<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0052387-RA transcript Note:&quot;Similar to BAG4 BAG family molecular chaperone regulator 4 (Homo sapiens)&quot; offset:189 AED:0.16 eAED:0.16 QI:189|0.5|0.66|1|1|1|3|1481|239</BlastOutput_query-def>
  <BlastOutput_query-len>2390</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052387-RA transcript Note:&quot;Similar to BAG4 BAG family molecular chaperone regulator 4 (Homo sapiens)&quot; offset:189 AED:0.16 eAED:0.16 QI:189|0.5|0.66|1|1|1|3|1481|239</Iteration_query-def>
  <Iteration_query-len>2390</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1582552366</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052389-RA transcript Note:&quot;Similar to INPP5F Phosphatidylinositide phosphatase SAC2 (Homo sapiens)&quot; offset:150 AED:0.15 eAED:0.15 QI:150|0.68|0.85|1|0.94|0.9|20|1013|922</Iteration_query-def>
  <Iteration_query-len>3932</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YKL212W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:34543:36414:1 gene:YKL212W transcript:YKL212W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAC1 description:Phosphatidylinositol phosphate (PtdInsP) phosphatase; involved in hydrolysis of PtdIns[4]P in the early and medial Golgi; regulated by interaction with Vps74p; ER localized transmembrane protein which cycles through the Golgi; involved in protein trafficking and processing, secretion, and cell wall maintenance; regulates sphingolipid biosynthesis through the modulation of PtdIns(4)P metabolism [Source:SGD;Acc:S000001695]</Hit_def>
  <Hit_accession>YKL212W</Hit_accession>
  <Hit_len>623</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>183.726</Hsp_bit-score>
      <Hsp_score>465</Hsp_score>
      <Hsp_evalue>5.21354e-49</Hsp_evalue>
      <Hsp_query-from>757</Hsp_query-from>
      <Hsp_query-to>1683</Hsp_query-to>
      <Hsp_hit-from>170</Hsp_hit-from>
      <Hsp_hit-to>503</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>124</Hsp_identity>
      <Hsp_positive>174</Hsp_positive>
      <Hsp_gaps>81</Hsp_gaps>
      <Hsp_align-len>362</Hsp_align-len>
      <Hsp_qseq>QEDERADFWIMPVIQGFVQIEKLVVKYGDXXXXXXXXXXXXXXXXXXXXXHPEFLVALISRRSRHRAGMRYKRRGVDRDGHVANFVETEQLIHIHT------HTLSFVQTRGSVPVYWSQAGYTYNPRPQLTKGDKETRDAFEFHFKKQLEIYQRQVVVNLVDQAGREKIIGD------------------------TRGMKFENVHILTDAICEI---ISDMKWCWADAAG----LIQVQQGVFRVNCMDCLDRTNVVQAAIARIVMESQL----------------PIKCRRIYQVMWANHGDTVSRQYAGTAALKGDFTRTGERRFAGVMKDGYNSANRYYLNQFRDAYRQAAIDLMQG</Hsp_qseq>
      <Hsp_hseq>HQDPRIDSFIQPVIYGYAKTVDAVLN------------------------ATPIVLGLITRRSIFRAGTRYFRRGVDKDGNVGNFNETEQILLAENPESEKIHVFSFLQTRGSVPIYWAEIN-NLKYKPNLVLGEN-SLDATKKHFDQQKELYGDNYLVNLVNQKGHELPVKEGYESVVHALNDPKIHYVYFDFHHECRKMQWHRVKLLIDHLEKLGLSNEDFFHKVIDSNGNTVEIVNEQHSVVRTNCMDCLDRTNVVQSVLAQWVLQKEFESADVVATGSTWEDNAPLLTS--YQNLWADNADAVSVAYSGTGALKTDFTRTGKRTRLGAFNDFLNSASRYYQNNWTDGPRQDSYDLFLG</Hsp_hseq>
      <Hsp_midline> +D R D +I PVI G+ +    V+                             ++ LI+RRS  RAG RY RRGVD+DG+V NF ETEQ++          H  SF+QTRGSVP+YW++       +P L  G+  + DA + HF +Q E+Y    +VNLV+Q G E  + +                         R M++  V +L D + ++     D      D+ G    ++  Q  V R NCMDCLDRTNVVQ+ +A+ V++ +                 P+     YQ +WA++ D VS  Y+GT ALK DFTRTG+R   G   D  NSA+RYY N + D  RQ + DL  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YNL106C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:420944:424495:-1 gene:YNL106C transcript:YNL106C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:INP52 description:Polyphosphatidylinositol phosphatase; dephosphorylates a number of phosphatidylinositol phosphates (PtdInsPs, PIPs) to PI; involved in endocytosis; hyperosmotic stress causes translocation to actin patches; synaptojanin-like protein with a Sac1 domain; INP52 has a paralog, INP53, that arose from the whole genome duplication [Source:SGD;Acc:S000005050]</Hit_def>
  <Hit_accession>YNL106C</Hit_accession>
  <Hit_len>1183</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>167.162</Hsp_bit-score>
      <Hsp_score>422</Hsp_score>
      <Hsp_evalue>3.05334e-42</Hsp_evalue>
      <Hsp_query-from>922</Hsp_query-from>
      <Hsp_query-to>1683</Hsp_query-to>
      <Hsp_hit-from>260</Hsp_hit-from>
      <Hsp_hit-to>556</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>98</Hsp_identity>
      <Hsp_positive>150</Hsp_positive>
      <Hsp_gaps>43</Hsp_gaps>
      <Hsp_align-len>297</Hsp_align-len>
      <Hsp_qseq>VALISRRSRHRAGMRYKRRGVDRDGHVANFVETEQLIHIHTHTLSFVQTRGSVPVYWSQAGYTYNPRPQLTKGDKETRDAFEFHFKKQLEIYQRQVVVNLVDQAGRE--------KIIGDTRGMKFENVHILTD-------------AICEIISDMKWCWADAA---------GLIQVQQGVFRVNCMDCLDRTNVVQAAIA-----------RIVMESQLPIKCRRIYQV--MWANHGDTVSRQYAGTAALKGDFTRTGERRFAGVMKDGYNSANRYYLNQFRDAYRQAAIDLMQG</Hsp_qseq>
      <Hsp_hseq>LTIISRQSWKRAGTRFNARGIDDDGHVANFVETEMIMYSSQYCYAFTQIRGSLPIFWEQDTSLISPKIQITRSVEATQPTFDEHFIRLFKKYGPVHIINLLSTKSSEIQLSRRYKEQLKNSEKMKIGRDVFLTSFDFHRETSQDGFAAASRIIPKIRNTILDAGYFSYDVKEGRLISEQDGVFRTNCLDCLDRTNLIQQTISLAVFKLFLEDFRLVKPSSFIDDNEFVQKVNALWADNGDQISQIYTGTNALKSSYSRKGKMSFSGALSDATKSVSRMYINNFVDKGKQQNIDTLLG</Hsp_hseq>
      <Hsp_midline>+ +ISR+S  RAG R+  RG+D DGHVANFVETE +++   +  +F Q RGS+P++W Q     +P+ Q+T+  + T+  F+ HF +  + Y    ++NL+     E        + + ++  MK      LT              A   II  ++    DA           LI  Q GVFR NC+DCLDRTN++Q  I+           R+V  S        + +V  +WA++GD +S+ Y GT ALK  ++R G+  F+G + D   S +R Y+N F D  +Q  ID + G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YOR109W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:525278:528601:1 gene:YOR109W transcript:YOR109W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:INP53 description:Polyphosphatidylinositol phosphatase; dephosphorylates multiple phosphatidylinositol phosphates; involved in trans Golgi network-to-early endosome pathway; hyperosmotic stress causes translocation to actin patches; contains Sac1 and 5-ptase domains; INP53 has a paralog, INP52, that arose from the whole genome duplication [Source:SGD;Acc:S000005635]</Hit_def>
  <Hit_accession>YOR109W</Hit_accession>
  <Hit_len>1107</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>161.77</Hsp_bit-score>
      <Hsp_score>408</Hsp_score>
      <Hsp_evalue>1.22627e-40</Hsp_evalue>
      <Hsp_query-from>922</Hsp_query-from>
      <Hsp_query-to>1689</Hsp_query-to>
      <Hsp_hit-from>235</Hsp_hit-from>
      <Hsp_hit-to>534</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>99</Hsp_identity>
      <Hsp_positive>142</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>300</Hsp_align-len>
      <Hsp_qseq>VALISRRSRHRAGMRYKRRGVDRDGHVANFVETEQLIHIHTHTLSFVQTRGSVPVYWSQAGYTYNPRPQLTKGDKETRDAFEFHFKKQLEIYQRQVVVNLVDQAGREKIIG----------------------------DTRGMKFENVHILTDAICEIISDMKWCWADA--AGLIQVQQGVFRVNCMDCLDRTNVVQAAIA----RIVMESQLPIKCRRI---------YQVMWANHGDTVSRQYAGTAALKGDFTRTGERRFAGVMKDGYNSANRYYLNQFRDAYRQAAIDLMQG-LP</Hsp_qseq>
      <Hsp_hseq>LTIISKQSWKRAGTRFNARGVDDEANVANFVETEFIMYSSQYCYAFTQIRGSIPVFWEQGTSLINPRVQITRSFEATQPVFDKHIMKSVEKYGPVHVVNLLSTKSSEIELSKRYKEHLTHSKKLNFNKDIFLTEFDFHKETSQEGFSGVRKLIPLILDSLLSSGYYSYDVREKKNISEQHGIFRTNCLDCLDRTNLAQQIISLAAFRTFLEDFRLISSNSFIDDDDFVSKHNTLWADHGDQISQIYTGTNALKSSFSRKGKMSLAGALSDATKSVSRIYINNFMDKEKQQNIDTLLGRLP</Hsp_hseq>
      <Hsp_midline>+ +IS++S  RAG R+  RGVD + +VANFVETE +++   +  +F Q RGS+PV+W Q     NPR Q+T+  + T+  F+ H  K +E Y    VVNL+     E  +                             +T    F  V  L   I + +    +   D      I  Q G+FR NC+DCLDRTN+ Q  I+    R  +E    I              +  +WA+HGD +S+ Y GT ALK  F+R G+   AG + D   S +R Y+N F D  +Q  ID + G LP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YNL325C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:28739:31378:-1 gene:YNL325C transcript:YNL325C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FIG4 description:Phosphatidylinositol 3,5-bisphosphate (PtdIns[3,5]P) phosphatase; required for efficient mating and response to osmotic shock; physically associates with and regulated by Vac14p; contains a SAC1-like domain; homologous to human FIG4, which is associated with CMT4J, a form of Charcot-Marie-Tooth disorder [Source:SGD;Acc:S000005269]</Hit_def>
  <Hit_accession>YNL325C</Hit_accession>
  <Hit_len>879</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>104.76</Hsp_bit-score>
      <Hsp_score>260</Hsp_score>
      <Hsp_evalue>3.73374e-23</Hsp_evalue>
      <Hsp_query-from>922</Hsp_query-from>
      <Hsp_query-to>1683</Hsp_query-to>
      <Hsp_hit-from>260</Hsp_hit-from>
      <Hsp_hit-to>577</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>91</Hsp_identity>
      <Hsp_positive>135</Hsp_positive>
      <Hsp_gaps>76</Hsp_gaps>
      <Hsp_align-len>324</Hsp_align-len>
      <Hsp_qseq>VALISRRSRHRAGMRYKRRGVDRDGHVANFVETEQLIHIHTHT---------------LSFVQTRGSVPVYWSQAGYTYNPRPQLTKGDKETRDAF----EFHFKKQLEIYQRQVVVNLVDQAGREKIIGDTRGM-KFENVHILTDAICEIISDMK------WCWA-----DAAGLIQ--------------------------VQQGVFRVNCMDCLDRTNVVQAAIARIVMESQLP-------------IKCRRIYQVMWANHGDTVSRQYAGTAALKGDFTRTGERRFAGVMKDGYNSANRYYLNQFRDAYRQAAIDLMQG</Hsp_qseq>
      <Hsp_hseq>ITLIARRSHHFAGARFLKRGVNNKGHVANEVETEQIVTDMILTPFHQPGNGFFDSDRYTSFVQHRGSIPLYWTQDASNLTTKPPIRIN---VVDPFFSPAALHFDNLFQRYGGGTIQILNLIKTKEKTPRETKLLWEFEQC---IDYLNEFLPTLKKLDYTSWDMSRASKQDGQGVIEFLEKYAVNTVTTTGIFHNGPDFASTKIQEGICRSNCIDCLDRTNAAQFVIGKRALGCQLKSLGIIDNSYLEYDSDIVNILTELFHDLGDTIALQYGGSHLVNTMETYRKINQWSSHSRDMIESIKRFYSNSFVDAQRQDAINLFLG</Hsp_hseq>
      <Hsp_midline>+ LI+RRS H AG R+ +RGV+  GHVAN VETEQ++     T                SFVQ RGS+P+YW+Q       +P +        D F      HF    + Y    +  L     +EK   +T+ + +FE      D + E +  +K      W  +     D  G+I+                          +Q+G+ R NC+DCLDRTN  Q  I +  +  QL                   I   ++ + GDT++ QY G+  +    T     +++   +D   S  R+Y N F DA RQ AI+L  G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YIL002C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:350591:353431:-1 gene:YIL002C transcript:YIL002C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:INP51 description:Phosphatidylinositol 4,5-bisphosphate 5-phosphatase; synaptojanin-like protein with an N-terminal Sac1 domain, plays a role in phosphatidylinositol 4,5-bisphosphate homeostasis and in endocytosis; null mutation confers cold-tolerant growth [Source:SGD;Acc:S000001264]</Hit_def>
  <Hit_accession>YIL002C</Hit_accession>
  <Hit_len>946</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.485</Hsp_bit-score>
      <Hsp_score>184</Hsp_score>
      <Hsp_evalue>4.61269e-14</Hsp_evalue>
      <Hsp_query-from>922</Hsp_query-from>
      <Hsp_query-to>1653</Hsp_query-to>
      <Hsp_hit-from>245</Hsp_hit-from>
      <Hsp_hit-to>521</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>124</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>278</Hsp_align-len>
      <Hsp_qseq>VALISRRSRHRAGMRYKRRGVDRDGHVANFVETEQLIHIHTHTLSFVQTRGSVPVYWS--QAGYTYNPRPQLTKGDKETRDAFEFHFKKQLEIYQRQVVVNLV--DQAGREKII------GDTRGMKFENVH----ILTDAICEIISDMK--------WCWADAAGLIQVQQ-GVFRVNCMDCLDRTNVVQAAIARIVME--------SQLPIKCRRIYQVMWANHGDTVSRQYAGTAALKGDFTRTGERRFAGVMKDGYNSANRY---YLNQFRDAY</Hsp_qseq>
      <Hsp_hseq>ITIISRISTESKQDTLELEGISEDGRVSLFVETEIVVTTEKFIFSYTQVNGSIPLFWESVESQLLYGKKIKVTKDSIEAQGAFDRHFDNLTSKYGVVSIVNIIKPKSESQEKLALTYKDCAESKGIKITNIEYSSSVLTKSPHKLLYLLKQDIYEFGAFAYDISRGIYFAKQTGVLRISAFDSIEKPNTVERLVSKEVLELTTNEIDVFELTSPFLDAHDKLWSENYYWLDRTYTKHTKNSGKYTKVYSKLFGSRVR-LYDPLHIYISQYLKQLRSKY</Hsp_hseq>
      <Hsp_midline>+ +ISR S        +  G+  DG V+ FVETE ++       S+ Q  GS+P++W   ++   Y  + ++TK   E + AF+ HF      Y    +VN++      +EK+        +++G+K  N+     +LT +  +++  +K        + +  + G+   +Q GV R++  D +++ N V+  +++ V+E         +L       +  +W+ +   + R Y       G +T+   + F   ++  Y+  + Y   YL Q R  Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2717187603</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052390-RA transcript Note:&quot;Similar to VIM Vimentin (Sus scrofa)&quot; offset:0 AED:0.28 eAED:0.28 QI:0|0|0|0.5|1|1|2|0|347</Iteration_query-def>
  <Iteration_query-len>1044</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>594561019</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052392-RA transcript Note:&quot;Similar to CFAP99 Cilia- and flagella-associated protein 99 (Chlamydomonas reinhardtii)&quot; offset:366 AED:0.03 eAED:0.03 QI:366|0.92|0.93|1|0.64|0.6|15|0|222</Iteration_query-def>
  <Iteration_query-len>1035</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>591617085</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052393-RA transcript Note:&quot;Similar to CFAP99 Cilia- and flagella-associated protein 99 (Homo sapiens)&quot; offset:0 AED:0.03 eAED:0.03 QI:0|0.92|0.93|1|0.64|0.6|15|686|440</Iteration_query-def>
  <Iteration_query-len>2009</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1306707591</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0041575-RA transcript Note:&quot;Similar to RNASEH2C Ribonuclease H2 subunit C (Bos taurus)&quot; offset:383 AED:1.00 eAED:1.00 QI:383|0|0|0|1|1|4|485|144</Iteration_query-def>
  <Iteration_query-len>1303</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>93</Statistics_hsp-len>
      <Statistics_eff-space>784391047</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052396-RA transcript Note:&quot;Similar to NAT8L N-acetylaspartate synthetase (Homo sapiens)&quot; offset:0 AED:0.07 eAED:0.07 QI:0|-1|0|1|-1|1|1|0|142</Iteration_query-def>
  <Iteration_query-len>429</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>81</Statistics_hsp-len>
      <Statistics_eff-space>147526954</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052397-RA transcript Note:&quot;Similar to PRELID1 PRELI domain-containing protein 1, mitochondrial (Gallus gallus)&quot; offset:583 AED:0.15 eAED:0.15 QI:583|0.75|1|1|0.5|0.6|5|475|169</Iteration_query-def>
  <Iteration_query-len>1568</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YLR193C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:540009:540536:-1 gene:YLR193C transcript:YLR193C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:UPS1 description:Phosphatidic acid transfer protein; plays a role in phospholipid metabolism by transporting phosphatidic acid from the outer to the inner mitochondrial membrane; localizes to the mitochondrial intermembrane space; null mutant has altered cardiolipin and phosphatidic acid levels; ortholog of human PRELI [Source:SGD;Acc:S000004183]</Hit_def>
  <Hit_accession>YLR193C</Hit_accession>
  <Hit_len>175</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>1.67284e-12</Hsp_evalue>
      <Hsp_query-from>584</Hsp_query-from>
      <Hsp_query-to>949</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>122</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>125</Hsp_align-len>
      <Hsp_qseq>MVKYYACLGILKSSWDHVFAAFWQRYPNPYSKHVLTEDVLWREVTEDXXXXXXXXXXXXXXXPKWAERLLPSHVAPRHVYILEDSVMDAANQRLITFTRNVNHTRLM---EFGVARFKSNVSKAM</Hsp_qseq>
      <Hsp_hseq>MVLLHKSTHIFPTDFASVSRAFFNRYPNPYSPHVLSIDTISRNVDQEGNLRTTRLLKKSGKLPTWVKPFLRGIT---ETWIIEVSVVNPANSTMKTYTRNLDHTGIMKVEEYTTYQFDSATSSTI</Hsp_hseq>
      <Hsp_midline>MV  +    I  + +  V  AF+ RYPNPYS HVL+ D + R V ++  L T RLL K+ +LP W +  L         +I+E SV++ AN  + T+TRN++HT +M   E+   +F S  S  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>981689476</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052399-RA transcript Note:&quot;Similar to Lrrk1 Leucine-rich repeat serine/threonine-protein kinase 1 (Mus musculus)&quot; offset:0 AED:0.22 eAED:0.68 QI:0|0.04|0.07|0.53|0.96|0.96|26|0|381</Iteration_query-def>
  <Iteration_query-len>1146</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YJL005W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:425157:431237:1 gene:YJL005W transcript:YJL005W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CYR1 description:Adenylate cyclase; required for cAMP production and cAMP-dependent protein kinase signaling; the cAMP pathway controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation [Source:SGD;Acc:S000003542]</Hit_def>
  <Hit_accession>YJL005W</Hit_accession>
  <Hit_len>2026</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.929</Hsp_bit-score>
      <Hsp_score>154</Hsp_score>
      <Hsp_evalue>2.06316e-11</Hsp_evalue>
      <Hsp_query-from>112</Hsp_query-from>
      <Hsp_query-to>498</Hsp_query-to>
      <Hsp_hit-from>870</Hsp_hit-from>
      <Hsp_hit-to>1001</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>70</Hsp_positive>
      <Hsp_gaps>11</Hsp_gaps>
      <Hsp_align-len>136</Hsp_align-len>
      <Hsp_qseq>LKICWIAEISQSIVEM------DLSQNLLEELPPLVPWGLKMLRAFDASSNQLTCFPSVTPQQIFCTGLTEINLSMNCLFSLPAEVFLLTNLKTLNLSHNQLSEFG-CPERADLEVLNLSYNQLGELRKEVLQLLN</Hsp_qseq>
      <Hsp_hseq>LQRNFIRKVPNSIMKLSNLTILNLQCNELESLPAGF-VELKNLQLLDLSSNKFMHYPEVIN---YCTNLLQIDLSYNKIQSLPQSTKYLVKLAKMNLSHNKLNFIGDLSEMTDLRTLNLRYNRISSIKTNASNLQN</Hsp_hseq>
      <Hsp_midline>L+  +I ++  SI+++      +L  N LE LP      LK L+  D SSN+   +P V     +CT L +I+LS N + SLP     L  L  +NLSHN+L+  G   E  DL  LNL YN++  ++     L N</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>673218897</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052400-RA transcript Note:&quot;Similar to Lrrk1 Leucine-rich repeat serine/threonine-protein kinase 1 (Mus musculus)&quot; offset:0 AED:0.48 eAED:0.63 QI:0|0.04|0.07|0.57|1|1|26|337|896</Iteration_query-def>
  <Iteration_query-len>3028</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>84.3445</Hsp_bit-score>
      <Hsp_score>207</Hsp_score>
      <Hsp_evalue>6.17151e-17</Hsp_evalue>
      <Hsp_query-from>691</Hsp_query-from>
      <Hsp_query-to>1512</Hsp_query-to>
      <Hsp_hit-from>1181</Hsp_hit-from>
      <Hsp_hit-to>1436</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>135</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>287</Hsp_align-len>
      <Hsp_qseq>LGQGASGTIYRALY--QGQPVAIKDYHIKGAAQQEDTVLRRMHAGRVWRRMADLRVEACMMRTLSHPCVVALLGVSVRPLV--LMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLS---FGQGSRGSEGTPGYQAPE-VRPGFVFDERVDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLIR----GERPTVPLEAWRHAQPLA-EIMEQCWKTCPKQRPSSHEVVT</Hsp_qseq>
