<?xml version="1.0"?>
<!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "http://www.ncbi.nlm.nih.gov/dtd/NCBI_BlastOutput.dtd">
<BlastOutput>
  <BlastOutput_program>blastx</BlastOutput_program>
  <BlastOutput_version>BLASTX 2.10.0+</BlastOutput_version>
  <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&amp;auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), &quot;Gapped BLAST and PSI-BLAST: a new generation of protein database search programs&quot;, Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
  <BlastOutput_db>/home/smr/dbs/ensembl/release-100/Saccharomyces_cerevisiae.R64-1-1.pep.all.fa</BlastOutput_db>
  <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
  <BlastOutput_query-def>PMZ_0054764-RA transcript Note:&quot;Similar to Parapinopsin (Ictalurus punctatus)&quot; offset:0 AED:0.34 eAED:0.34 QI:0|0|0|0.5|1|1|6|0|290</BlastOutput_query-def>
  <BlastOutput_query-len>873</BlastOutput_query-len>
  <BlastOutput_param>
    <Parameters>
      <Parameters_matrix>BLOSUM62</Parameters_matrix>
      <Parameters_expect>1e-05</Parameters_expect>
      <Parameters_gap-open>11</Parameters_gap-open>
      <Parameters_gap-extend>1</Parameters_gap-extend>
      <Parameters_filter>L;</Parameters_filter>
    </Parameters>
  </BlastOutput_param>
<BlastOutput_iterations>
<Iteration>
  <Iteration_iter-num>1</Iteration_iter-num>
  <Iteration_query-ID>Query_1</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054764-RA transcript Note:&quot;Similar to Parapinopsin (Ictalurus punctatus)&quot; offset:0 AED:0.34 eAED:0.34 QI:0|0|0|0.5|1|1|6|0|290</Iteration_query-def>
  <Iteration_query-len>873</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>89</Statistics_hsp-len>
      <Statistics_eff-space>469986734</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>2</Iteration_iter-num>
  <Iteration_query-ID>Query_2</Iteration_query-ID>
  <Iteration_query-def>PMZ_0030534-RA transcript Note:&quot;Similar to NET1 Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.5|0.55|9|0|386</Iteration_query-def>
  <Iteration_query-len>1161</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>684786232</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>3</Iteration_iter-num>
  <Iteration_query-ID>Query_3</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054765-RA transcript Note:&quot;Similar to rft1 Protein RFT1 homolog (Xenopus tropicalis)&quot; offset:546 AED:0.24 eAED:0.25 QI:546|0.84|0.85|1|0.61|0.71|14|0|483</Iteration_query-def>
  <Iteration_query-len>1998</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YBL020W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:182401:184125:1 gene:YBL020W transcript:YBL020W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RFT1 description:Membrane protein required for translocation of Man5GlcNac2-PP-Dol; required for translocation of Man5GlcNac2-PP-Dol from the cytoplasmic side to the lumenal side of the ER membrane but is not the flippase; mutation is suppressed by expression of human p53 protein; essential gene [Source:SGD;Acc:S000000116]</Hit_def>
  <Hit_accession>YBL020W</Hit_accession>
  <Hit_len>574</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>87.0409</Hsp_bit-score>
      <Hsp_score>214</Hsp_score>
      <Hsp_evalue>2.49366e-18</Hsp_evalue>
      <Hsp_query-from>529</Hsp_query-from>
      <Hsp_query-to>1878</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>496</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>115</Hsp_identity>
      <Hsp_positive>231</Hsp_positive>
      <Hsp_gaps>71</Hsp_gaps>
      <Hsp_align-len>508</Hsp_align-len>
      <Hsp_qseq>GHRATAMASDTTKALQGASTLAIYNVLLQVSFRVVTFVLNAFILRHLSKEVLGVVNVRLTLLYSTTVFLAREAFRRACLSRGSSAD--------------------WRRVINL----LWMAVPLGAA-CAGALGYVWARWLEAPDAKHXXXXXXXXXXXXXXXXXELLSEPLWVLAQAHMFVRLRVCAESLALGSRSILTVVLVFLVPH----------------WGLWVFALAQLMYAVVLSICYY----------VYFTLYIGSTAAKDSHFPISSVRQMFFTWGTQPFEWALVTLTRSFLMQSFLKQLLTEGEKYIMTFFNVLNFGDQGIYDVVNNLGSMVPRFVFLPIEDSFYVFFARSLIRG-----KIAMQQNESLLKLVLLIGVTVLTFGFXXXXXXXXXXXXXXXXXXXXXXXXRWYSAYVLFLALNGITECFVFAAMEQSEVDRYNMRXXXXXXXXXXXXYALTR--AFGSVGFVLANCLNMALRLASSLKFIAAYFRD</Hsp_qseq>
      <Hsp_hseq>AKKNSQLPSTSEQILERSTTGATFLMMGQLFTKLVTFILNNLLIRFLSPRIFGITAF-LEFIQGTVLFFSRDAIRLSTLRISDSGNGIIDDDDEEEYQETHYKSKVLQTAVNFAYIPFWIGFPLSIGLIAWQYRNINAYFITLPFFR------WSIFLIWLSIIVELLSEPFFIVNQFMLNYAARSRFESIAVTTGCIVNFIVVYAVQQSRYPMGVVTSDIDKEGIAILAFALGKLAHSITLLACYYWDYLKNFKPKKLFSTRLTKIKTRENN----ELKKGYPKSTSYFFQNDILQHFKKVYFQLCFKHLLTEGDKLIIN--SLCTVEEQGIYALLSNYGSLLTRLLFAPIEESLRLFLARLLSSHNPKNLKLSIEVLVNLTRFYIYLSLMIIVFGPANSSFLLQFLIGSKWSTTSVLDTIRVYCFYIPFLSLNGIFEAFFQSVATGDQILKHSYFMMAFSGIFLLNSWLLIEKLKLSIEGLILSNIINMVLRILYCGVFLNKFHRE</Hsp_hseq>
      <Hsp_midline>  + + + S + + L+ ++T A + ++ Q+  ++VTF+LN  ++R LS  + G+    L  +  T +F +R+A R + L    S +                     +  +N      W+  PL     A     + A ++  P  +       +++   +S +VELLSEP +++ Q  +    R   ES+A+ +  I+  ++V+ V                    +  FAL +L +++ L  CYY            F+  +     ++++     +++ +    +  F+  ++   +    Q   K LLTEG+K I+   ++    +QGIY +++N GS++ R +F PIE+S  +F AR L        K++++   +L +  + + + ++ FG + S   L    GS  S++     +R Y  Y+ FL+LNGI E F  +     ++ +++  ++  S +FL+ S+ L         G +L+N +NM LR+     F+  + R+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>96</Statistics_hsp-len>
      <Statistics_eff-space>1299866190</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>4</Iteration_iter-num>
  <Iteration_query-ID>Query_4</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054767-RA transcript Note:&quot;Similar to MCM10 Protein MCM10 homolog (Homo sapiens)&quot; offset:623 AED:0.07 eAED:0.07 QI:623|0.82|0.83|1|0.41|0.33|18|1173|851</Iteration_query-def>
  <Iteration_query-len>4352</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YIL150C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:61013:62728:-1 gene:YIL150C transcript:YIL150C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCM10 description:Essential chromatin-associated protein; involved in initiation of DNA replication; required for association of MCM2-7 complex with replication origins; required to stabilize catalytic subunit of DNA polymerase-alpha; self-associates through its N-terminal domain [Source:SGD;Acc:S000001412]</Hit_def>
  <Hit_accession>YIL150C</Hit_accession>
  <Hit_len>571</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>74.7146</Hsp_bit-score>
      <Hsp_score>182</Hsp_score>
      <Hsp_evalue>5.91926e-14</Hsp_evalue>
      <Hsp_query-from>1395</Hsp_query-from>
      <Hsp_query-to>1982</Hsp_query-to>
      <Hsp_hit-from>155</Hsp_hit-from>
      <Hsp_hit-to>360</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>104</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>207</Hsp_align-len>
      <Hsp_qseq>TEVEKYSGFRIRRPLISSVDMERRMAGRRMIRLSQLPDKITRDSL---DNIDWVTIGVIVHKHTPQSVSSGKTFSVWRLMDLKNMEVSVSLLLFGEVH-KQHWKTDQGFVVGLLNPTLM--KPKEGYN---ELSISVDHPQKVML-MGEAKDLGTCRAA-KRNGDPCTQLINLMEGEFCQFHVQSQYRKMSSRRSELQAGFTGREPT</Hsp_qseq>
      <Hsp_hseq>NELESFSNLWVKKRYIPEDDLKRALHEIKILRLGKLFAKIRPPKFQEPEYANWATVGLISHKSDIKFTSSEKPVKFF-MFTITDFQHTLDVYIFGKKGVERYYNLRLGDVIAILNPEVLPWRPSGRGNFIKSFNLRISHDFKCILEIGSSRDLGWCPIVNKKTHKKCGSPINISLHKCCDYHREVQFRGTSAKRIELNGGYALGAPT</Hsp_hseq>
      <Hsp_midline> E+E +S   +++  I   D++R +   +++RL +L  KI        +  +W T+G+I HK   +  SS K    + +  + + + ++ + +FG+   ++++    G V+ +LNP ++  +P    N     ++ + H  K +L +G ++DLG C    K+    C   IN+   + C +H + Q+R  S++R EL  G+    PT</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>102</Statistics_hsp-len>
      <Statistics_eff-space>3020688716</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>5</Iteration_iter-num>
  <Iteration_query-ID>Query_5</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054769-RA transcript Note:&quot;Similar to MAPK14 Mitogen-activated protein kinase 14 (Pan troglodytes)&quot; offset:335 AED:0.27 eAED:0.27 QI:335|0.8|0.81|0.90|0.5|0.63|11|0|362</Iteration_query-def>
  <Iteration_query-len>1424</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>299.286</Hsp_bit-score>
      <Hsp_score>765</Hsp_score>
      <Hsp_evalue>1.10105e-97</Hsp_evalue>
      <Hsp_query-from>459</Hsp_query-from>
      <Hsp_query-to>1415</Hsp_query-to>
      <Hsp_hit-from>5</Hsp_hit-from>
      <Hsp_hit-to>333</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>156</Hsp_identity>
      <Hsp_positive>211</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>340</Hsp_align-len>
      <Hsp_qseq>EGFCRQELNKTVWEVPRRYVNLTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKRTYRELRLLKHMKHENVIGLMDVFTPNSSLEEFDDLIRNVASWHVPSCEGSTL-------PVSVN-------------SYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSLPYTQKRDFKDVFLGANPLVVDLLERMLVLDTDQRITAAEALVHQYFAQYHX-XXXXXXXXXYDQSFENQEFPVEEWR</Hsp_qseq>
      <Hsp_hseq>EEFIRTQIFGTVFEITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFL--SPLEDI---------YFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENTLKFVTSLPHRDPIPFSERFKTVEPDAVDLLEKMLVFDPKKRITAADALAHPYSAPYHDPTDEPVADAKFDWHFNDADLPVDTWR</Hsp_hseq>
      <Hsp_midline>E F R ++  TV+E+  RY +L  VG GA+G VCS+ DT T   VA+KK+ +PF + + AKRTYREL+LLKH++HEN+I L D+F   S LE+          + V   +G+ L       P+                 Y+HSAG+IHRDLKPSN+ +NE+C+LKI DFGLAR  D +MTGYV+TR+YRAPEIML W  Y+  VDIWS GCI AE++ G+ LFPG DH++Q   I  L G+PP+ +I+ + S+    ++ SLP+     F + F    P  VDLLE+MLV D  +RITAA+AL H Y A YHD  D+      +D  F + + PV+ WR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>230.72</Hsp_bit-score>
      <Hsp_score>587</Hsp_score>
      <Hsp_evalue>1.22747e-70</Hsp_evalue>
      <Hsp_query-from>495</Hsp_query-from>
      <Hsp_query-to>1337</Hsp_query-to>
      <Hsp_hit-from>17</Hsp_hit-from>
      <Hsp_hit-to>322</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>124</Hsp_identity>
      <Hsp_positive>179</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>306</Hsp_align-len>
      <Hsp_qseq>WEVPRRYVNLTSVGSGAYGSVCSS--LDTKTGMKVAVKKLSRPFQSVIHAKRTYRELRLLKHMK-HENVIGLMD---VFTPNSSLE-----------EFDDLIRNVASWHVPSCEGSTLPVSVN-SYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDE-------MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSLPYTQKRDFKDVFLGANPLVVDLLERMLVLDTDQRITAAEALVHQYFAQYH</Hsp_qseq>
      <Hsp_hseq>FSVDKRFQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPYLSIWH</Hsp_hseq>
      <Hsp_midline>+ V +R+  +  +G GAYG VCS+   +      VA+KK++  F   +  KR+ REL+LL+H + H+N+  L D   VF P+ S+            +   +I++         +  T  +     YIHSA ++HRDLKP NL VN DC+LKI DFGLAR   +        +T YVATRWYRAPEIML++  Y + +D+WS GCI+AE L G+ +F G D++NQL +ILQ+ GTPP   + R+ SK  ++YI  L +  K  F +++  AN   +DLLE+ML  D  +RIT  EAL H Y + +H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>226.868</Hsp_bit-score>
      <Hsp_score>577</Hsp_score>
      <Hsp_evalue>1.3658e-70</Hsp_evalue>
      <Hsp_query-from>495</Hsp_query-from>
      <Hsp_query-to>1337</Hsp_query-to>
      <Hsp_hit-from>7</Hsp_hit-from>
      <Hsp_hit-to>317</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>129</Hsp_identity>
      <Hsp_positive>192</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>312</Hsp_align-len>
      <Hsp_qseq>WEVPRRYVNLTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKRTYRELRLLKHM-KHENVIGLMDVFTPNSS--------LEEF--DDLIRNVASWHVPSCEGSTLPVSVNSY--------IHSAGIIHRDLKPSNLAVNEDCELKILDFGLAR---HADDE-------MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSLPYTQKRDFKDVF--LGANPLVVDLLERMLVLDTDQRITAAEALVHQYFAQYH</Hsp_qseq>
      <Hsp_hseq>FDIPSQYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKI-QPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIANLPMRPPLPWETVWSKTDLNPDMIDLLDKMLQFNPDKRISAAEALRHPYLAMYH</Hsp_hseq>
      <Hsp_midline>+++P +Y  +  +G GAYG+VCS++   +G+KVA+KK+ +PF   +   RT RE++LL++  +HEN+I ++D   P S         +EE    DL + + + +      S   V   +Y        IHSA +IHRD+KPSNL +N +C+LK+ DFGLAR    + D        MT YVATRWYRAPEIML +  Y   +DIWS GCI+AE+++G+ LFPG D+ +QL  IL++ GTP     ++++SK A+ YI +LP      ++ V+     NP ++DLL++ML  + D+RI+AAEAL H Y A YH</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>224.942</Hsp_bit-score>
      <Hsp_score>572</Hsp_score>
      <Hsp_evalue>6.67979e-70</Hsp_evalue>
      <Hsp_query-from>501</Hsp_query-from>
      <Hsp_query-to>1337</Hsp_query-to>
      <Hsp_hit-from>1</Hsp_hit-from>
      <Hsp_hit-to>313</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>132</Hsp_identity>
      <Hsp_positive>182</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>317</Hsp_align-len>
      <Hsp_qseq>VPRRYV-NLTS-------VGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKRTYRELRLLKHMKHENVIGLMDVFTPNSSLEEFD-----------DLIRNVASW-----HVPSCEGSTLPVSVNSYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDE-------------MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTP-PQYLIDRMQSKEARNYIQSLPYTQKRDFKDVFLGANPLVVDLLERMLVLDTDQRITAAEALVHQYFAQYH</Hsp_qseq>
      <Hsp_hseq>MPKRIVYNISSDFQLKSLLGEGAYGVVCSATHKPTGEIVAIKKIE-PFDKPLFALRTLREIKILKHFKHENIITIFNIQRPDS-FENFNEVYIIQELMQTDLHRVISTQMLSDDHIQYFIYQTL--RAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHSDNDLRCIESPRAREYIKSLPMYPAAPLEKMFPRVNPKGIDLLQRMLVFDPAKRITAKEALEHPYLQTYH</Hsp_hseq>
      <Hsp_midline>+P+R V N++S       +G GAYG VCS+    TG  VA+KK+  PF   + A RT RE+++LKH KHEN+I + ++  P+S  E F+           DL R +++      H+      TL       +H + +IHRDLKPSNL +N +C+LK+ DFGLAR  D+              MT YVATRWYRAPE+ML    Y++ +D+WS GCI+AEL   R +FPG D+ +QL+ I  + GTP     +  ++S  AR YI+SLP       + +F   NP  +DLL+RMLV D  +RITA EAL H Y   YH</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>203.756</Hsp_bit-score>
      <Hsp_score>517</Hsp_score>
      <Hsp_evalue>6.93731e-61</Hsp_evalue>
      <Hsp_query-from>510</Hsp_query-from>
      <Hsp_query-to>1337</Hsp_query-to>
      <Hsp_hit-from>21</Hsp_hit-from>
      <Hsp_hit-to>322</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>114</Hsp_identity>
      <Hsp_positive>175</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>304</Hsp_align-len>
      <Hsp_qseq>RYVNLTS-VGSGAYGSVCSSLDTKTGMK--VAVKKLSRPFQSVIHAKRTYRELRLLKHMK-HENVIGLMD---VFTPNSSLE-----------EFDDLIRN---VASWHVPSCEGSTLPVSVNSYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLA-------RHADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSLPYTQKRDFKDVFLGANPLVVDLLERMLVLDTDQRITAAEALVHQYFAQYH</Hsp_qseq>
      <Hsp_hseq>KHFHLTGKIGRGSHSLICSSTYTESNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLYEELMECDLSQIIRSEQRLEDAHFQSFIYQIL--CALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIPGRSFESILPGANPEALELLKKMLEFDPKKRITVEDALEHPYLSMWH</Hsp_hseq>
      <Hsp_midline>++ +LT  +G G++  +CSS  T++  +  VA++K+   F + +  KRT REL+LL+H++ H N++ L D   VF PN +L            +   +IR+   +   H  S     L      YIHSA ++H DLKP NL VN DC+LKI +FGL+       +  D  + GY+ + WY+APEI+LN+    + VDIWS GCI+AELL  + +F G D+++ L  ILQ+ GTPP+  +  + S++  NYI        R F+ +  GANP  ++LL++ML  D  +RIT  +AL H Y + +H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>162.54</Hsp_bit-score>
      <Hsp_score>410</Hsp_score>
      <Hsp_evalue>7.20052e-46</Hsp_evalue>
      <Hsp_query-from>501</Hsp_query-from>
      <Hsp_query-to>1331</Hsp_query-to>
      <Hsp_hit-from>34</Hsp_hit-from>
      <Hsp_hit-to>339</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>103</Hsp_identity>
      <Hsp_positive>168</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>306</Hsp_align-len>
      <Hsp_qseq>VPRRYVNLTSVGSGAYGSVCSSL--DTKTGMKVAVKKLSRPFQSVIHAKRTYRELRLLKHMK-HENVIGLMDV----FTPNSSLEEFDDLI-RNVASWHVPSCEGSTLPVSVN--------SYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLAR--HA---------DDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSL--PYTQKRDFKDVFLGANPLVVDLLERMLVLDTDQRITAAEALVHQYFAQ</Hsp_qseq>
      <Hsp_hseq>IPGYYEIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGHKNIVNLIDLEIVTSSPYDGLYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDKDILIKFGTIKAWNLGKNSNNPVYKKIPWSNIFPFASHEAINLIESLLHWDSTHRLNVEQAISHPFLNE</Hsp_hseq>
      <Hsp_midline>+P  Y  +  +G GAYG+VCS          ++AVKK+S  F   I  KR  REL+ +   K H+N++ L+D+     +P   L  + +LI  ++A     S + S   +            YIHSA +IHRDLKP N+    +  LKI DFGLAR  HA            +T YVATRWYRAPE++L+   Y+++VDIW+VGCI+AE    + +F G D ++Q+ +I+++ GTP + ++ +  + +A N  ++   P  +K  + ++F  A+   ++L+E +L  D+  R+   +A+ H +  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>155.606</Hsp_bit-score>
      <Hsp_score>392</Hsp_score>
      <Hsp_evalue>3.34662e-44</Hsp_evalue>
      <Hsp_query-from>513</Hsp_query-from>
      <Hsp_query-to>1331</Hsp_query-to>
      <Hsp_hit-from>8</Hsp_hit-from>
      <Hsp_hit-to>297</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>97</Hsp_identity>
      <Hsp_positive>149</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>296</Hsp_align-len>
      <Hsp_qseq>YVNLTSVGSGAYGSVCSSLDTKTGMK---VAVKKLSRPFQSVIHAKRTYRELRLLKHMKHENVIGLMDVFTPNSS----LEEFDDLIRNVASWHVPSCEGSTLPVSVN-------------SYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDEMTGY---VATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSLPYTQKRDFKDVFLGANPLVVDLLERMLVLDTDQRITAAEALVHQYFAQ</Hsp_qseq>
      <Hsp_hseq>YKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQ----PLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIVY--LPDFKPSFPQWRRKDLSQVVPSLDPRGIDLLDKLLAYDPINRISARRAAIHPYFQE</Hsp_hseq>
      <Hsp_midline>Y  L  VG G YG V  +LD + G     VA+KK+    +         RE+ LLK +K +N++ L D+   ++     + EF DL        +P  +    P+  +             +Y HS  I+HRDLKP NL +N+D  LK+ DFGLAR     +  Y   + T WYRAPE++L    Y+  VD WS+GCI AE+   + +F G   I+Q+ KI ++ GTP + +   +      ++  S P  +++D   V    +P  +DLL+++L  D   RI+A  A +H YF +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>154.836</Hsp_bit-score>
      <Hsp_score>390</Hsp_score>
      <Hsp_evalue>7.75617e-44</Hsp_evalue>
      <Hsp_query-from>510</Hsp_query-from>
      <Hsp_query-to>1337</Hsp_query-to>
      <Hsp_hit-from>6</Hsp_hit-from>
      <Hsp_hit-to>301</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>98</Hsp_identity>
      <Hsp_positive>156</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>300</Hsp_align-len>
      <Hsp_qseq>RYVNLTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKRTYRELRLLKHMKHENVIGLMDVFTPNSSLEEFDDLIRNVASWHVPSCEGSTLPVSVN---------------SYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHAD---DEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARN-YIQSLPYTQKRDFKDVFL--GANPL---VVDLLERMLVLDTDQRITAAEALVHQYFAQYH</Hsp_qseq>
      <Hsp_hseq>QFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPKYNPNIQQRP---PRDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWFAEYY</Hsp_hseq>
      <Hsp_midline>++  L  +G+G Y +V   L+  TG+ VA+K++    +    +    RE+ L+K +KHEN++ L DV    + L    + + N    ++ S      P  +                ++ H   I+HRDLKP NL +N+  +LK+ DFGLAR      +  +  V T WYRAP++++    Y+ ++DIWS GCI+AE++TG+ LFPGT+   QL  I  + GTP + L   +      N  IQ  P    RD + V       PL   ++D L  +L L+ D R++A +AL H +FA+Y+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>144.05</Hsp_bit-score>
      <Hsp_score>362</Hsp_score>
      <Hsp_evalue>7.34593e-40</Hsp_evalue>
      <Hsp_query-from>498</Hsp_query-from>
      <Hsp_query-to>1331</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>292</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>88</Hsp_identity>
      <Hsp_positive>147</Hsp_positive>
      <Hsp_gaps>15</Hsp_gaps>
      <Hsp_align-len>292</Hsp_align-len>
      <Hsp_qseq>EVPRRYVNLTSVGSGAYGSVCSSLDTKTGMKVAVKKL-SRPFQSVIHAKRTYRELRLLKHMKHENVIGLMDVFTPNSSLE--------EFDDLIRNVASWHVPSCEGSTLPVSVNS--YIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARH---ADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSLPYTQKRDFKDVFLGANPLVVDLLERMLVLDTDQRITAAEALVHQYFAQ</Hsp_qseq>
      <Hsp_hseq>KVNMEYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMS-AIREVKYLQEMQHPNVIELIDIFMAYDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDRDWPEVSSFMTYNKLQIYPPPSRDELRKRFIAASEYALDFMCGMLTMNPQKRWTAVQCLESDYFKE</Hsp_hseq>
      <Hsp_midline>+V   Y     VG G Y  V       TG K+A+K++ +  F+  +      RE++ L+ M+H NVI L+D+F    +L         + + +I++ +    P+   + + +++    + H   I+HRDLKP+NL  + D ++K+ DFGLAR      + +T  V TRWYRAPE++    HY   +DIWSVG I AEL+      PG + ++Q+    +  GTP       + S    N +Q  P   + + +  F+ A+   +D +  ML ++  +R TA + L   YF +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>136.346</Hsp_bit-score>
      <Hsp_score>342</Hsp_score>
      <Hsp_evalue>1.83625e-36</Hsp_evalue>
      <Hsp_query-from>531</Hsp_query-from>
      <Hsp_query-to>1331</Hsp_query-to>
      <Hsp_hit-from>45</Hsp_hit-from>
      <Hsp_hit-to>324</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>96</Hsp_identity>
      <Hsp_positive>144</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>291</Hsp_align-len>
      <Hsp_qseq>VGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKR-TYRELRLLKHMKHENVIGLMDVFTPNSSLEE-FDDLI------------RNVASWHVPSCEGST------LPVSVNSYIHSAGIIHRDLKPSNLAVN-EDCELKILDFGLARH--ADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQ-SLPYTQKRDFKDVFLGANPLVVDLLERMLVLDTDQRITAAEALVHQYFAQ</Hsp_qseq>
      <Hsp_hseq>VGHGSFGVVFATVIQETNEKVAIKK-------VLQDKRFKNRELEIMKMLSHINIIDLKYFFYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILGTPSKQEICSMNP----NYMEHKFPQIKPIPLSRVFKKEDDQTVEFLADVLKYDPLERFNALQCLCSPYFDE</Hsp_hseq>
      <Hsp_midline>VG G++G V +++  +T  KVA+KK       V+  KR   REL ++K + H N+I L   F    S +E + +LI            R+      P            L  S+N   H A + HRD+KP NL V+ E   LK+ DFG A+     +    Y+ +R+YRAPE++    +Y   +DIWS GC+MAELL G+ +FPG   I+QLV+I+++ GTP +  I  M      NY++   P  +      VF   +   V+ L  +L  D  +R  A + L   YF +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YDL079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:312951:314748:-1 gene:YDL079C transcript:YDL079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRK1 description:Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication [Source:SGD;Acc:S000002237]</Hit_def>
  <Hit_accession>YDL079C</Hit_accession>
  <Hit_len>501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>128.642</Hsp_bit-score>
      <Hsp_score>322</Hsp_score>
      <Hsp_evalue>8.93481e-33</Hsp_evalue>
      <Hsp_query-from>531</Hsp_query-from>
      <Hsp_query-to>1331</Hsp_query-to>
      <Hsp_hit-from>170</Hsp_hit-from>
      <Hsp_hit-to>449</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>91</Hsp_identity>
      <Hsp_positive>142</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>294</Hsp_align-len>
      <Hsp_qseq>VGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKR-TYRELRLLKHMKHENVIGLMDVFTPNSSLEEFDDLIRNVASWHVPSCEGSTLPVSVN---------------------SYIHSAG-IIHRDLKPSNLAVNEDC-ELKILDFGLAR--HADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQS-LPYTQKRDFKDVFLGANPLVVDLLERMLVLDTDQRITAAEALVHQYFAQ</Hsp_qseq>
      <Hsp_hseq>VGHGSFGVVVTTVIIETNQKVAIKK-------VLQDRRYKNRELETMKMLCHPNTVGLQYYFYEK---DEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKIMGIPTKDEISGMNP----NYEDHVFPNIKPITLAEIFKAEDPDTLDLLTKTLKYHPCERLVPLQCLLSSYFDE</Hsp_hseq>
      <Hsp_midline>VG G++G V +++  +T  KVA+KK       V+  +R   REL  +K + H N +GL   F      +E D++  N+   ++P      L   VN                     +Y+H+   I HRD+KP NL V+      KI DFG A+    D     Y+ +R+YRAPE+M    +Y+  VD+WS  C++AELL G+ LF G   I+QLV+I+++ G P +  I  M      NY     P  +     ++F   +P  +DLL + L     +R+   + L+  YF +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>126.331</Hsp_bit-score>
      <Hsp_score>316</Hsp_score>
      <Hsp_evalue>8.9418e-33</Hsp_evalue>
      <Hsp_query-from>531</Hsp_query-from>
      <Hsp_query-to>1331</Hsp_query-to>
      <Hsp_hit-from>41</Hsp_hit-from>
      <Hsp_hit-to>329</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>87</Hsp_identity>
      <Hsp_positive>143</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>303</Hsp_align-len>
      <Hsp_qseq>VGSGAYGSVCSSLDTKTGMK----VAVKKLSRPFQSVIHAKRTYRELRLLKHMKHENVIGLMDVFTPNSSLEEFDDLIRNVASWHVP-SCEGSTLPVSVNSYI-------------------------HSAGIIHRDLKPSNLAVN-EDCELKILDFGLARHADDEM--TGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSLPY---TQKRDFKDVFLGANPLVVDLLERMLVLDTDQRITAAEALVHQYFAQ</Hsp_qseq>
      <Hsp_hseq>IGRGAFGTVVQAYLTQDKKNWLGPFAIKKVP------AHTEYKSRELQILRIADHPNIVKLQYFFTHLSPQD-------NKVYQHLAMECLPETLQIEINRYVTNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSISYICSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLREIAKLLGPPDKRFI-FFSNPAYDGPLFSKPLFSGSSQQRFEKYFGHSGPDGIDLLMKILVYEPQQRLSPRRILAHQFFNE</Hsp_hseq>
      <Hsp_midline>+G GA+G+V  +  T+         A+KK+        H +   REL++L+   H N++ L   FT  S  +       N    H+   C   TL + +N Y+                         H  G+ HRD+KPSN+ V+ E   LKI DFG A+  +       Y+ +R+YRAPE+++    Y   +DIW +GC+M E+L G+ +F G + + QL +I +L G P +  I    +      + S P    + ++ F+  F  + P  +DLL ++LV +  QR++    L HQ+F +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>120.168</Hsp_bit-score>
      <Hsp_score>300</Hsp_score>
      <Hsp_evalue>7.69793e-30</Hsp_evalue>
      <Hsp_query-from>513</Hsp_query-from>
      <Hsp_query-to>1331</Hsp_query-to>
      <Hsp_hit-from>183</Hsp_hit-from>
      <Hsp_hit-to>471</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>84</Hsp_identity>
      <Hsp_positive>140</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>297</Hsp_align-len>
      <Hsp_qseq>YVNLTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKRTYRELRLLKHMKHENVIGLMDVFTPNSS----LEEFDD-------LIRNVASWHVPSCEGSTLPVSVNSYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADD--EMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTP-----------PQYLIDRMQSKEARNYIQSLPYTQKRDFKDVFLGANPLVVDLLERMLVLDTDQRITAAEALVHQYFAQ</Hsp_qseq>
      <Hsp_hseq>YLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNVSTIKEIMVESQKTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKMNSRADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTPTINSWPTLYDMPWFFM--IMPQQTTKYVNN--FSEK--FKSVLPSSKCLQLAI--NLLCYDQTKRFSATEALQSDYFKE</Hsp_hseq>
      <Hsp_midline>Y+ +  VG G YG V  + +T T   VA+KKL    +       + RE++LL+   H NV  + ++   +      + E+ D       L + V   H          +    Y+H   I+HRD+K SN+ ++    LKI DFGLAR  +   + T  V T WYR PE++L   +Y   VD+W  GC++ EL     +F G++ + Q+  I ++ GTP           P + +  +  ++   Y+ +  +++K  FK V   +  L + +   +L  D  +R +A EAL   YF +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>115.931</Hsp_bit-score>
      <Hsp_score>289</Hsp_score>
      <Hsp_evalue>3.97689e-29</Hsp_evalue>
      <Hsp_query-from>531</Hsp_query-from>
      <Hsp_query-to>1325</Hsp_query-to>
      <Hsp_hit-from>47</Hsp_hit-from>
      <Hsp_hit-to>329</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>83</Hsp_identity>
      <Hsp_positive>143</Hsp_positive>
      <Hsp_gaps>40</Hsp_gaps>
      <Hsp_align-len>294</Hsp_align-len>
      <Hsp_qseq>VGSGAYGSVCSSLDTKTGMK----VAVKKLSRPFQSVIHAKRTYRELRLLKHMKHENVIGLMDVFTPNSSLEEFDDLI-RNVASWHVPSC----------EGSTLPVS-VNSY----------IHSAGIIHRDLKPSNLAVNEDCEL-KILDFGLARHADD--EMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSLPYTQKRDFKDVFLGANPLVVDLLERMLVLDTDQRITAAEALVHQYF</Hsp_qseq>
      <Hsp_hseq>IGHGSFGTVTQSILSSNSIEWLGPYAIKRV------VKSPKVQSLELEILQNIRHPNLVTLEFFFESHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGIAKVCDFGSAQRLDDNTELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPLFKGDSANSQLEEIAKLLGRFPKSSI-----KNSQELQDSLNDQKFKKFMHWFPSIEFFDVEFLLKVLTYDATERCDARQLMAHEFF</Hsp_hseq>
      <Hsp_midline>+G G++G+V  S+ +   ++     A+K++      V   K    EL +L++++H N++ L   F  + + ++   L  +N    ++P             GS +P   +  Y          +HS  I H DLKPSN+ +     + K+ DFG A+  DD  E+  Y  +R+YRAPE++LN   Y   +DIWS+GCI+ E++ G+ LF G    +QL +I +L G  P+  I     K ++    SL   + + F   F       V+ L ++L  D  +R  A + + H++F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YOR061W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:441534:442553:1 gene:YOR061W transcript:YOR061W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA2 description:Alpha&apos; catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000005587]</Hit_def>
  <Hit_accession>YOR061W</Hit_accession>
  <Hit_len>339</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>114.39</Hsp_bit-score>
      <Hsp_score>285</Hsp_score>
      <Hsp_evalue>8.22997e-29</Hsp_evalue>
      <Hsp_query-from>495</Hsp_query-from>
      <Hsp_query-to>1325</Hsp_query-to>
      <Hsp_hit-from>44</Hsp_hit-from>
      <Hsp_hit-to>334</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>92</Hsp_identity>
      <Hsp_positive>157</Hsp_positive>
      <Hsp_gaps>56</Hsp_gaps>
      <Hsp_align-len>312</Hsp_align-len>
      <Hsp_qseq>WEVPRRYVNLTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKRTYRELRLLKHMKH-ENVIGLMDVF------TPNSSLEEFDDLIRNV------ASWHVPSCE--GSTLPVSVNSYIHSAGIIHRDLKPSNLAVN-EDCELKILDFGLAR--HADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRT-LFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQS----LPYTQKRDFKDV-------FLG-----ANPLVVDLLERMLVLDTDQRITAAEALVHQYF</Hsp_qseq>
      <Hsp_hseq>WGKISNYEIINKIGRGKYSEVFSGRCIVNNQKCVIKVL-KP----VKMKKIYRELKILTNLTGGPNVVGLYDIVQDADSKIPALIFEE----IKNVDFRTLYPTFKLPDIQYYFTQLLIALD-YCHSMGIMHRDVKPQNVMIDPTERKLRLIDWGLAEFYHPGVDYNVRVASRYHKGPELLVNLNQYDYSLDLWSVGCMLAAIVFKKEPFFKGSSNPDQLVKIATVLGT-----------KELLGYLGKYGLHLPSEYDNIMRDFTKKSWTHFITSETKLAVPEVVDLIDNLLRYDHQERLTAKEAMDHKFF</Hsp_hseq>
      <Hsp_midline>W     Y  +  +G G Y  V S        K  +K L +P    +  K+ YREL++L ++    NV+GL D+        P    EE    I+NV       ++ +P  +   + L ++++ Y HS GI+HRD+KP N+ ++  + +L+++D+GLA   H   +    VA+R+++ PE+++N   Y+ ++D+WSVGC++A ++  +   F G+ + +QLVKI  + GT           KE   Y+      LP       +D        F+      A P VVDL++ +L  D  +R+TA EA+ H++F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>113.62</Hsp_bit-score>
      <Hsp_score>283</Hsp_score>
      <Hsp_evalue>2.71002e-27</Hsp_evalue>
      <Hsp_query-from>531</Hsp_query-from>
      <Hsp_query-to>1331</Hsp_query-to>
      <Hsp_hit-from>66</Hsp_hit-from>
      <Hsp_hit-to>368</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>85</Hsp_identity>
      <Hsp_positive>138</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>307</Hsp_align-len>
      <Hsp_qseq>VGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKRTYRELRLLKHMKHENVIGLMDVF---TP---NSSLEEFDDLIRNVASWHVPSCEGSTLPVSVN-----------------SYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLAR---------------HADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQ--YLIDRMQSKEARNYIQSLPYTQKRDFKDVFLGANPLVVDLLERMLVLDTDQRITAAEALVHQYFAQ</Hsp_qseq>
      <Hsp_hseq>LGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTEEDWAVARYLPGAELTTTNYKPTLRERFGK--YLSETGL--DFLGQLLALDPYKRLTAMSAKHHPWFKE</Hsp_hseq>
      <Hsp_midline>+G G +G V   +  +T  +VA+KK+    +  +      RE+ +LK + H+N+I L+++    +P   N++          +  + V    G      +N                 +YIH A  +HRD+K +N+ ++ +  LK+ DFGLAR                +  + T  V TRWYRAPE++L    Y   VDIW VGC+ AE    + +  G   I+Q   I +L GTP +  + + R             P  ++R  K  +L    L  D L ++L LD  +R+TA  A  H +F +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>111.694</Hsp_bit-score>
      <Hsp_score>278</Hsp_score>
      <Hsp_evalue>6.96306e-27</Hsp_evalue>
      <Hsp_query-from>816</Hsp_query-from>
      <Hsp_query-to>1331</Hsp_query-to>
      <Hsp_hit-from>275</Hsp_hit-from>
      <Hsp_hit-to>465</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>102</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>193</Hsp_align-len>
      <Hsp_qseq>SYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDEM----TG--YVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTD-----------HINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSLPYTQKRDFKDVFL----GANPLVVDLLERMLVLDTDQRITAAEALVHQYFAQ</Hsp_qseq>
      <Hsp_hseq>SYLHQNWVLHRDLKPANIMVTIDGCVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELIGLQPIFKGEEAKLDSKKTVPFQVNQLQRILEVLGTPDQKIWPYLEKYPEYDQITKFP--KYRDNLATWYHSAGGRDKHALSLLYHLLNYDPIKRIDAFNALEHKYFTE</Hsp_hseq>
      <Hsp_midline>SY+H   ++HRDLKP+N+ V  D  +KI D GLAR   + +    TG   V T WYRAPE++L   HY   VD+WSVGCI AEL+  + +F G +            +NQL +IL++ GTP Q +   ++     + I   P  + RD    +     G +   + LL  +L  D  +RI A  AL H+YF +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YIL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:287790:288908:-1 gene:YIL035C transcript:YIL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA1 description:Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000001297]</Hit_def>
  <Hit_accession>YIL035C</Hit_accession>
  <Hit_len>372</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>104.375</Hsp_bit-score>
      <Hsp_score>259</Hsp_score>
      <Hsp_evalue>4.10171e-25</Hsp_evalue>
      <Hsp_query-from>672</Hsp_query-from>
      <Hsp_query-to>1328</Hsp_query-to>
      <Hsp_hit-from>127</Hsp_hit-from>
      <Hsp_hit-to>364</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>129</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>239</Hsp_align-len>
      <Hsp_qseq>HMKHENVIGLMDVF------TPNSSLEEFDDLIRNVASWHVPSCEGSTLPVSVN---SYIHSAGIIHRDLKPSNLAVN-EDCELKILDFGLAR--HADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRT-LFPGTDHINQLVKILQLTGTP--PQYLIDRMQSKEARNYIQSLPYTQK---RDFKD--VFLGANPLVVDLLERMLVLDTDQRITAAEALVHQYFA</Hsp_qseq>
      <Hsp_hseq>HNGHANIIHLFDIIKDPISKTPALVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLL-KYEITLPREFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWFA</Hsp_hseq>
      <Hsp_midline>H  H N+I L D+       TP    E  D++   +    +   E       +     Y HS GI+HRD+KP N+ ++ ++ +L+++D+GLA   H + E    VA+R+++ PE+++++  Y+ ++D+WS G ++A ++  R   F GT + +QLVKI+++ GT    +YL+ + +    R +     Y +K   R   D    L  N  ++DL++ +L  D  +R+TA EA+ H +FA</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>105.916</Hsp_bit-score>
      <Hsp_score>263</Hsp_score>
      <Hsp_evalue>7.36639e-25</Hsp_evalue>
      <Hsp_query-from>819</Hsp_query-from>
      <Hsp_query-to>1127</Hsp_query-to>
      <Hsp_hit-from>183</Hsp_hit-from>
      <Hsp_hit-to>304</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>122</Hsp_align-len>
      <Hsp_qseq>YIHSAGIIHRDLKPSNLAVNEDCE-----------------LKILDFGLARHADDE--MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTP</Hsp_qseq>
      <Hsp_hseq>HIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVENKNPYTAYVSTRWYRSPEILLRSGYYSKPLDIWAFGCVAVEVTVFRALFPGANEIDQIWKILEVLGTP</Hsp_hseq>
