHNTWEIDRRDLKDIEKLGSGQFGEVWLALYKQNMKV-AVKKLREGSM----SCEAFLGEANIMKTLRHERLVQLYAVV-SSEPILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEYTSKAGTKFPVRWTAPEAMHFGHFTTKSDVWSFGILLTEMITYGKIPYAGMSHQQLISNL</Hsp_qseq>
      <Hsp_hseq>EEASAGIC-LVKKPMLQ------YRDTSGKYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLR--KSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTL-CGTP---DYIAPEVVSTKPYNKSVDWWSFGVLIYEMLA-GYTPFYNSNTMKTYENI</Hsp_hseq>
      <Hsp_midline>+   AG+C  +KKP         +   + +    D + +  LG+G FG V L     N +  A+K L++ ++      E    E  ++  + H  +++++     S+ + ++ +Y+E G +   LR  + +    P     AAEV   + +L     ++RDL+  N+L++   + K+ DFG  + V D  YT   GT     + APE +    +    D WSFG+L+ EM+  G  P+   +  +   N+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.2629</Hsp_bit-score>
      <Hsp_score>199</Hsp_score>
      <Hsp_evalue>3.77123e-16</Hsp_evalue>
      <Hsp_query-from>527</Hsp_query-from>
      <Hsp_query-to>1165</Hsp_query-to>
      <Hsp_hit-from>58</Hsp_hit-from>
      <Hsp_hit-to>272</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>221</Hsp_align-len>
      <Hsp_qseq>IEKLGSGQFGEVWLALYKQN-MKVAVKKLREGSMSCEAFLG----EANIMKTLRHERLVQLYAVVSS-EPILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEYTSKAGTKFPVRWTAPEAMHFGHFT-TKSDVWSFGILLTEMITYGKIPYAGMSHQQLISNLDKG-FRMP</Hsp_qseq>
      <Hsp_hseq>VKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQ--QIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFL-KTSCGSP-NYAAPEVISGKLYAGPEVDVWSCGVILYVMLCR-RLPFDDESIPVLFKNISNGVYTLP</Hsp_hseq>
      <Hsp_midline>++ LG G FG+V LA +     KVA+K + +  ++     G    E + ++ LRH  +++LY V+ S + I+++ EY     + D++   +       R      ++   + +  + + VHRDL+  N+L++  LN K+ADFGL+ I+ D  +  K     P  + APE +    +   + DVWS G++L  M+   ++P+   S   L  N+  G + +P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.1073</Hsp_bit-score>
      <Hsp_score>196</Hsp_score>
      <Hsp_evalue>3.85029e-16</Hsp_evalue>
      <Hsp_query-from>512</Hsp_query-from>
      <Hsp_query-to>1108</Hsp_query-to>
      <Hsp_hit-from>85</Hsp_hit-from>
      <Hsp_hit-to>282</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>205</Hsp_align-len>
      <Hsp_qseq>RDLKDIEKLGSGQFGEVWLALYKQN-----MKVAVKKLREGSMSCEAFLGEANIMKTLRHERLVQLYAVV-SSEPILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEYTSKAGTKFPVRWTAPEAMHFGHFTTKSDVWSFGILLTEMITYGKIPY</Hsp_qseq>
      <Hsp_hseq>QDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLR--KSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTL-CGTP---DYIAPEVVSTKPYNKSIDWWSFGILIYEMLA-GYTPF</Hsp_hseq>
      <Hsp_midline>+D + +  LG+G FG V L   + N     MKV  K++       E    E  ++  + H  +++++     ++ I +I +Y+E G +   LR  + +    P     AAEV   + +L     ++RDL+  N+L++   + K+ DFG  + V D  YT   GT     + APE +    +    D WSFGIL+ EM+  G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.1814</Hsp_bit-score>
      <Hsp_score>191</Hsp_score>
      <Hsp_evalue>5.85105e-16</Hsp_evalue>
      <Hsp_query-from>521</Hsp_query-from>
      <Hsp_query-to>1195</Hsp_query-to>
      <Hsp_hit-from>9</Hsp_hit-from>
      <Hsp_hit-to>241</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>245</Hsp_align-len>
      <Hsp_qseq>KDIEKLGSGQFGEVWLAL----YKQNMKVAVKKLR---EGSMSCEAFLGEANIMKTLRHERLVQLYAVVSSEP--ILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVAD--------GMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRI--VEDNEYTSKAGTKFPVRWTAPEAMHFG-HFTTKSDVWSFGILLTEMITYGKIPYAGMSHQQLISNLDKGFRMPCPANCPSELY</Hsp_qseq>
      <Hsp_hseq>KRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLD----LDLKRYMEG----IPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLW---YRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPI-FSGDSEIDQIFKIFRVLGTPNEAIWPDIVY</Hsp_hseq>
      <Hsp_midline>K +EK+G G +G V+ AL     +    VA+KK+R   E        + E +++K L+ + +V+LY +V S+   + ++ E+++    LD  R  EG    IP+   + A++          G+ +    R +HRDL+  N+L+N   N K+ DFGL R   V    YT +  T +   + APE +  G  ++T  D WS G +  EM     I ++G S    I  + +    P  A  P  +Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.8777</Hsp_bit-score>
      <Hsp_score>198</Hsp_score>
      <Hsp_evalue>6.84998e-16</Hsp_evalue>
      <Hsp_query-from>533</Hsp_query-from>
      <Hsp_query-to>1108</Hsp_query-to>
      <Hsp_hit-from>625</Hsp_hit-from>
      <Hsp_hit-to>814</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>200</Hsp_align-len>
      <Hsp_qseq>KLGSGQFGEVWLAL-YKQNMKVAVKKLR-EGSMSCEAFLGEANIMKTLRHERLVQ-LYAVVSSEPILIITEYMEKGSMLDFLRS---EEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGL-TRIVEDN-EYTSKAGTKFPVRWTAPEAMHFGHFTTKSDVWSFGILLTEMITYGKIPY</Hsp_qseq>
      <Hsp_hseq>KIGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKELIINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVTHCILTEGQ------IGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTMVGTPY---WMAPEVVSRKEYGPKVDIWSLGIMIIEMI-EGEPPY</Hsp_hseq>
      <Hsp_midline>K+G G  G V+ A     N+ VA+K++  E     E  + E  +MK  +H  +V  + + V    + +I EYME GS+ D +      EG+      +  +  E   G+  L     +HRD+++ N+L++   + K+ DFG   +I E N + T+  GT +   W APE +    +  K D+WS GI++ EMI  G+ PY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.9518</Hsp_bit-score>
      <Hsp_score>193</Hsp_score>
      <Hsp_evalue>3.79744e-15</Hsp_evalue>
      <Hsp_query-from>530</Hsp_query-from>
      <Hsp_query-to>1243</Hsp_query-to>
      <Hsp_hit-from>1179</Hsp_hit-from>
      <Hsp_hit-to>1430</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>120</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>257</Hsp_align-len>
      <Hsp_qseq>EKLGSGQFGEVWLALYKQNMKV-AVKKLR--------EGSMSC-EAFLGEANIMKTLRHERLVQLYAVVSSEPIL-IITEYMEKGSMLDFLRSEEGR--EVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEYTSKAGTKFPVRWTAPEAMHFGH-FTTKSDVWSFGILLTEMITYGKIPYAGMSHQQLISNLDKGFRMPCPANCPSELYNQMLQ-----CWNERAEERPT</Hsp_qseq>
      <Hsp_hseq>EMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMY-GRFDEPLIKHL---TTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFA-GKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPT</Hsp_hseq>
      <Hsp_midline>E +G G FG V+L L     ++ AVK++         E  +S  EA   E + +K L H  +VQ     +   I  +  EY+  GS+   +R   GR  E LI  L     +V  G+ +L     +HRD++A N+L++    CK++DFG++R  +D    S    +  V W APE +     ++ K D+WS G ++ EM   GK P++ +     +  + K    P        L +Q+ +     C+    E+RPT</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.3294</Hsp_bit-score>
      <Hsp_score>181</Hsp_score>
      <Hsp_evalue>2.8949e-14</Hsp_evalue>
      <Hsp_query-from>497</Hsp_query-from>
      <Hsp_query-to>1123</Hsp_query-to>
      <Hsp_hit-from>17</Hsp_hit-from>
      <Hsp_hit-to>222</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>216</Hsp_align-len>
      <Hsp_qseq>WEIDRRDLKDIEKLGSGQFGEVWLALYK-QNMKVAVKKLRE---GSMSCEAFLGEANIMKTLRHERLVQLYAVVSS--EPILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEYTSKAGTKFPVRWTAPEAM-HFGHFTTKSDVWSFGILLTEMITYGKIPYAGMSH</Hsp_qseq>
      <Hsp_hseq>FEITNR-YNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLSPLEDIYFVTEL--QGTDLHRLLQTRPLEKQFVQYFLY--QILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARI-QDPQMTGYVSTRY---YRAPEIMLTWQKYDVEVDIWSAGCIFAEMIE-GKPLFPGKDH</Hsp_hseq>
      <Hsp_midline>+EI  R   D+  +G G FG V  A     +  VA+KK+ +    ++  +    E  ++K LRHE L+ L  +  S  E I  +TE   +G+ L  L      E    +  L   ++  G+ ++     +HRDL+ +N+L+N   + K+ DFGL RI +D + T    T++   + APE M  +  +  + D+WS G +  EMI  GK  + G  H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.7146</Hsp_bit-score>
      <Hsp_score>182</Hsp_score>
      <Hsp_evalue>3.57715e-14</Hsp_evalue>
      <Hsp_query-from>536</Hsp_query-from>
      <Hsp_query-to>1264</Hsp_query-to>
      <Hsp_hit-from>24</Hsp_hit-from>
      <Hsp_hit-to>275</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>119</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>258</Hsp_align-len>
      <Hsp_qseq>LGSGQFGEVWLAL---YKQNMKVAVKKLREGSMSCEAFLGEANIMKTLRHERLVQLYAVVSSE-PILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDN-EYTSKAGTKFPVRWTAPEAM--HFGHFTTKSDVWSFGILLTEMITYGKIPYAGMSHQQLISNLDKGFRMPCPANCP-SELYNQMLQ-CWNERAEERP------TFEFLQDM</Hsp_qseq>
      <Hsp_hseq>IGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRDTFVGTPY---WMAPEVVCCEVDGYNEKADIWSLGITTYELLK-GLPPLSKYDPMKVMTNLPK--RKPPKLQGPFSDAAKDFVAGCLVKTPADRPSAYNLLSFEFVKNI</Hsp_hseq>
      <Hsp_midline>+G G FG+V+ A+    ++ + + V  L       E    E   +  L+   +    A +  +  + I+ EY   GS  D L+      +   ++  +  EV  G+ +L + R +HRD++AAN+L+N     K+ DFG++  +    +  +  GT +   W APE +      +  K+D+WS GI   E++  G  P +     ++++NL K  R P     P S+     +  C  +   +RP      +FEF++++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.0998</Hsp_bit-score>
      <Hsp_score>183</Hsp_score>
      <Hsp_evalue>3.79695e-14</Hsp_evalue>
      <Hsp_query-from>536</Hsp_query-from>
      <Hsp_query-to>1114</Hsp_query-to>
      <Hsp_hit-from>88</Hsp_hit-from>
      <Hsp_hit-to>283</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>202</Hsp_align-len>
      <Hsp_qseq>LGSGQFGEVWLALYKQNMKVAVKKLREGSMSCEA----FLGEANIMKTLRHERLVQLYAVVSSEP-ILIITEYMEKGSMLDFLRSEEGREVLI-PRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEYTSKAGTKFPVRWTAPEAM---HFGHFTTKSDVWSFGILLTEMITYGKIPYAG</Hsp_qseq>
      <Hsp_hseq>LGEGGFARCFQIKDDSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKR---RKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLA-NESERKYTICGTPNYIAPEVLMGKHSGH-SFEVDIWSLGVMLYALLI-GKPPFQA</Hsp_hseq>
      <Hsp_midline>LG G F   +          A K + + S+  E      L E  I K++ H  +VQ       +  + I+ E    GS+++ L+    R+VL  P +     ++   + ++   R +HRDL+  N+  +S  N K+ DFGL  ++  NE   K        + APE +   H GH + + D+WS G++L  ++  GK P+  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>1.52939e-13</Hsp_evalue>
      <Hsp_query-from>515</Hsp_query-from>
      <Hsp_query-to>1108</Hsp_query-to>
      <Hsp_hit-from>69</Hsp_hit-from>
      <Hsp_hit-to>265</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>204</Hsp_align-len>
      <Hsp_qseq>DLKDIEKLGSGQFGEVWLALYKQNMKV-AVKKLREGSM----SCEAFLGEANIMKTLRHERLVQLYAVV-SSEPILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEYTSKAGTKFPVRWTAPEAMHFGHFTTKSDVWSFGILLTEMITYGKIPY</Hsp_qseq>
      <Hsp_hseq>DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLR--KSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTL-CGTP---DYIAPEVITTKPYNKSVDWWSLGVLIYEMLA-GYTPF</Hsp_hseq>
      <Hsp_midline>D + +  LG+G FG V L     N +  A+K L++  +      E    E  ++K + H  L++++     +  I ++ +Y+E G +   LR  + +    P     AAEV   + +L     ++RDL+  N+L++   + K+ DFG  + V+   +T   GT     + APE +    +    D WS G+L+ EM+  G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.4034</Hsp_bit-score>
      <Hsp_score>176</Hsp_score>
      <Hsp_evalue>2.39357e-13</Hsp_evalue>
      <Hsp_query-from>515</Hsp_query-from>
      <Hsp_query-to>1261</Hsp_query-to>
      <Hsp_hit-from>359</Hsp_hit-from>
      <Hsp_hit-to>619</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>121</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>267</Hsp_align-len>
      <Hsp_qseq>DLKDIEKLGSGQFGEVWLALYK-QNMKVAVKKLRE--GSMSCEAFLGEANIMKTLRHERLVQLYAVVSSE-PILIITEYMEKGSMLD-FLRSEEGREVLIPRLILMAAEVADGMHHL-EKMRYVHRDLRAANVLVNS-LLNCKVADFGLTRIVEDNEYTSKAGTKFPVR-WTAPEAMHF-----GHFTTKSDVWSFGILLTEMITYGKIPYAGMSHQQLISNLDKGFRMPCPANCPSELYNQMLQ-----CWNERAEERPTFEFLQD</Hsp_qseq>