      <Hsp_hseq>IGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEA---------LRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDE----------PLIKHLTTQVLK----GLAYLHSKGILHRDMKADNLL---LDQDGI--CKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSN---LEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANELLS</Hsp_hseq>
      <Hsp_midline>+G+G+ G +Y  L    G+ +A+K   +   + Q + +L  + A         LR E   ++ L H  +V  LG   +  +  L LE    GS+  ++      +           PL   LT +V+      LAYLH  G+LH D+K+DN+L   LD       K++D+G+SR S   +        GT  + APE V     +  +VD++SLG ++ E+ +G+RP      L+VV  + +       P +P +       +    ++ C++  P++RP+++E+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.1889</Hsp_bit-score>
      <Hsp_score>204</Hsp_score>
      <Hsp_evalue>1.23545e-16</Hsp_evalue>
      <Hsp_query-from>694</Hsp_query-from>
      <Hsp_query-to>1377</Hsp_query-to>
      <Hsp_hit-from>553</Hsp_hit-from>
      <Hsp_hit-to>777</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>238</Hsp_align-len>
      <Hsp_qseq>GQGASGTIYRALYQGQP-----VAIKDYHIKGAAQQEDTVLRRMHAGRVWRRMADLRVEACMMRTLSHPCVVALLGVSVRP---LVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGV-SRLSFGQGSRGSE-GTPGYQAPEVRPGFVFDERVDVFSLGMVIYELLSGQRPAVEGRPLDVV</Hsp_qseq>
      <Hsp_hseq>GQGASGSVYLAERTHIPTESNMIELINNDIDEPHVGDKVAIKQMVLSKQPRKELIVN-EILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHS-------PLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVL---LDTRARV--KITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKAL</Hsp_hseq>
      <Hsp_midline>GQGASG++Y A     P     + + +  I      +   +++M   +  R+   +  E  +M+   H  +V  L   +R    L +++E    GSL+D++E     ++S         PL       ++ +    L +LH   ++H D+KSDNVL   LD    V  K+ D+G  +RL+  +  R +  GTP + APEV     +DE++DV+SLG++  E+L G+ P +   PL  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.337</Hsp_bit-score>
      <Hsp_score>194</Hsp_score>
      <Hsp_evalue>5.13011e-16</Hsp_evalue>
      <Hsp_query-from>691</Hsp_query-from>
      <Hsp_query-to>1398</Hsp_query-to>
      <Hsp_hit-from>76</Hsp_hit-from>
      <Hsp_hit-to>281</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>121</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>240</Hsp_align-len>
      <Hsp_qseq>LGQGASGTIY--RALYQGQPVAIKDYHIKGAAQQEDTVLRRMHAGRVWRRMADLRVEACMMRTLSHPCVVALLGV--SVRPLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSEGTPGYQAPEVRPGFVFDERVDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLIRGE</Hsp_qseq>
      <Hsp_hseq>LGTGSFGRVHLVRSVHNGRYYAIK-------------VLKKQQVVKM-KQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRK------SQRFPN----PVAKFYAAEVI----LALEYLHAHNIIYRDLKPENILL-DRNGHI----KITDFGFAK-EVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGK</Hsp_hseq>
      <Hsp_midline>LG G+ G ++  R+++ G+  AIK             VL++    ++ +++     E  M++ + HP ++ + G     R + ++++    G L  +L +      SQ  P+    P+      +VI    LAL YLH H +++ DLK +N+L+   + H+    K+ D+G ++      +    GTP Y APEV     +++ VD +SLG++IYE+L+G  P  +  P+    K+++G+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.337</Hsp_bit-score>
      <Hsp_score>194</Hsp_score>
      <Hsp_evalue>1.2631e-15</Hsp_evalue>
      <Hsp_query-from>640</Hsp_query-from>
      <Hsp_query-to>1476</Hsp_query-to>
      <Hsp_hit-from>345</Hsp_hit-from>
      <Hsp_hit-to>619</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>131</Hsp_positive>
      <Hsp_gaps>56</Hsp_gaps>
      <Hsp_align-len>305</Hsp_align-len>
      <Hsp_qseq>LLLDVASLDYNPREELQL----GQGASGTIYRALYQGQPVAIKDYHIKGAAQQEDTVLRRMHAGRV-WRRMADLRV-------------EACMMRTLSHPCVVALLGVSV---RPLVLMLELAPLGSLSDVLE---RRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVS-RLSFGQGSRGSE-GTPGYQAPEVRPGFVFDERVDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLIRGERPTVPLEAWRHAQPLAEIMEQCWKTC</Hsp_qseq>
      <Hsp_hseq>MKMKTVAIDVNPRPYFQLVEKAGQGASGAVYLSKRIKLP------------QENDPRFLKSHCHRVVGERVAIKQIRLSEQPKKQLIMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSS--------PLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGL-----VKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANNGSPKL-----RHPESVSKQTKQFLDAC</Hsp_hseq>
      <Hsp_midline>+ +   ++D NPR   QL    GQGASG +Y +     P            Q+ D    + H  RV   R+A  ++             E  +M       +V  L   +     L +++E    G L+D+L+   R    EHS         PL       ++ +    L +LH   ++H D+KSDN+L+ S         K+ D+G    L+  +  R +  GTP + APE+     +DE+VDV+SLG+++ E++ G+ P +   PL  +  +     P +     RH + +++  +Q    C</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.9518</Hsp_bit-score>
      <Hsp_score>193</Hsp_score>
      <Hsp_evalue>1.9401e-15</Hsp_evalue>
      <Hsp_query-from>691</Hsp_query-from>
      <Hsp_query-to>1509</Hsp_query-to>
      <Hsp_hit-from>61</Hsp_hit-from>
      <Hsp_hit-to>301</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>81</Hsp_identity>
      <Hsp_positive>139</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>280</Hsp_align-len>
      <Hsp_qseq>LGQGASGTIYRALYQ--GQPVAIKDYHIKGAAQQEDTVLRRMHAGRVWRRMADLRVEACMMRTLSHPCVVALLGV--SVRPLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSR-LSFGQGSRGSEGTPGYQAPEVRPGFVF-DERVDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLIRGERPTVPLEAWRHAQP-LAEIMEQCWKTCPKQRPSSHEVV</Hsp_qseq>
      <Hsp_hseq>LGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSD-------MQGRIEREISYLRL-------LRHPHIIKLYDVIKSKDEIIMVIEYAG-NELFDYIVQRDKM--SEQE------------ARRFFQQIISAVEYCHRHKIVHRDLKPENLL---LDEH--LNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLP-FDDESIPVLFKNISNGVYTLP----KFLSPGAAGLIKRMLIVNPLNRISIHEIM</Hsp_hseq>
      <Hsp_midline>LG+G+ G +  A +   GQ VA+K  + K  A+ +         GR+ R ++ LR+       L HP ++ L  V  S   +++++E A    L D + +R  +  S++E              +   Q+  A+ Y HRH ++H DLK +N+L   LD H  +N K+AD+G+S  ++ G   + S G+P Y APEV  G ++    VDV+S G+++Y +L  + P  +   + V+ K I     T+P    +   P  A ++++     P  R S HE++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.8702</Hsp_bit-score>
      <Hsp_score>185</Hsp_score>
      <Hsp_evalue>2.06197e-14</Hsp_evalue>
      <Hsp_query-from>685</Hsp_query-from>
      <Hsp_query-to>1509</Hsp_query-to>
      <Hsp_hit-from>624</Hsp_hit-from>
      <Hsp_hit-to>866</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>133</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>281</Hsp_align-len>
      <Hsp_qseq>LQLGQGASGTIYRALYQGQPVAIKDYHIKGAAQQEDTVLRRMHAGRVWRRMADLRVEACMMRTLSHPCVVALLGVSVRP--LVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYG----VSRLSFGQGSRGSEGTPGYQAPEVRPGFVFDERVDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLIRGERPTVPLEAWRHAQPLAEIMEQCWKTCPKQRPSSHEVV</Hsp_qseq>
      <Hsp_hseq>VKIGQGASGGVYTAYEIGTNVSV--------------AIKQMNLEKQPKKELIIN-EILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVTHCILTEGQ----------IGA-----VCRETLSGLEFLHSKGVLHRDIKSDNILL-SMEGDI----KLTDFGFCAQINELNLKRTTMV--GTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPPYLNETPLRALYLIATNGTPKL-KEPENLSSSLKKFLDWCLCVEPEDRASATELL</Hsp_hseq>
      <Hsp_midline>+++GQGASG +Y A   G  V++               +++M+  +  ++   +  E  +M+   HP +V  +   V    L +++E    GSL+DV+   +  E            +G      V  +    L +LH  G+LH D+KSDN+L+ S++  +    KL D+G    ++ L+  + +    GTP + APEV     +  +VD++SLG++I E++ G+ P +   PL  +  +     P +  E    +  L + ++ C    P+ R S+ E++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.7146</Hsp_bit-score>
      <Hsp_score>182</Hsp_score>
      <Hsp_evalue>4.2793e-14</Hsp_evalue>
      <Hsp_query-from>820</Hsp_query-from>
      <Hsp_query-to>1509</Hsp_query-to>
      <Hsp_hit-from>492</Hsp_hit-from>
      <Hsp_hit-to>707</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>238</Hsp_align-len>
      <Hsp_qseq>RVWRRMAD-LRVEACMMRTLSHPCVVALLGVSVR--PLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSR----LSFGQGSRGS-EGTPGYQAPEVRPGFVFDERVDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLIRGERPTVPLEAWRHAQPLAEIMEQCWKTCPKQRPSSHEVV</Hsp_qseq>
      <Hsp_hseq>NIHRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEES--------------LITNFTRQILIGVAYLHKKNIIHRDIKGANILI-----DIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKIGTNTTPEIP--SWATSEG-KNFLRKAFELDYQYRPSALELL</Hsp_hseq>
      <Hsp_midline> + R+M D L+ E  +++ L H  +V   G S     L + LE  P GS+S +L      E S              L      Q+ + +AYLH+  ++H D+K  N+L+      +    K+ D+G+S+    L+  Q  R S +G+  + +PEV        + D++S G V+ E+ +G+ P  +   +  + K+     P +P  +W  ++     + + ++   + RPS+ E++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.9442</Hsp_bit-score>
      <Hsp_score>180</Hsp_score>
      <Hsp_evalue>5.2267e-14</Hsp_evalue>
      <Hsp_query-from>688</Hsp_query-from>
      <Hsp_query-to>1347</Hsp_query-to>
      <Hsp_hit-from>205</Hsp_hit-from>
      <Hsp_hit-to>420</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>54</Hsp_gaps>
      <Hsp_align-len>245</Hsp_align-len>
      <Hsp_qseq>QLGQGASGTIYRALYQ--GQPVAIKDYHIKGAAQQEDTVLRRMHAGRVWRRMADLRVEACMMRTLSHPCVVALLGVSVRPL-------VLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLV---------------WSLDPHVAVNAKLADYGVSRLSFG-QGSRGSEGTPGYQAPEVRPGFVFDERVDVFSLGMVIYELLSGQRP</Hsp_qseq>
      <Hsp_hseq>ELGAGHYALVKEAKNKKTGQQVAVKIFH----AQQNDD----------QKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLR--QDESKA------------LFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDED-EIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVILYVCLCGFPP</Hsp_hseq>
      <Hsp_midline>+LG G    +  A  +  GQ VA+K +H    AQQ D            ++    R E  ++  + HP +V LL   V P+        L+LE    G L + + R+  L   Q+E  A            +  Q+   L YLH   ++H D+K +N+L+               W  D  + +  K+AD+G+++ +   Q +    GTP Y APEV     +  +VD++S G+++Y  L G  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.559</Hsp_bit-score>
      <Hsp_score>179</Hsp_score>
      <Hsp_evalue>1.26763e-13</Hsp_evalue>
      <Hsp_query-from>691</Hsp_query-from>
      <Hsp_query-to>1488</Hsp_query-to>
      <Hsp_hit-from>27</Hsp_hit-from>
      <Hsp_hit-to>273</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>281</Hsp_align-len>
      <Hsp_qseq>LGQGASGTIYRALYQ--GQPVAIK-----DYHIKGAAQQEDTVLRRMHAGRVWRRMADLRVEACMMRTLSHPCVVALLGV--SVRPLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQG-SRGSEGTPGYQAPEVRPGFVFDERV-DVFSLGMVIYELLSGQRPAVE--GRPLDVVRKLIRG--ERPTVPLEAWRHAQPLAEIMEQCWKTCPKQR</Hsp_qseq>
      <Hsp_hseq>LGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVL-----------PYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLL------------VDHGPLPEREAIN--CFRQIIIGISYCHALGIVHRDLKPENLLLDSF-----YNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPN-DTEISRDAQ---DLIGKILVVDPRQR</Hsp_hseq>
      <Hsp_midline>LG G++G +  A ++  G   A+K      ++  G    +D+VL             ++  E  +M+ LSHP V++L  V  +   L L+LE A  G L ++L             D  PLP    +      Q+ + ++Y H  G++H DLK +N+L+ S       N K+AD+G++ L         S G+P Y APE+  G  ++    DV+S G++++ LL+G+ P  E  G   D++ K+ +G  E P    E  R AQ   +++ +     P+QR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>1.27349e-13</Hsp_evalue>
      <Hsp_query-from>691</Hsp_query-from>
      <Hsp_query-to>1512</Hsp_query-to>
      <Hsp_hit-from>204</Hsp_hit-from>
      <Hsp_hit-to>462</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>129</Hsp_positive>
      <Hsp_gaps>53</Hsp_gaps>
      <Hsp_align-len>293</Hsp_align-len>
      <Hsp_qseq>LGQGASGTIYRALYQ--GQPVAIKDYHIKGAAQQEDTVLRRMHAGRVWRRMADLRVEACMMRTLSHPCVVALLGV--SVRPLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGS--RGSEGTPGYQAPEVRPGF-------VFDER------VDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLIRGERPTVPLEAWRHAQPLAEIMEQCWKTCPKQRPSSHEVVT</Hsp_qseq>
      <Hsp_hseq>VGQGAFATVKKAIERTTGKTFAVKIISKRKVIGNMDGVTRELE----------------VLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAV--------------GEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDP---VLVKITDFGLAKVQ-GNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGPLKDFRISEEARDFIDSLLQVDPNNRSTAAKALN</Hsp_hseq>
      <Hsp_midline>+GQGA  T+ +A+ +  G+  A+K    +      D V R +                 +++ L+HP +V L G         +++E    G L D +    A+              G     ++  Q+  A+ Y+H  G+ H DLK DN+L+   DP   V  K+ D+G++++  G GS  +   GT  Y APEV  G         ++ER      VD++S+G ++Y +L+G  P        + +++ RG     PL+ +R ++   + ++   +  P  R ++ + + </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.4034</Hsp_bit-score>
      <Hsp_score>176</Hsp_score>
      <Hsp_evalue>2.69949e-13</Hsp_evalue>
      <Hsp_query-from>646</Hsp_query-from>
      <Hsp_query-to>1515</Hsp_query-to>
      <Hsp_hit-from>17</Hsp_hit-from>
      <Hsp_hit-to>273</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>143</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>297</Hsp_align-len>
      <Hsp_qseq>LDVASLDYNPREELQLGQGASGTIYRA--LYQGQPVAIKDYHIKGAAQQEDTVLRRMHAGRVWRRMADL-RVEACMMRTLSHPCVVALLGVSVRPLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGS---RGSEGTPGYQAPEV-RPGFVFDERVDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLIRGERPTVPLEAWRHAQPLAEIMEQCWKTCPKQRPSSHEVVTS</Hsp_qseq>
      <Hsp_hseq>MDVSSLFK--RTEV-IGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTS--------------LWIIMEHCAGGSLRSLL-RPGKIDEKY---------IGVIM-----RELLVALKCIHKDNVIHRDIKAANVLITN-----EGNVKLCDFGVA-AQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIKSKPPR--LEDRSYSTSLKEFIALCLDEDPKERLSADDLLKS</Hsp_hseq>
      <Hsp_midline>+DV+SL    R E+ +G+G  G +Y+   +  G+  AIK  ++   + + + V R +      ++++++ R     ++  S              L +++E    GSL  +L R   ++            +GVI+      ++ +AL  +H+  ++H D+K+ NVL+ +       N KL D+GV+     Q S   +   GTP + APEV   G  +D +VD++SLG+  YE+ +G  P  +   L  ++ +I+ + P   LE   ++  L E +  C    PK+R S+ +++ S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.4774</Hsp_bit-score>
      <Hsp_score>171</Hsp_score>
      <Hsp_evalue>8.62055e-13</Hsp_evalue>
      <Hsp_query-from>853</Hsp_query-from>
      <Hsp_query-to>1509</Hsp_query-to>
      <Hsp_hit-from>129</Hsp_hit-from>
      <Hsp_hit-to>332</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>111</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>231</Hsp_align-len>
      <Hsp_qseq>EACMMRTLSHPCVVALLGV--SVRPLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSE--GTPGYQAPEV----RPGFVFDERVDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLIRGERPTVPLEAWRHAQPLAE----IMEQCWKTCPKQRPSSHEVV</Hsp_qseq>
      <Hsp_hseq>EIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLT----EPEVRFFTT----------QICGAIKYMHSRRVIHRDLKLGNIFFDS-----NYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFE--VDIWSLGVMLYALLIG-KPPFQARDVNTIYERIKCRDFSFPRD-----KPISDEGKILIRDILSLDPIERPSLTEIM</Hsp_hseq>
      <Hsp_midline>E  + +++SHP +V  +        + ++LE+ P GSL ++L+RR  L     EP+                Q+  A+ Y+H   ++H DLK  N+   S       N K+ D+G++ +   +  R     GTP Y APEV      G  F+  VD++SLG+++Y LL G +P  + R ++ + + I+    + P +     +P+++    ++       P +RPS  E++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>1.01146e-12</Hsp_evalue>
      <Hsp_query-from>691</Hsp_query-from>
      <Hsp_query-to>1512</Hsp_query-to>
      <Hsp_hit-from>24</Hsp_hit-from>
      <Hsp_hit-to>268</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>126</Hsp_positive>
      <Hsp_gaps>43</Hsp_gaps>
      <Hsp_align-len>281</Hsp_align-len>
      <Hsp_qseq>LGQGASGTIYRAL--YQGQPVAIKDYHIKGAAQQEDTVLRRMHAGRVWRRMADLRVEACMMRTLSHPCVVALLGVSVRPLVL--MLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGS-EGTPGYQAPEVRPGFV--FDERVDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLIRGERPTVPLEAWRHAQPLAEIMEQCWKTCPKQRPSSHEVVT</Hsp_qseq>
      <Hsp_hseq>IGRGNFGDVYKAVDRVTQEIVAIKVVNLEHS--DEDIEL--------------LAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEK------------VSFIIHEVTLGLKYLHEQRKIHRDIKAANIL---LNEEGMV--KLGDFGVSGHIRSTLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPPLSKYDPMKVMTNLPKRKPPKL---QGPFSDAAKDFVAGCLVKTPADRPSAYNLLS</Hsp_hseq>
      <Hsp_midline>+G+G  G +Y+A+     + VAIK  +++ +   ED  L              L  E   +  L  P +   +   +  + +  ++E    GS SD+L+R       +E+               +IH++ L L YLH    +H D+K+ N+L   L+    V  KL D+GVS        R +  GTP + APEV    V  ++E+ D++SLG+  YELL G  P  +  P+ V+  L + + P +       +    + +  C    P  RPS++ +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>1.8472e-12</Hsp_evalue>
      <Hsp_query-from>853</Hsp_query-from>
      <Hsp_query-to>1668</Hsp_query-to>
      <Hsp_hit-from>81</Hsp_hit-from>
      <Hsp_hit-to>353</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>79</Hsp_identity>
      <Hsp_positive>137</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>296</Hsp_align-len>
      <Hsp_qseq>EACMMRTLSHPCVVALLGV--SVRPLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRL-SFGQGSRGSEGTPGYQAPEVRPGFVFDERV-DVFSLGMVIYELLSGQRPAVE--GRPLDVVRKLIRG--ERPTVPLEAWRHAQPLAEIMEQCWKTCPKQRPSSHEVVT--------SLCDPTSAC-----QAYSVECGQHNACLPCSAFPRHALLWYG---DGILSVLTVPSGHMQ</Hsp_qseq>
      <Hsp_hseq>EIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVER------------GPLPEHEAI--RFFRQIIIGVSYCHALGIVHRDLKPENLLL----DH-KYNIKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDD-EISREAQDL---IRKILTVDPERRIKTRDILKHPLLQKYPSIRDSKSIRGLPREDTYLTPLSESNSSIDATILQNLVILWHGRDPEGIKEKLREPGANAE</Hsp_hseq>
      <Hsp_midline>E  +M+ L+HP V+ L  V  +   L L+LE A  G L ++L  R             PLP    +  +   Q+ + ++Y H  G++H DLK +N+L+     H   N K+AD+G++ L + G+    S G+P Y APE+  G  +     DV+S G++++ LL+G+ P  E  G    ++ K+ +G  E P+   E  R AQ L   + +     P++R  + +++         S+ D  S         Y     + N+ +  +      +LW+G   +GI   L  P  + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.3218</Hsp_bit-score>
      <Hsp_score>168</Hsp_score>
      <Hsp_evalue>2.80957e-12</Hsp_evalue>
      <Hsp_query-from>691</Hsp_query-from>
      <Hsp_query-to>1527</Hsp_query-to>
      <Hsp_hit-from>1040</Hsp_hit-from>
      <Hsp_hit-to>1308</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>136</Hsp_positive>
      <Hsp_gaps>62</Hsp_gaps>
      <Hsp_align-len>305</Hsp_align-len>
      <Hsp_qseq>LGQGASGTIYRA--LYQGQPVAIKDYHIKGAAQQEDTVLRRMHAGRVWRRMADLRVEACMMRTLSHPCVVALLGVSVR--PLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSR----------GSE--------GTPGYQAPEVRPGFVFDERV---DVFSLGMVIYELLSGQRP-AVEGRPLDVVRKLIRGERPTVPLEAWRHAQPLAEIMEQCWKTCPKQRPSSHEVVTSLCDP</Hsp_qseq>
      <Hsp_hseq>IGGGTFGQVYSAINLENGEILAVKEIKI-----HDTTTMKKIFPL--------IKEEMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEYCEGGSLASLLD------HGRIEDE--------MVTQVYTFELLEGLAYLHQSGVVHRDIKPENIL---LDFNGII--KYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPWSNLDNEWAIMYHVAAGRIPQLPNRDEMTAAGRA-FLERCLVQDPTMRATAVEL---LIDP</Hsp_hseq>