      <Hsp_midline>+IH     HRDLKP N+ +    +                 +K+ DFGLARH +++   T YV+TRWYR+PEI+L   +Y++ +DIW+ GC+  E+   R LFPG + I+Q+ KIL++ GTP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>105.145</Hsp_bit-score>
      <Hsp_score>261</Hsp_score>
      <Hsp_evalue>2.0328e-24</Hsp_evalue>
      <Hsp_query-from>498</Hsp_query-from>
      <Hsp_query-to>1145</Hsp_query-to>
      <Hsp_hit-from>364</Hsp_hit-from>
      <Hsp_hit-to>595</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>243</Hsp_align-len>
      <Hsp_qseq>EVPRRYVNLTSVGSGAYGSV--CSSLDTKTGMKVAVKKLSRPF--QSVIHAK------------RTYRELRLLKHMKHENVIGLMDVFTPNSSLEEFDD---------LIRNVASWHVPSCEGSTLPVSVNSYIHSAGIIHRDLKPSN--LAVNEDCELKILDFGLARHADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLID</Hsp_qseq>
      <Hsp_hseq>EQNRKYLVLDILGQGTFGQVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKNHLCLVFELLSNNLYELLKQNKFHGLSIQLIRTFTTQILDSL----------CVLKESKLIHCDLKPENILLCAPDKPELKIIDFGSSCEEARTVYTYIQSRFYRAPEIILG-IPYSTSIDMWSLGCIVAELFLGIPIFPGASEYNQLTRIIDTLGYPPSWMID</Hsp_hseq>
      <Hsp_midline>E  R+Y+ L  +G G +G V  C +L TK  + V V K    +  QS+  AK              +  LR+     H+N + L+     N+  E             LIR   +  + S             +  + +IH DLKP N  L   +  ELKI+DFG +      +  Y+ +R+YRAPEI+L  + Y+ ++D+WS+GCI+AEL  G  +FPG    NQL +I+   G PP ++ID</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>98.2117</Hsp_bit-score>
      <Hsp_score>243</Hsp_score>
      <Hsp_evalue>3.00792e-22</Hsp_evalue>
      <Hsp_query-from>504</Hsp_query-from>
      <Hsp_query-to>1331</Hsp_query-to>
      <Hsp_hit-from>8</Hsp_hit-from>
      <Hsp_hit-to>295</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>135</Hsp_positive>
      <Hsp_gaps>64</Hsp_gaps>
      <Hsp_align-len>314</Hsp_align-len>
      <Hsp_qseq>PRRYVNLTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKRTY-----RELRLLKHMKHENVIGLMDVFTPNSSL---------EEFDDLIRNVASWH-VPSCEGSTLPVSVNSYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDEMTG--------------------YVATRWYRAPEIMLNWMHYNQT---VDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSLPYTQKRDFKDVFLGANPLVVDLLERMLVLDTDQRITAAEALVHQYFAQ</Hsp_qseq>
      <Hsp_hseq>PHDFIFKEELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLL----YNQCGYGSDIWALGCMIYQFVQGQPPFRGENELKTFEKIVAL----------------------DYPWGPNNRINNSTSPINPLVINLVQKILVIEVNERISLEQIKRHPYFSK</Hsp_hseq>
      <Hsp_midline>P  ++    +G G+Y +V  +LD K+  K+   K+      +  AK  Y       + LL    H  +I L   F    +L          E   L+  + +++ + +   +   +    +IHS GIIHRDLKP N+ ++ D  L I DFG A   D  ++G                    +V T  Y +PE++L    YNQ     DIW++GC++ + + G+  F G + +    KI+ L                        P+       +     NPLV++L++++LV++ ++RI+  +   H YF++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>94.7449</Hsp_bit-score>
      <Hsp_score>234</Hsp_score>
      <Hsp_evalue>4.07477e-21</Hsp_evalue>
      <Hsp_query-from>531</Hsp_query-from>
      <Hsp_query-to>1316</Hsp_query-to>
      <Hsp_hit-from>204</Hsp_hit-from>
      <Hsp_hit-to>463</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>87</Hsp_identity>
      <Hsp_positive>132</Hsp_positive>
      <Hsp_gaps>56</Hsp_gaps>
      <Hsp_align-len>289</Hsp_align-len>
      <Hsp_qseq>VGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKRTYRELRLLKHMKHENVIGLMDVFTPNSS---LEEF---DDLIRNVASWHVPSCEGSTLPVSVN-----SYIHSAGIIHRDLKPSNLAVNED--CELKILDFGLARHADDE--MTGYVATRWYRAPEIMLN------------WMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSLPYTQKRDFKDVFLGANPLVVDLLERMLVLDTDQRITAAEALVH</Hsp_qseq>
      <Hsp_hseq>VGQGAFATVKKAIERTTGKTFAVKIISKR-KVIGNMDGVTRELEVLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAA-HGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQ-DQLYKQIGRGSYHEGPLKDFRISEEARDFIDSL--------------------------LQVDPNNRSTAAKALNH</Hsp_hseq>
      <Hsp_midline>VG GA+ +V  +++  TG   AVK +S+  + + +     REL +L+ + H  ++ L   +    S   + EF    DL+  VA+ H    E +   +S        YIHS GI HRDLKP N+ + +D    +KI DFGLA+   +   M  +  T  Y APE++                 Y+  VD+WS+GC++  +LTG   F G+   +QL K +         L D   S+EAR++I SL                          L +D + R TAA+AL H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.5893</Hsp_bit-score>
      <Hsp_score>231</Hsp_score>
      <Hsp_evalue>1.35492e-20</Hsp_evalue>
      <Hsp_query-from>531</Hsp_query-from>
      <Hsp_query-to>1130</Hsp_query-to>
      <Hsp_hit-from>1181</Hsp_hit-from>
      <Hsp_hit-to>1400</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>223</Hsp_align-len>
      <Hsp_qseq>VGSGAYGSVCSSLDTKTGMKVAVKKLSRP--------FQSVIHAKRTYRELRLLKHMKHENVIGLMDVFTPNSSLEEF---------DDLIRNVASWHVPSCEGSTLPVSVN-SYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADD-----EMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPP</Hsp_qseq>
      <Hsp_hseq>IGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRS--EVSTLKDLDHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMT-MRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPP</Hsp_hseq>
      <Hsp_midline>+G G++G+V   L+  TG  +AVK++  P          S + A R+  E+  LK + H N++  +     N+    F           LIR    +  P  +  T  V    +Y+HS GI+HRD+K  NL +++D   KI DFG++R + D     +MT    T ++ APE++     Y+  VDIWS+GCI+ E+  G+  +   + +  + KI +    PP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.8853</Hsp_bit-score>
      <Hsp_score>211</Hsp_score>
      <Hsp_evalue>1.04823e-18</Hsp_evalue>
      <Hsp_query-from>522</Hsp_query-from>
      <Hsp_query-to>1292</Hsp_query-to>
      <Hsp_hit-from>73</Hsp_hit-from>
      <Hsp_hit-to>308</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>47</Hsp_gaps>
      <Hsp_align-len>270</Hsp_align-len>
      <Hsp_qseq>LTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKR---TYRELRLLKHMKHENVIGLMDVFTPNSSL---------EEFDDLIRNVASWHVPSCEGSTLPVSVN-SYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSLPYTQKRDFKDVFLGANPLVVDLLERMLVLDTDQRI</Hsp_qseq>
      <Hsp_hseq>MRTLGTGSFGRVHLVRSVHNGRYYAIKVLKK--QQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTPDYIAPEVITT-KPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYF-------------------------------HPDVVDLLSKLITADLTRRI</Hsp_hseq>
      <Hsp_midline>+ ++G+G++G V        G   A+K L +  Q V+  K+   T  E R+LK ++H  +I +   F    ++          E   L+R    +  P  +     V +   Y+H+  II+RDLKP N+ ++ +  +KI DFG A+           T  Y APE++     YN++VD WS+G ++ E+L G T F  T  +    KILQ     P Y                                +P VVDLL +++  D  +RI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.6557</Hsp_bit-score>
      <Hsp_score>213</Hsp_score>
      <Hsp_evalue>1.5576e-18</Hsp_evalue>
      <Hsp_query-from>531</Hsp_query-from>
      <Hsp_query-to>1325</Hsp_query-to>
      <Hsp_hit-from>131</Hsp_hit-from>
      <Hsp_hit-to>391</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>70</Hsp_gaps>
      <Hsp_align-len>298</Hsp_align-len>
      <Hsp_qseq>VGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKR----TYRELRLLKHMKHENVIGLMDVFTPNSSL---------EEFDDLIRNVASWHVPSCE---GSTLPVSVNSYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDEMT----------------GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSLPYTQKRDFKDVFLGANPLVV-DLLERMLVLDTDQRITAAEALVHQYF</Hsp_qseq>
      <Hsp_hseq>LGDGSYSSVVLATARDSGKKYAVKVLSKEY--LIRQKKVKYVTVEKLALQKLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLN-ETCARYYASQIIDAVDS-LHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPE-LLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKI-----QY---------------------------AFTAGFPQIVKDLVKKLLVRDPNDRLTIKQIKAHLFF</Hsp_hseq>
      <Hsp_midline>+G G+Y SV  +    +G K AVK LS+ +  +I  K+    T  +L L K    + +  L   F   +SL          +F  LI+   S +  +C     S +  +V+S +H+ GIIHRD+KP N+ ++++ ++K+ DFG A+   +E +                 +V T  Y +PE +LN  + +   DIW+ GCI+ ++L G+  F   +      K++++     QY                            F    P +V DL++++LV D + R+T  +   H +F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.6557</Hsp_bit-score>
      <Hsp_score>213</Hsp_score>
      <Hsp_evalue>1.70664e-18</Hsp_evalue>
      <Hsp_query-from>528</Hsp_query-from>
      <Hsp_query-to>1337</Hsp_query-to>
      <Hsp_hit-from>26</Hsp_hit-from>
      <Hsp_hit-to>289</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>83</Hsp_identity>
      <Hsp_positive>128</Hsp_positive>
      <Hsp_gaps>54</Hsp_gaps>
      <Hsp_align-len>294</Hsp_align-len>
      <Hsp_qseq>SVGSGAYGSVCSSLDTKTGMKVAVKKLSRPF---------QSVIHAKRTYRELRLLKHMKHENVIGLMDVFTPNSSL------EEFDDLIRNVASWHVPSCEGSTLPVSVN-----SYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLA--RHADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLI--DRMQSKEARNYIQSLPYTQKRDFKDVFLGANPLVVDLLERMLVLDTDQRITAAEALVHQYFAQYH</Hsp_qseq>
      <Hsp_hseq>TLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELF-NLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPF---DEENGNVRDLLLKVQKGQFEMPNDTEISRDAQ--------------------------DLIGKILVVDPRQRIKIRDILSHPLLKKYQ</Hsp_hseq>
      <Hsp_midline>++G G+ G V  +   +TG + AVK +S+              +      RE+ ++K + H NV+ L DV+  N++L       E  +L  N+   H P  E   +          SY H+ GI+HRDLKP NL ++    +KI DFG+A  +   D +     +  Y APEI+    +     D+WS G I+  LLTGR  F   D  N  V+ L L     Q+ +  D   S++A+                          DL+ ++LV+D  QRI   + L H    +Y </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>86.2705</Hsp_bit-score>
      <Hsp_score>212</Hsp_score>
      <Hsp_evalue>2.61444e-18</Hsp_evalue>
      <Hsp_query-from>513</Hsp_query-from>
      <Hsp_query-to>1325</Hsp_query-to>
      <Hsp_hit-from>41</Hsp_hit-from>
      <Hsp_hit-to>313</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>88</Hsp_identity>
      <Hsp_positive>131</Hsp_positive>
      <Hsp_gaps>52</Hsp_gaps>
      <Hsp_align-len>298</Hsp_align-len>
      <Hsp_qseq>YVNLTSVGSGAYGSV----------CSSLDTKTGMKVAVKKLSRPFQSVIHAK--RTYRELRLLKHMKHENVIGLMDVFTPNSS-----LE-----EFDDLIRNVASW-HVPSCEGSTLPVSVNSYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARH---ADDEMTGYVATRWYRAPEIMLNWMHYN-QTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSLPYTQKRDFKDVFLGANPLVVDLLERMLVLDTDQRITAAEALVHQYF</Hsp_qseq>
      <Hsp_hseq>YILGSTLGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRKEVKIYREINALKHLSHPNIVKLEEVLQ-NSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVNEFCSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAG--YLPWDDDPN----------NPEGSDIGRLY-----NYINSTPL----KFPDYIL---PIPRDLLRRMLVSDPKKRINLKQIKKHEWL</Hsp_hseq>
      <Hsp_midline>Y+  +++G G +G V           S+       +VA+K + R   S  + K  + YRE+  LKH+ H N++ L +V   NS      LE     EF   I+       + +C   +  +S   YIHS G++HRDLK  NL ++++  L I DFG        ++ M     +  Y APE++++   Y  +  DIWS G I+  +L G    P  D  N           P    I R+      NYI S P      F D  L   P+  DLL RMLV D  +RI   +   H++ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>84.7297</Hsp_bit-score>
      <Hsp_score>208</Hsp_score>
      <Hsp_evalue>3.99452e-18</Hsp_evalue>
      <Hsp_query-from>507</Hsp_query-from>
      <Hsp_query-to>1070</Hsp_query-to>
      <Hsp_hit-from>35</Hsp_hit-from>
      <Hsp_hit-to>239</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>206</Hsp_align-len>
      <Hsp_qseq>RRYVNLTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPF--QSVIHAKRTYRELRLLKHMKHENVIGLMDVFTPNSSL----------EEFDDLIRNVASWHVPSCEGSTLPVSVNSYIHSAGIIHRDLKPSNLAV---NEDCELKILDFGLARH--ADDEMTGYVA-TRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLF</Hsp_qseq>
      <Hsp_hseq>KKYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGH-GKPCDIWSIGVITYTLLCGYSAF</Hsp_hseq>
      <Hsp_midline>++YV   ++G+G +G V  + +T+TG  VAVK L +     + +  +  Y EL +L+ + H N++   D F                E FD +++        +       +S   Y+HS  I+HRDLKP NL     +++  L + DFG+A+   +D+E+    A +  Y APE++    H  +  DIWS+G I   LL G + F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.1889</Hsp_bit-score>
      <Hsp_score>204</Hsp_score>
      <Hsp_evalue>1.50182e-17</Hsp_evalue>
      <Hsp_query-from>423</Hsp_query-from>
      <Hsp_query-to>1325</Hsp_query-to>
      <Hsp_hit-from>169</Hsp_hit-from>
      <Hsp_hit-to>480</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>92</Hsp_identity>
      <Hsp_positive>138</Hsp_positive>
      <Hsp_gaps>65</Hsp_gaps>
      <Hsp_align-len>339</Hsp_align-len>
      <Hsp_qseq>PHTPTTMSSDVKEGFCRQELNKTV-WEVPRRYVNLTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKRTYRE-LRLLKHMKHENVIGLMDVFTPNSS---------LEEFDD------LIRNVASWHVPSCEGSTLPVSVNSYIHSAGIIHRDLKPSNLAVN-------------------EDCELKILDFGLARHADD-EMTGYV-ATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSLPYTQKRDFKDVFLGANPLVVDLLERMLVLDTDQRITAAEALVHQYF</Hsp_qseq>
      <Hsp_hseq>PQISATSSQNATTSAAIRKLNKTRPVSFFDKYLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEV-LTKKGYTSKVDLWSAGVILYVCLCG--FPPFSDQLG-----------PPSLKEQILQAK----YAFYSPYWDKID---------DSVLHLISNLLVLNPDERYNIDEALNHPWF</Hsp_hseq>
      <Hsp_midline>P    T S +       ++LNKT       +Y+    +G+G Y  V  + + KTG +VAVK             + +RE   +L  ++H N++ L+D F    S         LE+ DD      ++R        S       ++   Y+H   IIHRD+KP N+ +N                    D ++KI DFGLA+   + + T  +  T  Y APE+ L    Y   VD+WS G I+   L G    P +D +            PP      +Q+K    Y    PY  K D           V+ L+  +LVL+ D+R    EAL H +F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.1889</Hsp_bit-score>
      <Hsp_score>204</Hsp_score>
      <Hsp_evalue>1.68733e-17</Hsp_evalue>
      <Hsp_query-from>513</Hsp_query-from>
      <Hsp_query-to>1325</Hsp_query-to>
      <Hsp_hit-from>55</Hsp_hit-from>
      <Hsp_hit-to>306</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>126</Hsp_positive>
      <Hsp_gaps>43</Hsp_gaps>
      <Hsp_align-len>283</Hsp_align-len>
      <Hsp_qseq>YVNLTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAK-RTYRELRLLKHMKHENVIGLMDVFTPNSSL---------EEFDDLIRNVASWHVPSCEGSTLPVSVNSYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDE--MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSLPYTQKRDFKDVFLGANPLVVDLLERMLVLDTDQRITAAEALVHQYF</Hsp_qseq>
      <Hsp_hseq>YQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFD-----DESIPVL---------------FKNISNGVYTLPK---------FL--SPGAAGLIKRMLIVNPLNRISIHEIMQDDWF</Hsp_hseq>
      <Hsp_midline>Y  + ++G G++G V  +  T TG KVA+K +++   +    + R  RE+  L+ ++H ++I L DV      +         E FD +++        +       +S   Y H   I+HRDLKP NL ++E   +KI DFGL+    D   +     +  Y APE++   ++    VD+WS G I+  +L  R  F      ++ + +L                K   N + +LP          FL  +P    L++RML+++   RI+  E +   +F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.1889</Hsp_bit-score>
      <Hsp_score>204</Hsp_score>
      <Hsp_evalue>2.33823e-17</Hsp_evalue>
      <Hsp_query-from>531</Hsp_query-from>
      <Hsp_query-to>1325</Hsp_query-to>
      <Hsp_hit-from>185</Hsp_hit-from>
      <Hsp_hit-to>443</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>131</Hsp_positive>
      <Hsp_gaps>76</Hsp_gaps>
      <Hsp_align-len>300</Hsp_align-len>
      <Hsp_qseq>VGSGAYGSV--CSSLDTKTGMKVAVKKLSRPF-------QSVIHAKRTYREL-------RLLKHMKHENVIGLMDVFTPN----SSLEEFDDLIRNVASWHVPSCEGSTLPVSVNSYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLAR--------------HADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSLPYTQKRDFKDVFLGANPLVV-DLLERMLVLDTDQRITAAEALVHQYF</Hsp_qseq>
      <Hsp_hseq>IGDGAYSTVMLATSIDTK--KRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQI------IDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPE-LLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKV-----QY---------------------------AFTPGFPLIIRDLVKKILVKNLDRRLTISQIKEHHFF</Hsp_hseq>
      <Hsp_midline>+G GAY +V   +S+DTK   + A K L++ +       + V   K   ++L       RL    + E+ +  +  + PN    S ++++  L    A ++          +    Y+HS GIIHRD+KP N+ ++ + ++K+ DFG A+                      +V T  Y +PE +LN    +   DIW+ GCI+ +++ G+  F  T+      K++++     QY                            F    PL++ DL++++LV + D+R+T ++   H +F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.2629</Hsp_bit-score>
      <Hsp_score>199</Hsp_score>
      <Hsp_evalue>5.21541e-17</Hsp_evalue>
      <Hsp_query-from>504</Hsp_query-from>
      <Hsp_query-to>1070</Hsp_query-to>
      <Hsp_hit-from>38</Hsp_hit-from>
      <Hsp_hit-to>249</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>213</Hsp_align-len>
      <Hsp_qseq>PRRYVNLT------SVGSGAYGSVCSSLDTKTGMKVAVK-KLSRPFQ-SVIHAKRTYRELRLLKHMKHENVIGLMDVFTPNSSL----------EEFDDLIRNVASWHVPSCEGSTLPVSVNSYIHSAGIIHRDLKPSNLAV---NEDCELKILDFGLARH---ADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLF</Hsp_qseq>
      <Hsp_hseq>PESYVNRTNYIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGH-GKPCDIWSIGVITYTLLCGYSPF</Hsp_hseq>
      <Hsp_midline>P  YVN T      ++G+G++G V  +    T   VA+K  L +  Q + +  +  Y EL +L+ + H N++   D F                E FD ++       V + E     +    Y+HS  ++HRDLKP N+     +E+  L I DFG+A+     +D +     +  Y APE++    H  +  DIWS+G I   LL G + F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.8777</Hsp_bit-score>
      <Hsp_score>198</Hsp_score>
      <Hsp_evalue>5.25891e-17</Hsp_evalue>
      <Hsp_query-from>522</Hsp_query-from>
      <Hsp_query-to>1109</Hsp_query-to>
      <Hsp_hit-from>91</Hsp_hit-from>
      <Hsp_hit-to>296</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>209</Hsp_align-len>
      <Hsp_qseq>LTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKR---TYRELRLLKHMKHENVIGLMDVFTPNSSL---------EEFDDLIRNVASWHVPSCEGSTLPVSVN-SYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKIL</Hsp_qseq>
      <Hsp_hseq>LRTLGTGSFGRVHLIRSNHNGRFYALKTLKK--HTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEV-VSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENIL</Hsp_hseq>
      <Hsp_midline>L ++G+G++G V        G   A+K L +   +++  K+   T  E R+L  + H  +I +   F  +  +          E   L+R    +  P  +     V +   Y+HS  II+RDLKP N+ ++++  +KI DFG A++  D       T  Y APE+ ++   YN++VD WS G ++ E+L G T F  ++ +     IL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>81.6481</Hsp_bit-score>
      <Hsp_score>200</Hsp_score>
      <Hsp_evalue>7.2549e-17</Hsp_evalue>
      <Hsp_query-from>510</Hsp_query-from>
      <Hsp_query-to>1070</Hsp_query-to>
      <Hsp_hit-from>619</Hsp_hit-from>
      <Hsp_hit-to>814</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>101</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>202</Hsp_align-len>
      <Hsp_qseq>RYVNLTSVGSGAYGSVCSSLDTKTGMKVAVKKLS---RPFQSVIHAKRTYRELRLLKHMKHENVIGLMDVFTPNSSL----EEFDDLIRNVASWHVPSCEGSTLPVSVNS-----YIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADD---EMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLF</Hsp_qseq>
      <Hsp_hseq>KYANLVKIGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKELI-----INEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVTHCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTMVGTPYWMAPEV-VSRKEYGPKVDIWSLGIMIIEMIEGEPPY</Hsp_hseq>
      <Hsp_midline>+Y NL  +G GA G V ++ +  T + VA+K+++   +P + +I       E+ ++K  KH N++  +D +     L    E  +         H    EG    V   +     ++HS G++HRD+K  N+ ++ + ++K+ DFG     ++   + T  V T ++ APE+ ++   Y   VDIWS+G ++ E++ G   +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.4925</Hsp_bit-score>
      <Hsp_score>197</Hsp_score>
      <Hsp_evalue>1.01092e-16</Hsp_evalue>
      <Hsp_query-from>531</Hsp_query-from>
      <Hsp_query-to>1154</Hsp_query-to>
      <Hsp_hit-from>134</Hsp_hit-from>
      <Hsp_hit-to>392</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>53</Hsp_gaps>
      <Hsp_align-len>260</Hsp_align-len>
      <Hsp_qseq>VGSGAYGSVCSSLDTKTGMKVAVKKLSRP----FQSVIHAK-----------------------RTYRELRLLKHMKHENVIGLMDVFTPNSSLEEFDDLIRNVASWHVPSCEGSTLPVSVNSY----------IHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHA------DDE-------MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTP--PQYLIDRMQ</Hsp_qseq>
      <Hsp_hseq>LGQGAYGKVLLVKDVNTSKLYAMKQLRKAEILISQTATDSKREDEDKNDGNNNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLG-KAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIPFYLSEGMK</Hsp_hseq>
      <Hsp_midline>+G GAYG V    D  T    A+K+L +      Q+   +K                       RT+ E  +L  ++H N++ L   F  NS L      I     ++     G+    +V+ Y          +H+ G+++RDLKP N  +N+   L + DFGL++ +      D+E       +   + T  Y APEI+L    Y+Q  D +S+GC++ ++L G+  + G++H   + KI Q    P  P YL + M+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.1073</Hsp_bit-score>
      <Hsp_score>196</Hsp_score>
      <Hsp_evalue>2.42213e-16</Hsp_evalue>
      <Hsp_query-from>528</Hsp_query-from>
      <Hsp_query-to>1334</Hsp_query-to>
      <Hsp_hit-from>24</Hsp_hit-from>
      <Hsp_hit-to>292</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>128</Hsp_positive>
      <Hsp_gaps>62</Hsp_gaps>
      <Hsp_align-len>300</Hsp_align-len>
      <Hsp_qseq>SVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKRTY---------------RELRLLKHMKHENVIGLMDVFTPNSSL----------EEFDDLIRNVASWHVPSCEG----STLPVSVNSYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDE--MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSLPYTQKRDFKDVFLGANPLVVDLLERMLVLDTDQRITAAEALVHQYFAQY</Hsp_qseq>
      <Hsp_hseq>TLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLL---VERGPLPEHEAIRFFRQIIIGV-SYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDG-NIRTLLLKVQKGEFEMPSDDEISREAQ--------------------------DLIRKILTVDPERRIKTRDILKHPLLQKY</Hsp_hseq>
      <Hsp_midline>++G G+ G V  + +  TG + AVK +S+   +  +   T                RE+ ++K + H NV+ L DV+  N+ L          E F+ L   V    +P  E       + + V SY H+ GI+HRDLKP NL ++    +KI DFG+A    +   +     +  Y APEI+    +     D+WS G I+  LLTGR  F   D  N    +L++     +   D   S+EA+                          DL+ ++L +D ++RI   + L H    +Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.7221</Hsp_bit-score>
      <Hsp_score>195</Hsp_score>
      <Hsp_evalue>3.93606e-16</Hsp_evalue>
      <Hsp_query-from>651</Hsp_query-from>
      <Hsp_query-to>1334</Hsp_query-to>
      <Hsp_hit-from>163</Hsp_hit-from>
      <Hsp_hit-to>372</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>244</Hsp_align-len>
      <Hsp_qseq>RELRLLKHMKHENVIGLMDVFTPNSSL----------EEFDDLIRNVASWHVPSCEG---STLPVSVNSYIHSAGIIHRDLKPSNLAVNE-DCELKILDFGLA--RHADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSLPYTQKRDFKDVFLGANPLVVDLLERMLVLDTDQRITAAEALVHQYFAQY</Hsp_qseq>
      <Hsp_hseq>REIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYL---VSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPF-NDDNIKKLLLKVQ-SG---KYQMPSNLSSEAR--------------------------DLISKILVIDPEKRITTQEILKHPLIKKY</Hsp_hseq>
      <Hsp_midline>RE+ ++K + H NV+ L +V+   S L          E FD L   V+   +P  E        V   SY HS  I HRDLKP NL +++ +  +KI DFG+A     +  +     +  Y +PEI++   ++    D+WS G ++  LLTG   F   D+I +L+  +Q +G   +Y +    S EAR                          DL+ ++LV+D ++RIT  E L H    +Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.5666</Hsp_bit-score>
      <Hsp_score>192</Hsp_score>
      <Hsp_evalue>4.96196e-16</Hsp_evalue>
      <Hsp_query-from>531</Hsp_query-from>
      <Hsp_query-to>1115</Hsp_query-to>
      <Hsp_hit-from>220</Hsp_hit-from>
      <Hsp_hit-to>429</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>215</Hsp_align-len>
      <Hsp_qseq>VGSGAYGSVCSSLDTKTGMKV-AVKKLSRPFQSVIHAKRTYRELRLLKHMKHENVIGLMDVFTP--------------NSSLEE-FDDLIRN---VASWHVPSCEGSTLPVSVNSYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDEMT-GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQL</Hsp_qseq>
      <Hsp_hseq>LGEGAGGSV-AKCRLKNGKKVFALKTINTMNTDPEYQKQIFRELQFNKSFKSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVL--RGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFGVSGEAVNSLAMTFTGTSFYMAPE-RIQGQPYSVTCDVWSLGLTLLEVAGGRFPFE-SDKITQNVAPIEL</Hsp_hseq>
      <Hsp_midline>+G GA GSV +    K G KV A+K ++       + K+ +REL+  K  K + ++    +FT                 SLE  + +L++    ++   +     S L     SY+H   +IHRD+KP N+ +NE  E+K+ DFG++  A + +   +  T +Y APE  +    Y+ T D+WS+G  + E+  GR  F  +D I Q V  ++L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YLL019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:105686:107899:-1 gene:YLL019C transcript:YLL019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KNS1 description:Protein kinase involved in negative regulation of PolIII transcription; effector kinase of the TOR signaling pathway and phosphorylates Rpc53p to regulate ribosome and tRNA biosynthesis; member of the LAMMER family of protein kinases, which are serine/threonine kinases also capable of phosphorylating tyrosine residues; capable of autophosphorylation [Source:SGD;Acc:S000003942]</Hit_def>
  <Hit_accession>YLL019C</Hit_accession>
  <Hit_len>737</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.5666</Hsp_bit-score>
      <Hsp_score>192</Hsp_score>
      <Hsp_evalue>6.30387e-16</Hsp_evalue>
      <Hsp_query-from>510</Hsp_query-from>
      <Hsp_query-to>1151</Hsp_query-to>
      <Hsp_hit-from>312</Hsp_hit-from>
      <Hsp_hit-to>572</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>114</Hsp_positive>
      <Hsp_gaps>53</Hsp_gaps>
      <Hsp_align-len>264</Hsp_align-len>
      <Hsp_qseq>RYVNLTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKRTYRELRLLKHMKHENVIG------LMDVFTPNSSLEEFDDLIRN-----VASWHVPSCEGSTLPVSVNS------YIHSAGIIHRDLKPSNLAVNEDC--------------------------------ELKILDFGLARHADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTP-PQYLIDRM</Hsp_qseq>
      <Hsp_hseq>RFVVKDLLGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDRYREAAKT--ELRILQTILNNDPQGQFQCLLLRECFDYKNHICLVTDLYGRSIYDFMCSNGIARFPGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENILICDETHIAQKLPLKTVQSLSKRRREASKGKRKILKNPEIKIIDFGSAIFHYEYHPPVISTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVIGESLYPIHENLEHMAMMQRINGTPFPTDIIDKM</Hsp_hseq>
      <Hsp_midline>R+V    +G G +G V   +D K        K+ R       A +T  ELR+L+ + + +  G      L + F   + +    DL        + S  +    GS +            ++H  GIIH DLKP N+ + ++                                 E+KI+DFG A    +     ++TR YRAPEI+L  + ++   DIWS+ C++ EL+ G +L+P  +++  +  + ++ GTP P  +ID+M</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.1814</Hsp_bit-score>
      <Hsp_score>191</Hsp_score>
      <Hsp_evalue>6.62341e-16</Hsp_evalue>
      <Hsp_query-from>522</Hsp_query-from>
      <Hsp_query-to>1070</Hsp_query-to>
      <Hsp_hit-from>53</Hsp_hit-from>
      <Hsp_hit-to>276</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>41</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>LTSVGSGAYGSVCSSLDTKTGMKVAVKKLSR-------PFQSVIHAKRTYRELRLLKHMKHENVIGLMDVFTPNSSLEEF---DDLIRNVASW------HVPSCEGSTLP-----------VSVNSYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDEMTGY------------VATRWYRAPEIMLNWMHY--NQTVDIWSVGCIMAELLTGRTLF</Hsp_qseq>
      <Hsp_hseq>LATLGNGQYGKVKLARDLGTGALVAIKILNRFEKRSGYSLQLKVENPRVNQEIEVMKRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPF</Hsp_hseq>
      <Hsp_midline>L ++G+G YG V  + D  TG  VA+K L+R         Q  +   R  +E+ ++K   HENV+ L ++     S + +   +   R    W       + +   S L            VS   Y+HS GI HRD+KPSNL ++ +  +KI DFG+A       T              + T  + APE+      Y  +  +DIWS+G  +  LL G+  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.6406</Hsp_bit-score>
      <Hsp_score>187</Hsp_score>
      <Hsp_evalue>1.04388e-15</Hsp_evalue>
      <Hsp_query-from>522</Hsp_query-from>
      <Hsp_query-to>1109</Hsp_query-to>
      <Hsp_hit-from>90</Hsp_hit-from>
      <Hsp_hit-to>295</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>209</Hsp_align-len>
      <Hsp_qseq>LTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKR---TYRELRLLKHMKHENVIGLMDVFTPNSSL---------EEFDDLIRNVASWHVPSCEGSTLPVSVN-SYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKIL</Hsp_qseq>
      <Hsp_hseq>LRTLGTGSFGRVHLIRSRHNGRYYAMKVLKK--EIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEV-VSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKIL</Hsp_hseq>
      <Hsp_midline>L ++G+G++G V        G   A+K L +  + V+  K+   T  E  +L  + H  +I +   F     +          E   L+R    +  P  +     V +   Y+HS  II+RDLKP N+ ++++  +KI DFG A++  D       T  Y APE+ ++   YN+++D WS G ++ E+L G T F  ++ +    KIL</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>77.7962</Hsp_bit-score>
      <Hsp_score>190</Hsp_score>
      <Hsp_evalue>1.35881e-15</Hsp_evalue>
      <Hsp_query-from>816</Hsp_query-from>
      <Hsp_query-to>1154</Hsp_query-to>
      <Hsp_hit-from>824</Hsp_hit-from>
      <Hsp_hit-to>952</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>73</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>134</Hsp_align-len>
      <Hsp_qseq>SYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARH-----------------ADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFP---GTDHINQLVKILQLT-GTPPQYLIDRMQ</Hsp_qseq>
      <Hsp_hseq>SYIHSQGIIHRDLKPMNIFIDESRNVKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVLDGTGHYNEKIDMYSLGIIFFEM-----IYPFSTGMERVNILKKLRSVSIEFPPDFDDNKMK</Hsp_hseq>
      <Hsp_midline>SYIHS GIIHRDLKP N+ ++E   +KI DFGLA++                 + D +T  + T  Y A E++    HYN+ +D++S+G I  E+     ++P   G + +N L K+  ++   PP +  ++M+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.2554</Hsp_bit-score>
      <Hsp_score>186</Hsp_score>
      <Hsp_evalue>2.08939e-15</Hsp_evalue>
      <Hsp_query-from>477</Hsp_query-from>
      <Hsp_query-to>1073</Hsp_query-to>
      <Hsp_hit-from>206</Hsp_hit-from>
      <Hsp_hit-to>421</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>220</Hsp_align-len>
      <Hsp_qseq>ELNKTVWE---VPRRYVNLTSVGSGAYGSVCSSLDTKTGMKV-AVKKLSRPFQSVIHAKRTYRELRLLKHMKHENVIGLMDVFT--PNSSL---------EEFDDLIRNVASWHVPSCEGSTLPVSVN-----SYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDEM-TGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFP</Hsp_qseq>
      <Hsp_hseq>QLDENGWKYANLKDRIETLGILGEGAGGSV-SKCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQFNRSFQSEYIVRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVSGEAVNSLATTFTGTSFYMAPE-RIQGQPYSVTSDVWSLGLTILEVANGK--FP</Hsp_hseq>
      <Hsp_midline>+L++  W+   +  R   L  +G GA GSV S    K G K+ A+K ++       + K+ +REL+  +  + E ++    +FT   NSS+            D + +N+        E     ++       SY+H   +IHRD+KP N+ +NE+ ++K+ DFG++  A + + T +  T +Y APE  +    Y+ T D+WS+G  + E+  G+  FP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.1738</Hsp_bit-score>
      <Hsp_score>178</Hsp_score>
      <Hsp_evalue>2.95356e-14</Hsp_evalue>
      <Hsp_query-from>504</Hsp_query-from>
      <Hsp_query-to>1181</Hsp_query-to>
      <Hsp_hit-from>412</Hsp_hit-from>
      <Hsp_hit-to>690</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>63</Hsp_gaps>
      <Hsp_align-len>284</Hsp_align-len>
      <Hsp_qseq>PRRYVNLTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSV---------------------------------------IHAKRT---YRELRLLKHMKHENVI---------GLMDVFTPNSSLEEFDDLIRNVASWHVPSCEGSTLPVSVN-SYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLAR------HADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQ</Hsp_qseq>
      <Hsp_hseq>PKNWLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEV-VKQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKI--GTNTTPE--IPSWATSEGKNFLR</Hsp_hseq>
      <Hsp_midline>P+ ++    +GSG++GSV   ++  TG  +AVK++     ++                                       IH K       E+ LLK + HEN++         G +++F           ++ N   +        T  + +  +Y+H   IIHRD+K +N+ ++    +KI DFG+++         ++      + ++ +PE+ +         DIWS GC++ E+ TG+  FP    +  + KI   T T P+  I    + E +N+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>71.633</Hsp_bit-score>
      <Hsp_score>174</Hsp_score>
      <Hsp_evalue>8.45833e-14</Hsp_evalue>
      <Hsp_query-from>531</Hsp_query-from>
      <Hsp_query-to>1082</Hsp_query-to>
      <Hsp_hit-from>88</Hsp_hit-from>
      <Hsp_hit-to>285</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>203</Hsp_align-len>
      <Hsp_qseq>VGSGAYGSVCSSLDTKTGMKVAVKKLSRP-FQSVIHAKRTYRELRLLKHMKHENVIGLMDVF------------TPNSSLEEFDDLIRNVASWHVPSCEGSTLPV-SVNSYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLAR-HADDEMTGYV--ATRWYRAPEIMLNWMHYNQT--VDIWSVGCIMAELLTGRTLFPGTD</Hsp_qseq>
      <Hsp_hseq>LGEGGFAR-CFQIKDDSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLME---LLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMG-KHSGHSFEVDIWSLGVMLYALLIGKPPFQARD</Hsp_hseq>
      <Hsp_midline>+G G +   C  +   +G   A K +++   +S    K+   E+++ K M H N++  +D F             PN SL E   L++       P     T  +     Y+HS  +IHRDLK  N+  + +  LKI DFGLA   A++    Y    T  Y APE+++   H   +  VDIWS+G ++  LL G+  F   D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.8626</Hsp_bit-score>
      <Hsp_score>172</Hsp_score>
      <Hsp_evalue>1.95934e-13</Hsp_evalue>
      <Hsp_query-from>513</Hsp_query-from>
      <Hsp_query-to>1139</Hsp_query-to>
      <Hsp_hit-from>46</Hsp_hit-from>
      <Hsp_hit-to>282</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>239</Hsp_align-len>
      <Hsp_qseq>YVNLTSVGSGAYGSVC-----SSLDTKTGMKVAVKKLSRPF--QSVIHAKRTYRELRLLKHMKHENVIGLMDVFTPN----------SSLEEFDDLIRNVASWHVPSCEGSTLPVSVNSYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARH--ADDE-MTGYVATRWYRAPEIMLNWMHYN-QTVDIWSVGCIMAELLTGRTLF------PGTDHINQLVKILQLTGTP---PQYL</Hsp_qseq>
      <Hsp_hseq>YIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARLYKY--ITQTPLKFPEYI</Hsp_hseq>
      <Hsp_midline>Y+  +++G G +G V      +S   +   +VA+K + R    +      + YRE+  LKH+ H N+I L +V   +          S  E +  + R        +C      +S  +Y+H  G++HRDLK  NL +++   L I DFG       D+E M     +  Y APE++++   Y  +  D+WS G I+  +L G   +      P  D I +L K   +T TP   P+Y+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YOR267C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:822588:824867:-1 gene:YOR267C transcript:YOR267C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRK1 description:Protein kinase; implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005793]</Hit_def>
  <Hit_accession>YOR267C</Hit_accession>
  <Hit_len>759</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>2.77988e-13</Hsp_evalue>
      <Hsp_query-from>531</Hsp_query-from>
      <Hsp_query-to>1073</Hsp_query-to>
      <Hsp_hit-from>221</Hsp_hit-from>
      <Hsp_hit-to>420</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>100</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>203</Hsp_align-len>
      <Hsp_qseq>VGSGAYGSVCSSLDTKTGMKVAVKKLS--RPFQSVI-HAKRTYRELRLLKHMKHENVIGLMDVFTPNSSLEEFD-------DLIRNVASWHVP----SCEGSTLPVSVNSYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLA---RHA-DDEMT---GYVATRWYRAPEIMLNWMHYN-QTVDIWSVGCIMAELLTGRTLFP</Hsp_qseq>