      <Hsp_hseq>ELEFLDELGHGNYGNVSKVLHKPTNVIMATKEVRLELDEAKFRQILMELEVLHKCNSPYIVDFYGAFFIEGAVYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSANQGTVKLCDFG----VSGNLVASLAKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEM-ALGRYPYPPETYDNIFSQLSAIVDGP-PPRLPSDKFSSDAQDFVSLCLQKIPERRPTYAALTE</Hsp_hseq>
      <Hsp_midline>+L+ +++LG G +G V   L+K  N+ +A K++R           L E  ++       +V  Y     E  + +  EYM+ GS+   +  S E   +  P+L  +A  V  G+  L E+   +HRD++  N+L ++     K+ DFG    V  N   S A T    + + APE +         +T +SD+WS G+ + EM   G+ PY   ++  + S L      P P   PS+ ++   Q     C  +  E RPT+  L +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.2478</Hsp_bit-score>
      <Hsp_score>173</Hsp_score>
      <Hsp_evalue>5.94705e-13</Hsp_evalue>
      <Hsp_query-from>476</Hsp_query-from>
      <Hsp_query-to>1108</Hsp_query-to>
      <Hsp_hit-from>332</Hsp_hit-from>
      <Hsp_hit-to>542</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>219</Hsp_align-len>
      <Hsp_qseq>QPFEHNTWEIDRRDLKDIEKLGSGQFGEVWLALYKQNMKV-AVKKLREGSM--SCEAF--LGEANIMKTLRHERLVQL-YAVVSSEPILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRI-VEDNEYTSK-AGTKFPVRWTAPEAMHFGHFTTKSDVWSFGILLTEMITYGKIPY</Hsp_qseq>
      <Hsp_hseq>KPSKNKPLSIDDFDL--LKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQ-HEGRFSLA-RSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTP---EYLAPEILLGQGYTKTVDWWTLGILLYEMMT-GLPPY</Hsp_hseq>
      <Hsp_midline>+P ++    ID  DL  ++ +G G FG+V     K   K+ A+K LR+  +   CE    L E  ++  +    +V L ++  S E + ++  ++  G +   L+  EGR  L  R     AE+   +  L K+  ++RDL+  N+L++   +  + DFGL ++ ++DN+ T    GT     + APE +    +T   D W+ GILL EM+T G  PY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.8626</Hsp_bit-score>
      <Hsp_score>172</Hsp_score>
      <Hsp_evalue>9.29478e-13</Hsp_evalue>
      <Hsp_query-from>500</Hsp_query-from>
      <Hsp_query-to>1108</Hsp_query-to>
      <Hsp_hit-from>16</Hsp_hit-from>
      <Hsp_hit-to>220</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>212</Hsp_align-len>
      <Hsp_qseq>EIDRRDL-KDIEKLGSGQFGEVWLALYKQNMKV-AVK--KLREGSMSCEAFLGEANIMKTLRHERLVQLY--AVVSSEPILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEY--TSKAGTKFPVRWTAPEAMHFG-HFTTKSDVWSFGILLTEMITYGKIPY</Hsp_qseq>
      <Hsp_hseq>EMDVSSLFKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLRPGKIDEKYI---GVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPY---WMAPEVIMEGVYYDTKVDIWSLGITTYEIAT-GNPPY</Hsp_hseq>
      <Hsp_midline>E+D   L K  E +G G+FG V+     +  +V A+K   L   S   E    E   + +L+    +  Y  + +    + II E+   GS+   LR  +  E  I    ++  E+   +  + K   +HRD++AANVL+ +  N K+ DFG+   V        + AGT +   W APE +  G ++ TK D+WS GI   E+ T G  PY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>1.99876e-12</Hsp_evalue>
      <Hsp_query-from>530</Hsp_query-from>
      <Hsp_query-to>1165</Hsp_query-to>
      <Hsp_hit-from>25</Hsp_hit-from>
      <Hsp_hit-to>249</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>237</Hsp_align-len>
      <Hsp_qseq>EKLGSGQFGEVWLALYKQN-MKVAVKKLRE------GSMSCEAFLGEANI------MKTLRHERLVQLYAV-VSSEPILIITEYMEKGSMLDFLRSE----EGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNE-YTSKAGTKFPVRWTAPE---AMHFGHFTTKSDVWSFGILLTEMITYGKIPY--AGMSHQQLISNLDKG-FRMP</Hsp_qseq>
      <Hsp_hseq>ETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIII------GISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSP---HYAAPEIVSGLPYEGFA--SDVWSCGVILFALLT-GRLPFDEENGNVRDLLLKVQKGQFEMP</Hsp_hseq>
      <Hsp_midline>E LG G  G+V LA +++   + AVK + +      G+ S +  +   NI      MK L H  ++ LY V  ++  + +I EY EKG + + L       E   +   R I++      G+ +   +  VHRDL+  N+L++S  N K+ADFG+  +  D +   +  G+     + APE    + +  F   SDVWS G++L  ++T G++P+     + + L+  + KG F MP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>2.0056e-12</Hsp_evalue>
      <Hsp_query-from>458</Hsp_query-from>
      <Hsp_query-to>1144</Hsp_query-to>
      <Hsp_hit-from>199</Hsp_hit-from>
      <Hsp_hit-to>431</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>243</Hsp_align-len>
      <Hsp_qseq>QSVTPAQPFEHNTWEIDRRDLKD-IEKLG---SGQFGEVWLALYKQNMKV----AVKKLREGSMSCEAFLGEANIMKTLRHERLVQLYAVVSSE---PILIITEYMEKGSMLDFLRS---EEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEYTSKAGTKFPVRWTAPEAMHFGHFTTKSDVWSFGILLTEMITYGKIPYAGMSHQQLISNL</Hsp_qseq>
      <Hsp_hseq>NSVRDVDQLDENGWKY--ANLKDRIETLGILGEGAGGSVSKCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQFNRSFQSEYIVRYYGMFTDDENSSIYIAMEYM-GGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVSGEAVNSLATTFTGTSF---YMAPERIQGQPYSVTSDVWSLGLTILE-VANGKFP---CSSEKMAANI</Hsp_hseq>
      <Hsp_midline> SV      + N W+    +LKD IE LG    G  G V     K   K+     +  L       +    E    ++ + E +V+ Y + + +    I I  EYM  G  LD +     E G  +    L  +A  V  G+ +L + + +HRD++  N+L+N     K+ DFG++    ++  T+  GT F   + APE +    ++  SDVWS G+ + E +  GK P    S +++ +N+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>3.39114e-12</Hsp_evalue>
      <Hsp_query-from>521</Hsp_query-from>
      <Hsp_query-to>1132</Hsp_query-to>
      <Hsp_hit-from>14</Hsp_hit-from>
      <Hsp_hit-to>235</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>223</Hsp_align-len>
      <Hsp_qseq>KDIEKLGSGQFGEVWLALYKQN-MKVAVKKLREGS--MSCEAFLGEANIMKTL-RHERLVQLYAVVSS------EPILIITEYMEKGSMLDFLRSEEGREVLIPRLI-LMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEYTSKAGTKF-----PVRW-TAPEAM-HFGHFTTKSDVWSFGILLTEMITYGKIPYAGMS-HQQL</Hsp_qseq>
      <Hsp_hseq>KLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVS-GKPLFPGRDYHHQL</Hsp_hseq>
      <Hsp_midline>K ++ +G G +G V  A++K + +KVA+KK++  S  +     + E  +++    HE ++ +   V          + ++ E ME            G   L    +     ++   +  +   + +HRD++ +N+L+NS  + KV DFGL R +  +  + +    F       RW  APE M  F  +TT  D+WS G +L EM++ GK  + G   H QL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>8.35509e-12</Hsp_evalue>
      <Hsp_query-from>503</Hsp_query-from>
      <Hsp_query-to>1165</Hsp_query-to>
      <Hsp_hit-from>319</Hsp_hit-from>
      <Hsp_hit-to>562</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>248</Hsp_align-len>
      <Hsp_qseq>IDRRDLKDIEKLGSGQFGEVWLALYKQNMKV-AVKKLREGSM----SCEAFLGEANIMKTLRHERLVQLYAVVSSEPIL-IITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGL-------------------TRIVEDNEYT-SKAGTKFPVRWTAPEAMHFGHFTTKSDVWSFGILLTEMITYGKIPYAGMSHQQLISN-LDKGFRMP</Hsp_qseq>
      <Hsp_hseq>VEPQSFEKIRLLGQGDVGKVYLVRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTE---EYLAPEVIRGNGHTAAVDWWTLGILIYEML-FGCTPFKGDNSNETFSNILTKDVKFP</Hsp_hseq>
      <Hsp_midline>++ +  + I  LG G  G+V+L   +   ++ A+K L +  M      +  L E  I+ T  H  +V LY    ++  L +  EY   G     L++ + + +        A+EV   + +L  + +++RDL+  N+L++   +  ++DF L                   T+I  D   T S  GT+    + APE +     T   D W+ GIL+ EM+ +G  P+ G +  +  SN L K  + P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.3958</Hsp_bit-score>
      <Hsp_score>163</Hsp_score>
      <Hsp_evalue>9.38921e-12</Hsp_evalue>
      <Hsp_query-from>476</Hsp_query-from>
      <Hsp_query-to>1108</Hsp_query-to>
      <Hsp_hit-from>335</Hsp_hit-from>
      <Hsp_hit-to>545</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>219</Hsp_align-len>
      <Hsp_qseq>QPFEHNTWEIDRRDLKDIEKLGSGQFGEVWLALYKQNMKV-AVKKLREGSMSCEA----FLGEANIMKTLRHERLVQL-YAVVSSEPILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRI--VEDNEYTSKAGTKFPVRWTAPEAMHFGHFTTKSDVWSFGILLTEMITYGKIPY</Hsp_qseq>
      <Hsp_hseq>KPSRNKPLSIDDFDL--LKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQ-KEGRFDL-SRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTP---EYLAPELLLGLGYTKAVDWWTLGVLLYEMLT-GLPPY</Hsp_hseq>
      <Hsp_midline>+P  +    ID  DL  ++ +G G FG+V     K   KV A+K +R+  +  ++     L E  ++  +    +V L ++  S E +  +  ++  G +   L+ +EGR  L  R     AE+   + +L K+  V+RDL+  N+L++   +  + DFGL ++   +D++  +  GT     + APE +    +T   D W+ G+LL EM+T G  PY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>1.20382e-11</Hsp_evalue>
      <Hsp_query-from>512</Hsp_query-from>
      <Hsp_query-to>1153</Hsp_query-to>
      <Hsp_hit-from>410</Hsp_hit-from>
      <Hsp_hit-to>627</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>RDLKDIEKLGSGQFGEVWLALYKQN-----MKVAVKKLREGSMSCEAFLGEANIMKTLRHER---LVQL-YAVVSSEPILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEYTSKAGTKFPVRWTAPE-AMHFGHFTTKSDVWSFGILLTEMITYGKIPYAGMSHQQLISNLDKG</Hsp_qseq>
      <Hsp_hseq>QDFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQ-KEGR-FSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGT---TEYLAPELLLDETGYTKMVDFWSLGVLIFEMCC-GWSPFFAENNQKMYQKIAFG</Hsp_hseq>
      <Hsp_midline>+D + +  LG G FG+V+    K       MKV  KK+          +GE NI+ T   +    +V L ++  +   + ++T+YM  G +   L+ +EGR     R     AE+   + HL     V+RDL+  N+L+++  N  + DFGL++    +   +  GT     + APE  +    +T   D WS G+L+ EM   G  P+   ++Q++   +  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>1.34233e-11</Hsp_evalue>
      <Hsp_query-from>530</Hsp_query-from>
      <Hsp_query-to>1153</Hsp_query-to>
      <Hsp_hit-from>202</Hsp_hit-from>
      <Hsp_hit-to>423</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>234</Hsp_align-len>
      <Hsp_qseq>EKLGSGQFGEVWLALYKQNMKVAVKKL---REGSMSCEAFLGEANIMKTLRHERLVQLYAVV-SSEPILIITEYMEKGSMLDFLRS------EEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLV--NSLLNCKVADFGLTRIVEDNEYTSK-AGTKFPVRWTAPEAMHF-------------GHFTTKSDVWSFGILLTEMITYGKIPYAGMSHQQLISNLDKG</Hsp_qseq>
      <Hsp_hseq>EVVGQGAFATVKKAIERTTGKTFAVKIISKRKVIGNMDGVTRELEVLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGRE--ISRQILTA------IKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMKTFCGT---LAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILT-GHLPFSGSTQDQLYKQIGRG</Hsp_hseq>
      <Hsp_midline>E +G G F  V  A+ +   K    K+   R+   + +    E  +++ L H R+V+L      +E   ++ E++  G ++DF+ +      + GRE  I R IL A      + ++  M   HRDL+  N+L+  +  +  K+ DFGL ++  +  +     GT   + + APE +                 +++  D+WS G L+  ++T G +P++G +  QL   + +G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>1.38944e-11</Hsp_evalue>
      <Hsp_query-from>536</Hsp_query-from>
      <Hsp_query-to>1108</Hsp_query-to>
      <Hsp_hit-from>220</Hsp_hit-from>
      <Hsp_hit-to>415</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>200</Hsp_align-len>
      <Hsp_qseq>LGSGQFGEVWLALYKQNMKV-AVKKLREGSMSCE---AFLGEANIMKTLRHERLVQLYAVVSSE---PILIITEYMEKGSMLDFLRSEEGREVLIPRLIL--MAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEYTSKAGTKFPVRWTAPEAMHFGHFTTKSDVWSFGILLTEMITYGKIPY</Hsp_qseq>
      <Hsp_hseq>LGEGAGGSVAKCRLKNGKKVFALKTINTMNTDPEYQKQIFRELQFNKSFKSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFGVSGEAVNSLAMTFTGTSF---YMAPERIQGQPYSVTCDVWSLGLTLLE-VAGGRFPF</Hsp_hseq>
      <Hsp_midline>LG G  G V     K   KV A+K +   +   E       E    K+ + + +VQ Y + + E    I I  EYM   S+    ++   R   I   ++  +A  V  G+ +L + + +HRD++  N+L+N     K+ DFG++    ++   +  GT F   + APE +    ++   DVWS G+ L E +  G+ P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>1.40209e-11</Hsp_evalue>
      <Hsp_query-from>536</Hsp_query-from>
      <Hsp_query-to>1135</Hsp_query-to>
      <Hsp_hit-from>19</Hsp_hit-from>
      <Hsp_hit-to>234</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>220</Hsp_align-len>
      <Hsp_qseq>LGSGQFGEVWLALYKQNMK-VAVKKLREGSMSCEAF--LGEANIMKTLRHERLVQLYAVVSSEP------ILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEYTSKAGTK--------FPVRW-TAPEAM-HFGHFTTKSDVWSFGILLTEMITYGKI-PYAGMSHQQLI</Hsp_qseq>