      <Hsp_midline>+G G  G +Y A  L  G+ +A+K+  I      + T ++++           ++ E  ++  L+HP +V   GV V    + + +E    GSL+ +L+      H + E +        ++T     ++   LAYLH+ G++H D+K +N+L   LD +  +  K  D+G +R   G  +R          G E        GTP Y APE   G     ++   DV++LG V+ E+ +G+RP +       ++  +  G  P +P      A   A  +E+C    P  R ++ E+   L DP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>3.04845e-12</Hsp_evalue>
      <Hsp_query-from>670</Hsp_query-from>
      <Hsp_query-to>1488</Hsp_query-to>
      <Hsp_hit-from>23</Hsp_hit-from>
      <Hsp_hit-to>313</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>141</Hsp_positive>
      <Hsp_gaps>60</Hsp_gaps>
      <Hsp_align-len>312</Hsp_align-len>
      <Hsp_qseq>NPREELQLGQGASGTIYRALY---QGQPVAIKDYHIKGAAQQEDTVLRRMHAGRVWRRMADLRVEACMMRTLSHPCVVALLGV--SVRPLVLMLELAPLGSLSDVLERRVALEHS--------QEEP----DADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNA------------------KLADYGVSRLSFGQGSRGSE---GTPGYQAPEVRPGFVFDERVDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLIRGERPTVPLEAWRHAQP-LAEIMEQCWKTCPKQR</Hsp_qseq>
      <Hsp_hseq>NYTAEKEIGKGSFATVYRGHLTSDKSQHVAIKE--VSRAKLKNKKLLE------------NLEIEIAILKKIKHPHIVGLIDCERTSTDFYLIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSY--LQQLASALKFLRSKNLVHRDIKPQNLLLST--PLIGYHDSKSFHELGFVGIYNLPILKIADFGFAR--FLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVVFEMCCGTPPFRASNHLELFKKIKRA-NDVITFPSYCNIEPELKELICSLLTFDPAQR</Hsp_hseq>
      <Hsp_midline>N   E ++G+G+  T+YR      + Q VAIK+  +  A  +   +L             +L +E  +++ + HP +V L+    +     L++E   LG L+ +L+RR  L  +        ++ P    + + L    +L++  + Q+  AL +L    ++H D+K  N+L+ +  P +  +                   K+AD+G +R  F   +  +E   G+P Y APE+     ++ + D++S+G V++E+  G  P      L++ +K+ R     +   ++ + +P L E++       P QR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>5.08637e-12</Hsp_evalue>
      <Hsp_query-from>691</Hsp_query-from>
      <Hsp_query-to>1509</Hsp_query-to>
      <Hsp_hit-from>31</Hsp_hit-from>
      <Hsp_hit-to>267</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>278</Hsp_align-len>
      <Hsp_qseq>LGQGASGTIYRAL--YQGQPVAIKDYHIKGAAQQEDTVLRRMHAGRVWRRMADLRVEACMMRTLSHPCVVALLGVSVRP--LVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSEGTPGYQAPEVRPGFVFDERVDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLIRGERPT-VPLEAWRHAQPLAEIMEQCWKTCPKQRPSSHEVV</Hsp_qseq>
      <Hsp_hseq>IGRGSYGVVYKAINKHTDQVVAIKE-----VVYEND------------EELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENE-------------SKTYVTQTLLGLKYLHGEGVIHRDIKAANILL-SADNTV----KLADFGVSTI-VNSSALTLAGTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNPPYHNLTDANIYYAV---ENDTYYPPSSF--SEPLKDFLSKCFVKNMYKRPTADQLL</Hsp_hseq>
      <Hsp_midline>+G+G+ G +Y+A+  +  Q VAIK+        + D              + D+  E  +++ L+H  +V   G   +   L ++LE    GSL  ++ R        E             +   + Q  L L YLH  G++H D+K+ N+L+ S D  V    KLAD+GVS +     +    GT  + APE+          D++SLG  + E+L+   P       ++   +   E  T  P  ++  ++PL + + +C+     +RP++ +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>6.11913e-12</Hsp_evalue>
      <Hsp_query-from>691</Hsp_query-from>
      <Hsp_query-to>1527</Hsp_query-to>
      <Hsp_hit-from>1272</Hsp_hit-from>
      <Hsp_hit-to>1556</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>136</Hsp_positive>
      <Hsp_gaps>78</Hsp_gaps>
      <Hsp_align-len>321</Hsp_align-len>
      <Hsp_qseq>LGQGASGTIYRA--LYQGQPVAIKDYHIKGAAQQEDTVLRRMHAGRVWRRMADLRVEACMMRTLSHPCVVALLGVSVR--PLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSE----------------------------------GTPGYQAPEVRPGFVFDERV---DVFSLGMVIYELLSGQRP-AVEGRPLDVVRKLIRGERPTVPLEAWRHAQPLAEIMEQCWKTCPKQRPSSHEVVTSLCDP</Hsp_qseq>
      <Hsp_hseq>IGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQ-------------KIFPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLA------ALLEHGRIEDE--------MVTQVYTLQLLEGLAYLHESGIVHRDVKPENIL---LDFNGVI--KYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPWANLDNEWAIMYHVAAGHTPQFPTKDEVSSAGM-KFLERCLIQNPSKRASAVEL---LMDP</Hsp_hseq>
      <Hsp_midline>+G G  G +Y A  L  G+ +A+K+ +I+ +   +             +    ++ E  ++  L+HP +V+  GV V    + + +E    GSL+        LEH + E +        ++T     Q+   LAYLH  G++H D+K +N+L   LD +  +  K  D+G ++     G+R +                                   GTP Y APE   G     ++   DV+SLG V+ E+++G+RP A       ++  +  G  P  P +    +  + + +E+C    P +R S+ E+   L DP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>1.1855e-11</Hsp_evalue>
      <Hsp_query-from>691</Hsp_query-from>
      <Hsp_query-to>1398</Hsp_query-to>
      <Hsp_hit-from>93</Hsp_hit-from>
      <Hsp_hit-to>298</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>114</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>240</Hsp_align-len>
      <Hsp_qseq>LGQGASGTIY--RALYQGQPVAIKDYHIKGAAQQEDTVLRRMHAGRVWRRMADLRVEACMMRTLSHPCVVALLGV--SVRPLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSEGTPGYQAPEVRPGFVFDERVDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLIRGE</Hsp_qseq>
      <Hsp_hseq>LGTGSFGRVHLIRSRHNGRYYAMK-------------VLKKEIVVRL-KQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRK------SQRFPN----PVAKFYAAEVC----LALEYLHSKDIIYRDLKPENIL---LDKNGHI--KITDFGFAKY-VPDVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAE</Hsp_hseq>
      <Hsp_midline>LG G+ G ++  R+ + G+  A+K             VL++    R+ +++     E  M+  ++HP ++ + G     + + ++++    G L  +L +      SQ  P+    P+      +V     LAL YLH   +++ DLK +N+L   LD +  +  K+ D+G ++      +    GTP Y APEV     +++ +D +S G++IYE+L+G  P  +   +    K++  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>1.8666e-11</Hsp_evalue>
      <Hsp_query-from>688</Hsp_query-from>
      <Hsp_query-to>1509</Hsp_query-to>
      <Hsp_hit-from>196</Hsp_hit-from>
      <Hsp_hit-to>461</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>289</Hsp_align-len>
      <Hsp_qseq>QLGQGASGTIYRALY--QGQPVAIKDYHIKGAAQQEDTVLRRMHAGRVWRRMADLRVEACMMRTLSHPCVVALLGVSVR-----PLVLMLELAPLGSLSDVLE--RRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHR-HGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSEGTPGYQAPEVRPGFVFDERVDVFSLGMVIYELLSGQRP--AVEGRP---LDVVRKLIRGERPTVPLEAWRHAQPLAEIMEQCWKTCPKQRPSSHEVV</Hsp_qseq>
      <Hsp_hseq>KIGAGNSGTVVKALHVPDSKIVAKKTIPVE---QNNSTIINQL-----------VRELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILSVYKRFV---QRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINS-----KGQIKLCDFGVSKKLINSIADTFVGTSTYMSPERIQGNVYSIKGDVWSLGLMIIELVTGEFPLGGHNDTPDGILDLLQRIVNEPSPRLPKDRI-YSKEMTDFVNRCCIKNERERSSIHELL</Hsp_hseq>
      <Hsp_midline>++G G SGT+ +AL+    + VA K   ++   Q   T++ ++           +R  + +     H  ++   G          +++++E +  GSL  +L   +R      +    +       +   K+ + +   L +L+R + ++H D+K  NVL+ S         KL D+GVS+      +    GT  Y +PE   G V+  + DV+SLG++I EL++G+ P       P   LD++++++    P +P +   +++ + + + +C     ++R S HE++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>3.5551e-11</Hsp_evalue>
      <Hsp_query-from>1042</Hsp_query-from>
      <Hsp_query-to>1398</Hsp_query-to>
      <Hsp_hit-from>289</Hsp_hit-from>
      <Hsp_hit-to>436</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>148</Hsp_align-len>
      <Hsp_qseq>LTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLV--------------WSLDPHVAVN---------------AKLADYGVSRLSFGQGSRGSEGTPGYQAPEVRPGFVFDERVDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLIRGE</Hsp_qseq>
      <Hsp_hseq>LSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKNTKTPCGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTMLCGFPPFYDEKIDTLTEKISRGE</Hsp_hseq>
      <Hsp_midline>L+  VI Q+ LA+ ++H  G++H D+K +N+L                S DP    +                KLAD+G+S+  F + ++   GT GY APEV     +  +VD++ +G V+Y +L G  P  + +   +  K+ RGE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>8.22729e-11</Hsp_evalue>
      <Hsp_query-from>1027</Hsp_query-from>
      <Hsp_query-to>1488</Hsp_query-to>
      <Hsp_hit-from>198</Hsp_hit-from>
      <Hsp_hit-to>343</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>157</Hsp_align-len>
      <Hsp_qseq>PLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNA--KLADYGVSRLSFGQGSRGSE-GTPGYQAPEVRPGFVFDERVDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLIRGERPTVPLEAWRHAQPLAEIMEQCWKTCPKQR</Hsp_qseq>
      <Hsp_hseq>PFNDILASDYIYQIANALDYMHKKNIIHRDIKPENIL-------IGFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGA-PPFEEEMKDTTYKRIAALDIKMPSNISQDAQ---DLILKLLKYDPKDR</Hsp_hseq>
      <Hsp_midline>P   IL    I+Q+  AL Y+H+  ++H D+K +N+L       +  N   KL D+G S ++  +  R +  GT  Y +PE+     +D  +D ++LG++ +ELL+G  P  E    D   K I      +P    + AQ   +++ +  K  PK R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>9.59724e-11</Hsp_evalue>
      <Hsp_query-from>688</Hsp_query-from>
      <Hsp_query-to>1398</Hsp_query-to>
      <Hsp_hit-from>126</Hsp_hit-from>
      <Hsp_hit-to>372</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>114</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>263</Hsp_align-len>
      <Hsp_qseq>QLGQGASGTIYRAL----YQGQPVAIKDYHIKGAAQQEDTVLR---RMHAGRVWRRMADLRVEACMMRTLSHPCVVALLGVSVRPLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLV-----WSLDPHV--------------AVNAKLADYGVSRLSFGQGSRGSEGTPGYQAPEVRPGFVFDERVDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLIRGE</Hsp_qseq>
      <Hsp_hseq>KIGEGAFSRVFKAVGINTDDQAPVAIKAIIKKGISS--DAILKGNDRIQGSSRKKVLNEVAIHKLVSKNNPHCTKFIAFQESANYYYLVTELVTGG---EIFDRIVQLTCFSED-----------LARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLRNNTAKTPCGTIEYVASEVFTSKRYSMKVDMWSIGCVLFTLLCGYPPFYEKNEKTLLKKISRGD</Hsp_hseq>
      <Hsp_midline>++G+GA   +++A+        PVAIK    KG +   D +L+   R+      + + ++ +   + +   H         S     L+ EL   G   ++ +R V L    E+           L   VI Q+ +A+ ++H  G++H D+K +N+L      + LD  +                  KL D+G+++      ++   GT  Y A EV     +  +VD++S+G V++ LL G  P  E     +++K+ RG+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>1.39295e-10</Hsp_evalue>
      <Hsp_query-from>796</Hsp_query-from>
      <Hsp_query-to>1416</Hsp_query-to>
      <Hsp_hit-from>104</Hsp_hit-from>
      <Hsp_hit-to>305</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>222</Hsp_align-len>
      <Hsp_qseq>VLRRMHAGRVW-------------RRMADLRVEACMMRTLSHPCVVALLGV--SVRPLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSEGTPGYQAPEVRPGFVFDERVDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLIRGERPTVPL</Hsp_qseq>
      <Hsp_hseq>LIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRK------SQRFPN----PVAKFYAAEVC----LALEYLHSKDIIYRDLKPENIL---LDKNGHI--KITDFGFAKY-VPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPF</Hsp_hseq>
      <Hsp_midline>++R  H GR +             +++     E  M+  +SHP ++ + G     + + ++++    G L  +L +      SQ  P+    P+      +V     LAL YLH   +++ DLK +N+L   LD +  +  K+ D+G ++      +    GTP Y APEV     +++ VD +S G++IYE+L+G  P      +     ++  E    P </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>2.52864e-10</Hsp_evalue>
      <Hsp_query-from>691</Hsp_query-from>
      <Hsp_query-to>1347</Hsp_query-to>
      <Hsp_hit-from>21</Hsp_hit-from>
      <Hsp_hit-to>221</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>234</Hsp_align-len>
      <Hsp_qseq>LGQGASGTIYRALYQGQP---VAIKDYHIKGAAQQEDTVLRRMHAGRVWRRMADLRVEACMMRTLS-HPCVVALL--GVSVRPLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRH-GMLHCDLKSDNVLVWSLDPHVAVNAKLADYGV-SRLSFGQG----SRGSEGTPGYQAPEV---RPGFVFDERVDVFSLGMVIYELLSGQRP</Hsp_qseq>
      <Hsp_hseq>VGQGAFACVKNAHLQMDPSIILAVKFIHVPTC--------KKMGLSD-----KDITKEVVLQSKCSKHPNVLRLIDCNVSKEYMWIILEMADGGDLFDKIEPDVGV-------DSD-------VAQFYFQQLVSAINYLHVECGVAHRDIKPENIL---LDKNG--NLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGY-YADRTDIWSIGILLFVLLTGQTP</Hsp_hseq>
      <Hsp_midline>+GQGA   +  A  Q  P   +A+K  H+           ++M          D+  E  +    S HP V+ L+   VS   + ++LE+A  G L D +E  V +       D+D       +      Q+  A+ YLH   G+ H D+K +N+L   LD +   N KLAD+G+ S+     G    S    G+P Y APEV     G+ + +R D++S+G++++ LL+GQ P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.003</Hsp_bit-score>
      <Hsp_score>149</Hsp_score>
      <Hsp_evalue>4.23793e-10</Hsp_evalue>
      <Hsp_query-from>1072</Hsp_query-from>
      <Hsp_query-to>1419</Hsp_query-to>
      <Hsp_hit-from>935</Hsp_hit-from>
      <Hsp_hit-to>1046</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>118</Hsp_align-len>
      <Hsp_qseq>LALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSE--GTPGYQAPEVRPGFVFDERVDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLIRGERPTVPLE</Hsp_qseq>
      <Hsp_hseq>LALKYFHDNGVIYRDLKLENILL-TPEGHI----KIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSP-FSGDDEDEVFNAILTDEPLYPID</Hsp_hseq>
      <Hsp_midline>LAL Y H +G+++ DLK +N+L+ + + H+    K+ADYG+ +     G+R S   GTP + APE+     + + VD ++ G+++Y++L  Q P   G   D V   I  + P  P++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YKL116C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:221344:222900:-1 gene:YKL116C transcript:YKL116C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR1 description:Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]</Hit_def>
  <Hit_accession>YKL116C</Hit_accession>
  <Hit_len>518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>5.09598e-10</Hsp_evalue>
      <Hsp_query-from>691</Hsp_query-from>
      <Hsp_query-to>1347</Hsp_query-to>
      <Hsp_hit-from>198</Hsp_hit-from>
      <Hsp_hit-to>444</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>66</Hsp_gaps>
      <Hsp_align-len>266</Hsp_align-len>
      <Hsp_qseq>LGQGASGTI--YRALYQGQP----VAIKDYHIK---GAAQQEDTVLRRMHAGRVWRRMADLRVEACMMRTLSHPCVVALLGV-------SVRPLV--------------LMLELAPLGSL-SDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLV-WSLDPHVAVNA-------------KLADYGV-SRLSFGQGSRGSEGTPGYQAPEVRPGFVFDERV-DVFSLGMVIYELLSGQRP</Hsp_qseq>
      <Hsp_hseq>IGSGNFSTVLLYELMDQSNPKLKQVAVKRLKYPEELSNVEQINTSLR--YKETLSRLENSLTRELQVLKSLNHPCIVKLLGINNPIFVTSKKPLCDLIIKTPRALPPCDMIMSYCPAGDLLAAVMARNGRLE--------------AWLIQRIFTEVVLAVKYLHENSIIHRDLKLENILLKYSFD---DINSFRDSPIYCKQNFIELADFGLCKKIENNEMCTARCGSEDYVSPEILMGVPYDGHLSDTWALGVILYSLFEDRLP</Hsp_hseq>
      <Hsp_midline>+G G   T+  Y  + Q  P    VA+K           +Q +T LR  +   + R    L  E  ++++L+HPC+V LLG+       S +PL               +++   P G L + V+ R   LE                L  ++  ++ LA+ YLH + ++H DLK +N+L+ +S D    +N+             +LAD+G+  ++   +      G+  Y +PE+  G  +D  + D ++LG+++Y L   + P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>4.01252e-09</Hsp_evalue>
      <Hsp_query-from>829</Hsp_query-from>
      <Hsp_query-to>1416</Hsp_query-to>
      <Hsp_hit-from>194</Hsp_hit-from>
      <Hsp_hit-to>385</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>211</Hsp_align-len>
      <Hsp_qseq>RRMADLRVEACMMRTLSHPCVVALLGV--SVRPLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSE------------GTPGYQAPEVRPGFVFDERVDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLIRGER-PTVPL</Hsp_qseq>
      <Hsp_hseq>KRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGEL---------FYHLKEHGTLDETTVSFYAA-----EISCALRFLHTKGVVYRDLKPENCLL-NQRGHLV----LTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIPF</Hsp_hseq>
      <Hsp_midline>+R+     E  ++  + HP +V L         L L+L+  P G L           H +E    D   +          ++  AL +LH  G+++ DLK +N L+ +   H+     L D+G+S+ S    +   E            GTP Y APE+  G  + +  D +SLG ++Y++L G+ P        ++ K+ + ++ P +P </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>5.07146e-09</Hsp_evalue>
      <Hsp_query-from>691</Hsp_query-from>
      <Hsp_query-to>1359</Hsp_query-to>
      <Hsp_hit-from>53</Hsp_hit-from>
      <Hsp_hit-to>256</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>233</Hsp_align-len>
      <Hsp_qseq>LGQGASGTIY--RALYQGQPVAIKDYHIKGAAQQEDTVLRRMHAGRVWRRMADLRVEACMMRTLSHPCVVALLG--VSVRPLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGS--RGSEGTPGYQAPEVRPGFVFDERVDVFSLGMVIYELLSGQRP----AVEG</Hsp_qseq>
      <Hsp_hseq>LGAGSFGVVRQARKLSTNEDVAIK-ILLKKALQGNNVQLQMLYE------------ELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFD----RILSRGKFTEVDA----------VEIIVQILGAVEYMHSKNVVHRDLKPENVLY--VDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSPFIAESVEG</Hsp_hseq>
      <Hsp_midline>LG G+ G +   R L   + VAIK   +K A Q  +  L+ ++             E  +++ LSHP +V+      S     ++ +LA  G L D    R+       E DA           ++I Q+  A+ Y+H   ++H DLK +NVL   +D        +AD+G+++   G+      + G+ GY APEV       +  D++S+G++ Y LL G  P    +VEG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.8398</Hsp_bit-score>
      <Hsp_score>133</Hsp_score>
      <Hsp_evalue>1.57868e-08</Hsp_evalue>
      <Hsp_query-from>838</Hsp_query-from>
      <Hsp_query-to>1338</Hsp_query-to>
      <Hsp_hit-from>41</Hsp_hit-from>
      <Hsp_hit-to>218</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>190</Hsp_align-len>
      <Hsp_qseq>ADLRVEACMMRTLS----HPCVVALLGVSVRP--LVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSEGTPGYQAPEVRPGFV--------FDE---------RVDVFSLGMVIYELLSG</Hsp_qseq>
      <Hsp_hseq>ANMKNEYDVMKILSSCNPHPNICSMLDFYTDDSYYIMVLEYCECGDLYDFLD----IAKSQGSPSSPSLIQ--IDMQKIIKQLCSAISFAHSLGIAHRDIKPENILL-----TINGDIKLADWGHAIQS-PKSNDFQIGTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFG</Hsp_hseq>
      <Hsp_midline>A+++ E  +M+ LS    HP + ++L         +++LE    G L D L+    +  SQ  P +  L    I   K+I Q+  A+++ H  G+ H D+K +N+L+      +  + KLAD+G +  S  + +    GT  Y+APE   G V        FD          + D +SLG  I+ L+ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>2.08077e-08</Hsp_evalue>
      <Hsp_query-from>634</Hsp_query-from>
      <Hsp_query-to>1329</Hsp_query-to>
      <Hsp_hit-from>423</Hsp_hit-from>
      <Hsp_hit-to>646</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>244</Hsp_align-len>
      <Hsp_qseq>KRLLLDVASLDYNPREEL--------QLGQGASGTIYRALYQGQPVAIKDYHIKGAAQQEDTVLRRMHAGRVWRRMADLRVEACMMRTLSHPCVVALLGV--SVRPLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRH-GMLHCDLKSDNVLVWSLDPHVAVNAKLADYGV-SRLSFGQGSRGSEGTPGYQAPEVRPGFVFDERVDVFSLGMVIYEL</Hsp_qseq>
      <Hsp_hseq>KRRLISSNKLSANPDSHLFEKFTNVHSIGKGQFSTVYQVTFAQ---TNKKYAIKAIKPNKYNSLKRI---LLEIKILNEVTNQITMDQEGKEYIIDYISSWKFQNSYYIMTELCENGNLDGFLQEQVIAKKKR---------LEDWRIWKIIVELSLALRFIHDSCHIVHLDLKPANVMI-----TFEGNLKLGDFGMATHLPLEDKSFENEGDREYIAPEIISDCTYDYKADIFSLGLMIVEI</Hsp_hseq>