      <Hsp_hseq>LGSGAGGSVKVLVRPTDGATFAVKEFRPRKPNESVKEYAKKCTAEFCIGSTLHHPNVIETVDVFSDSKQNKYYEVMEYCPIDFFAVVMTGKMSRGEINCCLKQLTEGV-KYLHSMGLAHRDLKLDNCVMTSQGILKLIDFGSAVVFRYPFEDGVTMAHGIVGSDPYLAPEVITSTKSYDPQCVDIWSIGIIYCCMVLKR--FP</Hsp_hseq>
      <Hsp_midline>+GSGA GSV   +    G   AVK+    +P +SV  +AK+   E  +   + H NVI  +DVF+ +   + ++       D    V +  +     +C    L   V  Y+HS G+ HRDLK  N  +     LK++DFG A   R+  +D +T   G V +  Y APE++ +   Y+ Q VDIWS+G I   ++  R  FP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.707</Hsp_bit-score>
      <Hsp_score>169</Hsp_score>
      <Hsp_evalue>3.00244e-13</Hsp_evalue>
      <Hsp_query-from>516</Hsp_query-from>
      <Hsp_query-to>1208</Hsp_query-to>
      <Hsp_hit-from>192</Hsp_hit-from>
      <Hsp_hit-to>453</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>121</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>263</Hsp_align-len>
      <Hsp_qseq>VNLTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKRTYRELRLLKHMK-HENVIGLMDVF---------------TPNSSLEEFDDLIRNVASWHVPSCEGS---TLPVSVNSYIHSAG---------IIHRDLKPSNLAVNEDCELKILDFGLARHADDEMTG-YVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPG-TDHINQLVKILQ-LTGTP-PQYLIDRMQSKEARNYIQSLPYTQKRD</Hsp_qseq>
      <Hsp_hseq>VQLGKIGAGNSGTVVKALHVPDSKIVAKKTIPVEQNNSTIINQLVRELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKLINSIADTFVGTSTYMSPERIQGNV-YSIKGDVWSLGLMIIELVTGEFPLGGHNDTPDGILDLLQRIVNEPSPRLPKDRIYSKEMTDFVNRCCIKNERE</Hsp_hseq>
      <Hsp_midline>V L  +G+G  G+V  +L       VA K +     +     +  REL ++K++K HEN+I     +               +   SL++   + +        S + +    L +S  +Y    G         IIHRD+KPSN+ +N   ++K+ DFG+++   + +   +V T  Y +PE +   + Y+   D+WS+G ++ EL+TG     G  D  + ++ +LQ +   P P+   DR+ SKE  +++       +R+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>69.3218</Hsp_bit-score>
      <Hsp_score>168</Hsp_score>
      <Hsp_evalue>5.3735e-13</Hsp_evalue>
      <Hsp_query-from>435</Hsp_query-from>
      <Hsp_query-to>1178</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>253</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>114</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>272</Hsp_align-len>
      <Hsp_qseq>TTMSSDVKEGFCRQELNKTVWEVPRRYVNLTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKRTYRELRLLKHMKHENVIGLMDVFTPNSSLEEFDDLIRNVASWHV-PSCEGSTL-----PVSVNSY---------------IHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADD---EMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYI</Hsp_qseq>
      <Hsp_hseq>TTKPQNSKQGLAEGEM-----DVSSLFKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSD-EVEDVQREIQFLASLKQISNI-----------TRYYGSYLKDTSLWIIMEHCAGGSLRSLLRPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIK---SKPPRLEDRSYSTSLKEFI</Hsp_hseq>
      <Hsp_midline>TT   + K+G    E+     +V   +     +G G +G V    + KTG   A+K L+    S    +   RE++ L  +K  + I              +   +++ + W +   C G +L     P  ++                 IH   +IHRD+K +N+ +  +  +K+ DFG+A   +           T ++ APE+++  ++Y+  VDIWS+G    E+ TG   +   + +  +  I++   + P  L DR  S   + +I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>8.05749e-13</Hsp_evalue>
      <Hsp_query-from>450</Hsp_query-from>
      <Hsp_query-to>1244</Hsp_query-to>
      <Hsp_hit-from>3</Hsp_hit-from>
      <Hsp_hit-to>325</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>130</Hsp_positive>
      <Hsp_gaps>70</Hsp_gaps>
      <Hsp_align-len>329</Hsp_align-len>
      <Hsp_qseq>DVKEGFCRQELNKTVWEVPRRYVNLTSVGSGAYGSVCSS-LDTKTGMKVAVKKLSRPFQSVIHAKRTYR----ELRLLKHMKHENVIGLMD----------------------VFTPNSSLEEFDDLIRNVASWHVPSCEG----------STLP--VSVNSYIHSAGIIHRDLKPSNLAVN------EDCE---------------LKILDFGLARHADDEMTG--YVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTG--TPPQYLIDRMQSKEARNYIQSLPYTQKRDFKDVFLGANPLV</Hsp_qseq>
      <Hsp_hseq>DIKNKDHTTSVNHNLMASAGNYTAEKEIGKGSFATVYRGHLTSDKSQHVAIKEVSR---AKLKNKKLLENLEIEIAILKKIKHPHIVGLIDCERTSTDFYLIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEI-LNYQKYNAKADLWSVGTVVFEMCCGTPPFRASNHLELFKKIKRANDVITFPSYCNIEPELKELICSLLTFDPAQRIGFEEFF--ANKVV</Hsp_hseq>
      <Hsp_midline>D+K       +N  +      Y     +G G++ +V    L +     VA+K++SR   + +  K+       E+ +LK +KH +++GL+D                      +      L E   L+R V   + P  E           S L    S   ++ S  ++HRD+KP NL ++       D +               LKI DFG AR   +         +  Y APEI LN+  YN   D+WSVG ++ E+  G   F  ++H+    KI +     T P Y     + KE    + +    Q+  F++ F  AN +V</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>1.38263e-12</Hsp_evalue>
      <Hsp_query-from>819</Hsp_query-from>
      <Hsp_query-to>1331</Hsp_query-to>
      <Hsp_hit-from>259</Hsp_hit-from>
      <Hsp_hit-to>400</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>176</Hsp_align-len>
      <Hsp_qseq>YIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADD--EMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLV---KILQLTGTPPQYLIDRMQSKEARNYIQSLPYTQKRDFKDVFLGANPLVVDLLERMLVLDTDQRITAAEALVHQYFAQ</Hsp_qseq>
      <Hsp_hseq>YLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPF---DDENSSVLHEKIKQGKVEYPQHL-----SIE--------------------------VISLLSKMLVVDPKRRATLKQVVEHHWMVR</Hsp_hseq>
      <Hsp_midline>Y+H+  I+HRDLK  N+ +++  E+KI+DFGL+   D   ++  +  + ++ APE++    +    VD+WS G ++  L+ G+  F   D  N  V   KI Q     PQ+L     S E                          V+ LL +MLV+D  +R T  + + H +  +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.1662</Hsp_bit-score>
      <Hsp_score>165</Hsp_score>
      <Hsp_evalue>1.72096e-12</Hsp_evalue>
      <Hsp_query-from>480</Hsp_query-from>
      <Hsp_query-to>1085</Hsp_query-to>
      <Hsp_hit-from>1255</Hsp_hit-from>
      <Hsp_hit-to>1505</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>75</Hsp_gaps>
      <Hsp_align-len>264</Hsp_align-len>
      <Hsp_qseq>LNKTVWEVPRRYVNLTSVGSGAYGSVCSSLDTKTGMKVAVKKL----SRPFQSVIHAKRTYRELRLLKHMKHENVIGLMDVFTPNSSLEEFDDLIRNVASWHVPSCEGSTLPVSVN---------------------SYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLAR----------------HADDE-------------------MTGYVATRWYRAPEIMLNWMHYNQ--TVDIWSVGCIMAELLTGRTLFPGTDH</Hsp_qseq>
      <Hsp_hseq>LASSISNVSMRWQKRNFIGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIK--EEMSVLEILNHPNIVSYYGV-----------EVHRDKVNIFMEYCEGGSLAALLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPWANLDN</Hsp_hseq>
      <Hsp_midline>L  ++  V  R+     +G G +G V S++D   G  +AVK++    S+  Q +    +   E+ +L+ + H N++    V           ++ R+  +  +  CEG +L   +                      +Y+H +GI+HRD+KP N+ ++ +  +K +DFG A+                +AD E                   +   + T  Y APE +       +    D+WS+GC++ E++TGR  +   D+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>3.09878e-12</Hsp_evalue>
      <Hsp_query-from>531</Hsp_query-from>
      <Hsp_query-to>1187</Hsp_query-to>
      <Hsp_hit-from>31</Hsp_hit-from>
      <Hsp_hit-to>257</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>106</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>234</Hsp_align-len>
      <Hsp_qseq>VGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKRTYRELRLLKHMKHENVIG------------LMDVFTPNSSLEEFDDLIRNVASWHVPSCEGSTLPVSVN---SYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSL</Hsp_qseq>
      <Hsp_hseq>IGRGSYGVVYKAINKHTDQVVAIKEVV--YENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRR----LISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSALTLAGTLNWMAPEILGN-RGASTLSDIWSLGATVVEMLTKNPPYHNLTDANIYYAVENDTYYPPSSFSEPLKDFLSKCFVKNM</Hsp_hseq>
      <Hsp_midline>+G G+YG V  +++  T   VA+K++   +++         E+ LLK++ H N++             ++  +  N SL      + + +S  +   E  T          Y+H  G+IHRD+K +N+ ++ D  +K+ DFG++   +        T  + APEI+ N    +   DIWS+G  + E+LT    +      N    +   T  PP    + ++   ++ +++++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>3.58078e-12</Hsp_evalue>
      <Hsp_query-from>819</Hsp_query-from>
      <Hsp_query-to>1187</Hsp_query-to>
      <Hsp_hit-from>528</Hsp_hit-from>
      <Hsp_hit-to>647</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>37</Hsp_identity>
      <Hsp_positive>69</Hsp_positive>
      <Hsp_gaps>7</Hsp_gaps>
      <Hsp_align-len>125</Hsp_align-len>
      <Hsp_qseq>YIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHAD--DEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSL</Hsp_qseq>
      <Hsp_hseq>HLHDNDIVYRDLKPENILLDANGNIALCDFGLSK-ADLKDRTNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVL----SQEGRSFVKGL</Hsp_hseq>
      <Hsp_midline>++H   I++RDLKP N+ ++ +  + + DFGL++ AD  D    +  T  Y APE++L+   Y + VD WS+G ++ E+  G + F   ++     KI       P+ ++    S+E R++++ L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>3.89005e-12</Hsp_evalue>
      <Hsp_query-from>501</Hsp_query-from>
      <Hsp_query-to>1331</Hsp_query-to>
      <Hsp_hit-from>1030</Hsp_hit-from>
      <Hsp_hit-to>1312</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>102</Hsp_gaps>
      <Hsp_align-len>331</Hsp_align-len>
      <Hsp_qseq>VPRRYVNLTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKRTYR--------ELRLLKHMKHENVIGLMDVFTPNSSLEEFDDLIRNVASWHVPSCEGSTLPVSVN---------------------SYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLAR----------------------HADDEMTGYVATRWYRAPEIMLNWMHYNQ--TVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQL-TGTPPQYLIDRMQSKEARNYIQSLPYTQKRDFKDVFLGANPLVVDLLERMLVLDTDQRITAAEALVHQYFAQ</Hsp_qseq>
      <Hsp_hseq>VSMRWQKRSFIGGGTFGQVYSAINLENGEILAVKEIK------IHDTTTMKKIFPLIKEEMTVLEMLNHPNIVQYYGV-----------EVHRDKVNIFMEYCEGGSLASLLDHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMG---TPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRR--PWSNLDNEWAIMYHVAAGRIPQ-LPNRDEMTAA-----------GRAF--------------LERCLVQDPTMRATAVELLIDPWMIQ</Hsp_hseq>
      <Hsp_midline>V  R+   + +G G +G V S+++ + G  +AVK++       IH   T +        E+ +L+ + H N++    V           ++ R+  +  +  CEG +L   ++                     +Y+H +G++HRD+KP N+ ++ +  +K +DFG AR                       + +EM G   T  Y APE +       +    D+W++GC++ E+ TGR   P ++  N+   +  +  G  PQ L +R +   A            R F              LER LV D   R TA E L+  +  Q</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YDL025C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:405344:407206:-1 gene:YDL025C transcript:YDL025C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RTK1 description:Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002183]</Hit_def>
  <Hit_accession>YDL025C</Hit_accession>
  <Hit_len>620</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>5.52492e-12</Hsp_evalue>
      <Hsp_query-from>531</Hsp_query-from>
      <Hsp_query-to>1073</Hsp_query-to>
      <Hsp_hit-from>308</Hsp_hit-from>
      <Hsp_hit-to>509</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>206</Hsp_align-len>
      <Hsp_qseq>VGSGAYGSVCSSLDTKTGMKVAVKKLSRPF---------QSVIHAKRTYRELRLLKHMKHENVIGLMDVFTPNSSL---------EEFDDLIRNVASWHVPSCEGSTLPVSVNSYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLA----RHADDEMT---GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFP</Hsp_qseq>
      <Hsp_hseq>LGEGASGSV-SVVERTDGKLFACKMFRKPHLNNEGTNQSQLANYSKKVTTEFCIGSTLHHENIVETLDMLTEGDTYLLVMEYAPYDFFNLVMSNLMTQDEVNCYFKQLCHGVN-YLHSMGLAHRDLKLDNCVVTKDGILKLIDFGSAVVFQYPYEDTIVKSHGIVGSDPYLAPELLKQTSYDPRVADVWSIAIIFYCMVLKR--FP</Hsp_hseq>
      <Hsp_midline>+G GA GSV S ++   G   A K   +P          Q   ++K+   E  +   + HEN++  +D+ T   +          + F+ ++ N+ +    +C    L   VN Y+HS G+ HRDLK  N  V +D  LK++DFG A       +D +    G V +  Y APE++    +  +  D+WS+  I   ++  R  FP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>6.23897e-12</Hsp_evalue>
      <Hsp_query-from>531</Hsp_query-from>
      <Hsp_query-to>1187</Hsp_query-to>
      <Hsp_hit-from>322</Hsp_hit-from>
      <Hsp_hit-to>570</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>110</Hsp_positive>
      <Hsp_gaps>50</Hsp_gaps>
      <Hsp_align-len>259</Hsp_align-len>
      <Hsp_qseq>VGSGAYGSV--C-----SSLDTKTGMKV-AVKKLSRPFQSVI--HAKRTYRELRLLKHMKHENVIGLMDVFTPNSSLEEFDDLIRNVASWHVPSCEGSTLPVSVNS------------------YIHSAGIIHRDLKPSNLAVNEDCELKILDFG------LARHADDEMTGYV-ATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTD-----HINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSL</Hsp_qseq>
      <Hsp_hseq>LGKGAFGVVRICQKKNVSSQDGNKSEKLYAVKEFKRRTSESAEKYSKRLTSEFCISSSLHHTNIVTTLDLF--QDAKGEYCEVMEYCAGGDL-----FTLVVAAGKLEYMEADCFFKQLIRGVVYMHEMGVCHRDLKPENLLLTHDGVLKITDFGNSECFKMAWEKNIHLSGGVCGSSPYIAPEEYIKEEFDPRPVDIWACGVIYMAMRTGRQLWSSAEKDDPFYMNYLKGRKEKGGYEP---IESLKRARCRNVIYSM</Hsp_hseq>
      <Hsp_midline>+G GA+G V  C     SS D     K+ AVK+  R        ++KR   E  +   + H N++  +D+F    +  E+ +++   A   +      TL V+                     Y+H  G+ HRDLKP NL +  D  LKI DFG      +A   +  ++G V  +  Y APE  +      + VDIW+ G I   + TGR L+   +     ++N L    +  G  P   I+ ++    RN I S+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>7.09504e-12</Hsp_evalue>
      <Hsp_query-from>513</Hsp_query-from>
      <Hsp_query-to>1070</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>222</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>92</Hsp_positive>
      <Hsp_gaps>35</Hsp_gaps>
      <Hsp_align-len>221</Hsp_align-len>
      <Hsp_qseq>YVNLTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKRTYRELRLLKHMK-HENVIGLMDVFTPNS------------SLEEFDDLIRNVASWHVPSCEGSTLP------VSVNSYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDEMTGYVATRWYRAPEIMLNWMH---------------YNQ-TVDIWSVGCIMAELLTGRTLF</Hsp_qseq>
      <Hsp_hseq>YTKLRSIQSGTFSTVYKAWSTTHNRYVALKITPKYKTSEANMKNEYDVMKILSSCNPHPNICSMLDFYTDDSYYIMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQIDMQKIIKQLCSAISFAHSLGIAHRDIKPENILLTINGDIKLADWGHAIQSPKSNDFQIGTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFGDCLF</Hsp_hseq>
      <Hsp_midline>Y  L S+ SG + +V  +  T     VA+K   +   S  + K  Y  +++L     H N+  ++D +T +S             L +F D+ ++  S   PS     +        S  S+ HS GI HRD+KP N+ +  + ++K+ D+G A  +       + T  YRAPE     +                YN    D WS+G  +  L+ G  LF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>7.19066e-12</Hsp_evalue>
      <Hsp_query-from>819</Hsp_query-from>
      <Hsp_query-to>1070</Hsp_query-to>
      <Hsp_hit-from>238</Hsp_hit-from>
      <Hsp_hit-to>323</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>51</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>86</Hsp_align-len>
      <Hsp_qseq>YIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHAD--DEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLF</Hsp_qseq>
      <Hsp_hseq>YLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPF</Hsp_hseq>
      <Hsp_midline>Y+H+  I+HRDLK  N+ ++   E+KI+DFGL+   D   ++  +  + ++ APE++    +    VDIWS G ++  L+ G+  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.0846</Hsp_bit-score>
      <Hsp_score>157</Hsp_score>
      <Hsp_evalue>1.22878e-11</Hsp_evalue>
      <Hsp_query-from>513</Hsp_query-from>
      <Hsp_query-to>1088</Hsp_query-to>
      <Hsp_hit-from>1096</Hsp_hit-from>
      <Hsp_hit-to>1310</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>94</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>220</Hsp_align-len>
      <Hsp_qseq>YVNLTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKRTYRELRL------------LKHMKHENVIGLMDVF---------TP----NSSLEEFD--DLIRNVASWHVPSCEGSTLPVSVNSYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADD-EMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHI</Hsp_qseq>
      <Hsp_hseq>FVSLQKMGEGAYGKVNLCIHKKNRYIVVIKMI---FKERILVDTWVRDRKLGTIPSEIQIMATLNKKPHENILRLLDFFEDDDYYYIETPVHGETGCIDLFDLIEFKTNMTEFEAKLIFKQV--VAGIKHLHDQGIVHRDIKDENVIVDSKGFVKIIDFGSAAYVKSGPFDVFVGTIDYAAPEVLGGNPYEGQPQDIWAIGILLYTVVFKENPFYNIDEI</Hsp_hseq>
      <Hsp_midline>+V+L  +G GAYG V   +  K    V +K +   F+  I      R+ +L            L    HEN++ L+D F         TP       ++ FD  +   N+  +           V+   ++H  GI+HRD+K  N+ V+    +KI+DFG A +        +V T  Y APE++    +  Q  DIW++G ++  ++     F   D I</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>2.06409e-11</Hsp_evalue>
      <Hsp_query-from>582</Hsp_query-from>
      <Hsp_query-to>1127</Hsp_query-to>
      <Hsp_hit-from>588</Hsp_hit-from>
      <Hsp_hit-to>786</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>213</Hsp_align-len>
      <Hsp_qseq>GMKVAVKKL---SRPFQSVIHAKRTYRELRLLKHMKHENVIGLMDVFTPNSS----LEEF------DDLIRNVAS---WHVP------------SCEGSTLPVSVNSYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDEMTG---YVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTP</Hsp_qseq>
      <Hsp_hseq>GDKVAIKQMVLSKQPRKELI-----VNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGL-------KFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEV-VKQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALY-LIATNGTP</Hsp_hseq>
      <Hsp_midline>G KVA+K++    +P + +I       E+ ++K  +H+N++  ++ +         + EF       D+I N  +    H P            +C+G         ++H   IIHRD+K  N+ ++    +KI DFG      D+ +     V T ++ APE+ +    Y++ +D+WS+G +  E+L G   +   D +  L  ++   GTP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>3.17232e-11</Hsp_evalue>
      <Hsp_query-from>504</Hsp_query-from>
      <Hsp_query-to>1127</Hsp_query-to>
      <Hsp_hit-from>356</Hsp_hit-from>
      <Hsp_hit-to>600</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>59</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>51</Hsp_gaps>
      <Hsp_align-len>252</Hsp_align-len>
      <Hsp_qseq>PRRYVNLTS-VGSGAYGSVCSSLDTK-----------------TGMKVAVKKL---SRPFQSVIHAKRTYRELRLLKHMKHENVIGLMDVFTPNSS--------------LEEFDDLIRNVASWHVPSCEGSTLPVSVNS------YIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDEMTG---YVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTP</Hsp_qseq>
      <Hsp_hseq>PRPYFQLVEKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQPKKQLI-----MNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEI-VNQKGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIAN-NGSP</Hsp_hseq>
      <Hsp_midline>PR Y  L    G GA G+V  S   K                  G +VA+K++    +P + +I       EL ++   + EN++  ++ +  +                 +  D + R+    H      + +   V        ++H+  IIHRD+K  N+ +N    +KI DFG      ++ +     V T ++ APEI +N   Y++ VD+WS+G ++ E++ G   +   D +  L  I    G+P</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>3.18235e-11</Hsp_evalue>
      <Hsp_query-from>822</Hsp_query-from>
      <Hsp_query-to>1112</Hsp_query-to>
      <Hsp_hit-from>461</Hsp_hit-from>
      <Hsp_hit-to>559</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>100</Hsp_align-len>
      <Hsp_qseq>IHSAGIIHRDLKPSNLAVNEDCELKILDFGLAR---HADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQ</Hsp_qseq>
      <Hsp_hseq>LHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLG-LGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQ</Hsp_hseq>
      <Hsp_midline>+H   +++RDLKP N+ ++    + + DFGL +     DD+   +  T  Y APE++L  + Y + VD W++G ++ E+LTG   +   D      KILQ</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.3882</Hsp_bit-score>
      <Hsp_score>150</Hsp_score>
      <Hsp_evalue>6.0817e-11</Hsp_evalue>
      <Hsp_query-from>819</Hsp_query-from>
      <Hsp_query-to>1058</Hsp_query-to>
      <Hsp_hit-from>131</Hsp_hit-from>
      <Hsp_hit-to>213</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>83</Hsp_align-len>
      <Hsp_qseq>YIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDEMT--GYVATRWYRAPEIMLNWMH-YNQTVDIWSVGCIMAELLTG</Hsp_qseq>
      <Hsp_hseq>YLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKG</Hsp_hseq>
      <Hsp_midline>Y+H    IHRD+K +N+ +NE+  +K+ DFG++ H    +    +V T ++ APE++   +  YN+  DIWS+G    ELL G</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>1.44933e-10</Hsp_evalue>
      <Hsp_query-from>804</Hsp_query-from>
      <Hsp_query-to>1064</Hsp_query-to>
      <Hsp_hit-from>126</Hsp_hit-from>
      <Hsp_hit-to>220</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>56</Hsp_positive>
      <Hsp_gaps>8</Hsp_gaps>
      <Hsp_align-len>95</Hsp_align-len>
      <Hsp_qseq>VSVNSYIH-SAGIIHRDLKPSNLAVNEDCELKILDFGLA---RHADDEMTGYVATRW---YRAPEIMLNWM-HYNQTVDIWSVGCIMAELLTGRT</Hsp_qseq>
      <Hsp_hseq>VSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQT</Hsp_hseq>
      <Hsp_midline>VS  +Y+H   G+ HRD+KP N+ ++++  LK+ DFGLA   R  D  +   +  R    Y APE++ +   +Y    DIWS+G ++  LLTG+T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>61.2326</Hsp_bit-score>
      <Hsp_score>147</Hsp_score>
      <Hsp_evalue>1.70927e-10</Hsp_evalue>
      <Hsp_query-from>822</Hsp_query-from>
      <Hsp_query-to>1058</Hsp_query-to>
      <Hsp_hit-from>458</Hsp_hit-from>
      <Hsp_hit-to>538</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>4</Hsp_gaps>
      <Hsp_align-len>82</Hsp_align-len>
      <Hsp_qseq>IHSAGIIHRDLKPSNLAVNEDCELKILDFGLAR---HADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTG</Hsp_qseq>
      <Hsp_hseq>LHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLG-QGYTKTVDWWTLGILLYEMMTG</Hsp_hseq>
      <Hsp_midline>+H   +I+RDLKP N+ ++    + + DFGL +     +D+   +  T  Y APEI+L    Y +TVD W++G ++ E++TG</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YMR216C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:698811:701039:-1 gene:YMR216C transcript:YMR216C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKY1 description:SR protein kinase (SRPK); involved in regulating proteins involved in mRNA metabolism and cation homeostasis; similar to human SRPK1 [Source:SGD;Acc:S000004829]</Hit_def>
  <Hit_accession>YMR216C</Hit_accession>
  <Hit_len>742</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>2.3792e-10</Hsp_evalue>
      <Hsp_query-from>858</Hsp_query-from>
      <Hsp_query-to>1325</Hsp_query-to>
      <Hsp_hit-from>540</Hsp_hit-from>
      <Hsp_hit-to>706</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>27</Hsp_gaps>
      <Hsp_align-len>175</Hsp_align-len>
      <Hsp_qseq>PSNLAVNEDCELKILDFGLARHADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLF-PGTDHI-----NQLVKILQLTGTPPQYLIDRMQSKEARNYIQS---LPYTQKRDF---KDVFLGANPL-------VVDLLERMLVLDTDQRITAAEALVHQYF</Hsp_qseq>
      <Hsp_hseq>PENL-----IQIKIADLGNACWYDEHYTNSIQTREYRSPEVLLG-APWGCGADIWSTACLIFELITGDFLFEPDEGHSYTKDDDHIAQIIELLGELPSYLL--RNGKYTRTFFNSRGLLRNISKLKFWPLEDVLTEKYKFSKDEAKEISDFLSPMLQLDPRKRADAGGLVNHPWL</Hsp_hseq>
      <Hsp_midline>P NL      ++KI D G A   D+  T  + TR YR+PE++L    +    DIWS  C++ EL+TG  LF P   H      + + +I++L G  P YL+     K  R +  S   L    K  F   +DV              + D L  ML LD  +R  A   + H + </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>2.58894e-10</Hsp_evalue>
      <Hsp_query-from>513</Hsp_query-from>
      <Hsp_query-to>1145</Hsp_query-to>
      <Hsp_hit-from>824</Hsp_hit-from>
      <Hsp_hit-to>1046</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>96</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>230</Hsp_align-len>
      <Hsp_qseq>YVNLTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPF---QSVIHAKRTYRELRLLK-HMKHENVIGLMDVF-TPNSSLEEFDDLIRNVASWHVPSCEGSTLPVSVNS--------YIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDEM------TGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLID</Hsp_qseq>
      <Hsp_hseq>FVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCK---DEMWYGNRTSTFCGTPEFMAPEI-LKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAIL---TDEPLYPID</Hsp_hseq>
      <Hsp_midline>+V L  +G G +G V  S    T    A+K L +        I + R  +++ LL    KH  +  L   F T N      + +      WHV +   S       +        Y H  G+I+RDLK  N+ +  +  +KI D+GL +   DEM      + +  T  + APEI L    Y + VD W+ G ++ ++L  ++ F G D       IL      P Y ID</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.077</Hsp_bit-score>
      <Hsp_score>144</Hsp_score>
      <Hsp_evalue>4.90404e-10</Hsp_evalue>
      <Hsp_query-from>513</Hsp_query-from>
      <Hsp_query-to>1070</Hsp_query-to>
      <Hsp_hit-from>133</Hsp_hit-from>
      <Hsp_hit-to>379</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>63</Hsp_gaps>
      <Hsp_align-len>248</Hsp_align-len>
      <Hsp_qseq>YVNLTSVGSGAYGSVCSSLDTKTGMKVAVK------KLSRPFQSVIHAKRTY------RELRLLKHMKHENVIGLMDVFTPNSSLEEF---DDLIRNVASWHVPSC-----EGSTLPVSVNS-------------YIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHA-------------DDEMTGYVATRWYRAPEIMLN---WMHYNQT-------------VDIWSVGCIMAELLTGRTLF</Hsp_qseq>
      <Hsp_hseq>YEIIKELGHGQHGKVKLARDILSKQLVAIKIVDRHEKKQRKFFTFIKSSKISENDKIKREIAIMKKCHHKHVVQLIEVLDDLKSRKIYLVLEYCSRGEVKWCPPDCMESDAKGPSL-LSFQETREILRGVVLGLEYLHYQGIIHRDIKPANLLISGDGTVKISDFGVSLAASSTNSSDSSESLDELELAKTVGTPAFFAPEMCLGEDAFTRYNLTKENLFRGSCISFMIDIWAVGVTLYCLLFGMLPF</Hsp_hseq>
      <Hsp_midline>Y  +  +G G +G V  + D  +   VA+K      K  R F + I + +        RE+ ++K   H++V+ L++V     S + +   +   R    W  P C     +G +L +S                Y+H  GIIHRD+KP+NL ++ D  +KI DFG++  A             + E+   V T  + APE+ L    +  YN T             +DIW+VG  +  LL G   F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.151</Hsp_bit-score>
      <Hsp_score>139</Hsp_score>
      <Hsp_evalue>9.35894e-10</Hsp_evalue>
      <Hsp_query-from>819</Hsp_query-from>
      <Hsp_query-to>1070</Hsp_query-to>
      <Hsp_hit-from>217</Hsp_hit-from>
      <Hsp_hit-to>301</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>3</Hsp_gaps>
      <Hsp_align-len>86</Hsp_align-len>
      <Hsp_qseq>YIHSAGIIHRDLKPSNLAVNEDCELKILDFG--LARHADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLF</Hsp_qseq>
      <Hsp_hseq>YMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPE-MVESREYDHTIDAWALGVLAFELLTGAPPF</Hsp_hseq>
      <Hsp_midline>Y+H   IIHRD+KP N+ +  +  +K+ DFG  +    ++       T  Y +PE M+    Y+ T+D W++G +  ELLTG   F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>71</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>9.96848e-10</Hsp_evalue>
      <Hsp_query-from>522</Hsp_query-from>
      <Hsp_query-to>1094</Hsp_query-to>
      <Hsp_hit-from>844</Hsp_hit-from>
      <Hsp_hit-to>1070</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>56</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>54</Hsp_gaps>
      <Hsp_align-len>236</Hsp_align-len>
      <Hsp_qseq>LTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKRTYRELRL------------LKHMKHENVIGLMDVF---------TP----NSSLEEFD------DLIRNVASWHVPSCEGSTLPVSVNSYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARH-ADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIM-------------AELLTGRTLFPGTDHINQ</Hsp_qseq>
      <Hsp_hseq>LQVMGEGAYGKVNLCIHNREHYIVVIKMI---FKERILVDTWVRDRKLGTIPSEIQIMATLNKNSQENILKLLDFFEDDDYYYIETPVHGETGSIDLFDVIEFKKDMVEHEAKLVFKQVVASI------KHLHDQGIVHRDIKDENVIVDSHGFVKLIDFGSAAYIKSGPFDVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLYTIIYKENPYYNIDEILEGELRFDKSEHVSE</Hsp_hseq>
      <Hsp_midline>L  +G GAYG V   +  +    V +K +   F+  I      R+ +L            L     EN++ L+D F         TP      S++ FD      D++ + A         S        ++H  GI+HRD+K  N+ V+    +K++DFG A +        +V T  Y APE++    +  +  DIW++G ++              E+L G   F  ++H+++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>72</Hit_num>
  <Hit_id>YNL183C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:293137:295509:-1 gene:YNL183C transcript:YNL183C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NPR1 description:Protein kinase; stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p; negatively regulates Ldb19p-mediated endocytosis through phosphorylation of Ldb19p, which prevents its association with the plasma membrane; Npr1p activity is negatively regulated via phosphorylation by the TOR complex; NPR1 has a paralog, PRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005127]</Hit_def>
  <Hit_accession>YNL183C</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>1.02424e-09</Hsp_evalue>
      <Hsp_query-from>594</Hsp_query-from>
      <Hsp_query-to>1169</Hsp_query-to>
      <Hsp_hit-from>465</Hsp_hit-from>
      <Hsp_hit-to>685</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>58</Hsp_identity>
      <Hsp_positive>93</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>226</Hsp_align-len>
      <Hsp_qseq>AVKKLSRPFQSVIHAKRTY-----RELRLLKHMKHENVIGLMDVFTPNSSLEE---------FDDLIRNVASWHVPSCEGSTLPVSVNSYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLA-------RHADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGR-------------TLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEAR</Hsp_qseq>
      <Hsp_hseq>AVKEFRTKFEN--ESKRDYVKKITSEYCIGTTLNHPNIIETIEIVYENDRILQVMEYCEYDLFAIVMSNKMSYEEICCCFKQILTGVQ-YLHSIGLAHRDLKLDNCVINEKGIVKLIDFGAAVVFSYPFSKNLVEASGIVGSDPYLAPEVCIFAKYDPRPVDIWSSAIIFACMILKKFPWKIPKLRDNSFKLFCSGRDCDSLSSLVTRTPDPPSY--DESHSTEKK</Hsp_hseq>
      <Hsp_midline>AVK+    F++   +KR Y      E  +   + H N+I  +++   N  + +         F  ++ N  S+    C    +   V  Y+HS G+ HRDLK  N  +NE   +K++DFG A            E +G V +  Y APE+ +   +  + VDIWS   I A ++  +              LF      + L  ++  T  PP Y  D   S E +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>73</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.5362</Hsp_bit-score>
      <Hsp_score>140</Hsp_score>
      <Hsp_evalue>1.46532e-09</Hsp_evalue>
      <Hsp_query-from>819</Hsp_query-from>
      <Hsp_query-to>1109</Hsp_query-to>
      <Hsp_hit-from>147</Hsp_hit-from>
      <Hsp_hit-to>245</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>49</Hsp_positive>
      <Hsp_gaps>2</Hsp_gaps>
      <Hsp_align-len>99</Hsp_align-len>
      <Hsp_qseq>YIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDEMT--GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKIL</Hsp_qseq>
      <Hsp_hseq>YAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTRECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIV</Hsp_hseq>
      <Hsp_midline>Y HS   +HRDLK  N+ ++++   K+ DFG  R    + T      T  Y APE++    +    +DIWS+G I+  L+TG   F   D      KI+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>74</Hit_num>
  <Hit_id>YDL028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:400997:403291:-1 gene:YDL028C transcript:YDL028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MPS1 description:Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]</Hit_def>
  <Hit_accession>YDL028C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>3.29239e-09</Hsp_evalue>
      <Hsp_query-from>822</Hsp_query-from>
      <Hsp_query-to>1109</Hsp_query-to>
      <Hsp_hit-from>554</Hsp_hit-from>
      <Hsp_hit-to>667</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>57</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>116</Hsp_align-len>
      <Hsp_qseq>IHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDEMTGY-----VATRWYRAPEIMLNWMHYNQT---------------VDIWSVGCIMAELLTGRTLFPGTDHINQLVKIL</Hsp_qseq>
      <Hsp_hseq>VHDAGIVHSDLKPANFVLVKGI-LKIIDFGIANAVPEHTVNIYRETQIGTPNYMAPEALV-AMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYGKPPYGSFQGQNRLLAIM</Hsp_hseq>
      <Hsp_midline>+H AGI+H DLKP+N  + +   LKI+DFG+A    +          + T  Y APE ++  M+Y Q                 D+WS GCI+ +++ G+  +      N+L+ I+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>75</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>4.35873e-09</Hsp_evalue>
      <Hsp_query-from>507</Hsp_query-from>
      <Hsp_query-to>1079</Hsp_query-to>
      <Hsp_hit-from>175</Hsp_hit-from>
      <Hsp_hit-to>418</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>57</Hsp_gaps>
      <Hsp_align-len>246</Hsp_align-len>
      <Hsp_qseq>RRYVNLTSVGSGAYGSV--CSSLDTK--TGMKVAVKKLSRPFQSVIH---------AKRTYRELRLLKHMKHENVIGLMDVFTPNSSLEEFDDLIRNVASWHVPSCEGSTLPVSVNSYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLA-----------------------------RHADDEMTGY---------VATRWYRAPEIM----LNWMHYNQTVDIWSVGCIMAELLTGRTLFPGT</Hsp_qseq>
      <Hsp_hseq>RDFEMITQVGQGGYGQVYLARKKDTKEVCALKILNKKLLFKLNETKHVLTERDILTTTRSEWLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINTRCLKSGHA-RFYISEMFCAVNA-LHDLGYTHRDLKPENFLIDAKGHIKLTDFGLAAGTISNERIESMKIRLEKIKDLEFPAFTEKSIEDRRKMYNQLREKEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGS</Hsp_hseq>
      <Hsp_midline>R +  +T VG G YG V      DTK    +K+  KKL        H           R+   ++LL   +    + L   F P           R + S H      S +  +VN+ +H  G  HRDLKP N  ++    +K+ DFGLA                             +  +D    Y          A     +P+ M    L    Y+ TVD WS+GC++ E L G T F G+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>76</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.6102</Hsp_bit-score>
      <Hsp_score>135</Hsp_score>
      <Hsp_evalue>4.6977e-09</Hsp_evalue>
      <Hsp_query-from>462</Hsp_query-from>
      <Hsp_query-to>1196</Hsp_query-to>
      <Hsp_hit-from>153</Hsp_hit-from>
      <Hsp_hit-to>427</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>122</Hsp_positive>
      <Hsp_gaps>52</Hsp_gaps>
      <Hsp_align-len>286</Hsp_align-len>
      <Hsp_qseq>GFCRQELNKTVWEVPRRYVNLTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAK--RTYRELRLLKHMKHENVIGLMDVFTP-NSSLEEFDDLI--RNVASWHVPS------CEGSTLPVSVN-----SYIHSAGIIHRDLKPSN--LAVNEDCELKIL-DFGLARHAD---DEMTGYVATRWYRAPEI----------------MLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTD---HINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSLPYT</Hsp_qseq>
      <Hsp_hseq>GFLR-EVDQ--WEITNRIV-----GNGTFGHVLITHNSKERDEDVCYHPENYAVKIIKLKPNKFDKEARILLRLDHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGISPFYGDGSERSIIQNAKIGKLNFKLKQWDI---VSDNAKSFVKDLLQT</Hsp_hseq>
      <Hsp_midline>GF R E+++  WE+  R V     G+G +G V  + ++K   +            +I  K  +  +E R+L  + H N+I +   F   N+ L  F DLI   ++ S+           E  +L +        +Y+H   I+HRDLK  N  L   E C   +L DFG+A+  +   + M   V T  Y APE+                 L    Y+   D+WS+G I   +LTG + F G      I Q  KI +L     Q+ I    S  A+++++ L  T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>77</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>3.02433e-08</Hsp_evalue>
      <Hsp_query-from>819</Hsp_query-from>
      <Hsp_query-to>1112</Hsp_query-to>
      <Hsp_hit-from>611</Hsp_hit-from>
      <Hsp_hit-to>731</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>34</Hsp_identity>
      <Hsp_positive>53</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>122</Hsp_align-len>
      <Hsp_qseq>YIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDE------------------------MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQ</Hsp_qseq>
      <Hsp_hseq>YLHLLGFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRGNGH-TAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILK</Hsp_hseq>