      <Hsp_hseq>LGEGAYGVVCSATHKPTGEIVAIKKIEPFDKPLFALRTLREIKILKHFKHENIITIFNIQRPDSFENFNEVYIIQELMQT----DLHRVISTQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLL</Hsp_hseq>
      <Hsp_midline>LG G +G V  A +K   + VA+KK+        A   L E  I+K  +HE ++ ++ +   +       + II E M+     D  R    + +    +     +    +  L     +HRDL+ +N+L+NS  + KV DFGL RI++++   +   T            RW  APE M     ++   DVWS G +L E+     I P     HQ L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>1.79212e-11</Hsp_evalue>
      <Hsp_query-from>530</Hsp_query-from>
      <Hsp_query-to>1159</Hsp_query-to>
      <Hsp_hit-from>11</Hsp_hit-from>
      <Hsp_hit-to>219</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>225</Hsp_align-len>
      <Hsp_qseq>EKLGSGQFGEVWLAL-YKQNMKVAVKKLREGSMSCE---AFLGEANIMKTLRHERLVQLYAVVSSEPILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVAD-------GMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNE--YTSKAGTKFPVRWTAPEAMHFG--HFTTKSDVWSFGILLTEMITYGKIPYAGMSHQQLISNLDKGFR</Hsp_qseq>
      <Hsp_hseq>KKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNVIEL--------IDIFMAYDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNVVTRW---YRAPELL-FGAKHYTSAIDIWSVGVIFAELML--RIPY--LPGQNDVDQMEVTFR</Hsp_hseq>
      <Hsp_midline>+K+G G +  V+L   +    K+A+K+++          + + E   ++ ++H  +++L        I I   Y     +L+FL ++    +    ++   A++         G++H  +   +HRDL+  N+L +     KVADFGL R +       TS   T++   + APE + FG  H+T+  D+WS G++  E++   +IPY  +  Q  +  ++  FR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>2.40535e-11</Hsp_evalue>
      <Hsp_query-from>536</Hsp_query-from>
      <Hsp_query-to>1108</Hsp_query-to>
      <Hsp_hit-from>52</Hsp_hit-from>
      <Hsp_hit-to>252</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>103</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>207</Hsp_align-len>
      <Hsp_qseq>LGSGQFGEVWLALYKQN------MKVAVKKLREGSMSCEA-----FLGEANIMKTLRHERLVQLYAVV-SSEPILIITEYMEKGSMLDFL-RSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFG-LTRIVEDNEYTSKAGTKFPVRWTAPEAM--HFGHFTTKSDVWSFGILLTEMITYGKIPY</Hsp_qseq>
      <Hsp_hseq>LGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLF---AQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELM-KTSCGSPC-YAAPELVVSTKAYEARKADVWSCGVILYAMLA-GYLPW</Hsp_hseq>
      <Hsp_midline>LG G+FG+V L   K +       +VA+K +R  ++  +A        E N +K L H  ++ L  V+ +S+ I I+ E++  G    ++ R    +E    RL    A++  G++++     VHRDL+  N+L++   N  + DFG +    EDNE   K     P  + APE +     +   K+DVWS G++L  M+  G +P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>2.62025e-11</Hsp_evalue>
      <Hsp_query-from>512</Hsp_query-from>
      <Hsp_query-to>1144</Hsp_query-to>
      <Hsp_hit-from>494</Hsp_hit-from>
      <Hsp_hit-to>729</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>240</Hsp_align-len>
      <Hsp_qseq>RDLKDIEKLGSGQFGEVWLALYKQNMKV-AVKKLREGSM----SCEAFLGEANIMKTLRHERLVQLYAVVSSEPILII-TEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGL----------------------TRIVEDNEYTSK-AGTKFPVRWTAPEAMHFGHFTTKSDVWSFGILLTEMITYGKIPYAGMSHQQLISNL</Hsp_qseq>
      <Hsp_hseq>QSFEKIRLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTE---EYIAPEVIRGNGHTAAVDWWTLGILIYEML-FGFTPFKGDNTNETFTNI</Hsp_hseq>
      <Hsp_midline>+  + I  LG G  G+V+L   K+  +V A+K L +  M      +  L E  I+ T  H  +V LY    SE  L +  EY   G     L++ + + +        A+EV   + +L  + +++RDL+  N+L++   +  ++DF L                      T+I  D   T+   GT+    + APE +     T   D W+ GIL+ EM+ +G  P+ G +  +  +N+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>3.54502e-11</Hsp_evalue>
      <Hsp_query-from>521</Hsp_query-from>
      <Hsp_query-to>1087</Hsp_query-to>
      <Hsp_hit-from>61</Hsp_hit-from>
      <Hsp_hit-to>277</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>KDIEKLGSGQFGEVWLALYKQNMK-VAVKKLREGSMSCEAFL------GEANIMKTLRHERLVQLYAVV---SSEPILIITEYMEKG--SMLDFLRSEEGREVLIPRLIL-------MAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEYTSKAGTKFP--------------VRW-TAPE-AMHFGHFTTKSDVWSFGILLTEMI</Hsp_qseq>
      <Hsp_hseq>REDEKLGQGTFGEVYKGIHLETQRQVAMKKI---IVSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLY----YGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFF</Hsp_hseq>
      <Hsp_midline>++ EKLG G FGEV+  ++ +  + VA+KK+    +S E  L       E  I+K L H+ +++L  +V   S +     +  + K    +L ++ ++    +  PR+ L       M  ++ +G++++   +++HRD++ AN+L++     K+ADFGL R+     Y      K+P               RW  APE  +    +TT  D+W  G +  E  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.4698</Hsp_bit-score>
      <Hsp_score>158</Hsp_score>
      <Hsp_evalue>4.23995e-11</Hsp_evalue>
      <Hsp_query-from>500</Hsp_query-from>
      <Hsp_query-to>1153</Hsp_query-to>
      <Hsp_hit-from>90</Hsp_hit-from>
      <Hsp_hit-to>338</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>55</Hsp_gaps>
      <Hsp_align-len>261</Hsp_align-len>
      <Hsp_qseq>EIDRRDLKD---IEKLGSGQFGEVWLALYKQNMKVAV-------------------------------KKLREGSMSCEAFLGEANIMKTLRHERLVQLYAVVS-SEPILIITEYMEKGSMLDF------LRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVE-DNEYTSKAGTKFPVRWTAPEAMHFGHFT-TKSDVWSFGILLTEMITYGKIPYAGMSHQQLISNLDKG</Hsp_qseq>
      <Hsp_hseq>QFHRRSLGDWEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESEILERQKRLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARK--------FARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYRKQLHTFCGSLY---FAAPELLKAQPYTGPEVDIWSFGIVLYVLVC-GKVPFDDENSSILHEKIKKG</Hsp_hseq>
      <Hsp_midline>+  RR L D   +E +G+G  G+V L  ++Q  ++ V                               K+L +     +  + EA++ + L H  + +L+ + + S    ++ EY+  G +LD+      L+    R+         A  +A  + +L     VHRDL+  N++++S    K+ DFGL+ I +   +  +  G+ +   + APE +    +T  + D+WSFGI+L  ++  GK+P+   +   L   + KG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>5.99431e-11</Hsp_evalue>
      <Hsp_query-from>530</Hsp_query-from>
      <Hsp_query-to>1168</Hsp_query-to>
      <Hsp_hit-from>23</Hsp_hit-from>
      <Hsp_hit-to>254</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>242</Hsp_align-len>
      <Hsp_qseq>EKLGSGQFGEVWLALY-KQNMKVAVKKLRE-----GSMSCEAFLG-------------EANIMKTLRHERLVQLYAV-VSSEPILIITEYMEKGSMLDFLRSEEGREVLIPR--LILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRI-VEDNEYTSKAGTKFPVRWTAPE---AMHFGHFTTKSDVWSFGILLTEMITYGKIPY--AGMSHQQLISNLDKG-FRMPC</Hsp_qseq>
      <Hsp_hseq>ETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLL-VERG---PLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALETEGKLLETSCGSPH---YAAPEIVSGIPYQGFA--SDVWSCGVILFALLT-GRLPFDEEDGNIRTLLLKVQKGEFEMPS</Hsp_hseq>
      <Hsp_midline>E LG G  G+V LA       + AVK + +     G++S  + +G             E  IMK L H  +++LY V  ++  + ++ EY EKG + + L  E G    +P    I    ++  G+ +   +  VHRDL+  N+L++   N K+ADFG+  +  E     +  G+     + APE    + +  F   SDVWS G++L  ++T G++P+     + + L+  + KG F MP </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>6.46591e-11</Hsp_evalue>
      <Hsp_query-from>536</Hsp_query-from>
      <Hsp_query-to>1177</Hsp_query-to>
      <Hsp_hit-from>1040</Hsp_hit-from>
      <Hsp_hit-to>1275</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>242</Hsp_align-len>
      <Hsp_qseq>LGSGQFGEVWLALYKQNMKV-AVK--KLREGSMSCEAF---LGEANIMKTLRHERLVQLYAV-VSSEPILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRI------------------VEDNEYTSKAGTKFPVRWTAPEAMHFGHFTTK---SDVWSFGILLTEMITYGKIPYAGMSHQQLISNLDKGFRMPCPAN</Hsp_qseq>
      <Hsp_hseq>IGGGTFGQVYSAINLENGEILAVKEIKIHDTTTMKKIFPLIKEEMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEYCEGGSLASLLDHGRIEDEMVTQVYTF--ELLEGLAYLHQSGVVHRDIKPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPM---YMAPETISGSAVKGKLGADDVWALGCVVLEMAT-GRRPWSNLDNEWAIMYHVAAGRIPQLPN</Hsp_hseq>
      <Hsp_midline>+G G FG+V+ A+  +N ++ AVK  K+ + +   + F     E  +++ L H  +VQ Y V V  + + I  EY E GS+   L      + ++ ++     E+ +G+ +L +   VHRD++  N+L++     K  DFG  R                   VE        GT     + APE +       K    DVW+ G ++ EM T G+ P++ + ++  I       R+P   N</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>1.76234e-10</Hsp_evalue>
      <Hsp_query-from>527</Hsp_query-from>
      <Hsp_query-to>1186</Hsp_query-to>
      <Hsp_hit-from>186</Hsp_hit-from>
      <Hsp_hit-to>407</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>231</Hsp_align-len>
      <Hsp_qseq>IEKLGSGQFGEVWLALYKQNMK-VAVKKLR-EGSMSCEAF----LGEANIMKTLRHERL--VQLYAVVSSEPILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDN-EYTSKAGTKFPVRWTAPEAMHFG--HFTTKSDVWSFGILLTEMITYGKIPYAGMSHQQLISNLDKGFRMPCPANCPS</Hsp_qseq>
      <Hsp_hseq>IMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGER--EGFPITSIREIKLLQSFDHPNVSTIKEIMVESQKTVYMIFEYADND--LSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKMNSRADYTNRVIT----LWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAI-FQGSNELEQIESIFKIMGTPTINSWPT</Hsp_hseq>
      <Hsp_midline>I ++G G +G+V+ A      K VA+KKLR +G    E F    + E  ++++  H  +  ++   V S + + +I EY +    L  L   +  ++   +   +  ++  GM +L   + +HRD++ +N+L+++  N K+ DFGL R +    +YT++  T     W  P  +  G  ++ T+ D+W  G LL E+     I + G +  + I ++ K    P   + P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>2.21252e-10</Hsp_evalue>
      <Hsp_query-from>461</Hsp_query-from>
      <Hsp_query-to>1165</Hsp_query-to>
      <Hsp_hit-from>105</Hsp_hit-from>
      <Hsp_hit-to>381</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>280</Hsp_align-len>
      <Hsp_qseq>SVTPAQPFEHNTWE--IDR--RDLKDIEKLGSGQFGEVWLALYKQNMKV-AVKKLREG------------------------------SMSCEAFLGEANIMKTLRHERLVQL-YAVVSSEPILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTR-----IVEDNEYTSKAGTKFPV----RWTAPEAMHFGHFTTKSDVWSFGILLTEMITYGKIPYAGMSHQQLISNLDKGFRMP</Hsp_qseq>
      <Hsp_hseq>SITPQDIISSNIGENELSRNLHDFKPVRVLGQGAYGKVLLVKDVNTSKLYAMKQLRKAEILISQTATDSKREDEDKNDGNNNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGEL--FYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLV-GKPPYTGSNHKVIINKIQQNKQGP</Hsp_hseq>
      <Hsp_midline>S+TP      N  E  + R   D K +  LG G +G+V L       K+ A+K+LR+                               S   E    E +I+  + H  +V+L Y+   +  + ++ +Y+  G +  F   +E   +    +   AAE++  +  L     V+RDL+  N L+N   +  + DFGL++        D E        + +     + APE +    ++   D +S G LL +M+  GK PY G +H+ +I+ + +  + P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>2.2351e-10</Hsp_evalue>
      <Hsp_query-from>515</Hsp_query-from>
      <Hsp_query-to>1087</Hsp_query-to>
      <Hsp_hit-from>1095</Hsp_hit-from>
      <Hsp_hit-to>1298</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>211</Hsp_align-len>
      <Hsp_qseq>DLKDIEKLGSGQFGEVWLALYKQNMKVAVKKL------------REGSMSCEAFLGEANIMKTLR---HERLVQLYAVVSSEPILIITE--YMEKG--SMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEYTSKAGTKFPVRWTAPEAMHFGHFTTK-SDVWSFGILLTEMI</Hsp_qseq>
      <Hsp_hseq>DFVSLQKMGEGAYGKVNLCIHKKNRYIVVIKMIFKERILVDTWVRDRKLGT--IPSEIQIMATLNKKPHENILRLLDFFEDDDYYYIETPVHGETGCIDLFDLIEFKTNMTEFEAKLIF--KQVVAGIKHLHDQGIVHRDIKDENVIVDSKGFVKIIDFGSAAYVKSGPFDVFVGT---IDYAAPEVLGGNPYEGQPQDIWAIGILLYTVV</Hsp_hseq>
      <Hsp_midline>D   ++K+G G +G+V L ++K+N  + V K+            R+  +       E  IM TL    HE +++L      +    I    + E G   + D +  +        +LI    +V  G+ HL     VHRD++  NV+V+S    K+ DFG    V+   +    GT   + + APE +    +  +  D+W+ GILL  ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>3.78069e-10</Hsp_evalue>
      <Hsp_query-from>527</Hsp_query-from>