      <Hsp_midline>KR L+    L  NP   L         +G+G   T+Y+  +       K Y IK     +   L+R+    +  ++ +       M       ++  +          +M EL   G+L   L+ +V  +  +         L      K+I ++ LAL ++H    ++H DLK  NV++         N KL D+G+ + L     S  +EG   Y APE+     +D + D+FSLG++I E+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YHR079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:258244:261591:-1 gene:YHR079C transcript:YHR079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IRE1 description:Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; role in homeostatic adaptation to ER stress; Kar2p binds inactive Ire1p and releases from it upon ER stress [Source:SGD;Acc:S000001121]</Hit_def>
  <Hit_accession>YHR079C</Hit_accession>
  <Hit_len>1115</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>2.28623e-08</Hsp_evalue>
      <Hsp_query-from>691</Hsp_query-from>
      <Hsp_query-to>1509</Hsp_query-to>
      <Hsp_hit-from>680</Hsp_hit-from>
      <Hsp_hit-to>975</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>83</Hsp_identity>
      <Hsp_positive>143</Hsp_positive>
      <Hsp_gaps>87</Hsp_gaps>
      <Hsp_align-len>328</Hsp_align-len>
      <Hsp_qseq>LGQGASGTI-YRALYQGQPVAIKDYHIKGAAQQEDTVLRRMHAGRVWRRMADLRVEACMMRTLS--HPCVVALL--GVSVRPLVLMLELAPLGSLSDVLE-RRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLV-----WSLDPHV-AVNAK--LADYGV-SRLSFGQGS-----RGSEGTPGYQAPEV------------------RPGFV--------FDER-----VDVFSLGMVIYELLS-GQRPAVEGRPLDVVRKLIRGERPTVPLEAWRHAQPLAE---IMEQCWKTCPKQRPSSHEVV</Hsp_qseq>
      <Hsp_hseq>LGYGSSGTVVFQGSFQGRPVAVK---------------------RMLIDFCDIALMEIKLLTESDDHPNVIRYYCSETTDRFLYIALELCNL-NLQDLVESKNVSDENLKLQKEYNPISL--------LRQIASGVAHLHSLKIIHRDLKPQNILVSTSSRFTADQQTGAENLRILISDFGLCKKLDSGQSSFRTNLNNPSGTSGWRAPELLEESNNLQCQVETEHSSSRHTVVSSDSFYDPFTKRRLTRSIDIFSMGCVFYYILSKGKHPF--GDKYSRESNIIRGIFSLDEMKCLHDRSLIAEATDLISQMIDHDPLKRPTAMKVL</Hsp_hseq>
      <Hsp_midline>LG G+SGT+ ++  +QG+PVA+K                     R+     D+ +    + T S  HP V+       + R L + LEL  L +L D++E + V+ E+ + + + +P+ L        + Q+   +A+LH   ++H DLK  N+LV     ++ D    A N +  ++D+G+  +L  GQ S         GT G++APE+                  R   V        F +R     +D+FS+G V Y +LS G+ P   G        +IRG      ++       +AE   ++ Q     P +RP++ +V+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>2.46926e-08</Hsp_evalue>
      <Hsp_query-from>829</Hsp_query-from>
      <Hsp_query-to>1347</Hsp_query-to>
      <Hsp_hit-from>219</Hsp_hit-from>
      <Hsp_hit-to>388</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>43</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>189</Hsp_align-len>
      <Hsp_qseq>RRMADLRVEACMMRTLSH-PCVVALLGV--SVRPLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRL-------------SFGQGSRGSEGTPGYQAPEVRPGFVFDERVDVFSLGMVIYELLSGQRP</Hsp_qseq>
      <Hsp_hseq>KKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDET--------------CARYYAAQIIDAIDYLHSNGIIHRDIKPENIL---LDGEMKI--KLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPP</Hsp_hseq>
      <Hsp_midline>+++  + +E   ++ L++ P VV L         L  +LE AP G    ++++  +L+ +                     Q+  A+ YLH +G++H D+K +N+L   LD  + +  KL D+G ++L                  S+   GT  Y +PE+      D R D+++ G +++++++G+ P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>7.44843e-08</Hsp_evalue>
      <Hsp_query-from>793</Hsp_query-from>
      <Hsp_query-to>1389</Hsp_query-to>
      <Hsp_hit-from>144</Hsp_hit-from>
      <Hsp_hit-to>324</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>206</Hsp_align-len>
      <Hsp_qseq>TVLRRMHAGRVWRRMADLRVEACMMRTLSHPCVVALLGV--SVRPLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIH---QMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSF-GQGSRGSEGTPGYQAPEVRPGFVFDER-VDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLI</Hsp_qseq>
      <Hsp_hseq>SIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYL-----------------VSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRI----KIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFND----DNIKKLL</Hsp_hseq>
      <Hsp_midline>++  R H+         +  E  +M+ +SH  V+AL  V  +   L L+LE    G L D L                 +  G +   + IH   Q+   ++Y H   + H DLK +N+L+   +  +    K+AD+G++ L    +  + S G+P Y +PE+  G  +     DV+S G+V++ LL+G  P  +    D ++KL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>7.56434e-08</Hsp_evalue>
      <Hsp_query-from>688</Hsp_query-from>
      <Hsp_query-to>1404</Hsp_query-to>
      <Hsp_hit-from>16</Hsp_hit-from>
      <Hsp_hit-to>248</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>261</Hsp_align-len>
      <Hsp_qseq>QLGQGASGTIYRALYQGQPVAIKDYHIKGAAQQEDTVLRRMHAGRVWRRMADLRVEACMMRTLS---HPCVVALLGV--SVRPLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVL--------VWSLDPHVAVNAKLADYGVSRLSFGQGSRGSE------GTPGYQAPEVRPGFVFDE---RVDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLIRGERP</Hsp_qseq>
      <Hsp_hseq>ELGHGSYSTVFKALDKKSPNKI--YAIKVCSKKH--IIKEAKVKYV-------TIEKNTMNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFND--------------IWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPEL---LLYNQCGYGSDIWALGCMIYQFVQGQPPFRGENELKTFEKIVALDYP</Hsp_hseq>
      <Hsp_midline>+LG G+  T+++AL +  P  I  Y IK  +++   +++      V        +E   M  L+   H  ++ L         L  +L+ AP G L  +L +                    I T     Q+  AL ++H HG++H DLK +NVL        +        ++  L+       S   GS+ ++      GT  Y +PE+    ++++     D+++LG +IY+ + GQ P      L    K++  + P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>8.80208e-08</Hsp_evalue>
      <Hsp_query-from>664</Hsp_query-from>
      <Hsp_query-to>1362</Hsp_query-to>
      <Hsp_hit-from>25</Hsp_hit-from>
      <Hsp_hit-to>220</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>238</Hsp_align-len>
      <Hsp_qseq>DYNPREELQLGQGASGTIYRAL--YQGQPVAIKDYHIKGAAQQEDTVLRRMHAGRVWRRMADLRVEACMMRTLSHPCVVALLGVSVRPLVLMLELAPL--GSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSEGTPGYQAPEVRPGF-VFDERVDVFSLGMVIYELLSGQRPAVEGR</Hsp_qseq>
      <Hsp_hseq>DLNP-----VGMGAFGLVCSATDTLTSQPVAIK----KIMKPFSTAVL----AKRTYRELK-------LLKHLRHENLICLQDIFLSPLEDIYFVTELQGTDLHRLLQTR---------------PLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILI-----NENCDLKICDFGLARIQDPQMT-GYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEG-KPLFPGK</Hsp_hseq>
      <Hsp_midline>D NP     +G GA G +  A      QPVAIK    K        VL    A R +R +        +++ L H  ++ L  + + PL  +  +  L    L  +L+ R               PL        ++Q+   L Y+H  G++H DLK  N+L+     +   + K+ D+G++R+   Q + G   T  Y+APE+   +  +D  VD++S G +  E++ G +P   G+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>9.20977e-08</Hsp_evalue>
      <Hsp_query-from>688</Hsp_query-from>
      <Hsp_query-to>1389</Hsp_query-to>
      <Hsp_hit-from>12</Hsp_hit-from>
      <Hsp_hit-to>221</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>242</Hsp_align-len>
      <Hsp_qseq>QLGQGASGTIYRALYQ--GQPVAIKDYHIKGAAQQEDTVLRRMHAGRVWRRMADLRVEACMMRTLSHPCVVALLGV--SVRPLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFG--QGSRGSE-GTPGYQAPEVRPGF-VFDERVDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLI</Hsp_qseq>
      <Hsp_hseq>KLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIR----------------EISLMKELKHENIVRLYDVIHTENKLTLVFEFMD-NDLKKYMDSRTV--------GNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLI-----NKRGQLKLGDFGLAR-AFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITG-KPLFPGTNDEEQLKLI</Hsp_hseq>
      <Hsp_midline>+LG G   T+Y+ L +  G  VA+K+  +        T +R                E  +M+ L H  +V L  V  +   L L+ E      L   ++ R             P  L + L      Q+   LA+ H + +LH DLK  N+L+     +     KL D+G++R +FG    +  SE  T  Y+AP+V  G   +   +D++S G ++ E+++G +P   G   +   KLI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>1.10335e-07</Hsp_evalue>
      <Hsp_query-from>688</Hsp_query-from>
      <Hsp_query-to>1392</Hsp_query-to>
      <Hsp_hit-from>13</Hsp_hit-from>
      <Hsp_hit-to>226</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>248</Hsp_align-len>
      <Hsp_qseq>QLGQGASGTIYRALY----QGQPV-AIKDYHIKGAAQQEDTVLRRMHAGRVWRRMADLRVEACMMRTLSHPCVVALLGV---SVRPLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSEG---TPGYQAPEV-RPGFVFDERVDVFSLGMVIYELLSGQRPAVEG-RPLDVVRKLIR</Hsp_qseq>
      <Hsp_hseq>KVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIR---------------EISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDL----DLKRYMEGIPKDQ--------PLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLI-----NKDGNLKLGDFGLAR-AFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCN-RKPIFSGDSEIDQIFKIFR</Hsp_hseq>
      <Hsp_midline>++G+G  G +Y+AL     QGQ V A+K   ++   +   +   R               E  +++ L    +V L  +       L L+ E   L    D+      +   Q        PLG  +  K + Q+   +AY H H +LH DLK  N+L+     +   N KL D+G++R +FG   R       T  Y+APEV   G  +   VD +S+G +  E+ + ++P   G   +D + K+ R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YDR247W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:956013:957398:1 gene:YDR247W transcript:YDR247W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VHS1 description:Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; VHS1 has a paralog, SKS1, that arose from the whole genome duplication [Source:SGD;Acc:S000002655]</Hit_def>
  <Hit_accession>YDR247W</Hit_accession>
  <Hit_len>461</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.1434</Hsp_bit-score>
      <Hsp_score>126</Hsp_score>
      <Hsp_evalue>1.50344e-07</Hsp_evalue>
      <Hsp_query-from>688</Hsp_query-from>
      <Hsp_query-to>1533</Hsp_query-to>
      <Hsp_hit-from>17</Hsp_hit-from>
      <Hsp_hit-to>335</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>129</Hsp_positive>
      <Hsp_gaps>85</Hsp_gaps>
      <Hsp_align-len>343</Hsp_align-len>
      <Hsp_qseq>QLGQGASGTIYRALYQGQPVAIKDYHIK------GAAQQEDTVLRRMHAG--RVWRRMADLRVEA--------------------------------CMMRTLSHPCVVALLGV--SVRPLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSEGTPGYQAPEVRPGFVFDERV-------------------DVFSLGMVIYELLSGQRPAVEGRPLDVVRKLIRGERPTVPLEAWRHAQPLAEIMEQCWKTCPKQRPSSHEVVTSLCDPTS</Hsp_qseq>
      <Hsp_hseq>QIGEGAYGLVYRAL---DIRTDRQYAIKAVVQSYGVSKEADMGNDKIHKNSVKLQKKLAKLFKESKNVVRVPSIDLESIENMSEEDFKKLPHYKEISLHLRVHHHKNIVTIHEVLQSAVCTFIVMDYYPTDLFTSIVDNRHFVTNG-------------LLVKKVFLQICSALNYCHEHGIYHCDIKPENLLLDTED-----NVFLCDFGLSTTSTYIKPNVCIGSSYYMPPE---RISFDGRVSSSKSGGHKLGKVCPSCNGDLWSLGIILINLTCIRNPWLKADKTEDNTYYYFTKDPNILKQILPLSDDFYSLLSKILQVNPKNRMSLQELMKEVSSITS</Hsp_hseq>
      <Hsp_midline>Q+G+GA G +YRAL        + Y IK      G +++ D    ++H    ++ +++A L  E+                                  +R   H  +V +  V  S     ++++  P    + +++ R  + +              +L  KV  Q+  AL Y H HG+ HCD+K +N+L+ + D     N  L D+G+S  S         G+  Y  PE      FD RV                   D++SLG+++  L   + P ++    +        + P +  +    +     ++ +  +  PK R S  E++  +   TS</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>1.84759e-07</Hsp_evalue>
      <Hsp_query-from>1054</Hsp_query-from>
      <Hsp_query-to>1362</Hsp_query-to>
      <Hsp_hit-from>133</Hsp_hit-from>
      <Hsp_hit-to>236</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>111</Hsp_align-len>
      <Hsp_qseq>VIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSEG-------TPGYQAPEVRPGFV-FDERVDVFSLGMVIYELLSGQRPAVEGR</Hsp_qseq>
      <Hsp_hseq>FIYQILCALKYIHSANVLHCDLKPKNLLVNS-----DCQLKICNFGLS-CSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELL-GRKPMFEGK</Hsp_hseq>
      <Hsp_midline> I+Q+  AL Y+H   +LHCDLK  N+LV S         K+ ++G+S  S+ +  + ++G       +  Y+APE+   +    + VD++S G ++ ELL G++P  EG+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>2.15218e-07</Hsp_evalue>
      <Hsp_query-from>853</Hsp_query-from>
      <Hsp_query-to>1347</Hsp_query-to>
      <Hsp_hit-from>211</Hsp_hit-from>
      <Hsp_hit-to>384</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>187</Hsp_align-len>
      <Hsp_qseq>EACMMRTLSHPCVVALLGVSV---RPLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSE--GTPGYQAPEV-----RPGFV------------FDERVDVFSLGMVIYELLSGQRP</Hsp_qseq>
      <Hsp_hseq>EARILLRLDHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETE-----------SLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRI--VLADFGIAKDLNSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGISP</Hsp_hseq>
      <Hsp_midline>EA ++  L HP ++ +          L +  +L P G L   L +   L    E             +  ++ Q+  AL YLH   ++H DLK DN+L+ + +P   +   LAD+G+++       R     GTP Y APEV     R  +             +D + D++SLG++ + +L+G  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>2.26964e-07</Hsp_evalue>
      <Hsp_query-from>1075</Hsp_query-from>
      <Hsp_query-to>1392</Hsp_query-to>
      <Hsp_hit-from>457</Hsp_hit-from>
      <Hsp_hit-to>559</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>62</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>108</Hsp_align-len>
      <Hsp_qseq>ALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSE--GTPGYQAPEVRPGFVFDERVDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLIR</Hsp_qseq>
      <Hsp_hseq>ALDNLHKLDVVYRDLKPENILL-DYQGHIA----LCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQ</Hsp_hseq>
      <Hsp_midline>AL  LH+  +++ DLK +N+L+     H+A    L D+G+ +L+     +     GTP Y APE+  G  + + VD ++LG+++YE+L+G  P  +     + +K+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>2.40177e-07</Hsp_evalue>
      <Hsp_query-from>1024</Hsp_query-from>
      <Hsp_query-to>1512</Hsp_query-to>
      <Hsp_hit-from>315</Hsp_hit-from>
      <Hsp_hit-to>484</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>175</Hsp_align-len>
      <Hsp_qseq>LPLGVILTHKVIHQMGLA----LAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSEGTPGYQAPEVRPGFVFDERVDVFSLGMVIYELLSGQRP------AVEGRPLDVVRKLIRG--ERPTVPLEAWRHAQPLAEIMEQCWKTCPKQRPSSHEVVT</Hsp_qseq>
      <Hsp_hseq>LERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILL-----NENGQVKLCDFGVSGEAVNSLATTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANGKFPCSSEKMAANIAPFELLMWILTFTPELKDEPESNIIWSPSFKSFIDYCLKKDSRERPSPRQMIN</Hsp_hseq>
      <Hsp_midline>L  G  ++ KV+ ++  A    L+YLH   ++H D+K  N+L+     +     KL D+GVS  +    +    GT  Y APE   G  +    DV+SLG+ I E+ +G+ P      A    P +++  ++    E    P      +      ++ C K   ++RPS  +++ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>2.64166e-07</Hsp_evalue>
      <Hsp_query-from>1057</Hsp_query-from>
      <Hsp_query-to>1356</Hsp_query-to>
      <Hsp_hit-from>448</Hsp_hit-from>
      <Hsp_hit-to>544</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>32</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>102</Hsp_align-len>
      <Hsp_qseq>IHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSE--GTPGYQAPEVRPGFVFDERVDVFSLGMVIYELLSGQRPAVE</Hsp_qseq>
      <Hsp_hseq>IAELLCALDSLHKLDVIYRDLKPENILL-DYQGHIA----LCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYD</Hsp_hseq>
      <Hsp_midline>I ++  AL  LH+  +++ DLK +N+L+     H+A    L D+G+ +L+     +     GTP Y APE+  G  + + VD ++LG+++YE+++G  P  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>3.0291e-07</Hsp_evalue>
      <Hsp_query-from>991</Hsp_query-from>
      <Hsp_query-to>1392</Hsp_query-to>
      <Hsp_hit-from>148</Hsp_hit-from>
      <Hsp_hit-to>290</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>67</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>149</Hsp_align-len>
      <Hsp_qseq>EHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSE------------GTPGYQAPEV---RPGFVFDERVDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLIR</Hsp_qseq>
      <Hsp_hseq>ENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLISS-----NGTVKISDFGVA-MSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPFNANSGLELFDSIIN</Hsp_hseq>
      <Hsp_midline>E+  E     P  L    + KV+  +   L YLH  G+ H D+K  N+L+ S         K++D+GV+ +S   GS   +            GTP + APE+      +     +D++SLG+ IY LL G+ P      L++   +I </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YKL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:347214:349136:-1 gene:YKL048C transcript:YKL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ELM1 description:Serine/threonine protein kinase; regulates the orientation checkpoint, the morphogenesis checkpoint and the metabolic switch from fermentative to oxidative metabolism by phosphorylating the activation loop of Kin4p, Hsl1p and Snf4p respectively; cooperates with Hsl7p in recruiting Hsl1p to the septin ring, a prerequisite for subsequent recruitment, phosphorylation, and degradation of Swe1p; forms part of the bud neck ring; regulates cytokinesis [Source:SGD;Acc:S000001531]</Hit_def>
  <Hit_accession>YKL048C</Hit_accession>
  <Hit_len>640</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>3.05585e-07</Hsp_evalue>
      <Hsp_query-from>1042</Hsp_query-from>
      <Hsp_query-to>1389</Hsp_query-to>
      <Hsp_hit-from>235</Hsp_hit-from>
      <Hsp_hit-to>367</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>137</Hsp_align-len>
      <Hsp_qseq>LTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLS--------------FGQGSRGSEGTPGYQAPEV------RPGFVFDE-RVDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLI</Hsp_qseq>
      <Hsp_hseq>FAKKILEDMTKGLEYLHSQGCIHRDIKPSNIL---LDEEEKV-AKLSDFGSCIFTPQSLPFSDANFEDCFQRELNKIVGTPAFIAPELCHLGNSKRDFVTDGFKLDIWSLGVTLYCLLYNELPFFGENEFETYHKII</Hsp_hseq>
      <Hsp_midline>   K++  M   L YLH  G +H D+K  N+L   LD    V AKL+D+G    +              F +      GTP + APE+      +  FV D  ++D++SLG+ +Y LL  + P       +   K+I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>7.69369e-07</Hsp_evalue>
      <Hsp_query-from>853</Hsp_query-from>
      <Hsp_query-to>1347</Hsp_query-to>
      <Hsp_hit-from>100</Hsp_hit-from>
      <Hsp_hit-to>251</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>79</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>171</Hsp_align-len>
      <Hsp_qseq>EACMMRTLSHPCVVALLGV--SVRPLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGS--RGSEGTPGYQAPE--VRPGFVFDERVDVFSLGMVIYELLSGQRP</Hsp_qseq>
      <Hsp_hseq>EINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESS--------------ACRLFAQLISGVNYMHYKGLVHRDLKLENLL---LDKH--ENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLP</Hsp_hseq>