      <Hsp_midline>Y+H  G I+RDLKP N+ +++   + + DF L+  A D                            +V T  Y APE++    H    VD W++G ++ E+L G T F G +       IL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>78</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>3.69936e-08</Hsp_evalue>
      <Hsp_query-from>678</Hsp_query-from>
      <Hsp_query-to>1070</Hsp_query-to>
      <Hsp_hit-from>143</Hsp_hit-from>
      <Hsp_hit-to>289</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>38</Hsp_identity>
      <Hsp_positive>68</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>147</Hsp_align-len>
      <Hsp_qseq>KHENVIGLMDVFTPNSSLE--EFDDLIRNVASWHVPSCEGS-----TLPVSVNSYIHSAGIIHRDLKPSNLAVNE-DCELKILDFGLARHADDEMTGYVATRWYRAPEIMLNWMHYNQ--------TVDIWSVGCIMAELLTGRTLF</Hsp_qseq>
      <Hsp_hseq>RHQNIAALLDFFDSYIIMEYCSGGDLYEAIKADAVPKKTKSITHIITQIMDAIEYVHNKGIYHRDIKPENILISGIDWTIKLTDWGLATTDKTSMDRNVGSERYMSPELFDSNLDIKERKEPYDCAKVDLWAMGIVFLNIVFHKNPF</Hsp_hseq>
      <Hsp_midline>+H+N+  L+D F     +E     DL   + +  VP    S     T  +    Y+H+ GI HRD+KP N+ ++  D  +K+ D+GLA      M   V +  Y +PE+  + +   +         VD+W++G +   ++  +  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>79</Hit_num>
  <Hit_id>YAR018C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:170396:171703:-1 gene:YAR018C transcript:YAR018C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN3 description:Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol [Source:SGD;Acc:S000000071]</Hit_def>
  <Hit_accession>YAR018C</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>3.82773e-08</Hsp_evalue>
      <Hsp_query-from>504</Hsp_query-from>
      <Hsp_query-to>1106</Hsp_query-to>
      <Hsp_hit-from>21</Hsp_hit-from>
      <Hsp_hit-to>300</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>105</Hsp_positive>
      <Hsp_gaps>81</Hsp_gaps>
      <Hsp_align-len>281</Hsp_align-len>
      <Hsp_qseq>PR-RYVNLTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKRTYRELRLLKHMKHENVIGLMD-----------VFTPNSSLEEFDDLIRNVASWH--VPS----------------CE-GSTLPVSVNSYIHSAG-------IIHRDLKPSNL---------AVNEDCE------------------------------LKILDFGLARHADDEM---TGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKI</Hsp_qseq>
      <Hsp_hseq>PRSEYQVLEEIGRGSFGSVRKVIHIPTKKLLVRKDIKYGHMNSKERQQLIAECSILSQLKHENIVEFYNWDFDEQKEVLYLYMEYCSRGDLSQMIKHYKQEHKYIPEKIVWGILAQLLTALYKCHYGVELPTLTTIYDRMKPPVKGKNIVIHRDLKPGNIFLSYDDSDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLAKSLETSIQFATTYVGTPYYMSPEVLMD-QPYSPLSDIWSLGCVIFEMCSLHPPFQAKNYLELQTKI</Hsp_hseq>
      <Hsp_midline>PR  Y  L  +G G++GSV   +   T   +  K +     +    ++   E  +L  +KHEN++   +           ++    S  +   +I++    H  +P                 C  G  LP     Y            +IHRDLKP N+          +NE  +                              +K+ DFGLA+  +  +   T YV T +Y +PE++++   Y+   DIWS+GC++ E+ +    F   +++    KI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>80</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.5286</Hsp_bit-score>
      <Hsp_score>127</Hsp_score>
      <Hsp_evalue>5.16982e-08</Hsp_evalue>
      <Hsp_query-from>510</Hsp_query-from>
      <Hsp_query-to>1049</Hsp_query-to>
      <Hsp_hit-from>443</Hsp_hit-from>
      <Hsp_hit-to>646</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>98</Hsp_positive>
      <Hsp_gaps>38</Hsp_gaps>
      <Hsp_align-len>211</Hsp_align-len>
      <Hsp_qseq>RYVNLTSVGSGAYGSVCSSLDTKTGMKVAVKKLS-RPFQSVIHAKRTYRELRLLKHM---------------------KHENVIGLMDVFTPNSSLEEF--DDLI---RNVASWHVPSCEGSTLPVSVN-SYIH-SAGIIHRDLKPSNLAVNEDCELKILDFGLARH--ADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAEL</Hsp_qseq>
      <Hsp_hseq>KFTNVHSIGKGQFSTVYQVTFAQTNKKYAIKAIKPNKYNSL---KRILLEIKILNEVTNQITMDQEGKEYIIDYISSWKFQNSYYIMTELCENGNLDGFLQEQVIAKKKRLEDWRIWKI---IVELSLALRFIHDSCHIVHLDLKPANVMITFEGNLKLGDFGMATHLPLEDKSFENEGDREYIAPEIISDCT-YDYKADIFSLGLMIVEI</Hsp_hseq>
      <Hsp_midline>++ N+ S+G G + +V      +T  K A+K +    + S+   KR   E+++L  +                     K +N   +M     N +L+ F  + +I   + +  W +       + +S+   +IH S  I+H DLKP+N+ +  +  LK+ DFG+A H   +D+       R Y APEI+ +   Y+   DI+S+G ++ E+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>81</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.7582</Hsp_bit-score>
      <Hsp_score>125</Hsp_score>
      <Hsp_evalue>8.83811e-08</Hsp_evalue>
      <Hsp_query-from>804</Hsp_query-from>
      <Hsp_query-to>1187</Hsp_query-to>
      <Hsp_hit-from>434</Hsp_hit-from>
      <Hsp_hit-to>578</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>40</Hsp_identity>
      <Hsp_positive>63</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>149</Hsp_align-len>
      <Hsp_qseq>VSVNSYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDE---------------------MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSL</Hsp_qseq>
      <Hsp_hseq>VAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGH-TAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKFPH---DKEVSKNCKDLIKKL</Hsp_hseq>
      <Hsp_midline>V+   Y+H  G I+RDLKP N+ +++   + + DF L+  A                           +V T  Y APE++    H    VD W++G ++ E+L G T F G +       IL      P    D+  SK  ++ I+ L</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>82</Hit_num>
  <Hit_id>YFL029C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:78055:79161:-1 gene:YFL029C transcript:YFL029C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CAK1 description:Cyclin-dependent kinase-activating kinase; required for passage through the cell cycle; phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases [Source:SGD;Acc:S000001865]</Hit_def>
  <Hit_accession>YFL029C</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>1.61608e-07</Hsp_evalue>
      <Hsp_query-from>816</Hsp_query-from>
      <Hsp_query-to>1064</Hsp_query-to>
      <Hsp_hit-from>145</Hsp_hit-from>
      <Hsp_hit-to>242</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>52</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>99</Hsp_align-len>
      <Hsp_qseq>SYIHSAGIIHRDLKPSNLAVNEDC-----ELKILDFGL-----------ARHADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRT</Hsp_qseq>
      <Hsp_hseq>AFLHENKIIHRDIKPQNIMLTNNTSTVSPKLYIIDFGISYDMANNSQTSAEPMDSKVTD-ISTGIYKAPEVLFGVKCYDGGVDVWSLLIIISQWFQRET</Hsp_hseq>
      <Hsp_midline>+++H   IIHRD+KP N+ +  +      +L I+DFG+           A   D ++T  ++T  Y+APE++     Y+  VD+WS+  I+++     T</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>83</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>2.69705e-07</Hsp_evalue>
      <Hsp_query-from>522</Hsp_query-from>
      <Hsp_query-to>1178</Hsp_query-to>
      <Hsp_hit-from>363</Hsp_hit-from>
      <Hsp_hit-to>600</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>57</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>244</Hsp_align-len>
      <Hsp_qseq>LTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKRTYRELRLLKHMKHENVIGLMDVF------------TPNSSLEEFDDLIRNVASWHVPSCEGSTLPVSVNSYIHSA-------GIIHRDLKPSNLAVNED-CELKILDFGLARHADDEMTGY-VATRWYRAPEIM--LNWMHYNQTV--DIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLTGTPPQYLIDRMQSKEARNYI</Hsp_qseq>
      <Hsp_hseq>LDELGHGNYGNVSKVLHKPTNVIMATKEVRLELDEA-KFRQILMELEVLHKCNSPYIVDFYGAFFIEGAVYMCMEYMDGGSLDKIYDESSEIGGIDEPQ-----LAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSANQGTVKLCDFGVSGNLVASLAKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYPPETYDNIFSQLSAIVDGPPPRLPSDKFSSDAQDFV</Hsp_hseq>
      <Hsp_midline>L  +G G YG+V   L   T + +A K++          ++   EL +L       ++     F                SL++  D    +     P      L    N+ IH          IIHRD+KP+N+  + +   +K+ DFG++ +    +    +  + Y APE +  LN      TV  DIWS+G  + E+  GR  +P   + N   ++  +   PP  L     S +A++++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>84</Hit_num>
  <Hit_id>YDL214C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:74446:76545:-1 gene:YDL214C transcript:YDL214C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR2 description:Serine/threonine protein kinase; inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance; PRR2 has a paralog, NPR1, that arose from the whole genome duplication [Source:SGD;Acc:S000002373]</Hit_def>
  <Hit_accession>YDL214C</Hit_accession>
  <Hit_len>699</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>5.20712e-07</Hsp_evalue>
      <Hsp_query-from>819</Hsp_query-from>
      <Hsp_query-to>1073</Hsp_query-to>
      <Hsp_hit-from>474</Hsp_hit-from>
      <Hsp_hit-to>563</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>31</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>92</Hsp_align-len>
      <Hsp_qseq>YIHSAGIIHRDLKPSNLAVNEDCELKILDFGLA-------RHADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFP</Hsp_qseq>
      <Hsp_hseq>YLHDIGLSHRDLKLDNCVVTRRGILKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFYFNEYDPRALDVWSVGIIFFCMITRR--FP</Hsp_hseq>
      <Hsp_midline>Y+H  G+ HRDLK  N  V     LK++DFG +            E  G V +  Y +PE+     +  + +D+WSVG I   ++T R  FP</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>85</Hit_num>
  <Hit_id>YJL165C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:106894:109461:-1 gene:YJL165C transcript:YJL165C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HAL5 description:Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters; HAL5 has a paralog, KKQ8, that arose from the whole genome duplication [Source:SGD;Acc:S000003701]</Hit_def>
  <Hit_accession>YJL165C</Hit_accession>
  <Hit_len>855</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>5.78812e-07</Hsp_evalue>
      <Hsp_query-from>819</Hsp_query-from>
      <Hsp_query-to>1070</Hsp_query-to>
      <Hsp_hit-from>678</Hsp_hit-from>
      <Hsp_hit-to>769</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>30</Hsp_identity>
      <Hsp_positive>47</Hsp_positive>
      <Hsp_gaps>10</Hsp_gaps>
      <Hsp_align-len>93</Hsp_align-len>
      <Hsp_qseq>YIHSAGIIHRDLKPSNLAVNEDCELKILDFGLA--------RHADDEMTGYVATRWYRAPEIMLNWMHYN-QTVDIWSVGCIMAELLTGRTLF</Hsp_qseq>
      <Hsp_hseq>YMHDHGIAHCDLKPENILFQPNGLLKICDFGTSSVFQTAWEKHVHFQ-SGAMGSEPYVAPEEFIRDAEYDPRLVDCWSCGIVYCTMVMGQYLW</Hsp_hseq>
      <Hsp_midline>Y+H  GI H DLKP N+    +  LKI DFG +        +H   + +G + +  Y APE  +    Y+ + VD WS G +   ++ G+ L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>86</Hit_num>
  <Hit_id>YGL158W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:207033:208571:1 gene:YGL158W transcript:YGL158W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RCK1 description:Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000003126]</Hit_def>
  <Hit_accession>YGL158W</Hit_accession>
  <Hit_len>512</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>1.87498e-06</Hsp_evalue>
      <Hsp_query-from>819</Hsp_query-from>
      <Hsp_query-to>1106</Hsp_query-to>
      <Hsp_hit-from>249</Hsp_hit-from>
      <Hsp_hit-to>368</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>35</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>121</Hsp_align-len>
      <Hsp_qseq>YIHSAGIIHRDLKPSNL--------AVNEDCE----------------LKILDFGLARHADDEMTGY-VATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKI</Hsp_qseq>
      <Hsp_hseq>HMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLRNNTAKTPCGTIEYVASEVFTS-KRYSMKVDMWSIGCVLFTLLCGYPPFYEKNEKTLLKKI</Hsp_hseq>
      <Hsp_midline>++H  GI+HRD+KP NL         ++ D +                +K++DFGLA+   +        T  Y A E+  +   Y+  VD+WS+GC++  LL G   F   +    L KI</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>87</Hit_num>
  <Hit_id>YKL048C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:347214:349136:-1 gene:YKL048C transcript:YKL048C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ELM1 description:Serine/threonine protein kinase; regulates the orientation checkpoint, the morphogenesis checkpoint and the metabolic switch from fermentative to oxidative metabolism by phosphorylating the activation loop of Kin4p, Hsl1p and Snf4p respectively; cooperates with Hsl7p in recruiting Hsl1p to the septin ring, a prerequisite for subsequent recruitment, phosphorylation, and degradation of Swe1p; forms part of the bud neck ring; regulates cytokinesis [Source:SGD;Acc:S000001531]</Hit_def>
  <Hit_accession>YKL048C</Hit_accession>
  <Hit_len>640</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>2.21716e-06</Hsp_evalue>
      <Hsp_query-from>819</Hsp_query-from>
      <Hsp_query-to>1118</Hsp_query-to>
      <Hsp_hit-from>249</Hsp_hit-from>
      <Hsp_hit-to>370</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>59</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>122</Hsp_align-len>
      <Hsp_qseq>YIHSAGIIHRDLKPSNLAVNEDCEL-KILDFGL------------ARHAD---DEMTGYVATRWYRAPEIM------LNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLVKILQLT</Hsp_qseq>
      <Hsp_hseq>YLHSQGCIHRDIKPSNILLDEEEKVAKLSDFGSCIFTPQSLPFSDANFEDCFQRELNKIVGTPAFIAPELCHLGNSKRDFVTDGFKLDIWSLGVTLYCLLYNELPFFGENEFETYHKIIEVS</Hsp_hseq>
      <Hsp_midline>Y+HS G IHRD+KPSN+ ++E+ ++ K+ DFG             A   D    E+   V T  + APE+        +++     +DIWS+G  +  LL     F G +      KI++++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>88</Hit_num>
  <Hit_id>YKL168C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:131288:133462:-1 gene:YKL168C transcript:YKL168C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KKQ8 description:Putative serine/threonine protein kinase with unknown cellular role; KKQ8 has a paralog, HAL5, that arose from the whole genome duplication [Source:SGD;Acc:S000001651]</Hit_def>
  <Hit_accession>YKL168C</Hit_accession>
  <Hit_len>724</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.7506</Hsp_bit-score>
      <Hsp_score>112</Hsp_score>
      <Hsp_evalue>3.21274e-06</Hsp_evalue>
      <Hsp_query-from>819</Hsp_query-from>
      <Hsp_query-to>1070</Hsp_query-to>
      <Hsp_hit-from>553</Hsp_hit-from>
      <Hsp_hit-to>644</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>29</Hsp_identity>
      <Hsp_positive>45</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>95</Hsp_align-len>
      <Hsp_qseq>YIHSAGIIHRDLKPSNLAVNEDCELKILDFGLAR----------HADDEMTGYVATRWYRAPEIMLNWMHYN-QTVDIWSVGCIMAELLTGRTLF</Hsp_qseq>
      <Hsp_hseq>FMHDHGIAHCDLKPENILFYPHGLLKICDFGTSSVFQTAWERRVHA---QKGIIGSEPYVAPEEFVDGEYYDPRLIDCWSCGVVYITMILGHYLW</Hsp_hseq>
      <Hsp_midline>++H  GI H DLKP N+       LKI DFG +           HA     G + +  Y APE  ++  +Y+ + +D WS G +   ++ G  L+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>93</Statistics_hsp-len>
      <Statistics_eff-space>876401727</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>6</Iteration_iter-num>
  <Iteration_query-ID>Query_6</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054770-RA transcript Note:&quot;Similar to Mapk12 Mitogen-activated protein kinase 12 (Rattus norvegicus)&quot; offset:407 AED:0.05 eAED:0.05 QI:407|0.77|0.9|1|0.55|0.7|10|2191|335</Iteration_query-def>
  <Iteration_query-len>3606</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YLR113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:371620:372927:1 gene:YLR113W transcript:YLR113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HOG1 description:Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]</Hit_def>
  <Hit_accession>YLR113W</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>253.447</Hsp_bit-score>
      <Hsp_score>646</Hsp_score>
      <Hsp_evalue>6.87007e-75</Hsp_evalue>
      <Hsp_query-from>420</Hsp_query-from>
      <Hsp_query-to>1382</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>343</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>139</Hsp_identity>
      <Hsp_positive>200</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>350</Hsp_align-len>
      <Hsp_qseq>SSRKGFYRIEINKMVWEVPKRYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQEMTGYVVTRWYRAPEVILNWMHYT------------------------QTDMDQLMLILKLTGTPPQYLVDRM-DENVSCLLHFITRGP---GTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFFSX-XXXXXXXXXXXXYDQTFEGVELETSEWKSLIHVEITTF</Hsp_qseq>
      <Hsp_hseq>TTNEEFIRTQIFGTVFEITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIF-----LSPLEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENT---LKFVTSLPHRDPIPFSERFKTVEPDAVDLLEKMLVFDPKKRITAADALAHPYSAPYHDPTDEPVADAKFDWHFNDADLPVDTWRVMMYSEILDF</Hsp_hseq>
      <Hsp_midline>++ + F R +I   V+E+  RY+ L  VG GA+G VCS+ D +T   VA+KK+ +PF + V AKR YREL+LLKH++HEN+I L D+F     L   +D Y V    GTDL ++++        VQY +YQIL+GLKY+HS+G+IHRDLKP N+ +NE+C+LKI DFGLAR  D +MTGYV TR+YRAPE++L W  Y                         +  + Q  +I  L G+PP+ +++ +  EN    L F+T  P         +F      A+DLLEKML  DP++R TA++AL HP+ +       E      +D  F   +L    W+ +++ EI  F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>2</Hit_num>
  <Hit_id>YBL016W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:192451:193512:1 gene:YBL016W transcript:YBL016W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FUS3 description:Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]</Hit_def>
  <Hit_accession>YBL016W</Hit_accession>
  <Hit_len>353</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>204.142</Hsp_bit-score>
      <Hsp_score>518</Hsp_score>
      <Hsp_evalue>1.53633e-58</Hsp_evalue>
      <Hsp_query-from>456</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>4</Hsp_hit-from>
      <Hsp_hit-to>309</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>117</Hsp_identity>
      <Hsp_positive>168</Hsp_positive>
      <Hsp_gaps>65</Hsp_gaps>
      <Hsp_align-len>320</Hsp_align-len>
      <Hsp_qseq>KMVWEVPKRYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQE-------------MTGYVVTRWYRAPEVILNWMHYTQTDMD-------------------------QLMLILKLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQ-FTFYGAA------------AIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>RIVYNISSDFQLKSLLGEGAYGVVCSATHKPTGEIVAIKKI-EPFDKPLFALRTLREIKILKHFKHENIITIFNIQRP-DSFENFNEVYIIQELMQTDLHRVISTQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRA-MDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTP------HSDNDLRCI-----ESPRAREYIKSLPMYPAAPLEKMFPRVNPKGIDLLQRMLVFDPAKRITAKEALEHPYL</Hsp_hseq>
      <Hsp_midline>++V+ +   +     +G GAYG VCS+    TG  VA+KK+  PF   +FA R  RE+++LKH KHEN+I + ++  P D+ + F + Y++   M TDL +++     SDD +QY IYQ L+ +K +H S +IHRDLKP NL +N +C+LK+ DFGLAR  D+              MT YV TRWYRAPEV+L    Y++  MD                         QL+LI  + GTP        D ++ C+       P  R +++    Y AA             IDLL++ML  DP +R TA EAL+HP+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>3</Hit_num>
  <Hit_id>YGR040W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:575398:576504:1 gene:YGR040W transcript:YGR040W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSS1 description:Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]</Hit_def>
  <Hit_accession>YGR040W</Hit_accession>
  <Hit_len>368</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>197.208</Hsp_bit-score>
      <Hsp_score>500</Hsp_score>
      <Hsp_evalue>5.86594e-56</Hsp_evalue>
      <Hsp_query-from>459</Hsp_query-from>
      <Hsp_query-to>1265</Hsp_query-to>
      <Hsp_hit-from>5</Hsp_hit-from>
      <Hsp_hit-to>314</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>122</Hsp_identity>
      <Hsp_positive>177</Hsp_positive>
      <Hsp_gaps>51</Hsp_gaps>
      <Hsp_align-len>315</Hsp_align-len>
      <Hsp_qseq>MVWEVPKRYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHM-KHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQ-----SDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLAR----HADQE------MTGYVVTRWYRAPEVILNWMHYTQTDMD-------------------------QLMLILKLTGTPP-----QYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFFS</Hsp_qseq>
      <Hsp_hseq>ITFDIPSQYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKI-QPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPV-SIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYT-TAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIAN-LPMRPPLPWETVWSK-TDLNPDMIDLLDKMLQFNPDKRISAAEALRHPYLA</Hsp_hseq>
      <Hsp_midline>+ +++P +Y  +  +G GAYGTVCS++   +G KVA+KK+ +PF  ++F  R  RE++LL++  +HEN+I ++D   P  ++D+    YLV   M TDL K++ +        SDD VQY  YQIL+ LK IHS+ +IHRD+KP NL +N +C+LK+ DFGLAR     +D        MT YV TRWYRAPE++L +  YT T MD                         QL LIL++ GTP      Q    R  E ++  L      P    W + T      IDLL+KML  +P++R +A+EAL+HP+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>4</Hit_num>
  <Hit_id>YHR030C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:168890:170344:-1 gene:YHR030C transcript:YHR030C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SLT2 description:Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]</Hit_def>
  <Hit_accession>YHR030C</Hit_accession>
  <Hit_len>484</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>196.823</Hsp_bit-score>
      <Hsp_score>499</Hsp_score>
      <Hsp_evalue>1.19039e-54</Hsp_evalue>
      <Hsp_query-from>465</Hsp_query-from>
      <Hsp_query-to>1265</Hsp_query-to>
      <Hsp_hit-from>17</Hsp_hit-from>
      <Hsp_hit-to>319</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>119</Hsp_identity>
      <Hsp_positive>171</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>306</Hsp_align-len>
      <Hsp_qseq>WEVPKRYSQLFAVGSGAYGTVCSS--MDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMK-HENVIGLVD---VFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQ-SDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLAR-------HADQEMTGYVVTRWYRAPEVILNWMHYTQTD------------------------MDQLMLILKLTGTPPQYLVDRM-DENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFFS</Hsp_qseq>
      <Hsp_hseq>FSVDKRFQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSIN---GLYLYEELMECDMHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPYLS</Hsp_hseq>
      <Hsp_midline>+ V KR+  +  +G GAYG VCS+   +    + VA+KK+   F   +  KR+ REL+LL+H + H+N+  L D   VF P+ +++     YL    M  D+ +I+K G+  +D   Q   YQIL GLKYIHS+ ++HRDLKPGNL VN DC+LKI DFGLAR          Q +T YV TRWYRAPE++L++  YT+                          ++QL  IL++ GTPP   + R+  +NV   +H +   P       +    + A+DLLE+MLA DP++R T  EAL+HP+ S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>5</Hit_num>
  <Hit_id>YKL161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:149386:150687:-1 gene:YKL161C transcript:YKL161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KDX1 description:Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]</Hit_def>
  <Hit_accession>YKL161C</Hit_accession>
  <Hit_len>433</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>160.614</Hsp_bit-score>
      <Hsp_score>405</Hsp_score>
      <Hsp_evalue>8.19516e-43</Hsp_evalue>
      <Hsp_query-from>501</Hsp_query-from>
      <Hsp_query-to>1265</Hsp_query-to>
      <Hsp_hit-from>29</Hsp_hit-from>
      <Hsp_hit-to>319</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>100</Hsp_identity>
      <Hsp_positive>156</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>294</Hsp_align-len>
      <Hsp_qseq>VGSGAYGTVCSSMDLVTGSK--VAVKKLYRPFQSRVFAKRAYRELRLLKHMK-HENVIGLVD---VFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQSDDK-VQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLA-------RHADQEMTGYVVTRWYRAPEVILNWMHYTQTD------------------------MDQLMLILKLTGTPPQYLVDRM-DENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFFS</Hsp_qseq>
      <Hsp_hseq>IGRGSHSLICSSTYTESNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALN---GVYLYEELMECDLSQIIRSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIPGRSFESILPGANPEALELLKKMLEFDPKKRITVEDALEHPYLS</Hsp_hseq>
      <Hsp_midline>+G G++  +CSS    +  +  VA++K+   F +++  KR  REL+LL+H++ H N++ L D   VF PN  L+     YL    M  DLS+I++  ++ +D   Q  IYQIL  LKYIHS+ ++H DLKP NL VN DC+LKI +FGL+       +  D  + GY+ + WY+APE++LN+   T+                          +D L  IL++ GTPP+  +  +  + V   +      PG             A++LL+KML  DP++R T  +AL+HP+ S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>6</Hit_num>
  <Hit_id>YPR054W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:666280:667446:1 gene:YPR054W transcript:YPR054W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SMK1 description:Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258]</Hit_def>
  <Hit_accession>YPR054W</Hit_accession>
  <Hit_len>388</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>152.525</Hsp_bit-score>
      <Hsp_score>384</Hsp_score>
      <Hsp_evalue>2.20288e-40</Hsp_evalue>
      <Hsp_query-from>468</Hsp_query-from>
      <Hsp_query-to>1265</Hsp_query-to>
      <Hsp_hit-from>33</Hsp_hit-from>
      <Hsp_hit-to>338</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>102</Hsp_identity>
      <Hsp_positive>153</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>308</Hsp_align-len>
      <Hsp_qseq>EVPKRYSQLFAVGSGAYGTVCSSM--DLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMK-HENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQ-SDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLAR--HA---------DQEMTGYVVTRWYRAPEVILNWMHYTQT------------------------DMDQLMLILKLTGTPPQYLVDRMDENVSCLLHFITRGPGTRH--WLQ-FTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFFS</Hsp_qseq>
      <Hsp_hseq>SIPGYYEIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGHKNIVNLIDLEIV--TSSPYDGLYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDKDILIKFGTIKAWNLGKNSNNPVYKKIPWSNIFPFASHEAINLIESLLHWDSTHRLNVEQAISHPFLN</Hsp_hseq>
      <Hsp_midline> +P  Y  +  +G GAYGTVCS         +++AVKK+   F   +  KRA REL+ +   K H+N++ L+D+     T   +   Y     +  DL+K++    Q S+  ++Y +YQIL GLKYIHS+ +IHRDLKPGN+    +  LKI DFGLAR  HA            +T YV TRWYRAPE++L+   Y+++                         M Q+  I+K+ GTP + ++ +     +  L   +  P  +   W   F F    AI+L+E +L  D   R    +A+ HPF +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>7</Hit_num>
  <Hit_id>YBR160W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:560078:560974:1 gene:YBR160W transcript:YBR160W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC28 description:Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]</Hit_def>
  <Hit_accession>YBR160W</Hit_accession>
  <Hit_len>298</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>131.724</Hsp_bit-score>
      <Hsp_score>330</Hsp_score>
      <Hsp_evalue>3.21057e-34</Hsp_evalue>
      <Hsp_query-from>483</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>8</Hsp_hit-from>
      <Hsp_hit-to>295</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>97</Hsp_identity>
      <Hsp_positive>139</Hsp_positive>
      <Hsp_gaps>52</Hsp_gaps>
      <Hsp_align-len>300</Hsp_align-len>
      <Hsp_qseq>YSQLFAVGSGAYGTVCSSMDLVTGSK---VAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIM----KHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQEMTGY---VVTRWYRAPEVILNWMHYT------------------------QTDMDQLMLILKLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAA------AIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>YKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSD-----AHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIW----PDIVYLPDF---KPSFPQWRRKDLSQVVPSLDPRGIDLLDKLLAYDPINRISARRAAIHPYF</Hsp_hseq>
      <Hsp_midline>Y +L  VG G YG V  ++DL  G     VA+KK+    +       A RE+ LLK +K +N++ L D+   +         YLV  F+  DL + M    K      D V+  + Q+ KG+ Y HS  I+HRDLKP NL +N+D  LK+ DFGLAR     +  Y   +VT WYRAPEV+L    Y+                         +++DQ+  I ++ GTP + +      ++  L  F    P    W +              IDLL+K+LA DP  R +A  A  HP+F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>8</Hit_num>
  <Hit_id>YDL108W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:267698:268699:1 gene:YDL108W transcript:YDL108W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN28 description:Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]</Hit_def>
  <Hit_accession>YDL108W</Hit_accession>
  <Hit_len>306</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>131.724</Hsp_bit-score>
      <Hsp_score>330</Hsp_score>
      <Hsp_evalue>4.96547e-34</Hsp_evalue>
      <Hsp_query-from>468</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>290</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>95</Hsp_identity>
      <Hsp_positive>147</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>299</Hsp_align-len>
      <Hsp_qseq>EVPKRYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQ--SDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARH--ADQE-MTGYVVTRWYRAPEVILNWMHYT------------------------QTDMDQLMLILKLTGTPPQYLVDRMDENVSCLLHFI---TRGPGTRHWLQFTFYGAA--AIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>KVNMEYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNVIELIDIFMAYDNLN------LVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTP----TDRDWPEVSSFMTYNKLQIYPPPSRDELRKRFIAASEYALDFMCGMLTMNPQKRWTAVQCLESDYF</Hsp_hseq>
      <Hsp_midline>+V   Y++   VG G Y  V       TG K+A+K++            A RE++ L+ M+H NVI L+D+F   D L+      LV+ F+ TDL  ++K      +   ++  +   L+G+ + H + I+HRDLKP NL  + D ++K+ DFGLAR   A  E +T  VVTRWYRAPE++    HYT                        Q D+DQ+ +  +  GTP     DR    VS  + +       P +R  L+  F  A+  A+D +  ML ++P++R TA + L+  +F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>9</Hit_num>
  <Hit_id>YPL031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:492018:493037:-1 gene:YPL031C transcript:YPL031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PHO85 description:Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]</Hit_def>
  <Hit_accession>YPL031C</Hit_accession>
  <Hit_len>305</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>125.176</Hsp_bit-score>
      <Hsp_score>313</Hsp_score>
      <Hsp_evalue>6.75515e-32</Hsp_evalue>
      <Hsp_query-from>480</Hsp_query-from>
      <Hsp_query-to>1265</Hsp_query-to>
      <Hsp_hit-from>6</Hsp_hit-from>
      <Hsp_hit-to>298</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>94</Hsp_identity>
      <Hsp_positive>145</Hsp_positive>
      <Hsp_gaps>65</Hsp_gaps>
      <Hsp_align-len>310</Hsp_align-len>
      <Hsp_qseq>RYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQSD-------DKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHAD---QEMTGYVVTRWYRAPEVILNWMHYTQT------------------------DMDQLMLILKLTGTP-----------PQY---LVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFFS</Hsp_qseq>
      <Hsp_hseq>QFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGT-PSTAIREISLMKELKHENIVRLYDVIHTENKLT------LVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPKYNPNIQQRPPRDLRQVLQPHTKEP----------LDGNLMDFLHGLLQLNPDMRLSAKQALHHPWFA</Hsp_hseq>
      <Hsp_midline>++ QL  +G+G Y TV   ++  TG  VA+K++    +       A RE+ L+K +KHEN++ L DV    + L       LV  FM  DL K M      +       + V+Y  +Q+L+GL + H + I+HRDLKP NL +N+  +LK+ DFGLAR         +  VVT WYRAP+V++    Y+ +                        D +QL LI  + GTP           P+Y   +  R   ++  +L   T+ P               +D L  +L L+P+ R +A +AL HP+F+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>10</Hit_num>
  <Hit_id>YPR161C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:864449:866422:-1 gene:YPR161C transcript:YPR161C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SGV1 description:Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]</Hit_def>
  <Hit_accession>YPR161C</Hit_accession>
  <Hit_len>657</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>130.954</Hsp_bit-score>
      <Hsp_score>328</Hsp_score>
      <Hsp_evalue>1.21517e-31</Hsp_evalue>
      <Hsp_query-from>483</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>60</Hsp_hit-from>
      <Hsp_hit-to>366</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>93</Hsp_identity>
      <Hsp_positive>151</Hsp_positive>
      <Hsp_gaps>53</Hsp_gaps>
      <Hsp_align-len>310</Hsp_align-len>
      <Hsp_qseq>YSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDV-------FTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQSDD--KVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLAR---------------HADQEMTGYVVTRWYRAPEVILNWMHYT------------------------QTDMDQLMLILKLTGTPPQ--YLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>YREDEKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTEEDWAVARYLPGAE--LTTTNYKPTLRERFG-KYLSETGLDFLGQLLALDPYKRLTAMSAKHHPWF</Hsp_hseq>
      <Hsp_midline>Y +   +G G +G V   + L T  +VA+KK+    +  +F   A RE+ +LK + H+N+I L+++        T   + +  + FY+++P+M  DLS ++ + + + +   ++ ++ QIL+GL YIH +  +HRD+K  N+ ++ +  LK+ DFGLAR                +  + T  VVTRWYRAPE++L    YT                        +TD+DQ  +I KL GTP +  + V R        L      P  R      +     +D L ++LALDP +R TA  A  HP+F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>11</Hit_num>
  <Hit_id>YMR139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:546125:547237:1 gene:YMR139W transcript:YMR139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM11 description:Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747]</Hit_def>
  <Hit_accession>YMR139W</Hit_accession>
  <Hit_len>370</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>106.301</Hsp_bit-score>
      <Hsp_score>264</Hsp_score>
      <Hsp_evalue>6.34323e-25</Hsp_evalue>
      <Hsp_query-from>498</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>44</Hsp_hit-from>
      <Hsp_hit-to>322</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>83</Hsp_identity>
      <Hsp_positive>139</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>289</Hsp_align-len>
      <Hsp_qseq>AVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKH-----GKQSDDKVQYLIYQILKGLKYIHS-SGIIHRDLKPGNLAVN-EDCELKILDFGLARH--ADQEMTGYVVTRWYRAPEVILNWMHYT------------------------QTDMDQLMLILKLTGTPPQYLVDRMDEN-VSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>VVGHGSFGVVFATVIQETNEKVAIKKV---LQDKRFKNR---ELEIMKMLSHINIIDLKYFFYERDSQDEIY-LNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILGTPSKQEICSMNPNYMEHKFPQIKPIPLSR---VFKKEDDQTVEFLADVLKYDPLERFNALQCLCSPYF</Hsp_hseq>
      <Hsp_midline> VG G++G V +++   T  KVA+KK+    Q + F  R   EL ++K + H N+I L   F   D+ D+     L++ +M   L + ++H        S  +++Y ++Q+ K L Y+H  + + HRD+KP NL V+ E   LK+ DFG A+     +    Y+ +R+YRAPE+I    +YT                        ++ +DQL+ I+K+ GTP +  +  M+ N +      I   P +R    F       ++ L  +L  DP +R  A + L  P+F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>12</Hit_num>
  <Hit_id>YKL139W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:182958:184544:1 gene:YKL139W transcript:YKL139W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CTK1 description:Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3&apos; end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]</Hit_def>