      <Hsp_query-to>1093</Hsp_query-to>
      <Hsp_hit-from>41</Hsp_hit-from>
      <Hsp_hit-to>281</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>60</Hsp_gaps>
      <Hsp_align-len>245</Hsp_align-len>
      <Hsp_qseq>IEKLGSGQFGEVWLALYKQNMKVAVKKLRE--GSMSCEAFLGEAN--------------------------------IMKTLRHERLVQLYAV-VSSE--PILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLN-----------------CKVADFGLTRIVED-NEYTSKAGTKFPVRWTAPEA-MHFGHFTTKSDVWSFGILLTEMITY</Hsp_qseq>
      <Hsp_hseq>IEKLGAGSFGCVTLAKAQFPLSNILGKQHDIRGTLMDQPKNGHQNYITKTQGVVAIKTMMTKLHTLQDYTRVREIKFILAIPANDHLIQIFEVFIDSENYQLHIVMECMEQ-NLYQMMKHRRRRVFSIPSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVENKNPYTAYVSTRW---YRSPEILLRSGYYSKPLDIWAFGCVAVEVTVF</Hsp_hseq>
      <Hsp_midline>IEKLG+G FG V LA  +  +   + K  +  G++  +   G  N                                I+    ++ L+Q++ V + SE   + I+ E ME+ ++   ++    R   IP L  + +++  G+ H+ +  + HRDL+  N+L+                       K+ADFGL R VE+ N YT+   T++   + +PE  +  G+++   D+W+FG +  E+  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>4.14606e-10</Hsp_evalue>
      <Hsp_query-from>497</Hsp_query-from>
      <Hsp_query-to>1123</Hsp_query-to>
      <Hsp_hit-from>17</Hsp_hit-from>
      <Hsp_hit-to>238</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>226</Hsp_align-len>
      <Hsp_qseq>WEIDRRDLKDIEKLGSGQFGEVWLALYKQ---NMKVAVKKLR---EGSMSCEAFLGEANIMKTLR-HERLVQLYAVV------SSEPILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEY-TSKAGTKF-PVRW-TAPEAM-HFGHFTTKSDVWSFGILLTEMITYGKIPYAGMSH</Hsp_qseq>
      <Hsp_hseq>FSVDKR-FQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKS--GQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLG-GKPIFKGKDY</Hsp_hseq>
      <Hsp_midline>+ +D+R  + I+++G G +G V  A + +   +  VA+KK+      ++ C+  L E  +++  R H+ +  LY +        S   L + E + +  M   ++S  G+ +          ++  G+ ++     +HRDL+  N+LVN+    K+ DFGL R   +N    S+  T++   RW  APE M  +  +T   DVWS G +L E +  GK  + G  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.6178</Hsp_bit-score>
      <Hsp_score>148</Hsp_score>
      <Hsp_evalue>5.74965e-10</Hsp_evalue>
      <Hsp_query-from>512</Hsp_query-from>
      <Hsp_query-to>1108</Hsp_query-to>
      <Hsp_hit-from>123</Hsp_hit-from>
      <Hsp_hit-to>337</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>RDLKDIEKLGSGQFGEVWLALYKQN-MKVAVKKLREGSMSCEAFLGEANIMKTLRHERLV-----------QLYAVVSSEPIL-IITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEYTSKAGTKF------------PVRWTAPEAMHFGHFTTKSDVWSFGILLTEMITYGKIPY</Hsp_qseq>
      <Hsp_hseq>KDFKFGEQLGDGSYSSVVLATARDSGKKYAVKVL------SKEYLIRQKKVKYVTVEKLALQKLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARY--YASQIIDAVDSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLA-GKPPF</Hsp_hseq>
      <Hsp_midline>+D K  E+LG G +  V LA  + +  K AVK L       + +L     +K +  E+L            +L+     E  L  + EY   G  L  ++          R    A+++ D +  L  +  +HRD++  N+L++  +  K+ DFG  +I+ +    +  G  +               + +PE ++  +  ++ D+W+FG +L +M+  GK P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>1.14094e-09</Hsp_evalue>
      <Hsp_query-from>536</Hsp_query-from>
      <Hsp_query-to>1135</Hsp_query-to>
      <Hsp_hit-from>1272</Hsp_hit-from>
      <Hsp_hit-to>1509</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>243</Hsp_align-len>
      <Hsp_qseq>LGSGQFGEVWLALYKQNMKV-AVKKLR-EGSMSCEAFLG----EANIMKTLRHERLVQLYAV-VSSEPILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGL--------TRIVEDNEYTSKAGTKFPVR-----------------------WTAPEAMHFGHFTTK-----SDVWSFGILLTEMITYGKIPYAGMSHQQLI</Hsp_qseq>
      <Hsp_hseq>IGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAALLEHGRIEDEMVTQVYTL--QLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGS--TTKGKLGADDVWSLGCVVLEMIT-GRRPWANLDNEWAI</Hsp_hseq>
      <Hsp_midline>+G G FG V+ A+   N ++ AVK++  + S S +        E ++++ L H  +V  Y V V  + + I  EY E GS+   L      + ++ ++  +  ++ +G+ +L +   VHRD++  N+L++     K  DFG         TR+   N+  +  G    V                        + APE++     TTK      DVWS G ++ EMIT G+ P+A + ++  I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>1.14734e-09</Hsp_evalue>
      <Hsp_query-from>536</Hsp_query-from>
      <Hsp_query-to>1114</Hsp_query-to>
      <Hsp_hit-from>830</Hsp_hit-from>
      <Hsp_hit-to>1026</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>204</Hsp_align-len>
      <Hsp_qseq>LGSGQFGEVWLALYKQNMKV-AVKKLREGSM----SCEAFLGEANIM---KTLRHERLVQLYAVVSSEP-ILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTR--IVEDNEYTSKAGTKFPVRWTAPEAMHFGHFTTKSDVWSFGILLTEMITYGKIPYAG</Hsp_qseq>
      <Hsp_hseq>LGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGG---DLMWHVQNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTP---EFMAPEILKEQEYTKAVDWWAFGVLLYQML-LCQSPFSG</Hsp_hseq>
      <Hsp_midline>LG G FG+V L+  K   ++ A+K L++ ++      E+   E  +       +H  L  LY    +E  I    E++  G   D +   + + + + R    AAEV   + +      ++RDL+  N+L+    + K+AD+GL +  +   N  ++  GT     + APE +    +T   D W+FG+LL +M+   + P++G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>1.15097e-09</Hsp_evalue>
      <Hsp_query-from>509</Hsp_query-from>
      <Hsp_query-to>1108</Hsp_query-to>
      <Hsp_hit-from>114</Hsp_hit-from>
      <Hsp_hit-to>344</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>55</Hsp_gaps>
      <Hsp_align-len>243</Hsp_align-len>
      <Hsp_qseq>RRDLKD---IEKLGSGQFGEVWLALYKQNMKVAV-------------------------------KKLREGSMSCEAFLGEANIMKTLRHERLVQLYAVVS-SEPILIITEYMEKGSMLDFL------RSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVED-NEYTSKAGTKFPVRWTAPEAMHFGHFT-TKSDVWSFGILLTEMITYGKIPY</Hsp_qseq>
      <Hsp_hseq>RKSLGDWEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPPPKNEQDVLERQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIREHQARK--------FARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIYDSRKQLHTFCGSLY---FAAPELLKANPYTGPEVDVWSFGVVLFVLVC-GKVPF</Hsp_hseq>
      <Hsp_midline>R+ L D   +E +G+G  G+V LA ++   +V                                 KKL +     +  + EA++ + L H  + +L+ + + S    ++ EY+  G +LD++      R  + R+         A  +A  + +L     VHRDL+  N++++     K+ DFGL+ I +   +  +  G+ +   + APE +    +T  + DVWSFG++L  ++  GK+P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YPR111W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:747306:749000:1 gene:YPR111W transcript:YPR111W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF20 description:Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006315]</Hit_def>
  <Hit_accession>YPR111W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>1.34702e-09</Hsp_evalue>
      <Hsp_query-from>512</Hsp_query-from>
      <Hsp_query-to>1165</Hsp_query-to>
      <Hsp_hit-from>167</Hsp_hit-from>
      <Hsp_hit-to>429</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>73</Hsp_gaps>
      <Hsp_align-len>277</Hsp_align-len>
      <Hsp_qseq>RDLKDIEKLGSGQFGEVWLALYKQN-----MKVAVKKLREGSMSCEAFLGEANIMKTLRHERLVQL-YAVVSSEPILIITEYMEKGSMLDFLRSEEGREVLIPRLILMA-------AEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEYTSKAGTKFPVRWTAPEAMHFGHFTTKS-------------------------------------------DVWSFGILLTEMITYGKIPYAGMSHQQLISNL---DKGFRMP</Hsp_qseq>
      <Hsp_hseq>KDFQILTQVGQGGYGQVYLAKKKDSDEICALKILNKKLLFKLNETNHVLTERDILTTTRSDWLVKLLYAFQDPESLYLAMEFVPGG---DF------RTLLINTRILKSGHARFYISEMFCAVNALHELGYTHRDLKPENFLIDATGHIKLTDFGLAAGTVSNERIE----SMKIRLEEVKNLEFPAFTERSIEDRRKIYHNMRKTEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLV-GYTPFSGSSTNETYENLRYWKKTLRRP</Hsp_hseq>
      <Hsp_midline>+D + + ++G G +G+V+LA  K +     +K+  KKL          L E +I+ T R + LV+L YA    E + +  E++  G   DF      R +LI   IL +       +E+   ++ L ++ Y HRDL+  N L+++  + K+ DFGL      NE          +R    + + F  FT +S                                           D WS G +L E +  G  P++G S  +   NL    K  R P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>1.4194e-09</Hsp_evalue>
      <Hsp_query-from>536</Hsp_query-from>
      <Hsp_query-to>1108</Hsp_query-to>
      <Hsp_hit-from>47</Hsp_hit-from>
      <Hsp_hit-to>252</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>216</Hsp_align-len>
      <Hsp_qseq>LGSGQFGEVWLALYKQ-----------NMKVAVKKLREGSMSCE-----AFLGEANIMKTLRHERLVQLYAVV-SSEPILIITEYMEKGSMLDFLRSEEG-REVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEYTS-----KAGTKFPVRWTAPEAMHFG--HFTTKSDVWSFGILLTEMITYGKIPY</Hsp_qseq>
      <Hsp_hseq>LGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRKEVKIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLF---SQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFV-----NEFCSRNELMKTSCGSPC-YAAPELVISAEPYEARKADIWSCGVILYAILA-GYLPW</Hsp_hseq>
      <Hsp_midline>LG G+FG+V L   K              +VA+K ++  S+S +         E N +K L H  +V+L  V+ +S  I I+ EY   G    +++ +   +E+   RL    +++  G+H++     VHRDL+  N+L++   N  + DFG       NE+ S     K     P  + APE +     +   K+D+WS G++L  ++  G +P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>1.44538e-09</Hsp_evalue>
      <Hsp_query-from>512</Hsp_query-from>
      <Hsp_query-to>1144</Hsp_query-to>
      <Hsp_hit-from>175</Hsp_hit-from>
      <Hsp_hit-to>427</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>56</Hsp_gaps>
      <Hsp_align-len>260</Hsp_align-len>
      <Hsp_qseq>RDLKDIEKLGSGQFGEVWLALYKQN-----MKVAVKKLREGSMSCEAFLGEANIMKTLRHERLVQL-YAVVSSEPILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEYTSKAGTKFPVRWTAPEAMHFGHFTTKS-------------------------------------------DVWSFGILLTEMITYGKIPYAGMSHQQLISNL</Hsp_qseq>
      <Hsp_hseq>RDFEMITQVGQGGYGQVYLARKKDTKEVCALKILNKKLLFKLNETKHVLTERDILTTTRSEWLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINTRCLKSGHARFYI--SEMFCAVNALHDLGYTHRDLKPENFLIDAKGHIKLTDFGLAAGTISNERIE----SMKIRLEKIKDLEFPAFTEKSIEDRRKMYNQLREKEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLV-GYTPFSGSSTNETYDNL</Hsp_hseq>
      <Hsp_midline>RD + I ++G G +G+V+LA  K       +K+  KKL       +  L E +I+ T R E LV+L YA    + + +  E++  G     L +    +    R  +  +E+   ++ L  + Y HRDL+  N L+++  + K+ DFGL      NE          +R    + + F  FT KS                                           D WS G +L E +  G  P++G S  +   NL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>1.4913e-09</Hsp_evalue>
      <Hsp_query-from>521</Hsp_query-from>
      <Hsp_query-to>1108</Hsp_query-to>
      <Hsp_hit-from>42</Hsp_hit-from>
      <Hsp_hit-to>232</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>205</Hsp_align-len>
      <Hsp_qseq>KDIEKLGSGQFGEVWLALYKQNMKVAVKKLREGSMSCEAFLGEANIMKTLRHER------LVQLYAVVSSEP-ILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTR-IVEDNEYTSKAGTKFPVRWTAPEAMHFGHFTT-KSDVWSFGILLTEMITYGKIPY</Hsp_qseq>
      <Hsp_hseq>KILKQIGEGSFGKVYLALHRPTHRKVCLKTSDKN--------DPNIVREVFYHRQFDFPYITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLL--ECGELFAQISGAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTRECMTKTTLETVCGTTV---YMAPELIERRTYDGFKIDIWSLGVILYTLIT-GYLPF</Hsp_hseq>
      <Hsp_midline>K ++++G G FG+V+LAL++   +    K  + +        + NI++ + + R      + +LY V+ +E  + +  EY     + D L S     +L      + A+++  +++   M  VHRDL+  N+L++   N K+ DFG TR  +      +  GT     + APE +    +   K D+WS G++L  +IT G +P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>2.34166e-09</Hsp_evalue>
      <Hsp_query-from>536</Hsp_query-from>
      <Hsp_query-to>1165</Hsp_query-to>
      <Hsp_hit-from>56</Hsp_hit-from>
      <Hsp_hit-to>296</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>55</Hsp_gaps>