      <Hsp_midline>E   ++ L+HP ++ L  V  + + + ++LE    G     ++R+  L+ S                 ++  Q+   + Y+H  G++H DLK +N+L   LD H   N  + D+G     F      + S G+P Y APE  V        + DV+S G+++Y +L+G  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>7.8835e-07</Hsp_evalue>
      <Hsp_query-from>796</Hsp_query-from>
      <Hsp_query-to>1347</Hsp_query-to>
      <Hsp_hit-from>81</Hsp_hit-from>
      <Hsp_hit-to>251</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>91</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>190</Hsp_align-len>
      <Hsp_qseq>VLRRMHAGRVWRRMADLRVEACMMRTLSHPCVVALLGV--SVRPLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSR--LSFGQGSRGSEGTPGYQAPE-VRPGFVFDER-VDVFSLGMVIYELLSGQRP</Hsp_qseq>
      <Hsp_hseq>LIKRDSISNDYRKEVKIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKE--------------MNACRLFSQLISGVHYIHSKGLVHRDLKLENLL---LDKN--ENLVITDFGFVNEFCSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLP</Hsp_hseq>
      <Hsp_midline>+++R      +R+   +  E   ++ LSHP +V L  V  + R + ++LE A  G     ++++  L+               +   ++  Q+   + Y+H  G++H DLK +N+L   LD +   N  + D+G      S  +  + S G+P Y APE V     ++ R  D++S G+++Y +L+G  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>1.11116e-06</Hsp_evalue>
      <Hsp_query-from>1063</Hsp_query-from>
      <Hsp_query-to>1518</Hsp_query-to>
      <Hsp_hit-from>140</Hsp_hit-from>
      <Hsp_hit-to>316</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>183</Hsp_align-len>
      <Hsp_qseq>QMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSE-GTPGYQAPEVRPGFVFDE-RVDVFSLGMVIYELLSG------------------QRPAVEGRPL-DVVRKLIR-------GERPTVPLEAWRHA--QPLAE-IMEQCWKTCPKQRPSSHEVVTSL</Hsp_qseq>
      <Hsp_hseq>QISGAVYYAHSMHCVHRDLKLENIL---LDKNG--NAKLTDFGFTRECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDAKVIPDDARDLISRLLAKNPGERPSLS-QVLRHPFLQPYGSVVLDQTQKILCRQRSGGTQFKSKL</Hsp_hseq>
      <Hsp_midline>Q+  A+ Y H    +H DLK +N+L   LD +   NAKL D+G +R    + +  +  GT  Y APE+     +D  ++D++SLG+++Y L++G                  + P  + + + D  R LI        GERP++  +  RH   QP    +++Q  K   +QR    +  + L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>1.2605e-06</Hsp_evalue>
      <Hsp_query-from>982</Hsp_query-from>
      <Hsp_query-to>1509</Hsp_query-to>
      <Hsp_hit-from>290</Hsp_hit-from>
      <Hsp_hit-to>476</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>195</Hsp_align-len>
      <Hsp_qseq>VALEH----SQEEPDADPLPLGVILTHKVIHQMGLA----LAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSEGTPGYQAPEVRPGFVFDERVDVFSLGMVIYELLSGQRPAVEGR------PLDVVRKLIR-----GERPTVPLEAWRHAQPLAEIMEQCWKTCPKQRPSSHEVV</Hsp_qseq>
      <Hsp_hseq>IAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILL-----NEKGEIKLCDFGVSGEAVNSLAMTFTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRFPFESDKITQNVAPIELLTMILTFSPQLKDEPELDI-SW--SKTFRSFIDYCLKKDARERPSPRQML</Hsp_hseq>
      <Hsp_midline>+A+E+    S E    + L  G  ++ +VI ++  +    L+YLH   ++H D+K  N+L+     +     KL D+GVS  +    +    GT  Y APE   G  +    DV+SLG+ + E+  G+ P    +      P++++  ++       + P + + +W  ++     ++ C K   ++RPS  +++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>49.6766</Hsp_bit-score>
      <Hsp_score>117</Hsp_score>
      <Hsp_evalue>1.48517e-06</Hsp_evalue>
      <Hsp_query-from>691</Hsp_query-from>
      <Hsp_query-to>1572</Hsp_query-to>
      <Hsp_hit-from>43</Hsp_hit-from>
      <Hsp_hit-to>308</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>75</Hsp_identity>
      <Hsp_positive>125</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>302</Hsp_align-len>
      <Hsp_qseq>LGQGASGTIYRA--LYQGQPVAIKDYHIKGAAQQEDTVLRRMHAGRVWRRMADLRVEACMMRTLSHPCVVALLG--VSVRPLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSR--LSFGQGSRGSEGTPGYQAPEVRPGFVFDERVDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLIRGERP-TVPLEAWRHAQPLA-EIMEQCWKTCPKQRPSSHEVVTSLCDPTSACQAYSVECGQHN</Hsp_qseq>
      <Hsp_hseq>LGAGTFGVVRQAKNTETGEDVAVK-ILIKKALKGNKVQLEALYD------------ELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFD----RILKKGKFTEEDA----------VRILVEILSAVKYMHSQNIVHRDLKPENLLY--IDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAEL---LEDPWIIC----TELKTHN</Hsp_hseq>
      <Hsp_midline>LG G  G + +A     G+ VA+K   IK A +     L  ++             E  +++ L HP +VA      S     ++ +LA  G L D    R+  +    E DA           +++ ++  A+ Y+H   ++H DLK +N+L   +D        +AD+G+++   S  +      G+ GY APEV       +  D++S+G++ Y LL G       R  D + +   GE P       W      A + + +     P +RP++ E+   L DP   C     E   HN</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.9062</Hsp_bit-score>
      <Hsp_score>115</Hsp_score>
      <Hsp_evalue>4.19965e-06</Hsp_evalue>
      <Hsp_query-from>922</Hsp_query-from>
      <Hsp_query-to>1347</Hsp_query-to>
      <Hsp_hit-from>199</Hsp_hit-from>
      <Hsp_hit-to>336</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>157</Hsp_align-len>
      <Hsp_qseq>LVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSEGTP---------------GYQAPEVRPGFVFDERVDVFSLGMVIYELLSGQRP</Hsp_qseq>
      <Hsp_hseq>LYFLLEYAPHGDFLGLIKKYGSLNET--------------CARYYASQIIDAVDSLHNIGIIHRDIKPENIL---LDKNMKV--KLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPP</Hsp_hseq>
      <Hsp_midline>L  +LE AP G    ++++  +L  +                     Q+  A+  LH  G++H D+K +N+L   LD ++ V  KL D+G +++   + S  ++G P                Y +PE+      D R D+++ G ++Y++L+G+ P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.521</Hsp_bit-score>
      <Hsp_score>114</Hsp_score>
      <Hsp_evalue>5.2226e-06</Hsp_evalue>
      <Hsp_query-from>1057</Hsp_query-from>
      <Hsp_query-to>1398</Hsp_query-to>
      <Hsp_hit-from>519</Hsp_hit-from>
      <Hsp_hit-to>628</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>60</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>117</Hsp_align-len>
      <Hsp_qseq>IHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSEGTPGYQAPEV---RPGFVFDERVDVFSLGMVIYELLSGQRPAVEGRPLDVVRKLIRGE</Hsp_qseq>
      <Hsp_hseq>IAELVLALEHLHDNDIVYRDLKPENILL-----DANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLLDETGYT--KMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGK</Hsp_hseq>
      <Hsp_midline>I ++ LAL +LH + +++ DLK +N+L+         N  L D+G+S+      +    GT  Y APE+     G+   + VD +SLG++I+E+  G  P        + +K+  G+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YPL026C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:500675:502183:-1 gene:YPL026C transcript:YPL026C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKS1 description:Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway; SKS1 has a paralog, VHS1, that arose from the whole genome duplication [Source:SGD;Acc:S000005947]</Hit_def>
  <Hit_accession>YPL026C</Hit_accession>
  <Hit_len>502</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>7.31033e-06</Hsp_evalue>
      <Hsp_query-from>1039</Hsp_query-from>
      <Hsp_query-to>1347</Hsp_query-to>
      <Hsp_hit-from>161</Hsp_hit-from>
      <Hsp_hit-to>274</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>54</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>119</Hsp_align-len>
      <Hsp_qseq>ILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSEGTPGYQAPE--------VRPGFVFDE--------RVDVFSLGMVIYELLSGQRP</Hsp_qseq>
      <Hsp_hseq>ILIKKVFLQLCSALDHCHRLGIYHCDIKPENVLLDRND-----NAYLCDFGLSTKSKYLAPNVCVGSSYYMAPERILYCLNTTTNGIHVDECCSSLPTDTGDIWSLGIILINLTCIRNP</Hsp_hseq>
      <Hsp_midline>IL  KV  Q+  AL + HR G+ HCD+K +NVL+   D     NA L D+G+S  S         G+  Y APE           G   DE          D++SLG+++  L   + P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>7.38593e-06</Hsp_evalue>
      <Hsp_query-from>685</Hsp_query-from>
      <Hsp_query-to>1335</Hsp_query-to>
      <Hsp_hit-from>187</Hsp_hit-from>
      <Hsp_hit-to>376</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>LQLGQGASGTIYRALYQGQPVAIKDYHIKGAAQQEDTVLR--RMHAGRVWRRMADLRVEACMMRTLSHPCVVALLGVSV---RPLVLMLELAPLGSLSDVLERRVALEHSQEEPDADPLPLGVILTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSEG-TPGYQAPEVRPGFV-FDERVDVFSLGMVIYELLS</Hsp_qseq>
      <Hsp_hseq>MQVGEGTYGKVYKA--------------KNTNTEKLVALKKLRLQGEREGFPITSIR-EIKLLQSFDHPNVSTIKEIMVESQKTVYMIFEYADNDLSGLLLNKEVQISHSQ--------------CKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDN-----QGNLKITDFGLARKMNSRADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFN</Hsp_hseq>
      <Hsp_midline>+Q+G+G  G +Y+A              K    ++   L+  R+   R    +  +R E  ++++  HP V  +  + V   + + ++ E A       +L + V + HSQ                 +  Q+ L + YLH + +LH D+K  N+L+ +       N K+ D+G++R    +    +   T  Y+ PE+  G   +   VD++  G ++ EL +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>2057206970</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052402-RA transcript Note:&quot;Similar to Immt MICOS complex subunit Mic60 (Mus musculus)&quot; offset:167 AED:0.21 eAED:0.22 QI:167|0.75|0.76|1|0.83|0.84|13|0|661</Iteration_query-def>
  <Iteration_query-len>2153</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1409797540</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052404-RA transcript Note:&quot;Similar to Stk32b Serine/threonine-protein kinase 32B (Mus musculus)&quot; offset:0 AED:0.40 eAED:0.40 QI:0|0.75|0.66|0.88|1|1|9|0|306</Iteration_query-def>
  <Iteration_query-len>921</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>151.754</Hsp_bit-score>
      <Hsp_score>382</Hsp_score>
      <Hsp_evalue>1.02928e-41</Hsp_evalue>
      <Hsp_query-from>13</Hsp_query-from>
      <Hsp_query-to>744</Hsp_query-to>
      <Hsp_hit-from>429</Hsp_hit-from>
      <Hsp_hit-to>705</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>90</Hsp_identity>
      <Hsp_positive>147</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>284</Hsp_align-len>
      <Hsp_qseq>VQKRDTRTMYAMKYMNKQVCIERDEVRNVFRELQIM---QELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEH-----------------------------APEMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWRPYEIHSSTTIDEILQILDTKSVHYS-SCWSQEMASLLRKLLCLKPKNRWASLA---RVQGSPLLADVNWEAVLQKKVTPSFLPN----KGQLNCDPTF</Hsp_qseq>
      <Hsp_hseq>VKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLLDET----GYTKMVDFWSLGVLIFEMCCGWSPFFAENN---QKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFADIDWEALKQKKIPPPFKPHLVSETDTSNFDPEF</Hsp_hseq>
      <Hsp_midline>V+K+DT+ +YAMK ++K+V ++++E+ +   E  I+         F+V L +SFQ   D+++V D + GG+L +HLQ+  RF E+  + Y+ EL LAL++L    I++RD+KP+NILLD +                             APE+          Y+  VD+WSLGV  +E+  GW P+   ++    ++ Q +    V +     SQE  S ++ LL   PK+R  ++     ++  P  AD++WEA+ QKK+ P F P+        N DP F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>134.806</Hsp_bit-score>
      <Hsp_score>338</Hsp_score>
      <Hsp_evalue>2.68827e-37</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>711</Hsp_query-to>
      <Hsp_hit-from>84</Hsp_hit-from>
      <Hsp_hit-to>343</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>81</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>263</Hsp_align-len>
      <Hsp_qseq>VCIVQKRDTRTMYAMKYMNKQVCIERDEVRNVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEHA-----------------------PEMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWRPYEIHSSTTIDEILQILDTKSVHYSSCWSQEMASLLRKLLCLKPKNRWASLAR----VQGSPLLADVNWEAVLQKKVTPSFLP</Hsp_qseq>
      <Hsp_hseq>VHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPF--YDTTPMKTYEKILQGKVV-YPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEP</Hsp_hseq>
      <Hsp_midline>V +V+       YA+K + KQ  ++  +V +   E ++++ +EH FL+ +W +FQD  ++FMV+D + GG+L   L++S RF     + Y  E+ LAL+YL   +II+RD+KP+NILLD +                        P+     V     Y+ +VDWWSLGV  YE+L G+ P+  + +T +    +IL  K V Y   +  ++  LL KL+      R  +L      ++  P  ++V WE +L K +   + P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>132.494</Hsp_bit-score>
      <Hsp_score>332</Hsp_score>
      <Hsp_evalue>3.02682e-36</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>735</Hsp_query-to>
      <Hsp_hit-from>101</Hsp_hit-from>
      <Hsp_hit-to>368</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>136</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>271</Hsp_align-len>
      <Hsp_qseq>VCIVQKRDTRTMYAMKYMNKQVCIERDEVRNVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEHA-----------------------PEMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWRPYEIHSSTTIDEILQILDTKSVHYSSCWSQEMASLLRKLLCLKPKNRWASLAR----VQGSPLLADVNWEAVLQKKVTPSFLPNKGQLNCD</Hsp_qseq>
      <Hsp_hseq>VHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPF--YDSNTMKTYEKILNAE-LRFPPFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGD</Hsp_hseq>
      <Hsp_midline>V +++ R     YAMK + K++ +   +V +   E  ++  + H F++ +W +FQD + +FM++D + GG+L   L++S RF     + Y  E+ LAL+YL  + II+RD+KP+NILLD++                        P+     V     Y+ ++DWWS G+  YE+L G+ P+  + S T+    +IL+ + + +   +++++  LL +L+      R  +L      V+  P   +V WE +L + +   + P   Q   D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>129.798</Hsp_bit-score>
      <Hsp_score>325</Hsp_score>
      <Hsp_evalue>3.26127e-35</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>711</Hsp_query-to>
      <Hsp_hit-from>102</Hsp_hit-from>
      <Hsp_hit-to>361</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>131</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>263</Hsp_align-len>
      <Hsp_qseq>VCIVQKRDTRTMYAMKYMNKQVCIERDEVRNVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEHA-----------------------PEMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWRPYEIHSSTTIDEILQILDTKSVHYSSCWSQEMASLLRKLLCLKPKNRWASLAR----VQGSPLLADVNWEAVLQKKVTPSFLP</Hsp_qseq>
      <Hsp_hseq>VHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPF--YNSNTMKTYENILNAE-LKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEP</Hsp_hseq>
      <Hsp_midline>V +++       YA+K + K   ++  +V +   E +++  + H F++ +W +FQD + +FMV+D + GG+L   L++S RF     + Y  E+ LAL+YL  + II+RD+KP+NILLD++                        P+     V     Y+ +VDWWS GV  YE+L G+ P+  ++S T+     IL+ + + +   +  +   LL+KL+      R  +L      V+  P   +V WE +L + +   + P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>127.487</Hsp_bit-score>
      <Hsp_score>319</Hsp_score>
      <Hsp_evalue>2.35897e-33</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>711</Hsp_query-to>
      <Hsp_hit-from>358</Hsp_hit-from>
      <Hsp_hit-to>618</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>124</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>265</Hsp_align-len>
      <Hsp_qseq>VCIVQKRDTRTMYAMKYMNKQVCIERDEVRNVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEHA--------------------------PEMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWRP-YEIHSSTTIDEILQILDTKSVHYSSCWSQEMASLLRKLLCLKPKNRWA--SLARVQGSPLLADVNWEAVLQKKVTPSFLP</Hsp_qseq>
      <Hsp_hseq>VMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQ----QPLLFPDGFDPAAKDLLIGLLSRDPSRRLGVNGTDEIRNHPFFKDISWKKLLLKGYIPPYKP</Hsp_hseq>
      <Hsp_midline>V  V+K+DT+ +YA+K + K   + + EV +   E  ++  ++  F+V L +SFQ  E +++V+  + GG+L YHLQ   RF     R Y+ EL  ALD L +  +I+RD+KP+NILLD                             PE     +     Y+  VDWW+LG+  YE++ G  P Y+ +      +ILQ    + + +   +      LL  LL   P  R        ++  P   D++W+ +L K   P + P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>127.102</Hsp_bit-score>
      <Hsp_score>318</Hsp_score>
      <Hsp_evalue>3.42993e-33</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>711</Hsp_query-to>
      <Hsp_hit-from>361</Hsp_hit-from>
      <Hsp_hit-to>621</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>126</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>265</Hsp_align-len>
      <Hsp_qseq>VCIVQKRDTRTMYAMKYMNKQVCIERDEVRNVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEHA--------------------------PEMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWRPYEIHSSTTI-DEILQILDTKSVHYSSCWSQEMASLLRKLLCLKPKNR--WASLARVQGSPLLADVNWEAVLQKKVTPSFLP</Hsp_qseq>
      <Hsp_hseq>VMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQ----EPLVFPDGFDRDAKDLLIGLLSRDPTRRLGYNGADEIRNHPFFSQLSWKRLLMKGYIPPYKP</Hsp_hseq>
      <Hsp_midline>V  V+K+DT+ +YA+K + K   + + EV +   E  ++  ++  F+V L +SFQ  E ++ V+  + GG+L YHLQ+  RF     R Y  EL  ALD L +  +++RD+KP+NILLD                             PE     +     Y+ AVDWW+LGV  YE+L G  PY       +  +ILQ    + + +   + ++   LL  LL   P  R  +     ++  P  + ++W+ +L K   P + P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>107.842</Hsp_bit-score>
      <Hsp_score>268</Hsp_score>
      <Hsp_evalue>1.28316e-26</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>750</Hsp_query-to>
      <Hsp_hit-from>338</Hsp_hit-from>
      <Hsp_hit-to>632</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>83</Hsp_identity>
      <Hsp_positive>137</Hsp_positive>
      <Hsp_gaps>52</Hsp_gaps>
      <Hsp_align-len>298</Hsp_align-len>
      <Hsp_qseq>VCIVQKRDTRTMYAMKYMNKQVCIERDEVRNVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQ--QSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEHA------------------PEM--------------FR--SYVEG----APR------YSSAVDWWSLGVTAYELLRGWRPYEIHSSTTIDEILQILDTKSVHYSSCWSQEMASLLRKLLCLKPKNRWAS---LARVQGSPLLADVNWEAVLQKKVTPSFLPNKGQLNCDPTFEL</Hsp_qseq>
      <Hsp_hseq>VYLVRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKFPHDKEV-SKNCKDLIKKLLNKNEAKRLGSKSGAADIKRHPFFKKVQWSFL--RNQDPPLIPALNDNGCELPFIL</Hsp_hseq>
      <Hsp_midline>V +V++RDT  ++A+K +NK   I+R +++ V  E +I+   +H F+V L++SFQ ++ +++ ++  +GG+    LQ  +S    EE  + Y  E+  AL+YL     I+RD+KP+NILL +                    P M              FR  S+V      AP       +++AVDWW+LG+  YE+L G  P++  +S      +   D K  H     S+    L++KLL      R  S    A ++  P    V W  +  +   P  +P      C+  F L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>105.145</Hsp_bit-score>
      <Hsp_score>261</Hsp_score>
      <Hsp_evalue>1.38453e-25</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>711</Hsp_query-to>
      <Hsp_hit-from>838</Hsp_hit-from>
      <Hsp_hit-to>1102</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>122</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>269</Hsp_align-len>
      <Hsp_qseq>VCIVQKRDTRTMYAMKYMNKQVCIERDEVRNVFRELQIM---QELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILL---------------DE-----------HAPEMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWRPYEIHSSTTIDEILQILDTKSVHYSSCWSQEMASLLRKLLCLKPKNRWASLAR----VQGSPLLADVNWEAVLQKKVTPSFLP</Hsp_qseq>