  <Hit_accession>YKL139W</Hit_accession>
  <Hit_len>528</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>105.916</Hsp_bit-score>
      <Hsp_score>263</Hsp_score>
      <Hsp_evalue>5.30562e-24</Hsp_evalue>
      <Hsp_query-from>483</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>183</Hsp_hit-from>
      <Hsp_hit-to>469</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>79</Hsp_identity>
      <Hsp_positive>139</Hsp_positive>
      <Hsp_gaps>51</Hsp_gaps>
      <Hsp_align-len>299</Hsp_align-len>
      <Hsp_qseq>YSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIM--KHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLAR--HADQEMTGYVVTRWYRAPEVILNWMHY-TQTDM-----------------------DQLMLILKLTGTP-----------PQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>YLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNVSTIKEIM-----VESQKTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKMNSRADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTPTINSWPTLYDMPWFFMIMPQQTTKYVNNFSEK-------FKSVLPSSKCLQLAINLLCYDQTKRFSATEALQSDYF</Hsp_hseq>
      <Hsp_midline>Y ++  VG G YG V  + +  T   VA+KKL    +   F   + RE++LL+   H NV  + ++      ++  +  Y++  +   DLS ++  K  + S  + ++L  Q+L G++Y+H + I+HRD+K  N+ ++    LKI DFGLAR  ++  + T  V+T WYR PE++L   +Y T+ DM                       +Q+  I K+ GTP           P + +    +    + +F  +        +     +  + L   +L  D  +R +A+EALQ  +F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>13</Hit_num>
  <Hit_id>YDL079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:312951:314748:-1 gene:YDL079C transcript:YDL079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MRK1 description:Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication [Source:SGD;Acc:S000002237]</Hit_def>
  <Hit_accession>YDL079C</Hit_accession>
  <Hit_len>501</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>99.3673</Hsp_bit-score>
      <Hsp_score>246</Hsp_score>
      <Hsp_evalue>5.94089e-22</Hsp_evalue>
      <Hsp_query-from>483</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>164</Hsp_hit-from>
      <Hsp_hit-to>447</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>83</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>42</Hsp_gaps>
      <Hsp_align-len>293</Hsp_align-len>
      <Hsp_qseq>YSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKH-----GKQSDDKVQYLIYQILKGLKYIHS-SGIIHRDLKPGNLAVNEDC-ELKILDFGLAR--HADQEMTGYVVTRWYRAPEVILNWMHYT------------------------QTDMDQLMLILKLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>YPTTEVVGHGSFGVVVTTVIIETNQKVAIKKV---LQDRRYKN---RELETMKMLCHPNTVGLQYYFYEKDEEDEVY-LNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKIMGIPTKDEISGMNPNYEDHV-FPNIKPITLAEI-FKAEDPDTLDLLTKTLKYHPCERLVPLQCLLSSYF</Hsp_hseq>
      <Hsp_midline>Y     VG G++G V +++ + T  KVA+KK+    Q R +     REL  +K + H N +GL   F   D  D+     LV+ +M   L + ++H      +    ++++  YQ+ K L Y+H+   I HRD+KP NL V+      KI DFG A+    DQ    Y+ +R+YRAPE++    +Y+                        ++ +DQL+ I+K+ G P +  +  M+ N    + F    P T   + F       +DLL K L   P +R    + L   +F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>14</Hit_num>
  <Hit_id>YFR014C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:172537:173877:-1 gene:YFR014C transcript:YFR014C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK1 description:Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]</Hit_def>
  <Hit_accession>YFR014C</Hit_accession>
  <Hit_len>446</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>96.6709</Hsp_bit-score>
      <Hsp_score>239</Hsp_score>
      <Hsp_evalue>2.36026e-21</Hsp_evalue>
      <Hsp_query-from>477</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>35</Hsp_hit-from>
      <Hsp_hit-to>299</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>84</Hsp_identity>
      <Hsp_positive>132</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>276</Hsp_align-len>
      <Hsp_qseq>KRYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPF--QSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFM--GTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNL---AVNEDCELKILDFGLARH--ADQEMT-GYVVTRWYRAPEVILNWMHYTQTDMDQLMLILK--LTGTPPQYLVDRMDENVSCLLHFITRG--PGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>KKYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDK------FYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCG----YSAFRA-ERVQDFLDECTTGEYPVKFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAELLEDPWI</Hsp_hseq>
      <Hsp_midline>K+Y     +G+G +G V  + +  TG  VAVK L +     ++V  +  Y EL +L+ + H N++   D F   D       FY++      G    +I+K GK +++    ++ +IL  +KY+HS  I+HRDLKP NL     +++  L + DFG+A+   +D+E+      +  Y APEV+    H    D+  + +I    L G    Y   R  E V   L   T G  P   H   +      A   + K L LDP +RPTA+E L+ P+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>15</Hit_num>
  <Hit_id>YPL153C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:261727:264192:-1 gene:YPL153C transcript:YPL153C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RAD53 description:DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]</Hit_def>
  <Hit_accession>YPL153C</Hit_accession>
  <Hit_len>821</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>97.0561</Hsp_bit-score>
      <Hsp_score>240</Hsp_score>
      <Hsp_evalue>7.52609e-21</Hsp_evalue>
      <Hsp_query-from>501</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>204</Hsp_hit-from>
      <Hsp_hit-to>466</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>86</Hsp_identity>
      <Hsp_positive>128</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>278</Hsp_align-len>
      <Hsp_qseq>VGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKR--AYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFM-GTDLSK-IMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNED--CELKILDFGLARHADQE--MTGYVVTRWYRAPEVILNWMHYTQTD----------------MDQLMLILKLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>VGQGAFATVKKAIERTTGKTFAVKIISK---RKVIGNMDGVTRELEVLQKLNHPRIVRLKGFY------EDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVI-LTGHLP-FSGSTQDQ----LYKQIGRGSYHEGPLKDFRISEEARDFIDSLLQVDPNNRSTAAKALNHPWI</Hsp_hseq>
      <Hsp_midline>VG GA+ TV  +++  TG   AVK + +    +V        REL +L+ + H  ++ L   +      +  + +Y+VM F+ G DL   +  HG   +D  + +  QIL  +KYIHS GI HRDLKP N+ + +D    +KI DFGLA+       M  +  T  Y APEVI         D                M  L+ ++ LTG  P +     D+    L   I RG      L+       A D ++ +L +DP  R TA++AL HP+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>16</Hit_num>
  <Hit_id>YDL101C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:280307:281848:-1 gene:YDL101C transcript:YDL101C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DUN1 description:Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]</Hit_def>
  <Hit_accession>YDL101C</Hit_accession>
  <Hit_len>513</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>93.9745</Hsp_bit-score>
      <Hsp_score>232</Hsp_score>
      <Hsp_evalue>2.75871e-20</Hsp_evalue>
      <Hsp_query-from>501</Hsp_query-from>
      <Hsp_query-to>1265</Hsp_query-to>
      <Hsp_hit-from>206</Hsp_hit-from>
      <Hsp_hit-to>481</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>82</Hsp_identity>
      <Hsp_positive>136</Hsp_positive>
      <Hsp_gaps>53</Hsp_gaps>
      <Hsp_align-len>292</Hsp_align-len>
      <Hsp_qseq>VGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRE-LRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFM--GTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVN-------------------EDCELKILDFGLARH-ADQEMTGYVV-TRWYRAPEVILNWMHYTQTDM--DQLMLILKLTGTPPQYLVDRMDENVSCLLHFITRGPGT--RHWLQ--FTFYGA-------AAIDLLEKMLALDPEQRPTASEALQHPFFS</Hsp_qseq>
      <Hsp_hseq>LGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQK-YLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVILYVCLCGFPP--FSDQL-------------GPPSLKEQILQAKYAFYSPYWDKIDDSVLHLISNLLVLNPDERYNIDEALNHPWFN</Hsp_hseq>
      <Hsp_midline>+G+G Y  V  + +  TG +VAVK  +          + +RE   +L  ++H N++ L+D F    +  Q Q  YLV+  +  G    +I++      D+ + L  Q+L GLKY+H   IIHRD+KP N+ +N                    D ++KI DFGLA+   + + T  +  T  Y APEV+    + ++ D+    ++L + L G PP    D++             GP +     LQ  + FY         + + L+  +L L+P++R    EAL HP+F+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>17</Hit_num>
  <Hit_id>YNL307C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:56446:57573:-1 gene:YNL307C transcript:YNL307C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MCK1 description:Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]</Hit_def>
  <Hit_accession>YNL307C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.5077</Hsp_bit-score>
      <Hsp_score>223</Hsp_score>
      <Hsp_evalue>1.27394e-19</Hsp_evalue>
      <Hsp_query-from>501</Hsp_query-from>
      <Hsp_query-to>1265</Hsp_query-to>
      <Hsp_hit-from>41</Hsp_hit-from>
      <Hsp_hit-to>328</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>87</Hsp_identity>
      <Hsp_positive>127</Hsp_positive>
      <Hsp_gaps>57</Hsp_gaps>
      <Hsp_align-len>300</Hsp_align-len>
      <Hsp_qseq>VGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQ-SRVFAKRAY--RELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMP------------FMGTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVN-EDCELKILDFGLAR--HADQEMTGYVVTRWYRAPEVILNWMHYT------------------------QTDMDQLMLILKLTGTPPQYLVDRMDENVSCLLH---FITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFFS</Hsp_qseq>
      <Hsp_hseq>IGRGAFGTVVQAY--LTQDK---KNWLGPFAIKKVPAHTEYKSRELQILRIADHPNIVKLQYFFTHLSPQDNKVYQHLAMECLPETLQIEINRYVTNKLEMPLKH-------IRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSISYICSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLREIAKLLGPPDKRFIFFSNPAYDGPLFSKPLFSGSSQQRFEKYFGHSGPDGIDLLMKILVYEPQQRLSPRRILAHQFFN</Hsp_hseq>
      <Hsp_midline>+G GA+GTV  +   +T  K   K    PF   +V A   Y  REL++L+   H N++ L   FT     D     +L M             ++   L   +KH       ++   YQI +G+ Y+H  G+ HRD+KP N+ V+ E   LKI DFG A+    +Q    Y+ +R+YRAPE+I+    YT                        Q  + QL  I KL G P +  +   +      L      +     R    F   G   IDLL K+L  +P+QR +    L H FF+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>18</Hit_num>
  <Hit_id>YOL016C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:294777:296120:-1 gene:YOL016C transcript:YOL016C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CMK2 description:Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376]</Hit_def>
  <Hit_accession>YOL016C</Hit_accession>
  <Hit_len>447</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.1225</Hsp_bit-score>
      <Hsp_score>222</Hsp_score>
      <Hsp_evalue>3.01697e-19</Hsp_evalue>
      <Hsp_query-from>498</Hsp_query-from>
      <Hsp_query-to>1265</Hsp_query-to>
      <Hsp_hit-from>52</Hsp_hit-from>
      <Hsp_hit-to>310</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>128</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>273</Hsp_align-len>
      <Hsp_qseq>AVGSGAYGTVCSSMDLVTGSKVAVKKLYRPF--QSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFM--GTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAV---NEDCELKILDFGLARHADQE---MTGYVVTRWYRAPEVILNWMHYTQTDMDQLMLILK--LTGTPPQYLVDRMDENVSCLLHFIT--RGPGTRHWLQFTFYGAAAIDL---LEKMLALDPEQRPTASEALQHPFFS</Hsp_qseq>
      <Hsp_hseq>TLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDK------FYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSP-----FIAESVEGFMEECTASRYPVTFH---MPYWDNISIDVKRFILKALRLNPADRPTATELLDDPWIT</Hsp_hseq>
      <Hsp_midline> +G+G++G V  +  L T   VA+K L +     + V  +  Y EL +L+ + H N++   D F   D       FY+V      G    +I+  GK ++     +I QIL  ++Y+HS  ++HRDLKP N+     +E+  L I DFG+A+    E   +     +  Y APEV+    H    D+  + +I    L G  P      + E+V   +   T  R P T H     ++   +ID+   + K L L+P  RPTA+E L  P+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>19</Hit_num>
  <Hit_id>YOR061W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:441534:442553:1 gene:YOR061W transcript:YOR061W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA2 description:Alpha&apos; catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000005587]</Hit_def>
  <Hit_accession>YOR061W</Hit_accession>
  <Hit_len>339</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>88.5817</Hsp_bit-score>
      <Hsp_score>218</Hsp_score>
      <Hsp_evalue>3.23728e-19</Hsp_evalue>
      <Hsp_query-from>465</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>44</Hsp_hit-from>
      <Hsp_hit-to>334</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>82</Hsp_identity>
      <Hsp_positive>131</Hsp_positive>
      <Hsp_gaps>61</Hsp_gaps>
      <Hsp_align-len>309</Hsp_align-len>
      <Hsp_qseq>WEVPKRYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKH-ENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVN-EDCELKILDFGLAR--HADQEMTGYVVTRWYRAPEVILNWMHYT-------------------------QTDMDQLMLILKLTGT--------------PPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>WGKISNYEIINKIGRGKYSEVFSGRCIVNNQKCVIKVL-KP----VKMKKIYRELKILTNLTGGPNVVGLYDIVQDADSKIPALIFEEIK---NVDFRTLYPTFKLPD--IQYYFTQLLIALDYCHSMGIMHRDVKPQNVMIDPTERKLRLIDWGLAEFYHPGVDYNVRVASRYHKGPELLVNLNQYDYSLDLWSVGCMLAAIVFKKEPFFKGSSNPDQLVKIATVLGTKELLGYLGKYGLHLPSEYDNIMRDFTKKSWTHFITS--------ETKLAVPEVVDLIDNLLRYDHQERLTAKEAMDHKFF</Hsp_hseq>
      <Hsp_midline>W     Y  +  +G G Y  V S   +V   K  +K L +P    V  K+ YREL++L ++    NV+GL D+    D+      F  +      D   +    K  D  +QY   Q+L  L Y HS GI+HRD+KP N+ ++  + +L+++D+GLA   H   +    V +R+++ PE+++N   Y                           ++ DQL+ I  + GT              P +Y     D       HFIT         +        +DL++ +L  D ++R TA EA+ H FF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>20</Hit_num>
  <Hit_id>YPL140C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:287514:289034:-1 gene:YPL140C transcript:YPL140C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK2 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]</Hit_def>
  <Hit_accession>YPL140C</Hit_accession>
  <Hit_len>506</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.5077</Hsp_bit-score>
      <Hsp_score>223</Hsp_score>
      <Hsp_evalue>3.26034e-19</Hsp_evalue>
      <Hsp_query-from>486</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>215</Hsp_hit-from>
      <Hsp_hit-to>481</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>131</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>272</Hsp_align-len>
      <Hsp_qseq>SQLFAVGSGAYGTVCSSMDLVTGSKV-AVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMG------TDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQEMT-GYVVTRWYRAPEVILNWMHYTQTDMDQLML-ILKLTGTPPQYLVDRMDENVS---CLLHFITRGPGTRHWLQFTFYGAAAI-DLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>TTLGILGEGAGGSV-AKCRLKNGKKVFALKTINTMNTDPEYQKQIFRELQFNKSFKSDYIVQYYGMFTD----EQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFGVSGEAVNSLAMTFTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRFPFESDKITQNVAPIELLTMILTFSPQLKDEPELDISWSKTFRSFIDYCLKKDARERPSPRQMLKHPWI</Hsp_hseq>
      <Hsp_midline>+ L  +G GA G+V +   L  G KV A+K +        + K+ +REL+  K  K + ++    +FT     +Q    Y+ M +MG      T  + + + G+ S+  +  +   +L+GL Y+H   +IHRD+KP N+ +NE  E+K+ DFG++  A   +   +  T +Y APE I    +    D+  L L +L++ G    +  D++ +NV+    L   +T  P  +   +     +      ++  L  D  +RP+  + L+HP+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>21</Hit_num>
  <Hit_id>YOR231W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:772601:774127:1 gene:YOR231W transcript:YOR231W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MKK1 description:MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]</Hit_def>
  <Hit_accession>YOR231W</Hit_accession>
  <Hit_len>508</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>90.1225</Hsp_bit-score>
      <Hsp_score>222</Hsp_score>
      <Hsp_evalue>4.64746e-19</Hsp_evalue>
      <Hsp_query-from>480</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>220</Hsp_hit-from>
      <Hsp_hit-to>488</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>132</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>274</Hsp_align-len>
      <Hsp_qseq>RYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRV-FAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMG-TDLSKIMKH-----GKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQEM-TGYVVTRWYRAPEVILNWMHYTQTDMDQLML-ILKLTGTPPQYLVDRMDENVS---CLLHFITRGPGTRHWLQFTFYGAAAI-DLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>RIETLGILGEGAGGSV-SKCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQFNRSFQSEYIVRYYGMFTD----DENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVSGEAVNSLATTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANGKFPCSSEKMAANIAPFELLMWILTFTPELKDEPESNIIWSPSFKSFIDYCLKKDSRERPSPRQMINHPWI</Hsp_hseq>
      <Hsp_midline>R   L  +G GA G+V S   L  GSK+   K+     +   + K+ +REL+  +  + E ++    +FT     D+    Y+ M +MG   L  I K+     G+ S+  +  +   +L+GL Y+H   +IHRD+KP N+ +NE+ ++K+ DFG++  A   + T +  T +Y APE I    +   +D+  L L IL++         ++M  N++    L+  +T  P  +   +     + +    ++  L  D  +RP+  + + HP+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>22</Hit_num>
  <Hit_id>YHL007C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:95118:97937:-1 gene:YHL007C transcript:YHL007C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE20 description:Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]</Hit_def>
  <Hit_accession>YHL007C</Hit_accession>
  <Hit_len>939</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>91.2781</Hsp_bit-score>
      <Hsp_score>225</Hsp_score>
      <Hsp_evalue>5.54279e-19</Hsp_evalue>
      <Hsp_query-from>480</Hsp_query-from>
      <Hsp_query-to>1265</Hsp_query-to>
      <Hsp_hit-from>619</Hsp_hit-from>
      <Hsp_hit-to>872</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>67</Hsp_identity>
      <Hsp_positive>136</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>268</Hsp_align-len>
      <Hsp_qseq>RYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFM-GTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQ---EMTGYVVTRWYRAPEVILNWMHYTQTDMDQL--MLILKLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFFS</Hsp_qseq>
      <Hsp_hseq>KYANLVKIGQGASGGVYTAYEIGTNVSVAIKQMN--LEKQPKKELIINEILVMKGSKHPNIVNFIDSYV------LKGDLWVIMEYMEGGSLTDVVTHCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPP-YL----NETPLRALYLIATN-GTPKLKEPENLSSSLKKFLDWCLCVEPEDRASATELLHDEYIT</Hsp_hseq>
      <Hsp_midline>+Y+ L  +G GA G V ++ ++ T   VA+K++    + +   +    E+ ++K  KH N++  +D +          D +++M +M G  L+ ++ H   ++ ++  +  + L GL+++HS G++HRD+K  N+ ++ + ++K+ DFG     ++   + T  V T ++ APEV+    +  + D+  L  M+I  + G PP YL    +E     L+ I    GT    +     ++    L+  L ++PE R +A+E L   + +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>23</Hit_num>
  <Hit_id>YDR477W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1412373:1414274:1 gene:YDR477W transcript:YDR477W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SNF1 description:AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]</Hit_def>
  <Hit_accession>YDR477W</Hit_accession>
  <Hit_len>633</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>89.3521</Hsp_bit-score>
      <Hsp_score>220</Hsp_score>
      <Hsp_evalue>1.25605e-18</Hsp_evalue>
      <Hsp_query-from>480</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>54</Hsp_hit-from>
      <Hsp_hit-to>306</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>79</Hsp_identity>
      <Hsp_positive>133</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>273</Hsp_align-len>
      <Hsp_qseq>RYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAK-----RAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDL-SKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLAR--HADQEMTGYVVTRWYRAPEVILNWMHY-TQTDMDQLMLILKLTGTPPQYLVDRM---DENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>NYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINK----KVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKD------EIIMVIEYAGNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVM------LCRRLPFDDESIPVLFKNISNGVYT--LPKFLSPGAAG--LIKRMLIVNPLNRISIHEIMQDDWF</Hsp_hseq>
      <Hsp_midline> Y  +  +G G++G V  +    TG KVA+K + +    +V AK     R  RE+  L+ ++H ++I L DV    D      +  +V+ + G +L   I++  K S+ + +    QI+  ++Y H   I+HRDLKP NL ++E   +KI DFGL+        +     +  Y APEVI   ++   + D+    +IL +       L  R+   DE++  L   I+ G  T    +F   GAA   L+++ML ++P  R +  E +Q  +F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>24</Hit_num>
  <Hit_id>YJL095W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:247255:251691:1 gene:YJL095W transcript:YJL095W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BCK1 description:MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]</Hit_def>
  <Hit_accession>YJL095W</Hit_accession>
  <Hit_len>1478</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>89.7373</Hsp_bit-score>
      <Hsp_score>221</Hsp_score>
      <Hsp_evalue>1.8785e-18</Hsp_evalue>
      <Hsp_query-from>501</Hsp_query-from>
      <Hsp_query-to>1259</Hsp_query-to>
      <Hsp_hit-from>1181</Hsp_hit-from>
      <Hsp_hit-to>1439</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>273</Hsp_align-len>
      <Hsp_qseq>VGSGAYGTVCSSMDLVTGSKVAVKKLYRP--------FQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLAR-------HADQEMTGYVVTRWYRAPEVILNWMHYT-QTDMDQLMLIL--KLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAI--DLLEKMLALDPEQRPTASEALQHPF</Hsp_qseq>
      <Hsp_hseq>IGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRS--EVSTLKDLDHLNIVQYLGFENKNNIYSLFLEYVA----GGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTV---FWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLE-----VVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANELLSHPF</Hsp_hseq>
      <Hsp_midline>+G G++G V   +++ TG  +AVK++  P          S V A R+  E+  LK + H N++  +     N+    F ++       G+  S I  +G+  +  +++L  Q+LKGL Y+HS GI+HRD+K  NL +++D   KI DFG++R       ++D  M G V   ++ APE++     Y+ + D+  L  I+     G  P   ++     V   +  I +        + T    + I  + L+    ++PE+RPTA+E L HPF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>25</Hit_num>
  <Hit_id>YPL042C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:473040:474707:-1 gene:YPL042C transcript:YPL042C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSN3 description:Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]</Hit_def>
  <Hit_accession>YPL042C</Hit_accession>
  <Hit_len>555</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>85.8853</Hsp_bit-score>
      <Hsp_score>211</Hsp_score>
      <Hsp_evalue>1.47076e-17</Hsp_evalue>
      <Hsp_query-from>603</Hsp_query-from>
      <Hsp_query-to>1265</Hsp_query-to>
      <Hsp_hit-from>200</Hsp_hit-from>
      <Hsp_hit-to>464</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>125</Hsp_positive>
      <Hsp_gaps>60</Hsp_gaps>
      <Hsp_align-len>273</Hsp_align-len>
      <Hsp_qseq>FAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQSDDK------VQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQEM----TG--YVVTRWYRAPEVILNWMHYTQT-----------------------------------DMDQLMLILKLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAA-----AIDLLEKMLALDPEQRPTASEALQHPFFS</Hsp_qseq>
      <Hsp_hseq>ISQSACREMALCRELHNKHLTTLVEIFLERKCV------HMVYEYAEHDLLQIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDGCVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELIGLQPIFKGEEAKLDSKKTVPFQVNQLQRILEVLGTPDQKIWPYLEKYPE--YDQITKFPKYRDNLATWYHSAGGRDKHALSLLYHLLNYDPIKRIDAFNALEHKYFT</Hsp_hseq>
      <Hsp_midline> ++ A RE+ L + + ++++  LV++F     +      ++V  +   DL +I+      + +      V+ +++Q+L G+ Y+H + ++HRDLKP N+ V  D  +KI D GLAR     +    TG   VVT WYRAPE++L   HYT                                      ++QL  IL++ GTP Q +   +++        IT+ P  R  L   ++ A      A+ LL  +L  DP +R  A  AL+H +F+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>26</Hit_num>
  <Hit_id>YCL024W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:79162:82275:1 gene:YCL024W transcript:YCL024W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KCC4 description:Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]</Hit_def>
  <Hit_accession>YCL024W</Hit_accession>
  <Hit_len>1037</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>84.7297</Hsp_bit-score>
      <Hsp_score>208</Hsp_score>
      <Hsp_evalue>4.83727e-17</Hsp_evalue>
      <Hsp_query-from>498</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>26</Hsp_hit-from>
      <Hsp_hit-to>285</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>80</Hsp_identity>
      <Hsp_positive>125</Hsp_positive>
      <Hsp_gaps>39</Hsp_gaps>
      <Hsp_align-len>277</Hsp_align-len>
      <Hsp_qseq>AVGSGAYGTVCSSMDLVTGSKVAVKKLYRPF---------QSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFM--GTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLAR-HADQEMTGYVV-TRWYRAPEVILNWMHYTQTDMD----QLMLILKLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQF-----TFYGAAAIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>TLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNL------YLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIV-SGLPYEGFASDVWSCGVILFALLTGRLP---FDEENGNVRDLLLKVQKG-------QFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLL</Hsp_hseq>
      <Hsp_midline> +G G+ G V  +    TG + AVK + +              V      RE+ ++K + H NV+ L DV+  N+ L      YL++ +   G   + ++ HG   + +      QI+ G+ Y H+ GI+HRDLKP NL ++    +KI DFG+A    D ++      +  Y APE++ + + Y     D     ++L   LTG  P    D  + NV  LL  + +G       QF     T     A DL+ K+L +DP QR    + L HP  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>27</Hit_num>
  <Hit_id>YJL106W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:221390:223327:1 gene:YJL106W transcript:YJL106W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IME2 description:Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]</Hit_def>
  <Hit_accession>YJL106W</Hit_accession>
  <Hit_len>645</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>84.3445</Hsp_bit-score>
      <Hsp_score>207</Hsp_score>
      <Hsp_evalue>5.63721e-17</Hsp_evalue>
      <Hsp_query-from>549</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>90</Hsp_hit-from>
      <Hsp_hit-to>386</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>135</Hsp_positive>
      <Hsp_gaps>89</Hsp_gaps>
      <Hsp_align-len>312</Hsp_align-len>
      <Hsp_qseq>TGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHM----KHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQ---SDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCE-----------------LKILDFGLARHADQEM--TGYVVTRWYRAPEVILNWMHYTQ------------------------TDMDQLMLILKLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHW-----------LQFTFYGA-------------AAIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>TQGVVAIKTM----MTKLHTLQDYTRVREIKFILAIPANDHLIQIFEVFIDSENYQ----LHIVMECMEQNLYQMMKHRRRRVFSIPSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVENKNPYTAYVSTRWYRSPEILLRSGYYSKPLDIWAFGCVAVEVTVFRALFPGANEIDQIWKILEVLGTP----IKRSD---FVNTNHITAPPPGGFWDDASNLVHKLNLKLPYVEGSSLDHLLSSSQLSDLSEVVKKCLRWDPNERATAQELCEMPFF</Hsp_hseq>
      <Hsp_midline>T   VA+K +     +++   + Y  +R +K +     ++++I + +VF  ++        ++VM  M  +L ++MKH ++   S   ++ ++ QIL GLK+IH     HRDLKP N+ +    +                 +K+ DFGLARH + +   T YV TRWYR+PE++L   +Y++                         ++DQ+  IL++ GTP    + R D       + IT  P    W           L+  +                   ++++K L  DP +R TA E  + PFF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>28</Hit_num>
  <Hit_id>YCR073C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:242588:246583:-1 gene:YCR073C transcript:YCR073C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK22 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]</Hit_def>
  <Hit_accession>YCR073C</Hit_accession>
  <Hit_len>1331</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>84.7297</Hsp_bit-score>
      <Hsp_score>208</Hsp_score>
      <Hsp_evalue>5.98313e-17</Hsp_evalue>
      <Hsp_query-from>471</Hsp_query-from>
      <Hsp_query-to>1259</Hsp_query-to>
      <Hsp_hit-from>1030</Hsp_hit-from>
      <Hsp_hit-to>1309</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>132</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>294</Hsp_align-len>
      <Hsp_qseq>VPKRYSQLFAVGSGAYGTVCSSMDLVTGSKVAVK--KLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQSDDKV-QYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLAR----------------------HADQEMTGYVVTRWYRAPEVILNWMHYTQTDMDQL----MLILKL-TGTPPQYLVDRMDENVSCLLHFIT-RGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPF</Hsp_qseq>
      <Hsp_hseq>VSMRWQKRSFIGGGTFGQVYSAINLENGEILAVKEIKIHDTTTMKKIFPLIKEEMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEY-----CEGGSLASLLDHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMG---TPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPW---SNLDNEWAIMYHVAAGRIPQLPNRDEMTAAGRA---FLERCLVQDPTMRATAVELLIDPW</Hsp_hseq>
      <Hsp_midline>V  R+ +   +G G +G V S+++L  G  +AVK  K++     +        E+ +L+ + H N++    V    D ++ F ++       G  L+ ++ HG+  D+ V Q   +++L+GL Y+H SG++HRD+KP N+ ++ +  +K +DFG AR                       +  EM G   T  Y APE I       +   D +     ++L++ TG  P      +D   + + H    R P   +  + T  G A    LE+ L  DP  R TA E L  P+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>29</Hit_num>
  <Hit_id>YNR031C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:680694:685433:-1 gene:YNR031C transcript:YNR031C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SSK2 description:MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]</Hit_def>
  <Hit_accession>YNR031C</Hit_accession>
  <Hit_len>1579</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>83.9593</Hsp_bit-score>
      <Hsp_score>206</Hsp_score>
      <Hsp_evalue>1.20421e-16</Hsp_evalue>
      <Hsp_query-from>420</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>1245</Hsp_hit-from>
      <Hsp_hit-to>1558</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>79</Hsp_identity>
      <Hsp_positive>144</Hsp_positive>
      <Hsp_gaps>63</Hsp_gaps>
      <Hsp_align-len>329</Hsp_align-len>
      <Hsp_qseq>SSRKGFYRIEINKMVWEVPKRYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAY----RELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQSDDKV-QYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLAR----------------HADQE-------------------MTGYVVTRWYRAPEVILNWMHYTQTDMDQL-----MLILKLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTF---YGAAAIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>SDKGNKYLVSLASSISNVSMRWQKRNFIGGGTFGRVYSAVDLDNGEILAVKEIN--IQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEY-----CEGGSLAALLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPWANLD----NEWAIMYHVAAG----HTPQFPTKDEVSSAGMKFLERCLIQNPSKRASAVELLMDPWI</Hsp_hseq>
      <Hsp_midline>S +   Y + +   +  V  R+ +   +G G +G V S++DL  G  +AVK++    Q     ++ +     E+ +L+ + H N++    V    D ++ F ++       G  L+ +++HG+  D+ V Q    Q+L+GL Y+H SGI+HRD+KP N+ ++ +  +K +DFG A+                +AD E                   +   + T  Y APE I       +   D +     +++  +TG  P   +D    N   +++ +  G    H  QF       +A +  LE+ L  +P +R +A E L  P+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>30</Hit_num>
  <Hit_id>YIL035C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IX:287790:288908:-1 gene:YIL035C transcript:YIL035C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CKA1 description:Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000001297]</Hit_def>
  <Hit_accession>YIL035C</Hit_accession>
  <Hit_len>372</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.8777</Hsp_bit-score>
      <Hsp_score>198</Hsp_score>
      <Hsp_evalue>2.00333e-16</Hsp_evalue>
      <Hsp_query-from>549</Hsp_query-from>
      <Hsp_query-to>1265</Hsp_query-to>
      <Hsp_hit-from>108</Hsp_hit-from>
      <Hsp_hit-to>364</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>66</Hsp_gaps>
      <Hsp_align-len>281</Hsp_align-len>
      <Hsp_qseq>TGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVN-EDCELKILDFGLAR--HADQEMTGYVVTRWYRAPEVILNWMHYT-------------------------QTDMDQLMLILKLTGTP-------------PQYLVDRMDENVSCLLH-FITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFFS</Hsp_qseq>
      <Hsp_hseq>TNQKEDVLKFIRPY---IFDQ---------PHNGHANIIHLFDII--KDPISKTPA--LVFEYVDNVDFRIL-YPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLLKYEITLPREFYD-MDQYIRKPWHRFI--NDGNKHLSG----NDEIIDLIDNLLRYDHQERLTAKEAMGHPWFA</Hsp_hseq>
      <Hsp_midline>T  K  V K  RP+   +F +          H  H N+I L D+    D + +     LV  ++     +I+ + K +D ++++ ++++LK L Y HS GI+HRD+KP N+ ++ ++ +L+++D+GLA   H + E    V +R+++ PE+++++  Y                           ++ DQL+ I+K+ GT              P+   D MD+ +    H FI    G +H           IDL++ +L  D ++R TA EA+ HP+F+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>31</Hit_num>
  <Hit_id>YGL179C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:163409:165091:-1 gene:YGL179C transcript:YGL179C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TOS3 description:Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003147]</Hit_def>
  <Hit_accession>YGL179C</Hit_accession>
  <Hit_len>560</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.4925</Hsp_bit-score>
      <Hsp_score>197</Hsp_score>
      <Hsp_evalue>7.06548e-16</Hsp_evalue>
      <Hsp_query-from>492</Hsp_query-from>
      <Hsp_query-to>929</Hsp_query-to>
      <Hsp_hit-from>53</Hsp_hit-from>
      <Hsp_hit-to>211</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>82</Hsp_positive>
      <Hsp_gaps>21</Hsp_gaps>
      <Hsp_align-len>163</Hsp_align-len>
      <Hsp_qseq>LFAVGSGAYGTVCSSMDLVTGSKVAVKKLYR-------PFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQSDDKV----------QYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLA</Hsp_qseq>
      <Hsp_hseq>LATLGNGQYGKVKLARDLGTGALVAIKILNRFEKRSGYSLQLKVENPRVNQEIEVMKRCHHENVVELYEIL--NDP--ESTKVYLVLEYCSRGPVKWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVA</Hsp_hseq>