      <Hsp_align-len>253</Hsp_align-len>
      <Hsp_qseq>LGSGQFGEVWLAL-YKQNMKVAVKKL-----REG-----SMSCEAFLGEANIMKTLRHERLVQLYAVVS---SEPILIITEYMEKG-----------------SMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGL--------TRIVEDNEYTSKAGTKFPVRWTAPEAMHF-GHFTTKS--DVWSFGILLTEMITYGKIPYAGMSHQQLI-SNLDKGFRMP</Hsp_qseq>
      <Hsp_hseq>LGNGQYGKVKLARDLGTGALVAIKILNRFEKRSGYSLQLKVENPRVNQEIEVMKRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAVGPSILTF---QQSRKVVL--------DVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLL-FGKLPFNANSGLELFDSIINKPLEFP</Hsp_hseq>
      <Hsp_midline>LG+GQ+G+V LA        VA+K L     R G      +       E  +MK   HE +V+LY +++   S  + ++ EY  +G                 S+L F   ++ R+V++        +V  G+ +L      HRD++ +N+L++S    K++DFG+        T I   +E   K+       + APE       ++  S  D+WS G+ +  ++ +GK+P+   S  +L  S ++K    P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.3066</Hsp_bit-score>
      <Hsp_score>142</Hsp_score>
      <Hsp_evalue>2.37257e-09</Hsp_evalue>
      <Hsp_query-from>662</Hsp_query-from>
      <Hsp_query-to>1108</Hsp_query-to>
      <Hsp_hit-from>71</Hsp_hit-from>
      <Hsp_hit-to>222</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>159</Hsp_align-len>
      <Hsp_qseq>KTLRHERLVQLYAV-VSSEPILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEYTSKAGT-------KFPVRWTAPEAMHF--GHFTTKSDVWSFGILLTEMITYGKIPY</Hsp_qseq>
      <Hsp_hseq>KCSKHPNVLRLIDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVE-CGVAHRDIKPENILLDKNGNLKLADFGLA-----SQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLT-GQTPW</Hsp_hseq>
      <Hsp_midline>K  +H  +++L    VS E + II E  + G + D +  + G +  + +        A    H+E     HRD++  N+L++   N K+ADFGL      +++  K GT       +    + APE ++   G++  ++D+WS GILL  ++T G+ P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>3.08793e-09</Hsp_evalue>
      <Hsp_query-from>518</Hsp_query-from>
      <Hsp_query-to>1114</Hsp_query-to>
      <Hsp_hit-from>35</Hsp_hit-from>
      <Hsp_hit-to>242</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>215</Hsp_align-len>
      <Hsp_qseq>LKDIEKLGSGQFGEVWLALYKQNMK-----VAVKKLREGSMSCEAFLGEANIMKTLRHERLVQLYAVVS--SEPILIITEYMEKGSMLDFLRSEEGR------EVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNC-KVADFGLTRIVEDNEYT-SKAGTKFPVRWTAPE-AMHFGHFTTKSDVWSFGILLTEMITYGKIPYAG</Hsp_qseq>
      <Hsp_hseq>VKEYRKIGRGAFGTVVQAYLTQDKKNWLGPFAIKKV---PAHTEYKSRELQILRIADHPNIVKLQYFFTHLSPQDNKVYQHLAMECLPETLQIEINRYVTNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSISYICSRF---YRAPELIIGCTQYTTQIDIWGLGCVMGEMLI-GKAIFQG</Hsp_hseq>
      <Hsp_midline>+K+  K+G G FG V  A   Q+ K      A+KK+       E    E  I++   H  +V+L    +  S     + +++    + + L+ E  R      E+ +  + L   ++A GM +L  +   HRD++ +NVLV+      K+ DFG  + +E N+ + S   ++F   + APE  +    +TT+ D+W  G ++ EM+  GK  + G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>3.5272e-09</Hsp_evalue>
      <Hsp_query-from>632</Hsp_query-from>
      <Hsp_query-to>1108</Hsp_query-to>
      <Hsp_hit-from>147</Hsp_hit-from>
      <Hsp_hit-to>301</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>162</Hsp_align-len>
      <Hsp_qseq>EAFLGEANIMKTLRHERLVQLYAVVSSEP-ILIITEYMEKGSMLDFLRSEEG-REVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRI-VEDNEYTSKAGTKFPVRWTAPEAMHFGHFTTKSDVWSFGILLTEMITYGKIPY</Hsp_qseq>
      <Hsp_hseq>KQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMH---KKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTVCGT---IDYLSPEMVESREYDHTIDAWALGVLAFELLT-GAPPF</Hsp_hseq>
      <Hsp_midline>+ F  E  I  +L H  L + Y     E  + ++ EY+  G M   LR      ++L    I   A   D MH   K   +HRD++  N+L+      K+ DFG + I   +N   +  GT   + + +PE +    +    D W+ G+L  E++T G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>4.5282e-09</Hsp_evalue>
      <Hsp_query-from>512</Hsp_query-from>
      <Hsp_query-to>1114</Hsp_query-to>
      <Hsp_hit-from>177</Hsp_hit-from>
      <Hsp_hit-to>391</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>218</Hsp_align-len>
      <Hsp_qseq>RDLKDIEKLGSGQFGEVWLALYKQNMK-VAVKKLREGSMSCEAFLGEANIMKTLRHE-----RLVQLYAVVSSEPIL-IITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVE-DNEYTSKAGTKFPVR---------WTAPEAMHFGHFTTKSDVWSFGILLTEMITYGKIPYAG</Hsp_qseq>
      <Hsp_hseq>KDFKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARY--YAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIA-GKPPFKA</Hsp_hseq>
      <Hsp_midline>+D K    +G G +  V LA      K  A K L +  +  +  +   +I KT   +      +V+L++    E  L  + EY   G  L  ++     +    R    AA++ D + +L     +HRD++  N+L++  +  K+ DFG  +++   N   SK       R         + +PE ++      + D+W+FG +L +MI  GK P+  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>6.24775e-09</Hsp_evalue>
      <Hsp_query-from>530</Hsp_query-from>
      <Hsp_query-to>1075</Hsp_query-to>
      <Hsp_hit-from>204</Hsp_hit-from>
      <Hsp_hit-to>411</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>220</Hsp_align-len>
      <Hsp_qseq>EKLGSGQFGEVWLALYKQN-MKVAVK----KLREGSMSCEAFLGEANIMKTLRHERLVQLYAVVSSEPI-------LIITEYMEKGSMLD------FLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSL-------------------LNCKVADFGLTRIVEDNEYTSK-AGTKFPVRWTAPEAMHFGHFTTKSDVWSFGILL</Hsp_qseq>
      <Hsp_hseq>KELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFV-EPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALF--------KQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTP---SYVAPEVLTKKGYTSKVDLWSAGVIL</Hsp_hseq>
      <Hsp_midline>++LG+G +  V  A  K+   +VAVK    +  +     + F  E NI+  ++H  +V L      EPI        ++ E ++ G + +       LR +E + +          ++  G+ +L +   +HRD++  N+L+N                     +  K+ADFGL +   + ++T+   GT     + APE +    +T+K D+WS G++L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>2.52138e-08</Hsp_evalue>
      <Hsp_query-from>515</Hsp_query-from>
      <Hsp_query-to>1249</Hsp_query-to>
      <Hsp_hit-from>840</Hsp_hit-from>
      <Hsp_hit-to>1091</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>114</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>261</Hsp_align-len>
      <Hsp_qseq>DLKDIEKLGSGQFGEVWLALY-KQNMKVAVKKLREGSMSCEAFL---------GEANIMKTLR---HERLVQLYAVVSSEPILIITE--YMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEYTSKAGTKFPVRWTAPEAMHFGHFTTK-SDVWSFGILLTEMITYGKIPYAGMSHQQLISNLDKGFRMPCPANCPSELYNQMLQCWNERAEERPTFE</Hsp_qseq>
      <Hsp_hseq>DFTILQVMGEGAYGKVNLCIHNREHYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKNSQENILKLLDFFEDDDYYYIETPVHGETGSIDLFDVIEFKKDMVEHEAKLVFKQVVASIKHLHDQGIVHRDIKDENVIVDSHGFVKLIDFGSAAYIKSGPFDVFVGT---MDYAAPEVLGGSSYKGKPQDIWALGVLLYTII-YKENPYYNIDEI-----LEGELRFDKSEHVSEECISLIKRILTREVDKRPTID</Hsp_hseq>
      <Hsp_midline>D   ++ +G G +G+V L ++ +++  V +K + +  +  + ++          E  IM TL     E +++L      +    I    + E GS+  F   E  ++++     L+  +V   + HL     VHRD++  NV+V+S    K+ DFG    ++   +    GT   + + APE +    +  K  D+W+ G+LL  +I Y + PY  +        L+   R     +   E  + + +      ++RPT +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>3.50494e-08</Hsp_evalue>
      <Hsp_query-from>536</Hsp_query-from>
      <Hsp_query-to>1261</Hsp_query-to>
      <Hsp_hit-from>43</Hsp_hit-from>
      <Hsp_hit-to>296</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>114</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>261</Hsp_align-len>
      <Hsp_qseq>LGSGQFGEVWLALYKQN-----MKVAVKKLREGS-MSCEAFLGEANIMKTLRHERLVQLYA-VVSSEPILIITEYMEKGSMLD-FLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLV---NSLLNCKVADFGLT-RIVEDNEYTSK-AGTKFPVRWTAPEAMHFGHFTTKSDVWSFGILLTEMITYGKIPYAGMSHQQLISNLDKG-----FRMPCPANCPSELYNQMLQCWNERAEERPT-FEFLQD</Hsp_qseq>
      <Hsp_hseq>LGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILV---EILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGS---LGYVAPEVLTQDGHGKPCDIWSIGV-ITYTLLCGYSAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAELLED</Hsp_hseq>
      <Hsp_midline>LG+G FG V  A   +      +K+ +KK  +G+ +  EA   E +I++ L H  +V       S +   IIT+  + G + D  L+  +  E    R+++   E+   + ++     VHRDL+  N+L    +      VADFG+  R+  D E   K AG+   + + APE +         D+WS G+ +T  +  G   +     Q  +     G     F  P   +  ++    +L+  N    +RPT  E L+D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>1.07903e-07</Hsp_evalue>
      <Hsp_query-from>656</Hsp_query-from>
      <Hsp_query-to>1168</Hsp_query-to>
      <Hsp_hit-from>167</Hsp_hit-from>
      <Hsp_hit-to>336</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>13</Hsp_gaps>
      <Hsp_align-len>177</Hsp_align-len>
      <Hsp_qseq>IMKTLRHERLVQLYAVVSSEPIL-IITEYMEKGSMLDFLRSEEGREVLIPR--LILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSL-LNCKVADFGLTRIVEDNEYTSKAGTKFPVRWTAPE-AMHFGHFTTKSDVWSFGILLTEMITYGKIPYAGMSHQQLISNLDKG-FRMPC</Hsp_qseq>
      <Hsp_hseq>IMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSK-GK---LPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLL-KTSCGSP-HYASPEIVMGRPYHGGPSDVWSCGIVLFALLT-GHLPFNDDNIKKLLLKVQSGKYQMPS</Hsp_hseq>
      <Hsp_midline>IMK + H  ++ L+ V  ++  L ++ EY++ G + D+L S+ G+   +P    I    ++ +G+ +       HRDL+  N+L++      K+ADFG+  +   N+   K     P  + +PE  M   +    SDVWS GI+L  ++T G +P+   + ++L+  +  G ++MP </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>1.31512e-07</Hsp_evalue>
      <Hsp_query-from>524</Hsp_query-from>
      <Hsp_query-to>1138</Hsp_query-to>
      <Hsp_hit-from>446</Hsp_hit-from>
      <Hsp_hit-to>664</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>223</Hsp_align-len>
      <Hsp_qseq>DIEKLGSGQFGEVWLALYKQ-NMKVAVKKLREGSM-SCEAFLGEANIMK------TLRHERLVQLYAVVSS----EPILIITEYMEKGSMLDFLRSE---EGREVLIPRLILMAAEVADGMHHL-EKMRYVHRDLRAANVLVNSLLNCKVADFGLTR--IVEDNEYTSKAGTKFPVRWTAPEAMHFGHFTTKSDVWSFGILLTEMITYGKIPYAGMSHQQLIS</Hsp_qseq>
      <Hsp_hseq>NVHSIGKGQFSTVYQVTFAQTNKKYAIKAIKPNKYNSLKRILLEIKILNEVTNQITMDQEGKEYIIDYISSWKFQNSYYIMTELCENGNLDGFLQEQVIAKKKRLEDWRIWKIIVELSLALRFIHDSCHIVHLDLKPANVMITFEGNLKLGDFGMATHLPLEDKSFENEGDREY----IAPEIISDCTYDYKADIFSLGLMIVEIAANVVLPDNGNAWHKLRS</Hsp_hseq>
      <Hsp_midline>++  +G GQF  V+   + Q N K A+K ++     S +  L E  I+       T+  E    +   +SS        I+TE  E G++  FL+ +   + + +   R+  +  E++  +  + +    VH DL+ ANV++    N K+ DFG+     +ED  + ++   ++     APE +    +  K+D++S G+++ E+     +P  G +  +L S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YNL020C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:595623:597539:-1 gene:YNL020C transcript:YNL020C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ARK1 description:Serine/threonine protein kinase; involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis; ARK1 has a paralog, PRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004965]</Hit_def>
  <Hit_accession>YNL020C</Hit_accession>
  <Hit_len>638</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>1.32446e-07</Hsp_evalue>
      <Hsp_query-from>527</Hsp_query-from>
      <Hsp_query-to>1093</Hsp_query-to>
      <Hsp_hit-from>25</Hsp_hit-from>
      <Hsp_hit-to>242</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>219</Hsp_align-len>
      <Hsp_qseq>IEKLGSGQFGEVWLALYK-----QNMKVAVKK--LREGSMSCEAFLGEANIMKTLRHERLVQLY-------AVV--SSEPILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADG---MHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLT-------RIVEDNEYTSKAGTK-FPVRWTAPEAMHFGH---FTTKSDVWSFGILLTEMITY</Hsp_qseq>