      <Hsp_hseq>VILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQ-NQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPF---SGDDEDEVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFFRNINFDDILNLRVKPPYIP</Hsp_hseq>
      <Hsp_midline>V + + ++T  + A+K + K   I+  ++ +   E ++     + +H FL NL+ SFQ E  ++  ++ + GGDL +H+Q + R      + Y  E+ LAL Y     +I+RD+K +NILL               DE             PE     +     Y+ AVDWW+ GV  Y++L    P+   S    DE+   + T    Y    + E+  + + LL   P+ R  +  R    V   P   ++N++ +L  +V P ++P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>101.679</Hsp_bit-score>
      <Hsp_score>252</Hsp_score>
      <Hsp_evalue>1.84971e-24</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>711</Hsp_query-to>
      <Hsp_hit-from>510</Hsp_hit-from>
      <Hsp_hit-to>794</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>133</Hsp_positive>
      <Hsp_gaps>57</Hsp_gaps>
      <Hsp_align-len>289</Hsp_align-len>
      <Hsp_qseq>VCIVQKRDTRTMYAMKYMNKQVCIERDEVRNVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQ--QSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEHAPEMFRSY-------------VEG----------------------------APR------YSSAVDWWSLGVTAYELLRGWRPYEIHSSTTIDEILQILDTK-SVHYSSCWSQEMASLLRKLLCLKPKNRWA---SLARVQGSPLLADVNWEAVLQKKVTPSFLP</Hsp_qseq>
      <Hsp_hseq>VFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFK--GDNTNETFTNILKNEVSFPNNNEISRTCKDLIKKLLTKNESKRLGCKMGAADVKKHPFFKKVQWS--LLRNQEPPLIP</Hsp_hseq>
      <Hsp_midline>V +V+++ T  +YA+K ++K   I+R++++ V  E +I+    H F+V L++SFQ E+ +++ ++  +GG+    LQ  ++    E+  R Y  E++ AL+YL     I+RD+KP+NILL +    M   +             V+G                            AP       +++AVDWW+LG+  YE+L G+ P++     T +    IL  + S   ++  S+    L++KLL      R       A V+  P    V W   L +   P  +P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>98.9821</Hsp_bit-score>
      <Hsp_score>245</Hsp_score>
      <Hsp_evalue>3.99208e-24</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>615</Hsp_query-to>
      <Hsp_hit-from>118</Hsp_hit-from>
      <Hsp_hit-to>343</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>114</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>229</Hsp_align-len>
      <Hsp_qseq>VCIVQKRDTRTMYAMKYMNKQVCIERDEVRNVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDE--------------HAPEMFRSYVEG-----AP------RYSSAVDWWSLGVTAYELLRGWRPYEIHSSTTIDEILQILDTKSVHYSSCWSQEMASLLRKLLCLKPKNR</Hsp_qseq>
      <Hsp_hseq>VYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIK---MPSNISQDAQDLILKLLKYDPKDR</Hsp_hseq>
      <Hsp_midline>V  V+ R T  + A+K M K+  I+ +  +   RE++I   L H  L   +  F DE+ ++++++ L+ G++   L+    F +     Y+ +++ ALDY+ +++IIHRDIKP+NIL+                + PE  R  V G     +P       Y   +D W+LGV A+ELL G  P+E     T  + +  LD K     S  SQ+   L+ KLL   PK+R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>94.3597</Hsp_bit-score>
      <Hsp_score>233</Hsp_score>
      <Hsp_evalue>5.86515e-22</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>360</Hsp_query-to>
      <Hsp_hit-from>366</Hsp_hit-from>
      <Hsp_hit-to>484</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>119</Hsp_align-len>
      <Hsp_qseq>VCIVQKRDTRTMYAMKYMNKQVCIERDEVRNVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLD</Hsp_qseq>
      <Hsp_hseq>VRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILID</Hsp_hseq>
      <Hsp_midline>V +VQK+DT  +YAMK + K    ++D++ +V  E  ++   +  ++V+L+YSFQD + ++++++ L GGDL   L +   F E+  R Y+ E  LA++ + +   IHRDIKPDNIL+D</Hsp_midline>
    </Hsp>
    <Hsp>
      <Hsp_num>2</Hsp_num>
      <Hsp_bit-score>45.8246</Hsp_bit-score>
      <Hsp_score>107</Hsp_score>
      <Hsp_evalue>4.90497e-06</Hsp_evalue>
      <Hsp_query-from>367</Hsp_query-from>
      <Hsp_query-to>759</Hsp_query-to>
      <Hsp_hit-from>579</Hsp_hit-from>
      <Hsp_hit-to>708</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>58</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>143</Hsp_align-len>
      <Hsp_qseq>APEMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWRPY--EIHSST-----TIDEILQILDTKSVHYSSCWSQEMASLLRKLLCLKPK--NRWASLARVQGSPLLADVNWEAVLQKKVTPSFLPNKGQLNCD---PTFELEEM</Hsp_qseq>
      <Hsp_hseq>APEIF--LYQG---YGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISY------EAEDLIRRLLTHADQRLGRHGGADEIKSHPFFRGVDWNTIRQ--VEAPYIPKLSSITDTRFFPTDELENV</Hsp_hseq>
      <Hsp_midline>APE+F    +G   Y    DWWSLG   YE L GW P+  E    T       ++ LQ  D   + Y      E   L+R+LL    +   R      ++  P    V+W  + Q  V   ++P    +      PT ELE +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>92.4337</Hsp_bit-score>
      <Hsp_score>228</Hsp_score>
      <Hsp_evalue>1.61844e-21</Hsp_evalue>
      <Hsp_query-from>97</Hsp_query-from>
      <Hsp_query-to>618</Hsp_query-to>
      <Hsp_hit-from>199</Hsp_hit-from>
      <Hsp_hit-to>407</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>211</Hsp_align-len>
      <Hsp_qseq>VFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILL-----------------------DEHAPEMFRSY--VEGAPR-----------YSSAVDWWSLGVTAYELLRGWRPYE-IHSSTTIDEILQILDTKSVHYSSCWSQEMASLLRKLLCLKPKNRW</Hsp_qseq>
      <Hsp_hseq>TFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIPF--YLSEGMKDILNALLKKETAKRW</Hsp_hseq>
      <Hsp_midline> F E  I+ E+EH  +V L+YSF D   +++++  + GG+L YHL++     E  V  Y  E+S AL +L  + +++RD+KP+N LL                       DE  PE   +   + G P            YS   DW+SLG   Y++L G  PY   +    I++I Q      + +    S+ M  +L  LL  +   RW</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.5817</Hsp_bit-score>
      <Hsp_score>218</Hsp_score>
      <Hsp_evalue>4.51569e-20</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>672</Hsp_query-to>
      <Hsp_hit-from>139</Hsp_hit-from>
      <Hsp_hit-to>397</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>121</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>264</Hsp_align-len>
      <Hsp_qseq>VCIVQKRDTRTMYAMKYMNKQVCIERDEVRNVFRELQIMQELEHT-FLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEHA-------------PEMFRSYVEGAPRY--------------------------SSAVDWWSLGVTAYELLRGWRPYEIHSS-TTIDEILQILDTKSVHYSSCWSQEMASLLRKLLCLKPKNRWASLARVQGSPLLADVNWE</Hsp_qseq>
      <Hsp_hseq>VVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQKLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKI----QYAFTAGFPQIVKDLVKKLLVRDPNDRL-TIKQIKAHLFFHEVNFE</Hsp_hseq>
      <Hsp_midline>V +   RD+   YA+K ++K+  I + +V+ V  E   +Q+L  T  +  L+++FQDE  ++ +++    GD    +++     E   R Y  ++  A+D L    IIHRDIKP+NILLD++              PE   +  +G P +                           S  D W+ G   Y++L G  P++  +   T  ++++I       +++ + Q +  L++KLL   P +R  ++ +++      +VN+E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.1965</Hsp_bit-score>
      <Hsp_score>217</Hsp_score>
      <Hsp_evalue>7.05304e-20</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>615</Hsp_query-to>
      <Hsp_hit-from>218</Hsp_hit-from>
      <Hsp_hit-to>454</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>242</Hsp_align-len>
      <Hsp_qseq>RDTRTMYAMKYMNKQVCIERDEVRNVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEHAPEMFR------SYVEG---------------AP-------------------RYSSAVDWWSLGVTAYELLRGWRPYEIHSSTTIDEILQILDTKSVHYSSC----WSQEMASLLRKLLCLKPKNR</Hsp_qseq>
      <Hsp_hseq>RTTGKTFAVKIISKRKVI--GNMDGVTRELEVLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPF---SGSTQDQLYKQIGRGSYHEGPLKDFRISEEARDFIDSLLQVDPNNR</Hsp_hseq>
      <Hsp_midline>R T   +A+K ++K+  I    +  V REL+++Q+L H  +V L   ++D E  +MV++ + GGDL   +       E+A R    ++  A+ Y+    I HRD+KPDNIL+++  P + +      + V+G               AP                    YSS VD WS+G   Y +L G  P+   S +T D++ + +   S H         S+E    +  LL + P NR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.9593</Hsp_bit-score>
      <Hsp_score>206</Hsp_score>
      <Hsp_evalue>1.84411e-18</Hsp_evalue>
      <Hsp_query-from>7</Hsp_query-from>
      <Hsp_query-to>615</Hsp_query-to>
      <Hsp_hit-from>96</Hsp_hit-from>
      <Hsp_hit-to>325</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>231</Hsp_align-len>
      <Hsp_qseq>CIVQKRDTRTMYAMKYMNKQVCIERDEVRNVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEH--------------APEMFRSY-VEGAPRY-------------SSAVDWWSLGVTAYELLRGWRPYEIHSSTTIDEILQILDTKSVHYSSCWSQEMASLLRKLLCLKPKNR</Hsp_qseq>
      <Hsp_hseq>CFQIKDDSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDF-SFPRDKPISDEGKILIRDILSLDPIER</Hsp_hseq>
      <Hsp_midline>C   K D+  ++A K + K         + +  E+QI + + H  +V     F+D+ ++++++++   G L   L++     E  VR +  ++  A+ Y+  R +IHRD+K  NI  D +              A E  R Y + G P Y             S  VD WSLGV  Y LL G  P++     TI E ++  D  S       S E   L+R +L L P  R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.4925</Hsp_bit-score>
      <Hsp_score>197</Hsp_score>
      <Hsp_evalue>2.75887e-17</Hsp_evalue>
      <Hsp_query-from>13</Hsp_query-from>
      <Hsp_query-to>672</Hsp_query-to>
      <Hsp_hit-from>29</Hsp_hit-from>
      <Hsp_hit-to>299</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>118</Hsp_positive>
      <Hsp_gaps>53</Hsp_gaps>
      <Hsp_align-len>272</Hsp_align-len>
      <Hsp_qseq>VQKRDTRTMYAMKYMNKQVCIERDEVRNVFRE---LQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEHAPEMFRSYVEGA---PRYSS----------------------------------------AVDWWSLGVTAYELLRGWRPYEIHSSTTIDEILQILD------TKSVHYSSCWSQEMASLLRKLLCLKPKNRWASLARVQGSPLLADVNWE</Hsp_qseq>
      <Hsp_hseq>LDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPFRGENELKTFEKIVALDYPWGPNNRINNSTSPINPLVINLVQKILVIE-VNERISLEQIKRHPYFSKVDWN</Hsp_hseq>
      <Hsp_midline>+ K+    +YA+K  +K+  I+  +V+ V  E   + ++ +  H  ++ L+Y+F DEE+++ V+D   GG+L   L +   F +   R +  +L  AL+++    IIHRD+KP+N+LLD     M   +   A   P  S                                           D W+LG   Y+ ++G  P+   +     E +  LD       +  + +S  +  + +L++K+L ++  N   SL +++  P  + V+W </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.7962</Hsp_bit-score>
      <Hsp_score>190</Hsp_score>
      <Hsp_evalue>1.63581e-16</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>369</Hsp_query-to>
      <Hsp_hit-from>191</Hsp_hit-from>
      <Hsp_hit-to>312</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>122</Hsp_align-len>
      <Hsp_qseq>VCIVQKRDTRTMYAMKYMNKQVCIERDEVRNVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEHA</Hsp_qseq>
      <Hsp_hseq>VYLARKKDTKEVCALKILNKKLLFKLNETKHVLTERDILTTTRSEWLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINTRCLKSGHARFYISEMFCAVNALHDLGYTHRDLKPENFLIDAKG</Hsp_hseq>
      <Hsp_midline>V + +K+DT+ + A+K +NK++  + +E ++V  E  I+      +LV L Y+FQD + +++ ++ + GGD R  L  +   +    R Y+ E+  A++ L      HRD+KP+N L+D   </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.7962</Hsp_bit-score>
      <Hsp_score>190</Hsp_score>
      <Hsp_evalue>2.13868e-16</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>360</Hsp_query-to>
      <Hsp_hit-from>200</Hsp_hit-from>
      <Hsp_hit-to>312</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>113</Hsp_align-len>
      <Hsp_qseq>DTRTMYAMKYMNKQVCIERDEVRNVFRELQIMQELEHT-FLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLD</Hsp_qseq>
      <Hsp_hseq>DTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLD</Hsp_hseq>
      <Hsp_midline>DT+  YA K +NK+  I + +V+ V  E   +Q+L ++  +V L+ +FQDE  ++ +++    GD    +++     E   R Y  ++  A+DYL    IIHRDIKP+NILLD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YPR111W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:747306:749000:1 gene:YPR111W transcript:YPR111W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF20 description:Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006315]</Hit_def>
  <Hit_accession>YPR111W</Hit_accession>
  <Hit_len>564</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.0258</Hsp_bit-score>
      <Hsp_score>188</Hsp_score>
      <Hsp_evalue>3.01505e-16</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>360</Hsp_query-to>
      <Hsp_hit-from>183</Hsp_hit-from>
      <Hsp_hit-to>301</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>119</Hsp_align-len>
      <Hsp_qseq>VCIVQKRDTRTMYAMKYMNKQVCIERDEVRNVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLD</Hsp_qseq>
      <Hsp_hseq>VYLAKKKDSDEICALKILNKKLLFKLNETNHVLTERDILTTTRSDWLVKLLYAFQDPESLYLAMEFVPGGDFRTLLINTRILKSGHARFYISEMFCAVNALHELGYTHRDLKPENFLID</Hsp_hseq>
      <Hsp_midline>V + +K+D+  + A+K +NK++  + +E  +V  E  I+      +LV L Y+FQD E +++ ++ + GGD R  L  +   +    R Y+ E+  A++ L +    HRD+KP+N L+D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.6406</Hsp_bit-score>
      <Hsp_score>187</Hsp_score>
      <Hsp_evalue>4.95461e-16</Hsp_evalue>
      <Hsp_query-from>43</Hsp_query-from>
      <Hsp_query-to>615</Hsp_query-to>
      <Hsp_hit-from>82</Hsp_hit-from>
      <Hsp_hit-to>294</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>217</Hsp_align-len>
      <Hsp_qseq>AMKYMNKQVCIERDEVRNVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEH--------------APEMFRSYVEGAPRYSSA------------VDWWSLGVTAYELLRGWRPYEIHSSTTIDEILQILDTKSVHYSSCWSQEMASLLRKLLCLKPKNR</Hsp_qseq>
      <Hsp_hseq>ALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDES---IPVLFKNISNGVYTLPKFLSPGAAGLIKRMLIVNPLNR</Hsp_hseq>
      <Hsp_midline>A+K +NK+V  + D    + RE+  ++ L H  ++ L+   + ++++ MV++   G +L  ++ Q  +  E+  R +  ++  A++Y  +  I+HRD+KP+N+LLDEH                  F     G+P Y++             VD WS GV  Y +L    P++  S   I  + + +           S   A L++++L + P NR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YFL033C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:69115:74427:-1 gene:YFL033C transcript:YFL033C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM15 description:Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase [Source:SGD;Acc:S000001861]</Hit_def>
  <Hit_accession>YFL033C</Hit_accession>
  <Hit_len>1770</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>2.45376e-14</Hsp_evalue>
      <Hsp_query-from>4</Hsp_query-from>
      <Hsp_query-to>360</Hsp_query-to>
      <Hsp_hit-from>808</Hsp_hit-from>
      <Hsp_hit-to>927</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>120</Hsp_align-len>
      <Hsp_qseq>VCIVQKRDTRTMYAMKYMNKQVCIERDEVRNVFRELQIMQ-ELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLD</Hsp_qseq>
      <Hsp_hseq>VYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDKPYVARLFASFQNKDNLFLVMEYLPGGDLATLIKMMGYLPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLID</Hsp_hseq>
      <Hsp_midline>V + +K+ T   +A+K + K   I +++V NV  E  IM  + +  ++  L+ SFQ+++++F+V++ L GGDL   ++      ++  + YL E+ + ++ + Q  IIH D+KP+N+L+D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>6.18436e-14</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>483</Hsp_query-to>
      <Hsp_hit-from>234</Hsp_hit-from>
      <Hsp_hit-to>416</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>189</Hsp_align-len>
      <Hsp_qseq>RDTRTMYAMKYMNKQVCIERDEVRNVFRELQIMQELEHTFLVNLWYSFQDEED--MFMVVDLLLGGDL----RYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEH-----------------------------APEMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWRPYE</Hsp_qseq>
      <Hsp_hseq>KNGKKVFALKTIN-TMNTDPEYQKQIFRELQFNKSFKSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFGVSGEAVNSLAMTFTGTSFYMAPER----IQGQP-YSVTCDVWSLGLTLLEVAGGRFPFE</Hsp_hseq>
      <Hsp_midline>++ + ++A+K +N  +  + +  + +FRELQ  +  +  ++V  +  F DE+   +++ ++ + G  L    +  L++  R  E  +      +   L YL +R +IHRDIKP NILL+E                              APE     ++G P YS   D WSLG+T  E+  G  P+E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.3218</Hsp_bit-score>
      <Hsp_score>168</Hsp_score>
      <Hsp_evalue>9.66468e-14</Hsp_evalue>
      <Hsp_query-from>97</Hsp_query-from>
      <Hsp_query-to>693</Hsp_query-to>
      <Hsp_hit-from>93</Hsp_hit-from>
      <Hsp_hit-to>333</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>52</Hsp_gaps>
      <Hsp_align-len>246</Hsp_align-len>
      <Hsp_qseq>VFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNIL----------------------------------LDEHAPEMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWRPYEIHSSTTIDEILQILDTKSVHYSSCW---SQEMASLLRKLLCLKPKNR----------WASLARVQGSPLLADVNWEAVLQKKV</Hsp_qseq>
      <Hsp_hseq>LYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGHGKP-----CDIWSIGVITYTLLCGYSPFIAESVEGFMEECTASRYPVTFHMPYWDNISIDVKRFILKALRLNPADRPTATELLDDPWITSKRVETSNILPDVKKGFSLRKKL</Hsp_hseq>
      <Hsp_midline>++ EL I+Q+L H  +V+    F+ ++  ++V  L  GG+L   +    +F E      + ++  A++Y+  ++++HRD+KP+N+L                                  L   APE+      G P      D WS+GV  Y LL G+ P+   S     E           +   W   S ++   + K L L P +R          W +  RV+ S +L DV     L+KK+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.3218</Hsp_bit-score>
      <Hsp_score>168</Hsp_score>
      <Hsp_evalue>1.3063e-13</Hsp_evalue>
      <Hsp_query-from>28</Hsp_query-from>
      <Hsp_query-to>480</Hsp_query-to>
      <Hsp_hit-from>45</Hsp_hit-from>
      <Hsp_hit-to>220</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>179</Hsp_align-len>
      <Hsp_qseq>TRTMYAMKYMNKQVCIERDEVRNVFRELQIMQELEHTFLVNLWY-SFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEHA---------------PEMFRSYVEGAP------------RYSSAVDWWSLGVTAYELLRGWRPY</Hsp_qseq>
      <Hsp_hseq>TGRVYAIKVLNLDS--DSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLR-SLLRPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPY</Hsp_hseq>
      <Hsp_midline>T  +YA+K +N     + DEV +V RE+Q +  L+    +  +Y S+  +  ++++++   GG LR  L +  +  E+ + + + EL +AL  + + ++IHRDIK  N+L+                     + R  + G P             Y + VD WSLG+T YE+  G  PY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>1.3572e-13</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>477</Hsp_query-to>
      <Hsp_hit-from>38</Hsp_hit-from>
      <Hsp_hit-to>216</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>184</Hsp_align-len>
      <Hsp_qseq>RDTRTMYAMKYMNKQVCIERDEVRNVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQS--TRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEH------------------------------APEMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWRP</Hsp_qseq>
      <Hsp_hseq>RVTQEIVAIKVVNLEHSDEDIEL--LAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRDTFVGTPYWMAPEVVCCEVDG---YNEKADIWSLGITTYELLKGLPP</Hsp_hseq>