      <Hsp_midline>L  +G+G YG V  + DL TG+ VA+K L R         Q +V   R  +E+ ++K   HENV+ L ++   ND   +    YLV+ +      K     K     V          + ++  ++ GL+Y+HS GI HRD+KP NL ++ +  +KI DFG+A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>32</Hit_num>
  <Hit_id>YDR507C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1462358:1465786:-1 gene:YDR507C transcript:YDR507C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GIN4 description:Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]</Hit_def>
  <Hit_accession>YDR507C</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.8777</Hsp_bit-score>
      <Hsp_score>198</Hsp_score>
      <Hsp_evalue>7.73374e-16</Hsp_evalue>
      <Hsp_query-from>498</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>24</Hsp_hit-from>
      <Hsp_hit-to>289</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>79</Hsp_identity>
      <Hsp_positive>130</Hsp_positive>
      <Hsp_gaps>51</Hsp_gaps>
      <Hsp_align-len>286</Hsp_align-len>
      <Hsp_qseq>AVGSGAYGTVCSSMDLVTGSKVAVKKLYRP-FQSRVFAKRAY--------------RELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFM--GTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQEMTGYVV-----TRWYRAPEVILNWMHYTQTDMD----QLMLILKLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTF-----YGAAAIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>TLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETN------TDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAAL---ETEGKLLETSCGSPHYAAPEIV-SGIPYQGFASDVWSCGVILFALLTGRLP---FDEEDGNIRTLLLKVQKG-------EFEMPSDDEISREAQDLIRKILTVDPERRIKTRDILKHPLL</Hsp_hseq>
      <Hsp_midline> +G G+ G V  + +  TG + AVK + +  F +   +  +               RE+ ++K + H NV+ L DV+  N       D YLV+ +   G   + +++ G   + +      QI+ G+ Y H+ GI+HRDLKP NL ++    +KI DFG+A     E  G ++     +  Y APE++ + + Y     D     ++L   LTG  P    D  D N+  LL  + +G       +F           A DL+ K+L +DPE+R    + L+HP  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>33</Hit_num>
  <Hit_id>YOL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:78352:79479:-1 gene:YOL128C transcript:YOL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YGK3 description:Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005488]</Hit_def>
  <Hit_accession>YOL128C</Hit_accession>
  <Hit_len>375</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.5666</Hsp_bit-score>
      <Hsp_score>192</Hsp_score>
      <Hsp_evalue>1.06751e-15</Hsp_evalue>
      <Hsp_query-from>501</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>47</Hsp_hit-from>
      <Hsp_hit-to>329</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>128</Hsp_positive>
      <Hsp_gaps>49</Hsp_gaps>
      <Hsp_align-len>293</Hsp_align-len>
      <Hsp_qseq>VGSGAYGTVCSSMDLVTGS-----KVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFY---LVMPFMGTDLSKIMKH-----GKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCEL-KILDFGLARHADQ--EMTGYVVTRWYRAPEVILNWMHY-TQTDMDQLMLIL-KLTGTPPQYLVDRMDENVSCLLHFITRGPGTR--------------------HWL-QFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>IGHGSFGTVTQSI-LSSNSIEWLGPYAIKRVVKS------PKVQSLELEILQNIRHPNLVTLEFFFESHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGIAKVCDFGSAQRLDDNTELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPLFKGDSANSQLEEIAKLLGRFPKSSIKNSQELQDSLNDQKFKKFMHWFPSIEFFD---VEFLLKVLTYDATERCDARQLMAHEFF</Hsp_hseq>
      <Hsp_midline>+G G++GTV  S+ L + S       A+K++ +        K    EL +L++++H N++ L   F  + T       Y    VM ++   LS  +        K     ++   +QIL+ L  +HS  I H DLKP N+ +     + K+ DFG A+  D   E+  Y  +R+YRAPE++LN   Y TQ D+  L  I+ ++    P +  D  +  +  +   + R P +                     HW     F+    ++ L K+L  D  +R  A + + H FF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>34</Hit_num>
  <Hit_id>YAR019C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:172211:175135:-1 gene:YAR019C transcript:YAR019C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC15 description:Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]</Hit_def>
  <Hit_accession>YAR019C</Hit_accession>
  <Hit_len>974</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.1073</Hsp_bit-score>
      <Hsp_score>196</Hsp_score>
      <Hsp_evalue>1.24527e-15</Hsp_evalue>
      <Hsp_query-from>498</Hsp_query-from>
      <Hsp_query-to>1253</Hsp_query-to>
      <Hsp_hit-from>30</Hsp_hit-from>
      <Hsp_hit-to>269</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>122</Hsp_positive>
      <Hsp_gaps>22</Hsp_gaps>
      <Hsp_align-len>257</Hsp_align-len>
      <Hsp_qseq>AVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGT-DLSKIMKHGKQ--SDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQEMTGYVVTRWYRAPEVILNWMHYTQTDMDQL--MLILKLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQH</Hsp_qseq>
      <Hsp_hseq>VIGRGSYGVVYKAINKHTDQVVAIKEVV--YENDEELNDIMAEISLLKNLNHNNIVKY------HGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSALTLAGTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNPPYH--NLTDANIYYAVENDTYYPPSS-------FSEPLKDFLSKCFVKNMYKRPTADQLLKH</Hsp_hseq>
      <Hsp_midline> +G G+YG V  +++  T   VA+K++   +++         E+ LLK++ H N++        +  + +  + Y+++ +     L +++       S+++ +  + Q L GLKY+H  G+IHRD+K  N+ ++ D  +K+ DFG++   +        T  + APE++ N    T +D+  L   ++  LT  PP +  +  D N+   +   T  P +        +     D L K    +  +RPTA + L+H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>35</Hit_num>
  <Hit_id>YMR001C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:269019:271136:-1 gene:YMR001C transcript:YMR001C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC5 description:Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]</Hit_def>
  <Hit_accession>YMR001C</Hit_accession>
  <Hit_len>705</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.7221</Hsp_bit-score>
      <Hsp_score>195</Hsp_score>
      <Hsp_evalue>1.31774e-15</Hsp_evalue>
      <Hsp_query-from>477</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>80</Hsp_hit-from>
      <Hsp_hit-to>337</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>130</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>278</Hsp_align-len>
      <Hsp_qseq>KRYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRP-FQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQ-SDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLAR-HADQEMTGYVV--TRWYRAPEVIL--NWMHYTQTDMDQL--MLILKLTGTPP--QYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAID-----LLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>KDYHRGHFLGEGGFAR-CFQIKDDSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNV-----YILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKC--------------RDFSFPRDKPISDEGKILIRDILSLDPIERPSLTEIMDYVWF</Hsp_hseq>
      <Hsp_midline>K Y +   +G G +   C  +   +G   A K + +   +S    K+   E+++ K M H N++  +D F  +  +     + L+       L +++K  K  ++ +V++   QI   +KY+HS  +IHRDLK GN+  + +  LKI DFGLA   A++    Y +  T  Y APEV++  +  H  + D+  L  ML   L G PP     V+ + E + C                F+F     I      L+  +L+LDP +RP+ +E + + +F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>36</Hit_num>
  <Hit_id>YOR267C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:822588:824867:-1 gene:YOR267C transcript:YOR267C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HRK1 description:Protein kinase; implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005793]</Hit_def>
  <Hit_accession>YOR267C</Hit_accession>
  <Hit_len>759</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>80.1073</Hsp_bit-score>
      <Hsp_score>196</Hsp_score>
      <Hsp_evalue>1.33284e-15</Hsp_evalue>
      <Hsp_query-from>501</Hsp_query-from>
      <Hsp_query-to>1013</Hsp_query-to>
      <Hsp_hit-from>221</Hsp_hit-from>
      <Hsp_hit-to>397</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>61</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>182</Hsp_align-len>
      <Hsp_qseq>VGSGAYGTVCSSMDLVTGSKVAVKKLY--RPFQS-RVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQD-FYLVMPFMGTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLA---RHADQE----MTGYVVTRWYRAPEVILNWMHY</Hsp_qseq>
      <Hsp_hseq>LGSGAGGSVKVLVRPTDGATFAVKEFRPRKPNESVKEYAKKCTAEFCIGSTLHHPNVIETVDVFS-----DSKQNKYYEVMEYCPIDFFAVVMTGKMSRGEINCCLKQLTEGVKYLHSMGLAHRDLKLDNCVMTSQGILKLIDFGSAVVFRYPFEDGVTMAHGIVGSDPYLAPEVITSTKSY</Hsp_hseq>
      <Hsp_midline>+GSGA G+V   +    G+  AVK+    +P +S + +AK+   E  +   + H NVI  VDVF+     D  Q+ +Y VM +   D   ++  GK S  ++   + Q+ +G+KY+HS G+ HRDLK  N  +     LK++DFG A   R+  ++      G V +  Y APEVI +   Y</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>37</Hit_num>
  <Hit_id>YKL101W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:248920:253476:1 gene:YKL101W transcript:YKL101W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:HSL1 description:Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]</Hit_def>
  <Hit_accession>YKL101W</Hit_accession>
  <Hit_len>1518</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>79.7221</Hsp_bit-score>
      <Hsp_score>195</Hsp_score>
      <Hsp_evalue>2.11446e-15</Hsp_evalue>
      <Hsp_query-from>471</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>112</Hsp_hit-from>
      <Hsp_hit-to>369</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>130</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>273</Hsp_align-len>
      <Hsp_qseq>VPKRYSQLFAVGSGAY-GTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFM--GTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVN-EDCELKILDFGLA--RHADQEMTGYVVTRWYRAPEVILNW-MHYTQTDM--DQLMLILKLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>VPKKKAFVHCSNNGTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVW------ENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFN-----DDNIKKLLLKVQSG----KYQMPSNLSSEARDLISKILVIDPEKRITTQEILKHPLI</Hsp_hseq>
      <Hsp_midline>VPK+ + +    +G    +  SSM     S  ++        S+       RE+ ++K + H NV+ L +V+      +   + YLV+ ++  G     ++  GK  + +  +   QI++G+ Y HS  I HRDLKP NL ++ ++  +KI DFG+A     ++ +     +  Y +PE+++    H   +D+    ++L   LTG  P       D+N+  LL  +  G     +   +   + A DL+ K+L +DPE+R T  E L+HP  </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>38</Hit_num>
  <Hit_id>YNL298W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:68915:71443:1 gene:YNL298W transcript:YNL298W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CLA4 description:Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]</Hit_def>
  <Hit_accession>YNL298W</Hit_accession>
  <Hit_len>842</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>78.9518</Hsp_bit-score>
      <Hsp_score>193</Hsp_score>
      <Hsp_evalue>2.5663e-15</Hsp_evalue>
      <Hsp_query-from>486</Hsp_query-from>
      <Hsp_query-to>1265</Hsp_query-to>
      <Hsp_hit-from>543</Hsp_hit-from>
      <Hsp_hit-to>826</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>81</Hsp_identity>
      <Hsp_positive>137</Hsp_positive>
      <Hsp_gaps>52</Hsp_gaps>
      <Hsp_align-len>298</Hsp_align-len>
      <Hsp_qseq>SQLFAV----GSGAYGTV-----------CSSMDLVT--------GSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFM-GTDLSKIMKHGKQSDD--------KVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGL-ARHADQ--EMTGYVVTRWYRAPEVILNWMHYTQTDMDQL--MLILKLTGTPPQYLVDRMDENVSCLLHFITRG-PGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFFS</Hsp_qseq>
      <Hsp_hseq>SQCFKVIEKAGQGASGSVYLAERTHIPTESNMIELINNDIDEPHVGDKVAIKQMVLSKQPR--KELIVNEILVMKDSRHKNIVNFLEAYLRTD-----DDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPP-YL---NEDPLKALYLIATNGTPKLKHPESLSL---EIKRFLSVCLCVDVRYRASTEELLHHGFFN</Hsp_hseq>
      <Hsp_midline>SQ F V    G GA G+V            + ++L+         G KVA+K++    Q R   +    E+ ++K  +H+N++  ++ +   D      D ++VM FM G  L+ I+++   +D+        ++ Y++ +  +GLK++H   IIHRD+K  N+ ++    +KI DFG  AR  D+  +    V T ++ APEV+    +  + D+  L  M I  L G PP YL    ++ +  L    T G P  +H    +         L   L +D   R +  E L H FF+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>39</Hit_num>
  <Hit_id>YDR466W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1395121:1397817:1 gene:YDR466W transcript:YDR466W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH3 description:Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant [Source:SGD;Acc:S000002874]</Hit_def>
  <Hit_accession>YDR466W</Hit_accession>
  <Hit_len>898</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>76.2554</Hsp_bit-score>
      <Hsp_score>186</Hsp_score>
      <Hsp_evalue>1.78237e-14</Hsp_evalue>
      <Hsp_query-from>501</Hsp_query-from>
      <Hsp_query-to>1265</Hsp_query-to>
      <Hsp_hit-from>17</Hsp_hit-from>
      <Hsp_hit-to>294</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>77</Hsp_identity>
      <Hsp_positive>125</Hsp_positive>
      <Hsp_gaps>37</Hsp_gaps>
      <Hsp_align-len>285</Hsp_align-len>
      <Hsp_qseq>VGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAY-----RELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFM--GTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQEMTG--------------------YVVTRWYRAPEVIL-NWMHYTQTDMDQL--MLILKLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFFS</Hsp_qseq>
      <Hsp_hseq>LGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQKHHAGIIKLYYTFHDEENL------YFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQCGYG-SDIWALGCMIYQFVQGQPPFRGENELKTFEKIVALDYPWGPNNRINNSTSPINPLVINLVQKILVIEVNERISLEQIKRHPYFS</Hsp_hseq>
      <Hsp_midline>+G G+Y TV  ++D  + +K+   K+         AK  Y       + LL    H  +I L   F   + L      Y V+ F   G  LS + K G  +D   ++   Q++  L++IHS GIIHRDLKP N+ ++ D  L I DFG A   D  ++G                    +V T  Y +PE++L N   Y  +D+  L  M+   + G PP    + +      +      GP  R     +      I+L++K+L ++  +R +  +  +HP+FS</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>40</Hit_num>
  <Hit_id>YDR122W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:694700:697894:1 gene:YDR122W transcript:YDR122W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN1 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]</Hit_def>
  <Hit_accession>YDR122W</Hit_accession>
  <Hit_len>1064</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>75.485</Hsp_bit-score>
      <Hsp_score>184</Hsp_score>
      <Hsp_evalue>4.15582e-14</Hsp_evalue>
      <Hsp_query-from>609</Hsp_query-from>
      <Hsp_query-to>1253</Hsp_query-to>
      <Hsp_hit-from>189</Hsp_hit-from>
      <Hsp_hit-to>395</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>224</Hsp_align-len>
      <Hsp_qseq>KRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFM--GTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHAD--QEMTGYVVTRWYRAPEVILNWMHYTQTDMD----QLMLILKLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFY-GAAAIDLLEKMLALDPEQRPTASEALQH</Hsp_qseq>
      <Hsp_hseq>KRTIREASLGQILYHPHICRLFEMCTLSN------HFYMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIYDSRKQLHTFCGSLYFAAPE-LLKANPYTGPEVDVWSFGVVLFVLVCGKVP---FD--DENSSVLHEKIKQG-----KVEYPQHLSIEVISLLSKMLVVDPKRRATLKQVVEH</Hsp_hseq>
      <Hsp_midline>KR  RE  L + + H ++  L ++ T ++       FY++  ++  G  L  I++HG   + + +     I   L Y+H++ I+HRDLK  N+ +++  E+KI+DFGL+   D  +++  +  + ++ APE +L    YT  ++D     ++L + + G  P    D  DEN S L   I +G      +++  +     I LL KML +DP++R T  + ++H</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>41</Hit_num>
  <Hit_id>YDR523C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1485566:1487038:-1 gene:YDR523C transcript:YDR523C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SPS1 description:Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]</Hit_def>
  <Hit_accession>YDR523C</Hit_accession>
  <Hit_len>490</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.9442</Hsp_bit-score>
      <Hsp_score>180</Hsp_score>
      <Hsp_evalue>5.73434e-14</Hsp_evalue>
      <Hsp_query-from>477</Hsp_query-from>
      <Hsp_query-to>1259</Hsp_query-to>
      <Hsp_hit-from>16</Hsp_hit-from>
      <Hsp_hit-to>271</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>118</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>271</Hsp_align-len>
      <Hsp_qseq>KRYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMG----TDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQEMT--GYVVTRWYRAPEVILNWMHYTQTDMDQLMLILK----LTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPF</Hsp_qseq>
      <Hsp_hseq>KLYSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLA-QEIFFLAELKSPLITNYIA------TMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPPLSKYDPM----KVMTNLPKRKPPK---LQGPFSDAAK-DFVAGCLVKTPADRPSAYNLLSFEF</Hsp_hseq>
      <Hsp_midline>K YS    +G G +G V  ++D VT   VA+K +            A +E+  L  +K   +   +       T+ +    ++VM + G    +DL K        ++KV ++I+++  GLKY+H    IHRD+K  N+ +NE+  +K+ DFG++ H    +    +V T ++ APEV+   +       D   L +     L G PP    D M      + +   R P     LQ  F  AA  D +   L   P  RP+A   L   F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>42</Hit_num>
  <Hit_id>YLR096W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:332590:336033:1 gene:YLR096W transcript:YLR096W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN2 description:Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086]</Hit_def>
  <Hit_accession>YLR096W</Hit_accession>
  <Hit_len>1147</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>73.9442</Hsp_bit-score>
      <Hsp_score>180</Hsp_score>
      <Hsp_evalue>1.14504e-13</Hsp_evalue>
      <Hsp_query-from>609</Hsp_query-from>
      <Hsp_query-to>1265</Hsp_query-to>
      <Hsp_hit-from>168</Hsp_hit-from>
      <Hsp_hit-to>378</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>62</Hsp_identity>
      <Hsp_positive>115</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>228</Hsp_align-len>
      <Hsp_qseq>KRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFM--GTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHAD--QEMTGYVVTRWYRAPEVILNWMHYTQTDMD----QLMLILKLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFY-GAAAIDLLEKMLALDPEQRPTASEALQHPFFS</Hsp_qseq>
      <Hsp_hseq>KRTVREASLGQILYHPHICRLFEMCTMSN------HFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYRKQLHTFCGSLYFAAPE-LLKAQPYTGPEVDIWSFGIVLYVLVCGKVP---FD--DENSSILHEKIKKG-----KVDYPSHLSIEVISLLTRMIVVDPLRRATLKNVVEHPWMN</Hsp_hseq>
      <Hsp_midline>KR  RE  L + + H ++  L ++ T ++       FY++  ++  G  L  I++HG   +   +     I   L+Y+H++ I+HRDLK  N+ ++   E+KI+DFGL+   D  +++  +  + ++ APE +L    YT  ++D     ++L + + G  P    D  DEN S L   I +G      + +  +     I LL +M+ +DP +R T    ++HP+ +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>43</Hit_num>
  <Hit_id>YBR274W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:749594:751177:1 gene:YBR274W transcript:YBR274W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CHK1 description:Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]</Hit_def>
  <Hit_accession>YBR274W</Hit_accession>
  <Hit_len>527</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.4034</Hsp_bit-score>
      <Hsp_score>176</Hsp_score>
      <Hsp_evalue>2.23048e-13</Hsp_evalue>
      <Hsp_query-from>498</Hsp_query-from>
      <Hsp_query-to>1259</Hsp_query-to>
      <Hsp_hit-from>20</Hsp_hit-from>
      <Hsp_hit-to>280</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>120</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>269</Hsp_align-len>
      <Hsp_qseq>AVGSGAYGTVCSS-MDLVTGSKVAVKKLYRPFQSR--VFAKRAYRELRL-LKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIH-SSGIIHRDLKPGNLAVNEDCELKILDFGLA---RHADQEMTGYVVTRW---YRAPEVILNWMHYTQTDMD----QLMLILKLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPF</Hsp_qseq>
      <Hsp_hseq>TVGQGAFACVKNAHLQMDPSIILAVKFIHVPTCKKMGLSDKDITKEVVLQSKCSKHPNVLRLIDC----NVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQTPWELPSLENEDFV----FFIENDGNLNWGPWSKIEFTHLNLLRKILQPDPNKRVTLKALKLHPW</Hsp_hseq>
      <Hsp_midline> VG GA+  V ++ + +     +AVK ++ P   +  +  K   +E+ L  K  KH NV+ L+D     +   ++    L M   G    KI        D  Q+   Q++  + Y+H   G+ HRD+KP N+ ++++  LK+ DFGLA   R  D  +   +  R    Y APEV+ +   Y     D     ++L + LTG  P  L    +E+      F     G  +W  ++      ++LL K+L  DP +R T      HP+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>44</Hit_num>
  <Hit_id>YJL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:147967:150390:-1 gene:YJL141C transcript:YJL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YAK1 description:Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]</Hit_def>
  <Hit_accession>YJL141C</Hit_accession>
  <Hit_len>807</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>72.0182</Hsp_bit-score>
      <Hsp_score>175</Hsp_score>
      <Hsp_evalue>3.81947e-13</Hsp_evalue>
      <Hsp_query-from>468</Hsp_query-from>
      <Hsp_query-to>1085</Hsp_query-to>
      <Hsp_hit-from>364</Hsp_hit-from>
      <Hsp_hit-to>595</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>108</Hsp_positive>
      <Hsp_gaps>44</Hsp_gaps>
      <Hsp_align-len>241</Hsp_align-len>
      <Hsp_qseq>EVPKRYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRV-FAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFY------LVMPFMGTDLSKIMKHGKQSDDKVQYL---IYQILKGLKYIHSSGIIHRDLKPGN--LAVNEDCELKILDFGLARHADQEMTGYVVTRWYRAPEVILNWMHYTQTDM-----------------------DQLMLILKLTGTPPQYLVD</Hsp_qseq>
      <Hsp_hseq>EQNRKYLVLDILGQGTFGQVVKCQNLLTKEILAVKVV----KSRTEYLTQSITEAKILELLNQK-----IDPTNKHHFLRMYDSFVHKNHLCLVFELLSNNLYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPELKIIDFGSSCEEARTVYTYIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAELFLGIPIFPGASEYNQLTRIIDTLGYPPSWMID</Hsp_hseq>
      <Hsp_midline>E  ++Y  L  +G G +G V    +L+T   +AVK +    +SR  +  ++  E ++L+ +  +     +D    +  L  +  F       LV   +  +L +++K  K     +Q +     QIL  L  +  S +IH DLKP N  L   +  ELKI+DFG +    + +  Y+ +R+YRAPE+IL   + T  DM                       +QL  I+   G PP +++D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>45</Hit_num>
  <Hit_id>YMR104C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIII:473420:475453:-1 gene:YMR104C transcript:YMR104C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK2 description:Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]</Hit_def>
  <Hit_accession>YMR104C</Hit_accession>
  <Hit_len>677</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.8626</Hsp_bit-score>
      <Hsp_score>172</Hsp_score>
      <Hsp_evalue>7.64315e-13</Hsp_evalue>
      <Hsp_query-from>492</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>347</Hsp_hit-from>
      <Hsp_hit-to>599</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>76</Hsp_identity>
      <Hsp_positive>122</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>268</Hsp_align-len>
      <Hsp_qseq>LFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPF-QSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFM-GTDLSKIMKH-GKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLAR--HADQEMTG-YVVTRWYRAPEVILNWMHYTQTDMDQLMLIL--KLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQR---PTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>LKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKL------YLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYY-----DENVPVMYKKILQQP----LLFPDGFDPAAKDLLIGLLSRDPSRRLGVNGTDEIRNHPFF</Hsp_hseq>
      <Hsp_midline>L  +G G++G V       T    A+K L + +  S+        E  +L  +    ++ L   F   + L      YLV+ F+ G +L   ++H G+ S  + ++ I ++L  L  +H   +I+RDLKP N+ ++    + + DFGL +    D + T  +  T  Y APE++L   +    D   L ++L   +TG PP Y     DENV  +   I + P     L    +  AA DLL  +L+ DP +R       E   HPFF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>46</Hit_num>
  <Hit_id>YOL113W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:104326:106293:1 gene:YOL113W transcript:YOL113W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SKM1 description:Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]</Hit_def>
  <Hit_accession>YOL113W</Hit_accession>
  <Hit_len>655</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>1.26673e-12</Hsp_evalue>
      <Hsp_query-from>474</Hsp_query-from>
      <Hsp_query-to>1265</Hsp_query-to>
      <Hsp_hit-from>356</Hsp_hit-from>
      <Hsp_hit-to>640</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>51</Hsp_gaps>
      <Hsp_align-len>300</Hsp_align-len>
      <Hsp_qseq>PKRYSQLF-AVGSGAYGTVCSSMDL-----------------VTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFM-GTDLSKIMKHGKQSD----------DKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQEMTG---YVVTRWYRAPEVILNWMHYTQTDMDQL--MLILKLTGTPPQYLVDRMDENVSCLLHFITRG--PGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFFS</Hsp_qseq>
      <Hsp_hseq>PRPYFQLVEKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQPK--KQLIMNELLVMNDSRQENIVNFLEAYIIDD-----EELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPP-YL----NEDPLKALYLIANNGSPKLRHPESVS---KQTKQFLDACLQVNVESRASVRKLLTFEFLS</Hsp_hseq>
      <Hsp_midline>P+ Y QL    G GA G V  S  +                 V G +VA+K++    Q +   +    EL ++   + EN++  ++ +  +D     ++ +++M +M G  L+ I+    +S+          +++ Y++ +  +GLK++H+  IIHRD+K  N+ +N    +KI DFG      ++ +     V T ++ APE++    +  + D+  L  MLI  + G PP YL    +E+    L+ I     P  RH    +         L+  L ++ E R +  + L   F S</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>47</Hit_num>
  <Hit_id>YPL141C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:283464:286061:-1 gene:YPL141C transcript:YPL141C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FRK1 description:Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000006062]</Hit_def>
  <Hit_accession>YPL141C</Hit_accession>
  <Hit_len>865</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>1.58926e-12</Hsp_evalue>
      <Hsp_query-from>558</Hsp_query-from>
      <Hsp_query-to>1226</Hsp_query-to>
      <Hsp_hit-from>76</Hsp_hit-from>
      <Hsp_hit-to>301</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>112</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>241</Hsp_align-len>
      <Hsp_qseq>KVAVKKLYRPFQSRVFAK--RAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFM-GTDLSK-IMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARH---ADQEMTGYVVTRWYRAPEVILNWMHYTQTDMD----QLMLILKLTGTPPQYLVDRMDEN------VSCLLHFITRGPGTRHWLQFTFYG-AAAIDLLEKMLALDPEQR</Hsp_qseq>
      <Hsp_hseq>QVAIKLIKRDSISNDYRKEVKIYREINALKHLSHPNIVKLEEV------LQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVNEFCSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAG----YLPWDDDPNNPEGSDIGRLYNYINSTP-----LKFPDYILPIPRDLLRRMLVSDPKKR</Hsp_hseq>
      <Hsp_midline>+VA+K + R   S  + K  + YRE+  LKH+ H N++ L +V      L   +   +V+ +  G +  K I K  +  +     L  Q++ G+ YIHS G++HRDLK  NL ++++  L I DFG        ++ M     +  Y APE++++   Y     D     ++L   L G    YL    D N      +  L ++I   P     L+F  Y      DLL +ML  DP++R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>48</Hit_num>
  <Hit_id>YNL183C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:293137:295509:-1 gene:YNL183C transcript:YNL183C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:NPR1 description:Protein kinase; stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p; negatively regulates Ldb19p-mediated endocytosis through phosphorylation of Ldb19p, which prevents its association with the plasma membrane; Npr1p activity is negatively regulated via phosphorylation by the TOR complex; NPR1 has a paralog, PRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005127]</Hit_def>
  <Hit_accession>YNL183C</Hit_accession>
  <Hit_len>790</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>70.0922</Hsp_bit-score>
      <Hsp_score>170</Hsp_score>
      <Hsp_evalue>1.63422e-12</Hsp_evalue>
      <Hsp_query-from>564</Hsp_query-from>
      <Hsp_query-to>998</Hsp_query-to>
      <Hsp_hit-from>465</Hsp_hit-from>
      <Hsp_hit-to>613</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>49</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>155</Hsp_align-len>
      <Hsp_qseq>AVKKLYRPFQS---RVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLA-------RHADQEMTGYVVTRWYRAPEVIL</Hsp_qseq>
      <Hsp_hseq>AVKEFRTKFENESKRDYVKKITSEYCIGTTLNHPNIIETIEIVYENDRILQ------VMEYCEYDLFAIVMSNKMSYEEICCCFKQILTGVQYLHSIGLAHRDLKLDNCVINEKGIVKLIDFGAAVVFSYPFSKNLVEASGIVGSDPYLAPEVCI</Hsp_hseq>
      <Hsp_midline>AVK+    F++   R + K+   E  +   + H N+I  +++   ND + Q      VM +   DL  I+   K S +++     QIL G++Y+HS G+ HRDLK  N  +NE   +K++DFG A            E +G V +  Y APEV +</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>49</Hit_num>
  <Hit_id>YDL159W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:172481:174028:1 gene:YDL159W transcript:YDL159W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE7 description:Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318]</Hit_def>
  <Hit_accession>YDL159W</Hit_accession>
  <Hit_len>515</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>2.14924e-12</Hsp_evalue>
      <Hsp_query-from>489</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>193</Hsp_hit-from>
      <Hsp_hit-to>466</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>68</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>278</Hsp_align-len>
      <Hsp_qseq>QLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMK-HENVIGLVDVFTPNDTLDQFQDFYLVMPFMGT-DLSKIM-------KHGKQSDDK-------VQYLIYQILKGLKYIHSS-GIIHRDLKPGNLAVNEDCELKILDFGLARHADQEMTG-YVVTRWYRAPEVILNWMHYTQTDM--DQLMLILKLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>QLGKIGAGNSGTVVKALHVPDSKIVAKKTIPVEQNNSTIINQLVRELSIVKNVKPHENIITFYGAYY-NQHINN--EIIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKLINSIADTFVGTSTYMSPERIQGNVYSIKGDVWSLGLMIIELVTGEFPLGGHNDTPDGILDLLQRIVNEPSPR-LPKDRIYSKEMTDFVNRCCIKNERERSSIHELLHHDLI</Hsp_hseq>
      <Hsp_midline>QL  +G+G  GTV  ++ +     VA K +     +     +  REL ++K++K HEN+I     +  N  ++   +  ++M +     L KI+       + G  S  K       +  + Y +L GL +++    IIHRD+KP N+ +N   ++K+ DFG+++     +   +V T  Y +PE I   ++  + D+    LM+I  +TG  P    +   + +  LL  I   P  R   +   Y     D + +    +  +R +  E L H   </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>50</Hit_num>
  <Hit_id>YDL025C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:405344:407206:-1 gene:YDL025C transcript:YDL025C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RTK1 description:Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002183]</Hit_def>
  <Hit_accession>YDL025C</Hit_accession>
  <Hit_len>620</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.5514</Hsp_bit-score>
      <Hsp_score>166</Hsp_score>
      <Hsp_evalue>3.44735e-12</Hsp_evalue>
      <Hsp_query-from>501</Hsp_query-from>
      <Hsp_query-to>929</Hsp_query-to>
      <Hsp_hit-from>308</Hsp_hit-from>
      <Hsp_hit-to>452</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>47</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>152</Hsp_align-len>
      <Hsp_qseq>VGSGAYGTVCSSMDLVTGSKVAVKKLYRPF-------QSRV--FAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLA</Hsp_qseq>
      <Hsp_hseq>LGEGASGSV-SVVERTDGKLFACKMFRKPHLNNEGTNQSQLANYSKKVTTEFCIGSTLHHENIVETLDMLTEGDT------YLLVMEYAPYDFFNLVMSNLMTQDEVNCYFKQLCHGVNYLHSMGLAHRDLKLDNCVVTKDGILKLIDFGSA</Hsp_hseq>
      <Hsp_midline>+G GA G+V S ++   G   A K   +P        QS++  ++K+   E  +   + HEN++  +D+ T  DT      + LVM +   D   ++     + D+V     Q+  G+ Y+HS G+ HRDLK  N  V +D  LK++DFG A</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>51</Hit_num>
  <Hit_id>YDR490C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1431968:1434268:-1 gene:YDR490C transcript:YDR490C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH1 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]</Hit_def>
  <Hit_accession>YDR490C</Hit_accession>
  <Hit_len>766</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>68.9366</Hsp_bit-score>
      <Hsp_score>167</Hsp_score>
      <Hsp_evalue>3.45755e-12</Hsp_evalue>
      <Hsp_query-from>501</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>131</Hsp_hit-from>
      <Hsp_hit-to>391</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>74</Hsp_identity>
      <Hsp_positive>124</Hsp_positive>
      <Hsp_gaps>53</Hsp_gaps>
      <Hsp_align-len>284</Hsp_align-len>
      <Hsp_qseq>VGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQD---FYLVMPFM--GTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQEMTG----------------YVVTRWYRAPEVILNWMHYTQTDMD----QLMLILKLTGTPP-----QYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>LGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQ-KKVKYVTVEKLALQKLNGTKGIFKLFF------TFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLND--NYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLT---FQKVMKIQYAFTAG-----------FPQIVKDLVKKLLVRDPNDRLTIKQIKAHLFF</Hsp_hseq>
      <Hsp_midline>+G G+Y +V  +    +G K AVK L + +  R   K  Y  +  L   K     G+  +F        FQD    Y ++ +   G  L  I K+G  ++   +Y   QI+  +  +H+ GIIHRD+KP N+ ++++ ++K+ DFG A+   +E +                 +V T  Y +PE++ +  +YT +  D      +L   L G PP     +YL     + V  + +  T G           +     DL++K+L  DP  R T  +   H FF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>52</Hit_num>
  <Hit_id>YPL203W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:166256:167398:1 gene:YPL203W transcript:YPL203W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK2 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]</Hit_def>
  <Hit_accession>YPL203W</Hit_accession>
  <Hit_len>380</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>5.23481e-12</Hsp_evalue>
      <Hsp_query-from>498</Hsp_query-from>
      <Hsp_query-to>1265</Hsp_query-to>
      <Hsp_hit-from>75</Hsp_hit-from>
      <Hsp_hit-to>325</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>121</Hsp_positive>
      <Hsp_gaps>29</Hsp_gaps>
      <Hsp_align-len>268</Hsp_align-len>
      <Hsp_qseq>AVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYR---ELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFM-GTDLSKIMKHGKQSDDKV-QYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQEMTGYVVTRWYRAPEVILNWMHYTQTDMDQLMLIL--KLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQR-----PTASEALQHPFFS</Hsp_qseq>
      <Hsp_hseq>TLGTGSFGRVHLVRSVHNGRYYAIKVLKK--QQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTF------QDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPP---------YFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFS</Hsp_hseq>
      <Hsp_midline> +G+G++G V     +  G   A+K L +  Q  V  K+      E R+LK ++H  +I +   F         ++ ++VM ++ G +L  +++  ++  + V ++   +++  L+Y+H+  II+RDLKP N+ ++ +  +KI DFG A+           T  Y APEVI    +    D   L +++   L G  P Y    M      L   +   P         ++    +DLL K++  D  +R       + +   HP+FS</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>53</Hit_num>