      <Hsp_hseq>IKYLTSGGFAQVYSALINPPDPHSNSSVACLKRVIVPDKPSLNTLRAEVDAMRLLKNNRYVVSYIDSHAAKAMLHNGSYEVFVLMEYCERGGLIDFMNTRLQNRLHEFEILQIMSQVTQGVAAMHALQP-PLIHRDIKIENVLISANNEYKLCDFGSVCGIIRPPRNSQELSYVQQDILKNTTAQYRSPEMIDTFRGLPIDEKSDIWALGIFLYKLCYY</Hsp_hseq>
      <Hsp_midline>I+ L SG F +V+ AL        N  VA  K  +     S      E + M+ L++ R V  Y       A++   S  + ++ EY E+G ++DF+ +     +    ++ + ++V  G   MH L+    +HRD++  NVL+++    K+ DFG         R  ++  Y  +   K    ++ +PE +          KSD+W+ GI L ++  Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>1.68312e-07</Hsp_evalue>
      <Hsp_query-from>521</Hsp_query-from>
      <Hsp_query-to>1075</Hsp_query-to>
      <Hsp_hit-from>193</Hsp_hit-from>
      <Hsp_hit-to>435</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>76</Hsp_gaps>
      <Hsp_align-len>252</Hsp_align-len>
      <Hsp_qseq>KDIEKLGSGQFGEVWL-ALYKQN----MKVAVKKLR-----------EGSMSCEAFLG--------EANIMKTLRHERLVQLYA------VVSSEPIL--------------IITEYMEKGSMLDFLRSEEGR--EVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLV-----------NSLLNCK-----VADFGLTRIVEDNEY-TSKAGTKFPVRWTAPEAM----HFGHFTTKSDVWSFGILL</Hsp_qseq>
      <Hsp_hseq>KKVRPIGSGNFSTVLLYELMDQSNPKLKQVAVKRLKYPEELSNVEQINTSLRYKETLSRLENSLTRELQVLKSLNHPCIVKLLGINNPIFVTSKKPLCDLIIKTPRALPPCDMIMSYCPAGDLLAAVMARNGRLEAWLIQRIF---TEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLCKKIENNEMCTARCGSE---DYVSPEILMGVPYDGHL---SDTWALGVIL</Hsp_hseq>
      <Hsp_midline>K +  +GSG F  V L  L  Q+     +VAVK+L+             S+  +  L         E  ++K+L H  +V+L        V S +P+               +I  Y   G +L  + +  GR    LI R+     EV   + +L +   +HRDL+  N+L+           +S + CK     +ADFGL + +E+NE  T++ G++    + +PE +    + GH    SD W+ G++L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>1.89869e-07</Hsp_evalue>
      <Hsp_query-from>536</Hsp_query-from>
      <Hsp_query-to>1261</Hsp_query-to>
      <Hsp_hit-from>53</Hsp_hit-from>
      <Hsp_hit-to>306</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>261</Hsp_align-len>
      <Hsp_qseq>LGSGQFGEVWLAL-YKQNMKVAVK-----KLREGSMSCEAFLGEANIMKTLRHERLVQLYA-VVSSEPILIITEYMEKGSMLD-FLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVL-VNSLLNCK--VADFGLTRIV--EDNEYTSKAGTKFPVRWTAPEAMHFGHFTTKSDVWSFGILLTEMITYGKIPYAGMSHQQLI-----SNLDKGFRMPCPANCPSELYNQMLQCWNERAEERPT-FEFLQD</Hsp_qseq>
      <Hsp_hseq>LGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMH---SKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGS---LGYVAPEVLTQDGHGKPCDIWSIGV-ITYTLLCGYSPFIAESVEGFMEECTASRYPVTFHMPYWDNISIDVKRFILKALRLNPADRPTATELLDD</Hsp_hseq>
      <Hsp_midline>LG+G FG V  A     N  VA+K      L+  ++  +    E +I++ L H  +V       S +   I+T+    G + D  L   +  EV    +I+      + MH       VHRDL+  NVL V+   N    +ADFG+ + +  E++     AG+   + + APE +         D+WS G+ +T  +  G  P+   S +  +     S     F MP   N   ++   +L+       +RPT  E L D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>2.49309e-07</Hsp_evalue>
      <Hsp_query-from>485</Hsp_query-from>
      <Hsp_query-to>1153</Hsp_query-to>
      <Hsp_hit-from>157</Hsp_hit-from>
      <Hsp_hit-to>401</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>257</Hsp_align-len>
      <Hsp_qseq>EHNTWEIDRRDLKDIEKLGSGQFGEVWLA-----------LYKQNMKVAVKKLREGSMSCEAFLGEANIMKTLRHERLVQLYAVVS--SEPILIITEYMEKGSMLDFLRSEEGREVLI-PRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCK---VADFGLTRIVEDNEYTSKAGTKFPVRWTAPEA-----------------MHFGHFTTKSDVWSFGILLTEMITYGKIPYAGMSHQQLISNLDKG</Hsp_qseq>
      <Hsp_hseq>EVDQWEITNR------IVGNGTFGHVLITHNSKERDEDVCYHPENYAVKIIKLKPNK-----FDKEARILLRLDHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKERMHTVVGTP-EYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGISPFYGDGSERSIIQNAKIG</Hsp_hseq>
      <Hsp_midline>E + WEI  R       +G+G FG V +             + +N  V + KL+        F  EA I+  L H  ++++Y      +  + I  + +  G +  +L   +    +     +L+  ++   +++L     VHRDL+  N+L+ +   C    +ADFG+ + +  N+         P  + APE                  +    + +K D+WS G++   M+T     Y   S + +I N   G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>3.37385e-07</Hsp_evalue>
      <Hsp_query-from>719</Hsp_query-from>
      <Hsp_query-to>1087</Hsp_query-to>
      <Hsp_hit-from>232</Hsp_hit-from>
      <Hsp_hit-to>359</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>128</Hsp_align-len>
      <Hsp_qseq>ILIITEYMEKGSM-LDFLRSEEGREVLIPRLIL-MAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEYTSKAGTKFPVR--WTAPEAMHFG-HFTTKSDVWSFGILLTEMI</Hsp_qseq>
      <Hsp_hseq>VHMVYEYAEHDLLQIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDGCVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELI</Hsp_hseq>
      <Hsp_midline>+ ++ EY E   + +    S   + ++ PR++  +  ++ DG+ +L +   +HRDL+ AN++V      K+ D GL R   +   T   G K  V   + APE +    H+T   D+WS G +  E+I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>4.16424e-07</Hsp_evalue>
      <Hsp_query-from>491</Hsp_query-from>
      <Hsp_query-to>943</Hsp_query-to>
      <Hsp_hit-from>131</Hsp_hit-from>
      <Hsp_hit-to>299</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>54</Hsp_gaps>
      <Hsp_align-len>187</Hsp_align-len>
      <Hsp_qseq>NTWEIDRRDLKDIEKLGSGQFGEVWLA---LYKQNMKVAV-----KKLRE------GSMSCE--AFLGEANIMKTLRHERLVQLYAVVS---SEPILIITEYMEKG-----------------SMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLT</Hsp_qseq>
      <Hsp_hseq>NTYEI-------IKELGHGQHGKVKLARDILSKQLVAIKIVDRHEKKQRKFFTFIKSSKISENDKIKREIAIMKKCHHKHVVQLIEVLDDLKSRKIYLVLEYCSRGEVKWCPPDCMESDAKGPSLLSF---QETREIL--RGVVL------GLEYLHYQGIIHRDIKPANLLISGDGTVKISDFGVS</Hsp_hseq>
      <Hsp_midline>NT+EI       I++LG GQ G+V LA   L KQ + + +     KK R+       S   E      E  IMK   H+ +VQL  V+    S  I ++ EY  +G                 S+L F   +E RE+L  R +++      G+ +L     +HRD++ AN+L++     K++DFG++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.9878</Hsp_bit-score>
      <Hsp_score>123</Hsp_score>
      <Hsp_evalue>6.61432e-07</Hsp_evalue>
      <Hsp_query-from>692</Hsp_query-from>
      <Hsp_query-to>1087</Hsp_query-to>
      <Hsp_hit-from>775</Hsp_hit-from>
      <Hsp_hit-to>919</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>149</Hsp_align-len>
      <Hsp_qseq>LYAVVSSEPILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIV----------------EDNEYTSKAGTKFPVRWTAPEAMH-FGHFTTKSDVWSFGILLTEMI</Hsp_qseq>
      <Hsp_hseq>MTAVKKKSTLFIQMEYCENRTLYDLIHSENLNQQRDEYWRLFR-QILEALSYIHSQGIIHRDLKPMNIFIDESRNVKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAM---YVATEVLDGTGHYNEKIDMYSLGIIFFEMI</Hsp_hseq>
      <Hsp_midline>+ AV     + I  EY E  ++ D + SE   +       L   ++ + + ++     +HRDL+  N+ ++   N K+ DFGL + V                  +  TS  GT     + A E +   GH+  K D++S GI+  EMI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.447</Hsp_bit-score>
      <Hsp_score>119</Hsp_score>
      <Hsp_evalue>8.48868e-07</Hsp_evalue>
      <Hsp_query-from>518</Hsp_query-from>
      <Hsp_query-to>1087</Hsp_query-to>
      <Hsp_hit-from>41</Hsp_hit-from>
      <Hsp_hit-to>243</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>215</Hsp_align-len>
      <Hsp_qseq>LKDIEKLGSGQFGEV-----------WLALYKQNMKVAVKKLREGSMSCEAFLGEANIMKTLRHERLVQLYAVVSSEPILIITEYM-EKGSMLDFLRS----------EEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLV-NSLLNCKVADFGLTRIVEDNEYTSKAGTKFPVR-WTAPEAM-HFGHFTTKSDVWSFGILLTEMI</Hsp_qseq>
      <Hsp_hseq>VREGKRIGHGSFGTVTQSILSSNSIEWLGPYA--IKRVVKSPKVQSLELE-------ILQNIRHPNLVTLEFFFESHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGIAKVCDFGSAQRLDDN---TELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMI</Hsp_hseq>
      <Hsp_midline>+++ +++G G FG V           WL  Y   +K  VK  +  S+  E       I++ +RH  LV L     S        ++ +K  +++++            + G ++    + L   ++   +  L  M   H DL+ +N+L+  S    KV DFG  + ++DN   ++  T F  R + APE + +   +TT+ D+WS G ++ EMI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>5.54082e-06</Hsp_evalue>
      <Hsp_query-from>515</Hsp_query-from>
      <Hsp_query-to>943</Hsp_query-to>
      <Hsp_hit-from>351</Hsp_hit-from>
      <Hsp_hit-to>497</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>149</Hsp_align-len>
      <Hsp_qseq>DLKDIEKLGSGQFGEVWLALYKQNMKV-AVKKLREGSMSCEAFLG----EANIMKTLRHERLVQLY-AVVSSEPILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLT</Hsp_qseq>
      <Hsp_hseq>DFHTVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYM--AECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLS</Hsp_hseq>
      <Hsp_midline>D   ++ +G G FGEV L   K   K+ A+K L +  M  +  L     E +++       +V LY +   ++ + +I E++  G ++  L   +     + R  +  AE    +  + K+ ++HRD++  N+L++   + K++DFGL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>5.67261e-06</Hsp_evalue>
      <Hsp_query-from>533</Hsp_query-from>
      <Hsp_query-to>1105</Hsp_query-to>
      <Hsp_hit-from>28</Hsp_hit-from>
      <Hsp_hit-to>231</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>209</Hsp_align-len>
      <Hsp_qseq>KLGSGQFGEVWLALYKQN---MKVAVKKLREG---SMSCEAFLGEANIMKTLR-HERLVQL-------YAVVSSEPILIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVEDNEYTSKA---GTKFPVRWTAPEA-MHFGHFTTKSDVWSFGILLTEMITYGKIP</Hsp_qseq>
      <Hsp_hseq>KIGRGSHSLICSSTYTESNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLYEELME-CDLSQIIRSEQRLED--AHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELL--GRKP</Hsp_hseq>
      <Hsp_midline>K+G G    +  + Y ++     VA++K+       +SC+  L E  +++ LR H  +V L       Y   +   + +  E ME   +   +RSE+  E           ++   + ++     +H DL+  N+LVNS    K+ +FGL+    +N   +     G    + + APE  +++   T   D+WS G +L E++  G+ P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YIL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:183937:186369:1 gene:YIL095W transcript:YIL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRK1 description:Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton and reduces endocytic ability of cell through the phosphorylation of the Pan1p-Sla1p-End3p protein complex; PRK1 has a paralog, ARK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001357]</Hit_def>
  <Hit_accession>YIL095W</Hit_accession>
  <Hit_len>810</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>5.75838e-06</Hsp_evalue>
      <Hsp_query-from>521</Hsp_query-from>
      <Hsp_query-to>1123</Hsp_query-to>
      <Hsp_hit-from>23</Hsp_hit-from>
      <Hsp_hit-to>255</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>235</Hsp_align-len>
      <Hsp_qseq>KDIEKLGSGQFGEVWLALYK-----QNMKVAVKK--LREGSMSCEAFLGEANIMKTLRHERLVQLY----AVVSSEPI----LIITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADG---MHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIV--------EDNEYTSKAGTKFPVRWTAPEAMHFGH---FTTKSDVWSFGILLTEMITYGKIPY-----AGMSH</Hsp_qseq>
      <Hsp_hseq>KIIKYLTSGGFAQVYTAEISPPDPYSNANIACLKRVIVPHKQGLNTLRAEVDAMKLLRNNKHVVSYIDSHAARSVNGIAYEVFVLMEFCERGGLIDFMNTRLQNRLQESEILEIMSQTVQGITAMHALQPP-LIHRDIKIENVLISHDGLYKVCDFGSVSGVIRPPRNTQEFNYVQHDILTNTTAQYRSPEMIDLYRGLPIDEKSDIWALGVFLYK-ICYYTTPFEKSGEAGILH</Hsp_hseq>
      <Hsp_midline>K I+ L SG F +V+ A         N  +A  K  +            E + MK LR+ + V  Y    A  S   I     ++ E+ E+G ++DF+ +     +    ++ + ++   G   MH L+    +HRD++  NVL++     KV DFG    V        E N       T    ++ +PE +          KSD+W+ G+ L + I Y   P+     AG+ H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>6.07923e-06</Hsp_evalue>
      <Hsp_query-from>530</Hsp_query-from>
      <Hsp_query-to>1114</Hsp_query-to>
      <Hsp_hit-from>15</Hsp_hit-from>