      <Hsp_midline>R T+ + A+K +N +   E  E+  + +E+  + EL+   + N   +  ++  M++V++   GG     L++S      EE V   + E++L L YL ++  IHRDIK  NILL+E                               APE+    V+G   Y+   D WSLG+T YELL+G  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.5514</Hsp_bit-score>
      <Hsp_score>166</Hsp_score>
      <Hsp_evalue>2.28176e-13</Hsp_evalue>
      <Hsp_query-from>61</Hsp_query-from>
      <Hsp_query-to>615</Hsp_query-to>
      <Hsp_hit-from>75</Hsp_hit-from>
      <Hsp_hit-to>301</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>228</Hsp_align-len>
      <Hsp_qseq>KQVCIE---RDEVRN-------VFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEHA----------------PEMFRSYVEGAPRYSSA-------------VDWWSLGVTAYELLRGWRPY-EIHSSTTIDEILQI---LDTKSVHYSSCWSQEMASLLRKLLCLKPKNR</Hsp_qseq>
      <Hsp_hseq>KQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMKTSC-GSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARLYKYITQTPLKFPEYITPIPRDLLRRILVPNPRRR</Hsp_hseq>
      <Hsp_midline>KQV I+   RD ++        ++RE+  ++ L H  ++ L    Q+ + + +V++ + GG+   ++Q+  R +E +      +L   ++Y+  + ++HRD+K +N+LLD+H                  E+ ++   G+P Y++               D WS GV  Y +L G+ P+ + H + T D+I ++   +    + +    +     LLR++L   P+ R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.5514</Hsp_bit-score>
      <Hsp_score>166</Hsp_score>
      <Hsp_evalue>2.31124e-13</Hsp_evalue>
      <Hsp_query-from>19</Hsp_query-from>
      <Hsp_query-to>717</Hsp_query-to>
      <Hsp_hit-from>148</Hsp_hit-from>
      <Hsp_hit-to>392</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>263</Hsp_align-len>
      <Hsp_qseq>KRDTRTMYAMKYMNKQVCIERDEVRNVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEH------------------------------APEMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWRPYEIHSSTTIDEILQILDTKSVHYSSCWSQEMASLLRKLLCLKPKNRWASLARVQGSPLLADVNWEAVLQKKVTPSFLPNK</Hsp_qseq>
      <Hsp_hseq>KNESEILERQKRLEKE--IARD--KRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELLKA----QPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIK---KGKVDYPSHLSIEVISLLTRMIVVDPLRR-ATLKNVVEHP------WMNRGYDFKAPSYVPNR</Hsp_hseq>
      <Hsp_midline>K ++  +   K + K+  I RD  +   RE  + Q L H  +  L+         +M+ + + GG L  ++ Q    +E   R +   ++ AL YL   +I+HRD+K +NI++                                 APE+ ++     P     VD WS G+  Y L+ G  P++  +S+ + E ++      V Y S  S E+ SLL +++ + P  R A+L  V   P      W         PS++PN+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>3.56423e-13</Hsp_evalue>
      <Hsp_query-from>103</Hsp_query-from>
      <Hsp_query-to>615</Hsp_query-to>
      <Hsp_hit-from>163</Hsp_hit-from>
      <Hsp_hit-to>357</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>198</Hsp_align-len>
      <Hsp_qseq>RELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDE---------------HAPEMFRSYVEGAPRYSS------------AVDWWSLGVTAYELLRGWRPYEIHSSTTIDEILQILDTKSVHYSSCWSQEMASLLRKLLCLKPKNR</Hsp_qseq>
      <Hsp_hseq>REIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPF---NDDNIKKLLLKVQSGKYQMPSNLSSEARDLISKILVIDPEKR</Hsp_hseq>
      <Hsp_midline>RE+ IM+ + HT ++ L+  ++++ ++++V++ + GG+L  +L    +  E     Y  ++   + Y    +I HRD+KP+N+LLD+                 P        G+P Y+S              D WS G+  + LL G  P+   +   I ++L  + +      S  S E   L+ K+L + P+ R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.781</Hsp_bit-score>
      <Hsp_score>164</Hsp_score>
      <Hsp_evalue>4.38734e-13</Hsp_evalue>
      <Hsp_query-from>73</Hsp_query-from>
      <Hsp_query-to>735</Hsp_query-to>
      <Hsp_hit-from>185</Hsp_hit-from>
      <Hsp_hit-to>419</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>46</Hsp_gaps>
      <Hsp_align-len>251</Hsp_align-len>
      <Hsp_qseq>IERDEVRNVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEH------------------------------APEMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWRPYEIHSSTTIDEILQILDTKSVHYSSCWSQEMASLLRKLLCLKPKNRWASLARVQGSPLLADVNWEAVLQKKVTPSFLPNKGQLNCD</Hsp_qseq>
      <Hsp_hseq>ISRD--KRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIYDSRKQLHTFCGSLYFAAPELLKA----NPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKIK---QGKVEYPQHLSIEVISLLSKMLVVDPK-RRATLKQV------VEHHWMVRGFNGPPPSYLPKRVPLTIE</Hsp_hseq>
      <Hsp_midline>I RD  +   RE  + Q L H  +  L+         +M+ + + GG L  ++ Q    +E   R +   ++ AL YL   +I+HRD+K +NI++ +                               APE+ ++     P     VD WS GV  + L+ G  P++  +S+ + E ++      V Y    S E+ SLL K+L + PK R A+L +V       + +W         PS+LP +  L  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>7.69276e-13</Hsp_evalue>
      <Hsp_query-from>1</Hsp_query-from>
      <Hsp_query-to>618</Hsp_query-to>
      <Hsp_hit-from>213</Hsp_hit-from>
      <Hsp_hit-to>469</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>55</Hsp_gaps>
      <Hsp_align-len>259</Hsp_align-len>
      <Hsp_qseq>MVCIVQKRDTRTMYAMKYMNKQVCIERDEVRNVFRELQIMQELEHTFLVNLWYSF-----QDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLD--------------------------------EHAPEM-FRSYVEGAPR-----------YSSAVDWWSLGVTAYELLRGWRPYEIH-SSTTIDEILQILDTKSVHYSSCWSQ---EMASLLRKLLCLKPKNRW</Hsp_qseq>
      <Hsp_hseq>LVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVILYVCLCGFPPFSDQLGPPSLKE--QILQAKYAFYSPYWDKIDDSVLHLISNLLVLNPDERY</Hsp_hseq>
      <Hsp_midline>+V   + + T    A+K  + Q   ++ + +    E  I+  ++H  +VNL  SF     + +   ++V++ +  G+L   + + T  +++  +    +L   L YL +++IIHRDIKP+NILL+                                +   EM F + + G P            Y+S VD WS GV  Y  L G+ P+       ++ E  QIL  K   YS  W +    +  L+  LL L P  R+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.2402</Hsp_bit-score>
      <Hsp_score>160</Hsp_score>
      <Hsp_evalue>1.50441e-12</Hsp_evalue>
      <Hsp_query-from>61</Hsp_query-from>
      <Hsp_query-to>615</Hsp_query-to>
      <Hsp_hit-from>75</Hsp_hit-from>
      <Hsp_hit-to>301</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>231</Hsp_align-len>
      <Hsp_qseq>KQVCIE---RDEVRN-------VFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQE-EAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEH-------------------------------APEMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWRPYEIHSS----TTIDEILQILDTKSVHYSSCWSQEMASLLRKLLCLKPKNR</Hsp_qseq>
      <Hsp_hseq>KQVAIKLIKRDSISNDYRKEVKIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLF-SQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVNEFCSRNELMKTSCGSPCYAAPELV---ISAEPYEARKADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGRLYNYINSTPLKFPDYILPIPRDLLRRMLVSDPKKR</Hsp_hseq>
      <Hsp_midline>KQV I+   RD + N       ++RE+  ++ L H  +V L    Q+   + +V++   GG+   ++Q+  R +E  A RL+  +L   + Y+  + ++HRD+K +N+LLD++                               APE+    +   P  +   D WS GV  Y +L G+ P++   +    + I  +   +++  + +          LLR++L   PK R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>1.56011e-12</Hsp_evalue>
      <Hsp_query-from>22</Hsp_query-from>
      <Hsp_query-to>477</Hsp_query-to>
      <Hsp_hit-from>241</Hsp_hit-from>
      <Hsp_hit-to>421</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>187</Hsp_align-len>
      <Hsp_qseq>RDTRTMYAMKYMNKQVCIERDEVRNVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDL-LLGG---DLRYH--LQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEH-----------------------------APEMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWRP</Hsp_qseq>
      <Hsp_hseq>KNGSKIFALKVIN-TLNTDPEYQKQIFRELQFNRSFQSEYIVRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVSGEAVNSLATTFTGTSFYMAPER----IQGQP-YSVTSDVWSLGLTILEVANGKFP</Hsp_hseq>
      <Hsp_midline>++   ++A+K +N  +  + +  + +FRELQ  +  +  ++V  +  F D+E+  + + +  +GG   D  Y   L++  R  E+ +      +   L YL ++ +IHRDIKP NILL+E+                             APE     ++G P YS   D WSLG+T  E+  G  P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>1.97944e-12</Hsp_evalue>
      <Hsp_query-from>97</Hsp_query-from>
      <Hsp_query-to>600</Hsp_query-to>
      <Hsp_hit-from>607</Hsp_hit-from>
      <Hsp_hit-to>808</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>85</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>202</Hsp_align-len>
      <Hsp_qseq>VFRELQIMQELEHTFLVNLWYSF-QDEEDMFMVVDLLLGGDLRYHLQQS-------TRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEHA---------------PEMFRSYVEGAP-----------RYSSAVDWWSLGVTAYELLRGWRPYEIHSSTTIDEILQILDTKSVHYSSCWSQEMASLLRKLLCL</Hsp_qseq>
      <Hsp_hseq>IVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATNGTPKLKHPESLSLEIKRFLSVCLCV</Hsp_hseq>
      <Hsp_midline>+  E+ +M++  H  +VN   ++ + ++D+++V++ + GG L   ++ S       +   E  +   + E    L +L  +HIIHRDIK DN+LLD  A                   R+ + G P            Y   +D WSLG+   E+L G  PY          ++    T  + +    S E+   L   LC+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>8.38553e-12</Hsp_evalue>
      <Hsp_query-from>97</Hsp_query-from>
      <Hsp_query-to>480</Hsp_query-to>
      <Hsp_hit-from>83</Hsp_hit-from>
      <Hsp_hit-to>239</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>163</Hsp_align-len>
      <Hsp_qseq>VFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEE-AVRLYLCELSLALDYLQQRHIIHRDIKPDNILL----------------------DEH------------APEMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWRPY</Hsp_qseq>
      <Hsp_hseq>LYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRI-LVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHGKP-----CDIWSIGVITYTLLCGYSAF</Hsp_hseq>
      <Hsp_midline>++ EL I+Q L H  +V     F+ ++  +++  L  GG+L   + +  +F EE AVR+ L E+  A+ Y+  ++I+HRD+KP+N+L                       DE             APE+      G P      D WS+GV  Y LL G+  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>1.12772e-11</Hsp_evalue>
      <Hsp_query-from>58</Hsp_query-from>
      <Hsp_query-to>663</Hsp_query-to>
      <Hsp_hit-from>62</Hsp_hit-from>
      <Hsp_hit-to>302</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>113</Hsp_positive>
      <Hsp_gaps>61</Hsp_gaps>
      <Hsp_align-len>252</Hsp_align-len>
      <Hsp_qseq>NKQVCIER--DEVRNVFRELQIMQELEHTFLVNLWYSF-----QDEEDMFMVVDLL---LGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQ-RHIIHRDIKPDNILLDE-------------------------------HAPEMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWRPYEIHSST-TIDEILQILDTKSVHYSSCWSQEMASLLRKLLCLK-PKNRWASLARV------QGSPLLADV</Hsp_qseq>
      <Hsp_hseq>NEKVAIKKVLQDKRFKNRELEIMKMLSHINIIDLKYFFYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVSYICSRYYRAPEL----IFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILGTPS-------KQEICSMNPNYMEHKFPQIKPIPLSRVFKKEDDQTVEFLADV</Hsp_hseq>
      <Hsp_midline>N++V I++   + R   REL+IM+ L H  +++L Y F     QDE  + ++++ +   L   LR+ + Q T      ++ Y+ +L  +L+YL    ++ HRDIKP N+L+D                                 APE+    + GA  Y++ +D WS G    ELL G   +   S    + EI++IL T S        QE+ S+    +  K P+ +   L+RV      Q    LADV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>1.46804e-10</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>615</Hsp_query-to>
      <Hsp_hit-from>37</Hsp_hit-from>
      <Hsp_hit-to>269</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>237</Hsp_align-len>
      <Hsp_qseq>DTRTMYAMKYMNKQVCIERD-EVRNVFRELQIMQEL-EHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQ-QRHIIHRDIKPDNILLDEH----------------------------------APEMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWRPYEIHSSTTIDEILQILDTKSVHYSSCWSQ---EMASLLRKLLCLKPKNR</Hsp_qseq>
      <Hsp_hseq>DPSIILAVKFIHVPTCKKMGLSDKDITKEVVLQSKCSKHPNVLRLIDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSE-EG--YYADRTDIWSIGILLFVLLTGQTPWELPSLENEDFVFFIENDGNLNWGP-WSKIEFTHLNLLRKILQPDPNKR</Hsp_hseq>
      <Hsp_midline>D   + A+K+++   C +     +++ +E+ +  +  +H  ++ L      +E M++++++  GGDL   ++       +  + Y  +L  A++YL  +  + HRDIKP+NILLD++                                  APE+  S  EG   Y+   D WS+G+  + LL G  P+E+ S    D +  I +  ++++   WS+      +LLRK+L   P  R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>1.65251e-10</Hsp_evalue>
      <Hsp_query-from>103</Hsp_query-from>
      <Hsp_query-to>615</Hsp_query-to>
      <Hsp_hit-from>80</Hsp_hit-from>
      <Hsp_hit-to>277</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>203</Hsp_align-len>
      <Hsp_qseq>RELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQE-EAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEH------------------------------APEMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWRPYEIHSSTTIDEILQILDTK-SVHYSSCWSQEMASLLRKLLCLKPKNR</Hsp_qseq>
      <Hsp_hseq>REIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFR-QIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALETEGKLLETSCGSPHYAAPEI----VSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERR</Hsp_hseq>
      <Hsp_midline>RE+ IM+ L H  ++ L+  ++   D+++V++    G+L   L +     E EA+R +  ++ + + Y     I+HRD+KP+N+LLD                                APE+    V G P    A D WS GV  + LL G  P++         +L++   +  +      S+E   L+RK+L + P+ R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>3.61269e-10</Hsp_evalue>
      <Hsp_query-from>73</Hsp_query-from>
      <Hsp_query-to>639</Hsp_query-to>
      <Hsp_hit-from>493</Hsp_hit-from>
      <Hsp_hit-to>708</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>218</Hsp_align-len>
      <Hsp_qseq>IERDEVRNVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLD--------------EHAP----EMFRSYVEGA-----------PRYSSAVDWWSLGVTAYELLRGWRPYEIHSSTTIDEILQILDTKSVHYSSCWSQEMASLLRKLLCLKPKNRWASLARVQ</Hsp_qseq>
      <Hsp_hseq>IHRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQ--MQAIFKIGTNTTPEIPSWATSEGKNFLRKAFELDYQYRPSALELLQ</Hsp_hseq>
      <Hsp_midline>I R  V  +  E+ +++EL H  +V  + + Q+  ++ + ++ + GG +   L     F+E  +  +  ++ + + YL +++IIHRDIK  NIL+D              + +P    +  R+ ++G+              ++  D WS G    E+  G  P+   S   +  I +I    +    S  + E  + LRK   L  + R ++L  +Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.5362</Hsp_bit-score>
      <Hsp_score>140</Hsp_score>
      <Hsp_evalue>4.17527e-10</Hsp_evalue>
      <Hsp_query-from>103</Hsp_query-from>
      <Hsp_query-to>480</Hsp_query-to>
      <Hsp_hit-from>210</Hsp_hit-from>
      <Hsp_hit-to>385</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>78</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>176</Hsp_align-len>
      <Hsp_qseq>RELQIMQELEHTFLVNLWYSFQDEED-MFMVVDLLLGGDLRYHLQQS---TRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILL----------------------------------DEHAPEM--------FRSYVEGAP----RYSSAVDWWSLGVTAYELLRGWRPY</Hsp_qseq>
      <Hsp_hseq>KEARILLRLDHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGISPF</Hsp_hseq>
      <Hsp_midline>+E +I+  L+H  ++ ++++F D  + +++  DL+ GGDL  +L +    T   E    L + ++  AL+YL  + I+HRD+K DNILL                                  +  APE+        ++S+   A      Y S  D WSLGV  + +L G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>6.08325e-10</Hsp_evalue>
      <Hsp_query-from>106</Hsp_query-from>
      <Hsp_query-to>480</Hsp_query-to>
      <Hsp_hit-from>1228</Hsp_hit-from>
      <Hsp_hit-to>1380</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>158</Hsp_align-len>
      <Hsp_qseq>ELQIMQELEHTFLVNLWYSFQDEEDMF-MVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEH--------------------------------APEMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWRPY</Hsp_qseq>
      <Hsp_hseq>EVSTLKDLDHLNIVQ-YLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEM----VDTKQGYSAKVDIWSLGCIVLEMFAGKRPW</Hsp_hseq>
      <Hsp_midline>E+  +++L+H  +V  +  F+++ +++ + ++ + GG +   ++   RF E  ++    ++   L YL  + I+HRD+K DN+LLD+                                 APEM    V+    YS+ VD WSLG    E+  G RP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>6.37502e-10</Hsp_evalue>
      <Hsp_query-from>94</Hsp_query-from>
      <Hsp_query-to>615</Hsp_query-to>
      <Hsp_hit-from>73</Hsp_hit-from>
      <Hsp_hit-to>273</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>206</Hsp_align-len>
      <Hsp_qseq>NVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQE-EAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEH------------------------------APEMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWRPYEIHSSTTIDEILQILDTK-SVHYSSCWSQEMASLLRKLLCLKPKNR</Hsp_qseq>
      <Hsp_hseq>NIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFR-QIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEI----VSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQR</Hsp_hseq>
      <Hsp_midline>N+ RE+ IM+ L H  +++L+  ++   +++++++    G+L   L       E EA+  +  ++ + + Y     I+HRD+KP+N+LLD                                APE+    V G P    A D WS GV  + LL G  P++  +    D +L++   +  +   +  S++   L+ K+L + P+ R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>6.52173e-10</Hsp_evalue>
      <Hsp_query-from>28</Hsp_query-from>
      <Hsp_query-to>615</Hsp_query-to>
      <Hsp_hit-from>642</Hsp_hit-from>
      <Hsp_hit-to>859</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>55</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>225</Hsp_align-len>
      <Hsp_qseq>TRTMYAMKYMNKQVCIERDEVRNVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQS--TRFQEEAVRLYLCELSLA-LDYLQQRHIIHRDIKPDNILLDEHAP---------------EMFRSYVEGAP-----------RYSSAVDWWSLGVTAYELLRGWRPYEIHSSTTIDEILQILDTKSVHYSSCWSQEMASLLRKLLCLKPKNR</Hsp_qseq>
      <Hsp_hseq>TNVSVAIKQMNLEKQPKKELIIN---EILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVTHCILTEGQIGAV----CRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPPYLNETPLRALYLIATNGTPKLKEPENLSSSLKKFLDWCLCVEPEDR</Hsp_hseq>
      <Hsp_midline>T    A+K MN +   +++ + N   E+ +M+  +H  +VN   S+  + D++++++ + GG L   +     T  Q  AV    C  +L+ L++L  + ++HRDIK DNILL                     + R+ + G P            Y   VD WSLG+   E++ G  PY   +      ++    T  +      S  +   L   LC++P++R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>2.04175e-09</Hsp_evalue>
      <Hsp_query-from>61</Hsp_query-from>
      <Hsp_query-to>588</Hsp_query-to>
      <Hsp_hit-from>54</Hsp_hit-from>
      <Hsp_hit-to>251</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>206</Hsp_align-len>
      <Hsp_qseq>KQVCIERDE-VRNVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQS-TRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEH----------------------------APEMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWRPYEIHSSTTIDEILQILDTKSVHYSSCWSQEMASLLRK</Hsp_qseq>
      <Hsp_hseq>KEVVYENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSALTLAGTLNWMAPEIL-----GNRGASTLSDIWSLGATVVEMLTKNPPY--HNLTDAN-IYYAVENDTYYPPSSFSEPLKDFLSK</Hsp_hseq>