  <Hit_id>YOL100W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:129237:132482:1 gene:YOL100W transcript:YOL100W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKH2 description:Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460]</Hit_def>
  <Hit_accession>YOL100W</Hit_accession>
  <Hit_len>1081</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>67.0106</Hsp_bit-score>
      <Hsp_score>162</Hsp_score>
      <Hsp_evalue>1.54618e-11</Hsp_evalue>
      <Hsp_query-from>501</Hsp_query-from>
      <Hsp_query-to>932</Hsp_query-to>
      <Hsp_hit-from>185</Hsp_hit-from>
      <Hsp_hit-to>326</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>12</Hsp_gaps>
      <Hsp_align-len>149</Hsp_align-len>
      <Hsp_qseq>VGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQD---FYLVMPFM--GTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLAR</Hsp_qseq>
      <Hsp_hseq>IGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQ-KKVKYVSIEKTALQKLNNSPSVVRLFS------TFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAK</Hsp_hseq>
      <Hsp_midline>+G GAY TV  +  + T  + A K L + +  R   K  Y  +      K  N   +V +F+       FQD    Y ++ +   G  LS + K+G   +   +Y   QI+  + Y+HS+GIIHRD+KP N+ ++ + ++K+ DFG A+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>54</Hit_num>
  <Hit_id>YOR233W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:775846:778248:1 gene:YOR233W transcript:YOR233W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN4 description:Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005759]</Hit_def>
  <Hit_accession>YOR233W</Hit_accession>
  <Hit_len>800</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>66.6254</Hsp_bit-score>
      <Hsp_score>161</Hsp_score>
      <Hsp_evalue>1.77294e-11</Hsp_evalue>
      <Hsp_query-from>501</Hsp_query-from>
      <Hsp_query-to>1226</Hsp_query-to>
      <Hsp_hit-from>52</Hsp_hit-from>
      <Hsp_hit-to>301</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>73</Hsp_identity>
      <Hsp_positive>121</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>262</Hsp_align-len>
      <Hsp_qseq>VGSGAYGTV------CSSMDLVTGSKVAVKKLYRPFQSRVFAK--RAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFM-GTDLSK-IMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARH--ADQE-MTGYVVTRWYRAPEVILNWMHYTQTDMD----QLMLILKLTGTPP--QYLVDRMDENVSCLLHFITRGPGTRHWLQFTFY-GAAAIDLLEKMLALDPEQR</Hsp_qseq>
      <Hsp_hseq>LGEGEFGKVKLGWTKASSSNEVP-KQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEV------LQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARLYKYITQTP-----LKFPEYITPIPRDLLRRILVPNPRRR</Hsp_hseq>
      <Hsp_midline>+G G +G V       SS + V   +VA+K + R    +   K  + YRE+  LKH+ H N+I L +V      L   +   +V+ F+ G +  K I +  +  +     L  Q++ G+ Y+H  G++HRDLK  NL +++   L I DFG       D E M     +  Y APE++++   Y     D     ++L   L G  P      +   ++++ L  +IT+ P     L+F  Y      DLL ++L  +P +R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>55</Hit_num>
  <Hit_id>YBR028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:294425:296002:-1 gene:YBR028C transcript:YBR028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK3 description:AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation [Source:SGD;Acc:S000000232]</Hit_def>
  <Hit_accession>YBR028C</Hit_accession>
  <Hit_len>525</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>2.1338e-11</Hsp_evalue>
      <Hsp_query-from>501</Hsp_query-from>
      <Hsp_query-to>1100</Hsp_query-to>
      <Hsp_hit-from>134</Hsp_hit-from>
      <Hsp_hit-to>377</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>60</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>56</Hsp_gaps>
      <Hsp_align-len>250</Hsp_align-len>
      <Hsp_qseq>VGSGAYGTVCSSMDLVTGSKVAVKKLYRP----FQSRVFAKR-----------------------AYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFM--GTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHA------DQE-------MTGYVVTRWYRAPEVILNWMHYTQTDMDQLMLIL--KLTGTPP------QYLVDRMDEN</Hsp_qseq>
      <Hsp_hseq>LGQGAYGKVLLVKDVNTSKLYAMKQLRKAEILISQTATDSKREDEDKNDGNNNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDNSKL------YLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQN</Hsp_hseq>
      <Hsp_midline>+G GAYG V    D+ T    A+K+L +      Q+   +KR                        + E  +L  ++H N++ L   F  N  L      YL++ ++  G     + +HG   +  V +   +I   L+++H+ G+++RDLKP N  +N+   L + DFGL++ +      D+E       +   + T  Y APE++L   +    D   L  +L   L G PP      + +++++ +N</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>56</Hit_num>
  <Hit_id>YHR102W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:316572:319814:1 gene:YHR102W transcript:YHR102W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIC1 description:Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]</Hit_def>
  <Hit_accession>YHR102W</Hit_accession>
  <Hit_len>1080</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>65.855</Hsp_bit-score>
      <Hsp_score>159</Hsp_score>
      <Hsp_evalue>3.37217e-11</Hsp_evalue>
      <Hsp_query-from>420</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>7</Hsp_hit-from>
      <Hsp_hit-to>276</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>132</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>292</Hsp_align-len>
      <Hsp_qseq>SSRKGFYRIEINKMVWEVPKRYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKH-ENVIGLVDVFTPNDTLDQFQDFYLVMPF-MGTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHAD------QEMTGYVVTRWYRAPEVILNWMHY-TQTDMDQLMLIL--KLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>NSKQGLAEGEM-----DVSSLFKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEV-EDVQREIQFLASLKQISNITRYYGSYLKDTSL------WIIMEHCAGGSLRSLLRPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTMAG---TPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYCDVEALR-----AMQLIIKSKPPR--LEDRSYSTSLKEFIALCLDEDPKERLSADDLLKSKFI</Hsp_hseq>
      <Hsp_midline>+S++G    E+     +V   + +   +G G +G V    ++ TG   A+K L     S    +   RE++ L  +K   N+      +  + +L      +++M    G  L  +++ GK  +  +  ++ ++L  LK IH   +IHRD+K  N+ +  +  +K+ DFG+A   +      Q M G   T ++ APEVI+  ++Y T+ D+  L +      TG PP   V+ +       +  I +    R  L+   Y  +  + +   L  DP++R +A + L+  F </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>57</Hit_num>
  <Hit_id>YCR008W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:128470:130281:1 gene:YCR008W transcript:YCR008W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAT4 description:Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]</Hit_def>
  <Hit_accession>YCR008W</Hit_accession>
  <Hit_len>603</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>6.07004e-11</Hsp_evalue>
      <Hsp_query-from>501</Hsp_query-from>
      <Hsp_query-to>989</Hsp_query-to>
      <Hsp_hit-from>322</Hsp_hit-from>
      <Hsp_hit-to>498</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>53</Hsp_identity>
      <Hsp_positive>88</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>182</Hsp_align-len>
      <Hsp_qseq>VGSGAYGTV--CSSMDLVTGSKVAVKKLY--RPFQSRV------FAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFM-GTDL-SKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFG------LARHADQEMTGYVV-TRWYRAPE</Hsp_qseq>
      <Hsp_hseq>LGKGAFGVVRICQKKNVSSQDGNKSEKLYAVKEFKRRTSESAEKYSKRLTSEFCISSSLHHTNIVTTLDLFQ-----DAKGEYCEVMEYCAGGDLFTLVVAAGKLEYMEADCFFKQLIRGVVYMHEMGVCHRDLKPENLLLTHDGVLKITDFGNSECFKMAWEKNIHLSGGVCGSSPYIAPE</Hsp_hseq>
      <Hsp_midline>+G GA+G V  C   ++ +      +KLY  + F+ R       ++KR   E  +   + H N++  +D+F      D   ++  VM +  G DL + ++  GK    +      Q+++G+ Y+H  G+ HRDLKP NL +  D  LKI DFG      +A   +  ++G V  +  Y APE</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>58</Hit_num>
  <Hit_id>YHR205W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:509363:511837:1 gene:YHR205W transcript:YHR205W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SCH9 description:AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]</Hit_def>
  <Hit_accession>YHR205W</Hit_accession>
  <Hit_len>824</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>7.32956e-11</Hsp_evalue>
      <Hsp_query-from>474</Hsp_query-from>
      <Hsp_query-to>1019</Hsp_query-to>
      <Hsp_hit-from>409</Hsp_hit-from>
      <Hsp_hit-to>591</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>33</Hsp_gaps>
      <Hsp_align-len>199</Hsp_align-len>
      <Hsp_qseq>PKRYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHEN-------------VIGLVDVF-TPNDTLDQFQDFYLVMPFM--GTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQEMTG-YVVTRWYRAPEVILNWMHYTQ</Hsp_qseq>
      <Hsp_hseq>PQDFEVLRLLGKGTFGQVY---------QVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTD-------LYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLLDETGYTK</Hsp_hseq>
      <Hsp_midline>P+ +  L  +G G +G V          +V  K   R +  +V +K+   +   + H   E              ++GL   F TP D        YLV  +M  G     + K G+ S+D+ ++ I +++  L+++H + I++RDLKP N+ ++ +  + + DFGL++   ++ T  +  T  Y APE++L+   YT+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>59</Hit_num>
  <Hit_id>YHR079C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:258244:261591:-1 gene:YHR079C transcript:YHR079C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IRE1 description:Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; role in homeostatic adaptation to ER stress; Kar2p binds inactive Ire1p and releases from it upon ER stress [Source:SGD;Acc:S000001121]</Hit_def>
  <Hit_accession>YHR079C</Hit_accession>
  <Hit_len>1115</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.6994</Hsp_bit-score>
      <Hsp_score>156</Hsp_score>
      <Hsp_evalue>8.08821e-11</Hsp_evalue>
      <Hsp_query-from>501</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>680</Hsp_hit-from>
      <Hsp_hit-to>980</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>78</Hsp_identity>
      <Hsp_positive>134</Hsp_positive>
      <Hsp_gaps>71</Hsp_gaps>
      <Hsp_align-len>313</Hsp_align-len>
      <Hsp_qseq>VGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMK-HENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQSDDKVQY--------LIYQILKGLKYIHSSGIIHRDLKPGNLAVN-------------EDCELKILDFGLARHADQEMTGYVV-------TRWYRAPEVI-----LNWMHYTQTDMDQLMLILKLTGTPP---QYLVDRMDE-NVSCLLHFI-TRGP---GTRHWLQFTFYG-----------------AAAIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>LGYGSSGTVVFQGSF-QGRPVAVKRMLIDF-----CDIALMEIKLLTESDDHPNVIR----YYCSETTDRF--LYIALELCNLNLQDLVESKNVSDENLKLQKEYNPISLLRQIASGVAHLHSLKIIHRDLKPQNILVSTSSRFTADQQTGAENLRILISDFGLCKKLDSGQSSFRTNLNNPSGTSGWRAPELLEESNNLQCQVETEHSSSRHTVVSSDSFYDPFTKRRLTRSIDIFSMGCVFYYILSKGKHPFGDKYSRESNIIRGIFSLDEMKCLHDRSLIAEATDLISQMIDHDPLKRPTAMKVLRHPLF</Hsp_hseq>
      <Hsp_midline>+G G+ GTV        G  VAVK++   F        A  E++LL     H NVI     +  ++T D+F   Y+ +     +L  +++    SD+ ++         L+ QI  G+ ++HS  IIHRDLKP N+ V+             E+  + I DFGL +  D   + +         T  +RAPE++     L     T+    +  ++   +   P   + L   +D  ++ C+ ++I ++G    G ++  +                      A A DL+ +M+  DP +RPTA + L+HP F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>60</Hit_num>
  <Hit_id>YKL126W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:205707:207749:1 gene:YKL126W transcript:YKL126W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YPK1 description:S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]</Hit_def>
  <Hit_accession>YKL126W</Hit_accession>
  <Hit_len>680</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>64.3142</Hsp_bit-score>
      <Hsp_score>155</Hsp_score>
      <Hsp_evalue>9.13444e-11</Hsp_evalue>
      <Hsp_query-from>492</Hsp_query-from>
      <Hsp_query-to>1265</Hsp_query-to>
      <Hsp_hit-from>350</Hsp_hit-from>
      <Hsp_hit-to>603</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>28</Hsp_gaps>
      <Hsp_align-len>270</Hsp_align-len>
      <Hsp_qseq>LFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPF-QSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFM--GTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLAR---HADQEMTGYVVTRWYRAPEVILNWMHYTQTDMDQLMLIL--KLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFT-FYGAAAIDLLEKMLALDPEQR---PTASEALQHPFFS</Hsp_qseq>
      <Hsp_hseq>LKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKL------YFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYY-----DEDVPKMYKKILQEP-----LVFPDGFDRDAKDLLIGLLSRDPTRRLGYNGADEIRNHPFFS</Hsp_hseq>
      <Hsp_midline>L  +G G++G V       T    A+K + + +  S+        E  +L  +    ++ L   F   + L      Y V+ F+  G     + K G+    + ++   ++L  L  +H   +++RDLKP N+ ++    + + DFGL +     D +   +  T  Y APE++L   +    D   L ++L   LTG PP Y     DE+V  +   I + P     L F   +   A DLL  +L+ DP +R     A E   HPFFS</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>61</Hit_num>
  <Hit_id>YKL166C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:134509:135705:-1 gene:YKL166C transcript:YKL166C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK3 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]</Hit_def>
  <Hit_accession>YKL166C</Hit_accession>
  <Hit_len>398</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>1.34217e-10</Hsp_evalue>
      <Hsp_query-from>492</Hsp_query-from>
      <Hsp_query-to>1265</Hsp_query-to>
      <Hsp_hit-from>91</Hsp_hit-from>
      <Hsp_hit-to>343</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>268</Hsp_align-len>
      <Hsp_qseq>LFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVF-AKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFM-GTDLSKIMKHGKQSDDKV-QYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQEMTGYVVTRWYRAPEVILNWMHYTQTDMDQLMLIL--KLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQR----PTASEALQ-HPFFS</Hsp_qseq>
      <Hsp_hseq>LRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDS------QQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPP---------FFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFN</Hsp_hseq>
      <Hsp_midline>L  +G+G++G V        G   A+K L +    ++   +    E R+L  + H  +I +   F  +      Q  ++VM ++ G +L  +++  ++  + V ++   ++   L+Y+HS  II+RDLKP N+ ++++  +KI DFG A++          T  Y APEV+    +    D     +++   L G  P Y  + M    + L   +   P         F+   A DLL+K++  D  +R       SE ++ HP+F+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>62</Hit_num>
  <Hit_id>YDR283C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:1025070:1030049:-1 gene:YDR283C transcript:YDR283C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:GCN2 description:Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]</Hit_def>
  <Hit_accession>YDR283C</Hit_accession>
  <Hit_len>1659</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.5438</Hsp_bit-score>
      <Hsp_score>153</Hsp_score>
      <Hsp_evalue>1.73626e-10</Hsp_evalue>
      <Hsp_query-from>774</Hsp_query-from>
      <Hsp_query-to>1049</Hsp_query-to>
      <Hsp_hit-from>806</Hsp_hit-from>
      <Hsp_hit-to>915</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>41</Hsp_identity>
      <Hsp_positive>55</Hsp_positive>
      <Hsp_gaps>18</Hsp_gaps>
      <Hsp_align-len>110</Hsp_align-len>
      <Hsp_qseq>KQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARH-----------------ADQEMTGYVVTRWYRAPEVILNWMHYTQT-DMDQLMLIL</Hsp_qseq>
      <Hsp_hseq>NQQRDEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNVKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVLDGTGHYNEKIDMYSLGIIF</Hsp_hseq>
      <Hsp_midline> Q  D+   L  QIL+ L YIHS GIIHRDLKP N+ ++E   +KI DFGLA++                 +   +T  + T  Y A EV+    HY +  DM  L +I </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>63</Hit_num>
  <Hit_id>YAL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:120225:124295:1 gene:YAL017W transcript:YAL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK1 description:PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015]</Hit_def>
  <Hit_accession>YAL017W</Hit_accession>
  <Hit_len>1356</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>63.1586</Hsp_bit-score>
      <Hsp_score>152</Hsp_score>
      <Hsp_evalue>2.29574e-10</Hsp_evalue>
      <Hsp_query-from>477</Hsp_query-from>
      <Hsp_query-to>995</Hsp_query-to>
      <Hsp_hit-from>1091</Hsp_hit-from>
      <Hsp_hit-to>1275</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>90</Hsp_positive>
      <Hsp_gaps>30</Hsp_gaps>
      <Hsp_align-len>194</Hsp_align-len>
      <Hsp_qseq>KRYSQLFAV---GSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRL------------LKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGT----DLSKIMKHGKQSDDKVQYLIY-QILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQ-EMTGYVVTRWYRAPEVI</Hsp_qseq>
      <Hsp_hseq>KKFSDFVSLQKMGEGAYGKVNLCIHKKNRYIVVIKMI---FKERILVDTWVRDRKLGTIPSEIQIMATLNKKPHENILRLLDFFEDDDY------YYIETPVHGETGCIDLFDLIEFKTNMTEFEAKLIFKQVVAGIKHLHDQGIVHRDIKDENVIVDSKGFVKIIDFGSAAYVKSGPFDVFVGTIDYAAPEVL</Hsp_hseq>
      <Hsp_midline>K++S   ++   G GAYG V   +       V +K +   F+ R+      R+ +L            L    HEN++ L+D F  +D       +Y+  P  G     DL  +++      +    LI+ Q++ G+K++H  GI+HRD+K  N+ V+    +KI+DFG A +        +V T  Y APEV+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>64</Hit_num>
  <Hit_id>YFL033C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VI:69115:74427:-1 gene:YFL033C transcript:YFL033C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:RIM15 description:Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase [Source:SGD;Acc:S000001861]</Hit_def>
  <Hit_accession>YFL033C</Hit_accession>
  <Hit_len>1770</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>62.7734</Hsp_bit-score>
      <Hsp_score>151</Hsp_score>
      <Hsp_evalue>3.22615e-10</Hsp_evalue>
      <Hsp_query-from>477</Hsp_query-from>
      <Hsp_query-to>932</Hsp_query-to>
      <Hsp_hit-from>792</Hsp_hit-from>
      <Hsp_hit-to>941</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>51</Hsp_identity>
      <Hsp_positive>81</Hsp_positive>
      <Hsp_gaps>16</Hsp_gaps>
      <Hsp_align-len>159</Hsp_align-len>
      <Hsp_qseq>KRYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTP--NDTLDQFQD---FYLVMPFM-GTDLSKIMKH-GKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLAR</Hsp_qseq>
      <Hsp_hseq>KDYDILKPISKGAYGSVYLARKKLTGDYFAIKVLRK---SDMIAKNQ------VTNVKSERAIMMVQSDKPYVARLFASFQNKDNLFLVMEYLPGGDLATLIKMMGYLPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLIDNAGHVKLTDFGLSR</Hsp_hseq>
      <Hsp_midline>K Y  L  +  GAYG+V  +   +TG   A+K L +   S + AK        + ++K E  I +V    P        FQ+    +LVM ++ G DL+ ++K  G   D   +  + +I+ G+  +H +GIIH DLKP NL ++    +K+ DFGL+R</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>65</Hit_num>
  <Hit_id>YJL164C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:109966:111159:-1 gene:YJL164C transcript:YJL164C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:TPK1 description:cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]</Hit_def>
  <Hit_accession>YJL164C</Hit_accession>
  <Hit_len>397</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>6.32618e-10</Hsp_evalue>
      <Hsp_query-from>492</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>90</Hsp_hit-from>
      <Hsp_hit-to>341</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>64</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>267</Hsp_align-len>
      <Hsp_qseq>LFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRL-LKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFM-GTDLSKIMKHGKQSDDKV-QYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQEMTGYVVTRWYRAPEVILNWMHYTQTDMDQLMLIL--KLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQR-----PTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>LRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTF------QDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTM-KTYEKILNAELRFP--------PFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWF</Hsp_hseq>
      <Hsp_midline>L  +G+G++G V        G   A+K L +    R+       + RL L  + H  +I +   F         Q  +++M ++ G +L  +++  ++  + V ++   ++   L+Y+HS  II+RDLKP N+ ++++  +KI DFG A++          T  Y APEV+    +    D     +++   L G  P Y  + M +    +L+   R P         F+     DLL +++  D  QR         +   HP+F</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>66</Hit_num>
  <Hit_id>YLR362W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XII:849866:852019:1 gene:YLR362W transcript:YLR362W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:STE11 description:Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]</Hit_def>
  <Hit_accession>YLR362W</Hit_accession>
  <Hit_len>717</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.8474</Hsp_bit-score>
      <Hsp_score>146</Hsp_score>
      <Hsp_evalue>1.10002e-09</Hsp_evalue>
      <Hsp_query-from>471</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>411</Hsp_hit-from>
      <Hsp_hit-to>712</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>121</Hsp_positive>
      <Hsp_gaps>68</Hsp_gaps>
      <Hsp_align-len>317</Hsp_align-len>
      <Hsp_qseq>VPKRYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQS------------------------------------------RVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLAR---------HADQEMTGYVVTRWYRAPEVILNWMHYTQTDM--DQLMLILKLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>TPKNWLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEY---VPG-GSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSV---FWMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQ---AIFKIGTNTTPEIPSWAT-----SEGKNFLRKAFELDYQYRPSALELLQHPWL</Hsp_hseq>
      <Hsp_midline> PK + +   +GSG++G+V   M+  TG  +AVK++     +                                          R        E+ LLK + HEN++           L+ F ++   +P  G+  S +  +G   +  +     QIL G+ Y+H   IIHRD+K  N+ ++    +KI DFG+++         +    + G V   ++ +PEV+       + D+     ++I   TG  P     +M    +         P    W       +   + L K   LD + RP+A E LQHP+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>67</Hit_num>
  <Hit_id>YGR052W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:593596:594705:1 gene:YGR052W transcript:YGR052W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FMP48 description:Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000003284]</Hit_def>
  <Hit_accession>YGR052W</Hit_accession>
  <Hit_len>369</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>1.34168e-09</Hsp_evalue>
      <Hsp_query-from>483</Hsp_query-from>
      <Hsp_query-to>992</Hsp_query-to>
      <Hsp_hit-from>2</Hsp_hit-from>
      <Hsp_hit-to>176</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>80</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>177</Hsp_align-len>
      <Hsp_qseq>YSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMK-HENVIGLVDVFTPND------TLDQFQDFYLVMPFMGTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQEMTGYVVTRWYRAPEV</Hsp_qseq>
      <Hsp_hseq>YTKLRSIQSGTFSTVYKAWSTTHNRYVALKITPKYKTSEANMKNEYDVMKILSSCNPHPNICSMLDFYTDDSYYIMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQID--MQKIIKQLCSAISFAHSLGIAHRDIKPENILLTINGDIKLADWGHAIQSPKSNDFQIGTDNYRAPET</Hsp_hseq>
      <Hsp_midline>Y++L ++ SG + TV  +        VA+K   +   S    K  Y  +++L     H N+  ++D +T +          +  D Y  +    +  S       Q D  +Q +I Q+   + + HS GI HRD+KP N+ +  + ++K+ D+G A  + +     + T  YRAPE </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>68</Hit_num>
  <Hit_id>YHR082C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:268459:271548:-1 gene:YHR082C transcript:YHR082C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KSP1 description:Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]</Hit_def>
  <Hit_accession>YHR082C</Hit_accession>
  <Hit_len>1029</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>60.4622</Hsp_bit-score>
      <Hsp_score>145</Hsp_score>
      <Hsp_evalue>1.5997e-09</Hsp_evalue>
      <Hsp_query-from>648</Hsp_query-from>
      <Hsp_query-to>995</Hsp_query-to>
      <Hsp_hit-from>143</Hsp_hit-from>
      <Hsp_hit-to>252</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>36</Hsp_identity>
      <Hsp_positive>64</Hsp_positive>
      <Hsp_gaps>14</Hsp_gaps>
      <Hsp_align-len>120</Hsp_align-len>
      <Hsp_qseq>KHENVIGLVDVFTPNDTLDQFQDFYLVMPFM-GTDLSKIMKHGK--QSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNE-DCELKILDFGLARHADQEMTGYVVTRWYRAPEVI</Hsp_qseq>
      <Hsp_hseq>RHQNIAALLDFF----------DSYIIMEYCSGGDLYEAIKADAVPKKTKSITHIITQIMDAIEYVHNKGIYHRDIKPENILISGIDWTIKLTDWGLATTDKTSMDRNVGSERYMSPELF</Hsp_hseq>
      <Hsp_midline>+H+N+  L+D F          D Y++M +  G DL + +K     +    + ++I QI+  ++Y+H+ GI HRD+KP N+ ++  D  +K+ D+GLA      M   V +  Y +PE+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>69</Hit_num>
  <Hit_id>YER129W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:V:417281:420709:1 gene:YER129W transcript:YER129W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAK1 description:Upstream serine/threonine kinase for the SNF1 complex; plays a role in pseudohyphal groth; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; SAK1 has a paralog, TOS3, that arose from the whole genome duplication [Source:SGD;Acc:S000000931]</Hit_def>
  <Hit_accession>YER129W</Hit_accession>
  <Hit_len>1142</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>2.74037e-09</Hsp_evalue>
      <Hsp_query-from>483</Hsp_query-from>
      <Hsp_query-to>929</Hsp_query-to>
      <Hsp_hit-from>133</Hsp_hit-from>
      <Hsp_hit-to>299</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>52</Hsp_identity>
      <Hsp_positive>87</Hsp_positive>
      <Hsp_gaps>26</Hsp_gaps>
      <Hsp_align-len>171</Hsp_align-len>
      <Hsp_qseq>YSQLFAVGSGAYGTVCSSMDLVTGSKVAVK------KLYRPF-----QSRVFAK-RAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSK-IMKHGKQSDDKVQYLIY-----QILKG----LKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLA</Hsp_qseq>
      <Hsp_hseq>YEIIKELGHGQHGKVKLARDILSKQLVAIKIVDRHEKKQRKFFTFIKSSKISENDKIKREIAIMKKCHHKHVVQLIEVL---DDL-KSRKIYLVLEYCSRGEVKWCPPDCMESDAKGPSLLSFQETREILRGVVLGLEYLHYQGIIHRDIKPANLLISGDGTVKISDFGVS</Hsp_hseq>
      <Hsp_midline>Y  +  +G G +G V  + D+++   VA+K      K  R F      S++    +  RE+ ++K   H++V+ L++V    D L + +  YLV+ +      K       +SD K   L+      +IL+G    L+Y+H  GIIHRD+KP NL ++ D  +KI DFG++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>70</Hit_num>
  <Hit_id>YOR351C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:995018:996511:-1 gene:YOR351C transcript:YOR351C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MEK1 description:Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]</Hit_def>
  <Hit_accession>YOR351C</Hit_accession>
  <Hit_len>497</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>58.9214</Hsp_bit-score>
      <Hsp_score>141</Hsp_score>
      <Hsp_evalue>2.81577e-09</Hsp_evalue>
      <Hsp_query-from>432</Hsp_query-from>
      <Hsp_query-to>992</Hsp_query-to>
      <Hsp_hit-from>153</Hsp_hit-from>
      <Hsp_hit-to>339</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>97</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>205</Hsp_align-len>
      <Hsp_qseq>GFYRIEINKMVWEVPKRYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKK--LYRPFQ-----SRVFAKRAYRELRLLKHMKHENVIGLVDVFTP-NDTLDQFQDFYLVMPFMGTDLSKIMKHG----KQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGN--LAVNEDCELKIL-DFGLARHAD---QEMTGYVVTRWYRAPEV</Hsp_qseq>
      <Hsp_hseq>GFLR-EVDQ--WEITNR-----IVGNGTFGHV-----LITHNSKERDEDVCYHPENYAVKIIKLKPNKFDKEARILLRLDHPNIIKVYHTFCDRNNHLYIFQD---LIP--GGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKERMHTVVGTPEYCAPEV</Hsp_hseq>
      <Hsp_midline>GF R E+++  WE+  R      VG+G +G V     L+T +     +   Y P        ++   +  +E R+L  + H N+I +   F   N+ L  FQD   ++P  G DL   +  G      S+ +   +++QIL+ L Y+H   I+HRDLK  N  L   E C   +L DFG+A+  +   + M   V T  Y APEV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>71</Hit_num>
  <Hit_id>YOL045W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XV:243497:246802:1 gene:YOL045W transcript:YOL045W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PSK2 description:PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]</Hit_def>
  <Hit_accession>YOL045W</Hit_accession>
  <Hit_len>1101</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>59.6918</Hsp_bit-score>
      <Hsp_score>143</Hsp_score>
      <Hsp_evalue>2.92832e-09</Hsp_evalue>
      <Hsp_query-from>483</Hsp_query-from>
      <Hsp_query-to>1241</Hsp_query-to>
      <Hsp_hit-from>841</Hsp_hit-from>
      <Hsp_hit-to>1092</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>66</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>275</Hsp_align-len>
      <Hsp_qseq>YSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRL------------LKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMG----TDLSKIMKHGKQSDDKVQYLIY-QILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQ-EMTGYVVTRWYRAPEVILNWMHYTQTDMD----QLMLILKLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASE</Hsp_qseq>
      <Hsp_hseq>FTILQVMGEGAYGKVNLCIHNREHYIVVIKMI---FKERILVDTWVRDRKLGTIPSEIQIMATLNKNSQENILKLLDFFEDDDY------YYIETPVHGETGSIDLFDVIEFKKDMVEHEAKLVFKQVVASIKHLHDQGIVHRDIKDENVIVDSHGFVKLIDFGSAAYIKSGPFDVFVGTMDYAAPEV-LGGSSYKGKPQDIWALGVLLYTIIYKENPYYNIDEILE-------------GELRFDKSEHVSEECISLIKRILTREVDKRPTIDE</Hsp_hseq>
      <Hsp_midline>++ L  +G GAYG V   +       V +K +   F+ R+      R+ +L            L     EN++ L+D F  +D       +Y+  P  G     DL  +++  K   +    L++ Q++  +K++H  GI+HRD+K  N+ V+    +K++DFG A +        +V T  Y APEV L    Y     D     ++L   +    P Y +D + E             G   + +        I L++++L  + ++RPT  E</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>72</Hit_num>
  <Hit_id>YBL105C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:II:14241:17696:-1 gene:YBL105C transcript:YBL105C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PKC1 description:Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201]</Hit_def>
  <Hit_accession>YBL105C</Hit_accession>
  <Hit_len>1151</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.7658</Hsp_bit-score>
      <Hsp_score>138</Hsp_score>
      <Hsp_evalue>1.07357e-08</Hsp_evalue>
      <Hsp_query-from>492</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>827</Hsp_hit-from>
      <Hsp_hit-to>1083</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>34</Hsp_gaps>
      <Hsp_align-len>274</Hsp_align-len>
      <Hsp_qseq>LFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPF---QSRVFAKRAYRELRLLK-HMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGT-DLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHA---DQEMTGYVVTRWYRAPEVILNWMHYTQT----DMDQLMLILKLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQR-----PTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>LKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRI------YFAMEFIGGGDLMWHVQNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPE-ILKEQEYTKAVDWWAFGVLLYQMLLCQSP--FSGDDEDEVFNAIL--------TDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFF</Hsp_hseq>
      <Hsp_midline>L  +G G +G V  S    T    A+K L +        + + RA +++ LL    KH  +  L   F   + +      Y  M F+G  DL   +++ + S  + ++   ++L  LKY H +G+I+RDLK  N+ +  +  +KI D+GL +         + +  T  + APE IL    YT+         L+  + L  +P  +  D  DE  + +L        T   L         + + + +L  DPE+R       A E ++ PFF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>73</Hit_num>
  <Hit_id>YDL028C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:400997:403291:-1 gene:YDL028C transcript:YDL028C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:MPS1 description:Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]</Hit_def>
  <Hit_accession>YDL028C</Hit_accession>
  <Hit_len>764</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>1.07463e-08</Hsp_evalue>
      <Hsp_query-from>624</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>486</Hsp_hit-from>
      <Hsp_hit-to>716</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>63</Hsp_identity>
      <Hsp_positive>109</Hsp_positive>
      <Hsp_gaps>36</Hsp_gaps>
      <Hsp_align-len>240</Hsp_align-len>
      <Hsp_qseq>ELRLLKHMK-HENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIM--KHGKQSD-DKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQEMTGY-----VVTRWYRAPEVILNWMHYTQTDMDQ------------------LMLILKLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>EIELLEKLKDQKRVIQLLD-YEMGDGL-----LYLIMECGDHDLSQILNQRSGMPLDFNFVRFYTKEMLLCIKVVHDAGIVHSDLKPANFVLVKGI-LKIIDFGIANAVPEHTVNIYRETQIGTPNYMAPEALV-AMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYGKPP-YGSFQGQNRLLAIMNPDVKIPFPEHTSNNEKIPKSAIELMKACLYRNPDKRWTVDKVLSSTFL</Hsp_hseq>
      <Hsp_midline>E+ LL+ +K  + VI L+D +   D L      YL+M     DLS+I+  + G   D + V++   ++L  +K +H +GI+H DLKP N  + +   LKI+DFG+A    +          + T  Y APE ++  M+YTQ   +Q                   ++   + G PP Y   +    +  +++   + P   H         +AI+L++  L  +P++R T  + L   F </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>74</Hit_num>
  <Hit_id>YGL180W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:160065:162758:1 gene:YGL180W transcript:YGL180W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ATG1 description:Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation [Source:SGD;Acc:S000003148]</Hit_def>
  <Hit_accession>YGL180W</Hit_accession>
  <Hit_len>897</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>57.3806</Hsp_bit-score>
      <Hsp_score>137</Hsp_score>
      <Hsp_evalue>1.18234e-08</Hsp_evalue>
      <Hsp_query-from>450</Hsp_query-from>
      <Hsp_query-to>1226</Hsp_query-to>
      <Hsp_hit-from>13</Hsp_hit-from>
      <Hsp_hit-to>313</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>72</Hsp_identity>
      <Hsp_positive>128</Hsp_positive>
      <Hsp_gaps>66</Hsp_gaps>
      <Hsp_align-len>313</Hsp_align-len>
      <Hsp_qseq>INKMVWEVPKRYSQLFAVGSGAYGTVCSSMDLVTGSK-VAVKKLYRP-FQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGT-DLSKIMKHGKQ------------------SDDK-------VQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVN------EDCE---------------LKILDFGLARHADQEMTGYVV--TRWYRAPEVILNWMHYT-QTDMDQLMLIL--KLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQR</Hsp_qseq>