      <Hsp_hit-to>232</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>EKLGSGQFGEVWLALYKQN------MKVAVKKLREGSMSCEAFLGEANIMKTL---RHERLVQLYAVVSSEPIL-IITEYMEKGSMLDFLRSEEGREVLIPRLILMAAEVADGMHHLEKMRYVHRDLRAANVLVNSLLNCKVADFGLTRIVE------------------DNEY-TSKAGTKFPVRWTAPEAMHFGHFTTKSDVWSFGILLTEMITYGKIPYAG</Hsp_qseq>
      <Hsp_hseq>EELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRH--FTAQLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGT---AEYVSPELLLYNQCGYGSDIWALGCMIYQFVQ-GQPPFRG</Hsp_hseq>
      <Hsp_midline>E+LG G +  V+ AL K++      +KV  KK        +    E N M  L    H  +++LY     E  L  + ++   G +L  L        +  R     A++ D +  +     +HRDL+  NVL++      + DFG    ++                  DN+   S  GT     + +PE + +      SD+W+ G ++ + +  G+ P+ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2339721546</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0032384-RA transcript Note:&quot;Similar to SLCO5A1 Solute carrier organic anion transporter family member 5A1 (Homo sapiens)&quot; offset:0 AED:0.26 eAED:0.31 QI:0|0|0|1|0|0|2|0|262</Iteration_query-def>
  <Iteration_query-len>789</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>88</Statistics_hsp-len>
      <Statistics_eff-space>408321725</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058475-RA transcript Note:&quot;Similar to SLCO5A1 Solute carrier organic anion transporter family member 5A1 (Homo sapiens)&quot; offset:0 AED:0.15 eAED:0.15 QI:0|0.42|0.37|1|1|0.87|8|3466|575</Iteration_query-def>
  <Iteration_query-len>5194</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>103</Statistics_hsp-len>
      <Statistics_eff-space>3637386676</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0043683-RA transcript Note:&quot;Similar to Pomc Pro-opiomelanocortin (Rattus norvegicus)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0|0|3|0|129</Iteration_query-def>
  <Iteration_query-len>390</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>79</Statistics_hsp-len>
      <Statistics_eff-space>122026017</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0043684-RA transcript Note:&quot;Similar to zgc:162928 Uncharacterized protein C8orf34 homolog (Danio rerio)&quot; offset:0 AED:0.52 eAED:1.00 QI:0|0|0|0.14|0|0.07|14|890|411</Iteration_query-def>
  <Iteration_query-len>2126</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1389332737</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058462-RA transcript Note:&quot;Similar to Pkhd1l1 Fibrocystin-L (Mus musculus)&quot; offset:0 AED:0.35 eAED:0.35 QI:0|0.04|0.04|0.50|1|1|63|0|3368</Iteration_query-def>
  <Iteration_query-len>10107</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>108</Statistics_hsp-len>
      <Statistics_eff-space>7178331687</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058472-RA transcript Note:&quot;Similar to SLC39A12 Zinc transporter ZIP12 (Bos taurus)&quot; offset:0 AED:0.27 eAED:0.27 QI:0|0|0|0.5|1|1|4|0|138</Iteration_query-def>
  <Iteration_query-len>417</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>80</Statistics_hsp-len>
      <Statistics_eff-space>140777953</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0043681-RA transcript Note:&quot;Similar to TMEM68 Transmembrane protein 68 (Bos taurus)&quot; offset:0 AED:0.28 eAED:0.28 QI:0|0|0|0.75|1|1|4|0|183</Iteration_query-def>
  <Iteration_query-len>552</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>84</Statistics_hsp-len>
      <Statistics_eff-space>235966700</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058476-RA transcript Note:&quot;Similar to FBXO32 F-box only protein 32 (Bos taurus)&quot; offset:710 AED:0.04 eAED:0.04 QI:710|0.37|0.66|0.88|0.12|0.22|9|2536|282</Iteration_query-def>
  <Iteration_query-len>4095</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>102</Statistics_hsp-len>
      <Statistics_eff-space>2830215021</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058485-RA transcript Note:&quot;Similar to PIWIL1 Piwi-like protein 1 (Gallus gallus)&quot; offset:145 AED:0.19 eAED:0.19 QI:145|0.88|0.94|1|0.11|0.16|18|1456|737</Iteration_query-def>
  <Iteration_query-len>3815</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2629536390</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0048371-RA transcript Note:&quot;Similar to SYCP2 Synaptonemal complex protein 2 (Homo sapiens)&quot; offset:29 AED:0.42 eAED:0.42 QI:29|0.90|0.83|0.91|0|0|12|298|484</Iteration_query-def>
  <Iteration_query-len>1782</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1141246433</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0043691-RA transcript Note:&quot;Similar to ARFGEF1 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Homo sapiens)&quot; offset:762 AED:0.11 eAED:0.14 QI:762|0.33|0.27|0.92|0.56|0.52|40|4576|1296</Iteration_query-def>
  <Iteration_query-len>9229</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDR170C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:796193:802222:-1 gene:YDR170C transcript:YDR170C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SEC7 description:Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors; involved in proliferation of the Golgi, intra-Golgi transport and ER-to-Golgi transport; found in the cytoplasm and on Golgi-associated coated vesicles [Source:SGD;Acc:S000002577]</Hit_def>
  <Hit_accession>YDR170C</Hit_accession>
  <Hit_len>2009</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>596.275</Hsp_bit-score>
      <Hsp_score>1536</Hsp_score>
      <Hsp_evalue>8.88289e-176</Hsp_evalue>
      <Hsp_query-from>1195</Hsp_query-from>
      <Hsp_query-to>4794</Hsp_query-to>
      <Hsp_hit-from>411</Hsp_hit-from>
      <Hsp_hit-to>1660</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>405</Hsp_identity>
      <Hsp_positive>670</Hsp_positive>
      <Hsp_gaps>126</Hsp_gaps>
      <Hsp_align-len>1288</Hsp_align-len>
      <Hsp_qseq>AQEIVQKILNEVVSTVAAESEDGSAGSHTGTLEEEGSGPNDAEPTHANGVPGGTIPPYTPSLPDDRISVSSTDTQESGVAPGQPPVVKFSH--ILQKDAFLVFRSLCKLSMKPLSDGPPDPKSHELRSKIXXXXXXXXXXXNAGPVFRTNEMF---------INAIKQYLCVALSKNGVSSIPEVFELSLAIFLTLLSNFKTHLKMQIEVFFKEIFLNILETSSSSFEHKWMVIQTLTRICADAQCVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRS----------------------------------------GQELGITPNQELSLRKKGLDCLVSILKCMVEWSKDQYINPNSQSNLGIL--ALALVRADTGQERPAEQDATVDSRHPETIGRYGSVNSLDSTASSGIGSVSTQLSGADNPEQFEVLKQQKEIIEQGIELFNKKPKRGIQFLQEQNMLGTTTE-DVAQFLHSENRLDSTQVGDYLGENDKLNKETMYTYVDQMDFSGKDFVSALRLFLEGFRLPGEAQKIDRLMEKFAARFCECNQGQTVFASADTAYVLAYSIIMLTTDLHSLQVKHKMSKEQYIKMNRGINDSKDLPEEYLSSIYDEIAGKKIAMNESKEFAQISRPPKPNVASERQRRLLY----NLEMEAMSRTAKALMEAVSHV----------QAAFTSATHLDHVRPMFKLAWTPFLAAFSVGLQDCDDTEVASLCLDGIRGAIRIACIFHMQLERDAYVQALARFTLLTANSGITEMKQKNIDTIKTLIMVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKSRYITGTSRRREGTASGAGITT-DDFTGLGPLGGGNVDRKQIA-------SIQESIGE-TSSQSVVVAVDRIFTGSTRLDGNAIVDFVRCLCAVSMDELAS---PSHPRMFSLQKIVEISYYNMGRIRLQWSRIWEVVGDHFNKVGCNPNEDVAFFALDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKRNRSPTVRDMVVRCITQMVNSQAANIRSGWKNIFSVFHLAASDQDESIV-ELAFQTTSHIVTTVFERHFPTTIDSFQDAVKCLSEFACNAAFPDTSMEAIRLIRHCAKYVSE-----RPQTFREHTSDDINVVPEDRVWVRGWFPILFELS-CIINRCKLDVRTRGLTVMFEIMKTYGHTFEKHWWQDLF-RIVFRIFDNMKLPEQQTEVKSVRGNIFFTDFLRCWVG*TINRAGGVSRGY*TIAFCRLQRLVNSGMLHLVLFTLFKDHCVWGRWG</Hsp_qseq>
      <Hsp_hseq>AQATLTQIISSVYDKIDLKQSTSSAVSLSTKNHQQQSAIELSEASENAETPAPLTLENMDKLNDD---------EERLMDAQQPDSIAITNQDLAVKDAFLVFRVMAKICAKPL-ETELDMRSHAVRSKLLSLHIIYSIIKDHIDVFLSHNIFLPGKERVCFIDSIRQYLRLVLSRNAASPLAPVFEVTLEIMWLLIANLRADFVKEIPVFLTEIYFPISELTTSTSQQKRYFLSVIQRICNDPRTLVEFYLNYDCNPGMPNVMEITVDYLTRLALTRVEITQTQRSYYDEQISKSLSTYNFSQLPLLTSSNLSSSPDVGQVNLLFP-LDFALKMVSLNCIVSVLRSLSSWAH-KALNPNTHTANKVLLNTTSSARQESRSSLSNDVRSSIMTSNDDFKPTYEDEES---------RSLSSQNIDADDPTQFENLKLRKTALSECIAIFNNKPKKAIPVLIKKGFLKDDSPISIAKWLLETEGLDMAAVGDYLGEGDDKNIAIMHAFVDEFDFTGMSIVDALRSFLQSFRLPGEGQKIDRFMLKFAERFVDQNPG--VFSKADTAYVLSYSLIMLNTDLHSSQIKNKMSLQEFLENNEGIDNGRDLPRDFLEGLFNEIANNEIKLISEQHQAMLS--GDTNLVQQQQSAFNFFNSRDLTREAYNQVSKEISSKTELVFKNLNKNKGGPDVYYAASHVEHVKSIFETLWMSFLAALTPPFKDYDDIDTTNKCLEGLKISIKIASTFRINDARTSFVGALVQFCNL---QNLEEIKVKNVNAMVILLEVALSEGNYLEGSWKDILLVVSQMERLQLISKGIDRDTVPDVAQARVANPRVSYESSRSNNTSFFDVWGKKATPTELAQEKHHNQTLSPEISKFISSSELVVLMDNIFTKSSELSGNAIVDFIKALTAVSLEEIESSENASTPRMFSLQKMVDVCYYNMDRIKLEWTPLWAVMGKAFNKIATNSNLAVVFFAIDSLRQLSMRFLDIEELSGFEFQHDFLKPFEYTVQNSGNTEVQEMIIECFRNFILTKSESIKSGWKPILESLQYTARSSTESIVLKTQLLVSNDIVTNHFENVFSQE-DAFSELVGVFREITKNKRFQKLSLHALESLRKMTQNVADICFYNENKTEEERKHNDALLRGKD-IFQDVWFPMLFCFNDTIMTAEDLEVRSRALNYMFDALVAYGGKFNDDFWEKICKKLLFPIFGVLS---KHWEVNQFNSH----DDLSVWLSTTLIQALRNLIALFTHYFESLNRMLD-GFLGLLVSCICQENDTIARIG</Hsp_hseq>
      <Hsp_midline>AQ  + +I++ V   +  +    SA S +    ++ S    +E +     P          L DD         +E  +   QP  +  ++  +  KDAFLVFR + K+  KPL +   D +SH +RSK+LSL ++ S++++   VF ++ +F         I++I+QYL + LS+N  S +  VFE++L I   L++N +     +I VF  EI+  I E ++S+ + K   +  + RIC D + +V+ Y+NYDC+    N+ E  V+ L+++A  R                                         GQ   + P  + +L+   L+C+VS+L+ +  W+  + +NPN+ +   +L    +  R ++      +  +++ + + +    Y    S          S+S+Q   AD+P QFE LK +K  + + I +FN KPK+ I  L ++  L   +   +A++L     LD   VGDYLGE D  N   M+ +VD+ DF+G   V ALR FL+ FRLPGE QKIDR M KFA RF + N G  VF+ ADTAYVL+YS+IML TDLHS Q+K+KMS +++++ N GI++ +DLP ++L  +++EIA  +I +   +  A +S     N+  ++Q    +    +L  EA ++ +K +      V             + +A+H++HV+ +F+  W  FLAA +   +D DD +  + CL+G++ +I+IA  F +   R ++V AL +F  L     + E+K KN++ +  L+ VA ++GNYL  SW +IL  +SQ+E  QLI  G+    +   ++ R      +  ++  + T    + G      ++A       ++   I +  SS  +VV +D IFT S+ L GNAIVDF++ L AVS++E+ S    S PRMFSLQK+V++ YYNM RI+L+W+ +W V+G  FNK+  N N  V FFA+DSLRQLSM+FL+  EL+ F FQ DFL+PFE+ ++ + +  V++M++ C    + +++ +I+SGWK I       A    ESIV +     ++ IVT  FE  F    D+F + V    E   N  F   S+ A+  +R   + V++       +T  E   +D  +  +D ++   WFP+LF  +  I+    L+VR+R L  MF+ +  YG  F   +W+ +  +++F IF  +    +  EV     +    D L  W+  T+ +A        T  F  L R+++ G L L++  + +++    R G</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>121.709</Hsp_bit-score>
      <Hsp_score>304</Hsp_score>
      <Hsp_evalue>1.39323e-27</Hsp_evalue>
      <Hsp_query-from>6157</Hsp_query-from>
      <Hsp_query-to>7401</Hsp_query-to>
      <Hsp_hit-from>1584</Hsp_hit-from>
      <Hsp_hit-to>2005</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>108</Hsp_identity>
      <Hsp_positive>205</Hsp_positive>
      <Hsp_gaps>73</Hsp_gaps>
      <Hsp_align-len>455</Hsp_align-len>
      <Hsp_qseq>RFVCPSSGVVATDVFISTRPPPDQKTEWMTTTCNHALYAICDVFTQYYEVLDDILLDDIFSQLYWCVQQDNEQLARSGTNCLENVVILNGEKFSPSTWDKTCSCMLDIFKTTIPNALLTWRPVGVEGESSPSHGDGSEKPS-----DAVSQRSFDVSV-------RTDEHADRPSGDTW-------KQSQFSLVSTASDEQG----------RGKGLRMSEQK--------LFAALLIKCVVQLELIQTIDNIVFFPATSKKEDAENLAAAQRDSDADVHIDTEDQGMYRYLSSNQLFKLLDCLLESHRFAKAFNASHEQRTALWKAGFKGKSKPNLLKQETSSLACSLRILFRMYMDESRQNAWGEVQNRLIGACSEAFSYFLSL---TSESHREAWTNXXXXXXXXXXXXSDERFRAHASSYYPLLCEIMMFDLVPELRTVLRKFFLRIGAVF</Hsp_qseq>
      <Hsp_hseq>KLLFPIFGVLSKHWEVNQFNSHDDLSVWLSTTLIQALRNLIALFTHYFESLNR-MLDGFLGLLVSCICQENDTIARIGRSCLQQLILQNVSKFNEYHWNQIGDVFDKLFDLTTANELFDYDPLQQGRKSSVSHHQTTNDTSQHSDDDSNDRRENDSNISETVERAHQEESSEDVGGDMVETLNGQTKLNNGNSVPTVKDELNPKPASLSIPKKTKHMKRNESNEDIRRRINIKNSIVVKCVLQLLMIELLNELF-----------------------------ENEDFAHCIPYKEAIRITRLLEKSYEFSRDFNEDYGLRTRLVEARVVDKI-PNLLKQETSAAAVLLDIMFQLYLNDDEKKA--DLITRLITICIQVVEGYVSLDDRTMERSINAWRSVIVEILQGYYEFDDEDFRLYCPAMYALVIQILDKSVPTELRHAIKQFLSRVGELY</Hsp_hseq>