      <Hsp_midline>K+V  E DE + ++  E+ +++ L H  +V      +   +++++++    G LR  + +S T   E   + Y+ +  L L YL    +IHRDIK  NILL                               APE+      G    S+  D WSLG T  E+L    PY  H+ T  + I   ++  + +  S +S+ +   L K</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>3.68537e-09</Hsp_evalue>
      <Hsp_query-from>88</Hsp_query-from>
      <Hsp_query-to>468</Hsp_query-to>
      <Hsp_hit-from>64</Hsp_hit-from>
      <Hsp_hit-to>213</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>74</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>153</Hsp_align-len>
      <Hsp_qseq>VRNVFRELQIMQELEHTFLVNLWYSFQDE-EDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEHA--------------PEMFRSYVEG----AP-------RYSSAVDWWSLGVTAYELLRG</Hsp_qseq>
      <Hsp_hseq>AKRTYRELKLLKHLRHENLICLQDIFLSPLEDIYFVTELQ-GTDL-HRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQM-TGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEG</Hsp_hseq>
      <Hsp_midline> +  +REL++++ L H  L+ L   F    ED++ V +L  G DL + L Q+   +++ V+ +L ++   L Y+    +IHRD+KP NIL++E+               P+M   YV      AP       +Y   VD WS G    E++ G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>4.79905e-09</Hsp_evalue>
      <Hsp_query-from>61</Hsp_query-from>
      <Hsp_query-to>480</Hsp_query-to>
      <Hsp_hit-from>389</Hsp_hit-from>
      <Hsp_hit-to>564</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>44</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>176</Hsp_align-len>
      <Hsp_qseq>KQVCIERDEV--RNVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQ--EEAVRLYLCELSL-ALDYLQQRH-IIHRDIKPDNILLDEH------------------------------APEMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWRPY</Hsp_qseq>
      <Hsp_hseq>KEVRLELDEAKFRQILMELEVLHKCNSPYIVDFYGAFFIEGAVYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSANQGTVKLCDFGVSGNLVASLAKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPY</Hsp_hseq>
      <Hsp_midline>K+V +E DE   R +  EL+++ +    ++V+ + +F  E  ++M ++ + GG L     +S+     +E    ++    +  L  L+++H IIHRD+KP NIL   +                              APE  +S       Y+   D WSLG++  E+  G  PY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YDL079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:312951:314748:-1 gene:YDL079C transcript:YDL079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRK1 description:Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication [Source:SGD;Acc:S000002237]</Hit_def>
  <Hit_accession>YDL079C</Hit_accession>
  <Hit_len>501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.0694</Hsp_bit-score>
      <Hsp_score>131</Hsp_score>
      <Hsp_evalue>5.59819e-09</Hsp_evalue>
      <Hsp_query-from>58</Hsp_query-from>
      <Hsp_query-to>525</Hsp_query-to>
      <Hsp_hit-from>187</Hsp_hit-from>
      <Hsp_hit-to>378</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>199</Hsp_align-len>
      <Hsp_qseq>NKQVCIER--DEVRNVFRELQIMQELEHTFLVNLWYSF--QDEED---MFMVVDLL---LGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQ-RHIIHRDIKPDNILLDE-------------------------------HAPE-MFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWRPYEIHSSTTIDEILQIL</Hsp_qseq>
      <Hsp_hseq>NQKVAIKKVLQDRRYKNRELETMKMLCHPNTVGLQYYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYICSRYYRAPELMF-----GATNYSNQVDVWSSACVIAELLLG-KPL-FSGESGIDQLVEII</Hsp_hseq>
      <Hsp_midline>N++V I++   + R   REL+ M+ L H   V L Y F  +DEED   + +V+D +   L   LR+ +    +     ++ Y  +L  AL+YL     I HRDIKP N+L+D                                 APE MF     GA  YS+ VD WS      ELL G +P      + ID++++I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>1.84716e-08</Hsp_evalue>
      <Hsp_query-from>97</Hsp_query-from>
      <Hsp_query-to>480</Hsp_query-to>
      <Hsp_hit-from>419</Hsp_hit-from>
      <Hsp_hit-to>582</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>42</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>164</Hsp_align-len>
      <Hsp_qseq>VFRELQIMQELEHTFLVNLWYSFQ-DEEDMFMVVDLLLGGDLRYHL---------QQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEHA---------------PEMFRSYVEGAP-----------RYSSAVDWWSLGVTAYELLRGWRPY</Hsp_qseq>
      <Hsp_hseq>IMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPPY</Hsp_hseq>
      <Hsp_midline>+  EL +M +     +VN   ++  D+E+++++++ + GG L   L         + S+   E  +   + E    L +L  + IIHRDIK DNILL+                      R+ + G P            Y   VD WSLG+   E++ G  PY</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>4.60351e-08</Hsp_evalue>
      <Hsp_query-from>61</Hsp_query-from>
      <Hsp_query-to>654</Hsp_query-to>
      <Hsp_hit-from>65</Hsp_hit-from>
      <Hsp_hit-to>287</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>229</Hsp_align-len>
      <Hsp_qseq>KQVCIERDEVR--NVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEHAPE-----------MFRSYVE---GAPRYSSA------------VDWWSLGVTAYELLRGWRPYEIHSSTTIDEIL---QILDTKSVHYSSCWSQEMASLLRKLLCLKPKNRWASLARVQGSPLL</Hsp_qseq>
      <Hsp_hseq>RKVCLKTSDKNDPNIVREVFYHRQFDFPYITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTRECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDD-----DEAKTKWKIVNEEPKYDAKVIPDDARDLISRLLAKNPGER-PSLSQVLRHPFL</Hsp_hseq>
      <Hsp_midline>++VC++  +    N+ RE+   ++ +  ++  L+     E  ++M ++   G +L  HL    R           ++S A+ Y    H +HRD+K +NILLD++              M ++ +E   G   Y +             +D WSLGV  Y L+ G+ P++       DE     +I++ +  + +     +   L+ +LL   P  R  SL++V   P L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>7.45713e-08</Hsp_evalue>
      <Hsp_query-from>154</Hsp_query-from>
      <Hsp_query-to>513</Hsp_query-to>
      <Hsp_hit-from>199</Hsp_hit-from>
      <Hsp_hit-to>368</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>72</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>170</Hsp_align-len>
      <Hsp_qseq>WYSFQDEEDMF-MVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILL---------------DEHAP---------------------------------EMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWRP-YEIHSSTTIDEI</Hsp_qseq>
      <Hsp_hseq>FIAFQESANYYYLVTELVTGGEIFDRIVQLTCFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLRNNTAKTPCGTIEYVASEVFTSKRYSMKVDMWSIGCVLFTLLCGYPPFYEKNEKTLLKKI</Hsp_hseq>
      <Hsp_midline>+ +FQ+  + + +V +L+ GG++   + Q T F E+  R  + ++++A+ ++    I+HRD+KP+N+L                DE                                    E   S V  + RYS  VD WS+G   + LL G+ P YE +  T + +I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>9.20654e-07</Hsp_evalue>
      <Hsp_query-from>61</Hsp_query-from>
      <Hsp_query-to>558</Hsp_query-to>
      <Hsp_hit-from>36</Hsp_hit-from>
      <Hsp_hit-to>233</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>202</Hsp_align-len>
      <Hsp_qseq>KQVCIERDE--VRNVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQST------RFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEHAP----------------EMFRSYV-----------EGAPRYSSAVDWWSLGVTAYELLRGWRPYEIHSSTTIDEILQ-ILDTKSVHYSSCW</Hsp_qseq>
      <Hsp_hseq>KEVKLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFM-DNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITG-KP--LFPGTNDEEQLKLIFDIMGTPNESLW</Hsp_hseq>
      <Hsp_midline>K+V ++ +E       RE+ +M+EL+H  +V L+     E  + +V + +   DL+ ++   T        +   V+ +  +L   L +  +  I+HRD+KP N+L+++                     F S V            G+  YS+++D WS G    E++ G +P  +   T  +E L+ I D       S W</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.3654</Hsp_bit-score>
      <Hsp_score>111</Hsp_score>
      <Hsp_evalue>1.86341e-06</Hsp_evalue>
      <Hsp_query-from>106</Hsp_query-from>
      <Hsp_query-to>360</Hsp_query-to>
      <Hsp_hit-from>1083</Hsp_hit-from>
      <Hsp_hit-to>1167</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>6</Hsp_gaps>
      <Hsp_align-len>88</Hsp_align-len>
      <Hsp_qseq>ELQIMQELEHTFLVNLWYSFQ---DEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLD</Hsp_qseq>
      <Hsp_hseq>EMTVLEMLNHPNIVQ-YYGVEVHRDKVNIFM--EYCEGGSLASLLDHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLD</Hsp_hseq>
      <Hsp_midline>E+ +++ L H  +V  +Y  +   D+ ++FM  +   GG L   L       E   ++Y  EL   L YL Q  ++HRDIKP+NILLD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YLR248W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:634252:636084:1 gene:YLR248W transcript:YLR248W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK2 description:Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004238]</Hit_def>
  <Hit_accession>YLR248W</Hit_accession>
  <Hit_len>610</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.595</Hsp_bit-score>
      <Hsp_score>109</Hsp_score>
      <Hsp_evalue>2.8085e-06</Hsp_evalue>
      <Hsp_query-from>154</Hsp_query-from>
      <Hsp_query-to>360</Hsp_query-to>
      <Hsp_hit-from>253</Hsp_hit-from>
      <Hsp_hit-to>322</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>21</Hsp_identity>
      <Hsp_positive>44</Hsp_positive>
      <Hsp_gaps>1</Hsp_gaps>
      <Hsp_align-len>70</Hsp_align-len>
      <Hsp_qseq>WYSFQDEEDMFMVV-DLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLD</Hsp_qseq>
      <Hsp_hseq>FIDFQETDSYYYIIQELLTGGEIFGEIVRLTYFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFE</Hsp_hseq>
      <Hsp_midline>+  FQ+ +  + ++ +LL GG++   + + T F E+  R  + +L+LA+ ++    ++HRDIKP+N+L +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.595</Hsp_bit-score>
      <Hsp_score>109</Hsp_score>
      <Hsp_evalue>3.54489e-06</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>480</Hsp_query-to>
      <Hsp_hit-from>46</Hsp_hit-from>
      <Hsp_hit-to>267</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>70</Hsp_gaps>
      <Hsp_align-len>222</Hsp_align-len>
      <Hsp_qseq>DTRTMYAMKYMNKQVCIERDEVRNVFRELQIMQELEHTFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRL------------------------YLCELSLALDYLQQRHIIHRDIKPDNILLDE-----HAPEMFR---------------------------SYVE---GAP-----------RYSSAVDWWSLGVTAYELLRGWRPY</Hsp_qseq>
      <Hsp_hseq>DKSQHVAIKEVSRAKLKNKKLLENLEIEIAILKKIKHPHIVGLIDCERTSTDFYLIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVVFEMCCGTPPF</Hsp_hseq>
      <Hsp_midline>D     A+K +++     +  + N+  E+ I+++++H  +V L    +   D +++++    GDL + L++     E    L                        YL +L+ AL +L+ ++++HRDIKP N+LL       H  + F                            S  E   G+P           +Y++  D WS+G   +E+  G  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>46.595</Hsp_bit-score>
      <Hsp_score>109</Hsp_score>
      <Hsp_evalue>3.62279e-06</Hsp_evalue>
      <Hsp_query-from>25</Hsp_query-from>
      <Hsp_query-to>360</Hsp_query-to>
      <Hsp_hit-from>1287</Hsp_hit-from>
      <Hsp_hit-to>1399</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>61</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>116</Hsp_align-len>
      <Hsp_qseq>DTRTMYAMKYMNKQVCIERDEVRNVFRE-LQIMQELEHTFLVNLWYSFQ---DEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLD</Hsp_qseq>
      <Hsp_hseq>DNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNHPNIVS-YYGVEVHRDKVNIFM--EYCEGGSLAALLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLD</Hsp_hseq>
      <Hsp_midline>D   + A+K +N Q      ++  + +E + +++ L H  +V+ +Y  +   D+ ++FM  +   GG L   L+      E   ++Y  +L   L YL +  I+HRD+KP+NILLD</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.4394</Hsp_bit-score>
      <Hsp_score>106</Hsp_score>
      <Hsp_evalue>6.88369e-06</Hsp_evalue>
      <Hsp_query-from>106</Hsp_query-from>
      <Hsp_query-to>597</Hsp_query-to>
      <Hsp_hit-from>894</Hsp_hit-from>
      <Hsp_hit-to>1081</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>86</Hsp_positive>
      <Hsp_gaps>52</Hsp_gaps>
      <Hsp_align-len>202</Hsp_align-len>
      <Hsp_qseq>ELQIMQELEHTFLVNLW--YSFQDEEDMFMVVDLLLGGDLRYHLQQSTRFQEEAV----RLYLCELSLALDYLQQRHIIHRDIKPDNILLDEH-----------------------------APEMF-RSYVEGAPRYSSAVDWWSLGVTAYELLRGWRPYEIHSSTTIDEIL--QILDTKSVHYSSCWSQEMASLLRKLLC</Hsp_qseq>
      <Hsp_hseq>EIQIMATLNKNSQENILKLLDFFEDDDYYYIETPVHGETGSIDLFDVIEFKKDMVEHEAKLVFKQVVASIKHLHDQGIVHRDIKDENVIVDSHGFVKLIDFGSAAYIKSGPFDVFVGTMDYAAPEVLGGSSYKGKPQ-----DIWALGVLLYTIIYKENPY-----YNIDEILEGELRFDKSEHV----SEECISLIKRILT</Hsp_hseq>
      <Hsp_midline>E+QIM  L      N+     F +++D + +   + G      L     F+++ V    +L   ++  ++ +L  + I+HRDIK +N+++D H                             APE+   S  +G P+     D W+LGV  Y ++    PY       IDEIL  ++   KS H     S+E  SL++++L </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YOR061W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:441534:442553:1 gene:YOR061W transcript:YOR061W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA2 description:Alpha&apos; catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000005587]</Hit_def>
  <Hit_accession>YOR061W</Hit_accession>
  <Hit_len>339</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>45.0542</Hsp_bit-score>
      <Hsp_score>105</Hsp_score>
      <Hsp_evalue>7.82458e-06</Hsp_evalue>
      <Hsp_query-from>55</Hsp_query-from>
      <Hsp_query-to>360</Hsp_query-to>
      <Hsp_hit-from>71</Hsp_hit-from>
      <Hsp_hit-to>176</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>109</Hsp_align-len>
      <Hsp_qseq>MNKQVCIERD----EVRNVFRELQIMQELEHT-FLVNLWYSFQDEEDMF--MVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLD</Hsp_qseq>
      <Hsp_hseq>VNNQKCVIKVLKPVKMKKIYRELKILTNLTGGPNVVGLYDIVQDADSKIPALIFEEIKNVDFR---TLYPTFKLPDIQYYFTQLLIALDYCHSMGIMHRDVKPQNVMID</Hsp_hseq>
      <Hsp_midline>+N Q C+ +     +++ ++REL+I+  L     +V L+   QD +     ++ + +   D R        F+   ++ Y  +L +ALDY     I+HRD+KP N+++D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>89</Statistics_hsp-len>
      <Statistics_eff-space>507213406</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0041570-RA transcript Note:&quot;Similar to Wbp1 WW domain-binding protein 1 (Mus musculus)&quot; offset:0 AED:0.27 eAED:0.29 QI:0|0.5|0.33|1|0|0.33|3|1468|389</Iteration_query-def>
  <Iteration_query-len>2638</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1770735527</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0018600-RA transcript Note:&quot;Similar to ANKLE1 Ankyrin repeat and LEM domain-containing protein 1 (Homo sapiens)&quot; offset:0 AED:0.18 eAED:0.18 QI:0|0.8|0.5|1|0|0|6|336|714</Iteration_query-def>
  <Iteration_query-len>2481</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>98</Statistics_hsp-len>
      <Statistics_eff-space>1652837643</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0021509-RA transcript Note:&quot;Similar to Atf5 Cyclic AMP-dependent transcription factor ATF-5 (Mus musculus)&quot; offset:523 AED:0.25 eAED:0.25 QI:523|1|0.6|1|0.25|0.6|5|1170|388</Iteration_query-def>
  <Iteration_query-len>2860</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>99</Statistics_hsp-len>
      <Statistics_eff-space>1930609618</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0010190-RA transcript Note:&quot;Similar to NLRP10 NACHT, LRR and PYD domains-containing protein 10 (Homo sapiens)&quot; offset:0 AED:0.64 eAED:0.92 QI:0|0|0|0.66|0|0.66|3|0|267</Iteration_query-def>
  <Iteration_query-len>804</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>88</Statistics_hsp-len>
      <Statistics_eff-space>419988060</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052381-RA transcript Note:&quot;Similar to bora Protein aurora borealis (Danio rerio)&quot; offset:761 AED:0.25 eAED:0.25 QI:761|0.85|1|1|0|0|15|185|725</Iteration_query-def>
  <Iteration_query-len>3124</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>100</Statistics_hsp-len>
      <Statistics_eff-space>2121077047</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052384-RA transcript Note:&quot;Similar to Fahd1 Acylpyruvase FAHD1, mitochondrial (Mus musculus)&quot; offset:765 AED:0.27 eAED:0.30 QI:765|0.66|0.75|1|1|1|4|0|145</Iteration_query-def>
  <Iteration_query-len>1203</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YNL168C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:318030:318809:-1 gene:YNL168C transcript:YNL168C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP41 description:Putative protein of unknown function; GFP-fusion protein is induced in response to the DNA-damaging agent MMS; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [Source:SGD;Acc:S000005112]</Hit_def>
  <Hit_accession>YNL168C</Hit_accession>
  <Hit_len>259</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.9745</Hsp_bit-score>
      <Hsp_score>232</Hsp_score>
      <Hsp_evalue>1.53117e-22</Hsp_evalue>
      <Hsp_query-from>811</Hsp_query-from>
      <Hsp_query-to>1155</Hsp_query-to>
      <Hsp_hit-from>4</Hsp_hit-from>
      <Hsp_hit-to>144</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>48</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>141</Hsp_align-len>
      <Hsp_qseq>RFWERGRKAVCVGRNYAEHARELNNPLPQEPVLFLKPPTAYVR-------EQGRPLRA-------------PWFC---SSLHHEVELGVVVGRAGSCISQAA---AMEHVAGYALCLDMTARDTQEACKSKGLPWTLAKEW</Hsp_qseq>
      <Hsp_hseq>NYLKAARKIICIGRNYAAHIKELNNSTPKQPFFFLKPTSSIVTPLSSSLVKTTRPANSTFNGLNEDGTNPGPIFIPRGVKVHHEIELALIVSKHLSNVTKMKPEEVYDSISGVALALDLTARNVQDEAKKKGLPWTISKGF</Hsp_hseq>
      <Hsp_midline> + +  RK +C+GRNYA H +ELNN  P++P  FLKP ++ V        +  RP  +             P F      +HHE+EL ++V +  S +++       + ++G AL LD+TAR+ Q+  K KGLPWT++K +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>92</Statistics_hsp-len>
      <Statistics_eff-space>712821903</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0052388-RA transcript Note:&quot;Similar to nrm Nurim (Xenopus laevis)&quot; offset:0 AED:0.27 eAED:0.27 QI:0|0|0|0.5|1|1|4|0|275</Iteration_query-def>
  <Iteration_query-len>828</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>88</Statistics_hsp-len>
      <Statistics_eff-space>438654196</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0041577-RA transcript Note:&quot;Similar to SDR39U1 Epimerase family protein SDR39U1 (Homo sapiens)&quot; offset:0 AED:0.03 eAED:0.03 QI:0|-1|0|1|-1|1|1|0|297</Iteration_query-def>
  <Iteration_query-len>894</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>89</Statistics_hsp-len>
      <Statistics_eff-space>486273403</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