      <Hsp_hseq>VNHNLMASAGNYTAEKEIGKGSFATVYRGHLTSDKSQHVAIKEVSRAKLKNKKLLENLEIEIAILKKIKHPHIVGLIDCERTS------TDFYLIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPE-ILNYQKYNAKADLWSVGTVVFEMCCGTPPFRASNHLE-----LFKKIKRANDVITFPSYCNIEPELKELICSLLTFDPAQR</Hsp_hseq>
      <Hsp_midline>+N  +      Y+    +G G++ TV         S+ VA+K++ R   +++   +    E+ +LK +KH +++GL+D    +       DFYL+M +    DL+ ++K  K+                  S++        V   + Q+   LK++ S  ++HRD+KP NL ++       D +               LKI DFG AR          +  +  Y APE ILN+  Y  + D+  +  ++     GTPP    + ++     L   I R      +  +        +L+  +L  DP QR</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>75</Hit_num>
  <Hit_id>YDL017W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:424209:425732:1 gene:YDL017W transcript:YDL017W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CDC7 description:DDK (Dbf4-dependent kinase) catalytic subunit; required for origin firing and replication fork progression in mitotic S phase through phosphorylation of Mcm2-7p complexes and Cdc45p; kinase activity correlates with cyclical DBF4 expression; required for pre-meiotic DNA replication, meiotic DSB formation, recruitment of monopolin complex to kinetochores during meiosis I, regulation of meiosis-specific Ndt80p; mutation complemented by human CDC7 and DBF4 co-expression [Source:SGD;Acc:S000002175]</Hit_def>
  <Hit_accession>YDL017W</Hit_accession>
  <Hit_len>507</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>2.30401e-08</Hsp_evalue>
      <Hsp_query-from>471</Hsp_query-from>
      <Hsp_query-to>929</Hsp_query-to>
      <Hsp_hit-from>29</Hsp_hit-from>
      <Hsp_hit-to>186</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>77</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>178</Hsp_align-len>
      <Hsp_qseq>VPKRYSQLFAVGSGAYGTVCSSMDLVT-------------GSK-VAVKKLYRPFQSRVFAKRAYRELRLLKHMKHEN-VIGLVDVFTPNDTL---------DQFQDFYLVMPFMGTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKIL-DFGLA</Hsp_qseq>
      <Hsp_hseq>IENEYKLIDKIGEGTFSSVYKAKDITGKITKKFASHFWNYGSNYVALKKIYVTSS----PQRIYNELNLLYIMTGSSRVAPLCDAKRVRDQVIAVLPYYPHEEFRTFYRDLPIKG----------------IKKYIWELLRALKFVHSKGIIHRDIKPTNFLFNLELGRGVLVDFGLA</Hsp_hseq>
      <Hsp_midline>+   Y  +  +G G + +V  + D+               GS  VA+KK+Y         +R Y EL LL  M   + V  L D     D +         ++F+ FY  +P  G                ++  I+++L+ LK++HS GIIHRD+KP N   N +    +L DFGLA</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>76</Hit_num>
  <Hit_id>YPL150W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:268188:270893:1 gene:YPL150W transcript:YPL150W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding description:Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]</Hit_def>
  <Hit_accession>YPL150W</Hit_accession>
  <Hit_len>901</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>56.225</Hsp_bit-score>
      <Hsp_score>134</Hsp_score>
      <Hsp_evalue>2.7444e-08</Hsp_evalue>
      <Hsp_query-from>801</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>137</Hsp_hit-from>
      <Hsp_hit-to>287</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>50</Hsp_identity>
      <Hsp_positive>75</Hsp_positive>
      <Hsp_gaps>23</Hsp_gaps>
      <Hsp_align-len>164</Hsp_align-len>
      <Hsp_qseq>LIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQEMTGYVV--TRWYRAPEVILNWMHYT-QTDMDQLMLILK--LTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAI-----DLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>LFAQISGAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTRECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITG----YLPFDDDDEAKTKWKIVNEEPK---------YDAKVIPDDARDLISRLLAKNPGERPSLSQVLRHPFL</Hsp_hseq>
      <Hsp_midline>L  QI   + Y HS   +HRDLK  N+ ++++   K+ DFG  R    + T   V  T  Y APE+I    +   + D+  L +IL   +TG    YL    D+        +   P          Y A  I     DL+ ++LA +P +RP+ S+ L+HPF </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>77</Hit_num>
  <Hit_id>YDL214C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:74446:76545:-1 gene:YDL214C transcript:YDL214C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PRR2 description:Serine/threonine protein kinase; inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance; PRR2 has a paralog, NPR1, that arose from the whole genome duplication [Source:SGD;Acc:S000002373]</Hit_def>
  <Hit_accession>YDL214C</Hit_accession>
  <Hit_len>699</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>55.4546</Hsp_bit-score>
      <Hsp_score>132</Hsp_score>
      <Hsp_evalue>4.17729e-08</Hsp_evalue>
      <Hsp_query-from>516</Hsp_query-from>
      <Hsp_query-to>992</Hsp_query-to>
      <Hsp_hit-from>346</Hsp_hit-from>
      <Hsp_hit-to>534</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>89</Hsp_positive>
      <Hsp_gaps>32</Hsp_gaps>
      <Hsp_align-len>190</Hsp_align-len>
      <Hsp_qseq>YGTVCSSMDLVT------------GSKVAVKKLYRPFQSRVFAKRAYR-------ELRLLKHMKHENVIGLVDVFTPN--DTLDQFQD---FYLVMPFMGTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLAR--H---ADQ--EMTGYVVTRWYRAPEV</Hsp_qseq>
      <Hsp_hseq>YSNIEASTDLVSRKYRDLDVVLGEGSGGKVKLVQRVLDNKVFALKEYRSKKKRESERKYIKNIISEYCIAST-LKNPNICETLEILYEKGKIFQILEYCEYDLFSLVMSEKMHYEEICCLFKQLINGVKYLHDIGLSHRDLKLDNCVVTRRGILKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEV</Hsp_hseq>
      <Hsp_midline>Y  + +S DLV+            GS   VK + R   ++VFA + YR       E + +K++  E  I    +  PN  +TL+   +    + ++ +   DL  ++   K   +++  L  Q++ G+KY+H  G+ HRDLK  N  V     LK++DFG +   H   + Q  E  G V +  Y +PEV</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>78</Hit_num>
  <Hit_id>YPL209C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XVI:156490:157593:-1 gene:YPL209C transcript:YPL209C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:IPL1 description:Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]</Hit_def>
  <Hit_accession>YPL209C</Hit_accession>
  <Hit_len>367</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.299</Hsp_bit-score>
      <Hsp_score>129</Hsp_score>
      <Hsp_evalue>6.73139e-08</Hsp_evalue>
      <Hsp_query-from>603</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>145</Hsp_hit-from>
      <Hsp_hit-to>355</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>95</Hsp_positive>
      <Hsp_gaps>19</Hsp_gaps>
      <Hsp_align-len>225</Hsp_align-len>
      <Hsp_qseq>FAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMK-HGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFG--LARHADQEMTGYVVTRWYRAPEVILNWMHYTQTDMDQLMLIL--KLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>LQKQFRREVEIQTSLNHPNLTKSYGYFH-----DEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPP-FEEEMKDTTYKRIAALDIKMPSN--------ISQDAQDLILKLLKYDPKDRMRLGDVKMHPWI</Hsp_hseq>
      <Hsp_midline>  K+  RE+ +   + H N+      F      D+ + + L+   +  ++ K+++ HG  +D      IYQI   L Y+H   IIHRD+KP N+ +  +  +K+ DFG  +    +        T  Y +PE++ +  +    D   L ++    LTG PP +  +  D     +     + P              A DL+ K+L  DP+ R    +   HP+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>79</Hit_num>
  <Hit_id>YJL187C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:76803:79262:-1 gene:YJL187C transcript:YJL187C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SWE1 description:Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]</Hit_def>
  <Hit_accession>YJL187C</Hit_accession>
  <Hit_len>819</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>54.6842</Hsp_bit-score>
      <Hsp_score>130</Hsp_score>
      <Hsp_evalue>7.23657e-08</Hsp_evalue>
      <Hsp_query-from>477</Hsp_query-from>
      <Hsp_query-to>1049</Hsp_query-to>
      <Hsp_hit-from>442</Hsp_hit-from>
      <Hsp_hit-to>643</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>54</Hsp_identity>
      <Hsp_positive>99</Hsp_positive>
      <Hsp_gaps>31</Hsp_gaps>
      <Hsp_align-len>212</Hsp_align-len>
      <Hsp_qseq>KRYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKH------MKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSK------------IMKHGKQSDDKVQYLIYQILKGLKYIHSSG-IIHRDLKPGNLAVNEDCELKILDFGLARHADQEMTGYVVT--RWYRAPEVILNWMHYTQTDMDQLMLIL</Hsp_qseq>
      <Hsp_hseq>EKFTNVHSIGKGQFSTVYQVTFAQTNKKYAIKAI-KPNKYNSL-KRILLEIKILNEVTNQITMDQEGKEYIIDYISSW----KFQNSYYIM----TELCENGNLDGFLQEQVIAKKKRLEDWRIWKIIVELSLALRFIHDSCHIVHLDLKPANVMITFEGNLKLGDFGMATHLPLEDKSFENEGDREYIAPEIISDCTYDYKADIFSLGLMI</Hsp_hseq>
      <Hsp_midline>++++ + ++G G + TV       T  K A+K + +P +     KR   E+++L        M  E    ++D  +      +FQ+ Y +M    T+L +            I K  +  D ++  +I ++   L++IH S  I+H DLKP N+ +  +  LK+ DFG+A H   E   +     R Y APE+I +  +  + D+  L L++</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>80</Hit_num>
  <Hit_id>YCR091W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:III:274404:276566:1 gene:YCR091W transcript:YCR091W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN82 description:Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]</Hit_def>
  <Hit_accession>YCR091W</Hit_accession>
  <Hit_len>720</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>53.9138</Hsp_bit-score>
      <Hsp_score>128</Hsp_score>
      <Hsp_evalue>1.3951e-07</Hsp_evalue>
      <Hsp_query-from>474</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>321</Hsp_hit-from>
      <Hsp_hit-to>602</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>70</Hsp_identity>
      <Hsp_positive>123</Hsp_positive>
      <Hsp_gaps>45</Hsp_gaps>
      <Hsp_align-len>295</Hsp_align-len>
      <Hsp_qseq>PKRYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYR-PFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPF-MGTDLSKIMKHGKQ---SDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHA--------------DQEM-------TGYVVTRWYRAPEVILNWMHYTQTDMDQLMLIL--KLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQR----PTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>PQSFEKIRLLGQGDVGKVYLVRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPFIVTLYHSFQTKDYL------YLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTP-FKGDNSNETFSNILTKDVKFPHDKE------VSKNCKDLIKKLLNKNEAKRLGSKSGAADIKRHPFF</Hsp_hseq>
      <Hsp_midline>P+ + ++  +G G  G V    +  T    A+K L +     R   KR   E  +L    H  ++ L   F   D L      YL M + MG +  + ++  K    +++  ++   +++  L+Y+H  G I+RDLKP N+ +++   + + DF L+  A              D ++         +V T  Y APEVI    H    D   L +++   L G  P +  D  +E  S +L    + P  +             DL++K+L  +  +R      A++  +HPFF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>81</Hit_num>
  <Hit_id>YNR047W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:708523:711204:1 gene:YNR047W transcript:YNR047W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FPK1 description:Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]</Hit_def>
  <Hit_accession>YNR047W</Hit_accession>
  <Hit_len>893</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.6026</Hsp_bit-score>
      <Hsp_score>122</Hsp_score>
      <Hsp_evalue>7.43476e-07</Hsp_evalue>
      <Hsp_query-from>474</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>493</Hsp_hit-from>
      <Hsp_hit-to>777</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>117</Hsp_positive>
      <Hsp_gaps>48</Hsp_gaps>
      <Hsp_align-len>298</Hsp_align-len>
      <Hsp_qseq>PKRYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYR-PFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPF-MGTDLSKIMKHGKQS---DDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQE------------------------MTGYVVTRWYRAPEVILNWMHYTQTDMDQLMLIL--KLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQR----PTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>PQSFEKIRLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQEILATSNHPFIVTLYHSFQSEDYL------YLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTP-FKGDNTNETFTNILKNEVSFPNNNEISR------TCKDLIKKLLTKNESKRLGCKMGAADVKKHPFF</Hsp_hseq>
      <Hsp_midline>P+ + ++  +G G  G V    +  T    A+K L +     R   KR   E  +L    H  ++ L   F   D L      YL M + MG +  + ++  K     +D  ++   ++   L+Y+H  G I+RDLKP N+ +++   + + DF L+  A                              +V T  Y APEVI    H    D   L +++   L G  P +  D  +E  + +L      P      +         DL++K+L  +  +R      A++  +HPFF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>82</Hit_num>
  <Hit_id>YKL198C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:68232:70220:-1 gene:YKL198C transcript:YKL198C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK1 description:Putative serine/threonine protein kinase; regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein; PTK1 has a paralog, PTK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001681]</Hit_def>
  <Hit_accession>YKL198C</Hit_accession>
  <Hit_len>662</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>8.062e-07</Hsp_evalue>
      <Hsp_query-from>603</Hsp_query-from>
      <Hsp_query-to>998</Hsp_query-to>
      <Hsp_hit-from>239</Hsp_hit-from>
      <Hsp_hit-to>384</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>46</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>20</Hsp_gaps>
      <Hsp_align-len>149</Hsp_align-len>
      <Hsp_qseq>FAKRAYRELRLLKHMKHE----NVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDL-SKIMKHGKQSDDKVQ-YLIY-QILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLAR--HAD--------QEMTGYVVTRWYRAPEVIL</Hsp_qseq>
      <Hsp_hseq>FYKRCSKEFIIAKQLSHHVHITNTFLLVKVPT---TVYTTRGWGFVMELGLRDLFAMIQKSGWRSVALAEKFCIFKQVACGVKFCHDQGIAHRDLKPENVLLSPDGVCKLTDFGISDWYHTDPHDLSSPVKKCAGMIGSPPYAPPEVMF</Hsp_hseq>
      <Hsp_midline>F KR  +E  + K + H     N   LV V T   T+   + +  VM     DL + I K G +S    + + I+ Q+  G+K+ H  GI HRDLKP N+ ++ D   K+ DFG++   H D        ++  G + +  Y  PEV+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>83</Hit_num>
  <Hit_id>YJR059W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:545787:548243:1 gene:YJR059W transcript:YJR059W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PTK2 description:Serine/threonine protein kinase; involved in regulation of ion transport across plasma membrane; carboxyl terminus is essential for glucose-dependent Pma1p activation via phosphorylation of Pma1p-Ser899; enhances spermine uptake; PTK2 has a paralog, PTK1, that arose from the whole genome duplication [Source:SGD;Acc:S000003820]</Hit_def>
  <Hit_accession>YJR059W</Hit_accession>
  <Hit_len>818</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>51.2174</Hsp_bit-score>
      <Hsp_score>121</Hsp_score>
      <Hsp_evalue>1.03407e-06</Hsp_evalue>
      <Hsp_query-from>603</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>298</Hsp_hit-from>
      <Hsp_hit-to>562</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>65</Hsp_identity>
      <Hsp_positive>107</Hsp_positive>
      <Hsp_gaps>55</Hsp_gaps>
      <Hsp_align-len>270</Hsp_align-len>
      <Hsp_qseq>FAKRAYRELRLLKHMKHE----NVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHG--KQSDDKVQYLIY-QILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLA----------RHADQEMTGYVVTRWYRAPEVIL--NWMHYTQT--------DMDQ----LMLILKLTGTPPQYLVD------RMDENVSCLLHFITR-------------GPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>FYKRCSKEFIIAKHLSHNVHITNTFYLLKVPT---TTYTTRGWGFIMELGVKDLFQLMERTGWKNVPFNEKYCLFKQVAQGIKFCHDNGIAHRDLKPENVLISKEGICKLTDFGISDWYHVIPHDYTSPVKTCQGMIGSPPYTPPEVMYFDAKKHYPEKFQKPYNPLAMDSYALGIMLITMINNIIP--FIDSCNTDARFREFEVSYDNFINHQNPHFRDKGCHKPGPGSEYSLARNFKNTDATRIAWRLADPNPATRYTMDDLFNDPFF</Hsp_hseq>
      <Hsp_midline>F KR  +E  + KH+ H     N   L+ V T   T    + +  +M     DL ++M+    K      +Y ++ Q+ +G+K+ H +GI HRDLKP N+ ++++   K+ DFG++              +   G + +  Y  PEV+      HY +          MD     +MLI  +    P   +D      R  E      +FI               GPG+ + L   F    A  +  ++   +P  R T  +    PFF</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>84</Hit_num>
  <Hit_id>YNL161W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XIV:332597:334867:1 gene:YNL161W transcript:YNL161W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CBK1 description:Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]</Hit_def>
  <Hit_accession>YNL161W</Hit_accession>
  <Hit_len>756</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.8322</Hsp_bit-score>
      <Hsp_score>120</Hsp_score>
      <Hsp_evalue>1.14399e-06</Hsp_evalue>
      <Hsp_query-from>501</Hsp_query-from>
      <Hsp_query-to>929</Hsp_query-to>
      <Hsp_hit-from>358</Hsp_hit-from>
      <Hsp_hit-to>497</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>45</Hsp_identity>
      <Hsp_positive>76</Hsp_positive>
      <Hsp_gaps>25</Hsp_gaps>
      <Hsp_align-len>154</Hsp_align-len>
      <Hsp_qseq>VGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDT------LDQFQD---FYLVMPFM-GTDL-SKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLA</Hsp_qseq>
      <Hsp_hseq>IGKGAFGEVRLVQKKDTGKIYAMKTL---LKSEMYKKDQ------LAHVKAER-----DVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLS</Hsp_hseq>
      <Hsp_midline>+G GA+G V       TG   A+K L    +S ++ K        L H+K E      DV   +D+         FQD    YL+M F+ G DL + +++    ++D  ++ + + +  ++ IH  G IHRD+KP N+ ++    +K+ DFGL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>85</Hit_num>
  <Hit_id>YAR018C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:I:170396:171703:-1 gene:YAR018C transcript:YAR018C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:KIN3 description:Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol [Source:SGD;Acc:S000000071]</Hit_def>
  <Hit_accession>YAR018C</Hit_accession>
  <Hit_len>435</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>50.0618</Hsp_bit-score>
      <Hsp_score>118</Hsp_score>
      <Hsp_evalue>1.73301e-06</Hsp_evalue>
      <Hsp_query-from>483</Hsp_query-from>
      <Hsp_query-to>1250</Hsp_query-to>
      <Hsp_hit-from>25</Hsp_hit-from>
      <Hsp_hit-to>339</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>71</Hsp_identity>
      <Hsp_positive>126</Hsp_positive>
      <Hsp_gaps>81</Hsp_gaps>
      <Hsp_align-len>326</Hsp_align-len>
      <Hsp_qseq>YSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGT-DLSKIMKHGKQS-----DDKVQYLIYQILKGLKYIH---------------------SSGIIHRDLKPGNL---------AVNEDCE------------------------------LKILDFGLARHAD---QEMTGYVVTRWYRAPEVILNWMHYTQTDMDQL-MLILKLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQ</Hsp_qseq>
      <Hsp_hseq>YQVLEEIGRGSFGSVRKVIHIPTKKLLVRKDIKYGHMNSKERQQLIAECSILSQLKHENIVE----FYNWDFDEQKEVLYLYMEYCSRGDLSQMIKHYKQEHKYIPEKIVWGILAQLLTALYKCHYGVELPTLTTIYDRMKPPVKGKNIVIHRDLKPGNIFLSYDDSDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLAKSLETSIQFATTYVGTPYYMSPEVLMDQPYSPLSDIWSLGCVIFEMCSLHPPF-------QAKNYLELQTKIKNGKCDTVPEYYSRGLNAIIHSMIDVNLRTRPSTFELLQ</Hsp_hseq>
      <Hsp_midline>Y  L  +G G++G+V   + + T   +  K +     +    ++   E  +L  +KHEN++     F   D  +Q +  YL M +    DLS+++KH KQ      +  V  ++ Q+L  L   H                      + +IHRDLKPGN+          +NE  +                              +K+ DFGLA+  +   Q  T YV T +Y +PEV+++  +   +D+  L  +I ++    P +            L   T+    +      +Y      ++  M+ ++   RP+  E LQ</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>86</Hit_num>
  <Hit_id>YJL128C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:X:178097:180103:-1 gene:YJL128C transcript:YJL128C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:PBS2 description:MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000003664]</Hit_def>
  <Hit_accession>YJL128C</Hit_accession>
  <Hit_len>668</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>7.29862e-06</Hsp_evalue>
      <Hsp_query-from>492</Hsp_query-from>
      <Hsp_query-to>1262</Hsp_query-to>
      <Hsp_hit-from>363</Hsp_hit-from>
      <Hsp_hit-to>623</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>69</Hsp_identity>
      <Hsp_positive>116</Hsp_positive>
      <Hsp_gaps>24</Hsp_gaps>
      <Hsp_align-len>271</Hsp_align-len>
      <Hsp_qseq>LFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFM-GTDLSKIMKHGKQ----SDDKVQYLIYQILKGLKYIHSS-GIIHRDLKPGNLAVNED-CELKILDFGLARHADQEMTGYVV-TRWYRAPEVI--LNWMHYT---QTDMDQLML-ILKLTGTPPQYLVDRMDENVSCLLHFITRGPGTRHWLQFTFYGAAAIDLLEKMLALDPEQRPTASEALQHPFF</Hsp_qseq>
      <Hsp_hseq>LDELGHGNYGNVSKVLHKPTNVIMATKEVRLELDEAKF-RQILMELEVLHKCNSPYIVDFYGAFFIEGAV------YMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSANQGTVKLCDFGVSGNLVASLAKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYPPETYD-NIFSQLSAIVDGPPPR--LPSDKFSSDAQDFVSLCLQKIPERRPTYAALTEHPWL</Hsp_hseq>
      <Hsp_midline>L  +G G YG V   +   T   +A K++        F ++   EL +L       ++     F     +      Y+ M +M G  L KI     +     + ++ ++   ++ GLK +     IIHRD+KP N+  + +   +K+ DFG++ +    +    +  + Y APE I  LN    T   Q+D+  L L IL++      Y  +  D N+   L  I  GP  R  L    + + A D +   L   PE+RPT +   +HP+ </Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
<Hit>
  <Hit_num>87</Hit_num>
  <Hit_id>YGR092W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VII:668189:669907:1 gene:YGR092W transcript:YGR092W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DBF2 description:Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]</Hit_def>
  <Hit_accession>YGR092W</Hit_accession>
  <Hit_len>572</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>48.1358</Hsp_bit-score>
      <Hsp_score>113</Hsp_score>
      <Hsp_evalue>7.90009e-06</Hsp_evalue>
      <Hsp_query-from>483</Hsp_query-from>
      <Hsp_query-to>929</Hsp_query-to>
      <Hsp_hit-from>177</Hsp_hit-from>
      <Hsp_hit-to>322</Hsp_hit-to>
      <Hsp_query-frame>3</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>66</Hsp_positive>
      <Hsp_gaps>9</Hsp_gaps>
      <Hsp_align-len>152</Hsp_align-len>
      <Hsp_qseq>YSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVF-AKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFM-GTDLSKIMKHGKQ-SDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLA</Hsp_qseq>
      <Hsp_hseq>FEMITQVGQGGYGQVYLARKKDTKEVCALKILNKKLLFKLNETKHVLTERDILTTTRSEWLVKLLYAF------QDLQSLYLAMEFVPGGDFRTLLINTRCLKSGHARFYISEMFCAVNALHDLGYTHRDLKPENFLIDAKGHIKLTDFGLA</Hsp_hseq>
      <Hsp_midline>+  +  VG G YG V  +    T    A+K L +    ++   K    E  +L   + E ++ L+  F         Q  YL M F+ G D   ++ + +       ++ I ++   +  +H  G  HRDLKP N  ++    +K+ DFGLA</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2474461167</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>7</Iteration_iter-num>
  <Iteration_query-ID>Query_7</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054759-RA transcript Note:&quot;Similar to Flnc Filamin-C (Mus musculus)&quot; offset:0 AED:0.19 eAED:0.21 QI:0|0.05|0.13|0.86|1|1|37|616|1891</Iteration_query-def>
  <Iteration_query-len>6292</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YDR129C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:IV:713340:715379:-1 gene:YDR129C transcript:YDR129C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:SAC6 description:Fimbrin, actin-bundling protein; cooperates with Scp1p in organization and maintenance of the actin cytoskeleton; phosphorylated by Cdc28p/Clb2p in metaphase on T103, to regulate conformation, and modulate actin filament binding affinity and actin cable dynamics; relocalizes from the plasma membrane to the cytoplasm upon DNA replication stress; human homologs PLS3 and LCP1 implicated in spinocerebellar ataxia type 2 (SCA2) can each complement yeast null mutant [Source:SGD;Acc:S000002536]</Hit_def>
  <Hit_accession>YDR129C</Hit_accession>
  <Hit_len>642</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>52.373</Hsp_bit-score>
      <Hsp_score>124</Hsp_score>
      <Hsp_evalue>7.29186e-07</Hsp_evalue>
      <Hsp_query-from>337</Hsp_query-from>
      <Hsp_query-to>741</Hsp_query-to>
      <Hsp_hit-from>215</Hsp_hit-from>
      <Hsp_hit-to>366</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>39</Hsp_identity>
      <Hsp_positive>71</Hsp_positive>
      <Hsp_gaps>17</Hsp_gaps>
      <Hsp_align-len>152</Hsp_align-len>
      <Hsp_qseq>ENVSVALEFLERENIKLVSIDSKAIVDGNLKLILGLVWTLI-----------LHYSISMPVWEDEEDDEAKKQTPKQRLLGWIQHKLP----DLPISNFSQDWKDGRALGALVDSCAPGLCPD--WEIWDVIAPEEIVDPNVDEHSVMTYLS</Hsp_qseq>
      <Hsp_hseq>ENANIVINSAKAIGCVVVNVHSEDIIEGREHLILGLIWQIIRRGLLSKIDIKLHPELYRLLEDDETLEQFLRLPPEQILLRWFNYHLKQANWNRRVTNFSKDVSDGENYTILLNQLDPALCSKAPLQTTDLMERAEQVLQNAEKLDCRKYLT</Hsp_hseq>
      <Hsp_midline>EN ++ +   +     +V++ S+ I++G   LILGL+W +I           LH  +   + +DE  ++  +  P+Q LL W  + L     +  ++NFS+D  DG     L++   P LC     +  D++   E V  N ++     YL+</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>105</Statistics_hsp-len>
      <Statistics_eff-space>4424365464</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>8</Iteration_iter-num>
  <Iteration_query-ID>Query_8</Iteration_query-ID>
  <Iteration_query-def>PMZ_0042159-RA transcript Note:&quot;Protein of unknown function&quot; offset:221 AED:1.00 eAED:1.00 QI:221|0|0|0|0.11|0.2|10|0|427</Iteration_query-def>
  <Iteration_query-len>1505</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>94</Statistics_hsp-len>
      <Statistics_eff-space>933522469</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>9</Iteration_iter-num>
  <Iteration_query-ID>Query_9</Iteration_query-ID>
  <Iteration_query-def>PMZ_0042157-RA transcript Note:&quot;Similar to SLMAP Sarcolemmal membrane-associated protein (Oryctolagus cuniculus)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.37|0.44|9|240|227</Iteration_query-def>
  <Iteration_query-len>924</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YHR115C</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:VIII:340109:341359:-1 gene:YHR115C transcript:YHR115C_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:DMA1 description:Ubiquitin-protein ligase (E3); controls septin dynamics, spindle position checkpoint (SPOC) with ligase Dma2p by regulating recruitment of Elm1p to bud neck; regulates levels of eIF2 subunit Gcd11p, as well as abundance, localization, and ubiquitination of Cdk inhibitory kinase Swe1p; ubiquitinates cyclin Pcl1p; ortholog of human RNF8, similar to human Chfr; contains FHA, RING fingers; DMA1 has a paralog, DMA2, that arose from the whole genome duplication [Source:SGD;Acc:S000001157]</Hit_def>
  <Hit_accession>YHR115C</Hit_accession>
  <Hit_len>416</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>47.3654</Hsp_bit-score>
      <Hsp_score>111</Hsp_score>
      <Hsp_evalue>1.55857e-06</Hsp_evalue>
      <Hsp_query-from>232</Hsp_query-from>
      <Hsp_query-to>354</Hsp_query-to>
      <Hsp_hit-from>235</Hsp_hit-from>
      <Hsp_hit-to>275</Hsp_hit-to>
      <Hsp_query-frame>1</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>19</Hsp_identity>
      <Hsp_positive>28</Hsp_positive>
      <Hsp_gaps>0</Hsp_gaps>
      <Hsp_align-len>41</Hsp_align-len>
      <Hsp_qseq>LLQDTRSSNGTFVNGQRLGKSGEESAPYQLYSGDVLQFGVD</Hsp_qseq>
      <Hsp_hseq>FLKDVKSSSGTFLNHQRLSSASTTSKDYLLHDGDIIQLGMD</Hsp_hseq>
      <Hsp_midline> L+D +SS+GTF+N QRL  +   S  Y L+ GD++Q G+D</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>89</Statistics_hsp-len>
      <Statistics_eff-space>509540073</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>10</Iteration_iter-num>
  <Iteration_query-ID>Query_10</Iteration_query-ID>
  <Iteration_query-def>PMZ_0042156-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|0.33|0.3|10|367|470</Iteration_query-def>
  <Iteration_query-len>1780</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1138959366</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>11</Iteration_iter-num>
  <Iteration_query-ID>Query_11</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054762-RA transcript Note:&quot;Protein of unknown function&quot; offset:224 AED:0.56 eAED:0.56 QI:224|0|0.5|0.5|1|1|2|0|1204</Iteration_query-def>
  <Iteration_query-len>3839</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>101</Statistics_hsp-len>
      <Statistics_eff-space>2647516126</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>12</Iteration_iter-num>
  <Iteration_query-ID>Query_12</Iteration_query-ID>
  <Iteration_query-def>PMZ_0036718-RA transcript Note:&quot;Similar to Mgll Monoglyceride lipase (Mus musculus)&quot; offset:355 AED:0.42 eAED:0.42 QI:355|0.75|0.6|1|0|0|5|0|210</Iteration_query-def>
  <Iteration_query-len>988</Iteration_query-len>
<Iteration_hits>
<Hit>
  <Hit_num>1</Hit_num>
  <Hit_id>YKL094W</Hit_id>
  <Hit_def>pep chromosome:R64-1-1:XI:263349:264290:1 gene:YKL094W transcript:YKL094W_mRNA gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:YJU3 description:Monoglyceride lipase (MGL); functional ortholog of mammalian MGL, localizes to lipid particles and membranes, also member of the eukaryotic serine hydrolase family [Source:SGD;Acc:S000001577]</Hit_def>
  <Hit_accession>YKL094W</Hit_accession>
  <Hit_len>313</Hit_len>
  <Hit_hsps>
    <Hsp>
      <Hsp_num>1</Hsp_num>
      <Hsp_bit-score>44.669</Hsp_bit-score>
      <Hsp_score>104</Hsp_score>
      <Hsp_evalue>9.20728e-06</Hsp_evalue>
      <Hsp_query-from>434</Hsp_query-from>
      <Hsp_query-to>736</Hsp_query-to>
      <Hsp_hit-from>19</Hsp_hit-from>
      <Hsp_hit-to>124</Hsp_hit-to>
      <Hsp_query-frame>2</Hsp_query-frame>
      <Hsp_hit-frame>0</Hsp_hit-frame>
      <Hsp_identity>33</Hsp_identity>
      <Hsp_positive>50</Hsp_positive>
      <Hsp_gaps>5</Hsp_gaps>
      <Hsp_align-len>106</Hsp_align-len>
      <Hsp_qseq>NADGLSIYCRYWRPTQG--KPRGLVHVIHGAGEHCRRYDEVASRLSALGYFAFAHDHVGHGQSEGPRMQVSDFQVFVRDTLQHF---DLICKRYPDLPIFLLGHSM</Hsp_qseq>
      <Hsp_hseq>NFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWGHSM</Hsp_hseq>
      <Hsp_midline>N DG      +W    G  + RG V +IHG GE+ +    +   LS  GY +F  D  G G +   R +    +  V + L+HF   +L   +   +P+F+ GHSM</Hsp_midline>
    </Hsp>
  </Hit_hsps>
</Hit>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>554496013</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
</Iteration>
<Iteration>
  <Iteration_iter-num>13</Iteration_iter-num>
  <Iteration_query-ID>Query_13</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054763-RA transcript Note:&quot;Protein of unknown function&quot; offset:0 AED:0.50 eAED:0.66 QI:0|0|0.2|0.6|1|1|5|0|350</Iteration_query-def>
  <Iteration_query-len>1053</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>91</Statistics_hsp-len>
      <Statistics_eff-space>601501420</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>14</Iteration_iter-num>
  <Iteration_query-ID>Query_14</Iteration_query-ID>
  <Iteration_query-def>PMZ_0027897-RA transcript Note:&quot;Similar to Svep1 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Mus musculus)&quot; offset:159 AED:0.44 eAED:0.44 QI:159|0.92|0.78|0.92|0|0|14|37|518</Iteration_query-def>
  <Iteration_query-len>1753</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1118375763</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>15</Iteration_iter-num>
  <Iteration_query-ID>Query_15</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054766-RA transcript Note:&quot;Similar to Lrtm2 Leucine-rich repeat and transmembrane domain-containing protein 2 (Mus musculus)&quot; offset:0 AED:0.09 eAED:0.17 QI:0|0|0|0.33|1|1|3|0|336</Iteration_query-def>
  <Iteration_query-len>1011</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>90</Statistics_hsp-len>
      <Statistics_eff-space>573056549</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>16</Iteration_iter-num>
  <Iteration_query-ID>Query_16</Iteration_query-ID>
  <Iteration_query-def>PMZ_0004062-RA transcript Note:&quot;Similar to ucma Unique cartilage matrix-associated protein (Danio rerio)&quot; offset:0 AED:1.00 eAED:1.00 QI:0|0|0|0|1|1|3|2067|88</Iteration_query-def>
  <Iteration_query-len>2334</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>97</Statistics_hsp-len>
      <Statistics_eff-space>1548503427</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>17</Iteration_iter-num>
  <Iteration_query-ID>Query_17</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054768-RA transcript Note:&quot;Similar to PHYH Phytanoyl-CoA dioxygenase, peroxisomal (Homo sapiens)&quot; offset:0 AED:0.39 eAED:0.39 QI:0|0|0|0.5|1|1|4|0|146</Iteration_query-def>
  <Iteration_query-len>441</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>81</Statistics_hsp-len>
      <Statistics_eff-space>157044822</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>18</Iteration_iter-num>
  <Iteration_query-ID>Query_18</Iteration_query-ID>
  <Iteration_query-def>PMZ_0029974-RA transcript Note:&quot;Protein of unknown function&quot; offset:57 AED:1.00 eAED:1.00 QI:57|0|0|0|0|0|3|0|87</Iteration_query-def>
  <Iteration_query-len>321</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>76</Statistics_hsp-len>
      <Statistics_eff-space>74786477</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>19</Iteration_iter-num>
  <Iteration_query-ID>Query_19</Iteration_query-ID>
  <Iteration_query-def>PMZ_0026020-RA transcript Note:&quot;Similar to CACNA2D2 Voltage-dependent calcium channel subunit alpha-2/delta-2 (Homo sapiens)&quot; offset:0 AED:0.19 eAED:0.19 QI:0|0|0|0.72|0.4|0.45|11|0|276</Iteration_query-def>
  <Iteration_query-len>831</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>88</Statistics_hsp-len>
      <Statistics_eff-space>440987463</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
<Iteration>
  <Iteration_iter-num>20</Iteration_iter-num>
  <Iteration_query-ID>Query_20</Iteration_query-ID>
  <Iteration_query-def>PMZ_0054794-RA transcript Note:&quot;Similar to Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 (Rattus norvegicus)&quot; offset:0 AED:0.15 eAED:0.15 QI:0|0.5|0.6|0.6|0.5|0.4|5|1248|184</Iteration_query-def>
  <Iteration_query-len>1803</Iteration_query-len>
<Iteration_hits>
</Iteration_hits>
  <Iteration_stat>
    <Statistics>
      <Statistics_db-num>6600</Statistics_db-num>
      <Statistics_db-len>2914067</Statistics_db-len>
      <Statistics_hsp-len>95</Statistics_hsp-len>
      <Statistics_eff-space>1157255902</Statistics_eff-space>
      <Statistics_kappa>0.041</Statistics_kappa>
      <Statistics_lambda>0.267</Statistics_lambda>
      <Statistics_entropy>0.14</Statistics_entropy>
    </Statistics>
  </Iteration_stat>
  <Iteration_message>No hits found</Iteration_message>
</Iteration>
</BlastOutput_iterations>
</BlastOutput>