      <Hsp_midline>+ + P  GV++    ++     D  + W++TT   AL  +  +FT Y+E L+  +LD     L  C+ Q+N+ +AR G +CL+ +++ N  KF+   W++       +F  T  N L  + P+    +SS SH   +   S     D+  +R  D ++         +E ++   GD         K +  + V T  DE            + K ++ +E          +  ++++KCV+QL +I+ ++ +                              E++     +   +  ++   L +S+ F++ FN  +  RT L +A    K  PNLLKQETS+ A  L I+F++Y+++  + A  ++  RLI  C +    ++SL   T E    AW ++++  L    +  DE FR +  + Y L+ +I+   +  ELR  +++F  R+G ++</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>3</Hsp_num>
      <Hsp_bit-score>102.064</Hsp_bit-score>
      <Hsp_score>253</Hsp_score>
      <Hsp_evalue>1.38636e-21</Hsp_evalue>
      <Hsp_query-from>244</Hsp_query-from>
      <Hsp_query-to>888</Hsp_query-to>
      <Hsp_hit-from>231</Hsp_hit-from>
      <Hsp_hit-to>447</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>120</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>238</Hsp_align-len>
      <Hsp_qseq>LDKILADKDVKKAHHSQLRKACEVALDEIKA-EAEVQSPPAVVDGKVGSSALPPIRSKSNFIEADKYFLPFELACQSKCSRIVSTSLDCLQKLIAYGHLTG----NAPDSTT---------------PGKRLIDRIIETICGCFQGPQTDEGVQLQIIKALLTAVTSQNIE--IHEGTLLQTVRTCYNIYLASKNMINQTTAKATLTQMLNVIFARME-NQALQEAKQMDRDKHPRHA</Hsp_qseq>
      <Hsp_hseq>LETILNDKDIKKNSNAQ--KAIERTLQKFKEFDPQTTNNPHYVDSILVFEAL-------------------RASCRTKSSKVQSLALDCLSKLFSFRSLDETLLVNPPDSLASNDQRQDAADGITPPPKQKIIDAAIDTISDCFQGEGTDDRVELQIVRALSSCILEEDSSSLCHGASLLKAIRTIYNVFVFSLNPSNQGIAQATLTQIISSVYDKIDLKQSTSSAVSLSTKNHQQQS</Hsp_hseq>
      <Hsp_midline>L+ IL DKD+KK  ++Q  KA E  L + K  + +  + P  VD  +   AL                     +C++K S++ S +LDCL KL ++  L      N PDS                 P +++ID  I+TI  CFQG  TD+ V+LQI++AL + +  ++     H  +LL+ +RT YN+++ S N  NQ  A+ATLTQ+++ ++ +++  Q+   A  +    H + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YEL022W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:111421:115800:1 gene:YEL022W transcript:YEL022W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GEA2 description:Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs); involved in vesicular transport between the Golgi and ER, Golgi organization, and actin cytoskeleton organization; GEA2 has a paralog, GEA1, that arose from the whole genome duplication [Source:SGD;Acc:S000000748]</Hit_def>
  <Hit_accession>YEL022W</Hit_accession>
  <Hit_len>1459</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>130.568</Hsp_bit-score>
      <Hsp_score>327</Hsp_score>
      <Hsp_evalue>2.51681e-30</Hsp_evalue>
      <Hsp_query-from>2326</Hsp_query-from>
      <Hsp_query-to>2913</Hsp_query-to>
      <Hsp_hit-from>550</Hsp_hit-from>
      <Hsp_hit-to>760</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>81</Hsp_identity>
      <Hsp_positive>122</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>214</Hsp_align-len>
      <Hsp_qseq>QFEVLKQQKEIIE--QGIELFNKKPKRGIQFLQEQNMLGTTTE-DVAQFL-HSENRLDSTQVGDYLGENDKLNKETMYTYVDQMDFSGKDFVSALRLFLEGFRLPGEAQKIDRLMEKFAARFCECNQG--------------QTVFASADTAYVLAYSIIMLTTDLHSLQVKHKMSKEQYIKMNRGINDSKDLPEEYLSSIYDEIAGKKIAMNE</Hsp_qseq>
      <Hsp_hseq>EMEILKKRDRKTEFIECTNAFNEKPKKGIPMLIEKGFIASDSDKDIAEFLFNNNNRMNKKTIGLLLCHPDKVS--LLNEYIRLFDFSGLRVDEAIRILLTKFRLPGESQQIERIIEAFSSAYCE-NQDYDPSKISDNAEDDISTVQPDADSVFILSYSIIMLNTDLHNPQVKEHMSFEDYSGNLKGCCNHKDFPFWYLDRIYCSIRDKEIVMPE</Hsp_hseq>
      <Hsp_midline>+ E+LK++    E  +    FN+KPK+GI  L E+  + + ++ D+A+FL ++ NR++   +G  L   DK++   +  Y+   DFSG     A+R+ L  FRLPGE+Q+I+R++E F++ +CE NQ                TV   AD+ ++L+YSIIML TDLH+ QVK  MS E Y    +G  + KD P  YL  IY  I  K+I M E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YJR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:486586:490812:-1 gene:YJR031C transcript:YJR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GEA1 description:Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs); involved in vesicular transport between the Golgi and ER, Golgi organization, and actin cytoskeleton organization; GEA1 has a paralog, GEA2, that arose from the whole genome duplication [Source:SGD;Acc:S000003792]</Hit_def>
  <Hit_accession>YJR031C</Hit_accession>
  <Hit_len>1408</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>115.931</Hsp_bit-score>
      <Hsp_score>289</Hsp_score>
      <Hsp_evalue>7.1203e-26</Hsp_evalue>
      <Hsp_query-from>2317</Hsp_query-from>
      <Hsp_query-to>2913</Hsp_query-to>
      <Hsp_hit-from>529</Hsp_hit-from>
      <Hsp_hit-to>752</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>226</Hsp_align-len>
      <Hsp_qseq>NPEQFEVLKQQKEIIE--QGIELFNKKPKRGIQFLQEQNMLGT-TTEDVAQFLHSEN-RLDSTQVGDYLGENDKLNKETMYTYVDQMDFSGKDFVSALRLFLEGFRLPGEAQKIDRLMEKFAARFC-----------ECNQGQT------------VFASADTAYVLAYSIIMLTTDLHSLQVKHKMSKEQYIKMNRGINDSKDLPEEYLSSIYDEIAGKKIAMNE</Hsp_qseq>
      <Hsp_hseq>NQKEIDILKQRDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKK--TSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPE</Hsp_hseq>
      <Hsp_midline>N ++ ++LKQ+    E    +E FN+K K+GIQ L E+  + + +  D+A FL   N RL+   +G  L +  K     +  ++D  DF G     A+R+ L  FRLPGE+Q+I+R++E F++++            +   G+             V   AD+ +VL+YSIIML TD H+ QVK  M+ + Y    RG  + KD P  YL  IY  I  K+I M E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YPR095C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:721037:724717:-1 gene:YPR095C transcript:YPR095C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SYT1 description:Guanine nucleotide exchange factor (GEF) for Arf proteins; promotes activation of Arl1p, which recruits Imh1p to the Golgi; involved in vesicular transport; member of the Sec7-domain family; contains a PH domain [Source:SGD;Acc:S000006299]</Hit_def>
  <Hit_accession>YPR095C</Hit_accession>
  <Hit_len>1226</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>1.49257e-07</Hsp_evalue>
      <Hsp_query-from>2497</Hsp_query-from>
      <Hsp_query-to>2898</Hsp_query-to>
      <Hsp_hit-from>477</Hsp_hit-from>
      <Hsp_hit-to>621</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>145</Hsp_align-len>
      <Hsp_qseq>VGDYLGENDKLNKETMYTYV--DQMDFSGKDFVSALRLFLEGFRLPGEAQKIDRLMEKFAARFCECNQG-------QTVFASADTAYVLAYSIIMLTTDLHSLQVKHKMSKEQYIKM--NRGINDSKDLPEEYLSSIYDEIAGKK</Hsp_qseq>
      <Hsp_hseq>IGIILTEKDDEFKKNCLNYLLTNCFEFKNDPLDIALRKLLMFLELPKETQQIDRLIMAFSFAYYKAQKSYSKKKGIECPWSNADQVYFIAFSLLMLHTDYFNPNNKSKMTKHDFVDLVHNDKYSGGNEIPMAVLTYFYENVTAKE</Hsp_hseq>
      <Hsp_midline>+G  L E D   K+    Y+  +  +F       ALR  L    LP E Q+IDRL+  F+  + +  +        +  +++AD  Y +A+S++ML TD  +   K KM+K  ++ +  N   +   ++P   L+  Y+ +  K+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>108</Statistics_hsp-len>
      <Statistics_eff-space>6533360456</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058486-RA transcript Note:&quot;Similar to Arfgef1 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Mus musculus)&quot; offset:0 AED:0.36 eAED:0.36 QI:0|0.8|0.5|1|1|1|6|2349|322</Iteration_query-def>
  <Iteration_query-len>3318</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDR170C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:796193:802222:-1 gene:YDR170C transcript:YDR170C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SEC7 description:Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors; involved in proliferation of the Golgi, intra-Golgi transport and ER-to-Golgi transport; found in the cytoplasm and on Golgi-associated coated vesicles [Source:SGD;Acc:S000002577]</Hit_def>
  <Hit_accession>YDR170C</Hit_accession>
  <Hit_len>2009</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>4.28922e-07</Hsp_evalue>
      <Hsp_query-from>301</Hsp_query-from>
      <Hsp_query-to>927</Hsp_query-to>
      <Hsp_hit-from>1817</Hsp_hit-from>
      <Hsp_hit-to>2005</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>220</Hsp_align-len>
      <Hsp_qseq>ALLIKCVVQLELIQTIDNIVFFPATSKKEDAENLAAAQRDSDADVHIDTEDQGMYRYLSSNQLFKLLDCLLESHRFAKAFNASHEQRTALWKAG-----RGLARNHLACS---LRILFRMYMDESRQNAWGEVQNRLIGACSEAFSYFLSL---TSESHREAWTNXXXXXXXXXXXXSDERFRAHASSYYPLLCEIMMFDLVPELRTVLRKFFLRIGAVF</Hsp_qseq>
      <Hsp_hseq>SIVVKCVLQLLMIELLNELF-----------------------------ENEDFAHCIPYKEAIRITRLLEKSYEFSRDFNEDYGLRTRLVEARVVDKIPNLLKQETSAAAVLLDIMFQLYLNDDEKKA--DLITRLITICIQVVEGYVSLDDRTMERSINAWRSVIVEILQGYYEFDDEDFRLYCPAMYALVIQILDKSVPTELRHAIKQFLSRVGELY</Hsp_hseq>
      <Hsp_midline>++++KCV+QL +I+ ++ +                              E++     +   +  ++   L +S+ F++ FN  +  RT L +A        L +   + +   L I+F++Y+++  + A  ++  RLI  C +    ++SL   T E    AW ++++  L    +  DE FR +  + Y L+ +I+   +  ELR  +++F  R+G ++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2267591402</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0058487-RA transcript Note:&quot;Similar to TAF2 Transcription initiation factor TFIID subunit 2 (Gallus gallus)&quot; offset:1064 AED:0.32 eAED:0.32 QI:1064|0.70|0.77|0.94|0.64|0.61|18|0|703</Iteration_query-def>
  <Iteration_query-len>3176</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YCR042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:201174:205397:-1 gene:YCR042C transcript:YCR042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TAF2 description:TFIID subunit (150 kDa); involved in RNA polymerase II transcription initiation [Source:SGD;Acc:S000000638]</Hit_def>
  <Hit_accession>YCR042C</Hit_accession>
  <Hit_len>1407</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>101.679</Hsp_bit-score>
      <Hsp_score>252</Hsp_score>
      <Hsp_evalue>3.2812e-22</Hsp_evalue>
      <Hsp_query-from>1983</Hsp_query-from>
      <Hsp_query-to>2999</Hsp_query-to>
      <Hsp_hit-from>677</Hsp_hit-from>
      <Hsp_hit-to>1074</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>106</Hsp_identity>
      <Hsp_positive>175</Hsp_positive>
      <Hsp_gaps>83</Hsp_gaps>
      <Hsp_align-len>410</Hsp_align-len>
      <Hsp_qseq>SGVVKFYGTFVFNRKRNILELELKQDCIAQ-GTQKY--------------------------GPLTVTVQELDGS-FNHNLQIEENSTRHEIPCHSKSRRNKKK-------------------------------------KIPLLNGEEIDMDLSLMDADSPLLWIRIDPEMSILRRVELEQPDFMWQYELRYERDVVAQGEAISALERFPTPQS--RLALTDILEH----EQCFYRVRMQSTFCLAQIANAMVNTWNGPPAMKSIFTRMFCCKTCPNIIKTNNFCNFQSYFLLKTIPVTMAMQRDIHGMCPKEVLTFLLDLIKYNDNRKNKFSDNYYRASLIEALANSVTPAVAVSNENRTVENLNADVRLVLEEITRFLNMEKLLPCYRHTVTISCLKAIRVLQKNG</Hsp_qseq>
      <Hsp_hseq>SGVPILRVTQRFNRKRMVIELGIRQVQDEELGHEKVVGEEGFFKSALDHLEHPDLNRTECFTGSMTIRIHEHDGTPYEHIVEIKDTFTKIDIQYNTKYRRLRKRGGGANDENGVENNNEEKPIVVDVNCLGNVYMSPEECSRFSLTEFNRTSESNELLKQNEAFEWIRIDSDLEWICQMHINQPDYMFSSQLRQDGDIEAQLEAIRYYEDVVVNGGVKSLVYSSILFRTAIDERYFFGIRLAACEALSKYVYDPDFT-GGVKHLIQIFQILFCLEDS-NIPKSNNFENPKLYFLQCNIPKYLAKVKNENGKCPKLVKQFLLDILVYNENGENKYSDDAYVRSLIE---NVVKVALNEYKDKAYMEKVKT-------QLLRYENLVNWLSSYESLIKTTIMYAKYKLHKVG</Hsp_hseq>
      <Hsp_midline>SGV     T  FNRKR ++EL ++Q    + G +K                           G +T+ + E DG+ + H ++I++  T+ +I  ++K RR +K+                                     +  L           L+  +    WIRID ++  + ++ + QPD+M+  +LR + D+ AQ EAI   E          L  + IL      E+ F+ +R+ +   L++       T  G   +  IF  +FC +   NI K+NNF N + YFL   IP  +A  ++ +G CPK V  FLLD++ YN+N +NK+SD+ Y  SLIE   N V  A+    +   +E +         ++ R+ N+   L  Y   +  + + A   L K G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2159396186</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

